AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04237025 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nordic walking exercise
Description: Supervised Nordic Walking (NW) exercise will be conducted in a small group setting with a 2:1 participant to trainer ratio providing individualized training instruction. Training will be conducted for a total of 14 one-hour sessions over a 6-week period. Training will take place at an outdoor community track with progression tasks on hills or grassy terrain. The one-hour training sessions will include a 10-minute warm-up period, 45 minutes of individualized NW training, and a 5-minute cool down period. The target training duration goal for NW exercise will be 45 minutes of continuous walking at moderate intensity based on target heart rate and Rating of Perceived Exertion. NW exercise program will be customized and progressed for each participant by trainers with ongoing assessment of participant's gait pattern, NW technique, and exercise responses during the training sessions. Group comradery and accountability will be facilitated through training in small group training context.
Study NCT05470049 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection and SHR0410 Injection
Description: Treatment group A: SHR8554 Injection and SHR0410 Injection; high dose
Study NCT05470049 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection and SHR0410 Injection
Description: Treatment group B: SHR8554 Injection and SHR0410 Injection; low dose
Study NCT05470049 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SHR8554 Injection and Placebo for SHR0410 Injection
Description: Treatment group C: SHR8554 Injection and Placebo for SHR0410 Injection
Study NCT06115629 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surveillance protocol
Description: Imaging surveillance will entail a computed tomography scan of the chest, abdomen and pelvis, as well as clinical review, every 6 months for 36 months post surgery along with an endoscopy at 12 months post surgery.
Study NCT05630820 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bepirovirsen
Description: Bepirovirsen will be administered.
Study NCT05630820 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo will be administered.
Study NCT05732051 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nicotinamide Riboside
Description: Nicotinamide Riboside 500mg b.i.d as long as the patient is receiving anthracycline therapy
Study NCT05732051 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo b.i.d as long as the patient is receiving anthracycline therapy
Study NCT05952687 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Idasanutlin
Description: Patients will receive idasanutlin dosed once daily on Days 1-5 of a 28-day cycle starting with 80% of the RP2D determined in the ongoing pediatric iMATRIX trial using single agent idasanutlin.
Study NCT05952687 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Idasanutlin
Description: Patients will receive idasanutlin dosed once daily on Days 1-5 of a 28-day cycle starting with the RP2D determined in the dose-finding/safety phase.
Study NCT05952687 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Patients will receive selinexor on Day 4 of each of the first 3 weeks of a 28-day cycle. Selinexor will be skipped on week 4 of each cycle.
Study NCT05978973 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Elemental Diet
Description: . Elemental diets contain all daily required vitamins, micronutrients and macronutrients. The ingredients are readily digestible (carbohydrates, amino acids and medium chain fatty acids) and are absorbed within the proximal small bowel. One main disadvantage of elemental diets such as Vivonex is their unpalatability3 which has limited their use.
Study NCT04929405 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ADAPT
Description: ADAPT, is multi-modal to promote a targeted approach to individual parental bereavement experiences and is not time or geographically limited. ADAPT is based on the theoretical foundations of the Adaptive Leadership (AL) framework. Our interdisciplinary team developed a web-based, multi-modal intervention, labeled ADAPT, that incorporates varied self-management strategies including: A: Asking for assistance (option to connect with child's healthcare team); DA: Developing Adaptive ability (self-management tools: e.g. stress reduction, legacy building); P: Accessing Pertinent online resources (grief support networks/websites); and T: Tracking one's health (self-administered surveys for grief, sleep, anxiety, and depression). Parents can download ADAPT on any digital device (phones/computers) using a Quick Response (QR) bar code or weblink.
Study NCT04997447 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Step-reduction/Exercise Rehab
Description: 2-week limited daily steps (\<2000), and then 4 weeks of typical strength+endurance exercise for older adults
Study NCT04998760 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATG-008
Description: ATG-008 will be orally administered at 30 mg QD combined with chemotherapies. And about 8-12 subjects plan in each cohort.
Study NCT04998760 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATG-010
Description: ATG-010 will be orally administered at 30 mg QD and 80 mg QW combined with chemotherapies. And about 8-12 subjects plan in each cohort.
Study NCT05851703 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual therapy application
Description: In lower cervical lateral flexion problems, pushing technique will be applied with instrument support from the articular pillar part of the superior vertebra on the side where the limitation is present.~In lower cervical lateral flexion problems, instrument-assisted pushing technique will be applied from the articular pillar part of the superior vertebra on the side where the limitation is present.
Study NCT05851703 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive Neuromuscular Facilitation
Description: With the rhythmic initiation technique, it is to teach the movement to the person, to improve the feeling of movement, coordination and to help relaxation. With rhythmic initiation, we want the patient's initial passive and then active participation to understand the movement, the direction and rhythm of the movement. After people actively participate, they can use active joint movement.
Study NCT05446233 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] Antaitavir Hasophate
Description: 100 mg suspension containing 200µCi of \[14C\] Antaitavir Hasophate
Study NCT06261801 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medication Group
Description: Participants in the medication group would take 150-mg pregabalin capsules (manufactured by Pfizer Pharmaceuticals Co., Ltd) orally twice daily (total daily dose, 300 mg) for 4 weeks.
