AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05275530 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Dual Choice
Description: The investigators will send randomized participants a message via MyChart indicating the benefits of CRC screening, along with tailored information about FIT Kit and Colonoscopy screening. At the end of the message, participants will complete a survey asking them to indicate if they would like to be screened for CRC with either a FIT or Colonoscopy, or if they prefer no screening whatsoever. The investigators will then ask follow-up questions to better understand the reason patients made their respective choices.
Study NCT05447754 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined RAGT and TBT
Description: Combined RAGT and TBT: Participants will be treated with Lokomat for 40 minutes, twice a week for 5 weeks, and RAGT with a body weight support system and combined TBT for 40 minutes each session 3 times a week. During RAGT, 30-40% of each participant's body weight will be taken with the body weight support system. In patients without drop foot and knee instability in the sessions after the first session, the body weight will be reduced by 10% and progression will be achieved. The speed of the treadmill will be adjusted between 1.2-2.6 km/h and the maximum speed tolerated by the patient will be reached during the sessions. TBT exercises 3 times a week for 40 minutes (weight transfer to the paretic leg during sitting and standing, weight transfer during sitting and standing with or without an assistive device) will be personalized according to the patient. Progression of exercises will be provided by adding upper extremity and trunk activities in addition to exercises.
Study NCT05808010 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mononuclear cells
Description: 2 times gastric submucosal injection of mononuclear cells (10\^8) at 1 month interval
Study NCT05808010 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
Description: Orally delivered tablets for 7 months. Take it according to the instructions.
Study NCT05808010 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
Description: Orally delivered tablets for 7 months. Take it according to the instructions.
Study NCT06221787 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: 1565 nm non-ablative fractional laser combined with normal saline
Description: After 1565 nm non-ablative fractional laser treatment, patients with melasma were smeared with normal saline and to compared with those smeared with exosomes after laser treatment.
Study NCT06221787 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: microneedles combined with hUCMSC-Exos
Description: the hUCMSC-Exos were applied while rolling a microneedle roller and to compared with those used 1565 nm non-ablative fractional laser or PBASM combined with hUCMSC-Exos.
Study NCT06221787 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 1565 nm non-ablative fractional laser combined with hUCMSC-Exos
Description: After 1565 nm non-ablative fractional laser treatment, patients with melasma were smeared with hUCMSC-Exos and to compared with those smeared with normal saline after laser treatment.What's more,compared with those used microneedles or PBASM combined with hUCMSC-Exos.
Study NCT06221787 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PBASM combined with hUCMSC-Exos
Description: a plasma named Peninsula Blue Aurora Shumin Master (PBASM) rolling each area for 8-10 min before applying the hUCMSC-Exos in the entire face. And to compared with those used 1565 nm non-ablative fractional laser or microneedles combined with hUCMSC-Exos.
Study NCT06344260 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: human Neural Stem Cells (hNSC)
Description: The patient is placed on a regular operating room table with or without rigid head fixation. Procedure will be performed whether under general anesthesia or sedation and local anesthesia. Image guidance will be registered using the frameless stereotactic AxiEM system. Image guidance will be used to perform ventricular cannulation with the catheter passed over an electromagnetic-tipped stylet, which is recognized and tracked by the navigation system. The correct placement of the catheter is verified by the egress of CSF. Finally the electromagnetic stylet will be removed and a Rickam reservoir connect to ventricular catheter. Operative time will be about 30 minute. A post-operative CT scan will be obtained in all patients to confirm the catheter position.
Study NCT06344260 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Saline (Placebo)
Description: The patient is placed on a regular operating room table with or without rigid head fixation. Procedure will be performed whether under general anesthesia or sedation and local anesthesia. Image guidance will be registered using the frameless stereotactic AxiEM system. Image guidance will be used to perform ventricular cannulation with the catheter passed over an electromagnetic-tipped stylet, which is recognized and tracked by the navigation system. The correct placement of the catheter is verified by the egress of CSF. Finally the electromagnetic stylet will be removed and a Rickam reservoir connect to ventricular catheter. Operative time will be about 30 minute. A post-operative CT scan will be obtained in all patients to confirm the catheter position.
