AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06302140 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nanatinostat mesylate tablets in combination with Valganciclovir
Description: Treatment B: a single, oral dose of nanatinostat mesylate tablets (20 mg) in combination with valganciclovir (900 mg) under fed conditions.
Study NCT06302140 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single-agent Nanatinostat (free base) tablets
Description: 40 mg once daily under fed conditions until disease progression or unacceptable toxicity, whichever occurs first.
Study NCT05162261 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tixel C
Description: Tixel C by Novoxel®, Israel is a thermomechanical system developed for fractional treatment. The system is designed for the treatment of soft tissue by direct conduction of heat, enabling tissue coagulation combined with micro ablation with low thermal damage to the surrounding tissue.
Study NCT05162261 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LipiFlow
Description: Thermal pulsation (LipiFlow) consists of the localized application of heat and therapeutic pressure on the four eyelids (upper and lower) with the aim of improving drainage of the Meibomian glands.
Study NCT05554029 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Coronaphobia
Description: Coronophobia will be assessed with COVID-19-phobia scale.
Study NCT05649670 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile Stroke Unit deployment
Description: Deployment of an MSU + conventional ambulance, allowing prehospital CT-scan imaging with intracranial CT angiography. This will allow prehospital intravenous thrombolysis and optimal triage (i.e. accurate identification of patients with large vessel occlusion, who are eligible for mechanical thrombectomy).
Study NCT05982106 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ05105 Tablets
Description: TQ05105 tablet is a novel JAK2 inhibitor.
Study NCT06265090 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapeutic exercises
Description: Protocol of hemibridge with ball and balloon exercise Participants were given exercise called as hemibridge with ball and balloon exercise for 3 sessions over 3 days/week.
Study NCT06265090 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: therapeutic exercises
Description: Protocol of hemibridge with ball and balloon exercise Participants were given exercise called as hemibridge with ball and balloon exercise for 3 sessions over 3 days/week.
Study NCT06265090 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercises
Description: The second group received hemibridge with ball and balloon exercise in combination to core stability exercises.~Protocol of hemibridge with ball and balloon exercise The hemibridge with ball as well as balloon exercise was provided to the participants over the course of three sessions per week.~Instructions~1. supine-lying position, feet up against a wall, and bend your knees as well as hips to a 90° angle.~2. Insert a ball measuring between four and six inches in diameter in the space between your knees.~3. Put your left hand upon a balloon and your right arm above your head.~4. Tilt your pelvis to make sure your tailbone is just slightly elevated off the ground while you inhale with your nose and exhale using your mouth. Keep your low back as flat as possible on the mat. Dig your heels into the wall instead of pushing your feet flat.~5. drop your left knee till it is below the level of your right, without moving your feet. the activation of your left inner thigh muscle.
Study NCT06265090 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercises
Description: The second group received hemibridge with ball and balloon exercise in combination to core stability exercises.~Protocol of hemibridge with ball and balloon exercise The hemibridge with ball as well as balloon exercise was provided to the participants over the course of three sessions per week.~Instructions~1. supine-lying position, feet up against a wall, and bend your knees as well as hips to a 90° angle.~2. Insert a ball measuring between four and six inches in diameter in the space between your knees.~3. Put your left hand upon a balloon and your right arm above your head.~4. Tilt your pelvis to make sure your tailbone is just slightly elevated off the ground while you inhale with your nose and exhale using your mouth. Keep your low back as flat as possible on the mat. Dig your heels into the wall instead of pushing your feet flat.~5. drop your left knee till it is below the level of your right, without moving your feet. the activation of your left inner thigh muscle.
Study NCT05436561 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MBF-RIC
Description: Reduced intensity conditioning regimen with fludarabine, busulfan and melphalan
Study NCT05594147 — intervention group
Intervention type: DRUG
Intervention: Non-TKIs
Description: Retrospective cohort analysis, using IBM MarketScan and Optum Clinformatics database in the US.
Study NCT05594147 — intervention group
Intervention type: DRUG
Intervention: Other TKIs
Description: Retrospective cohort analysis, using IBM MarketScan and Optum Clinformatics database in the US.
Study NCT05594147 — intervention group
Intervention type: DRUG
Intervention: Regorafenib (Stivarga, BAY73- 4506)
Description: Retrospective cohort analysis, using IBM MarketScan and Optum Clinformatics database in the US.
