AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05524740 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785-7
Description: Treatment with the BTL-785F device with the BTL-785-7 applicator for improvement of the structure of facial muscles.
Study NCT06303947 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube
Description: The group was given enteral nutritional support with Intermittent Oro-esophageal Tube according to the following procedure: Before each feeding, inside and outside of the tube was cleaned with water. During feeding, the patient should maintain a semi-reclining or sitting position with mouth opened, and the tube was inserted slowly and smoothly into the upper part of the esophagus by medical staffs while the appropriate depth of intubation was checked with the calibration markings on the tube wall. The distance from the incisors to the head part of the tube should be between 22-25 cm. However, the specific depth should be evaluated based on patients' feedback and adjusted accordingly. After insertion, the tail part of the tube should be put into a container full of water and the absence of continuous bubbles indicated a successful intubation. Then, the feeding was to be conducted three times per day with 50 ml per minute and 400-600ml for each feeding.
Study NCT05451732 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nanofat grafting
Description: Naofat grafting in the urethral stricture. The autologous adipose tissue is transferred by injection and in this way, the access to the urethral stricture is carried out with a minimal incision of the male urethra while in the female urethra is transferred exclusively with injections, without incision of urethral tissue.
Study NCT06300788 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.
Study NCT06300788 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PPI and T50 dosing
Description: Sampling for PPI determination and T50 in blood and urine.
Study NCT05932082 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: myomectomy or not
Description: The study group receive myomectomy, while the control group don't receive myomectomy.
Study NCT05932082 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: myomectomy or not
Description: The study group receive myomectomy, while the control group don't receive myomectomy.
Study NCT05111873 — intervention group
Intervention type: OTHER
Intervention: multimodal treatment
Description: combination of medical consultations, psychological therapy, physiotherapy, occupational therapy, disease specific education und progressive muscle relaxation
Study NCT03943901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab is a monoclonal antibody
Study NCT03943901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Chemotherapy drug, alkylating agent
Study NCT03943901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Chemotherapy drug, anthracycline antibiotic
Study NCT03943901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Chemotherapy drug, plant alkaloid
Study NCT03943901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Steroid, anti-inflammatory
Study NCT03943901 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pegfilgrastim
Description: Granulocyte stimulating factor, biologic response modifier
Study NCT06497309 — intervention group
Intervention type: DEVICE
Intervention: Treadmill training
Description: Therapy with treadmill-based advanced technology device.
Study NCT06497309 — intervention group
Intervention type: DEVICE
Intervention: Overground training
Description: Therapy using an advanced technological device enables exercise on the ground.
Study NCT06497309 — intervention group
Intervention type: DEVICE
Intervention: DIERS
Description: The examination starts and ends with the DIERS motion analysis system, a light-optical scanning method based on VRS (Video Raster Stereography) and a sensor-equipped treadmill that allows the measurement of several parameters of gait and balancing ability.
Study NCT06497309 — intervention group
Intervention type: OTHER
Intervention: Traditional physiotherapy assessments
Description: Traditional physiotherapy assessment methods (Timed Up and Go, Berg Balance Test, 6-minute gait test, 10-metre gait test, Functional Independence Measure, Barthel) are used to assess gait pattern and self-sufficiency.
Study NCT06535542 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Whole Genome Sequencing
Description: Participants in this arm will have their blood sample analyzed by whole-genome sequencing (WGS) and will be given access to Predictiv™ Deoxyribonucleic acid (DNA)-based digital twin platform, a web-based interactive application with WGS results. The platform will include positive monogenic and polygenic Familial Hypercholesterolemia results and pharmacogenomics results on statins and clopidogrel. A report of positive monogenic variants will be included in their medical record. This may also include genes on the American College of Medical Genetics and Genomics (ACMG) secondary findings (SF) version 3.2 list if the participant consents to receive these incidental findings. The report will only include pathogenic, likely pathogenic, and variant of uncertain significance (VUS) results.
