AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05760092 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Institutional standard treatment for xerostomia and Long Covid
Description: (Medical follow-up at the general outpatient clinic for prescription and control of medications, underlying diseases, clinical status and routine short, medium and long-term care follow-up, standard guidelines for the use of aerobic physical activity in those who do not have contraindications, stretching exercises, ergonomics, home adaptation to maximize functionality and energy savings, emotional cognitive support psychotherapy, socio-educational measures, sleep hygiene, Nutritional follow-up and monitoring, dentistry follow-up at the University's odontological team, guidance on proper oral hygiene, use of low-sugar diets, daily topical use of fluoride and antimicrobial mouthwash to prevent dental caries, oral hydration, guidance on avoiding cigarette use or intake of caffeine-containing beverages . When necessary, measures such as oral lubricants, artificial saliva, measures to prevent aspirations, as well as the careful use of liquids during meals, can be instituted ) +
Study NCT05760092 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Photobiomodulation Therapy
Description: Application of Red LED in the 3 pairs of major salivary glands (parotid, submandibular and sublingual) extraorally, transcutaneously, for 36 seconds, twice a week for 06 weeks.
Study NCT05760092 — intervention group
Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Photobiomodulation Therapy
Description: All parameters as the number of points, dose and place of application of the PBM will be the same as described in the item PBM therapy Intervention Group, however in the placebo PBM equipment will be turned off. The device activation noise will be recorded and used to mimic the irradiation.
Study NCT04951310 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Philly Vax Sweepstakes
Description: The Philly Vax Sweepstakes is a citywide sweepstakes designed to motivate Philadelphians to get vaccinated against COVID-19. A total of 36 vaccinated Philadelphians will win among three cash prize packages, distributed from the total cash pool. These 36 will be chosen over three drawings, with 12 residents chosen in each drawing.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Changes to the electronic health record (EHR)
Description: EHR changes will include minor changes to prescription fields to make it easier for clinicians to order wait and see antibiotics to be filled only if the child worsens or does not improve rather than antibiotics to take immediately.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Changes to the electronic health record (EHR)
Description: EHR changes will include minor changes to prescription fields to make it easier for clinicians to order wait and see antibiotics to be filled only if the child worsens or does not improve rather than antibiotics to take immediately.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Individualized audit and feedback reporting for clinicians
Description: Automated audit and feedback reports detailing participating clinicians' antibiotic prescribing habits for AOM both individually and in comparison to their peers will be shared with clinicians on a quarterly basis throughout the intervention period.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Individualized audit and feedback reporting for clinicians
Description: Automated audit and feedback reports detailing participating clinicians' antibiotic prescribing habits for AOM both individually and in comparison to their peers will be shared with clinicians on a quarterly basis throughout the intervention period.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Clinician education sessions
Description: Virtual education sessions will be held for clinicians to learn more about national guidelines for antibiotic prescribing for AOM, etc. The sessions will be recorded and distributed to clinicians who were unable to attend. Attendance of these sessions will apply toward continuing medical education credits for participants.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinician education sessions
Description: Virtual education sessions will be held for clinicians to learn more about national guidelines for antibiotic prescribing for AOM, etc. The sessions will be recorded and distributed to clinicians who were unable to attend. Attendance of these sessions will apply toward continuing medical education credits for participants.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Use of a shared decision-making (SDM) aide
Description: A previously validated SDM aide for AOM will be used by clinicians during visits with children with AOM. The aide will be available online and in paper form.
Study NCT06034080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Shared decision-making (SDM) education
Description: Clinicians will receive education on SDM and how to use the aid via virtual, recorded sessions.
Study NCT05069662 — intervention group
Intervention type: OTHER
Intervention: Directive Interview
Description: One directive interview conducted by telephone
Study NCT05222568 — intervention group
Intervention type: BEHAVIORAL
Intervention: Lateral positioning
Description: After the DLT intubation, the patient is placed in lateral decubitus position
Study NCT04856917 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imsidolimab
Description: Humanized Monoclonal Antibody
Study NCT05222568 — intervention group
Intervention type: DEVICE
Intervention: Cuff pressure measurement
Description: The pressure of the bronchial cuff should be measured with cuff-manometer in supine position, and then measurement should be repeated after lateral positioning
Study NCT05080582 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mother-Scented Simulated Hand
Description: Preterm neonates wrapped with a warm Mother-Scented Simulated Hand during the invasive procedures
Study NCT05080582 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: NICU Standard Care
Description: Neonates were placed in a side-lying position, while their extremities were flexed close to the body and wrapped with rolled sheets or towels to simulate the intrauterine posture.
