AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06195930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vericiguat (BAY1021189) 5 mg
Description: Vericiguat (BAY1021189) will be taken as 5 mg tablet 1x daily over at least 14 days up to 18 days (+ 4 days time window allowed)
Study NCT06151093 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-based games intervention
Description: These games are applied via using Nintendo Wii~1st - 2nd Week Applications~* Basic Step~* Penguin slide (right-left weight transfer)~* Snowball flight (right-left weight transfer)~* Tilt city (right-left weight transfer)~  3rd-4th Week Applications~* Advanced Step~* Snowball flight (right-left weight transfer)~* Penguin slide (right-left weight transfer)~* Table tilt (weight transfer in 4 directions)~  5th-6th Week Applications~* Advanced Step~* Table tilt (weight transfer in 4 directions)~* Balance bubble (weight transfer to 4 directions)~* Ski slalom (weight transfer in 4 directions)
Study NCT06151093 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Balance exercises
Description: 1st-2nd Week Applications On a flat-hard surface;~* Standing on 2 legs~* Stepping forward and backward (separately for both feet)~* Getting into the tandem position and maintaining the position (separately for both feet)~* Standing on one leg (separately for both feet)~* Weight transfer in four directions~* Taking a step back towards the step~* Stepping on the stability ball~  3rd-4th Week Applications All exercises which applied in 1st and 2nd week are applied on mat.~  5th-6th Week Applications On the balance board;~* Standing on 2 legs~* Stepping forward and backward (separately for both feet)~* Getting into the tandem position and maintaining the position (separately for both feet)~* Standing on one leg (separately for both feet)~* Weight transfer in four directions~* Catching balls thrown by the enforcer
Study NCT06339853 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WELT-IP with wearable devices (Apple/galaxy watch. Oura ring)
Description: WELT-IP (an investigational digital therapeutic) is an CBT-I based intervention designed to treat insomnia, conducted in 6 sessions. It is a comprehensive program delivering sleep restriction, stimulation control, muscle relaxation, cognitive treatment, and sleep hygiene education. Main features are sleep diary, sleep reports, daily lessons of CBT-I, muscle relaxation techniques, and cognitive intervention through chatbot. By using WELT-IP simultaneously with wearing an Apple Watch/Galaxy Watch and Oura Ring, sleep and environmental data can be collected.
Study NCT05447065 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D supplement
Description: Only the experimental group (D) received the vitamin D supplement.
Study NCT06228716 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Training with hybrid simulation method
Description: Subcutaneous biological drug self-administration training was given by the researcher in two stages, theoretical and practical, face to face. Power point presentation and training brochure were used in theoretical training. The practical training given after the theoretical training was given using the Hybrid simulation method. The Wearable Subcutaneous Injection Hybrid Simulator developed by the researcher was worn by the individuals after being informed about its purpose and function. Afterwards, they were expected to apply the subcutaneous application step by step as explained to them. Each application step they made incorrectly was corrected and repeated with the support of the researcher. The application was considered successful if they completed all application steps correctly from start to finish. The training took approximately 40 minutes. After the practical training, the individuals' questions, if any, were answered and the training was terminated.
Study NCT06215235 — intervention group
Intervention type: OTHER
Intervention: Bright light therapy
Description: for 2 weeks the patient will take place for a 10.000lux lamp for 20-30 minutes.
Study NCT04801251 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Echocardiographic examination
Description: Each patient included will undergo full cardiac physical examination and echocardiographic examination
Study NCT05681117 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: multi-component nutrition education
Description: Classroom-based nutrition education 40 minutes once a week for 4 weeks~SMS Reminders SMS reminders containing healthy nutrition tips 2 times a week, 1 weekday, 1 weekend, starting with nutrition education and throughout the education (4 weeks)~Brochure Distribution Brochures prepared in accordance with the content of classroom-based nutrition education were distributed immediately after the nutrition education.~Controversial Supermarket Tour Nutrition label reading activity aimed at gaining the ability to evaluate product contents, in line with the information explained in module 4, in the supermarket tour planned to be organized once with an appropriate number of student groups (maximum 7 people) after the nutrition education
Study NCT05444699 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone Sodium Phosphate
Description: Oral suspension administered 1 mg/kg once a day for three days
Study NCT05444699 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sugar syrup
Description: Oral suspension administered the same amount in milliliters as experimental product once a day for three days
Study NCT05660629 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan Mobilization
Description: Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.
