AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05808543 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Both EARS training package (BEARS)
Description: The BEARS training package comprises of three games addressing different hearing functions: speech-in-noise perception, music listening and sound-source localisation. Each game is based on an audio-visual task performed through a virtual-reality interface. Players are guided through on-screen visual prompts to support the gameplay with feedback given on their performance and progress through levels of increasing difficulty. The BEARS training package design allows for the training to be self-administered, played anywhere and at any time. There is no upper limit to the frequency of use of the BEARS training package, it is advised to play the games for a minimum of 1 hour a week over a minimum of 2x 30-minute sessions, all three games will need to be played.
Study NCT05808543 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: This is an annual review appointment with the patient and their clinician. This could be face-to-face, virtual video consultation, questionnaire, or be cochlear remote care checks. As a minimum this review will check the following: Microphone covers changed, Reported or recorded device use, all external and internal equipment working (known through no reported or recorded degradation in hearing ability). During the appointment, the clinician would establish if there were any concerns regarding the cochlear implant functioning and the patient's rehabilitation programme. They will then make any repairs or adjustments to the device and manage additional support and contact as required. Between the annual review appointments patients can attend the implant centre for repair appointments or have spare equipment posted. There is no limit to the level of contact between the patient and the implant centre.
Study NCT05808543 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: This is an annual review appointment with the patient and their clinician. This could be face-to-face, virtual video consultation, questionnaire, or be cochlear remote care checks. As a minimum this review will check the following: Microphone covers changed, Reported or recorded device use, all external and internal equipment working (known through no reported or recorded degradation in hearing ability). During the appointment, the clinician would establish if there were any concerns regarding the cochlear implant functioning and the patient's rehabilitation programme. They will then make any repairs or adjustments to the device and manage additional support and contact as required. Between the annual review appointments patients can attend the implant centre for repair appointments or have spare equipment posted. There is no limit to the level of contact between the patient and the implant centre.
Study NCT04735484 — intervention group
Intervention type: DEVICE
Intervention: Gait analysis
Description: Collecting movement data whilst participants walk
Study NCT06355232 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Covid-19 vaccine
Description: Recombinant SARS-CoV-2 spike protein with Advax-CpG55.2 adjuvant
Study NCT06355232 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Influenza vaccine
Description: Inactivated seasonal influenza vaccine with Advax-CpG55.2 adjuvant
Study NCT06423274 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: fundus photography
Description: using artificial intelligence to identify diabetic retinopathy using fundus photography
Study NCT06423274 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: optical coherence tomography
Description: detect diabetic retinopathy and diabetic macular edema by optical coherence tomography
Study NCT06423274 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: fundus fluorescence angiography
Description: detect diabetic retinopathy by fundus fluorescence angiography
Study NCT04867096 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Patients in arm A (interventional) will carry out a physical activity intervention during 3 months. Patients should perform an interval training program on cycle-ergometer during 3 sessions per week.
Study NCT01209013 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medlight PDT Balloon
Description: Medlight PDT Balloon will be used once to apply the laser light treatment
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopy
Description: Endoscopy will be performed to confirm eligibility, apply photodynamic therapy, assess esophageal condition and effectiveness of the therapy
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopy with biopsy
Description: Endoscopy with collection of esophageal tissue will be performed at screening to confirm eligibility and at Week 13 (final visit) to assess effectiveness
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electrocardiogram
Description: Resting electrocardiogram will be performed at screening (unless one has been performed within 30 days prior to screening) to measure heart function
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Chest x-ray
Description: A chest X-ray will be performed at screening (unless one has been performed within 90 days prior to screening) to provide several pictures of the chest to rule out any lung abnormalities
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blood collection
Description: Blood samples for laboratory tests will be taken to assess the overall condition
Study NCT01209013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tissue sample collection
Description: Esophageal tissue samples will be collected before the porfimer sodium injection and on four separate occasions after the injection (22-26 hour-, 40-50 hour-, 96-120 hour-intervals, and 13 weeks) to measure concentrations of oligomers in a subgroup of 12 patients.
