AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05970562 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conversation Training Therapy
Description: CTT is a 4-week (1 45-minute session per week) evidence-based voice therapy for patients with VH, developed primarily to maximize the amount and speed of generalization outside the therapy session. It consists of 3 required targets: Decreased overall auditory-perceptual voice severity, improved discrimination between baseline and improved voicing, and adherence to CTT recommendations in daily life. The three optional targets are decreased overall auditory-perceptual severity across an increased pitch range, loudness range, and decreased rate of speech. All voice-related targets are modified through practicing voicing with increased forward resonance and mean airflow in spontaneous speech/conversation.
Study NCT05513443 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Irreversible electroporation, IRE
Description: IRE involves the use of high voltage electrical pulses to treat solid tumors by increasing membrane permeability and inducing membrane disruption, leading to cell death. The technique is used in Sweden today in radical ablative therapies in the treatment of tumors in the liver, kidney and pancreas. Prior to treatment a Foley catheter is placed. During the treatment, which takes place under anesthesia, the patient is placed in gynecological position and the tumour lesion is located with BK transrectal fusion ultrasound. Thereafter the needles are placed transperineal around the tumor in the prostate using a brachytherapy grid (17Ga Civco brachytherapy grid), guided by the ultrasound/MRI fusion images. Through the needles electrical pulses are then sent to treat the tumor in the center using the Nanoknife technique. After treatment patients are treated with diuretics to flush the kidneys post treatment.
Study NCT05513443 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radical prostatectomy
Description: Radical prostatectomy
Study NCT05513443 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiation therapy
Description: Radiation therapy for prostate cancer
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: riliprubart
Description: Pharmaceutical form:Solution-Route of administration:IV solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form:Solution-Route of administration:IV solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: riliprubart
Description: Pharmaceutical form:Solution-Route of administration:SC solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: riliprubart
Description: Pharmaceutical form:Solution-Route of administration:SC solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form:Solution-Route of administration:SC solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IVIg
Description: Pharmaceutical form:Concentrate for solution for infusion (or any other formulation approved locally)-Route of administration:IV solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Pharmaceutical form:Placebo to match intravenous immunoglobulin IVIg for IV infusion-Route of administration:IV solution
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IVIg premedication
Description: Pharmaceutical form:Per respective labels-Route of administration:Per respective labels
Study NCT06290141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IVIg premedication
Description: Pharmaceutical form:Per respective labels-Route of administration:Per respective labels
Study NCT04777331 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prasinezumab
Description: Prasinezumab will be administered as an IV infusion to participants Q4W.
Study NCT04777331 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Prasinezumab placebo will be administered to participants.
Study NCT06214455 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low sugar diet and 10-12 hour eating window
Description: Low sugar diet and 10-12 hour eating window for four weeks
Study NCT06214455 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low sugar diet, 8 hour eating window and fasting
Description: Low sugar diet, 8 hour eating window and a 36-60 hour fast once per week for four weeks.
Study NCT05745285 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LLS Program
Description: The intervention will be conducted virtually. Participants will receive LLS's free patient and caregiver services including co-pay assistance, transportation and urgent need assistance, a scholarship program for young adult patients and survivors, one-on-one peer-to-peer support, online chats and support groups facilitated by clinical social workers, and nutrition counseling with a registered dietician for 6 months.
Study NCT04889924 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Axillary Radiotherapy
Description: Axillary radiotherapy without lymphadenectomy (level I and II) + level III and supraclavicular +/- internal mammary chain
Study NCT04889924 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Lymphadenectomy
Description: Axillary Lymph node dissection
Study NCT05552755 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REC-4881
Description: REC-4881 4mg capsules
Study NCT05552755 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules
Study NCT05979831 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DS-2325a
Description: Main Phase and Extension Phase: Loading IV dose followed by maintenance SC doses
Study NCT05979831 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Main Phase: IV infusion followed by SC doses
Study NCT05608512 — intervention group
Intervention type: OTHER
Intervention: interview
Description: The first phase included a qualitative study. We conducted a qualitative phenomenological method to better explicate and understand palliative care nurses' emotional labor experiences, as well as the dilemmas and solutions they encounter when physical, mental, and emotional labor intertwine at work. In the early stage, we compiled an interview outline by a written qualitative meta-analysis about the emotional labor, and added the contents in the interview outline according to the actual situation in the later interview process.
