AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05426707 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RIC
Description: RIC is a non-invasive therapy that is performed by automated pneumatic cuffs placed on bilateral arms. The RIC protocol includes five cycles of 5-min inflation to 200mmHg and 5-min deflation.
Study NCT05426707 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham-RIC
Description: The Sham-RIC protocol include five cycles of 5-min inflation to 60 mmHg and 5-min deflation by placing automated pneumatic cuffs on bilateral arms.
Study NCT05553613 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel tablet
Description: efficacy and safety of 300 mg clopidogrel followed by 75 mg once daily for 3 months will be assessed through NIHSS, mRS, duration of hospital stay, new ischemic stroke and possible adverse effects.
Study NCT05498337 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: calcium hydroxide
Description: Dental pulp medicament material
Study NCT05498337 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: MTA
Description: Dental pulp medicament material
Study NCT05498337 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Diode Laser
Description: Device used in pulp therapy
Study NCT05661461 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nab-sirolimus
Description: This is a phase 1, multi-center, open-label, dose-escalation study of nab-sirolimus in adult patients with locally advanced or metastatic solid tumors and moderate hepatic impairment or normal hepatic function.
Study NCT04972331 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Arthroscopic Partial Meniscectomy
Description: Arthroscopic partial meniscectomy was performed by three senior surgeons using two standard portals, no outflow cannula, a 5.5-mm 30° arthroscope, and a pressure-controlled irrigation system.~A standard surgical protocol was used to document possible findings in the cartilage, ligaments, synovium, and medial and lateral meniscus. In each case, surgery was limited to resection with limited debridement of the articular surface lesion, preserving as much of the meniscus as possible. Patients who underwent additional procedures, such as removal of loose bodies or subchondral drilling for any articular lesions, were excluded from this study (Figure 1). No patients underwent total meniscectomy or meniscal repair.
Study NCT04972331 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Platet- Rich-Plasma
Description: Peripheral venous blood was collected from all patients, which was then centrifuged to isolate red blood cells from the upper plasma layer. We used the Arthrex® kit APC®. The upper plasma layer was carefully collected with a serological pipette and placed in a new centrifuge tube or set aside for injection. The 5 mL remaining upper plasma layer was centrifuged again to separate platelet-poor plasma from PRP for 7 min. We activated the PRP sample by adding calcium chloride through ultraviolet irradiation, and then a 4- to 8-mL sample was used for two injections. One injection was performed intra-articularly with a supero-lateral approach. One ultrasound-guided injection was performed at the meniscal wall. Our protocol allowed us to have \< 1% blood cells and \<1% white cells in the injection.
Study NCT04972331 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Post-intervention
Description: All patients were discharged the day after surgery with no limitation of mobility but with restrictions on sports for four weeks. Interruption of work was given for 10-45 days. The same analgesics and NSAIDs were administered in both groups for two weeks. All patients then received a rehabilitation program conducted by a physiotherapist, using the same protocol as in the PRP group for four weeks.
Study NCT04972331 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post-intervention
Description: All patients were discharged the day after surgery with no limitation of mobility but with restrictions on sports for four weeks. Interruption of work was given for 10-45 days. The same analgesics and NSAIDs were administered in both groups for two weeks. All patients then received a rehabilitation program conducted by a physiotherapist, using the same protocol as in the PRP group for four weeks.
Study NCT06472180 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Glass ceramic sectional veneer
Description: partial laminate veneer
Study NCT06472180 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Glass ceramic laminate veneer
Description: Glass ceramic laminate veneer
Study NCT05263284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 8-Chloroadenosine
Description: Given IV
Study NCT05263284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT05274048 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neratinib Pill
Description: Patients will be enrolled in cohorts of 3 at each dose level of Neratinib (120 mg, 160 mg, 200 mg) daily (days 1 through 21)
Study NCT05274048 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fam-Trastuzumab Deruxtecan-Nxki (TDxD)
Description: standard dosing of TDxD (5.4mg/m2) on day 1of a 21 day treatment cycle
Study NCT04768296 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berzosertib
Description: Participants received Berzosertib at a dose of 105 milligrams per square meter (mg/m\^2 ) intravenously on Day 2 and Day 5 of each 21-day cycle until disease progression or other criteria for study intervention discontinuation are met.
