AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05379062 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Receptive Music Group
Description: The participants of the Receptive Music Group will individually listen to the already researched CD for Parkinson's patients (Bernatzky, Wendtner, Volc, 2012) at home at the same time on one weekday.
Study NCT05388838 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood sample
Description: Blood sample will be taken at D0: 63 ml (7 tubes of 9 ml),
Study NCT06510413 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Loxoprofen Sodium Patches(test product )
Description: Single dose of one patch in each period; Apply for 24 hours each time
Study NCT06370832 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IMT and exercise training group
Description: Participants will perform supervised exercise training per usual care and will be provided with a personalized prescription for an IMT program during the pre-transplant phase. Participants will perform two daily IMT sessions of 30 breaths (\< 5 minutes/session) 5 days per week in their home environment or in-person visits. IMT intensity will be progressed weekly by 5-10% of the baseline maximal inspiratory pressure if the Borg Dyspnea score is \< 7.
Study NCT05376969 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWP16001
Description: DWP16001 Tablets
Study NCT05417061 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Saliva and serum sampling
Description: Saliva were collected to analyze the selected markers as unstimulated samples during the early hours of the day. The saliva was centrifuged and then transferred into Eppendorf tubes.~Venous puncture was performed after saliva collection and 10 mL of blood samples were collected by qualified staff (MFD) from each participant. Saliva and serum were then stored at -80 °C until analysis.
Study NCT05417061 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Saliva and serum sampling
Description: Saliva were collected to analyze the selected markers as unstimulated samples during the early hours of the day. The saliva was centrifuged and then transferred into Eppendorf tubes.~Venous puncture was performed after saliva collection and 10 mL of blood samples were collected by qualified staff (MFD) from each participant. Saliva and serum were then stored at -80 °C until analysis.
Study NCT05632705 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Closing pack
Description: A closing pack, new sterile gloves and new sterile drapes will be used when commencing closure of the sheath and skin
Study NCT05143125 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Decitabine combined with NK cell infusion
Description: Decitabine combined with NK cell infusion
Study NCT06075030 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AND017
Description: Oral administration of AND017 capsules three times per week
Study NCT05705037 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: CPP-ACPF
Description: CPP-ACPF mousse (MI Paste®) was applied with a microbrush on the cervical buccal surface of each tooth for 5 minutes and it was subsequently distributed for 20 seconds with a rubber cup coupled to a low speed handpiece. Right after, a sham therapy was performed, using RAFFAELLO 980 BIO - Dental Medical Technologies - DMT S.r.l. Although the device was switched on, the hand piece did not work and the sound was emitted by a mobile phone. The tip of the laser device was positioned on two areas for each dental element, located one in the center of the cervical region and the other in the middle third of the crown.
Study NCT05081726 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Functional MRI
Description: Series of MRI scans of the brain
Study NCT05159453 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Human Insulin
Description: International Unit for International Unit exchange of transdermally delivered Human Insulin for injected Human Insulin or combinations of basal and fast-acting insulins.
Study NCT05159453 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Finger-actuated, Metered Pump Sprayer
Description: Stock, pharmaceutical grade High Density Polyethylene (HDPE) bottle and HDPE nylon and stainless steel finger-actuated pump sprayer delivering 0.2 mL per pump.
Study NCT05417165 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pneumococcal 20-valent Conjugate Vaccine
Description: Given IM
Study NCT06152900 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accufit
Description: Magnet-based and Direct muscle stimulation devices are commonly used to generate current flow through the muscles in order to activate the muscle. The Accufit Electrical Muscle Stimulation device is an FDA cleared device having a two-channel stimulator that provides up to 8 electrodes with waveforms of interferential and biphasic for muscle stimulation. The Accufit system is indicated for relaxation of muscles, muscle re-education, reduction of pain and increased local blood circulation.~Muscle stimulation technology has been around for many decades and has been shown to be safe and effective for a variety of clinical applications. The foundational basis for the technology revolves around electrical current flowing through the muscle can be used to activate the muscle.
