AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05925270 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: mhGAP-Standard
Description: Four in-person sessions with up to two booster sessions following the principles of World Health Organization's Mental Health Gap Action Programme (mhGAP).
Study NCT04925921 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SR-1 Laser
Description: 3-4 treatments at 4-6 week intervals
Study NCT05156801 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ArchSinus stent
Description: Post FESS unilateral placement of the ArchSinus stent into the randomized ethmoid sinus cavity.
Study NCT05156801 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ArchSinus stent
Description: Post FESS unilateral placement of the ArchSinus stent into the randomized ethmoid sinus cavity.
Study NCT04708184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG3970 oral solution
Description: GLPG3970 for oral administration
Study NCT04708184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG3970 tablet
Description: GLPG3970 for oral administration
Study NCT05530967 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TT
Description: This intervention uses questionnaire at three-time intervals (i.e., days 5, 10, and 30) and abstraction of PAP use data (days 1 - 35). Consecutive adults with moderate-severe OSA and recommended to PAP treatment will be invited to the study. Once the patient has been prescribed PAP therapy a research associate will call the patient before receiving their new PAP device. The research associate will utilize an IRB approved telephone script to discuss study details, conduct eligibility screening (inclusion/exclusion criteria), and to ask whether the patient is interested in participating.~The research associate will then send the patient an IRB approved digital information sheet. The information sheet will provide the patient an option to mark Yes if they are willing to participate in the study or No if they are not willing. Patients who indicate their willingness to participate will receive the Triage Tool in accordance with the study protocol.
Study NCT05530967 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VE
Description: A randomly selected sub-group of participants (n=30) will also receive an animated education video that provides targeted information and encouragement for self-managing your PAP problem(s). Patients in this sub-group will be asked to view a maximum of 2 different videos that are less than 2 minutes in duration. These videos are aligned with practice guideline recommendations for addressing PAP problems early in treatment. The videos will be sent digitally from Somnoware™.
Study NCT04770090 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood samples
Description: Peripheral blood samples at the beginning of surgery, after pneumoperitoneum creation and uterine pedicles coagulation.
Study NCT05861999 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: risdiplam
Description: Participants will receive risdiplam orally at the currently approved dose. The dose should be adapted for weight and age.
Study NCT06343961 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraoperative Fluorescein Angiography
Description: Targeted laser photocoagulation under the guidance of intraoperative fluoroscopy
Study NCT04669080 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Health care provider cost navigation training
Description: Health care providers and asthma educators in a pediatric asthma clinic will receive an online training about the importance of cost of care conversations, how to start cost of care conversations with families, how to refer families to cost navigation resources, and how to lead asthma specialty care teams in cost navigation.
Study NCT06279585 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy
Description: Health education sessions and combined therapeutic exercise sessions, based on muscular strength training and cardiorespiratory endurance.
Study NCT06287424 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Aged Garlic Extract
Description: Subjects will be instructed to continue using their regular home oral hygiene products until the Product Distribution Visit (Visit 2). They will also be instructed not to add or change any of their regular home oral hygiene products during that time.
Study NCT06287424 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05259046 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Menaquinone-7 (MK-7) tablet (333 µg)
Description: One MK-7 tablet containing 333 µg MK-7 per day
Study NCT05259046 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablet
Description: One placebo tablet per day
Study NCT06201195 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Adductor canal blockade
Description: VAS, VAS move, incision place pain for up and down to patella, drain place pain, motor strenght for femoral nerve and siyatic nerve muscles, side effects, first analgesic requirement time, opioid requirement, other analgesics
Study NCT06201195 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Distal adductor canala blockade and anterior cutaneus nerve blockade
Description: VAS, VAS move, incision place pain for up and down to patella, drain place pain, motor strenght for femoral nerve and siyatic nerve muscles, side effects, first analgesic requirement time, opioid requirement, other analgesics
Study NCT05541692 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Sleep Hygiene Toolkit
Description: The sleep hygiene toolkit includes multiple resources including assistive devices (ie. eye masks and ear plugs), sensory-based tools (ie. aromatherapy, music, meditation, and breathing techniques), cognitive behavioral therapy (CBT) activities (ie. addressing anxiety and worry), and education and training on sleep hygiene.
