AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06343207 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percussive massage gun therapy
Description: Between pre and post-test, there was a one and half minute period during which each participant were in a prone position on a medical examination bed. The experimental PT groups received a 30-second triceps surae massage on each limb, while the control group maintained the same prone position without massage. The massage gun was set to 2100bpm and 1 bar of surface pressure was indicated by the device. The massage gun movement was performed according to the manufactu'er's instructions.
Study NCT05876572 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: intradermal naloxone
Description: One time 8 mg/0.1 mL dose of naloxone to be administered intradermally
Study NCT05876572 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: microneedle injection
Description: Intradermal delivery of naloxone using microneedle
Study NCT06469658 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The standard practice dietary supplements intervention
Description: Participants receive supplements prescriptions from a physician based on current standard practices, which include biochemical markers, genetic data, and metabolic profiles.
Study NCT06469658 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The AI-guided practice dietary supplements group
Description: Participants receive DS prescriptions determined by GenAIS, an AI system which considers genetic data, metabolic profiles, biochemical markers, and patient history.
Study NCT04778761 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home ACP Video
Description: A video focused on Advance Care Planning and Hospice for patients with serious illness
Study NCT06387238 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSMA PET/CT
Description: pre-therapeutic PSMA PET/CT and post-therapeutic PSMA PET/CT after three-month novel endocrine therapy.
Study NCT06050512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ixazomib
Description: Ixazomib, a second-generation proteasome inhibitor, is used primarily in the treatment of multiple myeloma. This activity outlines the mechanism of action, indications, and contraindications for ixazomib as a valuable agent for treating multiple myeloma.
Study NCT06050512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Corticosteroids, such as dexamethasone and prednisone, are an important part of the treatment of multiple myeloma. They can be used alone or combined with other drugs as a part of treatment. Corticosteroids are also used to help decrease the nausea and vomiting that chemo might cause.
Study NCT05522114 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TMJ injection using patient specific guide
Description: Prefabricated patient specific guide used to guide the needle into the superior joint space of TMJ while real time MSCT evaluate the accuracy of needle position. Sodium hyaloronate injected within the superior joint space.
Study NCT04880057 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance+Aerobic training
Description: The RT focuses on lower extremity workout, including leg press, hamstring curls, and calf raises. The participants start with intensity at 12 RM and finished with intensity at 8 RM after 3 weeks. There are 8 repetitions, 2 sets for each action. It will take 15 minutes to complete RT.~The AeT is composed by cycling on stationary bikes in the first week, stepping on steppers in 2nd week, and running on treadmills in the last week. Participants are asked to wear a portable heart rate monitor throughout the experiments. They have to maintain their heart rates in 60%-75% of predicted maximal heart rate (moderate intensity exercise), which has been shown to be benefit on cognition\[3\]. It took the participants 25 minutes to complete AeT.
Study NCT04880057 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Agility training
Description: AT program consists of three parts: technical drills, pattern running and reactive agility training. There will be nine sessions over 3 weeks and progress the intensity, complexity or velocity every week.
Study NCT05940246 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: MI was introduced by William Miller in 1983 as a strategy to promote behavioral changes that would make people drink less. It is well established that MI can be successfully applied to many areas across the medical disciplines. Although the aim of MI is behavioral changes toward a specific goal it is necessary to understand the essence of MI with the four key interrelated elements of the spirits of MI. These are partnership, acceptance, compassion, and evocation. Together they form an equal and respectful collaboration between the MI practitioner and the patient wherein empathy and acknowledgment are important pillars. Moreover, an important message derived from the spirit of MI is the belief that patients in themselves have and know what is needed and get support from the MI practitioner to find it.
Study NCT06535646 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home exercise program using Physitrack exercise program and a smart watch
Description: Participants wear a smart watch to monitor activity levels while using a web based exercise program to follow along for 8 weeks.
