AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05419050 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: denosumab
Description: monoclonal antibody to receptor activator of nuclear kappa-B ligand (RANKL), a protein involved in regulating osteoclastogenesis
Study NCT04843527 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FreeStyle Libre System
Description: FreeStyle Libre Flash Glucose Monitoring System
Study NCT04843527 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FreeStyle Libre System plus food app
Description: FreeStyle Libre Flash Glucose Monitoring System and Smartphone Food Logging application
Study NCT05834673 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: SMS messages
Description: Participants will receive monthly SMS messages regarding cardiovascular health (low touch engagement nudges)
Study NCT05834673 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Telephone-based support calls
Description: Participants will receive telephone-based support calls from a study nurse trained in motivational interviewing. These telephone calls will cover diet, exercise, medication, and where necessary smoking cessation. A summary of any recommendations will then be sent to the primary care physician via email or letter.
Study NCT05834673 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: GP Education
Description: Education of GPs on the European Society of Cardiology (ESC) guidelines and Guideline Directed Management Therapy
Study NCT06611891 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-DOTATOC
Description: Slow direct intravenous injection
Study NCT05439200 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Asynchronous 3D movies
Description: 3D movies streamed at home for viewing on a handheld lenticular 3D screen
Study NCT05439200 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Patching
Description: Adhesive patch to cover the fellow eye
Study NCT05455294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Navitoclax
Description: See Arm Description
Study NCT05455294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: See Arm Description
Study NCT05455294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: See Arm Description
Study NCT05818462 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Uroflow testing
Description: Uroflowmetry is a test that measures the volume of urine released from the body, the speed with which it is released, and how long the release takes.
Study NCT05818462 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bladder Scan
Description: Bladder scan measures ultrasonic reflections within the patient's body to differentiate the urinary bladder from the surrounding tissue. In this case, it is used to detect the volume of urine in the bladder.
Study NCT05818462 — intervention group
Intervention type: OTHER
Intervention: Dysfunctional Voiding Scoring System Survey
Description: The Dysfunctional Voiding Symptom Score to provide accurate and objective numerical, grading of voiding behaviors of children.
Study NCT05818462 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: DEXA Scan of pelvis and sacral spine
Description: DEXA (dual x-ray absorptiometry) scans measure bone density (thickness and strength of bones) by passing a high and low energy x-ray beam (a form of ionizing radiation) through the body, usually in the hip and the spine.
Study NCT05818462 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Urine tests for specific biomarkers
Description: Urine tests for specific biomarkers (ATP, NGF, BNDF and urine proteomic screening).
Study NCT06650475 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Using low or standart pressure
Description: Written consent will be obtained before the randomized study. Randomization will be done on the computer using a software program. Participants will be divided into two groups. Patients in Group S will undergo laparoscopy under standard pressures (12-16 mmHg) in laparoscopic surgery, while patients in Group L will undergo laparoscopy under low pressure (8-10 mm Hg).
Study NCT06650475 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Using low or standart pressure
Description: Written consent will be obtained before the randomized study. Randomization will be done on the computer using a software program. Participants will be divided into two groups. Patients in Group S will undergo laparoscopy under standard pressures (12-16 mmHg) in laparoscopic surgery, while patients in Group L will undergo laparoscopy under low pressure (8-10 mm Hg).
Study NCT06596473 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BG-C477
Description: Administered intravenously.
Study NCT06596473 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Administered in accordance with relevant local guidelines and/or prescribing information.
