AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05482750 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance training in the fed state
Description: On the first day of evaluations, the subjects will perform the basal metabolic rate (BMR) analysis, as well as familiarization with the neuromuscular tests. After the preliminary tests, the volunteers will perform the pre-intervention procedures. Assessments of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be performed. In addition, instruments related to dietary control and physical activity level will be applied. Subsequently, in a randomized manner, participants will be allocated to one of two different interventions. During the intervention (8 weeks), the adherence to the standard diet will be verified, as well as body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be reassessed. After the 12 weeks of intervention, the volunteers will perform the evaluations referring to the post-intervention moment, following the same steps of the pre-intervention collections.
Study NCT06126250 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Power sonic toothbrush
Description: Subjects will brush twice daily for 30 seconds using a fluoride toothpaste.
Study NCT06126250 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Manual toothbrush
Description: Subjects will brush twice daily for 2 minutes using a fluoride toothpaste.
Study NCT04976582 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dry needle
Description: modalities including transcutaneous electrical nerve stimulation (TENS); electrical muscle stimulation (EMS); and interferential current (IFC). Physical agents including ultrasound, hot packs, and cold packs. Exercise including McKenzie exercises) will be administered.
Study NCT06193122 — intervention group
Intervention type: DEVICE
Intervention: Ultrasound imaging 3D and Spectroscopy
Description: Ultrasound imaging and spectroscopy will consist of collecting three dimensional data. Regions of interest in each of the tumour images and in the adjacent normal tissue will be selected for analysis.
Study NCT05044299 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Isoped
Description: Isoped is a mechanical device allowing movement of lower extremities in a forward and backward motion, with phone-based app to control resistance load
Study NCT06099080 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SM-020 gel 1.0%
Description: Subjects will apply the investigational product twice daily for 4 consecutive weeks. Subjects will be followed for 12 weeks post final application for a total of approximately 16 weeks of required participation in the study.
Study NCT05971706 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ozone therapy using a device (Ozone DTA Ozone Generator, Denta Tec Dental AS, Norway)
Description: Ozone therapy procedures will be performed immediately after non-surgical periodontal treatment and three times (every third day) within one week using a device equipped with a periodontal tip according to equipment producer recommendations. The periodontal tip will be halted 1 mm short of the pocket depth. Ozone will be applied only to the pockets; which depth is equal to or greater than 5 mm. Ozone application time to the pockets will be 30 seconds at a fixed concentration of 2,100 ppm (80% oxygen) through a connected handpiece.
Study NCT05971706 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-surgical periodontal treatment
Description: Non-surgical periodontal treatment consists of oral hygiene instructions, full mouth supragingival scaling using hand instruments, ultrasonic devices, polishing, and subgingival debridement under local anesthesia with sharp Gracey and Universal curettes and ultrasonic instruments in a single appointment.
Study NCT05971706 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-surgical periodontal treatment
Description: Non-surgical periodontal treatment consists of oral hygiene instructions, full mouth supragingival scaling using hand instruments, ultrasonic devices, polishing, and subgingival debridement under local anesthesia with sharp Gracey and Universal curettes and ultrasonic instruments in a single appointment.
Study NCT05549921 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NY-ESO-1(TCR Affinity Enhancing Specific T cell Therapy)
Description: NY-ESO-1(TCR Affinity Enhancing Specific T cell Therapy)
Study NCT05667337 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CLP-PEG-MPC
Description: Implantation of a 500 um thick biosynthetic corneal implant utilizing DALK surgical technique
Study NCT05667337 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Human donor cornea penetrating keratoplasty
Description: Implantation of a human donor cornea graft utilizing PKP surgical technique
Study NCT05330104 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Ecological Momentary Assessment
Description: mEMA is a tool that allows for scheduled or triggered surveys to assess a participant's CIPN symptoms and/or fall risk
Study NCT06287177 — intervention group
Intervention type: DRUG
Intervention: Inclisiran
Description: Injection
Study NCT05503238 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Skin-to-skin contact
Description: Preterm infants will receive maternal-infant skin-to-skin contact at least 1 continuous hour everyday from infant 3 days of life until discharge, and other nursing care will be same as the routine group. During skin-to-skin contact, place naked baby only with diaper on the mother's bare chest in an upright position and tilt the baby's head to one side in a slightly extended position to keeps the airway open, cover the infant with a blanket to keep them warm. A neonatal nurse will be stay with mother and infant to observe and support.