Study NCT05447754 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: balance exercises
Description: TBT
Study NCT05879848 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR
Description: virtual reality scenario synchronized with the uterine contractions
Study NCT06276725 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Writing Wrongs
Description: A repeated exposure writing practice targeting symptoms resulting from microaggressions experienced by minoritized students at predominantly White institutions.
Study NCT06067945 — intervention group
Intervention type: OTHER
Intervention: microleakage
Description: prevention of microleakage and secondary carries
Study NCT05339282 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic cholecystectomy
Description: Method of operation~1. Surgery was started under general anesthesia~2. A trocar of 10 mm was placed on the navel, 5 mm under the blade, and a 5 mm trocar was placed on the right upper abdomen.~3. Pneumoperitoneum was performed using CO2 gas in the abdominal cavity.~4. Dissection started from Calot's triangle, and the operation was performed by retrograde cholecystectomy.~5. The excised gallbladder was placed in a laparoscopic pocket and extracted through the umbilicus.~6. The trocar was removed, and the skin was sutured~On the 1st day after surgery, hematology, blood chemistry, urine, blood clotting, and chest x-rays were performed. (Inspection and treatment were performed according to the current clinical pathway of gallbladder surgery)
Study NCT05098509 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: RAD011
Description: Cannabidiol Oral Solution (containing synthetic cannabidiol)
Study NCT05098509 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo for RAD011
Study NCT06347939 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Mediastinal lymph nodes cryobiopsies
Description: EBUS Mediastinal lymph nodes cryobiopsies
Study NCT06054256 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group CBT-I
Description: The group-based intervention will consist of 6 weekly sessions (90-min, 5-8 pregnant women in each group). The treatment components aim to address the behavioural, cognitive and physiological factors perpetuating insomnia with the followings: psycho-education about sleep and sleep hygiene (e.g., psychoeducation about sleep during pregnancy and normal development and patterns of infant sleep, psychoeducation on ways of improving infant sleep, strategies to limit the development of unwanted sleep associations, etc.), stimulus control, sleep restriction, relaxation training, structured worry time, cognitive restructuring (targeting sleep-related dysfunctional cognitions), and relapse prevention.
Study NCT06054256 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: App-based CBT-I
Description: The smartphone app-based intervention will consist of 6 weekly sessions. The app-based intervention will involve a self-paced, fully automated digital programme with interactive components. The structure of the app involves six sequential modules (comparable to the six treatment sessions delivered in groups) with different elements to engage the users, such as animated videos, case vignettes, narration, quizzes, and homework assignment. Each module will be unlocked and released to the participants every week after the previous module has been completed. Personalised feedback will be provided by the app following the completion of sleep diary each week. Automated messages will be sent to the participants regularly via phone to remind them of implementing learned strategies after each module, as well as timely completing the treatment modules and sleep diaries.
Study NCT06054256 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Health related psychoeducation
Description: The control group will receive 6 sessions of group-based health-related psychoeducation, a format that has been adopted in the previous research, in order to provide the credibility of the intervention to the participants, and to control for the potential effects of attention and nonspecific components.
Study NCT05831254 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health education:Interactive group training
Description: 1. To introduce e-pulse software, which is a personal health record system, to show its use, to provide training materials such as video-brochures about e-pulse. This program will be done as interactive group training~2. Six modular interactive group training, each of which includes the steps of the European Health Literacy Scale of 90 minutes.
Study NCT05831254 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Health education: Individually training
Description: To introduce e-pulse software, which is a personal health record system, to provide training materials such as video-brochures about e-pulse. This education will be done individually.
Study NCT06530134 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Driving situation and video feedback
Description: At the end of the driving situation, 35 patients will be asked to express themselves and analyze 4 driving situations resulting from the course of the driving situation using video feedback.
Study NCT06530134 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Driving situation and usual recommendations (without video feedback)
Description: At the end of the driving situation, 35 patients will be asked to express themselves and analyze 4 driving situations resulting from the course of the driving situation without video feedback, according to the usual recommendations.~Comparison of responses to all questionnaires and interview grids sent before and after driving, to patients and professionals will determine whether video feedback promotes awareness of the difficulties of driving post-stroke patients.
