AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06694506 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biological Sample
Description: Clinical examination and blood test. The clinical examination and blood test are considered standard-of-care as they could be performed annually or bi-annually as part of an adult GHD follow-up. Subsequently, the data will be collected directly from the patient's chosen physician.
Study NCT06688539 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Varenicline Pill
Description: In this study, all participants will be administered active medication for a 12 week treatment period. The standard dose titration schedule will be used, which includes 0.5 mg once per day (q.d.) on Days 1-3, 0.5 mg twice per day (b.i.d.) on Days 4-7, and 1.0 mg b.i.d. starting on Day 8. Dosing of 2.0 mg per day will be maintained for the next 11 weeks, for a total of 12 weeks of active treatment for all study participants.
Study NCT06688539 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Contingency management
Description: Contingency management procedures will be implemented and financial incentives will be provided at weekly visits contingent on e-cigarette abstinence verified through urinary qualitative cotinine (starting at Week 2). A set amount of $20 per study visit will be delivered based on a negative qualitative urinary cotinine result.
Study NCT06688539 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Counseling
Description: Psychosocial counseling will be administered by trained research staff leading up to the target quit date and throughout the study.
Study NCT06687044 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep restriction
Description: Go to bed before 23pm
Study NCT06687044 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stimulation control
Description: Avoid drugs, alcohol, caffeine, and nicotine
Study NCT06687044 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive therapy
Description: Listen to 30 minutes of soothing music every night for 8 weeks
Study NCT06687044 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Sleep principles discussion
Description: The principles of sleep hygiene are discussed, but without the application of stimulus control or sleep restriction
Study NCT06688175 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMRT combined with lobaplatin-based concurrent chemotherapy
Description: IMRT combined with two cycles of lobaplatin-based concurrent chemotherapy
Study NCT05564182 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High intensity laser therapy
Description: HILT will be applied to the patients five times a week for a period of three weeks and one session per day for a total of 15 sessions by a physical therapy technician who is experienced in using a laser device (BTL-6000 high intensity laser 12 W, Stevenage, Hertfordshire, England). It will be used in the rotator cuff muscles area in two stages, Phase I and Phase II. For analgesic effect in phase I. Phase II will also be applied for the biostimulation effect.
Study NCT05564182 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Exercise
Description: Therapeutic Exercise As therapeutic exercise program; A multidisciplinary stroke rehabilitation program will be implemented in the presence of a specialist physiotherapist. In addition, a therapeutic exercise program including passive, actively supported and active ROM exercises, stretching, strengthening and mobilization exercises will be applied to all patients by physiotherapists according to the level of pain and limitation.It was planned to implement a total of 15 sessions 5 days a week for 3 weeks, for approximately 30 minutes.
Study NCT05564182 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Exercise
Description: Therapeutic Exercise As therapeutic exercise program; A multidisciplinary stroke rehabilitation program will be implemented in the presence of a specialist physiotherapist. In addition, a therapeutic exercise program including passive, actively supported and active ROM exercises, stretching, strengthening and mobilization exercises will be applied to all patients by physiotherapists according to the level of pain and limitation.It was planned to implement a total of 15 sessions 5 days a week for 3 weeks, for approximately 30 minutes.
Study NCT05420987 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Jing Si herbal tea liquid packet
Description: Jing Si herbal tea includes eight Taiwan native-grown herbs: such as mugwort leaves, fish needle grass, Ophiopogon japonicus, platycodon, perilla leaves, chrysanthemum, and licorice
Study NCT05420987 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Jing Si herbal tea liquid packet
Description: Jing Si herbal tea includes eight Taiwan native-grown herbs: such as mugwort leaves, fish needle grass, Ophiopogon japonicus, platycodon, perilla leaves, chrysanthemum, and licorice
Study NCT06686212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sensory re-education+ strengthening exercises+ kinesio taping
Description: Sensory re-education. Splinting: as constant maintained touch with wrist holding in neutral position for 15 minutes.~Topical anesthesia spray on affected area for 10 minutes. Massage: apply massage over sensitive areas with same speed and pressure, then the light pressure with cotton, velvet, terry cloth, polyester and wool over sensitive area for 10 minutes.~PNF using upper extremity (D2) pattern including shoulder extension, adduction, internal rotation, wrist and fingers flexed and wrist ulnar deviated. 10-15 repetitions for 5 minutes.~Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions of each exercise for 20 minutes.~Kinesio taping: Taping will be applied twice a week for 12 weeks.