Study NCT05566639 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1010
Description: Sterile liquid for injection
Study NCT06668363 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treat4All
Description: An alcohol reduction evidence-based intervention integrated with HIV status-neutral counseling
Study NCT06668363 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care (control arm)
Description: Sexual risk reduction counseling
Study NCT06668363 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard of care (control arm)
Description: Sexual risk reduction counseling
Study NCT06021769 — intervention group
Intervention type: OTHER
Intervention: Observational only
Description: No intervention
Study NCT06614738 — intervention group
Intervention type: OTHER
Intervention: Sampling of feces and duodenal fluids
Description: * Blood sampling (plasmotheque and serotheque): 2 tubes (EDTA (5mL) and dry (5mL)) during hospitalization~* Fecal sampling (fecal library): A stool sample (approx. 2g) will be taken 48 hours before the endoscopy at home for outpatient or during hospitalization~* Duodenal aspiration fluid (6-10 mL in total): before and after mucosal lavage with sterile isotonic saline on the day of endoscopy.~* Food and Lifestyle Questionnaire (FFQ) during inclusion
Study NCT06614192 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-400
Description: Intravenous (IV) Infusion
Study NCT06614192 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trifluridine/Tipiracil
Description: Oral Tablet
Study NCT06614192 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: IV Infusion
Study NCT06660290 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.003% AR-15512 ophthalmic solution
Description: Investigational ophthalmic solution for topical instillation
Study NCT06660290 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REFRESH® Classic ophthalmic solution
Description: Commercially available ophthalmic solution for topical instillation
Study NCT05691465 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood
Study NCT05691465 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT scan
Study NCT05691465 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Gallium Ga 68-DOTATATE
Description: Given IV
Study NCT05691465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium Lu 177 Dotatate
Description: Given IV
Study NCT05691465 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET
Study NCT06669091 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Ecopipam tablet
Description: A single ecopipam 89.6 mg tablet (equivalent to ecopipam HCl 100 mg)
Study NCT05374109 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SYV: Sauti ya Vijana (The Voice of Youth intervention)
Description: Mental health is associated with ART adherence and HIV outcomes. SYV was designed to address the specific challenges of young people living (YPLWH) with HIV in Tanzania. SYV includes 10 group sessions (two sessions held jointly with caregivers) lasting approximately 90 minutes and two individual sessions delivered by trained young adult group leaders who use a manualized protocol that is designed to scale in low resource settings. The intervention is applied to the Social Action Theory (SAT), a theoretical framework used to determine factors that influence health behavior. Building off a SAT resilience framework for YPLWH, components of evidence-based treatment models to influence cognitive, self, and social regulation to improve behavioral health outcomes will be strategically used.
Study NCT06349109 — intervention group
Intervention type: OTHER
Intervention: Cardiopulmonary exercise test
Description: The cardiopulmonary exercise test (CPET), the gold standard for the assessment of cardiorespiratory fitness, will be used. The Modified Bruce/half Bruce protocol with will be used. In addition, dyspnoea, leg fatigue and general fatigue will be recorded every three minutes at rest, during the test and during the post-test recovery phases using the Modified Borg Scale and blood pressure will be recorded with a sphygmomanometer. The test will be continued until individuals reach the end of the protocol or until the last point at which they wish to stop the test. The test will be terminated if the patient wishes to terminate the test, severe breathlessness, leg fatigue or general fatigue, loss of coordination, progressive chest pain, ST segment elevation or depression of more than 2 mm, oxygen saturation of 80% or less, reaching 85% or more of the predicted heart rate. Oxygen consumption (VO2peak) will be used as the primary outcome measure for cardiorespiratory fitness.
Study NCT06349109 — intervention group
Intervention type: OTHER
Intervention: Atrial-Ventricular Strain Analysis
Description: Atrial-Ventricular strain will be evaluated by a specialist physician using Speckle Tracking Echocardiography. During the evaluation, standard echocardiographic measurements will be made with transthoracic echocardiography. With these measurements, images suitable for strain analysis will be obtained. Deformation analysis will be performed using the speckle tracing method for the appropriate images obtained and hemodynamic parameters obtained by the analysis will be recorded.
Study NCT06349109 — intervention group
Intervention type: OTHER
Intervention: Arterial Stiffness Measurement
Description: Arterial stiffness will be assessed using the pulse wave velocity (PWV) technique with the Mobile-O-GRAPH (TG) (LE.M., Stolberg, Germany), an oscillometer-based device. After the patients have rested sufficiently, measurements will be taken in an upright sitting position in a quiet and sufficiently bright environment at room temperature, with the device manso placed 2-3 cm above the chiibital fossa in the non-dominant upper limb and the arms raised to the level of the heart. Pulse propagation velocity will be calculated in m/sec with the help of a computer. A high velocity data indicates a high level of arterial stiffening and a low velocity data indicates a low level of arterial stiffening.
