AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04936529 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: OPT-821
Description: Vaccine injections must occur a minimum of 6 days apart. After the first four vaccine injections, vaccines can be administered up to two weeks earlier or later than indicated without representing a protocol violation.
Study NCT05341895 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Kinesiotape
Description: Taping
Study NCT05467566 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Transcranial direct current stimulation
Description: Exercise protocol + application of simulation of direct current stimulation for 30 minutes. The stimulator will be turned off after 30 seconds and the volunteers will not receive current for the rest of the session.
Study NCT05057884 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breathing training
Description: Slow nasal breathing with intermittent end-expiratory apnoea for 15 min twice per day over 12 weeks.
Study NCT05391295 — intervention group
Intervention type: OTHER
Intervention: Short daily questionnaire
Description: This study includes 1 survey that needs to be filled out by the patient on his/her phone daily during the course of corticosteroid treatment. The investigators will start the survey few days before the corticosteroid treatment and it will continue till the end of the treatment regime. The treatment regime is regular care and patient specific, but will approximately have a duration of 40 days. In case of prolonged treatment with steroids it is decided to have a limit for our study: either until 7 days after the end of corticosteroid treatment or a maximum of 60 days.
Study NCT05219006 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ketogenic dieting
Description: Atkins modified diet: 1.2-1.5 g/kg/day of protein with a ratio 1:1 (fat: carbohydrate + protein)
Study NCT05219006 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: healthy dieting
Description: Normocaloric diet established by a nutritionist. 1.2-1.5 g/kg/day of protein with a maximum contribution of 50 % carbohydrates of the total calorie intake eliminating industrialized food.
Study NCT05571852 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CogniFit's CCT Post COVID-19
Description: The computerized cognitive training (CCT) program is tailored to each person's specific cognitive strengths and weaknesses detected in the Cognitive Assessment Battery (CAB)™ PRO (CogniFit Inc., San Francisco, US; https://www.cognifit.com/cab) by a patented Individualized Training System™ (ITS) software.
Study NCT04796688 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine + Cyclophosphamide + CAR-NK-CD19 Cells
Description: fludarabine 30 mg/kg on day -5, -4, and -3; cyclophosphamide 300 mg/kg on day -5, -4, and -3; CAR-NK-CD19 Cells on day 0.
Study NCT03733028 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Intervention for Reducing Anger (MIRA)
Description: This is a mobile intervention that uses interpretation bias modification (IBM) techniques to reduce the hostile interpretation bias. Participants will be given a mobile device with the MIRA app and instructed to complete 5 treatment sessions each week for a period of 4 weeks. Each session takes approximately 10 minutes. The app also includes a Nightly Diary to track symptoms, a calendar to program session reminders, and a My Progress feature to track use and performance.
Study NCT03733028 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness Intervention
Description: This is a mobile intervention that uses the Mindful Breathing and Body Scan exercises from the Mindfulness Coach app. These audio-guided exercises take approximately 10 minutes each. Participants will be given a mobile device with the Mindfulness app and instructed to complete 5 exercises (i.e., Body Scan or Mindful Breathing) each week for a period of 4 weeks. The app also includes a Nightly Diary to track symptoms, a calendar to program reminders, and a My Progress feature to track use and performance.
Study NCT04713904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clormadinone 2 mg and Ethinyl estradiol 0.02 mg Test Product Coated Tablets
Description: Investigational Medicinal Product
Study NCT04713904 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clormadinone 2 mg and Ethinyl estradiol 0.02 mg Reference Product Coated Tablets
Description: Evafem 20 (Trademark)
Study NCT05084560 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AWZ1066S
Description: Candidate drug to treat lymphatic filariasis by targeting Wolbachia endosymbiont
Study NCT05084560 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06086860 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mulligan mobilization with dry needling.
Description: The duration of intervention will be 6 weeks, 2 sessions a week, a total of 12 sessions will be given to the study participants. Each session will last for 30 minutes.
Study NCT06086860 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mulligan mobilization without dry needling
Description: The duration of intervention will be 6 weeks, 2 sessions a week, a total of 12 sessions will be given to the study participants. Each session will last for 30 minutes.
Study NCT04124458 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency ablation
Description: In radiofrequency ablation arm, sensory brunch of occipital nerve will be burn with max allowable temperature: 42 degrees Celsius, real temperature: 41 degrees Celsius, power=65 volts, two cycles of 180 second.
Study NCT05923736 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Intima media thickness ultrasound
Description: EIM is a non-invasive ultrasound technique in which an ultrasound-generating probe is conventionally placed opposite the right primary carotid artery. By distinguishing between an inner layer, consisting of the intima and media, and the outer layer, the adventitia, the intima-media thickness can be assessed.
Study NCT05923736 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: hand ultrasound
Description: Performed by the rheumatologist, to quantify the number of synovial thickenings in B mode and the number of synovitis in Doppler mode. The presence or absence of joint erosions on the metacarpophalangeal (MCP), proximal interphalangeal (PPI) or distal interphalangeal (DIP) joints.
