AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06700421 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Adebrelimab + Apatinib
Description: Adebrelimab combined with apatinib
Study NCT03697343 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Radiosurgery
Description: Radiosurgery with 1 x 18 Gy (2-3 cm) or 1 x 15 Gy (3-4 cm)
Study NCT06701604 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Single Strain Probiotic + Milk Protein
Description: • Both conditions matched flavor, color, and serving size
Study NCT06701604 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo + Milk Protein
Description: • Both conditions matched flavor, color, and serving size
Study NCT06701487 — intervention group
Intervention type: BIOLOGICAL
Intervention: fMRI imaging (BOLD)
Description: Will be used to investigate neural correlates of Pavlovian-to-instrumental transfer (PIT) effects by measuring the blood oxygenation level dependent (BOLD) response of neural activation in the mesolimbic system.
Study NCT06701487 — intervention group
Intervention type: BIOLOGICAL
Intervention: sMRI (structure)
Description: Will be used to investigate neural correlates of PIT effects by identifying abnormalities in cortical gray and white matter volume.
Study NCT06701487 — intervention group
Intervention type: BEHAVIORAL
Intervention: Pavlovian-to-instrumental transfer (PIT) paradigm
Description: The paradigm consists of four parts:~In the first part, an instrumental learning task is completed in which subjects must learn which stimuli require a response and which do not. In the second part, a classical (Pavlovian) conditioning task is then completed in which subjects learn by passive viewing which stimuli are associated with certain amounts of money. The third part measures to which instrumental responses (learned in Part 1) are modulated by the presentation of the classically conditioned stimuli (learned in Part 2). At the same time drug-associated stimuli are presented in the background measuring to which extent they conflict with the learned instrumental behavior. In the last part, query trials are implemented in which the participants have to choose between two pictures to assess the relative cue value.
Study NCT06701487 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Basic psychological assessment (interview)
Description: * Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)~* Quantity Frequency: Alcohol, Cannabis, (Meth-) Amphetamine, Cocaine)~* SCID: AUD and SUD (Cannabis, Methamphetamine, Amphetamine, Cocaine) criteria and last year \& depressive symptoms \& symptoms for Mania and psychotic disorder (acute and lifetime) MiniDIPS psychotic disorders
Study NCT06701487 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Basic psychological assessment (questionnaires)
Description: * Sociodemographics~* Edinburgh Handedness Inventory (EHI)~* Fagerström Test for Nicotine depend (FTND)~* Barratt Impulsiveness Scale - Kurzversion (BIS-15)~* Allgemeine Depressionsskala (ADS)~* State-Trait-Anxiety Inventory (STAI-T and STAI-S)~* Adult ADHD Self-Report Scale (ASRS)~* Alcohol Use Disorders Identification Test (AUDIT)~* CAS -A (Alkohol)~* Cannabis Use Disorders Identification Test (CUDIT)~* Fragebogen zu Gedanken und Gefühle 14 Items (FGG-14)~* Fragebogen zur Sozialen Unterstützung (F-SozU-K14)~* Trierer Inventar zum chronischen Stress (TICS)~* Oslo 3-Items-Social-Support Scale (Oslo-3)~* Social Readjustment Rating Scale (SRRS)~* International Trauma Questionnaire (ITQ)~* Positive and Negative Affect Schedule (PANAS)
Study NCT06701487 — intervention group
Intervention type: BEHAVIORAL
Intervention: Neuropsychological tests
Description: * Digit-Symbol-Test (DST)~* Digit Span Task~* Value-based decision-making task (VBDM)
Study NCT06703866 — intervention group
Intervention type: OTHER
Intervention: Non Small Cell Lung Cancer (NSCLC)
Description: Application of value based medicine predictive model
Study NCT06301477 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistant Starch
Description: 7.5g/m2 or 5.0g/m2 (body surface area) resistant starch oral consumption
Study NCT06301477 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo oral consumption of food-grade cornstarch
Study NCT06425146 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Cytobrush sample
Description: Healthy oral mucosa will be collected using a cytobrush, which is a minimally invasive method for patients
Study NCT06425146 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Blood sampling
Description: Blood sampling (6 mL), taken from a routine biological exam
Study NCT03904498 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tolcapone
Description: Tolcapone 100 mg tablets
Study NCT03904498 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo tablets
Study NCT04136626 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Perspectives OCD
Description: The app-delivered cognitive behavioral therapy (CBT) in this project includes modules such as cognitive skills (e.g., cognitive restructuring, core belief work) and behavioral skills (e.g., exposure and response prevention).