Study NCT05705037 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: PBMT
Description: A placebo mousse (Elmex Junior®) was applied with a microbrush on the cervical buccal surface of each tooth for 5 minutes and it was subsequently distributed for 20 seconds with a rubber cup coupled to a low speed handpiece. Right after, a PBMT was performed, using RAFFAELLO 980 BIO - Dental Medical Technologies - DMT S.r.l. The tip of the laser device was positioned on two areas for each dental element, located one in the center of the cervical region and the other in the middle third of the crown. The parameters used were: wavelength 980 nm, power 4 W, irradiation area1 cm2, application time 15 sec per 1 cm2, energy density 60 J/cm2
Study NCT05705037 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CPP-ACPF+PBMT
Description: CPP-ACPF mousse (MI Paste®) was applied with a microbrush on the cervical buccal surface of each tooth for 5 minutes and it was subsequently distributed for 20 seconds with a rubber cup coupled to a low speed handpiece. Right after, a PBMT was performed, using RAFFAELLO 980 BIO - Dental Medical Technologies - DMT S.r.l. The tip of the laser device was positioned on two areas for each dental element, located one in the center of the cervical region and the other in the middle third of the crown. The parameters used were: wavelength 980 nm, power 4 W, irradiation area1 cm2, application time 15 sec per 1 cm2, energy density 60 J/cm2.
Study NCT04765839 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational, culturally appropriate COVID-19 messages
Description: Educational, culturally appropriate COVID-19 messages will be developed and shared by RHCP.
Study NCT04926090 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Support Plan - Clinician Guided (ESP-C)
Description: The Emotional Support Plan (ESP) is designed to help prepare students to cope with stress experienced during postsecondary education. The ESP-C is delivered by a clinician in 2 sessions.
Study NCT04926090 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Support Plan - Self Guided (ESP-S)
Description: The Emotional Support Plan (ESP) is designed to help prepare students to cope with stress experienced during postsecondary education. The ESP-S is created by the participant on their own, with the support of self-guided materials.
Study NCT05417165 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pneumococcal 20-valent Conjugate Vaccine
Description: Given IM
Study NCT05417165 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pneumococcal Polyvalent Vaccine
Description: Given IM
Study NCT06174389 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Weight Loss Program
Description: Behavioral Weight Loss Program is a modified version of the Diabetes Prevention Program.
Study NCT05043519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FAM-NP41
Description: The patients will be injected with FAM-NP41 in one dose intravenously 2 hours prior to the dural incision.
Study NCT05411523 — intervention group
Intervention type: OTHER
Intervention: Quality-of-Life Assessment
Description: Complete quality of life assessment
Study NCT05411523 — intervention group
Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study NCT05411523 — intervention group
Intervention type: PROCEDURE
Intervention: Spinal Cord Stimulation
Description: Receive spinal cord stimulation therapy
Study NCT04709484 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: USG-guided steroid injection
Description: In the palpation-guided group, the most painful point will be found by palpation on the calcaneus boIn the USG-guided group, steroid injection will be made to the area where the fascia is thickened under USG guidance. The content of the steroid solution will be 1 ml of 1% Lidocaine + 1 ml (40 mg) methylprednisolone.ne and steroid injection will be made to that part. The content of the steroid solution will be 1 ml of 1% Lidocaine + 1 ml (40 mg) methylprednisolone.
Study NCT04709484 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palpation-guided steroid injection
Description: In the palpation-guided group, the most painful point will be found by palpation on the calcaneus bone and steroid injection will be made to that part. The content of the steroid solution will be 1 ml of 1% Lidocaine + 1 ml (40 mg) methylprednisolone.
Study NCT05342259 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Caudal nerve block /neuroaxial
Description: Technique of the caudal block The patient was placed in lateral decubitus position for blind caudal epidural block. A line was drawn to connect the bilateral posterior superior iliac crests and used as one side of an equilateral triangle; then the location of the sacral hiatus was approximated by palpating the sacral cornua as 2 bony prominences, the sacral hiatus was identified as a dimple in between. A needle was inserted at 45 degrees to the sacrum and redirected if the posterior surface of sacral bone was contacted.~A subjective feeling of loss of resistance suggests piercing the sacral ligament.The whoosh test, performed by auscultation at the thoracolumbar region with a stethoscope while injecting 2 mL of air, Palpating for subcutaneous bulging on rapid injection of 5 mL air or saline had a positive predictive value of 83% and a negative predictive value of 44%.
Study NCT05342259 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal penile nerve block
Description: Technique of Dorsal penile nerve block:~Under aseptic technique and under ultrasound guidance. A 'hockey-stick' probe was used, covered by transparent sterile dressing. The probe was placed vertically over the pubic symphysis and the base of the penile shaft. With adjustment of the probe, a sagittal view of the penile shaft was produced. Scarpa's fascia was seen as a hyperechoic line superficial to the penile shaft. Under real-time guidance, the needle was inserted and advanced until its tip laid deep to Scarpa's fascia (i.e., within the subpubic space), where local anesthetic was deposited. The local anesthetic solution injected was 0.5% bupivacaine in a recommended volume. (2 ml up to 3 years and an additional 1 ml for each3 years up to maximum 6 ml).
