AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04784897 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brilacidin
Description: Brilacidin IV infusion
Study NCT04784897 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo IV infusion
Study NCT04784897 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of Care (SoC)
Description: SoC therapies for COVID-19
Study NCT04784897 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard of Care (SoC)
Description: SoC therapies for COVID-19
Study NCT06494215 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Pressure Support Variation and Calculation of Respiratory Mechanics
Description: Patients will be submitted to different levels of pressure support (PS) in a randomly assigned order. First 30 minutes shall be recorded at the clinical PS. Next, blood gas samples shall be collected. Subsequently, three inspiratory pauses of at least 2 seconds shall be performed with an interval of at least 8 respiratory cycles between them. The same shall be performed with three expiratory pauses. Next, the PS shall be varied to 50% less or 50% more than clinical PS (based on randomization) and the same procedures shall be performed after 30 minutes of data recording (blood gas sample collection, inspiratory and expiratory pauses). All data shall be analyzed offline using a software that will be able to compare three different methods to calculate Pendelluft magnitude based on the literature. After completion of the protocol, ventilatory parameters shall be returned to the original settings. If the patient becomes tachypneic during lower PS, the protocol shall be interrupted.
Study NCT05197036 — intervention group
Intervention type: PROCEDURE
Intervention: Total Knee Arthroplasty
Description: A surgical procedure to replace both the tibial and femoral articular surfaces with titanium prostheses.
Study NCT06047847 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: TOTUM-448
Description: The study is divided in two phases. The first clinical phase of the project is aimed at determining TOTUM-448's metabolites absorption peak (two galenic forms will be tested: capsules and powder). Then, human circulating metabolites from polyphenols will be quantified and characterized by ultra-high performance liquid chromatography hyphenated with tandem mass spectrometry (UPLC-MS/MS). Once the absorption profile is characterized, volunteers will visit once again the clinical center for the collection of serum fractions either naïve (before ingestion) or enriched (containing circulating metabolites following TOTUM-448 ingestion). The enriched fraction (circulating bioactive collection) will be collected at t-max as characterized in the first phase (absorption profil's peak). Finally, biological activity of TOTUM-448 on human hepatocytes will be studied by comparing naïve serum and serum containing circulating metabolites according to an in vitro protocol.
Study NCT06235450 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iLIDS100
Description: Subject applies iLIDS accessory to the iTEAR100 device. Applies to Eyelid margin similar to commercial products
Study NCT06210854 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pBI-11
Description: HPV16/18 vaccine
Study NCT06210854 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: pBI-11
Description: HPV16/18 vaccine
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VXB-241 60 mcg (Low Dose)
Description: VXB-241 low dose, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VXB-241 120 mcg (Medium Dose)
Description: VXB-241 medium dose, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VXB-241 240 mcg (Medium-high Dose)
Description: VXB-241 medium-high dose, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VXB-241 480 mcg (High Dose)
Description: VXB-241 high dose, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VXB-241
Description: VXB-241 dose to be decided based on Year-1 results, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo, single, IM injection.
Study NCT06556147 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Arexvy 120 mcg
Description: Arexvy 120 mcg, single, IM injection.
Study NCT06557148 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-Fluoroestradiol PET/CT
Description: Scanned at baseline and again posttreatment within 2 weeks of the restaging FDG PET/CT
Study NCT04291469 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Probiotics（Live combined bifidobacteria, lactobacillus and maltodextrin tables)
Description: The probiotic compound will consist of tables containing approximately 10\^9 colony forming units of the probiotic organisms, Lactobacillus and Bifidobacteria lactis strain，mixed maltodextrin(oral, daily for 14 weeks).
Study NCT04291469 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Prebiotics (Combined inulin and maltodextrin tables)
Description: The prebiotic compound will consist of tables containing inulin and maltodextrin (oral,daily for 14 weeks)
Study NCT04291469 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: maltodextrin
Description: Maltodextrin tables (oral,daily for 14 weeks)
Study NCT06038604 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychosocial Support Intervention
Description: Participants will receive six weekly 60-minute sessions conducted by videoconference.
Study NCT05989802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Oral swab molecular testing
Description: Swab-based testing provides a non-invasive approach to collect respiratory specimens for TB testing. Data in adults suggests that swab-based testing could be valuable when sputum collection is not feasible or available.
