AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06071468 — intervention group
Intervention type: PROCEDURE
Intervention: Endocscopic CTR
Description: Endoscopic CTR makes one or two short incisions to introduce instruments for visualizing. The key procedural steps involved in Endoscopic CTR are listed below.~1. Following the delivery of anesthesia, the surgeon makes a small wrist incision (usually less than 1.5 cm), with or without a small palmar incision (usually less than 1.5 cm, depending on whether they are using a single portal or double portal technique, respectively.~2. A series of dilators and raspers are used to create space in the carpal tunnel and clear synovial tissue from the undersurface fo the TCL.~3. A camera attached to a narrow tube (endoscope) is inserted into the carpal tunnel.~4. The transverse carpal ligament (which forms the roof of the carpal tunnel) is identified.~5. Using specialized cutting instruments and endoscopic guidance, the surgeon transects the TCL.~6. Endoscopic visualization and/or probing are used to confirm a complete release.~7. The wound(s) is/are typically closed with sutures.
Study NCT06071468 — intervention group
Intervention type: PROCEDURE
Intervention: Open CTR
Description: OCTR is the most commonly used CTR technique in the United States.The key procedural steps involved in OCTR are listed below.~1. Following the delivery of anesthesia, an incision is made in the palm directly over the carpal tunnel.~2. The surgeon cuts through the palmar fascia to identify the TCL.~3. The surgeon transects the TCL with a scalpel and/or similar cutting instruments.~4. The surgeon inspects the carpal tunnel to ensure proper decompression.~5. The wound is closed with sutures.
Study NCT06089473 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Intervention Group: Exercise and education.
Description: * Exercise Intervention: 12-weeks of supervised, individualized virtual exercise sessions, delivered by an accredited kinesiologist. Independent unsupervised sessions start at week 5. After 12 weeks, a 5-month maintenance phase is followed, continuing to exercise three times weekly for 30 minutes per session.~* Education: Prior to each zoom session with the kinesiologist (starting on week 2), participants will watch short educational videos. Additionally, participants will be provided a document (PDF) of evidence-based strategies to help cope with stress.
Study NCT06089473 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care Only
Description: Usual Care for kidney transplant candidates, which may include medical visits, nutrition, and psychological support.
Study NCT06089291 — intervention group
Intervention type: DEVICE
Intervention: Persona IQ
Description: Persona IQ is a system comprised of the following subsystems:~1. RTM utilizing mymobility® patient application and care team dashboard,~2. PPK System with~3. CTE Extension Implant and Instrumentation,~   1. Surgical Base Station System,~  2. Home Base Station System,~  3. Canary CDMP,~  4. Canary CMGP software module, and~4. The ZBEdgeTM Connected Artificial Intelligence data platform.~The system combines physical components, electronics, software, and user interfaces to collect, store, analyze, transmit, and display patient data for use by both physicians and patients.
Study NCT05738096 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TSEP + rhizotomy surgery
Description: TGN patients recruited for this study will already be undergoing percutaneous rhizotomy surgery. TSEPs will be measured at baseline prior to surgery. During the rhizotomy procedure, an electrode or balloon is placed through a metal sheath to then damage the nerve. A stylet is introduced to clear tissue from the sheath in preparation for the electrode or balloon. Prior to the final insertion of the RF electrode where the gasserian ganglion will be damaged, we will place a standard stereotactic EEG electrode (SEEG). Following damaging the nerve (clinical procedure), we will record again to measure differences in the TSEPs following cell body damage. The Neuralynx system will be used to record the potentials at 40 KHz.
Study NCT06662357 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral Treatment
Description: Family Connections Care Planning Team: Clinical expertise will be combined with peer-to-peer parent/guardian support for trauma-informed care delivery to both parent and child. All aspects of the care continuum will be provided in a culturally and linguistically competent manner, with child and family-driven care planning.
