AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06065631 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Prescription slip
Description: Children with uncorrected/under-corrected refractive error will be provided with an eyeglasses prescription and letter to parents, but all of them will get eyeglasses at the end of the trial
Study NCT05427370 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Revascularization by PCI
Description: Contemporary, State-of-the-art PCI techniques will be encouraged in STICH3C, based on the most recent evidence and clinical practice guidelines recommendations. The best practices to be followed include the use of physiological and intravascular guidance, new-generation drug-eluting stents or scaffolds, rotational or orbital atherectomy for extensive calcifications, recommended bifurcation techniques, chronic total occlusion for viable segments by experienced operators, and trans-radial access.Planned temporary ventricular support is permitted by experienced operators when deemed indicated.
Study NCT05427370 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Revascularization by CABG
Description: The surgical revascularization strategy will be tailored according to the individual patient's coronary anatomy, left ventricular remodeling, aortic atherosclerosis, co-morbidities, local expertise, and surgical judgement. An internal thoracic artery will be used to graft the left anterior descending in all cases. Multi-arterial grafting may be considered in patients without significant co-morbidities and with expected limited vasopressor use, or in patients without saphenous conduits. Choice of on- vs. off-pump surgery is influenced by LV size, associated valvular disease, and aortic atherosclerosis, as well as surgeon experience, but on-pump surgery is recommended routinely. The use of adjunctive intra-aortic balloon support or other cardiac support is not routinely recommended in stable patients; the intra-aortic balloon support is the first line mechanical support.
Study NCT06568705 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Moderate hypofractionated Radiation Treatment
Description: The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 43.5Gy in 15 fractions in patients who underwent breast conserving surgery or mastectomy.
Study NCT06568705 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Ultrafractionated Radiation Treatment
Description: The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 26Gy in 5 fractions in patients who underwent breast conserving surgery or mastectomy.
Study NCT06578234 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adenosine
Description: Standard dose 140 μg/kg/min and high dose 210 μg/kg/min adenosine
Study NCT05033288 — intervention group
Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical records are reviewed
Study NCT05033288 — intervention group
Intervention type: OTHER
Intervention: Quality-of-Life Assessment
Description: Complete quality of life questionnaires
Study NCT04840355 — intervention group
Intervention type: DRUG
Intervention: Sintilimab Injection
Description: The recommended dose for intravenous infusion is 200 mg on day 1.Courses repeat every 21 days for up to 6 months in the absence of disease progression or unacceptable toxicity.
Study NCT05725876 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ustekinumab
Description: Patients not on therapy and patients on therapy will undergo fluorescence molecular imaging.
Study NCT06634966 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Segmentectomy
Description: The lungs are divided into multiple lobes. A segmentectomy involves the removal of part of one of the lobes of the lung to entirely remove a cancerous tumor. segmentectomy can preserve more normal functional lung tissues.
Study NCT05844293 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: FXI-GalNAc-siRNA
Description: FXI-GalNAc-siRNA solution for injection
Study NCT06635161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Trancranial pulse stimulation (without a stand-off device)
Description: A single session of TPS will be performed, applying 1000 pulses in the session (single ultrashort (3 μs) ultrasound pulses, 0.2 mJ mm-2, 4 Hz pulse frequency). No stand-off device will be used to target dorsal anteior cingulate cortex.
Study NCT06635161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial pulse stimulation (with Neurology stand-off device)
Description: A single session of TPS will be performed, applying 1000 pulses in the session (single ultrashort (3 μs) ultrasound pulses, 0.2 mJ mm-2, 4 Hz pulse frequency). A Neurology stand-off device will be used to target the anterior insula cortex.
Study NCT06635161 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial pulse stimulation (with a sham stand-off device)
Description: A single session of TPS will be performed, applying 1000 pulses in the session (single ultrashort (3 μs) ultrasound pulses, 0.2 mJ mm-2, 4 Hz pulse frequency). A sham stand-off device will be used to target vertex.
Study NCT05844293 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Placebo
Description: Saline
Study NCT06362538 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: International Physical Activity Questionnaire
Description: Assessments of physical activity level and functional capabilities (aerobic capacity, muscular strength and power, flexibility
Study NCT06362538 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Six minute walking test
Description: The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity.
