AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05075551 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Hwato brand disposable acupuncture needles (size 0.30 × 75mm; size 0.30 × 40mm) will be used.SP6 is on the tibial aspect of the leg, posterior to the medial border of the tibia, 3 cun superior to the prominence of the medial malleolus; BL23 is in the sacral region, in the second posterior sacral foramen; BL54 is in the fourth posterior sacral foramen, 3 cun beside the median sacral crest; BL35 is in the buttock region, 0.5 cun lateral to the extremity of the coccyx.
Study NCT05075551 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture
Description: Hwato brand disposable acupuncture needles (size 0.30 × 75mm; size 0.30 × 40mm) will be used.These volunteers will receive relatively shallow needling at bilateral sham SP6, BL54, BL23 and BL35. This treatment gets involved in the same duration and frequency of sessions, but the treatment was delivered superficially at non-acupuncture points 10 mm to the lateral of corresponding acupuncture and not above a meridian line (10mm to SP6, BL54, BL23 and BL35).The same equipment of fMRI scanner will be used.
Study NCT05075551 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fMRI scan
Description: Both two group will get fMRI scan week 0 (before treatment), week 12 (after treatment) and week 36 (following up). The resting-state fMRI data will be obtained by using a 3.0T GE MR 750 MRI scanner with an eight-channel phase array head coil at the Huashan Hospital, Shanghai. The high resolution T1-weighted magnetic resonance images will be collected by a three-dimensional fast spoiled gradient-echo dual-echo sequence \[repetition time (TR) = 8100 ms; echo time (TE) = 3.1 ms; FA = 8 deg; matrix=256 × 256; field of view (FOV)=25.6× 25.6 cm2; slice thickness=1 mm; no gap and 156 slices\]. The whole resting state fMRI data will be acquired by using a gradient-recalled echo-planar imaging pulse sequence (TR/TE = 2,000/30 ms; FA = 90°; acquisition matrix = 64×64; FOV = 22×22 cm2; slice thickness= 4 mm; 43 slices and total 240 time points; no gap).
Study NCT05075551 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: fMRI scan
Description: Both two group will get fMRI scan week 0 (before treatment), week 12 (after treatment) and week 36 (following up). The resting-state fMRI data will be obtained by using a 3.0T GE MR 750 MRI scanner with an eight-channel phase array head coil at the Huashan Hospital, Shanghai. The high resolution T1-weighted magnetic resonance images will be collected by a three-dimensional fast spoiled gradient-echo dual-echo sequence \[repetition time (TR) = 8100 ms; echo time (TE) = 3.1 ms; FA = 8 deg; matrix=256 × 256; field of view (FOV)=25.6× 25.6 cm2; slice thickness=1 mm; no gap and 156 slices\]. The whole resting state fMRI data will be acquired by using a gradient-recalled echo-planar imaging pulse sequence (TR/TE = 2,000/30 ms; FA = 90°; acquisition matrix = 64×64; FOV = 22×22 cm2; slice thickness= 4 mm; 43 slices and total 240 time points; no gap).
Study NCT04895046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: 300 mg taken orally (all cycles)
Study NCT04895046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: 500 mg (cycles 1-4) intravenously
Study NCT04895046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: 1000 mg (cycle 5+) intravenously
Study NCT04983589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pilocarpine HCl
Description: Pilocarpine HCl ophthalmic solution 1.25% ocular drops.
Study NCT04983589 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Oxymetazoline HCl and pilocarpine HCl placebo ocular drops.
Study NCT05635682 — intervention group
Intervention type: OTHER
Intervention: Observational and anthropometric assesments
Description: Plantar sensation, foot reaction time, head and trunk proprioceptions, posture, balance and gait assesments
Study NCT04699656 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Plazomicin Injection
Description: single dose of plazomicin
Study NCT05100615 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: surgery
Description: applying the graft inside bony defect after surgery
Study NCT05455476 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT for Loneliness
Description: CBT delivered over the course of 8, \~45 minute sessions delivered via telehealth more centrally focused addressing factors contributing to loneliness and social isolation.
Study NCT05455476 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CBT for Chronic Pain
Description: CBT delivered over the course of 8, \~45 minute sessions delivered via telehealth broadly focused on increasing quality of life despite being in pain.
Study NCT04972318 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ARDSNet ventilatory strategy
Description: Positive end-expiratory pressure will be set according to fixed inspired oxygen fraction values.