Study NCT05923736 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: EndoPAT™ 2000 system
Description: It's a measurement that detects endothelial dysfunction in coronary arteries using reactive hyperemia.This examination will be carried out in accordance with the manufacturer's instructions by the Rheumatology Department nurse. The patient lies down for the duration of the examination (20 minutes). A probe is placed on the index finger of each hand and a cuff on the left arm. Recording begins with a 5-minute baseline period (at rest), followed by a 5-minute period of arm occlusion, and ends with a 5-minute period of return to normal.
Study NCT05923736 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: X-ray absorptiometry (DXA)
Description: This X-ray examination will be carried out on the Hologic device and the analyses by APEX 4.0 software. Two-photon X-ray absorptiometry (DXA) is a method commonly used to measure bone mineral density. It is based on a scan of the body by an X-ray beam at 2 different energy levels, which enables 3 compartments to be individualized: mineral mass, lean mass and fat mass. This low-radiation method (less than a conventional chest X-ray) is regarded as a benchmark for accurate measurement of both bone mineral density and the various body compartments. The examination lasts 10 minutes and is carried out by the department's electroradiology manipulators
Study NCT05290454 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mNGS-guided treatment
Description: mNGS detect the causative microorganisms using appropriate lower respiratory tract (LRT) specimen. LRT specimen, such as endotracheal aspiration (ETA), bronchoalveolar lavage fluid (BALF), or protected specimen brush (PSB), will be obtained within 24 hours after the participants entering the ICU. Clinicians apply the definitive treatment based on mNGS results, as well as results of conventional microbiology diagnostic techniques.
Study NCT05479344 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A Brief Contextual Behavioural Intervention Based on Strengths, Meaning, Hope and Connection
Description: The intervention strategy combines acceptance and commitment therapy, contextual behavioral science, and positive psychology interventions (strengths, meaning, hope) in the form of a single intervention set (each topic is a single 90-minute intervention, four single intervention combinations).
Study NCT05479344 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: A Brief Contextual Behavioural Intervention Based on Strengths, Meaning, Hope and Connection
Description: The intervention strategy combines acceptance and commitment therapy, contextual behavioral science, and positive psychology interventions (strengths, meaning, hope) in the form of a single intervention set (each topic is a single 90-minute intervention, four single intervention combinations).
Study NCT04927767 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: denture adhesive
Description: Denture adhesive is a commercially available denture care product used to adhere a denture to the oral mucosa, in order to improve the retention and stability.
Study NCT04318691 — intervention group
Intervention type: BIOLOGICAL
Intervention: Blood sampling
Description: Blood sampling at baseline and at day-3 (10 ml, EDTA tube), test of NETs.
Study NCT04318691 — intervention group
Intervention type: PROCEDURE
Intervention: Bronchoalveolar lavage
Description: Bronchoalveolar lavage at admission to the ICU with analysis of cytological, bacteriological, viral and anatomopathological, and test of NETs.
Study NCT05958966 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-cigarette e-liquid self-administration
Description: Participant will self-administer an experimenter-provided e-cigarette.
Study NCT05061758 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3056480
Description: LY3056480 is an inhibitor of gamma-secretase
Study NCT05061758 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: LY3056480
Description: LY3056480 is an inhibitor of gamma-secretase
Study NCT06366685 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise and Psychological Intervention
Description: To address the symptoms and severity experienced by esophageal cancer patients after surgery, providing them with exercise or psychological interventions to improve their rehabilitation outcomes.
Study NCT05696652 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acute exercise
Description: 40 minute moderate intensity exercise bout on a treadmill. This is similar to a single session of cardiac rehabilitation.
Study NCT05696652 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Acute exercise
Description: 40 minute moderate intensity exercise bout on a treadmill. This is similar to a single session of cardiac rehabilitation.
Study NCT05696652 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiac rehabilitation
Description: 12 week program of standard clinical cardiac rehabilitation for patients with symptomatic heart failure. Patients undergo 3-times weekly sessions of monitored exercise for 12 weeks. This is the same cardiac rehabilitation patients would get as part of clinical care.
Study NCT05528159 — intervention group
Intervention type: PROCEDURE
Intervention: Intraabdominal CO2 insufllation
Description: Patients will receive intraabdominal CO2 insufflation and will be operated under trendelenburg position
Study NCT05039411 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PF2020-CELL (UC-MSCs) - Allogeneic Human Umbilical Cord Mesenchymal Stem Cells
Description: All patients will receive a total of 60 million PF2020-CELL (UC-MSCs) cells per treatment visit.