Study NCT06349109 — intervention group
Intervention type: OTHER
Intervention: Physical Activity Level
Description: Physical activity level will be assessed with the Child Physical Activity Questionnaire.
Study NCT06349109 — intervention group
Intervention type: OTHER
Intervention: Physical Activity Barriers Assesment
Description: Physical Activity Outcome Expectancies (child survey) and Physical Activity Home Environment Scale (Child) will be used in children, while  Physical activity barriers (Parent) will be used in family members.
Study NCT04862468 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Perivascular dexamethasone
Description: Dexamethasone delivery around target vein segment(s)
Study NCT04862468 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: SHAM_COMPARATOR
Intervention: Perivascular sham
Description: Saline delivery around target vein segment(s)
Study NCT05566639 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Fluarix Quadrivalent
Description: Sterile suspension for injection.
Study NCT05934396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Safety Planning
Description: Prior to discharge and following the conclusion of all Virtual Reality (VR) sessions, the participant will develop a safety planning intervention for school settings in collaboration with relevant individuals (e.g., the researcher, a school professional).
Study NCT05934396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VR Enhanced Affect Regulation
Description: Participants will receive an overview of affect regulation in VR and then have the opportunity to practice using affect regulation in a brief immersive experience designed to mimic difficult school experiences. Each session begins with goal setting prior to the VR experience and concludes with a debrief summary following the VR experience.
Study NCT05934396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VR Enhanced Cognitive Restructuring
Description: Participants will receive an overview of cognitive restructuring in VR and then have the opportunity to practice using cognitive restructuring in a brief immersive experience designed to mimic difficult school experiences. Each session begins with goal setting prior to the VR experience and concludes with a debrief summary following the VR experience.
Study NCT05934396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VR Enhanced Problem Solving
Description: Participants will receive an overview of problem solving in VR and then have the opportunity to practice using problem solving in a brief immersive experience designed to mimic difficult school experiences. Each session begins with goal setting prior to the VR experience and concludes with a debrief summary following the VR experience.
Study NCT05934396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy (CBT) Worksheets
Description: The researchers will provide instructions for participants to complete a packet of worksheets teaching introduction to cognitive behavioral therapy (CBT), affect regulation, cognitive restructuring, and problem solving.
Study NCT06605404 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: blood and tissue samples
Description: routine standard of care
Study NCT06605404 — intervention group
Intervention type: OTHER
Intervention: blood and tissue samples
Description: Routine standard of care
Study NCT06606925 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: fMRI with virtual reality flight simulator
Description: During this scan, the subject will be wearing the stereogenic goggles called the Visual System HD (NordicNeuroLab) mounted in the scanner via a headcoil that can be adjusted to the subject's comfort using the control arm and completely cover the eyes to prevent light exposure and to clearly visualize eye movement during the flight simulation. The subject will be using a visual response system with customized grips to simulate a stick and throttle in a jet cockpit while visualizing the flight simulation (PICT) in the goggles.
Study NCT05846789 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOC Chemotherapy
Description: SOC Chemotherapy will be given AUC 6 IV q3 weeks for a maximum of 9 infusions.
Study NCT05846789 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SOC Chemotherapy
Description: SOC Chemotherapy will be given AUC 6 IV q3 weeks for a maximum of 9 infusions.
Study NCT06538220 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires and focus group
Description: To evaluate the Chronic Disease Unit care pathway, patients will respond to questionnaires : quality of life (SF-12), personal efficacy scale (GSES), Specific self Efficacy related to Weight Management (SEWM), Rosenberg self-esteem, body image satisfaction (QIC), state of anxiety and depression (HAD), Chronic Disease Unit satisfaction. Some patients will also participate to focus group.
