AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06369766 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Optical coherence tomography (OCT)
Description: OCT is used to measure:~* peripapillary retinal nerve fiber layer (mean thickness in μm)~* ganglion cell-inner plexiform layer (volume in mm\^3 and mean thickness in μm)~* other retinal layers (inner nuclear layer, outer plexiform layer, outer nerve layer; volumes in mm\^3 and mean thickness in μm).~The scanner laser ophthalmoscopy-function of the OCT device is used to continuously record the exact location of each participant's fixation point in relation to their fovea and thereby allows the assessment of the fixation instability.~In a subgroup of participants, the angiography-module of the OCT device is used to image the retinal blood flow and thereby allows to measure the vascular area density of the superficial retinal capillary plexus and deep retinal capillary plexus.
Study NCT06369766 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Static retinal vessel analyzer
Description: Static retinal vessel analyzer is used to determine:~* central retinal arteriolar diameter equivalents (in μm)~* central retinal venular diameter equivalents (in μm)~* arteriolar-to-venular diameter ratio
Study NCT06369766 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Dynamic retinal vessel analyzer
Description: In a subgroup of participants, the dynamic retinal vessel analyzer is used to determine the arteriolar ficker light-induced dilatation, venular ficker light-induced dilatation, and Arteriolar constriction, measured in % dilatation in comparison to baseline.
Study NCT06369766 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Laser speckle flowgraphy system
Description: In a subgroup of participants, the laser speckle flowgraphy system is used to measure the relative ocular blood flow as expressed in arbitary units of Mean Blur Rate.
Study NCT06369766 — intervention group
Intervention type: OTHER
Intervention: Questionnaire
Description: All study participants will be asked to fill in a questionnaire with various questions regarding existing eye diseases, other diseases (including vascular diseases/risk factors), and daily physical activity that could influence the results of the retinal examinations. Physical activity will be assessed using an adapted form of the standardized Global Physical Activity Questionnaire.
Study NCT06655155 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Efgartigimod PH20 SC
Description: Subcutaneous efgartigimod PH20 SC given by prefilled syringe
Study NCT06655155 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo PH20 SC
Description: Subcutaneous placebo PH20 SC given by prefilled syringe
Study NCT05949268 — intervention group
Intervention type: DEVICE
Intervention: Small bowel capsule endoscopy
Description: Patients with gastrointestinal bleeding receive small bowel capsule endoscopy after bleeding could not be located in gastroscopy or colonoscopy.
Study NCT06671782 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kegel exercises
Description: Kegel exercises without any formal training
Study NCT06671782 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic Floor Muscle Exercise Program with biofeedback
Description: Patients in the intervention arm will undergo PFME training with a physical therapist 2 times before surgery (4-6 weeks \[in person\] and 3-4 weeks \[in person\], before surgery) (within ±1 week is considered acceptable to avoid protocol violations). Patients in the intervention group will also undergo 2 PFME training sessions after surgery (3 weeks and 1.5 months after surgery).
Study NCT06671782 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaires
Description: All patients will complete the Prostate Quality of Life Survey at baseline and at 1.5, 3, and 6 months after radical prostatectomy (within ±2 weeks is considered acceptable to avoid protocol violations). This is part of the standard of care for patients undergoing prostatectomy.
Study NCT06671782 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: All patients will complete the Prostate Quality of Life Survey at baseline and at 1.5, 3, and 6 months after radical prostatectomy (within ±2 weeks is considered acceptable to avoid protocol violations). This is part of the standard of care for patients undergoing prostatectomy.
Study NCT06671782 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interviews
Description: A qualitative interview with each of the 15 patients in the intervention group to obtain information about the patient's experience. The interview will last for 30-60 min and will be conducted at 3-6 months after prostatectomy, when the patient has completed all 4 physical therapy sessions. It will cover topics related to patient involvement, satisfaction, and activation.
