AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06686316 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Device: Hypoxic Gas Mixture
Description: The EG (Experimental Group) will undergo a 6-week intervention protocol of IHHE (Intermittent Hypoxia-Hyperoxia Exposure) using the MITOVIT® Hypoxic Training System (COMMIT GmbH, Salzgitter, Germany). They will breathe air with an oxygen concentration (FiO2) ranging from 10-14% for 5 minutes, followed by 3 minutes of rest in hyperoxia (FiO2 30-40%), for a total of 6 cycles. During the hypoxic phase, oxygen saturation will be maintained between 85-92%, while during the hyperoxic phase, it will be kept above 95%. This process is regulated by the device's AI. Participants will be asked to sit and breath normally in each exposure. An attendance checklist will be used to monitor compliance with the intervention
Study NCT06686316 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Hypoxic-Hyperoxic exposure
Description: The Sham Group (SG) will follow a single session protocol of 5 cycles of 6 minutes per session with an FiO2 of 21% using the MITOVIT® Hypoxic Training System (COMMIT GmbH, Salzgitter, Germany). Participants will be asked to sit and breath normally in each exposure. An attendance checklist will be used to monitor compliance with the placebo intervention.
Study NCT06692036 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adaptive Blood Purification (ABP)
Description: Patients in the intervention group, based on standard treatment, received two 6-hour adaptive blood purification (ABP) treatments within 24 hours after enrollment, that is, patients did not indicate renal replacement therapy (RRT), only coupled plasma filtration and adsorption (CPFA) therapy is used to adsorb inflammatory factors; for patients with acute kidney injury (AKI) and meeting RRT indications, CPFA+RRT (plasma filtration adsorption dialysis, PFAD) treatment is used.
Study NCT06707129 — intervention group
Intervention type: OTHER
Intervention: life-style
Description: The patients were given health education and lifestyle intervention guidance, followed by lifestyle adjustment for at least 1 year and no more than 3 years, and a second liver biopsy was performed to evaluate liver histological changes.
Study NCT06710912 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group acceptance and commitment therapy (ACT)
Description: The ACT intervention module utilized in this study was adapted from Hayes foundational work on ACT and Harris. A summary of the general contents and exercises in each week was in accordance with the 6 core processes of Acceptance and Commitment Therapy based on Hayes. It was conducted in the Malay language. The same workbook with guided exercise and homework were used by all the therapists to assure standardization of the intervention to ensure that each group received similar contents in each session.
Study NCT06710912 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: Standard care and follow-up for major depressive disorder
Study NCT06709560 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Moderate Intensity Continuous Exercise
Description: Participants perform a continuous cycling exercise session on a reclined ergometer at moderate intensity (50% HRR)
Study NCT06709560 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Vigorous Intensity Continuous Exercise
Description: Participants perform a continuous cycling exercise session on a reclined ergometer, at a vigorous intensity (80% HRR).
Study NCT06709560 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moderate Intensity Continuous Exercise Matched for Blood Pressure
Description: Participants perform a cycling session where exercise intensity is adjusted to match the systolic blood pressure levels attained during the first visit at moderate intensity (50% HRR).
Study NCT06709560 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vigorous Intensity Continuous Exercise Matched for Blood Pressure
Description: Participants perform a different cycling session where exercise intensity is adjusted to match the systolic blood pressure levels attained during the first visit at vigorous intensity (80% HRR).
Study NCT06710431 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: AFA-281
Description: AFA-281
Study NCT06710431 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: AFA-281
Description: AFA-281
Study NCT06708741 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: High dose oral vitamin D supplementation (50,000 IU/once per month)
Study NCT06709885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chidamide + Tislelizumab + chemotherapy (CapeOX )
Description: Chidamide + Tislelizumab + chemotherapy (CapeOX regimen): 4 cycles of combination therapy (q3w; Day1 Oxaliplatin, 130mg/m2, iv.gtt; tislelizumab, 200mg/m2 iv.gtt; Day1,4,8,11Chidamide 20 mg BIW,PO; Day1-Day14, capecitabine 850-1000mg/m2, BID, PO) ；After completing the surgery, Post-operation 4 cycles of Capeox
Study NCT06709885 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CapeOX
Description: 4 cycles (q3w; Day1 Oxaliplatin, 130mg/m2, iv.gtt; Day1-Day14, capecitabine, 850-1000mg/m2, BID, PO. ） Post-operation 4 cycles of Capeox
Study NCT06707948 — intervention group
Intervention type: PROCEDURE
Intervention: Arthroscopic meniscus surgery
Description: Comparison of the incidence of osteoarthritis with conservative treatment as well as arthroscopic partial resection as well as arthroscopic repair surgery for a condition known as posterior meniscus root injury.