Study NCT05660629 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mulligan Mobilization
Description: Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.
Study NCT04767464 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Compass Course
Description: The Compass Course is an 8-session group course designed to address purpose in life of those with Breast Cancer. Enrollment in this arm will involve participation in the Compass Course virtually.
Study NCT05551390 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: one-time umbilical cord milking
Description: Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision.~Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.
Study NCT05551390 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: three-times umbilical cord milking
Description: Before UCM procedures, in the case of vaginal delivery, the maternity doctor or nurse held the newborn below the level of the introitus. In the case of a cesarean section, the surgeon carries the newborn below the level of the incision.~Then maternity nurse or doctor swiped blood in length 20 centimeters of umbilical cord into the newborn, according to the number of swipes that assigned, then cutting the umbilical cord by the international standard methods. Newborns after birth were cared for and assessed according to the newborn nursing standards of QSMH in the department of pediatrics.
Study NCT06139926 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine administered intranasally
Description: Intranasal administration of dexmedetomidine (plain) was given at the bedside of the ward as per the pre-tested recommended dose. The patient's vital signs were maintained. On the day of surgery, 30 min before induction of anesthesia, intranasal dexmedetomidine (original solution) was administered in the operating room at the pre-tested recommended dose.
Study NCT06139926 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Dexmedetomidine administered intranasally
Description: Intranasal administration of dexmedetomidine (plain) was given at the bedside of the ward as per the pre-tested recommended dose. The patient's vital signs were maintained. On the day of surgery, 30 min before induction of anesthesia, intranasal dexmedetomidine (original solution) was administered in the operating room at the pre-tested recommended dose.
Study NCT06613022 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instrument Assisted Soft Tissue Mobilization first Control second
Description: Instrument assisted soft tissue mobilization was utilized first on day one and wait-control was completed on second day.
Study NCT06613022 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control first Instrument Assisted Soft Tissue Mobilization second
Description: This intervention involved waiting for 20 minutes between pre-test and post-test on day one and having Instrument Assisted Soft Tissue Mobilization on day two.
Study NCT05117060 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LEO 152020 tablet
Description: LEO 152020 is a small drug molecule which can bind to the histamine 4 receptor (H4R) and prevent histamine from binding to the receptor. LEO 152020 is a tablet for oral administration.
Study NCT05117060 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: LEO 152020 placebo tablet
Description: LEO 152020 placebo tablet contains the same excipients in the same concentration as LEO 152020 tablet, except that it does not contain the medical ingredient LEO 152020. LEO 152020 placebo is a tablet for oral administration.
Study NCT05117060 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LEO 152020 placebo tablet
Description: LEO 152020 placebo tablet contains the same excipients in the same concentration as LEO 152020 tablet, except that it does not contain the medical ingredient LEO 152020. LEO 152020 placebo is a tablet for oral administration.
Study NCT04703985 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: Enteral Nutrition
Description: Protocol of Enteral Nutrition adapted to the conditioning autograft (BEAM or Melphalan 200)
Study NCT06228716 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Broshure
Description: Subcutaneous biological drug self-administration training was given theoretically face to face by the researcher using a power point presentation and training brochure. The training lasted approximately 25 minutes and was given in the same room where the experimental group received training. After the training, any questions the individuals had were answered and the training was ended.
Study NCT06439108 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: single symphyseal plating in management of vertically unsable open book pelvic ring injuries
Description: open book pelvic ring injuries can be managed via the two techniques.
Study NCT06428266 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bicanalicular intubation
Description: Placement of the bicanalicular intubation set at each lacrimal point and fixed by means of its flaps at the level of the opening of the lacrimal sac.
Study NCT06428266 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Closed dacryointubation
Description: Placement of dacryointubation tube through the canaliculus until it reaches the medial wall of the lacrimal sac and then passed the nasolacrimal duct until it empties out at the level of the inferior meatus.
