AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04903210 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lifestyle modification
Description: Lifestyle modification: intake 1400-1600 kcal/day: 54% carbohydrates, 24% proteins, 22% lipids, 108 mg cholesterol, 35 g fiber; avoid smoking and alcohol consumption; performing aerobic activity 4 days per week such as 45 min on a stationary bicycle.
Study NCT04903210 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle modification
Description: Lifestyle modification: intake 1400-1600 kcal/day: 54% carbohydrates, 24% proteins, 22% lipids, 108 mg cholesterol, 35 g fiber; avoid smoking and alcohol consumption; performing aerobic activity 4 days per week such as 45 min on a stationary bicycle.
Study NCT04852367 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Focused Ultrasound
Description: Focused ultrasound targetting the tumour at subablative powers, to facilitate drug release
Study NCT05330013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: Subjects will be instructed to take dapagliflozin 10 mg once daily for 6 months (with or without food).
Study NCT05330013 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: MRI scan
Description: For subjects, depending on the subject's heart rate, base, mild, or apex short-axis slices will be acquired during the first pass of the contract (60 measurements).
Study NCT05330013 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MRI scan
Description: For subjects, depending on the subject's heart rate, base, mild, or apex short-axis slices will be acquired during the first pass of the contract (60 measurements).
Study NCT05330013 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: CMR imaging
Description: Enrolled subjects will undergo stress vasodilator and rest perfusion CMR
Study NCT05330013 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CMR imaging
Description: Enrolled subjects will undergo stress vasodilator and rest perfusion CMR
Study NCT04836468 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Tape application
Description: Magnetic Tape or Kinesiology tape will be applied randomly with both the examiner and the subjects blinded.
Study NCT04836468 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Tape application
Description: Magnetic Tape or Kinesiology tape will be applied randomly with both the examiner and the subjects blinded.
Study NCT05312593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aftoral Oral Gel
Description: Patients will use Aftoral® Oral Gel solution for the domiciliary application once a day for 15 days after the visits (no rinsing and eating for 30 minutes after gel solution application).
Study NCT05312593 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unidea Chlorhexidine mouthwash
Description: Patients will use chlorhexidine mouthwash 0,20% for the domiciliary application once a day for 15 days after the visits (no rinsing and eating for 30 minutes after mouthwash application).
Study NCT05672251 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy
Study NCT05672251 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT05672251 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo PET/CT
Study NCT05672251 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Loncastuximab Tesirine
Description: Given IV
Study NCT05672251 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mosunetuzumab
Description: Given IV
Study NCT05672251 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study NCT05605808 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercises
Description: Aerobic exercise by using the treadmill, two times per week. Its intensity was equivalent to 60-85% of each patient's maximum heart rate and lasted 20 minutes in the first week and 30 minutes in weeks 2-12.
Study NCT05605808 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercises
Description: Aerobic exercise by using the treadmill, two times per week. Its intensity was equivalent to 60-85% of each patient's maximum heart rate and lasted 20 minutes in the first week and 30 minutes in weeks 2-12.
Study NCT05605808 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet protocol
Description: A specific diet for three months is designed to boost the immune system through edible seeds and nuts which are rich in proteins, fats, fibers, minerals, and vitamins.
Study NCT05605808 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet protocol
Description: A specific diet for three months is designed to boost the immune system through edible seeds and nuts which are rich in proteins, fats, fibers, minerals, and vitamins.
Study NCT05765422 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: salivar and gum sampling
Description: Saliva will then be collected by salivary spit and a mucosal smear will be taken using a swab passed at the junction of the tooth and the gum
Study NCT04852367 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxorubicin
Description: Doxorubicin infusion
Study NCT04852367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ThermoDox
Description: ThermoDox infusion
Study NCT06000137 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dezocine
Description: dezocine for patient-controlled analgesia
Study NCT06000137 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sufentanil injection
Description: sufentanil for patient-controlled analgesia
Study NCT06000137 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flurbiprofen
Description: Flurbiprofen for patient-controlled analgesia
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inotuzumab ozogamicin
Description: By IV, given on days 12 and 19 Inotuzumab ozogamicin is approved as a single-agent in this population (patients with B-ALL) but adding it to these drug combinations has not been tested in humans
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone Pill
Description: Taken daily days 1-28 by mouth
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daunorubicin
Description: By IV, given on days 1, 8, 15, and 22
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: By IV, given on days 1, 8, 15, and 22
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Intrathecal, administered on day 1 only
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Intrathecal, administered on days 8 and 29
Study NCT03962465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pegaspargase
Description: By IV, given on day 4
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HSOG guidelines application
Description: In their practice, as regards the mode of delivery, obstetricians are encouraged to conform to the three guidelines and two consent forms published by the Hellenic Society of Obstetrics and Gynecology (HSOG). The members of the appointed Steering Committee and/or local opinion leaders will discuss and disseminate these guidelines among the professional staff in the respective maternity units, providing them with the opportunity to identify specific barriers, overcome them, and develop an implementation timetable.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Interactive workshops and courses
