AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05978401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLS-012+GLS-010+paclitaxel+carboplatin
Description: GLS-012+GLS-010 will be given via IV infusion on Day 1 of each 21-day cycle in combination with paclitaxel and carboplatin. Combination treatment will be administered 4\~6 cycles.GLS-012+GLS-010/GLS-010 may continue until disease progression or loss of clinical benefit.
Study NCT06557967 — intervention group
Intervention type: OTHER
Intervention: No drug
Description: This is a non-interventional study and no study drug will be provided.
Study NCT05447104 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mastication
Description: Chewing sugar-free gum for 20 min
Study NCT05028322 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMIQUIMOD cream
Description: Cream to apply before intra-dermal vaccine injection
Study NCT05028322 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HEPATITIS B SURFACE ANTIGEN
Description: HBV Vaccine
Study NCT05028322 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: HEPATITIS B SURFACE ANTIGEN
Description: HBV Vaccine
Study NCT04745338 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 3max cool shaping device
Description: cryolipolysis sessions are applied on abdomen area each session for 40 min. each
Study NCT04745338 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: low calolric diet
Description: low caloric diet (1200cal/day)
Study NCT04745338 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: low calolric diet
Description: low caloric diet (1200cal/day)
Study NCT06474637 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AEON Endoscopic Powered Stapler Handle and Reload
Description: The AEON™ Endoscopic Stapler places two triple-staggered rows of titanium staples while simultaneously transecting between the two triple-staggered rows of staples. The size of the staples and staple line length are based on the selection of the Stapler Reload (2.0mm, 2.5mm, 3.25mm, 4.0mm, 5.0mm and 5.5mm).
Study NCT05036317 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin (Jardiance®;
Description: Each tablet contains the active substance of 10 mg empagliflozin as well as the adjuvant lactose-monohydrate and is taken orally once daily in the morning.
Study NCT05146999 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: QM1114-DP
Description: QM1114-DP
Study NCT05447104 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mastication
Description: Chewing sugar-free gum for 20 min
Study NCT05146999 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06018376 — intervention group
Intervention type: DRUG
Intervention: Systemic oncological treatment
Description: Oncological systemic treatment for at least 3 months or being in oncological follow-up after having received systemic treatment for a minimum of 3 months
Study NCT05261126 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enclitide Chloride
Description: Enclitide Chloride administered orally
Study NCT05261126 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo matching enclitide chloride administered orally
Study NCT05156749 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: short-arm fiberglass cast
Description: fracture stabilization of salter harris I/II fractures with a fiberglass short-arm cast
Study NCT05156749 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: long-arm fiberglass cast
Description: fracture stabilization of salter harris I/II fractures with a fiberglass long-arm cast
Study NCT06495645 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AI-assisted upper gastrointestinal endoscopy
Description: AI-assisted upper gastrointestinal endoscopy
Study NCT06495645 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AI-assisted upper gastrointestinal endoscopy
Description: AI-assisted upper gastrointestinal endoscopy
Study NCT06433271 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transdiagnostic Behavior Therapy (TBT)
Description: TBT manualized treatment incorporates daily exposure exercises from up to four categories of avoidance that are most characteristic of the emotional disorders (i.e., situational, interoceptive, imaginal, and positive emotional).
Study NCT06433271 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual-Problem Solving Therapy (TAU-PST)
Description: PST is an evidence- based psychotherapy implemented in VA Primary Care - Mental Health Integration (PC-MHI), with hundreds of VA providers trained in the intervention nationally. The primary aim of PST is to improve a patient's ability to cope with stressful events by adopting an adaptive perspective to stressors and using goal-focused, problem-solving behaviors to manage the problems associated with the stressors.
Study NCT05267652 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preoxygenation with Non-Invasive Positive Pressure Ventilation
Description: The delivery of oxygen and ventilation by non-invasive mechanical ventilation via a tight-fitting mask from the initiation of preoxygenation until the initiation of laryngoscopy. Trial protocol will not dictate the brand or type of mechanical ventilator that will be used to deliver non-invasive ventilation.