Study NCT06474598 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MTX228
Description: Tolimidone was developed as a treatment for gastric ulcers but did not advance beyond phase 2 clinical trials because of lack of efficacy. Subsequently, tolimidone has been identified as an activator of Lyn kinase and was considered as a treatment for type 2 diabetes as an insulin sensitizer because of Lyn's interaction with insulin signaling molecules. More recently, Lyn has been identified as a critical regulator of beta-cell mass, with genetic and biochemical inactivation of Lyn provoking beta-cell death in isolated human islets and precipitated diabetes in mice, and activation of Lyn stimulating beta-cell survival and beta-cell proliferation. These findings strongly suggest that small molecule activators of Lyn, such as Tolimidone, could represent new therapeutic options to promote beta-cell regeneration in type 1 diabete
Study NCT06474598 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DEXCOM G6
Description: To monitor participants blood glucose levels continuously
Study NCT05224232 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Access Socket
Description: During a period of 4 weeks, patients will live in their usual environment with the soft socket (Access-Socket)
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of tissue stiffness (N/m)
Description: Stiffness values will be measured with myotonPro on centers of coordination located along the myofascial chain
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of passive muscle tone (Hz)
Description: muscle tones will be measured with myotonPro on centers of coordination located along along the myofascial chain
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of creep of tissue
Description: creep of tissue will be measured with myotonPro on centers of coordination located along the myofascial chain
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of the range of shoulder joint motion
Description: The range of shoulder flexion, abduction, extension and external-internal rotation movements will be measured with a universal goniometer.
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of skin temperature
Description: measurements will be taken by the thermographic camera
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of pain
Description: Pain will be evaluated by visual analog scale (VAS)
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of pain pressure threshold
Description: Pain pressure threshold will be evaluated by a digital algometer
Study NCT05386641 — intervention group
Intervention type: OTHER
Intervention: measurement of grip strength
Description: The grip strength of both hand will be evaluated by hand-held dynamometer.
Study NCT04700228 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine Hydrochloride
Description: We are going to see the effects of dexmedetomidine as an adjunct to bupivacaine in caudal block. In first (control) group (group C) only bupivacaine will be given. Group BD1 patients will be given bupivacaine plus 1mcg/kg dexmedetomidine. Group BD2 patients will get bupivacaine plus 0.5mcg/kg dexmedetomidine. All the groups will be given a volume of 0.5ml/kg.
Study NCT05178030 — intervention group
Intervention type: OTHER
Intervention: vena punction
Description: Regular 3-12 monthly follow-up by CT-scan will be compared to results of ctDNA analysis. Blood for analysis of mutation in ctDNA will be collected at the same moment a CT-scan is performed
Study NCT04940897 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Use of CareSens ketone meter
Description: Use of CareSens ketone meter to identify blood ketone levels and delivery of fluid therapy to those patients at high risk of DKA
Study NCT05578638 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Aloe Vera rosemary tropical application
Description: 10 ml of the Aloe Vera rosemary spray will be rubbed two times per day during the skin care on the areas at risk for PIs, including the patient's sacrum area, hip areas and heels area. This action will continue for 10 days
Study NCT05578638 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: aloevera tropical application
Description: 10 ml of the Aloe Vera spray will be rubbed two times per day during the skin care on the areas at risk for PIs, including the patient's sacrum area, hip areas and heels area. This action will continue for 10 days
Study NCT05578638 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: rosemary tropicalapplication
Description: 10 ml of the rosemary spray will be rubbed two times per day during the skin care on the areas at risk for PIs, including the patient's sacrum area, hip areas and heels area. This action will continue for 10 days
Study NCT03854461 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalised dietary advice and educational material
Description: As within arm/group description
Study NCT03854461 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational material
Description: As within arm/group description
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Tablet
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: Tablet
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluorouracil
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leucovorin
Description: Infusion
Study NCT04488159 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immunoscore® assay
Description: Whole-slide tissue analysis of CD3+ and cytotoxic CD8+ T cells in the tumor and in the invasive margin
Study NCT04488159 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: Increasing stair walking exercise twice a week over 12 weeks total.
Study NCT06090266 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OR502
Description: IgG1 monoclonal antibody that binds specifically to the LILRB2 protein.
Study NCT06090266 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: IgG4 mAb that binds to PD-1 and blocks its interaction with PD-L1 and PD-L2.
Study NCT05539560 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Olfactory training with essential oils
Description: Olfactory training twice daily with essential oils from Urtegaarden Aps with scents of orange, lavender, clove and peppermint. The olfactory training is performed every morning and evening, by smelling each of the oils for 30 seconds.
Study NCT05539560 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Olfactory training with fragrance-free oils
Description: Olfactory training twice daily with fragrance-free oils from Urtegaarden Aps in the same four containers as the intervention group. The olfactory training is performed every morning and evening, by smelling each of the oils for 30 seconds.
Study NCT05215756 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous vagal nerve stimulation
Description: The tVNS device will be attached to the left concha of the ear to stimulate the auricular branch of the vagal nerve. Each stimulation will last for 2 minutes.
Study NCT05321381 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resilience In Stressful Events (RISE) peer support team
Description: Availability of peer support team to health care workers who experience stressful work-related events or situations
Study NCT06418633 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 60-minute walking test
Description: Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.
Study NCT06418633 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Static blood test
Description: 33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test
Study NCT06418633 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Post-effort blood test
Description: 33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.
Study NCT06418633 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiogram
Description: An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.
Study NCT06418633 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure monitoring
Description: Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.