AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05666167 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group Telehealth Exercise Sessions with text messaging plus booster sessions
Description: Participants receive 3 months of group telehealth exercise initiation plus text messaging followed by 6 months of text messaging plus monthly group telehealth exercise booster sessions.
Study NCT06514768 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: JY231
Description: Infusion of JY231 Injection by dose of 1-10×10\^6 Transduction Units(TU)/ kg、1-5×10\^7 TU/kg、5-10 ×10\^7 TU/kg. Administration method: intravenous infusion、Splenic artery infusion、Lymph node infusion; Subjects will be treated with Fludarabine and Cyclophosphamide before cell infusion (PI evaluation is required)
Study NCT05945537 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INI-822 (A)
Description: Different dose levels of INI-822
Study NCT05945537 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (B)
Description: Matching placebo to INI-822
Study NCT05452343 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CM310
Description: 600 mg (first doing) + 300 mg (subsequent dosing), once every two weeks
Study NCT05452343 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: CM310
Description: 600 mg (first doing) + 300 mg (subsequent dosing), once every two weeks
Study NCT06518746 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cryopreservation of gonadal tissue
Description: Patients at risk for primary gonadal tumors will undergo unilateral or bilateral gonadectomy for clinical purposes as a standard of care, and a portion of the surgically removed tissue will be cryopreserved for fertility preservation. The pathologist will assess the tissue using sterile technique and every other section will undergo histologic analysis, including evaluation for the presence of tumor or viable germ cell elements. The sections of the tissue for fertility preservation will be refrigerated and held until a final diagnosis is made on the tissue sections that are being processed for histologic analysis. If no tumor is identified and viable germ cell elements are identified, the tissue sections allotted for preservation will be sent in holding media for processing and cryopreservation.
Study NCT05406635 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Biomarkers: Troponins and natriuretic peptides
Description: Biomarker monitored treatment with measurement of NT-proBNP and cTNT / TNI in weeks 0, 9, 18, 30 and 48 of the treatment period.
Study NCT06297811 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trilaciclib Injection
Description: Experimental: trilaciclib group Intervention: Drug: Trilaciclib Injection \[Cosela\] 240 mg/m\^2, intravenous drip over 30 min within 4 hours before chemotherapy administration on the same day
Study NCT06297811 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Drug: Paclitaxel 175 mg/m\^2, intravenous drip over ≥ 3 hours , d1, Q3W, at least 6 cycles.
Study NCT06297811 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Drug: Paclitaxel 175 mg/m\^2, intravenous drip over ≥ 3 hours , d1, Q3W, at least 6 cycles.
Study NCT06297811 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: area under curve(AUC) 5\~6, intravenous drip over ≥ 1 hours, d1, Q3W, at least 6 cycles.
Study NCT06297811 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: area under curve(AUC) 5\~6, intravenous drip over ≥ 1 hours, d1, Q3W, at least 6 cycles.
Study NCT05865119 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OPTIMUS covered stent
Description: The procedure involves placement of a long and large balloon-expandable covered stent in the superior vena cava that tunnels the abnormal pulmonary venous return to the left atrium.
Study NCT05865119 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical correction of a SVD
Description: Under cardiopulmonary bypass and open heart surgery, surgical correction of SVD either using single patch, double patch or Warden techniques
Study NCT05653076 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hibiscus sabdariffa extract
Description: Daily supplementation with 520 mg of Hibiscus sabdariffa extract for 10 days.
Study NCT05653076 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Hibiscus sabdariffa extract
Description: Daily supplementation with 520 mg of Hibiscus sabdariffa extract for 10 days.
Study NCT06383728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: Patients with resectable stage II-IIIB EGFR-mutated lung squamous cell carcinoma will receive Osimertinib ( 80mg/d, ≥9 weeks).
Study NCT06230237 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Smiling is fun + professional support
Description: Participants will receive an intervention called Smiling is Fun; a cognitve-conductual online program with the most effective psychological procedures for depression and other techniques to promote coping ability, emotional regulation and resilience along 8 modules.~While they do the online program, they will receive periodically professional support. The professional support will be contacts of 20 minutes long, will take place every two weeks and will last 3 months.
