AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06584695 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transversus abdominis plane block
Description: Patients will receive transversus abdominis plane block with an oblique subcostal approach in the supine position. The anesthesiologist will place the linear ultrasound transducer obliquely on the upper abdominal wall along the subcostal margin near the xiphisternum of the sternum in the midline of the abdomen. The anesthesiologist will direct a 22G, 80 mm needle toward the transversus abdominis fascia and inject 25 mL of 0.25% bupivacaine between the rectus abdominis and transversus abdominis muscles along the subcostal line.
Study NCT06584695 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: External Oblique Intercostal Plane Block
Description: Patients will receive external oblique intercostal block the patient will be in the supine position with their ipsilateral arm abducted, A linear ultrasound transducer will be placed in the sagittal plane between the midclavicular and anterior axillary lines at the level of sixth rib, with the orientation marker directed cranially. The skin will be sterilized, and the probe will be placed over the sixth rib medial to the anterior axillary line in a parasagittal orientation the in-plane technique with a 22G, 80 mm block needle will be used to inject 25 ml of 0.25% bupivacaine into the external oblique intercostal plane.
Study NCT06584695 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: Patients will receive IV morphine 0.1mg/kg after induction of general anesthesia.~General anesthesia induction will be performed with fentanyl 1-2 μg/kg, propofol 2-3 mg/kg, and rocuronium 0.6 mg/kg and maintained with sevoflurane.
Study NCT04982250 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Formal peer PrEP referral + HIVST delivery
Description: After a brief training, young female PrEP users will be encouraged to refer up to 4 peers to PrEP using strategies gained from the training, PrEP educational materials (i.e., brochures), HIVST kits (2 kits/peer = 8 kits total), and Kenya MOH-style referral cards.
Study NCT05101096 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan-hziy
Description: Administered intravenously (IV)
Study NCT06262412 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-delivered cognitive-behaviour therapy (ICBT)
Description: The intervention is Internet-delivered and therapist-guided, involving both the adolescent and at least one caregiver. It consists of two separate sets of modules, one for the adolescent and one for the caregiver. The intervention consists of 12 modules, delivered over a maximum of 14 weeks.~The first part includes psychoeducation about BDD and strategies to resolve possible ambivalence towards psychological treatment. The main goal of the treatment is to help the young person to stop avoiding anxiety-provoking situations (e.g., going to school or participating in social situations) by undertaking exposure tasks and to stop doing unhelpful repetitive behaviours and rituals (e.g., excessive mirror-checking, camouflaging), known as response prevention. Every module also contains homework tasks that are meant to be completed between modules and mainly consist of exposure and response prevention (ERP) tasks based on the young person's individual goals.
Study NCT06262412 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet-delivered relaxation treatment (IRT)
Description: The intervention is Internet-delivered and therapist-guided, involving both the adolescent and at least one caregiver. It consists of two separate sets of modules, one for the adolescent and one for the caregiver. The intervention consists of 12 modules, delivered over a maximum of 14 weeks.~The first part includes psychoeducation about BDD, how anxiety and stress are major contributors to BDD symptoms, and that targeting and reducing stress will have a beneficial impact on those symptoms. The main goal of the treatment is to teach the young person to relax in order to cope with anxiety and appearance concerns. The intervention mainly consists of a relaxation treatment and includes different relaxation skills such as deep breathing, progressive muscle relaxation, and imagery (cognitive relaxation). Every module also contains homework tasks that are meant to be completed between modules and mainly consist of relaxation tasks.
Study NCT06551610 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Triage Tool
Description: Tool that uses patient characteristics to triage patients for an earlier procedure date vs the standard of care 12 week wait for procedure.
