AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04417894 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dupilumab
Description: Solution for subcutaneous (SC) injection administration
Study NCT04417894 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Solution for SC injection administration
Study NCT05347160 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biodentine
Description: using of biodentine , calcium hydroxide and platelet rich fibrin as pulpotomy agents
Study NCT06017804 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle energy technique
Description: Participants were required to adopt a supine position. MET's post-isometric relaxation method was chosen. The therapist gently flexed the patient's hip until the limitation bar-rier was detected. At this stage, isometric contractions against resistance were applied. After that, the patients were told to resist the movement with only 25% of their strength. Before the leg was released, the contraction was maintained for 7-10 seconds. On exhale, the knee joint was straightened (extended) towards its new barrier, and a stretch was applied and maintained through that barrier for 30 seconds. This procedure was carried out six times.
Study NCT06017804 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self-myofascial release technique
Description: A foam roller was rolled from the ischial tuberosity to the back of the knee on the side being tested while the participant remained seated in a long sitting position. Individuals were instructed to keep all of their body weight on the leg being evaluated. They spent 30-40 seconds rolling one hamstring at a time in each set (10 times back and forth).
Study NCT05448911 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraoperative navigation combined with Catheter screw technique
Description: It uses minimally invasive small incisions, physiological access to the pelvis, and hollow screws for Pelvic and Acetabular fractures
Study NCT05448911 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Open reduction and internal fixation with steel plate
Description: Open reduction and plate internal fixation is the most commonly used method to treat pelvic fracture, which can achieve anatomical reduction and rigid fixation. However, this method requires extensive dissection of the surrounding soft-tissue fracture and is invasive
Study NCT06144905 — intervention group
Intervention type: OTHER
Intervention: standard care treatment program
Description: The standard care treatment consists of a program of psychotherapy and nutritional rehabilitation to achieve normalization of food-intake and weight gain.
Study NCT06017596 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PEEK framework
Description: All-on-4 implants with PEEK framework of fixed detachable prosthesis
Study NCT05185271 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dyad-focused strategy training
Description: Rehabilitation therapists will be hired to deliver the intervention to the stroke survivors-caregiver dyads on a one-to-two base. The therapist will ask the dyad to identify their shared goals and provide them the global strategy Goal-Plan-Do-Check (also called guided discovery strategy), which involves (1) setting a goal to address the barriers, (2) developing a plan to address the goal, (3) doing the plan, and (4) checking if the plan worked or required revising. This procedure will be repeated iteratively until the dyad's goal is met, and the next goal can be moved on to.
Study NCT04011020 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Stem Cell Educator therapy
Description: Patients with T1D will be evaluated by the study principal investigator or co-investigators. Informed consent will be obtained at the initial screening visit. The initial screening visit will occur within 30 days of initiation of SCE therapy. The second screening visit will occur within 7 days of therapy. Subjects who meet all criteria will be scheduled for treatment. All enrolled subjects will receive treatment with the SCE system consisting of a single session of mononuclear cells (MNC) collection by apheresis where 10 L of blood will be processed on day -1. The MNC product will then be exposed over to the SCE and on day 0 the product will be infused intravenously back to the patient.
Study NCT04607200 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN2034
Description: Anti-PD-1 Monoclonal Antibody
Study NCT04607200 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1884
Description: Anti-CTLA-4 Monoclonal Antibody
Study NCT05903846 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oketani massage
Description: The part between the breast and the base of the lower pectoral muscle is called the oketani. It is a manual massage technique developed to encourage breastfeeding in breastfeeding problems such as insufficient milk production and mastitis. It is a massage that stimulates the breast, relaxes it and is painless.
Study NCT06463600 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magseed
Description: Tumour localizer
Study NCT06463600 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Metallic clip and guide wire
Description: Tumour localizers
Study NCT06339528 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vojta's Reflex Locomotion
Description: Reflex locomotion according to Vojta's therapy is a neurorehabilitative concept originally used for diagnostics and treatment of infants who were at risk of non-physiological psychomotor development, especially spastic cerebral palsy. This concept utilizes stimulation of specific zones described by Vojta to evoke global motor and non-motor response.~Trigger zones are specific body zones that are stimulated with pressure during reflex locomotion stimulation. They are pressure stimulated in order to induce reflex response. Variations of stimulation of different trigger zones (spatial summation) causes multiplication of afferent impulses. Sufficiently long stimulation of trigger zones (temporal summation) induces isometric contraction in muscle groups described by Vojta.
