AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06032780 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eccentric Resistive Training + Aerobic training Group
Description: Eccentric Resistive training includes upper limb (biceps and triceps) and lower limb large muscle training (quadriceps and hamstrings) 2 sets of 12 repetitions (reps) for each group of muscles in lengthened position for eccentric training in approx. 20 minutes (min). Intensity will be based on 1 repetition maximum (1RM) starting from 20% of (1RM) and its intensity in percentage will be progress by 10% after every two weeks. Stair descending training and squatting position and eccentric hamstring curls with weights at ankle for lower limb eccentric training progressive as per tolerance in response to modified Borg scale (with cut off of showing dyspnea of 4 somewhat hard) and Numeric Pain rating scale (with cut off of showing 7 on scale, crossing moderate pain) . (approx. 20 min).~+ Aerobic training as a control will be given to this group as well for approximately 30 minutes per session.
Study NCT06032780 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Training + Aerobic training Group
Description: Resistive training (concentric) includes Upper limb (biceps and triceps) and lower limb large muscle training (quadriceps and hamstrings), 2 sets of 12 reps for each group of muscles in approx. 30 min. Intensity will be based on 1 repetition maximum (1RM) starting from 20% of (1RM) and its intensity in percentage will be progress by 10% after every two weeks. Stair climbing training and quadriceps training + standing hamstring curls with weight at ankle for lower limb concentric training progressive as per tolerance in response to modified Borg scale (with cut off of showing dyspnea of 4 somewhat hard) and Numeric Pain rating scale (with cut off of showing 7 on scale, crossing moderate pain)~+ Aerobic training as a control will be given to this group as well for approximately 30 minutes per session.
Study NCT06032780 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic training Group
Description: Aerobic training as a control will be given to this group as well for approximately 60 minutes per session. Aerobic training exercise will be completed via a ergometer/stationary cycle; type will be continuous aerobic exercise and intensity of 60% of max HR (or peak VO2) in HF individuals.
Study NCT05755841 — intervention group
Intervention type: OTHER
Intervention: Outpatient management of preterm prelabor rupture of membranes
Description: Patients who will be managed as outpatients will be discharged after 48 hours of hospitalization with the following management:~* Twice weekly fetal cardiotocography.~* Complete blood count once a week.~* A weekly clinical and ultrasound examination.
Study NCT05755841 — intervention group
Intervention type: OTHER
Intervention: Inpatient management of preterm prelabor rupture of membranes
Description: In the Inpatient Care Policy group, the same protocol as outpatient group will be applied, but the patient will not be discharged until delivery.
Study NCT05723185 — intervention group
Intervention type: OTHER
Intervention: Outpatient visit
Description: Patients will be seen and treated at the outpatient clinic like in the usual care
Study NCT06379737 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-systemic Rehabilitation
Description: Patients in group A underwent a 5-week rehabilitation cycle with two weekly sessions, totaling 10 sessions, in a health resort setting. The patients underwent treatments at two health resort facilities located in the Euganean Basin, Veneto, Italy, equipped with pools of the same depth, size, and water type. Each session was structured into four components:~1. thermal mineral-rich aerosol therapy (10 minutes);~2. dryland motor, respiratory, and proprioceptive rehabilitation in the gym (30 minutes);~3. mineral-rich aquatic aerobic, strengthening, and balance exercises (30 minutes);~4. cognitive enhancement interventions (30 minutes). Inhalation treatments and aquatic exercises utilized thermal mineral-rich water, specifically salsobromoiodic water, naturally springing at approximately 80°C and used in pools at a temperature of around 36°C. The chemical-physical properties of the thermal mineral-rich water employed are reported in Table I.~Patients in group B underwent a 5-week rehabilit
Study NCT06379737 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Multi-systemic Rehabilitation
Description: Patients in group A underwent a 5-week rehabilitation cycle with two weekly sessions, totaling 10 sessions, in a health resort setting. The patients underwent treatments at two health resort facilities located in the Euganean Basin, Veneto, Italy, equipped with pools of the same depth, size, and water type. Each session was structured into four components:~1. thermal mineral-rich aerosol therapy (10 minutes);~2. dryland motor, respiratory, and proprioceptive rehabilitation in the gym (30 minutes);~3. mineral-rich aquatic aerobic, strengthening, and balance exercises (30 minutes);~4. cognitive enhancement interventions (30 minutes). Inhalation treatments and aquatic exercises utilized thermal mineral-rich water, specifically salsobromoiodic water, naturally springing at approximately 80°C and used in pools at a temperature of around 36°C. The chemical-physical properties of the thermal mineral-rich water employed are reported in Table I.~Patients in group B underwent a 5-week rehabilit
Study NCT06042400 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Written Exposure Therapy
Description: An innovative written exposure therapy intervention that addresses psychosocial needs commonly experienced by patients with late stage cancers.