Study NCT06362538 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: SF-36, Euro-Qol 5D-5L, Perceived stress scale-10, Pittsburgh Sleep Quality Index, Depression Anxiety Stress scale- 21.
Description: Evaluation of the quality of life, the psychological sphere (anxiety, stress, depression) and the quality of sleep
Study NCT06362538 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: MEDAS
Description: Evaluation of adherence to the Mediterranean diet
Study NCT06362538 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Intima-media thickness (IMT)
Description: Bmode ultrasonography
Study NCT06362538 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood sampling
Description: Measurement of parameters for defining cardiovascular risk and biomarkers.
Study NCT06362538 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Stool Sample Culture Test
Description: Evaluation of Gut Microbiota
Study NCT06123169 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibioprophylaxis (Piperacillin-tazobactam)
Description: antibiotic prophylaxis during surgery
Study NCT06123169 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5 days Antibiotherapy (Piperacillin-tazobactam)
Description: 5 days Antibiotherapy from surgery
Study NCT06210113 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Stress Reduction
Description: An 8-week Mindfulness-based stress reduction training programme
Study NCT06418022 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Trendelenburg positioning VTI
Description: There are essentially two arms, whereby the patients is being compared to themselves. The intervention arm is the same patient undergoing TP from the baseline supine position to determine the change in VTI after subjecting to TP.~We will be using a Sonosite PX ultrasound system, which is intended for diagnostic ultrasound imaging or fluid flow analysis of the human body and, more specifically, for our echocardiographic measurements of velocity time integral (VTI; surrogate for stroke volume and cardiac output). The Sonosite PX is a general-purpose ultrasound system intended for use by qualified physicians and healthcare professionals, for evaluation by ultrasound imaging or fluid flow analysis of the human body. This is an FDA-cleared (510K# K200964) commercial device legally marketed in the United States that is being used in accordance with labeling.
Study NCT06089564 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Skit video, Pictorial, Sign language
Description: Three oral health educational intervention groups, group A (skit video), group B (pictorial) and group C (sign language) by using Sequentially Numbered Sealed Opaque Envelopes (SNOSE). Children picked a sealed envelope randomly and assigned to oral health education intervention group A, B and C. Participants in group A were assigned a skit video method of oral hygiene intervention and shown 5 minute video on what to eat and how to brush their teeth. The video included that what is good and bad for teeth, and how to brush which includes method, time and duration of tooth brushing. Participants assigned to group B and C was provided same instructions for tooth brushing and eating habits in the form of pictures and sign language respectively. The children of Group A received instructions in the form of laminated cards and asked to take with them at home. Participants in group C were received instructions in sign language in the presence of teacher.
Study NCT06311916 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC + Tirelizumab +lenvatinib +liver resection
Description: Patients in the neoadjuvant group received two cycles of neoadjuvant hepatic arterial infusion chemotherapy (HAIC, adoption of the FOFOLX6 program, Folinic acid+5-fluorouracil+Oxaliplatin, 21 days between second HAIC treatments with a window of ±3 days) + Tirelizumab (First treatment with Tirelizumab was started 0-1 days after HAIC, 200 mg IV, followed by a second treatment 21 days later)+ lenvatinib (Oral 8 mg or 12mg once a day depending body weight). Assessment of tumor status and surgical safety after receiving neoadjuvant therapy, and eligible patients then underwent surgical resection.
Study NCT06311916 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: liver resection
Description: Direct liver resection or laparoscopic liver resection depending on tumor status.
