AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05226169 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ferinject
Description: * Patients will receive an IV FCM (1,000 mg iron) infusion on the first day (visit 1) of chemotherapy. FCM (FerinjectTM; Vifor Pharma, Glattbrugg, Switzerland) will be diluted in 250 ml of sterile 0.9% normal saline by an aseptic technique and infused over 15 min under the supervision of a clinician.~* Patients with a Hb level ≤ 10 g/dL and ID (serum ferritin \< 100 ng/mL or TSAT \< 50% and serum ferritin 100-500 ng/mL) will receive an additional dose of 500 mg of IV FCM at 6, 12, 24, 36, and 48 weeks. FCM will be diluted in 100 ml of sterile 0.9% normal saline by an aseptic technique and infused over 6 min under the supervision of a clinician.
Study NCT05226169 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative management
Description: * Patients with absolute (must be administered) or functional (according to the physician's choice) IDA in the control arm will be received oral iron, administered as Feroba-You 256mg once or twice a day. Advice will be given regarding ingestion without food and with liquid high in ascorbic acid to maximize enteric absorption.~* If patients in the control arm still meet the absolute or functional IDA at the end of study (at 48 weeks), they can receive IV FCM (1,000 mg) according to the physician's decision.
Study NCT04980001 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Families OverComing Under Stress Trauma Informed Care in Childhood Obesity among Minorities (FOCUS TIC-COM)
Description: FOCUS TIC-COM is a program that helps doctors coach families to recognize how emotions or feelings about various life stressors may affect a child's dietary choices and physical activity. FOCUS TIC-COM is for families of children who have been identified by their doctor as overweight or obese. The goal of the program is to help children and their families understand how their mental health may impact their physical health and develop strategies to address their mental health needs.
Study NCT04840797 — intervention group
Intervention type: DEVICE
Intervention: HeartStart HS1
Description: Automated External Defibrillator
Study NCT06143722 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: simultaneous with radiotherapy
Description: Chemotherapy combined with immunotherapy simultaneous with radiotherapy
Study NCT06143722 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: synchronous with radiotherapy
Description: Chemotherapy combined with immunotherapy synchronous with radiotherapy
Study NCT06219473 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fascia lata membrane
Description: novel allogenic derived acellular matrix produced from human fascia lata allograft
Study NCT06219473 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Platlet Rich fibrin membrane
Description: Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRF where autologous platelets and leukocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue
Study NCT06219473 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: subepithelial connective tissue graft
Description: The connective tissue is generally taken from the hard palate, although it may be taken from other sites as well, such as the maxillary tuberosity area.
Study NCT05791032 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AtaCor EV-ICD Lead
Description: Subjects will receive the AtaCor EV-ICD Lead being evaluated in the study.
Study NCT03348670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone - Usual
Description: * Oral~* Abiraterone Combined Chemotherapy (high dose)
Study NCT03348670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abiraterone - Study
Description: * Oral~* Abiraterone Combined Chemotherapy (low dose)
Study NCT05702567 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RF + PFMT
Description: During each session the patient is lying face up, with knees bent and feet resting on the stretcher.~Then, the vaginal probe is introduced into the cavity using a lubricant suitable for intracavitary use and radiofrequency. The device is started at 15% intensity and adapting to a 10-point Likert scale, at point 3 or 4 of intensity.~At the same time that the radiofrequency is applied, pelvic floor contractions are performed guided by the physiotherapist, and these contractions are three:~* 10 fast contractions of one second each, with 10 seconds of rest.~* 5 seconds of sustained contraction and 10 seconds of rest.~* 10 seconds of contraction maintained with 10 seconds of rest.~The contraction maintenance time will be adapted to what each woman can keep the pelvic floor contracted, with a view to the goal being to complete these exercises cyclically during the entire session.
