AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05514704 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Therapy via mobile application
Description: The intervention will include the different levels of the following exercises that are given to the patient considering their functional level:~1. Straight leg raise (Level 1-2-3)~2. Quadriceps strengthening (Level 1-2-3)~3. Hip abductor/adductor strengthening (Level 1-2-3)~4. Hamstring stretch~5. Gastrocnemius stretch
Study NCT04103489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eculizumab
Description: Participants will receive eculizumab at diagnosis of HELLP syndrome. Participants will receive a maximum of 4 doses.
Study NCT05696275 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: exercise
Description: 20-30 minutes of walking and elastic band exercise per day
Study NCT05589779 — intervention group
Intervention type: OTHER
Intervention: Asthma and cardiovascular disease
Description: To know the clinical and inflammatory characteristics of patients with asthma and associated cardiovascular disease, as well as their relationship with eosinophil subtypes, biomarkers of chronic inflammation and bronchial remodeling.
Study NCT05804643 — intervention group
Intervention type: PROCEDURE
Intervention: Diffusion magnetic resonance imaging
Description: Free water elimination diffusion MRI and diffusion kurtosis MRI techniques
Study NCT05057260 — intervention group
Intervention type: OTHER
Intervention: No drug invervention
Description: No clinical trial
Study NCT04668651 — intervention group
Intervention type: OTHER
Intervention: antral ultrasound
Description: Preoperative evaluation of gastric contents by antral ultrasound
Study NCT05662475 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: GCF (gingival crevicular fluid) collection
Description: Prior to GCF (gingival crevicular fluid) sampling, supragingival plaque was removed by sterile curets and, after air drying, the surfaces were isolated by cotton rolls. Gingival fluid collection strips were placed in sulcus for 30s. Care was taken not to avoid mechanical trauma and strips contaminated with blood or saliva were discarded. The absorbed GCF volume was estimated by a calibrated instrument. Then, the strips were sealed into sterile tubes before freezing at -80 °C. The readings were converted to an actual volume (μl) by reference to the standard curve.
Study NCT05662475 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Non-surgical periodontal treatment completed in 24 hours
Description: After clinical periodontal parameters were recorded and GCF samples were obtained, non-surgical periodontal treatment was started under local anesthesia. All periodontal treatments were performed by a single investigator. Local infiltrative anesthesia was applied to the buccal and palatal/lingual areas of the maxilla and mandible of the patients. After anesthesia was achieved, scaler and ultrasonic tips of various thicknesses were used together to remove supragingival and subgingival hard attachments. Root surface smoothing was performed with region-specific periodontal curettes. The roughness of the surfaces was controlled using a periodontal probe. Polishing was performed. Oral hygiene education was given to each patient after treatment. Modified Bass technique was explained as a brushing technique. Interdental cleaning is explained. The patient was told not to use any chemical agent for plaque removal.
Study NCT05662475 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: HbA1c level determination in blood serum
Description: Blood samples were taken from the patients and HbA1c concentration was measured in serum.
Study NCT05968898 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optellum Virtual Nodule Clinic
Description: The Optellum Virtual Nodule Clinic is an FDA-approved (Class II) device for risk stratification of pulmonary nodules. It uses a convolutional neural network to evaluate CT imaging data to provide an estimate of malignancy risk for indeterminate pulmonary nodules.
Study NCT06134050 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Procedure: HTO using PSI aiming at 55% correction
Description: HTO using PSI designed to achieve correction to 55% tibial width.
Study NCT06134050 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Procedure: HTO using PSI aiming at 62% correction
Description: HTO using PSI designed to achieve correction to 62% tibial width.
Study NCT04656314 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Functional MRI scan
Description: Functional MRI scan: Phase contrast, BOLD, Arterial Spin Labeling, Diffusion weighted MRI, T1 mapping, T1rho mapping
Study NCT05335018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glofitamab, Poseltinib, Lenalidomide
Description: Glofitamab: Increase from 2.5mg for 8days in 1 cycle to 10mg for 15days. 2cycles 1day 30mg, 30 mg on the 1st day of every week thereafter. Poseltinib: 40mg/day bid orally, administered daily from the 1st to the 21st of every week.~Lenalidomide: 20mg/day bid orally, administered daily from the 1st to the 14st of every week.