Study NCT05594147 — intervention group
Intervention type: DRUG
Intervention: Sorafenib (Nexavar, BAY43-9006)
Description: Retrospective cohort analysis, using IBM MarketScan and Optum Clinformatics database in the US.
Study NCT05588843 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR443122
Description: oral capsule
Study NCT04967807 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Cardiac PET/MRI
Description: An imaging technique that combines the strengths of both MRI and PET into one comprehensive study. This technique allows for detailed myocardial tissue characterization with MRI (including assessment of myocardial edema and fibrosis) and metabolic changes (including myocardial inflammation).
Study NCT04967807 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Blood Biomarkers
Description: Markers of cardiac damage, inflammation, circulating microRNA profiles, and COVID antibody levels will be evaluated in patients after COVID-19 vaccination.
Study NCT04283812 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DBS Electrode Implantation using D1 Sterotactic System
Description: Treatment intervention will consist of subjects undergoing Mayo Clinic standard deep brain stimulation surgery specific to their diagnosed neurological disorder consisting of implantation of stimulating electrodes using the D1 stereotactic system.
Study NCT04917848 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tele-Geriatric Oncology program
Description: Participants will be scheduled to meet with a Geriatric Nurse Practitioner (GNP) or Geriatric Registered Nurse (GRN) via the program's telemedicine platform. The telemedicine encounters with the GNP/GRN may occur every 2 weeks over 3 months, for a total of 6 visits. Visits 1 and 6 are mandatory, and visits 2-5 are on an as needed basis.
Study NCT05588843 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral capsule
Study NCT05958823 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Serratus anterior plane block
Description: Serratus anterior plane block
Study NCT05958823 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PECS I-II
Description: PECS I-II
Study NCT05611931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Dose: 60 mg (3 tablets); Dosage form: film-coated, immediate-release tablet of 20 mg each; Route of administration: oral
Study NCT05293860 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Connective tissue manipulation
Description: Connective tissue manipulation will be applied to participants' back for 5-20 minutes, 3 times a week for 4 weeks in this group.
Study NCT05293860 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Superficial massage with the head of the therapeutic ultrasound device
Description: Superficial massage with the head of the therapeutic ultrasound device will be applied to participants' back for 15 minutes, 3 times a week for 4 weeks in this group.
Study NCT06014177 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STIckER
Description: STIckER is an interactive and personalized intervention based on the principles of SDM that has been designed with input from the AYA ED patients and providers. STIckER guides AYA patients through a series of steps, beginning with scanning your STIckER. Participants complete risk assessments, SDM modules, and conclude with an anonymous final digital infographic that informs an SDM conversation with the medical provider. This decision aid seamlessly integrates into the ED workflow, recommending appropriate STI testing for high-risk individuals and using SDM concepts for those at intermediate risk.
Study NCT06014177 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: After enrollment but before the start of their clinical visit, AYA participants assigned to a provider in the control arm will scan a QR code. They will receive a prompt stating, If you would like to be tested for a sexually transmitted infection today, please tell your medical doctor.
Study NCT04591106 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance imaging (MRI)
Description: Magnetic resonance imaging (MRI) is a non-invasive imaging technique that uses a magnetic field and radio waves to create detailed images of the organs and tissues within the body.
Study NCT04591106 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance elastography (MRE)
Description: Magnetic resonance elastography (MRE) is a non-invasive imaging technique that uses a gently vibrating transducer in combination with MRI to create detailed images and maps of the mechanical properties, such as stiffness, of tissues within the body.
Study NCT04591106 — intervention group
Intervention type: DEVICE
Intervention: Prototype MRE soft flexible passive transducer paddle
Description: The prototype device is provided to the investigators by Mayo Clinic under a Materials Transfer Agreement (MTA). The device is being used to promote comfort in the pediatric population; no formal data collection for regulatory submission is planned. The prototype device is smaller, softer, and more flexible than the commercial device and will be used where indicated by the subjects' size.
Study NCT05030233 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-Administered Touch Intervention
Description: The nurse-administered touch intervention is a bare-handed, comforting touch intervention administered during an episode of essential nursing care. The bedside nurse will cradle the infant's head with one hand, using the other hand to gently support the infant's lower body and legs in a flexed position. The touches will be administered for 1 minute at the start of the essential care episode, 30 seconds after the diaper change, and 1 minute at the conclusion of the care episode.