Study NCT04376346 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Native WYSE CHOICES
Description: Native WYSE (Women, Young, Strong, and Empowered) CHOICES (Changing High-risk alcohOl use and Increasing Contraception Effectiveness Study) is an alcohol-exposed pregnancy prevention program that translates CHOICES, an evidence-based targeted intervention, into an mHealth universal intervention for young urban American Indian/Alaska Native (AI/AN) women ages 16-20.
Study NCT04197297 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: CT and MRI Scans
Description: CT and MRI scans will occur before and after radiation therapy.
Study NCT06080113 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Focal Brachytherapy
Description: Targeted focal brachytherapy is an image-guided technique, where the radioactive source is placed only, and directly into the cancerous area of the prostate. The aim is to preserve the normal surrounding prostate gland tissue to limit treatment-related side effects to the adjacent anatomical structures. A multiparametric prostate MRI is used to identify, localize, and delineate the intraprostatic PCa tumour lesion and plan treatment. A specialized MRI-ultrasound image-fusion software combines the MRI-images with dynamic ultrasound performed in the operating room and is used to focally guide the placement of the radioactive source in the prostate cancer (PCa) tumour focus based on focal dosimetry calculations. A safety margin around the tumour is applied where it is possible to account for MRI tumour volume underestimation, microscopic spread, and treatment uncertainties.
Study NCT05224622 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: VOX
Description: Breath exhalation into the mouthpiece of the VOX breath diagnostic device.
Study NCT05734547 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stepping Together for Children after Trauma (ST-CT)
Description: ST-CT is Step One of Stepped Care CBT for Children after Trauma (previously called Stepped Care Trauma-focused Cognitive Behavioral Therapy; Salloum et al., 2014). It consists of five components: psychoeducation, stabilization, trauma narrative, in-vivo exposures and consolidation. The parent and child have 11 at-home-meetings and complete tasks in a workbook, Stepping Together (from the Preschool PTSD Treatment by Michael Scheeringa et al), over 6-9 weeks. In addition, there are weekly calls and five sessions with the therapist. Children who meet responder-criteria (i.e., no more than four symptoms of PTSS) continue to a 6-week maintenance phase, after which treatment is complete if the child still meets responder criteria. For those who do not meet responder-criteria, or are not able to complete the workbook, the responsibility for the treatment is transferred from the municipal service level to the corresponding child and adolescent mental health service (BUP).
Study NCT05734547 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Therapists in the control group will provide the treatment they usually provide, and develop a treatment plan in collaboration with the parents. This may consist of individual sessions with the child, parent sessions, group treatment, meetings with the school and other collaborating services, or referral to the second line mental health centres (BUP).
Study NCT06575621 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support program
Description: education, medical navigation, exercise
Study NCT06064682 — intervention group
Intervention type: OTHER
Intervention: standard of care biopsy
Description: Image-guided or surgical biopsy of the lesion that is suspected to be osteosarcoma in a patient with localized disease (Group 1)
Study NCT04786262 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VX-880
Description: Infused into the hepatic portal vein.
Study NCT06066710 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Propranolol will be given on a titration schedule in which participants will begin with small doses of the drug and increase to a larger dosage over the course of three weeks. Propranolol will be taken for a total of 9 weeks.
Study NCT06066710 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Magnetic Resonance Imaging (MRI)
Description: Magnetic Resonance Imaging (MRI) will be performed at 3 Tesla and 7 Tesla, for both propranolol and placebo arms.
Study NCT06066710 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging (MRI)
Description: Magnetic Resonance Imaging (MRI) will be performed at 3 Tesla and 7 Tesla, for both propranolol and placebo arms.
Study NCT06066710 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be given on the same schedule as the propranolol regime.
Study NCT06064682 — intervention group
Intervention type: OTHER
Intervention: standard of care biopsy
Description: Image-guided or surgical biopsy or excision of the lesion that is suspected to be recurrent or metastatic osteosarcoma (Group 2).
Study NCT05909696 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rocuronium
Description: Advanced intravenous injection of rocuronium before the succinylcholine injection
Study NCT04726267 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Wide-field optical coherence tomography
Description: Merged 4 images of wide-field optical coherence tomography, 2 images of vertical scan and 2 images of horizontal scan.
