AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05866588 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical, psychological and spiritual nursing care (Nursing Therapeutics)
Description: 1. Follow-up: To make a presentation about the physiological and psychological changes during pregnancy. do dream work~2. Follow-up: Providing education and counseling for childbirth.~3. Follow-up: Training and role rehearsal on mother-infant interaction, breastfeeding and infant care.~4. Follow-up: To provide counseling on the issues needed with the approaching of the birth.~5. Follow-up: Teaching about conscious parenting and mother-infant, father-infant interaction.~6. Tracking. To provide education, counseling and social support on the other roles of the mother in life such as wife role, working woman role, social role.~7. Follow-up: To evaluate the transition to motherhood.~8. Follow-up: To evaluate the outcomes of transition to motherhood and adjustment to motherhood according to expected completion time.
Study NCT05970796 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic floor muscle training
Description: The pelvic floor muscle training program will be provided via an intra-vaginal biofeedback device - Smart Kegel Trainer, which will be connected to the product application installed on the mobile phone or tablet so the participants can monitor their pelvic floor contractions in real time and directly in the application. Participants will be asked to complete three sets of 8 to 12 maximal pelvic floor muscle contractions and three to ten fast contractions per training session. The home program will be tailored to each participant and include pelvic floor safe exercises recommended by the Continence Foundation of Australia.
Study NCT06688812 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Perceptual Motor Training
Description: 8 set of exercises~1. Balance training and related exercises~2. Tones of awareness training, body parts' role and related exercises~3. Space awareness training and related exercises~4. Perception of shape training and related exercises~5. Visual perception training and related exercise.~6. Kinesthetic-tactile perception training and related exercises~7. Auditory perception training and related exercises~8. Eye and hand coordination, ﬁne motor movements and related Exercises
Study NCT04737057 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SDF
Description: Apply this topical medication through : 1)Dry with a gentle flow of compressed air to decayed tooth surfaces. 2) Bend micro sponge brush to remove excess liquid before application apply SDF directly to only the affected tooth surface. 3) Apply the SDF material 4)Dry with a gentle flow of compressed air for at least one minute. and Remove excess SDF with gauze
Study NCT04737057 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hall technique
Description: this technique is performed through :1) Orthodontic separator being stretched between two pieces of floss, then placed between the contact points of primary molars (for five days.) 2)The correct size of crown will not impinge on the teeth on either side, and a slight 'spring back' will be felt when the PMC is gently pushed up to (but not through) the contact points and the PMC has been filled with a Riva self-cure capsule cement, extruded cement is quickly wiped away and the child is asked to keep biting on the crown for two minutes, until the cement is set, to prevent 'spring back' of the PMC from the fully seated position
Study NCT05739708 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaires
Description: The time to complete the different questionnaires is estimated to be 60 minutes.
Study NCT06017323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: 1000mg/m2 IV given days 1, 8, and 15every 28 days (1 cycle)
Study NCT06017323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: 125 mg/m2 given days 1, 8, and 15every 28 days (1 cycle)
Study NCT06017323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proglumide Dose level 1
Description: Daily dose of 1200 mg orally given as400 mg orally (PO), three times a day(TID) (dose level 1)
Study NCT06017323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proglumide Dose level 2
Description: Daily dose of 1600 mg orally given as800 mg orally (PO) twice a day (BID)(dose level 2).
Study NCT04737057 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hall technique
Description: this technique is performed through :1) Orthodontic separator being stretched between two pieces of floss, then placed between the contact points of primary molars (for five days.) 2)The correct size of crown will not impinge on the teeth on either side, and a slight 'spring back' will be felt when the PMC is gently pushed up to (but not through) the contact points and the PMC has been filled with a Riva self-cure capsule cement, extruded cement is quickly wiped away and the child is asked to keep biting on the crown for two minutes, until the cement is set, to prevent 'spring back' of the PMC from the fully seated position
Study NCT05459805 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: traditional chinese medicine Xuanfei-Zhike formula
Description: 200ml, bid, for 8 weeks
Study NCT05459805 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: inhaled corticosteroids (ICS) and long-acting β2-agonist (LABA)
Description: one suction, q12h, for 8 weeks
Study NCT05459805 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: inhaled corticosteroids (ICS) and long-acting β2-agonist (LABA)
Description: one suction, q12h, for 8 weeks
Study NCT04971811 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Snack with energy density less than 1.5 kcal/g
Description: Snack meal with snack food having energy density less than 1.5 kcal/g
Study NCT04971811 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Snack with energy density greater than 1.5 kcal/g
Description: Snack meal with snack food having energy density greater than 1.5 kcal/g
Study NCT05669885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sildenafil
Description: Study participants will be allocated to receive oral administration of 100 mg sildenafil.
