AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05107778 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo orally once daily.
Study NCT05700799 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Advocate
Description: The Health Advocate intervention will include helping pediatric liver transplant recipients and their families address unmet household social needs (e.g., food insecurity), improve patient-provider communication, and enhance care coordination.
Study NCT06524804 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BY101298 Capsules
Description: An oral DNA-PK Inhibitor
Study NCT06524804 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: palliative radiotherapy
Description: Undergo palliative radiotherapy
Study NCT06524804 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: curative radiotherapy
Description: Undergo curative radiotherapy
Study NCT05941052 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Tongue swab-based molecular assays
Description: The investigators will evaluate semi-automated or automated molecular assays intended for use at near point of care or point of care.
Study NCT05561088 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scalp Acupuncture
Description: mplementation plan of head needle: The middle frontal line (MS1), the middle parietal line (MS5) and the back parietal and temporal oblique line (MS7) in the International Standardization Program for the Name of the first needle Point in 1989 were selected, and the needles were inserted along the shape of each section. One needle was inserted into the middle frontal line and the middle parietal line, and two needles were inserted into the back parietal and temporal oblique line. The KWD-808I pulse electrotherapy instrument produced by Changzhou Wujin Great Wall Medical Equipment Co., Ltd. is used on the needle handle after lifting, inserting and twisting. The continuous waveform was used, the voltage was 2-4 V, the frequency was 60-80 times /min, the intensity was tolerated by the patient, the needle was kept for 30min, and the treatment was performed once a day.
Study NCT05561088 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The treatment recommended in the guidelines for acute ischemic stroke was administered
Description: The treatment recommended in the guidelines for acute ischemic stroke was administered
Study NCT04750590 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: en bloc resection, morcellation
Description: Laser en bloc resection with subsequent tumor morcellation will be performed. This tissue will be sent for histology in order to estimate the histological subtype and differentiation grade. Next stage laser resection of the tumor basis will be performed with subsequent histology to determine the depth of invasion and the status of surgical margin.
Study NCT04750590 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: piecemeal resection, tissue removal by loop
Description: Tumor piecemeal resection will be performed with electric loop. Then fragments of the tumor will be removed by the loop or Janet's syringe. Fragments from the base of the tumor will be sent separately in order to assess which stage the tumor is at and its surgical margin status.
Study NCT06385470 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dynamic Temporal and Tactile Cueing treatment
Description: DTTC is a motor-based treatment designed for children with CAS who may have limited verbal output. It applies the principles of motor learning and focuses on speech movement gestures in the context of functional words and phrases.~The participants will receive two versions of the DTTC treatment (i.e., DTTC in English \[DTTC-E\] and DTTC in Cantonese \[DTTC-C\]), where probe data will be collected before, during, between and after the treatment intervention.
Study NCT06661031 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Enhancement Therapy plus Ecological Momentary Intervention
Description: Two Motivational Enhancement Therapy (MET) sessions (1st, \~45 minutes; 2nd, \~30 minutes) between counselor and participant occur one week apart. MET sessions are personalized, interactive, face-to-face, and delivered according to a manual. MET session discussion topics include triggers for cannabis use, life goals/values, and development of a change plan. Participants then complete a 2-week Ecological Momentary Intervention (EMI) period. Survey prompts are sent 4x/day (3x/day at quasi-randomized times, 1x/day at fixed time; \~2 mins each) that ask about the participant's recent cannabis use. Depending on answers reported, the participant can receive tailored messages that support their self-efficacy and prompt use of coping strategies.
Study NCT06661031 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Enhanced Usual Care
Description: Participants meet with a study counselor 1-on-1 via videoconference to review a brochure containing cannabis information and treatment resources.
