AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06477380 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACCEPT intervention
Description: * Training package (1 day)~* A toolkit/manual for clinicians to guide them through the disclosure process~* Trauma-informed changes to the physical environment~* Monthly trauma-focussed reflective group for care co-ordinators
Study NCT04953806 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Step-CBT
Description: Participants will complete Step-CBT, an integrative 8-week physical activity and cognitive behavioral therapy (CBT) intervention, delivered by a licensed clinical psychologist. Sessions will take place once per week for 60 minutes using VA Video Connect. Each session will include core components 1) Reviewing physical activity goals, prescribing new step count goal, and problem-solving barriers and 2) The weekly CBT intervention module.
Study NCT04499833 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: liver transplant
Description: liver transplant
Study NCT06472687 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FIFA 11+ warm-up exercise training
Description: FIFA 11+ warm-up training program was applied to the experimentel group. control group (CG) did their usual warm-up program.
Study NCT06472687 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: warm-up exercise training
Description: exercise training
Study NCT06786871 — intervention group
Intervention type: PROCEDURE
Intervention: IVF treatment
Description: Methods or procedures for the in vitro processing of human oocytes, sperm, or embryos for fertility purposes
Study NCT06782711 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cranioplasty
Description: In this pivotal study of a medical device, patients with bone loss undergo a computed tomography scan, which is used to create a three-dimensional model of the lesion. After validation, the model is printed using PEEK material, and subsequently, the skull is repaired through cranial reconstruction (cranioplasty).
Study NCT06782711 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: customized skull implants made of polyetheretheretherketone (PEEK) using 3D printing
Description: customized skull implants made of polyetheretheretherketone by three-dimensional printing in patients undergoing cranioplasty
Study NCT06787547 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IVL(Sonico-CX)
Description: SONICO-CX® balloon matched 1:1 to the reference vessel diameter, was advanced to the target lesion to pretreat
Study NCT06786247 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ActivaTeen
Description: The ActivaTeen app is built on HIPAA-compliant instance of a popular messaging software. Participants in the treatment group can access the app at any time via desktop or mobile, where they can find features designed to enhance their receipt of BA therapy.~These features include: weekly BA skills and homework completion support, in-app messaging with their BA therapist, mood and activity tracking and data visualizations, chatbot check-ins on progress and guided problem-solving around barriers, and moderated peer support using the ActivaTeen app. The app will have a moderator, who is part of the study team, to manage peer-to-peer interactions within ActivaTeen.
Study NCT06786247 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Activation
Description: Behavioral activation therapy involves individual weekly sessions with a trained therapist for 12 weeks. The sessions are completed either in-person or via telehealth. The treatment focuses on behavioral manifestations of depression such as isolating, and how these behaviors are interconnected with low mood and depressive emotions. BA helps patients find ways to engage in behaviors that are meaningful to them based on their values, priorities, and goals, with the aim of creating positive loops between doing meaningful activities and improved mood. The therapist provides structure and problem-solving for activating these behaviors and keeping track of changes over time.
Study NCT06786247 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral Activation
Description: Behavioral activation therapy involves individual weekly sessions with a trained therapist for 12 weeks. The sessions are completed either in-person or via telehealth. The treatment focuses on behavioral manifestations of depression such as isolating, and how these behaviors are interconnected with low mood and depressive emotions. BA helps patients find ways to engage in behaviors that are meaningful to them based on their values, priorities, and goals, with the aim of creating positive loops between doing meaningful activities and improved mood. The therapist provides structure and problem-solving for activating these behaviors and keeping track of changes over time.
Study NCT06783933 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: surgical or interventional validation
Description: surgical or interventional validation
Study NCT06784986 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: The Conventional Insufflation System
Description: The Conventional Insufflation System employs standard CO2 insufflation techniques for maintaining intra-abdominal pressure during laparoscopic and robotic surgeries. It serves as the base for comparison with the AirSeal® System.
Study NCT06784986 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AirSeal® System
Description: The AirSeal® System consists of an insufflation, filtration, and recirculation system (AirSeal® IFS), a triple-lumen filtered tube set, and a valve-free trocar (AirSeal® Access Port). This innovative system allows peritoneal access and pneumoperitoneum maintenance without a mechanical seal, reducing CO2 usage and associated complications.
