AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06489860 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoplasms
Description: Directions: For adults and for Children 1-12 years old. Indication: Malignant Neoplasms . Ingredient: Rice 90% and Honey 10% Powder (whole) 1g. Mix one packet with 6.8 fl oz (200 ml) of hot water (220ºF/100ºC) about three minutes until dissolved. Participants: Use 4 to 5 packets, use one pack each time after two hours.~Humidification: \<5%. Dosage Strength: 1.0 G/ 1 Unit, use one pack of 1 g for each time. Use within two years from the manufacturing date.
Study NCT05662891 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood Flow Restriction
Description: After randomization, a cuff was placed proximal to one lower extremity. Blood flow was restricted from 60% of the arterial occlusion pressure. The other extremity was determined as the control group. 3x5 nordic hamstring exercises were performed. Surface emg was measured for hamstring muscles during exercise.
Study NCT06501079 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
Description: ESP block will be performed U/S at the level of T 10 paraspinal level. The ultrasound transducer should be placed in the midline of the back at the desired level. The probe should then slowly be moved laterally until the transverse process is visible. The transverse process requires differentiation from the rib at that level.~Erector spinae muscle should be identified superficial to the transverse process. The needle inserted superior to the ultrasound probe in the cephalad to caudal direction. Once the needle tip is below the erector spinae muscle.~This separation from the transverse process confirms the proper needlemposition.~The local anesthetic should then be injected in 5 ml increments. The block will be performed preoperatively.
Study NCT06074380 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MIST surfactant
Description: Surfactant will be given via MIST while neonate is on CPAP
Study NCT06554132 — intervention group
Intervention type: OTHER
Intervention: Scleroderma Group
Description: Scleroderma patients will be evaluated in terms of respiratory muscle strength, aerobic capacity, pulmonary function test and fatigue.
Study NCT06554132 — intervention group
Intervention type: OTHER
Intervention: Healthy group
Description: Healthy people will be evaluated in terms of respiratory muscle strength, aerobic capacity, pulmonary function test and fatigue.
Study NCT04893980 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant human interleukin-2 (rhIL-2)
Description: During Day 0-14, patients in this group will receive treatment with antihistamines at the same dosage as pre-recruitment, together with a low-dose recombinant human Interleukin-2 (rhIL-2) at a dosage of 1 million international units every other day by intramuscular injection (rhIL-2, 1 MIU, im, Qod). During Day 15-28, the injections of rhIL-2 will be continued at the same dosage and the dose of antihistamines may be adjusted according to the control of symptoms.
Study NCT04893980 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Control group
Description: During Day 0-14, patients in the control group receive treatment with only antihistamines at the same dosage as pre-recruitment, but no injection of rhIL-2. During Day 15-28, treatment with low dose recombinant human Interleukin-2 (rhIL-2), i.e., 1 million international units every other day by subcutaneous or intramuscular injection (rhIL-2, 1MIU, im, Qod), will be added.
Study NCT04874571 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Muscle Energy Technique group
Description: In addition to the home exercise program of 12 sessions for 4 weeks, 3 days a week, muscle energy technique will be applied to the individuals in the MET(Musculer Energy Technique) group.
Study NCT04874571 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Energy Technique group
Description: In addition to the home exercise program of 12 sessions for 4 weeks, 3 days a week, muscle energy technique will be applied to the individuals in the MET(Musculer Energy Technique) group.
Study NCT05465811 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Program of physical exercises and health education by telerehabilitation
Description: To carry out the telerehabilitation program, the Google Meet platform will be used in order to provide the synchronous service model. This will occur for a period of 16 weeks, three weekly sessions lasting 50 minutes, (total of 48 sessions). The sessions will be given by physiotherapists and students in their final year of graduation in physiotherapy, which will consist of the following phases: initial rest, warm-up, resistance exercises, stretching exercises, relaxation and final rest.~In addition, in exchange for the warm-up phase, every 12 sessions, the telerehabilitation program also will have an approach through health education, using presentations, digital booklets and direct conversation between therapist and participants. The themes exhibited (importance of physical exercise in the pandemic context, reduction of the risk of falls through changes in the home environment and physiological changes resulting from aging) will intend to make them aware of better lifestyle habits.
