AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04702672 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 100% regular barley
Description: Intake of 250 ml of tap water and 100 g of bread baked with 100% regular barley flour and 25% wheat flour. Consumed over maximum 10 minutes at time 0 min after overnight fasting. At one of four visits.~HIAMBA® are naturally bred in corporation with PlantCarb ApS and researchers at Aarhus and Copenhagen Universities. The wheat flour is standard commercial available flour.
Study NCT05290818 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MAKO™ Partial Knee Arthroplasty
Description: The robotic-arm will be used to position a partial knee arthroplasty.
Study NCT05290818 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Triathlon (Stryker) Total Knee Arthroplasty
Description: Triathlon (Stryker) TKA with a cruciate retaining polyethylene insert.
Study NCT04650841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Cream with Naloxone
Description: Participants will be informed that the spray is an effective pain and negative emotion reducing agent.
Study NCT04650841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Control Cream with Naloxone
Description: Participants will be informed that the spray is saline.
Study NCT04650841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Cream with Saline
Description: Participants will be informed that the spray is an effective pain and negative emotion reducing agent.
Study NCT04650841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Control Cream with Saline
Description: Participants will be informed that the spray is saline.
Study NCT04900935 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: POISE
Description: POISE (Patient-centered, Optimal Integration of Survivorship and palliative carE) is a brief, population-specific intervention that consists of four sessions with palliative care specialists who have been additionally trained to evaluate and address the specific psychosocial issues and health-promoting behaviors of patients with long, uncertain cancer trajectories.
Study NCT06246721 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-management of vaginal pessary
Description: Self-management of vaginal pessary
Study NCT06246721 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Self-management of vaginal pessary
Description: Self-management of vaginal pessary
Study NCT06009978 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neuromuscular electrical stimulation (NMES)
Description: Neuromuscular electrical stimulation (NMES) 2 times a day á 15 minutes from the third to the eight week after injury. The additional treatment will be perform in the patients home by themselves
Study NCT05035927 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TRYP-0082
Description: A single (1) 25 mg oral dose of TRP 8802 will be administered in a carefully monitored setting following 6 to 8 hours of preparatory psychotherapy. Subjects will be in the study for 12 weeks following the dose of TRP 8802 (until Week 14), approximately 5 months from initiation of screening through the last follow-up.
Study NCT05035927 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: A single (1) 25 mg oral dose of TRP 8802 will be administered in a carefully monitored setting following 6 to 8 hours of preparatory psychotherapy. Subjects will be in the study for 12 weeks following the dose of TRP 8802 (until Week 14), approximately 5 months from initiation of screening through the last follow-up.
Study NCT06359561 — intervention group
Intervention type: DEVICE
Intervention: cervical lead placement
Description: implant of cervical lead neurostimulation, using saluda medical devices
Study NCT05257018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: R-CDOP+intrathecal MTX
Description: R-CDOP+intrathecal MTX：~* Rituximab 375 mg / m\^2，D1~* Cyclophosphamide 750 mg / m\^2，D2~* Doxorubicin Hydrochloride Liposome Injection 35mg / m\^2，D2~* Vincristine 1.4mg/m\^2 (dose capped at 2 mg)，D2~* Prednisone 50 mg， bid D2-6~* Cycle1-5：Intrathecal MTX 12 mg + DXM 5 mg after chemotherapy （PK patients will be given 24 h after chemotherapy）
Study NCT06070480 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Anesthesia Group
Description: Effect of spinal anesthesia on intraocular pressure
Study NCT06070480 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Desflurane Group
Description: Effect of general anesthesia with desflurane on intraocular pressure
Study NCT06070480 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Propofol Group
Description: Effect of general anesthesia with propofol on intraocular pressure
Study NCT06405854 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Children in the coordinative exercise intervention group will be encouraged to participate in sessions twice a week, each lasting 20 minutes. The foundational movement patterns tailored to the specific purpose were organized in a game format suitable for preschool-aged children. These foundational movement patterns comprise open-ended tasks progressing from simple to complex, with motor planning as a prerequisite. As the exercise intervention was game-based, the sessions were maintained as a fun, active, and social learning environment for the children. Duration of the intervention is eight weeks,
Study NCT05191862 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Cilostazol 100 mg
Description: One Cilostazol 100 mg at 08:00 and another at 20:00, two oral doses (total daily dose of 200 mg)
Study NCT05191862 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: PMR 135 mg
Description: Two PMR 135 mg at 08:00, single oral dose (total daily dose of 270 mg)
Study NCT04848571 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Fetal Protection Pill
Description: A Chinese medicine used in pregnant women for fetal protection, including mainly Rehmannia glutinosa.
