AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05912309 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Caloric Restriction
Description: Individualised intensive behavioural intervention weight loss program including CR, exercise training and lifestyle education designed according to the current guidelines. CR will be tailored to participants (objectively assessed). Diet will provide 600 kcal/day less than the individual energy requirements based on measured resting energy expenditure (indirect calorimetry) and multiplied by an activity factor obtained by accelerometry. Experienced nutritionists will design personalized and balanced CR diet, and will train the participants through the food exchange system to follow the treatment. In those cases in which the CR compromised a protein intake of at least 1.2 g/kg/day, the macronutrient percentage distribution will be modified prioritizing achieving this minimum protein intake.
Study NCT05534893 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Blueberry powder group
Description: Participants in the blueberry powder group will receive freeze dried blueberries in form of a powder
Study NCT05534893 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Blueberry powder group
Description: Participants in the blueberry powder group will receive freeze dried blueberries in form of a powder
Study NCT05580471 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use 4DryField
Description: Patients randomly use 4DryField in Colorectal resection combined with temporary stomy before fascia closure. We observed the adhesion severity and adhesion extent when stomy closure.
Study NCT05534893 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo powder group
Description: Participants in the placebo powder group will receive an isocaloric placebo powder
Study NCT05534893 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo powder group
Description: Participants in the placebo powder group will receive an isocaloric placebo powder
Study NCT02637986 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Urex Plus - containing L. rhamnosus GR-1 and L. reuteri RC-14
Description: 2 capsules will be given per day
Study NCT05254314 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide Pen Injector 2.4mg weekly
Description: Once weekly subcutaneous injection
Study NCT05254314 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Once weekly subcutaneous injection
Study NCT06068322 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training on a stationary bicycle
Description: Training is performed two to three times per week for a total of 30 sessions using a group format.~Both regimens start with a five-minute warm-up and ends with a five-minute cool-down, performed at an intensity corresponding to 30% of the maximal work rate achieved during a CPET (i.e., max aerobic power \[MAP\]) with a self-selected pedalling cadence of 50-70 revolutions per minute (RPM).~All exercise sessions will be held and supervised by an experienced health care professional, i.e. physiotherapists or other health professional.~The different types of exercise training is described under the specific arm.~Following the first 12-week training period, participants with COPD will enter a 21-month maintenance phase. They will continue to exercise using the same training modality (HIIT or MICT) as during the first 12-weeks but can select between three different settings to continue their training: Home, Outpatient, or Mix setting.
Study NCT06068322 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training on a stationary bicycle
Description: Training is performed two to three times per week for a total of 30 sessions using a group format.~Both regimens start with a five-minute warm-up and ends with a five-minute cool-down, performed at an intensity corresponding to 30% of the maximal work rate achieved during a CPET (i.e., max aerobic power \[MAP\]) with a self-selected pedalling cadence of 50-70 revolutions per minute (RPM).~All exercise sessions will be held and supervised by an experienced health care professional, i.e. physiotherapists or other health professional.~The different types of exercise training is described under the specific arm.~Following the first 12-week training period, participants with COPD will enter a 21-month maintenance phase. They will continue to exercise using the same training modality (HIIT or MICT) as during the first 12-weeks but can select between three different settings to continue their training: Home, Outpatient, or Mix setting.
Study NCT04876599 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IN FOCUS
Description: Adapted Resiliency Group Intervention
Study NCT04876599 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Referral to Virtual Group Support
Study NCT05093257 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Laboratory investigations for control
Description: 1. Complete blood picture .~2. Erythrocyte sedimentation rate(ESR).~3. Liver function tests .~4. Kidney function tests.~5. CD3, CD4,CD8,CD16,CD56 from peripheral blood samples by Flowcytometry
Study NCT05093257 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Laboratory investigations for patients
Description: 1. Complete blood picture .~2. Erythrocyte sedimentation rate(ESR).~3. Liver function tests .~4. Kidney function tests.~5. Anti-nuclear antibodies test by immunoflourescence for ITP patients.~6. Bone marrow aspiration (for diagnosis of ITP).~7. CD3, CD4,CD8,CD16,CD56 from peripheral blood samples by Flowcytometry.
