AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06463938 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental group
Description: Lasotronix will be applied following its protocol
Study NCT06463938 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: Combination of laser and paste
Description: This group will receive the combination of above two treatments
Study NCT06463938 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control group
Description: this will be a control group
Study NCT04977427 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dextenza 0.4Mg Ophthalmic Insert
Description: Dexamethasone inserted into lower punctum at the end of cataract surgery in order to control inflammation in the eye for the following 30 days after surgery.
Study NCT04977427 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone Acetate 1% Oph Susp
Description: Standard Prednisolone taper following cataract surgery, QID for one week, followed by TID for one week, BID for one week, and QDaily for one week, then stop.
Study NCT06357728 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous glucose monitoring
Description: Continuous glucose monitoring sensor: All study participants wear the sensor on the back of either right or left upper arm for up to 10 days. Glucose levels will be recorded from the interstitial fluid every 5 minutes using intermittent/ flash glucose scanning. Data will be captured using a receiver.
Study NCT06009458 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Description: Acuity 200™ Orthokeratology Contact Lenses are intended to be worn overnight with removal during following day. The lenses are designed to produce a temporary reduction of myopia by reversibly altering the curvature of the cornea. The lenses are manufactured from fluoroxyfocon A, which is a gas permeable contact lens material composed of a siloxanyl fluoromethacrylate copolymer. The material name fluoroxyfocon A is registered with United States Adopted Name (USAN).The Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens is available in spherical, asymmetrical, aspheric, and tangential lens designs to best fit the individual cornea, using corneal topography and/or diagnostic lenses.
Study NCT06635902 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-citrulline
Description: Intravenous L-citrulline (50 mg/kg + 9mg/kg/hr.) for 16 hours
Study NCT06635902 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Isotonic normal saline
Study NCT06635902 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-citrulline
Description: Intravenous L-citrulline (25 mg/kg + 9mg/kg/hr.) for 16 hours
Study NCT06636214 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CHATO-I
Description: Online communication education program
Study NCT05687656 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: InnovaMatrix AC porcine placental ECM therapy
Description: All eligible subjects will be treated with a weekly application of sterilized, porcine placental ECM followed by standard of care moist wound therapy and offloading
Study NCT05321810 — intervention group
Intervention type: DRUG
Intervention: Apixaban
Description: This is observational study and the patients in the apixaban cohort include those who are exposed to apixaban in the real world settings.
Study NCT05321810 — intervention group
Intervention type: DRUG
Intervention: Warfarin
Description: This is observational study and the patients in the warfarin cohort include those who are exposed to warfarin in the real world settings.
Study NCT05127603 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral intervention
Description: Individually tailored physiotherapy that fits within the guideline non-specific neck pain (KNGF, 2016) with a focus on influencing dysfunctional illness perceptions and dysfunctional movement/ pain behavior, by means of communication, body awareness exercises, functional movements and exposure techniques. Tools are supplied to create an appropriate explanatory model for the pain, for functional movement behavior and active coping in a patient's daily lives.
Study NCT06541392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: breakfast 6.30 am
Description: This group will have breakfast time from 6.30 to 7.30 am
Study NCT06541392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: breakfast 7.31 am
Description: This group will have breakfast time from 7.31 to 8.31 am
Study NCT05425108 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Binocular CP1
Description: Binocular active projection of defocused image in the peripheral visual field
Study NCT06171997 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Swaddling after bath group
Description: The babies were bathed in the bathtub. Then swaddling was done. The baby was taken into the incubator and waited for 15 minutes. At the end of 15 minutes, the swaddle was opened quietly and slowly, without disturbing the body posture. Stress and comfort scores were given by two observers by video recording the babies before bathing, before swaddling and after swaddling.~Newborns' stress will be assessed with the Newborn Stress Scale and their comfort with the Newborn Comfort Behavior Scale.
Study NCT06267261 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KOLMI® surgical face mask (OP-Air)
Description: 12 subjects are exposed to birch pollen allergen in ALYATEC EEC while wearing a KOLMI® surgical face mask (OP-Air)
Study NCT06481826 — intervention group
Intervention type: DRUG
Intervention: Glofitamab
Description: Glofitamab given in standard dosage
Study NCT06527976 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: dexmedetomedine added to bupivacaine for adductor canal block
Study NCT06527976 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: dexamethasone added to bupivacaine for adductor canal block
Study NCT05077306 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: music therapy group
Description: individual bedside single session of receptive music therapy (RMT) by a certified Music therapist- GIM fellow in presence. STAI Y-1 was administered 5 min. before session (STAI Y-1 PRE) and 15 min. after session (STAI Y-1 POST) in paper form. HR and O2Sat were recorded from the bedside monitor 3 times: start session (T0), 10 min. (T1), end session (T2).Participants i were asked to fill in an optional open-ended question concerning their experience with music therapy.