Study NCT06292091 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Captopril 12.5 Mg
Description: 12.5 mg of captopril
Study NCT06292091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Captopril 12.5 Mg
Description: 12.5 mg of captopril
Study NCT06292091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium bicarbonate 4 G
Description: 4 g of sodium bicarbonate
Study NCT06292091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Torsemide 20 MG
Description: 20 mg of torsemide
Study NCT04820972 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antiplatelet Agents
Description: using antiplatelet agents in 3 days after surgery
Study NCT05217199 — intervention group
Intervention type: OTHER
Intervention: Measurements
Description: Demographic information of infants and parents, prenatal, postnatal and natal risk factors, Magnetic Resonance Images (MRI), General Movements (GMs) evaluations of babies with Prechtl method from NICU will be recorded. Video recordings for General Movements (GMs) analyzes with the Prechtl method will be taken at postterm 12th to 20th weeks. The infants' sensory processing (general, auditory, visual, tactile, movement, oral) will be evaluated with the adjusted Infant Sensory Profile-2 (ISP-2) family scale, which will be filled in by their mothers at the 3rd month. For motor assessments, the postterm corrected 3 month Hammersmith Infant Neurological Examination (HINE) will be used. A pediatric neurologist who was blinded to all testing made the diagnosis of CP in a 2-year-old child based on neuroimaging and clinical tests.
Study NCT04774731 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole Body Vibration
Description: Receiving WBV training three times a week before initiation of dialysis sessions for 12 weeks. Subjects stand on a platform of WBV for 3 minutes in every training session.
Study NCT05802654 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: The participants enrolled will receive single fraction of ultra-high dose SBRT(30Gy/1F).
Study NCT04667377 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 456906
Description: BI 456906
Study NCT04667377 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05018247 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Revascularization by Coronary Artery Bypass Graft or Percutaneous Coronary Intervention
Description: Urgent revascularization via CABG or PCI combined with Optimal Medical Treatment
Study NCT05018247 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Revascularization by Coronary Artery Bypass Graft or Percutaneous Coronary Intervention
Description: Urgent revascularization via CABG or PCI combined with Optimal Medical Treatment
Study NCT05623930 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: laser acupuncture
Description: In fatty liver diseased patients which their number will be 30 patients, a 3-session/week application of 2-minute laser (for 3 months) on acupoint number 25,40,36 of stomach meridian, acupoints number 3 and 14 of liver meridian, acupoint number 6 of spleen meridian,acupoint number 9.12,4 of conception vessel meridian, acupoint number 14 of governor vessel meridian, acupoint number 4, 11 of large intestine meridian, acupoint number 34 of gall bladder meridian
Study NCT05623930 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: wet cupping
Description: in this fatty liver diseased patients which their number will be 30, cupping (with scarification) or wet cupping will be applied at the first day and the day number 14 in the month for three successive months. cupping (with scarification) or wet cupping will be applied on urinary bladder acupoint 17 (on the both sides) and governosal vessels acupoints 12,13,and 14.
Study NCT06372548 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Find You! Cure My Animal Friends
Description: Introduced cognitive evaluation theory combined with masking therapy to develop a gamified product that guides amblyopic children to develop habits for the purpose of rehabilitation training.
Study NCT06372548 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DuoBao Vision Training System
Description: This is a visual training app where participants are required to complete several training tasks.