Study NCT05385523 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rhomboid Intercostal and Sub-Serratus block technique (RISS)
Description: The patient will be placed in lateral position. A linear ultrasound transducer of frequency 6-12 MHz will be placed medial to the lower border of the scapula in a sagittal plane. A 38-mm 22-gauge will be inserted under real-time in-plane from craniocaudal between the rhomboid major and intercostal muscles. After negative aspiration, single injection of 10 ml of the local anesthetic mixture will be administered at the T6 7 level. The spread of local anesthetic solution under the rhomboid muscle will be visualized by ultrasonography. Then the ultrasound probe will be moved caudally and laterally to identify the tissue plane between the serratus anterior and external intercostal muscle for the sub-serratus block at T 8-9 level. The needle will be advanced from its previous position and a further of 10 ml of the local anesthetic mixture will be injected.
Study NCT01374945 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Clearpath Lower GI
Description: Clearpath device for cleaning of colon by irrigation and evacuation
Study NCT05385523 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General Anaesthesia
Description: Fentanyl (1 μg/kg), propofol (2-3mg/kg) and atracurium (0.3-0.5 mg/kg) will be injected intravenously 3-5 minutes after oxygenation. A single-lumen endotracheal tube will be used to complete ventilation. The ventilator ventilation mode is volume control mode, and the patient's end-expiratory carbon dioxide level is maintained at 35-40 mmHg throughout the anesthesia process. During the anesthesia maintenance phase, 2% sevoflurane mixed with 60% oxygen.~After general anaesthesia induction, all patients will receive RISS block with different local anesthetic drug mixture according to randomization.
Study NCT05958056 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance exercise
Description: The training session included leg curl and leg extension exercises with 4 sets each. Participants started with leg extension exercise for 4 sets with a 30-second rest periods between the sets. Then, participants took a rest for 60 seconds. Afterward, participants performed leg curl exercise for 4 sets with a 30-second rest periods between the sets. Exercises in each set were performed continuously (uninterrupted) with a speed of 2 seconds for each repetition and a medium exercise performance speed.
Study NCT05958056 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance exercise
Description: The training session included leg curl and leg extension exercises with 4 sets each. Participants started with leg extension exercise for 4 sets with a 30-second rest periods between the sets. Then, participants took a rest for 60 seconds. Afterward, participants performed leg curl exercise for 4 sets with a 30-second rest periods between the sets. Exercises in each set were performed continuously (uninterrupted) with a speed of 2 seconds for each repetition and a medium exercise performance speed.
Study NCT06708715 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PEACE Patch
Description: A topical patch that incorporates a sensory pattern of vibrotactile haptic technology.
Study NCT06708715 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Topical Sham Patch
Description: Sham Patch that does not include vibrotactile haptic technology
Study NCT06707779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF with electrical stimulation
Description: Group A receive PNF including combination of isotonic and rhythmic stabilization on trunk with electrical stimulation Participants perform three sets10 repetitions at maximal resistance The resting interval of 30 seconds and 60 seconds will be provided after the completion of 10 repetitions for each pattern and between sets respectively.~In total all PNF exercise will be held for 30 to 45 minutes. 'BURST' TENS (acupuncture-like TENS), characterized by discontinuous stimulation at low frequencies (1-4 Hz), with wave durations of 100-400 ms and high intensities, inducing weak muscle twitches for 10 minutes.
Study NCT06707779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF without electrical stimulation
Description: Group B receive PNF including combination of isotonic and rhythmic stabilization on trunk without electrical stimulation. Participants perform three sets of 10 repetitions at maximal resistance will be provided by the same physiotherapist.~The resting interval of 30 seconds and 60 seconds will be provided after the completion of 10 repetitions for each pattern and between sets respectively.~In total all PNF exercise will be held for 30 to 45 minutes.
Study NCT06709092 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lupatadine fumarate (Luso®, Yangzijiang Pharmaceuticals)
Description: For patients with AR, patients were given lupatadine fumarate (Luso®, Yangzijiang Pharmaceuticals) 1 tablet once daily at bedtime for 14 days.
Study NCT06707467 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: occlusal splint
Description: nineteen patients diagnosed with internal temporomandibular derangement will receive occlusal splint therapy, a treatment method with proven effectiveness.