Study NCT05859594 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laughter yoga
Description: Although the history of laughter yoga dates back to ancient times, its use in medicine has become widespread in the 21st century, while it is used to reduce pain, anxiety, stress, depression and fatigue, it is also a method that can be used to accelerate immunity, quality of life, happiness, sleep quality and recovery.
Study NCT06411873 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control Group
Description: Composition of formula per 100 mL : energy (100 kcal), protein (3 g), carbohydrate (13.54 g), lipids (3.93 g), protein energy ratio/PER 12%, osmolarity (310 mOsm/L), renal solute load/RSL (27.5 mOsm/100 kcal)
Study NCT06411873 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Intervention Group
Description: Composition of formula per 100 mL : energy (105.5 kcal), protein (4.35 g), carbohydrate (13.54 g), lipids (3.93 g), protein energy ratio/PER 16.5%, osmolarity (333.5 mOsm/L), renal solute load/RSL (27.7 mOsm/100 kcal)
Study NCT06418594 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Adebrelimab: 1200mg, ivgtt, administered on the first day of each cycle, with a cycle of 21 days
Study NCT06418594 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apatinib
Description: Apatinib: 250 mg, oral, once daily, continuous use, with a cycle of 21 days
Study NCT06418594 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Etoposide: 50mg/day, oral, administered on days 1-14 of each cycle, with a cycle of 21 days
Study NCT06360393 — intervention group
Intervention type: DEVICE
Intervention: Smart spacer
Description: Participants' inhalation medication adherence and inhalation technique will be monitored using a smart spacer. Their usual medication regime will be continued and they will not receive information about their adherence or inhalation technique measured by the spacer during the follow-up year (except for any interventions that will be done in standard care).
Study NCT04947696 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sampling
Description: Blood sampling preoperatively and sequentially up to 30 days post op
Study NCT05548946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: PID-5-BF+M and LPFS-BF 2.0 (self-report questionnaires)
Description: All participants will be asked to fill in the PID-5-BF+M and the LPFS-BF 2.0 to examine personality disorders as defined by the AMPD and ICD-11.~PID-5-BF+M consists of 36 self-report items. It has 18 facet scales and 6 domain scales (Anankastia, Negative Affectivity, Antagonism, Disinhibition, Psychoticism and Detachment).~The LPFS-BF 2.0 has 12 items, measuring 4 domains of personality functioning (identity, intimacy, self-direction and empathy).
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive
Description: Tree 10 minutes individual sessions per week involving memory, attention and executive functions tasks.
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobility
Description: Two 30 minutes group session per week involving physical activity assisted by a social robot.
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Social
Description: One 60 minutes group session per month assisted by a social robot that facilitates talking about costumes and traditions.
Study NCT05548946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Secondary Questionnaires (self-report and informant questionnaires)
Description: The patients fill in a standard test battery during the first weeks of their admission in the institutions, including questionnaires and interviews. The research team will analyze the results retrospectively.~This includes:~YSQ- SF16 (Young \& Brown, 1994; Pauwels et al., 2018) GPS (van Alphen et al., 2006) HoNOS 65+ (Burns et al., 1999) HAP 2.0 (Barendse \& Thissen, 2006) SCL-90-R (Derogatis, 1983; Dutch version: Arrindell, \& Ettema, 1975, 1986, 2005) ADP-IV (Schotte \& De Doncker, 1998) CERQ (Garnefski et al., 2007) UCL (Scheurs et al., 1994; 1988) BIS/BAS Scales (Carver \& White, 1994) EC Scale of the ATQ (Rothbart et al., 2000) BSI (Derogatis, 1975; Dutch version: Beurs, 2008) SIPP-SF (derived from the SIPP-118; Verheul et al., 2008) SMI (Young et al., 2008) WHO-5 (Dutch version: WHO, 1998) SQ3-SF (Young \& Brown, 2005) SCID-5-P (First et al., 2017; Dutch translation: Arntz et al., 2017)
Study NCT05548946 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Clinical Ratings of the dimensional model
Description: Clinical ratings of criteria A and B will also be collected. Only a small part of the patients will be selected for this, in order to make the research more feasible. The rater (a clinician or researcher) assesses the patient (in terms of level of personality functioning and personality traits) by means of (structured) clinical interviews. Given clinical ratings of the dimensional criteria are not part of the standard care in either institution, the ratings can be conducted by the doctorandus and Master Thesis students, trained by the doctorandus (in order not to overburden the clinicians).~The clinical interviews that will be used for the ratings are:~* The Semigestructureerd Interview voor Persoonlijkheidsfunctioneren DSM-5 (STIP) (Hutsebaut et al., 2014).~* The Structured Clinical Interview for the DSM-5 (SCID-5-AMPD) (First et al., 2018), only if a Dutch translation is available by the time of this intervention.
