AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04949009 — intervention group
Intervention type: DRUG
Intervention: Avatrombopag
Description: Avatrombopag is an orally bioavailable, small molecule thrombopoietin receptor agonist that has been developed by Dova Pharmaceuticals for the treatment of thrombocytopenic disorders.
Study NCT06477783 — intervention group
Intervention type: DRUG
Intervention: Teclistamab
Description: Intervention is part of standard clinical care, as Tecvayli/Teclistamab is reimbursed for this group of patients.
Study NCT05870345 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Butterfly IQ
Description: Butterfly IQ is a pocket sized ultrasound device. Each participant will undergo a ultrasound exam of both elbows using a pocket sized ultrasound device.
Study NCT05836285 — intervention group
Intervention type: OTHER
Intervention: ARRC
Description: Eligible for ARRC and managed in ARRC unit
Study NCT05836285 — intervention group
Intervention type: OTHER
Intervention: Usual Care
Description: Eligible for ARRC but managed elsewhere as no ARRC bed available
Study NCT06279611 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY007
Description: FC and LY007 infusion
Study NCT06157034 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Inert Material
Study NCT06157034 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Zingier officinale powder
Description: The raw form of Zingiber officinale will be grounded in powder by manual grinding and will be encapsulated.
Study NCT06157034 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Carum carvi, L powder
Description: The raw form of Carum carvi, L will be grounded in powder by manual grinding and will be encapsulated.
Study NCT06157034 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mentha spicata oil
Description: Mentha spicata L will be extracted in the form of oil and will be encapsulated.
Study NCT05670405 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Trauma PORTAL
Description: Participants will have 9 weeks to complete the 8 modules which each take on average 45 minutes to complete. Each module consists of psychoeducational handouts, videos, interactive exercises, and discussion topics that has been adapted from the R\&R curriculum. The participants will also receive a pdf of the handouts from the modules, which can be used to take notes or refer back to in the future.~There will be an optional 60-minute weekly virtual group session for participants to engage with other participants in their group and for group facilitator providers to discuss the materials covered and answer any questions. Participants will join a Zoom video group visit to access the group. Each weekly group will be facilitated by 2 clinicians specializing in trauma-focused therapy within the WCH TTP who have extensive experience with in-person and virtual synchronous R\&R.
Study NCT05348811 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC combined with donafenib and sintilimab
Description: HAIC- GEMOX regimen, gemcitabine 1000 mg/m2, oxaliplatin 85mg/m2 (if the maximum tumor diameter > 10cm, the dose is 130mg/m2), the first day of each cycle (D1), Q3W. The maximum of 6 times.~Sintilimab will be given on the first day of each cycle (D1). 200 mg i.v. every 3 weeks until documented disease progression, development of unacceptable toxicity, participant request, or withdrawal of consent.The longest treatment time is 24 months.~Donafenib was taken orally at 0.2 bid on an empty stomach (1 hour before or > 2 hours after meal) in the morning and evening of each administration day, with an interval of about 12 hours. Donafenib treatment is initiated within 1 to 3 days of each HAIC treatment until toxicity is intolerable, the investigator determines disease progression, death, informed consent is withdrawn, new antitumor therapy is initiated, or treatment is discontinued for any other reason specified in the protocol.
Study NCT05317130 — intervention group
Intervention type: OTHER
Intervention: Athlete health monitoring
Description: Observational study
Study NCT05653583 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Wrist Device
Description: peripheral nerve stimulation via wrist-worn device
Study NCT05653583 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ear Device
Description: peripheral nerve stimulation via ear-worn device
Study NCT05653583 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Device
Description: Wrist-worn device that does not actually deliver stimulation
Study NCT06070987 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BoNT-A injections
Description: Botox brand BoNT-A Purified Neurotoxin Complex, (Allergan Pharmaceuticals, Irvine, CA) will be prepared by diluting lyophilized toxin with 0.9% saline to a concentration of 33-100 U/ml. depending on the size of the target muscle. Location of the targeted muscle will be confirmed by using echo guide. The total dose range is 100 units. The dose range of each target muscle is as below:100 units in rectus femoris.