Study NCT05295602 — intervention group
Intervention type: RADIATION
Intervention: CT scan
Description: CT of lower leg
Study NCT04976140 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PN-101
Description: PN-101: Mitochondria isolated from Allogeneic Umbilical Cord-derived Mesenchymal Stem Cells.~3 or 6 subjects are enrolled in each dose group in line with the traditional 3+3 rule-based method, and the investigator intravenously administers a single-dose of the investigational product according to the planned dose.
Study NCT06635746 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vinpocetine
Description: Increasing doses of vinpocetine to assess tolerability.
Study NCT06636097 — intervention group
Intervention type: DEVICE
Intervention: Full arch
Description: design
Study NCT06095817 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet Delivered Brief Intervention (IDBI)
Description: The intervention is an online module that can be accessed through smartphone, tablet, computer or other device. Participants will receive information about alcohol expectancies, alcohol use and norms, identity (service member, veteran, civilian), sleep, stress, and strategies for coping on the job.
Study NCT06530485 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Microbiota-directed food
Description: MDF can modulate the gut microbiota and enhance host immunity, growth, and development in malnourished children. Each sachet of MDF (100 gm) provides approximately 500 kcal.
Study NCT06530485 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Khichuri
Description: Khichuri is a home-based nutritious food with high energy and protein. This arm also contains zinc (10 gm/day), micronutrient powder, and an egg daily.
Study NCT05482672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fisetin
Description: Fisetin is a plant flavanol senolytic found in strawberries, persimmons, and cucumbers. This naturally derived senolytic has few side effects and previous animal models of both osteoarthritis and rheumatoid arthritis have demonstrated that the senolytic supplement fisetin reduces inflammation and slows cartilage breakdown.
Study NCT05482672 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GetHealthy-OA mind-body program
Description: The GetHealthy-OA mind-body program emphasizes increased physical activity, healthy diet and sleep habits to lessen osteoarthritis and depressive symptoms
Study NCT05482672 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral capsule
Description: The oral placebo will consist of corn starch and gelatin capsules
Study NCT05482672 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Health education booklet
Description: The booklet will containing brief summarized information that reflects the active intervention topics including the trajectory of pain and recovery for those with knee osteoarthritis, the role of relaxation strategies to manage pain, and the importance of returning to engagement in activities of daily living
Study NCT06382779 — intervention group
Intervention type: PROCEDURE
Intervention: reverse shoulder arthroplasty
Description: resection of proximal humeral tumors and reconstruction with reverse shoulder arthroplasty
Study NCT05848271 — intervention group
Intervention type: OTHER
Intervention: Patient Registry
Description: Participants who have been diagnosed with HPDL mutations will be enrolled to patient registry.
Study NCT05848271 — intervention group
Intervention type: OTHER
Intervention: Dry blood spots sampling
Description: Dry blood splots require 500nl of blood.
Study NCT04601064 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Collaborative Care Model
Description: Collaborative care (CC) is an evidence-based model of integrated mental health and substance use disorder care endorsed by the American Psychiatric Association for the integration of mental health and substance use disorder care into primary care settings. CC includes the following components: 1) A collaborative care team of multidisciplinary health care providers consisting of the primary physician, a care manager and a consulting psychiatrist, providing care in a coordinated fashion; 2) A population focus with the team working together to provide care and continuously measure and track health outcomes of a defined population of patients; 3) A measurement-guided approach with systematic use of disease specific patient reported outcome measures, such as symptom rating scales like the PHQ-9 to drive clinical decision making; and 4) Evidence-based practices with the team adapting scientifically proven treatments within an individual clinical context to achieve improved health outcomes.
