AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06367205 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goal-Directed Fluid Therapy (GDFT)
Description: Norepinephrine will be administered intravenously at a rate of 0.06 µg/kg/min, followed by the implementation of fluid therapy guided by SVV until reaching our target. In instances where SVV ≤ 13%, indicative of adequate effective circulating blood volume, the fluid infusion rate will be adjusted to 1 ml/kg/h. Conversely, if SVV > 13%, denoting inadequate effective circulating blood volume, a rapid infusion of 1 ml/kg of crystalloid fluid will be administered over 2 minutes, with subsequent observation of fluid reactivity after a further 2-minute interval. This process is reiterated until SVV ≤ 13% is attained. Should SVV > 13% recurs during surgery, the aforementioned intervention is repeated.
Study NCT06367205 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Regular Fluid Therapy
Description: Anesthesiologists will rely on their clinical expertise and intraoperative circulatory hemodynamic assessment to regulate fluid infusion rates and administer medications as necessary
Study NCT05251051 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: pediatric physical therapy
Description: Pediatric physical therapists will provide weekly home therapy using standard of care/best evidence procedures
Study NCT05251051 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Care Coordination
Description: A navigator will be assigned who will assist families in obtaining Early Intervention services and other therapy services if needed
Study NCT05251051 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care Coordination
Description: A navigator will be assigned who will assist families in obtaining Early Intervention services and other therapy services if needed
Study NCT04919265 — intervention group
Intervention type: OTHER
Intervention: No intervention - mother-infant cohort study
Description: There are no interventions because it is a mother-infant cohort study
Study NCT05872022 — intervention group
Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study, therefore no intervention is used.
Study NCT05011760 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Baseline [C-11]NPA PET Scan
Description: Radiotracer
Study NCT05011760 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: d-amphetamine
Description: Oral, 0.5 mg/Kg
Study NCT05011760 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Post-amphetamine [C-11]NPA PET Scan
Description: Radiotracer
Study NCT06043739 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Filgotinib
Description: Commercially developed film-coated tablet administered orally
Study NCT06043739 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Filgotinib
Description: Film-coated mini-tablets administered orally
Study NCT05368662 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality of life and sleep questionnaire
Description: Evaluation of quality of life and quality of sleep by questionnaires
Study NCT06109870 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PRECEDE-PROCEED
Description: delivered self-sampling (CHWSS) to increase screening participation.
Study NCT06646185 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Tampons
Description: Participants adopt tampons to manage their menstruation during 2 menstrual cycles. For each menstrual cycle, participants will provide vaginal microbiome samples via self-sampled swabs at 3 points.
Study NCT05460819 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture treatment
Description: Acupoint selection: Hegu-Yinxi acupoint group (clearing heat and relieving sweat), Sanyinjiao-Fuliu acupoint group (nourishing yin and tonifying kidney), Tianshu-uteri acupoint group (special effect points) (12 acupoints on both sides).~Frequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.~Operation: Use a one-time sterile acupuncture needle (0.30×40mm, Huatuo brand), insert the needle 0.5 inch along the anatomical position, level up and relieve the qi, and keep the needle for 20 minutes.
Study NCT05460819 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Acupuncture treatment
Description: Selecting acupoints: Select the side opening positions of the 6 acupuncture points in the real acupuncture group, and select non-meridian and non-points (points with less nerve distribution, sparseness, and rich muscles).~Frequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.~Operation: ① Shallow needling scheme: use a disposable sterile acupuncture needle, insert the needle 0.2 inch, without twisting, and keep the needle for 20 minutes. ②Non-invasive acupuncture plan: choose a special comfort needle with no needle tip at the top of the needle, paste a disposable sterile foam pad on the non-acupoint, and use a disposable sterile flat head The acupuncture needles were pierced into the foam pad, lightly touching but not piercing the skin, and not breathing; the needles were kept for 20 minutes.
Study NCT06258499 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: BHA
Description: BHA active ingredients include a blood-derived component and beta-tricalcium phosphate. It is manually placed into the joint fusion space during fusion surgery.
Study NCT06491147 — intervention group
Intervention type: OTHER
Intervention: Emergency front of neck access
Description: The algorithm in the DAS manual will be explained. Following this, the researcher will demonstrate the scalpel spark plug technique with a 4-step approach that is frequently used in skill teaching.~In step 1 of this approach, the technique will be demonstrated without any verbal explanation.~In the 2nd step, the technique will be demonstrated with verbal expression. In the 3rd step, the participant will be asked to have the trainer do it. In the 4th and last step, the participant will apply eFONA from start to finish.
Study NCT05542537 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brighter Bites (BB) Produce Distribution
Description: For 16 weeks in the school year, teachers in participating program schools will receive distributions of 8-10 different types of produce items.
Study NCT05542537 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brighter Bites (BB) Nutrition Education
Description: Brighter Bites Nutrition Education will consist of recipes, food preparation and storage ideas, and tips and tools to budget and plan meals. Teachers will be trained in a nutrition education curriculum, which will be implemented in the program schools as part of the BB program.
