AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06596226 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathways Parent Mediated Intervention
Description: Pathways-trained research clinicians will conduct 90-minute weekly coaching sessions with caregivers in the family's home or other convenient location. Caregivers will receive a written version of the program manual. Sessions will review information about social communication, infusing mutual gaze in social sensory routines, and using naturalistic developmental behavioral strategies. Interventionists will demonstrate intervention strategies and provide caregivers with practice feedback and self-reflection.
Study NCT06596226 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pathways Parent Mediated Intervention without Mutual Gaze
Description: Pathways-trained research clinicians will conduct 90-minute weekly coaching sessions with caregivers in the family's home or other convenient location. Caregivers will receive a written version of the program manual. Sessions will review information about social communication, social sensory routines, and naturalistic developmental behavioral strategies described in the program manual. Interventionists will demonstrate intervention strategies and provide caregivers with practice feedback and self-reflection.
Study NCT06606262 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tonsillotomy
Description: Bilateral partial removal of the palatine tonsils to a level between the pharyngeal pillars and the tonsillar capsule. Surgery will be performed under general anesthesia using monopolar electrocautery.
Study NCT06606262 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Tonsillectomy
Description: Bilateral extracapsular removal of palatine tonsils. Surgery will be performed under general anesthesia using cold knife dissection.
Study NCT06618339 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Mindfulness-based intervention
Description: 8 Session Mindfulness-based intervention
Study NCT06618339 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Mindfulness-based intervention
Description: 8 Session Mindfulness-based intervention
Study NCT06623162 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gemcitabine + cisplatine
Description: 4 cycles
Study NCT06622239 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone
Description: naltrexone 50mg for 6 weeks
Study NCT05111275 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive exercises
Description: Exercises that stimulate and train memory, attention, executive functions, language and gnosis.
Study NCT06622239 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo for 6 weeks
Study NCT06624735 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: psychometry
Description: ADHD test and measurement of IQ level
Study NCT05917522 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Abatacept
Description: Injection: 125 mg/mL of a clear to slightly opalescent, colorless to pale-yellow solution in a single-dose prefilled ClickJect autoinjector
Study NCT05917522 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care at US Transplant Centers
Description: Control group, remaining on SOC (Tacrolimus/ Mycophenolic Acid (MPA)/ Prednisone (Pred))
Study NCT05196347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: In dapagliflozin arm, subjects will be received dapagliflozin 5 mg for 4 weeks. Uptitration to 10 mg will be done between 5 to 12th weeks, if eGFR dip \<20%.
Study NCT05196347 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin
Description: In dapagliflozin arm, subjects will be received dapagliflozin 5 mg for 4 weeks. Uptitration to 10 mg will be done between 5 to 12th weeks, if eGFR dip \<20%.
Study NCT04741477 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: CBD will be topically applied
Study NCT04741477 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC
Description: THC will be topically applied
Study NCT04741477 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: a placebo product (without cannabinoids) will be topically applied
Study NCT05812118 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical active learning
Description: The intervention will last for 8-10 weeks. The ALPHYL intervention will be conducted in physical education (PE) and non-PE lessons by teachers. In addition to the PE lessons, at least three physically active activities in subjects other than PE will be conducted every day (5 days per week), with a total duration of approximately 30 minutes of light and moderate-to-vigorous physical activity per day. The weekly dose of physically active learning will thus be 100-150 minutes, so that a volume of 800-1200 minutes is foreseen during the 8-10 weeks. The PE classes will also be conducted in a mix of cooperative learning, non-linear pedagogy and health-based PE.
Study NCT05748561 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant human erythropoietin 4,000 UI and 2,000 UI
Description: Intravenous recombinant human erythropoietin (10,000 IU every 24 hours for 5 days)
Study NCT05748561 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methylprednisolone succinate 500 mg
Description: Intravenous Methylprednisolone succinate (1 g daily for 5 days)
Study NCT05312983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audiological and vestibular tests
Description: 6h of audiological and vestibular tests divide in 3 sessions :~* Session A : objective audiological tests~* Session B ; subjective audiological tests~* Session C : balance tests.
