AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04731311 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Usability evaluation of BrightGo computerized device for cognitive therapy of individuals with early Alzheimer's Disease
Description: 4 participants with undergo 4 usability evaluations each, inter-spaced by days when researchers will address design changes. 2 participants will be elderly healthy and 2 will have the early Alzheimer's disease. Each session will last up to 1 hour, during which participants will interact with tasks in the form of games. Games will be gradated in level of difficulty, increasing from session to session. They will be played with one game controller or with two controllers while participants wear an all-in-one head mounted display. The degree of cognitive engagement during tasks will be measured with custom biosensors and used in adjusting level of difficulty. Each participant will fill subjective evaluation form and a USE form assessing ease of use, usefulness, and perceived technology issues. Scores will be analyzed and data published, in conjunction with game performance data.
Study NCT04719104 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Bilirubin Meter - 'Bilimeter'
Description: Taking a transcutaneous (TcB) measurement will involve using a 'biliflash'. This is a non-invasive measurement that involves flashing a light against the helix of the infant's ear and can be done at the cotside. This process takes approximately 1-2 minutes and does not cause the baby discomfort. The meter gives an immediate bilirubin level.
Study NCT05076045 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Personal sound amplification products
Description: Participants will be tested with bilateral personal sound amplification products.
Study NCT05910047 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Supplement
Description: Dietary supplement containing molecular hydrogen and pyrroloquinoline quinone
Study NCT05910047 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inert substance
Study NCT06368401 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Versa Implant
Description: The Versa Vascular Implant and Delivery System consists of a percutaneously delivered, permanent right-atrial implant and the delivery catheter that is used to first position the implant over the native valve orifice and to then place the implant.
Study NCT05859178 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise group
Description: Along with nerve transfer surgery, individuals in the exercise group will undergo handgrip exercise for 30 minutes a day, 5 days a week for a total of 12 weeks.
Study NCT06044935 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Diet
Description: Consisting of 15% protein, 35% fat, and 50% carbohydrate, matching the macronutrient composition of a typical American diet
Study NCT06044935 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic Diet
Description: Consisting of a macronutrient composition of 15% protein, 80% fat, and 5% carbohydrate
Study NCT06044935 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects without MODY2 will take either placebo or NR (1 g BID, 2 g per day total) supplements for 7 days during this Run-in phase
Study NCT06044935 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nicotinamide Riboside
Description: Subjects without MODY2 will take either placebo or NR (1 g BID, 2 g per day total) supplements for 7 days during this Run-in phase
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: tooth extraction
Description: The study tooth will be removed
Study NCT02579187 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: CBCT scan
Description: a CBCT scan limited to the dental arch that includes the study side will be obtained
Study NCT02579187 — intervention group
Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: CBCT scan
Description: a CBCT scan limited to the dental arch that includes the study side will be obtained
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anesthesia
Description: all subjects will receive local infiltrative anesthesia, prior to extraction of the tooth
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Anesthesia
Description: all subjects will receive local infiltrative anesthesia, prior to extraction of the tooth
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: clinical measurements
Description: After tooth extraction, clinical measurements of the site will be obtained and recorded (keratinized mucosa width, horizontal ridge width, facial and lingual bone thickness
Study NCT04666857 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: early motor intervention
Description: infants with CHD after open heart surgery will receive early intervention
Study NCT05640154 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: educational program
Description: The nursing educational program will be implemented in small groups from (5-7) in outpatient clinics. It includes nutrition, exercise, control hypertension , engage in weight control measures, smoking cessation, stress management, breathing exercise, appropriate treatment of diseases, control of diabetes, control of cholesterol in blood and routine follow up).
Study NCT05210257 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Conventional physiotherapy
Description: Group 1 was given conventinal physiotherapy Physiotherapy agents; 5 min ultrasound 1.5 watts/cm2 20 min conventional TENS 20 min heat agent application (hot pack) Exercise program; Stretching and relaxation exercises, Neck strengthening exercises that include concentric and isometric contractions Posture exercises 3 sets per day, 1 in the hospital with 10 repetitions
Study NCT05210257 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neuroscience education
Description: Conventional physiotherapy program and The neuroscience education trainings will be conducted in the form of face-to-face interviews and 45-50 minute one-to-one sessions.~In sessions ; neurons and nerve conduction in the session, the formation process of pain, peripheral neuropathic pain, pain spread during the session, neuroplasticity, peripheral and central sensitization, hyperalgesia and allodynia, acute-chronic pain, The effects of stress, fear, anxiety, false thoughts and beliefs about pain and other psychosocial factors on the pain process and determining possible psychosocial factors in the patient during the session, Strategies for controlling the pain process and coping with psychosocial factors in the session will be completed by explaining the effect mechanisms of exercise on pain.
Study NCT05925920 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ENT-03
Description: single dose of active drug
Study NCT05925920 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: single dose of placebo comparator
Study NCT05176106 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CHW Incentives Intervention
Description: The intervention comprises of an incentives package provided to VHTs who are active in the intervention-randomized parishes. It will comprise of items that will motivate them and support their work as VHTs in the community.