Study NCT05211336 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Obinutuzumab 1000 mg IV (intravenous) days 1 and 2 for a maximum of 6 cycles every 21 days (each cycle is 21 days)
Study NCT05211336 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone 100 mg PO (by mouth) daily days 1-7 for a maximum of 6 cycles every 21 days (each cycle is 21 days)
Study NCT05211336 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide 10 or 15 mg PO (by mouth) on days 1-14 for 1 cycle (21 days); followed by Lenalidomide 10 or 15 mg PO daily days 1-14 for a maximum of 6 cycles every 21 days (each cycle is 21 days)
Study NCT05211336 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax 800 mg PO (by mouth) on days 1-14 for a maximum of 6 cycles every 21 days (each cycle is 21 days)
Study NCT05211336 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibrutinib
Description: Ibrutinib 560 mg PO (by mouth) daily days 1-14 for a maximum of 6 cycles every 21 days (each cycle is 21 days)
Study NCT05319184 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial Release Technique and Kinesiology Taping
Description: Myofascial release is a manual release technique that increases the elasticity and glide between soft tissue layers, reduces this increased muscle activity and pain intensity. Myofascial release is usually characterized by prolonged mechanical forces exerted directly or indirectly on the limited fascial layers with low load. Following the direction of the fascial restraint, the therapist's hands slowly maintain the stretch and allow the fascia to relax on its own.~Kinesio Taping is a non-invasive, painless and less time consuming method with fewer side effects. It is an elastic-cotton adhesive tape that is latex-free and can be used on any joint or muscle. It can stretch significantly (130-140% of its original length), which reduces mechanical movement limitations and mimics skin in thickness and elasticity. It is used in the treatment of LBP to reduce muscle tone and stiffness as a rehabilitative taping technique designed to support the body's natural healing process.
Study NCT04628338 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IFN-γ (interferon gamma-1b) injection
Description: Dosage form: 100 mcg (2 million International Units) per 0.5 mL solution, administered subcutaneously Dose regimen: three times weekly (Weeks 0-7), once weekly (Weeks 8-12)
Study NCT06261073 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: blood sample and tissue biopsy
Description: Serum level of Cathepsin L: 3 cm of blood will be taken on EDTA tubes from patients and control subjects and will be analyzed by double antibody sandwich enzyme-linked immune-sorbent assay (ELISA) to assess the level of CTSL in blood samples. Tissue expression of Cathepsin L: 5 mm punch biopsies will be taken under local anesthesia from lesions and from the adjacent normal skin of patients (from the lesional and peri-lesional sites). Also, skin biopsy of normal skin will be taken from healthy volunteers. The specimen of skin will be immediately placed in a formalin saline, and then immune-histochemical evaluation will be done to evaluate the CTSL expression in tissue.
Study NCT05840926 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic Streptococcus salivarius K12
Description: Oral 1 billion CFU of Probiotic Streptococcus salivarius K12
Study NCT05840926 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No probiotic supplementation
Description: Children who did not receive any probiotic supplementation
Study NCT06248164 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: We will not carry out any type of intervention, just observe the behaviors and health parameters of parents and children.
Study NCT06029075 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tACS Sham
Description: Sham tACS will applied to the brain through the scalp for 20 minutes.
Study NCT06029075 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tACS 10Hz
Description: 10Hz tACS will applied to the brain through the scalp for 20 minutes.
Study NCT06029075 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tACS 20Hz
Description: 20Hz tACS will applied to the brain through the scalp for 20 minutes.
Study NCT05836142 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: progressive pressure release
Description: Bilateral progressive pressure release in latent trigger points of the Flexor digitorum Brevis Muscle
Study NCT06240221 — intervention group
Intervention type: DEVICE
Intervention: Elevation Spine Saber-C System
Description: Device: Elevation Spine Saber-C System Elevation Spine Saber-C System will be fixated between C2 through T1 according to surgeon standard of care at clinical practices through the United States.
Study NCT05377268 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LH Protocol
Description: Patients will be randomized and data interpreters will be blinded to two, randomized, alternating 14-day protocols where the patients will be advised by the nurse educator verbally to inject insulin in sites of subclinical lipohypertrophy
Study NCT05377268 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: LH Protocol
Description: Patients will be randomized and data interpreters will be blinded to two, randomized, alternating 14-day protocols where the patients will be advised by the nurse educator verbally to inject insulin in sites of subclinical lipohypertrophy
Study NCT05241392 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: B7-H3-targeting CAR-T cells
Description: Patients will be treated with anti-B7-H3 autologous CAR-T cells that are delivered into the intracranial tumor resection cavity or ventricular system using an Ommaya device.
Study NCT06020677 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: L-WebTIPS
Description: This mobile health application includes cultural adaption and grounding of a previously developed and tested tailored mHealth intervention, WebTIPS. LWebTIPS is a culturally adapted mHealth intervention that is aimed at the child and parent and strives to improve clinical outcomes and patient experience of Latinx children. Tailoring variables include: Simpatia, Religiosity and Familism.