Study NCT05702567 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: PFMT + Placebo RF
Description: The intervention is exactly the same as the group RF + PFMT, unlike the non-functioning of the RF in the patients belonging to this group.~The patient is lying face up, with knees bent and feet resting on the stretcher. Then, the vaginal probe is introduced into the cavity using a lubricant suitable for intracavitary use and radiofrequency, the device is started at 15% intensity, but in this case, the program does not work or apply radiofrequency to the patients.~At the same time, that the radiofrequency's probe is applied, pelvic floor contractions are performed guided by the physiotherapist, and these contractions are the three named in the Radiofrequency + PFMT.~The contraction maintenance time will be adapted to what each woman can keep the pelvic floor contracted, with a view to the goal being to complete these exercises cyclically during the entire session.
Study NCT05564247 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wheelchair Skills Training Program (WSTP)
Description: Participants will complete customized MWC skills training based on the evidence-based wheelchair skills program. Lessons plans will be created by the clinicians, children and parents participants based on goals, age, skills and interests, and used to customize the training.
Study NCT06677970 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BP lowering drugs (nicardipine, labetalol, urapidil)
Description: After successful reperfusion, appropriate antihypertension medication is administered to control systolic blood pressure \<180 mmHg.
Study NCT06677970 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil)
Description: After successful reperfusion, appropriate BP raising (20% increase in SBP, maximum of 180 from baseline SBP) are administered.
Study NCT05539222 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Food vouchers and education
Description: Intervention and control group individuals received 120 euros/month during 3 months in food vouchers to be spent in supermarkets (60 euros/month if under 12y) plus a 10-week nutrition education for the intervention group. Family food purchases were assessed using electronically recorded supermarket-obtained transactions.
Study NCT04849520 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High flow nasal cannula
Description: Oxygen supplement via high flow nasal cannula at a rate of 2 liters/kg/min
Study NCT04849520 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Buccal oxygenation
Description: Oxygen supplement intra-orally via oral Ring-Adair-Elwyn endotracheal tube connected to oxygen at a rate of 0.5 liters/kg/min
Study NCT06282705 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 0cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 0 cm (floor). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.
Study NCT06282705 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 40cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 40 cm (plyo box). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.
Study NCT06282705 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diagonal Drop Jumps 60cm
Description: Participants will complete 4 unsupervised home drop jump sessions per week ( minimum 24 hours between each session) for the duration of the study (e.g., Mon, Wed, Fri, Sun) from a height of 60 cm (plyo box). They will perform 20 diagonal drop jumps on each side (20 x dropping left and 20 x dropping right) with 30 seconds between each jump. The routine will be demonstrated in full on the first laboratory session. The intervention will last 16 weeks.
Study NCT04922112 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Obstructive sleep apnea testing
Description: * Functional Outcomes of Sleep Questionnaire (FOSQ-10)~* European Organization for Research and Treatment of Cancer Head and Neck Survey (EORTC HN 35)~* Epworth Sleepiness Scale (ESS)~* Adult Comorbidity Evaluation (ACE 27)~* University of Washington Quality of Life Questionnaire (UW-QOL)~* Chronic Pain Assessment Questionnaire
Study NCT05065229 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oxygen saturation probe Mindray 520 N and Mindray 521 N
Description: Two oxygen saturation probes will be used in this study:~Mindray 520 N is a disposable oxygen saturation sensor for neonates and adults. It is a disposable, single-use sensor that is wrapped around the infant's arm or foot. Its ends stick together giving a firm, close contact with the skin.~Mindray 521 N is another disposable oxygen saturation sensor for neonates and adults that is used on the neonatal unit in routine practice. As Mindray 520 N and 521 N are CE marked and used within their intended purposes we do not require a letter of no objection from the MHRA for that usage. The Mindray probes will be used without modification and there are no safety issues to the patient. Therefore, a letter of no objection from the MHRA is not required and this is not a medical device study under the Medical Devices Directive.
Study NCT06125483 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Umbilical Cord Blood Transplantation
Description: Compared with peripheral blood stem cell transplantation (PBST), UCBT has a higher transplantation rate, as cord blood stem cells are more primitive. Since the first successful umbilical cord blood transplantation (UCBT) in a child with severe Fanconi anemia reported by Gluckman et al. in France in 1988, cord blood has been widely used as a graft source of hematopoietic stem cells for the treatment of hematological diseases. The first sibling UCBT for leukemia was performed successfully by Professor Yongping Song in China, who played a pioneering role in the development of UCBT for leukemia in China. On the basis of previous research, TBI/Flu/Bu/Mel combined with UCBT is safe and feasible for the treatment of patients with malignant hematological diseases who experienced post-transplant relapse, which has enormous potential to improve patient outcomes.
