AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04195633 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Mofetil
Description: Given IV or PO
Study NCT04195633 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate Sodium
Description: Given PO
Study NCT04208477 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: one site blockade of the stellate ganglion
Description: Ultrasound guided one site blockade of the stellate ganglion.
Study NCT05449600 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thermotape
Description: Thermotape will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.
Study NCT05449600 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tegaderm
Description: Tegaderm™will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.
Study NCT05449600 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kind
Description: Thermotape will be applied along the left and right forearm. One piece of tape, one inch wide by two inches long, will be applied to each arm. The location the tape, when applied, will be randomized. Altogether, two pieces of this particular tape will be applied, one to each forearm.
Study NCT05332483 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Megestrol Acetate
Description: Megestrol acetate, 160 mg daily (two 40mg tablets twice a day), for a minimum of 18 days.
Study NCT04192578 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: remote ischemic conditioning
Description: RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently.
Study NCT05370859 — intervention group
Intervention type: OTHER
Intervention: There is no intervention for this study
Description: There is no intervention or exposure for this study
Study NCT04726371 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Generic Best Practices
Description: GBP consists of (1) Massachusetts Executive Office of Health and Human Services distribution of standard guidelines and policies for public health prevention and management of COVID and (2) standard virtual training of the staff of the group homes in these generic COVID-19 prevention practices including recommended use of hand washing, use of PPE, and symptom-triggered screening. Group homes randomized to this intervention will receive standard recommended and fully vetted best practices with respect to preventing and managing COVID-19 based on recommendations by the CDC and on consultation with leading national experts in infectious disease working with the Commonwealth of Massachusetts. The control condition does not represent inferior or substandard practice. As findings occur and as policy leads to adjustments in recommendations during the course of the study, the GBP condition will incorporate recommendations that are appropriate and up-to-date with CDC and state policy.
Study NCT04726371 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tailored Best Practices
Description: TBP consists of optimized, tailored, and highly specific COVID-19 best practices and training materials specific to the setting, staff, and residents with SMI and ID/DD in congregate living settings based on the comparative effectiveness of different types, intensities, and combinations of COVID-19 prevention practices (screening, isolation, contact tracing, use of PPP, vaccination) specifically modeled for residents and staff of congregate living settings for people with ID/DD and SMI derived by a simulation model. Results from this modeling process will be provided to stakeholders to support decision makers in prioritizing resources and practices with the greatest impact on reducing COVID-19 tailored for people with SMI and ID/DD in congregate living settings. This process to determine the content of TBP will occur as part of this study prior to randomization.
Study NCT04195633 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total-Body Irradiation
Description: Undergo total-body irradiation
Study NCT04195633 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: Given IV
Study NCT05648734 — intervention group
Intervention type: DRUG
Intervention: Corticosteroids + Colchicine + Pirfenidone for ≥ 14 days
Description: (≥ 20 mg prednisolone or its equivalent for ≥ 10 days) + Colchicine (1 mg/day for ≥ 10 days) + Pirfenidone (267 mg TID for ≥ 14 days)
Study NCT05141032 — intervention group
Intervention type: PROCEDURE
Intervention: Endoscopic Submucosal Dissection with Pathfinder/Overtube device
Description: Removal of gastrointestinal polyps via ESD
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration
Description: Undergo bone marrow aspiration
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Echocardiography
Description: Undergo echocardiography
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT or PET/CT
Study NCT04195633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study NCT05604508 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Many posters with prices
Description: No poster number or price restrictions
Study NCT05604508 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Many posters, no prices
Description: No poster number restrictions, but price restrictions
Study NCT05604508 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fewer posters, no price restrictions
Description: Poster number restrictions, but no price restrictions
Study NCT05293470 — intervention group
Intervention type: OTHER
Intervention: Piqray
Description: There is no treatment allocation. Patients administered Piqray by prescription will be enrolled.
Study NCT05641441 — intervention group
Intervention type: RADIATION
Intervention: Stereotactic radiosurgery
Description: Stereotactic radiosurgery
Study NCT06521645 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: electrical stimulation is given through needles inserted into the skin
Study NCT06521645 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham needle
Description: needles are inserted shallowly into the skin
Study NCT06149286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Odronextamab
Description: Administered by intravenous (IV) infusion
Study NCT06149286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Administered orally (PO)
Study NCT06149286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Administered by IV infusion, or subcutaneously (SC)
Study NCT05856344 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spherical tip noncompliant balloon
Description: The main difference of this experimental balloon is the spherical tip, other parameters are consistent with regular noncompliant balloons.
Study NCT05856344 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Regular noncompliant balloon
Description: The balloon is designed as tapered-tip.
Study NCT05257486 — intervention group
Intervention type: DEVICE
Intervention: Xoft eBx
Description: The Xoft Axxent Electronic Brachytherapy (eBx) System allows for the administration of high dose rate brachytherapy treatments using an electronic source
Study NCT05170386 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive training Therapy
Description: Cognitive training Therapy include: Writing the reminiscences~• Solving a table• Writing a letter making a calendar and writing a note about the daily activities on it Facing patients' fears instead of avoiding them.Using role-playing to prepare for potentially problematic interactions with others.Learning to calm one's mind and relax one's body.
