AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05414357 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Functional Magnetic Resonance Imaging at rest and in activation with attentional task
Description: Participants complete 3 successive assessments (T1: baseline, T2: at 6 months, T3: after galvanic vestibular stimulation). Assessments include:~* Functional and Anatomic Magnetic Resonance Imaging at rest and in activation (only at T1 and T2).~* Biological and physiological measurements~* Spatial memory task~* Cognitive battery~* Questionnaires (sleep, quality of life)
Study NCT04903743 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: bupivacaine
Description: group B received 28ml of 0.25% bupivacaine and 2ml normal saline
Study NCT04903743 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine
Description: group B received 28ml of 0.25% bupivacaine and 2ml normal saline
Study NCT04903743 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: magnesium sulfate
Description: group BM received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.
Study NCT05397782 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BioNourish, a component of Flourish HEC
Description: BioNourish, one of three parts of the Flourish HEC system, is a vaginal moisturizing gel - a Class II medical device with FDA 510k clearance obtained in 2020.
Study NCT04832100 — intervention group
Intervention type: DRUG
Intervention: Pregabalin 150mg, imipramine 25mg
Description: Conventional treatment for fibromyalgia was given to patients. Clinical follow-ups with questionnaires and interview were arranged then.
Study NCT05370703 — intervention group
Intervention type: BEHAVIORAL
Intervention: My A:care
Description: Mobile application with Motivational messages
Study NCT05370703 — intervention group
Intervention type: BEHAVIORAL
Intervention: Smart Coach
Description: Mobile application with Motivational messages
Study NCT04672382 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: During the 1st session, each of the middle forearms of the subject will be divided into two squared areas (4x4 cm) located 3 cm apart. Two areas will be treated with an intradermal injection of morphine (0.05 ml, 0.1 mg/ml), and two areas with an intradermal injection of isotonic saline.
Study NCT03972891 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: intervention break of 12 weeks
Description: The intervention of this study is a break of the intervention for 12 weeks under the following conditions:~* no therapeutic intervention during the break~* no language-specific specific exercises~* language-specific strategies in everyday life can be applied, e.g. modeling techniques
Study NCT05536388 — intervention group
Intervention type: OTHER
Intervention: Biological Sample Collection
Description: Skin biopsy (2-3mm) and/or blood (up to 50 mL); saliva; excess/leftover biospecimens that were (or will be) collected for other purposes (e.g., medical procedure)
Study NCT06434987 — intervention group
Intervention type: PROCEDURE
Intervention: Retrograde Inferior Vena Cava Perfusion
Description: Retrograde inferior vena cava (RIVP) involves perfusing oxygenated blood into the inferior vena cava, which then flows towards the viscera, abdominal organs and lower extremities. By maintaining perfusion to these regions during cardiopulmonary bypass (CPB) and induced hypothermia, Retrograde inferior vena cava (RIVP) helps mitigate the risk of ischemic injury to the abdominal organs. Following the initiation of total cardiopulmonary bypass, the body temperature will be gradually lowered to achieve deep-moderate hypothermia ( 24-38°C). This procedure will involve the combination of selective antegrade cerebral perfusion and retrograde inferior vena cava perfusion. Antegrade perfusion will be maintained at a flow rate of 5-7mL/min/kg, while retrograde perfusion will be regulated to sustain the required pumm pressure and blood flow.
Study NCT06434987 — intervention group
Intervention type: PROCEDURE
Intervention: Antegrade cerebral perfusion
Description: After mild to moderate hypothermia is achieved, a cannula will be inserted into the right axillary artery, brachiocephalic or innominate artery to provide continuous flow to the brain. A flow rate of 5-7mL/min/kg will be maintained.
Study NCT04646564 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard of care
Description: patients receive appropriate therapy at the discretion of the treating oncologist, i.e. systemic therapy according to molecular subtypes, including chemotherapy, endocrine therapy, targeted therapy, or immunotherapy.
Study NCT04760145 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multicomponent Exercise with Blood Flow Restriction
Description: * 10 minutes of initial warm-up.~* 20 minutes of strength exercises.~* 10 minutes of resistance exercises.~* 10 minutes of coordination and balance exercises.~* 5 minutes of flexibility.~* 5 minutes of return to calm and relaxation.~All of this multicomponent training will be performed with blood flow restriction.