Study NCT06230237 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Smiling is fun
Description: Participants will receive an intervention called Smiling is Fun; a cognitve-conductual online program with the most effective psychological procedures for depression and other techniques to promote coping ability, emotional regulation and resilience along 8 modules.
Study NCT05039983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EGCG
Description: EGCG use various concentrations dissolved in 0.9% saline solution three times a day. A new batch is made up each time. For esophageal application, repeated swallowing of 30 ml of the EGCG solution is indispensable to assure the prolonged presence of drug the esophageal walls.
Study NCT05427188 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stress paradigm
Description: HV will receive mental arithmetic challenges, together with social evaluative threat components from the program and/or the investigator
Study NCT05427188 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham paradigm
Description: HV will receive mental arithmetic challenges where threat components from the program and/or the investigator are absent
Study NCT06344221 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dextrain Manipulandum and haptic feedback device
Description: Assessment of key components of manual dexterity in addition to vibrotactile stimulation on the fingers and wrist.
Study NCT06344221 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dextrain Manipulandum and haptic feedback device
Description: Assessment of key components of manual dexterity in addition to vibrotactile stimulation on the fingers and wrist.
Study NCT06127849 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Resistance Training + Placebo (Capsule) + Placebo (Sachet)
Description: * Placebo sachet of 20 gms dissolved in 200-300 ml water. One sachet to be taken in the Morning and one in the evening.~* One Placebo capsule to be taken 30 minutes after sachet in the morning.
Study NCT06127849 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Training + Whey protein (40 gms) + Placebo (Capsule)
Description: A sachet of 20 gms of Whey protein isolate (WPI) dissolved in 200-300 ml water. One sachet to be taken in the Morning and one in the evening.~- One Placebo capsule to be taken 30 minutes after whey protein in the morning
Study NCT06127849 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Training + Whey protein (40 gms) + EB-PA (500 mg)
Description: * A sachet of 20 gms of Whey protein isolate (WPI) dissolved in 200-300 ml water. One sachet to be taken in the Morning and one in the evening.~* One capsule of EB-PA to be taken 30 minutes after whey protein in the morning
Study NCT05682196 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab added to standard of care treatment
Description: Rituximab with standard of care treatment
Study NCT05682196 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard of care treatment alone
Description: Standard of care treatment alone
Study NCT06371781 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Serum Netrin-4, Resistin and Sfrp-5 level measurement
Description: Measurements of the levels of these molecules in the serum samples of the study group will be done with the ELISA kit.
Study NCT05324514 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Split-thickness skin grafting
Description: Harvesting for split-thickness skin grafting will be performed at the specified donor site using a pneumatically powered dermatome with a setting of 10 /1000th inch and meshed 2:1.
Study NCT05324514 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High density microscopic skin tissue column grafting
Description: MSTC harvest will be conducted using the ART system (Medline Industries) in accordance with the manufacturer's instructions and distributed at high density (300-360 columns/50cm2).
Study NCT05324514 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low density microscopic skin tissue column grafting
Description: MSTC harvest will be conducted using the ART system (Medline Industries) in accordance with the manufacturer's instructions and distributed at low density (150-180 columns/50cm2).
Study NCT06161389 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Partially inflated mask
Description: Manikin ventilation with a partially inflated mask
Study NCT06161389 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fully inflated mask
Description: Manikin ventilation with a fully inflated mask
Study NCT05585450 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: BL32 and BL33 will be inserted by needles of 0.30×75mm size at an angle of 45°, inward and downward, to the depth of 60-70mm. BL35 will be inserted by needles of 0.30×75mm size, slightly outward and upward, to the depth of 60-70mm. SP6 will be inserted by needles of 0.30×40mm to the depth of 25-30mm. The needles will be lifted, thrust, and twisted evenly three times after insertion to induce the sensation of deqi.~The electronic acupuncture apparatus (Yingdi KWD 808I electro pulse acupuncture therapeutic apparatus, Changzhou Yingdi Electronic Medical Device Co., Ltd) will be connected to the four pairs of needles transversally, with a continuous wave of 5 Hertz (Hz) and an electric current of 2-6.5 milliampere (mA) for BL32, BL33 and BL35, and 0.5 mA-2mA for SP6.