Study NCT06175923 — intervention group
Intervention type: BIOLOGICAL
Intervention: Collection of EDTA (disodium salt of ethylenediaminetetraacetic acid) tubes of marrow during routine care
Description: When bone marrow is collected as part of a patient's care (diagnosis, follow-up, suspected AML/MDS hemopathy), one or two additional EDTA tubes of marrow are collected. Certain hematological data (NFP, genetic and molecular characteristics) will be collected in anonymized form and correlated with the BMP pathway alterations measured.
Study NCT06250270 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: protein or placebo
Description: casein protein (30g) or placebo (maltodextrin, 30g)
Study NCT06250270 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: protein or placebo
Description: casein protein (30g) or placebo (maltodextrin, 30g)
Study NCT06495307 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhPRG4
Description: Sterile isotonic aqueous solution containing rhPRG4 (450 µg/mL) for topical administration, 10 mM sodium phosphate, 150 mM sodium chloride \& 0.01% polysorbate 20 at pH 7.2. In all subjects, both eyes will be treated
Study NCT05466383 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Exercise rehabilitation with Schroth method
Study NCT05466383 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Brace
Description: Wear an orthopedic brace
Study NCT05580705 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Physical Therapy
Description: The Routine Physiotherapy treatment will include Transcutaneous Electrical Nerve Stimulation, Hot pack, Range of Motion (ROM) Exercises and Muscle Strengthening Exercises
Study NCT05580705 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vibration Therapy
Description: Vibration Therapy will include a vibration device of brand Manipol, model number RK-001. It has 360 degree off-centered axis with a frequency of 2500 times per minute. It will be applied on sole of the foot for about 15 mins.
Study NCT01280669 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravitreal injection 440mcg
Description: Intravitreal injections of sirolimus 440mcg/20mcL at baseline and months 1, 2, 3, 4, and 5.
Study NCT01280669 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravitreal injection of sirolimus 880mcg
Description: Intravitreal injection of 880mcg/20mcL sirolimus at baseline and months 2 and 4.
Study NCT05160389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PBI-200
Description: Single dose of PBI-200
Study NCT04781179 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CM-II
Description: It is an intervention of 4 two-hour sessions with a psychologist, MC-II technique
Study NCT04781179 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Psychoeducation
Description: It is an intervention of 4 two-hour sessions with a psychologist, psychoeducation
Study NCT05433142 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: XmAb819
Description: Monoclonal Bispecific Antibody
Study NCT05120804 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard behavioral treatment
Description: Nutrition and physical activity education along with behavior modification techniques
Study NCT05120804 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard behavioral treatment plus relationship skills training
Description: Nutrition and physical activity education along with behavior modification techniques plus relationship skills training
Study NCT06204783 — intervention group
Intervention type: OTHER
Intervention: Pressure volume (PV) loop measurement
Description: Pressure volume (PV) loop measurement using a conductance catheter
Study NCT06446388 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy drug
Description: Standard chemotherapy recommended by guidelines.
Study NCT04823507 — intervention group
Intervention type: DEVICE
Intervention: BIOFLEX DUO+
Description: * Data scores will be collected for patients who initially underwent the Workplace Post-Injury 1 test of the ImPACT® test system prior to PBM treatment.~* Patients were treated with photobiomodulation using the BIOFLEX® DUO+ system that utilized a 180 bulb Light Emitting Diode (LED) array followed by laser probes. Both delivery methods were applied to the cervical spine and the cranium, and both entailed the use of red light at 660 nm wavelength and near-infrared light at 830-840 nm wavelength. Treatment is provided three times per week on alternating days with weekends off for 4 weeks for a total of 12 treatments utilizing Health Canada approved device specific protocol guidelines for treatment of the cervical spine.~* Data scores will be collected for a second ImPACT® test using the Workplace Post-Injury 2 test.~* Results of the Post-Injury 1 test and the Post-Injury 2 test will be compared.
Study NCT06384794 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sperm capacitation through the ZyMōt®Sperm Separation Device®
Description: This chip based on microfluidic properties will help us to separate and recover the semen sample with improved sperm quality. It is composed of two microwells, one initial and one final, and a porous membrane through which the sample will be filtered and the capacitated spermatozoa with better motility will be selected. Syringe 850µL of the initial seminal sample into the first well and 750µL of seminal wash medium into the second well. The device is incubated at 37°C for up to 30 minutes. During this incubation, the sample will travel by microfluidic properties from the first well through the porous membrane to the second well. This membrane will filter those spermatozoa with a higher motility. Thus, at the end of the established incubation time, the medium with the selected spermatozoa from the second well (final well) will be collected with a syringe. After this, the sample will be processed and ready for the following procedures.