Study NCT04646564 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard of care
Description: patients receive appropriate therapy at the discretion of the treating oncologist, i.e. systemic therapy according to molecular subtypes, including chemotherapy, endocrine therapy, targeted therapy, or immunotherapy.
Study NCT04646564 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: radiotherapy + standard of care
Description: Patients receive radiotherapy to all known metastases. SBRT technique is preferred, especially for metastases in bone, lung and liver. Conventional RT can be used when SBRT is not appropriate, such as metastasis in mediastinal or contralateral supraclavicular nodal regions. Total doses of 30Gy to 50Gy in 5 fractions for SBRT are recommended depending on the tolerance of adjacent normal tissue. Total dose of 60Gy in 25 fractions is recommended for conventional RT.~Patients can receive systemic therapy concurrently with RT at the discretion of treating radiation oncologist. After completion of SBRT to all sites of known metastatic disease, patients will continue standard of care therapy per the treating oncologist.
Study NCT04455932 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Abbreviated non-contrast MRI of the liver
Description: every 6 months
Study NCT04455932 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound surveillance
Description: every 6 months
Study NCT04455932 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Multiphase contrast-enhanced liver MRI
Description: screening
Study NCT04760145 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Multicomponent Exercise without Blood Flow Restriction
Description: * 10 minutes of initial warm-up.~* 20 minutes of strength exercises.~* 10 minutes of resistance exercises.~* 10 minutes of coordination and balance exercises.~* 5 minutes of flexibility.~* 5 minutes of return to calm and relaxation.~All of this multicomponent training will be performed without blood flow restriction.
Study NCT06198725 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Trimtab
Description: High fiber group will take Trimtab (a kind of multi bran and high fiber grain compound powder) 60g per day to intake 28g dietary fiber for 12 weeks.
Study NCT05654077 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-T Cell Injection
Description: intravenously once, and the dose group was 3.0 × 10\^6cells/kg、9.0 × 10\^6cells/kg、1.5 × 10\^7cells/kg。
Study NCT05654077 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Fludarabine 25\~30mg/m2/d was infused intravenously for 3 consecutive days. (- 5 days to - 3 days)
Study NCT05654077 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclophosphamide
Description: 250\~350mg/m2/d cyclophosphamide was infused intravenously for 3 consecutive days. (- 5 days to - 3 days)
Study NCT05074108 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pilot study
Description: Aiming for an interaction 6 week course that will discuss many aspects of health and wellness.
Study NCT05667077 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amantadine
Description: The amantadine group is treated with amantadine capsules 100mg twice a day for two weeks
Study NCT04671732 — intervention group
Intervention type: PROCEDURE
Intervention: Fenestrated endovascular aortic aneurysm repair
Description: Fenestrated endovascular aortic aneurysm repair consists in excluding a juxtrenal or suprarenal aneurysm by deploying a covered stent (stent graft) in the aorta so as to created sealing zones on both sides of the aneurysm. Since the proximal sealing is located in the visceral segment of the aorta, fenestrations are created to maintain blod flow in renal and visceral arteries. These fenestrations are custom made for each patient. Brindging covered stents are deployed between each fenestration and corresponding target arteries in order to insure sealing of the system.
Study NCT04671732 — intervention group
Intervention type: PROCEDURE
Intervention: open repair of abdominal aortic aneurysm.
Description: Open repair of abdominal aortic aneurysms consists in cross-clamping the aorta on both sides of the aneurysm and replace the diseased segment by a prosthetic graft.
Study NCT04866745 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetotherapy plus exercise
Description: The VARIMAG-4E magnetotherapy device will be used. It is a pulsed radiofrequency energy device. The device has a voltage of 220V, 4 amps of intensity, 50 Hz of frequency and a maximum power of 100 Gauss. For the active treatment application, the patient will be in supine position and will introduce both knees in the 50 cm coil in case of bilateral knee osteoarthritis. In the case of unilateral knee osteoarthritis, the affected knee will be introduced in the 30cm coil. The duration of the treatment will be 20 minutes, the frequency administered will be 50 Hz and a power of 100 Gauss.
Study NCT04866745 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Microwave plus exercise
Description: The application of deep heating therapy will be with the patient in a sitting position. The VARITRON 250-EP microwave device will be used with a frequency of 2450 MHz and a maximum output power of 250W. In the case of unilateral knee osteoarthritis, the circular applicator with a diameter of 170mm will be placed approximately 15 cm from the knee. The duration of the session will be 20 minutes, 10 minutes over the internal face and 10 minutes over the external face of the knee. In the case of bilateral knee osteoarthritis, the large lumbar applicator will be placed approximately 15 cm from the anterosuperior face of both knees for 20 minutes. The patient will have to perceive a moderate heat sensation.