Study NCT05542537 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Create Healthy Futures (CHF) Weekly Wellness Groups
Description: Peer-facilitators will lead virtual weekly group discussions. Penn State Better Kid Care will train the wellness facilitators.
Study NCT05542537 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Create Healthy Futures (CHF) Web-Based Module
Description: Create Healthy Futures Web-Based Module is self-paced and focuses on the following topics: 1) Introduction, 2) Challenges of the food environment, 3) Nutrition and your health, 4) Food culture reform, and 5) Providers' role in creating healthy futures. The Create Healthy Futures module utilizes several educational methods to increase interactivity and engagement, including video footage of content experts, reflection activities, downloadable handouts, and action planning. Each chapter takes approximately 30-40 minutes to complete. The program is delivered on the Better Kid Care On Demand platform, an asynchronous learning management system that provides professional development training for teachers in all 50 states and 69 countries.
Study NCT06647277 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: Fecal Microbiota Transplant
Description: Fecal Microbiota Transplant
Study NCT05472272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Formula diet
Description: Participants will receive a low-calorie (815-835 kcal/day; approximately 43% carbohydrate, 29% protein, and 29% fat) formula diet product for 12 weeks, followed by a gradual food reintroduction phase combined with physical activity support for 12 weeks.
Study NCT05472272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Food-based diet
Description: Participants will receive a low-calorie (815-835 kcal/day; 45-50% carbohydrate, 20-30% protein, and 20-30% fat) food-based diet created by dietitians for 12 weeks. After 12 weeks, participants will increase energy intake gradually and be encouraged to increase daily physical activity to maintain weight loss for another 12 weeks.
Study NCT05542537 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Create Healthy Futures (CHF) Web-Based Module
Description: Create Healthy Futures Web-Based Module is self-paced and focuses on the following topics: 1) Introduction, 2) Challenges of the food environment, 3) Nutrition and your health, 4) Food culture reform, and 5) Providers' role in creating healthy futures. The Create Healthy Futures module utilizes several educational methods to increase interactivity and engagement, including video footage of content experts, reflection activities, downloadable handouts, and action planning. Each chapter takes approximately 30-40 minutes to complete. The program is delivered on the Better Kid Care On Demand platform, an asynchronous learning management system that provides professional development training for teachers in all 50 states and 69 countries.
Study NCT06209879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYSTANE™ Hydration Lubricant Eye Drops
Description: SYSTANE™ Hydration Lubricant Eye Drops (Hyaluronic Acid \[HA\] 0.15%; Polyethylene Glycol 400 0.4%; Propylene Glycol 0.3%)1-2 drops 4 times a day) and 0.1% FML (1-2 drops 3 times a day) in both eyes for 12 week
Study NCT05809752 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Dendritic Cell Vaccine
Description: Intrathecal (IT) dendritic cell vaccine (DCV) will be administered once every week. As per standard procedures of IT chemotherapy or antibody administration it is administered over 5 -10 minutes or at 1 ml/minute while monitoring the patient under sterile conditions. In general, to assure delivery of the DCVs into the ventricular space and compensate for dead space in the Ommaya, the delivery of IT DCV cells is followed by the administration of 2.5 mls of saline. In general there is a maximum volume of 10 mls of DCVs.
Study NCT06224816 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Custom 3D mask (3DM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received 3D mask during 4 hour, then crossed over to traditional mask.
Study NCT06224816 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Custom 3D mask (3DM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received 3D mask during 4 hour, then crossed over to traditional mask.
Study NCT05240716 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FES program
Description: 8 weeks intervention. 3 sessions per week. Previous to the intervention, volunteers will familiarize with the electrical stimulation by receiving three trials of the stimuli. Electrical current intensity will be set for each volunteers, with the capacity of generating a muscle contraction without inducing discomfort in the volunteer. During the FES program, patient in standing position will perform a step, while electrical current stimulation will be applied to the skin over the tibial nerve on the contralateral of the stimulation side. The FES will be delivered during the paretic plantarflexor activation according to the gait cycle. The FES session will consist of 5-minutes stimulation blocks with breaks between blocks (total session time: 30 minutes). For safety reasons, a physical therapist will supervise all the FES intervention sessions.
Study NCT04975516 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Given chemotherapy
Study NCT04975516 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: Given chemotherapy
Study NCT06224816 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Traditional mask (TM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received traditional mask during 4 hours, then crossed over to 3D mask.
Study NCT06224816 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional mask (TM) application in neonate
Description: Premature infants with a birth weight less than 1500 g r first received traditional mask during 4 hours, then crossed over to 3D mask.
Study NCT04252625 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Q-Urol
Description: Q-Urol is an over-the-counter herbal supplement manufactured by Farr Laboratories. It is a combination product composed of quercetin, pollen extract, bromelain, and papain.