Study NCT04768296 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berzosertib
Description: Participants received Berzosertib at a dose of 210 mg/m\^2 intravenously on Day 2 and Day 5 of each 21-day cycle in DL2 of safety run-in part and main part until disease progression or other criteria for study intervention discontinuation are met.
Study NCT04768296 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topotecan
Description: Participants received Topotecan at a dose of 1.25 mg/m\^2 intravenously on Days 1 through 5 of each 21-day cycle in DL1 and DL2 of safety run-in part and main part until disease progression or other criteria for study intervention discontinuation are met.
Study NCT04826341 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Berzosertib
Description: Berzosertib will be supplied as 20 mg/mL M6620 to be diluted with 5% dextrose in water solution before intravenous infusion.
Study NCT04826341 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan
Description: Sacituzumab Govitecan will be administered as an intravenous infusion once weekly on Days 1 and 8 of 21-day treatment cycles.
Study NCT06221332 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: % 0.25 bupivakain 20cc
Description: Pregnant women in group S will be given 0.25% bupivacaine, 10 cc on each side.
Study NCT06221332 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 20 cc saline
Description: Pregnant women in Group K will be given 10 cc of saline on both sides.
Study NCT06212154 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ThisCART19A
Description: Participants will receive ThisCART19A cell infusion after preconditioning, and they need to be closely monitored for 28 days following CAR-T cell infusion.
Study NCT05700539 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based cognitive behavioral therapy
Description: A ten-week treatment based on cognitive behavioral therapy for ADHD, including two mandatory modules and at least four self-selected modules (out of ten available modules). The treatment consists of reading material and exercises to be completed each week.
Study NCT06063356 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intra-articular and extra-articular Dextrose Prolotherapy injection
Description: In the prolotherapy group, 28 patients will receive intra-articular 5 cc 25% dextrose solution (4 cc 30% dextrose + 1 cc saline) and extra-articular 10 cc 15% dextrose solution (5 cc 30% dextrose + 2.5 cc saline + 2.5 cc 1% lidocaine) in 3 sessions.Extra-articular Injection: Using a sterile syringe with a 27 gauge needle tip (Dental), the points previously found and marked with US (medial collateral ligament, lateral collateral ligament, patellar ligament and adhesion sites of coronary ligaments; pes anserine and superior patellar regions) perpendicular to the surface, using peppering technique, a total of 10 cc of 15% dextrose solution (5 cc 30% dextrose + 2.5 cc saline + 2.5 cc 1% lidocaine) will be injected in small volumes (0.5cc-1cc) at each point.Injection applications will be done at weeks 0 - 3 - 6.
Study NCT06063356 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intra-articular and extra-articular Saline injection
Description: In the saline group, 28 patients are planned to receive 3 sessions of intra-articular 5 cc saline and extra-articular 10 cc lidocaine-serum physiologic solution (5 cc saline + 5 cc 1% lidocaine).Injection applications will be done at weeks 0 - 3 - 6.
Study NCT05298111 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Formulation 3
Description: Respondents were consumed 36 g of Formulation 3 containing 4.5 g of available carbohydrate dissolved in 180 ml water with study breakfast
Study NCT05298111 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Respondents were consumed 4.5 g of control containing 4.5 g of available carbohydrate dissolved in 180 ml water with study breakfast
Study NCT06536153 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Amaranth grain flat bread
Description: The recipe will be produced according to the recommended dietary allowance (RDA); based on RDA, 200 g of flat-bread (30% chickpea and 70% amaranth grain) comprised 30 mg of iron, which can satisfy 50% of RDA supposing 15-20% iron absorption (54). A prior study concluded that the acceptability was satisfactory in the community (55). Also, a study from the Hawassa University Department of Food Sciences reported that amaranth-grain flat-bread was safe for consumption for 48 hours after preparation and improved the nutritional values (56). To lower the phytate levels in the amaranth grain, home-level processing will be used. For 24 hours, amaranth grain will be soaked in water with 5 milliliters of lemon juice per 100 milliliters of water, and it will germinate for 72 hours. It will be sun-dried, roasted, and ground using a nearby electrical mill before fermented bread is made
Study NCT06536153 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Amaranth grain flat bread
Description: The recipe will be produced according to the recommended dietary allowance (RDA); based on RDA, 200 g of flat-bread (30% chickpea and 70% amaranth grain) comprised 30 mg of iron, which can satisfy 50% of RDA supposing 15-20% iron absorption (54). A prior study concluded that the acceptability was satisfactory in the community (55). Also, a study from the Hawassa University Department of Food Sciences reported that amaranth-grain flat-bread was safe for consumption for 48 hours after preparation and improved the nutritional values (56). To lower the phytate levels in the amaranth grain, home-level processing will be used. For 24 hours, amaranth grain will be soaked in water with 5 milliliters of lemon juice per 100 milliliters of water, and it will germinate for 72 hours. It will be sun-dried, roasted, and ground using a nearby electrical mill before fermented bread is made
Study NCT05560841 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: topical treatment
Description: Topical application of Nailner brush 2in1 for toenail onychomycosis
Study NCT05635552 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Dynamic retinal vessel analysis (DVA)
Description: DVA is an established, non-invasive tool to measure the responsiveness of retinal vessels to flickering light. In addition static retinal vessel parameters are recorded.