Study NCT04848571 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Fetal Protection Pill
Description: A Chinese medicine used in pregnant women for fetal protection, including mainly Rehmannia glutinosa.
Study NCT05556967 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immulina
Description: Immulina is a highly standardized extract derived from various preparations of Spirulina, a cyanobacterium, marketed as a dietary supplement and has been utilized in several clinical studies describing its immunopotentiating properties.
Study NCT06481969 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Conventional IVF
Description: Conventional In Vitro Fertilization (IVF) procedure and standard assisted reproductive treatments.
Study NCT06481969 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lower abdominal liposuction and preparation of SVF
Description: After lower abdominal liposuction (the liposuction volume is about 100 ml), the preparation and quality inspection of SVF will be completed by a laboratory with good manufacturing practice-approved facilities immediately. The adipose tissue will be cut into pieces of about 1mm3, and the equal volume of 0.1% collagenase I will be added to digest the adipose tissue. The digestion will be terminated after 40 minutes, followed by isolation, filtration, centrifugation, resuspension and dilution to obtain the SVF suspension. The test items, including bacteria, fungi, viruses and endotoxin, will be tested, and the expression of SVF surface markers, including CD45, CD34, CD31, CD11b, CD44, CD73, CD105 and CD90, will be detected by flow cytometry to ensure the quality of the SVF suspension. After about 4 hours of quality control and detection, the SVF suspension will be transported to the operating room on ice in a sealed incubator.
Study NCT06481969 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ovarian injection
Description: Under ultrasound guidance, the SVF suspension will be injected into patients' bilateral ovaries. SVF with a total amount of (1\~2)×107 cells from autologous fat tissue will be transplanted into each side of ovary. There are 3 injection points on each side of ovary, and 330±10μl SVF suspension will be administered at each point. The administration volume of each ovary will be 1ml in total. After injection, the patients will be required to lie flat for 2 hours to observe whether there would be adverse events.
Study NCT05528666 — intervention group
Intervention type: OTHER
Intervention: High Efficacy Therapy (HET)
Description: HET include alemtuzumab, ofatumumab, ocrelizumab, natalizumab, cladribine, fingolimod and ozanimod.
Study NCT05528666 — intervention group
Intervention type: OTHER
Intervention: Non High Efficacy Therapy (Non-HET)
Description: Non-HETs include molecules classified as with moderate or modest efficacy such as: interferons, glatiramer acetate, dimethyl fumarate and teriflunomide.
Study NCT04651374 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: geko T3
Description: The device stimulates the peroneal nerve.It will be applied for the entire duration of ICU stay and replaced once every 24 hours.
Study NCT05358782 — intervention group
Intervention type: DEVICE
Intervention: Dental implant positioning
Description: observational study of the effect of implant malposition
Study NCT06478940 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3 mixtatin pulpotomy
Description: pulp treatment with applying 3mixture of antibiotic (Metronidazole, cefixime, and Ciprofloxacin) along with simvastatin
Study NCT06478940 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MTA pulpotomy
Description: pulp treatment with applying MTA
Study NCT05754112 — intervention group
Intervention type: OTHER
Intervention: B lymphocyte profiling
Description: All individuals will undergo peripheral venous blood sampling and ultrasound-guided synovial tissue biopsy following a standardized procedure. B-lymphocytes will be sorted from PBMCs isolated by Ficoll gradient method using magnetic CD19-microbeads whereas tissue B-lymphocytes will be isolated from synovial tissue biopsies digested with Liberase. CD19 positive cells from PBMC will be incubated with pro-inflammatory molecules in presence or absence of Ubadacitinib. After stimulation, CD19 positive cells will be collected and processed for single cell RNA sequencing. Moreover, the impact of JAK-1 selective inhibition on B-lymphocyte cultures stimulation will be tested using ELISA method for the assessment of cytokines/chemokines production. Synovial tissue and synovial tissue B-lymphocyte subpopulations will be assessed through FACS analysis using IgD/CD27 classification. Finally, we will compare the transcriptomic profile of synovial tissue B lymphocytes from 5 subject groups.