Study NCT05520060 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical support
Description: Pharmacological and non-pharmacological methods in pain management, Mobilization, Position preferred by the woman, Fluid and nutritional support, Massage applications, Sacral pressure, Listening to music, Breathing and relaxation exercises
Study NCT05520060 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychospiritual support
Description: Effective communication, Encouragement to speak up and express fears, Support for faith-oriented practices
Study NCT05520060 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Environmental and sociocultural support
Description: egulating the temperature, light and sound of the room, Environment that promotes respect for privacy, Reducing environmental noise, Information, Social support, Talking about cultural practices, Social support
Study NCT05520060 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Routine care
Description: Admission to the delivery room, preparation for birth, delivery, postpartum care, etc.
Study NCT05520060 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine care
Description: Admission to the delivery room, preparation for birth, delivery, postpartum care, etc.
Study NCT05860452 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ropivacaine
Description: single shot bilateral TAP block
Study NCT05860452 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: single shot bilateral TAP block
Study NCT06671093 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Tune-401
Description: Epigenetic gene silencing therapy
Study NCT06671184 — intervention group
Intervention type: OTHER
Intervention: Observations on clinicopathological factors influencing the difficulty of surgery
Description: Age, body mass index, gender, thyroid function parameters, lesion size, lesion location, ultrasound data
Study NCT06616324 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Participants in the intervention group will undergo ESWL according to standard treatment but with the addition of Virtual Reality and ANC-headphones as a supplement.
Study NCT05564273 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: VIOME Precision Nutrition Program
Description: Precision supplement based on the participants microbiome sample results. Participants in this arm may receive supplements, diet recommendations, and app coaching.
Study NCT05564273 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: VIOME-designed condition-based supplements
Description: Pre-formulated supplements based on overall health conditions. Participants in this arm may receive supplements, diet recommendations, and app coaching.
Study NCT06667141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ACR-2316
Description: ACR-2316 is an experimental drug
Study NCT06668636 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ED-PATCH
Description: Participants will access ED-PATCH using their personal mobile device and use it to track important information throughout their visit. The summary will be checked by a healthcare provider and corrected, if necessary, before being locked and sent to the patient or caregiver to keep for their own records.
Study NCT06613360 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CLN-978
Description: Specified dose on specified days
Study NCT06469138 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bemcentinib
Description: Each 200 mg dose contains approximately 32.8 μCi (1.21 MBq) of 14C-bemcentinib and is administered as a single dose on Day 1 of the study.
Study NCT06195163 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal Gel in Sachet Dosage Form
Description: Transdermal testosterone gel application prior to ovarian stimulation in the study group.
Study NCT06195163 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: No pretreatment
Description: No pretreatment prior to the ovarian stimulation in the control group.
Study NCT06057909 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic Resonance Imaging
Description: Test that looks at the structure of the brain.
Study NCT05846789 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab
Description: Tocilizimab 8 mg/ actual body weight in kg IV q4 weeks
Study NCT06057909 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Electroencephalography
Description: Non-invasive technique to measure brain waves
Study NCT06057909 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Electromyography
Description: Technique to evaluate muscle activity
Study NCT06674811 — intervention group
Intervention type: OTHER
Intervention: Wearing Smartwatch
Description: Patients and their caregivers will be asked to start wearing a smartwatch prior to surgery and continuing to wear it for one year following surgery at all times except when bathing or swimming, eating, undergoing a procedure, or if refusing to wear them. The smartwatches collect motor activity by minutes spent being sedentary, active, or highly active, heart rate, and sleep duration and stages. Data from the smartwatches syncs with Garmin connect using Fitabase to allow the study team to review the data.
Study NCT06674811 — intervention group
Intervention type: OTHER
Intervention: Patient Report Outcomes
Description: To obtain patient-reported outcomes (PROs), questionnaires will be administered at time of enrollment, in the two weeks prior to surgery if applicable, and at 1, 2, 4, 8, 12, 16, 20, 24, 34, 44, and 54 weeks postoperatively. Questionnaires can be completed electronically, over the telephone or in person. The PedsQL Cancer Module and Patient Health Questionnaire depression scale (PHQ-9) will be utilized for questionnaires.