AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06692920 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DBS stimulation
Description: * Standard of care DBS surgery~* stimulation through the DBS lead during their DBS lead surgery, the study team will use 2 sets of stimulation settings on each participant:~  1. Stimulation through the DBS contact whose electrical activity is the MOST similar to the area of the brain that controls movement~ 2. Stimulation through the DBS contact whose electrical activity is the LEAST similar to the area of the brain that controls movement
Study NCT06699602 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: cemiplimab IV flat
Study NCT06699602 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fianlimab
Description: fianilmab IV flat
Study NCT06701422 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraoperative stimulation of the cervical spinal cord
Description: The surgeon will place spinal cord electrodes on the epidural surface, with stimulation sites identified using preoperative MRI. Recruitment curves will be generated by systematically increasing the stimulation intensity across various parameter combinations, including frequency, pulse count, pulse shape, and electrode-specific properties such as size, separation, and arrangement.
Study NCT06693284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mirdametinib and vorinostat
Description: short course of the combination of mirdametinib and vorinostat prior to the most appropriate standard of care treatment for the patient's specific tumor (typically localized radiation followed by surgical resection).
Study NCT06423781 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BHV-7000
Description: BHV-7000 75 mg taken once daily
Study NCT06704217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Six Spot Step Test
Description: The Six-Spot Step Test (SSST), which evaluates balance and functional ambulation, will be performed in an area 5 meters long and 1 meter wide. Five wooden cylinders will be arranged in a zig-zag pattern within this space, with the last cylinder positioned at the centerline. The participant will be asked to strike the wooden cylinders with the medial or lateral side of the same foot and push them outward. The test will be repeated twice with the dominant foot and twice with the non-dominant foot. A trial will be conducted before the test to familiarize participants with the procedure. A two-minute rest period between the test and trials will be provided to minimize fatigue effects. The test's inter-rater reliability will be assessed by two physiotherapists with more than 5 years of clinical experience, who will administer the test twice at 5-minute intervals.
Study NCT06704217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Oxford Hip Score
Description: The Oxford Hip Score will be used for functional level assessment.
Study NCT06704217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Berg Balance Scale
Description: The Berg Balance Scale (BBS) will be used to assess dynamic balance, which is reliable and commonly used within the orthopedic setting.
Study NCT06704152 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOC + BSB-1001 Dose Escalation Cohort
Description: Patients will receive BSB-1001 a single intravenous (IV) infusion on day 0 following the infusion of the CD34-allo hematopoietic stem cell transplant (HCT).
Study NCT06704152 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SOC+BSB-1001 Expansion Dose
Description: Patients will receive BSB-1001 a single intravenous (IV) infusion on day 0 following the infusion of the CD34-allo hematopoietic cell transplant (HCT).
Study NCT06728579 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Oriented Recovery Enhancement (MORE)
Description: eight weekly two-hour MORE sessions
Study NCT06728579 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: filled out up to 24 weeks
Study NCT06728579 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaires
Description: filled out up to 24 weeks
Study NCT06728579 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supportive Psychotherapy (SG)
Description: eight weekly two-hour SG sessions
Study NCT04960475 — intervention group
Intervention type: OTHER
Intervention: The MOS 36-Item Short From Health Survey (SF-36)
Description: The SF-36 is a multi-purpose survey designed to capture adult patients' perceptions of their own health and well-being. The SF-36 has 36 items grouped in 8 dimensions: physical functoning, physicial and emotional limitations, social functioning, bodily pain, general and mental health.
Study NCT06539299 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Socket Preservation
Description: After extracting a tooth, the alveolar socket is cleaned. A bone replacement material (Bio-Oss Collagen) is then placed into the socket and sutured with a collagen membrane (Mucograft-Seal). Patients will receive Antibiotics (Augmentin 875mg/125mg OR Dalacin C 300mg) and pain medication (Seractil forte 400 mg). Patients will be advised to carefully rinse with Chlorhexamed forte for one week. Sutures will be removed after two weeks.
