AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04561778 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Biventricular Pacing
Description: Subjects enrolled in the study will receive a permanent CIED (CRT-pacemaker or CRT-defibrillator) as clinically indicated. Subjects randomized to Biventricular pacing will undergo left ventricular lead placement in the coronary sinus venous branches.
Study NCT05765201 — intervention group
Intervention type: OTHER
Intervention: High IOP
Description: Prospective, single-surgeon, randomized, paired-eye study; patients undergoing sequential, uncomplicated bilateral phacoemulsification using Active Sentry handpiece® with intraocular IOP ≤ 28mmHg (low IOP) in one eye and with IOP ≥ 60mmHg (high IOP) in the other eye
Study NCT05765201 — intervention group
Intervention type: OTHER
Intervention: Low IOP
Description: Prospective, single-surgeon, randomized, paired-eye study; patients undergoing sequential, uncomplicated bilateral phacoemulsification using Active Sentry handpiece® with intraocular IOP ≤ 28mmHg (low IOP) in one eye and with IOP ≥ 60mmHg (high IOP) in the other eye
Study NCT06265519 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Holmium laser enucleation of the prostate
Description: Holmium laser enucleation of the prostate is a minimally invasive procedure that uses pulses of laser beam to remove tissue from the inside of the prostate, which surrounds the urethra (the tube leading from the bladder to the urinary opening) in patients with BPH
Study NCT05388084 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Male peer engagement
Description: Male partners of women randomized to the intervention arm will receive a phone call from the male peer to encourage them to test for HIV at the clinic. Male peer fathers will offer to meet men at the clinic and guide them through the process of HIV testing. Men who are not willing/able to attend the clinic for HIV testing will be offered testing in a private and confidential location in the community; the peer male counselor meet men and offer to assist them through the process of using and interpreting an oral HIVST. Men who are not interested in testing with the peer father will be offered the HIVST kit to take home. Peer fathers will obtain men's consent to participate in the study.
Study NCT05388084 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SOC and delayed intervention
Description: Females receive standard of care invitation letter to provide to their partner for fast-track HIV testing and male peer father phone calls after a 3 month delay.
Study NCT04862975 — intervention group
Intervention type: DRUG
Intervention: Dolutegravir
Description: Dolutegravir will be administered in accordance with local SOC as prescribed by the lactating woman's healthcare provider. Not prescribed for this study.
Study NCT04862975 — intervention group
Intervention type: DRUG
Intervention: Lamivudine
Description: Lamivudine will be administered in accordance with local SOC as prescribed by the lactating woman's healthcare provider. Not prescribed for this study.
Study NCT04862975 — intervention group
Intervention type: DRUG
Intervention: Emtricitabine
Description: Emtricitabine will be administered in accordance with local SOC as prescribed by the lactating woman's healthcare provider. Not prescribed for this study.
Study NCT04862975 — intervention group
Intervention type: DRUG
Intervention: Tenofovir Disoproxil Fumarate
Description: Tenofovir Disoproxil Fumarate will be administered in accordance with local SOC as prescribed by the lactating woman's healthcare provider. Not prescribed for this study.
Study NCT04456400 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multispectral Optoacoustic Tomography (MSOT)
Description: cMSOT-2 system is indicated for measurement of the Multispectral Optoacoustic Tomography (MSOT) values in the bowel wall of patients with an established diagnosis of inflammatory bowel disease (IBD), specifically Crohn's Disease (CD) and Ulcerative Colitis (UC). The MSOT values provided may be used as an aid to the assessment of inflammatory disease activity in the bowel wall.
Study NCT05765071 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Botulinum toxin A
Description: Botulinum injections will be prepared by diluting 100 units of botulinum toxin A with 5.0mL of saline (20.0U/mL). A total of 100 units (5.0mL) of botulinum toxin A will be injected into the tibialis anterior, peroneus longus and peroneus brevis muscles of the affected leg. Under ultrasound guidance, the injectant will be deposited at two sites in each muscle near the motor points.
Study NCT05765071 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: A total of 5.0mL of normal saline will be injected into the tibialis anterior, peroneus longus and peroneus brevis muscles of the affected leg. Under ultrasound guidance, the injectant will be deposited at two sites in each muscle near the motor points.
