AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06500078 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intermittent dietary restriction
Description: Intermittent dietary restriction will include the ILCD and ICR, which will be self-administered interventions in daily lives. The ILCD intervention will ask participants to restrict carbohydrate intake to ≤ 50 g/d on two consecutive or discontinuous days per week. The ICR intervention will ask participants to restrict caloric intake to 600 kcal/d for boys and 500 kcal/d for girls on two consecutive or discontinuous days per week.~At baseline, participants will receive face-to-face oral dietary instructions (e.g., principle of dietary restriction, sample menus, food list with macronutrients). Participants will receive the intervention booklets containing dietary advice and sample menus for diet according to the requirements of the dietary intervention.~Participants will be required to record dietary and physical activity data on a regular basis. The total intervention duration will be 12 months, including a 3-month intervention phase and a 9-month self-maintenance phase.
Study NCT06500078 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General health education
Description: General health education based on dietary and physical activity guidelines for Chinese children and adolescents, will regularly send offline and online promotional materials to participants.
Study NCT06500078 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General health education
Description: General health education based on dietary and physical activity guidelines for Chinese children and adolescents, will regularly send offline and online promotional materials to participants.
Study NCT04819360 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: VESIcare 10Mg Tablet
Description: Vesicare® 10 mg per day for 12 weeks~Vesicare 10mg 12 weeks
Study NCT04819360 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Botox 100 UNT Injection
Description: 1 injection of Botox® 100 UNT
Study NCT05772065 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CDC/NTCA guidelines only
Description: The control group will have a link to US guidelines only.
Study NCT05772065 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LTBI ASSIST and CDC/NTCA guidelines only
Description: The intervention group will have a link to both US guidelines, and the LTBI-ASSIST tool.
Study NCT06105307 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RN-SLEEP
Description: RN-SLEEP is a training program delivered via mobile application and designed to help improve the sleep of nurses who engage in shift work. RN-SLEEP aims to include training on strategies for sleeping while working shift work, basics of sleep science and physiology, behavior change components (i.e., goal setting), and components of cognitive behavioral therapy for insomnia (i.e., relaxation).
Study NCT06105307 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Habit - Educational Control
Description: Healthy habit app (i.e., exercise tracking) to act as a control arm for the RN-SLEEP intervention
Study NCT06250738 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Stress reduction program: Virtual
Description: Through mindfulness meditation and a series of carefully crafted exercises, MBSR equips individuals with powerful tools to manage stress, reduce anxiety, and enhance their overall well-being. Participants will complete 4 weekly virtual sessions covering topics like introduction to stress and its consequences, awareness of sensations, and thoughts, mindful eating, and mindful walking.
Study NCT06250738 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home exercises
Description: Following each virtual session, participants will be given home exercises like practicing awareness of breathing, awareness of thoughts, and awareness of eating.
Study NCT06123767 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CAS + Intravascular measuring the pressure gradient
Description: Measurements taken during the procedure during CAS~* placement of a FFR- micro catheter on the neuroprotection wire and taking a measurement before the stenosis and in the internal carotid artery above the stenosis~* reading the pressure gradient after obtaining a stable value (a minimum of 5 cardiac cycles)~  * the study of intravascular pressure measurements will be performed using a special micro catheter
Study NCT06123767 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CAS (standard)
Description: Animation of blood pressure measurements on the FFR console without actual measurement in carotid artery (blinding of the study to the patient) during CAS procedure.
Study NCT06123767 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CAS (standard)
Description: Animation of blood pressure measurements on the FFR console without actual measurement in carotid artery (blinding of the study to the patient) during CAS procedure.
