AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06201091 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Systematic simple swallowing training
Description: Systematic simple swallowing training includes the following:~Warm-up: including joint activities, chest expansion exercise, etc., totally 5 minutes.~Cognitive swallowing training: play video of food programs for five minutes. Lip training: Bounce the upper and lower lips to make a bo sound. 30-60 seconds.~Tongue training: Do the upper, lower, left, and right four-directional movements of the tongue muscle. 30-60 seconds.~Mandibular training: slowly open r mouth to the maximum, then slowly close it. 30-60 seconds.~Soft palate training: Make the sounds of g, k, and h for 1-2 minutes. Cheek puffing training: Close lips tightly and puff cheeks. 30-60 seconds. Swallowing training: We require the elderly to swallow small amounts of water intermittently and forcefully for 2-5 times.~Completing the above content in succession is called a round, and each training session includes 2-3 rounds. 2 sessions a day. Five days a week.
Study NCT06024122 — intervention group
Intervention type: OTHER
Intervention: IRM exam
Description: A non-sedated MRI scan will be performed to assess the structure and function of the children's brains
Study NCT01456923 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment with chemotherapy
Study NCT01456923 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Only chemotherapy treatment for study cohort
Description: Control patients were treated both with surgery and chemotherapy. Study patients were treated only with chemotherapy
Study NCT01456923 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: surgery
Study NCT06280677 — intervention group
Intervention type: OTHER
Intervention: AURORA-Donor
Description: Explorative study of cumulus cells gene expression in relation to the oocyte competence for good quality blastocyst formation and predictive for clinical pregnancy.
Study NCT04051801 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dose Escalation of VU319
Description: dose levels of the cohorts will be increased step wise
Study NCT04051801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dose Escalation of VU319
Description: dose levels of the cohorts will be increased step wise
Study NCT04051801 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dose Escalation of Placebo
Description: dose levels of the cohorts will be increased step wise
Study NCT04051801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dose Escalation of Placebo
Description: dose levels of the cohorts will be increased step wise
Study NCT05268289 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Iptacopan (part 1)
Description: Taken for 52 Weeks
Study NCT05268289 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Iptacopan (part 2)
Description: Taken for 52 Weeks
Study NCT05268289 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo + standard of care
Description: Taken for 52 Weeks
Study NCT05268289 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo + standard of care
Description: Taken for 52 Weeks
Study NCT05268289 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Iptacopan + placebo
Description: Taken for 52 Weeks
Study NCT04918121 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Yutiq 0.18 MG Drug Implant
Description: a sustained-release steroid insert (Yutiq)
Study NCT05718102 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Population-health management
Description: Population-health management
Study NCT05879133 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: Survey
Study NCT05879133 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fit Bit
Description: measures physical activity
Study NCT05666089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetyl cysteine
Description: intracanal medication of NAC with concentration 1 gm/ml in the form of a paste
Study NCT05666089 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium hydroxide
Description: intracanal medication of calcium hydroxide paste (metapaste)
Study NCT04920929 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hydrophilic Biomaterial
Description: PICC made out of a Hydrophilic Biomaterial
Study NCT04920929 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Thermoplastic Polyurethane
Description: PICC made out of a thermoplastic polyurethane material
Study NCT04799314 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 Inhibitor Tislelizumab maintenance therapy
Description: PD-1 Inhibitor Tislelizumab maintenance therapy
Study NCT05749887 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: salvage surgery
Description: Open/minimally invasive salvage surgery performed when cervical biopsy and/or PET/CT scan ( SUVmax ≥2.5 ) indicate patients with residual tumor intrapelvic 4-12 weeks after standard CCRT.~Surgery type:~1. No parametrial involvement, extrafascial hysterectomy;~2. There is parametrial involvement, extensive hysterectomy(Q-MC);~3. Only bladder invasion, anterior pelvic exenteration;~4. Only rectal invasion, posterior pelvic exenteration or total pelvic exenteration;~5. Invasion of bladder and rectum, total exenteration.~6. The pelvic lymph nodes are removed at the same time when 18F -FDG PET /CT indicates that the SUVmax is ≥ 2.5.