Study NCT06422637 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Liquid Biopsy Early Screening
Description: An early screening model for lung cancer aids in identifying individuals with early-stage lung cancer. Those with positive indications of lung cancer will subsequently undergo confirmatory clinical assessments using Low-Dose Computed Tomography (LDCT) in sequence. Ultimately, a definitive diagnosis of lung cancer is established through surgical and pathological examination.
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCT461201 50 mg
Description: Oral capsule
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCT461201 100 mg
Description: Oral capsule
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCT461201 150 mg
Description: Oral capsule
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OCT461201 450 mg
Description: Oral capsule
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo capsule
Study NCT05688241 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Donor-derived ex-vivo expanded EBV Tscm CTL
Description: Cryopreserved cells will be thawed and infused at three time points. Dosing will be 2x10e6 EBV CTLs per kg of body weight. No prior lymphodepletion will be performed.
Study NCT06398925 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsule
Study NCT06303856 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Breathing Exercises
Description: Active breathing exercises aim to enhance the strength and flexibility of respiratory muscles through a series of exercises, improving breathing patterns and increasing respiratory efficiency. The following are common components of active breathing exercises: 1) Deep Breathing. 2) Chest Expansion. 3) Diaphragmatic Breathing. 4) Coughing Techniques. 5) Expiratory Resistance Training. 6) Gradual Increase in Activity.
Study NCT06258096 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LX2.3 Laser and LED Photobiomodulation System
Description: The LX2.3 Laser and LED Photobiomodulation system by THOR Photomedicine Ltd is a CE marked product and has a long track record of safety, usability, and effectiveness.
Study NCT06258096 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: LX2.3 Laser and LED Photobiomodulation System Sham-PBMT Setting
Description: The sham setting consists of light of the same colour (white light with a red filter), applied in the same way as in the experimental group.
Study NCT05211713 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Opp
Description: Opp is a universal mental health promoting mobile application for adolescents aged 13-25 years.
Study NCT05177432 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: QPOP
Description: QPOP will be used as a clinical decision support platform to identity suitable patient-specific drug combinations across a range of breast cancer patients, which are derived from drug sensitivity tests using patient-derived materials.
Study NCT04594525 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-Intensity Psychosocial Interventions through Telemental health
Description: Low-Intensity Psychosocial Interventions through Telemental health (Thinking healthy): The intervention will include six sessions. Each session may last to 45 min as a max, and it will be provided through telehealth. The first session will be an introduction, while the other five sessions will be covering the period from the second pregnancy trimester to the first year of the infant's life.
Study NCT05270954 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Betuvax-CoV-2
Description: Vaccine: Betuvax-CoV-2 intramuscular injection solution (0.5 ml)
Study NCT05270954 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo: a 0.9% NaCl intramuscular injection solution (0.5 ml)
Study NCT06189222 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality glasses
Description: The population of the study consisted of children who were aged between 7- 12 and were on treatment using an intravenous catheter in the pediatric emergency unit of a state hospital in Turkey.Participants were divided into two groups, namely experimental and control groups, by using simple randomization software. The design and implementation of the study were based on the principles in the CONSORT list (Consolidated Standards of Reporting Studies). Descriptive data form for children,this form was prepared to collect information about the children included in the sample. It consists of seven questions on children's sociodemographic characteristics and previous intravenous catheter insertion experience.The Children's Emotional Manifestation Scale (CEMS), this scale was developed by Li \& Lopez (2005) to measure children's emotional responses during stressful medical procedures. The VR glasses we used in our study were connected to a mobile phone.
