AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06486363 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin combined with clopidogrel
Description: Participants in this group shall take Aspirin (100 mg/day) + clopidogrel (75 mg/day) for at least 5 days before receiving stent-assisted coil embolization, and take same medication for 6 months after endovascular treatment
Study NCT06486363 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin combined with half-dose ticagrelor
Description: Participants in this group shall take Aspirin (100 mg/day) + half dose of ticagrelor (45 mg, 12 hours/time), at least for 3 days before receiving stent-assisted coil embolization, and take same medication for 6 months after endovascular treatment
Study NCT05770258 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The novel electrolyzed water spray
Description: Study staff will use the novel electrolyzed water spray device and spray for approximately 5 minutes on the participant's diseased area until half a bottle (200ml) of water is used. The patients use electrolyzed water to treat the diseased area, two times a day, for 10 days. The trial consists of 10 study visits (day 1-day 10). The relief of mild periodontitis evaluation and adverse event assessments will be performed at each visit. Safety analysis will be assessed based on the reports of adverse events during the study.
Study NCT06513013 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: transversus abdominis plane (TAP) block in cesarean section
Description: .an intravenous (IV) access will be secured . Standard ASA monitoring will be instituted which include(SpO2), ECG and (NIBP) . At the end of surgery , a bilateral USG-guided TAP block will be carried out under strict aseptic precautions, and 20 mL of study solution was injected into each side. After draping the abdominal region between the 12th rib and anterior superior iliac crest with the umbilicus in the center, the external oblique muscle, internal oblique muscle, transversus abdominis muscle , and their fascia will be located beneath the skin and subcutaneous tissue using a linear high-frequency probe 6-13 Megahertz of the SonoSite Micromax machine. A 22-gauge spinal needle will be advanced using the in-plane technique at the anterior axillary line, and the precise position of the needle tip between the internal oblique and transverse abdominis muscle will be visualized. To expand the plane, 2 mL of normal saline will be administered.
Study NCT06513013 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulfate
Description: 25ml volume on each side (20ml of 0.25% bupivacaine plus 5ml of normal saline containing 250 mg of MgSO4) to keep the total volume the same in both group
Study NCT05183542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bone scan
Description: Persons to be operated on for lumbar arthrodesis by the neurosurgery team of the Nancy CHRU and respecting the eligibility criteria (including a score of neuropathique pain scale \< 4, see non-inclusion criteria), will be proposed to participate in the study neuropathic pain If they give their oral agreement to the neurosurgeon, a request for a bone scan will be sent to the nuclear medicine department of the Nancy-Brabois Hospital. The patients will fill pain scales before and after surgery (ODI and NS)
Study NCT05887700 — intervention group
Intervention type: DEVICE
Intervention: CeraFlex™ Atrial Septal Defect (ASD) Closure System
Description: The CeraFlex™ ASD Occluder have two types of occluders, CeraFlex™ ASD Occluder and CeraFlex™ Multi-fenestrated (Cribriform) ASD Occluder. The CeraFlex™ ASD Occluder is percutaneous, transcatheter closure devices for the non-surgical closure of atrial septal defects.
Study NCT06229132 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: LGBTQ-affirmative CBT for transgender individuals
Description: The intervention addresses unique stressors encountered by transgender individuals due to discrimination and lack of adequate and affirming healthcare resources.
Study NCT04995523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD2936
Description: Anti-TIGIT/Anti-PD-1 Bispecific Antibody
Study NCT05320055 — intervention group
Intervention type: PROCEDURE
Intervention: robotic repair
Description: robotic assisted retromuscular hernia repair
Study NCT06368440 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: Participants will receive AZD6793 single dose as oral suspension.
Study NCT06368440 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD6793
Description: Participants will receive AZD6793 multiple doses daily as oral suspension.
Study NCT06368440 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive matching doses of placebo as oral suspension.
Study NCT06524063 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Survivin-loaded dendritic cell injection
Description: The injections will be given on days 0, 14, and 28. The administration will involve both intradermal (ID) and intravenous (IV) routes.