Study NCT05170386 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: instructive conventional treatment
Description: instructive conventional treatment breathing relaxation exercise inform of diaphragmatic breathing Practice sleep hygiene such as keeping a regular sleep schedule. Get regular exercise. Minimize noise. Minimize light. Manage the temperature so that you're comfortable.
Study NCT06184750 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy
Study NCT06184750 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT06184750 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mammography
Description: Undergo mammography
Study NCT06184750 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06184750 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamoxifen
Description: Given PO
Study NCT04765384 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad26.COV2.S
Description: Participants will receive intramuscular (IM) injection of Ad26.COV2.S.
Study NCT05411692 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Functional electrical stimulations and motor priming exercise
Description: One pair of surface stimulation electrodes is placed on the subject's skin above the flexor digitorum superficialis and the flexor digitorum profundus muscles to generate finger flexion. The Second pair of electrodes is placed on the subject's skin, above the median~nerve, to generate thumb flexion. The third pair of electrodes is placed on the subject's skin, above the extensor digitorum muscle, to generate finger extension. Motor priming exercises will be done (functional task practice, FTP) for 20 minutes. Participants will be asked to spend at least 20 minutesDuration of training will be 4 weeks, 5 days per week, one session per day, and one hour per session.
Study NCT05411692 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Functional electrical stimulations
Description: Stimulation parameters are (1) balanced, biphasic, current-regulated electrical pulses; (2) pulse amplitude from 8 to 50 mA (typical values 17- 26 mA); (3) pulse width 250 ms; and (4) pulse frequency from 20 to 70 Hz (18). Trancutaneous stimulation will be delivered bilaterally with surface electrodes placed on the volar aspect of each wrist targeting the distribution of the median nerve. One pair of surface stimulation electrodes is placed on the subject's skin above the flexor digitorum superficialis and the flexor digitorum profundus muscles to generate finger flexion. The Second pair of electrodes is placed on the subject's skin, above the median~nerve, to generate thumb flexion for 20 minutes
Study NCT05411692 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conventional physical therapy
Description: a structured exercise protocol targeting strength (2 days/week) and endurance (3days/week) training
Study NCT06392945 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cognitive Treadmill Walking Training with Rhythmic Auditory Cueing (CTW+RAC) group
Description: Participants in the CTW+RAC group participate in 12-session programs administered for 30 minutes each session, 3 times per week for 4 weeks. To increase adaptability to rhythmic auditory cueing prior to cognitive treadmill walking training, participants are required to keep stepping on their feet while listening to the auditory cueing using a metronome program (Metronome APP) for 5 minutes of warm up. Then they start walking on a treadmill with a target speed and perform a cognitive task concurrently while listening rhythmic auditory cueing. According to previous research, the target treadmill speed at week 1, week 2, week 3, and week 4 is gradually increased from 90%, 100%, 110%, to 120% baseline walking speed of comfortable walking on the ground. The beat of rhythmic auditory cueing using the Metronome APP on the smartphone is set at 110% of baseline cadence of comfortable walking on the ground based on a previous study in individuals with stroke.
Study NCT06392945 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Treadmill Walking Training (CTW) group
Description: Participants in the CTW group will participate in 12-session programs administered for 30 minutes each session, 3 times per week for 4 weeks. They will start stepping on the ground at comfortable pace for 5 minutes of warm up. Then they will start walking on a treadmill with a target speed and perform a cognitive task concurrently without rhythmic auditory cueing. Same cognitive training and target treadmill speed will be used as the CTW+RAC group during cognitive dual-task treadmill walking. Three cognitive training programs will be the verbal fluency, arithmetic, and visual distinguish tasks. The target treadmill speed will be gradually increased from 90% at week 1, to 100% at week 2, to 110% at week 3, to 120% baseline walking speed of comfortable walking on the 10 meters walk test at week 4.
Study NCT06392945 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Treadmill Walking Training (TW)
Description: Participants in the TW group will participate in 12-session programs administered for 30 minutes each session, 3 times per week for 4 weeks. They will start stepping on the ground at comfortable pace for 5 minutes of warm up. Then they will start walking on a treadmill with a target speed only, without concurrent performing a cognitive task and no listening rhythmic auditory cueing. Same target treadmill speed will be used as the other two groups during treadmill walking. The target treadmill speed will be gradually increased from 90% at week 1, to 100% at week 2, to 110% at week 3, to 120% baseline walking speed of comfortable walking on the ground.
Study NCT05944705 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: Immune Support Supplement
Description: Cannabinoid and co-active emulsion
Study NCT04774757 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Para-aortic lymph node dissection
Description: Para-aortic lymph node dissection was defined as the dissection of para-aortic lymph nodes located below renal vein and above the bifurcation of iliac artery.
