AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06584812 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Ticagrelor
Description: Period 4: Ticagrelor; loading dose of Ticagrelor followed by daily maintenance dose until Day 8.
Study NCT06005948 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: The dynamic neuromuscular stabilization group will receive developmental postures based on developmental kinesiology. It will involve a supine 3month Position, side-lying Position, Quadruped, oblique sitting, bear position, squat Position. Each position will be performed for 30-60 s for five reps, active exercise 5-10 reps under supervision for two days/week, and unsupervised for 3 days/week for 8 weeks
Study NCT06005948 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: No intervention will be made.
Study NCT05889013 — intervention group
Intervention type: DEVICE
Intervention: Nasal Nitric Oxide testing
Description: Collection of already performed clinical data and nNO testing
Study NCT06089954 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: eHealth education intervention (web or chatbot)
Description: The intervention involves pre-disclosure education via an eHealth intervention (web or chatbot). The intervention will review the types of actionable results being returned, the method of return, the differences between research and clinical testing, the need for confirmation testing and the benefits, risks and limitations of receiving actionable genetic research results and study steps and procedures.
Study NCT04818814 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation App
Description: Listening to audio-guided meditation sessions using a mobile app.
Study NCT04818814 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Engagement and Distraction App
Description: Listening to engaging and distracting videos of interest to the participant using a mobile app.
Study NCT06089954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: eHealth education intervention (web or chatbot)
Description: The intervention involves pre-disclosure education via an eHealth intervention (web or chatbot). The intervention will review the types of actionable results being returned, the method of return, the differences between research and clinical testing, the need for confirmation testing and the benefits, risks and limitations of receiving actionable genetic research results and study steps and procedures.
Study NCT06060002 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group A - Stent exchange if cholecystectomy dated beyond 3 months
Description: Stent removal and cholangiogram and stone clearance (if recurrent stone/s is/are found). Stent exchange if cholecystectomy dated beyond 3 months
Study NCT06060002 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Group B - Diagnostic EUS/MRCP/USG abdomen and LFT at 3 months
Description: Diagnostic EUS/MRCP/USG abdomen and LFT at 3 months to see recurrence of CDL. ERC and stone clearance (if recurrent stone/s found on EUS/MRCP/USG abdomen)
Study NCT05273242 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artesunate Injection
Description: * Artesunate: 2.4 mg/kg/dose at 0 hours, 12 hours, and 24 hours and thereafter every 24 hours; IV injection; duration of treatment 7 days. This is the standard dose recommended for the treatment of severe malaria.~* Infliximab: 5 mg/kg/dose (once only), single IV infusion over 2 hours. This is the standard dose that is given repeatedly for the treatment of psoriasis.~* Imatinib: 400 mg/dose; orally once daily; duration of treatment 14 days. This is the standard maintenance dose which is at the lower end of that used for several years in the treatment of hematological malignancies.
Study NCT05523570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNC364
Description: 2 subjects (both male and female) to receive 20 mg HNC364 intramuscular administration to evaluate the safety and tolerability of HNC364 injectable suspension. Then 8 subjects are planned for enrollment in each cohort (the ratio of male to female is as close as possible) to receive 20 mg HNC364 intramuscular administration. The proposed dose levels for use were determined to be appropriate based on the collective nonclinical data (pharmacology and toxicology) for HNC364 and the nonclinical and clinical data of the marketed drug rasagiline.
Study NCT05523570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNC364
Description: 8 subjects are planned for enrollment in each cohort (the ratio of male to female is as close as possible) to receive 40 mg HNC364 intramuscular administration. The proposed dose levels for use were determined to be appropriate based on the collective nonclinical data (pharmacology and toxicology) for HNC364 and the nonclinical and clinical data of the marketed drug rasagiline.
Study NCT05523570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNC364
Description: 8 subjects are planned for enrollment in each cohort (the ratio of male to female is as close as possible) to receive 60 mg HNC364 intramuscular administration. The proposed dose levels for use were determined to be appropriate based on the collective nonclinical data (pharmacology and toxicology) for HNC364 and the nonclinical and clinical data of the marketed drug rasagiline.