Study NCT04727606 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ure-Na
Description: * Participants in the study will receive Oral Urea (Ure-Na) treatment at a dose of 30 grams per day (2 x 15 gram pouches per day)~* Treatment will continue for approximately 1 month.
Study NCT05402098 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endodontic treatment using traditional access
Description: Endodontic treatment will be carried out following complete removal of pulp chamber roof and achieving straight line access
Study NCT05402098 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endodontic treatment using conservative access
Description: Endodontic treatment will be carried out following partial removal of pulp chamber roof, extended only to the extent which helps to locate all the orifices with no efforts will be made to achieve straight line access
Study NCT06155877 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activité Vaccins et Vaccination - LAMAP
Description: Two activities created by the La Main a la Pate foundation
Study NCT06155877 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kidivax Chatbot
Description: A chatbot created by our team to answer the most common questions about vaccination, based on a literature review and on focus groups.
Study NCT06405698 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical closure of myelomeningocele defects by perforator-plus flaps
Description: closure of myelomeningocele defect by perforator-plus island flap harvesting leaving skin bridge connecting to the flap and dissection of the perforator vessel
Study NCT05638841 — intervention group
Intervention type: OTHER
Intervention: After radiofrequency ablation of atrial fibrillation
Description: This study imposed an intervention. Clinical data were obtained by telephone or outpatient follow-up.
Study NCT04798365 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention group
Description: medical education and distribution of educations materials
Study NCT04860765 — intervention group
Intervention type: DEVICE
Intervention: SAPIEN 3 THV
Description: SAPIEN 3 THV in the pulmonic position
Study NCT05318209 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Closed-chain Shoulder Girdle Scapular Depression Exercise
Study NCT05318209 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Closed-chain Shoulder Girdle Scapular Depression Exercise
Study NCT06026774 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: iNeo-Vac-R01 in combination with standard adjuvant therapy
Description: Personalized mRNA vaccine encoding neoantigen, IH injection
Study NCT05800145 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resource information Supplemental Nutrition Assistance Program (SNAP)
Description: Participants randomized to the resource referral arm will receive a tailored list of information about community resources. The list will include information about local emergency food resources (e.g. local food pantries) and government programs to address FI (e.g. SNAP).
Study NCT05800145 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: community health worker (CHW)
Description: Participants randomized to the CHW intervention will have an initial baseline visit scheduled at a mutually convenient location.
Study NCT05800145 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: medically tailored meals
Description: Participants will receive 10 medically tailored meals delivery to their home weekly for 3 months
Study NCT06496074 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Head-up Tilt Test
Description: Two protocols for the head-up tilt test (HUTT) are used in our center and in the collaborating centers: (1) passive or prolonged inclination protocol \[40 minutes\], (2) mixed protocol: passive phase \[first 20 minutes\] plus nitrate-provoked phase \[last 20 minutes\], with the use of 1.25 mg sublingual isosorbide dinitrate. All patients are submitted to 10 minutes of rest in the supine position at zero degree before the tilt phase of the HUTT. During this period, HR and systolic (SBP) and diastolic (DBP) measurements are obtained every 2 minutes. After this phase, the table is tilted at an angle of 70° with measurement of SBP / DBP and HR every minute. Patients older than 60 years are routinely investigated for carotid sinus hypersensitivity by carotid sinus massage during the passive phase of the HUTT. The exam is considered positive according to the criteria defined in guidelines.
