AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05842161 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment as Usual
Description: Standard treatment for HIV/TB with one session of psychoeducation.
Study NCT01796405 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clofarabine
Study NCT04818593 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ZyMot Multi Sperm Separation Device (850 ul)
Description: 850 uL of untreated semen will be directly deposited into the inlet port of the ZyMotTM Multi device, followed by placement of 750 uL culture medium in the outlet port and throughout the upper collection chamber. The device will then be incubated in a humidified 37C CO2 incubator for 30 minutes. During incubation, the healthiest and most motile sperm will swim through the microporous filter and into the upper collection chamber, where they will be recovered via the outlet port. 500 uL of the sperm sample will be removed and placed in a separate tube for analysis and insemination.
Study NCT04818593 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Density Gradient Centrifugation
Description: Density gradient centrifugation will be performed using a one-layer preparation of 90% Isolate in 15 mL conical tubes. Semen will be layered over 1 mL of gradient and then centrifuged for 15 min at 300xg. The supernatant will be removed and discarded. The sperm pellet will be washed by mixing with Multipurpose Handling Medium Complete and centrifuging the sample for 5 min at 400xg. After the wash, the supernatant is removed and discarded and the pellet is re-suspended in culture medium, assessed for sperm parameters, and held at room temperature until insemination.
Study NCT05297981 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: The patient will be placed in lateral decubitus position. A high frequency linear probe of a transportable Fuji M-Turbo ultrasound system will be placed on the spinous process at T8 level on the parasagittal plane and then slide 2.5-3 cm laterally to visualize the transverse process and erector spinae muscle. Using the inplane technique,then 0.5 ml/kg of 0.25% bupivacaine will be injected between the muscle and transverse process. The same procedure will be performed bilaterally.
Study NCT05297981 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Quadratus lumborum block
Description: The patient will be placed in the lateral decubitus position. A low frequency curved probe of a transportable Fuji M-Turbo ultrasound system will be placed horizontally in the anterior axillary line midway between the subcostal margin and the iliac crest to identify the triple abdominal muscle layers.A 22-G, 80-mm needle echogenic needle will be inserted in plane relative to the US probe, into the posterior aspect of the QL muscle (between QL and erector spinae muscle); this is known as QLB type 2. Then, 0.5 ml/kg of 0.25% bupivacaine will be injected behind the muscle as a bolus dose. The block will be performed bilaterally.
Study NCT06539923 — intervention group
Intervention type: OTHER
Intervention: retrieving data
Description: Data will be retrieved retrospectively
Study NCT06446440 — intervention group
Intervention type: PROCEDURE
Intervention: Laparoscopic adhesiolysis
Description: Laparoscopic adhesiolysis
Study NCT06446440 — intervention group
Intervention type: PROCEDURE
Intervention: Open adhesiolysis
Description: Open adhesiolysis
Study NCT06300658 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: Patient will receive preemptive stellate ganglion block (SGB) just before spinal anesthesia.
Study NCT05182957 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 monoclonal antibody
Description: Anti-PD-1 monoclonal antibody, 200mg i.v d1 (/21d)
Study NCT05182957 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide 25mg qd po d1-d10 (/21d)
Study NCT05182957 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Azacitidine 75mg/m2 i.v d1-d7 (/21d)
Study NCT04956159 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
Description: rTMS is a non-invasive procedure in which cerebral electrical activity is influenced by a rapidly changing magnetic field. The magnetic field is created by a plastic-encased coil which is placed over the patient's scalp. The magnetic field can be directed onto specific areas of the brain. rTMS can modulate cerebral activity by low or high frequencies. Over time, the magnetic field pulses can gradually change the activity level of the stimulated brain region and help symptoms of depression and anxiety.
Study NCT04956159 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham rTMS
Description: Sham rTMS involves a click replicating the sound of the magnetic discharge, without any magnetic pulse being delivered.
Study NCT06116825 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1450ppm Fluoride toothpaste
Description: 1450ppm Fluoride toothpaste
Study NCT06116825 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 1000Pppm Fluoride toothpaste
Description: 1000Pppm Fluoride toothpaste
Study NCT05073809 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Photoacoustic Imaging Scan
Description: A relatively novel modality that combines exquisite spatial resolution with the ability to image multiple biological tissues, including blood, water and lipid.