Study NCT05128591 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 18mg Oral Tablet
Description: AD-109 (Rivaroxaban 18mg) Oral Tablet
Study NCT05128591 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rivaroxaban 20 MG Oral Tablet
Description: AD-1091 (Rivaroxaban 20mg) Oral Tablet
Study NCT05611931 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo for selinexor
Description: Dose:60 mg (3 tablets); Dosage form: film-coated, immediate-release tablet of 20 mg each; Route of administration: oral
Study NCT04797988 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: eon® FR 1064 nm device
Description: The subject will be treatment area - flanks, will be treated with the eon device.
Study NCT04876352 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upper limb/handwriting exercises in an immersive virtual reality setting (VR-training)
Description: Progressively difficult multimodal physiotherapy under the augmented visual feedback induced by the VR. Participants will wear a head-mounted display and their upper limb movements during the training will be captured by a motion tracker. Patients will perform: repetition of movements of upper limb single joints (shoulder, elbow and wrist) under the augmented visual feedback provided by the use of VR in increasingly wide range of movement; active upper limb multi-joints movements under the augmented visual feedback provided by the use of VR (following trajectories designed in the virtual space - movement involving shoulder, elbow and wrist joints) and handwriting tasks and touch screen technology usage in VR context on a tablet and a smartphone.~30 minutes of exercises, 2 times a week, for 8 weeks.
Study NCT04876352 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Upper limb/handwriting exercises in a real setting (RS-training)
Description: Participants will perform progressively difficult multimodal physiotherapy in a real setting. Participants will be encouraged to perform their upper limb movements during the training in order to perform faster and ampler movements. They will perform: repetition of movements of upper limb single joints (shoulder, elbow and wrist) in increasingly wide range of movement under the feedback provided by therapist; active upper limb multi-joints movements under the feedback provided by the therapist (following trajectories designed on a table or on a blackboard - movements involving shoulder, elbow and wrist joints) and handwriting tasks and touch screen technology usage under the supervision of the therapist.~30 minutes of exercises, 2 times a week, for 8 weeks.
Study NCT04876352 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: No intervention
Description: Only baseline evaluations, without longitudinal assessment
Study NCT06159335 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: F-Fluciclovine radiotracer
Description: Participants will receive PET radiotracer and MRI
Study NCT06434246 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: pulley system exercise regimen
Description: The warm-up consists of gentle stretching and basic mobility exercises to prepare the muscles and joints for the activity. Following this, the main segment of the session involves specific exercises using the pulley system, designed to target and improve motor function, strength, and coordination of the upper limbs. The therapist will adjust the exercises according to each child's individual abilities and progression over time. The session concludes with a cool-down period involving light activities and relaxation techniques to ensure a gradual return to baseline physiological states.
Study NCT06434246 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: physical therapy program for CP
Description: Participants in the control group will attend physical therapy sessions twice per week. These sessions aim to maintain or improve physical functioning and manage the symptoms of cerebral palsy. Each session lasts approximately 45 to 60 minutes, These sessions include a variety of therapeutic exercises tailored to each child's needs but do not include the use of the pulley system. Typical activities might involve stretching, strengthening exercises, and manual therapy techniques to enhance joint mobility and muscle function.
Study NCT06434246 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: physical therapy program for CP
Description: Participants in the control group will attend physical therapy sessions twice per week. These sessions aim to maintain or improve physical functioning and manage the symptoms of cerebral palsy. Each session lasts approximately 45 to 60 minutes, These sessions include a variety of therapeutic exercises tailored to each child's needs but do not include the use of the pulley system. Typical activities might involve stretching, strengthening exercises, and manual therapy techniques to enhance joint mobility and muscle function.
Study NCT06071741 — intervention group
Intervention type: PROCEDURE
Intervention: Percutaneous Coronary Intervention
Description: balloon angioplasty, stent implantation, atherectomy, intravascular ultrasound.