Study NCT05179967 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WeFlow-JAAA Stent Graft System
Description: WeFlow-JAAA Stent Graft System consists of abdominal main body of inner embedded stent graft , abdominal main bifurcation stent graft, extension stent graft and branch stent graft. The abdominal main body of inner embedded stent graft is composed of abdominal main embedded covered stent and conveyor, the abdominal main bifurcated stent graft is composed of abdominal main bifurcated stent and conveyor, the extended stent is composed of extended stent graft and conveyor, and the branch vascular stent graft is composed of branch vascular stent and conveyor. The abdominal main body of inner embedded stent graft, abdominal main bifurcation stent graft, extension stent graft and branch vascular stent graft are pre-installed in the corresponding conveyor respectively.
Study NCT04794426 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Silver diamine fluoride
Description: Previous studies have recommended that Silver diamine fluoride (SDF) solution would exert a preventive result in managing early childhood caries ECC. However, no well-designed clinical trials have yet been performed to study the effect of SDF on caries prevention. the objective is useful in arresting early childhood caries (ECC)
Study NCT04794426 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hall Technique
Description: The first report on the Hall Technique published in 2007 by a general dental practitioner from Aberdeen/Scotland, Dr. Norna Hall. Dr. Hall used PMCs to restore carious primary molars rather than using the standard technique, placed them using a simplified method.
Study NCT06171230 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing
Description: Using the LEC and PCL-5, emotionally charged images are selected at the onset of the EMDR intervention. Initially, events meeting the criteria for PTSD (A-criterion worthy events) are processed. Subsequently, pain-related experiences, including any distressing images, are addressed. If the emotional charge of the events diminishes (SUD=0) before the completion of the six EMDR sessions, the participant is categorized as an 'early completer,' and the post-assessment is conducted immediately. The duration of each EMDR session is 90 minutes.
Study NCT06171230 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Attention control phase
Description: Prior to EMDR, there is a two-week attention control phase. During this phase, the participant is asked to daily record their activities, emotions, and thoughts when experiencing pain. This information is further explored and evaluated in two sessions lasting 45 minutes each, involving in-depth discussions with the participant.
Study NCT06513013 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neostigmine
Description: 25ml volume on each side (20ml of 0.25% bupivacaine plus 5ml of normal saline containing 500 mcg neostigmine.~A 22-gauge spinal needle will be advanced using the in-plane technique at the anterior axillary line, and the precise position of the needle tip between the internal oblique and transverse abdominis muscle will be visualized. To expand the plane, 2 mL of normal saline will be administered. Following the affirmation of a hypoechoic region on the USG image, the study solutions will be injected as per group allocation. Postoperatively,both groups of patients received an injection of paracetamol 1gm intravenously every 8th hourly as a part of multimodal analgesia and the patients will be evaluated for pain, nausea or vomiting in the post anaesthesia care unit at time 0 (time of completion of TAP block), 2, 4, 6,12 and 24 h by an investigator blinded to the group assignment. Whenever the NRS >4, Nalbuphine 0.1 mg/kg IV will be administered as a rescue analgesic.
Study NCT05454215 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical insufflation/exsufflation conventional
Description: Conventional settings in a commercially available chest physiotherapy device
Study NCT05454215 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical insufflation/exsufflation conventional
Description: Conventional settings in a commercially available chest physiotherapy device
Study NCT05454215 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical insufflation/exsufflation modified
Description: Modified settings in a commercially available chest physiotherapy device
Study NCT05454215 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical insufflation/exsufflation modified
Description: Modified settings in a commercially available chest physiotherapy device
Study NCT06483607 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: M-TAPA block with bupivacaine 25%
Description: Following sterile conditions for bilateral M-TAPA block application, the transducer will be inserted on the chondrium in the sagittal plane at the 9-10th rib level. Subsequently, a deep angle will be created with the probe for visualization of the underside of the costochondrium. The sonovisible needle tip will be placed just below the chondrium and saline (5 ml) will be injected for site confirmation. After the confirmation, 20 ml of 0.25% bupivacaine will be administered for each group for a total of 40 ml of local anesthetic. Blocks will be applied using an 80 mm sonovisible needle with a 6-10 MHz linear probe under the guidance of a portable ultrasound. M-TAPA block with the same standard technique and drug dose will be applied to the contralateral side for each group of M-TAPA patients.