Study NCT05849831 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound measurement of Optic nerve sheath diameter
Description: Ocular ultrasonography will be performed by single skilled examiner with patients placed in supine position with closed eyes. A layer of ultrasound gel will be applied over the closed upper eyelid and the liner high frequency probe 7 - 12 MHz of SonoSite M-Turbo ultrasound machine is placed on temporal area of eyelid with the hand holding it resting on forehead of patient. ONSD is measured 3mm behind the globe in the transverse plane perpendicular to the optic nerve. For each eye one measurement will be made and the reported ONSD corresponds to the mean of the two values obtained for each patient. An average ONSD greater than 5 mm is considered abnormal and elevated intracranial pressure should be suspected. all enrolled subjects will be eligible for ONSD measurements, SOFA score calculation, as well as GCS assessment on daily basis for up to 10 consecutive days, until ICU discharge or death.
Study NCT06199570 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adapted Stress Management Program
Description: Participants will receive a 15-minute orientation session in-person or remotely to introduce the program and to receive the study materials, including the instructional sheet, small booklet, and study tablet that will be used to promote practice of stress management exercises and for completing study assessments. They will complete self-guided web modules with stress management activities/skills on tablet devices, and will rate the modules' acceptability and perceived helpfulness. After visiting each module, they will be asked to practice at least one skill daily. In a 1-week pre-scan call, they will be reminded about the skills, make a plan for using them, and troubleshoot questions about using the materials. Participants will attend scans and scan result appointments with their oncologist as usual. In a 1-week post-scan phone call, the stress management plan will be revisited for new concerns.
Study NCT06199570 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Enhanced usual care includes a resource list, tablet for study assessments, and reminder calls.
Study NCT06306599 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: S-Detect for Thyroid
Description: Deep learning based program on Samsung ultrasound machines designed to do real-time semi-automated analysis of thyroid nodules. The ultrasound operator freezes a transverse image of the patient's thyroid nodule and activates S-Detect. The operator selects the nodule on the screen, and the program automatically draws a region of interest. Then S-Detect gives a dichotomous diagnosis of either Possibly benign and Possibly malignant. In addition, it measures the nodule and characterises it with a lexicon based on EUTIRADS.
Study NCT05668351 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SUPR-SABR treatment
Description: SUPR-SABR prescription dose to the PTV_4000 will be 8 Gy per fraction for five fractions. The prescription dose to PTV_3625 will be a minimum of 7.25 Gy per fraction for five fractions. SABR will be delivered 2-3 times a week, every other day. There will be a minimum of 40 hours between fractions and maximum of 128 hours between fractions.
Study NCT05532150 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic Bankart repair
Description: Participants in this group will undergo minimally invasive surgery to repair their shoulder with a technique called a Bankart repair.
Study NCT05532150 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Physical therapy
Description: Participants in this group will follow a specific physical therapy rehabilitation protocol
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Radio Ads
Description: Engaging radio mini shows that address community stigma and medical literacy through busting common myths with humor and building empathy with heartfelt storytelling.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Radio Ads
Description: Engaging radio mini shows that address community stigma and medical literacy through busting common myths with humor and building empathy with heartfelt storytelling.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Sensitization Campaign
Description: Large-scale, infographic billboards and posters located in public areas and secondary schools to address stigma, medical literacy and promote community support for AYAHIV.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Community Sensitization Campaign
Description: Large-scale, infographic billboards and posters located in public areas and secondary schools to address stigma, medical literacy and promote community support for AYAHIV.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Informational Posters
Description: Large-scale, infographic posters located in clinic waiting areas to normalize HIV and build confidence in treatment.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Informational Posters
Description: Large-scale, infographic posters located in clinic waiting areas to normalize HIV and build confidence in treatment.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivation Walls
Description: Interactive, patient-generated posters located in the consultation room where patients can post words and phrases about themselves and their futures.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Motivation Walls
Description: Interactive, patient-generated posters located in the consultation room where patients can post words and phrases about themselves and their futures.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pill Container
Description: A discreet pill container to support ART adherence.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pill Container
Description: A discreet pill container to support ART adherence.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CombinADO-specific training for healthcare workers
Description: Comprehensive in-service training for healthcare workers focused on the needs of adolescents and young adults living with HIV
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CombinADO-specific training for healthcare workers
Description: Comprehensive in-service training for healthcare workers focused on the needs of adolescents and young adults living with HIV
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: One Stop Shop Model of Care
Description: Model of care that allows adolescents and young adults living with HIV to access a complete set of services, including HIV care, in one central location.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: One Stop Shop Model of Care
Description: Model of care that allows adolescents and young adults living with HIV to access a complete set of services, including HIV care, in one central location.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment Toolkit
Description: A guide to clinic visits and discussions on ART and viral load monitoring to help healthcare workers better communicate with patients.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment Toolkit
Description: A guide to clinic visits and discussions on ART and viral load monitoring to help healthcare workers better communicate with patients.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-reflection Kit
Description: A simple handout for healthcare workers to help patients reflect on their ART progress and understand the concept of viral load as a measure of ART success.
