AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06221189 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACT-CSP
Description: The ACT treatment will consist of three 45 to 60-min weekly sessions to be delivered to the caregiver in an individual format via online videoconferencing application e.g. ZOOM or WhatsApp within 3 weeks. The ACT-CSP can be delivered via face-to-face on request. Each session has a specific content with pre-planned materials and mindfulness exercises and metaphors. Psychological-based homework will be assigned at the end of each session. The components of ACT process will be emphasized in the intervention programme, which include perspective taking, self-as-context and defusion (i.e. recognizing worry thoughts as thoughts only), identifying values and acceptance of present-moment experience with respect to the values, and committed action.
Study NCT04927754 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was assessed the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's pain during dental care.
Study NCT04998617 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Toothpaste without curcumin
Description: Subjects will be given toothpaste to be used during this study without curcumin
Study NCT06397365 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: medical hypnosis
Description: The first hypnosis session (V2) consists of a safe place suggestion. Through this type of suggestions, patients will safely experience the dissociative state, and will be given tools (recordings of sessions) to perform self-hypnosis at home between the visits. The suggestions will help the patient to visualize an imaginary place where they feel well and safe, a protective place to rest. In this first session, CPAP treatment will be introduced during hypnosis, with specific suggestions relating to the use of this treatment.~The second session (V3) The second session will also use the safe place. We will adapt the suggestions according to the experience reported by the patient on the day of the visit. During this session, we'll focus on changes in the patient's perception of the CPAP machine.~Patients will also be given the recording of each session to perform self-hypnosis at home between the visits.
Study NCT04927754 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dental anxiety assessment
Description: Conventional behavior guidance technique was used in one of the different treatment sessions with intervals of two weeks for both groups, and the cartoon-assisted distraction technique was used in the other. It was evaluated the effect of the cartoon-assisted audio/visual distraction technique usage on paediatric patient's dental anxiety during treatment sessions.
Study NCT05861609 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care with respect to Spinal Cord Stimulation implantation
Study NCT05861609 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standardized pain medication tapering
Description: A standardized pain medication tapering program before Spinal Cord Stimulator implantation.
Study NCT05861609 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Personalized pain medication tapering
Description: A personalized pain medication tapering program before Spinal Cord Stimulator implantation.
Study NCT05276830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BXCL501
Description: Sublingual film containing 40 Micrograms BXCL501
Study NCT05276830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BXCL501
Description: Sublingual film containing 60 Micrograms BXCL501
Study NCT05276830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo film
Description: Matching Sublingual Placebo film
Study NCT06448351 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and urine sample collection
Study NCT05353556 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle Training (IMT)
Description: The IMT protocol will consist of home-based high-intensity daily training - two cycles of 30 breaths with a 1-min rest between sets, twice a day for 8 weeks using an IMT Threshold device (Threshold IMT Philips® Respironics, Inc). The intensity of the training will be set to 50% of each patient's maximal inspiratory pressure measured every week and was adjusted weekly based on the modified Borg scale from 4 to 6 regarding respiratory effort performed during the session.
Study NCT05353556 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham IMT
Description: The IMT protocol will consist of home-based daily training - two cycles of 30 breaths with a 1-min rest between sets, twice a day for 8 weeks using an IMT Threshold device (Threshold IMT Philips® Respironics, Inc). The intensity of the training will be set to the lowest intensity of the IMT Threshold device.
Study NCT06318650 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Demineralized Dentin Matrix
Description: preparation of Allogenic Demineralized Dentin Matrix: Extracted teeth will be collected from the Departments of oral maxillofacial surgery and periodontics, Cairo university. Cleaning the teeth from any caries, Filings, cement, tartar, soft tissue debris and prosthetic components will be performed using a diamond bur under abundant irrigation with physiological water. Then it will be proceeded to the following steps~1. (Washing with Distilled water ) 2. (Quick Freezing with liquid nitrogen, then Grinding to particle size of 300- 800 μm). 3.(Ultrasonic Cleaning cycles, 1st with Distilled water , 2nd with 5-7% Hydrogen Perioxide then 3rd with Distilled water for at 60-80 o) 4. (Defatting with Chloroform Methanol Solution1:0.5. 5. (Demineralization with0.5N HCL) 6. (Dehydration with Neutral Ethyl Alcohol then Defatting with Chloroform Methanol Solution 1:0.5 for ) 7. (Washing with Normal Saline \& Freeze Drying then Sterilization using Ethylene oxide gas).