Study NCT04800107 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Curcumin-phosphatidylcholine
Description: 500 mg of curcumin-phosphatidylcholine combined with 250 mg of boswellia-phosphatidyl
Study NCT04800107 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsule
Description: Placebo capsule
Study NCT04987177 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Workload of Manual Wheelchair Propulsion
Description: Participants will complete 20 one-minute manual wheelchair propulsion bouts. Each one minute propulsion bout will be followed by a 2 minute rest period. Each propulsion bout will be at a different workload. After every 10 propulsion bouts, participants will be provided with an extended rest period (5 to 30 minutes). For each participant, the maximum workload to be tested is based on their estimated maximum workload. Estimate maximum workload is based on the HR-Workload relationship documented during a prior sub maximal test to 80% of age adjusted maximum heart rate.
Study NCT05970601 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soup
Description: Intake of a single soup with different sodium chloride and potassium chloride content
Study NCT05970601 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Soup
Description: Intake of a single soup with different sodium chloride and potassium chloride content
Study NCT05817526 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BMAC/ collagen
Description: Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect
Study NCT05817526 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Autograft harvesting from chin
Description: Autograft
Study NCT05058482 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: embolism
Description: Cerebral arteriovenous malformation embolism
Study NCT05058482 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: embolism
Description: Cerebral arteriovenous malformation embolism
Study NCT05426122 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Barley rice protein concentrate shake
Description: At one out of three test days barley rice protein concentrate powder will be mixed with water to obtain a shake, representing a 20g protein load.
Study NCT05426122 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pea protein concentrate shake
Description: At one out of three test days pea protein concentrate powder will be mixed with water to obtain a shake, representing a 20g protein load.
Study NCT06070519 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CPET and related variables evaluation
Description: At the baseline visit ,CPET-related variables, echocardiographic, ECG, therapy and blood chemistry data will be collected. The baseline CPET will be repeated within 2 weeks. Patients will perform 4 follow up visits at 6, 12, 18 and 24 months after the baseline visit. At every study step, it will be performed:~* Echocardiography (LVEF)~* Blood sample (Na+, MDRD, Hb)~* Maximal ramp protocol CPET (peakVO2, VE/VCO2 slope)
Study NCT05176821 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: esomeprazole plus amoxicillin
Description: amoxicillin 750mg QID + esomeprazole 20mg QID for 14 days
Study NCT05176821 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: amoxicillin, furazolidone, bismuth potassium citrate , esomeprazole
Description: amoxicillin 1000mg BID + furazolidone 100mg BID + bismuth potassium citrate 600mg BID + esomeprazole 20mg BID for 14 days
Study NCT05426122 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whey protein concentrate shake
Description: At one out of three test days whey protein concentrate powder will be mixed with water to obtain a shake, representing a 20g protein load.
Study NCT05051813 — intervention group
Intervention type: DEVICE
Intervention: ANTERION
Description: 3 repeat measurements on each of the 3 ANTERION devices and 3 reference devices.
Study NCT06766812 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: epidural set
Description: The epidural space will be identified at either the L3-L4 or L4-L5 interspace using the loss of resistance technique with an 18 Gauge Epidural needle.A test dose of 3 mL of 2% lidocaine with epinephrine will be administered to each participant to rule out intravascular or intrathecal placement of the catheter. This ensures the proper placement of the catheter before the full dose of analgesia is administered.Following the test dose, an initial bolus of 8 mL of 0.25% bupivacaine combined with 2 μg/mL fentanyl will be administered to provide effective labor analgesia. Subsequently, maintenance Dose 0.125% 2 ml/0.5 hr
Study NCT04716959 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prepectoral Prosthetic Breast Reconstruction
Description: The prepectoral approach involves placing the tissue expander on top of the pectoralis muscle.
Study NCT04716959 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Subpectoral Prosthetic Breast Reconstruction
Description: The subpectoral approach involves placing the tissue expander under the pectoralis muscle with or without acellular dermal matrix (ADM).
