AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06575296 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electronic Health Record Review
Description: Ancillary studies
Study NCT06575296 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT06342063 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Blood Flow Restriction Therapy
Description: Patients wear a personalized tourniquet pressure system on their involved thigh while they perform a series of leg press machine exercises. This tourniquet is inflated.
Study NCT06575296 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06575296 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Revumenib
Description: Given PO
Study NCT05955586 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPR720
Description: SPR720 1000 mg (250 mg\*4 capsules) will be administered orally.
Study NCT05176431 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ESWT (wave type: focused)
Description: Extracorporeal Shock Wave Therapy, device: Electronica, Pagani, Italy
Study NCT05176431 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ESWT (wave type: radial)
Description: Extracorporeal shock wave therapy, device: Electronica, Pagani, Italy
Study NCT05176431 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: ESWT (wave type: sham)
Description: Extracorporeal shock wave therapy, device: Electronica, Pagani, Italy
Study NCT06473493 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alverine
Description: 180 mg/day (1 capsule orally, 3 times a day), taken continuously for 24 weeks
Study NCT05346913 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-delivered Cognitive Behavioural Therapy(ICBT)
Description: ICBT provides online structured self-help modules over several months based on the principles of CBT in combination with weekly guidance through emails and telephone calls. The course comprises 6 online lessons that provide psychoeducation about: 1) symptom identification and the cognitive behavioural model; 2) thought monitoring and challenging; 3) de-arousal strategies and pleasant activity scheduling; 4) graduated exposure/pacing; 5) memory and attention; and 6) relapse prevention. Participants will also have the opportunity to ask any questions regarding the content of the program materials and will receive a response from their Guide within 48-72 hours. Guide will spend \~15 mins. per week/per participant. All Guides have completed a university program (psychology or social work) and are registered clinicians or students working under supervision of a registered clinician.
Study NCT06342063 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Blood Flow Restriction Therapy Sham
Description: Patients wear a personalized tourniquet pressure system on their involved thigh while they perform a series of leg press machine exercises. This tourniquet is not inflated.
Study NCT05067101 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Capsule Sparing Cystectomy (CSC)
Description: Adopt endoscopic enucleation technology to preserve the prostate capsule and part of the urinary control support structure to help restore urinary control and erectile functions
Study NCT05516641 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Soluble Corn Fiber
Description: once daily additive to diet
Study NCT05743049 — intervention group
Intervention type: OTHER
Intervention: Obtaining blood for analysis of various circulating biomarkers
Description: 4 tbsp of blood in a 1-week period, occurring no more frequently than 4 times in an 8-week period
Study NCT06468696 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suturing the cervical linea alba during endoscopic thyroid surgery.
Description: Suturing the cervical linea alba during endoscopic thyroid surgery.
Study NCT06468696 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Performing transcriptome sequencing
Description: Performing transcriptome sequencing
Study NCT05516641 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: once daily additive to diet
Study NCT04758429 — intervention group
Intervention type: DEVICE
Intervention: Machine-learning Algorithm
Description: System technology/Software
Study NCT04889573 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: The blood samples will be collected from healthy volunteers : 7 tubes of 7 ml with anti-coagulant Héparine Lithium and 1 tube of 7ml with anti-coagulant EDTA
Study NCT05764018 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Caffeine
Description: Negligible amount of maltodextrin in flavoured drink solution containing 6 mg/kg body mass caffeine provided 45 minutes before exercise
Study NCT05764018 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hypoxia
Description: Participants will be breathing from a hypoxic gas mixture (13% O2) for the duration of the exercise bout. This will simulate an altitude of approximately 3500 m.
Study NCT05764018 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Hypoxia
Description: Participants will be breathing from a hypoxic gas mixture (13% O2) for the duration of the exercise bout. This will simulate an altitude of approximately 3500 m.
Study NCT05764018 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Negligible amount of maltodextrin in flavoured drink solution provided 45 minutes before exercise.
