AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04910048 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: POPOP (preoperative patient optimization program)
Description: A 2 month structured program focused on reduction of BMI, body weight, visceral fat, body fat and improvement of lean body mass and intracellular fluid.
Study NCT04910048 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SOC (standard of care)
Description: Referral to a dietician for two months of self-directed weight loss
Study NCT04425967 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: pre-operative radiotherapy
Description: pre-operative radiotherapy
Study NCT04425967 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: pre-operative radiotherapy
Description: pre-operative radiotherapy
Study NCT05179785 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous Theta Burst Stimulation (cTBS)
Description: cTBS is a brief stimulation of a part of the brain with a magnetic field that passes through the scalp and skull safely that can decrease the excitability of cortical neurons. It is FDA-approved as a treatment for psychological conditions including depression; however, this device is not approved for the treatment of adults with Bipolar Disorder I or for use in healthy adults. This research study is using the cTBS off label in all participants (those with and without Bipolar Disorder I) to examine research questions
Study NCT05179785 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Theta Burst Stimulation (iTBS)
Description: iTBS is a brief stimulation of a part of the brain with a magnetic field that passes through the scalp and skull safely to increase the excitability of cortical neurons. It is FDA-approved as a treatment for psychological conditions including depression; however, this device is not approved for the treatment of adults with Bipolar Disorder I or for use in healthy adults. This research study is using the cTBS off label in all participants (those with and without Bipolar Disorder I) to examine research questions.
Study NCT05100121 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Interactive app
Description: In the app, the patients will report frequency and distress on commons concerns regarding urine dysfunction, bowel dysfunction, emotional distress, sleep, pain, loss of appetite, hot flashes/sweating, edema, and sexual dysfunction. Free text comments will also be possible to make to cover the patients' other potential needs. Questions regarding symptoms of acute character that might need to be treated quickly like severe pain, blood in stool and urine, and involuntary weight loss will also be asked for to timely detect and treat signs of for example cancer relapse. Information about the concerns will be included in the app containing; a) general information of why they have the side effect and what it means b) evidence-based advice about self-management; c) when they should contact health care providers, and d) further information linked to reliable documents and web pages.
Study NCT05100121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive Care
Description: During the health dialogues with the nurse, the patient reported assessments will be used to discuss the individual's current situation and to plan eventual additional actions needed such as support from a physiotherapist, social worker, dietitian or if a visit to the physician if needed. This is documented in the patients health record.
Study NCT06112093 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation
Description: rTMS will be used to regulate the motor cortex to reduce headaches and post-concussion symptoms.
Study NCT06112093 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Repetitive Transcranial Magnetic Stimulation
Description: Sham rTMS will be delivered by a sham coil as a comparator to the (active) rTMS. Sham rTMS will not change the brain function of the control group.
Study NCT04909450 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CSB-001 Ophthalmic Solution 0.1%
Description: CSB-001: human recombinant dHGF (5-amino acid deleted hepatocyte growth factor)
Study NCT04909450 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Control
Description: Matching vehicle control without the drug substance
Study NCT05800210 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Miltenyi CliniMACS Prodigy ® system
Description: Subjects will receive an allogeneic stem cell transplant that has been depleted of ⍺/β CD3+ T-cells and CD19+ B-cells using the Miltenyi CliniMACS Prodigy® system.
Study NCT05005182 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT05005182 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow biopsy and aspirate
Study NCT05005182 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy and aspirate
Study NCT05005182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxyurea
Description: Given PO
Study NCT05005182 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Luspatercept
Description: Given SC
Study NCT05005182 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05249582 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Virtual reality wireless headset
Study NCT05249582 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Television Condition
Description: Individuals will mimic hand movements of a pre-recorded video of an individual playing the virtual reality climbing game
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized internal and external coping strategies
Description: A series of interactive, automated messages will recommend use of the internal coping strategies and external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized internal coping strategies
Description: A series of interactive, automated messages will recommend use of the internal coping strategies from the participant's personalized safety plan.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized external coping strategies
Description: A series of interactive, automated messages will recommend use of the external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General internal and external coping strategies
Description: A series of interactive, automated messages will recommend use of general (non-personalized) common internal and external coping strategies for suicidal thoughts.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General internal coping strategies
Description: A series of interactive, automated messages will recommend use of general (non-personalized) common internal coping strategies for suicidal thoughts.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General external coping strategies
Description: A series of interactive, automated messages will recommend use of general (non-personalized) external coping strategies (i.e., sources of social support/distraction) for suicidal thoughts.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General internal coping strategies, relaxation
Description: A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, relaxation-based) coping strategies for suicidal thoughts.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General internal coping strategies, distraction
Description: A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, distraction-based) coping strategies for suicidal thoughts.