Study NCT05503238 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Routine care
Description: Preterm infants will receive standard nursing care provided by neonatal nurses in accordance with hospital principles during hospitalization.
Study NCT05503238 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Routine care
Description: Preterm infants will receive standard nursing care provided by neonatal nurses in accordance with hospital principles during hospitalization.
Study NCT05570461 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Modified Constraint-Induced Movement Therapy
Description: Experimental group will receive Modified Constraint-Induced Movement Therapyand traditional physical therapy to the impaired upper limb based on the repetitive training of functional activities and behavioral shaping and a task-oriented approach, while the unaffected arm of subjects in the mCIMT group will be constrained by wearing a mitten during the treatment session and for 3 hours/day outside the therapy hours, 6(six) days/week for two weeks by an experienced Physical therapist.The time duration for Group A will be 40 minutes.
Study NCT05570461 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Constraint-Induced Movement Therapy
Description: Experimental group will receive Modified Constraint-Induced Movement Therapyand traditional physical therapy to the impaired upper limb based on the repetitive training of functional activities and behavioral shaping and a task-oriented approach, while the unaffected arm of subjects in the mCIMT group will be constrained by wearing a mitten during the treatment session and for 3 hours/day outside the therapy hours, 6(six) days/week for two weeks by an experienced Physical therapist.The time duration for Group A will be 40 minutes.
Study NCT03843008 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Melatonin
Description: Participants in the Melatonin Group will receive 3mg of melatonin each evening for up to seven days for a maximum total of 21mg of melatonin.
Study NCT05396599 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Model DIU
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.
Study NCT05396599 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Model DFW
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.
Study NCT05396599 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Model ZCT
Description: Subjects will be randomized to a treatment group (masked) in ratio 1:1:1. Surgeons will perform standardized, small-incision, cataract surgery and implant the study lenses using a JJSV-validated insertion system qualified for use with the lens to be implanted.
Study NCT05552417 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pectointercostal facial plan block
Description: Pectointercostal facial group (PI) (n=--) where --children will have bilateral Pectointercostal Block.
Study NCT05822765 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine concentration of 1:1000000
Description: Tumescence fluid contained Epinephrine concentration of 1:1000000 (one ampoule 1 mg per liter) lidocaine 500 mg and sodium bicarbonate 8.4% 10 ml per liter
Study NCT05822765 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine concentration of 1:500000
Description: Tumescence fluid contained Epinephrine concentration of 1:500000 two ampoule 2 mg/liter with same lidocaine and bicarbonate dose. lidocaine 500 mg and sodium bicarbonate 8.4% 10 ml per liter
Study NCT05692336 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vestibular training
Description: balance training in the form of vestibular training
Study NCT05692336 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dual task training
Description: balance training in the form of dual task training
Study NCT05675644 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone-only pill
Description: Single dose based on adaptive dose-finding design
Study NCT05969847 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: split-course hypofraction radiotherapy
Description: After reaching a cumulative radiotherapy dose of 25Gy in the entire pelvic cavity (PTV1), the treatment field was subsequently narrowed to solely focus on the primary tumor (PTV2), with a total dose of 35Gy administered. All patients will undergo fractionated radiotherapy, following a regimen of 7Gy per fraction, delivered every 3 weeks for five cycles.
Study NCT05969847 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAPOX
Description: Drug: Oxaliplatin,130mg/m2，ivgtt，d1,for 6 cycles. Drug: Capecitabine,1000mg/m2，po，bid，d1-14, for 6 cycles.
Study NCT05969847 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab
Description: Envafolimab is administered by subcutaneous injection. The recommended dose is 300 mg per 3 weeks (Q3W) for 6 cycles.
Study NCT05969847 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Local excision
Description: Local full-thickness resection is employed for patients with clinical complete response (cCR) or near-clinical complete response (ncCR) following TNT.
