AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06708962 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: corticosteroid injection for rotator cuff tendinopathy
Description: corticosteroid injection for rotator cuff helps resolving inflammation which occur for paraplegic patients from overuse of the crutches
Study NCT06713486 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fixed pressure obtained in the polysomnography for 28 days
Description: home nocturnal therapy either at the fixed pressure obtained in the polysomnography for 28 days
Study NCT06713486 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dynamic pressure in Dreamstation AVAPS-AAM PhilipsRespironic® mode
Description: dynamic pressure in Dreamstation AVAPS-AAM PhilipsRespironic® mode (program B) for 28 days, using the apnea threshold obtained in the titration as the maximum EPAP pressure and adjusting the support pressure for inferred Vt to 8 ml/kg of ideal body weight. After the first 28 days, a polysomnography will be performed under therapy with the device, and the next morning, cycle ergometry will be conducted.
Study NCT06713421 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimethicone+Pronase
Description: Approximately 15-20 minutes before EGD, patients orally receive 50mL of warm water containing 5g dimethicone powder and 20,000 IU pronase granules combined with 1 g NaHCO3.
Study NCT06713421 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dimethicone
Description: Approximately 15-20 minutes before EGD, patients orally receive 50mL of warm water containing 5g dimethicone powder.
Study NCT06713421 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: with Postural Exercise
Description: After the premedication is administered orally approximately 15-20 minutes before EGD, patients are asked to take a 3-minute postural exercise.
Study NCT06713421 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: with Postural Exercise
Description: After the premedication is administered orally approximately 15-20 minutes before EGD, patients are asked to take a 3-minute postural exercise.
Study NCT06713421 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: without Postural Exercise.
Description: After the premedication is administered orally approximately 15-20 minutes before EGD, patients sit quietly awaiting examination.
Study NCT06713421 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: without Postural Exercise.
Description: After the premedication is administered orally approximately 15-20 minutes before EGD, patients sit quietly awaiting examination.
Study NCT06711549 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Serratus Posterior Superior Plane Intercostal Plane block
Description: Under ultrasound guidance; local anesthetic will be injected in the plane between the posterior aspect of the serratus posterior superior plane and the ribs
Study NCT06711549 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Serratus Anterior Plane block
Description: Under ultrasound guidance; local anesthetic will be injected in the plane between the posterior aspect of the serratus anterior and the external intercostal muscles and ribs
Study NCT05967403 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Propofol administration rate will be controlled by a feedback loop facilitated by BIS monitoring using the conventional closed loop anaesthesia delivery system (CLADS). A BIS value of 50 will be used as the target point for induction and maintenance of anaesthesia.
Study NCT05967403 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Propofol administration rate will be controlled by a feedback loop facilitated by BIS monitoring using the hermetic closed loop anaesthesia delivery system (CLADS). A BIS value of 50 will be used as the target point for induction and maintenance of anaesthesia.
Study NCT04423588 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: dexlansoprazole serum concentration
Description: 6 blood samples are collected at fixed time Points after oral Administration of 1 dose of dexilant at regular patients visits preoperatively and 3 and 6 months post-surgery.
Study NCT06119399 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional exercise program for chronic neck pain
Description: Patients will perform three repetitions of stretching exercises for neck flexor, extensor, lateral flexor, and rotator for 30 seconds as warm-up and cool-down exercises, to relieve tension on each side of the neck.~Then cranio-cervical flexion exercise will be started using feedback from an air-filled pressure sensor placed behind the neck. Subjects will lay in the crook lying position. The pressure biofeedback unit will be placed below the occiput and inflated up to a baseline pressure of 20 mmHg. The subjects will be instructed to perform head-nodding action to progressively target 5 pressure levels (hold 10 seconds with brief rest periods between each contraction 3-5 seconds). This includes 3 sets in a session for 10 repetitions each with 2 minutes of rest between sets and 3days a week for 6 weeks.
Study NCT04423588 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: upper endoscopy
Description: 6 and 12 months after surgery the occurrence of marginal ulcers in the same Patient Group is examined by upper endoscopy. The 12-month endoscopy is part of the Routine postoperative diagnosis, the 6-month endoscopy is for study purpose.
Study NCT04857944 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IDEA program (Improving depressive symptoms through personalised exercise and activation)
Description: The program will consist of six 90-minute group sessions composed of four to six participants. These short intervention sessions will be distributed in one month, with a frequency of once or twice a week depending on the week of the program. Of the six sessions, two will be exercise-oriented and will include on-site practice. The remaining four sessions will include definitions of depressive symptomatology, the relationship between depression and having an active lifestyle, motivation and barriers towards exercise, and maintenance strategies.