Study NCT06534593 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard medical treatment
Description: Standard medical treatment
Study NCT06534593 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lumbar Traction
Description: Lumbar traction using traction table
Study NCT06534593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mckenzie Extension Protocol
Description: Mckenzie Extension Exercises
Study NCT06534593 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Interferential Therapy
Description: Interferential Therapy for 20 minutes
Study NCT06534593 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heat Therapy
Description: Heat Therapy for 20 minutes
Study NCT06534593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sustained Natural Apophyseal Glides (SNAGs)
Description: 3-5 reptations of Mulligan's lumbar extension Sustained Natural Apophyseal Glides (SNAGs)
Study NCT05779683 — intervention group
Intervention type: DEVICE
Intervention: Caretaker Device placement
Description: placement of the device on the postoperative cardiac surgery patient that has a pulmonary artery catheter for comparison readings
Study NCT05666635 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: LTC004
Description: LTC004 Phase I:Participants will be allocated to one of the following dose groups: 3, 15, 45, 90, 180，270,360 and 450 ug/kg, and receive a treatment of LTC004 followed by 21 days of dose limited toxicity (DLT) observation period.~Phase Ib indication exploration~Other Name: LTC004 for Injection
Study NCT06383754 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Clareon
Description: Monofocal intraocular lens
Study NCT06383754 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Tecnis 1
Description: Monofocal 1 Piece intraocular lens
Study NCT05484622 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vorasidenib
Description: Administered orally as tablets.
Study NCT05484622 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Administered as IV infusion.
Study NCT05794243 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3493269
Description: Administered orally.
Study NCT05794243 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Caprate (C10)
Description: Administered orally.
Study NCT05794243 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Salcaprozate Sodium (SNAC)
Description: Administered orally.
Study NCT05422040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry needling
Description: Invasive treatment will be performed on the most symptomatic lumbar iliocostalis muscle.
Study NCT05422040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tecartherapy treatment
Description: Treatment will be carried out with deep thermotherapy in the lumbar region.
Study NCT05112172 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen Therapy
Description: Oxygen Therapy in patients developing an altitude related adverse health effect (ARAHE) during 30h exposure to 2500m of high altitude
Study NCT04479176 — intervention group
Intervention type: PROCEDURE
Intervention: Transnasal Sphenopalatine Ganglion Block
Description: In transnasal approach, several authors described the traditional technique using sterile 10cm cotton tipped applicators that are dipped in the chosen anesthetic and then advanced along the superior border of the middle turbinate, until it reaches the posterior wall of the nasopharynx. Some other techniques had described dripping one or two ml of the anesthetics into the nostril.
Study NCT05331131 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Topical
Description: Ketamine hydrochloride in mouthwash form
Study NCT05466123 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Simulated travel destination or activity of the participants choosing that would otherwise be inaccessible
Study NCT06367621 — intervention group
Intervention type: DEVICE
Intervention: iStatis Syphilis Antibody Test
Description: 1500 stored samples (plasma/serum) will be tested in a routine testing environment using the iStatis Syphilis Antibody Test diagnostic device. Results of tests will not be used for patient management decisions (observaltional).
Study NCT05147415 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inactive comparator
Study NCT05147415 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tesomet
Description: Fixed-dose combination
Study NCT05147415 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tesomet
Description: Fixed-dose combination
Study NCT05260567 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise and Lifestyle Change
Description: Patients will undergo to weekly phone call/videoconference for 12 weeks and discuss the behaviour change.~They also will undergo to home-based exercise training will be performed twice a week for 12 weeks via Zoom (up to 5 patients per session). Each session will be comprised of warm-up (10 min), the main part (15 to 20 min), and cooldown (5 to 10 min). The training aims to develop resistance, aerobic and functional capacity such as getting up, walking, pulling, pushing, throwing, transferring body weight or external loads. In addition, patients will be encouraged to increase their physical activity. Patients will be provided with a Fitbit device to monitor their step count and will be recommended to increase their previous week's average step count by 10%.
Study NCT05260567 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Exercise and Lifestyle Change
Description: Patients will undergo to weekly phone call/videoconference for 12 weeks and discuss the behaviour change.~They also will undergo to home-based exercise training will be performed twice a week for 12 weeks via Zoom (up to 5 patients per session). Each session will be comprised of warm-up (10 min), the main part (15 to 20 min), and cooldown (5 to 10 min). The training aims to develop resistance, aerobic and functional capacity such as getting up, walking, pulling, pushing, throwing, transferring body weight or external loads. In addition, patients will be encouraged to increase their physical activity. Patients will be provided with a Fitbit device to monitor their step count and will be recommended to increase their previous week's average step count by 10%.