Study NCT05764018 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normoxia
Description: Participants will be breathing from ambient air (\~21% O2) for the duration of the exercise bout. This will provide no hypoxic stimulus as the laboratory is located relatively near sea level (295 m)
Study NCT05764018 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normoxia
Description: Participants will be breathing from ambient air (\~21% O2) for the duration of the exercise bout. This will provide no hypoxic stimulus as the laboratory is located relatively near sea level (295 m)
Study NCT05368025 — intervention group
Intervention type: DEVICE
Intervention: Mobili-T/Noona
Description: Use of two mobile health systems over a period of 6 months
Study NCT05773326 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temsirolimus
Description: TORISEL® (temsirolimus) is a kinase inhibitor indicated for the treatment of advanced renal cell carcinoma.
Study NCT05067101 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Conventional Radical Cystoprostatectomy (CRC)
Description: According to the consensus standard program, remove the accessory tissues including the bladder, prostate and seminal vesicles
Study NCT05624684 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multiplex respiratory PCR
Description: The BIOFIRE® FILMARRAY® Pneumonia plus Panel
Study NCT04740268 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Straberi
Description: The patient's entire face will be treated with the Straberi microneedling devise.~The following settings will be used as a treatment protocol. Needle length between .02- 1.55 mm
Study NCT05707598 — intervention group
Intervention type: PROCEDURE
Intervention: Laparoscopic surgery
Description: The laparoscopic approach was used for the treatment of clinical T4b colorectal cancer
Study NCT05646082 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab in Combination Antiretroviral Therapy
Description: Patients will receive dostarlimab at the fixed dose of 500 mg dose Q3W for the first 4 doses followed by a fixed 1000 mg dose Q6W until week 48 of treatment.
Study NCT06174181 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Preservative-free ophtalmic lubricant emulsion
Description: Use of a preservative-free ophtalmic lubricant emulsion continous during 6 months
Study NCT06174181 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Routine treatment
Description: Use of a preservative-free ophtalmic lubricant emulsion after each intravitreal injection during few days
Study NCT06452628 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan mobilizations
Description: The duration of the intervention will be 4 weeks, 3 sessions a week, a total of 12 sessions will be given to the study participants. Each session will last for 30 minutes. Conventional physical therapy will be given to participants along with Mulligan mobilizations.
Study NCT06452628 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Release Technique
Description: The duration of the intervention will be 4 weeks, 3 sessions a week, a total of 12 sessions will be given to the study participants. Each session will last for 30 minutes. Conventional physical therapy will be given to participants along with the Active release technique.
Study NCT06452628 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Mulligan mobilizations with active release technique
Description: The duration of intervention will be 4 weeks, 3 sessions a week, a total of 12 sessions will be given to the study participants. Each session will last for 30 minutes. Conventional physical therapy will be given to participants along with mulligan mobilizations with active release technique.
Study NCT05971004 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Arthrys (Collagen Peptide solution)
Description: one injection of collagen peptide solution (Tiss'You, Republic of San Marino) at the site of the inflamed ligament attachment point
Study NCT05971004 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Depo medrol
Description: one injection of depo-medrol at the site of inflamed ligament attachment point (femoral condyle), combined with oral slow-acting symptomatic drugs (glucosamine 1500mg, atrodar 50mg) for 3 consecutive months.
Study NCT06442852 — intervention group
Intervention type: OTHER
Intervention: exposure
Description: The observed exposure factor was the expression level of synaptic associated mirna in the serum of patients with Alzheimer's disease and healthy volunteers
Study NCT04626843 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intermittent fast
Description: 16/8 fasting method: fast for 16 hours of the day with an 8 hours feeding window for a duration of 3 months.
Study NCT06226506 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Test (T) Aprepitant injection
Description: Specification: Aprepitant injection 4.4ml∶32mg. Produced and supplied by Qilu Pharmaceutical (Hainan) Co.
Study NCT06226506 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reference (R) Aprepitant injection
Description: Specification: Aprepitant injection 4.4ml∶32mg. Produced by Heron Therapeutics, Inc and supplied by Qilu Pharmaceutical (Hainan) Co.
Study NCT04777643 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: Participants will receive a single 600mg oral dose of Epidiolex (cannabidiol) 2 hours prior to fMRI scanning.