Study NCT06123767 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Doppler ultrasonound of cephalic arteries
Description: non-invasive assessment of carotid stenosis before surgery and assessment of results after CAS (3 and 12 months after CAS)
Study NCT06123767 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Doppler ultrasonound of cephalic arteries
Description: non-invasive assessment of carotid stenosis before surgery and assessment of results after CAS (3 and 12 months after CAS)
Study NCT06123767 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Angio-CT of the neck and head
Description: Non-invasive pre-operative assessment and post-CAS result (3 months after)
Study NCT06123767 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Angio-CT of the neck and head
Description: Non-invasive pre-operative assessment and post-CAS result (3 months after)
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Otolaryngological examination
Description: Hearing and balance tests (before and after CAS) - prospective follow-up
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Otolaryngological examination
Description: Hearing and balance tests (before and after CAS) - prospective follow-up
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Psychological examination
Description: psychological examination with questionnaires (before and after CAS) - prospective follow-up
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychological examination
Description: psychological examination with questionnaires (before and after CAS) - prospective follow-up
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neurological examination
Description: neurological examination with questionnaires (before and after CAS) - prospective follow-up
Study NCT06090500 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cryotherapy
Description: preoperative submucosal infiltration injection of cold saline solution (2-5 degrees Celsius)
Study NCT06090500 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Diclofenac sodium
Description: preoperative submucosal infiltration injection of Diclofenac sodium (25mg/ml)
Study NCT06090500 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone sodium phosphate
Description: preoperative submucosal infiltration injection of dexamethasone sodium phosphate (4mg/ml)
Study NCT06123767 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurological examination
Description: neurological examination with questionnaires (before and after CAS) - prospective follow-up
Study NCT06426992 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microwave ablation
Description: Following the existing procedure of our institute, we aim to treat the tumor by applying up to 150W of microwaves within the tumor using a StarWave microwave generator and a 13-gauge antenna under fusion ultrasound guidance. If necessary, the antenna is reinserted 1-2 times to create sufficient ablation lesions until an echogenic band of 5-10mm is formed around the tumor and its periphery, implementing overlapping microwave ablation (MWA). Afterward, the antenna is removed while applying microwave energy to prevent bleeding.
Study NCT06123767 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: MR cerebral perfusion
Description: Assessment of the cerebral perfusion alterations using DSC (dynamic susceptibility contrast) MR perfusion, before and after CAS (after 3 months):~Parametric maps of cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), and mean transit time (MTT) will be generated and used for the qualitative and quantitative analyses of the following perfusion parameters:~* cerebral blood volume (CBV) value in ml/100ml;~* cerebral blood flow (CBF) value in ml/100ml/min;~* mean transit time (MTT) value in seconds~* time to peak (TTP) value in seconds
Study NCT06123767 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MR cerebral perfusion
Description: Assessment of the cerebral perfusion alterations using DSC (dynamic susceptibility contrast) MR perfusion, before and after CAS (after 3 months):~Parametric maps of cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), and mean transit time (MTT) will be generated and used for the qualitative and quantitative analyses of the following perfusion parameters:~* cerebral blood volume (CBV) value in ml/100ml;~* cerebral blood flow (CBF) value in ml/100ml/min;~* mean transit time (MTT) value in seconds~* time to peak (TTP) value in seconds
Study NCT06292728 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ENDOPLY System
Description: One endoscopic procedure where the ENDOPLY System is used for endoscopic gastric plication.
Study NCT06157502 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Shuxuening Injection
Description: Receiving 20 ml Shuxuening injection plus 250ml 0.9% sodium chloride injection, intravenous drip once a day, for 10-14 days
Study NCT06157502 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Receiving 20 ml placebo Shuxuening injection plus 250ml 0.9% sodium chloride injection, intravenous drip once a day, for 10-14 days.
Study NCT05712226 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Sleepiz One+
Description: In this study Sleepiz One+ will measure heart rate and respiration rate of a participant sitting or lying in different positions (right and left side, back, abdomen) on a bed. The recording will take around 35 minutes.
Study NCT06194903 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: isopropyl alcohol wipes
Description: cellphones will be sanitised with isopropyl alcohol wipes and total bacterial load will be assessed immediately before sanitation, immediately after sanitation and 3 hours after sanitation.
Study NCT06194903 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: UVC box
Description: cellphones will be sanitised in a UVC box and total bacterial load will be assessed immediately before sanitation, immediately after sanitation and 3 hours after sanitation.
Study NCT05464511 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.
Description: Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.
