AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06170775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodiumhexametaphosphate
Description: Sodiumhexametaphosphate
Study NCT06170775 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MTA
Description: MTA
Study NCT05009524 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iPACES (interactive Physical and Cognitive Exercise System)
Description: iPACES involves a pedal-to-play neuro-exergame in which physical and mental exercise are combined in an interactive way. In this condition a person will pedal to control forward motion in a tablet-based game, such as when pedaling along a virtual path and steering to different assigned errand locations.
Study NCT05009524 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PACE (Physical and Cognitive Exercise)
Description: PACE involves a pedal-while-play experience in which physical and mental exercise are combined in a simultaneous, but not fully interactive way. In this condition a person will pedal while also separately steering in a tablet-based game, such as when pedaling while automatically progressing along a virtual path to different assigned errand locations.
Study NCT05399485 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rimegepant
Description: Randomization Phase: Rimegepant (BHV3000) 75 mg orally disintegrating tablet every other day until Week 12
Study NCT05399485 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Randomization Phase: Placebo tablet to match Rimegepant every other day until Week 12
Study NCT05701917 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ClotTriever System
Description: Mechanical thrombectomy
Study NCT05701917 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.
Description: Anticoagulants are a group of medications that decrease your blood's ability to clot.
Study NCT06452056 — intervention group
Intervention type: DEVICE
Intervention: Rapid Antigen Screening Test
Description: A point-of-care Rapid Antigen Screening Test (RAST) using a lateral flow immunoassay platform with our partner, BioMedomics Inc. The BioMedomics RAST is a lateral flow immunoassay that detects the nucleocapsid protein (NP) antigen of SARS-CoV-2 using a double antibody sandwich assay. The test cassette contains one detection line (T) fixed with anti-SARS-CoV-2 NP antibody and one quality control line (C) fixed with control antibody. When the test sample is treated with lysis buffer and added to the sample well of the test cassette, the fluid will move forward along the test strip via capillary action. If the sample contains NP antigen at levels higher than the limit of detection, the antigen will bind to the NP capture antibody as well as the immobilized detection antibody on the membrane forming a red T line, indicating a positive result. A positive signal at C line provides assurance that the fluid containing the sample material has moved laterally in an appropriate fashion.
Study NCT05743231 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: interpectoral area block + serratus anterior area block group
Description: The interpectoral and serratus anterior area blocks will be applied immediately after general anesthesia is given to the participants under ultrasound guidance. 30 ml of 0.25% bupivacaine will be used for two blocks.
Study NCT01487278 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: misprostol
Description: 600 mcg misoprostol oral
Study NCT01487278 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: UnijectTM
Description: 10 IU oxytocin delivered intramuscularly with UnijectTM
Study NCT05001438 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hidro
Description: Guided by ultrasonography under anesthetic blockage of the circumflex nerve and the supraescapular nerve. The hidrodilatation is achieved by insuflating the articulation with 2 cc of trigon depot + 10 cc 1% mepivacain + 11 cc saline serum.
Study NCT05001438 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hidro
Description: Guided by ultrasonography under anesthetic blockage of the circumflex nerve and the supraescapular nerve. The hidrodilatation is achieved by insuflating the articulation with 2 cc of trigon depot + 10 cc 1% mepivacain + 11 cc saline serum.
Study NCT05001438 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MUA
Description: Movilization under anesthesia
Study NCT04932499 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Participants randomly assigned to this intervention will receive standard of care given to all patients undergoing total knee arthroplasty at our institution as outlined in the Common Care Pathway for Total Joint Replacement. Outcome assessments will be completed pre-operatively, each day while in hospital and 7 and 14 days postoperative.
Study NCT04932499 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Participants randomly assigned to this intervention will receive standard of care given to all patients undergoing total knee arthroplasty at our institution as outlined in the Common Care Pathway for Total Joint Replacement. Outcome assessments will be completed pre-operatively, each day while in hospital and 7 and 14 days postoperative.