Study NCT04136626 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: The Health and Well-Being Program
Description: The website includes 12 modules related to general health and well-being (e.g., sleep and nutrition). Each module contains educational information and questions about an indvidual's experience with the given topic.
Study NCT04648774 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Serratus anterior plane (SAP) block
Description: With the patient in supine position, an ultrasound transducer will be used to find the 4th rib in the mid-axillary line. A 17g touhy needle will be introduced in-plane in an inferior to superior direction until its tip rests between the serratus anterior muscle and the 4th rib or the 3rd external intercostal muscle. A bolus of study drug 10ml (either ropivacaine 0.2% or normal saline) will be delivered though the needle. A 18g multiholed catheter will be inserted and secured to the patients' skin with adhesive dressings. A further 10ml of study drug will be administered through the catheter. The same procedure will be followed on the contralateral side. The study drug will be administered by programmed intermittent bolus (PIB) 10ml every 2 hours to each side in a staggered, alternating fashion. The PIB study drug will to be continued for 72 hours post-insertion.
Study NCT04648774 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline placebo
Description: Patients in both groups will receive the standard of care analgesic medications in the cardiovascular intensive care unit and the ward.
Study NCT05346237 — intervention group
Intervention type: BEHAVIORAL
Intervention: Quality of life questionnaire
Description: Filling out questionnaires, measuring maximum phonation and diadochokinesis
Study NCT05789303 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin
Description: Cycles 1, 3, 5, 7, etc. (odd numbered cycles): 1.9 mg/kg IV on Day 1 (28-day cycles)
Study NCT05789303 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib
Description: Cycle 1: 20 mg/m2 on Day 1, then 56 mg/m2 on Days 8/15~Cycles 2-8: 56 mg/m2 on Days 1/8/15~Cycles 9+: 56 mg/m2 on Days 1/15
Study NCT05789303 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: 3 mg Day 1-21 of 28-day Cycle
Study NCT05789303 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Cycles 1-4: 40 mg Days 1/8/15/22~Cycles 5+: 20 mg Days 1/8/15/22
Study NCT05265624 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early disclosure of genetic testing results
Description: Early disclosure group receives results of genetic testing at Month 1
Study NCT05265624 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Late disclosure of genetic testing results
Description: Late disclosure group receives results of genetic testing at Month 12
Study NCT05340023 — intervention group
Intervention type: BIOLOGICAL
Intervention: blood sample
Description: to realize proteomic analysis.
Study NCT06138756 — intervention group
Intervention type: DEVICE
Intervention: Nerivio
Description: Neriio is a remote electrical neuromodulation (REN) device for the treatment of migraine
Study NCT05155046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-DCFPyL
Description: 18F-DCFPyL imaging will be performed at baseline, 8 weeks after ADT initiation, 6 months post SBRT and at recurrence. The target administered activity will be 6.5 mCi with a lower limit of 6 mCi.
Study NCT04950803 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Microbiome immunity formula
Description: Microbiome immunity formula contains probiotics blend (3Bifidobacteria, 20 billion CFU daily)
Study NCT04950803 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Active placebo
Description: Active placebo contains active vitamin
Study NCT04824144 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine Hydrochloride
Description: Dexmedetomidine will be administered by subcutaneous continuous infusion using a Continuous Ambulatory Delivery Device (CADD pump).