Study NCT04857944 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: IDEApp
Description: An ad-hoc app (IDEApp) combined with a fitness tracker to register and store participants' physical activity, exercise compliance, and sleep patterns. The app will deliver motivational or awareness messages when the fitness tracker detects non-compliance with the exercise prescription, physical activity decreases, or altered sleep patterns.
Study NCT04857944 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IDEApp
Description: An ad-hoc app (IDEApp) combined with a fitness tracker to register and store participants' physical activity, exercise compliance, and sleep patterns. The app will deliver motivational or awareness messages when the fitness tracker detects non-compliance with the exercise prescription, physical activity decreases, or altered sleep patterns.
Study NCT06220045 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Polyvinylidene fluoride mesh
Description: Midline laparotomy closure using the small bites technique associated with a prophylactic suprafascial polyvinylidene fluoride mesh.
Study NCT06220045 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Prophylactic polypropylene mesh
Description: Midline laparotomy closure using the small bites technique associated with a prophylactic suprafascial polypropylene mesh.
Study NCT04893421 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MOLLI Localization
Description: Patients will be implanted with a MOLLI seed using a specialized introducer needle under imaging guidance. A special handhold probe and detection system will be used intraoperatively to assist in excision.
Study NCT04956354 — intervention group
Intervention type: DEVICE
Intervention: ANNE™ Monitoring System (2 sensors) - version B
Description: ANNE™ is a wireless vital sign monitoring device that uses soft, flexible, skin-mountable biosensors (ANNE™ Chest and ANNE™ Limb) with Bluetooth® 5 enabled and encrypted data communication to an iPad application. Study sensors to be applied on patients are:~Sensor 1 - A chest unit (ANNE™ Chest) with embedded battery, sensors, and a three-axis accelerometer that captures the following signals: electrocardiography (ECG), temperature, seismocardiography (SCG) and the chest wall movements.~Sensor 2 - A limb unit (ANNE™ Limb) with embedded battery that captures the photoplethysmography (PPG) and SpO2 signals.
Study NCT04354103 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atomoxetine
Description: Atomoxetine
Study NCT04956354 — intervention group
Intervention type: DEVICE
Intervention: ANNE™ Monitoring System (2 sensors) - version C
Description: ANNE™ is a wireless vital sign monitoring device that uses soft, flexible, skin-mountable biosensors (ANNE™ Arc and ANNE™ Limb) with Bluetooth® 5 enabled and encrypted data communication to an iPad application. Study sensors to be applied on patients are:~Sensor 1 - ANNE™ Arc with a Lithium-Polymer battery that contains a 6-axial inertial measurement unit (IMU), which includes a 3-axis gyroscope and 3-axis accelerometer, a power management component, an analog front-end component, passive electrodes for ECG, and bio-impedance feature that capture the following waveforms: heart rate (HR), respiratory rate (RR) and skin temperature.~Sensor 2 - A limb unit (ANNE™ Limb) with embedded battery that captures the photoplethysmography (PPG) and SpO2 signals.
Study NCT06224270 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Adjuvanted Recombinant Zoster Vaccine (RZV)
Description: The RZV vaccine is indicated for prevention of herpes zoster (HZ) in adults aged 18 years and older who are or will be at increased risk of HZ. Patients with IBD on immunosuppressive therapy are at increased risk for HZ.