Study NCT06339528 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham stimulation
Description: Control group received sham stimulation by physicians at zones outside of the pressure zones, specifically 4-5 cm above the patella and on the lateral malleolus.
Study NCT05170243 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 9MW1911 Injection
Description: Single dose intravenously on day 1
Study NCT05170243 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 9MW1911 Injection Placebo
Description: Single dose of matching placebo intravenously on day 1
Study NCT05021783 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pressure pain threshold
Description: The sacroiliac PPT scores will be obtained bilaterally from four measurement points; the first point is located 1 cm medially and caudally from spina iliaca posterior superior (SIPS) and 3 more laterally, medially and cranially.The left trapezius muscle will be used to evaluate distant control point .The 1 cm2 algometer probe will be placed vertically in the each selected point and pressure will be increased with 0.1 kg/sc until the participant reporting pressure became painful. The pressure value at which the pain is first felt will be accepted as the PPT of that point.
Study NCT05021783 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Central Sensitization Inventory
Description: Standardized questionnaire to determine the level of central sensitization
Study NCT05021783 — intervention group
Intervention type: OTHER
Intervention: Spondyloarthritis Research Consortium of Canada scoring system
Description: SPARCC scoring consists of two subcomponents to detect sacroiliitis activation and structural damage. In the short tau inversion recovery (STIR) sequence, 6 consecutive coronal sections will be examined and the signal increase will be scored as 0 = normal signal and 1 = increased signal. In this way, the maximum score can be 12 in a single coronal section. Evaluations Total maximum score of 72 in 6 consecutive coronal sections. In structural scoring, similar to sacroiliitis scoring, the SI joint is divided into four quadrants to evaluate whether there is fatty change, erosion, backfill and ankylosis. Each lesion is scored as 0=absent or 1=present. In this way, fatty change and erosion can be scored between 0-40 and backfill and ankylosis can be scored between 0-20 in 5 consecutive sections in total scoring.
Study NCT05021783 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Temporal Summation
Description: TS will be evaluated over the trapezius muscle and sacroiliac joints with manuel algometer. In the evaluation of TS, a pressure as much the PPT value of each point will be applied with pain pressure algometer ten times with a 1-second interstimulus interval. Patients will be asked to rate their pain using on a 0 to 10 visual analogue scale (VAS) at 0, 5, and 10 seconds. TS will be calculated by subtracting the rating at 0 seconds from the rating at 10 seconds. The point that is located 1 cm medially and caudally from SIPS was used for SI joint TS measurement on both sides.
Study NCT05021783 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Conditioned pain modulation
Description: First stimulus will be applied to trapezius with the pressure that induced a pain intensity of 4 point on a 10 point VAS as called a test stimulus. After that the right hand of the patient will be immersed in 7 Celsius water for 20 seconds to create a conditioning stimulus. Second test stimulus with the same intensity of first one will be applied to trapezius after the conditioning stimulus and patients will be asked to rate their pain. If the patients cannot hold their hand in the water for 20 seconds, the test stimulus will be applied immediately after the patients removed their hands out of water. The ratio between the first and second VAS values multiplied by 100 will be defined as CPM score
Study NCT04797065 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 6-minute then 9-minute withdrawal
Description: Patients in 6-minute then 9-minute withdrawal group will first be carefully observed in 2 minutes then in 3 minutes during each colonic segment.~In actual performance, withdrawal of the right colon, transverse colon and the left colon can be operated in segmental tandem colonoscopy. Taking the right colon as an example, after the endoscope reaches the cecum, it can be withdrawn to the splenic curvature in 2 minutes, then reentered the cecum and withdrawn to the splenic curvature in 3 minutes.