Study NCT05662150 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low frequency repetitive stimulation
Description: Neuromuscular transmission was tested by using short-lasting low frequency RNS (10 stimuli at 3 Hz). The test was applied on the abductor digiti minimi (ADM), anterior tibial, orbiculis oculi, trapezius, anconeus and EDB muscles of one side, in this particular order, by supramaximal stimulation of the corresponding nerve.
Study NCT04525651 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital Acupuncture Manipulation Therapeutic Instrument
Description: The device is based on the characteristics of traditional acupuncture manipulation of Shanghai School of Traditional Chinese Medicine, and absorbs the information of the techniques of famous experts, modulates the stimulation waveform of the electroacupuncture device by modulating the signal, and realizes the digitization of acupuncture technique information.
Study NCT04525651 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Acupuncture
Description: Manual acupuncture to acheive de qi.
Study NCT04525651 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Acupuncture
Description: Sham acupuncture to avoid de qi.
Study NCT04877496 — intervention group
Intervention type: DRUG
Intervention: History of exposure to anti-CD20 treatment since 01/01/2010
Description: Intravenous treatment history of anti-CD20 treatment since 01/01/2010
Study NCT04877496 — intervention group
Intervention type: BIOLOGICAL
Intervention: Completion of COVID19 vaccine at least 4 weeks ago
Description: Completion of COVID19 vaccination course at least 4 weeks ago.
Study NCT04660760 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Given IV
Study NCT04660760 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Complete questionnaires
Study NCT04660760 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Complete questionnaires
Study NCT04660760 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ramucirumab
Description: Given IV
Study NCT04660760 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Ramucirumab
Description: Given IV
Study NCT04660760 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trifluridine and Tipiracil Hydrochloride
Description: Given PO
Study NCT04960670 — intervention group
Intervention type: OTHER
Intervention: Evaluation of microbiome and maternal/infant lifestyle
Description: Identification of the longitudinal interplay between the intestinal microbiome and infant/maternal nutritional and lifestyle habits, environmental factors exposure and anthropometric measurements, in children with adiposity rebound vs children with early adiposity rebound.
Study NCT06193707 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the Remote Intervention
Description: Remote health intervention refers to the use of big data, artificial intelligence and 5G technology to provide healthcare services and interventions to individuals at a distance. This approach allows healthcare providers to deliver medical care, monitor patients' health, offer consultations, provide education, and offer support without the need for in-person interaction.
Study NCT06193707 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: the Traditional Intervention
Description: Ultrasound follow-up review is recommended. If there is suspicious change in the lesion during follow-up, biopsy should be considered to clarify the nature of the pathology.
Study NCT05905562 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stabilization exercises
Description: Core muscles activation exercises will be performed on patients to target the abdominals.
Study NCT05905562 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal mobilization techniques
Description: lumbar spine joint mobilization techniques will be performed to patient in prone lying.
Study NCT05905562 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal mobilization techniques
Description: lumbar spine joint mobilization techniques will be performed to patient in prone lying.
Study NCT04804527 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intensified physiotherapy
Description: Physiotherapy x2
Study NCT04804527 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care physiotherapy
Description: Physiotherapy x1
Study NCT05378113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ondansetron
Description: Ondansetron (Zofran) is a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist commonly used to treat postoperative nausea and vomiting.
Study NCT05378113 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine
Description: Lidocaine is a local anesthetic agent used intravenously prior to the propofol injection. Currently the standard of care to help decrease the severity of pain in the injection site, a common side effect of propofol.
Study NCT04715126 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oxyjun
Description: One capsule to be taken after breakfast with water.
Study NCT04715126 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One capsule to be taken after breakfast with water.
Study NCT06181747 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a serious mobile device-based game prototype (Save the Muse Home)
Description: The cognitive impairment corresponding to the symptoms, which we are interested in, focuses on executive inhibition, motor inhibition, sustained attention, selective attention, working memory, and planning ability. The training content will be presented in different scenarios as effective training components. The story line of the warrior breakthrough runs through the whole game, each level is adapted according to the functional damage areas of different patients, and each level involves reward and punishment mechanisms to keep the interest of the players, the difficulty gradient of each level is kept moderate, and the game includes design elements such as space, time, object attributes, actions, rules, skills, and probabilities, etc., which ultimately completes Save the Muse Home, a serious game for the treatment of ADHD.