Study NCT05875597 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy exercise programme
Description: Carrying out a programme of therapeutic physical exercise for 12 weeks, twice a week for 45 minutes.
Study NCT06502262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: patient will be given 3ml (15mg) of 0.5% hyperbaric bupivacaine + 0.5 ml of normal saline intrathecally.
Study NCT06502262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: patients will be given 3ml (15mg) of 0.5%hyperbaric bupivacaine +0.5ml (25 microgram) of fentanyl intrathecally
Study NCT06502262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: patient will receive 3ml (15mg) of .05 hyperbaric bupivacaine 0.5ml(5 microgram) of diluted dexmedetomidine intrathecally
Study NCT04671368 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Artificial Intelligence
Description: The investigators will use the Artificial Intelligence Diagnostic System to review the H＆E stained slide of each patient and then report the classification of the tumor on a 10-type scale.
Study NCT04671368 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Practicing Pathologists
Description: The ordinary pathologist will review the H＆E stained slide of each patient(without additional informations such as: Immunohistochemistry et al.) and then report the classification of the tumor on a 10-type scale only bases on the slide images
Study NCT04671368 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Gold Standard
Description: Firstly, the two expert pathologist(>=10 years of experience) will review the H＆E stained slide of each patient on their own (with additional informations such as: Immunohistochemistry et al.) and then report the classification of the tumor on a 10-type scale.If they report the same opinion, that opinion will perform as the ground truth; while if their opinion clash with each other, the expert pathologist(>=15 years of experience) will get involved and the agreement of three experts will perform as the ground truth
Study NCT04791527 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind-body therapy
Description: Online yoga, meditation, behavior change tips, and nutrition tips
Study NCT05438901 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: leech therapy
Description: effects of medicinal leeches
Study NCT04909190 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Increased saline flush volume
Description: Additional flushing of the stentgraft delivery system.
Study NCT06562699 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hot Matcha brew
Description: * Hot matcha brew will be prepared in usucha (thin consistency) version-2 grams of matcha powder (Dr.Baby) mixed with 30 mL of hot water (75 ̊C). The first step will be to massage the matcha powder with a small amount of water until a smooth paste forms, then additional 50 mL of hot water will be added to dilute down the concentration. The matcha will then be vigorously shaken in a lidded jar.~* After 5 minutes of the acidic attack, participants will be instructed to swish 25 mL of matcha tea 34 times then swallow, and saliva samples will be collected (T2).~* Then saliva will be collected after 10 (T3), 20 (T4), 30 (T5), and 40 (T6) minutes.
Study NCT06562699 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Water
Description: Water (elano) at 13 ̊C swished 34 times then swallowed.
Study NCT06562699 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold matcha brew
Description: 25 mL of cold matcha brew prepared in usucha (thin consistency) version-2 grams of matcha powder (Dr.Baby) mixed with 80 mL of cold water (13 ̊C) swished 34 times then swallowed.
Study NCT04972864 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training group
Description: A regular advanced exercise program was given and followed.
Study NCT04972864 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control training group
Description: Basic exercises was given at the beginning and did the same exercises
Study NCT05815745 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pacemaker - Physiological pacing
Description: The approach for physiological pacing will be either His bundle pacing or left bundle pacing at the operator's discretion. If both of these are not achieved biventricular pacing will be performed.
Study NCT05815745 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pacemaker - Right Ventricular pacing
Description: Right ventricular pacing (apical or septal lead locations as per the implanting physicians' normal practice).
Study NCT06558162 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfetalness
Description: They will be instructed to lie on their left side and focus on the fetal movements for 15 minutes every day while the foetus is awake. They will also be instructed to monitor the character, strength and frequency of fetal movements (not to count them) and to seek medical advice if they feel any change in this pattern.~After two weeks, the pregnant women will be invited back to the organisation for a follow-up interview to check whether they have performed the practice and recorded correctly. An interview will be conducted again after four weeks.