Study NCT05509894 — intervention group
Intervention type: DRUG
Intervention: Ngenla
Description: As provided in real world practice
Study NCT06311227 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration
Study NCT06311227 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy
Study NCT06311227 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT scan
Study NCT04735185 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Autologous stem cells
Description: In this intervention participants will receive a 2 mL intradiscal injection into each affected disc of autologous bone marrow-derived mesenchymal stem cells from bone marrow aspirate of the posterior ilium.
Study NCT04735185 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Corticosteroid
Description: In this intervention participants will receive a 1 mL intradiscal injection of the steroid methylprednisolone (40 mg/mL) into each affected disc.
Study NCT04735185 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthetic
Description: In this intervention participants will receive a 1 mL intradiscal injection of the local anesthetic bupivacaine 0.5% into each affected disc.
Study NCT06443281 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Neurophysiology
Description: Pain-related evoked potentials and nerve conduction studies
Study NCT06311227 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT06443281 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiovascular test
Description: Blood pressure control, orthostatic intolerance test, baro-reflex sensitivity, heart-rate variability
Study NCT06443281 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Experimental pain paradigms
Description: Temporal summation of pain, conditioned pain modulation
Study NCT06565936 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: PET scan with tracer injection [18F] DPA-714 or [18F]F-FDG
Description: Brain PET/MRI imaging will be conducted following the administration of \[18F\] DPA-714 or \[18F\]F-FDG. The radiopharmaceuticals are given intravenously in doses that are safe for the human body, with minimal quantities to reduce potential effects. Additionally, the irradiation levels are kept low, ensuring the procedure is safe and reliable for patients.
Study NCT06565936 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: PET scan with tracer injection [18F] DPA-714 or [18F]F-FDG
Description: Brain PET/MRI imaging will be conducted following the administration of \[18F\] DPA-714 or \[18F\]F-FDG. The radiopharmaceuticals are given intravenously in doses that are safe for the human body, with minimal quantities to reduce potential effects. Additionally, the irradiation levels are kept low, ensuring the procedure is safe and reliable for patients.
Study NCT06311227 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT06552299 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laypersons
Description: 1. Participants will be asked to draw a 5cm line.~2. Participants will be asked to press a depth measuring device and resuscitation training manikin to depth of 5cm without and with assistance.
Study NCT06552299 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Health-Care Providers
Description: 1. Participants will be asked to draw a 5cm line.~2. Participants will be asked to press a depth measuring device and resuscitation training manikin to depth of 5cm without and with assistance.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Nivolumab
Description: Briefly, nivolumab is administered as an approximately 30-minute (240mg every 2 weeks) or 60-minute (480mg every 4 weeks) IV infusion. Nivolumab is to be administered first. The nivolumab infusion must be promptly followed by a saline flush to clear the line of nivolumab before starting the ipilimumab infusion.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Ipilimumab
Description: The second infusion will always be ipilimumab and will start at least 30 minutes after completion of the nivolumab infusion. Ipilimumab is to be administered as an approximately 30-minute IV infusion.~When administered together, nivolumab and ipilimumab will be administered on Day 1 of each 21-day cycle.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Pembrolizumab
Description: Pembrolizumab is to be administered as an approximately 30-minute IV infusion.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Cabozantinib
Description: Cabozantinib is a medication that is taken orally every day, once a day away from meals at the initial dose of 40 mg/day.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Axitinib
Description: Axitinib is a medication that is taken orally every day, 2 times a day continuously, at the starting dose of 5mg x2/day.
Study NCT06364631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Lenvatinib
Description: Lenvatinib is a medication that is taken orally every day, once a day at the initial dose of 20mg/day.
Study NCT05388708 — intervention group
Intervention type: DEVICE
Intervention: ECMO support
Description: ECMO prescribed by treating physicians for respiratory support in the setting of PARDS.