Study NCT06303947 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric tube
Description: The group is given enteral nutritional support with Nasogastric tube according to the relevant guidelines. Within 4 hours after admission, the placement of the feeding tube was conducted by professional medical staffs and after intubation, the tube was secured to the patient's cheek with medical tape. The feeding was conducted once every 3-4 hours, with 200-300ml each time. The total feeding volume was determined based on daily requirements. The feeding content was formulated by the nutritionists based on the patient's condition and relevant guidelines to reach the energy demand as 20-25 kcal/kg/day and protein supplementation of 1.2-2.0 g/kg/day for both two groups. For patients with limited tube feeding compliance, we made appropriate adjustments to ensure that they were not at risk of severe malnutrition as much as possible.
Study NCT06303947 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.
Study NCT06303947 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Comprehensive rehabilitation training
Description: Basic treatment, including corresponding control of risk factors and education on healthy lifestyles.~Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.~Pulmonary function training, including standing training, cough training, and diaphragm muscle training.
Study NCT06237387 — intervention group
Intervention type: OTHER
Intervention: Periodontal examination
Description: Determining the patient's oral hygiene status and the severity of gingivitis. For this purpose, the non-invasive Löe-Silness plaque and gingival index system will be used.
Study NCT06056349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam oral solution
Description: Buccal administration
Study NCT06056349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ClonazePAM Oral Product
Description: Orodispersable
Study NCT06056349 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual medication/ traditional
Description: Medication that is usually used in the emergency department
Study NCT04668001 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Near-Infrared Transcranial Photobiomodulation
Description: tPBM-NIR involves the use of a device that administers near-infrared light over the scalp. The light activates target brain regions.
Study NCT04668001 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Transcranial Photobiomodulation
Description: tPBM-Sham involves the use of an identical device to tPBM-NIR but does not administer near-infrared light. It mimics the sensation by applying heat but does not actually activate target regions of the brain
Study NCT05271006 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The mHealth platform to be used by the exercise group is Down Dog, which has a suite of apps for yoga, HIIT, barre, and running workouts. Down Dog has agreed to provide free memberships for one year to all participants in the study. To ensure participant de-identification on the Down Dog platform, each participant will receive a Participant ID which will be pre-registered by the study coordinator on the Down Dog platform. Randomized participants will be provided instructions for downloading the apps onto their phone or a link to the website to be used on their computer. Following randomization, participants in the exercise group will be asked to engage in physical activity (using any if the Down Dog apps), 4 days a week for 20 minutes a day for 12 weeks.
Study NCT06154603 — intervention group
Intervention type: PROCEDURE
Intervention: Surgical treatment type
Description: This observational design will study the clinical outcome for each type of upper gastrointestinal perforation in relation to surgical or non-surgery treatment and in relation to treatment centre.
Study NCT05452031 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care2Sleep
Description: A multicomponent behavioral sleep program, consisting of sleep hygiene, stimulus control, sleep compression, pleasurable activity, daily walking, and light exposure.
Study NCT05452031 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care2Sleep
Description: A multicomponent behavioral sleep program, consisting of sleep hygiene, stimulus control, sleep compression, pleasurable activity, daily walking, and light exposure.
Study NCT05452031 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Sleep Education
Description: This group will receive information about sleep, aging, and dementia, but without specific or individualized recommendations
Study NCT05620771 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab and Bevacizumab
Description: Patients will receive atezolizumab + Bevacizumab for 21 days after standard of care therapy is complete.
Study NCT05620771 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Y90 + TKI
Description: Patients will receive TKI for 21 days after standard of care therapy is complete.