Study NCT03051451 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: combination metformin hydrochloride/ fluoxetine 500/20 mg
Description: Group A will receive metformin 1000 mg and 40 mg of fluoxetine; after the increment phase.~All treatment groups will receive, in addition to the intervention, recommendations of a diet based on a hyper protein, hypo caloric and low carbohydrate diet as well as an exercise routine according to age and physical condition
Study NCT04866134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ERAS-007
Description: ERAS-007 will be administered orally as specified in Arm description.
Study NCT04856917 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT04866134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ERAS-601
Description: ERAS-601 will be administered orally as specified in Arm description.
Study NCT03945500 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Investigational Mobile Medical Software Application & IT Dashboard Application, FDA approved Bluetooth spirometer, FDA approved pulse oximeter
Description: Standardized Home Spirometry (SHS) Method consists of an Investigational Mobile Medical Application embedded into an Android Tablet, an FDA approved Bluetooth spirometer, an FDA approved pulse oximeter. HIPAA compliant data will be sent to an Investigational IT dashboard maintained at the Central Monitoring Institute Server.~Volunteers will train in-center or remotely \& perform baseline testing with the SHS method along with a baseline laboratory-based spirometry test (if practicable).~Pre-Surveillance Phase: Daily home spirometry method testing for 4 to 10 weeks to enable normal range calibration.~Surveillance Phase: At least weekly home spirometry method testing for 2-10 months of participation. Volunteers will maintain a test log during study team directed SHS software pathway functionality testing.
Study NCT05107310 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pedicle screws insertion by free hand technique
Description: Spinal deformity correction. Pedicle screws are inserted using free hand technique with the help of intraoperative fluoroscopy if needed.
Study NCT05107310 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pedicle screws insertion using ARSN
Description: Spinal deformity correction. Pedicle screws are inserted using augmented reality surgical navigation (ARSN) with the ClarifEye navigation system and the Philips Allura 2D/3D imaging system.
Study NCT05107310 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pedicle screws insertion using IRSN
Description: Spinal deformity correction. Pedicle screws are inserted using infra-red surgical navigation (IRSN) with the Brainlab Curve 1.2 navigation system combined with the Medtronic O-arm 2D/3D imaging system.
Study NCT05362032 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo transrectal MRI-targeted biopsy
Study NCT05362032 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endorectal Magnetic Resonance Imaging
Description: Endorectal MRI
Study NCT05114941 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: immunosorbent column
Description: Immunoadsorption treatment regimen: the treatment is performed once every 1-3 days, at least 5 times, and the amount of regenerated plasma for each treatment is 1 to 3 times the plasma volume. The immunosorbent column adopts the protein A immunosorbent column.
Study NCT05114941 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: intravenous immunoglobulin
Description: Intravenous immunoglobulin treatment regimen: intravenous immunoglobulin therapy, 400mg/kg/d, once a day, for at least 5 consecutive days.
Study NCT05166122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Artificial Intelligence
Description: Introduction of digitized system with an AI tool to detect and intrepret the severity of diabetic retinopathy and presence of diabetic macular edema in screening for diabetes patients
Study NCT05491707 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music
Description: Patients will choose a genre of music from the following list; pop, gospel, classical, jazz, and soul, at the preoperative visit. This will be played on disposable ear phones at a self-selected volume for the duration of the surgical procedure.
Study NCT06532201 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Su jok seed therapy
Description: Su Jok will be applied to the reflection points on the hand based on the painful area of the individual. The painful areas will be determined with the applicator and black pepper seeds will be placed on these areas. Circular massage will be applied to the areas where the seeds are located for 30 minutes.