Study NCT05342259 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Combined caudal and dorsal penile nerve block
Description: Combined techniques of caudal and dorsal penile nerve block
Study NCT05560984 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: cervical internal os plasty
Description: A long Allis forceps will be passed through the uterine incision and used to grasp the anterior lip of the cervix, pulling the cervix upwards into the uterine cavity. An assistant sometimes needs to elevate the cervix upwards from the vaginal aspect. The anterior lip of the cervix will be sutured to the anterior wall of the lower uterine segment using two or three simple interrupted absorbable stitches (Vicryl or Vicryl rapid no. 0). This aids to compress the bleeding sites of the placental bed and support the very thin lower uterine segment. If the placenta was implanted posteriorly and the bleeding areas will be mainly from the posterior wall of the uterus, the same procedure could be repeated using the posterior lip of the cervix. A Hegar dilator (size 12) will be inserted in a retrograde manner from the abdominal aspect toensure patency of the cervical canal .
Study NCT06152757 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: First dose
Description: 1.0×10\^8cells,Intravenous infusion，1 subject is planned to be enrolled
Study NCT06152757 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Second dose
Description: 3.0×10\^8cells,Intravenous infusion，3 subject is planned to be enrolled
Study NCT06152757 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: The third dose
Description: 1.0×10\^9cells,Intravenous infusion，3 subject is planned to be enrolled
Study NCT06152757 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: The fourth dose
Description: 3.0×10\^9cells,Intravenous infusion，3 subject is planned to be enrolled
Study NCT05069454 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 vaccine Observation of individuals who receive the COVID-19 vaccine
Description: To measure the effectiveness of COVID-19 vaccines against symptomatic laboratory-confirmed SARS-CoV-2 infection amongst hospital level health workers eligible for vaccination.
Study NCT06050668 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Essential Amino Acid Supplementation
Description: Powdered supplement that can be mixed into beverage of choice. Ingredients: Zinc, Vitamin A, Vitamin C, Whey Protein, Leucine, Calcium, Vitamin D, Glutamine, Boron, Turmeric, Bioperine, Iron, β-hydroxy β-methylbutyrate (HMB)
Study NCT05270902 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CytoSorb Adsorber
Description: Polymer based adsorber system for the elimination of cytokines
Study NCT05402566 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Deuterium metabolic imaging
Description: MRI after oral administration of 75g of \[6,6'-2H2\]glucose.
Study NCT06188039 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Superior vena cava collapsibility index
Description: After induction of general anaesthesia following interventions will be performed.~1. Insertion of a tranesophageal echocardiography probe~2. Measurement of SVC-CI~3. Measurement of LVOT-VTI prior to fluid bolus~4. Fluid bolus (250ml of crystalloid)~5. Measurement of LVOT-VTI after fluid bolus~Several volume trials per patient will be allowed, until safety criteria are met. In such cases further testing will be stopped.
Study NCT06188039 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Superior vena cava collapsibility index
Description: After induction of general anaesthesia following interventions will be performed.~1. Insertion of a tranesophageal echocardiography probe~2. Measurement of SVC-CI~3. Measurement of LVOT-VTI prior to fluid bolus~4. Fluid bolus (250ml of crystalloid)~5. Measurement of LVOT-VTI after fluid bolus~Several volume trials per patient will be allowed, until safety criteria are met. In such cases further testing will be stopped.
Study NCT06188039 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PEEP elevation
Description: A transient elevation of positive end-expiratory pressure (PEEP) will be applied, in order to validate SVC-CI in the setting of elevated PEEP.~A PEEP level of 8-10cmH2O will be applied for 1 minute prior to every measurement of SVC-CI. Then the previous PEEP level will be reinstated.
Study NCT04891510 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: REVOLVE Advanced Adipose System
Description: The REVOLVE system is an all-in-one fat processing device that harvests, filters, actively washes, and removes strands from lipoaspirate and allows for reinjection without any additional manipulation (REVOLVE 2020).
