AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05560932 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IMB-motivational interviewing (MI) techniques (IMB-MI)
Description: The clinical pharmacist will employ MI in informational, participant-centered discussions in which the clinical pharmacist and participant collaboratively discuss the harms of drinking and polypharmacy (specifically alcohol interactive medications), symptoms associated with alcohol and specific medications, and how to mitigate these harms. Motivational elements include messages highlighting the participant's personal risk of bothersome symptoms from their use of alcohol and level of polypharmacy, attitude change elements to improve attitudes toward the intended behavior change, social normative support for the intended behavior change including identification of people who can support the participant in this process, and a menu of options for referrals for skill building (e.g. Social Work, meeting with the clinical pharmacist at their clinic, follow-up with the HIV clinician, alcohol-reduction programs, based on what is locally available as part of VA-based care).
Study NCT05334446 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Effect of the Mobile Application
Description: This study was planned to determine the Effect of Mobile Application Use on Treatment Adherence and Self-Care Management in Patients with Hypertension. The study was designed to improve individuals' knowledge about the disease, regular drug use, diet compliance, physical activity level, quitting smoking and alcohol if using, and weight control.
Study NCT06770634 — intervention group
Intervention type: OTHER
Intervention: Bioelectrical Impedance Analysis
Description: With Bioelectrical Impedance Analysis, fat, muscle and water ratio and lean mass are calculated in addition to the patient's body weight.
Study NCT06770634 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: Measurement of subcutaneous fat tissue thickness from mid-thigh, pretibial, lateral leg and supramalleolar regions with ultrasound.The average of two measurements taken from the same area will be recorded.According to these measurements; 12-15 mm = mild lipedema or lipohyperplasia, 15-20 mm = moderate lipedema, >20 mm = significant lipedema, >30 mm = severe lipedema.
Study NCT06771141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Video Session
Description: This intervention involves a 10-minute virtual reality (VR) video session designed to reduce pre-procedural anxiety and promote relaxation in pediatric patients. The video immerses participants in a calming virtual environment with interactive and visually engaging content tailored for children. It is administered prior to the endoscopy procedure to help manage anxiety and stabilize vital signs, such as blood pressure, heart rate, and oxygen saturation. The VR session serves as a non-pharmacological approach to anxiety management during medical procedures.
Study NCT06772025 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No investigational study intervention
Description: No investigational study interventions will be administered in this study. Participants will undergo therapeutic and diagnostic procedures as per local standard medical care and as deemed appropriate by the treating physicians. Collection of blood (not exceeding 150 mL) and urine samples and of available clinical data are the only activities performed in addition.
Study NCT06772324 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NORSPAN Buprenorphine Transdermal Patchs for Very-low dose group
Description: Very-low dose group will receive medication on arrival before completing the relevant assessment tests; the very-low dose group will be administered 1/9 of a 5mg buprenorphine transdermal patch and replaced with a 0mg patch before returning home from the examination.
Study NCT06772324 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NORSPAN Buprenorphine Transdermal Patchs for Lower dose group
Description: The lower dose group will be administered 1/9 of a 5mg buprenorphine transdermal patch.
Study NCT06772324 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NORSPAN Buprenorphine Transdermal Patchs for higher dose group
Description: The higher dose group will be administered 1/3 of a 5mg buprenorphine transdermal patch.
Study NCT06773559 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: plantar pressure, gait and static balance analysis
Description: Plantar pressure, gait and static balance analysis performed using Ultium Insole SmartLead insoles.
Study NCT06773559 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: trunk posture analysis
Description: Trunk posture analysis was performed using Diers Formetric 4D.
Study NCT06770231 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Single drill system
Description: New system for drilling
Study NCT06770231 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single drill system
Description: New system for drilling
Study NCT05006300 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Topialyse Baume Barrière
Description: Evaluation of the efficacy of the cosmetic product SVR TOPIALYSE Baume Barrière on the reduction of topical corticosteroid consumption in children from 3 months to 17 years old presenting mild to moderate atopic dermatitis after 28 and 56 days of use, at one or two apllications /day.