Study NCT04806607 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 19G FNB
Description: Biopsy specimen adequacy using the 19G FNB
Study NCT04806607 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 22G FNB
Description: Biopsy specimen adequacy using the 22G FNB.
Study NCT06263569 — intervention group
Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Unilateral primary total hip arthroplasty procedure.
Study NCT04590092 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cooper Surgical Ring Pessary with Incontinence Knob
Description: A pessary is a silicone ring with a knob that in inserted into the vagina to treat urinary incontinence by providing urethral support.
Study NCT06367881 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alveofact
Description: Intratracheal High-dose Alveofact versus Low-dose Alveofact with or without Budesonide
Study NCT06367881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alveofact
Description: Intratracheal High-dose Alveofact versus Low-dose Alveofact with or without Budesonide
Study NCT06367881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Budesonide
Description: Budesonide
Study NCT05619198 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High Intensity Interval Exercise
Description: High Intensity Interval Exercise:~* 5 minutes resting phase @ 0 watts.~* 5-minute warm up phase @ 20 watts.~* 40 minutes of interval work consisting of eight bouts of 1-minute cycling at a power output corresponding to \~85% of VO2max interspersed with 4-minute recovery periods at 20 watts.~* 5 minutes resting phase @ 0 watts.
Study NCT05619198 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Moderate Intensity Continous Exercise
Description: Moderate Intensity Continous Exercise:~* 5 minutes resting phase @ 0 watts.~* 5-minute warm up phase @ 20 watts.~* 40 minutes of MICE 65% VO2max.~* 5 minutes resting phase @ 0 watts.
Study NCT06047691 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Abbreviated, Intensive, Multi-Couple Group Cognitive-Behavioral Conjoint Therapy for PTSD
Description: Approximately 12 hours of programming delivered over 2 consecutive days in a multi-couple group retreat format. Couples are provided with psychoeducation about PTSD and relationship functioning and are taught cognitive and behavioral skills to address the manifestation of PTSD in the couple relationship. Couples will also meet once individually with one of the group leaders 1-2 weeks before the retreat and once 1-2 weeks after the retreat.
Study NCT06047691 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevention and Relationship Education Program
Description: Approximately 12 hours of programming delivered over 2 consecutive days in a multi-couple group retreat format.The content of PREP and workshop experiences focuses on helping couples communicate effectively, manage conflict without harming their relationship, preserve and act on commitment, improve relationship decision-making, increase understanding of differences between partners, and protect positive connections between partners. Approximately 12 hours of PREP content will be delivered over 2 consecutive days in a multi-couple group retreat format. Couples will also meet once individually with one of the group leaders 1-2 weeks before the retreat and will check in with a member of the study staff 1-2 weeks after the retreat.
Study NCT05578729 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Single surgical mask group, Double surgical mask group, N95 mask group
Description: Masks were given to the resting pregnant women 30 minutes before the NST, and they were provided to wear masks. After 30 minutes, the vital signs of the pregnant women were measured just before and after the NST, and the images of the NST traces were taken.
Study NCT05996172 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CAMS Single Session Consultation
Description: CAMS is a clinical intervention designed to modify how clinicians engage, assess and plan treatment with suicidal patients. The foundational brief intervention that all participants will receive includes 1 90-minute session of CAMS assessment and planning interview with follow-up care navigation. CAMS is based around a model of STB which states that youth become suicidal in response to overwhelming pain, and treatment identifies and targets the drivers of suicide as the primary focus of assessment and intervention.
Study NCT05996172 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Driver Focused Skills Training
Description: The CAMS approach focuses on therapeutic assessment, collaborative identification and treatment of the patient-defined STB drivers (i.e., the problems that make suicide compelling to the patient) and utilizes problem-focused treatment sessions to address the drivers in order to reduce the wish to die. In the SOARS brief intervention model, specific skills are taught to youth based on CAMS drivers/case conceptualization of suicidality.