Study NCT05989802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Automated Cough Sound Analysis
Description: Cough sounds can be collected through a mobile phone and tablet, and then analyzed with machine learning algorithms to predict TB.
Study NCT05989802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Automated Lung Sound Analysis
Description: Lung sounds can be collected with a non-invasive digital stethoscope, and then saved on a tablet or phone and analyzed by machine learning algorithms to predict TB.
Study NCT05989802 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest X Ray Computer Aided Detection
Description: Several artificial intelligence algorithms have been developed to predict TB, though this has not yet been validated in children.
Study NCT06394596 — intervention group
Intervention type: OTHER
Intervention: Prognostic factors affecting graft survival
Description: The primary outcome measured was a 5-year graft survival, defined as the absence of any need for dialysis or re-transplantation five years following the initial transplantation
Study NCT06473883 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Training recommendation
Description: The players in the intervention group are also given specific training recommendations for the prevention of head injuries, which are compiled by experts (sports scientists, physiotherapists and neuroscientists). The exercise selection covers several areas that can be affected after a head injury. Each section contains 8 different exercises with increasing levels of difficulty (3x Basic-3x Intermediate-2x Advanced). The recommendations should be used as a warm-up program throughout the season before each training session. The coach or athletic coach will lead the warm-up program and ensure that each player follows the sequence and completes each phase according to the scheduled weeks. The warm-up program should be conducted as an 8-week cycle.
Study NCT06333912 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: dental implant placement with ridge splitting.
Description: ridge splitting to increase bone width in atrophic maxilla with simultaneous implant placement
Study NCT06333912 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: dental implant placement with ridge splitting.
Description: ridge splitting to increase bone width in atrophic maxilla with simultaneous implant placement
Study NCT06072053 — intervention group
Intervention type: PROCEDURE
Intervention: Burr Hole Craniostomy and Postoperative Exhaustive Drainage Strategy
Description: According to the preoperative CT results, drilling and drainage was performed at the thickest level of the hematoma; during the operation, the hematoma cavity was adequately flushed with saline and a drainage tube was left in the hematoma cavity; after the operation, the hematoma cavity was flushed with urokinase, and the drainage tube was removed after adequate drainage.
Study NCT06072053 — intervention group
Intervention type: PROCEDURE
Intervention: YL-1 puncture needle and Postoperative Exhaustive Drainage Strategy
Description: Based on preoperative CT, the thickest level of the hematoma was selected and localized. During the operation, an electric drilling needle was used to rapidly break through the skull and dura to enter the cavity of the subdural hematoma, and the puncture needle was fixed to the skull to drain the subdural hematoma. After the operation, the hematoma cavity was flushed with urokinase, and the drainage tube was removed after adequate drainage.
Study NCT05361707 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
Description: Once Daily
Study NCT04873050 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide Pen Injector [Ozempic]
Description: Start injection of semaglutide 0.25mg subcutaneously (SC) once a week for 4 weeks; step up to 0.5 mg SC QD for once a week for 4 weeks to a final dose of 1.0 mg semaglutide SQ weekly for 24 doses
Study NCT04873050 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Placebo semaglutide pen injector
Description: Start injection of placebo semaglutide 0.25mg subcutaneously (SC) one a week for 4 weeks; step up to 0.5 mg SC QD for once a week for 4 weeks to a final dose of 1.0 mg semaglutide SQ weekly for 24 doses
Study NCT05022394 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV
Study NCT05022394 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sapanisertib
Description: Given PO
Study NCT05221905 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BEET IT - Concentrate Beet root juice
Description: Beet It Sport (James White Drinks, Ltd.) each containing 400mg of inorganic nitrate (\~6.5 mmol) will be consumed twice daily (totalling \~13 mmol of inorganic nitrate per day) for at least 2 days prior to testing visits, as well as 2 hours prior to testing visits.
Study NCT05221905 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: BEET IT - Concentrate Beet root juice
Description: Beet It Sport (James White Drinks, Ltd.) each containing 400mg of inorganic nitrate (\~6.5 mmol) will be consumed twice daily (totalling \~13 mmol of inorganic nitrate per day) for at least 2 days prior to testing visits, as well as 2 hours prior to testing visits.