Study NCT06248515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab govitecan-hziy
Description: 10 mg/kg once weekly on Days 1 and 8 of continuous 21-day treatment cycles
Study NCT06542380 — intervention group
Intervention type: DEVICE
Intervention: TAVI, pacemaker
Description: Retrospective analysis of need for pacemaker implantation after TAVI
Study NCT06668155 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Autograft Group
Description: If assigned the autograft group, the surgeon will choose either bone patella tendon bone (BPTB) or all soft tissue quadriceps tendon for the graft. The graft choice will be based upon surgeon preference.
Study NCT06668155 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Allograft with LET Group
Description: The allograft used will be a non-irradiated quadriceps tendon with bone plug allograft with a donor age less than 45 years.
Study NCT05339425 — intervention group
Intervention type: OTHER
Intervention: No additional intervention will be administered.
Description: No additional intervention will be administered.
Study NCT06569641 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neoneur Feeding System
Description: The Neoneur Feeding System is placed between a nipple and a bottle, and used to measure feeding skill patterns.
Study NCT05053113 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Activity Monitor
Description: Monitor physical activity with FitBit
Study NCT05053113 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Activity Monitor
Description: Monitor physical activity with FitBit
Study NCT05053113 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Activity Monitor
Description: Wear accelerometer
Study NCT05053113 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Activity Monitor
Description: Wear accelerometer
Study NCT05053113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Receive educational newsletter
Study NCT05053113 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Educational Intervention
Description: Receive educational newsletter
Study NCT05053113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT05053113 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Ancillary studies
Study NCT05053113 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telephone-Based Intervention
Description: Receive phone call from health coach
Study NCT05053113 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Telephone-Based Intervention
Description: Receive phone call from health coach
Study NCT06569628 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Envita Stories Methodology in Long-term care Centres for old adults
Description: Collaborative intervention program in long-term care Centres for old adults between professionals, old adults, families and volunteers that aims to foster person-centered care and promote meaningful relationships through the digitization of life stories and life project methodologies in a timeline.
Study NCT06602102 — intervention group
Intervention type: DEVICE
Intervention: Mixed reality Glasses
Description: Mixed reality glasses are devices that combine elements of augmented reality and virtual reality. They allow users to overlay digital images onto the real world, enabling interaction with virtual objects in a physical environment. These glasses typically use sensors, cameras, and tracking technology to map the surroundings and provide an immersive experience. They are used in various applications, such as gaming, education, design, and professional training.
Study NCT06679348 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: walking exercise on treadmill
Description: The study included two intervention groups, consisting of participants who met the inclusion criteria and adhered to the experimental procedures. One group will do treadmill walking exercises, while the other will do treadmill walking exercises using virtual reality (VR). Both interventions were conducted in a single session, with each group participating in a 20-minute walking exercise session at a moderate intensity, as identified by other studies.
Study NCT06679348 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treadmill walking exercise using VR
Description: Walking on the treadmill with the Free Run game on the Nintendo Wii allows users to walk at 5 miles per hour for 20 minutes. The user gets on the Wii Balance Board and starts walking in the virtual environment after running the application. The application detects the user's movements and controls the progress of the virtual character. During this experience, users increase their motivation by encountering various landscapes while tracking their performance and getting information about the calories they spend. This setup provides a fun, game-like atmosphere for a realistic walking experience.
Study NCT06618287 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986507
Description: Specified dose on specified days
Study NCT06618287 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: Specified dose on specified days
Study NCT06618287 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Specified dose on specified days
Study NCT05590624 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lower-Carbohydrate Med-t-Diet
Description: Diet will focus on including:~* Lean protein sources~* High-quality fat~* High-quality carbohydrate sources that are rich in fiber~* Nuts and seeds~Diet will focus on limiting:~* Refined sugars~* High glycemic carbohydrates~* Seed oils that may cause inflammation~Diet Composition: 45% fats, 35% carbs, 20% protein
Study NCT05590624 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-Fat Med-t-Diet
Description: Diet will focus on including:~* Lean protein sources~* High-quality fat~* High-quality carbohydrate sources that are rich in fiber~* Nuts and seeds~Diet will focus on limiting:~* Refined sugars~* High glycemic carbohydrates~* Seed oils that may cause inflammation~Diet Composition: 70% carbs, 20% protein, 10% fat
Study NCT06679842 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ascitis paracentesis
Description: ascitis paracentesis
Study NCT05970731 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Beclomethasone
Description: 84 mcg of Beclomethasone administered topically on an intranasal microsponge, placed in the olfactory cleft using a nasal endoscope, on day 1 and repeated on day 14.