Study NCT05619783 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AMX0035
Description: Combination of 3 g phenylbutyrate and 1 g taurursodiol
Study NCT05815056 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sedakit (R) using hypnosis induced by the virtual reality device
Description: we use the virtual reality device and no medication during the surgery
Study NCT05815056 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: drug intervention
Description: using sufentanyl 5mg intravenously during the surgery
Study NCT06370221 — intervention group
Intervention type: BEHAVIORAL
Intervention: The effect of psoriatic Arthritis
Description: to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.
Study NCT06766409 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A community group-based demonstration counseling method
Description: At the community level, a perinatal woman in the intervention arm will get individual family planning counseling along with group-based counseling that includes a planned demonstration of all possible techniques.
Study NCT06766409 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: An individual family planning counseling
Description: The control group's pregnant and postpartum women will simply get standard individual FP counseling in accordance with Ethiopian national recommendations.
Study NCT06750224 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alexander technique
Description: 24 sessions for 8 weeks, per week 3 sessions will be given
Study NCT06750224 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Feldenkrais method
Description: The method is divided into eight lessons according to 'Awareness Through Movement'. Each lesson will be given three times for one week.
Study NCT06766149 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CogniFit Computerized Cognitive Training
Description: In the CogniFit Computerized Cognitive Training, children will complete a range of tasks covering a range of game-like exercises targeting various cognitive skills, including working memory, attention, and inhibitory control, with automatic level advancement after each exercise.
Study NCT06766149 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cogmed Computerized Cognitive Training
Description: In the Cogmed Computerized Cognitive Training, children will complete a range of tasks covering a range of game-like exercises targeting various cognitive skills, including working memory and attentional control, with automatic level advancement after each exercise.
Study NCT06775093 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLP-1 receptor agonist
Description: 3 months
Study NCT06775093 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: 3 months
Study NCT06775093 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: 3 months
Study NCT06775093 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: healthy lifestyle education
Description: 3 months
Study NCT06775093 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: healthy lifestyle education
Description: 3 months
Study NCT06775002 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Serum Raman spectroscopy intelligent diagnostic system
Description: 1. Screening interested participants should sign the appropriate informed consent (ICF) prior to completion any study procedures. 2. The investigator will review symptoms, risk factors, and other non-invasive inclusion and exclusion criteria. 3. The following is the general sequence of events during the 3 months evaluation period. 4. Completion of baseline procedures Participants were assessed for 3 months and completed all safety monitoring.
Study NCT06774222 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquinitinib: Take 4 mg QD for 2 weeks and stop for 1 week, every 3 weeks for a cycle; Standard chemotherapy: The selection of drugs is recommended by the 2024CSCO Guidelines for the Diagnosis and Treatment of Gastric Cancer, including SOX, XLOX or S-1, and the treatment cycle is one every 3 weeks
Study NCT06775106 — intervention group
Intervention type: OTHER
Intervention: There is no intervention in this observational study
Description: No direct intervention will be done to patients eligible for the study. There will be a shunt placed to divert 5-15% of exhaled breath into a collection tube. This will not affect the patient's existing standard medical care.
Study NCT06771375 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing
Description: EMDR is a psychotherapeutic approach originally designed for individuals suffering from trauma and post-traumatic stress disorder (PTSD). It facilitates the processing of memories through a structured eight-phase treatment, involving the patient's focused attention on traumatic images, thoughts, and sensations while simultaneously engaging in bilateral stimulation, typically through guided eye movements. This process aims to reduce the emotional distress associated with aversive memories, promoting adaptive coping mechanisms and psychological healing. Recently, the indications for the method have been extended so that EMDR is also used for chronic pain and depressive disorders.
Study NCT06772428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nano-crystalline Megestrol Acetate Oral Suspension
Description: Nano-crystalline Megestrol Acetate Oral Suspension, with a specification of 125 mg/mL, the study group takes 5 mL orally per day (625 mg/day), and continues medication; after completing the treatment cycle, patients who are assessed by the researchers as suitable for continued treatment may continue to receive therapy.