Study NCT05167656 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intraoral manual therapy
Description: Six intraoral manual therapy sessions based on ischemic compression and pain pressure release of the temporomandibular region muscles, applied bilateral.
Study NCT05167656 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Extraoral manual therapy
Description: Six extraoral manual therapy sessions based on ischemic compression, pain pressure release and pressure sliding of the temporomandibular region muscles, applied bilateral.
Study NCT05167656 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise and counselling
Description: Information about etiology, contributing and related factors, natural history and prognostic of the pathology of temporomandibular disorders.~Counselling based on: diet, habits like tabacism, stress and anxiety control, physical activity and awareness of dental clenching.~Exercise daily program based on active and passive mobility of the temporomandibular joint, stretching exercises and self massage.
Study NCT05237583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation
Description: All participants will be offered a multimodal prehabilitation program. This program will include an individualized and supervised aerobic and resistance exercise training program, nutritional optimization, and psychological support. The program will last 6 months or until liver transplantation, whichever comes first.
Study NCT06325215 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hidrocolloid Bant
Description: In this group, after the columella and nasal area of preterm infants were cleaned and dried with sterile water, hydrocolloid dressings were applied to the areas in contact with the nasal cannula. NasalNem nasal ointment was applied twice a day to the nasal passages in contact with the cannula. If the hydrocolloid dressings melted or peeled off, they were removed, the area was cleaned, and then reapplied.
Study NCT05709847 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Coffee
Description: 24 ounces of coffee will be consumed daily
Study NCT05709847 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Coffee
Description: 24 ounces of coffee will be consumed daily
Study NCT05267912 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: We need a biopsy for PDO: PDOs are tridimensional multicellular structures expanded in vitro which retain the genotypic and phenotypic features of their tissue or tumor of origin. PDOs can be exposed to a panel of drugs (chemotherapy, hormonal therapy, targeted therapy) in order to study their sensitivity to each agent (or combination of agents) tested ('chemogram'). Recent studies showed that PDOs can accurately predict the response to treatment of solid tumors and could therefore inform clinical decision on the best therapeutic option for each patient.
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: clinical measurements
Description: After tooth extraction, clinical measurements of the site will be obtained and recorded (keratinized mucosa width, horizontal ridge width, facial and lingual bone thickness
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Biodegradable sponge (type I bovine collagen)
Description: control group subjects will receive a biodegradable sponge (type I bovine collagen) to stabilize the clot
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 10µg of pSil-miR200c
Description: subjects in the experimental group will receive a 10µg of pSil-miR200c plasmids in a biodegradable sponge (type I bovine collagen) to stabilize the clot
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cross mattress suture
Description: The site will be stabilized with a simplet external, cross mattress suture
Study NCT05167656 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise and counselling
Description: Information about etiology, contributing and related factors, natural history and prognostic of the pathology of temporomandibular disorders.~Counselling based on: diet, habits like tabacism, stress and anxiety control, physical activity and awareness of dental clenching.~Exercise daily program based on active and passive mobility of the temporomandibular joint, stretching exercises and self massage.
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: cross mattress suture
Description: The site will be stabilized with a simplet external, cross mattress suture
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 10µg of PMIS miR200a plasmids
Description: subjects in the experimental group will receive a 10µg of PMIS miR200a plasmids in a biodegradable sponge (type I bovine collagen) to stabilize the clot
Study NCT02579187 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5µg of pSil-miR200c and 5µg of PMIS miR200a
Description: subjects in the experimental group will receive a 5µg of pSil-miR200c and 5µg of PMIS miR200a plasmids in a biodegradable sponge (type I bovine collagen) to stabilize the clot
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Blood
Description: Subjects will have venipuncture performed to obtain a small blood sample (approx. 2 ml) to assess for miR-200c and PMIS-miR-200a expression and liver function (AST, ALT, bilirubin levels)
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Blood
Description: Subjects will have venipuncture performed to obtain a small blood sample (approx. 2 ml) to assess for miR-200c and PMIS-miR-200a expression and liver function (AST, ALT, bilirubin levels)
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Photos/videos
Description: subjects will have photos and/or videos of the extraction site and/or implant taken at each visit.
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Photos/videos
Description: subjects will have photos and/or videos of the extraction site and/or implant taken at each visit.
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wound fluid
Description: a small sample of wound fluid will be obtained from the extraction site in a minimally invasive manner using a paper point at 1, 2, 3 \& 4 weeks post extraction
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Wound fluid
Description: a small sample of wound fluid will be obtained from the extraction site in a minimally invasive manner using a paper point at 1, 2, 3 \& 4 weeks post extraction
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: saliva
Description: approximately 2 mls of saliva will be obtained in a minimally invasive manner at the time of extraction and at 14 weeks post extraction.
Study NCT05109819 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Esophagus sparring radiotherapy treatment
Description: A radiotherapy plan for metastatic spinal cord compression is conducted with specific constrains sparring the esophagus.