Study NCT05786261 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: experimental group MIRT
Description: Task 1a: Assessing the effect of MIRT on cortical plasticity tested with rPAS Task 1b: Assessing the effect of MIRT on structural cortical plasticity and brain connectivity tested with MRI Task 1c: Assessing the effect of MIRT on movement-related beta modulation Task 1d: Assessing the effects of MIRT on motor skills formation with reaching tasks Task 1e: Assessing the effects of MIRT on EEG correlates of motor skills formation Task 2a: Assessing the effect of MIRT on muscle synergies during gait Task 2b: Assessing the effect of MIRT on muscle synergies during reaching movements Task 3a: Assessing the effect of MIRT on sleep microstructure
Study NCT05786261 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EEG task rTMS, fMRI
Description: EEG task rTMS, fMRI
Study NCT05786261 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EEG task rTMS, fMRI
Description: EEG task rTMS, fMRI
Study NCT06513221 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy, Bevacizumab, Adebrelimab
Description: Adebrelimab: 1200mg，q3w Bevacizumab: 7.5mg/kg，q3w Fruquintinib: 4mg po d1\~d14, q3w Chemotherapy: XELOX/mXELIRI: conventional dose
Study NCT06480929 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Contrast TTE procedure, the SonoVue ultrasound agent
Description: The intervention involved using contrast-enhanced transthoracic echocardiography (TTE) to improve the detection of left ventricular thrombus in patients with anterior ST-elevation myocardial infarction (STEMI).
Study NCT05553379 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: FeNO measurement
Description: FeNO measurement at each visit
Study NCT05506332 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax and 6-mercaptopurine
Study NCT05506332 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6-mercaptopurine
Description: Venetoclax and 6-mercaptopurine
Study NCT05702905 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin Hydrochloride 500 MG
Description: Metformin oral tablet (500mg per tablet) will be administered in a dose increasing mode: the initial dose will be 500mg twice daily, which will be increased to 1000mg twice daily after two weeks, and then maintained until the end of treatment in total 12 weeks.
Study NCT05702905 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide, 1.34 mg/mL
Description: Inject semaglutide subcutaneously once weekly, on the same day each week, at any time of day, in a dose increasing mode: the initial dose of 0.25mg QW (once a week), increased to 0.5mg QW after 4 weeks, and increased to 1.0mg QW after another 4 weeks, and then maintained 1.0mg until the end of treatment in total 12 weeks.
Study NCT05702905 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide, 1.34 mg/mL and Metformin Hydrochloride 500 MG
Description: Both Semaglutide injection and Metformin oral tablet will be administered as described above.
Study NCT05702905 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: calorie-restricted diet
Description: All subjects after randomization will be reviewed and evaluated by a nutritionist, and then will receive diet guidance. The clinical nutritionist will develop a written nutrition plan for each subject. The nutrition plan of this study adopted the method of calorie restriction diet (CRD) to develop a diet, which required 83.68 kJ/kg of energy per day, 1.2 g/kg of protein per day, 40%\~55% of carbohydrate energy supply ratio, and 20%\~30% of fat energy supply ratio, to ensure the intake of vegetables, fruits and other rich dietary fiber, and drinking more than 1.5 L per day. The nutritionist will explain the method of food exchange in detail to enrich the food types of patients. The diet diary will be distributed to each subject, and the subjects will be required to make a return visit once every four weeks, return the diet diary each time, and receive guidance according to their compliance.
Study NCT05702905 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: calorie-restricted diet
Description: All subjects after randomization will be reviewed and evaluated by a nutritionist, and then will receive diet guidance. The clinical nutritionist will develop a written nutrition plan for each subject. The nutrition plan of this study adopted the method of calorie restriction diet (CRD) to develop a diet, which required 83.68 kJ/kg of energy per day, 1.2 g/kg of protein per day, 40%\~55% of carbohydrate energy supply ratio, and 20%\~30% of fat energy supply ratio, to ensure the intake of vegetables, fruits and other rich dietary fiber, and drinking more than 1.5 L per day. The nutritionist will explain the method of food exchange in detail to enrich the food types of patients. The diet diary will be distributed to each subject, and the subjects will be required to make a return visit once every four weeks, return the diet diary each time, and receive guidance according to their compliance.