Study NCT05492370 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: EpiCor
Description: 2 gummies daily
Study NCT05492370 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 gummies daily
Study NCT04601038 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: CORT108297
Description: 120mg of a selective glucocorticoid receptor antagonist, taken as 2 tablets daily for 2 weeks
Study NCT04601038 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: Placebo taken as 2 tablets daily for 2 weeks
Study NCT05123677 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Non-invasive haemodynamic assessment
Description: Maternal non-invasive haemodynamic assessment: a pressure cuff (similar to the one used to measure blood pressure) is applied to the arm and thigh, and a further neck sensor applied. Information about the function of heart and major blood vessels are recorded
Study NCT05123677 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Maternal ophthalmic artery doppler
Description: Maternal ophthalmic artery doppler: an ultrasound probe is applied gently over the eyelid for a few seconds to study the blood flow of the main artery to the eye
Study NCT02637986 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo - capsule with no active ingredient
Description: 2 capsules will be given per day
Study NCT05900271 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: rTMS
Description: 10 Hz repetitive-transcranial-magnetic-stimulation
Study NCT06438991 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adjustment of spinal cord stimulation parameters for voluntary motor control
Description: All patients will receive a spinal cord stimulator and undergo adjustment of stimulation parameters for optimal voluntary lower extremity motor control during research visits. Muscle strength will be assessed with the stimulation turned on and off.
Study NCT06078475 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Postoperative analgesia management
Description: Patients will be administered paracetamol 1 gr (PERFALGAN® ) IV every 8 hours in the postoperative period.. If the patient's NRS score is ≥ 4 0,5 mg/kg IV meperidine (Aldolan ampul 100 mg/2 ml) will be administered.
Study NCT05525910 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nirmatrelvir/ ritonavir
Description: Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Study NCT05525910 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir/ritonavir
Description: Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Study NCT05525910 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir/ ritonavir
Description: Single oral dose of nirmatrelvir/ritonavir tablets under fasted condition
Study NCT05685303 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alleviant ALV1 System
Description: Creation of interatrial shunt
Study NCT05685303 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham-Control
Description: Cardiac imaging
Study NCT05030467 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REDUCE-BP Intervention
Description: Pre-visit:~Providers in the intervention arm will receive dashboards which will highlight racial/ethnic differences in rates of achieving blood pressure control within their patient panel. The dashboard will also provide individual-level information for patients with poorly controlled blood pressure.~During visit:~Providers will receive clinical decision support within relevant patients' charts that highlight the patient's under-treated blood pressure and potential impacts of social needs.~Providers will have the opportunity to provide enhanced patient education materials, which can be automatically ordered within the clinical decision support.~Post-visit:~Patient-subjects' access to the online patient portal will be streamlined by the inclusion of information about the patient portal in the patients' after-visit summary. Providers will also be able to referral patients automatically to nurse BP visits.
Study NCT05419232 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Short Message Service (SMS) + Website Link Strategy
Description: The intervention we are evaluating is the effectiveness of a participant receiving a SMS + Website Link as a vaccine uptake strategy
Study NCT05419232 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Phone Call with Peer Strategy
Description: The intervention we are evaluating is the effectiveness of a participant having a phone call with a peer as a vaccine uptake strategy
Study NCT05275673 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sapanisertib
Description: capsules for oral administration
Study NCT05250037 — intervention group
Intervention type: PROCEDURE
Intervention: Home spirometry
Description: Undergo spirometry measurements
Study NCT05250037 — intervention group
Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo nasal and/or oral swabs, and blood collection
Study NCT05250037 — intervention group
Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study NCT06124222 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prosthetic oral rehabilitation
Description: Prosthetic rehabilitation with fixed and/or removable prosthesis.
Study NCT06124222 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prosthetic oral rehabilitation
Description: Prosthetic rehabilitation with fixed and/or removable prosthesis.
Study NCT05631249 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib 120Mg Tab
Description: Daily sotorasib treatment until progression, unacceptable toxicity, death, or lost to follow-up
Study NCT04375800 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doravirine
Description: DOR capsules (3.2 to 100 mg); sachets (3.2 to 100 mg); or tablets (100 mg) taken once or twice daily by mouth.
Study NCT04375800 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 2 NRTIs
Description: Participants receive 2 NRTIs per local label by mouth for 96 weeks as background therapy.