Study NCT04891510 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LipoGrafter
Description: The LipoGrafter system is designed to be a start-to-finish closed system with minimal processing of the lipoaspirate, minimizing the risk of contamination and fat cell damage (LipoGrafter 2020).
Study NCT04891510 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Viality
Description: The Viality system uses the AuraClens solution that acts as a surfactant to bring impurities like blood, free oil, and cellular debris into solution, where they can be flushed out through suction.
Study NCT05743439 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early Augmentative and Alternative Communication (AAC) Intervention
Description: Caregivers will receive 24, 50 min intervention sessions twice a week for three months. During each intervention session, the therapist provides instruction and coaching on using AAC and a set of evidence-based language support strategies. Strategies are taught sequentially in three phases: (1) Responding to all Communication, (2) Teaching Words, and (3) Creating Communication Opportunities. Caregivers practice using the AAC intervention strategies during three, five-minute routines with their children. Therapists coach the caregiver on using the targeted strategies during these routines, encouraging caregivers to reflect on their implementation, and developing a plan to use the AAC strategies during activities not practiced during the intervention session. The AAC intervention is provided to families using an evidence-based service delivery model, Family Guided Routines Based Intervention.
Study NCT05413356 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Oral ruxolitinib twice daily
Study NCT05174351 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: beta blocker discontinuation
Description: beta blocker discontinuation
Study NCT05822284 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: NGS and ctDNA-MRD detection
Description: NGS and ctDNA-MRD detection
Study NCT04682522 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metronidazole Oral
Description: 250 mg Three times a day
Study NCT04490616 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rTMS treatment
Description: A two-site rTMS stimulation delivered by a Magstim unit featuring a double 70 mm cooled coil will be applied.~MCI patients will be randomly assigned to one of the two study groups:~1. RR-Gr will receive 4 weeks of rTMS stimulation of the right temporo-parietal junction (RTPJ) and medial prefrontal cortex (MPFC);~2. PL-Gr will receive sham stimulation of the RTPJ and MPFC during the first 2 weeks followed by 2 weeks of real stimulation. Each week of rTMS treatment will consist of five sessions (50 min, one per day).~For each area target, a total of 2000 pulses at 20Hz, 3-s train duration, and 28-s inter-train interval at 100% motor threshold (MT) will be delivered per session. A fixed intensity of MT will ensure a more consistent spatial spread of TMS effects in subjects' brains not influenced by differences in individual MT. In the sham condition, a sham coil will be used.~Each session lasted for about 60 min including time for set up and 50 min of stimulation.
Study NCT04490616 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: rTMS treatment
Description: A two-site rTMS stimulation delivered by a Magstim unit featuring a double 70 mm cooled coil will be applied.~MCI patients will be randomly assigned to one of the two study groups:~1. RR-Gr will receive 4 weeks of rTMS stimulation of the right temporo-parietal junction (RTPJ) and medial prefrontal cortex (MPFC);~2. PL-Gr will receive sham stimulation of the RTPJ and MPFC during the first 2 weeks followed by 2 weeks of real stimulation. Each week of rTMS treatment will consist of five sessions (50 min, one per day).~For each area target, a total of 2000 pulses at 20Hz, 3-s train duration, and 28-s inter-train interval at 100% motor threshold (MT) will be delivered per session. A fixed intensity of MT will ensure a more consistent spatial spread of TMS effects in subjects' brains not influenced by differences in individual MT. In the sham condition, a sham coil will be used.~Each session lasted for about 60 min including time for set up and 50 min of stimulation.
Study NCT06158555 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 250 ML NaCl 4.5 MG/ML Injection
Description: Bolus 250 ml crystalloid. Usually 0.9% saline or compound sodium lactate solution at discretion of attending clinician
Study NCT05790902 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Silodosin
Description: The patients used Silodosin for Medical expulsive therapy of ureteric calculi
Study NCT05790902 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamsulosin
Description: The patients used Tamsulosin for Medical expulsive therapy of ureteric calculi
Study NCT05499689 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: 2.5 cc bupivacain injection will be administered by approaching the greater occipital nerve under ultrasound guidance.
Study NCT05499689 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous pulsed radiofrequency qurrent
Description: Pulsed radiofrequency current will be applied through transcutaneous pads adhered over the greater occipital nerve trace on the nape.
Study NCT05119244 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: blood and hair sampling
Description: 3.5 ml blood sample Hair sample
Study NCT01596413 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sancuso
Description: granisetron transdermal system
Study NCT01596413 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IV granisetron
Description: IV