AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06024785 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vertebropexy
Description: microsurgical (i.e., the use of a microscope or magnifying glasses during decompression) lumbar laminotomy with partial removal of the medial facet joint by preserving the midline structures (supraspinous-interspinous ligament complex); approach: bilateral or ipsilateral with cross-over to the contralateral side. Additional stabilization of the spine with a ligament (for instance semitendinosus donor allograft), which connect the postoprior structures (Proc. Spinosus and/or Lamina) of the vertebrae . Situation-related application of laminar bands or analogous suture material (for instance FiberTape, Arthrex, Naples or Nile Band, K2M, Virginia)
Study NCT04751253 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Intensity Laser Therapy
Description: different doses of energies of high-intensity LASER on pain and functional activity in patients with chronic knee OA.
Study NCT04751253 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: High Intensity Laser Therapy
Description: different doses of energies of high-intensity LASER on pain and functional activity in patients with chronic knee OA.
Study NCT06309771 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stress management, sleep improvement and fatigue reduction, sedentary behaviors reduction and physical activity promotion.
Description: The study seeks to quantify the impact of a complex intervention based on 3 modules :~1. Stress management~2. Sleep improvement and fatigue reduction,~3. Sedentary behaviors reduction and physical activity promotion.~Students from the interventional group will follow these 3 different health-related modules in a random order (6 predetermined order). Each module will be composed on 3 sessions. Each session includes individual interviews covering initial assessment and personalized goal setting.
Study NCT06337929 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CAPOEIRA TRAINING
Description: The protocol of the capoeira training program and the movements (blows, dodges and flourishes) will be based on the Capoeira Abadá method.
Study NCT06337929 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CONTROL GROUP
Description: The protocol of the control group will be based on an intervention with capoeira movements, however, without important cardiovascular, neuromuscular and metabolic demands, being an activity with stretching movements from positions of the capoeira modality itself.
Study NCT05718622 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: real EECP
Description: Real EECP treatment is delivered 45min per day for 14 sessions continuously. The treatment pressure sets at 150 millimeters of mercury.
Study NCT05718622 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham EECP
Description: Sham EECP treatment is delivered 45min per day for 14 sessions continuously. The treatment pressure sets at 75 millimeters of mercury.
Study NCT05746338 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ring-type wearable device
Description: The ring-type wearable device is a slim, lightweight smart ring that continuously tracks blood oxygen saturation and heart rate throughout the day.
Study NCT05746338 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Overnight polysomnography
Description: Overnight polysomnography is the gold standard for diagnosing OSAS.
Study NCT05851976 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naproxen
Description: Naproxen 500mg twice daily for 16 days
Study NCT05851976 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Naproxen
Description: Naproxen 500mg twice daily for 16 days
Study NCT05851976 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Duloxetine
Description: Duloxetine 60mg daily for 14 days
Study NCT05292079 — intervention group
Intervention type: DEVICE
Intervention: CAPTURER
Description: Patients in whom treatment with (CAPTURER) has been attempted
Study NCT05995964 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07275315
Description: subcutaneous injection
Study NCT05995964 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07264660
Description: subcutaneous injection
Study NCT04566744 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fRMI
Description: The measurements performed will be the participant's brain activity, as well as behavioral measurements associated with the tasks performed (response time, correctness of the response). Brain activity measurements will be performed on the Siemens 3T system of the MRI department of CERMEP. The subject will perform the task under study while the level of brain activity is recorded. The functional examination will be subdivided into several parts according to its total length in order to spare the subject. The total duration of MRI acquisitions will be approximately 1 hour regardless of the axis.
Study NCT05788406 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Short foot exercises, Dynamic balance exercises and insole
Description: Short foot exercises is used to improve muscle strenght, Dynamic balance exercises is used to improve balance and insole is used to improve MLA
Study NCT05903573 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: The intervention group will receive cognitive training that provides specific training tasks directed at essential cognitive domains tied to the project's aims and hypotheses (processing speed and working memory) that correspond with the neurocognitive and functional neuroimaging measures to be studied.