Study NCT06312969 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video game based training
Description: Type of intervention: Cognitive training through 3 types of video games:~* Serious games or brain-training games.~* Exer-gaming~* Skill-training games~Method of administration: The patient will receive the treatment for a period of 12 weeks, in which they will commit to use the video games of the intervention with the following pattern:~* Brain-training game: sessions of 7-12 minutes with a frequency of 4 days a week.~* Exer-gaming: sessions of 15-20 minutes 2 days a week.~* Skill-training games: sessions of 15-20 minutes 2 days a week.
Study NCT06688812 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Repetitive Facilitation Exercises
Description: Eight set of exercises:~1. Shoulder Flexion with 90° Elbow Flexion (Supine).~2. Shoulder Horizontal Extension/Flexion with Elbow flexion (supine).~3. Complex Shoulder and Upper Limb Movements (Supine)~4. Shoulder Flexion/Abduction/External Rotation with Elbow and Forearm Supination (Supine)~5. Forearm Supination/Pronation with 90° Elbow Flexion (Sitting)~6. Wrist Extension and Forearm Pronation with Finger Extension (Supine)~7. Finger Extension with Wrist Flexion (Supine)~8. Finger Extension/Flexion with Wrist Flexion (Sitting) • Therapist facilitate the movement by rubbing, tapping and gentle stretching.
Study NCT06685796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEBT-209 capsules
Description: BEBT-209 Capsules, dosage: 150mg, frequency and duration of administration: administered on days 1, 2, 8, and 9 of each cycle, with a 21-day cycle. On days 1 and 8, take orally once before dinner or twice (before breakfast and before dinner), and on days 2 and 9, take orally once before breakfast.
Study NCT06685796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin injection
Description: Carboplatin injection, dosage: AUC 2 × (creatinine clearance rate + 25), frequency and duration of administration: administered on days 1 and 8 or days 2 and 9 of each cycle, with a 21-day cycle.
Study NCT06685796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine hydrochloride for injection
Description: Gemcitabine hydrochloride for injection, dosage: 1000mg/m², frequency and duration of administration: administered on days 1 and 8 or days 2 and 9 of each cycle, with a 21-day cycle.
Study NCT06686719 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post Facilitation
Description: For hamstring muscle, the patient positioned in supine with hip and knee flexed to mid- range. For calf muscle, the patient positioned in supine with straight leg. Now therapist ask the subjects to isometrically contract the hamstring and calf using 30 % of the strength for 15 seconds by attempting to push the leg back toward the therapist and relax. The therapist then passively stretched the muscle until a mild stretch sensation was reported. The stretch was held for another 10 seconds. This sequence will repeat 5 times on each subject in the group.~Stretching of the hip flexors, adductors and plantar flexors. Functional training includes bridging, kneeling and sit to stand.
Study NCT06686719 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Post Isometric Relaxation
Description: For hamstring muscle, the patient positioned in supine with hip and knee flexed. For calf muscle, the patient positioned in supine with straight leg. Now therapist ask the subjects to isometrically contract the hamstring and calf using 25 % of the strength for 7-10 seconds by attempting to push the leg back toward the therapist and relax.After relaxation, the therapist further extends the knee for 3 to 5 seconds.. This sequence will repeat 5 times on each subject in the group.~Stretching of the hip flexors, adductors and plantar flexors. Functional training includes bridging, kneeling and sit to stand.
Study NCT06686719 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial Release
Description: MFR for Hamstring muscle will be given with patient in prone position with 120 second hold. For giving the MFR, the thumb of the therapist will be allowed to sink in to the central portion of the hamstring. It will held for 120 seconds to allow the tissue to soften and then myofascial structures will spread in a lateral direction until feeling of first fascial barrier. MFR will be performed for 15 mins.~Stretching of the hip adductors, hip flexors and plantar flexors. Functional training includes kneeling, bridging and sit to stand.