Study NCT05209490 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Femoral nerve blockade under ultrasound control with a peripheral nerve stimulator
Description: Following the ultrasound visualization of the femoral nerve, a insulated injection needle was connected to the nerve stimulator . Under ultrasound visualization guidance, the needle of the electronic nerve stimulator was positioned at the sciatic nerve (in plane) from its lateral side at a slightly superior position . A marker for LA introduction was the visualization of the needle end near the nerve, and a positive muscular response . Subsequently, the introduction of LA solution was initiated.If LA was spreading from the lateral side down to the nerve, then the needle was replaced to the upper point of the nerve and the rest of LA was introduced, and vice versa . The presence of a complete and incomplete spread of LA along the entire circumference of the nerve was assessed. Correspondingly, if the anesthetic was spreading upwardly, the needle would be downwardly replaced.~In addition, a sciatic femoral nerve block is performed.
Study NCT05209490 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: femoral nerve blockade under ultrasound control without a peripheral nerve stimulator
Description: Under ultrasound visualization guidance, the needle owas positioned at the femoral nerve (in plane) from its lateral side at a slightly superior position . A marker for LA introduction was the visualization of the needle end near the nerve. Subsequently, the introduction of LA solution was initiated. The position of the needle was corrected 1-2 times according to the type of anesthetic spread. If LA was spreading from the lateral side down to the nerve, then the needle was replaced to the upper point of the nerve and the rest of LA was introduced, and vice versa . The presence of a complete and incomplete spread of LA along the entire circumference of the nerve was assessed. Correspondingly, if the anesthetic was spreading upwardly, the needle would be downwardly replaced.~In addition, a sciatic nerve block is performed.
Study NCT04916171 — intervention group
Intervention type: OTHER
Intervention: incidence
Description: It is aimed to determine the incidence of endometriosis and/or adenomyosis in patients diagnosed with polycystic ovary syndrome, or to determine the incidence of polycystic ovary syndrome in patients diagnosed with endometriosis and/or adenomyosis.
Study NCT04846556 — intervention group
Intervention type: OTHER
Intervention: data collection
Description: data collection : gender, weight, biological data (platelets, hemoglobin, creatinine, liver function tests), performance status, type of Venous Thromboembolic Event (VTE) and cancer, anticancer and anticoagulant therapy, adverse events (bleeding, recurrence of Venous Thromboembolic Event (VTE), death) up to 6 months after their Venous Thromboembolic Event (VTE).
Study NCT04928911 — intervention group
Intervention type: BIOLOGICAL
Intervention: COVID-19 vaccine
Description: Adults about to receive a COVID-19 vaccine fill out a questionnaire of potential predictors of side effect occurrence
Study NCT06503042 — intervention group
Intervention type: DRUG
Intervention: Chemotherapy combined with immunotherapy
Description: Patients in the chemotherapy combined with immunotherapy group use any chemotherapy drug in combination with any immunotherapy drug. The premise is that the treatment regimen for patients is consistent with the diagnostic and treatment protocols.
Study NCT06503042 — intervention group
Intervention type: DRUG
Intervention: Chemotherapy only
Description: Patients in the chemotherapy alone group use any chemotherapy drug. The premise is that the treatment regimen for patients is consistent with the diagnostic and treatment protocols.
Study NCT06178679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ST-100 (vezocolmitide)
Description: ST-100 (vezocolmitide) Ophthalmic Solution 60 μg/ml
Study NCT06178679 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Vehicle Ophthalmic Solution
Study NCT06143293 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters
Description: Duty cycle: At Visit 1, while the frequencies are being changed over Period 1, 2, and 3, duty cycle will be held constant at the participant's randomly assigned first duty cycle setting. At Visit 2, duty cycle will be held constant at the participant's randomly assigned second duty cycle setting. At Visit 2 the participant will receive whichever duty cycle they were not randomly assigned at Visit 1. Therefore, by completing the combination of three frequencies at two duty cycles, each participant will have received all six possible VNS parameter combinations over the two study visits. Chronic period: The VNS setting for the Chronic Period in between Visit 1 and Visit 2 will be the same settings as tested during Visit 1 Period 3. Since Visit 1 Period 3 settings were already randomly assigned to each participant, another randomization for the chronic period is not needed.
Study NCT05085600 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Patients will begin performing the cervical stabilization exercise, and will taught to perform the contraction of deep neck flexor muscle activity with the help of the Stabilizer Pressure Biofeedback Unit (Chattanooga, USA) in supine.~In addition, progress will continued in the exercise of the contraction of deep neck flexor muscles in other positions.~The progression of the exercises will be adapted to each patient, depending on their evolution. Firstly, exercises will undertaken in the supine and standing positions; once these positions will mastered, the exercises progressed to asymmetric positions with cervical bending and/or rotation toward each patient's most symptomatic side.