Study NCT06305832 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rezvilutamide
Description: Specifications of 80 mg; orally, once a day
Study NCT06305832 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Androgen deprivation therapy (ADT)
Description: Androgen deprivation therapy (ADT), the ADT used by each subject will be determined by the investigator,and the dose and frequency of administration will be consistent with the prescription information
Study NCT06305832 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Androgen deprivation therapy (ADT)
Description: Androgen deprivation therapy (ADT), the ADT used by each subject will be determined by the investigator,and the dose and frequency of administration will be consistent with the prescription information
Study NCT06305832 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: SRT
Description: SRT according to standard of care (66.6-72 grays will be delivered to the bed of prostate ,\~50.4 grays to the pelvis if needed)
Study NCT06305832 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SRT
Description: SRT according to standard of care (66.6-72 grays will be delivered to the bed of prostate ,\~50.4 grays to the pelvis if needed)
Study NCT05163899 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Release of filum terminale
Description: Surgery will be offered to section the filum terminale
Study NCT06471335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Extraction of microRNAs extracted from plasma (4 ml recovered as part of treatment)
Description: Comparison of these micro RNAs with the micro RNAs extracted from oral swabs (in Fetal Alcohol Spectrum Disorder group)
Study NCT06471335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Extraction of microRNAs extracted from bucal swabs (act added for research).
Description: Comparison of the microRNAs extracted from the oral swabs of the Fetal Alcohol Spectrum Disorder group with the microRNAs extracted from the oral swabs of the without Fetal Alcohol Spectrum Disorder group
Study NCT06471335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Extraction of microRNAs extracted from bucal swabs (act added for research).
Description: Comparison of the microRNAs extracted from the oral swabs of the Fetal Alcohol Spectrum Disorder group with the microRNAs extracted from the oral swabs of the without Fetal Alcohol Spectrum Disorder group
Study NCT06355700 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Liver biopsy
Description: The liver biopsy is ultrasound-guided and target the hepatic lesions. It is performed with 18G or 19G Menghini needle. A part of bioptic sample will be used for genomic analysis. An other part of sample will be cultured to create the organoid. The organoid's cultures will be integrated with the host gut microbiota (collected by a fecal sample) and peripheral blood mononuclear cells (from venous blood sample) and they will be used for research such as molecular analysis and pharmacological tests.
Study NCT04976101 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sinosuidal Galvanic Vestibular Stimulation
Description: stimulus will be given by applying paste electrodes over the mastoid processes and plugging the leads into a battery driven-stimulus box, which when activated by a switch, will provide a very low frequency (VLF) bipolar, ± 2 mA, 0.025 Hz oscillating current sGVS between the mastoids
Study NCT04976101 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: When assigned to placebo arm of the study, the patients will undergo same procedure as the treatment, only current will not be passed. (the device will still be placed on the mastoid process)
Study NCT06182956 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Noninvasive mechanical ventilation
Description: Noninvasive mechanical ventilation is a respiratory technique which allows the administration of positive inspiratory and expiratory airway pressures in order to ventilate the lungs.
Study NCT06182956 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nasal high-flow oxygen therapy
Description: Nasal high-flow is a respiratory technique which allows the administration of warmed and humidified air, associated with oxygen.
Study NCT06182956 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous positive airway pressure
Description: Continuous positive airway pressure is a respiratory technique which allows to maintain a constant positive airway pressure during inspiration and expiration.
Study NCT04812717 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CytoSorb device
Description: The CytoSorb device will be placed in the CPB circuit in half of the study population during their cardiac operation.
Study NCT05360797 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Outpatient
Description: After a 24-hour stay in the emergency department, the predictive factors of severity evaluation and the diagnosis of mild acute pancreatitis is confirmed, the patient is discharged and contacted daily for 4 consecutive days by the study investigators in each center.
Study NCT05360797 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical home care
Description: After a 24-hour stay in the emergency department, the predictive factors of severity evaluation and the diagnosis of mild acute pancreatitis is confirmed, the patient is discharged and contacted daily for 4 consecutive days by the medical home care department in each center.