Study NCT05791643 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General internal coping strategies, physical activity
Description: A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, physical activity-based) coping strategies for suicidal thoughts.
Study NCT05538325 — intervention group
Intervention type: DEVICE
Intervention: Bubble Inclinometer and Digital Pelvic Inclinometer
Description: They are valid and reliable devices to measure the range of motion of the lumbar spine
Study NCT03651349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HK-001
Description: HK-001 is synthesized by PharmaCore Biotech Co., Ltd. Synthetic (Z)-BP with high purity will be used in this proposed study.
Study NCT03651349 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo control
Description: In order to evaluate the safety and tolerability of HK-001 more accurately, a drug-free placebo control is planned to be utilized for the same administration route in this proposed trial. The placebo control that is identical in appearance, smell, weight, and excipients will be supplied by Everfront Biotech Inc.
Study NCT05164289 — intervention group
Intervention type: OTHER
Intervention: Control group
Description: Patients in the control group will have simple consultations on D15, D30, D45, D60 and D75
Study NCT05164289 — intervention group
Intervention type: OTHER
Intervention: EMDR group
Description: Patients in the EMDR group will have EMDR session on D15, D30, D45, D60 and D75
Study NCT06511258 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation
Description: The intervention includes 3 aspects (exercise, nutrition and breathing). Our intervention is a home-based multimodal prehabilitation program supported through an online platform.
Study NCT05058365 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: dots Curriculum
Description: dots is a mindfulness curriculum developed by Mindfulness in Schools Project (MiSP) for children aged 3-6 in pre-school settings. The program consists of 15-minute twice weekly lessons that span for fifteen weeks. dots has various suggestions for Have A Go after each session - both in the classroom and at home.
Study NCT05847192 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: [18F]-PI2620 PET scan
Description: The PET scan will measure the regional distribution of tau aggregation in AD patients with and without psychosis compared to Cognitively Unimpaired Healthy participants with the PET radiotracer \[18F\]-PI2620.
Study NCT04531410 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: linoleic acid supplementation
Description: Oils given daily at morning meal with extra enzymes
Study NCT04531410 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: oleic acid supplementation
Description: Oils given at morning meal with extra enzymes
Study NCT05759728 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNA3103: 5 x 10^7 cells
Description: CNA3103: 5 x 10\^7 cells - intravenous infusion
Study NCT05759728 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNA3103: 1.5 x 10^8 cells
Description: CNA3103: 1.5 x 10\^8 cells - intravenous infusion
Study NCT05759728 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNA3103: 4.5 x 10^8 cells
Description: CNA3103: 4.5 x 10\^8 cells - intravenous infusion
Study NCT05759728 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNA3103: 1.5 x 10^9 cells
Description: CNA3103: 1.5 x 10\^9 cells - intravenous infusion
Study NCT05759728 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CNA3103: 2.5 x 10^7 cells
Description: CNA3103: 2.5 x 10\^7 cells - intravenous infusion
Study NCT05520203 — intervention group
Intervention type: OTHER
Intervention: Care provided by the Nurse Practitioner
Description: Introduction of a Nurse Practitioner in the interdisciplinary care team
Study NCT04797585 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic supracervical hysterectomy
Description: Laparoscopic supracervical hysterectomy
Study NCT04797585 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vaginal hysterectomy
Description: Vaginal hysterectomy
Study NCT06537700 — intervention group
Intervention type: DRUG
Intervention: OnabotulinumtoxinA OBT-A
Description: Patients will be re-evaluated every 3 months, at each OBT-A cycle, during the whole year of treatment. Every evaluation patients will show their diary of headaches with monthly migraine and headache days and acute medications taken.