Study NCT05625854 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Blow a fan to the face combine aromatherapy
Description: Blow a fan with aromatherapy to the face
Study NCT05625854 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Blow a fan to the face
Description: Blow a fan to the face
Study NCT05625854 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Blow a fan to the feet
Description: Blow a fan to the feet
Study NCT06512948 — intervention group
Intervention type: PROCEDURE
Intervention: High tibial osteotomy
Description: Surgical treatment for patients with osteoarthritis and indications for high tibial osteotomy
Study NCT05797454 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wire-guided localization and marker clip localization
Description: Positioning guide wire and marker clip in the center of the lesion
Study NCT05797454 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wire-guided localization
Description: Positioning guide wire in the center of the lesion
Study NCT05388591 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Musicotherapy
Description: Music listening with the application Music Care (style of music chosen by the patient) during wound suturing
Study NCT05350566 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Olive leaf extract
Description: A capsule containing 250 mg of an olive leaf extract preparation will be swallowed with a glass of water before exercise.
Study NCT05350566 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: A capsule containing 336 mg of cellulose microcrystalline will be swallowed with a glass of water before exercise.
Study NCT05217992 — intervention group
Intervention type: OTHER
Intervention: Genetic assessment (hemophilia testing)
Description: Determination of carrier ship of hemophilia with molecular tests
Study NCT04652583 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Earstim - Active Stimulation
Description: Intramuscular stimulation
Study NCT04652583 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Earstim - Sham Stimulation
Description: Sham stimulation
Study NCT05073562 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Iron and folic acid (IFA) supplementation
Description: Weekly IFA supplementation for duration of the study.
Study NCT05073562 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted nutrition education
Description: Structured nutrition education package delivered at household level by trained Community Health Assistants (CHAs)
Study NCT05073562 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mebendazole Pill
Description: One-time deworming treatment with mebendazole.
Study NCT05073562 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard nutrition services
Description: Basic nutrition services currently provided at the health facility and at community level in Liberia
Study NCT05300542 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Topical Placebo Cream
Description: Application of test products before and after irradiation
Study NCT05300542 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Topical Cream with 0.5% Active
Description: Application of test products before and after irradiation
Study NCT05300542 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Topical Cream with 1% Active
Description: Application of test products before and after irradiation
Study NCT02579187 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: saliva
Description: approximately 2 mls of saliva will be obtained in a minimally invasive manner at the time of extraction and at 14 weeks post extraction.
Study NCT02579187 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: periapical xray
Description: periapical xrays will be obtained at screening, 16 weeks and at 12 month followup time point
Study NCT04972916 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Patient navigation-based tobacco harm reduction intervention
Description: At the first intervention interview, the patient navigators will educate participants about the benefits of quitting, introduce smoking cessation resources, motivate participants to link with treatment, help participants attend smoking cessation treatments, and assess barriers that prevented them from being able to consider smoking cessation. The cessation treatment resources will be discussed include PennState Health Smoking Cessation Clinic, Pennsylvania Quitline, or visiting their primary care provider (PCP) to discuss cessation, prescription medications, and/or nicotine replacement therapy. A follow-up call will be made 1 month later to further assist and motivate to use tobacco treatment services, and assess interim tobacco treatment engagement outcome.
Study NCT02579187 — intervention group
Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: periapical xray
Description: periapical xrays will be obtained at screening, 16 weeks and at 12 month followup time point
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PVS impression
Description: PVS impressions will be taken to plan the implant placement surgery. This will be done at the screening visit and also at 14 weeks post extraction.
Study NCT02579187 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: PVS impression
Description: PVS impressions will be taken to plan the implant placement surgery. This will be done at the screening visit and also at 14 weeks post extraction.
Study NCT05520749 — intervention group
Intervention type: DRUG
Intervention: Luspatercept
Description: Luspatercept treatment in adults with transfusion-dependent anaemia due to MDS
Study NCT05387252 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mulberry juice
Description: Mulberry is a common macrophanerophyte that can be found in fields or farms. Mulberry fruits contain a large amount of anthocyanins and a relatively small amount of pro-anthocyanins. The plant is easy to grow and the fruit price is low compared with other types of plants producing anthocyanins, and thus a reliable source for anthocyanin supplements. Current laboratory evidence has shown that specific anthocyanins can reduce inflammation status, and potentially thrombosis. One of the enzymes inhibited by specific anthocyanins is cyclooxygenase which catalyzes the synthesis of prostanoids, including thromboxane and prostaglandins. Moreover, a critical study has shown that cyanidin 3-O-glucoside, the main anthocyanin in mulberry fruit, is an allosteric regulator of interleukin-17A.
Study NCT05225051 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: skin biopsy
Description: skin biopsy
Study NCT04745286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-ketamine
Description: Patients will receive the label-covered trial agent covered by the label after premedication 5 min before induction. Agent preparation method of S-ketamine group (Group S): Draw the dosage of S-ketamine 0.25mg ·kg -1 and dilute it with normal saline to 5ml in opaque 5-ml syringes.
Study NCT04745286 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline group
Description: Patients will receive the label-covered trial agent covered by the label after premedication 5 min before induction. Normal saline group (Group N): 5ml of normal saline, labeled as study agents.