AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06533254 — intervention group
Intervention type: BEHAVIORAL
Intervention: Behavioral nudges
Description: Patients with Chronic Kidney Disease, participants will be provided with their predicted personalized nudge to increase their likelihood of either maintaining their choice of peritoneal dialysis, or switching from hemodialysis to peritoneal dialysis.~Participants will respond to a survey that utilizes open and closed ended questions, asking broad questions about kidney failure and associated behaviors (e.g. diet, attitudes towards treatment). The open-ended questions will gather a natural language sample of 100-300 words whilst closed questions will capture data using Likert scale and multiple-choice responses.
Study NCT06498453 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Trak-Physio knee condition
Description: The exercise protocol designed for knee conditions is carried out through Trak, the digital rehabilitation tool.
Study NCT06498453 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Trak-Physio in shoulder condition
Description: The exercise protocol designed for knee conditions is carried out through Trak, the digital rehabilitation tool.
Study NCT06498453 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Knee conventional rehabilitation program
Description: Exercise protocol with the methodology of conventional clinical practice.
Study NCT06498453 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Shoulder conventional rehabilitation program
Description: Exercise protocol with the methodology of conventional clinical practice.
Study NCT06150885 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HLA-G-CAR.BiTE allogeneic γδ T cells
Description: Phase I is a multiple escalating dose, single arm, open-label and 3+3 design that implemented with five cohorts: low dose for single administration, low dose for twice administrations for 2 weeks, low, middle and high dose for 4 repeated administrations for 4 weeks.~Phase IIa is a single-arm, open-label and dose-expansion study and the effective dose of CAR-positive cells will be administered to 27 evaluable subjects with TNBC, NSCLC, CRC or GBM via intravenous infusion weekly for 4 weeks.
Study NCT05435885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary Tele-Rehabilitation
Description: 12 supervised training sessions via a specific mobile messenger during four weeks. (3 sessions/week)
Study NCT05435885 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control (Education)
Description: Usual care with only one educational session.
Study NCT05133167 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Balloon Tamponade or B-Lynch
Description: In group A, balloon tamponade (using Foley catheter 28 Fr) was used intra-operatively to prevent post-partum hemorrhage. Post-operative blood loss within first 24 hours was estimated by measuring the amount of blood collected in Foley balloon tamponade bag, in milliliters. In group B, B lynch suture was used intra-operatively to prevent post-partum hemorrhage. Post-operative blood loss within first 24 hours was estimated by the weight difference of the pads before and after patient use (1-gram weight difference = 1 ml blood volume lost). Mean blood loss within first 24 hours post procedure, was compared in both the groups for outcome measurement.
Study NCT04833140 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Estradiol patch
Description: The patch will provide 100mcg of estradiol daily.
Study NCT04833140 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo patch will contain no estradiol.
Study NCT05890911 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Polysomnography
Description: Each of the patients will undergo polysomnography
Study NCT05890911 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood dopamine level measurement
Description: In each of the patients blood dopamine level will be measured
Study NCT05890911 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Genetical test
Description: Each of the patients will undergo genetical test focusing on selected single nucleotide polymorphisms within genes regulating the concentration of dopamine - the gene responsible for production of the enzyme catechol-O-methyltransferase (COMT) - rs4680 and rs6269 and genes encoding receptors dopamine (DRD1 - rs686, rs5327 and DRD2 - rs1800497).
Study NCT05577962 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: T group
Description: OFA scheme (group T) was given dexamethasone 8mg for anti-inflammatory and antiemetic before operation, flurbiprofen axetil 50mg for preemptive analgesia, and dexmedetomidine was infused under ECG monitoring at an initial rate of 0.5 μ G/kg (more than 10min), then changed to 0.2ug/kg/h, and stopped infusion 20 minutes before operation closure. Before induction, lidocaine (1mg/kg), esketamine (0.5mg/kg), propofol (1-2mg/kg) and rocuronium (0.6mg/kg) were infused slowly, and endotracheal intubation was carried out when the anesthetic was fully effective and the BIS value was about 40. After successful intubation, an experienced anesthesiologist guided by ultrasound performed bilateral superficial cervical plexus block with 0.5% ropivacaine and injected 3-4ml at two points respectively; During the operation, sevoflurane (MAC1.0 - 1.4) was used to maintain the depth of anesthesia
Study NCT06498180 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: oral hygiene instruction
Description: Instructions and demonstrations for using manual toothbrushes Instructions and demonstrations for using dental floss or interdental brushes
Study NCT06498180 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: oral hygiene instruction
Description: Instructions and demonstrations for using manual toothbrushes Instructions and demonstrations for using dental floss or interdental brushes
Study NCT05087446 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early assessment team
Description: Early assessment team (EAT):The patients receive their first assessment by an early clarification team within a few weeks after the team receiving the referral. The team then decides whether further assessment and/or treatment should be given in the general outpatient clinic, and/or whether any other follow-up may be appropriate. In the first meeting the patient preferably meets two therapists, who conduct a semi-structured interview with focus on health and level of functioning. If considered appropriate, the team may offer a short-term intervention.
