AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05624073 — intervention group
Intervention type: DEVICE
Intervention: LarySealTM Pro
Description: The LarysealTM Pro is the new generation mask for safe and effective airway management, as it could reduce the risk of aspiration by the integrated suction catheter port to allow effective removal of fluids and gastric contents. So that, it could be a promising airway device as its symmetrical cuff and tube contoured to match the oropharyngeal anatomy for quick and easy first time insertion success. It could be applied in both routine and advanced airway management for patients with a higher risk of a difficult airway, unexpected intubation difficulties, beside to airway control during anesthesia. It was presented in the clinical market in: sizes 3, 4 and 5 (according to the body weight; size 3: 30-50Kg, size 4: 50-70 Kg, and size 5:70-100Kg) that can accept larger tracheal tube up to 7.5 and 8mm inner diameter respectively with maximum suction catheter size of 16 Fr. Both devices accommodated standard conventional endotracheal tubes for intubation.
Study NCT05164458 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI 389 Injection
Description: IBI 389 IV Q2\~Q3W Day 1
Study NCT04948697 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT1706
Description: 15 mg/kg intravenously once every 3 weeks (dosed in 21-day cycles)
Study NCT06008782 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: HEARS-SLP device
Description: Tailored fitting and programming of a personal sound amplifier. This will be accompanied by a component of aural rehabilitation.
Study NCT06008782 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HEARS-SLP device
Description: Tailored fitting and programming of a personal sound amplifier. This will be accompanied by a component of aural rehabilitation.
Study NCT05766176 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: COVID-19 Antibody
Description: This descriptive study examines the levels of neutralizing antibodies against COVID-19 in health workers before and after the Quantitative Anti-SARS-CoV-2 Test is an examination to measure in vitro quantitative antibodies (including IgG) against the receptor binding domain (RBD) of the SARS-CoV Spike (S) protein. -2, which aims to assess the adaptive humoral immune response to the SARS-CoV-2 Spike protein. Measurement with the ECLIA method. Ratio Scale after the 2nd booster COVID-19 vaccine in Surakarta, Indonesia.
Study NCT05249569 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Axitinib
Description: Axitinib to be administered orally BID
Study NCT05249569 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avelumab
Description: Avelumab to be administered as a 1-hour IV infusion on Day 1 and Day 15 of each 28-day cycle.
Study NCT05249569 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bavituximab
Description: Bavituximab to be administered weekly on Days 1, 8, 15 and 22 of the 28-day cycle.
Study NCT06008782 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: HEARS-SLP program
Description: Tailored aural rehabilitation for participant and communication partner
Study NCT06008782 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HEARS-SLP program
Description: Tailored aural rehabilitation for participant and communication partner
Study NCT06361381 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)
Description: Both concha will be swabbed with an alcohol wipe before applying a thin layer of conductive gel. An ear clip electrode will be placed in the concha of both ears.~A frequency of 25 Hz will be applied with a pulse duration of 200 µs. Every 5 minutes, the subject will be asked if the intensity can be increased, decreased or remain the same to maintain the same level of intensity. Participants will also receive active TENS, 100 Hz, 200 µsec on forearm.
Study NCT06361381 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)
Description: For placebo TaVNS, the intensity will be increased to a sensory level and then decreased to 0 mA. Participants will also receive active TENS, 100 Hz, 200 µsec on forearm.
Study NCT06361381 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Nerve Stimulation
Description: TENS will be applied on subject's forearm at a strong but comfortable intensity
Study NCT06361381 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Transcutaneous Electrical Nerve Stimulation
Description: TENS will be applied on subject's forearm at a strong but comfortable intensity
Study NCT06303791 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Psychosocial intervention
Description: The psychosocial program with digital support has been developed by combining different theoretical perspectives on intervention in children with ASD without intellectual disabilities and children with ADHD. The contents of the program are based on three main approaches, each of which has separately demonstrated evidence in the treatment of these neurodevelopmental disorders: psychoeducation and stress management, cognitive behavioral techniques, and techniques in social and communication skills (Dahl et al., 2020; DuPaul et al., 2020; Tan-MacNeill et al., 2021).