Study NCT06101888 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TaurusTrio™ Heart Valve System
Description: The TaurusTrio™ Heart Valve System contains the following sub-components: a prosthetic transcatheter porcine pericardial aortic valve, 20Fr Introducer Sheath System, transfemoral Delivery Catheter, and Loading Tool.
Study NCT05961189 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azithromycin
Description: Standard of care, 5 days of drug per manufacturer's instructions.
Study NCT04766190 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Group 2: The DISCO App
Description: Patients will receive an individually-tailorable cancer treatment cost education and communication intervention delivered on an iPad just prior to meeting with their oncologist.
Study NCT04766190 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Group 1: Usual Care
Description: Patients randomized to this arm will receive usual care.
Study NCT04766190 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Group 3: The DISCO App + Booster
Description: Patients will receive an individually-tailorable cancer treatment cost education and communication intervention delivered on an iPad just prior to meeting with their oncologist. Then, 2 months later they will receive an intervention booster in the form of an individually-tailored email to remind patients of the contents of the intervention.
Study NCT04831879 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GONDOLA AMPS
Description: The Gondola device is composed of two units, one per foot, each having two motors that activate rounded stimulation tips that interact with the target points. It delivers mechanical, pressure-based stimulations, sequentially in each of the four points, for the duration of 6 seconds per point. This treatment cycle is repeated 4 times, for an overall treatment duration of less than 2 minutes
Study NCT05393089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGN-190584
Description: Eye drops
Study NCT05393089 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Eye drops
Study NCT06508892 — intervention group
Intervention type: BEHAVIORAL
Intervention: risk of fall
Description: Gather information that will assist in determining risk of fall. The researchers will ask the subjects to perform several motor tests and study-related questionnaires.
Study NCT05368155 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief ACT for Pelvic Pain
Description: The Brief ACT for Pelvic Pain treatment will include three weekly, 90-minute group sessions that teach Veterans new ways to respond to difficult thoughts and emotions related to pain (Acceptance and Mindfulness Training) and encourage behavioral (re)engagement in meaningful life activities (Behavioral Change Training). The overall goal is to cultivate psychological flexibility by helping Veterans learn to respond to life events in ways which do not exacerbate difficulties or restrict engagement in meaningful activities. Workshop content is integrated with education on pelvic pain (its diagnostic criteria, etiology, and associated health outcomes) to increase alignment of the treatment with patient needs.
Study NCT06445400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BL-M07D1
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study NCT06445400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pertuzumab
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study NCT06445400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Administration by intravenous infusion for a cycle of 3 weeks.
Study NCT06413953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3107 Tablets
Description: TQB3107 tablets is protein inhibitor that inhibit tumor cell proliferation, and induce apoptosis, thereby exerting anti-tumor effects.
Study NCT03653000 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound guided brachial plexus blockade
Description: Ultrasound probe disposed on the shoulder, on the deltoid muscle. in plane puncture toward the brachial artery and injection of local anaesthetics around the brachial artery
Study NCT03653000 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: local anaesthetic injection
Description: Local anesthetic injection (ropivacaine) at this new site
Study NCT04906265 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intervention
Description: The intervention comprises of standard rehabilitation and continuous measures of body positions and movements 24 hour a day with an IMU. Standard rehabilitation comprises of home-visits by a PT, where an individualized rehabilitation plan is outlined together with the patient. The plan includes individually tailored functional exercises. The plan also includes individually tailored walking exercises, indoor and outdoor when possible. At each home visit, the PT provides feedback to the participant based on the data from the IMU, i.e. body positions (time spent in sitting, standing, lying down) and body movements (steps per day, step length, walking speed, sideway deviation during walking)
Study NCT04906265 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Standard rehabiliation
Study NCT05068011 — intervention group
Intervention type: DEVICE
Intervention: Spinal Cord Stimulation
Description: differential target multiplexed stimulation
Study NCT06224296 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DFPP
Description: One session of blood purification using DFPP to remove inflammatory cytokines in peripheral blood.