Study NCT05053555 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high dose rate brachytherapy
Description: diagnostic workup, staging, and treatment per the institution standard of care
Study NCT05053555 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high dose rate brachytherapy
Description: reviewing historical patients who meet the above criteria for group A but did not receive HDRBT between 01/01/2000 and 1/01/2021
Study NCT06156488 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Maxillary sinus floor augmentation
Description: Maxillary sinus floor augmentation through a lateral window grafted with anorganic bovine bone + polynucleotides and hyaluronic acid
Study NCT06156488 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary sinus floor augmentation
Description: Maxillary sinus floor augmentation through a lateral window grafted with anorganic bovine bone
Study NCT06633133 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Virtual ileostomy
Description: A pre-stage ileostomy, anchored under the abdominal wall by a vascular sling or rubber tape through the mesenteric window, is delivered to the outside of the abdomen, where the VI is pulled through the abdominal wall.
Study NCT06375460 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Focused App Prompt
Description: Prompts are designed to develop knowledge and self-efficacy in diabetes-related health behaviors (capability). The paired glycemic and behavior data will provide the opportunity to reflect and to plan diet or exercise for the following day (self-reflective motivation).
Study NCT05951816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m.
Description: Peptide p5+14 is a pan-amyloid reactive, synthetic 45 L-amino acid polypeptide with a net +12 positive charge that can bind two major components of all extracellular amyloid deposits: (i) hypersulfated heparan sulfate glycosaminoglycans (proteoglycans) and (ii) amyloid fibrils. The polypeptide, labeled with iodine-124, has been shown (study AMY1001) to bind amyloid in all organs including the heart. This study will evaluate a Tc-99m-labeled version of the peptide for gamma imaging.
Study NCT05951816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 99mTc-Pyrophosphate and 99mtc-p5+14 - an Amyloid Reactive Peptide Labeled With Technetium-99m.
Description: 99mTc-PYP is an FDA-approved, commercially available bone-seeking radiotracer used routinely in nuclear medicine. 99mTC-PYP imaging is used clinically for the diagnosis of cardiac ATTR amyloidosis.
Study NCT06375460 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: No App Prompt
Description: No app prompts are designed to assess whether health behaviors are affected without being prompted to reflect and change those behaviors related to glycemic control.
Study NCT05155969 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine
Description: esketamine (0.3 mg/kg in 100 ml normal saline) is intravenously infused 40 minutes before anesthesia induction
Study NCT05155969 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Normal saline will be administrated intravenously at the dural opening, with a total dose of 0.5 ml/kg and continual infusion for 40 minutes.
Study NCT04765020 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: moderate to high-intensity exercise
Description: Four parts:~1. Initial consultation with recommendations for general physical activity, brochure with exercise recommendations~2. Once per week multi-modal group-based exercise (endurance, strength, mobility, coordination)~3. Once per week supervised multi-modal individual training session (endurance, strength, mobility, coordination). Intensity: 60-80% of max. HR~4. Activity trackers with individual movement goals that will be adjusted every two weeks
Study NCT05351203 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: caudal block
Description: . Sacral horns will be palpated and sacral hiatus and epidural area will be determined at S4-S5 level through the ultrasound,. Short axis (transverse) is used first to identify the two sacral cornua as two hyperechoic reverse U-shaped structure Frog sign and the sacrococcygeal ligament in between and epidural space beneath. An 18-gauge epidural needle (length 90 mm) is used for direct puncture of sacrococcygeal membrane out of plane then the probe is rotated to long axis (longitudinal) and the needle is seen in plane in the epidural space. Injection of 30 ml 0.125% bupivacaine will expand the epidural space.
Study NCT05351203 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae block
Description: ● The patient will be in the prone position, after skin sterilization, ESP block will be performed at the level of L3. a curvilinear high-frequency ultrasound transducer (Siemens acuson x300 3-5 MHz ultrasound) will be placed sagittal 3 cm lateral to L3 spinous process where a hyperechoic shadow of the transverse process (TP) and erector spinae will be defined. A 22-gauge spinal needle will be inserted in cranial to caudal direction toward TP in plane to the ultrasound transducer until the needle touches the TP crossing the whole muscles. The location of the needle tip will be confirmed by visible normal saline solution separating erector spinae muscle off the bony shadow of the TP on ultrasound imaging. After confirming the needle site, 30 mL of 0.25% bupivacaine will be injected. The procedure will be repeated following the same steps on the other side.