Study NCT06677411 — intervention group
Intervention type: OTHER
Intervention: Observention of vitamin D
Description: It is an observational study
Study NCT06676605 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Withania somnifera
Description: The experimental supplement administered to patients in this study was Withania somnifera, commonly known as ashwagandha. It is classified as a dietary supplement and is regulated similarly to pharmaceutical medications. The supplement has been authorized for commercialization and use by the Food and Drug Administration (FDA). Participants received the supplement in the form of 500 mg capsules, taken daily over a 40-day period, following the manufacturer's instructions. The range of the recommended daily dose is between 240 and 600 mg. The purpose of administering this supplement was to evaluate its impact on various health parameters, including serum lipid concentrations and body composition, in the study's participants.
Study NCT06676605 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Intervention
Description: The product administered to the placebo group was designed to simulate the appearance and administration of the experimental supplement but without containing any active ingredients. Participants in the placebo group received capsules/tablets filled with starch rice. These capsules were taken daily over the same 40-day period as the experimental group, ensuring that the placebo group followed identical administration and monitoring procedures. The use of starch rice capsules aimed to serve as a neutral control, allowing for a comparison between the effects of the actual Withania somnifera supplement and the placebo.
Study NCT05570994 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 177Lu HTK03170
Description: Subjects will receive 177Lu HTK03170 treatment over 5 cycles, each cycle occurs every 8 weeks.
Study NCT05570994 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-HTK03149
Description: 68Ga-HTK03149 PET/CT imaging; intravenous during screening
Study NCT05085132 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MindFi app: Standard content
Description: Digital wellness training in this study will be delivered via the MindFi app, designed by Jaedye Labs. Content includes learning, assesesment, and practice tracks A core component of the exercises in this app is mindfulness training; however, the app also incorporates other exercises drawn from positive psychology such as journaling and diaphragmatic breathing. The app goes beyond traditional guided meditation through content that reinforces the principles and attitudes taught during in-person training, and also seeks to maximize user experience by using interactive tasks and progress charts.
Study NCT05085132 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Mindfi app: Standard content without practice
Description: In this condition, participants will receive a version of the MindFi app that does NOT contain the practice tracks, only the learning and assessment tracks.
Study NCT04462575 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Onlay bone block covered using collagen membrane
Description: The ratio is 40% of xenogenic bone particles (low resorption rate) to 60% of autogenous bone particles (contains viable cells) to be placed in recipient decorticated site and covered by onlay bone block..
Study NCT04462575 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Onlay bone block without collagen membrane
Description: Onlay bone block without collagen membrane
Study NCT05523570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNC364
Description: 8 subjects are planned for enrollment in each cohort (the ratio of male to female is as close as possible) to receive 80 mg HNC364 intramuscular administration. The proposed dose levels for use were determined to be appropriate based on the collective nonclinical data (pharmacology and toxicology) for HNC364 and the nonclinical and clinical data of the marketed drug rasagiline.
Study NCT04541901 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: 12 minutes of effleurage and petrissage on the upper limbs
Study NCT04541901 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold water immersion
Description: 12 minutes of cold water immersion at the shoulder level with water temperature between 11 to 15°C
Study NCT05601466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QN-023a
Description: NK cell therapy
Study NCT05429892 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking cessation counseling and food delivery
Description: The community health workers will delivery five 30-minute sessions during intervention months 1 through 5 to provide interpersonal level support for smoking cessation. The community health workers will conduct real-time video motivational counseling to clients. The community health workers will implement the 5As (Ask, Advise, Assess, Assist, Arrange) and support smokers in quitting, if ready, and build confidence toward quitting if they are uncertain about change.~Smokers enrolled in the TRTsocialmot1 arm will be provided with monthly delivery of food boxes in accordance with the number of persons in the household and caloric intake needed to support one week's worth of family meals. Healthy meal preparation instructions will be included and delivery by project staff will reduce transportation barriers to food access rural counties.~Participants will receive educational materials.