Study NCT06224296 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DFPP
Description: One session of blood purification using DFPP to remove lipids in peripheral blood.
Study NCT06224296 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DFPP
Description: One session of blood purification using DFPP to remove toxic metal ions.
Study NCT05194033 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics daily
Description: Probiotics 1 time/day for 7 consecutive days
Study NCT05194033 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo daily
Description: Placebo 1 time/day for 7 consecutive days
Study NCT06371586 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin paclitaxel+SOX+BEV+ PD-1 monoclonal antibody therapy
Description: Albumin paclitaxel+SOX+BEV bi weekly neoadjuvant therapy for 6 cycles, with PD-1 monoclonal antibody therapy interspersed for 4 cycles. Review CT and gastroscopy every 3 cycles to evaluate the therapeutic effect. Patients who have been evaluated as effective after 6 cycles of treatment may consider surgery; Or continue the two-week regimen of albumin paclitaxel+bevacizumab for 3 cycles, while PD-1 monoclonal antibody for 2 cycles. Afterwards, the therapeutic effect will be evaluated, and surgery, radiotherapy, or maintenance medication treatment will be determined based on the therapeutic effect. Surgical patients begin adjuvant treatment 1-2 months after surgery based on the curative and pathological results of the surgery. Those who fail to evaluate during neoadjuvant therapy will undergo surgery or radiation therapy, or switch to a second-line systemic treatment plan.
Study NCT05652803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: bibliotherapy-based psychoeducation program
Description: In this study, the researcher aimed to gain awareness, skills and attitudes in order to help the participants reduce the negative consequences of depression and hopelessness. Based on the general purpose, a separate target has been established for each session of both intervention types. For bibliotherapy-based psychoeducation, story texts compatible with the goals were added to each session, and the psychoeducation part was supported by bibliotherapy. Considering the ability of the elderly to attend the training regularly, their attention and coordination, it was decided that the study would consist of 6 sessions and each session would be 60 minutes on average.
Study NCT05652803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: psychoeducation program
Description: The General Purpose of the Psychoeducation Program for Reducing Depression and Hopelessness: To help the participants gain awareness, skills and attitudes in order to help them reduce their depression and hopelessness levels.
Study NCT05420831 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal
Description: Sacrospinous hysteropexy using the synthetic mesh
Study NCT05420831 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic
Description: Laparoscopic Sacrohysteropexy
Study NCT02441439 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Iron sucrose 200 mg
Description: I.V Iron sucrose 200 mg 2-3 times per week. Each time for 20-30 minutes
Study NCT02441439 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Iron sucrose 500 mg
Description: I.V Iron sucrose 500 mg once per week. Each time for 3.5 hours
Study NCT05440604 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fortified milk
Description: Commercially available milk-based fortified beverage that has an updated profile of key micronutrients along with appropriate levels of protein and other macro- and micro- nutrients, in accordance with global and local nutritional recommendations
Study NCT05048615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax 100 MG
Description: Patients will receive oral Venetoclax at a fixed dose of 100mg/day from day 1 to day 21 per cycle for a maximum of 2 cycles.
Study NCT05048615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole capsule
Description: Patients will receive oral itraconazole at a dose of 100 mg every 12 hours from day 1 to day 21.
Study NCT05470270 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxycarbamide
Description: Single administration of the new dispersible form of hydroxycarbamide at the usual dose in children with sickle cell disease who are already treated with the current form of hydroxycarbamide.
Study NCT06103643 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Using High Reality Simulator
Description: Using High Reality Simulator will perform emergency breech birth.
Study NCT06103643 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Using High Reality Simulator
Description: Using High Reality Simulator will perform emergency breech birth.
Study NCT06240429 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Collagen
Description: Daily doses of 10 g collagen peptide supplementation
Study NCT04992754 — intervention group
Intervention type: BEHAVIORAL
Intervention: psychotherapy, lifestyle counseling
Description: psychotherapy, lifestyle counseling
Study NCT05091957 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Community Support Worker
Description: structured review of participant income supports with a trained CSW, to identify financial needs and benefits for which the family is eligible, including assessment of income and food security, affordability of medications, housing and energy insecurity, and dental care. The visits will be conducted in person, by telephone or by videoconferencing, according to participant preference and to ensure adherence to COVID-19 pandemic-related criteria.