Study NCT06558162 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sadovsky
Description: They will be asked to continue this procedure every morning, noon or evening for one month (depending on the movements of the pregnant woman and her baby, the time will be left to the pregnant woman, but it should be at the same time every day). Since the aim of the study is to increase maternal awareness rather than to determine fetal well-being, mothers will be asked to count at least 10 movements based on the count to ten and Sadovsky method, and will be asked to record the start and completion time of the movements each time. A follow-up will be made after two weeks and a final follow-up will be made after one month
Study NCT06510998 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: isometric wall exercise
Description: Each exercise session will contain 4 sets of 2-minute wall squat isometric holds with 2 minutes of rest between each set (approximately 14 minutes per session in total), and a total of 3 sessions will be arranged every week (with ideally 48 h between exercises)
Study NCT06510998 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: passive stretching
Description: A frequency-matched (3x/week) and time-matched (\~14 minutes each session) passive static stretching exercise will be used
Study NCT04919629 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Given IV
Study NCT04919629 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tumor biopsy
Study NCT04919629 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT04919629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegcetacoplan
Description: Given IV and SC
Study NCT04919629 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV
Study NCT06442631 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MyStroke
Description: MyStroke is a video-based educational platform that curates brief educational videos to inform patients and caregivers about key aspects of their stroke. Upon registering a user, information regarding the patient's stroke etiology, relevant stroke risk factors, and stroke prevention medications are used to populate educational content that is relevant to the individual. Users receive automated nudges to revisit MyStroke after hospital discharge on day 1, 3, 5, 7, and weekly thereafter.
Study NCT06345196 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: motivational interview
Description: Motivational interviewing will be conducted in four sessions and the session duration will be maximum 40 minutes. The session will be conducted individually and online once a week. For the individual interview, the appropriate day and time will be determined with the individuals with diabetes and the researcher before the first session and the sessions will continue on the same day and time every week. The researcher will remind the participant about the time of the session by calling the participant by phone one day before each session. Motivational interview sessions will be held online on the Whatsapp platform.
Study NCT06506305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FB1001
Description: Intravitreal (IVT) injection
Study NCT04730414 — intervention group
Intervention type: DRUG
Intervention: Full-spectrum hemp (0.018% THC)
Description: Topical Application
Study NCT05224011 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Boppli Infant Blood Pressure Monitor
Description: The intervention is a medical device for the non-invasive measurement of blood pressure in infants
Study NCT04919629 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05034224 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Swan-Ganz catheter placed in the coronary sinus - deflated
Description: A normal Swan-Ganz catheter will be advanced in the coronary sinus. The Balloon will be kept deflated during sham intervention. The index of microvascular resistances will be measured using the Abbott Pressure Wire X as per instructions for use durng both interventions.
Study NCT05034224 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Swan-Ganz catheter placed in the coronary sinus - inflated
Description: A normal Swan-Ganz catheter will be advanced in the coronary sinus. The Balloon will be inflated to obtain coronary sinus occlusion during the active intervention. The index of microvascular resistances will be measured using the Abbott Pressure Wire X as per instructions for use durng both interventions.
Study NCT04392440 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DIAL-SDM
Description: Communication intervention for nephrologists and coaching intervention for patients.
Study NCT04392440 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: usual care
Description: regular nephrology care
Study NCT04299282 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CanGaroo
Description: CIED ECM envelope
Study NCT06229184 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Fecal Calprotectin Test
Description: Fecal samples are taken fom obese and healthy adolescents for study
Study NCT05865327 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryoneurolysis
Description: Cryoneurolysis will be performed on the intercostal nerve associated with each fractured rib using a handheld cryoneurolysis machine (Iovera). Cryoneurolysis will consist of two 103 second cycles (includes cooling, ice ball formation and warming time) per rib fracture level. Ultrasound guidance will be used to identify appropriate rib fracture levels and to target the device tip in real time. All participants will also receive standard multimodal analgesia and ESP catheter infusion.
Study NCT05865327 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham Cryoneurolysis
Description: Participants in the control group will receive sham CN (i.e., application of device without skin puncture or activation of unit) to maintain participant blinding. All participants will also receive standard multimodal analgesia and ESP catheter infusion.