Study NCT05903573 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Computerized Cognitive Stimulation
Description: Participants will complete cognitively-stimulating computer activities. The duration is 60 min/day; the frequency is two to three days/wk, for 16 weeks with the goal of completing 40 sessions.
Study NCT06361914 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital CBT-I
Description: Sleep restriction includes behavioral instructions to limit the time spent in bed to increase sleep drive and further reduce time awake in bed.~Stimulus control therapy entails behavioral instructions to strengthen the association between bed and sleep and to eliminate conditioning of non-sleep behavior and bed.~Deactivation/relaxation training involves methods to reduce somatic tension and limit intrusive thought processes that interfere with sleep.~Cognitive therapy helps to identify, challenge, and modify dysfunctional beliefs about sleep.~Sleep hygiene education entails specific information relating to lifestyle and environmental factors that may interfere with or promote sound sleep. Sleep hygiene education also includes specific sleep facilitating recommendations, such as avoiding visual access to a clock in the bedroom, regular sleep scheduling, avoiding long daytime naps, and limiting alcohol, caffeine, and nicotine intake.
Study NCT06361914 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Digital Sleep hygiene education
Description: Sleep hygiene education entails specific information relating to lifestyle (diet, exercise, substance use) and environmental factors (light, noise, temperature) that may interfere with or promote sound sleep. Sleep hygiene education also includes specific sleep facilitating recommendations, such as avoiding visual access to a clock in the bedroom, regular sleep scheduling, avoiding long daytime naps, and limiting alcohol, caffeine, and nicotine intake.
Study NCT05118308 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transjugular hepatic venous pressure gradient measurement with liver biopsy
Description: This procedure will be performed by an experienced interventional radiologist who will be supported by a radiology technician and nurse. Transjugular hepatic venous pressure gradient measurement will be performed using standard procedure. Following this, a transjugular liver biopsy will be obtained using an 18-gauge transjugular liver biopsy needle.
Study NCT05118308 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
Description: A linear echoendoscope is inserted with the patient under conscious sedation. Using a through the scope 25-gauge needle connected to a digital manometer, portal and hepatic veins will be punctured under EUS guidance from a trans-gastric/hepatic approach. Following this, EUS-Liver biopsy is then performed immediately following EUS-PPG using a 19-gauge fine needle biopsy (FNB).
Study NCT06369987 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Deleficon A (multifocal)
Description: Daily disposable silicone hydrogel contact lenses indicated for presbyopia, in addition to myopia or hyperopia.
Study NCT06369987 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senofilcon A (multifocal)
Description: Daily disposable silicone hydrogel contact lenses indicated for presbyopia, in addition to myopia or hyperopia
Study NCT06554366 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GentleWave
Description: Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the GentleWave procedure will be performed
Study NCT06554366 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EdgePro laser irrigation
Description: Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the EdgePro procedure will be performed
Study NCT06554366 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Irrisafe passive ultrasonic irrigation
Description: Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the passive ultrasonic irrigation procedure will be performed
Study NCT06168175 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium lactate
Description: 2 mmol/kg, intravenous, daily for 5 consecutive days
Study NCT06168175 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: intravenous, daily for 5 consecutive days
Study NCT05488314 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capmatinib
Description: Capmatinib will be administered orally.
Study NCT05488314 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amivantamab
Description: Amivantamab will be administered as IV infusion.
Study NCT05564052 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibrutinib
Description: Ibrutinib capsules will be administered orally.
Study NCT05564052 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide capsules will be administered orally.
Study NCT05564052 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Rituximab will be administered IV.
Study NCT05995964 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: subcutaneous injection
Study NCT04842448 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyperbaric oxygen
Description: Hyperbaric oxygen 240 kPa for 90 minutes (with 10 min compression time, 2 air bakes and 10 minutes decompression time).