Study NCT04866745 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Magnetotherapy plus exercise
Description: The protocol and device will be the same in the active/placebo treatment. The sham device does not emit an electromagnetic field. The energy from the active device is not felt by the user, and the active device cannot be distinguished in any way from the placebo device.
Study NCT06206096 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxaliplatin+capecitabine+bevacizumab+PD-1 antibody
Description: oxaliplatin will be administered once every 3 weeks at a dose of 130 mg/m2; Capecitabine will be taken orally at a dose of 1g/m2 twice daily for continuous oral administration over 14 days; Bevacizumab will be administered intravenously every 3 weeks at a dose of 7.5 mg/kg; PD-1 antibody was given due to different types.
Study NCT05027386 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apatinib, Irinotecan, Temozolomide
Description: The enrolled patients diagnosed with recurrent or refractory pediatric neuroblastoma received apatinib combined with IT regimen chemotherapy, the treatment including combination therapy phase and monotherapy maintenance phase.
Study NCT05676918 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive Psychology Intervention
Description: PPI includes 2 modules: hedonic well-being and eudaimonic well-being.
Study NCT05676918 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavior Therapy
Description: CBT includes 3 modules: behavioral activation, cognitive restructuring, and interpersonal skills.
Study NCT05330026 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Diaphragm´s study during yoga breathing
Description: Study and compare the activation of the diaphragm during different breaths: rest, ujjayi and pursed lips
Study NCT05330026 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Diaphragm´s study during yoga breathing
Description: Study and compare the activation of the diaphragm during different breaths: rest, ujjayi and pursed lips
Study NCT05589792 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: Placebo before sleep for 3 nights before the study (inclusive)
Study NCT05589792 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetazolamide
Description: Acetazolamide 250 mg 3 nights before the study at bedtime, Acetazolamide 500 mg for 2 nights before the study (inclusive) at bedtime.
Study NCT05874206 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cratos™ Stent Graft
Description: Cratos™ Stent Graft TEVAR procedure for the treatment of aortic lesions.
Study NCT05977907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab is an investigational drug in this study
Study NCT05977907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IO102-103
Description: IO102-103 is an investigational drug in this study.
Study NCT05299983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MyMenoPlan
Description: Participants are asked to spend at least 20 minutes on the website (MyMenoPlan) assigned to them.
Study NCT05299983 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants are asked to spend at least 20 minutes on at least one of the following websites:~1. North American Menopause Society: https://www.menopause.org/for-women~2. National Institute on Aging: https://www.nia.nih.gov/health/topics/menopause~3. The Office on Women's Health-Menopause: https://www.womenshealth.gov/menopause
Study NCT05056428 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 8-week mindfulness program
Description: The .b Foundations course is an 8-week mindfulness program developed by Mindfulness in Schools Project (MiSP) for school teachers and personnel. It includes a taster session and 8 weekly sessions. Each session lasts for 1.5 hours with a specific theme (e.g. Lesson 1 waking up from autopilot). Formal and informal mindfulness practices (e.g. mindful eating, body scan, mindful walking, habit releaser etc.), psychoeducation, cognitive exercises, inquiry, and home practice are involved.
Study NCT04549402 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mirror Therapy group
Description: The intervention protocol will be carried out under the same environmental conditions and, as far as possible, on time. The intervention will last 4 weeks, with a periodicity of 7 weekly sessions. In total there will be 28 sessions lasting between 15 and 45 minutes depending on the number of joints affected.
Study NCT04549402 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Video group
Description: The intervention protocol will be carried out under the same environmental conditions and, as far as possible, on time. The intervention will last 4 weeks, with a periodicity of 7 weekly sessions. In total there will be 28 sessions lasting between 15 and 45 minutes depending on the number of joints affected.
Study NCT06253416 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: a home exercise program consist of stretching and strengthening exercises , 5 repetitions of each exercise three days a week for 12 weeks
Study NCT06253416 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: exercise freely and without supervision with their daily routine
Study NCT05315609 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR Meditation
Description: This 4-week VR program will use the Oculus Pro-Quest 2 headsets for the 15-minute seated VR meditation twice per week for a total of 8 sessions over the 4 weeks.