Study NCT04797065 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 9-minute then 6-minute withdrawal
Description: Patients in 9-minute then 6-minute withdrawal group will first be carefully observed in 3 minutes then in 2 minutes during each colonic segment.~In actual performance, withdrawal of the right colon, transverse colon and the left colon can be operated in segmental tandem colonoscopy. Taking the right colon as an example, after the endoscope reaches the cecum, it can be withdrawn to the splenic curvature in 3 minutes, then reentered the cecum and withdrawn to the splenic curvature in 2 minutes.
Study NCT04978207 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A Faithful Response to COVID-19
Description: See previous description
Study NCT04978207 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A Faithful Response to COVID-19
Description: See previous description
Study NCT06266143 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Y101D
Description: Intravenous infusion of Y101D at day1, combined with Gemcitabine and Nab-Paclitaxel IV infusion at day1, 8, a 21-day cycle. After 6 cycles, Y101D and Gemcitabine infusion is applied as the maintenance treatment.
Study NCT05450146 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Partner in Balance
Description: The Partner in Balance intervention (Boots, 2018) consists of 1) a face-to-face intake session with a care professional (casemanagers, dementia nurses or district nurses) to familiarize participants with the program, set goals, and select preferred module themes; 2) tailored online thematic modules, including psychoeducation, behavioral modeling, reflective assignments, set goals, and online messaging feedback with the care professional over 8 weeks; and 3) a face-to-face evaluation session with the care professional evaluating previously set goals.
Study NCT05954442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: Everolimus is a kind of mTOR inhibitors which has been approved to use in several kinds of cancers, especially in metastatic breast cancer .
Study NCT05954442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Investigator's Choice of Chemotherapy
Description: Investigator's choice of chemotherapy means the chemotherapy chosen by investigators/doctors to treat metastatic triple negative breast cancer, including nab-paclitaxel, capecitabine, eribulin, carboplatin, vinorelbine, or utidelone.
Study NCT05954442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Investigator's Choice of Chemotherapy
Description: Investigator's choice of chemotherapy means the chemotherapy chosen by investigators/doctors to treat metastatic triple negative breast cancer, including nab-paclitaxel, capecitabine, eribulin, carboplatin, vinorelbine, or utidelone.
Study NCT05157815 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soluble Fibre
Description: 10g soluble corn fibre to be consumed twice per day
Study NCT05157815 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Calorie Matched Control
Description: 2g maltodextrin consumed twice per day
Study NCT06241040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Exercises with core Muscle strengthening
Description: Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.
Study NCT06241040 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise without Core Muscle Strengthening
Description: Aerobic Exercise without Core Muscle Strengthening
Study NCT05183750 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: High tibial osteotomy
Description: Opening wedge high tibial osteotomy will be done according to the measurement preoperatively and fixation will be by plate and screws.
Study NCT04770051 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous inferior cervical sympathetic block
Description: The procedure will be performed while the patient was awake and under fluoroscopic guidance. A total of 3 ml of 1% lidocaine will be infiltrated to anesthetize the skin and subcutaneous tissues down to the left common carotid artery. A 22 gauge × 3.5 inch BD™ Quincke spinal needle will be introduced at the level of the body of the sixth cervical vertebra, medial to the left common carotid artery. The needle will be advanced until it reached the junction between the body and transverse process of the sixth cervical vertebra. Contrast injection will be used to demonstrate the position of the needle anterior to the paravertebral muscles, with spread along the axis of the interfascial compartment (Figure 1). A total of 20 ml of 0.25% bupivacaine (Marcaine, Hospira, Lake Forest, IL) will be injected over 10 min through the needle. The effectiveness of sympathetic blockade will be confirmed by postprocedure development of ptosis and miosis in the left eye.
Study NCT05442307 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asthma education
Description: A 15 minutes (preferable) one-on-one educational visit about asthma treatment. The main points being: Every person with asthma should be treated with inhaled corticosteroids (ICS). Most patients with asthma should be treated with Bufomix Easyhaler either as needed and/or regularly. Patients should not use short-acting bega2-agonist (SABA) unless they use a medium-ICS-dosis.
Study NCT05442307 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Other education
Description: A 15 minutes (preferable) one-on-one educational visit about another topic (NOT asthma).