Study NCT06279481 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nonpharmacological method
Description: Virtual reality
Study NCT06452615 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extracorporeal shockwave
Description: The patients will receive 3000 to 6000 pulses every session by a radius of 15 mm probe (R15) at a frequency of 10 Hz, with energy gradually increasing from 1.4 to 1.5 bar
Study NCT04748380 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CRC decision aid pamphlet
Description: A newly developed 8-10 page decision aid pamphlet that discusses:1. Information on CRC; 2. Information about risk and benefits including the 10-year lag-time to benefitting from CRC screening; 3. Information to help patients evaluate CRC screening options (colonoscopy or stool testing); 4. Possible outcomes relevant to LE and health status. In addition, there will be a values clarification exercise
Study NCT04748380 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Home Safety Pamphlet
Description: The home safety information pamphlet is a 2-page fact sheet on home safety tips for older adults, and was designed by the AGS Health in Aging Foundation. It includes information in seven areas to help older adults stay safe in their homes. Areas include but are not limited to fall prevention and safety proofing homes. It has been used successfully in prior studies of DAs as a control intervention
Study NCT03697343 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Fractionated stereotactic radiotherapy
Description: Fractionated stereotactic radiotherapy with 12 x 4 Gy and 2 mm
Study NCT05988411 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Renal Denervation
Description: Renal denervation using the Paradise renal denervation system - a dedicated Renal Denervation (RDN) catheter that delivers a circumferential ring of ablative ultrasound energy
Study NCT04724811 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open reduction and internal fixation (ORIF)
Description: Approaches used:~* Intrapelvic approach +/- iliac window~* Kocher-Langenbeck approach
Study NCT04724811 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Open reduction and internal fixation (ORIF)
Description: Approaches used:~* Intrapelvic approach +/- iliac window~* Kocher-Langenbeck approach
Study NCT04909697 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sivelestat sodium
Description: 4.8mg/kg sivelestat sodium was given in 50ml normal saline, and was continuously pumped in the dark for 24h, equivalent to 0.2mg/kg/h.Applied for 5 consecutive days
Study NCT04909697 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Saline
Description: 50ml normal saline was continuously pumped in the dark for 24h. Applied for 5 consecutive days
Study NCT06573086 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: 12-week resistance training
Study NCT06572319 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab Vedotin(RC48) Plus Tratuzumab
Description: Disitamab Vedotin: 2.5mg/kg，ivgtt，D1, every 2 weeks for a treatment cycle. Tratuzumab: RP2D，ivgtt，D1, every 2 weeks for a treatment cycle.
Study NCT05988411 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Catheter Ablation
Description: Catheter ablation - one of the most common procedures performed by Cardiac Electrophysiologists for atrial fibrillation.
Study NCT05988411 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Catheter Ablation
Description: Catheter ablation - one of the most common procedures performed by Cardiac Electrophysiologists for atrial fibrillation.
Study NCT06574087 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: hrHPV test and cytology
Description: Perfomance of hrHPV test and cytology
Study NCT06574087 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: hrHPV test and cytology
Description: Perfomance of hrHPV test and cytology
Study NCT06259344 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Fractioned Pain Science Education (FPSE)
Description: Pain Science Education (PSE) will be administered in workshop sessions with interactive presentations, using different resources as metaphors and videos. It will be held in 2 sessions of 45 minutes each, covering 6 topics of Explain Pain and Explain Pain Supercharged books.
Study NCT06259344 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Full Dosage Mode Pain Science Education (FDPSE)
Description: Pain Science Education (PSE) will be administered in workshop sessions with interactive presentations, using different resources as metaphors and videos. It will be held in 6 sessions of 15 minutes each, covering 6 topics of Explain Pain and Explain Pain Supercharged books.
Study NCT06259344 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Therapy
Description: Intraoral temporalis release, Intraoral medial and lateral pterygoid (origin) technique and Intraoral sphenopalatine ganglion technique.
Study NCT06259344 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy
Description: Intraoral temporalis release, Intraoral medial and lateral pterygoid (origin) technique and Intraoral sphenopalatine ganglion technique.
Study NCT06259344 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Orofacial and Neck Exercises (ONE)
Description: Orofacial Exercises: Mandibular body-condylar cross-pressure chewing technique; Post-isometric relaxation stretches-laterotrusion and opening (10 times/session; 10 seconds).~Neck Motor Control Exercises: Bracing exercises (6 hierarchical levels - HL). Extreme range of motion exercises (stable spine). Cervical isometric exercises (5 HL) directly forward, obliquely, toward right and left, and directly backward (stable spine - elastic resistive bands). Functional training with elastic resistance and exercise balls on unstable surfaces (8 HJ). The progress in each exercise domain will happen when sustaining the contraction for 10 seconds, 10 times.
Study NCT06259344 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Orofacial and Neck Exercises (ONE)
Description: Orofacial Exercises: Mandibular body-condylar cross-pressure chewing technique; Post-isometric relaxation stretches-laterotrusion and opening (10 times/session; 10 seconds).~Neck Motor Control Exercises: Bracing exercises (6 hierarchical levels - HL). Extreme range of motion exercises (stable spine). Cervical isometric exercises (5 HL) directly forward, obliquely, toward right and left, and directly backward (stable spine - elastic resistive bands). Functional training with elastic resistance and exercise balls on unstable surfaces (8 HJ). The progress in each exercise domain will happen when sustaining the contraction for 10 seconds, 10 times.