Study NCT05614544 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK3486
Description: HSK3486 for induction of general anesthesia
Study NCT05614544 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Propofol for induction of general anesthesia
Study NCT05614544 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intralipid
Study NCT05352607 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Nerve Stimulation (TENS)
Description: Put the patient in comfort position as long sitting on bed with a supported back and a pillow under the forearm, clean the skin by alcohol swab, setup the parameter, put a gel on electrodes then placed the negative electrode (black wire) over biceps belly and positive electrode (red wire) 3 cm distally from negative electrode , turn on TENS device .~With increase the intensity gradually until patient feel a tingling sensation (no muscle contraction) and every 10 minutes ask patient about the feeling until complete 30 minutes.
Study NCT05352607 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physiotherapy treatment
Description: Application of a hot pack for 20 minutes to enhance muscle flexibility and get overall spastic muscle relaxation. Anti-spastic muscles (elbow extensors) facilitation: tapping followed by movements (three sets of 15 repetitions per session). Hand weight-bearing with bodyweight (two 5-minute per session). Passive stretching of tight muscles (elbow flexors) is used (this must be a slow and gradual stretch for 20 seconds, followed by 20 seconds of rest, five times per session). Upper-limb active exercises should be done gradually. include (finger flexion and extension exercises, elbow and shoulder (three sets of 20 reps for each session).
Study NCT05289986 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DELSTRIGO 100Mg-300Mg-300Mg Tablet
Description: Delstrigo (300 mg of tenofovir disoproxil fumarate equivalent to 245 mg of tenofovir disoproxil, 300 mg of lamivudine and 100 mg of doravirine~- TDF/3TC/DOR)
Study NCT05289986 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DELSTRIGO 100Mg-300Mg-300Mg Tablet
Description: Delstrigo (300 mg of tenofovir disoproxil fumarate equivalent to 245 mg of tenofovir disoproxil, 300 mg of lamivudine and 100 mg of doravirine~- TDF/3TC/DOR)
Study NCT06725043 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic ultrasound
Description: Pulsed therapeutic ultrasound (1 MHz , 50% duty cycle and intensity gradually increased till the patient felt a deqi sensation).Each point was stimulated by ultrasound for 5 minutes at bilateral acupuncture points of PC6, PC7, BL60 and KI1(3 times / week for 4 weeks).
Study NCT06725043 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo therapeutic ultrasound
Description: patients were received placebo therapeutic ultrasound at bilateral acupuncture points of PC6, PC7, BL60, and KI.
Study NCT06725043 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physical therapy program
Description: Strengthing exercise, balance training, stretching exercises and home exercise program and education
Study NCT06725043 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Traditional physical therapy program
Description: Strengthing exercise, balance training, stretching exercises and home exercise program and education
Study NCT06725797 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: wound hygiene with hypothermal sulfurous water by packs
Description: GROUP A: After dressing removal, the wound is exposed. Sulphur thermal water at spring temperature (23°C) is applied for 20 minutes on the untreated wound by packs on non woven gauzes entirely covering the area. Eventually, if dried, gauzes are externally watered with additional sulphurous thermal water during the 20 minutes. After water application the wound follows the other 3 steps of the wound hygiene protocol: non viable tissue removal, edges reactivation and dressing. Non interactive dressings, just for wound moisture management, are used on cleaned wound/s. Dressing fixation, elastic bandages or off-load will be provided when required. the intervention will be repeated every 48 hours for both arms.
Study NCT06725797 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: wound hygiene with hypothermal sulfurous water by limb full immersion
Description: GROUP B: After dressing removal, the wound is exposed. Sulphur thermal water at spring temperature (23°C) is applied for 20 minutes on the untreated wound by limb full immersion in a limb tub. After the immersion, the wound follows the other 3 steps of the wound hygiene protocol: non viable tissue removal, edges reactivation and dressing. Non interactive dressings, just for wound moisture management, are used on cleaned wound/s. Dressing fixation, elastic bandages or off-load will be provided when required. the intervention will be repeated every 48 hours for both arms.