Study NCT03887481 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-definition active tDCS (HD-tDCS) + Repeat After Me (RAM) Treatment
Description: Device: Active HD-tDCS \& Repeat After Me (RAM) Treatment~Stimulation will be delivered by a battery-driven constant current stimulator. Electrical current will be administered to left supramarginal gyrus (L_SMG). The stimulation will be delivered at an intensity of 2 milliamperes (mA) (estimated current density 0.04 mA/cm2; estimated total charge 0.048 Coulombs/cm2) in a ramp-like fashion for a maximum of 20 minutes.~Participants will receive RAM consisting of word span repetition span (increasing length, with/without response delay). Span tasks will be manipulated in terms of list length (single words, pair, triplets) and response delay (1 sec, 5 sec). Each list will consist of 10 spans. During each trial, participants will be asked to repeat words in the span after a response delay.
Study NCT03887481 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham + Repeat After Me (RAM) Treatment
Description: Device: Sham Current will be administered in a ramp-like fashion but after the ramping phase the intensity will drop to 0 mA. Current under the Sham condition will last for a maximum of 30 seconds.~Participants will receive RAM consisting of word span repetition span (increasing length, with/without response delay). Span tasks will be manipulated in terms of list length (single words, pair, triplets) and response delay (1 sec, 5 sec). Each list will consist of 10 spans. During each trial, participants will be asked to repeat words in the span after a response delay.
Study NCT06047197 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RC19D2 cell injection
Description: The functional component of RC19D2 cell injection is T cells that have been genetically modified to express anti CD19 chimeric antigen receptors.
Study NCT05874258 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-PL training + Real-tES(tDCS)
Description: PLtraining : around 40mins, tDCS: 20mins
Study NCT05874258 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real-PL training + Sham-tES (tDCS)
Description: PL training : around 40mins, tDCS: 20mins
Study NCT05874258 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo-PL training + Sham-tES (tDCS)
Description: PL training : around 40mins, tDCS: 20mins
Study NCT06394128 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cangpo Liujun Prescription
Description: Based on the diagnostic criteria of spleen deficiency and dampness excess syndrome, Cangpo Liujun Prescription could be used to treat cancer-related fatigue in patients with advanced colorectal cancer undergoing second-line chemotherapy.
Study NCT06394128 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cangpo Liujun Prescription
Description: Based on the diagnostic criteria of spleen deficiency and dampness excess syndrome, Cangpo Liujun Prescription could be used to treat cancer-related fatigue in patients with advanced colorectal cancer undergoing second-line chemotherapy.
Study NCT05771519 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIV disclosure intervention
Description: This will be a biobehavioral intervention focused on helping men with HIV to disclose their HIV status to a personal confidant inclusive with specific focus on sexual partners.
Study NCT06052384 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard pain management combined with sleep disorder management
Description: Standard pain management combined with sleep disorder management at M3, M6, and M12
Study NCT05067075 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blinded CGM
Description: CGM that records blood glucose but is not visible to patient or provider in real-time
Study NCT05501509 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Coracoclavicular fixation with acromioclavicular stabilization for the management of an unstable acromiclavicular luxation
Description: Using a 3-hole third plate and high resistance sutures across the acromioclavicular joint to achieve horizontal and vertical stability of the joint
Study NCT05327790 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lyophilized fecal microbiota (LFMT)
Description: vedolizumab or ustekinumab + FMT vs placebo
Study NCT05327790 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06427954 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Digital Health App
Description: access to a digital health app
Study NCT05501509 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coracoclavicular fixation for the management of an unstable acromiclavicular luxation
Description: Isolated coracoclavicular repair using a 3 hole third plate.
Study NCT06154772 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Color Therapy
Description: Color therapy will be applied to the body chakras for 10-15 minutes with colored fabrics, color therapy with water and colored light lamp.
Study NCT06534333 — intervention group
Intervention type: OTHER
Intervention: Ultrasonography
Description: musculoskeletal ultrasonography
Study NCT06009159 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Vagus Nerve Stimulation
Description: 30 minutes stimulation, twice per day for 4 weeks
Study NCT05431348 — intervention group
Intervention type: DEVICE
Intervention: Smartwatch
Description: Patients will wear the smartwatch during treatment which measures, activity, steps, sleep and heartrate
Study NCT05768503 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental drug
Description: The treatment option for the chidamide + sintilimab + bevacizumab is 200 mg of sintilimab IV Drip Q3W, 30 mg of chidamide PO BIW, and bevacizumab 7.5 mg/kg IV Drip Q3W until loss of clinical benefit or development of intolerable toxicity (whichever occurs first), with a maximum treatment duration of 2 years.