Description: The workshops and courses will give instruction in indications for cesarean section and clinical scenarios, physiology-based cardiotocography (CTG) interpretation, obstetric emergencies (with topics including breech delivery, trial of labor after cesarean, delivery of twins, induction and augmentation of labor), organization of the labor ward, as well as launching of regular cesarean section and CTG meetings with review of the patient notes. The workshops will last four days and will be conducted by experienced trainers. The expectation is that the obstetricians will gain very considerable knowledge and skills, which will enable them to subsequently follow these practices safely and competently.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Feedback through follow-up meetings
Description: Regular follow-up meetings with members of the steering committee and local opinion leaders throughout the intervention period will enhance compliance with the guidelines. Feedback with positive phrasing will be incorporated to meet local needs.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Robson criteria usage
Description: Obstetricians are set to a routine to enable them to use the Robson 10-group classification criteria for cesarean sections and obtain feedback on the unit's cesarean section rates monthly. They thus know which category is higher and can be reduced further.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Access to live real-time statistics
Description: Live real-time statistics provided by an online platform, on a regular basis, is expected to improve adherence, through regular feedback. Each unit will see other units' statistics by means of an anonymous reporting system. This repetition will create silent signals that will remind the participating obstetricians to remain on task.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attendance of local cesarean section meetings
Description: Local cesarean section meetings will be held weekly, in each unit. The members of the steering committee or local opinion leaders may actively participate in these meetings. Local obstetricians learn to judiciously adapt standard medical practices, thereby avoiding unnecessary medical interventions. This is a way to further enhance compliance, as during the discussions the behavior expected of the obstetricians is clearly stated by the participating opinion leaders.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attendance of local CTG interpretation meetings
Description: Local CTG interpretation meetings will be held weekly, in each unit, during which all abnormal CTG cases that led to cesarean section will be reviewed and discussed. Members of the Steering Committee or local opinion leaders may actively participate in these meetings. Obstetricians are encouraged to reflect on their medical practice through judicious physiology-based CTG interpretation.
Study NCT04504500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Reminders of proper clinical practice
Description: Effective and reliable reminders concerning optimal obstetric practice will be placed in labor wards, staff rooms, patient notes, vaginal birth packages and above theater hand washers. There will be short messages with positive phrasing regarding the benefits of vaginal birth, thus reminding birth attendants to reduce unnecessary cesarean sections. Relevant SMS (short message service) will be sent to the participating obstetricians' mobiles on a regular basis, so as to motivate them via non-verbal signals.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: HSOG guidelines implementation
Description: There will be application in daily practice of three guidelines and two consent forms pertaining to the mode of delivery published by HSOG. Obstetricians are informed on evidence-based medicine in obstetrics and provided with a structured and safe approach to labor management. The members of the appointed Steering Committee and/or local opinion leaders discuss and disseminate the guidelines among the professional staff at the respective maternity units, answer questions, and make available their knowledge and experience. Adoption of guidelines by the participating unit helps to establish clear, consistent rules that are direct and simple, and obstetricians are asked to embrace fully justified medical practice.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interactive workshops and courses training
Description: The workshops and courses will provide instruction in indications for cesarean section and case scenarios, physiology-based CTG interpretation, obstetric emergencies (with topics including breech delivery, trial of labor after cesarean, delivery of twins, induction and augmentation of labor), organization of labor ward and launching of cesarean section and CTG meetings. This type of formal training provides problem-solving strategies, using mnemonics, that are critical in emergencies and that also aid in learning and retaining the skills being taught. Functional and social skills that directly affect decision-making and effectiveness are addressed. Thus, units adopt a continuous educational procedure for their staff, enhancing their confidence when dealing with labor emergencies and redesigning labor management plans, so as to ensure high-level obstetric services.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Implementation of Robson criteria classification
Description: Use will be implemented of an online application embedded in the REDCap electronic database questionnaire with Robson 10-group classification criteria and feedback on the unit's cesarean section rates monthly, so as to know which category is higher and can be reduced further. This change in the unit's practice will introduce a new medical reporting and audit system that can detect unjustified medical procedures much more easily.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Live real-time statistics online platform
Description: Live real-time statistics provided on a regular basis by an online platform will provide feedback and essential information. Each unit will see other units' statistics using an anonymous reporting system. This information can trigger self-generative learning strategies and help obstetricians to become more effective learners.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Local cesarean section meetings
Description: Local cesarean section meetings will be held weekly in each unit. The members of the Steering Committee or local opinion leaders may actively participate in these meetings. The unit's staff can hear about both justified and unnecessary surgical procedures and draw informed conclusions as to the optimal procedure in similar cases. They will also have the opportunity to actively participate in an elaborative problem-solving discussion. These meetings when routinely conducted, provide feedback and audit resources to help improve performance and further enhance compliance.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Local CTG interpretation meetings
Description: Local CTG interpretation meetings will be held weekly, in each unit during which all abnormal CTG cases that led to cesarean section will be reviewed and discussed. Members of the Steering Committee or local opinion leaders may actively participate in these meetings offering coaching and counseling services in decision-making. Through elaborative discussion the staff will improve their knowledge and skills in correct CTG interpretation, thus preventing unnecessary interventions, such as cesarean sections.