Study NCT05740956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10502
Description: HS-10502 will be administered once per day on a continuous dosing schedule starting on Cycle 1 Day 1 (C1D1) in a 28-day treatment cycle.
Study NCT06774157 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A session combining motor imagery and listening to low frequency sounds
Description: Prospective study of the efficacy of the Allyane procedure after knee sprain
Study NCT06774157 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical therapy including exercises
Description: Active extension (e.g. by lateral raising of the quadriceps, strengthening of the quadriceps) quadriceps);~* Flexor inhibition (e.g. massage, hamstring stretching);~* Active flexion (e.g. strengthening the flexors)
Study NCT05613413 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cabozantinib 40 MG
Description: Cabozantinib is taken my mouth
Study NCT05613413 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 200mg
Description: Pembrolizumab is given intravenously
Study NCT05613413 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 400mg
Description: Pembrolizumab is given intravenously
Study NCT03981432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-Fixed
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive a fixed meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
Study NCT03981432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REST-AdLib
Description: condition without exercise / rest condition. The participants will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
Study NCT03981432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EX-AdLib
Description: condition with an acute exercise set 30 minutes before the lunch meal that will be served ad libitum This will be a 30-minute exercise set at 65% of their capacities (cycling), 30 minutes before lunch.
Study NCT05452967 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Distraction technique
Description: The post operative pediatric patients will be given mobile phone in recovery for plying games and watching cartoons and with the help of this distraction technique will assess that routine rescue analgesia is needed or not
Study NCT05410288 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acu-TENS
Description: A TENS stimulator will be used (NeuroTrac TENS; Verity Medical Ltd., Wexford, Ireland). Electrodes will be placed over selected acupoints (i.e., bilateral SP6, PC6 and HT7) and connected to the TENS stimulator. These acupoints are selected according to the traditional Chinese medicine and results of previous studies. The stimulation will be lasted 30-min for each session. The frequency of the stimulation parameter's waveform will be set to 100 Hz and the square pulses will be set to 0.2-ms. The intensity of the stimulation will be below motor threshold and lower than the intolerable level, and hence, participants will feel a pleasant and mild aching sensation.
Study NCT05410288 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: acupressure+SHP
Description: Participants in the acupressure group will receive acupressure coupled with SHP. The acupressure protocol was developed based on a protocol recommended by a review and will comprise the following: (1) applying consistent finger-tip pressure of 3-5 kg, with rotational movements; (2) counterclockwise and then clockwise circular motions for 2.5-min each; (3) confirming the precision of the acupressure based on participants feeling pain, numbness, distension, or warmth at the point of application; and (4) an acupoint sequence from the leg to the head, first on the left side of the body and then on the right side of the body; and (5) a 5-min treatment on each acupoint (i.e., bilateral SP6, PC6, and HT7) in each 30-min session. The SHP is the same with Acu-TENS+SHP group.
Study NCT05410288 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo stimulation+SHP
Description: Participants in the placebo stimulation + SHP group will receive 30-minute placebo stimulation from identical-looking TENS devices with the electrical circuit disconnected inside.
Study NCT05410288 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sleep hygiene program(SHP)
Description: SHP is a set of instructions designed to help with sleep and promote healthy sleeping habits. The sleep guide contains information on how much sleep is needed by every individual daily, factors that could affect sleep, and risk factors for sleep disorders. It also contains information on the types of sleep disorders, delayed sleep syndrome, insomnia-producing behavior that could affect sleep quality, and suggestions for inducing sleep. The participants will be instructed to read the guide after the baseline assessment (T0). Those instructions will be reinforced by the research practitioner after each treatment session, in order to maintain the healthy sleeping habits.
Study NCT05410288 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: sleep hygiene program(SHP)
Description: SHP is a set of instructions designed to help with sleep and promote healthy sleeping habits. The sleep guide contains information on how much sleep is needed by every individual daily, factors that could affect sleep, and risk factors for sleep disorders. It also contains information on the types of sleep disorders, delayed sleep syndrome, insomnia-producing behavior that could affect sleep quality, and suggestions for inducing sleep. The participants will be instructed to read the guide after the baseline assessment (T0). Those instructions will be reinforced by the research practitioner after each treatment session, in order to maintain the healthy sleeping habits.
