AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05767385 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neonatal Neurobehavioral Scale
Description: Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) evaluation: All neonates with CHD expected to undergo neonatal cardiac intervention or surgery have pre-operative NNNS assessment as PCH as standard of care. The NNNS takes approximately 30 minutes to complete. It is administered by a licensed physical, speech, or occupational therapist who has completed training and additional certification. The NNNS therapist will be blinded to the results of the fetal echocardiogram and MCA-PI.
Study NCT05110664 — intervention group
Intervention type: DRUG
Intervention: PYY (3-36) Peptide
Description: oral PYY3-36 solution
Study NCT05110664 — intervention group
Intervention type: DRUG
Intervention: Placibo
Description: oral placebo solution
Study NCT05733910 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: simultaneous integrated boost of carbon ions radiation therapy
Description: CIRT Treatment will be delivered in 16 fractions, 4 fractions per week. Treatment plans will be calculated with a Simultaneous Integrated Boost Approach (SIB).~The HR-CTV will receive a total dose of 65.6 GyRBE (4.1 GyRBE/fraction). The LR-CTV will simultaneously receive a total dose of 54.4 GyRBE (3.4 GyRBE/fraction) or 48 GyRBE (3 GyRBE/fraction) at discretion of Radiation Oncologist depending on the prognostic factors (54.4 GyRBE in case of macroscopical perineural invasion or positive margin along the nerve, 48.0 Gy(RBE) in case of elective perineural irradiation or microscopic focal intratumor perineural invasion).
Study NCT05107115 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rilzabrutinib
Description: Tablet, oral use
Study NCT05107115 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Tablet, oral use
Study NCT05257967 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Lumbar puncture and Phlebotomy
Description: Sampling of cerebral spinal fluid and plasma.
Study NCT05125445 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implants placed at bone crest
Description: Mid crestal incision will be performed and full-thickness envelope flap will be elevated to expose the alveolar ridge (no releasing incisions will be made).~Implant site will be prepared according to the manufacturer's instructions under sterile copious irrigation Implants will be placed at crestal level
Study NCT05125445 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implants placed 1mm Subcrestally
Description: Implants will be placed 1mm subcrestally
Study NCT06418945 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tinidazole oral microneedle patch
Description: Ultrasonic teeth cleaning: After gargling with compound chlorhexidine gargle or 3% hydrogen peroxide gargle for 1 minute, the teeth were cleaned by ultrasonic wave. After the teeth were cleaned, the wound was rinsed with 3% hydrogen peroxide to stop bleeding. Immediately after the ultrasonic cleaning, two pieces of tinidazole oral composite microneedle patch were applied to the upper and lower gums close to the inside of the first molar, especially on the tooth loss or damage, and the mouth was kept closed for 15 minutes. After the microneedle was fully degraded, the room could be left.
Study NCT06124469 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: US-guided fine needle aspiration (FNA)
Description: This study enrolled consecutive patients in follow-up for DTC history who underwent US-guided fine needle aspiration (FNA) of the LNs for suspicious metastatic cervical
Study NCT05927688 — intervention group
Intervention type: BEHAVIORAL
Intervention: Therapeutic management following access by the physician to his patient's ePROs
Description: Therapeutic management following access by the physician to his patient's ePROs
Study NCT04830280 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: posterior quadratus lumborum block
Description: administration local anesthetic solution between the middle layer of the thoracolumbar fascia and QL muscle at the posterior edge of the quadratus lumborum muscle
Study NCT04830280 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: posterior quadratus lumborum block
Description: administration local anesthetic solution between the middle layer of the thoracolumbar fascia and QL muscle at the posterior edge of the quadratus lumborum muscle
Study NCT05901220 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy lifestyle
Description: An educational programme to promote healthy lifestyle will be performed.
Study NCT05553717 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carvedilol
Description: Carvedilol 12.5mg\\12hr
Study NCT06443008 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Observation Group
Description: On the basis of myoelectric biofeedback treatment in the control group, the control group was trained alternately in each muscle group (triangle muscle, triceps brachii muscle group and forearm extensor muscle group). For example,After disinfection of the triangular, triceps and extensor muscles of the patient, the feedback electrode was attached to the area. The stimulation frequency was set at 50 Hz and the stimulation pulse width was set at 200 μs.During treatment, the patient is instructed to listen carefully to the device's password, drive the affected limb according to the specific password, and then perform tension and relaxation training.For each muscle group, the training time of each muscle group is about 0.5 h, 1 / d.In the later stage of treatment, the training intensity can be increased appropriately, so that the patient can carry out weight lifting during the feedback treatment, and listen to the password issued by the device to carry out muscle strength exercise.