Study NCT05360797 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hospitalization
Description: After a 24-hour stay in the emergency department, the predictive factors of severity evaluation and the diagnosis of mild acute pancreatitis is confirmed, the patient is hospitalized with usual treatment (PADI_1) in each center.
Study NCT05829226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LYT-200
Description: monoclonal antibody (mAb), targeting galectin-9 protein
Study NCT05829226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Bcl-2 inhibitor
Study NCT05829226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Hypomethylating agent
Study NCT05829226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: Hypomethylating agent
Study NCT05136924 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC-01 (varenicline 1.2mg/ml) nasal spray vs Placebo
Description: OC-01 nasal spray containing varenicline for treatment of signs and symptoms of DED. OC-01 (varenicline) nasal spray activates the trigeminal parasympathetic pathway and stimulates natural tear production to bathe the corneal nerve endings in a protective layer of tear film. In addition, OC-01 (varenicline) acts as a cholinergic agonist and may provide analgesia by activating the trigeminal parasympathetic pathway VS Placebo
Study NCT05136924 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (vehicle) nasal spray
Description: Placebo (vehicle) nasal spray
Study NCT04722419 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Probe meal
Description: The probe meal will be served in 112 Kcal portions (16 g white bread, 10 g cheese, 10 g jam, 3.25 g butter, and 50 mL orange juice) up to the level of maximal satiation.
Study NCT04722419 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Probe meal
Description: The probe meal will be served in 112 Kcal portions (16 g white bread, 10 g cheese, 10 g jam, 3.25 g butter, and 50 mL orange juice) up to the level of maximal satiation.
Study NCT06521931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PN20
Description: Three dose cohorts: 0.2, 0.5 and 0.75 mg/kg, subcutaneous injections, on Day 1 of chemotherapy cycle before the administration of chemotherapy drugs
Study NCT05562219 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QA108 granules
Description: Take the medication as required for 24 weeks
Study NCT05562219 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: QA108 granules placebo
Description: Take the medication as required for 24 weeks
Study NCT05550493 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy
Description: The cognitive behavioral therapy program consisted of eight interactive sessions, each requiring approximately 15 minutes to complete. Each ICBT session includes interactive multimedia modules (videos, pictures, and texts), the contents of which were based on the community reinforcement approach. The ICBT sessions covered the following topics: (1) introduction to digital therapeutics and CBT, (2) recognizing the triggers of craving, (3) coping with craving, (4) refusing skills/assertiveness, (5) problem-solving skills, (6) changing thoughts about drugs, (7) seemingly irrelevant decisions, and (8) HIV risks and prevention.
Study NCT05550493 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Counseling
Description: Counseling provided by social workers and psychotherapists on topics including work, family, stress management, and drug craving suppression.
Study NCT05550493 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Approach Bias Modification
Description: In an ApBM session, users were instructed to swipe upward (downward) when they saw portrait (landscape) format images. A shrinking (growing) animation comes after swiping upward (downward) to simulate the visual effect of moving away (moving towards). The images were related to methamphetamine usage (methamphetamine crystals, powders, and paraphernalia) or healthy lifestyles (wealth, sports, gourmet, family activities, etc.). Each ApBM session was composed of presenting each one of the healthy lifestyle (methamphetamine) cues 12 times in landscape (portrait) and once in portrait (landscape).
Study NCT05550493 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: The DTx application incorporated a game-based cognitive function training module for improving working memory. In this game, a matrix of squares is displayed at the center of the screen. Between 3 and 5 target symbols are randomly placed in the matrix and displayed for 2 seconds. Next, the symbols disappear, and the matrix randomly rotates. The participants were asked to click the correct locations of the target symbols within the prescribed time limit. The game becomes more difficult as the size of the matrix, the number of target symbols, and the complexity of the matrix rotation change at each level. Each cognitive function training session lasted between 3 and 5 minutes.
Study NCT05357001 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Connective tissue manipulation
Description: to remove muscle spasticity
Study NCT05357001 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stretching exercises
Description: to remove muscle spasticity
Study NCT04827680 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Venus Viva MD
Description: The Venus Viva™ MD fractional RF device has been shown in clinical studies to improve various skin conditions related to aging and alter collagen structures such as wrinkles, rhytids, and scars. Beginning with the Baseline visit (Visit 1), subjects will receive a total of 3 treatments approximately 3-5 weeks apart.