Study NCT05312983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: A 10 mL blood sample will be collected during the study.
Study NCT05312983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: neurocognitive self-questionnaire
Description: Four self-questionnaires to fill out to measure sleep quality, memory and emotional state
Study NCT06406725 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Point-of-Care Ultrasound of the Airway
Description: Patients who are recruited will have an ultrasound performed of their larynx while they are on noninvasive positive pressure ventilation and then a second ultrasound when they are removed from noninvasive positive pressure ventilation. Between the two ultrasounds, the otolaryngology team will perform their fiberoptic nasolaryngoscopy, as per standard unit protocol and patient care.
Study NCT05356481 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: segmental muscle vibration
Description: Segmental muscle vibration will delivered over the target muscles by means of vibrator with general physical therapy session
Study NCT06566365 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Subcostal Transversus Abdominis Plane Block
Description: After ensuring airway safety under general anesthesia, a bilateral Transversus Abdominis Plane Block using 20 cc of 0.25% bupivacaine with a subcostal approach under ultrasound guidance will be administered
Study NCT05977179 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary intervention to mitigate Post-Acute COVID-19 Syndrome
Description: As it was described in the arm/group descriptions.
Study NCT05977179 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Attention Control
Description: As it was described in the arm/group descriptions.
Study NCT06582771 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: Sotorasib 960 mg (8 pills) daily
Study NCT05738291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1839100
Description: BI 1839100
Study NCT05738291 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching BI 1839100
Description: Placebo matching BI 1839100
Study NCT05738291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: midazolam
Description: midazolam
Study NCT05738291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: digoxin
Description: digoxin
Study NCT05738291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rosuvastatin
Description: rosuvastatin
Study NCT05638139 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SygeLIX-F + SygeLIX-G
Description: SygeLIX-F (plug) is inserted through the internal orifice while cryptoglandular space is filled by SygeLIX-G (gel).
Study NCT05087680 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACTPrEP
Description: ACTPrEP will include a 60-minute initial session and a series of 30-minute follow-up sessions. Sessions will focus on the Thoughts, Emotions, Associations, Memories, and Sensations (TEAMS) relevant to PrEP uptake and adherence.
Study NCT05087680 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Standard of Care
Description: Enhanced Standard of Care (ESOC) will include one 30-minute PrEP education session.
Study NCT06064695 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Whole-body Electrical Muscle Stimulation Exercise
Description: This is a fitness device that delivers whole-body electrical muscle stimulation in conjunction with exercise programs using an iPad App. The stimulation suit (fitted shorts/shirt, vest, leg straps, arm straps) will be donned with the assistance of trained research personnel. Muscle groups stimulated include biceps, triceps, pectorals, abdominals, periscapular musculature, paraspinal musculature, gluteus musculature, quadriceps, and hamstrings. The stimulation level of each individual muscle group can be tailored to participant responses and tolerance (i.e. stimulation of the quadriceps and biceps can occur at different settings). While the participant is following along with the video, a qualified health care professional will be monitoring and adjusting the stimulation levels based on participant responses; rate of perceived exertion will also be monitored to ensure safe moderate intensity levels are maintained.
Study NCT03767231 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Xpert HCV Viral Load Finger-stick Point-of-Care test (Cepheid)
Description: The investigators will randomly assign eligible and consented patients to either to HCV POC VL Group or Reference Group. All participants will take a short survey regarding HCV care and treatment. As part of the investigators' ED HCV Screening and Linkage to Care Program, all participants will receive the standard-of-care clinical laboratory-based HCV RNA viral load testing via whole blood (i.e. patient will receive blood drawn). This standard-of-care HCV viral load testing result will be provided to participant when it is available (usually 1-2 days later). Participants in the HCV POC VL Group will receive the novel POC HCV RNA viral load testing and the result of the novel test will be disclosed to the patients approximately within 1 to 1½ hours of the testing.
