AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06170723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Specified dose on specified days
Study NCT06170723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine
Description: Specified dose on specified days
Study NCT04742140 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium sulfate
Description: each patient injected 0.5ml in each TrPs of magnesium sulphate according to the treatment group by the same operator
Study NCT04742140 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Saline
Description: each patient injected 0.5ml in each TrPs of saline according to the treatment group by the same operator
Study NCT06201702 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: pomegranate extract
Description: Drink 2 mL of pomegranate extract three times a day for 10 days during the 3 menstrual cycles (from 7 days before to 3 days after the estimated onset of menstruation).
Study NCT05174260 — intervention group
Intervention type: DEVICE
Intervention: perfusion index, pleth variable index
Description: a clip will be attached to the patient's finger and the perfusion index and pvi will be measured
Study NCT06463249 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CORE Helpline
Description: All participants will receive the Core Helpline program (CORE) for 2 months, which includes written weight loss material, use of a smartphone app, weekly text messages and email reminders and 1 optional participant-initiated coaching call per month.
Study NCT06463249 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CORE Helpline
Description: All participants will receive the Core Helpline program (CORE) for 2 months, which includes written weight loss material, use of a smartphone app, weekly text messages and email reminders and 1 optional participant-initiated coaching call per month.
Study NCT06267716 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PENG block
Description: preoperative ultrasound-guided pericapsular nerve group block
Study NCT06267716 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IPB
Description: preoperative ultrasound-guided iliopsoas plane block
Study NCT05017168 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-P63
Description: CT-P63 will be administered
Study NCT05017168 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo-matching CT-P63
Study NCT04966715 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Epigastric lymph node biopsy
Description: epigastric lymph node biopsy and analysis to evaluate rate dissemination of colorectal carcinomatosis by this way
Study NCT05379192 — intervention group
Intervention type: OTHER
Intervention: Group 1, Group 2, Group 3, Group 4
Description: The total amount of antiemetic,the time of first antiemetic use and VAS scores at 1, 2, 3, 6, 9, 12, 15, 18, 21 and 24th hours postoperatively will also be recorded according to circadian rhythm
Study NCT06290531 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Flavored Benzocaine topical anesthetic gel 20%
Description: Topical anesthetic gel
Study NCT05057468 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine
Description: 2.5-5 mg orally for 3 months
Study NCT05057468 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: 375 mg/ m2 weekly dose for a maximum of 4 weeks
Study NCT04847739 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Seton Placement
Description: This treatment consists of inserting a seton (a soft flexible tube or nonabsorbable string) into the subject's perianal fistula. The seton will be removed by a study doctor at study visits as applicable.
Study NCT04847739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Seton Placement
Description: This treatment consists of inserting a seton (a soft flexible tube or nonabsorbable string) into the subject's perianal fistula. The seton will be removed by a study doctor at study visits as applicable.
Study NCT04847739 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AVB-114
Description: AVB-114 consists of stem cells taken from a subject's fat tissue seeded into a bioabsorbable plug. AVB-114 will be inserted into the subject's fistula by a study doctor on Day 0.
Study NCT05615155 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Platelets Rich Fibrin (i-PRF / C-PRF)
Description: one site of the mouth will be injected with i-PRF and the other site will be injected with C-PRF
Study NCT04705428 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FLUORINE VARNISH
Description: Participants in all groups will receive written oral hygiene and oral prophylaxis instructions. All groups will receive the application of fluorine varnish every 3 months.~The application of fluoride in the three groups will be done as follows:~-Drying of the teeth, placement of the fluorine varnish on the teeth by quadrants. The varnish will be left to dry for a few seconds according to the manufacturer's instructions. Children in all groups will be asked to avoid brushing and flossing for one day after applying fluoride. They will be instructed to avoid hard food and hot drinks for 4 hours. Children and parents will be instructed on how to care for their teeth at home: brush teeth with conventional toothpaste containing 1000 ppm sodium fluoride, for 3 minutes without rinsing.~In the following reviews (3 and 6 months) the effectiveness of the treatments will be evaluated by visual examination, tactile examination, fluorescence and photography.
