AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04784520 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HA121-28 tablets
Description: HA121-28 600 mg, po, QD×21 days, every 4 weeks (28 days)
Study NCT04720664 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SM-88
Description: * SM-88, Two 230 mg capsules taken orally twice daily (920 mg daily).~* Methoxsalen, One 10 mg capsule taken orally once daily.~* Phenytoin, One 50 mg tablet taken orally once daily.~* Sirolimus, One 0.5 mg tablet taken orally once daily.
Study NCT05994859 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SIRT
Description: The patients will receive 1-2 sessions of SIRT. If the patients have invasive tumors, extensive liver involvement or vascular invasion, systematic treatment will be added.
Study NCT06254677 — intervention group
Intervention type: OTHER
Intervention: Retrospective review of histological features
Description: Correlate histopathology characteristics of acute kidney injury with molecular signatures, kidney function and aetiology of acute kidney injury to derive clinically validated scoring system for acute kidney injury and acute tubular injury
Study NCT03186456 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#)
Description: Allogeneic umbilical cord mesenchymal stem cells will transfusion into by forearm intravenous transplantation, 0.5 - 1 \*10\^6/kg. once a month, total 3 times.
Study NCT03186456 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin Tablet
Description: Drug: Aspirin Tablet, 100 mg/d
Study NCT03186456 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Aspirin Tablet
Description: Drug: Aspirin Tablet, 100 mg/d
Study NCT05611593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOL100
Description: FOL100 lotion
Study NCT05611593 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propecia 1Mg Tablet
Description: Oral Finasteride
Study NCT05283070 — intervention group
Intervention type: OTHER
Intervention: Questionnaires, physical tests, and heart rate variability measures
Description: The 2MWT will be conducted in an unobstructed hallway with patients being asked to walk at moderate intensity (brisk walk) for the duration of the activity (2 minutes). The amount of distance in metres will be recorded.~The EMLi movement consists of pushing a 2kg weighted ball from the chest level forward, and then raising the ball overhead, before returning it to the starting position (Figure 1). The number of repetitions done at moderate intensity will be recorded after 60 seconds.~HRV and questionnaires previously listed
Study NCT04837352 — intervention group
Intervention type: OTHER
Intervention: Study of the role of sociocognitive factors
Description: Questionnaires
Study NCT04923594 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mazindol extended release
Description: Dosed orally, once daily for up to 3 weeks
Study NCT04923594 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dosed orally, once daily for up to 4 weeks.
Study NCT05042726 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cTBS First
Description: Continuous θ-burst stimulation (cTBS) is characterized by plexus stimulation. The stimulation intensity was 80% resting motor threshold (RMT) at 50Hz of intra plexus pulse while the frequency of inter plexus pulse is 5Hz, the duration was 33.2s, and the number of stimulation pulses was 600. Two groups of stimulation were repeated in each cerebellar dentate nucleus with an interval of 5 min in each group.
Study NCT05042726 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pseudo-stimulation First
Description: The transcranial magnetic stimulator operating system has a built-in control group option, in which the stimulation parameters are set consistent with the research group, which can realize the operation of only sound without stimulation.
Study NCT05269121 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Phage Therapy
Description: Patient will undergo a DAIR procedure. After the DAIR, phage therapy will be administered in conjunction with antibiotic treatment.
Study NCT04896970 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Concert
Description: A musical show in a closed hall, lasting for about 2 hours, in respects of safety measure (masks, hydroalcoholic gel, etc...) with approximately 200 participants.
Study NCT05446831 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baricitinib
Description: Oral baricitinib was given at a dose of 4 mg daily. The decision to initiate rescue therapy was made after assessment of the extent of bleeding, patient preferences, lifestyle and activity, the complications of specific therapies, comorbidities that predisposed patients to bleeding and the tolerance of side effects. If a platelet count over 300,000/μL was observed for two consecutive tests at least 2 weeks apart, baricitinib treatment was interrupted.