Study NCT05227430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational video tutorials
Description: Educational video tutorials (Hysterectomy, Bilateral salpingo-oophorectomy, Bilateral salpingectomy)
Study NCT05828901 — intervention group
Intervention type: OTHER
Intervention: S1PR analysis on immune cells
Description: S1P receptor 1 and 5 expression will be measured on immune cells
Study NCT06644417 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQA3605 tablets plus NAs
Description: TQA3605 tablets is core protein regulator
Study NCT05637593 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Upper-limb movement training with the aid of RAS
Description: Three target bowls, labeled as the left, middle, and right target bowl, will be placed on the table at an equal distance from the main bowl. The distance between a target bowl and the main bowl is set at 30 cm. Wooden beads with a diameter of 2 cm will be put in target bowls. The main bowl will be placed in front of the patient.~Patients will be asked to listen to the RAS sound, use the right hand to take one bead at a time from the left target bowl to the main bowl, repeat this movement for the middle and right target bowls, and keep repeating this order. They should keep their movements consistent with the sound of the RAS, with one RAS sound corresponding to one pick-up movement.~Each daily training will consist of three rounds separated by two 5-minute breaks. Each round will consist of four consecutive sessions (for each session: 2-minute training followed by a 30-second break). The training will last for a total of 21 days.
Study NCT05637593 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Upper-limb movement training without the aid of RAS
Description: Three target bowls, labeled as the left, middle, and right target bowl, will be placed on the table at an equal distance from the main bowl. The distance between a target bowl and the main bowl is set at 30 cm. Wooden beads with a diameter of 2 cm will be put in target bowls. The main bowl will be placed in front of the patient.~Patients will be asked to use the right hand to take one bead at a time from the left target bowl to the main bowl, repeat this movement for the middle and right target bowls, and keep repeating this order. They are asked to execute the task as fast as possible.~Each daily training will consist of three rounds separated by two 5-minute breaks. Each round will consist of four consecutive sessions (for each session: 2-minute training followed by a 30-second break). The training will last for a total of 21 days.
Study NCT04967430 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Lambda-1A
Description: Peginterferon lambda is a covalent conjugate of human recombinant non-pegylated IFN lambda (IFN L) and a 20-kDa linear PEG chain.~Peginterferon lambda Injection is a sterile, nonpyrogenic, ready-to-use solution (0.4 mg/mL) that is clear to opalescent, colorless to pale yellow, and essentially free of particles. Lambda Injection is provided in a 1-mL long Type I glass syringe (0.18 mg/syringe) with a staked 29-gauge, 1/2- inch, thin-walled needle. The syringe has a rigid needle shield and is stoppered with a plunger stopper. Syringes are prefilled with a solution of Peginterferon lambda Injection, mannitol, L-histidine, polysorbate 80, hydrochloric acid, and water for injection; they are intended for a single use at adjustable doses. The syringe is marked with dose indicator lines, which are used as a reference point for administering the correct dose.
Study NCT04967430 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo will be 0.9% sodium chloride (normal saline) solution. A plastic 1 mL syringe will be prefilled by the study pharmacy. Each syringe will contain 0.5 mL (0.45 mL to match the volume of the Interferon plus 0.05 mL overfill) to allow for needle priming by the unblinded study nurse.
Study NCT06408090 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IDECIDE-HOSPICE
Description: 12-pg educational booklet detailing information about hospice including what hospice is, why someone would use hospice, who pays for hospice, and where hospice services are delivered
Study NCT06408090 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: IDECIDE-HOSPICE
Description: 12-pg educational booklet detailing information about hospice including what hospice is, why someone would use hospice, who pays for hospice, and where hospice services are delivered
Study NCT05195879 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: XTR004
Description: Single dose intravenous injection of XTR004. Serial whole-body PET scan will be obtain after injection, blood and urine collection after injection for the assessment of pharmacokinetics.
Study NCT05187195 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based telerehabilitation with exercise videos
Description: Balance, walking, strengthening, posture videos etc. taken in different positions will be uploaded to the telerehabilitation system. A personalized exercise program will be created from these exercises. This program will be defined to the account of the patient and the follow-up of the person will be carried out through the system.