Study NCT06695559 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Labrida Bioclean
Description: Debridement on the active comparator group will be implemented on the implant surface with Labrida Bioclean (i.e. the chitosan brush).
Study NCT06695559 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Labrida Bioclean and tetracycline slurry
Description: On the experimental group debridement of the implant surface will be carried out with Labrida Bioclean and thereafter irrigation of the periimplant sulcus with tetracycline slurry will take place.
Study NCT05583058 — intervention group
Intervention type: OTHER
Intervention: Hormone Overdose and Misuse
Description: This is an observational study. Hormone Overdose and Misuse is an exposure.
Study NCT05047627 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone-Based Digital Intervention
Description: The digital intervention will be a prototype, and the current trial will be used to continue to both develop and refine the intervention. The current intervention will be based on a combination of cognitive-behavioral principles. As with prior research, the mobile platform will be delivered via Qualtrics, a HIPAA compliant and mobile-friendly platform. The cognitive-behavioral therapy will be primarily based on components with strongest support in digital interventions. The app will continuously collect passive sensing data on patterns in 1) sleep duration and quality;(2) light (3) location; (4) movement (5) social contact including duration and frequency of incoming and outcoming calls and text messages; (6) screen time; and (7) heart rate variability; (8) sound levels captured through passively collected smartphone The platform will deliver interactive interventions where participants will view texts and images, and it will also allow user interaction.
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fianlimab
Description: Administered intravenously (IV) every 3 weeks (Q3W)
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cemiplimab
Description: Administered IV Q3W
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: IV Infusion, Q3W
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: IV Infusion, Q3W
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: IV Infusion, Q3W
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV infusion, Q3W
Study NCT04306315 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Brodalumab
Description: Brodalumab is an anti-IL-17 receptor antibody, which blocks the inflammatory effects of IL-17 in the skin.
Study NCT04306315 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Brodalumab
Description: Brodalumab is an anti-IL-17 receptor antibody, which blocks the inflammatory effects of IL-17 in the skin.
Study NCT06566313 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: transcranial Direct Current Stimulation
Description: On the basis of conventional anti-PD drugs, the left M1 region (based on the C3 coordinates of EEG 10-20 system and the surrounding FC1, FC5, CP1, CP5 coordinates) was treated with cathodic tDCS. The electrical stimulation intensity was 2.0mA, the treatment time was 20min, and the treatment lasted for 10 days.
Study NCT06160713 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole 65 MG
Description: Two capsules of suba-itraconazole 65 mg twice daily for 6 months
Study NCT06160713 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: Standard care for bronchiectasis
Study NCT06160713 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: Standard care for bronchiectasis
Study NCT05523687 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-PC14586
Description: Single, oral dose of \[14C\]-PC14586
Study NCT05800015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: IV infusion, Q3W
Study NCT05669885 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants will be allocated to receive oral administration of placebo.
Study NCT05744232 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low calorie total diet replacement
Description: Summary~1. Weeks 1-12: TDR phase~2. Weeks 13-14: Food reintroduction phase I~3. Weeks 15-16: Food reintroduction phase II~4. Weeks 17 till 20: Food reintroduction phase III~5. Weeks 21 till 24: Maintenance phase
Study NCT05744232 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: Participants allocated to the control group will be offered and continue benefiting from standard care. Participants will not be stopped from pursuing any behavioural weight management programme but if they do, this will be recorded.
Study NCT05931458 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Appendectomy
Description: Laparoscopic appendectomy is a relatively simple surgical procedure that can be performedby most surgeons, either on an outpatient basis or with a single-night hospital stay. The laparoscopic approach is now the recommended option due to faster recovery times and fewer wound complications.
Study NCT05931458 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Infliximab
Description: Administration of Infliximab (Anti-TNF-a biologic drug)
Study NCT05860400 — intervention group
Intervention type: BEHAVIORAL
Intervention: Healthy life style
Description: Healthy diet, regular exercise, and quitting smoking
Study NCT05860400 — intervention group
Intervention type: DRUG
Intervention: Secondary prevention for atherosclerotic coronary artery disease
Description: Antiplatelet therapy, as well as medications for control of heart rate, blood pressure, low-density lipoprotein cholesterol, and blood glucose
Study NCT05860400 — intervention group
Intervention type: DRUG
Intervention: Immunosuppressive therapy
Description: Glucocorticoids and/or immunosuppressive agents
Study NCT05860400 — intervention group
Intervention type: PROCEDURE
Intervention: Coronary revascularization
Description: Percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG).