Study NCT05087446 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Admission to General psychiatric outpatient clinic
Description: Ordinary procedures for admission to an outpatient clinic are followed in accordance with the Norwegian Directorate of Health's national prioritization guide. Referrals are assessed on the basis of severity and placed on a regular waiting list (usually a waiting period of 1-3 months). The patients receive their first personal assessment from a therapist in a general outpatient clinic who takes a position on what is to be initiated and, if necessary, offers further assessment / treatment in accordance with procedures in the outpatient clinics. This is not standardized beyond current practice.
Study NCT06181058 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: escape room game
Description: Participants will be informed about the game (15 minutes). They will complete the game by solving puzzles within the framework of the oncology patient scenario (approximately 30 minutes). There will be a debriefing session at the end of the escape game (15 minutes).
Study NCT05722769 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CSTOP Now!
Description: Child sex trafficking stops with you. Implement and evaluate the effectiveness of a multi-level bystander-informed program (CSTOP Now!) aimed at Kentucky public middle school staff. Participants will be trained to use the See It To Stop It Indicator Tool (SITSII) by using tiers of concern (clear concern, possible concern, and monitor of emerging concern). The SITSII tool directs the bystander actions to Decide, Directly Intervene, Disrupt, Delegate, and Document.
Study NCT05722769 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevent Child Abuse Kentucky Online Training
Description: The Kentucky State Police, in association with Prevent Child Abuse Kentucky, have developed videos we invite active comparator schools to review which also include how to identify and report child sex trafficking.
Study NCT05355610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gentamicin
Description: Intratympanic gentamicin and dexamethasone administered in two doses one week apart
Study NCT05355610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Intratympanic gentamicin and dexamethasone administered in two doses one week apart
Study NCT05177133 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: PO Capecitabine
Study NCT05177133 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: IV Oxaliplatin
Study NCT05177133 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Retifanlimab
Description: IV retifanlimab
Study NCT04722549 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Cellulose
Study NCT04722549 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Butyrate
Description: Sodium butyrate
Study NCT05554965 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Remifentanil maintenance analgesic dose was 1.2-9 μg/kg/h. If the CPOT score ≥3 at the time of maintenance administration, dose adjustment can be considered. Propofol was used for sedation at a loading dose of 0.5mg/kg and a maintenance dose of 1.5mg/kg/h.
Study NCT05554965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam besylate
Description: Remifentanil was administered at a maintenance dose of 1.2-9 μg/kg/h for analgesia. If CPOT score ≥3 during maintenance administration, dose adjustment could be considered. For sedation, remazolam besylate was given a load of 0.1-0.2mg/kg and a maintenance dose of 0.1-0.3mg/kg/h.
Study NCT05516173 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood Pressure Monitoring, Ambulatory
Description: To monitor the blood pressure during 24 hours.
Study NCT05315778 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: autologous anti-BCMA chimeric antigen receptor T cells
Description: Lymphoadenodepletion chemotherapy with FC (fludarabine 30mg/ m2 for 3 consecutive days and cyclophosphamide 300mg/m2 for 3 consecutive days) will be given at day -5, -4 and -3 before CAR T-cells infusion. A total of 1.0-2.0×10e7/Kg autologous anti-BCMA CAR T-cells will be infused by dose-escalation after the lymphoadenodepletion chemotherapy. Dose of CAR T-cells are allowed to be adjusted according to the severity of cytokine release syndrome.
Study NCT04545554 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Romosozumab
Description: Participants will receive multiple doses of romosozumab via a SC injection.