Study NCT05830188 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coping and Resilience Intervention for Adolescents
Description: It is a school-based resilience enhancement program to help adolescents build skills of positive coping and social support to minimize negative coping and distress by sharing, identifying, and discussing their feelings, thoughts, and actions regarding problems and stressful events.
Study NCT05830188 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Printing materials of Coping and Resilience Intervention for Adolescents
Description: Printing materials for the CERIA sessions will be given to school counselors who provide school counseling programs in the control group.
Study NCT06070987 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BoNT-A injection and robot therapy
Description: Wearable overground exoskeleton lower extremity robot system will be used in this study. The robot lower extremity system consisted with bilateral motors for assisting left and right knees, a pelvis belt and chariot system for suspending the device, and thigh and shank cuffs for attaching the exoskeleton links to the user. Patients will wear receive exoskeleton lower extremity robot after BoNT-A injected in the affected rectus femoris, then start to do the functional ambulation training to do 1) walking over ground 2) walking with turning, 3) get in and out of chair, 4) crouching and rising, and 5) going up and down stairs.
Study NCT06070987 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: None BoNT-A injection and robot therapy
Description: Wearable overground exoskeleton lower extremity robot system will be used in this study. The robot lower extremity system consisted with bilateral motors for assisting left and right knees, a pelvis belt and chariot system for suspending the device, and thigh and shank cuffs for attaching the exoskeleton links to the user. Patients will wear receive exoskeleton lower extremity robot (do not inject BoNT-A in the affected rectus femoris), then start to do the functional ambulation training to do 1) walking over ground 2) walking with turning, 3) get in and out of chair, 4) crouching and rising, and 5) going up and down stairs.
Study NCT04648124 — intervention group
Intervention type: DEVICE
Intervention: IRMf-r (séquence resting state)
Description: Functional MRI of functional brain networks
Study NCT06368570 — intervention group
Intervention type: OTHER
Intervention: Interview
Description: Patients will be interviewed by the research team to learn about their experience of Cesarean delivery with neuraxial anesthetic
Study NCT05715697 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham procedure and maintenance of heart failure medications
Description: Sham intervention, maintenance of heart failure medications
Study NCT05715697 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Renal denervation and maintenance of heart failure medications
Description: Renal denervation and maintenance of heart failure medications
Study NCT05784857 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Touch Methods
Description: The Yakson touch method continue for 15 minutes with steady touch (5 minutes), compassionate caressing (5 minutes), and repetition of steady touch (5 minutes). In this method, the palms of the practitioner and all fingers keep in close contact so that the babies don't feel pressure.~Gentle human touch refers to steady contact of the skin without caressing or massaging. While the practitioner place one hand on the crown of the preterm infant on the eyebrow line with the fingertip touch for 15 minutes, the other hand was place on the lower abdomen covering the waist and hip of the infants.
Study NCT05412615 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Meniscus Allograft Transplantation with Proximal Row Carpectomy
Description: Supplementing the wrist reconstruction with a meniscal allograft to improve wrist function and pain scores.
Study NCT05412615 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Proximal Row Carpectomy
Description: Standard proximal row carpectomy with no tissue or synthetic adjuncts
Study NCT06563843 — intervention group
Intervention type: PROCEDURE
Intervention: Robotic-assisted TKA
Description: Robotic-assisted Total Knee Arthroplasty or total knee replacement is a surgical procedure using a robot to resurface a knee joint damaged with arthritis, and where the knee joint of the patient is replaced with a prosthesis.
Study NCT06563843 — intervention group
Intervention type: PROCEDURE
Intervention: Conventional TKA
Description: Conventional Total Knee Arthroplasty or total knee replacement is a surgical procedure to manually resurface a knee joint damaged with arthritis, and where the knee joint of the patient is replaced with a prosthesis.
Study NCT05390788 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Application Of Neuromuscular Bands; Kinesio Taping
Description: Kinesio tape is a specialized elastic and adherent adhesive tape that mimics the elasticity of skeletal muscle, in that it can be extended up to 140% of its original length, before application to the skin, without allowing restrictions in the range of motion. of structures. Subsequently, it provides a tensile (shear) force on the skin, consisting of a fabric with special characteristics, such as air permeability and water resistance, and can be used for repeated days. Kinesio will be applied from a point 10 cm below the anterior superior iliac spine and divided in a Y shape above the patella, ending at the tibial tuberosity; from the upper third of the medial thigh to the medial border of the patella; from the greater trochanter of the femur, ending at the lateral margin of the patella.