Study NCT04932499 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation
Description: In addition to standard of care, participants randomly assigned to the treatment group will be given a 45-60 minute teaching session on mindfulness meditation. Upon completion of this session, participants will be given homework recordings of a body scan exercise and asked to listen to the recording daily for the two-week period prior to surgery. Participants will be asked to listen to their recording immediately prior to their surgery and daily while in hospital. In addition, participants assigned to mindfulness intervention will receive standard of care as outlined in the control group. Outcome assessments will be completed pre-operatively, each day while in hospital and 7 and 14 days postoperative.
Study NCT04850638 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR4640 tablets and furosemide tablets
Description: SHR4640 tablets and furosemide tablets
Study NCT05250310 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Chair Yoga
Description: Yoga poses performed in a chair
Study NCT04757987 — intervention group
Intervention type: OTHER
Intervention: Pain
Description: As above
Study NCT06103825 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solriamfetol
Description: solriamfetol : QD，PO，Day 1-Day 84；
Study NCT04074681 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gambling Internet-based Protocol
Description: Gambling Internet-based protocol is a multimedia interactive and self-help program for problem and pathological gamblers, which will allow individuals to learn and practice adaptive ways to cope with this problem. The main therapeutic modules included in this program are: 1) Motivational for change; 2) Psychoeducation; 3) Stimulus control (e.g. self-prohibition and blocking of usual gambling websites with therapist confirmation) and responsible return of debts; 4) Cognitive restructuring; 5) Emotion regulation; 6) Planning of significant activities; 7) Coping skills and exposure with response prevention; 8) Relapse prevention.
Study NCT05532852 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard-of-care plus Paxlovid
Description: standard-of-care plus Paxlovid
Study NCT05532852 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: standard-of-care
Description: standard-of-care
Study NCT06103825 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo :QD，PO，Day 1-Day 84
Study NCT05904470 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bemnifosbuvir
Description: 550 mg administered orally once a day (QD) for 8 weeks
Study NCT05904470 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruzasvir
Description: 180 mg administered orally once a day (QD) for 8 weeks
Study NCT05033223 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: PTSD evaluation of emergency room staff 9 and 12 months after the end of second lockdown in France during COvid-19 pandemic
Description: PCL-5 autoquestionnaire to make the PTSD diagnosis
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C1 - Standard Perceptual Learning (SPL)
Description: Each trial starts with a fixation point (500ms) after which a Gabor (1° radius, at cut-off SF of 25% accuracy, estimated from Pre-Test CSF, at either 45° or 135°) appears for 128ms. The task is to indicate whether the Gabor was tilted left or right. Gabor contrast will be controlled by a 3/1 staircase (converging on approximately \~80% contrast threshold) across all training sessions.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C1 - Standard Perceptual Learning (SPL)
Description: Each trial starts with a fixation point (500ms) after which a Gabor (1° radius, at cut-off SF of 25% accuracy, estimated from Pre-Test CSF, at either 45° or 135°) appears for 128ms. The task is to indicate whether the Gabor was tilted left or right. Gabor contrast will be controlled by a 3/1 staircase (converging on approximately \~80% contrast threshold) across all training sessions.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C2 - Long Training (LT)
Description: Will be the same as the SPL with the exception that each session in LT will be twice as long as in SPL.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C2 - Long Training (LT)
Description: Will be the same as the SPL with the exception that each session in LT will be twice as long as in SPL.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C3 - Short Staircases (SS)
Description: Will be largely the same as SPL with the only difference being a change to the adaptive procedure. SS will use so-called short-staircases, which are initialized at 60% contrast with steps of .05 log units and employs a 3/1 staircase that after every 40 trials is reset (the short in short-staircases) back to 60% contrast.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C3 - Short Staircases (SS)
Description: Will be largely the same as SPL with the only difference being a change to the adaptive procedure. SS will use so-called short-staircases, which are initialized at 60% contrast with steps of .05 log units and employs a 3/1 staircase that after every 40 trials is reset (the short in short-staircases) back to 60% contrast.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C4 - Mixed Difficulty (MD)
Description: This condition will be identical to SPL with the exception that two staircases - one a 2/1 staircase producing difficulties centered around 60-70% accuracy, the other a 4/1 staircase producing difficulties centered around 85-95% accuracy - will be utilized to control the stimuli.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C4 - Mixed Difficulty (MD)
Description: This condition will be identical to SPL with the exception that two staircases - one a 2/1 staircase producing difficulties centered around 60-70% accuracy, the other a 4/1 staircase producing difficulties centered around 85-95% accuracy - will be utilized to control the stimuli.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C5 - Noise Training (NT)
Description: The NT condition will be the same as SPL with the exception that contrast thresholds will be estimated in 5-different levels of external noise (10%, 15%, 20%, 25%, 30%).