Study NCT06427174 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fascia iliaca block
Description: For the group who will receive the fascia iliaca block .... After induction of the general anesthesia and before skin incision, fascia iliaca block will be performed in the patient while he is in the supine position
Study NCT06427174 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Caudal block
Description: second group will receive the caudal block, we use bupivacaine 0.5 mg / kg.
Study NCT06468410 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: long duration Hatha Yoga
Description: 60 min of Hatha yoga for 4 weeks. Week One:Participants begin with foundational breathing and yoga practicesOn the second day, Square Breathwork is introduced to foster calm and concentration. After a warm-up, the yoga flow focuses on heart openers to increase chest and shoulder flexibility, ending with a soothing cool-down. Week Two:Advanced breathing techniques and targeted yoga flows are introduced. The second session includes Nadi Shodhana to balance the nervous system. Week Three:The focus remains on heart openers with varied breathing exercises. The second day revisits Full Yogic Breath, followed by a warm-up and another heart opener sequence, concluding with a cool-down. Week Four:The final week integrates additional breathing techniques. The last session features Kapalabhati and Suddhi Pranayama to purify and energize the body. After a warm-up, participants engage in a well-rounded yoga flow combining various poses to enhance overall fitness, concluding with a final cool-down.
Study NCT06468410 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: short duration Hatha Yoga
Description: 30 min of Hatha yoga for 4 weeks .
Study NCT06468410 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: participants will receive information about physical activity guidelines but will not engage in any structured yoga exercise during the study period.
Study NCT05149209 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cervical restoration
Description: A class v cavity will be prepared after local anesthesia has been given as required. Rubber dam isolation will be done. Selective enamel etching and a universal adhesive agent (Beautibond, Shofu, Japan) will be applied over all the cavity surfaces. Followed by, placement of restorative material according to the randomization sequence. Finally, restoration finishing and polishing will be done.
Study NCT05149209 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cervical restoration
Description: A class v cavity will be prepared after local anesthesia has been given as required. Rubber dam isolation will be done. Selective enamel etching and a universal adhesive agent (Beautibond, Shofu, Japan) will be applied over all the cavity surfaces. Followed by, placement of restorative material according to the randomization sequence. Finally, restoration finishing and polishing will be done.
Study NCT05603351 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: magnetic resonance
Description: biparametric MRI with protocol including anatomical T2 sequence and diffusion-weighted images (DWI), according to the standards
Study NCT05603351 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: serum PSA examination
Description: testing of prostate-specific antigen (PSA) in serum
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: Trastuzumab (6mg/Kg, iv.drip, d1, q3w)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pertuzumab
Description: Patuzumab (420mg iv.drip, d1,q3w)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: nab-paclitaxel (200mg iv.drip, d1,d8, q3w)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib
Description: Pyroltinib (400mg po qd)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine (1250mg/m2, po, bid, d1-d14, q3w).
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: T-DM1
Description: T-DM1(3.6mg/Kg, iv.drip, d1, q3w)
Study NCT05045963 — intervention group
Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical record reviewed
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: Everolimus (4mg, po, qd)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CDK4/6 inhibitor
Description: Palbociclib (125mg, po, qd)
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AI
Description: Letrozole (2.5mg, qd).
Study NCT05429684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 monoclonal antibody
Description: Cindilimab (200mg, iv.drip, d1, q3w)
Study NCT05587543 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PK Blood Collection
Description: All subjects were subjected to PK blood sampling as prescribed by the protocol.
Study NCT05587543 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAR
Description: Target A positive subjects will receive CAR-T cell therapy.
Study NCT05587543 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCR
Description: Target A negative, Target B positive and Target C positive subjects will receive TCR-T cell therapy.