Study NCT06318650 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Demineralized freeze-dried bone allograft (DFDBA)
Description: combination allograft, is a particulate bone graft combining 70% mineralized ground cortical with 30% demineralized ground cortical Particle sizing: 250 - 1000um.
Study NCT06449079 — intervention group
Intervention type: OTHER
Intervention: Machine learning
Description: Analysis of data with machine learning methods
Study NCT06448351 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Carbon Monoxide Measurement
Description: Undergo CO test
Study NCT05634187 — intervention group
Intervention type: DEVICE
Intervention: Functional endoscopy
Description: Transnasal endoscopy by an ultrathin video endoscope
Study NCT05050617 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Point-of-care echocardiography
Description: Subjects will undergo point-of-care echocardiography at the time of presentation/enrollment to assess for evidence of right sided heart dilation/strain.
Study NCT05113225 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Micro-swim up technique
Description: processing and selection of the sperm for ICSI in the same dish
Study NCT05113225 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Micro-swim up technique
Description: processing and selection of the sperm for ICSI in the same dish
Study NCT05740670 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dr. Kellyann's Bone Broth
Description: Participants will have two bone broth phases, each three weeks in length. Bone broth phases will be separated by a one-week maintenance phase. A one-week maintenance phase will also occur after the second bone broth phase. Each week of a broth phase will consist of five feeding days and five fasting days. On feeding days, participants will consume one packet of bone broth, twice each day, as snacks between meals. On fasting days, participants will consume one packet of bone broth every two hours for a total of seven packets each day.
Study NCT06448351 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vaping session
Description: Sample study e-liquids in vaping sessions at research lab with e-cig study device
Study NCT05494814 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Child Care Centers Served Meals Prepared by Central Kitchen
Description: The child care centers who are served by the central kitchen will receive meals that include locally sourced fresh fruits and vegetables to serve their staff and children.
Study NCT05854056 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conservative rehabilitation protocol
Description: See Arms section
Study NCT05378906 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV/COBI FDC
Description: Participants will receive a single oral dose of DRV/COBI FDC tablet dispersed in water as per assigned treatment sequence.
Study NCT05378906 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: COBI
Description: Participants will receive a single oral dose of COBI tablet as per assigned treatment sequence.
Study NCT05378906 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DRV
Description: Participants will receive single oral dose of DRV suspension as per the assigned treatment sequence.
Study NCT06448351 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT06550986 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: False Lumen Embolization System, IMPEDE-FX RapidFill
Description: Embolization of the false lumen of an aortic dissection
Study NCT06370026 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: KSD-101
Description: Patients will receive approximately 5x10\^6 DC vaccine via subcutaneous injections bi-weekly,total 3-5 times.
Study NCT04766762 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture combined with placebo
Description: This group will include 48 patients. Patients in this group will receive acupuncture combined with placebo. Participants are in the supine position. The bilateral Tianrong (SI 17) acupoints are needled for 1-1.5 inch with the direction tilted back 45±5 degrees. The bilateral Fengchi (GB 20) acupoints are needled for 0.5-1 inch with the direction tilted to nose. The bilateral Neiguan (PC 6) acupoints are also needled for 0.5-1 inch with the straight direction. In addition, 4-6 additional acupoints can be identified according to different syndrome types of patients. The needles are kept for 30 min, the treatment frequency is 3 times per week, and the treatment duration lasts 8 weeks. Meanwhile, the dosage of placebo is 1 capsule twice a day and the treatment duration also lasts 8 weeks.