Study NCT05429892 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Smoking cessation counseling
Description: The community health workers will delivery five 30-minute sessions during intervention months 1 through 5 to provide interpersonal level support for smoking cessation. The community health workers will conduct real-time video motivational counseling to clients. The community health workers will implement the 5As (Ask, Advise, Assess, Assist, Arrange) and support smokers in quitting, if ready, and build confidence toward quitting if they are uncertain about change.~Participants will receive educational materials.
Study NCT06066086 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: A hinge flap will be performed to reinforce the buccal advancement flap to close the oroantral fistula at the most posterior area of the maxilla
Description: The hinge flap is raised via circular incision around the oral side of the oroantral fistula then sutured with purse suture to close the sinus membrane perforation and it is used as an additional layer that reinforce the buccal advancement flap
Study NCT06066086 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: An anteriorly based palatal flap will be performed to close the oroantral fistula at the most posterior area of the maxilla
Description: Two paralleling incisions will be performed on the palatal side of the fistula. The distance between the two incisions will be 2 to 3 mm greater than the width of the fistula. Then the two incisions will be connected together via a circular incision at the bony end of the hard palate. The flap reflection will be performed, and the greater palatine vessels will be legated and cauterized to allow lateral repositioning of the flap over the fistula. The flap will be sutured to the buccal tissues.
Study NCT05601466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamid
Description: Lympho-conditioning Agent
Study NCT05601466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Lympho-conditioning Agent
Study NCT05601466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Lympho-conditioning Agent
Study NCT04808505 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cipaglucosidase alfa
Description: Sterile lyophilized powder intravenous (IV) infusion
Study NCT04808505 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Miglustat
Description: 65 mg oral capsules
Study NCT04977856 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral activation (BA)
Description: The main goal of the BA is to increase engagement in values-based activities and decrease avoidant behaviors that serve to maintain depression. The adolescent will learn about depression, how behavioral activations works, monitor their own activities, plan and do more values-based activities and deal with obstacles to getting in touch with positive reinforcement, such as avoidance behaviors.
Study NCT04977856 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Regular care within primary or secondary mental health care for children
Description: Regular care (supportive therapy, waitlist, psychological treatments, drugs, or a combination of different interventions)
Study NCT06630338 — intervention group
Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study NCT05571436 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iCan Diabetes Self-management and Prevention Support Group
Description: Participants will be asked to attend six weekly sessions and complete pre-and post-assessments with an optional focus group.~The intervention will cover the following topics: 1) Yes, iCan! - Affirmations and Empowerment, 2) The Language of Diabetes - Diabetes Synopsis, 3) Diabetes and Me - Management Strategies, 4) Extraordinary Health - Dream Team, 5) Food for Thought - Food Conscious, and 6) Discussion - Stories/Goals.~Each session is composed of a Check-in, Affirmation/Empowerment Activity, Short Presentation, Q\&A and Discussion, Goal setting, and Testing Healthy Snacks.
Study NCT05355116 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Physiolab S1
Description: A cryocompression device capable of circulating ice-water through a cuff at 6-12℃ with either a static pressure of 25mmHg or dynamic pressure of 25-50 mmHg or 25-75mmHg. The lowest temperature setting, and highest pressure setting will be used for this study.
Study NCT05355116 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Breg Vpulse
Description: A cryocompression device capable of circulating ice-water through a cuff at no lower than 5.5℃ with a dynamic peak pressure of 50 mmHg. The temperature of the ice-water, and the applied pressure, is not modifiable by the user.
Study NCT05355116 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aircast Cryo/Cuff
Description: A cryocompression device capable of circulating ice-water through a cuff at an undefined, non-modifiable temperature with a static pressure that is also undefined and non-modifiable. The device will be applied as per the manufacturer's instructions, which will represent its maximum capability.
Study NCT05355116 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GameReady
Description: A cryocompression device capable of circulating ice-water through a cuff at 1-12℃ with a dynamic pressure of 5-15 mmHg, 5-50 mmHg, or 5-75 mmHg. The lowest temperature setting, and highest pressure setting will be used for this study.
Study NCT05355116 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Physiolab Gel Therapy Wrap
Description: A cryocompression cuff that applies an undefined, non-modifiable temperature with a static pressure that is also undefined and non-modifiable. The device will be applied as per the manufacturer's instructions, which will represent its maximum capability.