Study NCT05351047 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD2373 subcutaneous injection
Description: Randomized subjects will receive multiple ascending dose of AZD2373 by SC injection (dose 1, dose 2, dose 3, dose 4, dose 5).
Study NCT05351047 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Randomized subjects will receive a multiple ascending dose of placebo (saline solution) by SC injection.
Study NCT06072989 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: B4T2-001 autologous CAR-T
Description: Each subject will receive multiple intravenous infusions of B4T2-001 autologous CAR-T without preparative chemotherapy (lymphodepletion)
Study NCT05479279 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neck Stabilization Training Program
Description: 3 times a week stretching exercises approximately 10 mins dumb bell exercises - 2 sets of 15 reps with weights varying from 1 to 2 kg cranio-cervical isometrics for 10 sec with 15 sec breaks between holds with 10-15 reps Tens 5-10 mins Hotpack 5-10 mins neck stretches home plan - 5 reps/set, 3 sets/ day
Study NCT05479279 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Tens 5-10 mins Hotpack 5-10 mins neck stretches home plan - 5 reps/set, 3 sets/ day
Study NCT05139849 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vasopressin; Methylprednisolone; Hydrocortisone
Description: Vasopressin, the vasoconstrictive hypophysal hormone, alone has not shown increased survival when compared to adrenaline. However, animal data have shown increased diastolic pressure, cerebral perfusion pressure and cerebral oxygenation in cardiac arrest treatment with vasopressin, and have when compared to adrenaline been associated with better cerebral blood flow.~Corticosteroids are currently used in septic shock treatment as a means to reduce time to shock reversal and thereby potentially improving mortality. Steroids have therefore also been suggested for cardiac arrest treatment. The potential role in resuscitation includes the catecholaminerg potentiation, vasoconstriction and protection from reperfusion injury.
Study NCT05139849 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sodium chloride
Description: Sodium chloride 9 mg/ml
Study NCT04812067 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TTHX1114
Description: engineered FGF-1
Study NCT06301672 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric Tube Feeding
Description: Nasogastric Tube Feeding were used for feeding to provide nutritional support. Each feeding was administered by a nurse using the infant's mother's breast milk through the tube. The amount of each feeding varied from 20 to 100 ml depending on the age of the infant, with feedings given every 2 to 3 hours, approximately 10 times per day. The duration of each feeding procedure ranged from 10 to 20 minutes. The total daily intake ranged from 200 to 1000 ml. Each tube was kept indwelling for 5 to 7 days. When the tube needed to be replaced, it was removed after the last feeding of a day and a new tube was to be inserted through the other nostril on the following morning to continue the nutritional support.
Study NCT06301672 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oral-esophageal Tube Feeding
Description: The specific procedure was as follows: the infant was placed in a semi-recumbent or sitting position with the head fixed. Before each feeding, the infant's oral and nasal secretions were to be cleared. An intermittent oro-esophageal tube was appropriately lubricated with water on the head part. The professional medical staff held the tube and slowly inserted it through one side of the mouth into the upper part of the esophagus. The depth of insertion depended on the patient's age and height. After each feeding, the tube was immediately removed, and the patient was held upright for at least 30 minutes in case of reflux.
Study NCT06301672 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: comprehensive rehabilitation therapy
Description: Both groups were given comprehensive rehabilitation therapy. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.
Study NCT06301672 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: comprehensive rehabilitation therapy
Description: Both groups were given comprehensive rehabilitation therapy. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.
Study NCT04760951 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: TOTUM-070
Description: 5-g dose of TOTUM-070 diet supplement, a mix of 5 plant extracts. Eight capsules per day to consume orally in two intakes
Study NCT04760951 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo. Eight capsules per day to consume orally in two intakes
Study NCT06469099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: excercises
Description: exercises for strength and balance
Study NCT06178250 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 3D sonography
Description: Fetal liver, placenta, and ductus venosus were defined in 3 orthogonal multi-plane images in the voluson 4D view vocal program.