Study NCT05672667 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intravenous oxytocin
Description: Oxytocin given by intravenous route
Study NCT05672667 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intranasal oxytocin
Description: Oxytocin given by intranasal administration
Study NCT04894955 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MARIA
Description: After consent has been given, the participant's breast will be fitted by the operator using a clear plastic cup to ascertain their corresponding MARIA® cup insert size. Once this has been determined, participants will be required to lie prone with their breast pendent through an aperture in the MARIA® participant bed. The cup insert will contain a layer of coupling fluid. The hemispherical cup inserts and array are brought into contact with the breast. A scan sequence comprising of two complete scan rotations will then be performed, which takes around 5 minutes. The participant will then be assisted to adjust their positioning, and the scan sequence performed on the other breast.
Study NCT04293016 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Support as usual
Description: This group receives current best practice which includes participation in ICU support groups and provision of community support resources
Study NCT04293016 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem solving therapy
Description: This group will receive one on one therapy based on identifying stressors and solutions to those stressors
Study NCT04293016 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ICU diary
Description: This group will be provided with a structured written diary that includes identification of stressors and development of solutions to those stressors
Study NCT06519656 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mazdutide
Description: In the initial 4 weeks, the subjects are given Mazdutide 2mg once weekly. If well tolerated, the dosage is increased to 4mg once weekly for another 4 weeks. If still well tolerated, the dosage is further increased to 6mg once weekly and maintained for the ensuing 16 weeks.
Study NCT05675449 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elranatamab
Description: BCMA-CD3 bispecific antibody
Study NCT05675449 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib
Description: proteasome inhibitor
Study NCT05675449 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Maplirpacept
Description: CD47-SIRP alpha-directed
Study NCT06164769 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation
Description: In the pancreatic enucleation, Kocher Maneuver was routinely performed at first. Then free the left side of the abdominal trunk and superior mesenteric artery, loose tissues easy to free.After Kocher Maneuver and other surgical procedures, the abdominal trunk and superior mesenteric artery exposed. Before resection of pancreatic tumors, a vascular occlusion clamp clip was used to block the root of both the abdominal trunk and superior mesenteric artery to control the pancreatic blood flow.
Study NCT05105763 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Sequential switched feedback training on the knee and the hip (Condition A)
Description: Condition A will include four 6-mins training blocks: 2-mins knee joint feedback-on, 2-mins hip joint feedback-on, and 2-mins feedback-off. Training with feedback on will occur as follows: The subject will walk on the treadmill and try to achieve the target hip and/or knee flexion pattern shown on the feedback interface. Training with feedback off will occur as follows: The subject will walk on the treadmill and try to maintain the pattern without any form of visual or verbal feedback.
Study NCT05105763 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Feedback training on the knee alone (Condition B)
Description: Condition B will include four 6-mins training blocks: 4-mins knee joint feedback-on and 2-mins feedback-off. Training with feedback on will occur as follows: The subject will walk on the treadmill and try to achieve the target hip and/or knee flexion pattern shown on the feedback interface. Training with feedback off will occur as follows: The subject will walk on the treadmill and try to maintain the pattern without any form of visual or verbal feedback.
Study NCT04937504 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: STAIR-PC Group
Description: Skills Training in Affective and Interpersonal Regulation for Primary Care (STAIR-PC) is a face-to-face, individual, brief (5 session) therapy adapted from the STAIR program. STAIR-PC is an appropriate treatment for individuals who have experienced traumatic stressors, and addresses symptom targets by teaching skills to improve coping with emotions and strengthen interpersonal relationships.
Study NCT04937504 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WebSTAIR Group
Description: WebSTAIR is a web-based self-help program adapted from the STAIR program for individuals who have experienced traumatic stressors. WebSTAIR contains 10 self-guided interactive modules that teach skills to improve coping with emotions and strengthen interpersonal relationships.
Study NCT06369714 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Concerta
Description: Methylphenidate Hydrochloride Extended-Release Tablets with the following specifications: 18mg dosage, oral administration, once a day for a duration of 8 weeks.
Study NCT06369714 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Concerta
Description: Methylphenidate Hydrochloride Extended-Release Tablets with the following specifications: 18mg dosage, oral administration, once a day for a duration of 8 weeks.
Study NCT06369714 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital therapeutics
Description: 30 sessions of digital therapeutics, each lasting 30 minutes, will be conducted with a frequency of once every 1-2 days over an 8-week period.