Study NCT05757817 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Oropharyngeal or oral cavity reconstruction
Description: Oropharyngeal or oral cavity reconstruction will be performed using a free super thin external pudendal artery flap (STEPA flap).~Post-operative follow-up and adjuvant treatment: Post-operative follow-up of patients will be performed according to the standards of the participating centers.
Study NCT06425796 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Adiposity and Iron Requirements in Pregnancy (ADIPREG)
Description: Iron 25 arm will receive: two iron supplements containing 12.5 mg of elemental iron + 1 multivitamin supplement (they will receive a total of 3 supplements per day).~Iron 50 arm will receive: two 25 mg elemental iron supplements + 1 multivitamin supplement (they will receive a total of 3 supplements per day).~The multivitamin supplement will contain folic acid, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin C and vitamin D. In summary, each participant will receive 3 supplements per day and instructed to take the 3 supplements together, in the morning, with breakfast. Supplements will be given to the participants when they attend for their clinic appointment. The intervention will begin at 12 gestational weeks and continue until the baby is delivered.
Study NCT05702580 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Agitated Pleural Fluid Thoracentesis
Description: Using a 16-18 gauge cannula, a standard thoracentesis will be performed then a sample of pleural fluid will be aspirated and rapidly flushed into the pleural space and redrawn again for a few cycles before a sample is finally drawn into the collection syringe
Study NCT05332041 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Predicta Bioactive bulk fil composite restoration
Description: Predicta Bioactive bulk fil resin composite restoration material
Study NCT05332041 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Predicta Bioactive bulk fil composite restoration
Description: Predicta Bioactive bulk fil resin composite restoration material
Study NCT05646927 — intervention group
Intervention type: PROCEDURE
Intervention: Selection of parent(mother or father) according to children preference
Description: The parent who will accompany the child during the perioperative period will be determined by children preference
Study NCT05646927 — intervention group
Intervention type: PROCEDURE
Intervention: Selection of parent(mother or father) according to randomization
Description: The parent who will accompany the child during the perioperative period will be determined by randomization.
Study NCT05380557 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Germline genetic testing
Description: Germline genetic testing will be provided to each patient
Study NCT05861245 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: 5-fraction hipofractionated protontheray
Description: The therapeutic schemes that will be proposed to patients based on clinical criteria such as tumor size and relationship of the tumor with adjacent critical organs are:~* For chordomas: 37.5 Gy in 5 consecutive sessions of 7.5 Gy per fraction.~* For chondrosarcomas: 35 Gy in 5 consecutive sessions of 7 Gy per fraction.
Study NCT06258434 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: multiomics Colorectal Cancer (CRC) screening test (CRC-Appareo)
Description: Patients who are at high risk of developing CRC or confirmed CRC and willing to conduct colonoscopy examination will be asked to collect blood prior to bowl preparation for multiomics CRC screening test which using Reduced Representation Bisulfite Sequencing (RRBS) technology to obtain multidimensional variation information on cell-free DNA (cfDNA) methylation, end sequence, fragment size distribution, and copy number variation in the blood, and integrate analysis through machine learning algorithms to accurately assess the risk of colorectal cancer and advanced adenoma. and will be asked to collect stool sample for commercially available FIT assay. Colonoscopy and histopathologic examination are used as reference. The diagnosis information of each sample was blind to the participants who conduct the multiomics profiling, as well as the informatics who perform the integrate analysis.
Study NCT06118905 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Denosumab 60 MG/ML
Description: Subjects to receive Denosumab 60mg SQ and Zoledronic acid placebo IV
Study NCT06118905 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zoledronic Acid 5Mg/Bag 100Ml Infusion
Description: Subjects to receive Zoledronic Acid 5mg IV and Denosumab placebo
Study NCT05440253 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dry needling
Description: Dry needling of the trigger point of the gluteus medius in patients diagnosed with non-specific low back pain.
Study NCT05440253 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ischemic compression
Description: Ischaemic trigger point compression of the gluteus medius in patients diagnosed with non-specific low back pain.
