AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06443151 — intervention group
Intervention type: DRUG
Intervention: Acetylcholine
Description: Endothelium-dependent vasodilation will then be assessed by changes in FBF in response to intra-arterial infusions of the endothelial agonist acetylcholine infused at rates of 4.0, 8.0, 16.0 μg/100 mL of forearm tissue/min to generate a dose-response curve.
Study NCT06443151 — intervention group
Intervention type: DRUG
Intervention: Sodium Nitroprusside
Description: Endothelium-independent vasodilation will be assessed by changes in forearm blood flow in response to intra-arterial infusions of sodium nitroprusside at 1.0, 2.0, 4.0 μg/100 mL forearm tissue/min.
Study NCT06443151 — intervention group
Intervention type: DRUG
Intervention: Ascorbic acid
Description: Ascorbic acid will be infused at a constant rate (12 mg/100 mL tissue/min) and maintained at the same rate while the acetylcholine and sodium nitroprusside dose-response curves are repeated.
Study NCT06443151 — intervention group
Intervention type: PROCEDURE
Intervention: venous phlebotomy
Description: Venous blood samples will be collected to measure baseline cardiometabolic characteristics and isolate endothelial cell microvesicles for characterizations and in vitro experiments.
Study NCT05832658 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: With EMG-Biofeedback
Description: Once a day for a total of 15 sessions, the Mendelsohn maneuver will be performed for 15 minutes and the effortful swallow maneuver will be performed for 15 minutes with game-based emg-biofeedback.
Study NCT05832658 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Without EMG-Biofeedback
Description: Once a day for a total of 15 sessions, the Mendelsohn maneuver will be performed for 15 minutes and the effortful swallow maneuver will be performed for 15 minutes with only verbal feedback.
Study NCT05832658 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Patient and family education will be provided by the investigator. In addition, each patient will be evaluated and oral motor exercises and thermal tactile stimulation will be given to each patient when necessary.
Study NCT05832658 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Patient and family education will be provided by the investigator. In addition, each patient will be evaluated and oral motor exercises and thermal tactile stimulation will be given to each patient when necessary.
Study NCT03734484 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: InSight
Description: The InSight algorithm which draws information from a patient's electronic health record (EHR) to predict the onset of severe sepsis, and in this study will be customized to differentiate between various Gram-type infections.
Study NCT05916287 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood and urine samples
Description: Blood and urine samples
Study NCT05916287 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Blood samples
Description: Blood samples
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cardiovascular assessment
Description: Echocardiography, Lung ultrasound, pulse wave velocity, carotid stiffness and thickness, Central and peripheral blood pressure, carotid pulse pressure, abdominal aorta ultrasound, jugular vein ultrasound, liver elastography (Optional).
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietary intake
Description: Food frequency questionnaires, ''Dutch eating behaviour questionnaire'' and dietary supplement questionnaire
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anthropometric parameters
Description: Measurement of height, weight, abdominal circumference, hip circumference, arm circumference
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodynamic parameters
Description: Systolic pressure index measurement
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodynamic parameters
Description: Heart rate measurements, blood pressure measurements, orthostatic BP measurements
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodynamic parameters
Description: Blood pressure measurements by unattended BP monitor over 5 min
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hemodynamic parameters
Description: Electrocardiogram
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxneuvance
Description: The Vaxneuvance (15-valent pneumococcal conjugate vaccine) co-administered intramuscularly. In some countries PCV will only be administered depending on the availability, country's registration status and national recommendations for pneumococcal vaccination at the time of study conduct.