Study NCT06126393 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: next generation sequencing AND Immunohistochemical examination
Description: First, the mismatch repair (MMR) proteins were detected by immunohistochemistry, and the deletion of one or more proteins was classified as d-MMR subtype; Then the POLE gene mutation detection was performed, and the mutation Changes were classified as POLE mutation; Finally, p53 was detected by immunohistochemistry, and p53 mutant (p53 abn) and p53 wild-type (p53wt) were distinguished.
Study NCT05569369 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: angioplasty and stenting
Description: dilatation of stenotic arteries and insertion of stent
Study NCT05502952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline
Description: Combined microneedling and topicalpentoxifylline vesrus intalesional pentoxifylline in Alopecia Areata patches in the same patient
Study NCT06312397 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acupressure
Description: For the acupressure group, a total of three points will be applied: the heart meridian 7th point (HT7), the large intestine meridian 4th point (LI4), and the stomach meridian 36th point (ST36), which is deemed appropriate in the lower extremity The symmetry of the three selected different points will also be applied to the other extremity.~After coronary angiography, acupressure will be applied for a total of 15 minutes.
Study NCT06312397 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham acupressure
Description: In the acupressure application applied to the sham group, parallel pressure will be applied to the bone area and points where the HT7, LI4, ST36 meridians do not pass.
Study NCT06180434 — intervention group
Intervention type: RADIATION
Intervention: proton therapy
Description: Radiotherapy delivered with protons
Study NCT06180434 — intervention group
Intervention type: RADIATION
Intervention: photon therapy
Description: Radiotherapy delivered with photons
Study NCT05586425 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Regulation Skills + Treatment as Usual
Description: ERS has been updated to be friendlier to youth and involves learning skills for how to: (1) be more present in the moment, (2) effectively manage and respond to emotional experiences, (3) communicate your needs to others, and (4) increase your ability to tolerate distress.
Study NCT05586425 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: Treatment as Usual entails psychiatric medication management, psychiatric management, individual support from peer mentors, drop-in activity groups, etc.
Study NCT05919082 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LEO 90100
Description: Subjects will apply LEO 90100 topically; up to 15 g per day (or 105 g per week).
Study NCT05919082 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Daivobet® ointment
Description: Subjects will apply Daivobet® ointment topically; up to 15 g per day (or 105 g per week).
Study NCT05886114 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Structured Multi-domain Intervention
Description: Structured Multi-domain Intervention (SMI) involves providing participants with intensive structure and support by a team of trainers to increase physical exercise, adhere to a healthy diet, cognitive training, increase intellectual/social stimulation, and better manage vascular risk factors.
Study NCT05886114 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Guided Intervention
Description: In the Self-Guided Intervention (SGI), education about the importance of a healthy lifestyle as a preventive strategy and support to encourage change will be provided.
Study NCT05359952 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Starting the Conversation
Description: The Starting the Conversation intervention consists of a brief educational video and accompanying workbook with activities to help prepare patients to discuss sexual and menopausal types of health concerns effectively with gynecologic cancer providers, including prioritizing concerns, tips for effective communication, communication practice, and self-feedback. In addition, participants receive a list of sexual and menopausal resources.
Study NCT05359952 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sexual and Menopausal Health Resources Only
Description: A list of resources on sexual/menopausal health both within and outside the institution, including websites.
Study NCT05359952 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sexual and Menopausal Health Resources Only
Description: A list of resources on sexual/menopausal health both within and outside the institution, including websites.