Study NCT05036317 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control Intervention
Description: Placebo will be provided by Boehringer Ingelheim. It is identical to the interventional product apart from the active compound.
Study NCT06206018 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PROM_R knee rehabilitation program
Description: The rehabilitation program consists of 5 weekly sessions for 4 weeks, supervised by a specialized physiotherapist at every session.~All patients follow the same order of treatment and exercises, starting with massage and mobilization, followed by the corresponding exercise program, and ending with Neuromuscular Electrical Stimulation (NMES) and cryotherapy.
Study NCT05668286 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: A combination of 1 mL of triamcinolone acetonide (40 mg/mL) and 1 mL of prilocaine hydrochloride (2%)
Description: patients in group 1 received an anterior extra-articular steroid injection under USG guidance, patients in group 2 received posterior intra-articular steroid injection under USG guidance. A combination of 1 mL of triamcinolone acetonide (40 mg/mL) and 1 mL of prilocaine hydrochloride (2%) were injected to all patients.
Study NCT06018623 — intervention group
Intervention type: OTHER
Intervention: It is an observational study and no non-routine procedures will be performed on patients. Routine anesthesia procedure will be applied to the patients
Description: It is an observational study and no non-routine procedures will be performed on patients.~Routine anesthesia procedure will be applied to the patients
Study NCT01637155 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cholecalciferol
Description: One baseline oral dose of 50.000 UI to determine pharmacokinetics. After 28 days, patients take a period of 90 days of standardization of cholecalciferol based on baseline levels. After this period, patients receive a second oral dose of 50.000 UI to determine a second pharmacokinetics.
Study NCT05377372 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breastfeeding support group
Description: community-based breastfeeding support group aimed to increase exclusive breastfeeding success rates among Black women
Study NCT05377372 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Observation
Description: Observe prospectively for breastfeeding initiation, duration and longitudinal health of child with sickle cell disease
Study NCT04165213 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Care of Older Persons in their Environment (COPE) online module training
Description: An online module version of training for clinicians (OTs and RNs) in the evidence-based dementia caregiving program called Care of Older Persons in their Environment (COPE) is the intervention being tested for non-inferiority against the usual instructor-led COPE training. COPE modules include rich multimedia content, simulated scenarios, interactive assessments to keep the learner engaged The content is packaged into the latest the latest Shareable Content Object Reference Model (SCORM) specifications, which will allow for repurposing and sharing with other institutions. Each of the ten modules last 45-60 minutes.
Study NCT05267652 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Facemask Oxygen
Description: The delivery of supplemental oxygen via a non-rebreather mask or bag-mask device without manual ventilation from the initiation of preoxygenation until induction. Trial protocol will not dictate the brand or type of facemask. The decision between use of a non-rebreather mask and use of a bag-mask device will be made by treating clinicians. The decision of whether to provide manual ventilation with a bag-mask device between induction and laryngoscopy will be made by treating clinicians.
Study NCT05935306 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen
Description: All participants will undergo the same conventional surgical procedure. Patients will receive the FBM simulation and will be treated identically to the G2 group.
Study NCT06142032 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Metaverse support group
Description: Delivery method: Online, virtual platforms. Number of sessions: 5. Duration of each session: 1.5 hours. Sessions will adhere to evidence-based protocols for conducting support groups with a trauma-informed approach. Each session will cover a specific topic of interest related to the challenges faced by Ukrainian refugees (e.g., stress management, cultural adjustment, self-care, etc.).~Support group session structure:~* Introduction, check-in, ground rules;~* Introducing the topic (topics will be chosen based on the feedback received from a previous session; the first session will cover a topic chosen by the facilitator);~* Encouragement of participants to share thoughts, ideas and experiences;~* Psychoeducation on the topics;~* Summary, takeaway, feedback.
Study NCT06142032 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: In-Person support group
Description: Delivery method: In-Person, traditional. Number of sessions: 5. Duration of each session: 1.5 hours. Sessions will adhere to evidence-based protocols for conducting support groups with a trauma-informed approach. Each session will cover a specific topic of interest related to the challenges faced by Ukrainian refugees (e.g., stress management, cultural adjustment, self-care, etc.).~Support group session structure:~* Introduction, check-in, ground rules;~* Introducing the topic (topics will be chosen based on the feedback received from a previous session; the first session will cover a topic chosen by the facilitator);~* Encouragement of participants to share thoughts, ideas and experiences;~* Psychoeducation on the topics;~* Summary, takeaway, feedback.