Study NCT04991740 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-78306358
Description: JNJ-78306358 will be administered.
Study NCT04890483 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation
Description: tDCS: the energy of the anode (transcranial current stimulation) will have as its source a battery-powered DC generator and will be exerted by two electrodes measuring 5x7cm and attached to the head. The electrodes will be located of the primary motor cortex. The electrode with positive charge (anode) will be positioned at contralateral to the dominant limb and the negative charged electrode will be positioned in the supraorbital region ipsilateral to the dominant limb. The active current of direct transcranial stimulation will be applied with the intensity of electric current of 2mA and density of 0.057 mA/cm2 with duration of 20 minutes. During the session, patients will remain seated. Number of sessions: five times, once per day.
Study NCT06566053 — intervention group
Intervention type: OTHER
Intervention: Observation
Description: Observation
Study NCT05260658 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CFTX-1554
Description: CFTX-1554 is a new chemical entity that binds to the angiotensin II type 2 receptor (AT2R).
Study NCT05260658 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: CFTX-1554 matching placebo
Study NCT06460727 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: task oriented exercise training on dynamic surface
Description: Following exercises will be performed in this group: Make the child bounce on swiss ball, reaching the toy with both hand kept over the head on platform swing, high sitting on swiss ball throwing ball with both hands, reaching the toy with one hand shifting the wait towards reaching side.
Study NCT06460727 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: task oriented exercise training on static surface
Description: The children in this group will receive following TOET: Sit to stand from various cjair heights , standing and reaching indifferent directions for an object, Stepping forwards, backwards, and sideways onto blocks of various heights, walking forward , backward and sideways, Walking up and down stairs
Study NCT05226962 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ketone monoester
Description: A commercial liquid supplement ingested in a dose intended to provide \~0.35 g of ketone monoester per kg body mass of the participant
Study NCT04718727 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral Placebo tablets one-hour preoperatively
Study NCT04718727 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5 mg Olanzapine Tablets
Description: oral 5 mg Olanzapine tablets one-hour preoperatively
Study NCT04718727 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 10 mg Olanzapine Tablets
Description: oral 10 mg Olanzapine tablets one-hour preoperatively
Study NCT06568848 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: EKKO therapy
Description: In this group 6 particepents will be included .the interventions will be given for 10 seconds on each finger tips . the session will be 30 mins. 4 to 5 sessions per week
Study NCT03051451 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: combination metformin hydrochloride/ fluoxetine 1000/20mg
Description: Group B will receive metformin 1700 mg and 40 mg of fluoxetine; after the increment phase.~All treatment groups will receive, in addition to the intervention, recommendations of a diet based on a hyper protein, hypo caloric and low carbohydrate diet as well as an exercise routine according to age and physical condition
Study NCT03051451 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Group C will receive placebo oral tablet; All treatment groups will receive, in addition to the intervention, recommendations of a diet based on a hyper protein, hypo caloric and low carbohydrate diet as well as an exercise routine according to age and physical condition
Study NCT06568848 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Conservative Treatment
Description: In this group 6 participants will be included .: Conservative treatment, which includes ROM isometric exercises (20 repetitions per limb), stretching exercises (10 seconds per limb with 3 repetitions), balance training (standing without belts for 20 minutes), and gait training (walking with a frame). The session will be 30 mins
Study NCT06193044 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine/Valsartan
Description: Amlodipine 10 mg \&valsartan 160 mg
Study NCT06193044 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amlodipine/Valsartan
Description: Amlodipine 10 mg \&valsartan 160 mg
Study NCT06193044 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine 10 mg &valsartan 160 mg (Exforge)
Description: Amlodipine 10 mg \&valsartan 160 mg
Study NCT06193044 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amlodipine 10 mg &valsartan 160 mg (Exforge)
Description: Amlodipine 10 mg \&valsartan 160 mg