Study NCT05646953 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Facial Beauty Oil
Description: Mode of Usage Step 1- Wash face, pat dry Step 2 - Gently massage 2-3 drops of Vasu Facial Beauty Oil over the face and neck till it gets absorbed and keep it overnight.~Step 3 - Use it for 60 days Frequency - Daily before going to bed. Route of Administration - Topical
Study NCT04774367 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Order of forceps : First standard biopsy forceps and second large capacity biopsy forceps
Description: Order of forceps : First standard biopsy forceps and second large capacity biopsy forceps
Study NCT04774367 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Order of forceps : First large capacity biopsy forceps and second standard biopsy forceps
Description: Order of forceps : First standard biopsy forceps and second large capacity biopsy forceps
Study NCT05850234 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GC012F (AZD0120)
Description: GC012F (AZD0120) is a BCMA/CD19 dual CAR product under investigation for the treatment of patients with RRMM.
Study NCT05968469 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aerobic exercises with cycling ergometry
Description: A total of 20 sessions of high-intensity interval (HIIT) aerobic exercise program will be applied to the patients using a bicycle ergometer, five days a week and once a day for four weeks. And then, it was planned to perform stretching exercises for the cervical, thoracic and lumbar regions and posture exercises accompanied by a specialist physiotherapist.~The patients will be evaluated by the physician for a total of 3 times at the beginning of the treatment, at the end of the treatment (4th week) and at the 12th week after the start of the treatment. All patients will be evaluated for the parameters in the patient evaluation form, and blood samples taken between 08:00 and 10:00 in the morning and Calprotectin, Visfatin, Leptin, IL-33 serum levels will be measured with the ELISA kit.
Study NCT05968469 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stretching exercises
Description: Stretching exercises for the cervical, thoracic and lumbar regions and posture exercises were planned to be performed with the expert physiotherapist.~The patients will be evaluated by the physician for a total of 3 times at the beginning of the treatment, at the end of the treatment (4th week) and at the 12th week after the start of the treatment. All patients will be evaluated for the parameters in the patient evaluation form, and blood samples taken between 08:00 and 10:00 in the morning and Calprotectin, Visfatin, Leptin, IL-33 serum levels will be measured with the ELISA kit.
Study NCT04467723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab is given as an intravenous infusion at 1200 mg every 3 weeks. Pirfenidone is taken by mouth 3 times a day with the dose increasing every 2 week until day 30
Study NCT06125392 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary physiology assessment
Description: Resting distal coronary to aortic pressure ratio, resting flow ratio, fractional flow reserve, Coronary Flow Reserve and Microvascular resistance using the thermodilution method and papaverin or adenosine, Resting distal coronary to aortic pressure ratio, resting flow ratio, fractional flow reserve, Coronary Flow Reserve and Microvascular resistance using the thermodilution method and acetylcholine.
Study NCT06465641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylphenidate Hydrochloride
Description: Methylphenidate hydrochloride in capsules
Study NCT06465641 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Microcrystalline cellulose in capsules
Study NCT06584383 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Exablate MRgFUS subthalamotomy
Description: Exablate MRgFUS subthalamotomy for Parkinson's Disease
Study NCT06584383 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exablate MRgFUS subthalamotomy
Description: Exablate MRgFUS subthalamotomy for Parkinson's Disease
Study NCT06584383 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Best Medical Treatment
Description: Subjects will be managed according to conventional therapeutic guidelines (i.e., best medical treatment) for Parkinson's Disease
Study NCT04940065 — intervention group
Intervention type: OTHER
Intervention: Kesimpta
Description: Prospective observational cohort study. There is no treatment allocation.
Study NCT04173650 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGLE 102
Description: Exosomes from MSCs up to six administrations
Study NCT05445427 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: vagal nerve stimulator
Description: Non-invasive vagus nerve stimulator
Study NCT06481917 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Advance care plan
Description: Scheduling of 2 home visits by an expert nurse in the month following the return home and proposal to carry out an advance care plan.
Study NCT06481917 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ergonomic analysis
Description: Ergonomic analysis throughout the intervention
Study NCT06481917 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evaluation of intervention acceptability
Description: Evaluation of intervention acceptability after each home visit with patients and caregivers using a questionnaire