Study NCT05935306 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Photobiomodulation simulation
Description: The person responsible for applying the FBM will simulate the radiation by placing the devices in the same places described for the FBM group, however, the equipment will remain turned off.
Study NCT05935306 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: . Patients will receive FBM and will be treated identically to the G2 group. The irradiated region will be on the lesion at 4 equidistant points on the vertex of a flat square 1 cm away.
Study NCT05935306 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ibuprofen simulation
Description: Placebo ibuprofen will be manipulated by pharmacy (Matias Gonzalez)
Study NCT05272631 — intervention group
Intervention type: DEVICE
Intervention: Retrograde Femoral Nail Advanced
Description: No drug will be given as part of this study. Participant will undergo surgery with RFNA based on the surgeon's decision and the site's SOC.
Study NCT05272631 — intervention group
Intervention type: DEVICE
Intervention: Tibial Nail Advanced
Description: No drug will be given as part of this study. Participant will undergo surgery with TNA based on the surgeon's decision and the site's SOC.
Study NCT05921487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time Restricted Eating
Description: Time Restricted Eating Protocol: Subjects will be instructed to limit caloric consumption to a 10-hour TRE window. The window start-time will be self-selected (individualized). During the eating window, subjects will not be restricted on types or quantities of food consumed, and will be advised to continue their usual diets. Subjects will not be required to monitor their caloric intake. During the fasting period, subjects will be encouraged to stay hydrated and drink ample water. Outside the designated eating window, subjects are only permitted to consume medication, water, or zero-calorie herbal drinks such as unsweetened tea or black coffee.
Study NCT04775537 — intervention group
Intervention type: DEVICE
Intervention: OssiMend™ Bioactive Moldable
Description: Lumbar Spine fusion with OssiMend™ Bioactive Moldable
Study NCT06114537 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide
Description: The used intervention in this study is acetazolamide, which belongs to a class of drugs known as carbonic anhydrase inhibitors and has been used with other medications to treat high ocular pressure due to certain types of glaucoma~Patients in the treatment group will receive 250 milligrams of oral acetazolamide twice daily for 16 weeks.~Patients randomized to the treatment group will switch to 125 milligrams of oral acetazolamide twice daily for another four weeks when the central foveal thickness (CFT) on OCT is reduced by ≥25% at the evaluation visit at 16 weeks after the baseline visit. These patients will continue with this dose till the end of the study when the CFT on OCT is stable or further reduced. If the CFT on OCT has increased, they switch back to 250 milligrams of oral acetazolamide twice daily for another 12 weeks.
Study NCT05274620 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: IntelliCare
Description: A mobile intervention that use principles of computerized therapy to decrease symptoms of depression
Study NCT04587362 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Musculoskeletal Ultrasound
Description: High quality ultrasound scanners and high-resolution transducers, will be used to scan 16 joints sites for each subject. Ultrasound had excellent spatial resolution, making it an highly efficient, non-invasive tool for the assessment on enthesitis, which is an early feature of psoriatic arthritis. It is an affordable and accessible tool that is widely used in rheumatology practice.
Study NCT00690911 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: adalimumab
Description: 40mg dose subcutaneously using sterile technique. The site research staff will instruct and supervise subjects or a designee or nurse on proper injection technique during site visit evaluations. Subjects or a reliable designee will administer injectable study drug at home in between site visit evaluations.
Study NCT05721898 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cortical Bone Mechanics Technology
Description: Cortical Bone Mechanics Technology (CBMT). CBMT testing will be performed bilaterally, and flexural rigidity (EI) will be calculated. If a participant has fractured a wrist or forearm bone in the prior 1-year, then only the arm that was not fractured will be tested. During testing, participants will lie supine in the CBMT instrument.