Study NCT04777643 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive a single oral dose of placebo 2 hours prior to fMRI scanning.
Study NCT06164444 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention: Reusable drapes and gowns
Description: Reusable drapes and gowns used during surgery.
Study NCT06164444 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Comparator: Disposable (single-use) drapes and gowns
Description: Disposable drapes and gowns used during surgery.
Study NCT05943327 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu AG06474
Description: Oral Solution
Study NCT05943327 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral Solution
Study NCT05943327 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu AG06474
Description: Capsule
Study NCT05817968 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intelligent Esophageal Pressure Catheter (iEPC)
Description: Placement of the iEPC nasogastric catheter with solid state sensor for esophageal manometry.~Comparator: Esophageal balloon catheter (NutriVent).
Study NCT04975971 — intervention group
Intervention type: DRUG
Intervention: Dextenza 0.4Mg Ophthalmic Insert
Description: DEXTENZA is a corticosteroid intracanalicular insert placed in the punctum, a natural opening in the eye lid, and into the canaliculus and is designed to deliver dexamethasone to the ocular surface for up to 30 days without preservatives.
Study NCT05742087 — intervention group
Intervention type: OTHER
Intervention: Clinical examination
Description: The examination performed by the clinician of the patient will be analyzed from the cohort as previously explained.
Study NCT05742087 — intervention group
Intervention type: OTHER
Intervention: electroneuromyography (ENMG)
Description: Data from the ENMGs will be extracted from the cohort and analyzed.
Study NCT05790655 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: oPRP
Description: Prepared sample from patient's own blood collected and processed
Study NCT05790655 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: oPRP
Description: Prepared sample from patient's own blood collected and processed
Study NCT05391776 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TST002 Injection
Description: This single dose study, ascending with phase I dose-escalation principles from 200mg up to 1200mg.
Study NCT05391776 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: This single dose study, ascending with phase I dose-escalation principles from 200mg up to 1200mg.
Study NCT05739448 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: nutritional intervention
Description: The nutritional intervention will be based on the following 4 elements: nutritional follow-up by a dietician, fortified meals, tender and juicy meat dishes and fish dishes
Study NCT05739448 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical activity
Description: The physical activity intervention will be based on the following 2 elements: Follow-up with a trainer for adapted exercise and physical exercise instruction sheets
Study NCT04825184 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Body image chatbot
Description: See arm/group description.
Study NCT06024369 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CPM Device
Description: Wearable monitor used for 5 minutes per day.
Study NCT05496907 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes specialist nurse-led collaborative care intervention
Description: 10 sessions with a diabetes nurse to help improve physical and mental health outcomes
Study NCT05576623 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AdCLD-CoV19-1 OMI (Part A)
Description: 20 participants will receive investigational product (AdCLD-CoV19-1 OMI) via intramuscular injection in the deltoid muscle
Study NCT05576623 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AdCLD-CoV19-1 OMI (Part B)
Description: 250 participants will receive investigational product (AdCLD-CoV19-1 OMI) via intramuscular injection in the deltoid muscle
Study NCT05576623 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Part B)
Description: 50 participants will receive placebo via intramuscular injection in the deltoid muscle
Study NCT05271188 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Infiltration of local anaesthetic between popliteal artery and posterior knee capsule
Description: Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease pain significantly and thereby opioid consumption with minimal effect on quadriceps function \[8\]. Though ACB provides analgesia to the peripatellar and intra-articular aspect of knee joint, it does not relieve posterior knee pain which is moderate to severe in intensity \[9, 10\]. The recent technique of an ultrasound (US)-guided local anesthetic infiltration of the interspace between popliteal artery and the capsule of posterior knee (IPACK) has shown to provide significant posterior knee analgesia without affecting the common peroneal nerve (CPN) \[11\]. We postulated that IPACK will provide better pain relief and improve knee function in the immediate postoperative period compared to ACB
Study NCT04943770 — intervention group
Intervention type: PROCEDURE
Intervention: Spinal cord stimulator implant
Description: Patients will undergo spinal cord implant procedures as per standard of care and be implanted with the WaveWriter™ Alpha Spinal Cord Stimulator (SCS) system.~Implant Procedures will be followed by a healing period (4-6 weeks) during which patients will be offered therapy (up to one 1Khz). Patients will then be randomised to receive therapy at four different rates (A, B, C, D) in no particular order for 3-6 weeks each. Patients will then be followed up at 3 and 6 months after the last randomization visit.