Study NCT05484024 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: PD-1 inhibitor
Study NCT05484024 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Short-course radiotherapy
Description: Pelvic radiation
Study NCT05484024 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Short-course radiotherapy
Description: Pelvic radiation
Study NCT05484024 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: CAPOX/mFOLFOX
Description: chemotherapy regimen
Study NCT05484024 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CAPOX/mFOLFOX
Description: chemotherapy regimen
Study NCT06231628 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous cementoplasty
Description: Percutaneous image guided cementoplasty will be performed as follows:~Low-viscosity radiopaque bone cement will be quickly mixed and transferred to 1-ml syringes to reduce injection resistance. Injection will be initiated 2-4 min after mixing. When the resistance to cement injection becomes high in the beginning, the cement will be pushed in with a stylet, and it will go well afterward. As much bone cement as possible will be injected while avoiding leakage into the hip joint, sciatic notch, or veins under fluoroscopic monitoring. When significant cement leakage occurred at the initial stage, cement injection will be performed via another route or will be stopped and resumed when the cement viscosity increased. The cement will begin to harden after 8 min, and the operator, therefore, will aim to complete the delivery of the injection within 10 min. The injection needles must be removed before the cement hardens completely
Study NCT05526911 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TBAJ-876
Description: * Day 6 to Day 13: 200 mg TBAJ-876 oral suspension, fed~* Day 14 to Day 19: 165 mg TBAJ-876 oral suspension, fed~* Day 20 and Day 21: 200 mg TBAJ-876 oral suspension, fasting~* Day 22 to Day 24: 150 mg TBAJ-876 oral suspension, fed
Study NCT05526911 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Day 1 and Day 20: Midazolam oral syrup: 2 mg, fasted
Study NCT05526911 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Digoxin
Description: Day 2 and Day 21: Digoxin tablet: 0.25 mg, fasted
Study NCT05916885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: short-intensity modified CIMT and conventional therapy
Description: an experimental group receiving short-intensity modified CIMT and conventional therapy
Study NCT04742894 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Visual Feedback Training
Description: Participants will be trained to work with a computer setup to control the position of a visual cursor on the screen using their speech while their auditory feedback is altered. The goal of the training is to help improve speech production and motor control ability.
Study NCT05916885 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy alone
Description: a control group receiving conventional therapy alone.
Study NCT04680897 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Early restriction release
Description: Participants will no longer have restrictions on vaginal penetration 2 weeks after surgery.
Study NCT04680897 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Standard restriction recommendation
Description: Participants will return to intercourse after 6 weeks
Study NCT05507697 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HUC-MSCs
Description: 5 × 10\^6 cells/mL, 1 mL per injection, each injection point is 2 cm apart ,1.0-1.5 cm deep, total amount of injection is estimated based on the surface area of the patient's lower limb
Study NCT05507697 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Lipoic Acid
Description: Lipoic Acid Injection，600 mg/d for 15 consecutive days
Study NCT05080595 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transportation assistance (Lyft rides)
Description: Lyft rides will be provided to patients for any transplant-related medical visits
Study NCT05448261 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion-centered problem-solving intervention (EPi)
Description: The EPi is built upon the model of relational/problem-solving model of stress and is aimed at supporting caregivers in (1) revisiting stressful caregiving and associated problem from a psychological distanced perspective; (2) adopting problem orientation toward one's experience in the present moments with curiosity, openness and acceptance; and (3) applying the problem-solving skills learned for the enhancement of their psychosocial wellbeing in the stressful caregiving context. To reduce the incongruence between caregivers and stroke survivors in problem-solving, we will adopt a shared problem, shared action plan approach for the family caregivers and stroke survivors.
Study NCT05448261 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: stroke education
Description: Information is related to stroke and recurrent stroke and strategies for assisting stroke survivors in day-to-day activities.
Study NCT05898763 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TEIPP24 (LRPAP7-30V-SLP vaccine in Montanide ISA-51)
Description: Patients will receive three rounds of vaccination three weeks apart via one subcutaneous (SC) injection in an alternating limb. Patients in the extension cohort will receive the highest safest dose in combination with pembrolizumab (a CPI).These patients will receive three rounds of combination treatment with TEIPP24 vaccination and pembrolizumab every three weeks. Pembrolizumab will be administered as per standard of care.
Study NCT05425745 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obicetrapib
Description: 10 mg Obicetrapib tablet
Study NCT05425745 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo tablet made to resemble active
Study NCT05093140 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: Induction therapy:~Camrelizumab 200mg, ivd, D1, Rituximab 375mg/m2, ivd, D1 every 3 weeks up to 2 cycles~Immunochemotherapy:~Rituximab: 375mg/m2, ivd, D1; Cyclophosphamide: 750mg/m2, iv or ivd, D1; Hydroxyldaunorubicin: 50mg/m2, iv or ivd, D1; Vincristine: 1.4 mg/m2 , iv(max：2mg), D1; Prednisone: 60mg/m2, po, d1-5 every 3 weeks up to 6 cycles Maintenance therapy: Camrelizumab 200mg, ivd, D1 every 4 weeks up to 6 cycles
Study NCT05143281 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone 0.4 MG [Dextenza]
Description: Ophthalmic Intracanalicular Insert
Study NCT05269433 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OCAT-sham
Description: Placebo version of the online contingent attention training preceded by a psycho-education movieclip.