Study NCT06613555 — intervention group
Intervention type: OTHER
Intervention: Retinal imaging
Description: the retinal imaging work-up includes:~* OCT-angiography~* Retinophotography~* Adaptive optics~performed at inclusion, at 6 months and then once a year for 10 years for patients Only performed at inclusion for controls
Study NCT06613555 — intervention group
Intervention type: BIOLOGICAL
Intervention: Biological check-up
Description: it is performed at inclusion and then once a year for 10 years for patients~Only performed at inclusion for controls
Study NCT04832412 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BrainPhyt
Description: BrainPhyt low dose supplementation during 6 months
Study NCT04832412 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: 100 % Maltodextrin
Description: 100 % Maltodextrin
Study NCT06696898 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Somatosensory Motor Control Exercises
Description: The Somatosensory motor control training protocol assembled into three components, 1) PNF exercises (Each patient alternately contracted trunk extensors and flexors isometrically for 10 seconds against maximum resistance while seated, then contracted trunk agonists alternately in a concentric and eccentric manner against manual resistance without relaxing, then moved his or her trunk in a twisting and diagonal orientation against maximum resistance), 2) Somatosensory exercises in which a wobbling board was used and six types of exercises were performed including hallowing, one lower limb elevation, opposite upper and lower limb elevation from a four-limb supported position (quadruped), abdominal reinforcement, maintaining a bridging posture, and one lower limb elevation from the bridging posture, and 3) finally Vestibular training which involved exercises to improve gaze focus, exercises for enhancing eye movements.
Study NCT06696898 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Myofascial Release Technique
Description: Manual therapy technique that applies sustained pressure to myofascial tissues around the lumbar spine and pelvis to release tension and improve mobility.Myofascial Release Technique MFR is given with the ulnar border from proximal to distal direction with a light gentle pressure over the hamstring muscle until the slack in the skin is loosened. (2) Every strike is to be held for 30 seconds, 5 repetitions per session
Study NCT06696898 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sensorymotor training
Description: The Somatosensory motor control training protocol assembled into three components, 1) PNF exercises (Each patient alternately contracted trunk extensors and flexors isometrically for 10 seconds against maximum resistance while seated, then contracted trunk agonists alternately in a concentric and eccentric manner against manual resistance without relaxing, then moved his or her trunk in a twisting and diagonal orientation against maximum resistance), 2) Somatosensory exercises in which a wobbling board was used and six types of exercises were performed including hallowing, one lower limb elevation, opposite upper and lower limb elevation from a four-limb supported position (quadruped), abdominal reinforcement, maintaining a bridging posture, and one lower limb elevation from the bridging posture, and 3) finally Vestibular training which involved exercises to improve gaze focus, exercises for enhancing eye movements.
Study NCT06723392 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral nitrofurantoin monohydrate/macrocrystals
Description: 7-day course of oral nitrofurantoin monohydrate/macrocrystals 100 mg twice daily (total of 14 doses)
Study NCT06723392 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 7-day course of oral placebo 100 mg twice daily (total of 14 doses)
Study NCT06731699 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FD-001
Description: The initial dose was 0.4mg, and subsequent doses of 0.8mg, 1.6mg, 2.4mg, 3.2mg, and 4.0mg were proposed to be administered in a progressive manner using the rapid titration method combined with the traditional 3+3 experimental design. The trial process consists of three periods: screening period, treatment period, and follow-up period. The screening period lasted from D-28 to D-1 for treatment (DLT observation period): during this time frame, there was a single administration period (C0D1-C0D4) where oral administration occurred on day one followed by safety observations on days two to four; as well as multiple administration period one (C1D1-C1D28) where oral administration took place on days one to two and seven to nine with rest periods in between. The drug is available in capsule form.
Study NCT06739343 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: PHACO-Trabeculectomy
Description: Phaco-Trabeculectomy is a combined surgical procedure that integrates phacoemulsification, a modern cataract extraction technique using ultrasound, with trabeculectomy, a glaucoma filtration surgery. This intervention is distinguished by its precision, minimal incision size, and suitability for patients with coexisting cataract and glaucoma. Phacoemulsification efficiently emulsifies and aspirates the cataract through a small incision, while trabeculectomy creates a filtration bleb to lower intraocular pressure (IOP). This combination allows for simultaneous management of both conditions, particularly in cases where phacoemulsification is preferred for cataract extraction.