Study NCT05091957 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants in both groups will receive a written summary of available resources
Study NCT05224843 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
Description: Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES) screening tool.
Study NCT04432792 — intervention group
Intervention type: OTHER
Intervention: Questionnaire
Description: Study survey participants will be administered 3 online surveys.
Study NCT04872023 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood and bone marrow sampling
Description: Blood and bone marrow sampling
Study NCT05121389 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: normal saline
Description: Normal saline is injected intravenously, using a infusion rate control device to control the drip rate.
Study NCT05121389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: normal saline
Description: Normal saline is injected intravenously, using a infusion rate control device to control the drip rate.
Study NCT04897204 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Catheter ablation and left atrial appendage occlusion
Description: The patients underwent routine pulmonary vein isolation and linear ablation and left atrial appendage occlusion.
Study NCT04897204 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Additional left atrial appendage electrical isolation combined with catheter ablation and left atrial appendage occlusion
Description: These patients underwent routine pulmonary vein isolation and linear ablation and left atrial appendage occlusion, combined with additional left atrial appendage occlusion.
Study NCT05244369 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Only TENS
Description: Rehabilitation program consisting of joint range of motion, stretching and strengthening exercises for 30 minutes, 5 days a week for only 4 weeks, and application of transcutaneous electrical nerve stimulation (TENS) to the tip of the stump
Study NCT05244369 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Acupuncture+TENS
Description: acupuncture application twice a week - a total of 8 sessions, rehabilitation program consisting of exercises 5 days a week for 4 weeks and transcutaneous electrical nerve stimulation (TENS) to the stump tip.
Study NCT05205070 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Rosnilimab
Description: humanized monoclonal antibody
Study NCT05205070 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo solution
Study NCT03687008 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Computer Based Intervention
Description: 25 sessions \[each 30-45 minutes, 5 days a week / for 5 weeks\], supervised by trained coaches
Study NCT05048615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine Injection
Description: Patients will receive a maximum of two cycles of daily subcutaneous Azacitidine at a dose of 75 mg/m2 (maximum 100 mg) from day 1 to day 7.
Study NCT05291923 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study NCT02217670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin 1000 mg granules
Study NCT02217670 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin 1000 mg film-coated tablets
Study NCT05176925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Tislelizumab 200mg IV D1, Q3W
Study NCT05176925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sitravatinib
Description: The starting dose of sitravatinib in this study is 70 mg, oral once daily. After receiving 2 cycles of starting dose at 70 mg once daily with sitravatinib, if patients were tolerated well with study treatment (without AEs definitely related to sitravatinib nor TRAEs leading to sitravatinib dose reduction and interruption), it is recommended to escalate sitravatinib dose to 100 mg once daily at the discretion of the investigators after discussion with patients.
Study NCT05394454 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bladder stimulation technique
Description: The bladder stimulation technique consists of two consecutive maneuvers. In the first maneuver, the bladder is stimulated by tapping the suprapubic region for 30 seconds at a frequency of 100 touches per minute. In the second maneuver, circular massage is applied to the paravertebral region for 30 seconds. The two stimulation maneuvers will be repeated alternately for 3 minutes (180 seconds) until micturition begins.
Study NCT05626075 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Using Oculus Pentacam® which is s a rotating Scheimpflug camera. The rotational measuring procedure generates Scheimpflug images in three dimensions.
Description: Scheimpflug imaging attains a wide and high depth-of-focus , providing sharp images that include information from an anterior corneal surface through to the posterior crystalline capsule
Study NCT05647720 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Distalization combined with upper third molars extraction
Description: After surgical extraction of unerupted upper third molars, the maxillary first molars were distalized using a labial bow with two soldered crimpable hooks distal to the upper lateral incisors. The labial bow fitted in the flying tube of the upper first molar bands. It was anchored bilaterally to the infra-zygomatic mini-implant by closed coil spring that applied a force of 300gm on each side