Study NCT06707467 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: occlusal splints combined with rocabado exercise
Description: Nineteen patients diagnosed with internal temporomandibular derangement will be provided with Rocabado exercises in addition to the proven-effective treatment method of occlusal splint therapy. This approach aims to evaluate whether Rocabado exercises have a positive effect on the treatment process.
Study NCT06707467 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: occlusal splint combined with posture exercise
Description: Nineteen patients diagnosed with internal temporomandibular derangement will be provided with posture exercises in addition to the proven-effective treatment method of occlusal splint therapy. This approach aims to evaluate whether posture exercises have a positive effect on the treatment process.
Study NCT06708975 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Insulin therapy phonophoresis
Description: Insulin therapy phonophoresis is the use of ultrasound to deliver drugs through patients skin, Insulin therapy will be used to determine its effect on wound healing in patients with chronic diabetes mellites because in addition to its systemic impact, numerous reports suggest that applying insulin topically causes localized effects. Many trials and case reports have been released reporting positive effects of topical insulin for many diseases such as dermatological compromises, ophthalmological diseases and others
Study NCT06708975 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hyperpolarized light therapy and Standard wound cleaning and dressing.
Description: Hyperpolarized light therapy safely accelerates wound healing by stimulating blood circulation, reducing inflammation and relieving muscle spasms.
Study NCT06708975 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Hyperpolarized light therapy and Standard wound cleaning and dressing.
Description: Hyperpolarized light therapy safely accelerates wound healing by stimulating blood circulation, reducing inflammation and relieving muscle spasms.
Study NCT06710951 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Change of normal concentration of povidone-iodine 5% to 1%
Description: Normal concentration of povidone-iodine during anti-VEGF intravitreal injection was 5%. That concentration was utilized in the control group, and 1% in the experimental group.
Study NCT06710951 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Change of normal concentration of povidone-iodine 5% to 1%
Description: Normal concentration of povidone-iodine during anti-VEGF intravitreal injection was 5%. That concentration was utilized in the control group, and 1% in the experimental group.
Study NCT06706596 — intervention group
Intervention type: OTHER
Intervention: Screening for TB symptoms
Description: Individuals will be screened for cough, blood in sputum, fever, weight loss, night sweats and chills lasting for >2 weeks
Study NCT06706596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Chest X-ray
Description: Chest X-ray will be performed to diagnose or exclude TB
Study NCT06710301 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preliminary assessment
Description: Evaluation of the cognitive level through the Raven test and of spatial navigation skills through the Corsi test and the maze sub-test of the WISC-III.
Study NCT06710301 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Navigation task with EEG recording
Description: Administration of the navigation task in an immersive virtual reality environment and EEG signal recording. The participant will wear virtual reality viewers and EEG cap. The task consists in moving and orienting themselves inside a five-way maze in order to reach a treasure. The participant will be asked to carry out 30 trials lasting a maximum of 120s each.
Study NCT06710496 — intervention group
Intervention type: OTHER
Intervention: analysis of medical records
Description: analysis of medical records of the patients
Study NCT06707259 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-CD19 IL10 CAR-NK
Description: Lentiviral vector-transducted cord blood-derived NK cells to express anti-CD19-IL10 CAR
Study NCT06737601 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: shock waves
Description: three sessions, weekly frequency
Study NCT06742554 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Buprenorphine transdermal patch
Description: Buprenorphine Transdermal Patch (10 mg): Applied once before surgery for continuous pain control.~Interscalene Brachial Plexus Block: Administered intraoperatively using 25 mL of 0.5% bupivacaine.
Study NCT06742554 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: Tramadol: Administered orally or intravenously at a standard dose of 100 mg every 8 hours, based on patient-reported pain levels.~Interscalene Brachial Plexus Block: Administered intraoperatively using 25 mL of 0.5% bupivacaine.
Study NCT06738407 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxycycline hyclate delayed released 200 mg
Description: 200 mg of doxycycline taken by mouth as soon as possible and within 72 hours after any condomless oral, vaginal/front hole, and/or anal sex.