Study NCT06739343 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: MSICS-Trabeculectomy
Description: Manual Small Incision Cataract Surgery (MSICS) with Trabeculectomy is a cost-effective, combined surgical approach involving a manual technique for cataract removal alongside glaucoma filtration surgery. MSICS utilizes a larger incision than phacoemulsification, allowing for the manual extraction of the cataract nucleus. This procedure is particularly advantageous in resource-limited settings where phacoemulsification equipment may not be available. The trabeculectomy component is the same as in the PHACO-Trabeculectomy intervention, providing effective IOP reduction through the creation of a filtration bleb.
Study NCT05381636 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Esophageal arterial infusion chemotherapy
Description: Percutaneous femoral artery puncture was performed to search for feeding arterial vessels corresponding to the lesion, and chemotherapeutic drugs were directly injected into the tumor vessels via targeted blood vessels.
Study NCT06739304 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Relapse Prevention
Description: 250 adult USD females of Intervention group received the 8-week Group mindfulness intervention performed by psychiatrists.
Study NCT06739967 — intervention group
Intervention type: BEHAVIORAL
Intervention: Behavioral Treatment
Description: The SLT intervention will be entirely administered online through a web-based platform. While each of the treatments will engage semantics, phonology, and orthography, the protocols will be tailored relative to the characteristics of each PPA variant. Patients with svPPA and lvPPA will undergo a lexical retrieval training (LRT) intervention implemented using a training cascade.~Patients with nfvPPA will undergo Video-implemented Script Training (VISTA), a choral reading approach training accurate production of functional scripts. The method is based on that implemented in American-English individuals with PPA and aims at improving grammar and motor aspects of speech production by taking advantage of repetitive practice and automaticity.
Study NCT06739525 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Blue Light-Blocking Glasses (Intervention Group)
Description: Participants in this arm wore blue light-blocking glasses designed to filter out a portion of short-wavelength blue light. These lenses were intended to reduce eye strain and protect against blue light exposure, especially during prolonged screen time. Participants used blue light-blocking glasses consistently throughout the study period to assess their effect on contrast sensitivity and visual fatigue.
Study NCT06739525 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Standard Lenses (Control Group)
Description: Participants in this arm wore standard lenses without any blue light-blocking properties. These lenses allow the full spectrum of visible light to pass through and serve as a baseline control to measure against the blue light-blocking glasses. Participants used these lenses under the same conditions to assess contrast sensitivity and visual fatigue without blue light filtration.
Study NCT06736886 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light application
Description: Light application
Study NCT06736886 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Light application
Description: Light application
Study NCT06736938 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol 1%
Description: Propofol 1% is infused intravenously, initially at a bolus dose of 0.5 mg/kg followed by a maintenance dose in a continuous infusion of 0.5-1.0 mg/kg/hour.
Study NCT06736938 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: Midazolam is administered intravenously at an initial dose of 2 mg, as a bolus, followed by aliquots of 0.5 mg or 1 mg.
Study NCT06736938 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pethidine
Description: Pethidine (100 mg/2 ml) is administered intravenously at a dosage of 0.5 mg/kg.
Study NCT05381636 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Systemic intravenous chemotherapy
Description: Albumin paclitaxel 125 mg / m2, D1, D8 + cisplatin 75 mg / m2, D1, every 3 weeks for 1 cycle
Study NCT06781840 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Playing Playfully to Overcome Adversity
Description: The intervention will consist of two parts: (a) five 45-minute-long parent group online sessions; and (b) one 30-minute long online guided play session with OTS/OT.The training will consist of asynchronous module and PowerPoint presentations followed by role play and discussions.
Study NCT06781840 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Playing Playfully to Overcome Adversity
Description: The intervention will consist of two parts: (a) five 45-minute-long parent group online sessions; and (b) one 30-minute long online guided play session with OTS/OT.The training will consist of asynchronous module and PowerPoint presentations followed by role play and discussions.
Study NCT05428826 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Phase 4 Prednisone Dose : 1mg/kg/day at inclusion Route of administration : oral Duration of treatment: 9 to 21 months.