Study NCT05155189 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: C-CAR031
Description: Targeting GPC3 armored CART cell injection (C-CAR031)
Study NCT05155189 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Tyrosine kinase inhibitors
Study NCT05155189 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1(L1) monoclonal antibody
Description: Immune checkpoint inhibitors, ICIs
Study NCT05799248 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rhPSMA-7.3 (18F)
Description: Patients will receive a dose with an administered activity of 8 mCi (296 MBq) ± 20% of rhPSMA-7.3, delivered as an IV bolus injection with a 10 mL fast 0.9% sodium chloride flush, followed by PET imaging.
Study NCT04801056 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TB006
Description: TB006 monoclonal antibody
Study NCT04801056 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo i.v. infusion
Study NCT05842356 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communication Technique 2
Description: A new communication technique.
Study NCT05533229 — intervention group
Intervention type: DRUG
Intervention: Fentanyl
Description: The trial aims to study the quality of anesthesia and perioperative analgesia and patient's satisfaction provided by fentanyl and bupivacaine versus morphine and bupivacaine.
Study NCT05533229 — intervention group
Intervention type: DRUG
Intervention: Morphine
Description: The trial aims to study the quality of anesthesia, perioperative analgesia and patient's satisfaction provided by fentanyl and bupivacaine versus morphine and bupivacaine.
Study NCT06427135 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise interventions
Description: Rehabilitation physician or rehabilitation therapist, to engage in physical exercise or patients, according to the medical examination data (including exercise test and physical strength test), according to their health, physical strength, and cardiovascular function status, with the form of a prescription for the type of exercise, intensity of exercise, exercise time and frequency of exercise, to put forward the precautions to be taken during exercise.
Study NCT05591235 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: After the screening period, eligible subjects took the hyperinsulinemic euglycemic clamp test and were then admitted to insulin with metformin for 4 weeks. During this timeframe, all patients were instructed to change the insulin pump infusion site and provide one profile of 7-point self-monitored blood glucose every three days. The insulin doses were titrated every day by physicians to achieve the glycemic goal. Participants who failed to attain the glycemic target in three consecutive times or could not afford the side effects of hypoglycemic medications were excluded from this study. On the last day of week 4, a FreeStyle Libre Pro Sensor (FGM system) was inserted to record the glycemic data for up to 14 days. At the end of week 5, all antidiabetic agents were stopped and the hyperinsulinemic euglycemic clamp test was performed again for remaining subjects.
Study NCT05591235 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin
Description: After the screening period, eligible subjects took the hyperinsulinemic euglycemic clamp test and were then admitted to insulin with dapagliflozin (100mg one day) for 4 weeks. During this timeframe, all patients were instructed to change the insulin pump infusion site and provide one profile of 7-point self-monitored blood glucose every three days. The insulin doses were titrated every day by physicians to achieve the glycemic goal. Participants who failed to attain the glycemic target in three consecutive times or could not afford the side effects of hypoglycemic medications were excluded from this study. On the last day of week 4, a FreeStyle Libre Pro Sensor (FGM system) was inserted to record the glycemic data for up to 14 days. At the end of week 5, all antidiabetic agents were stopped and the hyperinsulinemic euglycemic clamp test was performed again for remaining subjects.
Study NCT05591235 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fixed-dose combination of metformin and pioglitazone (500mg metformin plus 15mg pioglitazone)
Description: After the screening period, eligible subjects took the hyperinsulinemic euglycemic clamp test and were then admitted to insulin with fixed-dose combination of metformin and pioglitazone (two tablets of 500mg metformin plus 15mg pioglitazone) for 4 weeks. During this timeframe, all patients were instructed to change the insulin pump infusion site and provide one profile of 7-point self-monitored blood glucose every three days. The insulin doses were titrated every day by physicians to achieve the glycemic goal. Participants who failed to attain the glycemic target in three consecutive times or could not afford the side effects of hypoglycemic medications were excluded from this study. On the last day of week 4, a FreeStyle Libre Pro Sensor (FGM system) was inserted to record the glycemic data for up to 14 days. At the end of week 5, all antidiabetic agents were stopped and the hyperinsulinemic euglycemic clamp test was performed again for remaining subjects.