Study NCT05489835 — intervention group
Intervention type: BEHAVIORAL
Intervention: Nutritional counseling
Description: Nutritional counseling
Study NCT04971291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AXS-05
Description: AXS-05 taken twice daily for 6 weeks
Study NCT04971291 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupropion SR
Description: Bupropion taken twice daily for 6 weeks
Study NCT05230589 — intervention group
Intervention type: DRUG
Intervention: Oral semaglutide
Description: Patients will be treated with commercially available oral semaglutide according to local label and to routine clinical practice at the discretion of the treating physician. The decision to initiate treatment with commercially available oral semaglutide has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician based on local label before and independently from the decision to include the patient in this study.
Study NCT05217121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus Lumborum Block
Description: The block procedure will be applied after the surgery and before extubation with patients in the prone position by using US (Vivid Q, GE Healthcare, US). Under aseptic conditions, the probe will be covered with a sterile sheath and a 22G, 80 mm block needle (Braun Stimuplex Ultra 360, Germany) will be used. After visualizing the abdominal muscles, the needle will be punctured and 5 ml of saline will be injected into the postero-lateral border of the quadratus lumborum muscle. After the block location is confirmed, 15 ml of 0.25% bupivacaine will be injected. The same process will be applied to the opposite side (30 ml totally).
Study NCT05217121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Modified-thoracolumbar interfascial plane block
Description: US probe will be placed vertically at the L3 vertebrae level. After visualizing the hyperechoic shadow of the spinous process and interspinous muscles as an anatomical guide point, the probe will be moved forward to the lateral to visualize the longissimus and iliocostal muscles. Between these muscles, block needle will be inserted within in plane technique in a medial-to-lateral direction in the interfascial plane. Once the needle tip will be placed within the interfacial plane and after careful aspiration to rule out intravascular needle placement, 2 mL of saline will be injected to confirm the proper injection site, and then a dose of 0.25% bupivacaine 15 mL will be injected in each side (30 ml totally).
Study NCT06000995 — intervention group
Intervention type: OTHER
Intervention: Survey Questions
Description: Thirty questions generally consist of three parts; In the first part, there are 8 questions containing the personal information of the doctors (age, gender, title, institution, etc.). In the second part, 13 questions were included in order to make a general assessment such as the sedative agents used by the doctors before and during the bronchoscopy procedure and the satisfaction with the sedative method used. In the third part, 9 questions were given to determine the preferred follow-up methods during the procedure.
Study NCT05699161 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Adipose-derived stromal vascular fraction cells
Description: Published minimal clinically important differences (MCID) for PDQ-39; MDS-UPDRS; and levo-dopa equivalent dose and changes in the levels of blood proteins (L-1beta, IL-2, IL-6, IL-10, and TNF-alpha) in 10 patients after 12 months of treatment with SVF cells.
Study NCT04957342 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: amnion-chorion membrane
Description: allograft to be placed on palate
Study NCT04957342 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sutures
Description: Sutures (e.g. interrupted, crisscross compression) to be placed on palate
Study NCT06174844 — intervention group
Intervention type: OTHER
Intervention: No intervention applied
Description: No intervention applied: data will only be collected in the indicated sampling periods from patients admitted to the participating hospitals.
Study NCT05327413 — intervention group
Intervention type: OTHER
Intervention: CT and MRI
Description: CT and MRI were conducted to measure the femoral external rotation
Study NCT05449626 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment
Description: The Standardized Mini-Mental Test and Clinical Dementia Rating Scale will be administered by the physician to the healthy individuals with dementia to be included in the study.
Study NCT06158542 — intervention group
Intervention type: PROCEDURE
Intervention: Spinal Anesthesia
Description: After standard monitoring, the patient is placed in a sitting position for site marking and administration of anesthesia. The line connecting the upper border of the right and left iliac crests through conventional palpation of anatomical landmarks (Tuffier line) is identified as the entry point at the L3-L4 interspinous space or L2-L3 interspace. For patients in whom spinal entry is successful, spinal anesthesia is provided with the appropriate dose and types of local anesthetics (intrathecal 10-12 mg bupivacaine with the addition of 15-25 mcg fentanyl). After completing the procedure and placing the patient in the supine position, the block level is determined 10 minutes post-procedure using the ice test/pinprick test. Blocks reaching the T4-T6 level are considered successful.
Study NCT06158542 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood Sampling
Description: Preoperatively, syndecan-1 serum levels will be investigated from the blood sample taken before cesarean section.
Study NCT05376215 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Experimental hearing aid
Description: This hearing aid is a receiver-in-canal style hearing aid which can be programmed and adjusted by proprietary software and by use with a mobile application.
Study NCT05376215 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental hearing aid
Description: This hearing aid is a receiver-in-canal style hearing aid which can be programmed and adjusted by proprietary software and by use with a mobile application.