Study NCT04545554 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Calcium
Description: All participants will receive daily supplements of elemental calcium.
Study NCT04545554 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: All participants will receive daily supplementation with vitamin D.
Study NCT05665179 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Removing Barriers to Recovery
Description: Experimental patients are provided no-cost legal services in-person at addiction treatment centers using an online platform
Study NCT04781842 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Boxing exercise program
Description: Participants attended an hour long class once a week for 12 weeks. Included in class was a warm up, boxing activities including weight shifting, kicking, and punching bags, strengthening activities and a cool down.
Study NCT06440577 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio-visual stimuli (Neutral-Relaxing)
Description: Audio instruction for participant to allow themselves to experience their feelings followed by 3-min passive viewing of images of neutral everyday objects (e.g., tools, dirt) and their use (construction, gardening).
Study NCT06440577 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio-visual stimuli (Drug)
Description: Audio instruction for participant to allow themselves to experience their feelings followed by 3-min passive viewing of images of drug paraphernalia (e.g., syringe, tourniquet, heroin) and preparation.
Study NCT06440577 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio-visual stimuli (Non-Food)
Description: Audio instruction for participant to focus their attention on the experimenter followed by 3-min audio-guided viewing of the experimenter opening/unwrapping an everyday object (e.g., box of crayons) and taking out its contents.
Study NCT06440577 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio-visual stimuli (Food)
Description: Audio instruction for participant to focus their attention on the experimenter followed by 3-min audio-guided viewing of the experimenter opening/unwrapping a snack (e.g., chocolate bar, bag of chips) and taking out its contents.
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: baseline serum oxytocin levels
Description: Both cases and controls will be assessed for their baseline serum oxytocin levels
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: Emotional Sensitivity test
Description: To assess the level of emotional sensitivity in the participant
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: Neuro-economical game
Description: A game played to assess the trust-index of participants
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: Childhood Trauma Questionnaire
Description: to assess childhood trauma score
Study NCT05412979 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ST-1891
Description: ST-1891
Study NCT05412979 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levothyroxine
Description: Levothyroxine
Study NCT04952519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amantadine
Description: Patients are treated with high doses of amantadine.
Study NCT04952519 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Amantadine
Description: Patients are treated with high doses of amantadine.
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: Relationships Questionnaire
Description: to assess attachment type
Study NCT06045650 — intervention group
Intervention type: OTHER
Intervention: demographic questionnaire
Description: To obtain basic data on demographics
Study NCT06061484 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: ready-to-use therapeutic food (RUTF)
Description: Standard formulation meeting UNICEF specifications: https://www.unicef.org/supply/sites/unicef.org.supply/files/2023-04/U239977-RUTF-Novel-Specification.pdf
Study NCT06061484 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ready-to-use therapeutic food (RUTF)
Description: Standard formulation meeting UNICEF specifications: https://www.unicef.org/supply/sites/unicef.org.supply/files/2023-04/U239977-RUTF-Novel-Specification.pdf
Study NCT06061484 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Standard weight-based dosing per Ehtiopian national guidelines
Study NCT06061484 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxicillin
Description: Standard weight-based dosing per Ehtiopian national guidelines
Study NCT04887272 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Supervised Exercise Training Protocol
Description: EXT: Supervised EXT will include a progressive individualized program that combines aerobic and resistance protocols. Volume progression will begin with 3-days of supervised training sessions/wk and will increase by 1 session/wk to a maximum of 5-days/wk. Each EXT session will include 30 minutes of aerobic training (15 minutes cycling; 15 minutes treadmill walking/running/elliptical) and 30 minutes of resistance training (specifics below). Considering individual fatigue will be a concern, therefore similar to exercise training standards in COPD, the duration of rest periods may be extended (\~1-3 min) as needed, however, all exercise durations will be completed within a 1.5-hour time slot. On days that EXT and IMET interventions overlap, the training and IMET will be spread out over a 2-hour session as opposed to the 1.5-hour time slot.