Study NCT04842448 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham treatment
Description: Sham treatment 134-120 kPa Air (with 5 min compression time, and 5 min decompression to 120 kPa, two air brakes will be reported to the subjects)
Study NCT05762796 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS in Youth with mild traumatic brain injury
Description: The safety and tolerability of tDCS have been established in children with mTBI (1). A recent study of 13-18 year youths post-mTBI showed that three sessions of 1.5 mA anodal tDCS over the left DLPFC, positively influenced prolonged working memory deficits. (2) Additionally, rodent studies show the effectiveness of tDCS in improving cognitive-motor (motor planning and balance/gait) function in rats with mTBI. (3)
Study NCT06195072 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlitelimab
Description: IP will be administered subcutaneously by the Investigator or designee as follows:~* Amlitelimab or~* Matching placebo
Study NCT06195072 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: Study participants will take the active investigational product BI 1015550 or matching placebo provided as film-coated tablets, administered orally BID.
Study NCT06195072 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: see Experimental Arm intervention description
Study NCT06234124 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Variable Friction Shoe Training
Description: The experimental group (A) will be given a pair of VF shoes and instructed to use shoes on both feet. This group will be instructed to walk on hard surfaces to engage auditory feedback of the VF shoes. This group group will be monitored daily using actigraphy and will receive weekly check-up telephone calls by a member of the research team to record number of steps, walking time, a scale for self-identified effort and perceived safety levels.
Study NCT06234124 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ankle Foot Orthosis (AFO) Training
Description: The control group (B) will be provided an AFO to use on the paretic limb. This group will be instructed to walk on hard surfaces. This group group will be monitored daily using actigraphy and will receive weekly check-up telephone calls by a member of the research team to record number of steps, walking time, a scale for self-identified effort and perceived safety levels.
Study NCT05368714 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Economic Empowerment (EE)
Description: EE will be provided via a child development account (CDA). CDAs provide children with basic financial education, introduce them to formal financial institutions, and incentivize them to save by matching their deposits. Any of the child's family members, relatives, or friends will be allowed and encouraged to contribute towards the CDA. The account will be matched with money from the program. The maximum family contribution to be matched by the program will be an equivalent of US $10 per month per family or US $120 for the 12-month intervention period.
Study NCT05368714 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multiple Family Group based Family Strengthening (MFG-based FS)
Description: MFG-based FS approach is a family-centered, group delivered, evidence-informed, strength-based intervention designed for children and adolescents whose families struggle with poverty and associated stressors. MFG is based on building support for parents and families by providing opportunities for parents and children to communicate in a safe setting with other families who have shared experiences. The core components of MFG are known as 4Rs and 2S's: rules, responsibility, relationships, respectful communication, stress and social support. Participants in this study arm will receive 16 session of MFG-based FS sessions, delivered by delivered by trained Community Health Workers and Parent Peers.
Study NCT05368714 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EE plus MFG-based FS
Description: EE plus MFG-based FS directly addresses both the economic needs and mental health functioning. It will consists of an EE intervention that comprises a family monetary savings program using CDAs, and a family-based dialogue and training via MFG focused on strengthening family relationships and mental health challenges.
Study NCT05564052 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Bortezomib will be administered either intravenously or subcutaneously.
Study NCT05838300 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Warm humidified CO2
Description: Participants will receive warm (37°C) and humidified (95%) CO2.The humidification and warming device to be used is AlwaysPneumo® AP 50/30 InsuflowPort® (Lexion Medical, FDA approved) which is a specialized port that delivers warmed (95° F) and humidified (95% relative humidity) CO2, the source of which is a standard CO2 tank or wall source
Study NCT05838300 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dry CO2
Description: Participants will receive standard cold (19-21 °C) and non-humidified (0%) CO2 insufflation with Airseal Insufflator
Study NCT05798520 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BIIB091
Description: Administered as specified in the treatment arm.