Study NCT05449418 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Full Intervention
Description: A small group of employees who work at facilities randomized to this arm will be invited to develop tailored COVID-19 vaccination promotion materials in teams with other long-term care staff sharing the same or similar language and/or cultural affinity. These employees will also help promote these materials to all of the employees who work at their facilities.
Study NCT05449418 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Employees who work at facilities randomized to this arm will see COVID-19 vaccine promotion materials from the Centers for Disease Control and Prevention \[CDC\] or other national organization.
Study NCT06569901 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hope Intervention
Description: Group meetings after hospital discharge reflecting on themes that may have an impact on hope.~The Hope Intervention consists of four group meetings and two individual conversations during a four week period.
Study NCT06154291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XON7
Description: The trial intervention (XON7) is a glyco-humanized polyclonal antibody drug which is formulated for intravenous (IV) administration
Study NCT06328686 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Arginine
Description: Given IV or PO
Study NCT06328686 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT06328686 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study NCT06328686 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT06328686 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spectroscopy
Description: Undergo spectroscopy
Study NCT06328686 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Whole-Brain Radiotherapy
Description: Undergo WBRT
Study NCT06446453 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Echography-guided Surfactant THERapy (ESTHER)
Description: Decision to administer surfactant therapy using a semi-quantitative lung ultrasound score.
Study NCT04382950 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Recombinant Bacterial ACE2 receptors -like enzyme of B38-CAP (rbACE2) plus Aerosolized 13 cis retinoic acid
Description: In this study, the experimental group will receive 0.4 mg/kg rbACE2 IV plus Aerosolized 13 cis retinoic acid in gradual in 2 divided doses increases froms 0.2 mg/kg/day to 4 mg/kg/day as inhaled 13 cis retinoic acid therapy for 14 days
Study NCT06301490 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial Release
Description: Myofascial release is a popular hands-on method manual therapy technique that uses carefully guided low load, long duration mechanical pressures to modify the myofascial complex (directly or indirectly), with the goal of restoring appropriate length, decreasing discomfort, and improving range of motion, muscle recovery, and physical performance in healthy persons.
Study NCT05682430 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Heart rate based HIIT
Description: Week1,90% HRmax long duration HIIT + 90% HRmax long duration HIIT. Week2,90% HRmax long duration HIIT + 90% long duration HRmax HIIT. Week3,90% HRmax long duration HIIT + 90% HRmax long duration HIIT. Week4,90% HRmax long duration HIIT + 90% HRmax long duration HIIT. Week5,90% HRmax short duration HIIT + 90～95% HRmax long duration HIIT. Week6,90% HRmax short duration HIIT + 90～95% HRmax long duration HIIT. Week7,90% HRmax short duration HIIT + 90～95% HRmax long duration HIIT. Week8,90% HRmax short duration HIIT + 90～95% HRmax long duration HIIT. Week9,90～95% HRmax short duration HIIT + 90～95% HRmax short duration HIIT. Week10,90～95% HRmax short duration HIIT + 90～95% HRmax short duration HIIT. Week11,90～95% HRmax short duration HIIT + 90～95% HRmax short duration HIIT. Week12,90～95% HRmax short duration HIIT + 90～95% HRmax short duration HIIT.
Study NCT05682430 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VIFT speed-based HIIT with mechanical work
Description: Week1,Wednesday 65% VIFT HIIT, saturday 65% VIFT HIIT. Week2,Wednesday 65% VIFT HIIT, saturday 65% VIFT HIIT. Week3,Wednesday 67.5% VIFT HIIT, saturday 67.5% VIFT HIIT. Week4,Wednesday 67.5% VIFT HIIT, saturday 67.5% VIFT HIIT. Week5,Wednesday 70% VIFT HIIT, saturday 90% VIFT HIIT. Week6,Wednesday 70% VIFT HIIT, saturday 90% VIFT HIIT. Week7,Wednesday 72.5% VIFT HIIT, saturday 92.5% VIFT HIIT. Week8,Wednesday 72.5% VIFT HIIT, saturday 92.5% VIFT HIIT. Week9,Wednesday 92.5% VIFT HIIT, saturday 100% VIFT HIIT. Week10,Wednesday 92.5% VIFT HIIT, saturday 100% VIFT HIIT. Week11,Wednesday 95% VIFT HIIT, saturday 105% VIFT HIIT. Week12,Wednesday 95% VIFT HIIT, saturday 105% VIFT HIIT.