Study NCT06686212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neural mobilization+ Strengthening exercises+ Kinesio taping.
Description: The median nerve is mobilized through wrist flexion and extension with elbow straight and palm facing up.~Wrist flexion and extension with elbow flexed to 90 degrees with palm facing up 10-15 repetitions.~Wrist flexors stretch with extended arm and palm facing down 10-15 repetitions. Straight fist: hold your hand up with fingers straight. Full fist: bend your fingers to form a full fist. Median nerve stretch and wrist extension exercises for 30 minutes. Free the bird exercises, busy bee flexion shape of Z exercises and wall stretch exercise. (10-15 repetitions) for 10 minutes.~Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions each for 20 minutes.~Kinesio taping: The taping will be applied twice a week for 12 weeks.
Study NCT05019183 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Physical training
Description: The subjects will perform 6 indoor rower sessions (30 min each, on Day 1, 2, 3, 8, 9 and 10) with a target heart rate zone of 60%.
Study NCT05019183 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical training
Description: The subjects will perform 6 indoor rower sessions (30 min each, on Day 1, 2, 3, 8, 9 and 10) with a target heart rate zone of 60%.
Study NCT05019183 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality
Description: The subjects will be able to move freely in virtual environments while training on the indoor rower.
Study NCT05019183 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Single-photon emission computed tomography (SPECT)
Description: SPECT allows the measurement of cerebral perfusion, reflecting the global synaptic activity, via a 3D acquisition of 20 minutes, 15 minutes after injection of 740 MBq of radiotracers (ECD - Neurolite or HMPAo - Cerestab), with iterative reconstruction. The data will be processed at the voxel scale by the SPM12 software, with analysis of brain connectivity.
Study NCT05019183 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Single-photon emission computed tomography (SPECT)
Description: SPECT allows the measurement of cerebral perfusion, reflecting the global synaptic activity, via a 3D acquisition of 20 minutes, 15 minutes after injection of 740 MBq of radiotracers (ECD - Neurolite or HMPAo - Cerestab), with iterative reconstruction. The data will be processed at the voxel scale by the SPM12 software, with analysis of brain connectivity.
Study NCT05019183 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Metabolomics
Description: This qualitative approach will aim to identify pathways that are not known (or have not been explored) to optimize the chances of detecting metabolites present depending on the group (physical activity coupled or not with VR). This method is favorable for biomarker discovery.
Study NCT05019183 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Metabolomics
Description: This qualitative approach will aim to identify pathways that are not known (or have not been explored) to optimize the chances of detecting metabolites present depending on the group (physical activity coupled or not with VR). This method is favorable for biomarker discovery.
Study NCT04232501 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cirvo Compression device
Description: Patients will wear Cirvo compression device during the surgery, after surgery and will be discharged to home with the device to wear at home as the per study protocol instructions.
Study NCT06040567 — intervention group
Intervention type: OTHER
Intervention: Validity and reliability of outcome measures in polyneuropathy
Description: Patients will be tested, answer patient reported outcome measures, and wear accelerometer at baseline after 2-4 weeks and after 1-2 years.
Study NCT06040567 — intervention group
Intervention type: OTHER
Intervention: Healthy controls
Description: Healthy controls will be tested, answer patient reported outcome measures, and wear accelerometer at baseline visit. There is no follow-up in the healthy control group.