Study NCT06384794 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Swim-up
Description: The swim-up is a sperm capacitation technique in which the motile spermatozoa of the seminal sample, after centrifugation and incubation, move to the upper part of the medium. In this way, spermatozoa with good progressive motility will remain in the supernatant.
Study NCT06469619 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music listening
Description: Listening to music of one's choice one hour daily.
Study NCT03810573 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NB1
Description: rhNELL-1/DBX
Study NCT04877483 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: complete blood count (CBC)
Description: Group GB20 and Group GB20 plus BL2 will take the CBC(WBC、RBC、Hb、Platelet) analysis.
Study NCT04877483 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: complete blood count (CBC)
Description: Group GB20 and Group GB20 plus BL2 will take the CBC(WBC、RBC、Hb、Platelet) analysis.
Study NCT04877483 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: SF-36(36-Item Short Form Survey )
Description: Group GB20 and Group GB20 plus BL2 will take the SF-36 test.
Study NCT04931576 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: no drainage tube applied
Description: No drainage tube implacement after TOETVA
Study NCT05093621 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Furosemide
Description: Standard of care diuretic
Study NCT05093621 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Torsemide
Description: Standard of care diuretic
Study NCT06173375 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Cologuard
Description: Multi-target stool DNA test for colorectal cancer screening implemented by Exact Sciences. Cologuard has 94% sensitivity and 87% specificity to detect colorectal cancer.
Study NCT06173375 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Fecal Immunochemical Test
Description: Stool blood test for colorectal cancer screening. FIT has 75% sensitivity and 90% specificity to detect colorectal cancer.
Study NCT04877483 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: SF-36(36-Item Short Form Survey )
Description: Group GB20 and Group GB20 plus BL2 will take the SF-36 test.
Study NCT05084014 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep Stripping
Description: The deep longitudinal stripping can be applied on adhesions and knots in muscles. The lengthening stokes are parallel to muscle fiber and applied in an oblique direction with the help of the thumbs of hands/ elbow/ knuckles
Study NCT05084014 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kneading
Description: kneading lifts the muscle in circular movements with the help of the hands. It lifted, rolled, and squeezed muscle
Study NCT05397899 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abdominal hypopressive Exercises (AHE)
Description: Active and specific Therapeutic exercises will be used to treat postpartum low back pain in this study. AHE consisted of exhaling to their expiratory reserve volume, then holding their breath (apnea), and expanding their rib cage, to draw their abdominal wall inward and cranially without inhalation. Each exercise will have a specific frequency, intensity, and duration.
Study NCT05397899 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: General exercises
Description: General exercises are therapeutic exercises for core muscles for the treatment of postpartum low back pain.
Study NCT05757102 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FF/UMEC/VI
Description: FF/UMEC/VI will be administered.
Study NCT05757102 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ELLIPTA
Description: FF/UMEC/VI and FF/VI will be administered via ELLIPTA inhaler
Study NCT05757102 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ELLIPTA
Description: FF/UMEC/VI and FF/VI will be administered via ELLIPTA inhaler
Study NCT05757102 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FF/VI
Description: FF/VI will be administered.
Study NCT04781023 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Colpofix
Description: Intravaginal gel with carboxymtheyl beta-glucan and polycabophil. Posology: 1 application / day x 20 days, rest 10. Repeat 20 x 3 cycles
Study NCT01296217 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: lymph nod detection
Study NCT05145595 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thermal Sensory Analyzer
Description: Thermal stimuli: The Thermal Sensory Analyzer (TSA-II or PATHWAY platform - Medoc, Ramat Yishai, Israel) will be used to deliver heat and cold stimuli. These devices can deliver relatively complex stimuli via computer control. All targeted stimulus temperatures will be less than 50°C, and participants will be free to remove their arm or leg at any time from the thermode. Noxious cold stimuli will also be delivered with a plastic water container or a water bath (FISHER, USA). Participants will be free to pull out of the water bath at any time.