Study NCT06417398 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: T cell injection targeting CD19 chimeric antigen receptor
Description: Intravenous administration, 1 bag each time (depending on individual differences), dose: 1×108-1×109 CD19-CAR-gdT (UTAA09 injection), the investigator can decide whether to reduce or increase the dose and whether multiple infusions are required according to the condition of the subject.
Study NCT06300320 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ05105 tablets
Description: Rovadicitinib (TQ05105) is a novel, oral dual JAK 1/2 and Rho-associated kinases (ROCK) 1/2 inhibitor targeting inflammatory and fibrotic components of cGVHD.
Study NCT05408585 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regional Anesthesia Techniques
Description: Fascial Plane Blocks
Study NCT06346509 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PORT-77
Description: Healthy adult participants will receive a single oral dose of PORT 77.
Study NCT06346509 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Healthy adult participants will receive matching placebo on Day 1.
Study NCT05562206 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CGMIS (Continuous Glucose Monitoring Infusion Set)
Description: An integrated combination CGM/insulin infusion system
Study NCT05119374 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SenseGuard Investigational Device
Description: SG is a wireless, wearable medical device, which includes nano-based sensors. It can seamlessly measure patient's tidal breathing during daily activities. SG extracts series of critical respiratory parameters, including; Respiration Rate (RR), Inhalation and Exhalation duration and ratio (I/E), as well as novel biomarkers. SG parameters are applicable to evaluate COPD patients' condition, or for monitoring patients with other respiratory conditions.~SG components are:~* RSM (Respiratory Sensing Module): non-invasive module with sensors that can detect the exhaled humidity and condensation. The RSM is a non-sterile, disposable, single patient use.~* ECU (Electronic Control Unit): a re-usable, wireless data acquisition and transmission unit. The ECU is connected to the RSM during the measurement and transmits the data via Bluetooth to the SG software.~* SenseGuard™ Software: for data management, acquisition, processing, logging and presentation of the digital respiratory signals.
Study NCT06379503 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HEART YOGA
Description: Heart yoga; It includes regular, balanced, safe light physical exercises, breathing exercises that provide breathing control, and meditation practices that include relaxation techniques.
Study NCT06379503 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: routine nursing care
Description: Basic nursing care after heart surgery
Study NCT05165004 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kangaroo Mother Care
Description: the preterm neonate was carefully put naked except for the head and diaper area on the mothers' bare chest with flexed arms and legs as in froglike position, and the head was turned sideways. The researchers wrapped and secured the mother's gown and put a blanket on the neonates' back to ensure neonatal thermal insulation
Study NCT05165004 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hammock Positioning
Description: After one hour of feeding, the preterm neonate was placed in a supine fetal position in the hammock where the head was supported in a neutral midline position by using rolled towel without neck hyperflexion or hyperextension. Moreover, the spine of the preterm neonate was supported while arms and knees were flexed
Study NCT05165004 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine Care of NICU
Description: ; encircling the neonate in a fetal position using rolled towel inside the incubator.
Study NCT03398252 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxazosin XL
Description: Participants will be randomized to receive increasing doses of doxazosin XL (0, 4, and 8 mg).
Study NCT03398252 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be randomized to receive a placebo for doxazosin XL.
Study NCT06463249 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Extended Helpline
Description: Those who achieved 2% weight loss at 2-month, will continue to Extended Helpline, where the participants can continue receiving all CORE resources including1-on-1 coaching through 1 optional participant-initiated call per month for 6 months.
Study NCT06463249 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Helpline
Description: Those who do not reach 2% weight loss at the end of 2 months will be randomized. Participants will continue to receive all CORE resources plus 1 optional participant-initiated call/month for 6 months. Additionally, the participants will receive 2 individualized coach-scripted feedback emails per month, and the option to receive daily text message reminders.
Study NCT06463249 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive Helpline
Description: Those who do not reach 2% weight loss at the end of 2 months will be randomized. Participants will continue to receive all CORE resources plus 2 scheduled coaching calls/month for 6 months. Additionally, the participants will receive 2 individual coach-scripted feedback emails per month, and the option to receive daily text message reminders.