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C5 - Noise Training (NT)
Description: The NT condition will be the same as SPL with the exception that contrast thresholds will be estimated in 5-different levels of external noise (10%, 15%, 20%, 25%, 30%).
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C6 - Training with Flankers (TWF)
Description: TWF will be reasonably different from the standard SPL task. Here, on 50% of trials a target Gabor will be presented at either 45° or 135° (as in SPL) and will be flanked by two collinear Gabors. On the remaining 50% of trials, flankers will be present without a target. TWF is thus a yes/no detection task, which is necessary since the collinear flankers fully indicate the target orientation. In different 20-trial mini-blocks the flankers will appear either lambda, 1.5 lambda, or 2 lambda from the target (i.e., closer or further from the target) and target contrast will be controlled by a 3/1 staircase separately for each spacing.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C6 - Training with Flankers (TWF)
Description: TWF will be reasonably different from the standard SPL task. Here, on 50% of trials a target Gabor will be presented at either 45° or 135° (as in SPL) and will be flanked by two collinear Gabors. On the remaining 50% of trials, flankers will be present without a target. TWF is thus a yes/no detection task, which is necessary since the collinear flankers fully indicate the target orientation. In different 20-trial mini-blocks the flankers will appear either lambda, 1.5 lambda, or 2 lambda from the target (i.e., closer or further from the target) and target contrast will be controlled by a 3/1 staircase separately for each spacing.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C7 - Parafoveal Training (PT)
Description: The PT condition is the baseline for C8-C11 (all of which involve parafoveally presented targets). In PT, we utilize the same task as in SPL, however, in PT, in addition to central training, targets will also appear in one of two peripheral locations (5° eccentricity; angles = 135° and 270°). The location of targets will be randomized trial-wise so as to discourage eye-movements and independent 3/1 staircases will be run at each location. By training only 2 peripheral locations we can measure the extent to which training gives rise to location transfer (e.g., in transfer tasks examining performance at 8 different locations - 2 trained locations and 6 untrained locations). Furthermore, training at the central location facilitates comparisons between PT and SPL.
Study NCT06084949 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nordic walking or inspiratory muscle training
Description: Nordic walking is a form of low-impact aerobic exercise that incorporates the use of walking poles. And inspiratory muscle training is a type of exercise that provides resistance during the inhalation phase.
Study NCT05830305 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mobile health intervention
Description: A protocol-based intervention via phone calls, which includes anti-hypertensive drug adjustment and reinforcement of lifestyle modification, will be implemented.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C7 - Parafoveal Training (PT)
Description: The PT condition is the baseline for C8-C11 (all of which involve parafoveally presented targets). In PT, we utilize the same task as in SPL, however, in PT, in addition to central training, targets will also appear in one of two peripheral locations (5° eccentricity; angles = 135° and 270°). The location of targets will be randomized trial-wise so as to discourage eye-movements and independent 3/1 staircases will be run at each location. By training only 2 peripheral locations we can measure the extent to which training gives rise to location transfer (e.g., in transfer tasks examining performance at 8 different locations - 2 trained locations and 6 untrained locations). Furthermore, training at the central location facilitates comparisons between PT and SPL.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C8 - Stimulus Variety (SV)
Description: The base task for SV is the PT condition. However, SV employ 20 trial mini-blocks of different SFs (.75, 1.5, 3, 6, 12, 24 cpd) and locations (45°, 135°, 225°, 315° - i.e., more locations than PT, but not the full set tested in the transfer battery) with separate staircases for each SF and location. Orientations will also be drawn from a larger set (22.5°, 45°, 67.5° - for which participants respond clockwise and 112.5°, 135°, 157.5° - for which participants respond counter-clockwise) and will vary on a trial-by-trial basis. This design holds-out 4 locations and 2 orientations to address transfer.