Study NCT05548946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: PID-5-BF+M and LPFS-BF 2.0 (Informant questionnaires)
Description: In the clinical population, participants will be asked to include an informant (family member, partner, friend, acquaintance), to fill in an informant version of the PID-5-BF+M and LPFS-BF 2.0 questionnaires. It is also possible for the patient to participate in the study without giving permission to include an informant. The informant will be asked to fill in the informant versions of the questionnaires, which contain the exact same items as the self-report versions, adjusted to the third person.
Study NCT06703567 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Policy
Description: Patients will receive information about the GEP test by clinical teams
Study NCT06703567 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Policy + GEP Information Film
Description: Patients will receive information about the GEP test by clinical teams and, after consultation with physician, they will be sent a link to view the film regarding OncotypeDX
Study NCT06725472 — intervention group
Intervention type: PROCEDURE
Intervention: Open Heart Surgery
Description: This is a general term for surgical procedures that directly access the heart through an opening in the chest to treat heart problems.
Study NCT06725836 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implantation of electrodes into the epidural space for spinal cord stimulation
Description: Under X-ray guidance and with neurophysiological supervision, the electrode is implanted. The stimulator is surgically placed in a pocket formed in the iliac crest area on the left side, where it is secured. The generator is connected to an electrode array positioned on the dorsal epidural surface of the spinal cord at the appropriate level (sacral-lumbar/cervical region), as confirmed by intraoperative fluoroscopy.
Study NCT06725836 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Selection of the optimal spinal cord stimulation program for spastic syndrome suppression
Description: During the selection of the optimal stimulation program for spasticity suppression, spinal cord stimulation (SCS) is performed at various sites on the electrode array. Stimulation is initiated at a specific site with a frequency of 60 Hz, and the intensity is gradually increased until the spasticity is alleviated (i.e., the limb can flex and extend without restriction). If there is no effect, the stimulation frequency is increased by 5 Hz, and the intensity is again adjusted from 0 to comfortable values. Stimulation is sequentially applied at different sites, and those sites where muscle spasticity is most effectively suppressed are selected.
Study NCT06725836 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Selection of the optimal spinal cord stimulation program for volitional motor control
Description: Over the course of two weeks, the configuration of the electrodes and the intensity of the stimulation are adjusted to ensure optimal voluntary muscle control. A systematic approach is used to determine the most suitable settings. First, the anodes and cathodes on the electrode array are identified. The desired frequency range is 20-40 Hz. The pulse width is determined empirically. The adjustment begins at 20 Hz, with the stimulation intensity gradually increased. If unpleasant sensations (such as muscle spasms or pain) occur, the intensity is reduced to comfortable values. If there is no effect, the stimulation frequency is increased by 5 Hz, and the intensity is adjusted again from 0 to comfortable levels. Stimulation is sequentially applied at different sites, with the sites that provide the most effective voluntary muscle control being selected.
Study NCT06725836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Resting electroencephalography for identifying neurocorrelates of spinal cord stimulation.
Description: The procedure utilizes the method of electroencephalography (EEG). Throughout the procedure, EEG signals are recorded. Initially, the participant is recorded in a resting state before the implantation of the stimulator for 20 minutes (5 minutes with eyes open, followed by 5 minutes with eyes closed). After the surgery, the participant is recorded in the same manner before the first activation of the stimulator. After selecting the programs, the participant is recorded without stimulation (eyes open, then closed), followed by recordings with the spinal cord stimulator (SCS) activated (eyes open, then closed). The stimulation is then turned off again, and recording is conducted with eyes open and closed. Before discharge, the participant is recorded in a resting state for 20 minutes with the stimulation program active.
Study NCT06725836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Electroencephalography within the motor imagery paradigm
Description: The procedure utilizes the method of electroencephalography (EEG). Throughout the procedure, EEG signals are recorded. During the experiment, with the stimulator turned off, the participant views a fixation cross on a computer screen. Then, they hear an auditory signal and see a sign indicating a specific movement (complete flexion and extension of the left arm, complete flexion and extension of the right arm, complete flexion and extension of the left leg, complete flexion and extension of the right leg). The participant imagines the movements according to the auditory and visual signals on the screen. Subsequently, the participant performs the same movements in the same order. The motor control stimulation program is then activated, and the entire sequence is repeated (first imagining the movement, then performing the imagined movements). The timing of the command presentations is recorded with marker placements.