Study NCT04943770 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Healing period
Description: Acute opioid pain medications may be continued. No additional scheduled assessments will be completed during this period.
Study NCT04943770 — intervention group
Intervention type: DEVICE
Intervention: WaveWriter™ Alpha Spinal Cord Stimulator (SCS) system
Description: Patients will then be randomised to receive therapy (up to 1KHz) at four different rates in no particular order for 3-6 weeks each. Patients will then be followed up at 3 and 6 months after the last randomization visit.
Study NCT05404906 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Given SC
Study NCT05404906 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT05404906 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive care
Description: Patients will receive disease monitoring and supportive care for any complication.
Study NCT05235698 — intervention group
Intervention type: PROCEDURE
Intervention: Ophthalmological examinations
Description: Visual acuity, slit lamp examination, eye pressure, retinophotography, indocyanine green retinal angiography, OCT-A( Optical Coherence Tomography- Angiography), adaptive optics, automated visual field
Study NCT05235698 — intervention group
Intervention type: PROCEDURE
Intervention: GlycoCheck
Description: Evaluation of the glycocalyx of sublingual capillaries with the GlycoCheck :~A sidestream dark field camera, coupled with GlycoCheck™ software is used to visualize the patient's sublingual microvascularization
Study NCT04431388 — intervention group
Intervention type: DEVICE
Intervention: ultrasound device
Description: We performe a differnt analgesic techniques to know if some of then are better
Study NCT04431388 — intervention group
Intervention type: DRUG
Intervention: Levobupivacaine
Description: using the same AL
Study NCT05838495 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: formulated liquid diet
Description: will be fed exclusively the pediatric enteral study formula with a feeding tube
Study NCT06375265 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
Description: Preoperative hybrid intervention (in-person or via phone/video) over 4 weeks using content from the CBT-I Coach app from Veteran Affairs.
Study NCT06375265 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sleep Health Education
Description: Sleep Health Education materials provided
Study NCT05686421 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OCT Imaging Using Device N
Description: Standard conventional OCT imaging device equipped with extendable and comfortable chin and forehead rest.
Study NCT05686421 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OCT Imaging Using Device C
Description: Standard conventional OCT imaging device.
Study NCT06289348 — intervention group
Intervention type: BEHAVIORAL
Intervention: socio-psychological questionnaire
Description: ton collecte socio-demographic variable
Study NCT06289348 — intervention group
Intervention type: BEHAVIORAL
Intervention: revised event impact scale (IER-S)
Description: 22 items assessed on a scale of frequency from 0 (not at all) to 4 (extremely)
Study NCT06289348 — intervention group
Intervention type: OTHER
Intervention: Non directive interview
Description: composed of a very broad opening sentence to encourage the parents' discourse
Study NCT06289348 — intervention group
Intervention type: OTHER
Intervention: Stern interview
Description: 54 questions to investigate the impact of the announcement and the parenthood construction
Study NCT06289348 — intervention group
Intervention type: OTHER
Intervention: semi-directive interview
Description: to propose ideas for improving and harmonizing practices
Study NCT06480812 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Synbiotic
Description: The proposed protocol will provide a simple but robust intervention study using a synbiotic (pre and probiotic combination) in order to improve our understanding of the mechanisms linking nutrition to health outcomes that are mediated by the gut microbiome.~This pilot study will comprise a controlled randomised intervention in which participants will be grouped into the active synbiotic arm or the control arm. The ratios will be 10g of the prebiotic supplement and 170ml of kefir. Randomisation will control for equal distribution of age and biological sex; characteristics that may confound between group comparisons and will be assessed by analysis of baseline data.