Study NCT05635552 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Optical coherence tomography (OCT)
Description: OCT is an imaging technique which applies low-coherence light to capture high resolution images from the ocular fundus.
Study NCT05402787 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual visit
Description: A virtual visit will be made to mothers whose babies are hospitalized in the neonatal intensive care unit
Study NCT05494086 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: DPLDG
Description: Dual-port laparoscopic distal gastrectomy
Study NCT05494086 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: LDG
Description: Laparoscopic distal gastrectomy
Study NCT05635552 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biochemistry and immune phenotyping
Description: Blood sample collection for clinical chemistry and isolation of PBMCs for FACS analysis.
Study NCT05537376 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SUicide Prevention by Peers Offering Recovery Tactics
Description: Following the completion of a comprehensive mental health evaluation by a licensed VA provider, which includes a suicide safety plan, if a Veteran is having active thoughts of suicide or made a suicide attempt in past three months, they may be eligible for SUPPORT. In SUPPORT, the Peer Specialist and Veteran co-create a personalized suicide-focused recovery plan (SUPPORT Plan) in flexible, 50-minute weekly encounters. The SUPPORT Plan includes modules that focus on valuing recovery, building a hope kit and daily plan, setting recovery goals, and looking ahead to enhance the Veteran's safety plan. Learning strategies are incorporated into each module to promote salience and recall of intervention material. The Peer Specialist works closely with the Veteran's treatment team and uses the most recent safety plan in the Veteran's chart to help complete the SUPPORT Plan as well as reinforce the usage of the Veteran's safety plan.
Study NCT04805762 — intervention group
Intervention type: OTHER
Intervention: Your COACH Next Door
Description: Children in the study are attending the lifestyle intervention Your COACH Next Door. A coach is supporting the child and it's family to reach their goals regarding lifestyle.
Study NCT04736082 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention Group: Infant Formula with hydrolyzed protein
Description: Infants will receive infant formula during the first 120 days of life with optional follow up until 180 days of life (intervention formula manufactured from extensively hydrolysed whey protein).
Study NCT04736082 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group: Infant Formula with intact protein
Description: Infants will receive infant formula during the first 120 days of life with optional follow up until 180 days of life (control formula manufactured from intact cow's milk protein).
Study NCT05235087 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bovine atelocollagen intradermal injection
Description: Intradermal skin test injection
Study NCT05458934 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: no intervention
Study NCT05128318 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Nissen Fundoplication, cholecystectomy
Description: Collection of adipose tissue pieces in the context of programmed abdominal surgery to treat to treat hiatal hernia, gastroesophageal reflux or vesicular lithiasis. During the surgery treatment, adipose tissue of 1-2 cm3 will be collected for the protocol by laparoscopy by the surgeon in charge of the procedures.
Study NCT05274477 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fampridine SR
Description: Fampridine SR is an inhibitor of voltage gated potassium channels and is approved in Switzerland for treatment of gait problems in patients with Multiple Sclerosis (MS).
Study NCT05274477 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: no active component
Study NCT06153264 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: neurodynamic mobilization exercise
Description: Upper extremity neurodynamic mobilization exercises and upper extremity strengthening exercises will be applied 10 repetitions a day, 3 days a week for 6 weeks.