Study NCT06483607 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TAP block with bupivacaine 25%
Description: After the necessary sterilization conditions established, the linear ultrasound probe will be placed in the middle of the iliac crest with the end limit of the ribs. Starting with skin, the layers in descending order, subcutaneous adipose tissue, external oblique muscle, internal oblique muscle, transversus abdominis muscle, and peritoneum will be identified. As the tip of the 80 mm sonovisible needle passes through the muscular layers and fascia, the needle will be advanced in a controlled manner. After receiving the click sensation (passage of the fascia of the internal oblique muscle), the location of the needle will be fixed and 20 ml of 0.25% bupivacaine will be injected between internal oblique and transversus abdominis muscles. Same procedure will be performed to the other site. (40 ml local anesthetics in total)
Study NCT04976959 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High Fiber supplement
Description: The supplement consists of a mixture of soluble fibers (from inulin and fibersol-2) and insoluble fibers (from oat bran, corn bran, wheat bran and sorghum bran) and it will be consumed as a drink.
Study NCT04828564 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ribavirin Capsules
Description: Ribavirin 200 mg capsules
Study NCT04828564 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Favipiravir
Description: Favipiravir 200 mg tablets
Study NCT05861362 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Curative radiotherapy
Description: Curative radiotherapy as indicated by the patient's disease and prescribed by the treating radiation oncologist
Study NCT05861362 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5:2 intermittent fasting
Description: Two nonconsecutive days of fasting per week that could be chosen freely according to the patient's weekly schedule.
Study NCT05796648 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RN-CHeFRx
Description: The RN-CHeFRx trial to enhance dietary intake and blood pressure control in Black women with hypertension and obesity compared to usual care.
Study NCT03625986 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine-Containing Electronic Cigarette
Description: The electronic cigarette (e-cig) used in this study will be the Standardized Research Electronic Cigarette (SREC). The SREC product is a pod-based device and comprises a replaceable pre-filled liquid reservoir (pod) and a rechargeable power supply unit. The experimental group in this project will receive a SREC device with liquid containing 58 mg/mL of nicotine.
Study NCT03625986 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Non-Nicotine Electronic Cigarette
Description: The electronic cigarette (e-cig) used in this study will be the Standardized Research Electronic Cigarette (SREC). The SREC product is a pod-based device and comprises a replaceable pre-filled liquid reservoir (pod) and a rechargeable power supply unit. The placebo group in this project will receive a SREC device with liquid containing 0 mg/mL of nicotine.
Study NCT04881227 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Chatbot on COVID-19 vaccine hesitancy
Description: This intervention will provide to participants information on COVID-19 vaccine hesitancy consisting of the possibility of accessing a long series of questions and answers online about this vaccination.
Study NCT04881227 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control intervention
Description: This control intervention will provide to participants a brief text decribing the way vaccines works.
Study NCT06114212 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dTMS stimulation via the H4 coil
Description: Deep repetitive transcranial magnetic stimulation (dTMS) uses transient electromagnetic fields to stimulate the brain and is approved by Health Canada and the FDA for the treatment of depression, anxious depression, obsessive-compulsive disorder, and tobacco use disorder. Compared to the traditional TMS, dTMS is able to target brain depths ranging from 2 to 6 cm. With the use of various H-coils, dTMS has been used to target specific neural networks with the aim of producing desired clinical effects in psychiatric populations. The intervention in this study is the H4 dTMS coil which stimulates the lateral prefrontal cortex and the insula in the brain.
Study NCT05747963 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: software-delivered CBT-I
Description: The automated software called 'resleep' incorporates all core elements of CBT-I: sleep restriction, stimulus control, cognitive therapy, relaxation techniques, and sleep hygiene and education, tailoring content based on each participant's reported baseline sleep function and sleep progress. The 6-week treatment includes 42 times of intervention.