Study NCT05269433 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OCAT
Description: Online contingent attention training preceded by a psycho-education movieclip.
Study NCT05269433 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psycho-education video
Description: All groups watch a psycho-education video before the start of the 10-day attention training.
Study NCT05269433 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Psycho-education video
Description: All groups watch a psycho-education video before the start of the 10-day attention training.
Study NCT05269433 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motivational video
Description: Participants in the OCAT+ condition watch a short motivational video before each training session.
Study NCT05616975 — intervention group
Intervention type: OTHER
Intervention: test-retest reliability
Description: Assessing the test-retest reliability of SWAY Balance, Functional, and Cognitive tests.
Study NCT05616975 — intervention group
Intervention type: OTHER
Intervention: construct validity
Description: Investigating the construct validity of SWAY Balance, Functional, and Cognitive tests.
Study NCT05616975 — intervention group
Intervention type: OTHER
Intervention: normative data
Description: Collection of normative SWAY Balance, Functional, and Cognitive data.
Study NCT05352711 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active assisted exercise and with fully immersive Head-Mounted Display virtual reality ( Oculus Quest virtual reality (VR) headset with hand con
Description: VR is mainly created by generating visual effects through head-mounted display (HMD) systems. An HMD is a device worn on the head or as part of a helmet with a built-in display and lenses, allowing the user to experience the virtual world with the help of a wide viewing angle, head and hand movements tracking as well as objects interacting by controllers.
Study NCT05352711 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: active assisted range of motion exercise
Description: Patients were treated active assisted ROM physical therapy 2 sessions per week for 4 weeks.
Study NCT05578170 — intervention group
Intervention type: DRUG
Intervention: Pembrolizumab
Description: Participants receive 200 mg pembrolizumab as a neoadjuvant by intravenous (IV) infusion administered on Day 1 of a 21-day cycle for 2 cycles before surgery.
Study NCT04239053 — intervention group
Intervention type: DRUG
Intervention: Bupivacaine
Description: Measuring the plasma concentration level of bupivacaine after applying ESPB
Study NCT06550193 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided procedure using AR/VR technology
Description: Participants will receive the intervention, which involves utilizing AR/VR technology during ultrasound-guided procedures (e.g., regional anesthesia, line placement). All participants will receive standard pre- and post-block or line care as they normally would for the ultrasound-guided procedure.
Study NCT06232226 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Patients suffering from the co-occurrence of ADHD and addiction(s)
Description: All eligible patients over 15 years and 3 months (age limit between child psychiatry and adult psychiatry), presenting both a diagnosis of ADHD and a diagnosis of at least one addictive disorder (SUD, AUD (Alcohol Use Disorder) and/ or behavioral addiction), starting care in one of the three participating centers, and meeting the indication for treatment with MPH according to European recommendations (J. J. S. Kooij et al., 2019)
Study NCT06219785 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Low-Intensity Shockwave therapy (LiSWT)
Description: Participants will receive once-a-week LiSWT treatments of 0.2 mJ/ mm² over the lateral penile shaft (distal, mid, and proximal penile shaft), 500 impulses in each area, for a total of 1500 shocks along the penis once a week for six weeks, with a total of 6 treatments once a week.
Study NCT06219785 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Low-Intensity Shockwave therapy (LiSWT)
Description: Participants will receive once-a-week LiSWT treatments of 0.2 mJ/ mm² over the lateral penile shaft (distal, mid, and proximal penile shaft), 500 impulses in each area, for a total of 1500 shocks along the penis once a week for six weeks, with a total of 6 treatments once a week.
Study NCT05356403 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Difelikefalin 1 mg Oral Tablet
Description: Difelikefalin 1 mg medication taken orally 1 time/day
Study NCT05356403 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Placebo tablet taken orally 1 time/day
Study NCT05612243 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Consumption of a meal with yogurt enriched with probiotics immobilized on oat flakes and polyphenols
Description: Participants will consume a meal including 200g of yogurt enriched with Lacticaseibacillus rhamnosus probiotics (3\*10\^9 cfu/g) immobilized on oat flakes (1g) and polyphenol-rich lyophilized extract (250mg) of Cistus Albidus (77,3 mg GAE/g), as well as two slices of white bread (80g) with butter (30g). Then blood biomarkers will be examined to determine the effect of functional yogurt on postprandial glycemia and lipemia