AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06668974 — intervention group
Intervention type: OTHER
Intervention: Mendelian Randomization
Description: This study utilizes a bidirectional Mendelian randomization approach to analyze genetic data from individuals with allergic rhinitis and asthma. No active intervention is applied; genetic variants serve as instrumental variables to assess causal associations between the conditions.
Study NCT04348604 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Customized Adherence Enhancement for Adolescents and Young Adults (CAE-AYA)
Description: Customized Adherence Enhancement for Adolescents and Young Adults (CAE-AYA): CAE-AYA participants will have 4 core in-person sessions (45-60 minutes each) spaced about 1 week apart over a period of approximately 4 weeks and one booster in-person session approximately 4 weeks after completion of the 4 core sessions (total of up to 5 in-person sessions spaced out over 8 weeks). There will be one follow-up phone call with a study interventionist, approximately 6 weeks post-baseline (timed half-way between completion of the core sessions and the booster session). All AYAs assigned to the CAE-AYA arm will receive all 4 modules (Psychoeducation on BD Medications; Communication with Providers \& Caregivers; Medication Routines; and Targeting Risky Behavior via Modified Motivational Enhancement Therapy (MET)), with the content within each module being customized to developmental stage and behavioral experience.
Study NCT04348604 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment as Usual (ETAU)
Description: Enhanced Treatment as Usual (ETAU): ETAU will consist of usual clinical care with prescribing clinicians and therapists, augmented by written materials specific to BD for AYAs and 6 follow-up telephone calls to briefly review the materials and be available for questions by social workers with mental health experience and at least some experience in working with AYA with BD. In order to ensure that there is not treatment contamination, different trained interventionists will be used for CAE and eTAU. Therapists will briefly review the materials and be available for questions during the phone calls. Materials will cover general self-management in BD. The calls will be relatively brief (maximum of 20-30 minutes).
Study NCT06670690 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atenolol 50 MG
Description: patients will be premedicated with atenolol (50mg)
Study NCT06670690 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propranolol Pill
Description: patients will be premedicated with propranolol (10mg)
Study NCT06670690 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ivabradine
Description: patients will be premedicated with Ivabradine (5mg)
Study NCT05245864 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: blood flow restriction
Description: Blood flow to the legs will be mostly restricted temporarily during physical therapy exercises for the initial several weeks of physical therapy.
Study NCT05245864 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: physical therapy standard of care
Description: the current standard of care after surgery for ACL repair.
Study NCT06293235 — intervention group
Intervention type: OTHER
Intervention: Lifestyle and metabolic indicators
Description: Socio-demographics, health history, behavioural characteristics, environmental exposures, anthropometric measurements, body fat composition, metabolic and stress biomarkers, semen physical and molecular characteristics.
Study NCT04928235 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Thermal Imaging as Diagnostic Adjunct
Description: Thermal images of the participants lower extremities will be taken and skin surface temperature values will be provided to the healthcare provider for review during the emergency department encounter.
Study NCT05522517 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cosentyx
Description: Cosentyx injection will be administered subcutaneously.
Study NCT05522517 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Candin
Description: Candin will be administered interadermally along with NaCl solution.
Study NCT05277922 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C21
Description: C21 in ascending doses of 15, 50, 150, 500 and 1000 µg
Study NCT06630871 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Distitamab Vedotin in combination with Tislelizumab
Description: On the day after the initial TURBt procedure, use trastuzumab (200mg)+ Distitamab Vedotin (120mg \[≤ 60Kg\] or 2.0mg/Kg \[>60Kg\]) every 3 weeks (Q3W). Simultaneously arrange for the patient to complete a second TURBt within 6 weeks, and continue to use 3 courses of Trastuzumab+Vediximab (Q3W) after surgery until the endpoint of 3-year follow-up
Study NCT06633640 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Conventional flap with algae-based substitute (AlgOss) combined with collagen membrane.
Description: The graft material will be prepared following the manufacturer instruction, transferred into a sterile cup than the mixture is condensed without overfilling in the intrabony defect to the level of the surrounding bony walls. The filled site will be than covered with collagen membrane.