Study NCT06153264 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strengthening exercises
Description: upper extremity strengthening exercises will be applied 10 repetitions a day, 3 days a week for 6 weeks
Study NCT05646095 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bolstering Sleep and Adjustment in Foster Environments (B-SAFE)
Description: We will adapt CBT for insomnia for children in foster care using a trauma-informed approach that considers the child's individual history, unique family environment, and child welfare policies regarding safe sleep practices.
Study NCT05646095 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Bolstering Sleep and Adjustment in Foster Environments (B-SAFE)
Description: We will adapt CBT for insomnia for children in foster care using a trauma-informed approach that considers the child's individual history, unique family environment, and child welfare policies regarding safe sleep practices.
Study NCT04862780 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLU-945
Description: Oral administration
Study NCT05635552 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Handgrip strength test
Description: Measure the maximum isometric strength of the hand and forearm muscles and their fatiguability.
Study NCT05635552 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Questionnaires (Patient reported outcomes)
Description: The questionnaires evaluate anxiety, depression, chronic fatigue, quality of life, and post-covid typical symptoms
Study NCT04862780 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: osimertinib
Description: Osimertinib tablets for oral administration
Study NCT05507463 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KBP-7072
Description: KBP-7072
Study NCT05507463 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05358197 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: yoga
Description: laughter yoga
Study NCT05356923 — intervention group
Intervention type: RADIATION
Intervention: 68Gallium FAPI PET/MR scan
Description: 68Gallium FAPI PET/MR scan
Study NCT06065267 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sequential
Description: amoxicillin 1000 mg bid ,esomprazole 20 bid for one week then levofloxacine 500 mg q.d, metraonidazoel 500 500 bid, and esomprazole 20 bid for one week
Study NCT06065267 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levofloxacin 500Mg Oral Tablet
Description: Levofloxacin 500 mg qd, amoxicillin 500 2cab bid,Tinadizole 500 bid, esomprazole 20 bid
Study NCT06210191 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intramedullary headless screw fixation
Description: fixation of fractures of metacarpals and phalanges by intramedullary headless screws
Study NCT05837585 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Air quality sensors
Description: The air quality sensors detect air quality, including temperature, humidity, carbon dioxide, respirable suspended particulates (PM10 or PM2.5), total volatile organic compounds (TVOC) and formaldehyde (HCHO), which may influence health of residences. The managers of the service unit will decide the changes of activities to improve air quality and long-term measures based on the detected air quality indexes. The care staff will follow these decisions.
Study NCT04903678 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melphalan
Description: Melphalan is performed for intrathecal chemotherapy
Study NCT05311280 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high intensity interval training plus myotherapy
Description: High intensity interval training (HIIT) has been proved its same effect on lower down body fat as moderate intensity continuous training (MICT). In addition, HIIT has the additional benefit of being a time-efficient program which can increase exercise adherence and the participants were more likely to intend to continue. Previous two studies show that HIIT could improve the severity of OSA in both obese adults and obese children.~Myotherapy: MT is composed of isotonic and isometric exercise related to oral, oropharyngeal, and respiratory exercise. Based on previous review and meta-analysis, MT can decrease not only AHI score, but also ESS score. It means that MT is beneficial to release the symptom of sudden apnea and hypopneas.
Study NCT05311280 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: home exercise plus myotherapy
Description: Home exercise: ambulation by patients themselves Myotherapy: MT is composed of isotonic and isometric exercise related to oral, oropharyngeal, and respiratory exercise. Based on previous review and meta-analysis, MT can decrease not only AHI score, but also ESS score. It means that MT is beneficial to release the symptom of sudden apnea and hypopneas.
Study NCT05320770 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: US guided TMJ intra articular injection
Description: therapeutic TMJ intra articulatr injection of blood under sonography guidance to reduce joint hyper mobility
Study NCT05894278 — intervention group
Intervention type: OTHER
Intervention: Prescription data collection
Description: Prescription data collection
Study NCT05373706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Cue Reactivity Personalized Feedback Intervention
Description: This online brief intervention provides personalized feedback using EMA data focused on alcohol cue reactivity to reduce alcohol misuse among young adults.
Study NCT06029647 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mango
Description: The participants will consume the treatment for 16 weeks, followed by a 4-week washout period.
Study NCT06029647 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: vanilla wafers
Description: vanilla wafers