Study NCT04927169 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Interleukin-7
Description: IM administration at 10μg/kg twice a week for three weeks and up to 7 administrations according to Hospital length of stay
Study NCT04927169 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: PLACEBO
Description: IM administration of a volume of saline identical to 10μg/kg CYT107, twice a week for three weeks and up to 7 administrations according to Hospital length of stay
Study NCT06133504 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Early Multimodal Therapy
Description: Early multimodal therapy is defined as the collection of therapeutic maneuvers performed by the physiotherapy, speech therapy, respiratory therapy, and occupational therapy team at the time of study inclusion.
Study NCT06133504 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Late Multimodal Therapy
Description: Late multimodal therapy is characterized by the same set of maneuvers carried out by the same disciplinary team, but it is initiated once indicated by the attending physician.
Study NCT06020872 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health literacy program
Description: Health literacy program was the health education related to healthy plate.
Study NCT05742308 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Laughter yoga
Description: Laughter yoga program was composed of four steps. The first step, which took 10 minutes, had warm-up exercises including gentle stretching and hand clapping. The second step, which included deep breathing exercises and hand clapping, took 5 minutes. The third step involved children's games and laughter exercises. The sessions included a combination of different laughter exercises. The last step, which included yoga nidra took 5 minutes.
Study NCT04387240 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Artemisinin / Artesunate
Description: testing the drug capabilities in reducing the shedding and causing the testing for covid 19 to become negative
Study NCT04387240 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo or sham drug will be given to the second arm
Study NCT05453149 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integrated Physical Activity and Behavioural Change Intervention
Description: Physical Activity (PA) Component: A group-based PA program geared to the level of injury and mobility delivered through web conferencing software. Participants select at three sessions weekly over 10 weeks. Sessions include 45 mins of exercise (i.e boxercise; aerobics; yoga) and 15 mins of social interaction with the group.~Behavioural Change Component: Participants will also receive synchronous 1:1 sessions (approximately 20 mins/week) with a trained clinician on behavioural strategies to initiate and maintain engagement in PA over the 10-week period. Content of the sessions includes: providing information on PA and the self-management of impairments and related symptoms; evaluating barriers to engagement (e.g. fear of injury); and behavioural strategies.
Study NCT05032924 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PPR group with ESWT
Description: extracorporeal shock wave (ESWT) (STORZ MEDICAL Extracorporeal Shock Wave Therapy) (3000 impulse, each point, 24 KV, 0.32 mJ/mm2) one week after PRP or HA injection
Study NCT05032924 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PPR group without ESWT
Description: PRP or HA injection only
Study NCT05032924 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: HA group with ESWT
Description: extracorporeal shock wave (ESWT) (STORZ MEDICAL Extracorporeal Shock Wave Therapy)
Study NCT05032924 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: HA group without ESWT
Description: PRP or HA injection only
Study NCT06110637 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hard shoes runners evaluation
Description: The hard shoes runners get on the treadmill for 21 km at a speed corresponding to 70 percent (%) of their the maximum aerobic speed (MAV) and are evaluated.
Study NCT06110637 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Soft shoes runners evaluation
Description: The soft shoes runners get on the treadmill for 21 km at a speed corresponding to 70 percent (%) of their the maximum aerobic speed (MAV) and are evaluated.
Study NCT04708457 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: VV-ECMO
Description: Early use of VV-ECMO in SARI patients.
Study NCT05686044 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buntanetap/Posiphen
Description: HPMC (vegetarian source) capsule shells
Study NCT04551638 — intervention group
Intervention type: OTHER
Intervention: Psychological assessment with the Repertory Grid Technique
Description: The RGT is a constructivist psychological tool to explore the structure and content of personal identity.
Study NCT04835493 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: In the proposed study, we will conduct a randomized clinical trial of low-income, adult Latino(a)s with type 2 diabetes randomized at the individual level a telehealth-supported, integrated CHWs, medication-access, diabetes education program) (intervention) versus usual care (UC). Our research team will provide telementoring to local clinic teams (providers and CHWs) to initiate the 12-month the program into their clinics.