Study NCT05740514 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Exercise training.
Study NCT05643157 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Adaptive Optics - Optical Coherence Tomography (AO-OCT) retinal imaging
Description: AO-OCT used in this study is an investigational OCT imaging system. . In this instrument, ocular aberration sensing and correction is achieved with a Shack-Hartmann wavefront sensor (SHWS) and deformable mirror, respectively. A pupil camera and fixation target are used to position the participant's head and eye for scanning a particular retinal region within 15 degrees of the fovea. Data collected generally includes AO-OCT volume videos and SHWS measurements of ocular aberrations.
Study NCT05257135 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biological collection
Description: - Blood samples collected at different times: at inclusion and during treatment ( every 6 month)
Study NCT05740514 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: De-training
Description: Exercise de-training via unilateral knee immobilization.
Study NCT05453214 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludrocortisone Acetate 0.1 MG
Description: Fludrocortisone acetate 0.1 mg tablet / 12 hours; dose to be titrated according to response.
Study NCT05126745 — intervention group
Intervention type: DEVICE
Intervention: color flow Doppler ultrasonography
Description: Doppler ultrasonography
Study NCT06418126 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood sampling before radiotherapy
Description: A blood sample (20 ml) will be taken prior to radiotherapy
Study NCT06418126 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood sampling after the fourth radiotherapy session
Description: A blood sample (20 ml) will be taken immediately after the 4th radiotherapy session.
Study NCT06418126 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of acute toxicity (radiodermatitis)
Description: for the entire duration of radiotherapy
Study NCT06418126 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of late toxicity
Description: every year for 5 years
Study NCT06418126 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of disease status
Description: throughout the study
Study NCT06418126 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy - Breast +/- lymph node areas
Description: 40.05 Gy in 15 fractions of 2.67 Gy, one fraction per week, 5 days per week Or 50 Gy in 25 fractions of 2 Gy, one fraction per week, 5 days per week
Study NCT05407701 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cranberry Juice
Description: 100% cranberry juice
Study NCT05407701 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo juice
Study NCT06418126 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy - Boost operating bed
Description: 10 Gy in 4 fractions of 2.5 Gy, one fraction per week, 5 days per week Or 16 Gy in 8 fractions of 2 Gy, one fraction per week, 5 days per week
Study NCT05186909 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 Recombinant Humanized Monoclonal Antibody Injection
Study NCT05186909 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05701488 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Intravenous infusion
Study NCT05701488 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Intravenous infusion
Study NCT04244682 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Repetitive transcranial magnetic stimulation (rTMS)
Description: In the rTMS procedure a small plastic coil will be placed next to the participant's head. The position of the coil will be guided by neuro-navigational software utilizing the individual's MRI scan. The coil will be placed over the relevant brain region using the Brainsight TMS-MRI co-registration system for visualizing the coil position with respect to the participant's individual MRI scan. The coil will then generate a series of repetitive magnetic pulses, and stimulation will occur, disrupting typical function of the targeted brain region.
Study NCT05701488 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SIRT
Description: SIR (Selective Internal Radiation) Sphere resin microspheres, radioactive particles delivered via injection into an artery.
Study NCT06240715 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Umbilical cord milking
Description: At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 1--15 seconds.
Study NCT05895734 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NDS-Powerball®,
Description: Rehabilitation using the Powerball system
Study NCT05895734 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Rehabilitation by conventional treatment
Study NCT06454851 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prosocial VR intervention
Description: A four-week gamified prosocial VR intervention program based on literature review and relevance to the local contexts will be developed for the proposed project. The intervention will be expanded to include four weekly sessions, each lasting between 15 to 20 minutes. Each session will depict a different daily life scenario-campus, lecture hall, canteen, and library, respectively. During each session, participants will engage in a series of tasks that incorporate elements of prosocial behavior or helping actions within the scene. These tasks are designed to be more comprehensive and interactive, ensuring that participants are fully immersed in the experience for the entire duration of the session.