Study NCT05951465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: esketamine dose will be 0.3 mg/kg. Propofol dose for the first patient will be 2.5 mg/kg. Doses for the subsequent patients will increase or decrease by 0.8 mg/kg using the Dixon Up and Down method.
Study NCT05951465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: esketamine dose will be 0.6 mg/kg. Propofol dose for the first patient will be 2.0 mg/kg. Doses for the subsequent patients will increase or decrease by 0.4 mg/kg using the Dixon Up and Down method.
Study NCT05951465 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: propofol
Study NCT05228366 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heel warming with mild thermofor group
Description: Heel warming will be applied to the newborns in the ıntervention group 1 with a thermofor containing 34-37C warm water for 5 minutes before the heel blood collection procedure. During the procedure, the general condition of the newborn and the changes in his skin will be observed closely. Heel blood collection will be performed by following the standard procedure steps that are routinely applied in the service
Study NCT05228366 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heel warming with hot thermofor group
Description: Heel warming will be applied to the newborns in the ıntervention group 2 with a thermofor containing 38-40C warm water for 5 minutes before the heel blood collection procedure. During the procedure, the general condition of the newborn and the changes in his skin will be observed closely. Heel blood collection will be performed by following the standard procedure steps that are routinely applied in the service
Study NCT05228366 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Ineffective heel warming with thermofor group
Description: Ineffective heel warming will be applied to the newborns in the control group with a thermofor containing 28C warm water for 5 minutes before the heel blood collection procedure. During the procedure, the general condition of the newborn and the changes in his skin will be observed closely. Heel blood collection will be performed by following the standard procedure steps that are routinely applied in the service.
Study NCT04019262 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiation Therapy
Description: Radiation
Study NCT04019262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Temozolomide Oral Product
Description: Oral Temozolomide (150mg/m\^2 or 75 mg/m\^2)
Study NCT05293730 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eFRIEND
Description: eFRIEND is a 6-month CWH-led intervention. All CHW will be part of the research team to ensure successful recruitment and interaction with patients, and all CHW will be certified and have participated in the North Carolina Community Health Worker Standardized Core Competency Training.
Study NCT05293730 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Routine treatment in primary care
Study NCT05372926 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high flow nasal canulae
Description: high flow nasal canulae is a oxygen therapy technic which allows the administration of warmed and humidified oxygen with a flow up to 50L/Min and a monitored FiO2. Physiological previous studies reported various effects of this technic especially on work of breathing. In our study the investigators aim to test this physiological property during exercise.
Study NCT05372926 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ventury mask
Description: Ventury mask is a oxygen therapy technic which allows the administration with a mask of oxygen with a flow up to 15L/Min and a monitored FiO2.
Study NCT05810753 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SPOONful
Description: Participants will be asked to consume two ONS daily, in addition to their regular diet, for three weeks. Participants will be asked to consume one ONS with their breakfast, and one with lunch.
Study NCT04769622 — intervention group
Intervention type: PROCEDURE
Intervention: Non-surgical periodontal treatment
Description: all included patients will be subjected to non-surgical periodontal therapy
Study NCT04769622 — intervention group
Intervention type: OTHER
Intervention: Questionnaires
Description: All patients will be asked to complete a set of questionnaires regarding:~* adherence to Mediterranean Diet;~* sleep quality;~* physical activity;~* perceived stress.
Study NCT05020379 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Perioperative and postoperative multimodal analgesia
Description: Patients will receive standard multimodal analgesia comprising paracetamol, tenoxicam, and tramadol.~The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). NRS scores for pain and postoperative opioid consumption will be evaluated at 15th and 30th minutes, 1st, 2nd, 6th, 12th, 24th hours, 2nd day.
Study NCT05020379 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Perioperative and postoperative multimodal analgesia
Description: Patients will receive standard multimodal analgesia comprising paracetamol, tenoxicam, and tramadol.~The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). NRS scores for pain and postoperative opioid consumption will be evaluated at 15th and 30th minutes, 1st, 2nd, 6th, 12th, 24th hours, 2nd day.