Study NCT06786221 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mini-implant template
Description: The proposed structure will be made of three main components: a tooth guide part, a gingival guide part, and a steering part. The tooth guide and gingival guide parts are firmly connected by fracture lines. The mini-implant guide part is specifically designed to accommodate the angle and position required for miniscrew insertion. On the basis of the resin guide plate, add a guide hole structure and change it to simulate the patient's actual tooth root condition.~During usage, the guide can be pre-designed in accordance with the desired planting position and direction of the patient's mini-implant, enabling precise guidance during the implantation process. The designed guide's data is inputted into EnvisionTEC Vida 3D printer to create the mini-implant guide. Prior to the implantation of the mini-screw, patients will be informed about the potential risks and required to sign an informed consent form.
Study NCT06787209 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Program to improve lumbopelvic function.
Description: Each individual will receive a weekly session log at the start of the intervention, allowing them to record the total number of sessions performed between in-person visits and the perceived exertion.~In the strengthening phase, both compound and isolated exercises will be performed. These exercises will be of low intensity and maintained for prolonged periods until the patient reaches fatigue or can no longer perform the repetitions correctly. If the patient reaches 40 repetitions, the exercise will be progressed in difficulty. The patient will have one minute of rest after each set.~Each session will include a total of 4 sets focused on the gluteal muscles The speed of execution for each repetition will be between 4-6 seconds. After the strengthening phase, three unilateral static stretches targeting the hip flexors will be performed, each lasting one minute.~The entire program will be performed using bodyweight exercises and adapted exercises that can be done at home.
Study NCT06787209 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: generic health care
Description: The patients will receive 10 physiotherapy sessions at the health center throughout 4 weeks.They will be taught active exercises and undergo passive therapies to address their low back pain. Each session will last approximately 30 minutes.~The intervention will therefore be variable depending on the assigned physiotherapist, as there is no standardized protocol for action.
Study NCT06786507 — intervention group
Intervention type: DRUG
Intervention: Ustekinumab 90 mg
Description: Ustekinumab is a human monoclonal IgG1 antibody that blocks the p40 subunit of both IL-12 and IL-23 this antagonistic action inhibits the interaction of these cytokines with the IL-12Rβ1 receptor. The IL-12Rβ1 receptor is found on the surface of NK cells and T cells which reduces inflammation and alters the body's immune response
Study NCT06786507 — intervention group
Intervention type: DRUG
Intervention: Infliximab
Description: Infliximab is a biological therapy/immunotherapy medication designed to stimulate the body's immune system and treat certain diseases. Infliximab is a purified, recombinant DNA-derived chimeric IgG monoclonal antibody protein that contains both murine and human components that inhibit tumor necrosis factor-alpha (TNF-α). TNF-α is a signaling protein involved in acute phase reactions and systemic inflammation. Macrophages, CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons produce TNF-α. This TNF-α inhibition inhibits the inflammatory reaction's cascade, leading to improved disease condition inflammatory bowel disease
Study NCT06087601 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.9% Sodium chloride
Description: us-guided bilateral genicular nerves sham block with 0,5ml 0,9% normal saline
Study NCT06087601 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 95% ethanol
Description: us-guided bilateral genicular nerves neurolysis with 0,5ml 95% ethanol
Study NCT06007092 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HPVDC injection level dose 1
Description: patient receive 3 injections of vaccine at the same level dose
Study NCT06007092 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo injection level dose 1
Description: patient receive 3 injections of vaccine at the same level dose
Study NCT06007092 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HPVDC injection level dose 2
Description: patient receive 3 injections of vaccine at the same level dose
Study NCT06007092 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo injection level dose 2
Description: patient receive 3 injections of vaccine at the same level dose
Study NCT06426641 — intervention group
Intervention type: DEVICE
Intervention: Polyethylene
Description: There is no intervention
Study NCT05473065 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multiaxial Prosthetic Foot Emulator
Description: Participants will walk in the laboratory with the multiaxial Prosthetic Foot Emulator (PFE) in three foot modes corresponding to commercial prosthetic study feet. Walking conditions will include self-selected comfortable, slow, and fast speeds, inclines, cross slopes, and uneven terrain.
Study NCT05473065 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Commercially available prosthetic feet
Description: Participants will walk in the laboratory with the commercial prosthetic study feet in three foot modes corresponding to commercial prosthetic study feet. Walking conditions will include self-selected comfortable, slow, and fast speeds, inclines, cross slopes, and uneven terrain.~Additionally, participants will be fit with one of the commercial prosthetic study feet and wear it at home and in the community for approximately one week. Participants will return to the laboratory to follow-up testing, and will complete the community trial with each of the three commercial prosthetic study feet.