Study NCT06725654 — intervention group
Intervention type: OTHER
Intervention: Diagnostic Procedures
Description: To evaluation the oral and dental health of orphaned children, DMFT, deft, GI, PI and CPITN indices were used to assess dental caries experience, gingival inflammation, the amount of plaque on the tooth surface and periodontal status, respectively.
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Relational
Description: Unrestricted individual interaction of the user with the Pepper robot to obtain information of interest for the user (menu, time, date, place and calendar of activities of the residential. center) and 1 individual monthly videoconference with the family of 10 minutes of duration.
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Attentions and treatments received by the persons before the enrollment in the study.
Study NCT06344676 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Attentions and treatments received by the persons before the enrollment in the study.
Study NCT05976880 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment of isometric hand grip training exercises
Description: In control group, conventional treatment perform by using isometric hand grip training exercises (putty grip and squeeze exercise, thumb pinch z strengthening exercises, isometric Hooks exercises, rubber band abduction and c thumb exercises) for 3times a week in one month.
Study NCT06032026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 11C-HY-2-15 PET
Description: 2 hour Positron Emission Tomography (PET) scan using new radiotracer 11C-HY-2-15
Study NCT06032026 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: brain MRI
Description: brain MRI scan
Study NCT06032026 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Amyloid PET scan
Description: PET scan with Florbetaben F18 or 11C-PiB
Study NCT06032026 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neurological assessments
Description: Neurological assessments, including video interview
Study NCT05953610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide 500 MG QHS
Description: Acetazolamide
Study NCT05953610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eszopiclone 3 mg QHS
Description: Eszopiclone
Study NCT04766658 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Gargle Phonation
Description: Subjects will gargle water while making sound
Study NCT04766658 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Water swallow
Description: Subjects will hold water in their mouth for 5 seconds and swallow
Study NCT04494334 — intervention group
Intervention type: PROCEDURE
Intervention: Bronchoscopy for Probable Idiopathic Pulmonary Fibrosis and Sarcoidosis
Description: Blood samples and Nasosorption sampling
Study NCT05765318 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: QLB
Description: QLB is ultrasound-guided injection of 30 ml bupivacaine 0.25% into quadratus lumborum plane posterior to the end of internal oblique muscle.
Study NCT05458791 — intervention group
Intervention type: DEVICE
Intervention: Intra-arterial Perfusion
Description: All patients will undergo standard of care locoregional intra-arterial (IA) treatment for HCC. The procedure will take place utilizing fluoroscopic and CT guidance. Following catheterization of the femoral or radial artery, CT angiography of the hepatic circulation will be performed to define the hepatic vascular anatomy. Intra-arterial CT perfusion will be performed prior to IA treatment by the interventional radiologist to understand the dynamics of hepatic circulation or to manage the IA treatment strategy.
Study NCT04940091 — intervention group
Intervention type: DRUG
Intervention: Epidural analgesia
Description: Epidural analgesia is performed with a mixture of local anesthetics (ropivacaine) and opioids (sufentanil).
Study NCT05375110 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NoYA™ Radiofrequency Interatrial Shunt System
Description: NoYA™ Radiofrequency Interatrial Shunt System include Adjustable Interatrial Shunt System and Radiofrequency Ablation Generator.
Study NCT04800510 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Carbon Fiber Custom Dynamic Orthosis (CDO)
Description: The CDO will consist of a semi-rigid foot plate, a posterior carbon fiber strut, and a proximal cuff below the knee.
Study NCT04748549 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality Immersive Relaxation
Description: The VR software developed allows patients to select from scenery such as mountains, the beach or from a selection of short videos, which are intended to promote relaxation.
Study NCT04748549 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Immersive Audio Experience
Description: A study team member will play from a library of music or other audible content (audiobook, podcast) that was preselected by the patient.
Study NCT04748549 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Virtual Reality Experience
Description: Subjects will wear VR headsets and headphones but will not view any content or listen to any audible content.
Study NCT05543226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PHGG-rich enteral nutrtiion
Description: PHGG-rich enteral nutrition
Study NCT05217758 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mifepristone
Description: 1200 mg/day, once daily, 7 days
Study NCT05217758 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, once daily, 7 days