Study NCT06738407 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxycycline hyclate delayed released 200 mg weekly
Description: 200 mg of doxycycline taken by mouth weekly regardless of sexual activity
Study NCT06744179 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: echocardiography, chest x-ray, full blood count , SGPT, lipid profile, HbA1C, AQ20 questionnaire, mmRC dyspnoea scale, Duke activity status index, COPD assessment test, Age and stage questionnaire
Description: Participants from both exposed and non-exposed groups will be assessed using different standardized questionnaire and a number of investigations to identify any cardiac and pulmonary complications over time. Individuals will be matched for age and sex to ensure comparability. This study aims to evaluate these complications and analyze any significant differences between the groups over the defined follow-up period.
Study NCT06745180 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Short Message System (SMS)
Description: The Short Message System (SMS) intervention focuses on personalized, adaptive SMS messages that help the participant maintain physical activity behaviors.
Study NCT06745180 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Coach
Description: The peer coach will deliver an intervention that will help participants maintain physical activity.
Study NCT06745180 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Usual Care
Description: Participants will be given written materials providing advice on maintaining their physical activity.
Study NCT06745180 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Coach and SMS
Description: The Short Message System (SMS) intervention focuses on personalized, adaptive SMS messages that help the participant maintain physical activity behaviors. The peer coach will deliver an intervention that will help participants maintain physical activity.
Study NCT06744933 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Self-administered auricular acupressure integrated with a smartphone application
Description: 6 to 8 Vaccariae Semen ear patches will be affixed on one ear of the patient. The patient will be required to press on the ear patches 3 times a day, and 30 minutes before a meal. Every 3 to 4 days, the patient will visit the clinic to change a new set of ear patches on the same auricular acupoints of the opposite ear alternately. The whole course of intervention will be 8 weeks. The smartphone app will send scheduled pop-up notifications to remind patients to press on the ear patches. The patient will be required to enter the number of times pressing and of defaecation every day on the smartphone application. The smartphone application will send more notifications to the patient if he/ she has a low compliance. When the participants record the number of times pressing on the auricular acupoints, positive reinforcement messages will pop-up, such as Excellent job! for those with good compliance while You are almost there! Keep going! for those with poor compliance.
Study NCT06313593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCB160058
Description: Oral; Tablet
Study NCT06528873 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Concurrent optical and magnetic stimulation (COMS) treatment
Description: COMS treatment will be performed 2-3 times per week for at least 8 weeks, unless the wound heals sooner, with a minimum of 16 applications. Missed sessions can be made up in the 4-week follow-up period. Treatment will occur during standard care procedures, including dressing changes and debridement, and will follow these steps:~Remove old dressing Apply analgesic if necessary Perform debridement if necessary Cleanse the wound Apply COMS One device Apply new dressing Apply compression therapy as per study procedures (section 6.1)~If the patient is at home, a caregiver will perform this procedure. Study staff, including the PI, nurses, and caregivers, will receive training and a step-by-step document on using the COMS One device.
Study NCT06067204 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automatic ventilation
Description: The FDA-approved device used is Meditech MICROVENT RESUSCITATOR, which is connected to the endotracheal tube, supraglottic airway or tracheostomy tube. It is powered by the airflow from the oxygen tank and provides ventilation in fixed interval. It has a pressure valve which will release the pressure once the airway pressure exceeds its threshold. In the current study, the threshold is set at 60 mmH2O. The tidal volume is set at 500-600 ml.
Study NCT05385523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexamedatomidine
Description: Patients will receive general anaesthesia and RISS block with 20 ml of 0.25% bupivacaine + 1 Mcg/kg dexamedatomidine in 2 mL.
Study NCT05385523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexamethasone
Description: Patients will receive general anaesthesia and RISS block with 20 ml of 0.25% bupivacaine + 8mg dexamethasone in 2 mL.
Study NCT05385523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: saline
Description: Patients will receive general anaesthesia and RISS block with 20 ml of 0.25% bupivacaine+ 2 mL normal saline.
Study NCT06413875 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: education
Description: Education Specific to Menopause Symptoms
Study NCT06569511 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: N-terminal pro-B-type natriuretic peptide (NT-proBNP)
Description: In patients diagnosed with Acute coronary syndrome, blood samples for serum NT-proBNP value were taken during transfer to the coronary intensive care unit
Study NCT06569511 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: high sensitive cardiac troponin T (hs-cTnT)
Description: In patients diagnosed with Acute coronary syndrome, serum high-sensitive cardiac troponin T (hs-cTnT) levels were measured on admission to the Emergency Department.
Study NCT05301192 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angiotensin-(1-7)
Description: This is a biologically active endogenous angiotensin peptide that may play an important role in regulation of blood pressure.
Study NCT05301192 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline will be used as the placebo comparator.