Study NCT05251116 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: FreeStyle Libre
Description: FreeStyle Libre 2 continuous Glucose Monitoring System
Study NCT04693780 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured guide
Description: Structured guide
Study NCT04693780 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: List
Description: List
Study NCT06363019 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supporting at-risk Mothers Across perinatal period: a Randomized controlled Trial (SMART) mobile application
Description: The intervention is delivered through the SMART mobile application. It contains educational information in audio, visual, article format; on parenting, pregnancy and managing emotional well-being. There is also a peer support feature where participants can speak to experienced mothers via the SMART app. There is also a forum feature where participants can interact with other mothers.
Study NCT06230731 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen saturation
Description: Measure oxygen levels in 5 proximal colon mucosa locations.
Study NCT06230731 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen saturation
Description: Measure oxygen levels in 5 proximal colon mucosa locations.
Study NCT05360407 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Using mobile information application about before and after surgery
Description: The mobile application had three sections: Information forum (I), Personal forum (notebook and reminder) (II) and Ask the Researcher (messaging) (III). The information forum (Figure 2) is a section that enables patients to access related articles, pictures, and videos. The personal forum is a section that allows patients to create their notes and use the necessary reminders. Ask the researcher section allows patients to communicate with the researcher via messages.~The participants could download the mobile application with the name Breast Cancer Surgery Information Guide from the Google Play Store and install it on their phones. Users who were authenticated by the researcher were able to access the content with an e-mail and password.
Study NCT06010212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib Combined With Camrelizumab, Paclitaxel Liposome and Nedaplatin
Description: Phase Ib: Patients with advanced ESCC will be enrolled in a 3+3 dose escalation fashion, with projected enrolment of between 9-18 patients to determine RP2D. Once the RP2D is confirmed, the study will proceed to phase II.~fruquintinib: 3 mg, 4 mg, or 5 mg qd p.o., 2 weeks and 1 week, every 3 weeks ( dose exploration phases were performed sequentially from the 4 mg group, refer to the study design section for specific protocols); Camrelizumab: 200 mg I.V D1, every 3 weeks for treatment cycles; Paclitaxel liposomes: 135 mg/m2 i.v d1, administered every 3 weeks, up to 6 cycles; Nidaplatin: 70 mg/m2 i.v d1, administered every 3 weeks, up to 6 cycles. Chemotherapy is used for up to 6 cycles, followed by maintenance therapy with fruquintinib + Camrelizumab until disease progression or intolerable toxicity.~Phase II: Up to a total of 30 patients with advanced ESCC will be enrolled.
Study NCT05371561 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: reusable respirators
Description: Dentist wearing reusable respirator will examin the patient
Study NCT05371561 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: reusable respirators
Description: Dentist wearing reusable respirator will examin the patient
Study NCT05454813 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Wetness Sensing System Validation
Description: Participants will use the Wetness Sensing System in a simulated setting in the sitting, supine and side position (participants are randomized to either the left or right side position).
Study NCT05450913 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Priformis intramuscular injection with %2 lidocain
Description: Priformis intramuscular injection will be administered with 5 cc 2% lidocaine, accompanied by a nerve stimulator under ultrasound guidance
Study NCT05311020 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo drink
Description: consume 1 bottle per day
Study NCT05311020 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Pitaya Ovule Extract Drink
Description: consume 1 bottle per day
Study NCT04917614 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous Electrical Acupoint Stimulation
Description: Transcutaneous Electrical Acupoint Stimulation
Study NCT04894097 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: radial extracorpeal shock wave
Description: Swiss DolorClast® Master - Shockwave Therapy System will be used to apply the radial extracorporeal shock wave. It consists of master console, Evo Blue hand-piece, 15mm and 36mm interchangeable contact heads (applicators), contact gel, cart, and external compressor
Study NCT04894097 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: radial extracorpeal shock wave
Description: Swiss DolorClast® Master - Shockwave Therapy System will be used to apply the radial extracorporeal shock wave. It consists of master console, Evo Blue hand-piece, 15mm and 36mm interchangeable contact heads (applicators), contact gel, cart, and external compressor
Study NCT04920266 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smart Cap, running and fitness exercisers only
Description: Bottle cap
Study NCT04920266 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sweat Patch, all subjects- running, fitness, cycling
Description: Regional contralateral forearm patch
Study NCT04920266 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Reference sweat patch, all subjects - running, fitness, cycling
Description: Regional contralateral forearm patch
Study NCT04920266 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Bottle Scale, all subjects - running, fitness, cycling
Description: Bottle weight