Study NCT04504500 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Follow-up meetings
Description: Regular follow-up meetings of the participating obstetricians with members of the steering committee and local opinion leaders throughout the intervention period will enhance compliance with the guidelines. Establishment of commonly accepted practice augments the homogeneity of clinical action plans and team work in the unit.
Study NCT06313255 — intervention group
Intervention type: DRUG
Intervention: PegIFNα2b
Description: The patients receive PegIFNα2b therapy
Study NCT06313255 — intervention group
Intervention type: DRUG
Intervention: PegIFNα2b+probiotics
Description: The patients receive both PegIFNα2b and probiotics therapy
Study NCT06313255 — intervention group
Intervention type: DRUG
Intervention: Nucleoside analog
Description: The patients receive nucleoside analog therapy
Study NCT06313255 — intervention group
Intervention type: DRUG
Intervention: Nucleoside analog+probiotics
Description: The patients receive both nucleoside analog and probiotics therapy
Study NCT04325802 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone
Description: 50mg Naltrexone daily
Study NCT04325802 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Naltrexone
Description: 50mg Naltrexone daily
Study NCT04325802 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo (Mannitol) daily
Study NCT04325802 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo (Mannitol) daily
Study NCT05945784 — intervention group
Intervention type: OTHER
Intervention: Use of Rare Beauty makeup products
Description: Participants will be provided with a selection of beauty products items including foundation, concealer, blush, highlighter, and lipstick, specifically chosen for their potential accessibility features. They will have a specified trial period during which they can use the products as part of their regular beauty routines.
Study NCT05919576 — intervention group
Intervention type: DEVICE
Intervention: Near infrared imaging
Description: In the study, all volunteers are recorded with the itero Element 5D by activating the NIRI mode. The recording method does not involve ionizing radiation. 850 nm wavelength beams are used.
Study NCT06131255 — intervention group
Intervention type: DRUG
Intervention: Citalopram
Description: Patients will be administered citalopram, regardless of inclusion or non-inclusion in this study, on medical indication, as per normal clinical practice for disease management and according to the Summary of Product Characteristics (SPC). Patients will have two MRI scans done (at baseline and at 12 weeks after the start of therapy) to assess: brain volumetry, tissue amount of gray matter - GM - and white matter - WM
Study NCT05559450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blinatumomab
Description: Blinatumomab will be bridged to conventional BUCY conditioning regimen.
Study NCT05559450 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Conventional therapy
Description: Control group will be given conventional BUCY conditioning regimen.
Study NCT05732467 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: visual function training software
Description: Experimental group: If there is a refractive problem, first correct the refraction, wear corrective glasses, and then use visual function training therapy software (model: SJ-JRS2021) for treatment.
Study NCT05732467 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: occlusion therapy
Description: Control group: If there is a refractive problem, correct the refraction first, wear corrective glasses combined with occlusion therapy, and cover the fellow eye for 2 hours a day.
Study NCT05732467 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: corrective glasses
Description: corrective glasses
Study NCT05732467 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: corrective glasses
Description: corrective glasses
Study NCT05616286 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-SOS for Refugees
Description: Mindfulness-SOS for Refugees is a brief internet-based mobile-supported intervention program which is a mobile health adaptation of MBTR-R, mindfulness- and compassion-based, trauma-sensitive, and socio-culturally adapted group intervention program designed for FDPs. Mindfulness-SOS for Refugees entails 8 brief sessions and 9 mindfulness meditation practice exercises - delivered via audio recordings using participants' smartphones. The Mindfulness-SOS for Refugees intervention program is specifically designed to mitigate acute stress and related mental health symptoms among FDPs.
Study NCT05684536 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: liagsure device
Description: the vessel sealing device ( ligasure covidien ) which seals vessels by fusing the inner layers of the vessel wall, with dissection around ligament of berry and inferior thyroidal artery
Study NCT04875286 — intervention group
Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical records reviewed
Study NCT04875286 — intervention group
Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study NCT04908423 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xeomin®
Description: To discover whether injection into the upper extremity with Xeomin® triggers improvements in gait-related mobility and quality of life in adults with hemiparesis secondary to stroke.
Study NCT05219162 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Gene Profile explore
Description: The tissue and blood sample for this genetic research will be obtained from the participants at baseline(disease progression after 1L Osimertinib). Paired tissue and whole blood sample should be collected per participant for genetics during the study.
Study NCT05260047 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: IMANI
Description: For the intervention, the study will introduce and offer Medication Assisted Treatment. Those participants wishing to receive MAT will be randomized to one of two intervention IMANI + church-based telehealth MAT or IMANI + Traditional MAT + Referral and Linkage. Those who do not wish to partake of MAT services will remain in the IMANI alone.