Study NCT04950777 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: patient education document
Description: The patient education will be designed to address and investigate the four domains of physical literacy including, knowledge and understanding, motivation and confidence, daily behavior, and physical competence, (i.e., referral based training/PT (passive), self-motivated/directed exercise choice (speaks to child ownership/motivation), simple play outside 60 minutes/day (middle)).
Study NCT05644782 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Open wheat challenge
Description: Patients randomized to intervention diet group will have to follow a diet with elimination of wheat and cow's milk products for 2 months; after that they will be exposed to an open wheat challenge, with reintroduction of wheat. After 2 weeks of open diet, or whenever dermatologic, intestinal and/or extraintestinal symptoms should return or intensify, all patients will be revaluated and will end the study.
Study NCT05644782 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo challenge
Description: Patients randomized to control diet group will have to follow a diet with elimination of rice and turkey's meat products for 2 months; after that they will crossover to a wheat and cow's milk products free diet and, finally, after 2 months, they will be exposed to an open wheat challenge, with reintroduction of wheat. After 2 weeks of open diet, or whenever dermatologic, intestinal and/or extraintestinal symptoms should return or intensify, all patients will be revaluated and will end the study.
Study NCT05514301 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sensitivity of Polydeep vs high experienced endoscopists for colorectal polyp detection
Description: Both diagnostic interventions will be performed in all patients~1. High definition colonoscopy performed by high experienced endoscopists blinded to Polydeep.~2. Polydeep: a CADe and CADx system. The gold standard will be the histological diagnosis of the lesion.
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10% lidocaine spray
Description: 10% lidocaine spray 3 puff for the throat before induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of lidocaine spray
Description: Normal saline spray 3 puff for the throat before induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo of lidocaine spray
Description: Normal saline spray 3 puff for the throat before induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisatracurium
Description: Intravenous cisatracurium 0.12 mg/kg during induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo of cisatracurium
Description: Intravenous normal saline during induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of cisatracurium
Description: Intravenous normal saline during induction
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: The dosage of intravenous propofol for the first subjects was predetermined for each arm, and the dosage for the subsequent subjects would be determined according to the response of the previous subjects using the Dixon's up-and-down method with a step size of 0.25 mg/kg. If the subjects had no movement and stable hemodynamic status during and after the laryngeal mask airway (LMA) placement, the predetermined dosage of propofol for the subsequent subject would be decreased by 0.25 mg/kg. On the other hand, if the subjects had obvious movement, failure to LMA placement, and significant hemodynamic changes, the predetermined dosage of propofol for the subsequent subject would be increased by 0.25 mg/kg.
Study NCT05310110 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Propofol
Description: The dosage of intravenous propofol for the first subjects was predetermined for each arm, and the dosage for the subsequent subjects would be determined according to the response of the previous subjects using the Dixon's up-and-down method with a step size of 0.25 mg/kg. If the subjects had no movement and stable hemodynamic status during and after the laryngeal mask airway (LMA) placement, the predetermined dosage of propofol for the subsequent subject would be decreased by 0.25 mg/kg. On the other hand, if the subjects had obvious movement, failure to LMA placement, and significant hemodynamic changes, the predetermined dosage of propofol for the subsequent subject would be increased by 0.25 mg/kg.
Study NCT06407466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: taping
Description: Kinesiology taping; In order to facilitate the muscle, while the subject is standing and his body is flexed to ensure hip flexion, both I bands will be applied from the origin to the insertion, with 30% stretching from the medial and lateral, starting from the Ischial Tuberositas to the border of the Popliteal Fossa.
Study NCT06407466 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The routine training program will continue without intervention.
Study NCT06407466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mobilization
Description: Instrument-assisted soft tissue mobilization; The subject is in a prone position on a bed, with the lower extremity in a neutral position, and a hazelnut-sized amount of lubricant will be applied to the working surface, and will be applied to the skin on the back of the upper leg for 5 minutes, targeting the tissue structures. (Hamstring and deep fascia covering this muscle) Pressure and speed will be adjusted according to the subject's tolerance so as not to cause pain.