Study NCT06454851 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: No intervention
Description: The waitlist control group will not receive the intervention during the study.
Study NCT05551338 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious games
Description: The training protocol will entail using a tablet-based program that includes 6 serious games. Patients will be asked to use the program twice a week for 3 months. The serious games that will be used in this study were developed to challenge short-term memory and selective attention in six different games. Each of the six games comprise 20 different stages of varying difficulty, where stage 1 is the easiest and stage 20 is the most difficult.
Study NCT05204511 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: endurance training
Description: endurance training of low to moderate intensity on a bicycle ergometer, crosstrainer or treadmill performed for 30-60 minutes per session
Study NCT05204511 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: concurrent training
Description: combination of endurance training of low to moderate intensity on a bicycle ergometer, crosstrainer or treadmill performed for 20-40 minutes per session and resistance training of moderate intensity performing 2-3 sets of leg press, leg curls, chest press and seated horizontal rows
Study NCT05442242 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Unicompartmental knee arthroplasty
Description: Medial Unicompartmental knee arthroplasty
Study NCT05442242 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High tibial osteotomy
Description: Medial open wedge high tibial osteotomy
Study NCT06191120 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F]-ALF-FAPI-74 PET/CT scan
Description: Participants will receive up to three \[18F\]-ALF-FAPI-74 PET/CT scans. \[18F\]-ALF-FAPI-74 is a PET tracer with high binding specificity and selectivity to FAP-expressing cells.
Study NCT06405698 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical closure of myelomeningocele defects by perforator flaps
Description: closure of myelomeningocele defect by perforator island flap after complete incision of the flap all around based on perforator vessel .
Study NCT06271824 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-Compassion Based Resilient Caregiving Course
Description: The Resilience Habits for Caregivers Course is a live, online, weekly 6 session program lasting 1.5 hours per session. The structure contains didactics, group discussions, guided exercises, and practices facilitated by a certified self-compassion instructor. Topics covered include: (1) noticing and accepting emotions (including conflicting emotions); (2) cultivating curiosity and self-compassion; (3) relating skillfully to difficult thoughts; (4) savoring and gratitude practices.
Study NCT05261880 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neural mobilization
Description: Neural mobilization and bone are two common physical therapy interventions used for Carpal Tunnel Syndrome. Neural mobilization reinstates the plasticity of the nervous system and restoring the capacity of stretching.
Study NCT05261880 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scaphoid , hamate mobilization
Description: Bone mobilization in Carpal Tunnel Syndrome involves gliding at scaphoid and hamate.
Study NCT05912309 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time Restricted Eating (TRE)
Description: Participants will be required to reduce their eating time window to ≤ 8 hours/day. Women can choose when to begin eating, but the last meal should be completed before or at 20:00 hours (concentrating the eating window towards the active phase confers higher cardiometabolic health benefits). Our preliminary results suggest that this eating window is feasible and safe. Participants will receive dietary advice regarding the daily amount of high quality protein and meal-specific protein quantities. All the participants will attend a lifestyle education program based on Mediterranean diet and WHO physical activity recommendations every two weeks.
Study NCT05912309 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Sport sciences specialists will design, supervise and monitor the concurrent exercise intervention following the 2020 WHO recommendations. The program will be tailored to the participant's ability and health, and will be focused on a gradual increase to levels that are safe. Resistance training: 3 times/week designed to manage, attenuate and even prevent the loss of skeletal muscle tissue and function. The exercise sessions will be scheduled within or immediately after their eating window in order to maximize muscular muscle protein synthesis. Morning and afternoon training schedules will be offered to participants.
Study NCT05912309 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Sport sciences specialists will design, supervise and monitor the concurrent exercise intervention following the 2020 WHO recommendations. The program will be tailored to the participant's ability and health, and will be focused on a gradual increase to levels that are safe. Resistance training: 3 times/week designed to manage, attenuate and even prevent the loss of skeletal muscle tissue and function. The exercise sessions will be scheduled within or immediately after their eating window in order to maximize muscular muscle protein synthesis. Morning and afternoon training schedules will be offered to participants.