Study NCT05201937 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-64281802
Description: JNJ-64281802 tablets will be administered orally as per the defined regimens.
Study NCT06269835 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: systemic therapy
Description: All participants were given routine rehabilitation treatment by professional rehabilitation therapists, including exercise therapy, guided education, psychological therapy, acupuncture and massage therapy, to promote the development of motor and cognitive function, as well as to improve intellectual development\[. Besides, swallowing function training was also provided, including direct training, indirect training, and compensatory training, as follows The mendelson maneuver: performed 5 days per week, twice per day, 5-10 minutes each time.~Cold stimulation of the pharynx: performed every day, twice per day, 3-5 minutes each time.~Passive head extension: to stretch the submental muscle for 2-3 seconds, with upward resistance applied to the lower cheek for no less than 5 times a day and no less than 5 minutes each time.~Direct feeding training: with powdered milk, once a day, 5 days a week.
Study NCT06269835 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: systemic therapy
Description: All participants were given routine rehabilitation treatment by professional rehabilitation therapists, including exercise therapy, guided education, psychological therapy, acupuncture and massage therapy, to promote the development of motor and cognitive function, as well as to improve intellectual development\[. Besides, swallowing function training was also provided, including direct training, indirect training, and compensatory training, as follows The mendelson maneuver: performed 5 days per week, twice per day, 5-10 minutes each time.~Cold stimulation of the pharynx: performed every day, twice per day, 3-5 minutes each time.~Passive head extension: to stretch the submental muscle for 2-3 seconds, with upward resistance applied to the lower cheek for no less than 5 times a day and no less than 5 minutes each time.~Direct feeding training: with powdered milk, once a day, 5 days a week.
Study NCT06269835 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-Esophageal Tube Feeding
Description: Within 4 hours of admission, the observation group were required to undergo nasogastric tube removal and initiated Intermittent Oro-Esophageal Tube Feeding for nutrition support. Before each feeding, the infant should rest for approximately 1 hour and undergo oral clean. During feeding, the infant should be held by the caregiver in a semi-reclined or upright position. Firstly, the tail of the tube was inserted via mouth into the upper part of the esophagus with a depth of 18-20cm, and the external part of the tube should be placed in water with the absence of bubbles indicating the successful tube placement. Subsequently, 1ml of water was slowly injected, followed by liquid food or water at a rate of approximately 50ml/min through a syringe connected to the feeding tube. After feeding, the tube should be slowly removed, and the feeding position should be maintained for 30-60 minutes to prevent reflux.
Study NCT06269835 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Persistent Nasogastric Tube Feeding
Description: The control group was given nutrition support with Persistent Nasogastric Tube Feeding, of which the tube passed through the nasal cavity into the stomach. After successful intubation, the tube was secured on the cheek. Liquid food was then syringe-fed into the stomach and the feeding was conducted every 2-3 hours, with each meal not exceeding 200 ml. The daily intake was generally consistent with that of the observation group. Besides, after successful intubation, the tube was secured on the infant's face and changed every one to two weeks.
Study NCT05806970 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Email Nudge
Description: An email to UCLA Health Cardiology clinic managers with a list of MRA-eligible HFrEF patients and a request to schedule or change cardiology appointments.
Study NCT06036095 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Inhalational maintenance of anesthesia group using sevoflurane
Study NCT06036095 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Intravenous maintenance of anesthesia group using propofol
Study NCT04597437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanamivir
Description: Intravenous zanamivir
Study NCT04597437 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: In the placebo group, participants will receive placebo normal saline solution intravenously every twelve hours for 5 days.
Study NCT04440488 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARALAST NP
Description: Partcipants will be randomized to receive ARALAST NP 60 or 120 mg/kg BW/week IV infusion for a total of 104 weeks.
Study NCT06014645 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: The study group will be given a core stabilization program in addition to education.
Study NCT06014645 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control group will receive post-operative cognitive training and will be encouraged to move.
Study NCT06530810 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10382+Flumatinib
Description: Drug:HS-10382+Flumatinib HS-10382 is administered orally BID Drug:Flumatinib Flumatinib 400mg once daily
Study NCT05925790 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: IL1RA Antibody Assay
Description: -The measurement of anti-interleukin-1 receptor antagonist (IL1RA) antibodies will be performed using the ELISA (Enzyme-Linked Immunosorbent Assay) method,as previously described \[Thurner, L., et al., IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination. N Engl J Med, 2022. 387(16): p. 1524-1527\].