Study NCT05584865 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital occluar prosthesis
Description: Each patient will receive the full digital fabricated ocular prosthesis. DICOM data from the Computerized Tomography (CT) will be imported into Materializes Interactive Medical Image Control System (MIMICS) software++++ tool for visualizing and segmenting medical images (such as CT and MRI)
Study NCT05584865 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional occluar prosthesis
Description: An accurate impression of the patient's eye socket will be obtained to prepare a suitable wax mod. The wax model will be flasked and processed into heat cured acrylic resin of the same colour of the sclera of the other healthy eye of the patient
Study NCT05696912 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Ex-vivo approach concerning 25 patients
Description: Ex-vivo approach concerning 25 patients with blood sample in PAXgene tubes or skin biopsy and RNA-Seq analysis
Study NCT05696912 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: In-vitro approach concerning 25 patients
Description: In-vitro approach concerning 25 patients without specific samples needed for analysis in minigene or luciferase assay
Study NCT04822389 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Telerehablitation using heart rate monitor
Description: Eligible participants will undergo 12 weeks of physical exercise using a heart rate monitor and internet platform at home. The participants will regularly (minimum once per week) upload the exercise data from the heart rate monitor into the internet platform. An exercise telerehabilitation session consists of the warm-up phase, aerobic phase (30 - 50 minutes gradually increasing exercise duration; heart rate zone based on baseline cardiopulmonary exercise test) and cool-down phase. The exercise training period is set to 3 times a week for 12 weeks. Study participants will receive user guides developed by research team with detailed instructions regarding equipment set-up, training protocol, and contact information. Also, participants will receive weekly phone calls from week 0 to week 12 to monitor adverse events, encourage compliance and adherence to the study protocol, address any subject questions or concerns, and collect information regarding participants' current symptomatology.
Study NCT04718883 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD19-targeted Chimeric Antigen Receptor (CAR) T Cells
Description: JWCAR029 will be administered at dose level: 1 x 10\^8 CAR+T cells
Study NCT05465850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Modified USPHS criteria
Description: It assess the restorations with visual inspection using a mirror and explorer. It includes Marginal integrity, shade matching, retention, marginal discoloration, gingival inflammation, and recurrent caries.
Study NCT05465850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Modified USPHS criteria
Description: It assess the restorations with visual inspection using a mirror and explorer. It includes Marginal integrity, shade matching, retention, marginal discoloration, gingival inflammation, and recurrent caries.
Study NCT05359575 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio kit
Description: MP3 audio files for each of 6 steps of c-collar application (totaling 1 minute, 19 seconds) and instructional flashcard with seven pictures corresponding to each of the 6 steps of c-collar application
Study NCT05359575 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Instructional flashcard (version 1)
Description: Single page with 7 pictures corresponding to each of the 6 steps of cervical collar (c-collar) application.
Study NCT05359575 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In-person training
Description: 10 minute of an LFR spinal immobilization course (extracted from the current LFR Level 1 trauma course).
Study NCT05359575 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Instructional flashcard (version 2)
Description: Single page with 7 pictures corresponding to each of the 6 steps of cervical collar (c-collar) application edited for clarity based on initial pilot feedback.
Study NCT05454826 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 1st group (n=15) relaxation exercises, 2nd group (n=15) relaxation exercises+cold compression. The exercise program will be applied for 6 weeks, 3 days a week \* 45 minutes. Relaxation exercises will be applied to the patients 3 days a week using web-based methods (Zoom).
Study NCT06528522 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical Measurements and Saliva Sample Collection
Description: Saliva samples will be collected from all participants, and comprehensive clinical parameters will be meticulously documented. The Plaque Index (PI) and Gingival Index (GI) will be measured at four sites per tooth. Full-mouth probing depth (PD) and clinical attachment level (CAL) will be recorded in detail for each tooth at six sites. The percentage of bleeding areas will be assessed within 20 seconds post-probing using a binary scoring system to indicate presence or absence. All clinical parameters will be recorded by a calibrated periodontologist utilizing manual probing techniques.~Following collection, saliva samples will be stored at -80°C until subsequent analysis. Concentrations of IL-39, IL-41, IL-1β, and TNF-α in the saliva samples will be quantified using specific enzyme-linked immunosorbent assay (ELISA) kits.
Study NCT05454826 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Application
Description: 1st group (n=15) relaxation exercises, 2nd group (n=15) relaxation exercises+cold compression. The exercise program will be applied for 6 weeks, 3 days a week \* 45 minutes. Relaxation exercises will be applied to the patients 3 days a week using web-based methods (Zoom).
Study NCT05071885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: games based exercise
Description: Range of motion and strengthening exercises