Study NCT06142500 — intervention group
Intervention type: GENETIC
Group type: ACTIVE_COMPARATOR
Intervention: Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
Description: The project aims to collect biological samples of saliva from testicular cancer patients and from their first-degree family members; demographic-clinical variables will be also collected in order to draft a comprehensive panel of genes and gene modifications related to the testicular cancer, combining this survey with a very detailed descprition of this cohort of patient in terms of clinical features and quality of life
Study NCT06142500 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
Description: The project aims to collect biological samples of saliva from testicular cancer patients and from their first-degree family members; demographic-clinical variables will be also collected in order to draft a comprehensive panel of genes and gene modifications related to the testicular cancer, combining this survey with a very detailed descprition of this cohort of patient in terms of clinical features and quality of life
Study NCT05350618 — intervention group
Intervention type: OTHER
Intervention: Ultrasound evaluation
Description: A single transperineal ultrasound assessment session
Study NCT06771817 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Written Exposure Therapy
Description: WET may be an optimal treatment for pregnant or postpartum adolescents and youth with PTSD in a low resource setting. WET addresses many of the barriers above. It is delivered in just 5 sessions, with no homework, and may promote a sense of self-efficacy in adolescents and youth due to the nature of writing assignments and brief therapist involvement. It is attractive in resource-poor settings because just 10-15 min of direct therapist time per follow-up session is needed.
Study NCT06775184 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: a native video image system
Description: The visualization of the glottic structures through the SaCoVLM™ imaging system is graded as follows: Grade1: Visibility of the lateral portion of the right epiglottic fold and part of the laryngeal inlet. Grade 2: Visibility of both epiglottic folds and part of the laryngeal inlet. Grade 3: Visibility of the laryngeal inlet and part of the vocal cords. Grade 4: Visibility of the entire vocal cords.
Study NCT06775184 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a native video image system
Description: The visualization of the glottic structures through the SaCoVLM™ imaging system is graded as follows: Grade1: Visibility of the lateral portion of the right epiglottic fold and part of the laryngeal inlet. Grade 2: Visibility of both epiglottic folds and part of the laryngeal inlet. Grade 3: Visibility of the laryngeal inlet and part of the vocal cords. Grade 4: Visibility of the entire vocal cords.
Study NCT06775184 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fiberoptic bronchoscope
Description: The position of the i-Gel is checked using a fiberoptic endoscope
Study NCT06775600 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hip Replacement
Description: Total Hip Arthroplasty where the Femoral Head will be used to harvest stem cells post-extrication from the individual.
Study NCT06776445 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: minocycline combined with hydroxychloroquine
Description: Patients with rosacea were collected and randomly divided into three groups for treatment, one group was treated with minocycline combined with hydroxychloroquine, one group was treated with gabapentin 300mg Bid, and the other group was treated with gabapentin 300mg tid. Before treatment, 4 weeks after treatment, and 8 weeks after treatment, the patient's condition score was statistically analyzed, and the efficacy and difference of each group were observed
Study NCT06776445 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: gabapentin 300mg bid
Description: Patients with rosacea were collected and randomly divided into three groups for treatment, one group was treated with minocycline combined with hydroxychloroquine, one group was treated with gabapentin 300mg Bid, and the other group was treated with gabapentin 300mg tid. Before treatment, 4 weeks after treatment, and 8 weeks after treatment, the patient's condition score was statistically analyzed, and the efficacy and difference of each group were observed
Study NCT06776445 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: gabapentin 300mg tid
Description: Patients with rosacea were collected and randomly divided into three groups for treatment, one group was treated with minocycline combined with hydroxychloroquine, one group was treated with gabapentin 300mg Bid, and the other group was treated with gabapentin 300mg tid. Before treatment, 4 weeks after treatment, and 8 weeks after treatment, the patient's condition score was statistically analyzed, and the efficacy and difference of each group were observed
Study NCT03848260 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic device prototype
Description: The device prototype comprises a near-infrared light-emitting diode (SMT910, Epitex Inc, Kyoto, Japan) and receiver (PD15-22C TR8, Everlight Electronics Corporation, New Taipei City, Taiwan), a permanent electromagnetic actuator (JNP-12/12, Joint Magnetic Technology Corporation, Shenzhen, China), an iron sheet affixed to the paralytic upper eyelid, and a bio-signal acquisition module. The efficacy and safety of the device prototype was assessed using the device prototype.
Study NCT06385652 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-NB381
Description: Lei Kang from Peking University First Hospital and Bing Jia's team from the School of Basic Medical Sciences at Peking University have developed a targeted CD38 nanobody sequence using genetic engineering technology. They have optimized its structure, functionalized it with labeling, and conducted imaging and other evaluations, ultimately producing the CD38-targeted nuclear medicine small molecule diagnostic and therapeutic agent-68Ga-labeled nanobody NB381. The post-labeling quality control of the drug meets clinical trial requirements with a radiochemical purity (PCR) greater than 98% and in vitro stability not less than 90%.~Preliminary PET imaging results of 68Ga-NB381 indicate that the nanobody is primarily concentrated in the kidneys, bladder, and MM.1S and Ramos or H929 tumors (CD38+). Additionally, the cold antibody NB381 significantly inhibits the uptake of 68Ga-NB381 in tumors, confirming the high specificity of this nanobody's binding to the CD38 protein.