Study NCT05768503 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Control Rx
Description: The treatment option for the standard second-line FOLFIRI + bevacizumab therapy group is bevacizumab 5 mg/kg IV Drip Q2W, irinotecan 180 mg/m2 IV Drip Q2W, calcium folinate 400 mg/m2 IV Q2W or calcium levofolinate 200 mg/m2 IV Drip Q2W, 5-fluorouracil 400 mg/m2 IV +2400 mg/m2 CIV (infusion 46-48 hr) Q2W until loss of clinical benefit or development of intolerable toxicity (whichever occurs first), with a maximum treatment duration of 2 years.
Study NCT04401007 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Erector Spinae Plane Block with 1.5% lidocaine
Description: Erector spinae plane (ESP) block is a new regional nerve block technique that involves a percutaneous injection of local anesthetic as a bolus through a needle or catheter into the fascial plane between the erector spinae muscle and the transverse processes in the upper or mid back.
Study NCT06071871 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glofitamab
Description: Glofitamab is given intravenously at a dose of 2.5mg over 4 hours on Cycle 1 Day 8. Patients need to stay in hospital for 24 hours.~Glofitamab is given intravenously at a dose of 10mg over 2 hours on Cycle 1 Day 15. (Patients may need to stay in hospital for 24 hours.) Glofitamab is given intravenously at a dose of 30mg over 2 hours on Day 1 of Cycles 2-12 (as relevant).
Study NCT05431348 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Serum Cortisol
Description: Level of cortisol in serum will be determined
Study NCT05431348 — intervention group
Intervention type: OTHER
Intervention: Questionnaires
Description: Patients are asked to fill in patient reported outcomes (PROMS) and specific questions on stress, exercise and fatigue (QSC-R23, IPAQ-SF, MVI-20)
Study NCT05307250 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE
Description: In addition to the BSOC, ALHIV and their caregivers will participate in a family strengthening intervention plus a family economic empowerment intervention.~MFG is an evidence-based family-centered, group-delivered, evidence-informed, strength-based 10-session (weekly) intervention for children whose families struggle with poverty. Six additional sessions covering HIV stigma stigma-related issues will be added.~ALHIV will receive a YDA with a 1:1 matched savings program at a financial institution accredited by the Bank of Uganda. Each YDA will be opened in the name of the adolescent, with their primary caregiver as a co-signer, until the adolescent turns 18 years. The account will then be matched with money from the program on 1:1 rate.
Study NCT06071871 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Polatuzumab vedotin
Description: Polatuzumab is given intravenously at a dose of 1.8mg/kg on Cycle 1 Day 2, and then Day 1 of Cycle 2-Cycle 6.
Study NCT05307250 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE plus Group-based stigma reduction for educators (GED-HIVSR).
Description: In addition to BSOC and MFG-HIVSR+FEE, ALHIV in this arm will receive the school-level HIV stigma reduction intervention targeting teachers, school nurses, matrons, and administrators (headteachers, director of studies) in their schools. GED-HIVSR seeks to impart educators in the intervention schools with HIV related knowledge, provide a safe space for educators to explore their personal values and bias that may promote or hinder their role of supportive individuals and systems for ALHIV, and empower them with knowledge and skills to act as change agents within their schools.
Study NCT05307250 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Bolstered Standard of Care (BSOC)
Description: All participants (in control and treatment arms) will receive medical and psychosocial support as part of the BSOC. 1) Medical SOC: All public clinics, including our study sites, follow procedures for pediatric ART initiation and monitoring, as outlined in the National Department of Health Guidelines for pediatric HIV care in Uganda. Specifically, immediately after initiation, or if clinically unstable, ALHIV are seen more frequently (weekly to monthly). Laboratory data (VL and CD4 counts) are collected every six months until the patient is stabilized and then annually, using the National Health Laboratory Service standardized protocol. A
Study NCT06071871 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Obinutuzumab pre-treatment is given intravenously at a dose of 1g on Cycle 1 Day 1.