Study NCT06045039 — intervention group
Intervention type: OTHER
Intervention: Stent-balloon-stent (SBS) technique
Description: Patients with coronary bifurcation lesions underwent stent-balloon-stent (SBS) technique. The procedure of this technique is to implant the stent into the side branch at the 1\~2mm, which is away from the opening of the branch, and then implant the stent into the main vessel. The guide wire enters the side branch from the mesh at the distal end of the main vascular stent, and the drug balloon is used to dilate the opening of the side branch, so that the opening area of the side branch is more than 5mm².
Study NCT04686864 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support Group for Caregivers
Description: Engage parents in the community via this support group, so they can be supported by other parents who know the system, can advise them on how to proceed, and empower them to help their children. Parents will learn psychoeducation about eating disorders and how to support their children.
Study NCT06332118 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ice massage group
Description: Measurement surveys will be applied to obtain pre-test data from hemodialysis patients who meet the research criteria. After the preliminary test data are obtained, ice cubes prepared by the researchers before the needle insertion into the arteriovenous fistula for the hemodialysis procedure will be wrapped in a thin sponge and an ice massage will be applied to the needle insertion area of the patient in a direction that will not disrupt the circulation. This process will take approximately 3-5 minutes or the massage will be terminated when the patient feels drowsiness. In the next stage, the patient will undergo needle intervention for hemodialysis. At the end of this stage, the patient's pain will be evaluated. Patients will be re-evaluated at 24, 48 and 72 hours for ecchymosis and hematoma and relevant measurements will be provided.
Study NCT05334433 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthesia injection
Description: Local anesthesia administration
Study NCT05334433 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Local anesthesia injection
Description: Local anesthesia administration
Study NCT05699083 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Body Image/Self-Esteem Questionnaires
Description: Pre-operation and post-operation questionnaires to assess factors including but not limited to body image, quality of life, and self-esteem.
Study NCT05272982 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Thoracic fluid content by electrical cardiometry group
Description: Thoracic fluid content will be measured using electrical cardiometry device (ICON ® Cardiotronics, Inc., La Jolla, CA 92307; Osyka Medical GmbH, Berlin, and Germany, model C3, Serial no: 1725303). The ICON device will be connected to four electrocardiogram electrodes which will be placed over patients' skin after cleaning with alcohol at the neck below the left ear, just above the left clavicular midpoint, and two electrodes at left mid-axillary line one at the level of the xiphoid process, and the other electrode 5 cm below this point. The thoracic fluid content will be observed for 30 s and the average of the highest and lowest values will be recorded.
Study NCT05272982 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound examination group
Description: The 12-region technique for lung assessment will be performed using Philips ® (CX50 - Extreme edition) equipped with phased array transducer. B-line will be defined as laser like vertical hyperechoic artefact which extends between the pleural line and the bottom of the screen and moves with respiratory movements. Two types of B-lines will be evaluated.
Study NCT05873465 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sedation with Midazolam, Fentanyl, and Propofol
Description: Patients will have teeth extracted under sedation with Midazolam, Fentanyl, and Propofol
Study NCT05873465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sedation with Midazolam, Fentanyl, and Propofol
Description: Patients will have teeth extracted under sedation with Midazolam, Fentanyl, and Propofol
Study NCT05873465 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extraction of teeth
Description: The necessary teeth will be extracted
Study NCT05873465 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraction of teeth
Description: The necessary teeth will be extracted
Study NCT05090111 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALG-055009
Description: Single or multiple doses of ALG-055009
Study NCT05090111 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Single or multiple doses of Placebo
Study NCT06381947 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipid-lowering therapy combination with PCSK9 inhibitors, bempedoic acid and ezetimibe
Description: Evaluation of therapy of bempedoic acid with PCSK9 inhibitors and ezetimibe in reducing LDL-C in statin-intolerant patients.
Study NCT06381947 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipid-lowering therapy combination with PCSK9 inhibitors and ezetimibe
Description: Evaluation of therapy of PCSK9 inhibitors with ezetimibe in reducing LDL-C in statin-intolerant patients.