Study NCT04930367 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Self-reflection Kit
Description: A simple handout for healthcare workers to help patients reflect on their ART progress and understand the concept of viral load as a measure of ART success.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Support
Description: Peer exposure to examples of adolescents and young adults openly living with HIV (AYAHIV) and; opportunities to share their experiences with HIV in one-on-one interactions with other AYAHIV during clinic visits.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Informational and motivational Video
Description: An informational and motivational video that in simple language with engaging graphics that a) demystifies and simplifies HIV, ART, and viral load and; b) emphasizes that people can live long, healthy lives.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support groups- caregivers of adolescents and young adults living with HIV
Description: A learning, support, and empowerment group for caregivers of adolescents and young adults living with HIV (AYAHIV). Through monthly gatherings, the program aims to foster confidence, and equip caregivers with strategies to support AYAHIV adherence journey.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Support groups- adolescents and young adults living with HIV
Description: A peer-to-peer learning, support, and empowerment group to address loss of hope and improve medical literacy. Through biweekly gatherings, the program aims to foster belonging and confidence, equipping young people and caregivers with strategies to navigate the adherence journey.
Study NCT04930367 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental health screening and linkage to adolescent-focused mental health support
Description: HCWs will be trained in the use of a brief mental health screening tool focusing on depression, anxiety, and post-traumatic stress disorder. Mental health service providers at each facility will be trained and supported to provide diagnostic and mental health support to youth with positive screens who agree to further evaluation.
Study NCT05640830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: trastuzumab, bevacizumab with paclitaxel (triple combination)
Description: Trastuzumab 4 mg/kg Day 1, 15 Bevacizumab 5 mg/kg Day 1, 15 Paclitaxel 80 mg/m2 Day 1, 8, 15 every 4 weeks
Study NCT06356922 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental drug [177Lu]Lu-PentixaTher
Description: Injection of \[177Lu\]Lu-PentixaTher
Study NCT06594718 — intervention group
Intervention type: PROCEDURE
Intervention: Endoscopic diverticulotomy with Z-POEM
Description: Endoscopic diverticulotomy with Z-POEM
Study NCT06594718 — intervention group
Intervention type: PROCEDURE
Intervention: Endoscopic diverticulotomy using a non-tunnelization technique
Description: Endoscopic diverticulotomy with diverticuloscope, Knife Septotomy, or Clutch Cutter
Study NCT06590779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aminexil® active+ lotion
Description: Aminexil® active+ lotion
Study NCT06590779 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Finasteride 1mg
Description: Finasteride 1 mg
Study NCT06590779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Finasteride 1mg
Description: Finasteride 1 mg
Study NCT06599112 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Densah Burs
Description: Series of drilling burs inserted in the osteotomy with special design that have a large negative rake angle flute, a cutting chisel edge and a tapered shank, so as they enter deeper into the osteotomy and they have a progressively increasing diameter that controls the expansion process. These burs are used with a standard surgical engine and can densify bone by rotating in the noncutting direction (counterclockwise at 800-1,200 rotations per minute) or drill bone by rotating in the cutting direction (clockwise at 800-1,200 rotations per minute) with an in and out movement together with copious saline irrigation and increasing bone plasticity and ability to expand under rate dependent stress.