Study NCT04437914 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Electrocardiogram diagnosis
Description: Electrocardiographic diagnosis will be made in a double-blind manner by two specialists in cardiology and cardiac arrhythmias and the results will be compared between the groups studied.
Study NCT05713110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tazemetostat
Description: Dose Escalation Phase (Phase IIa):~Tazemetostat (800 mg BID orally) in a therapeutic cycle of 28 days;~Dose Expansion Phase (Phase IIb):~Tazemetostat (800 mg BID orally) in a therapeutic cycle of 28 days
Study NCT05713110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HMPL-689
Description: Dose Escalation Phase (Phase IIa):~HMPL-689:20 mg and 30 mg, QD orally in a therapeutic cycle of 28 days.~Dose Expansion Phase (Phase IIb):~HMPL-689 (RP2D) in a therapeutic cycle of 28 days
Study NCT05294042 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Navigation
Description: The intervention in this study is a model of navigation for families seeking services at the two mental health agencies collaborating on this study. Navigators will implement a model of navigation with caregivers focused on reducing logistical and attitudinal barriers to care.
Study NCT04947397 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pupillometry
Description: Pupillometry prior to extubation
Study NCT05864313 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: 10 Hz rTMS for 5 seconds over the frontal eye fields with 25 second intertrain interval for 10 trains (500 pulses) at 90% of the resting motor threshold,
Study NCT05864313 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gait training
Description: Subjects will practice stepping on virtual targets with real-time feedback of their foot position displayed on a screen while walking on a treadmill.
Study NCT05864313 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Gait training
Description: Subjects will practice stepping on virtual targets with real-time feedback of their foot position displayed on a screen while walking on a treadmill.
Study NCT05864313 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gaze training
Description: Subjects will perform gaze stabilization and gaze shifting exercise via a virtual reality headset.
Study NCT05864313 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Gaze training
Description: Subjects will perform gaze stabilization and gaze shifting exercise via a virtual reality headset.
Study NCT05864313 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham rTMS
Description: Sham rTMS stimulation will produce discharge noise and vibration without stimulating the cerebral cortex.
Study NCT03329157 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Rebuilding Bridges
Description: Psychosocial intervention to help veterans re-engage with family members called Rebuilding Bridges, developed for this project.
Study NCT05888792 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Variant of Defocus Incorporated Spectacle lens (DG2)
Description: DG2 is a variant of Defocus Incorporated Spectacle lens that corrects the distance refraction and provides myopic defocus simultaneously
Study NCT05145192 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: COSMED K5 CPET (Cardiopulmonary Exercise Test)
Description: In this randomized crossover trial of eligible adults, we will compare peak measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) during three maximal cardiopulmonary stress exercise tests (CPET), each seven to ten days apart. Subjects will be randomized into either the K5 or ParvoMedics (PM) group for their first CPET using a 1:1 randomization scheme and will serve as their own control in the subsequent test seven to ten days after the previous one. After both a K5 and a PM CPETs have been completed, the participants will complete an additional K5 CPET for test-retest reliability. A within-subjects analysis will be performed.
Study NCT05145192 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: COSMED K5 CPET (Cardiopulmonary Exercise Test)
Description: In this randomized crossover trial of eligible adults, we will compare peak measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) during three maximal cardiopulmonary stress exercise tests (CPET), each seven to ten days apart. Subjects will be randomized into either the K5 or ParvoMedics (PM) group for their first CPET using a 1:1 randomization scheme and will serve as their own control in the subsequent test seven to ten days after the previous one. After both a K5 and a PM CPETs have been completed, the participants will complete an additional K5 CPET for test-retest reliability. A within-subjects analysis will be performed.
Study NCT05145192 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ParvoMedics CPET
Description: ParvoMedics CPET
Study NCT05145192 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ParvoMedics CPET
Description: ParvoMedics CPET
Study NCT06096272 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Augment Reality Exergames
Description: Adaptive physical activity AR gaming modules were created in collaboration with physical therapists with expertise in CP and the Augment Therapy app development team. The program will consists of 5 games adapted for children with cerebral palsy.