Study NCT05305430 — intervention group
Intervention type: DEVICE
Intervention: Synergy Cervical Disc System
Description: motion preservation disc
Study NCT05162664 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Pressure pain thresholds
Description: PPT will be performed firstly at the anterior tibial muscle halfway between the most superior attachment to the tibia and its tendon in the upper one third of the muscle belly (13) and secondly at the middle of the temporalis muscle (12), using a digital algometer (Wagner FPX 50) with a 1 cm2 rubber tip. The pressure algometer will apply a perpendicular increasing pressure (1kg/s) at the different test locations until the participant reports the first feeling of pain. The PPT of 4 series of ascending stimulus intensities, with an inter-stimulus interval (ISI) of 20sec between the different stimuli and an ISI of 60sec between the 2 locations, will be measured. The first stimulus is a familiarization stimulus. Afterwards the mean of the 3 subsequent stimuli will be calculated.
Study NCT05162664 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Thermal detection and pain thresholds
Description: The thermal tests will be performed unilateral at tibial anterior, thenar and the forehead, using a TSA-2 (Neuro Sensory Analyzer, MEDOC). At first cold and heat detection thresholds will be measured. The patient will be asked to indicate when they feel a change in temperature. Afterwards the patient will be asked to indicate when the stimulus becomes painful to determine the cold and heat pain thresholds. The thresholds of 4 series of stimuli will be measured. The first stimulus is a familiarization stimulus. Afterwards the mean of the 3 subsequent stimuli will be calculated for every location. The subject will push a button when the thresholds are reached. The baseline temperature will be 32°C and the stimuli will increase with 1°C/s (14).
Study NCT05162664 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Temporal summation
Description: The temporal summation will be assessed at the thenar eminence (19,20) using a ramp and hold protocol with the TSA-2 (Neuro Sensory Analyzer, MEDOC). Heat stimuli will be applied for a duration of 15sec. The stimulus temperature will increase from a baseline temperature of 35°C for 9sec at a sensitivity-adjusted rate of about 1,5°C/s until the HTP 5/10 of the thenar is reached. Afterwards the temperature will remain steady for the next 6 seconds. The maximal pain rating should be 50 ± 10 NRS. Subjects rate the pain intensity at the end of the ramp (9sec) and at the end of the hold procedure (15sec) using the NRS. Afterwards the ramp and hold aftersensations are measured. The subjects have to rate the pain intensity every 5sec for 30sec after the termination of the heat stimulus.
Study NCT05162664 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Conditioned pain modulation
Description: CPM will be assessed by comparing heat pain thresholds and pressure pain thresholds before and after giving a conditioning stimulus at a pain free distant zone by using a second thermode of the TSA-2 (17). The conditioning stimulus (HPT 4/10 (18) at the TA) will be applied for 120 seconds. The first test stimulus will be applied at the forehead 30 seconds after the start of the conditioning stimulus (17). The HPT will be measured twice with an ISI of 20 seconds. Immediately after the end of the application of the conditioning stimulus (120 seconds), the HPT at the forehead will be measured again twice, with an ISI of 20 seconds. Afterwards, there will be 10 minutes of rest to avoid bias.
Study NCT04681300 — intervention group
Intervention type: OTHER
Intervention: Skin biopsy
Description: a skin sample will be taken using a 4 mm punch biopsy in lesional skin
Study NCT04681300 — intervention group
Intervention type: OTHER
Intervention: Plastic surgery remnants
Description: healthy skin from plastic surgery interventions
Study NCT04656665 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin
Description: For patients at high risk of pre-eclampsia, start taking aspirin from 12-20 weeks of pregnancy
Study NCT04656665 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: For patients at high risk of pre-eclampsia, start taking aspirin from 12-20 weeks of pregnancy
Study NCT05664854 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nerve cuff electrodes for spatially selective vagus nerve stimulation and electrical impedance tomography
Description: Vagus nerve electrode cuffs will be placed on the exposed human vagus nerve during routine vagal nerve stimulator implantation surgery. These cuffs will then be used for spatially selective vagus nerve stimulation, with physiological readout, and electrical impedance tomography for the functional imaging of organ-specific regions in the nerve at cervical level.