Study NCT05596240 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling
Description: A sterile, disposable, solid filament needle (Seirin Corp., Shizuoka, Japan) will be inserted manually into the MTrP of the infraspinatus muscles. Once the needle has been inserted, the technique described by Hong (1994) will be used. The needle will be pistoned in an up and down motion within the infraspinatus muscle at approximately 1Hz for 10 seconds with the aim of eliciting local twitch responses.
Study NCT05596240 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham Dry Needling
Description: Streitberger Placebo-needles (Asia-med, Las Vegas, NV) will be used to perform the intervention for participants in the sham DN group. These needles have been reported to be indistinguishable from real needles. The device consists of a plastic tube with a blunted tip needle that allows for the sensation of a prick without penetrating the skin. The sham needle produces a sensation, which causes the participant to feel as if the needle enters the skin, while maintaining similar patient-therapist contact time and total intervention time.
Study NCT05725525 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Remote PCIT augmented with wearable devices
Description: Participants will be enrolled in remote PCIT and be asked to wear a Garmin watch throughout the course of the study in order to measure biometric fluctuations
Study NCT05264675 — intervention group
Intervention type: PROCEDURE
Intervention: primary suture
Description: Primary suture of the EPL-tendon
Study NCT05264675 — intervention group
Intervention type: PROCEDURE
Intervention: EIP-transfer
Description: transfer of the EIP-tendon to the EPL-tendon
Study NCT04785807 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post traumatic, Anxiety and depression evaluation
Description: Family member of person or trust of patient who had a limitation or discontinuation of treatments will be identified and asked to fulfilled a hospitalized anxiety and depression scale and the revised Impact Event scale 7 and 30 days after the limitation or discontinuation of treatments announcement
Study NCT06041828 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lumoral Treatment
Description: Photodynamic antibacterial dual-light device with a marker substance
Study NCT06041828 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard oral hygiene
Description: Standard oral hygiene instructions
Study NCT06041828 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard oral hygiene
Description: Standard oral hygiene instructions
Study NCT04367935 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pentoxifylline
Description: Pentoxifylline tablets 400mg three times daily for 2 months
Study NCT05303974 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound guided joint injection
Description: The participants will perform two ultrasound guided joint injections on a mannequin. The performance of both procedures are videorecorded. All videos will be rated by two blinded raters using the modified IUSE assessment tool.
Study NCT05431751 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Whole Algae
Description: Whole Euglena gracilis algae, produced by proprietary fermentation.
Study NCT04875273 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Tape® aplicación
Description: Magnetic tape® is applied without creating any tension on the paravertebral skin of the lumbar spine
Study NCT04875273 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Kinesiology Tape application
Description: Kinesiology tape is applied without creating any tension on the paravertebral skin of the lumbar spine
Study NCT05497505 — intervention group
Intervention type: DEVICE
Intervention: Pacmed Critical
Description: For patients in the On-period, Pacmed Critical will be available as decision support after initial eligibility screening for ICU discharge by treatment team
Study NCT05068596 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: expermintal
Description: progressive resistive functional strength training in the plantigrade foot position plus designed physical therapy program
Study NCT05068596 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: CONTROL
Description: Designed physical therapy program
Study NCT05777811 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vertically coronally advanced flap combined with connective tissue graft.
Description: The exposed root surfaces are planed with Gracey 1-2 curettes. An intrasulcular incision is made with a blade on the buccal aspects of the involved teeth. The incision is extended horizontally to the adjacent papilla. Then, slightly divergent vertical releasing incisions are carried 2 mm beyond the mucogingival junction. A full-thickness flap is raised with a periosteal elevator towards the mucogingival junction. After that, a partial-thickness dissection is carried out in the apical direction to release muscle tension and provide coronal advancement of the flap. The adjacent papillae are de-epithelialized. The connective tissue graft (CTG) is harvested from the lateral palate using the de-epithelialized gingival graft technique. After harvesting, the connective tissue graft is sutured to the recipient bed. Finally, the flap is positioned 2 mm over the cementoenamel junction and sutured with 6-0 polypropylene sutures. No periodontal dressing is applied.