Study NCT05611788 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Structure Learning Training
Description: Participants will undergo 12 sessions of structure learning training lasting about 1 hour each along with 2 testing sessions interspersed within the 12 training sessions. Each session will be conducted in a remote-guided manner with an approximate 1-day gap in between sessions. The entire training will last around two weeks
Study NCT05017220 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nature-based sensory stimuli
Description: A program based on stimulation using nature-based sensory stimuli will be implemented
Study NCT05017220 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control group intervention
Description: An activity based on a placebo intervention will be implemented
Study NCT06490393 — intervention group
Intervention type: OTHER
Intervention: Questionnaires
Description: EORTC QLQ-C30 (General Health), EORTC QLQ-SH22(sexual Health), Financial questionnaire as routinely used by the Social Department
Study NCT05968599 — intervention group
Intervention type: DRUG
Intervention: Enzalutamide
Description: As provided in real-world setting
Study NCT05968599 — intervention group
Intervention type: DRUG
Intervention: Abiraterone acetate
Description: As provided in real-world setting
Study NCT05663658 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous morphine patient control device
Description: 24-hour morphine consumption will be recorded
Study NCT05663658 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: External oblique intercostal plane block
Description: External oblique intercostal plane block will be administered before the surgery.
Study NCT06216184 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Vortexing
Description: use combined of vortexing and Maki techniques
Study NCT05234554 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reproxalap Ophthalmic Solution (0.25%)
Description: Reproxalap Ophthalmic Solution (0.25%) dosed twice.
Study NCT05234554 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Ophthalmic Solution
Description: Vehicle Ophthalmic Solution dosed twice.
Study NCT05454436 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: sinus tract healing in single or multi visit with single cone technique with bioceramic sealer
Description: Investigators will see the healing rate between single visit and multi visit with single cone technique with bioceramic sealer .
Study NCT06373471 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Comprehensive geriatric assessment (CGA) and treatment
Description: CGA and treatment is as an outpatient evaluation by a geriatric medical specialist and nurse. Specific CGA components in this study include:~* Assessment of comorbidity and treatments~* Review of medications including potential adjustment~* Assessment of current symptoms and health related issues including geriatric syndromes such as depression, dementia, delirium, nutritional problems, falls and fatigue~* Objective examination including blood tests and electrocardiogram~* Assessment of activities of daily living (ADL) and instrumental ADL through standardized questionnaires~* Assessment of domestic conditions, including need for assistance~* Assessment of physical function Based on findings, the geriatrician will initiate relevant interventions and follow-up as required
Study NCT05997433 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 7days bismuth quadruple
Description: Amoxicillin 1000mg bid+ Tetracycline 500mg qid+ Bismuth + Tegoprazan 50mg bid\*7days
Study NCT05997433 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 14 days bismuth quadruple
Description: Amoxicillin 1000mg bid+ Tetracycline 500mg qid+ Bismuth + Tegoprazan 50mg bid\*14days
Study NCT05973097 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: total glucosides of paeony treatment
Description: Total glucosides of paeony capsules were given 0.6 g once, 3 times a day.
Study NCT05973097 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: photodynamic therapy treatment
Description: Cover the lesion with photosensitizer and fix it. Remove the photosensitizer and treat with laser diode.
Study NCT05973097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: glucosides of paeony and photodynamic therapy combined treatment
Description: Glucosides of paeony and photodynamic therapy are combined for the treatment
Study NCT06306079 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lateral Wedge insole
Description: Insoles with lateral wedges are placed in patients' shoes to control biomechanical knee loading on the medial side of the knee. Insoles with lateral wedges are designed to be thinner on the inside (medially of the foot) and thicker on the outside (laterally of the foot) to relieve knee biomechanical loading parameters.
Study NCT03870516 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mitral valve replacement
Description: Replacing the diseased mitral valve in cases with severe mitral regurgitation with a prosthetic valve.
Study NCT03870516 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Mitral valve replacement
Description: Replacing the diseased mitral valve in cases with severe mitral regurgitation with a prosthetic valve.