Study NCT05388708 — intervention group
Intervention type: OTHER
Intervention: PROSpect protocolized therapies
Description: PROSpect is testing the impact of supine/prone positioning and conventional mechanical ventilation (CMV)/high-frequency oscillatory ventilation (HFOV) on clinical outcomes in 1,000 children with severe PARDS. PROSpect manages severe PARDS subjects using a protocol that reserves ECMO for protocol failure.~The CMV group targets an exhaled tidal volume of 5-7mL/kg of ideal body weight and a peak inspiratory pressure \<28 cm of H2O. The positive end expiratory pressure (PEEP) and FiO2 are titrated by a PEEP-FiO2 titration grid. The HFOV group titrates the mean airway pressure to target a FiO2 \< 0.5 and a goal hemoglobin oxygen saturation of 88-92%. The frequency is titrated between 8-12 Hz and amplitude from 60-90 to achieve a goal pH of 7.15-7.30. Ventilation protocols are implemented until 28 days or extubation. Children randomized to the prone positioning will remain prone for at least 16 consecutive hours per day. Children randomized to supine positioning group remain supine.
Study NCT04251377 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Defensive Antiadhesive Coating DAC®, Novagenit SRL
Description: DAC gel, mixed with topical antibiotics is applied on the surface of the implants before implantation, in a sterile environment in the operating room.~The topical antibiotics will be added to the reconstituted DAC® gel preparation, at the discretion of the physician, on the basis of pre-operative culture.
Study NCT04963062 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Holmium laser with Moses lasers
Description: The holmium laser with Moses is FDA approved. It emits two separate laser pulses with a short time interval between them. The first pulse divides the water between the laser fiber tip and the stone and the second pulse hits the stone unobstructed. The goal is to increase stone ablative volume and decrease retropulsion of the stone.
Study NCT04963062 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Holmium laser with thulium lasers
Description: The holmium laser with thulium laser is FDA approved. It has a different wavelength then the holmium laser with Moses and thus has slightly different energy properties. It has also been shown to increase ablative volume and decrease retropulsion without any safety concerns
Study NCT06383013 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BB-101
Description: Subjects will be randomized to receive BB-101 or placebo, and expected 32 subjects for each arm.
Study NCT06383013 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: BB-101
Description: Subjects will be randomized to receive BB-101 or placebo, and expected 32 subjects for each arm.
Study NCT06312631 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Putting on the gripping glove
Description: taking measurements and putting the gripping glove on the patient
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ULPA questionnaire
Description: The evaluation of the effectiveness of the gripping glove on the performance of the upper limb in daily life will be evaluated using the ULPA score.~The investigator asks the patient to perform a task and the ULPA collects the total number of errors made by the patient (inability/omission, imprecision, repetition, time to complete the task)
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Activity Log (MAL) Questionnaire
Description: The MAL is a self-assessment of the integration of the upper limb into daily life. This measurement allows a quantified evaluation of the perceived performance of the use of the upper limb in the actions of daily life.~The patient will answer 30 questions about daily life and for each item, rate the quantity from 0 to 5: 0 = never uses the hemiplegic arm and 5 = uses as much as before the accident
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fugl-Meyer Assessment Upper Extremity (FMA-UE) questionnaire
Description: This questionnaire assesses the motor selectivity of the upper limb. Several questions are asked about the movements that the patient can perform and to each question, the patient can answer either 0 (minimum) and 2 (maximum).
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Score Action Arm Research Test
Description: This questionnaire evaluates 4 different actions: Grasping an object (6 different objects to grasp), holding an object (4 different objects), pinching an object (6 different objects) and the overall movements made by the patient (3 different overall movements).~For each item, each object or each movement evaluated, the patient must rate the task on a scale of 0 to 3 (0=cannot perform any part of the test and 3=performs the test normally)
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EuroQol five-level (EQ-5D-5L) questionnaire
Description: This questionnaire assesses the patient's state of health. 5 items are proposed (mobility, autonomy, current activity, pain, anxiety) and for each the patient must check one of the 5 propositions (no problem, mild problems, moderate problems, severe problems, incapable). The patient must also rate their state of health on a scale of 0 to 100.
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quebec User Evaluation of Satisfaction with Assistive Technology
Description: This questionnaire assesses satisfaction with the technical aid (here the gripping glove) and the related services. The technique and related services will be evaluated by items provided to the patient and he will have to rate for each of them a score between 1 and 5 (1 = not satisfied at all and 5 = very satisfied)
Study NCT06282406 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Stimulation
Description: Electrical pulse trains applied to the skin overlying putative sites of auricular vagal innervation.