Study NCT05128955 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Splenic artery embolization with vascular embolic coils or plugs
Description: Splenic artery embolization with vascular embolic coils or plugs
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C8 - Stimulus Variety (SV)
Description: The base task for SV is the PT condition. However, SV employ 20 trial mini-blocks of different SFs (.75, 1.5, 3, 6, 12, 24 cpd) and locations (45°, 135°, 225°, 315° - i.e., more locations than PT, but not the full set tested in the transfer battery) with separate staircases for each SF and location. Orientations will also be drawn from a larger set (22.5°, 45°, 67.5° - for which participants respond clockwise and 112.5°, 135°, 157.5° - for which participants respond counter-clockwise) and will vary on a trial-by-trial basis. This design holds-out 4 locations and 2 orientations to address transfer.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C8a - Complex Features (CF)
Description: This is the same as C8, however we will use band-pass filtered stimuli similar to what has been done by a number of groups including Hussein et al.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C8a - Complex Features (CF)
Description: This is the same as C8, however we will use band-pass filtered stimuli similar to what has been done by a number of groups including Hussein et al.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C9 - Exogenous Attention Training (ExAT)
Description: Stimuli will be presented in a similar manner as in PT. However, in ExAT, a 100% valid cue, a small black dot - 48ms duration with an 96ms SOA prior to stimulus onset - will appear above the target location on each trial.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C9 - Exogenous Attention Training (ExAT)
Description: Stimuli will be presented in a similar manner as in PT. However, in ExAT, a 100% valid cue, a small black dot - 48ms duration with an 96ms SOA prior to stimulus onset - will appear above the target location on each trial.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C10 - Endogenous Attention Training (EnAT)
Description: Stimuli will be presented in a similar manner as in PT. However, in EnAT, a 100% valid cue (letter UL, LR; standing for upper left and lower right, respectively) - 150ms duration with an 500ms SOA prior to stimulus onset - will appear at the fixation point.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C10 - Endogenous Attention Training (EnAT)
Description: Stimuli will be presented in a similar manner as in PT. However, in EnAT, a 100% valid cue (letter UL, LR; standing for upper left and lower right, respectively) - 150ms duration with an 500ms SOA prior to stimulus onset - will appear at the fixation point.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: C11 - Multisensory Facilitation (MF)
Description: MF utilizes the same basic task structure as in ExEAT, however, rather than a visual cue, an auditory cue will be used (50ms, 1000hz tone with sound location determined by convolving sound with generic head-related transfer function, kemar large ears.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: C11 - Multisensory Facilitation (MF)
Description: MF utilizes the same basic task structure as in ExEAT, however, rather than a visual cue, an auditory cue will be used (50ms, 1000hz tone with sound location determined by convolving sound with generic head-related transfer function, kemar large ears.
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No Contact Control
Description: While not a training condition one type of experience that could be part of a condition is a no contact control (i.e., where participants do no training activities over the same rough time span as for the other training tasks).
Study NCT05894967 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: No Contact Control
Description: While not a training condition one type of experience that could be part of a condition is a no contact control (i.e., where participants do no training activities over the same rough time span as for the other training tasks).
Study NCT04336735 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: immunization app
Description: A transplant specific immunization app will be trialed that 1) provides vaccine information and education, 2) stores vaccine records and 3) provides reminders when vaccines are due
Study NCT06212648 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPC1001 High
Description: Drugs for clinical trials are orally administered once a day after breakfast.~After randomization, the drug for clinical trials is taken once a day (total of 4 tablets) for 8 weeks.
Study NCT06212648 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPC1001 Mid1
Description: Drugs for clinical trials are orally administered once a day after breakfast.~After randomization, the drug for clinical trials is taken once a day (total of 4 tablets) for 8 weeks.
Study NCT06212648 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPC1001 Mid2
Description: Drugs for clinical trials are orally administered once a day after breakfast.~After randomization, the drug for clinical trials is taken once a day (total of 4 tablets) for 8 weeks.