Study NCT05198713 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: New hearing aid
Description: Participants will complete testing while using a novel hearing aid which has been fit to compensate for their hearing loss.
Study NCT05623891 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 177Lu-B5-IgG4
Description: 177Lu-B5-IgG4 injection followed by SPECT scan
Study NCT05285501 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Group general fitness training
Description: A single session of general fitness training will be composed of low-intensity, general-fitness exercises. Most of the exercises will be carried out in a sitting position and standing positon. The session will contain aerobic (general warm-up), musculo-articular (strengthening muscles and joints range of motion) and stabilizing exercises (improve spatio-visual coordination). Conducted by a physiotherapist in group form.
Study NCT05285501 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group general fitness training
Description: A single session of general fitness training will be composed of low-intensity, general-fitness exercises. Most of the exercises will be carried out in a sitting position and standing positon. The session will contain aerobic (general warm-up), musculo-articular (strengthening muscles and joints range of motion) and stabilizing exercises (improve spatio-visual coordination). Conducted by a physiotherapist in group form.
Study NCT05285501 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Group relaxation and psychoeduaction
Description: A single session of relaxation (10 minutes) psychoeducation (10 minutes) will contain minilectures about mental well-being and psychohygiene. In summary 20 minutes.
Study NCT05285501 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VRTierOne
Description: As a virtual reality source, VRTierOne device (Stolgraf®) were used. Thanks to using head mounted display and the phenomenon of total immersion VRTierOne Stolgraf® provides an intense visual, auditory and kinesthetic stimulation. It can have a calming and mood-improving effect or help the patients recognize their psychological resources and motivate to the rehabilitation process. In the virtual therapeutic garden there are a rich set of symbols and metaphors based on Ericksonian Psychotherapy approach. The most important is the Garden of Revival which symbolizes the patient's health. It used to be full of life and energy, now it is neglected, requires work to be revived. In the therapeutic process day by day, the lector (therapist) tells the patient a symbolic story about his/her situation. By performing tasks in the virtual garden, the patient influences the course of this story, becomes an active participant of the therapeutic process and sees the effects his work.
Study NCT06438679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tofacitinib 5 MG
Description: Tofacitinib 5mg BID+thalidomide 50mg BID+tacrolimus 0.1mg/kg QD per oral
Study NCT05697133 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SEMSTOP
Description: This program has been developed based on Story Theory and will be implemented individually online. The session content, units and topics in the program are arranged according to the conceptual content and flow of the theory. The program has been created in a certain flow, based on the concepts of purposeful dialogue, connecting with itself and facilitating the theory.
Study NCT05697133 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: control grup
Study NCT03712826 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-TNF Drug
Description: Crohn patient with antiTNF treatment
Study NCT03712826 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ustekinumab
Description: Crohn disease with ustekinumab treatment
Study NCT04993625 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: avoid axillary sentinel lymph node biopsy after neoadjuvant chemotherapy
Description: Selective Omission of Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy In HER-2 positive/Triple Negative Breast Cancer Patients with Excellent Radiologic Response to the Breast and Axilla
Study NCT04887571 — intervention group
Intervention type: OTHER
Intervention: No Intervention - Observational Registry
Description: All consecutive adult patients in the Cape Metropole and the Garden Route Health District with an Acute coronary syndrome (STEMI, NSTEMI, Unstable Angina) will be recruited into the PERFUSION Registry.
Study NCT04886271 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HX009
Description: Eligible participants will receive HX009 treatment at 5mg/Kg via IV infusion over 60-120 minutes, and the scheduled dosing cycle is once every 2 weeks.
Study NCT05357456 — intervention group
Intervention type: BEHAVIORAL
Intervention: Cognitive function assessment; functional magnetic resonance imaging
Description: cognitive function measurement
Study NCT05357456 — intervention group
Intervention type: PROCEDURE
Intervention: laparoscopic adrenal surgery
Description: Only a subgroup of the autonomous cortisol secretion patients will have the laparoscopic adrenal surgery
Study NCT06202573 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: rhinoplasty
Description: patients who have a step counter and we do not motivate them to walk
Study NCT04942886 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Entecavir
Description: The intervention group take entecavir 0.5mg everyday by oral administration for 3 years after hematopoietic stem cell transplantation.