Study NCT06569628 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contact Methodology in Long-term Care Centres for old adults
Description: Professionals know and use Envita Stories Methodology but do not apply it directly with these people.
Study NCT05211960 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based meditation
Description: AmDTx is a mindfulness-based meditation app that includes lessons, interactive exercises, and additional in-app features to practice mindfulness.
Study NCT05226338 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: D-0502
Description: Formulation 1 Formulation 2 Formulation 3
Study NCT05970731 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (0.9% sodium chloride) administered topically on an intranasal microsponge, placed in the olfactory cleft using a nasal endoscope, on day 1 and repeated on day 14.
Study NCT06455631 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Facilitated Tucking, Oral Breast Milk , Kangaroo Care
Description: Before data collection, the researcher will inform families of newborns meeting the sample criteria about the study and obtain written consent from participating parents. Newborn and parent information will be recorded. Procedures will occur between 08:00 and 16:00, with one researcher, two nurses, and a preterm newborn present during tape removal. Tape removal will be done by the same nurse. Physiological and behavioral responses will be recorded before, during, and after tape removal. Breast milk will be orally administered during tape removal, with the amount adjusted based on gestational age. Measurements will be taken at specified time points, including heart rate, respiratory rate, oxygen saturation, and PIPP-R score. These procedures will also apply to the control group. PIPP-R scores will be recorded by two evaluators based on video recordings.
Study NCT06475495 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KYV101
Description: an autologous fully-human anti-CD19 CAR T-cell immunotherapy
Study NCT06475495 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab (active comparator)
Description: anti CD20 monoclonal antibody
Study NCT06682169 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rovadicitinib
Description: Rovadicitinib is an inhibitor of Janus associated kinases (JAK) family and Rho associated kinases (ROCK). It can inhibit the sustained abnormal activation of the Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway and also inhibit Rho associated kinase 2 (ROCK2). The JAK 1-JAK 2 signaling pathway is a key step in causing inflammation and tissue damage in acute and chronic graft-versus-host disease.
Study NCT06682169 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Imatinib
Description: Imatinib tyrosine kinase inhibitor is a small molecule protein kinase inhibitor that has the ability to block one or more protein kinases. Clinically used for the treatment of chronic myeloid leukemia and malignant gastrointestinal stromal tumors.
Study NCT06682169 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate
Description: Methotrexate is an organic compound, mainly used as an anti folate anti-tumor drug. It inhibits the synthesis of tumor cells by inhibiting dihydrofolate reductase, thereby inhibiting the growth and reproduction of tumor cells.
Study NCT04077320 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory Self-Efficacy Training
Description: The intervention will consist of a six-week cognitive behavioral intervention integrating the four pillars of self-efficacy, Mastery, Social Modeling, Coaching, and Physiological Responses (West et al. 2008). Each week will comprise of a 1.5 hour session which focuses on an educational component, discussions and active learning practice activities to apply lesson material. Additionally, participants will be given take home exercises to practice outside a classroom setting. The sessions will be conducted in small groups of 4-6 people.
Study NCT04077320 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General Education
Description: The active control intervention will be a general education class consisting of real world knowledge and factual information on various topics unrelated to memory. This intervention will follow the same format as the memory self-efficacy training arm. One 1.5 hours session every week for 6 weeks, in small groups.
Study NCT06682169 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mycophenolate mofetil
Description: Metoprolol ester is an organic compound mainly used as an immunosuppressant
Study NCT06682169 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Rituximab activates antibody dependent cell-mediated phagocytosis and complement dependent cytotoxicity by binding to cluster of differentiation 20 (CD20) antigen, clearing malignant B cells expressing CD20 and achieving therapeutic goals.