Study NCT05860400 — intervention group
Intervention type: DRUG
Intervention: Supportive therapies
Description: Medical interventions for prevention and treatment of the side effects of the above treatment, such as abnormal liver function, hypocalcemia, hypokalemia, peptic ulcer, infection, et al.
Study NCT05516966 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS9531
Description: Administrated SC
Study NCT06397339 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: INTACT Program
Description: The INTACT Program has three components:~1. provide a training for Primary Care Providers (PCPs) training in screening, diagnosis, and care for ADRD,~2. at the PCP level, provide quarterly webinars. Topics will address driving and dementia; communication tips for someone with dementia; eating and drinking in advanced dementia; and advanced care planning for dementia.~3. At the clinic level, provide a workflow model for cognitive evaluation and setting a plan for the newly diagnosed patient. The INTACT intervention lasts 12 months and Continuing Medical Education credits will be available to PCPs who complete the INTACT training program
Study NCT06397339 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: INTACT Program
Description: The INTACT Program has three components:~1. provide a training for Primary Care Providers (PCPs) training in screening, diagnosis, and care for ADRD,~2. at the PCP level, provide quarterly webinars. Topics will address driving and dementia; communication tips for someone with dementia; eating and drinking in advanced dementia; and advanced care planning for dementia.~3. At the clinic level, provide a workflow model for cognitive evaluation and setting a plan for the newly diagnosed patient. The INTACT intervention lasts 12 months and Continuing Medical Education credits will be available to PCPs who complete the INTACT training program
Study NCT05613972 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Brief Suicide and Trauma Therapy
Description: 12-week trauma therapy
Study NCT05516966 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Administrated SC
Study NCT06183892 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus Sustained-release Capsules
Description: Immediate-release tacrolimus for at least 3 months after liver transplantation, and then convert to tacrolimus sustained-release capsules at a ratio of 1:1 to 1:1.2; Take the medicine once a day on an empty stomach in the morning.~(The specific medication plan is decided by the clinician according to the actual situation)
Study NCT05219799 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Propranolol Hydrochloride
Description: Regional forearm blockade of β-adrenergic receptors at 20 mcg/dL/min via brachial artery catheter during normoxia and hypoxia exposures
Study NCT05219799 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Isoproterenol
Description: Dose response (1, 3, 6, and 12 ng/dL/min) regional infusion to assess β-adrenergic receptor responsiveness
Study NCT05219799 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Phentolamine Mesylate
Description: This infusion will be for 10 min before baseline measurement (12 mcg/dL/min) and continue the infusion at a maintenance rate (5 mcg/dL/min).
Study NCT05219799 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Norepinephrine
Description: Regional forearm infusion at 8 ng/dL/min via brachial artery catheter during normoxia and hypoxia exposures
Study NCT05516966 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dulaglutide Injection
Description: Administrated SC
Study NCT05399134 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Modified Functional Foods
Description: Subjects will be provided with ABREP-fortified bread, microfluidic co-flow noodles, and 5ibrePlus™-fortified white rice served in a mixed meal.~ABREP-fortified bread: Anthocyanins are known to exert anti-diabetic effects through modulating digestion, glucose uptake, insulin secretion and sensitivity. Moreover, inhibitory effects of anthocyanins on various carbohydrases, including a-glucosidase and a-amylase have been widely reported.~Microfluidic co-flow noodles: Microfluidic technology is employed to design noodle-food structures consisting of a mix of soy protein isolate and alginate as gelling agents to offer a type of novel noodles with proteins and negligible carbohydrate content.~5ibrePlus™-fortified white rice: 5ibrePlus™ is a patented novel fibre grain product by Alchemy Foodtech Pte. Ltd (WO 2017/142477) with reduced GI. Its main constituents are insoluble resistant starch and soluble fibre.
Study NCT05399134 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control Functional Foods
Description: Subjects will be provided with control function foods including white bread, beehoon noodles, and jasmine white rice served in a mixed meal.
Study NCT05977491 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Health care practitioner is informed of POCT results for CT and NG
Description: Molecular, PCR based near-POCT performed by the research assistant on self -collected urine. The outcome is positive or negative