Study NCT06282406 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: Electrodes placed on the skin overlying putative sites of auricular vagal innervation but no current administered.
Study NCT04792723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sublingual aspirin
Description: Vita Green Health Products sublingual aspirin 80 mg tablet
Study NCT04792723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral aspirin
Description: Synco (HK) oral aspirin 80mg tablet
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychosocial Impact of Assistive Devices Scale (PIADS)
Description: This questionnaire measures the effect of technical aids on the psychosocial level. 26 sentences or words are offered to the patient concerning his psychological state and the patient must evaluate them between -3 and 3 (-3 = decreased and +3: increased)
Study NCT06312631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Goal Attainment Scale (GAS)
Description: Carrying out an activity in the patient's real context is assessed using the Goal Attainment Scale (GAS). The doctor gives the patient objectives to achieve and the patient must give the quotation for each objective between initial state (-2), expected result (0) and best possible result (2)
Study NCT05823662 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: DJ stent
Description: A 5 Fr DJ stent will be inserted and then removed after three weeks.
Study NCT06323473 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Black Maitake Prothera
Description: Mushroom extract; liquid
Study NCT05453201 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Long COVID Coping and Recovery (LCCR) Intervention
Description: Veterans will participate in a LCCR (1x/week for a total of 16 sessions) via the HIPAA-compliant telehealth platform VA Video Connect (VVC) and/or VA WebEx with two co-therapists.
Study NCT06461273 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Medicine Program
Description: Participants will engage in culinary and nutrition education for 6 weeks curated by a professional chef working in conjunction with the project team from community partner Ethos Farm to Health. Lessons will be adapted from the American College of Lifestyle Medicine (ACLM) Culinary Medicine Curriculum~Participants will engage in exercise sessions on weeks without culinary and nutrition instruction for a total of 6 weeks. Exercise sessions will include a variety of activities to include calisthenics, weight training, walking, running, dance, and games delivered by the Rutgers physical therapy team.~Urban Agriculture lessons will occur longitudinally throughout the 12-week course. Participants will learn to cultivate a variety of crops in limited spaces, emphasizing sustainable practices and the importance of local food systems in urban communities.~Additionally, this arm will receive a supplemental food box weekly consistent with the dietary pattern set forth by ACLM.
Study NCT06461273 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Medically Tailored Groceries
Description: Participants in the Food is Medicine arm will receive a supplemental food box weekly curated by a registered dietician and dietetics students. Each food box will contain seasonally available fruit and vegetables and other items including protein, dairy/cheese, and legumes that may be available at the time of the food box delivery. Each box will contain approximately 8 pounds of food and all participants in this group will receive the same food items. Classes and educational materials provided will be tailored to the specific foods contained in the weekly food box and will include simple preparation methods, recipes, nutrition information and grocery shopping tips.
Study NCT06443281 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Quantitative sensory testing
Description: Thermal and mechanical sensory testing
Study NCT06443281 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical pain phenotype
Description: Pain drawings, plus and minus signs of pain
Study NCT06004115 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lorazepam
Description: 1mg of Lorazepam will be prepared by pharmacy (Barnes, Tulsa) in capsule form
Study NCT06004115 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo will be prepared by pharmacy (Barnes, Tulsa) in capsule form
Study NCT06649747 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: AFA-281
Description: A small molecule, orally available
Study NCT06649747 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: AFA-281
Description: A small molecule, orally available
Study NCT06232122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46
Description: Intravenous injection of one dosage of 2 mCi 68Ga-FAPI-46
Study NCT06232122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-FDG
Description: Intravenous injection of one dosage of 5-10mCi 18F-FDG
Study NCT04977999 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Both arms/conditions use varying forms of exercise as the intervention.
Study NCT04977999 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Both arms/conditions use varying forms of exercise as the intervention.