Study NCT06256380 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Cognitive-behavior therapy for adolescents with an eating disorder
Description: Psychotherapy
Study NCT06256380 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Family-based therapy for adolescents with an eating disorder
Description: Psychotherapy
Study NCT06016777 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided paraspinal block and patient-controlled intravenous analgesia pump
Description: Patients in this group will receive ultrasound-guided paraspinal block with 0.3% ropivacaine and 5mg dexamethasone in total of 20mL saline at T5 level on the operative side. Patients in all the groups will be treated with PCIA after surgery. PCIA with sufentanil will be applied to all participants, with background infusion at 1.8μg/hour, and total dosage \<5μg/hour.
Study NCT06016777 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided erector spinal block and patient-controlled intravenous analgesia pump
Description: Patients in this group will receive ultrasound-guided erector spinal block with 0.3% ropivacaine and 5mg dexamethasone in total of 20mL saline at T5 level on the operative side. Patients in all the groups will be treated with PCIA after surgery. PCIA with sufentanil will be applied to all participants, with background infusion at 1.8μg/hour, and total dosage \<5μg/hour.
Study NCT06016777 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient-controlled intravenous analgesia pump
Description: Patients in this group will not receive regional block. Patients in all the groups will be treated with PCIA after surgery. PCIA with sufentanil will be applied to all participants, with background infusion at 1.8μg/hour, and total dosage \<5μg/hour.
Study NCT06016777 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Patient-controlled intravenous analgesia pump
Description: Patients in this group will not receive regional block. Patients in all the groups will be treated with PCIA after surgery. PCIA with sufentanil will be applied to all participants, with background infusion at 1.8μg/hour, and total dosage \<5μg/hour.
Study NCT04956913 — intervention group
Intervention type: DEVICE
Intervention: Mac Grath
Description: Patients of this group were intubated using Mac Gath videolaryngoscope
Study NCT04956913 — intervention group
Intervention type: DEVICE
Intervention: Macintosh
Description: Patients of this group were intubated using the Macintosh Laryngoscope
Study NCT05631483 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DAISe
Description: Use of the DAISe Thrombectomy Device
Study NCT06288100 — intervention group
Intervention type: OTHER
Intervention: Observation
Description: 1. Measure changes in tibial slope after medial opening wedge High tibial osteotomy in Skeletally mature patient with unicompartmental osteoarthitis and genuvarus knee~2. Evaluate the effect of tibial slope angle change on the clinical outcome at 1 year .
Study NCT05573997 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Investigation of clinical profile, laboratory and novel echocardiographic imaging biomarkers
Description: Complete and comprehensive medical interview will be conducted in each eligible patient. In addition, patient's laboratory data will be recorded on admission and pre-discharge. Each patient will undergo a full echocardiographic examination with a specific protocol upon admission and pre-discharge. This will include among others 2-dimensional speckle-tracking analysis of all cardiac chambers, and non-invasive calculation of myocardial work indices of the left and right ventricle.
Study NCT05933382 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Corticosteroid Group
Description: Conventional exercise and corticosteroid injection
Study NCT05933382 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan Group
Description: Conventional exercise and mulligan mobilization
Study NCT04295278 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MicroKine Dx system
Description: Biomarker concentrations will be determined using the MicroKine Dx system and results will be compared to measurements taken using standard immunoassays.
Study NCT05819151 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: HbA1c Test
Description: HbA1c Test is required. No other interventions. The researchers will only take photos of the subjects' tongues, and ask them to fulfil a questionnaire.
Study NCT05201300 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam Besylate 6 mg/kg/hr
Description: Patients will receive remimazolam at 6 mg/kg/hr by continuous infusion until loss of consciousness.
Study NCT05201300 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam Besylate 12 mg/kg/hr
Description: Patients will receive remimazolam at 12 mg/kg/hr by continuous infusion until loss of consciousness.