Study NCT04887272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Exercise Training Protocol
Description: EXT: Supervised EXT will include a progressive individualized program that combines aerobic and resistance protocols. Volume progression will begin with 3-days of supervised training sessions/wk and will increase by 1 session/wk to a maximum of 5-days/wk. Each EXT session will include 30 minutes of aerobic training (15 minutes cycling; 15 minutes treadmill walking/running/elliptical) and 30 minutes of resistance training (specifics below). Considering individual fatigue will be a concern, therefore similar to exercise training standards in COPD, the duration of rest periods may be extended (\~1-3 min) as needed, however, all exercise durations will be completed within a 1.5-hour time slot. On days that EXT and IMET interventions overlap, the training and IMET will be spread out over a 2-hour session as opposed to the 1.5-hour time slot.
Study NCT04887272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle and Exercise Training
Description: Inspiratory Muscle Training (IMT): All IMT sessions will be performed similar to EXT, with the exception of having 2-3-sessions of at-home IMT training depending on where in the exercise progression the individual is (i.e., Week1 vs week 6). On the days that IMT and exercise training overlap, all training will be spread out over a 2-hour session with periods of IMT training occurring at the beginning, middle and end of the session. Each week will include a measure of Maximal Inspiratory Pressure (MIP) and a Test of Inspiratory Respiratory Endurance (TIRE). The intensity of the IMT will be 50% of the weekly MIP, thus progressive increases in IMT threshold intensity will remain at 50% of the weekly MIP. In contrast, the TIRE protocol will assess respiratory endurance based on the relative baseline intensity. Thus TIRE testing will begin at a MIP intensity of 50% (weeks 1-2), and then progressing to 65% (weeks 3-4), and 80% (weeks 5-6).
Study NCT06071104 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior segment ophthalmic surgery
Description: Cataract surgery during which the crystalline lens (often cloudy) is broken into small pieces and gently removed from the eye with suction (phacoemulsification)
Study NCT06071104 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: UNITY VCS
Description: UNITY Vitreoretinal Cataract System (VCS) with console, remote control, foot controller, UNITY Cataract FMS Pack, and UNITY Anterior Vitrectomy Kit
Study NCT06187974 — intervention group
Intervention type: OTHER
Intervention: observation
Description: observation
Study NCT05276154 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: thermoviscous bulkfill composite (Viscalor)
Description: a relatively new product of composite resin which is transformed from high viscosity to low viscosity by the action of head produced by a heating device.
Study NCT04670055 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BCMA Targeted CAR T-cells
Description: Each subject receive BCMA Targeted CAR T-cells by intravenous infusion
Study NCT06339632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical phrenic nerve stimulation (TEPNS)
Description: The characteristics of the electrical current: biphasic waves, set at a stimulation frequency of 10 Hz, pulse width of 200 μs, rise time of 1.0 second, on time of 1.0 second, fall time of 1.0 second, and off time of 2 seconds, resulting in 12 stimuli per minute. The application of TEPNS will initially be performed by defining the trajectory of the phrenic nerve in the cervical region. The negative pole (active point), a stick with a spherical tip for micro-current of 2 mm will be positioned with slight pressure in the region of the phrenic nerve pathway between the two heads of the sternocleidomastoid muscle. Additionally, at the positive pole (passive point), a self-adhesive electrode sized (2.0 x 2.0 cm) will be positioned on the skin in the shoulder region. The intensity, measured in milliamperes (mA), will be adjusted to the maximum tolerated by the patient. The total stimulation time will be 10 minutes, applied continuously in a single session.
Study NCT06339632 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical diaphragm stimulation (TEDS)
Description: The characteristics of the electrical current are: biphasic waves, set at a stimulation frequency of 30 Hz, pulse width of 400 μs, rise time of 1.0 second, on time of 1.0 second, fall time of 1.0 second, and off time of 2 seconds, resulting in 12 stimuli per minute. Two self-adhesive electrodes sized (5.0 x 5.0 cm) will be used, positioned in the bilateral parasternal region next to the xiphoid process and the other electrode in the intercostal space between the 6th and 7th ribs bilaterally, at the mid-axillary line. The intensity, measured in milliamperes (mA), will be adjusted to the maximum intensity tolerated by the patient until diaphragmatic contraction is observed with the naked eye, without contraction of other muscles in the abdominal region. The total stimulation time will be 10 minutes, applied continuously in a single session.
Study NCT05389046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: Escitalopram
Study NCT05389046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram+Aripiprazole
Description: Escitalopram+Aripiprazole
Study NCT05389046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram+omega-3 PUFAs
Description: Escitalopram+omega-3 PUFAs