Study NCT05798520 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DRF
Description: Administered as specified in the treatment arm.
Study NCT05798520 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRF
Description: Administered as specified in the treatment arm.
Study NCT05798520 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Administered as specified in the treatment arm.
Study NCT05798520 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Administered as specified in the treatment arm.
Study NCT04993352 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection
Description: 0.05mL (12.5mg/0.5mL/vial) HLX-04-O solution at a 4-week interval for intravitreal injection
Study NCT06133621 — intervention group
Intervention type: OTHER
Intervention: dosage dRVVT
Description: Blood test dRVVT assay on two tubes of blood in the haemostasis laboratory of the Center de Biologie et de Pathologie Est
Study NCT05479175 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen
Description: Ibuprofen
Study NCT05479175 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Diode laser
Description: Diode laser
Study NCT05479175 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nonactive Diode laser
Description: Nonactive Diode laser
Study NCT04725175 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIPE-307
Description: Single and multiple ascending oral doses of PIPE-307 tablets
Study NCT04725175 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: Single and multiple ascending oral doses of matching Placebo tablets
Study NCT06645106 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rapid Point of Care (POC) Syphilis testing
Description: Participants will undergo the point of care (POC) FDA cleared syphilis health check (SHC) POC test by a research staff using 50 microliters or 1-3 drops of whole blood via finger stick. The analyzer is handheld, and all testing equipment is temperature stable and does not need refrigeration. The SHC-Syphilis results will be available within 10 minutes of receipt given the published turnaround time to results of 15 minutes per package insert and will be recorded as a research note in the electronic medical record (EMR) while the provider assigned to the patient and the Houston Health Department will be notified of results and further treatment will be done if results are positive.
Study NCT05874479 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active PAC
Description: The active PAC will contain HEPA filters inside the device.
Study NCT05874479 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham PAC
Description: The sham PAC will contain no HEPA filters inside the device.
Study NCT06455774 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Wearable Postural Feedback Device
Description: The postural feedback wearable device we will use in the study is programmed to vibrate when hunched postures are detected (based on changes in the curvature and curvature of the spine), alerting users to changes in their body position.
Study NCT06455774 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Trapezius, Sternocleidomastoid (SCM), Scalene, pectoral muscles will be targeted for stretching exercises and deep neck flexors, Trapezius, Levator Scapula, Rhomboids will be targeted for strengthening exercises. The intensity of the exercises will be increased according to the weeks. Stretching exercises will be performed as a single set at the pain limit, maintaining the position of the muscle groups in the longest tolerable position for 30 seconds. In strengthening exercises, participants will hold the position for 5-10 seconds at the end of the movement. Moderate resistance elastic bands and free weights will be used for resistance exercises. In the following weeks, progression will be made in all exercises according to the patient's condition.
Study NCT05839119 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: initial dose is 240 mg administered as two 120 mg (3 mL) injections (SC), followed by subsequent doses at 80 mg (4 mL) administered as one injection (SC)
Study NCT05839119 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Gemcitabine/Cisplatin
Description: SOC Neoadjuvant Chemotherapy: Gemcitabine/Cisplatin 21-day cycles (4 cycles total)~* Gemcitabine: 1000 mg/m2 (IV) Days 1 and 8 of each cycle~* Cisplatin: 70 mg/m2 (if borderline renal function: 35 mg/m2) (IV) Day 1 of each cycle (if borderline renal function, days 1 and 8 of each cycle).
Study NCT06635577 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Verbal Interference Task
Description: During the second half of the study, participants will undergo an interference task such as repetition of the word the; or shadowing a radio broadcast in order to increase cognitive load and disrupt the use of a mental workspace.
Study NCT05036447 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate-Heavy Resistance Exercise
Description: Leg press: 3 x 8 repetitions at 75% of 1 repetition maximum, 3 minutes rest between sets.~Knee extension: 3 x 6 repetitions at 85% of 1 repetition maximum, 3 minutes rest between sets.