Study NCT05519124 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785-7
Description: Treatment with the BTL-785-7 applicator to the BTL-785F system.
Study NCT05002036 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Trium eyedrops
Description: given three times daily from day 1 after surgery to end of Week 4
Study NCT05135468 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CU-40102 Spray
Description: topical application, 1\~4 sprays each time, once daily
Study NCT05135468 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CU-40102 Spray
Description: topical application, 1\~4 sprays each time, once daily
Study NCT05046236 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interactive POWER rehabilitation
Description: Interactive POWER rehabilitation training for twice a week, total 12 weeks, that consisted of 6 types of equipment for strength training.
Study NCT05046236 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventical physical training
Description: Conventional physical training models in current clinical use for twice a week, total 12 weeks, that consisted of strength training, balance training, stretching, gait training, and etc.
Study NCT04247321 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Licox® Brain Tissue Oxygen Monitoring System
Description: Invasive brain tissue oxygenation monitoring
Study NCT04247321 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-infrared spectroscopy (NIRS)
Description: Non-invasive approach to monitoring brain tissue oxygenation which uses two wavelengths of near infrared light and takes measurements of the ratio of oxyhemoglobin to total hemoglobin
Study NCT06353867 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group Exercise
Description: The children with special needs included in the study were included in group exercises for 45 minutes 2 days a week in groups of 10 children each. Group exercises were planned as balance and coordination exercises including warm-up and cool-down periods. In the warm-up and cool-down periods, counting in place and balance exercises were performed. The exercises included tasks such as side walking, tandem walking, walking on a balance board, walking in a figure 8, walking over obstacles, throwing a ball to the person next to him/her while passing through cones, and throwing a ball by jumping while passing through cones.The exercises were made more difficult by following a progressive method every 2 weeks. The exercises were performed in 3 sets of 5 repetitions under the supervision of a physiotherapist.
Study NCT05724147 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mandala Activity
Description: Three sessions of mandala activity, once a week, will be applied to the participants from the elderly people in the nursing home included in the study. The mandala activity planned to be done with the group will be done in addition to the standard monitoring applied in the institution, so it will be held at an appropriate time according to the flow in the institution. Before leaving the individuals, the most appropriate time for the next mandala session will be determined by taking into account the preferences of the individuals. Individuals to be included in the study will be grouped in groups of 10. Mandala activity application time is planned to last approximately 2 hours. If individuals have any physical symptoms, the time of the mandala activity is rescheduled, and each individual is expected to attend five sessions during the total study period.
Study NCT05678504 — intervention group
Intervention type: DEVICE
Intervention: The phlebotomy procedure
Description: The process of blood collection with a vascular imaging device
Study NCT05151562 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Music Therapy
Description: Each study participant will receive two 30-minute live synchronous virtual music therapy sessions per week for a period of 8 weeks to be delivered by a board-certified music therapist (using Zoom as a primary platform). These individualized therapeutic encounters will use music that is personally meaningful and familiar to the participant and the participant's loved ones to facilitate reminiscence. Decision-making processes made by the music therapist will reflect a flexible session structure and series of intervention choices contingent on each participant's cultural identity, expressive and receptive communication, fine and gross motor ability, affect, orientation to time and place, and personal preferences on any given day.
Study NCT04703335 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antimicrobial efficacy of gel ZHCK4 as a patient preoperative skin preparation
Description: Evaluate the antimicrobial efficacy of two concentrations of one patient preoperative skin preparation product compared to a positive control (2.0% chlorhexidine gluconate) and negative control (physiological saline 0.9% solution). Following a 14-day restriction period, subjects will be sampled for baseline, 10-minutes, 6-hours, and 24-hours microbial reduction evaluations post-product application. Subjects will not be sequestered for the 6-hour or 24-hour evaluations. Test day baseline criteria will be set at: abdomen: ≥ 3.0 log10 CFU/cm2, and inguen: ≥ 5.0 log10 CFU/cm2.