Study NCT04779151 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: Substance: immunoglobulin G4 (IgG4) humanized monoclonal antibody (mAb) that binds with high affinity to PD-1 Manufacturer: Tesaro Inc. Dose: 500 mg every 21 days for the first 4 cycles, followed by 1,000 mg every 42 days cycle (ie, Q6W)
Study NCT04779151 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: Substance: Inhibitor of poly-adenosine diphosphate \[ADP\] ribose polymerase (PARP) Manufacturer: Tesaro Inc. Dose: Flat-fixed dose (if \<77kg or platelets \<150,000 μL: 200mg; if >/=77kg and platelets >/= 150,000μL: 300mg)
Study NCT04869267 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment Therapy (ACT)
Description: Session 1:~This session aims to let the participants get familiar with the interventionist. The interventionist will tell them the purpose of the program and basic rules. And the interventionist will promise their privacy protection.~Session 2:~This session includes how to separate thoughts/feelings/sensations related to diagnose with advanced lung cancer and experience of fatigue with facts and see these feelings in an objective way with observing self.~Session 3:~This session mainly aims to help participants understand the importance of values, differentiate values from goals and clarify their personal values.~Session 4:~This session aims at helping patients practice to engaging in committed action based on chosen values, motivated to change behavior in consistency with life direction and health goal.
Study NCT04869267 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: The usual care mainly includes treatments and daily care during admission, medication instructions, diet and exercise advice, retest recommendations when discharge
Study NCT06349057 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: reducing anticholinergic burden
Description: In the intraoperative and postoperative periods instead of drugs with high anticholinergic burden; drugs with low burden will be preferred.
Study NCT04388501 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Milvexian
Description: Participants will receive milvexian capsules orally qd for 5 days as per the assigned treatment sequence.
Study NCT04388501 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Participants will receive atorvastatin tablets orally qd for 5 days as per the assigned treatment sequence.
Study NCT05202145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN2050
Description: Oral tablet.
Study NCT05202145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclosporine
Description: Oral capsule.
Study NCT05202145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Oral capsule.
Study NCT05202145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MMF
Description: Oral tablet.
Study NCT04805086 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MON002
Description: Autologous monocytes
Study NCT06020235 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.
Study NCT06020235 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 10% Nu-3 gel
Description: The gel is called Nu-3 which is either applied once per day or twice per day to the infected ulcer.
Study NCT06020235 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo gel is either applied once per day or twice per day to the infected ulcer.
Study NCT06020235 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo gel is either applied once per day or twice per day to the infected ulcer.
Study NCT06361641 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Monocytes signatures in myeloproliferative neoplasms at diagnosis
Description: The monocytes signatures will be perform from a peripheral blood sample. The signature will be derived from (i) surface marker expression, (ii) cytokines profiles, (iii) genes expression.
Study NCT05772897 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Circle of Security Parenting program
Description: The Circle of Security Parenting (COSP) program is an 8- week group parenting course that was designed using decades of attachment research to foster a secure attachment by teaching parents to read and respond to infant cues, and to recognize the interplay between their own psychological and emotional experiences and the emotional regulation of their infants. The COSP program provides parents with relationship tools and techniques for understanding their children's needs in new ways that provide lasting security for the child and more satisfaction for the parent. There are two major themes in the program: 1) teaching parents how to read their children's behavior and use it as a guide for meeting their needs and 2) helping parents to understand how their own early attachment relationships have influenced them as a person, and how those influences show up in their parenting and impact their ability to help regulate their child and respond to their needs.
Study NCT06488261 — intervention group
Intervention type: BIOLOGICAL
Intervention: AVR-RD-02
Description: No study drug is administered in this study. Subjects who received AVR-RD-02 in a separate parent trial will be evaluated in this trial for long-term safety.
Study NCT04728490 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Allogenic transplantation transplantation
Description: Haplo-identical transplantation with the use of Treosulfan, Thiotepa and Fludarabine in conditioning regimen.