Study NCT05441150 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Low dose ketamine infusion
Description: Administering low-dose ketamine infusion to the patient under general anesthesia for Ketamine Group.
Study NCT05441150 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: 0.9% NaCl infusion
Description: Same dose of 0.9% NaCl infusion as the dose of ketamine for Control Group.
Study NCT04710940 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes BOOST
Description: Participants will receive supportive care using technology for DSMT in addition to usual care.
Study NCT04710940 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants will receive usual care for DSMT.
Study NCT05702905 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: physical exercise
Description: All subjects after randomization will be reviewed and evaluated by a trainer, and then will receive guidance of physical exercise.The trainer will formulate an exercise plan for each subject. The exercise plan consists of 30 minutes of moderate and low intensity continuous aerobic exercise every day, with a frequency of 5-7 days/week. The form of exercise can be determined according to personal hobbies, such as fast walking, jogging, climbing, swimming, etc. The exercise diary will be distributed to each subject, and the subjects are required to make a return visit once every four weeks, return the exercise diary each time, and the trainer will provide guidance to the subjects according to their compliance.
Study NCT05702905 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: physical exercise
Description: All subjects after randomization will be reviewed and evaluated by a trainer, and then will receive guidance of physical exercise.The trainer will formulate an exercise plan for each subject. The exercise plan consists of 30 minutes of moderate and low intensity continuous aerobic exercise every day, with a frequency of 5-7 days/week. The form of exercise can be determined according to personal hobbies, such as fast walking, jogging, climbing, swimming, etc. The exercise diary will be distributed to each subject, and the subjects are required to make a return visit once every four weeks, return the exercise diary each time, and the trainer will provide guidance to the subjects according to their compliance.
Study NCT04878172 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TempSure Firm
Description: The TempSure firm will be used on the abdomen for non-invasive lipolysis.
Study NCT04928989 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: convergence dialogue meeting
Description: Digital counceling with convergence dialogue tripartite meeting. will be conducted in accordance with work dialogue for return to work. Workplace dialogue among employee with neck problems, an expert in the work environment, and the immediate manager. The purpose of the conversations is, in open dialogue, to reach a common understanding of the situation and identify possible interventions to maintain or improve the employee´s work ability.
Study NCT04928989 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: convergence dialogue meeting
Description: Digital counceling with convergence dialogue tripartite meeting. will be conducted in accordance with work dialogue for return to work. Workplace dialogue among employee with neck problems, an expert in the work environment, and the immediate manager. The purpose of the conversations is, in open dialogue, to reach a common understanding of the situation and identify possible interventions to maintain or improve the employee´s work ability.
Study NCT05103774 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: T3-T4-TSH
Description: thyroid function tests
Study NCT04644575 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: efanesoctocog alfa (BIVV001)
Description: Pharmaceutical form:Solution for Injection Route of administration: Intravenous
Study NCT06664515 — intervention group
Intervention type: PROCEDURE
Intervention: Ciro Costagliola
Description: invert flap tecnique
Study NCT06341569 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Respiratory breathing techniques group
Description: Target group: subjects in the respiratory breathing techniques group. Program duration: the program lasts for 14 weeks.~Breathing techniques: the program includes various breathing exercises, including:~Diaphragmatic breathing teaches participants to breathe deeply, engaging the diaphragm muscle, which can improve lung capacity and relaxation.~Pursed-lips breathing: this technique involves inhaling through the nose and exhaling slowly through pursed lips, which can help slow down breathing and manage shortness of breath.~Alternate nostril breathing: this technique involves closing one nostril while inhaling and exhaling through the other nostril alternately.~Relaxation techniques: the program incorporates progressive muscle relaxation techniques. This involves progressively tensing and relaxing different muscle groups.~Medical education: topics like the anatomy of the respiratory system, the importance of proper breathing, potential benefits of specific breathing exercises.
Study NCT06671509 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YZJ-1139
Description: Single oral dose, 20 mg tablet
Study NCT02069288 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludrocortisone
Description: 50 µg of fludrocortisone per os
Study NCT02069288 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 tablet of placebo per os
Study NCT05346432 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: PS23
Description: PS23 belongs to Lactobacillus paracasei group.Probiotic capsules contain 10 billion CFU (colony forming units) of PS23