Study NCT05554731 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a New Balloon Catheter for Intraairway Hemostasis
Description: In the treatment group, the new balloon catheter was inserted in three steps, that is, the tracheoscope was inserted into the airway to remove the blood in the airway and find the target bronchus.The new airway hemostatic balloon catheter was directly inserted through the tracheoscopy biopsy channel, and then directly inflated and fixed after positioning.Then exit the tracheoscope directly to complete.
Study NCT05554731 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: a New Balloon Catheter for Intraairway Hemostasis
Description: In the treatment group, the new balloon catheter was inserted in three steps, that is, the tracheoscope was inserted into the airway to remove the blood in the airway and find the target bronchus.The new airway hemostatic balloon catheter was directly inserted through the tracheoscopy biopsy channel, and then directly inflated and fixed after positioning.Then exit the tracheoscope directly to complete.
Study NCT05554731 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Traditional Therapy
Description: A six-step technique was adopted to place the traditional balloon catheter, that is, the tracheoscope was entered to find the target bronchus, the guide wire was inserted through the biopsy channel, the tracheoscope was exchanged to exit the tracheoscope, the catheter was entered through the guide wire exchange, the tracheoscope was re-entered, the catheter was positioned, inflated and fixed, and the tracheoscope was withdrawn.
Study NCT05554731 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Therapy
Description: A six-step technique was adopted to place the traditional balloon catheter, that is, the tracheoscope was entered to find the target bronchus, the guide wire was inserted through the biopsy channel, the tracheoscope was exchanged to exit the tracheoscope, the catheter was entered through the guide wire exchange, the tracheoscope was re-entered, the catheter was positioned, inflated and fixed, and the tracheoscope was withdrawn.
Study NCT06631079 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NECVAX-NEO1
Description: Bacteria-based orally administered personalised neoantigen-targeting cancer vaccine
Study NCT05970731 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Microsponge
Description: Drug delivery using chitosan-based biocompatible microsponge
Study NCT05970731 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Microsponge
Description: Drug delivery using chitosan-based biocompatible microsponge
Study NCT06041997 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone restriction
Description: The patients will then be advised to cut down the usage by one-third in terms of usage hours. The compliance will be checked at the time of outcome assessment.
Study NCT05787652 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ARTEMIS mobile app
Description: Access to a self-regulation based mobile application.
Study NCT05812794 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation (tDCS)
Description: Participants will come for 5 sequential days of 2 hour long occupational therapy sessions augmented by tDCS for the first 20 minutes of the session. At arrival, the stimulation safety sheet will be completed by the occupational therapist.The saline soaked electrodes will be placed on the study subjects head and connected to the Soterix 1x1 Limited Total Energy (LTE) enabled tDCS device. Current output through the device will be sham stimulation on day 1 , followed by steady increases to a maximum of 1milliampere (mA) in patients aged 5-12 years old, and 1.5 mA in patients aged 13-19 years old, per the study design flow sheet at the end of this protocol. Blood pressure, pulse rate, and peg-board scores will be recorded as indicated on the stimulation safety sheet during each session.A repeat assessment will be done by the occupational therapist one week post therapy completion.There will be a repeat assessment visit 3 months post intervention.
Study NCT06110117 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sterimar Stop & Protect Irritation & Dryness
Description: One or two nasal sprays will be administered to each nostril for a minimum of 2 times per day up to a maximum of 6 times per day for seven days.
Study NCT05804396 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Relivion®
Description: Active stimulation device
Study NCT05493371 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 10 MG
Description: 10 mg once daily empagliflozin oral tablets for 12 weeks
Study NCT06693960 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oregano
Description: Oil of oregano administered as a softgel (180 mg).
Study NCT06693960 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug cocktail
Description: Oral drug cocktail consisting of caffeine (100 mg), dextromethorphan (30 mg), losartan (25 mg), midazolam syrup (2 mg), and omeprazole (20 mg).
Study NCT06695312 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: selected exercise program
Description: therapeutic ultrasound, Static neck exercise
Study NCT06695312 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: High Tone Power Therapy
Description: High Tone Power Therapy delivered in cervical region 3 times per week for four weeks