Study NCT05585450 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham electroacupuncture
Description: The four pairs of acupoints will be inserted by needles of 0.30×25mm or 0.30×40mm size to a depth of 2-3mm till the needles can stand still. No manipulations will be conducted, and the sensation of deqi will not be induced.~The electronic acupuncture apparatus (Yingdi KWD 808I electro pulse acupuncture therapeutic apparatus, Changzhou Yingdi Electronic Medical Device Co., Ltd) will be connected to the four pairs of needles transversally, with a continuous wave of 5 Hz and a minimal electric current (ideally at a degree which participant can just percept). In about 30 seconds, the electric current will be turned down, leaving the indicator light and ticking sound on.
Study NCT02217202 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aquacel Ag dressing
Description: Participants will have their knee arthroplasty wound dressed using the Aquacel Ag dressing instead of the standard Aquacel dressing.
Study NCT06165393 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Slow-release CHO-AA
Description: Slow-release CHO-AA, alginate encapsulated
Study NCT06165393 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Slow-release CHO
Description: Slow-release CHO, alginate encapsulated
Study NCT06165393 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CHO
Description: Carbohydrate-only, control
Study NCT05417919 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Solution-oriented Nursing in Violence Against Women (SONVAW)
Description: The Personal Information Form was filled in by the students themselves before the program. İSKEBE was filled before, after the program and at the follow-up 3 months later. 3 days were determined for the program for the students in the experimental group, and the program was applied for 60 minutes a day for 6 weeks, allowing the students to participate in the program on a suitable day
Study NCT05902806 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Upgraded tube feed
Description: Total duration of study: 4 weeks; 1 week on current tube feed followed by 2 weeks on upgraded tube feed comparable in energy density and fiber content as their current tube feed. The tube feeding regimen is similar to pre study feeding regimen. There will then be a one week follow up period.
Study NCT06516016 — intervention group
Intervention type: RADIATION
Intervention: PET
Description: \[18F\]DPA-714 will be injected intravenously as a 1 minute intravenous bolus injection and dynamic PET acquisition will last 90 min. The aim is the quantification of the neuroimmune reaction during neuroinflammation process.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: MRI 3T
Description: Brain MRI will aim at providing imaging biomarkers which will allow evaluating brain structure, microstructure, iron load, myelin, neurodegeneration of the substantia nigra and locus coeruleus, functional connectivity, brain perfusion and the glymphatic system.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: Oculomotricity assessment
Description: Recording eye movements in a controlled environment (requiring no specific room or area) in binocular vision at a frequency > 500Hz, while retaining infrared video footage of eye movements for high-quality clinical monitoring.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: Magnetoencephalography assessment
Description: Recording brain magnetic activity using the Elekta Neuromag® TRIUX Magnetoencephalograph ; The participant will be comfortably seated in an adjustable-height chair. The device is enclosed in a shielded room isolated from external electric and magnetic fields to measure the extremely weak magnetic activities produced by the brain.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: Body posture and gait assessment
Description: The acquisition of kinematic gait parameters will be achieved ; markers are positioned on the different segments of members, recognized by a camera system positioned on the walls. Neurophysiologic muscular activity of the lower limbs will also be recorded.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: Voice recording
Description: Participants will be recorded during a single session at every visit upon baseline with a professional quality head mounted microphone.
Study NCT06516016 — intervention group
Intervention type: OTHER
Intervention: Video-polysomnography
Description: Participants will complete standard sleep questionnaires before the visit and perform neurophysiological tests including cognitive tasks before and after the sleep recording.
Study NCT06516016 — intervention group
Intervention type: BIOLOGICAL
Intervention: Blood sampling, skin biopsy, excreta sampling, lumbar puncture
Description: Experimental analyses, genetic and multi-OMIC analyses for biomarker research.