Study NCT06448520 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Power Sprint Test
Description: The Muscle Power Sprint Test (MPST) is an easy-to-perform field test of anaerobic capacity for children and adolescents. The only necessities for the administration of this test are an open space, a stopwatch and two cones or lines. Test subjects are encouraged to perform six 15-meter sprints at a maximal pace between the two cones/lines, with a 10-second rest in between each effort. The distance covered during these short runs corresponds well to the distances children cover during daily play activities. The power that is generated with each sprint can be calculated using the formula: power = (total mass x 15 m²)/time³.
Study NCT05524376 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study NCT06329245 — intervention group
Intervention type: OTHER
Intervention: Do not take any interventions
Description: Do not take any interventions
Study NCT05913895 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: hydrogen water
Description: To investigate whether the intervention of hydrogen water adjuvant therapy can improve oral mucositis, oral frailty, pain and Quality of Life with head and neck cancer who have received radiation therapy or combined chemotherapy.
Study NCT05913895 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hydrogen water
Description: To investigate whether the intervention of hydrogen water adjuvant therapy can improve oral mucositis, oral frailty, pain and Quality of Life with head and neck cancer who have received radiation therapy or combined chemotherapy.
Study NCT05804539 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Manual therapy
Description: The therapist checks the range of motion of the cervical joints and gives manual treatment to the restricted joints. Throughout the examination, the subject lied in a supine position on a professional rehabilitation bed with the seventh cervical vertebra (C7) on the edge of the bed and the other the body above the C7 were placed off the bed. The therapist held the subject's occipital bone with one hand and the radial aspect of the second metacarpophalangeal joint of the other hand to grip the spinous process of the sixth cervical vertebra and slowly pushed the occiput downward to check the joint mobility of the fifth cervical vertebra and the sixth cervical vertebra. After the examination, the restricted joint was accurately located and treated with targeted manual therapy. For example, stretching was performed with the right side of C4-C5 flexed, closing only the right side of the subject's C4-C5 as much as possible to increase joint mobility on the right side of C4-C5.
Study NCT05804539 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi
Description: Based on the characteristics of young people and the need to correct their FHP, the classic Yang's 24 Forms of Tai Chi has been improved. The movements are mostly upper limb movements and the lower limb movements have been simplified to make the movements easy to learn. The modified Tai Chi exercise retains the traditional Tai Chi movements but is simple and easy to learn; at the same time, it increases the movement of the shoulder and neck joints. The subjects performed each exercise session in a group setting at the school gymnasium, with a professional Tai Chi instructor guiding them through a warm-up session, followed by a Tai Chi exercise session.
Study NCT05804539 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi and Manual therapy
Description: Intervention content of MSG included 15-min Tai Chi exercise and 15-min manual therapy, with the order of intervention being Tai Chi exercise first and then manual therapy.
Study NCT05000034 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Weaning protocol
Description: Application of a weaning protocol from the mechanical ventilation
Study NCT05534620 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: IV infusion
Study NCT05534620 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: IV infusion
Study NCT06081478 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD19/CD22-bispecific CAR-T cells
Description: CD19/CD22-bispecific CAR-T cells were infused at the same day with 2×10e6/kg and 1×10e6/kg dosage, respectively.
Study NCT05962073 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HFNC
Description: High-flow oxygen therapy before intubation for preoxygenation
Study NCT05737108 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Bilberry capsule product
Description: A specific bilberry capsule product, containing bilberry dried extracts at 23.2 mg and bilberry powder at 3.2 mg will be given to participants for oral intake for 30 days. 30 days of Bilberry capsule product or placebo with crossover to the other.
Study NCT05737108 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bilberry capsule product
Description: A specific bilberry capsule product, containing bilberry dried extracts at 23.2 mg and bilberry powder at 3.2 mg will be given to participants for oral intake for 30 days. 30 days of Bilberry capsule product or placebo with crossover to the other.
Study NCT05737108 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo(starch)
Description: 30 days of placebo or Bilberry capsule product with crossover to the other.
Study NCT05737108 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo(starch)
Description: 30 days of placebo or Bilberry capsule product with crossover to the other.
Study NCT06432023 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance imaging
Description: Diagnostic and research scanning using magnetic resonance imaging.