Study NCT05854082 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Lidocaine 2% Polyampoule
Description: Three intervention conditions in a repeated measures design - lidocaine; no perturbation, candy (lollipop)
Study NCT05535270 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Oxford Depression Questionnaire (ODQ)
Description: The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of emotional blunting: not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .
Study NCT06322108 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botensilimab + Balstilimab
Description: Botensilimab is a fragment crystallizable (Fc)-engineered human immunoglobulin G1 (IgG1) monoclonal antibody that targets cytotoxic T lymphocyte-associated protein 4 (CTLA-4). Balstilimab is a human monoclonal antibody that targets programmed cell death protein 1 (PD-1).
Study NCT05371275 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Description: 125 mg of palbociclib once daily for 21 consecutive days
Study NCT05813860 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azathioprine
Description: azathioprine in combination with Infliximab, with a dose of 1-2 mg/kg/d.
Study NCT05813860 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Infliximab
Description: 5mg/kg for the first dose, and the same dose at weeks 2 and 6 after the first dose and every 8 weeks thereafter. Treatment with single Infliximab or combined azathioprine, respectively.
Study NCT05813860 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Infliximab
Description: 5mg/kg for the first dose, and the same dose at weeks 2 and 6 after the first dose and every 8 weeks thereafter. Treatment with single Infliximab or combined azathioprine, respectively.
Study NCT04743869 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kyphos FS™ Bone Substitute
Description: Dorsal instrumentation via Longitude II (Medtronic Austria GmbH/Vienna) and balloon kyphoplasty are performed. KyphOs FS™ bone cement will be introduced in the fractured vertebral body.
Study NCT04743869 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: KYPHON ActivOs® Bone Cement with Hydroxyapatite
Description: Dorsal instrumentation via Longitude II (Medtronic Austria GmbH/Vienna) and balloon kyphoplasty are performed. KYPHON ActivOs® Bone Cement with Hydroxyapatite will be introduced in the fractured vertebral body.
Study NCT05762965 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GOS 1
Description: 1 sachet each morning
Study NCT05762965 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: GOS 2
Description: 1 sachet each morning
Study NCT04800575 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: semi-permeable film
Description: Experiment group use semi-permeable film as dressing in exit-site of CVC and dressings will be changed per hemodialysis session, or or whenever the dressing is soiled, bloody, or fell off.
Study NCT04800575 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: sterile gauze and tape
Description: Control group use sterile gauze and tape as dressing in exit-site of CVC and dressings will be changed per hemodialysis session, or whenever the dressing is soiled, bloody, or fell off.
Study NCT03683095 — intervention group
Intervention type: PROCEDURE
Intervention: Lymphovenous bypass
Description: Lymphovenous bypass will be performed under general anesthetic. Indocyanine green lymphangiography will be performed by injecting indocyanine green into each finger / toe web of the lymphedematous limb and mapping the lymphatic system with the NOVADAQ SPY Fluorescence Imaging (Mississauga, Canada).~Subdermal dissection of lymphatics and venules will be carried out under a surgical microscope. Lymphatic vessels will be anastomosed to adjacent recipient venules to create the bypass between the lymphatic and the venous systems. In total, 1-5 anastomoses will be performed. This will require 1-5 incisions, each with a length of 2-3 cm.~Postoperatively, the limb will be wrapped loosely with compression bandages. No special postoperative monitoring is required.~The surgery will be performed on an outpatient basis with no planned hospital stay.
Study NCT06218628 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talazoparib
Description: pacritinib in combination with talazoparib
Study NCT06218628 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pacritinib
Description: pacritinib in combination with talazoparib
Study NCT04686929 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abatacept s.c.
Description: subcutaneous abatacept: 250mg (d-1) , 125mg (d+5, +14, +21, +28, +35, +42, +49, +56) combined with CsA, MTX, MMF.
Study NCT06009406 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physiotherapy
Description: This group will be applied to the soleus, gastrocnemius muscle and Achilles tendon with Graston, an instrumental myofascial mobilization technique, until they feel warmth in the skin and tonus relaxation in the target muscles. The control group will be subjected to 3 repetitions of passive stretching for 30 seconds for the same structures.