Study NCT05221905 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BEET IT - Concentrate Beet root juice (nitrate depleted)
Description: Beet It Sport (James White Drinks, Ltd.) each containing 0mg of inorganic nitrate (\~0 mmol) will be consumed twice daily (totalling \~0 mmol of inorganic nitrate per day) for at least 2 days prior to testing visits, as well as 2 hours prior to testing visits. It is provided by the same company that produces the concentrated beet root juice shots (James White Drinks) but the placebo version is nitrate-depleted.
Study NCT05221905 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: BEET IT - Concentrate Beet root juice (nitrate depleted)
Description: Beet It Sport (James White Drinks, Ltd.) each containing 0mg of inorganic nitrate (\~0 mmol) will be consumed twice daily (totalling \~0 mmol of inorganic nitrate per day) for at least 2 days prior to testing visits, as well as 2 hours prior to testing visits. It is provided by the same company that produces the concentrated beet root juice shots (James White Drinks) but the placebo version is nitrate-depleted.
Study NCT05793138 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Geriatric Care Model
Description: First, older adults complete the Geriatric screen for OLder adults receiving Dialysis (GOLD), a battery of validated, self-administered geriatric screening instruments, used to identify Geriatric 5M-related problems. Then, a research team with geriatrics expertise leads patient prioritization of GOLD-identified problems in a telehealth visit and provides the dialysis team with guideline-directed, individualized recommendations for geriatric problem management.
Study NCT05793138 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Usual Care
Description: Participants will continue to receive standard of care. Then after 12 months, they will follow the Geriatric Care Model. They will complete the Geriatric screen for OLder adults receiving Dialysis (GOLD), a battery of validated, self-administered geriatric screening instruments, used to identify Geriatric 5M-related problems. Then, a research team with geriatrics expertise leads patient prioritization of GOLD-identified problems in a telehealth visit and provides the dialysis team with guideline-directed, individualized recommendations for geriatric problem management.
Study NCT06419192 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary advice
Description: Eat 7 dates a day from 37 weeks' gestation until delivery. Women will be provided with the quantity of dates they need.
Study NCT06419192 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary advice alone
Description: Advise to eat 7 dates a day from 37SA until delivery. The food will not be provided.
Study NCT06419192 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: food supplied
Description: Eat 7 dates a day from 37 weeks' gestation until delivery. Women will be provided with the quantity of dates they need.
Study NCT06150573 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Test Dentifrice
Description: Dentifrice containing 5% weight by weight (w/w) KNO3, 1% alumina, 5% STP and 1150 ppm fluoride as sodium fluoride.
Study NCT06150573 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Reference Dentifrice (Aquafresh Cavity Protection)
Description: Dentifrice containing 1150 ppm fluoride as sodium fluoride.
Study NCT05471323 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RC1012 injection (allo-DNT cells)
Description: RC1012 injection (allo-DNT cells) from healthy donors and have been proved to be safe and demonstrated potent cytotoxicity against AML blasts from AML patients in preclinical and preliminary clinical studies. Allo- DNT cells will be collected from healthy donors (NO MHC match needed) and injected into patients. The drug for this study is an off-the-shelf product. Patients DO NOT need to wait for the cell manufacturing.
Study NCT06115941 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pre-Op Incentive Spirometer
Description: incentive spirometry group patients were directed to start incentive spirometry, 48 hours prior to surgery. They were given an incentive spirometer and were briefed that they should inhale into the mouth piece of spirometer to lift the balls to the roof of tube and hold for five seconds and then exhale. 13 They were asked to perform 10 such breaths for 6 times in a day till surgery under direct supervision of researcher and this was charted in patient file.
Study NCT04787094 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yoga
Description: Yoga
Study NCT04787094 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Stabilization Exercise
Description: Spinal Stabilization Exercise
Study NCT04749966 — intervention group
Intervention type: OTHER
Intervention: This is an observational study, there are no interventions
Description: This is an observational study, there are no interventions
Study NCT04539795 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alvelestat
Description: oral tablet
Study NCT04575142 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CO2 laser
Description: the CO2 laser (AcuPulse DUO, Lumenis, Yokneam, Israel) generally ranges from 3 to 10 W in superpulse mode, with 0.05 second on/0.01 second off, depending on lesion size and location of the lesion(s).~The CO2 laser can be used in a continuous, pulsed, or superpulsed mode. The superpulsed mode reduces the exposure time to a few nanoseconds while delivering high energies of 400 to 500 W with each peak. The rest time between each peak allows the tissues to cool and reduces thermal injury to adjacent tissues.