Study NCT04766762 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Sham acupuncture combined with flunarizine hydrochloride
Description: This group will include 48 patients. Participants in this group will receive sham acupuncture plus flunarizine hydrochloride. Participants are in the supine position and sham acupuncture is conducted. The bilateral Tianrong (SI 17) acupoints, Fengchi (GB 20) acupoints and Neiguan (PC 6) acupoints are selected, and 4-6 additional acupoints can be identified according to the syndrome type of the participants. The needles are kept for 30 min, the treatment frequency is 3 times per week, and the treatment duration lasts 8 weeks. Moreover, the dosage of flunarizine hydrochloride is 5mg twice a day and the treatment duration also lasts 8 weeks.
Study NCT05327387 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: model-based electrical brain stimulation
Description: Electrical pulse train stimulation delivered to medication refractory epilepsy patients with electrodes already implanted based on clinical criteria for standard monitoring unrelated to this study. The delivery of the electrical brain stimulation can be guided by neural biomarkers of symptom levels computed from ongoing neural activity and by input-output models of neural response to stimulation therapy. The parameters of electrical stimulation will be constrained to be within clinically safe ranges.
Study NCT05402657 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy
Description: UBRUL-FP involves ultrabrief right unilateral ECT delivered using a novel frontoparietal montage, where the anterior electrode is shifted frontally to a position above the midpoint of the right eye to avoid temporal lobe stimulation (and reduce memory side effects). UBRUL-FP will be delivered using standard ECT devices.
Study NCT05402657 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy
Description: UBRUL-TP is the standard form of ultrabrief right unilateral ECT, using the conventional temporoparietal (d'Elia) electrode placement, where the anterior electrode is placed over the right temporal lobe. UBRUL-TP will be delivered using standard ECT devices.
Study NCT06570941 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chylobinoid Topical Cream
Description: The topical cream is applied to the effected area to reduce or eliminate the symptoms of restless leg syndrome
Study NCT04056533 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CMV CTLs
Description: The donor derived cytomegalovirus specific T lymphocytes (CMV-CTL) will be transfused to the patients. The patients will receive CMV-CTL cells when their donors are sero-positive for CMV-DNA 21 days after transplant. The CMV-DNA levels will be monitored weekly for at least 100 days after the HAPLO. If after the initial dose of CMV-CTL cells the patient develops a viral infection, then they may be eligible to receive a CMV specific antiviral drug.
Study NCT05967299 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZMA001 (BC-NKA-20008)
Description: ZMA001 is a fully human, monoclonal antibody (IgG1) that inhibits migration of activated monocytes and macrophages and reduces pulmonary vascular remodeling and pulmonary artery pressure in pre-clinical rodent models of pulmonary arterial hypertension (PAH).
Study NCT05967299 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 30mg/ml Sucrose
Study NCT06208202 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral Intervention
Description: Receive and use flavored e-cigarettes (EC) as directed
Study NCT06208202 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo biosample sample collection
Study NCT06208202 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Survey Administration
Description: Complete surveys
Study NCT05840211 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan-hziy
Description: Administered intravenously
Study NCT05840211 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Administered intravenously
Study NCT05840211 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nab-paclitaxel
Description: Administered intravenously
Study NCT05840211 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: Administered orally
Study NCT05209464 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tele-Tai Chi
Description: Study participants will follow a 12-week simplified Tele-Tai-Chi (TC) program delivered via an application installed on a tablet. The intervention emphasizes essential TC movements that are easily comprehensible and can be performed repetitively in a flowing manner. The protocol includes up to six core TC movements based on the traditional Cheng Man-Ch'ing's Yang-style short form. Additionally, a set of traditional TC warm-up exercises that focus on loosening the physical body, incorporating mindfulness and imagery into movement, promoting overall relaxation, and coordinating breathing awareness are included. Chairs are used in the protocol for a subset of seated warm-up exercises, as well as for stability and rest as needed. Participants will be asked to practice the protocol (45-60 min) at home for at least 3 days a week for 12 weeks. The TC program will also include 2 or more live instructional sessions via Zoom with a TC instructor.
Study NCT06533956 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 10-week gait training program combined with simultaneous blood flow restriction (BFR).