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Assessment of compliance with antihypertensive treatments for treated participants
Description: EVALOBS scale and compliance questionnaire
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ambulatory 24 hours measurment of blood pressure
Description: For the first 100 patients willing to participate
Study NCT05491187 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.5% bupivacaine heavy
Description: Spinal anesthesia with 0.5% bupivacaine heavy at L3-L4 intervertebral space using Quincke's spinal needle in sitting position, single administration for each patient
Study NCT05491187 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.5% bupivacaine heavy with fentanyl
Description: Spinal anesthesia with 0.5% bupivacaine heavy with fentanyl at L3-L4 intervertebral space using Quincke's spinal needle in sitting position, single administration for each patient
Study NCT06352138 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Experimental: Epoetin alfa Megalabs® Erythropoietin injectable in intravenous administration.
Description: comparison vs the reference product to demonstrate biological similarity
Study NCT06352138 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Active comparator: European Union licenced epoetin alfa
Description: comparison vs. the test product to demonstrate biological similarity
Study NCT06555458 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Patient group to be given dexmedetomidine
Study NCT06555458 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Patient group to be given salin
Study NCT05916287 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 24 hours urinary collection
Description: For the first 100 patients willing to participate. For biobank constitution and measurement of microalbuminuria, creatininuria, osmolarity, natriuresis, kaliuresis, urea, proteinuria and urine dipstick
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: General questionnaires
Description: Collection of socio-demographic data such as age, level of education, profession, household income, smoking status, physical activity, perception of health, prematurity, height and weight at birth, family and personal history especially cardiovascular (history of stroke, myocardial infarction, heart failure, current pathologies, drugs, tobacco...)
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Women specific questionnaire
Description: Women specific questionnaire
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Women specific questionnaire
Description: Women specific questionnaire
Study NCT05916287 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NYHA dyspnea questionnaire
Description: Determination of NYHA class.
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Anxiety questionnaire
Description: Assessment of anxiety
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Epworth Sleepiness Scale
Description: sleep quality assessment
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A questionnaire on the perception of the management of cardiovascular risk factors
Description: Patient's evaluation of cardiovascular risk factors by the health system
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A questionnaire on eating behaviors
Description: Assessment of eating behaviors
Study NCT05916287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A questionnaire on eating habits to determine consumer profiles
Description: Assessement of eating habit to create a consumer profile
Study NCT05916287 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: A questionnaire on food supplements use
Description: Evaluation od food supplements intake
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 Infection Questionnaire
Description: SARS-CoV-2 Infection Questionnaire
Study NCT05916287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instantaneous expired air analysis
Description: Carbon monoxyde analysis in expired air
Study NCT05916287 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Capillary sampling
Description: Capillary sampling for pollutant analysis (Optional)
Study NCT05391087 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mean arterial pressure based management
Description: Mean arterial pressure group: Low MAP will be intervened in accordance with the protocol as described in the arm
Study NCT05391087 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cardiac index based management
Description: Cardiac index group: Low CI will be intervened in accordance with the protocol as described in the arm. Additionally, if MAP is lower than target MAP along with a normal CI, this will be intervened with noradrenalin infusion/titration
Study NCT06567340 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: StratCare
Description: The StratCare app is a technology that collects data, processes inputs using a machine learning algorithm, and outputs a personalised treatment recommendation using automated decision rules. The inputs for the algorithm include patient-reported measures of depression, anxiety, functional impairment, personality traits, employment status and ethnic background. The algorithm calculates an expected prognosis (i.e., a probability of full remission of depression and anxiety symptoms after treatment), based on which patients are classified as standard (better expected prognosis) or complex cases. Standard cases are matched to low-intensity treatments and later have the option to move to high-intensity, whereas complex cases are matched directly to high-intensity treatments. In addition, the StratCare app is programmed to implement decision rules that ensure compliance with national clinical guidelines for the treatment allocation of patients with specific disorders.
Study NCT04861038 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: aerSleep II
Description: Continuous negative external pressure (cNEP) system that maintains an open airway by applying negative pressure to the anterior neck via a soft silicone collar
Study NCT06370247 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: HbA1c, serum creatinine, eGFR urine analysis and serum electrolyte Na and K
Description: HbA1c, serum creatinine, eGFR urine analysis and serum electrolyte Na and K will measure
Study NCT05852392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adapted PARENT Model
Description: PARENT is a team-based approach to care that utilizes a clinic-based community health worker as part of the WCC team to provide comprehensive and family-centered preventive care services.