Study NCT03966781 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ESWL
Description: ESWL will be conducted under epidural anesthesia. For epidural anesthesia, bupivacaine will be used to block the T6-T12 spinal segments. The patient's eyes will be lightly covered all along the procedure. Once epidural anesthesia is achieved, the patient will be given a light sedation and ESWL will be performed using a Dornier dual focus lithotripsy system providing a maximum of 5000 at the rate of 90 shocks per minute in over 1-2 days.
Study NCT03966781 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ERCP
Description: Once ESWL is over, an endoscopic pancreatic sphincterotomy will be performed and complete stone removal will be attempted with subsequent stenting of the pancreatic duct in the presence of a pancreatic stricture (not detected on MRCP prior to enrolment) or in case of incomplete stone removal
Study NCT03966781 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham ESWL
Description: In the sham/control group, patients will be given a transient superficial pin-prick sensation to give the feel of epidural anesthesia. After that the lithotripsy machine the will be switched on, without establishing any form of contact with the patients body.
Study NCT03966781 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham ERCP
Description: Following sham ESWL patientswill be subjected to sham ERCP to examine the papillary area, but no pancreatic ductal intervention will be performed.
Study NCT05125289 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graston technique group
Description: Moist hot pack (10 minutes) Isometric quadriceps exercises (10 repetitions) Straight leg raise (10 repetitions) Graston technique steps 6 long strokes by the GT1 instrument on the hamstring muscle longitudinally. The Graston technique duration will be 5 minutes
Study NCT05125289 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active release technique group
Description: * Moist hot pack (10 minutes)~* Isometric quadriceps exercises (10 repetitions)~* Straight leg raise (10 repetitions)~ART steps:~* Subject lies on the plinth in prone or in side lying position with the dominant side facing upwards.~* Gentle tension is applied to the hamstring muscle along the entire length while stretching the leg in prone lying or side lying positions, depending on the level of pain and tightness of muscle (5 repetitions at 5 seconds interval).~* Gentle tension is also applied at the origin and insertion of the hamstring muscle until the patient feels full release.
Study NCT05125289 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive Neuromuscular Facilitation stretching group
Description: * Moist hot pack (10 minutes)~* Isometric quadriceps exercises (10 repetitions)~* Straight leg raise (10 repetitions)~PNF technique steps:~* The subject is in supine position with his non-dominant leg strapped down the table while the dominant leg rests on the therapist right shoulder.~* The therapist stretches the hamstring muscle until the subject first reports a mild stretch sensation; held for 7 sec by passively flexing the hip with knee fully extended, allowing no hip rotation.~* Next, the subject isometrically contracts the hamstring muscle for 3 sec and then relax for 5 sec.~* This sequence is repeated 5 times at a 20 second interval.
Study NCT04766476 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-963272
Description: Specified dose on specified days
Study NCT04766476 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching BMS-963272
Description: Specified dose on specified days
Study NCT05850754 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vantage Hemp CBD
Description: Participants will consume 1 Vantage Hemp capsule, daily for 4 weeks.
Study NCT05850754 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Vantage Hemp Placebo Capsule
Description: Vantage Hemp Placebo Capsule Intervention
Study NCT04275141 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: oral glucose load
Description: oral glucose load (60g) followed by exercise at fixed wattage (60W) for 30 min
Study NCT04275141 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: exercise test
Description: oral glucose load (60g) followed by exercise at fixed wattage (60W) for 30 min
Study NCT06062745 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-fluciclovine
Description: 18F-fluciclovine is a radiotracer targeting amino-acid transporters.Radiotracers are compounds or drugs that are attached to small amounts of a radioactive substance to make images of processes that are happening in the body
Study NCT06062745 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PET/CT
Description: Positron emission tomography/computed tomography (PET/CT) uses small amounts of radioactive materials called radiotracers, a special camera and a computer to help evaluate organ and tissue functions.