Study NCT06225713 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: focused power ultrasound mediated inferior perirenal adipose tissue modification
Description: This novel focused power ultrasound is an externally delivered, completely noninvasive focused therapeutic ultrasound device. It is capable of focusing the resulting ultrasound beam to a small cigar-shaped volume and monitoring the temperature of the target area, which leads to the rapid elevation of the peri-renal adipose tissue temperature and the destruction of target tissue eventually.
Study NCT06225713 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham-control group
Description: Participants will receive the sham control therapy (including peri-renal fat ultrasonic measurement and localization, focused ultrasound treatment parameters setting), however, without initiating the focused ultrasound equipment.
Study NCT06193668 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High-fat overnutrition
Description: Overnutrition: 40% higher lipid consumption per day than required
Study NCT06193668 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Normocaloric macronutrient-balanced nutrition
Description: Normocaloric, macronutrient-balanced nutrition:~Calories requirement for weight maintenance \[(kcal/d) 55% carbohydrates, 15% proteins, 30% fat\]
Study NCT06403969 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Applied Behavior Analysis
Description: Applied Behavior Analysis focusing on nocturnal awakenings. It starts with identification of target behaviors and goals. A functional analysis is conducted to analyze the underlying function of a behavior in connection to the problem. A treatment plan is formulated, including strategies to achieve the goals, and methods to evaluate. Families receive education sleep hygiene. Adaptations focus on antecedents and consequences, with an emphasis on positive reinforcement of favorable behaviors. Various components of Cognitive Behavioral Therapy may be applicable. These include changes in sleep environment, stimulus control, bedtime routines with visual support and prompting. Sleep restriction and bedtime fading are included. Modified extinction techniques with parental presence can be applied, gradually phasing out parental immediate presence. The intervention continues until goals are achieved or for a maximum of 8 sessions (each lasting up to 60 minutes) spread over 8 weeks.
Study NCT05002075 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: m-health cardiac rehabilitation
Description: Participants randomized to m-Health cardiac rehabilitation will receive a 24-week home-based exercise program delivered via a previously validated, commercially available smartphone platform called Movn (Moving Analytics, California). This app includes a patient-facing iOS and Android compatible smartphone app and an integrated hospital-facing online dashboard for remote monitoring and care coordination by a trained coach
Study NCT05529797 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Veovita-VR
Description: Veovita-VR is a VR intervention with positive emotional stimuli and positive behavioral activation designed to reduce depressive symptoms in people with at least moderate depressive symptoms. In the VR session, the participants stay in a beautiful environment (island, sandy beach, beautiful scenery). They can engage in activities that are perceived as positive (climbing, treasure hunting, listening to music, building sandcastles). The session has a length of approx. 30 minutes. Participants are free to continue to engage with any treatment they require during the duration of the study.
Study NCT05300763 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: senofilcon A prototype
Description: Test
Study NCT05300763 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dailies Total 1
Description: Control
Study NCT05987410 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nordic Walking (NW)
Description: The experimental group will carry out NW sessions three times a week for 12 weeks, supervised by a NW instructor and under the control of a cardiologist. The duration of each NW session will initially be 90 minutes: 10 minutes of warm-up, 60 of NW, and 15 minutes of cool-down. The intensity of the course will be gradually increased each week, starting at 70 to 85% of the heart rate (HR) reserve. It will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.
Study NCT05987410 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Rehabilitation (SR)
Description: The second group will follow a standard rehabilitation program with an initial cardiological prescription and supervised by physiotherapists, carried out 5 days a week with sessions lasting 40 minutes, including 5 minutes of warm-up up), 30 min of aerobic physical activity on a conveyor belt or cycle ergometer and 5 minutes of cooling down (cool down). The intensity of your aerobic activity will gradually increase each week, starting at 70 to 85% of HR reserve. It will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.
Study NCT05987410 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cardiological Counselling (CC)
Description: The third group of participants will receive cardiological counselling with indications of unsupervised aerobic physical activity. The group will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.
Study NCT05766046 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: early lung cancer detection
Description: standard treatment for early lung cancer detection with LDCT at one or two years interval
Study NCT05766046 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: blood test
Description: blood analysis for microRNA and other biomarkers detection