Study NCT05915403 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Fibromyalgia Impact Questionnaire
Description: diagnostic tests
Study NCT05364632 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Intervention to Increase Physical Activity
Description: The educational program will consist of 2 classes held once a week, each lasting 90 minutes. The classes will be based on an education videotape, presentations and group discussions. The first class will address the asthma education. The second class will be about the current international physical activity recommendations and the importance and benefits of being physically active. The behavioural intervention will be performed in 8 weekly goal-setting consultation, face-to-face, each lasting until 90 minutes. Patients will be offered a commercially-available activity tracker to wear during 3 days prior to each consultation. According to their own physical activity (PA) data and the behavioural change stage, an individual action plan will be established to increase physical activity. Each participant will receive individual counselling with the goal of increasing participation in PA and reducing their sedentary time.
Study NCT05364632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Training
Description: The same initial educational program described for the Behavioral Intervention group will be delivered to this group. Each aerobic training session will consist of 45 minutes divided into 5 minutes of warm-up, 35 minutes of aerobic exercise and 5 minutes of cool-down. During physical training, heart rate and level of respiratory distress will be monitored. The intensity of aerobic physical training will be based on the heart rate (HR) corresponding to one third of the difference between the anaerobic threshold (LA) and the respiratory compensation point (CRP). The patient may interrupt physical exercise if he presents any clinical symptoms and/or respiratory discomfort, returning as soon as his respiratory condition improves.
Study NCT04564482 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: CRT
Description: 50 Gy in 2 Gy fractions over 25 working days + capecitabine 1650 mg/m2/d PO
Study NCT04564482 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: SCPRT
Description: 25 Gy in 5 Gy fractions over 5 working days
Study NCT04564482 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: CROSS Protocol
Description: 41.4 Gy in 1.8 Gy fractions over 23 working days + carboplatin AUC of 2 mg/ml/min + paclitaxel 50 mg/m2 IV Q1W
Study NCT04564482 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: PD-L1 PET
Description: 10 mg atezolizumab IV followed by 37 MBq 89Zr-atezolizumab IV. PET imaging will be done before neoadjuvant CRT/SCPRT (day 0) and between day 10-14 during CRT/SCPRT.
Study NCT05754008 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AURORA Care Strategy
Description: Participants will be invited to partake in three telemedicine visits with the care navigator during the months following diagnosis. The visits center around proactive and tailored T2D self-management support.
Study NCT04963491 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Personalized TKA prosthesis
Description: TKA prosthesis that is designed and manufactured according to the patient's knee joint anatomy
Study NCT04963491 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Zimmer NexGen prostheses
Description: Commercial products used on a large scale
Study NCT05577845 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ramosetron
Description: Ramosetron, 4 weeks
Study NCT05577845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ramosetron
Description: Ramosetron, 4 weeks
Study NCT04225663 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Guided Meditation
Description: Participants will meditate in response to the guidance provided by a trained meditation coach in person.
Study NCT06074588 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab tirumotecan
Description: 4 mg/kg of MK-sacituzumab tirumotecan by IV infusion
Study NCT06074588 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: 75 mg/m\^2 of docetaxel by IV Infusion
Study NCT06074588 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pemetrexed
Description: 500 mg/m\^2 of pemetrexed by IV infusion
Study NCT06056297 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mavorixafor
Description: Mavorixafor will be administered per schedule specified in the arm description.
Study NCT06056297 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered per schedule specified in the arm description.
Study NCT05662462 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DEXCOM G7 PRO Continuous Glucose Monitor
Description: Participants in the intervention arm will be provided with DEXCOM® G7 PRO CGM sensors and transmitters. The Dexcom G7 CGM system is accurate and safe in pregnant individuals with diabetes. Participants will be taught how to place and remove CGM sensors by a trained research nurse, and will be given sensors to change themselves at home every 10 days. Of note, the DEXCOM® G7 PRO can be applied as a patch on the abdomen, arm, or upper buttocks, is well-tolerated in pregnancy, and does not require calibration. Our mHealth app will allow for wireless synchronization with the CGM sensor so that data are seamlessly reported back to the healthcare team.
Study NCT05662462 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Patient mHealth app linked to a provider dashboard
Description: The mHealth app is based on our team's prototype intervention developed at our study site. The mHealth app provides diverse functions, including education, reminders, care goals, care pathway recommendations, CGM data and PROs reporting and monitoring, messaging and video conferencing, and a calendar function. Content is based on clinical guidelines for diabetes in pregnancy. Participants will be directed to appropriate resources and online learning to help them navigate the app and its resources. PROs in the mHealth app will be embedded to address health and social needs, and rule-based algorithms will provide tailored care goals, show care pathways, and establish the frequency of elicited PROs.
Study NCT05662462 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care team coaching for medical and social needs (HUB)
Description: Participants will be screened at enrollment and throughout the intervention for social needs using a survey adapted from validated instruments, such as the Accountable Health Communities Health-Related Social Needs Screening Tool. The care team will refer participants with affirmative responses to the HUB through the provider dashboard to address social needs (e.g., food insecurity, housing, employment). HUB community health workers will perform comprehensive social needs assessments and connect participants to community resources through care pathways, a defined action plan addressing patient needs which is recorded and tracked.