Study NCT05678790 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Passive Stretching
Description: Sustained passive stretching of hamstring, tendo-achilles, and adductors 10 (30 s, with three repetitions, five times per week)
Study NCT05678790 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobilization
Description: Grade four mobilizations is a stretching motion performed at the talocrural joint with anterior-posterior gliding. Mobilization was performed once a day, 6 times a day, and 5 times a week, only on both deformed feet of the older sibling
Study NCT05678790 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle strengthening
Description: Abdominal muscle strengthening exercises were given to both siblings once a day, 10 times a day, 5 times a week. In the supine position, the patients were asked to lie on their knees with the knees flexed. The hip extensors were trained in the prone position on the bed by resisting hip extension
Study NCT05678790 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Balance and Coordination
Description: The following exercises were applied 5 times a week, with 1o repetition once a day.~* Standing on one leg in front of the mirror,~* Tandem walking,~* Rhythmic Dynamic Stabilization,~* Swiss ball sitting (eyes open and closed),~* Counting the alphabet or numbers while marching
Study NCT05044169 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Broncho-Vaxom
Description: administration for 6 months after remmission
Study NCT04751331 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LPS
Description: Lipopolysaccharide (LPS) (0.8ng/kg of body weight; E. coli group O:113)
Study NCT06687837 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: autologous dopaminergic cell implantation
Description: Dopaminergic progenitor cells derived from autologous induced pluripotent stem cells will be injected into the brain in two cohorts of Parkinson's patients, one receiving low dose and the other high dose (4 and 8 million cells, respectively)
Study NCT04751331 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: 0.9% saline administered as an intravenous bolus
Study NCT05484986 — intervention group
Intervention type: OTHER
Intervention: A questionnaire with 47 items
Description: A form consisted of questions on introductory characteristics (age, sex, and class, among others), Big Five Inventory (BFI) to evaluate personality traits, and Management of Workplace Violence Competence Scale for Nursing Students in Areas of Clinical Practice.
Study NCT06390618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise (AE) Group
Description: A total of 24 sessions of aerobic exercise will be performed in 8 weeks, 3 days a week.~For aerobic exercise, a moderate intensity (50-60%) aerobic exercise program will be applied using the karvonen method. According to the aerobic exercise intensity karvonen method, the formula (Maximal Heart Rate (220-years) - Resting Heart Rate) x 50-60% + Resting Heart Rate) will be used. 1-4. week 50%, 5-8. Exercise intensity will be increased by 60% per week.
Study NCT06390618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Combined Exercise (CE) Group
Description: In the combined exercise group, biopsychosocial exercise will be performed in addition to aerobic exercise.~In the combined exercise group, in addition to aerobic exercise (3, 8 weeks, 24 sessions of aerobic exercise per week), 16 sessions of biopsychosocial-based group exercise treatment will be performed 2 days a week for a total of 8 weeks.~BETY approach will be used in group exercise treatment.
Study NCT05942274 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: We propose to validate these smartwatch ECG functions to support FDA submissions
Description: 1) Obtain a simultaneous recording of a Lead I (RA-LA) ECG from the Smartwatch and a clinical standard device (GE Cardiosoft ECG). Subsequent recordings will be acquired from the other models of the Smartwatch as well as a recording utilizing the FDA-cleared KardiaMobile.
Study NCT04910412 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation
Description: Transcranial direct current stimulation will be use for the intervention. Anodal and sham tDCS will be applied in 2 mA through a pair of saline-soaked surface sponge electrode 35 cm square for 20 minute over the primary motor area for modulating the cortical excitability before apply the rehabilitation training
Study NCT04910412 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: transcranial direct current stimulation
Description: Transcranial direct current stimulation will be use for the intervention. Anodal and sham tDCS will be applied in 2 mA through a pair of saline-soaked surface sponge electrode 35 cm square for 20 minute over the primary motor area for modulating the cortical excitability before apply the rehabilitation training
Study NCT06691776 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: online CBCT-guided adaptive radiation therapy using a new software
Description: Patients are treated in the NKI with CBCT-guided online adaptive radiotherapy. While in the clinical workflow one planning CT is used to make the radiotherapy plan, this study treatment creates a new radiotherapy plan on the day of every treatment fraction. Instead of directly irradiating, the radiotherapy plan is adjusted to the anatomy of the day.
Study NCT06302322 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thin Tissues
Description: Patients with thin tissues received implants 10 years ago and are now followed up after 10 years.
Study NCT06691048 — intervention group
Intervention type: OTHER
Intervention: Description of an adult population diagnosed late with a neurodevelopmental disorder
Description: Clinical description during diagnostic interview
Study NCT06694714 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.5 ml lidocaine + epinephrine 1:100,000
Description: 0.5 ml lidocaine + epinephrine 1:100,000, buffered 1/10 with sodium bicarb
Study NCT06302322 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thick Tissues
Description: Patients with thick tissues received implants 10 years ago and are now followed up after 10 years.