Study NCT06014515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-FDG
Description: Each subject will undergo a dynamic 18F-FDG PET/CT scan (this drug is FDA approved) and a dynamic 11C-butanol PET/CT scan (this drug is under an IND) on the EXPLORER total-body PET/CT system. The two scans will be performed on the same day or within a period of up to two weeks depending on subject, imaging agent and scanner availability.
Study NCT06014515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 11C-butanol
Description: Each subject will undergo a dynamic 18F-FDG PET/CT scan (this drug is FDA approved) and a dynamic 11C-butanol PET/CT scan (this drug is under an IND) on the EXPLORER total-body PET/CT system. The two scans will be performed on the same day or within a period of up to two weeks depending on subject, imaging agent and scanner availability.
Study NCT04762563 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IASTM application
Description: IASTM application .
Study NCT04762563 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio Tape® Tex Gold)
Description: Kinesio Tape® Tex Gold)
Study NCT06464341 — intervention group
Intervention type: OTHER
Intervention: Observational study no intervention
Description: Observational study no intervention
Study NCT04783935 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mavenclad®
Description: No intervention was administered as a part of this study. Participants who had received Mavenclad® up to 2 years (Year 1 and 2) in the parent study MS700568_0022 (NCT03364036) were enrolled into this extension study and will be assessed up to 2 years follow-up (Year 3 and 4).
Study NCT06636071 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: setrusumab
Description: A fully human sclerostin neutralizing monoclonal antibody (mAb) administered once a month (QM) via intravenous (IV) infusion
Study NCT06636279 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Gas bubble technique
Description: Inject the sterile air into the anterior chamber after the conventional cataract surgery to reduce corneal endothelial damage
Study NCT06247215 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally tailored resilience-building intervention
Description: A booklist teaching resilience skills for advance care planning discussions
Study NCT05906537 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SKB410 for injection
Description: SKB410 for injection is administered every 2 weeks (q2w) until radiographic disease progression (PD), intolerable toxicity, death, or discontinuation of treatment, whichever occurs first.
Study NCT05063695 — intervention group
Intervention type: OTHER
Intervention: Multimodal Erector spinae catheter protocol
Description: Patients either received multimodal epidural or ESP protocol
Study NCT04987931 — intervention group
Intervention type: DRUG
Intervention: Talazoparib
Description: This retrospective chart review study focuses on patients with HER2- ABC with gBRCA1/2m initiating talazoparib on or after October 16, 2018 and ≥18 years of age at initiation of talazoparib.
Study NCT05009134 — intervention group
Intervention type: BIOLOGICAL
Intervention: There is no intervention in this study.
Description: There is no intervention in this study.
Study NCT05996822 — intervention group
Intervention type: DRUG
Intervention: ACF injection
Description: AcF injection 1 month after a DXM injection
Study NCT05518071 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CRGD-ZW800-1
Description: Intravenous single bolus injection of the targeted NIR fluorophore cRGD-ZW800-1. This targeted 800nm zwitterionic fluorophore developed by the Hospital Pharmacy Department of LUMC consists of the fluorophore ZW800-1 conjugated to the cRGD peptide
Study NCT06104566 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: lisaftoclax +BTK inhibitor
Description: lisaftolax + BTK inhibitor
Study NCT06104566 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BTK inhibitor
Description: BTK inhibitor
Study NCT04835064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: Albumin combined with paclitaxel 125mg/m2 intravenous infusion, Day 1, 8, 15
Study NCT04835064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Intravenous infusion of 1000 mg/m2 was given for more than 30min on days 1, 8, and 15, and repeated every 4 weeks
Study NCT04835064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mFOLFIRINOX
Description: Oxaliplatin 85 mg/m2 intravenous infusion for 2 h, Day 1;LV 400 mg/m2 intravenous infusion for 2 h, Day 1;Irinotecan 150 mg/m2 was added 30 min after intravenous infusion for 90 min, day 1;This was immediately followed by a continuous intravenous infusion of 5-FU 2400 mg/m2 for 46 h.Repeat every 2 weeks.