Study NCT05275907 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amlodipine Besylate
Description: 10 mg capsule once daily for 6 weeks
Study NCT05275907 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chlorthalidone
Description: 25mg capsule once daily for 6 weeks
Study NCT06149780 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Patients treated with laser
Description: Patients treated with laser with topical steroid Patients treated with laser with vehicle
Study NCT05332158 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires to report barriers to medication adherence
Description: One questionnaire specific to DOACs and one specific to statins have been integrated within the medical records system and will be sent to eligible patients to respond to following written informed consent.
Study NCT05266235 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Validation of the Withings bodyscan scale WBS08
Description: Participants will undergo simultaneous recordings of ECGs with the comparator and the study device
Study NCT05492929 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The deep breathing group
Description: The deep breathing group
Study NCT05492929 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 4-7-8 breathing technique
Description: 4-7-8 breathing technique Group
Study NCT05712044 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Folic Acid 5 MG
Description: Folic acid 5mg tablets will be administered orally every 8 hours then samples from buccal mucosa will be taken 15 days and 30 days after suplementation.
Study NCT04710342 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CapBuster
Description: Evaluate the safety and effectiveness of the CapBuster System in crossing de novo or restenotic chronic total occlusions in infrapopliteal peripheral arteries.
Study NCT03678480 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HTD1801
Description: HTD1801 capsules, 250mg
Study NCT03678480 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ursodeoxycholic Acid
Description: UDCA capsules, 125mg
Study NCT05186207 — intervention group
Intervention type: OTHER
Intervention: abnormal pre-pregnancy test results that need clinical intervention
Description: The patients who need clinical intervention before or after pregnancy were divided into observation group. Doctors will formulate a personalized treatment plan according to the international guidelines. Researchers wouldn't interfere with the expert diagnosis and treatment process.
Study NCT05459831 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: QDot Micro Catheter
Description: Atrial fibrillation radiofrequency ablation with 90W or 50W energy setting.
Study NCT04210609 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vaporous Hyperoxia Therapy
Description: 55 minutes of treatment, 2 times per week
Study NCT05748093 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cobicistat
Description: Feasibility of pharmacokinetic boosting using cobicistat for personalized treatment strategies for osimertinib.
Study NCT05661773 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: the combined use of vacuum assisted suction and heat exchanger warming
Description: Heat causes capillary vasodilation, where warming hands and toes improves blood flow while cooling them causes vasoconstriction. Applying a vacuum across a capillary bed increases the transcapillary gradient increasing the driving force of blood flow into tissues. The combination of these two mechanisms can work synchronously to improve blood flow to ischemic extremities and digits.
Study NCT06471868 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IY-HCR21
Description: Betanechol 50mg
Study NCT06471868 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IY-MIC
Description: Betanechol 25mg
Study NCT04002011 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Warfarin
Description: It will be started on postoperative day 1 or later when oral anticoagulation is secondary indicated. Daily dose will be adapted to obtain an international normalized ratio of \[2.0-3.0\]. Other anticoagulants will be not administrated.
Study NCT04002011 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dabigatran
Description: It will be started when patients will be discharged from our center. Our pharmacist referent will validated the drug and its daily dose. Other anticoagulants will be not administrated.
Study NCT04002011 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivaroxaban
Description: It will be started when patients will be discharged from our center. Our pharmacist referent will validated the drug and its daily dose. Other anticoagulants will be not administrated.
Study NCT04002011 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Apixaban
Description: It will be started when patients will be discharged from our center. Our pharmacist referent will validated the drug and its daily dose. Other anticoagulants will be not administrated.
Study NCT04002011 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Edoxaban
Description: It will be started when patients will be discharged from our center. Our pharmacist referent will validated the drug and its daily dose. Other anticoagulants will be not administrated.
Study NCT05766995 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Waterpik Water Flosser
Description: A pulsating water flosser and jet tip designed to clean between the teeth and below the gingival margin.
Study NCT05766995 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oral-B Water Flosser
Description: A water flosser and specialized tip that delivers water with microbubbles of air
Study NCT05766995 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Waxed Dental Floss
Description: Nylon string used to clean between the teeth manually