Study NCT06694714 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1.0 ml lidocaine + epinephrine 1:100,000
Description: 1.0 ml lidocaine + epinephrine 1:100,000, buffered 1/10 with sodium bicarb
Study NCT06689228 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rational Drug Use Training
Description: Rational Drug Use Training and Tele-monitoring will include information on drugs and their importance, rational drug use, rational drug use in haemodialysis patients, harms of irrational drug use, benefits of rational drug use, obstacles encountered in rational drug use, ways to overcome obstacles encountered in rational drug use, and increasing self-efficacy. The first training is planned to last approximately 30-35 minutes for each patient and the second training (summary training) is planned to last approximately 15-20 minutes. With telemonitoring, reminder messages will be sent to patients' phones at intervals.
Study NCT05722171 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: gdT cell injection targeting B7-H3 chimeric antigen receptor
Description: The subjects, who sign the informed consent forms and been screened by inclusion/exclusion criteria, will be assigned into 1E8, 2E8 and 4E8 CAR-gdT groups in order of sequence. And the subjects will be administered once.
Study NCT05284721 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Peer Navigator for Early Psychosis
Description: The Family Peer Navigator model is theoretical underpinning by the Social-Ecological Model and the Social Cognitive Theory, that incorporates a mixture of evidence- and research-based strategies, to include three key components: 1) Introduction and Assessment; 2) Individual Psychoeducation; 3) Six Brief Check-In
Study NCT05284721 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care Coordination
Description: active control, treatment as usual including services provided by the coordinated specialty care program for first-episode psychosis.
Study NCT06302322 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgically augmented thin tissues
Description: Patients with thin tissues received soft tissue augmentation and implants 10 years ago and are now followed up after 10 years.
Study NCT05679921 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pembrolizumab, pazopanib
Description: Pembrolizumab will be given for a maximum of 2 years i.e. a total of 35 cycles of pembrolizumab with the q3 week dosing. Participants who complete study intervention after 2 years of pembrolizumab can be treated with pazopanib monotherapy based on physician's judgement. The duration of optional pembrolizumab crossover treatment will be maximum of 2 years i.e. a total of 35 cycles of pembrolizumab for patients progressing on pazopanib.
Study NCT04961216 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OPTIMISE
Description: Self-regulation intervention
Study NCT06363435 — intervention group
Intervention type: DEVICE
Intervention: AI-based detection and quantification of suspected tumour/metastases in PSMA PET/CT scans
Description: Tumour burden will be automatically calculated and stored in a database. The result of the AI-based measurements will not involve the handling of the patients
Study NCT05862870 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: painTRAINER
Description: patient self-administered pain management web application
Study NCT05255263 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PIEB
Description: Programmed Intermittent Epidural Bolus with Patient-Controlled Epidural Analgesia
Study NCT05255263 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CEI
Description: Continuous Epidural Infusion with Patient-Controlled Epidural Analgesia
Study NCT04349111 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Intra-operative Radiation Therapy - IORT
Description: Single dose of 20 Gy
Study NCT05625217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Total Body PET/CT Imagin
Description: Total-body PET imaging at different timepoints
Study NCT06478875 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: [68Ga]Ga-PentixaFor PET imaging
Description: PET imaging of adrenal glands
Study NCT06359795 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-AlF-FAPI PET/CT, 99mTc-DTPA SPECT/CT
Description: Patients underwent 18F-AlF-FAPI PET/CT and 99mTc-DTPA SPECT/CT scans within 10 days.
Study NCT04463615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leflunomide
Description: Given PO
Study NCT05139979 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breathing and Wellness Webinar
Description: Simha Kriya : a 3-minute energizing breathing practice to expand lung capacity and improve immunity, to be practiced twice daily.~Nadi Shuddhi - a gentle 4-minute breathing practice for creating mental balance and relaxation, to be practiced for a minimum of 4 minutes daily.~Isha Kriya - a 15-minute guided meditation that incorporates the breath and the awareness to create mental clarity and health, to be practiced at least once (ideally twice) daily.
Study NCT05139979 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Routine Daily Activity
Description: Participants in the control group are asked to perform routine daily activities until enrolled into the intervention arm.
Study NCT05496803 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: routine education plus digital video disk
Description: Parents receiving routine education plus digital video disk before their children receiving congenital heart disease catheterization. The DVD content was the same as the routine education but was presented audio-visually, and the video was easy to understand by the general public.
Study NCT05496803 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: routine education
Description: Parents receiving routine education before their children receiving congenital heart disease catheterization