Study NCT06727058 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pandemic flu H5 mRNA vaccine
Description: Pharmaceutical Form: Suspension for injection~Route of Administration: Intramuscular (IM)
Study NCT06727058 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical Form: Liquid solution for injection~Route of Administration: Intramuscular (IM)
Study NCT06726395 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Penicillin G_1200mg
Description: benzylpenicillin preferred dosing 1gx4
Study NCT06726395 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cloxacillin
Description: cloxacillin 2gx4
Study NCT06725862 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Retrolaminar Block (RLB)
Description: This intervention involves administering 0.25% bupivacaine (0.1 mL/kg) into the retrolaminar space at the L4 vertebral level using a 22-G insulated needle under ultrasound guidance in pediatric patients after induction of general anesthesia.
Study NCT06725862 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Caudal Block (CB)
Description: This intervention involves administering 0.125% bupivacaine (1 mL/kg, maximum 20 mL) into the sacral canal using a 22-G insulated needle under ultrasound guidance in pediatric patients after induction of general anesthesia.
Study NCT06725901 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Web-Based Application
Description: The intervention involves the DIAGEN-IA platform, a diagnostic support tool designed to identify pediatric neurological diseases with a genetic basis. Using a Bayesian network model and integrating ontologies such as ORDO, HPO, and HOOM, DIAGEN-IA links phenotypic data entered by physicians to suggested diagnoses and tests. Pediatric neurologists will be trained to use the platform during a 12-month intervention. DIAGEN-IA allows clinicians to input clinical and diagnostic data, generating differential diagnoses and recommended tests, with results exportable in PDF for integration into medical records. Platform usage will be tracked, including login frequency, time spent, and evaluations performed.
Study NCT04984304 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle modifications and Antireflux diet
Description: Patients in Arm 1 - mild cough only slightly worsening the quality of life (VAS 1-3) will undergo treatment using lifestyle modifications and an Antireflux diet for 3 months.
Study NCT04984304 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Extraesophageal reflux diagnostic
Description: Patients in Arm 2 - moderate and severe cough that significantly worsen the quality of life (VAS 4-10) will undergo extraesophageal reflux diagnostics consisting of esophageal 24-hour pH/Impedance Reflux Monitoring and peptest study on fasting
Study NCT06285019 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TOMOX-HAIC
Description: Oxaliplatin 85mg/m\^2 plus Raltitrexed 3mg/m\^2, 21 days for a cycle
Study NCT06285019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 200mg, ivgtt, d1, 21 days for a cycle
Study NCT06285019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: 7.5mg/kg, ivgtt, d1, 21 days for a cycle
Study NCT04747691 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bedside gastric ultrasound
Description: Bedside ultrasound exam of the stomach
Study NCT05711459 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bicyclol tablets
Description: Take Bicyclol tablets for the treatment of liver injury.
Study NCT05423665 — intervention group
Intervention type: OTHER
Intervention: sample collection
Description: blood sample at 21 weeks of gestation clips of the fetal heart at 21 weeks of gestation, 30 weeks of gestation and 1-3 days after birth collection of umbilical cord blood at birth collection of the placenta at birth
Study NCT05688696 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orelabrutinib (Low Dose)
Description: Subjects will be administered with lower dose of Orelabrutinib orally once daily in combination with SOC therapy
Study NCT05688696 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orelabrutinib (High Dose)
Description: Subjects will be administered with higher dose of Orelabrutinib orally once daily in combination with SOC therapy
Study NCT05688696 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Orelabrutinib Placebo
Description: Subjects will be administered with Orelabrutinib Placebo orally once daily in combination with SOC therapy
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tumor biopsy
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Biopsy
Description: Undergo bone marrow biopsy
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo SPECT/CT
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET scan
Study NCT06508463 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter
Description: Given IV
Study NCT04749901 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Psycho-emotional and semiological measures
Description: Surveys, interviews and measures
Study NCT05783011 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: Electroacupuncture was applied bilaterally to the LI4, ST5 and ST6 acupuncture points before and after periodontal flap surgery
Study NCT05783011 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: periodontal flap surgery
Description: periodontal flap surgery
Study NCT05783011 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: periodontal flap surgery
Description: periodontal flap surgery
Study NCT05710367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin 10mg Tab
Description: Forxiga® as an add-on treatment in patients with renal and/or cardiac association FD in an exploratory framework.