Study NCT05434039 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: diclofenac phonophoresis
Description: the patients will be in comfortable position and apply diclofenac phonophoresis on upper trapezius and suboccipital muscle by ultrasound device. diclofenac gel was applied circularly with a thickness of 2-3 mm. Then ultrasound with was applied with 1 MHz frequency and 1.5 Wt/cm2 power over the trigger points on the trapezius and suboccipital muscle, for 10 min.
Study NCT05434039 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high power pain threshold ultrasound
Description: the patients will be in comfortable position and The frequency was set to 1 MHz, and the intensity will be increased from 0.5 to 2 until the patient reported an unpleasant sensation. The probe was held there for 4 s; then, the intensity was reduced by 50%, and the probe will be moved over and around the trigger point. This process is done several times for three minutes
Study NCT05434039 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: the patient will receive an active range of motion exercise, stretching and strengthening of all cervical muscles
Study NCT05434039 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional therapy
Description: the patient will receive an active range of motion exercise, stretching and strengthening of all cervical muscles
Study NCT06770205 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional physical therapy
Description: hot pack and TENS for 10 minutes and massage that will as 3 sessions per week for 4 weeks.
Study NCT06770205 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kendall Exercise Group A
Description: The group B will receive Proprioceptive Neuromuscular Facilitation technique for stretching and rhythmic stabilization technique for strengthening. Proprioceptive Neuromuscular Facilitation (PNF) is a stretching technique utilized to improve muscle elasticity and has been shown to have a positive effect on active and passive range of motions. The PNF group performed the intervention for 30 minutes a day, six times a week, a total of 24 times. (13) In this group, two types of PNF techniques were given:~1. first is strengthening technique included rhythmic stabilization that is characterized by alternating isometric contractions against resistance, no motion intended to apply for the weak muscles of upper cross syndrome included deep neck flexors specifically lower trapezius and serratus anterior.~2. Second is stretching technique included contract relax that is resisted isotonic contractions of the restricting muscles (antagonists) followed by relaxation and movement
Study NCT04506983 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GPC3-CAR-T cells
Description: Patients with hepatocellular carcinoma will be enrolled, and GPC3-CAR-T cells will be intravenously infused with a escalated dose of 1×106 /3×106/10×106GPC3-CAR-T cells.
Study NCT06773676 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: B-Cure laser pro
Description: The B-Cure laser pro is a portal, non-invasive, photobiomodulation device, that emits light in the near infrared (808nm) over an area of 1X4.5 cm2 with power output of 250mW, and energy dose of 1J/cm2.
Study NCT06773676 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: The sham device is externally identical to active, emits the same guiding light and sound but does not emit the therapeutic near infrared invisible rays
Study NCT06348082 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based therapy for insomnia (MBTI)
Description: MBTI will be administered in 8 weekly sessions. Session 1 consists of introductions and an overview. Subsequent sessions consist of mindfulness concepts/practice and behavioral strategies for sleep. Each session will begin with guided formal meditation followed by discussion. Mindfulness practice (at home) expectations are 30-45 minutes of meditation/day at least 5 days during the period of the intervention, followed by 20 minutes/day until the final follow-up assessment (at 16 weeks). Mindfulness concepts: Overview of Mindfulness, Mindfulness of the Body, Obstacles to Mindfulness,Working with Difficult Emotions, Cultivating Positive Emotions, Working with Difficult Thoughts, Mindful Interactions.
Study NCT05406856 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: External beam radiation therapy: IMRT/VMAT
Description: EBRT is given to a total dose of 45 Gy in 25 daily fractions of 1.8 Gy in 5 weeks. Involved nodes are boosted using a simultaneous integrated boost (SIB) to reach a total EBRT plus brachytherapy dose of 60 Gy EQD2 to provide high nodal control.
Study NCT05406856 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: External beam radiation therapy: IMPT
Description: EBRT is given to a total dose of 45 Gy in 25 daily fractions of 1.8 Gy in 5 weeks. Involved nodes are boosted using a simultaneous integrated boost (SIB) to reach a total EBRT plus brachytherapy dose of 60 Gy EQD2 to provide high nodal control.