Study NCT06288841 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ropivacaine injection
Description: Ultrasound-guided bilateral QLB2 was performed using Ropivacaine injection prior to anesthesia induction
Study NCT06288841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine liposome
Description: Ultrasound-guided bilateral QLB2 was performed using Bupivacaine liposome injection prior to anesthesia induction
Study NCT05747963 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: online PE
Description: Subjects in the control group will receive non-tailored information about insomnia and sleep health education content using the Wechat Official Account.
Study NCT05510128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist management
Description: When a patient comes to the pharmacy with signs of urinary burning, the following will follow:~* Completion of the acute cystitis symptoms score (ACSS) questionnaire.~* Measure the temperature.~* Perform a urine dipstick.~If the patient's temperature is normal, the urine dipstick is positive, and the absence of pain in the lumbar fossa is verified, the pharmacist can dispense an appropriate antibiotic himself. A reminder of the hygienic-dietary rules is also issued, and a communication to the patient's general practitioner will be made.
Study NCT05041153 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Given by PO
Study NCT05041153 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given by IV
Study NCT06160895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ-A3334 tablets
Description: TQ-A3334 tablet is a Toll like receptor 7 (TLR7) agonist.
Study NCT06160895 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: TQ-A3334 placebo tablets
Description: TQ-A3334 placebo tablet is a placebo that has no effect on TLR7.
Study NCT04927130 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ARNA Breast
Description: A specific DNA fragments and globulins will be detected in blood plasma.
Study NCT05520463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sacral lateral branch radiofrequency ablation under ultrasound guidance
Description: Sacral lateral branch radiofrequency ablation will be performed under ultrasound guided approach.
Study NCT05520463 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacral lateral branch radiofrequency ablation under fluoroscopy guidance
Description: Sacral lateral branch radiofrequency ablation will be performed under fluoroscopy guided approach.
Study NCT05112809 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cochlear Stimulation System (CSS)
Description: Cochlear stimulation with surround sound and noise cancellation
Study NCT04964999 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will undergo an exercise program during the 2-week bed rest period.
Study NCT05156372 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training
Description: Participants will perform high-intensity aerobic and resistance exercise
Study NCT04777786 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Therapy
Description: Individualized physical therapy treatments will be provided based on impairments identified during assessments. Treatment may include but is not limited to the following: passive, assisted and active ROM, manual therapy, soft tissue massage, myofascial release, therapeutic activities and exercise and patient education. Treatment duration and frequency will be specific to each patient, providing personalized care. This type of intervention is considered a pragmatic approach, which will allow for generalization of the results due to the similarity with clinical practice.71 Pilot data indicates women will receive physical therapy intervention 1-2x/week for 3-6 weeks beginning \~4 weeks after surgery (x̄=10 visits).
Study NCT06214286 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Shockwave
Description: Shockwave therapy
Study NCT06214286 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Kinesio taping application
Study NCT06214286 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio taping
Description: Kinesio taping application
Study NCT06214286 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physical therapy
Description: conventional physical therapy
Study NCT06214286 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional physical therapy
Description: conventional physical therapy
Study NCT05777967 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: human autologous synovial stem cells
Description: A single injection of 1.5 to 9.0 x 10\^7 human autologous synovial stem cells under arthroscopy
Study NCT05767229 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carvedilol
Description: Carvedilol 0.2 mg/kg for 1.5 hrs
Study NCT06158204 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle Intervention
Description: Participants will receive guidance on when and what to eat and when to sleep and be physically active. Additionally, participants will be provided with whey protein isolate powder to be mixed with water and grain-based snack bars to be consumed primarily during work shifts. Lean body mass (kg) will be used to prescribe total caloric (\~30kcal/kg lean mass) and protein (2g/kg lean mass) needs and sleep/rest goals will be 6-8 hours per 24 hour day
Study NCT06158204 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Intervention
Description: Participants will receive guidance on when and what to eat and when to sleep and be physically active. Additionally, participants will be provided with whey protein isolate powder to be mixed with water and grain-based snack bars to be consumed primarily during work shifts. Lean body mass (kg) will be used to prescribe total caloric (\~30kcal/kg lean mass) and protein (2g/kg lean mass) needs and sleep/rest goals will be 6-8 hours per 24 hour day