Study NCT04917601 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evira Care treatment
Description: The intervention aim to examine the effectiveness of using a digital support system (Evira) in treatment of childhood obesity. Through daily weighings at home using a special designed scale, which sends data directly to an application on the parents phone and to a clinic homepage, the child's weight development can be easily monitored. Participants can be randomized to either the intervention group or the control group. The control group will receive local standard treatment.
Study NCT04753216 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Given IV
Study NCT04753216 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan Sucrosofate
Description: Given IV
Study NCT04917601 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Lifestyle Care
Description: The control group will receive the local standard care of treatment addressing lifestyles for childhood obesity without any restriction in visits or clinical support. This is the current standard care of treatment for childhood obesity.
Study NCT05239065 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: The basic intervention
Description: The participants will receive a paper-printed booklet introducing stress and stress management strategies, regular exercise, deep breathing and mediation, etc, as well as a HUAWEI portable device at the recruitment. During the following 3-month intervention phase, there is not informational materials, portable device data feedback, online group discussion or interpersonal communications with the participants. The participants will only need to fill in a simplified questionnaire biweekly.
Study NCT05239065 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The personalized interventions
Description: The participants will receive a paper-printed booklet introducing stress and stress management strategies and a HUAWEI portable device at the recruitment. A neurologist will be the health educator to host an online group for free communications. The typical stress-relieving methods and the strategies of using portable device will be explained by providing small videos, online article links and nursing coaching in person. The health educator will give regular knowledge educations about the stress hazards, stress management necessities and skills on weekly basis. The weekly data of HUAWEI portable devices will be sent to the participants along with personalized suggestions by trained nurses. At certain occasions, gifts and rewards will be sent out for encouragement and keeping attachment to the program. The participants will be required to fill in the weekly questionnaires online for feedback.
Study NCT03827889 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: WMP of fluoride varnish
Description: Application of fluoride varnish (drug of the intervention - Duraphat, Colgate) on all teeth, regardless of the lesions found
Study NCT03827889 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TWLP of fluoride varnish
Description: application of the fluoride varnish (drug of the intervention - Duraphat, Colgate) only on the teeth with active initial caries lesions detected through visual examination after prophylaxis
Study NCT04515901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 2% lidocaine
Description: Viscous lidocaine
Study NCT04515901 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Methylcellulose and cherry flavouring
Study NCT05836883 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ExoFlo
Description: Local injection of bone marrow mesenchymal stem cell derived extracellular vesicles
Study NCT05836883 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Local injection of normal saline
Description: Placebo
Study NCT06463132 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PEP/Euflexxa
Description: Euflexxa (PMA: P010029)
Study NCT06463132 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PEP
Description: PEP (Purified Exosome Product)
Study NCT04979585 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: 200mg ,IV,d1,Q3W.
Study NCT04979585 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib
Description: 8mg,oral, d1-14,Q3W.
Study NCT04979585 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nab-Paclitaxel
Description: 260mg/m2,IV,d1,Q3W.
Study NCT04865796 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactoferrin products
Description: Patiens will use a toothpaste and 2 tablets per day (between foods) for home oral care.
Study NCT04865796 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Probiotics products
Description: Patiens will use a toothpaste and a chewing-gum (for 10 minutes a day) for home oral care.
Study NCT04865796 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard home oral care
Description: Patiens will use a normal toothpaste for home oral care.
Study NCT04594096 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth visits
Description: Receiving telehealth visits with a medical provider (MD or NP) 2-3 days after last chemotherapy administration in the cycle
Study NCT04594096 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Receiving care as usual from the UC Davis Comprehensive Cancer Center
Study NCT05481996 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App-Based Pain Education and Exercise
Description: Telerehabilitation is defined as providing techniques for therapeutic rehabilitation remotely or off-site using telecommunication technologies. Thus, our intervention will be based on the use of a smartphone application created especially for the study that will contain a program of progressive physical exercises with images and descriptions, educational messages and an online booklet for the study subjects, totaling 8 weeks of training and pain education.
Study NCT05481996 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Online booklet
Description: An online booklet containing information about chronic low back pain and weekly messages about low back pain causes, suggestions for lifestyle modifications and behavior will be delivered, as well as an incentive to perform physical exercises.