Study NCT05448950 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VIG Continued Access Study
Description: Small skin incisions will be made for tunneling the graft under the skin in a standard manner. The VIG device is provided pre-loaded within a customized catheter-based delivery system for over-the-wire delivery. The VIG is inserted through an introducer sheath placed in the target vein so that the 'vessel end' of the VIG is deployed within the vein, and the 'graft end' extends out of the vein for connection to the graft. Delivery and deployment will be performed under fluoroscopic guidance. The VIG will be deployed first, connected to the AVG, then the graft and VIG will be flushed and clamped. The arterial anastomosis will then be created using a standard suturing method.
Study NCT04875520 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Screening testing strategy
Description: The intervention we are evaluating is the use of weekly screening testing among students and staff.
Study NCT04875520 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No screening testing strategy
Description: a group of schools will not receive screening testing.
Study NCT05026723 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MTM + ILI
Description: Weekly home meal delivery; an explanation of the medical tailoring of the meals; and a 20-session telephone lifestyle intervention change program
Study NCT05026723 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard MTM
Description: Weekly home meal delivery; an explanation of the medical tailoring of the meals; and an initial consultation with a dietitian
Study NCT06311799 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: WIC Referral
Description: Clinical team will refer study participants to WIC
Study NCT06311799 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: RDN Referral
Description: Clinical team will refer study participants to a RDN
Study NCT05592548 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cold atmospheric plasma
Description: Cold atmospheric plasma will be generated on the skin surface using an electric device
Study NCT05889286 — intervention group
Intervention type: DRUG
Intervention: [F-18]MHF
Description: Following intravenous injection of 10 ± 2 mCi (370 ± 74 MBq) \[F-18\]MHF as a bolus, dynamic PET imaging of the lower limbs will be acquired for approximately 90 minutes. The acquired images will be processed. The uptake pattern of \[F-18\]MHF around infected orthopedic knee implant will be determined and compared with its uptake pattern around non-infected knee implants.
Study NCT05462912 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: custom foot orthotic
Description: The goal of this study is to find out whether the use of software generated custom-made orthopedic foot orthoses improves pain in the long term.
Study NCT05900271 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iTBS
Description: neuronavigated intermittent theta burst transcranial-magnetic-stimulation
Study NCT05404958 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Systems Analysis and Improvement Approach (SAIA)
Description: What is SAIA? It is a 5-step cycle that is repeated every 4-6 weeks for continuous quality improvement, implemented by Kenyan public health workforce and FP clinic staff, and monitored by Mombasa DOH.~Step 1: Understanding the cascade from FP clinic enrollment to HIV testing to linkage to treatment and prevention services.~Step 2: Use process mapping to identify modifiable bottlenecks. Step 3: Define and implement workflow adaptations to eliminate modifiable bottlenecks.~Step 4: Monitor change in performance. Step 5: Repeat the analysis and improvement cycle (steps 1-4).
Study NCT05993377 — intervention group
Intervention type: OTHER
Intervention: Logistic regression Cross validation Area under the RIC curves Machine learning analysis. .
Description: we will use robust machine learning approaches, such as Random Forest and XGBoost.
Study NCT05960799 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CON - Contiplex C™ (CC)
Description: This is a catheter used for peripherical nerve block that is inserted at the same time that the needle is being introduced. When the target is achieved, the needle is retired.
Study NCT05960799 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CTN - Contiplex
Description: This is the traditional catheter used in this centre for peripheric nerve block. In this catheter the needle is introduced first. When the target is achieved the catheter is then introduced throw the needle and after that the needle is retired.
Study NCT05614505 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ready to use therapeutic foods
Description: locally produced therapeutic foods
Study NCT05614505 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ready to use therapeutic foods
Description: locally produced therapeutic foods
Study NCT05207098 — intervention group
Intervention type: OTHER
Intervention: Neurocognitive Tests
Description: Baseline only: WRAT Reading Test, WMS-IV Logical Memory Subtest, Hopkins Verbal Learning Test (HVLT), Oral Trailmaking - Part A and B, NAB Digit Span, Category Fluency Test, Oral Symbol Digit Modalities Test, Brief Test of Attention, FAS - Controlled Oral Word Association Test (COWAT), Verbal Naming, Enformia Cogsuite Battery