Study NCT06599112 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteotomes
Description: The osteotomes kit are a series of tools that first designed by Summers in 1994. The concept was to maintain the existing bone by compressing trabecular bone laterally and apically with minimal trauma to improve the bone density. The condensed bone in this way will have to put in act a double repairing mechanism, from one side represented by the normal processes of osteointegration and on the other side from the processes of the reparation post fracture like that depends on BMU (bone modelling units) which create new spaces for the new vessels and afterwards filling all the gaps between the bone and the implant.
Study NCT06599112 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional drilling
Description: The implant drilling kit provided by the manufacturer will be used for the implant placement, using the pilot drill followed by consequent drills according to the size of the osteotomy needed.
Study NCT06601673 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive training
Description: The intervention consists of computer-based cognitive training in the areas of attention, processing speed, memory, emotional intelligence, reasoning and orientation. The training takes place under supervision for 120 minutes a day from the first to the fifth postoperative day.
Study NCT06601673 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Listen to audio book
Description: Here, an audio book is listened to for 2h daily for the first five postoperative days (or until discharge from hospital if earlier). The audio book is brought and set up by study staff.
Study NCT06592092 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: QH104 Cell injection
Description: Patients will first be pre-screened for B7H3 expression of tumor and exist Meningeal Metastases.
Study NCT06593145 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FCTX-CL19-1 (Tarcidomgen Kimleucel)
Description: It will be administered only by Investigators during hospitalization. Each patient will receive one administration of IMP on Day 0:~* administration route - intravenous~* cell dose: 0,2 x 106 -2 x 106 CAR T cells per kilogram of patient body weight
Study NCT06601491 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Intervention
Description: Participants in the intervention group receive structured, pesonalised lifestyle, dietary and physical activity consultations. They undergo various assessments such as aortic stiffness measurement, blood pressure measurement, and complete several questionnaires (e.g., whole exome sequencing, IPAQ, handgrip strength, socio-demographic, clinical history, quality of life, smoking, alcohol consumption, sleep patterns, stress assessment).
Study NCT06598969 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Total bone marrow and lymphoid irradiation/cyclophosphamide/etoposide
Description: Evaluate the antileukemic activity of an total bone marrow and lymphoid irradiation/cyclophosphamide/etoposide conditioning regimen for allogeneic hematopoietic stem cell transplantation
Study NCT06586385 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: disaster education
Description: The ADDIE Instructional Design Model will be used due to its suitability for adult education. General Disaster Awareness Training will be prepared according to the ADDIE instructional design model, which consists of five stages: analysis, design, development, implementation and evaluation. The trainings to be given will be given 1 week after the pre-test, 1 training per week, for a total of 3 trainings.
Study NCT05607446 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQC3564 tablets
Description: TQC3564 tablets are CRTH2 antagonists.
Study NCT05607446 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablets
Description: The intervention drug is placebo.
Study NCT05607446 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQC3564 tablets, montelukast sodium tablets
Description: The intervention drugs are TQC3564 tablets combined with montelukast sodium tablets. TQC3564 is a CRTH2 antagonist, montelukast sodium is Leukotriene receptor antagonist.
Study NCT05607446 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablets, montelukast sodium tablets
Description: The intervention drugs are placebo combined with montelukast sodium tablets. Montelukast sodium is Leukotriene receptor antagonist.
Study NCT06070766 — intervention group
Intervention type: DRUG
Intervention: Ketamine
Description: The use of ketamine in chronic conditions.
Study NCT06594380 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group using new oropharyngeal airway (experimental group)
Description: Before anesthesia induction, study participants in the experimental group received 5-6L/min oxygen for about 1min through an endoscopic bite oxygen supply device, and anesthesia induction was administered with propofol 3mg/kg and sufentanil 7μg.Sufentanil was given at the beginning of pre-oxygen inhalation, and propofol was given 1min later. When participants achieved sufficient sedation (about BIS40), they were placed into the oropharyngeal airway through the endoscopic bite and began gastroscopy.Anesthetic maintenance was administered with a continuous pump of 5mg/kg·h propofol until completion of the examination