Study NCT05020379 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ESP Block
Description: Patients in the ESPB group will be placed in a sitting position. A convex probe ultrasound transducer will be placed in a longitudinal parasagittal orientation approximately 3 cm lateral to the spinous process. Local anesthetic (20 ml 0.25% bupivacaine) will be injected bilaterally into the fascial plane on the deep face of the erector spinae muscle. Standard perioperative and postoperative analgesia protocol will be given and postoperative pain levels will be determined by Numerical Rating Scale (NRS). NRS scores for pain and postoperative opioid consumption will be evaluated at 15th and 30th minutes, 1st, 2nd, 6th, 12th, 24th hours, 2nd day.
Study NCT05459376 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercises and dry cupping
Description: Participants in the intervention group will receive an assessment, classification as to MDT syndrome and indication of the preferred direction of movement, whether flexion, extension or lateral displacement of the spine
Study NCT05122650 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JZP385
Description: JZP385 capsules will be administered orally (PO) once daily in the morning on an empty stomach for 12 weeks.
Study NCT06190054 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MERAMIRT
Description: MERAMIRT®, a class IIa medical device, is indicated for hydration and lubrication of the ocular surface under conditions of eye disorders caused by environmental, visual and mechanical stress, also due to asthenopia and accommodation effort. The main component of MERAMIRT® are Hydroxypropyl-methylcellulose (HPMC 0.3%) and Inositol (0.1%).~HPMC has the property of moisturizing and lubricating the eye. Inositol is used with an antioxidant role
Study NCT05122650 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules will be administered orally (PO) once daily in the morning on an empty stomach for 12 weeks.
Study NCT05459376 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Exercises and dry cupping
Description: Participants in the intervention group will receive an assessment, classification as to MDT syndrome and indication of the preferred direction of movement, whether flexion, extension or lateral displacement of the spine
Study NCT05148871 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Spikogen/Covax-19
Description: Spikogen/Covax-19 is a recombinant spike protein vaccine formulated with Advax-CpG55.2 adjuvant
Study NCT04952623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rotator Cuff Related Shoulder Pain E-Learning Program
Description: The RCRSP e-learning program is designed according to the ADDIE Instructional Design Model in light of current literature.
Study NCT04952623 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rotator Cuff Related Shoulder Pain E-Learning Program
Description: The RCRSP e-learning program is designed according to the ADDIE Instructional Design Model in light of current literature.
Study NCT05133830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obeticholic acid
Description: OCA will be administered
Study NCT05133830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linerixibat
Description: Linerixibat will be administered
Study NCT05312827 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Training Intervention and Program of Support (TIPS) for fostering the adoption of family-centred telehealth interventions in pediatric rehabilitation
Description: The proposed pre-post study will evaluate the implementation and effectiveness of a Training Intervention and Program of Support (TIPS) to enhance the adoption of family-centred telehealth in pediatric rehabilitation centres across Canada. TIPS is a multifaceted intervention, comprised of the following: 1) a 10-hour intensive training program offered to participating therapists at each site over a one-month period, including 4 hours of self-paced learning modules and a 6-hour mandatory interactive webinar; and 2) an 11-month program of support which is composed of monthly mentoring meetings at each site led by the local therapist champion, and a national virtual community of practice facilitated by 3 national knowledge brokers - an occupational therapist, a physiotherapist and a speech-language pathologist - experienced in family-centred telehealth in pediatric rehabilitation, offered simultaneously to all participating therapists across Canada.
Study NCT06240767 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Granulocyte infusion
Description: The number of single granulocytes per infusion was 2.0-5.0×10\^10, with an interval of 2±1 day and 5 continuous infusions.
Study NCT04199702 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Same day discharge
Description: Patients will be discharged the same day they undergo catheter ablation of atrial fibrillation.
Study NCT05204303 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 24-hour pH-impedance monitoring
Description: Ambulatory transnasal reflux device to detect reflux events in the oeosphagus and pharynx.
Study NCT05204303 — intervention group
Intervention type: OTHER
Intervention: Symptom questionnaires
Description: Reflux Symptom Index (RSI) Gastroesophageal Reflux Disease Questionnaire (GERDQ) Short-form Esophageal Hypervigilance and Anxiety Scale (SF-EHAS)
Study NCT05204303 — intervention group
Intervention type: OTHER
Intervention: ROME IV Diagnostic Questionnaire
Description: A symptom-based questionnaire used to diagnose disorders of gut-brain interaction (DGBI)