Study NCT06455137 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epidural Stimulator
Description: Participants will have a 16-electrode epidural array implanted in the C4-C7 and T11-L2 areas of the spinal cord. Following a 2 weeks recovery period, patients will engage in a structured training of physical rehabilitation and electrical stimulation.
Study NCT05487625 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-ventilated cigarette alone
Description: High-ventilated cigarettes are the only available cigarettes in the Experimental Tobacco Marketplace which increases in price across trials. Other nicotine/tobacco products are available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.
Study NCT05487625 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low-ventilated cigarette alone
Description: Low-ventilated cigarettes are the only available cigarettes in the Experimental Tobacco Marketplace which increases in price across trials. Other nicotine/tobacco products are available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.
Study NCT05487625 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High- and low-ventilated cigarette with high-ventilated cigarettes increasing in price
Description: High- and low ventilated cigarettes are available in the Experimental Tobacco Marketplace with high-ventilated cigarettes increasing in price across trials. Other nicotine/tobacco products are available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.
Study NCT05487625 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low- and high-ventilated cigarette with high-ventilated cigarettes increasing in price
Description: Low- and high-ventilated cigarettes are available in the Experimental Tobacco Marketplace with low-ventilated cigarettes increasing in price across trials. Other nicotine/tobacco products are available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.
Study NCT05487625 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual, high- and low-ventilated cigarette with usual cigarettes increasing in price.
Description: Usual cigarette, low- and high-ventilated cigarettes are available in the Experimental Tobacco Marketplace with usual cigarettes increasing in price across trials. Other nicotine/tobacco products are available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.
Study NCT06095401 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inelastic adjustable compression garment (INCOM)
Description: Immediately following surgery, participants randomized to INCOM will wear an inelastic adjustable compression garment set to a minimum of 30mm Hg of compression utilizing a standardized garment tensioning tool. Participants will be instructed to wear the compression garment during waking hours with a target wear time of 80% of waking hours. Participants will participate in a standardized rehabilitation program
Study NCT06095401 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Elastic compression garment (CONTROL)
Description: Immediately following surgery, participants randomized to CONTROL will wear a thigh-length elastic compression garment (thromboembolism-deterrent \[TED\] hose) for the first 3 weeks after TKA. Participants will be instructed to wear the compression garment during waking hours with a target wear time of 80% of waking hours. Participants will participate in a standardized rehabilitation program
Study NCT06274437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BND-35
Description: Pharmaceutical form: Solution for infusion; Route of administration: Intravenous
Study NCT06274437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Pharmaceutical form: Solution for infusion; Route of administration: Intravenous
Study NCT06274437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Pharmaceutical form: Solution for infusion; Route of administration: Intravenous
Study NCT05029362 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: SmokefreeSGM
Description: Participants will have access to a text-based smoking cessation program tailored to sexual minority individuals (SmokefreeSGM). The text-based program will be beta-tested by these participants for a period of 2 weeks before and 10 weeks after their quit date. Messages originated from the text-based smoking cessation program will be sent by a fictitious quit coach who will offer evidence-based advice on quitting smoking based on real-life experiences of sexual minority individuals.
Study NCT05514899 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: THC
Description: THC capsule
Study NCT05514899 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC
Description: THC capsule
Study NCT05514899 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CBD
Description: oral solution
Study NCT05514899 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD
Description: oral solution
Study NCT05507684 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nature-based social prescribing group intervention
Description: Groups of 5-12 persons will formed from one assisted living facility. All of them will undergo an individual interview to assess their wishes for the nature-based activities.~Participants meet in a closed group for 9 times once a week for 10 weeks. All 2-4 hour sessions will include nature-based activities and mutual discussions about the experiences of nature and loneliness.~2 professionals will facilitate and observe the group more thoroughly, give feedback to each other, and make use of group dynamics. They write diaries on each session and receive feedback from their trainers. The groups are objective oriented (aiming to alleviate loneliness, to improve participants' self-efficacy), client oriented and aim with favorable group dynamics to mature, self-directing group in which the participants have made friends with each other and want meet with each other without the facilitators after the official group intervention is over.