Study NCT05672875 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Anthrax LF Dx System
Description: Lateral flow immunoassay for the detection of the LF biomarker in whole blood samples.
Study NCT06132802 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients who received treatment involving ARS and arthrocentesis only
Description: A 5mm acrylic anterior repositioning splint (ARS) with maxillary coverage was crafted from alginate impressions. After arthrocentesis, the ARS was worn incrementally over six months, starting at two hours and reaching 14 hours daily. In the second week, wear time was continuous, increasing to 24 hours daily (excluding meals) until the sixth month. The ramp was removed in the seventh week. Follow-ups involved grinding the splint by 1mm every four weeks. Arthrocentesis included anesthesia, betadine prep, and using two 18-gauge needles to inject Ringer's lactate solution (100-200 cc) for joint lavage, freeing the disc by moving the lower jaw in various orientations.
Study NCT06132802 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
Description: A 5mm acrylic anterior repositioning splint (ARS) was crafted from alginate impressions, secured with Adam's clasps on upper first molars. After arthrocentesis, patients wore the splint incrementally over six months, starting at two hours and reaching 24 hours daily (excluding meals). The ramp was removed in the seventh week, and follow-ups included grinding the splint by 1mm every four weeks until it reached 3mm, guided by articulating paper.~Arthrocentesis involved administering anesthesia, prepping the area with betadine, and using two 18-gauge needles to inject 2-3 ml of Ringer's lactate solution for joint lavage. The lower jaw was moved to free the disc and release fibrous tissue. I-PRF preparation included centrifuging collected blood for 3 minutes at 700 rpm, and the resulting I-PRF was injected into the superior joint space of the lavaged joints.
Study NCT05676554 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: An Enhanced Psychological Mindset Session for Adolescents
Description: It is a ten-minute psychoeducation video (animation) delivered on the internet, followed by five minutes of stories from fictional students about how they used the concepts. Participants then complete three multiple choice questions aimed to assess their understanding and ability to apply concepts from the video, followed by 'letter of advice' task where participants have to give advice to a fictional younger student based on the information presented in the animation and videos.~The intervention itself was developed by Perkins et al (2021) based on promoting a growth mindset. It was deemed to be a feasible and acceptable tool to promote mental health (Perkins et al., 2021) in their feasibility trial.
Study NCT05338632 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Narcan 40 MG/ML Nasal Spray
Description: naloxone 4mg/0.1 mL intranasal spray, up to 4 doses intranasally, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously
Study NCT05338632 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone Hydrochloride
Description: naloxone 0.4mg/ml, up to 4 doses 2mg intramuscularly, followed by 1ml 0.4 mg/ml naloxone hydrochloride intravenously
Study NCT05925790 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: suPAR Testing
Description: -The quantitative determination of soluble urokinase plasminogen activator receptor (suPAR) levels in blood will be conducted using the commercially available CHORUS suPAR Extended kit (cod. 81414, DIESSE Diagnostica Senese S.p.A., Siena, Italy), based on the principle of the sandwich ELISA method.
Study NCT05694468 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Psychomotor Relaxation
Description: Psychomotor relaxation sessions.
Study NCT06514859 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparoscopic repair of inguinal hernia
Description: Laparoscopic repair of inguinal hernia
Study NCT06514859 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open repair of inguinal hernia
Description: Repair of inguinal hernia by open technique-mesh hernioplasty -
Study NCT05162456 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: assessment of the anti-SARS-CoV-2 IgG antibody titer in 3-dose schedule
Description: evaluation of anti-SARS-CoV-2 IgG antibodies in patients after 2-dose vaccination schedule willing to receive a 3rd dose of vaccine
Study NCT05162456 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: assessment of the anti-SARS-CoV-2 IgG antibody titer in 2-dose schedule
Description: evaluation of anti-SARS-CoV-2 IgG antibodies in patients after 2-dose vaccination schedule unwilling to receive a 3rd dose of vaccine
Study NCT05572931 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fu's Subcutaneous Needling(FSN)
Description: Insertion points are both sides of 1) inferior edge of the scapula; 2)the midpoint of inferior edge of the posterior superior iliac spine and the ischial tuberosity.~FSN (Trocar Acupuncture Needle, Nanjing FSN Medical Co. , Ltd, China.) ) is a solid needle with plastic cannula tube on the outside. Add on swaying movement (SM) and reperfusion approach (RA) after the needle inserting into the subcutaneous layer. The SM is a horizontal fan sway movement with the base of the needle for the fulcrum, The SM speed is 200 times in 2 minutes. Apply RA when performing SM. RA movement is hip extension in prone position with resistance by physician's hand for 10 seconds. And then rest for 10 seconds. Repeat 3 cycles. The same RA is performed over the other three insertion point.