Study NCT03720990 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cholic Acid
Description: Participants will be treated with cholic acid for 8 weeks
Study NCT06377800 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: navicular mobilization along conventional therapy.
Description: In the prone position, when the foot is stabilized by a towel underneath, navicular mobilization is administered. The therapist's fixing hand wraps the calcaneus, grasps the talus bone, and fixes it.~By placing the thumb on the plantar surface of the foot and pushing with the thumb of the other hand in a dorsal direction, navicular mobilization is provided.~This dorsal glide will be given with 2 sets of 5 minutes. Each session will be of 30 minutes.
Study NCT06377800 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: conventional therapy
Description: ultrasound therapy at 1.5 w/cm2 for 7 minutes in continuous mode at a 3MHz frequency. Stretching targets the medial arch and surrounding muscles like calf and tibialis posterior with exercises such as arch lift, heel raise, towel pickup, and toe lift. Additionally, strengthening exercises for intrinsic foot muscles like standing toe curls and towel toe curls are included. Ice pack application for 10 minutes follows
Study NCT05935904 — intervention group
Intervention type: OTHER
Intervention: Exposure
Description: Dietary habits:~Data collected using food frequency questionnaire~Risk factors associated with metabolic syndrome:~Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome progression during pregnancy~Pregnancy outcomes:~Adverse pregnancy and birth outcomes.
Study NCT05935904 — intervention group
Intervention type: OTHER
Intervention: Non exposure
Description: Dietary habits:~Data collected using food frequency questionnaire~Risk factors associated with metabolic syndrome:~Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome progression during pregnancy~Pregnancy outcomes:~Adverse pregnancy and birth outcomes.
Study NCT05429892 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Food delivery
Description: Smokers enrolled in the TRTsocial2 arm will be provided with monthly delivery of food boxes in accordance with the number of persons in the household and caloric intake needed to support one week's worth of family meals. Healthy meal preparation instructions will be included and delivery by project staff will reduce transportation barriers to food access rural counties.~Participants will receive educational materials.
Study NCT06258161 — intervention group
Intervention type: PROCEDURE
Intervention: Spinal Fusion
Description: Realignment and fusion of adult spinal deformity
Study NCT06258161 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention for control group.
Study NCT04715230 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IXT-m200
Description: IXT-m200 binds METH with high selectivity and affinity. The product contains a murine METH-binding variable region and the constant domains of a human immunoglobulin G (IgG) 2κ. This antibody isotype was chosen because of the lower risk of immune response compared to an IgG1 or IgG3. IXT-m200 targets METH, does not rely on binding to any endogenous target for its action, and has been well-tolerated in previous clinical studies.
Study NCT04715230 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lorazepam
Description: Lorazepam is a benzodiazepine that is safe and commonly used to treat agitation and dysphoria in the emergency setting.
Study NCT04715230 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Haloperidol
Description: Haloperidol is commonly used to treat agitation due to psychosis.
Study NCT05870644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cycling exercise in room temperature at 25 degree Celsius.
Description: The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 25 degree Celsius.
Study NCT05870644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cycling exercise in room temperature at 34 degree Celsius.
Description: The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 34 degree Celsius.
Study NCT06438406 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Orthotic devices and therapeutic exercise (Group A)
Description: Group A consisting of patients who were prescribed orthoses, to use gradually, and a 20-session rehabilitation programme, based on the Back School method
Study NCT04786977 — intervention group
Intervention type: OTHER
Intervention: No Intervention, Observational Study
Description: No Intervention
Study NCT06438406 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Orthotic devices (Group B)
Description: Group B consisting of patients who were only prescribed orthoses for the lower limbs
Study NCT05722106 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Persuasive Appeal
Description: Persuasive appeals were manipulated using promotional flyers ostensibly distributed by the Public Health Agency of Canada.
Study NCT04776993 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methimazole
Description: Methimazole for 72 weeks
Study NCT04776993 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radioiodine or thyroidectomy
Description: Treatment with radioiodine or with thyroidectomy
Study NCT04601467 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD5718
Description: Oral dose of AZD5718 (tablet) once daily for 12 months