Study NCT06574464 — intervention group
Intervention type: OTHER
Intervention: BIG SCORE
Description: The trauma BIG score is used to predict posttraumatic injury severity and mortality. It was originally designed for the pediatric population. The score is calculated using the Base Deficit (BD), International Normalized Ratio (INR), and Glasgow Coma Scale (GCS) score on admission using the following formula:~BIG score = (admission BD) + (2.5 × INR) + (15 - GCS).
Study NCT06574464 — intervention group
Intervention type: OTHER
Intervention: Glasgow coma scale
Description: The Glasgow Coma Scale is a neurological assessment tool used to evaluate the level of consciousness of a patient. It assesses three items: eye-opening (spontaneous, 4 points; to verbal stimuli, 3 points; to pain stimuli, 2 points; no response, 1 point); verbal responses (oriented, 5 points; confused but coherent speech, 4 points; inappropriate words, 3 points; incomprehensible speech, 2 points; no response, 1 point); and motor responses (obeys commands, 6 points; localizes pain, 5 points; withdraws from pain, 4 points; flexes in response to pain, 3 points; extends in response to pain, 2 points; no response, 1 point). The total GCS score is obtained by summing the scores for the three items, and it ranges from 3 to 15.
Study NCT06574464 — intervention group
Intervention type: OTHER
Intervention: Revised Trauma Score
Description: The Revised Trauma Score (RTS) is a physiological scoring system used to assess the severity of a traumatic injury. It considers three key parameters, Glasgow Coma Scale (GCS), Systolic Blood Pressure (SBP), and Respiratory Rate (RR), with a total score of 12 points. The study team retrospectively computed the RTS on admission by retrieving the GCS score, SBP, and RR per minute from the hospital's automated systems and archives.
Study NCT06574464 — intervention group
Intervention type: OTHER
Intervention: Injury Severity Score
Description: The Injury Severity Score (ISS) is an anatomical scoring system used to assess the severity of injuries sustained by trauma patients. It provides a numerical value based on the anatomical regions of the body affected by trauma and the severity of those injuries. The ISS is calculated by dividing the body into six regions: the head/neck, face, chest, abdomen/pelvis, extremities, and external. Each region is assigned a score ranging from 1 to 6, with 1 indicating minor injury and 6 indicating severe injury. The highest score from each region is squared and then the scores are summed to calculate the overall ISS.
Study NCT05674708 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Fat intake
Description: Four different sources of dietary fat
Study NCT06501937 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Influencer marketing
Description: Participants watched online survey-imbedded promotional videos featuring influencers
Study NCT06501937 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Influencer marketing
Description: Participants watched online survey-imbedded promotional videos featuring influencers
Study NCT05163535 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VM-1500A-LAI
Description: VM-1500A (parent drug of elsulfavirine) IM injection dosage form
Study NCT05163535 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: ELPIDA®
Description: Elsulfavirine capsules
Study NCT05486702 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time Restricted Eating
Description: Time restricted eating (TRE) can be divided into early TRE (eTRE) and late TRE (lTRE), depending on the time of day of the eating window.
Study NCT05351567 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EDUCATIONAL PROGRAM CREATED ACCORDING TO TRANSFORMATIONAL LEARNING THEORY
Description: EDUCATIONAL PROGRAM CREATED ACCORDING TO TRANSFORMATIONAL LEARNING THEORY FOR INFERTILITY FEMALES
Study NCT05633862 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: BI 1015550