Study NCT05846243 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VAC∆6 vaccine (10⁷ PFU)
Description: Live cell-based vaccine against smallpox and other orthopoxvirus infections (VAC∆6 vaccine) based on vaccinia virus (manufactured by FBRI SRC VB Vector, Rospotrebnadzor).~Batch: 08-10.19 (expiry date: 13.10.2021). Dosage: single intradermal dose of 10⁷ PFU/0.2 ml of vaccinia virus.
Study NCT05846243 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VAC∆6 vaccine (10⁶ PFU)
Description: Live cell-based vaccine against smallpox and other orthopoxvirus infections (VAC∆6 vaccine) based on vaccinia virus (manufactured by FBRI SRC VB Vector, Rospotrebnadzor).~Batch: 08-10.19 (expiry date: 13.10.2021). Dosage: two intradermal doses of 10⁶ PFU/0.2 ml of vaccinia virus (given 28 days apart).
Study NCT05846243 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Live Smallpox Vaccine
Description: Live smallpox vaccine (Smallpox vaccine) (manufactured by the Federal State Unitary Enterprise NPO Microgen of the Ministry of Health of Russia).~Batch No. Т30 (expiry date: March, 2021). Dosage: Single 1x10⁶ PFU dose administered by multiple-pricking technique on the 30th/60th day after full series of vaccination with VAC∆6.
Study NCT05846243 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Sodium chloride bufus, 0.9%)
Description: Sodium chloride bufus, a 0.9% solvent for the preparation of a dosage form for injections (manufactured by JSC Pharmaceutical manufacturing company Obnovlenie, Russia).~Batch: 391219 (expiry date: January, 2025).
Study NCT05195502 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biopsy
Description: Participants included in the study, will have additional biopsies performed during their colonoscopy
Study NCT04997473 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: W8L2G mobile health (mHealth) app
Description: Weight loss phone app based on addiction principles. This intervention has been validated in two prior studies. Participants will also interact with coaches throughout the intervention
Study NCT05142852 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extracorporeal shock wave therapy
Description: The participants in the experiment group received 5 consecutive sessions of ESWT for 5 minutes. Treatment parameters for the shock wave therapy group were set similar to a previous study (Devrimsel et al., 2013) 2000 shock waves with 1.6 bar intensity and 16 Hz frequency were applied for five sessions using the Swiss DolorClast Master (EMS, Nyon, Switzerland). All participants used 10-cm lateral epicondyle bandages in the treatment period, while none of them received analgesic or anti-inflammatory drugs and received exercise programs.
Study NCT05142852 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy
Description: The participants in the control group received 5 sessions of conventional physical therapy intervention for 5 minutes. The control group intervention consists of a 1-minute friction massage over the common extensor tendon of the elbow, followed by 3 minutes therapeutic ultrasound with a frequency of 1.5 Hz, and a 1-minute ice massage over the common extensor tendon of the elbow. All participants used 10-cm lateral epicondyle bandages in the treatment period, while none of them received analgesic or anti-inflammatory drugs and received exercise programs.
Study NCT04721535 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DWJ1248
Description: Orally, 1 tablet of DWJ1248 TID, up to 14 days
Study NCT04721535 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Orally, 1 tablet of placebo TID, up to 14 days
Study NCT05741359 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD19-targeted non-viral PD1 site-specific integrated CAR-T cell injection
Description: CD19-targeted non-viral PD1 site-specific integrated CAR-T cell injection
Study NCT06476756 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ACTIVE CYCLE OF BREATHING TECHNIQUE
Description: Group A: combine effects of ACBT and Buteyko techniques will be performed first 3days of cardiac rehab phase 1.