Study NCT05710367 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: matched oral drug. Placebo tablet will have the same color, taste, smell and package as the verum tablet
Study NCT05200975 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Venapunction
Description: Three venapunctures within a period of 72 hours, containing a maximum of 18ml of venous blood in total.
Study NCT05671042 — intervention group
Intervention type: OTHER
Intervention: Patients with Upper excretory tract tumors
Description: Standard of care for patients with Sezary Syndrome
Study NCT06191562 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tympanostomy tube
Description: Participants will receive an ear tube in the usual location (anterior-inferior) in one ear and a new location (posterior-inferior) in the other ear during surgery.
Study NCT05784467 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Methamphetamine, PrEP, and Intersectional Stigma (eMPrISe) study
Description: Group behavioral intervention with 12 weekly sessions lasting 2 hours focusing on coping, resistance, and resilience.
Study NCT06377449 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound examination of the lungs
Description: Experimental: Standard ultrasound examination of the lungs based on modified BLUE protocol Active Comparator: Standard ultrasound examination of the lungs based on modified BLUE protocol
Study NCT06377449 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound examination of the lungs
Description: Experimental: Standard ultrasound examination of the lungs based on modified BLUE protocol Active Comparator: Standard ultrasound examination of the lungs based on modified BLUE protocol
Study NCT06629038 — intervention group
Intervention type: BEHAVIORAL
Intervention: observation alone
Description: observation of maximal mouth opening, lateral excursion, and range of motion of shoulder abduction, neck joint
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Probiotic
Description: Treatment with capsules with 10\^9 CFU/ day of Limosilactobacillus fermentum CECT5716 during 6 months
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: Treatment with capsules with 10\^9 CFU/ day of Limosilactobacillus fermentum CECT5716 during 6 months
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Prebiotic
Description: Treatment with capsules 500 mg/capsule/day of olive leaf extract, containing 35% oleuropein during 6 months
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Prebiotic
Description: Treatment with capsules 500 mg/capsule/day of olive leaf extract, containing 35% oleuropein during 6 months
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Synbiotic
Description: A pill with a combination of prebiotic and probiotic at the same doses during 6 months
Study NCT06722443 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Synbiotic
Description: A pill with a combination of prebiotic and probiotic at the same doses during 6 months
Study NCT06717256 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: training
Description: The diabetes education booklet is a collection of information designed by the researcher. These interventions will continue for 1.5 months, with a total of 6 sessions for each type 2 DM individual, lasting approximately 120 minutes (2 hours per week and 12 hours in total after 6 weeks), and will be carried out as reminders afterwards. In these sessions, agendas will be created appropriately on regular eating habits, physical activity, regular monitoring of blood sugar, compliance with treatment, problem-solving ability, coping strategies and minimizing risks, conflicts regarding self-management and skin care behaviors of the patient will be tried to be resolved, the patient's suitability and adaptation to the change phase will be determined, their willingness to change will be questioned, and the change plan will be helped in the matters of care and self-management.
Study NCT06724406 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Skills Training Session Quantity: 5
Description: The number of family skills training sessions administered: 5 sessions
Study NCT06724406 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Skills Training Session Mode: In-person
Description: The mode of administration of family skills training sessions: in person or online
Study NCT06508463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single Photon Emission Computed Tomography
Description: Undergo SPECT/CT
Study NCT06508463 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Given IV
Study NCT06724406 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Skills Training Content: Communication
Description: The content of family skills training sessions administered focused on communication and conflict resolution : communication and conflict resolution
Study NCT06724406 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Skills Training Content: Cohesion
Description: The content of family skills training sessions administered focused on cohesion: cohesion or no cohesion
Study NCT06724406 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Skills Training Session Quantity: 10
Description: The number of family skills training sessions administered: 10 sessions
Study NCT06508463 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Given IV
Study NCT06040944 — intervention group
Intervention type: DRUG
Intervention: antipsychotic drugs inducing hyperprolactinemia
Description: not exposed