Study NCT06780189 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking
Description: This study is designed to evaluate the relationship between passive smoking and the vital parameters of children undergoing deep sedation. Additionally, the study aims to comprehensively assess and document the entire treatment process from start to finish by using the RASS, MASS, and PAED scales for postoperative evaluation.
Study NCT06661265 — intervention group
Intervention type: PROCEDURE
Intervention: adjuvant tomotherapy +- chemotherapy after the reconstructive surgery with flaps
Description: adjuvant treatment in locally-advanced head and neck cancers submitted to upfront surgery with flap reconstruction, evaluation of toxicity and flap status performed at San Raffaele Hospital between December 2017-December 2022.
Study NCT06671145 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: catheter ablation
Description: Catheter ablation after differentiating Atrioventricular Nodal Reentry Tachycardia from Orthodromic Atrioventricular Reentry Tachycardia during electrophysiological study.
Study NCT05663255 — intervention group
Intervention type: DRUG
Intervention: Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)
Description: Discontinuation or reduction of at least one respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)
Study NCT06673121 — intervention group
Intervention type: DRUG
Intervention: Traditional Chinese Medicine
Description: Received treatment with traditional Chinese medicine
Study NCT06672211 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video-supported training
Description: Patients with stomas were provided with video-supported training in addition to standard stoma care training.
Study NCT06672029 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: combining pattern-specific manual therapy, Schroth Best Practice exercise, and Gensingen brace application
Description: * The pattern-specific manual therapy: It was developed by our author. This therapy was done immediately before each SBP (Schroth Best Practice) exercise session, targeting both the spine and extra-spinal regions.~* The Schroth Best Practice exercises: It contains following 6 components: The physio-logic® program for sagittal profile correction, education on activities of daily living (ADLs), the 3D made easy program, the new Power Schroth program, the rehabilitation of walk, and neuromobilization.~* The Gensingen brace application: it was made according to the patients' Lehnert Schroth Classifications. the investigators recommended the patients to wear the brace for 21-23 hours per day during the first year. As the bone maturation reached Risser 4 to 4.5, the daily brace wearing time was gradually reduced.
Study NCT06003816 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) CATI
Description: The CHoBI7 program is during group sessions by a health promoter to those residing in a ring around a cholera patient reinforced through weekly voice and text messages from the CHoBI7 mHealth program over 12 months on the recommended water, sanitation, and hygiene behaviors.
Study NCT06003816 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard message
Description: Standard message given in the Democratic Republic of the Congo to diarrhea patients at health facility discharge on use of oral rehydration solution
Study NCT06123429 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Stress reduction
Description: The MBSR course will consist of weekly sessions lasting two and a half hours, involving lecture, meditation, and self-reflection.~Mindfulness-Based Stress Reduction (MBSR) is a structured program designed to help individuals manage stress, increase self-awareness, and promote overall well-being. Developed by Dr. Jon Kabat-Zinn in the late 1970s, MBSR combines elements of mindfulness meditation and cognitive-behavioral techniques. MBSR is a comprehensive program that equips individuals with practical skills to better manage stress and enhance their mental and emotional well-being. Its emphasis on mindfulness, self-awareness, and the integration of these practices into daily life makes it a valuable resource for those seeking to reduce stress and improve their overall quality of life.
Study NCT04955990 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PAH Therapies
Description: No Drug will be administered as part of this study. Real world data will be collected in participants who newly initiate PAH therapies in routine clinical setting or have already been receiving macitentan 10 mg for at least 3 months prior to the index date.
Study NCT05664646 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DS8R
Description: transcutaneous stimulation of the spinal cord.
Study NCT05664646 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Arm Ergometry
Description: Study 1 will use the arm ergometry as a form of exercise.
Study NCT05664646 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Arm Ergometry
Description: Study 1 will use the arm ergometry as a form of exercise.
Study NCT05664646 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cool Environment
Description: Study 2 will be completed in a cool environment setting.
Study NCT05664646 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Cool Environment
Description: Study 2 will be completed in a cool environment setting.
Study NCT05026385 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Targeted nutrition advice, progressive resistance training exercise, and self-management support