Study NCT06777446 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Elective Adhesionlysis
Description: See descriptions in study arms
Study NCT06777446 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Adhesion barrier
Description: At the end of adhesiolysis a barrier will be placed. The adhesion barrier to be used in laparoscopic adhesiolysis is Icodextrin 4% (Adepttm).
Study NCT06777095 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Treatment + I Taping
Description: Routine physical therapy program (10 sessions of hotpack, Transcutaneous electrical nerve stimulation (TENS), and ultrasound every day for 2 weeks) was applied. In addition to routine treatment, I taping (a total of 5 times every 3 days) was performed. Two I-shaped kinesio tapings were applied on the paraspinal muscles from the posterior superior iliac spine to the T12 level. 50% tension was applied to the area of the tapes outside the anchor points.
Study NCT06777095 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Treatment + Star Taping
Description: Routine physical therapy program (10 sessions of hotpack, Transcutaneous electrical nerve stimulation (TENS), and ultrasound every day for 2 weeks) was applied. In addition to routine treatment, star taping (a total of 5 times every 3 days) was performed. Four I tapes, one vertical, one horizontal and two at a 45° angle to the vertical tape, were applied to the point of maximum pain in the lumbar region. 25% tension was applied to the midpoint of the tapes except for the ends.
Study NCT06777095 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Routine Treatment
Description: Routine physical therapy program (10 sessions of hotpack, Transcutaneous electrical nerve stimulation (TENS), and ultrasound every day for 2 weeks) was applied. No taping was applied.
Study NCT06776055 — intervention group
Intervention type: BIOLOGICAL
Intervention: HPV-16/18 vaccine
Description: Recombinant human papillomavirus virus-like particle vaccine (Type 16 and 18 L1 Proteins, Yeast)
Study NCT04940273 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remifentanil Injection [Ultiva]
Description: Continuous infusion of remifentanil at a dose of 0.02、0.04、0.06、0.08 ug/kg/min for 30 minutes in sequence.
Study NCT05917457 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: balance coordination and strengthening training
Description: The 25 individuals who met the inclusion criteria were divided into 2 groups, including 13 in the study group and 12 in the control group.~Study group: Low vision children were given balance, coordination training and general strengthening training with sandbags for 70 minutes 3 days a week (5-minute warm-up phase, 20-minute balance training, 20-minute coordination training, 20-minute strengthening training and 5-minute cooling phase) for 8 weeks.
Study NCT05754892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Blood sample
Description: For patients with ACC : blood (30ml) sampling before surgery and every 3 months during 3 years after surgery for biobanking For patients with MPP : blood (30ml) sampling before surgery and every 6 to 12 months for MPP during 3 years after surgery for biobanking
Study NCT05754892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Urine sample
Description: For patients with ACC : urine sampling before surgery and every 3 months during 3 years after surgery for biobanking For patients with MPP : urine sampling before surgery and every 6 to 12 months for MPP during 3 years after surgery for biobanking
Study NCT06776055 — intervention group
Intervention type: BIOLOGICAL
Intervention: Placebo
Description: Placebo containing the same formulation as the active vaccine (Type 16 and 18 L1 proteins, Yeast) but without the active substance.
Study NCT05754892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Tumor sample
Description: For patients with ACC and patients with MPP : tumor sample during surgery
Study NCT05872204 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: 150 mg tablet twice daily
Study NCT05872204 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: 2.5 mg tablet once daily
Study NCT06352112 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic Floor Muscle Training
Description: PFMT consisted of both slow voluntary contractions lasting 15 seconds each (5-s contraction, 5-s hold and 5-s relaxation) and fast voluntary contractions lasting 2-s each. A set of exercises included 10 slow and 10 fast voluntary contractions. During the first week, women performed five sets of exercises a day, and the exercises were continued for eight weeks by increasing five sets each week. The exercises were performed as home exercises.