Study NCT05996172 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Caregiver Skills Training
Description: Caregivers will receive 3, 30-minute modules across 3 sessions that provide explicit coaching in several skills adapted from evidence-based treatments for youth suicidality including DBT and CBT.48,49 Module content will include 1) psychoeducation on suicidality and the escalation cycle and creation of a communication plan related to responding to youth suicidality (i.e., Crisis Escalation and Communication Plan); 2) positive communication and relationship building strategies including reflective listening, validation, and how to implement regular teen-directed one-on-one time; and 3) setting up behavioral expectations, house rules, and using positive reinforcement based contingency management in the home (i.e., targeted praise, using rewards to promote more effective behaviors). All modules will include didactic skill building, role-play of skill use with the therapist, and a check-in with the youth and youth therapist to collaboratively problem-solve barriers to use of skills.
Study NCT05996172 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lethal Means Safety
Description: The CAMS Therapeutic Assessment incorporates low levels of lethal means restriction (see above). Experimental Intervention Component 4 will provide a high level of lethal means restriction that includes the evaluation of the need for a lock box, the provision of a lock box if needed, structured process for evaluating home safety in each room of the house, specific directives to accomplish, follow up with the clinician, and problem-solving barriers to lethal means safety over two, 30-minute modules delivered across 2 sessions.
Study NCT04799392 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NOWDx COVID-19 Test
Description: The investigational device is the NOWDx COVID-19 Test.
Study NCT05581914 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MY LIFE treatment
Description: The MY LIFE is a group treatment consisting of 5 workshops, for adolescents with a low motivation for mental health treatment. It aims to increase self- worth, hope for the future and seeking social support through exercises by using music and lyrics and other creative exercises to engage adolescents. The MY LIFE treatment also uses methods that stem from psychodynamic, cognitive behavioral, and solution focused theories. The therapeutic attitude is based on client-centered therapy of Rogers, which includes a genuine, positive regard and empathic understanding, focusing on the inner strength and growth potential of a person. Adolescents are never forced to participate during the workshops, merely encouraged.~The core of the treatment is: the adolescent decides
Study NCT05581914 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care as Usual
Description: The care as usual the adolescents receives
Study NCT06288087 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: VR Based Training with Machine Guidance (MG Group)
Description: The members of both groups will undertake a VR based basic training for ALS. Afterwards MG group were trained with VR based Advanced Training Module, which provides training with full machine guidance. The knowledge level will then be evaluated by the exam mode of the VR based training module
Study NCT06288087 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: VR Based Training with Educator Guidance in Metaverse (EG Group)
Description: The members of both groupswill undertake a VR based basic training for ALS. Afterwards EG group will attend at VR based Educator guided training in metaverse. The knowledge level will then be evaluated by the exam mode of the VR based training module
Study NCT05951608 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK127 in combination with AK112
Description: AK127 in combination with AK112 (administered on Day 1 of each cycle, Q3W) up to 2 years
Study NCT05865678 — intervention group
Intervention type: OTHER
Intervention: Not an intervention study
Description: This is a study administering questionnaire and interviews using mixed quantitative and qualitative methodology with the aim to describe and evaluate musculoskeletal health of adult haematological cancer survivors and its impact to survivors.
Study NCT05209100 — intervention group
Intervention type: PROCEDURE
Intervention: Sigmoidoscopy
Description: During the sigmoidoscopy, biopsy tissue will be obtained for research purposes. Biopsies will be performed based on typical standard of care procedures without an antecedent bowel prep.
Study NCT06318910 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: orthotic wedge
Description: The orthotic wedges with a full length of 3-mm soft foam layer will be provided to each participant under the molded orthoses; the amount of wedge angle will depend on the rearfoot and forefoot angles of the participants. The present study developed 3-degree, 6-degree, and 8-degree wedges for the rearfoot and forefoot. It was made from solid rubber with a cover of thin fabric. There are three sizes for these products which include small (S), medium (M), and large (L) sizes, according to the foot length of participants.
Study NCT06318910 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CFO
Description: The 3-quarter-length CFO will be made from thermoplastic material (rigid foot orthoses) which consists of four layers i.e. two layers of 0.5-mm polyvinyl chloride (PVC), one layer of 1.5-mm thick fiber to increase strength of foot orthoses in the bottom layers as well as one layer of 1.2-mm genuine leather in the upper layer to increase comfort. It incorporates a heat-molding process to adjust individual foot shape in prone position. The materials will be set within approximately three minutes.