Study NCT03870516 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Speckle tracking echocardiography
Description: We will perform Speckle tracking echocardiography in order to identify patients with early subclinical left ventricular or left atrial dysfunction and refer them to surgery, Then after surgery, speckle tracking echocardiography will be performed for all patients to assess improvement of left atrial (conduit, reservoir and booster contractile functions) and left ventricular (global longitudinal strain) function
Study NCT03870516 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Speckle tracking echocardiography
Description: We will perform Speckle tracking echocardiography in order to identify patients with early subclinical left ventricular or left atrial dysfunction and refer them to surgery, Then after surgery, speckle tracking echocardiography will be performed for all patients to assess improvement of left atrial (conduit, reservoir and booster contractile functions) and left ventricular (global longitudinal strain) function
Study NCT05443893 — intervention group
Intervention type: DEVICE
Intervention: Application Research of key points detection technology
Description: Artificial intelligence human key point detection model mainly has traditional algorithm, top-down algorithm and bottom-up algorithm three methods, three methods have advantages. This project will comprehensively use the above three methods to conduct algorithm and parameter debugging in the public data set and test in the private data set, so as to obtain the most suitable human key point recognition method for gait analysis
Study NCT06013657 — intervention group
Intervention type: PROCEDURE
Intervention: Liver Resection
Description: Resection of a part of the liver afflicted by hepatocellular carcinoma
Study NCT05281796 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: GCF obtaining
Description: GCF sample collection by Enzyme-Linked Immunosorbent Assay (ELISA)
Study NCT05281796 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: saliva obtaining
Description: Saliva sample collection by Enzyme-Linked Immunosorbent Assay (ELISA)
Study NCT06387849 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aromatherapy
Description: women enrolled in the experimental group received aromatherapy with lavender essential oil (EO) through dry inhalation (inhalation via a cotton support soaked in a few drops of EO)
Study NCT06387849 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: women enrolled in the placebo group received ihaled a cotton support soaked in a few drops of distilled water
Study NCT05563922 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Total Neoadjuvant Chemoradiotherapy
Description: Radiotherapy：45Gy/25F+Boost 50Gy/25F. A total of 45 Gy, 25 fractions of 1.8 Gy, 5 fractions a week~CapOx:~Capecitabine 1000mg / m² po bid (1-14 days, 21 days a cycle) Oxaliplatin 130mg / m2 igtt(Day 1, 21 days a cycle) TEM or endoscopic local resection
Study NCT05546294 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aerobic and home exercise
Description: A total of 20 sessions of aerobic exercises using bicycle ergometer, five times a week and once a day for four weeks, were applied to the patients.Maximum heart rate was calculated for each subject (220 - age) and a heart rate monitor will be used to follow subjects' heart rate during aerobic exercise.~Then the patients were showed a daily home exercise program to apply once a day at their home.~As a daily home exercise program:ROM exercises and strengthening exercises for major muscle groups (such as abdominal muscles, erector spinae, hamstring, quadriceps, hip flexors, strengthening exercises for all extremities) were showed.~At the beginning of the treatment and at the end of the treatment (4th week), serum BDNF and irisin levels will be tested using the ELISA kit, with blood samples taken from the RA patients in the early morning.
Study NCT05546294 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home exercise
Description: The patients were showed only a daily home exercise program to apply once a day at their home.~As a daily home exercise program:ROM exercises and strengthening exercises for major muscle groups (such as abdominal muscles, erector spinae, hamstring, quadriceps, hip flexors, strengthening exercises for all extremities) were showed.~At the beginning of the treatment and at the end of the treatment (4th week), serum BDNF and irisin levels will be tested using the ELISA kit, with blood samples taken from the RA patients in the early morning.
Study NCT05546294 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Healthy control group
Description: Serum BDNF and irisin levels will be tested using the ELISA kit, with blood samples taken only once from healthy control group in the early morning. It will be checked whether there is a difference between the basal serum BDNF and irisin levels of rheumatoid arthritis patients and healthy control group.
Study NCT05009927 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imatinib tablets
Description: Imatinib interruption