Study NCT06772428 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: standard treatment
Description: radiotherapy ± chemotherapy
Study NCT06772428 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: standard treatment
Description: radiotherapy ± chemotherapy
Study NCT06771362 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ART with Bulk-Fill composite
Description: Restoration using Bulk-fill flowable self-cured composite
Study NCT06771362 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: ART with Glass Ionomer
Description: Restoration Using High-Viscosity Glass Ionomer Cement
Study NCT06770062 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac MRI
Description: Each subject will receive two cardiac MRI scans (with and without contrast), one preoperative and another 6-12 months after. The duration of each MRI is approximately 45-60 minutes
Study NCT06771882 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: BMOS technique
Description: The researcher obtained 5cc soaked in a 2cm×2 cm piece of sterilized gauze for every intervention administration.~* The preterm neonates were positioned in the supine position and the head turned to one side~* The gauze was placed near the head, 2cm away from the nose for 2 minutes before feeding to stimulate an olfactory sense of preterm neonates 3 times per day (11 am, 2 pm, and 5 pm).
Study NCT06773650 — intervention group
Intervention type: OTHER
Intervention: Completion of online survey
Description: The online survey aims to reach a representative sample of the Italian population to identify their knowledge regarding LI
Study NCT06771349 — intervention group
Intervention type: PROCEDURE
Intervention: sigmoidopexy
Description: Both Sigmoidectomy and sigmoidopexy can be used for the treatment of sigmoid volvulus. The former is the treatment of sigmoid volvulus by removing a portion of the sigmoid colon, and depending on the patient's condition, a bowel reconstruction or anastomosis may be performed to reattach the healthy bowel segment. The procedure may result in long-term bowel changes and may even require an stomy. sigmoidopexy is a procedure that immobilizes the sigmoid colon to the abdominal wall or pelvic structure, preventing it from twisting again.~The goal of sigmoidectomy is primarily to remove damaged or necrotic portions of the sigmoid colon and to treat complications resulting from sigmoid volvulus, especially when the volvulus results in intestinal necrosis, ischemia, or other serious complications. The goal of sigmoidopexy is to prevent the sigmoid from re-twisting by immobilizing the sigmoid, and it is suitable for those cases of sigmoid torsion without severe ischemia or necrosis.
Study NCT06771661 — intervention group
Intervention type: OTHER
Intervention: Workshops
Description: The investigators will conduct workshops with parents to get closer to the main topic.
Study NCT06771661 — intervention group
Intervention type: OTHER
Intervention: Focus group interviews
Description: The investigators will conduct focus group interviews with parents on their needs before and during child loss.
Study NCT06771661 — intervention group
Intervention type: OTHER
Intervention: Narrative interviews
Description: The investigators will conduct narrative interviews with parents to gain an in-depth understanding of their lived experience before and during the intrauterine or perinatal child loss.
Study NCT06771661 — intervention group
Intervention type: OTHER
Intervention: Delphi approach
Description: The investigators will carry out a Delphi approach with parents to translate and confirm or revise the findings into treatment recommendations for healthcare professionals.
Study NCT04982848 — intervention group
Intervention type: DRUG
Intervention: Talzenna
Description: Talzenna treatment under Korea regulatory approval indication/dosage
Study NCT05488197 — intervention group
Intervention type: OTHER
Intervention: uterine artery doppler at 18-23 weeks of pregnancy
Description: uterine artery doppler at 18-23 weeks of pregnancy
Study NCT02393482 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Estroprogestinic therapy (Etinil-estradiol/levonorgestre)
Description: Etinil-estradiol/levonorgestrel (100 mcg/20 mcg)/die
Study NCT02393482 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gonadotropin-releasing hormone agonist (Leuprorelin acetate)
Description: Leuprorelin acetate (3,75 mg/2 ml)/month
Study NCT02393482 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Add back therapy 1 (tibolone)
Description: tibolone 5 mg/die
Study NCT02393482 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Add back therapy 2 (calcium carbonate/colecalciferol)
Description: calcium carbonate/colecalciferol (500mg/400UI)/die