Study NCT04241510 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio Taping
Description: Kinesio Taping is a special taping method developed by Dr. Kenzo Kase in 1973. This technique triggers natural healing responses of human body by activating nervous and circulatory systems. The tapes are thin, latex-free, cotton, porous and anti-allergenic, with equal thickness of epidermis. It has elastic properites which allows the tape to elongate to %55-60 of its original lenght. Tape can be used up to 1 week even after sweating or cleaning with water. There are different application techniques for different purposes. Facilitation technique facilitates muscle contractions and supports muscle function. Mechancial correction technique is used for joint positioning and correcting motion of muscle-joint dynamics.
Study NCT05768529 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: U16
Description: A conditioning chemotherapy regimen of fludarabine and cyclophosphamide will be administered before U16 treatment.
Study NCT05518071 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraoperative near-infrared fluorescence imaging
Description: Intraoperative imaging will be performed with at least one of the following CE-marked near-infrared (NIR) fluorescence imaging systems: Quest Spectrum imaging platform (v2/3.0) for open-procedures, the Olympus or Karl-Storz system for the diagnostic laparoscopy or the Intuitive Surgical Da Vinci Xi (Firefly-mode) for minimally invasive robot-assisted procedures. With a NIR-imaging system a potential fluorescent signal of the tumor can be evaluated. Furthermore, the Quest Spectrum platform will also be used for evaluation of ex-vivo fluorescence of resected tissue on the back table (Back table imaging) and pathology department (ex-vivo imaging), which shall be performed during and after every procedure.
Study NCT04828941 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electronic Headache Diary
Description: The electronic headache diary is an app-based diary that permits the registration of headaches, their acute treatment and their associated work incapacity. It also permits real-time monitoring of these data.
Study NCT04828941 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Paper Diary
Description: The paper diary permits the registration of the same variables as the electronic diary in paper format.
Study NCT05561413 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness and exercise
Description: The mindfulness and exercise group aims to gradually increase participants exercise levels so that they begin to achieve the recommended levels along with the strengthening exercises for all major muscle groups. Along side this mindfulness will be introduced and built on to help consolidate exercise uptake and help manage symptoms experienced by the participants.
Study NCT05561413 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness
Description: The delivery of this practice will be through the app downloaded by participants. The practice based on mindfulness based stress reduction (MBSR). Will build on practice over the 8 weeks.
Study NCT01829009 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise Group
Description: An individualized resistance exercise program wil be applied twice a week by an expert physiotherapist. Every 2 weeks, intensity will be reassessed by the same physiotherapist. Weekly, participants will be asked about incidents such as the occurrence of falls or hospitalizations during this study period.~Physical performance and functional status will be assessed by the blind investigator at weeks 6,12 and 24
Study NCT06485895 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: test IGRA
Description: BLOOD SAMPLES
Study NCT06485895 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: TEST QUATIFERON TB Gold Plus
Description: BLOOD SAMPLES
Study NCT05063084 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Optiflow - HFNO
Description: Pre-oxygenation: HFNO with a 2 L/Kg/min flow during 2 min with 100% FiO2 Oxygenation: during the tracheal intubation, HFNO with a 2 L/Kg/min flow during 2 min with 100% FiO2
Study NCT05063084 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Classic
Description: Pre-oxygenation: with facemask during 2 min with 100% FiO2, flow 6 to 8L/min. No oxygenation during the tracheal intubation
Study NCT05825963 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Psyllium
Description: The participants select hamburgers randomly by themselves, with or without (control) 12 g of psyllium, each containing 85 g of hamburger bread, 160 g of 20% fat beef, 2.56 g of salt, and 1.28 g of pepper, and asked to consume them with 200 ml of water.
Study NCT05846568 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GR1801
Description: The injection solution GR1801 does not contain preservatives. The excipients include histidine/histidine hydrochloride (20mM), trehalose (90 mg/mL), disodium EDTA (0.372mg/mL) and polysorbate 80 (0.5 mg/mL). The pH value is 5.8 and each bottle contains 2mg of GR1801 protein. The packaging material is a borosilicate glass tube injection bottle (2mL) with a halogenated butyl rubber stopper for injection and an aluminum-plastic composite cap for antibiotic bottles.
Study NCT05846568 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Human Rabies Immunoglobulin(HRIG)
Description: The HRIG is a Chinese licensed Human Rabies Immunoglobulin produced by BOYA-BIO, which are derived from human plasma, and then purified and filled in the injectable vial form.