Study NCT05127564 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diroximel fumarate
Description: Administered as specified in the treatment arm
Study NCT05862428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rectal misoprostol
Description: This intervention group receive Misoprostol transrectally before undergoing total abdominal hysterectomy
Study NCT06219863 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Body weight supported harness
Description: A body weight supported harness will be provided to families for one month to set up in their home. Caregivers will be asked to use the harness for their infants for 30 min per day, 5 days a week. Caregivers will complete a daily log describing harness use. At the end of the month, they will complete feasibility and acceptability questionnaires.
Study NCT05097196 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate-intensity aerobic activities
Description: The exercise intensity of the individual is planned at 50-60% heart rate reserve using the Karvonen method.
Study NCT05240326 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercise training group
Description: All exercise program will be applied during supervised session by a physiotherapist. Clinical pilates exercises will be performed three days in a week. Treatment will continue an hour in per session for 8 weeks. The program consisted of 10 minutes warm-up exercises, clinical pilates-based exercises on mat for 40 minutes and 10 minutes relaxation and stretching exercises.
Study NCT05240326 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: control training group
Description: The control group will be followed up as a home program by giving the relaxation exercises. Patients will be asked to do the exercises regularly for 3 days/week, 1 sessions/day, for eight weeks. Patients in the control group will be followed up by phone once a week.
Study NCT05648929 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Patient Satisfaction Questionnaire
Description: During regular clinical examinations patient will go through a short questionnaire at week 4, 16 and 24 to check patient satisfaction with expanders
Study NCT05648929 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Pregnancy test
Description: Pre-op; to sufficiently check pregnancy as exclusion criteria
Study NCT05648929 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Blood draw
Description: pre- expander implantation, alongside anaesthesia pre- expander explantation and exchange with definite implant alongside anaesthesia - no additional vein irritation needed
Study NCT05648929 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Expander based breast reconstruction
Description: implantation of 2 different expanders intraindividually
Study NCT05648929 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound of breast
Description: Measurement of capsular thickness pre- expander removal
Study NCT05648929 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: S(AE )monitoring
Description: (S)AE evaluation will be performed from Visit 1 (Day 0 = Expander implantation) to Visit 15 (Day 168-196 = Reoperation) according to visit plan.
Study NCT05252442 — intervention group
Intervention type: OTHER
Intervention: Pre-COVID-19
Description: Pre-COVID-19 period
Study NCT05252442 — intervention group
Intervention type: OTHER
Intervention: COVID-19
Description: COVID-19 period
Study NCT05252442 — intervention group
Intervention type: OTHER
Intervention: COVID-19 vaccination roll-out
Description: COVID-19 vaccination roll-out period
Study NCT05884177 — intervention group
Intervention type: OTHER
Intervention: Short-term cold exposure
Description: Short-term cold exposure
Study NCT06225505 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: ctDNA monitoring
Description: For each patient included, a ctDNA detection assay will be performed in blood samples every 3 months, while extra-plasma will be banked. ctDNA results will be available with a turnaround time of less than 3 weeks. When negative, ctDNA detection results will not be disclosed to patients nor clinicians.
Study NCT06225505 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ctDNA monitoring
Description: For each patient included, a ctDNA detection assay will be performed in blood samples every 3 months, while extra-plasma will be banked. ctDNA results will be available with a turnaround time of less than 3 weeks. When negative, ctDNA detection results will not be disclosed to patients nor clinicians.
Study NCT06225505 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: 68Ga-FAPI-46-PET-CT
Description: ). To locate metastatic deposits, patients will be offered to undergo a whole-body imaging with 18F-FDG PET-CT and 68Ga-FAPI-46-PET-CT, in addition to any other workup considered as relevant by their treating physician.
Study NCT06225505 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46-PET-CT
Description: ). To locate metastatic deposits, patients will be offered to undergo a whole-body imaging with 18F-FDG PET-CT and 68Ga-FAPI-46-PET-CT, in addition to any other workup considered as relevant by their treating physician.
Study NCT04863482 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: IOC
Description: intra-operative cholangiography near-infrared fluorescence cholangiography