Study NCT05085600 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Therapy + Exercise
Description: 20-minute session. In the first 5 minutes, muscle techniques will be performed to prepare the tissue of the upper cervical spine before applying joint techniques. In the next 15 minutes, manipulation and / or mobilization techniques of the upper cervical spine, including the C2-3 segment, will be combined with cervical exercise
Study NCT05212272 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PET-MRI Brain Scan
Description: Before starting radiation, participants will have a PET scan and MRI scan of the brain. After 2 to 3 weeks of radiation treatments, participants will have a repeat PET scan. Then 1 month after radiation participants will have another PET scan
Study NCT05212272 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood draw
Description: Blood draws will be taken at baseline, one month after radiation treatment and 3 to 4 months after radiation treatment.
Study NCT05212272 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory testing
Description: 3 sessions with simple tests to evaluate how the brain is working. These tests primarily check things like memory, attention, and thought process. The whole set of tests will take 1 hour each time.
Study NCT05212272 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Optional lumbar puncture for cerebrospinal fluid collection
Description: Participants that consent for cerebrospinal fluid collection will have 6 and 20 ml of cerebrospinal collected at baseline.
Study NCT05533359 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Text-Messaging (TM)
Description: Participants in the TM condition will receive HIPAA-compliant bidirectional text messages. These texts will include a brief message alerting patients that they are eligible to receive a test kit and asking participants if they would like to receive a test kit. Participants who reply yes will receive an additional message with information about how to receive a test kit.
Study NCT05533359 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conversational Agent (CA)
Description: Patients in the CA condition will receive a link to an automated, scripted and interactive conversational agent used to mimic human interaction to: 1) elicit specific hesitancy factors and barriers to testing; 2) provide tailored information to address each individual's hesitancy factors and barriers to testing; and 3) offer access to at-home rapid test kits.
Study NCT05533359 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Patient Navigation (PN)
Description: Participants in the PN condition will receive a call from a Community Health Worker to assist with the process of receiving a COVID test. At this time the participant has the option to opt-out of this follow up phone call. The patient navigation from the Community Health Worker includes practical advice in addressing barriers to testing such as logistics, as well as fear, skepticism, and hesitancy.~There are two distinct different types of patient navigation. A person can be randomly assigned to either type, or no PN, or a combination of the two types.
Study NCT06326268 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Phototherapy system CareMin650TM
Description: * As part of preventive treatment: Photobiomodulation sessions will be carried out at a dose of 3 joules for 1 minute 51 seconds, 3 times a week (for a maximum duration of 4 to 6 weeks).~* As part of curative treatment (i.e. for patients developing mucositis, from grade I): photobiomodulation will be carried out at a curative dose of 6 joules daily (for a maximum duration of 4 to 6 weeks ) for 3 minutes 34 seconds.
Study NCT05206136 — intervention group
Intervention type: DEVICE
Intervention: Ultrasonography
Description: Neck and Low back muscles will be evaluated by ultrasound.
Study NCT05535517 — intervention group
Intervention type: OTHER
Intervention: CeraVe SA Smoothing Cleanser
Description: The CeraVe Salicylic Acid (SA) Smoothing Cleanser is formulated with salicylic acid to help exfoliate the skin and remove dirt and dead skin cells on the skin without compromising or striping moisture from the skin's natural barrier, leaving the skin feeling clean, smooth and hydrated. This salicylic acid cleanser is also formulated to include hyaluronic acid to hydrate and retain moisture and 3 essential ceramides to moisturise and help support the skin's barrier.
Study NCT06032208 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Theranova Dialyzer
Description: The Theranova dialyzer will be used for each of the hemodialysis treatments beginning week 5 and ending at the end of dialysis week 28. This will allow us to compare patient reported symptoms in weeks 1-4 on their usual dialyzer with with their symptoms on the Theranova dialyzer.
Study NCT04964050 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capozide
Description: Capozide will be administered as per the treatment sequence.
Study NCT04964050 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACE-Hemmer-Ratiopharm
Description: ACE-Hemmer-Ratiopharm will be administered as per the treatment sequence.