Study NCT04914078 — intervention group
Intervention type: DRUG
Intervention: Mepolizumab 100 MG
Description: The patients will treated with subcutaneous Mepolizumab at 100 mg every 30 days. Patients will be recruited among those eligible to Mepolizumab treatment according to the Italian Medicine Agency (AIFA; Agenzia Italiana del Farmaco) guidelines who will accept to participate to the study. In particular inclusion criteria will be: severe (Step 4 and 5 GINA) asthma with at least blood eosinophilic count above 300 cells/mcl at least once in the previous year and ≥150 cells/mcl in the absence of systemic corticosteroid treatment before biological treatment initiation. In addition, one of the following conditions will be required: 1) ≥2 exacerbations in the previous year despite appropriate inhaled treatments or 2) the need for systemic corticosteroids on top of inhaled treatment for at least 6 months in the previous year.
Study NCT05071560 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Combined exercise training
Description: Before the intervention, these women will undergo an evaluation of cardiorespiratory fitness, functional fitness, psychological status and a physiatry assessment. A consent form is signed before the start.~The physical exercise intervention was planned based on the recommendations of the American College of Sports Medicine for cancer survivors (ACSM 2019), with two supervised combined training sessions (mobility, aerobic training, strength and flexibility training) planned, and one unsupervised aerobic training session per week, interspersed with at least one rest day in between, for 8 weeks. The intensity will be individualized and defined based on the initial assessment. The structure of the training plan was based on the FITT-VP principles (frequency, intensity, time, type, volume and progression) recommended by the ACSM (2019).
Study NCT05071560 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined exercise training
Description: Before the intervention, these women will undergo an evaluation of cardiorespiratory fitness, functional fitness, psychological status and a physiatry assessment. A consent form is signed before the start.~The physical exercise intervention was planned based on the recommendations of the American College of Sports Medicine for cancer survivors (ACSM 2019), with two supervised combined training sessions (mobility, aerobic training, strength and flexibility training) planned, and one unsupervised aerobic training session per week, interspersed with at least one rest day in between, for 8 weeks. The intensity will be individualized and defined based on the initial assessment. The structure of the training plan was based on the FITT-VP principles (frequency, intensity, time, type, volume and progression) recommended by the ACSM (2019).
Study NCT05539105 — intervention group
Intervention type: PROCEDURE
Intervention: Double tract reconstruction
Description: Double tract reconstruction would be applied after radical proximal gastrectomy.
Study NCT05539105 — intervention group
Intervention type: PROCEDURE
Intervention: Gastric conduit reconstruction
Description: Gastric conduit reconstructionn would be applied after radical proximal gastrectomy.
Study NCT05539105 — intervention group
Intervention type: PROCEDURE
Intervention: Other reconstructions
Description: Other reconstructions except for double tract and gastric conduit reconstructions would be applied after radical proximal gastrectomy.
Study NCT05606224 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: internet-based mindfulness intervention for emotional distress
Description: The internet-based self-help version of the Mindfulness Intervention for Emotional Distress (iMIED) program integrates rationales and practices from the UP and MBIs. Formal mindfulness exercises (e.g., body scan, mindful breathing, and mindful stretching) and informal mindfulness practices (e.g., mindful tooth-brushing) were retrieved from MBIs. In addition, iMIED selected several important tasks from the UP, like practicing tolerating uncomfortable feelings by interoceptive exposure practices (e.g., rapid breathing), identifying avoidant behaviors and emotion-driven behaviors and reducing them step by step, identifying common maladaptive automatic thoughts (e.g., overestimating probability and catastrophizing), and using the above strategies in daily life by completing challenging tasks.
Study NCT05006521 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KN-002
Description: KN-002 dry powder inhaler
Study NCT04457453 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Macintosh in sniffing position
Description: Macintosh direct intubation in sniffing position
Study NCT04457453 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Macintosh in Trendelenburg position and Sellick position
Description: Macintosh direct laryngoscopic intubation in Trendelenburg position and Sellick position
Study NCT04457453 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AceScope in Trendelenburg position and Sellick position
Description: AceScope videolaryngoscopic intubation in Trendelenburg position and Sellick position