Description: The children will receive a 10-week intervention (1 week of habituation without BFR + 9 weeks with BFR) comprising 3 30-minute treadmill sessions per week. At each session, the first 5 minutes will enable a gradual increase in speed, and then the maximum tolerated walking speed will be sought. Maximum speed corresponds to the walking speed maintained by the child for an effort of between 5 and 7 on Borg's 10-point VAS. The rehabilitator will encourage the child to maintain this speed and provide feedback on performance. The BFR setting will maintain an occlusion, at the root level of both lower limbs, of 60% of the total occlusal pressure.
Study NCT05342623 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Difelikefalin 1 mg Oral Tablet
Description: Difelikefalin 1 mg medication taken orally 1 time/day
Study NCT05342623 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Placebo tablet taken orally 1 time/day
Study NCT04793490 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sphenopalatine ganglion block
Description: Patients will receive the SPGB via the transnasal approache by a cotton tipped applicator soaked in lignocaine 2% with 4 mg dexamethasone
Study NCT04793490 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: paracetamol
Description: patients will receive paracetamol 1 g thrice daily intravenously
Study NCT05582408 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Measures of Standard Noise Reduction NR1
Description: Each participant will be fitted with the Standard Noise Reduction (NR1)
Study NCT05582408 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Measures of Noise Reduction Principle NR2
Description: Each participant will be fitted with the novel Noise Reduction principle NR2 on the same hearing aid
Study NCT05582408 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Measure of Noise Reduction Principle NR3
Description: Each participant will be fitted with the novel Noise Reduction principle NR3 on the same hearing aid
Study NCT04957537 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: semantic therapy and semantic re-education
Description: Patients will be followed over two periods Phase A (randomized, 6 to 8 weeks) - Phase B (5 weeks).~Phase A : Baseline Phase A, which constitutes the control period of semantic therapy, will be composed of lexico-phonological training exercises (Piroux-Davous, 2018). This phase will last 6 to 8 weeks (i.e. 18 to 24 sessions) depending on the randomisation, at the rate of 3 speech therapy sessions of 45 minutes per week.~Phase B : Semantic re-education The sessions will consist of training based on the analysis of semantic traits (Coustaut, 2019). This phase will last 5 weeks (i.e. 15 sessions), at the rate of 3 speech therapy sessions of 45 minutes per week.~In accordance with the application of the SCED methodology, repeated measurements will be carried out every second session during phases A and B. They will consist of proposing the oral naming task (lasting 10 minutes).
Study NCT06513351 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Novel PPH Risk Prediction Model - Comparator Arm B
Description: Patients in this group will receive the standard care risk assessment with the addition of a recently developed, novel PPH risk prediction model, which will automatically calculate a patient's numerical risk of hemorrhage based on 21 risk factors. Elevated risk of hemorrhage (>=3% predicted risk), as predicted by the model, will be linked to clinical decision support, including a best practice advisory with recommendations presented to providers for consideration when they access the patient's electronic health record.
Study NCT04987879 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Aerobic exercise can be completed by walking, jogging or running or by using cardio equipment (e.g., recumbent bike). Each session will begin with a warm-up with walking (30-40% target HR for 5-min) and dynamic exercises (knee-to-chest, 10-yd lateral shuffle, bent over twist, calf sweeps, leg swings). A 5-min walking cool down will end the session (30-40% target HR).
Study NCT05597254 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic with niacin and berry extract
Description: 1 capsule daily of probiotic with niacin supplementation for 8 weeks
Study NCT05597254 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic without niacin and berry extract
Description: 1 capsule daily of probiotic without niacin supplementation for 8 weeks
Study NCT05597254 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 capsule daily of placebo supplementation for 8 weeks
Study NCT04665635 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rectosigmoid resection
Description: Most of the colorectal involvements are observed in the seromuscular layer. In seromuscular infiltration, resection of the rectosigmoid colon or shaving of tumoral implants without resection can be performed.
Study NCT05066230 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KSI-301
Description: Intravitreal injection
Study NCT05384626 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVL-655
Description: Oral Tablet of NVL-655