Study NCT05600868 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A comprehensive third-generation intervention EMDR + dual attention
Description: This is a individual intervention with a total of 10 sessions. In the processing the traumatic event phase will be realized with double attention.
Study NCT05600868 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A comprehensive third-generation intervention EMDR + fixed point
Description: This is a individual intervention with a total of 10 sessions. In the processing the traumatic event phase will be realized with fixed point.
Study NCT05600868 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A comprehensive third-generation intervention EMDR + exposition
Description: This is a individual intervention with a total of 10 sessions. In the processing the traumatic event phase will be realized with exposition.
Study NCT06236152 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ferrous sulfate
Description: Ferrous Sulphate was given once daily for 4 to 6 weeks to the patients instead of deltacortil.
Study NCT06236152 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Deltacortril
Description: Deltacortil 10mg was given orally once daily for 4 to 6 weeks
Study NCT05755919 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Epilepsy surgery
Description: Epilepsy surgery will be performed as a part of the clinical management of patients with drug-resistant epilepsy.
Study NCT05214651 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: novel double row
Description: The large - massive rotator cuff tears in in this group will be treated using a novel double row repairing techniques.
Study NCT05214651 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: suture bridge double row
Description: The large - massive rotator cuff tears in in this group will be treated using a suture bridge double row repairing techniques.
Study NCT05092802 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX208
Description: 450mg bid po
Study NCT06104592 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Comprehensive Ablative Bridging Irradiation (CABI)
Description: Participants will receive radiation therapy to all pretreatment lesions that are able to be feasibly and safely treated.
Study NCT06104592 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Chimeric Antigen Receptor T-Cell Therapy
Description: Yascarta is an autologous anti-CD19 CAR T cell therapy manufactured from the patient's own T cells, which have been extracted and then reprogrammed with CAR molecules to help the T cells recognize cancer cells. The reengineered T cells are infused back into the patient to attack the cancer.
Study NCT06267118 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hypertonic Saline Solution, 1 Ml
Description: Dilute 0.3 ml hypertonic saline with 3 ml normal saline for nebulization
Study NCT06267118 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adrenaline
Description: dilute 0.3 ml adrenaline with 3 ml normal saline for nebulization
Study NCT04460521 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-Acetyl cysteine
Description: In addition to splinting, both groups will receive an oral tablet to take daily for 8 weeks. Participants assigned to the experimental group will receive oral NAC (500 mg PO daily for eight weeks; based on recommended daily dose for use as an antioxidant and dosing in previous human clinical trials and animal studies), and those assigned to the control group will be given a similar looking placebo with identical instructions. Tablets will be provided in a blister pack to assist with compliance.
Study NCT04460521 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Wrist Splint
Description: Participants in both arms will be given a standard prescription for a prefabricated night splint which keeps the wrist in a neutral position and instructed on proper use and the importance of consistent use. To limit splint variability, we will ensure that splint prescriptions are written such that a MedSpec Wrist Lacer II splint is obtained from the patient's pharmacy. This is the most commonly available brand locally and meets the criteria for wrist, metacarpophalangeal, and interphalangeal joint positioning. They will be advised to wear the splint consistently during sleeping hours on their affected wrist for eight weeks, as is the standard of practice.
Study NCT04460521 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Wrist Splint
Description: Participants in both arms will be given a standard prescription for a prefabricated night splint which keeps the wrist in a neutral position and instructed on proper use and the importance of consistent use. To limit splint variability, we will ensure that splint prescriptions are written such that a MedSpec Wrist Lacer II splint is obtained from the patient's pharmacy. This is the most commonly available brand locally and meets the criteria for wrist, metacarpophalangeal, and interphalangeal joint positioning. They will be advised to wear the splint consistently during sleeping hours on their affected wrist for eight weeks, as is the standard of practice.
Study NCT06115759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: T-REX Twente precautions
Description: The intervention group receives the new T-REX Twente precautions, allowing for more independent activities through the use of the tube model (keeping elbows close to the sides).
Study NCT06115759 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual (restrictive) sternal precautions
Description: The control group is not allowed to lift, push, or pull for the first 6 weeks. There is little to no evidence for the current strict precautions currently implemented in the department.
Study NCT05774067 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Saline
Description: patient received normal saline 4ml/kg/hr with deflation of tourniquet