Study NCT05572931 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: fine acupuncture needle
Description: (36G, 0.5 inch, Wujiang city cloud \& dragon medical device Co.,Ltd.) Only inserted to skin, not into the subcutaneous layer. No SM and RA.
Study NCT04885608 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PReGe
Description: There will be two weekly sessions of 45 minutes, outdoors in outdoor fitness parks. The components of balance, gait, resistance, strength and elasticity will be worked on and breathing exercises will be performed. The sessions will be guided and dosed by physiotherapists, considering the level of perception of effort. Indications will be given to carry out other sessions of 60 to 120 minutes of therapeutic walking (minimum speed of 4 km/hour) during the week, to complete the 150-300 minutes per week of physical activity recommended by the WHO.
Study NCT06467721 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Self-adhesive silicone gel waterproof dressing
Description: Self-adhesive silicone gel waterproof dressing is used after artificial joint replacement surgery.
Study NCT06467721 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sterile gauze dressing
Description: Sterile gauze dressing is used after artificial joint replacement surgery.
Study NCT06519630 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rehabotics Physiotherapy
Description: The intervention will be consisted of sessions for participants in the intervention group which includes a repetition of each of the four Sollerman AR Games named, Wallet, Key, Jar, Screwdriver and one repetition of Balloon Pop. Participants will interact with the AR Box and Block Test (BBT) and the serious games under controlled conditions. A clinician will be present throughout the whole session providing help if participants encounter any difficulties. Following the games, the clinician will initiate a stretching program using the Active Exoskeletal Aid, performing 3 sets of 10 repetitions on the finger flexors of the patient's hand. Each rehabilitation session will last 30 minutes and will be conducted three times a week. Similarly, the traditional physiotherapy training program will be prescribed for the control group and will be consisted of sessions lasting 30 minutes per day, three days per week. Both programs duration will be five weeks.
Study NCT06519630 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Physiotherapy
Description: Similarly, the hand functional training program prescribed for the control group consisted of sessions lasting 30 minutes per day, three days per week. Both programs lasted for five weeks and were designed by two clinical experts.
Study NCT05267717 — intervention group
Intervention type: OTHER
Intervention: Non-interventional study, all patients being tested with AG Pregnolia System to assess the values of the Cervical Stiffness
Description: Non-interventional study,
Study NCT05413109 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Coronary CT angiography
Description: A coronary CT angiography will be used to study the relationship between the PA and the LMCA and 4 radiological patterns will be considered:~1. Normal: minimum distance between the two vessels> 1 mm;~2. Proximity: distance between the two vessels ≤1 mm without displacement or stenosis of the LMCA;~3. Dislocation: dislocation of the LMCA by the main branch of the PA with a take-off angle \<60 ° (the take-off angle is defined by the angle formed by the perpendicular to the aortic valve ring and the longitudinal axis of the LMCA);~4. Compression: stenosis of the LMCA ≥50% due to extrinsic compression by the PA.
Study NCT05023083 — intervention group
Intervention type: OTHER
Intervention: Functional Status Questionnaire Urdu version
Description: The FSQ instrument translated into Urdu consists of only 34 items, main sections addressed physical function in the activities of daily living, psychological function, role function, social function and variety of performance measures.(8) Scores range from a 0 - 4, 1 - 4, and 1 - 6 scale per question depending on section. It increases reliability and patients ease and comfort. Total score range from 0 to 100 higher score represents the more severe condition.
Study NCT05023083 — intervention group
Intervention type: OTHER
Intervention: Original Functional Status Questionnaire
Description: FSQ was developed to allow the comprehensive and efficient assessment of physical, psychosocial, social, and role functioning in ambulatory patients. It is a self-administered survey that takes approximately 15 min to complete. The results can be scored to produce a one-page report for clinicians to use in their practices. The responses to items within a scale are averaged and transformed to a scale with a potential range of 0 to 100.Higher score represents the more severe condition.
Study NCT05705843 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraosseous Vancomycin Injection
Description: • IO vancomycin is administered via an intraosseous cannulation device (Arrow EZ-IO; Teleflex, Morrisville, NC) in the OR after sterile prep and draping has occurred prior to skin incision (500mg in 150mL NS).