Study NCT06318910 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CFO
Description: The 3-quarter-length CFO will be made from thermoplastic material (rigid foot orthoses) which consists of four layers i.e. two layers of 0.5-mm polyvinyl chloride (PVC), one layer of 1.5-mm thick fiber to increase strength of foot orthoses in the bottom layers as well as one layer of 1.2-mm genuine leather in the upper layer to increase comfort. It incorporates a heat-molding process to adjust individual foot shape in prone position. The materials will be set within approximately three minutes.
Study NCT06484790 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NW-301V
Description: TCR-T T cell targeting KRAS G12V mutation
Study NCT06484790 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NW-301D
Description: TCR-T T cell targeting KRAS G12D mutation
Study NCT04603573 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride )
Description: 5% Sodium Fluoride Varnish is a fluoride varnish which is applied to tooth surfaces for sealing dentinal tubules and treatment of hypersensitive teeth. The varnish is applied in a thin layer over the tooth with an applicator brush, and moisture from saliva cures the varnish for adhesion to the tooth surface.
Study NCT04603573 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Resin based fissure sealant (3M Clinpro sealant )
Description: teeth will be isolated with coton rolls and saliva ejector then etching for pits and fissure then tooth will be washed then apply resin based fissure sealant on occlusal surface.~resin fissure sealant is a more sensitive for saliva.
Study NCT04734912 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: gastroscopy in transnasal techique
Description: All patients with indication for gastroscopy in transnasal technique are included.
Study NCT05008107 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: Using VR goggles to watch peri-operative instructional video.
Study NCT05550311 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Robot-assisted rehabilitation
Description: In addition to conventional treatment, an upper extremity robot-assisted rehabilitation program. Range of motion exercises will display on the monitor as a game form. There are 4 games available on the computer (airplane game, rabbit shooting game, ball game, and shopping game) and these games can provide exercises for three joints (shoulder, elbow wrist). There are also 3 different levels of resistance apparatus for each joint. People with a full range of motion can do these exercises with resistance. Before starting the rehabilitation, which joint and which movement to do is determined. To the person; After explaining the desired movement and how to play the game shown on the monitor, the exercises are started. The exercises last 45 minutes, during which exercises are performed for the shoulder, elbow, and wrist.
Study NCT05550311 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation
Description: The conventional Rehabilitation Program consists of; range of motion exercises, strengthening exercises, stretching exercises, balance, and walking exercises and Bobath based neurophysiological approaches.
Study NCT05550311 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional rehabilitation
Description: The conventional Rehabilitation Program consists of; range of motion exercises, strengthening exercises, stretching exercises, balance, and walking exercises and Bobath based neurophysiological approaches.
Study NCT06110130 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Empagliflozin 10 MG
Description: Take Empagliflozin 10 mg orally daily for 4 months
Study NCT06110130 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Take Placebo 10 mg orally daily for 4 months
Study NCT04804254 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-623
Description: Oral Tablets
Study NCT04804254 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-992
Description: Oral Tablets
Study NCT04608812 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OS2966
Description: OS2966 is a humanized monoclonal antibody antagonizing CD29 (Beta 1 integrin)
Study NCT04608812 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gadoteridol
Description: Gadoteridol is a contrast agent which will be added to OS2966 to allow investigators to observe how OS2966 distributes within the brain tumor. Gadoteridol is approved by the FDA for intravenous injection during an MRI scan. It is not approved by the FDA for administration directly into a tumor.
Study NCT03824847 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clarithromycin 250 MG
Description: Clarithromycin 1 tablet (250mg) twice daily for three days
Study NCT03824847 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebos
Description: Placebo group: (identical-looking) placebo 1 tablet twice daily for three days
Study NCT05841043 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8028 eye drops
Description: SHR8028 eye drops
Study NCT05841043 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle eye drops.
Description: Vehicle eye drops.
Study NCT04469296 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: iso-caloric ketogenic diet
Description: Each patient will be offered a daily diet plan that includes the different groups of low glycemic index foods to bring to each meal and snack, with the notion of quantity. Carbohydrate-free foods can be consumed ad libitum. Dietary advice will be given to increase the consumption of lipid foods (vegetable oils, butter, cheeses, fatty fish, etc.) so that 65% of the total energy intake is provided by lipids. In addition, a list of unauthorized sugars and sweeteners substitutes will be proposed as well as a low glycemic index food composition table centered on carbohydrates for better control of food choice