Study NCT03738410 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile Health Messaging application
Description: Mobile messaging sent to participants over a 12-month period.
Study NCT03738410 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Treatment
Description: Standard of care (SOC) is defined as the usual care a licensed health care provider would give patients to treat HIV/AIDS. SOC associated procedures and policies may vary across clinical settings.
Study NCT05277922 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Nitroprusside
Description: Ascending doses of 4, 8 and 16 µg
Study NCT05992649 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical therapy
Description: Aquatic physiotherapy in warm water
Study NCT03738410 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care Treatment
Description: Standard of care (SOC) is defined as the usual care a licensed health care provider would give patients to treat HIV/AIDS. SOC associated procedures and policies may vary across clinical settings.
Study NCT04528303 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Whole genome sequencing
Description: Genomic sequencing and molecular diagnostic results
Study NCT04528303 — intervention group
Intervention type: GENETIC
Group type: ACTIVE_COMPARATOR
Intervention: Whole exome sequencing
Description: Genomic sequencing and molecular diagnostic results
Study NCT06290700 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neonatal Care education
Description: Participants who met the study inclusion criteria were provided with information about the purpose and conduct of the study, and their consent to participate was then obtained. The interviews were conducted in the breastfeeding room at the Uşak Dikilitaş Family Health Centre. The data were collected between November 2022 and November 2023. The Family Health Centre has two vaccination rooms, two antenatal care rooms, two observation rooms, and two breastfeeding rooms. Each pregnant woman was individually enrolled in an education session held in the breastfeeding room. The breastfeeding room was approximately 20 m², which was considered standard for accommodating training for an average of three pregnant women. The breastfeeding room was quiet, had a suitable temperature, and was located on the first floor in the middle of the corridor.
Study NCT05297071 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Orascopic HDL 3.0 Loupes
Description: The loupes will be used during the surgical procedure on half of the subjects. The other half will be performed with a microscope.
Study NCT05297071 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Semorr DOM3000D Operation Microscope
Description: The microscope will be used during the surgical procedure on half of the subjects. The other half will be performed with loupes.
Study NCT04722965 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fistulotomy with marsupialization
Description: A probe is placed in the fistula tract and it's laid open over that probe. The tract is curretted. Wound edges are sutured to the bottom of the fistula using interrupted sutures of vicryl 3-0 completing the marsupialization.
Study NCT04722965 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fistulotomy with open wound
Description: A probe is placed in the fistula tract and it's laid open over that probe. The tract is curretted. The wound is left open.
Study NCT06315218 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iTHRIVE 365 HIV care intervention
Description: iTHRIVE 365 is a multicomponent intervention that combines mHealth features and institutional to support community priorities identified in formative CBPR. In line with best-practices for trials of intervention principles (TIPs) with mHealth interventions, iTHRIVE 365 deploys intervention elements that serve to accomplish intervention strategies. iTHRIVE 365 intervention strategies are to promote: 1)Health knowledge and motivation; 2)Social support coping; 3)Access to culturally-affirming healthcare; and 4)Housing and other economic resources. iTHRIVE 365 pursues these strategies via these intervention elements: 1)Weekly HIV and psychological health information and motivation content and daily health notifications; 2)Online moderated forums, interpersonal chats, and community calendars; 3)Linkage to biopsychosocial healthcare via THRIVE SS's network of Black SGLM-affirming providers; and 4)Housing and economic resources through THRIVE SS's direct support and referral network.