Study NCT04252625 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo capsule
Study NCT04975516 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiation Therapy
Description: Undergo SBRT
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT
Study NCT05652920 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ori-C101
Description: Hepatic arterial infusion
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood collection
Study NCT04975516 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood collection
Study NCT04975516 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04975516 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06219746 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSMA-imaging
Description: Subjects undergo additional imaging i.e. PSMA/SPECT/CT and PSMA/PET/CT
Study NCT06308380 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Specific protocol of rehabilitation exercise
Description: Specific protocol of rehabilitation exercise
Study NCT06308380 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Specific protocol of rehabilitation exercise
Description: Specific protocol of rehabilitation exercise
Study NCT06308380 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short gastrocnemius surgery.
Description: During surgery, a partial release of the gastrocnemius muscle tendon is performed to relieve tension and allow greater range of motion. This procedure is typically performed on an outpatient basis and under local or regional anesthesia, which allows for a quicker recovery compared to more invasive surgeries.
Study NCT05703100 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Incremental exercise test
Description: Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W)
Study NCT05703100 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Incremental exercise test under hyperthermia
Description: Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W) performed at a room temperature of 35-38ºC (degrees Celsius).
Study NCT05703100 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Incremental exercise test under glycogen depletion
Description: Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W) under glycogen depletion by performing an exercise protocol to deplete glycogen stores plus a low-carbohydrate diet 24 h before incremental testing
Study NCT05632146 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Continuous suturing
Description: In continuous closure, each bite will be taken 2 cm from the cut edge of linea alba and successive bites taken 1 cm from each other in continuous fashion followed by gentle approximation of the wound
Study NCT05632146 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Interrupted X suturing
Description: In interrupted X closure, large bite will be taken outside-in, 2 cm from the cut edge of linea alba and the needle emerged on the other side from inside out diagonally 2 cm from the edge and 4 cm below the first bite and this strand will be crossed and continued outside-in, diagonally at 90 degree to the first diagonal. The two ends will be tied just tight enough to approximate the edges of linea alba.
Study NCT06580262 — intervention group
Intervention type: OTHER
Intervention: Routine care
Description: The investigator takes care of the patient according to the protocol in force in his department and decides on the final orientation of the patient (transfer to intensive care unit/ICU, hospitalization or home discharge).~No recommendations or instructions are given to the investigators. Each investigator is free to decide on his care and the terms of transfer, hospitalization and discharge.
Study NCT05028725 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EsophaCap Sponge
Description: Non-invasive strategy to sample esophageal tissue
Study NCT05028725 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Chromoendoscopy
Description: Lugol's iodine chromoendoscopy is a technique that is used to identify mucosal abnormalities of the esophagus
Study NCT05028725 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EsoCAN assay
Description: Biomarker Test
Study NCT04347551 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High velocity/low amplitude cervical spine manipulation
Description: The participants will receive a single cervical spine rotary manipulation to the previously identified palpable cervical segmental fixation. During the performance of the manipulation, the supine participant will rest their arms at the sides of their body. Next, the index finger of the chiropractor's contact hand will be placed on the lamina of the restricted cervical segment. The chiropractor will then rotate the participant's head contralaterally until the barrier of the cervical segments volitional end range is reached. The chiropractor's other hand will be placed behind the participant's head to induce gentle neck rotation contralateral to the chiropractor's thrusting hand. The chiropractor will deliver a manual thrust, with the thrust vector directed towards the participant's opposite eye.
Study NCT04347551 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: High velocity/low amplitude cervical spine manipulation
Description: The participants will receive a single cervical spine rotary manipulation to the previously identified palpable cervical segmental fixation. During the performance of the manipulation, the supine participant will rest their arms at the sides of their body. Next, the index finger of the chiropractor's contact hand will be placed on the lamina of the restricted cervical segment. The chiropractor will then rotate the participant's head contralaterally until the barrier of the cervical segments volitional end range is reached. The chiropractor's other hand will be placed behind the participant's head to induce gentle neck rotation contralateral to the chiropractor's thrusting hand. The chiropractor will deliver a manual thrust, with the thrust vector directed towards the participant's opposite eye.
Study NCT05333250 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Modafinil
Description: Modafinil
Study NCT05333250 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05728177 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Inhalation Aromatherapy
Description: Aromatherapy is safe, well prepared mixture used in the study that prepared by professor of pharmacology, faculty of pharmacy by mixing lavender essential oil and lavender hydrolate~Patients' medical charts in the outpatient clinic were reviewed to identify those who meet the inclusion criteria. Patients who meet the predetermined inclusion criteria were recruited in the study using simple randomization technique using computer-generated sequence technique to pick up these patients. After simple sampling and dividing patients into two groups of study and control. Patients from the study and control groups were interviewed individually by the researcher to apply the study tools as a pretest. Aromatherapy intervention was carried out for patients in the study group while those in the control group were left without any intervention to undergo the usual outpatient routine care.