Study NCT05866627 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine
Description: Specified dose on specified days
Study NCT05866627 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afimetoran
Description: Specified dose on specified days
Study NCT05842070 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low-Intensity Egg Freezing Protocol
Description: The low-intensity egg freezing protocol involves fewer ultrasounds, bloodwork and injections, contributing to a lower cost. Otherwise, this protocol does not differ significantly from the other routine high-intensity clinic protocols.
Study NCT05842070 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High-Intensity Egg Freezing Protocol
Description: The high-intensity egg freezing protocol is a routinely used clinic protocol where patients are coming for frequent ultrasounds and bloodwork, as well as more injections, contributing to a higher overall cost for egg-freezing.
Study NCT06561958 — intervention group
Intervention type: DRUG
Intervention: REKOVELLE
Description: Individualised dosing regiment of REKOVELLE in routine clinical practice.
Study NCT06560476 — intervention group
Intervention type: OTHER
Intervention: Data collection
Description: Subject's data will be collected from patients that are undergoing care using the Optilume drug-coated catheter system.
Study NCT06517628 — intervention group
Intervention type: OTHER
Intervention: Purely observational study on the care and outcomes of participants with cardiovascular disease in pregnancy.
Description: The primary exposure variable is the organization of cardio-obstetrics care which will be defined by annual site surveys and its association with outcomes will be defined by hierarchical models adjusting for patient characteristics.
Study NCT06134154 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Endoscopic insufflation gas
Description: Carbon dioxide gas versus air for endoscopic insufflation
Study NCT06134154 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Endoscopic insufflation gas
Description: Carbon dioxide gas versus air for endoscopic insufflation
Study NCT06289166 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STSP-0601 for Injection
Description: A Multiple-dose Design to Evaluate the Safety, Tolerability and Efficacy of STSP-0601 for Injection in hemophilia A or B patients with inhibitor.
Study NCT05877963 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ublituximab
Description: Administered as an IV infusion.
Study NCT04069013 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PCNL
Description: Patients receive standard of care treatment for their urolithiasis using one of two surgical procedures, either standard PCNL or Mini-PCNL
Study NCT05433454 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Outreach From Navigators
Description: Navigators are professionals who can provide one-on-one assistance with the Medicaid renewal process. The nature of the outreach will be randomized to participants.
Study NCT05258682 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bromelains
Description: Bromelain combined with Acetylcysteine (BromAc), administered simultaneously.
Study NCT05258682 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetylcysteine
Description: Bromelain combined with Acetylcysteine (BromAc), administered simultaneously.
Study NCT06218771 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3454 Tablets
Description: TQB3454 Tablets is a selective isocitrate dehydrogenase 1 (IDH1) mutation inhibitor
Study NCT05737121 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VNX001
Description: VNX001 (alkalinized lidocaine HCl and heparin sodium)
Study NCT05737121 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inactive placebo for VNX001
Study NCT05737121 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine
Description: Alkalinized lidocaine hydrochloride
Study NCT05737121 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Heparin
Description: Alkalinized heparin sodium
Study NCT05608356 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: injectable platelet rich fibrin(i-prf)
Description: I-prf is a second-generation PRP where autologous platelets and leukocytes are present in a complex fibrin matrix and can be obtained from blood using low-speed centrifugation without adding anticoagulants.
Study NCT05608356 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Sham Injection
Description: Sham injection as a placebo injection
Study NCT05898568 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality
Description: In addition to the routine hand rehabilitation programs for 4 weeks, 5 days, 40 minutes a day, 20 sessions (4 weeks, 5 days a week, 20 minutes) virtual reality based movement therapy program will be applied.
Study NCT05898568 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: routine treatment
Description: 20 sessions (4 weeks, 5 days a week, 60 minutes) routine hand rehabilitation program will be applied.