Study NCT05187195 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise brochure
Description: Photos and explanations of exercises taken in different positions such as balance, walking, strengthening, posture etc. will be uploaded to the telerehabilitation system. A personalized exercise brochure will be created from these exercises. This program will be defined for the patient's account and the patient will be asked to follow the exercises with this brochure.
Study NCT06282887 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music therapy
Description: The intervention has two parts. The first part is an approximately 15-minute music therapy session to induce relaxation and positive memories attached to the relaxing live music provided by a credentialed music therapist. The second part is music listening during the scanning process.
Study NCT06644417 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: TQA3605 Placebo plus NAs
Description: Placebo without drug substance
Study NCT06627686 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Air way occlusion pressure
Description: Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients with Traumatic Brain Injury
Study NCT05061134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ceralasertib
Description: Ceralasertib (240 mg) will be administered orally twice daily.
Study NCT05061134 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Durvalumab (1500 mg) will be administered intravenously once every 28 days for participants who weight above > 30 kgs. For participants who weigh below ≤ 30 kgs, weight-based dosing equivalent to 20 mg/kg of durvalumab will be administered.
Study NCT06009926 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo urine sample collection
Study NCT06009926 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Broccoli Sprout/Broccoli Seed Extract Supplement
Description: Given PO
Study NCT06331585 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: low dose radiotherapy
Description: LDRT (5Gy/5f) of oligometastasis, oligoprogression, and oligopersistence of NSCLC after immunotherapy
Study NCT06627361 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PRO-FLEX PIVOT Foot evaluation
Description: The subject will wear the PRO-FLEX PIVOT foot for 4 weeks, following which they will complete questionnaires and undergo a Time Up and Go test
Study NCT06627361 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Class III ESAR Foot evaluation
Description: The subject will wear his usual Class III ESAR Foot foot for 4 weeks, following which they will complete questionnaires and undergo a Time Up and Go test
Study NCT04706546 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodynamic effect of exercise under Sildenafil
Description: Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise under SIldenafil.
Study NCT04706546 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Hemodynamic effect of exercise
Description: Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise.
Study NCT06009926 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Administration
Description: Given PO
Study NCT06265753 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gastrocinemius Function Massage
Description: The purpose of gastrocnemius massage is to alleviate muscle stiffness in the gastrocnemius muscle and enhance mobility in the foot and ankle of the individuals involved. During the GFM application, the patient assumes a prone posture on a suitable treatment bed. The therapist positions themselves behind the patient's side and secures the patient's foot between their hip and ilium.The therapist firmly holds the gastrocnemius muscle using both hands and applies pressure to the ankle, causing it to move in the direction of dorsiflexion. Simultaneously, the therapist applies mobilisation in the cranial direction, following the same path as the gastrocnemius muscle fibres, using both hands. Afterwards, the therapist gently pulls the arm and trunk backwards until the foot and gastrocnemius muscle become relaxed. The application is sustained in a rhythmic manner . We will apply this massage aproximately 10 min to experimental group.
Study NCT06265753 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham application
Description: The sham application was conducted when the patient was lying face down, with the hands placed on the gastrocnemius muscle without any movement. We will apply this application aproximately 10 min to experimental group.
Study NCT04763083 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVG-111
Description: Open label, continuous iv infusion, escalating doses of NVG-111 for minimum 3 cycles
Study NCT06009926 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06184581 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lithium Carbonate
Description: The trial is designed as a single-blinded two-armed, parallel randomized trial with randomization 1:1 to lamotrigine versus lithium.
Study NCT05073380 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Intervention Group - PRO-ECO Intervention
Description: The PRO-ECO intervention will be tailored to individual sites. Through collection of focus group and baseline data, the intervention will be further refined to provide site-specific adjustments, such as specific materials in the built environment design modification or targeted training. Identified features of effective interventions outlined in the literature have informed the development of the intervention foundation and potential tailoring.