Study NCT05145595 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pressure Stimuli
Description: Pressure stimuli: Pressure stimuli will be applied by using a handheld algometer (Wagner Instruments) or the Pressure Algometer (Medoc, Ramat Yishai, Israel). These devices have a round probe that allows quantifying the amount of pressure that is being applied. The Pressure Algometer allows a real-time visual feedback to control and monitor applied pressure rates. Pressure will be applied to the lower leg, volar forearm, or trapezius.
Study NCT05145595 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical Stimuli
Description: Mechanical stimuli: A set of standardised von Frey filaments (0.25, 0.5, 1, 2, 4, 8, 16, 32, 64, 128 and 256mN). The contact area of the hairs with the skin is of uniform size (\<1 mm²) and texture.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pain Ratings
Description: Pain intensity and pain unpleasantness ratings will be assessed by numerical rating scale (ranging from 0- no pain/unpleasantness to- 100 the most intense/unpleasantness pain imaginable) and by mechanical and computerized visual analog scales (VAS which ranges between ''no pain sensation'' and ''most intense pain imaginable'').
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Thermal pain thresholds
Description: Cold and heat pain thresholds (CPT and HPT, respectively) will be determined \[22; 55\]. Thresholds are determined by continuous ramping of temperature from 32°C baseline temperature until the participant press a button at the first moment he/she feels pain from the stimulus. Cut-off temperatures are 0°C and 50°C, to minimize potential damage to the skin. The baseline temperature to which the thermode returns before each test is 32°C. The first threshold measurement will be used as a familiarization. The average threshold is calculated from three measurements.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pressure pain thresholds (PPT)
Description: Pressure will be increased continually and participants will be instructed to press a button the first moment they feel pain from the pressure stimulus. The first threshold measurement will be used as a familiarization. The average threshold is calculated from three measurements.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mechanical temporal summation
Description: A pinprick stimulus with standardised intensity (#6.10 or #6.45 von Frey filament) and a flat contact area of 0.25mm diameter will be used. In this test, participants will rate the pain evoked by a single pinprick stimulus and by a series of 10 identical pinprick stimuli. The 10 identical pinprick stimuli are applied with a frequency of 1 s-1 within an area of 1 cm2. Immediately following the single stimulus and series of stimuli, an evaluation of the pain will be collected. The difference in pain ratings evoked with the one stimuli vs. the 10 stimuli is the temporal summation value.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conditioned pain modulation (CPM) efficiency
Description: The CPM paradigm assesses endogenous inhibitory pain modulation efficiency related to spatial filtering of nociceptive information. CPM testing includes the application of a test stimulus without conditioning (control run) and a subsequent application of the same test stimulus together with a conditioning stimulus (conditioning run). Heat-CPM and pressure-CPM. Heat and pressure CPM will be tested in random order.~The difference between the pain ratings/thresholds of the test stimulus with vs. without the concomitant conditioning stimulus is the CPM magnitude. CPM\<0 (reduction in pain) implies efficient inhibitory pain modulation of spatial filtering.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Offset analgesia efficiency
Description: Offset analgesia (OA) paradigm assesses endogenous inhibitory pain modulation efficiency of temporal filtering of nociceptive information. The mechanisms underlying OA are distinct from the CPM mechanisms \[41\]. OA is characterized by a disproportionately large reduction in pain perception after a small decrease in temperature during noxious thermal stimulation.~Offset analgesia will be assessed using the three-temperature method (T1°C 5s, T1+1°C 5s, T1°C 20s). The T1 will be noxious heat (44-48°C) delivered to the hand or leg. During the OA paradigm, real time pain intensity ratings will be obtained using the computerized VAS.~The difference between the pain ratings of the 10-20 seconds noxious stimulus in the OA paradigm compared to a control paradigm (30 seconds of T1) is the OA magnitude. OA\<0 (reduction in pain) implies efficient inhibitory pain modulation of temporal filtering.
Study NCT05145595 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cold pain tolerance
Description: Cold pain tolerance will be assessed by having participants immerse their hand or foot in a cold (4-12°C) water bath. Tolerance will be defined by the time of hand withdrawal. VAS ratings of cold pain intensity might be obtained periodically, and both pain intensity and pain unpleasantness will be recorded upon hand withdrawal. Limb immersion in the cold water bath will be terminated after 120 s if participants do not withdraw their hand before then.
Study NCT05085730 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InMode Morpheus8 System
Description: The InMode Morpheus8 System is a bipolar fractional radiofrequency device which uses microneedles and thermal heat to stimulate neocollagenesis and neoelastogenesis.