Study NCT02315157 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bendamustine
Description: Given IV
Study NCT05684965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XTX301
Description: XTX301 monotherapy
Study NCT04788667 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: A health education programme using a telerehabilitation platform
Description: All patients enrolled in the study will receive information through the tele rehabilitation platform, although the experimental group will have specific training/education whereas the control group will only receive some general recommendations as control/sham
Study NCT04788667 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A health education programme using a telerehabilitation platform
Description: All patients enrolled in the study will receive information through the tele rehabilitation platform, although the experimental group will have specific training/education whereas the control group will only receive some general recommendations as control/sham
Study NCT05680025 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical exercise intervention
Description: The intervention group will have access to training videos through social networks (WhatsApp and YouTube) and infographics. The mobile phone of each of the participants will allow send dates of workshops, link for videos, messages reminding to perform exercise routines.~The training plan will be designed so the participants will achieve being physically active at the end of 6 months of intervention. Training will be planned to gradually, through 3 levels, increase the duration and intensity of exercises; they will have an important component of aerobic exercises and others for muscular strength. Each level of training will last two months; at each level the participants will be given 4 specific trainings and will be asked to perform two per week at level 1 and 2; and at the 3 level, 3 trainings per week.~The strategy for promoting physical exercise is based on the social cognitive theory, in which the bases of the transtheoretical model are found.
Study NCT05680025 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Workshops
Description: Six workshops to promote the performance of physical activity. The workshops will be held with groups of 15 participants. During them, the work will be to promote motivation to perform physical exercise, sharing information about the health benefits, benefits for control of the disease, together creating planning of measurable, realistic goals; reinforcing behavior when the desired advances are made, monitoring progress (using a monthly self-report of exercise performed). The participants will be motivated and congratulated each time for goals reached, self-sufficiency will be reinforced as well as greater evaluation of the advantages of performing exercise against the barriers or negative aspects perceived by the participants. These activities will be performed according to the level of exercise performed by the individuals (stage of change).
Study NCT04837482 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGN-190584
Description: Topical eyedrop
Study NCT04837482 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vehicle
Description: Topical eyedrop
Study NCT05237622 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: High Flow
Description: Standard HighFlow therapy after weaning from continuous positive airway pressure therapy will be applied on different flow levels. Starting with a flow level of 8l/min, the flow-rates will be changed every 30 minutes subsequently from 8-6-4-2-4-6-8 l/min. Meanwhile, data on lung volume changes will be measured using electrical impedance tomography.
Study NCT06030726 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Economic Principles
Description: The control arm will receive no letter to reflect the background vaccination uptake. Intervention arms will test the effects of different letters developed using behavioral economic principles.
Study NCT05755594 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Robot-assisted Pancreaticoduodenectomy
Description: By performing pancreaticoduodenectomy on the subject using the latest generation Da Vinci robotic surgical system and assisted by another surgeon for the entire procedure
Study NCT05616611 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: High-Intensity laser
Description: intervention that lasted 3 sessions/week for 12 weeks).
Study NCT05616611 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physiotherapy exercises
Description: intervention that lasted 3 sessions/week for 12 weeks).
Study NCT05616611 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Shock Wave therapy
Description: intervention that lasted 3 sessions/week for 12 weeks).
Study NCT05183100 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tibial Nerve Neurodynamics
Description: The patient will lie supine with the trunk and neck in neutral position. During the first stage, participants will receive passive straight leg raise of the affected side held for 20 seconds for 3 repetitions. In the second stage, hip adduction and internal rotation, ankle dorsiflexion, and ankle eversion are added in the straight leg raise position. Slow oscillations of the ankle movement for 1 minute will be applied, followed by holding the position for 20 seconds, for 3 repetitions. In the third stage, the head of the patient will be held in flexion with pillows while the same oscillation procedure as the second stage is performed. There will be a 2-minute rest between the stages.
Study NCT05183100 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Lying in supine
Description: Lying in supine position for about 13 minutes.
Study NCT06455189 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control Group - Standard of care neurosurgical resection
Description: The control group will include only standard of care tools. - Standard of care neurosurgical resection will include the use of all standard neurosurgical instruments and techniques (eg, microscope, intraoperative ultrasound, 5-ALA fluorescence guided surgery and neuronavigation system).
Study NCT06455189 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MRF/MRI infiltration guidance for extended resection
Description: Magnetic resonance imaging, MRI, is a procedure that uses radio waves, a powerful magnet, and a computer to make a series of detailed pictures of areas inside the body
Study NCT05919459 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5-week online synchronous ACT intervention
Description: Parents will meet a trained ACT counsellor to undergo five weekly sessions of ACT group training via Zoom. Specifically, each 120-minute synchronous videoconferencing session will involve the ACT counsellor and 6-8 parents.
Study NCT05919459 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asynchronous online AIS education
Description: A healthcare educator with a background in nursing, physiotherapy, or occupational therapy will meet with parents in five weekly 120-minute interactive AIS-related education videoconferencing via Zoom. Specifically, each 120-minute synchronous videoconferencing session will involve the ACT counsellor and 6-8 parents.
Study NCT05919459 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: asynchronous online AIS education
Description: A healthcare educator with a background in nursing, physiotherapy, or occupational therapy will meet with parents in five weekly 120-minute interactive AIS-related education videoconferencing via Zoom. Specifically, each 120-minute synchronous videoconferencing session will involve the ACT counsellor and 6-8 parents.
Study NCT06338683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olanzapine 2.5 MG
Description: Oral olanzapine 2.5 mg once daily at bedtime until disease progression
Study NCT06338683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard anti-tumor treatment
Description: Clinicians choose the appropriate standard antitumor drug therapy based on the patient's specific situation
Study NCT06338683 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard anti-tumor treatment
Description: Clinicians choose the appropriate standard antitumor drug therapy based on the patient's specific situation
Study NCT06338683 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutritional advice
Description: All patients enrolled in the study were required to undergo a nutritional assessment and were provided with nutritional advice based on their condition
Study NCT06338683 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Nutritional advice
Description: All patients enrolled in the study were required to undergo a nutritional assessment and were provided with nutritional advice based on their condition
Study NCT06173895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3454738
Description: Administered subcutaneously (SC)
Study NCT03843437 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tencel Therapeutic Garments
Description: Children age 6 months to 3 years will wear a Tencel full body suit with feet and mittens, while children age 3-6 years will wear Tencel long-sleeve shirts and pants that do not cover the hands and feet. Children will wear the study garments at night but may also wear garments during the day if desired.
Study NCT03843437 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Cotton Therapeutic Garments
Description: Children age 6 months to 3 years will wear a cotton full body suit with feet and mittens, while children age 3-6 years will wear cotton long-sleeve shirts and pants that do not cover the hands and feet. Children will wear the study garments at night but may also wear garments during the day if desired.
Study NCT06114823 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: carpal tunnel release mini-incision
Description: Patients were subjected to a longitudinal mini-incision started just above the proximal flexor wrist crease and then extended for 1.5 - 2 cm in a proximal direction
Study NCT06114823 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: carpal tunnel release conventional incision
Description: Patients were subjected a longitudinal incision which was created between the thenar and hypothenar eminences along the longitudinal axis of the ring finger. Then, it was extended to the proximal flexor wrist crease.
Study NCT06325982 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triethanolamine cream
Description: Triethanolamine cream retention enema was given once every night before going to bed during radiotherapy until the end of radiotherapy. Triethanolamine cream retention enema was given once before going to bed the day after radiotherapy for 3 months.~Preparation method: Pull out the syringe piston, add 15ml triethanolamine cream, add 30ml normal saline, gently pat, shake well.~Specific methods of retention enema: at night before going to bed, empty urine and feces, prepare enema liquid into the syringe, connect the special catheter, and insert the other end of the special catheter into the anus (the special catheter can be applied with lubricant such as tea oil before insertion). The patient remained prone and semi-seated. Use a special catheter, insert a special catheter about 15cm from the anus, and inject enteral liquid while withdrawing, so that the liquid is retained in the rectum; The above treatment was performed before bed and retained overnight.
Study NCT06547203 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Cetuximab: 500 mg/m², intravenous infusion, once every 2 weeks
Study NCT06547203 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab: 3 mg/kg, intravenous infusion, once every 2 weeks.
Study NCT06547203 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan: 150 mg/m², intravenous infusion, once every 2 weeks.
Study NCT05463458 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: nutrition
Description: Standard of nutrition Care plus adjusted and calculated dose of omega-3 polyunsaturated fatty acids (PUFA) anti-oxidants.
Study NCT05463458 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: nutrition
Description: Standard of nutrition Care plus adjusted and calculated dose of omega-3 polyunsaturated fatty acids (PUFA) anti-oxidants.