Study NCT06261801 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EA Group
Description: Acupoints selection: Ashi acupoint, Sibai acupoint (ST2), Xiaguan acupoint (ST7), and Dicang acupoint (ST4) on the affected side. Acupoints for the diseased branches (all taken from the affected side): eye branch and Tongziliao point (GB1), the maxillary branch is taken from the Quanliao point (SI18), and the mandibular branch is taken from the Jiache point (ST6).Shenting point (DU24), Baihui point (DU20), Hegu point (LI4), Waiguan point (TE5), Yanglingquan point (GB34), and Taichong point (LR3) on the affected side Operation: The EA apparatus will be applied on the Ashi point and (LI4 - TE5). The treatment will last for 30 minutes and the electrical stimulation will be set as 2/100Hz in frequency.
Study NCT06261801 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EA+Medication Group
Description: Participants in the EA+Medication group would receive both EA and medical treatement. The acupoints and their location, needles, the settings of the EA device are the same as EA Group's; in the meanwhile, the medication and its dosage is the same as Medication Group's.
Study NCT05258604 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: argon plasma coagulation
Description: APC Standard APC equipment will be used, consisting of a high-frequency electrosurgical generator (ICC 350; ERBE, Tübingen, Germany), an argon source which is regulated automatically (APC 300) and APC probe.
Study NCT06610721 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Urine Biomarkers
Description: At baseline midstream urine will be collected in a sterile urine container.
Study NCT06349746 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: therapeutic exercises
Description: stretching exercise to posterior capsule and progressive resistance exercise for rotator cuff and scapula stabilizer and home exercise 3 sessions per week for 6 week.
Study NCT06349746 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: mobilization exercise
Description: cervical unilateral antero-posterior mobilization and thoracic central postro-anterior mobilization
Study NCT06242860 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ELM
Description: Treatment of dry eye with ELM device
Study NCT05356299 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Magnetictape bandage application
Description: The Magnetic Tape bandage will be placed by the patient's care team and will be placed in the anterior superior part of each hemithorax, matching the large vessels and lymph nodes, in the posterior part of the thorax in the paravertebral area from C3 to T9 and in the subcostal region, following the direct innervation of the thorax and shoulder girdle, as well as the dorsal levels with lateral horns that control the vascularisation of the thorax and shoulder girdle.
Study NCT04744168 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Puncture of 5 points 4GI, 6RP, 34VB, 36E, 3F
Study NCT04744168 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Acupuncture
Description: Puncture of point HM
Study NCT06039631 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: In the surgical group, patients will undergo curative surgery for laryngeal/hypopharyngeal cancer along with cervical lymph node dissection. Organ preservation surgery is recommended.
Study NCT06039631 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Radiation
Description: In the surgical group, depending on postoperative pathology results, adjuvant radiotherapy or concurrent radiochemotherapy may be administered as deemed necessary. If postoperative pathology indicates extracapsular invasion of lymph nodes or positive surgical margins, concurrent radiochemotherapy based on cisplatin is recommended.~In the concurrent radiochemotherapy group, patients will undergo target delineation based on the scope before induction chemotherapy. Radiotherapy will be administered at a total dose of 70 Gy over 35 fractions, and concurrent chemotherapy will involve weekly administration of cisplatin at a dosage of 30 mg/m².
Study NCT06039631 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation
Description: In the surgical group, depending on postoperative pathology results, adjuvant radiotherapy or concurrent radiochemotherapy may be administered as deemed necessary. If postoperative pathology indicates extracapsular invasion of lymph nodes or positive surgical margins, concurrent radiochemotherapy based on cisplatin is recommended.~In the concurrent radiochemotherapy group, patients will undergo target delineation based on the scope before induction chemotherapy. Radiotherapy will be administered at a total dose of 70 Gy over 35 fractions, and concurrent chemotherapy will involve weekly administration of cisplatin at a dosage of 30 mg/m².
Study NCT06039631 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Toripalimab
Description: In the both groups, starting three weeks after the completion of radiotherapy, patients will receive adjuvant immunotherapy using a specific protocol of toripalimab at a dose of 240 mg every 3 weeks for a total of 8 cycles.
Study NCT06039631 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: In the both groups, starting three weeks after the completion of radiotherapy, patients will receive adjuvant immunotherapy using a specific protocol of toripalimab at a dose of 240 mg every 3 weeks for a total of 8 cycles.
Study NCT05696587 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal rehabilitation
Description: The multimodal rehabilitation program included comprehensive therapy 5 times a week during the 4 weeks between assessments. The therapy consists of:~* Individual physical therapy focused on improving range of motion and alleviating pain in the affected limb;~* Mechanical desensitization;~* Transcutaneous electric nerve stimulation (TENS) electrotherapy;~* Aquatherapy (arm or leg whirlpool bath of the affected extremity);~* Graded Motor Imagery, including the Recognise™ app and mirror therapy;~* Psychoeducation on relaxation and coping with chronic pain.
Study NCT06303271 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vagus Nerve Stimulation (VNS) and Caw Thorne Cooksey
Description: Study will be conducted after the approval of Ethical review board. After the initial evaluation will be done on participants underlying eligibility criteria. Experimental group will received intervention of 30 minutes daily for 4 weeks (16 sessions). Assessment was done at the baseline, after 2 weeks and after 4 weeks. Intervention Group received non-invasive vagus nerve stimulation at left auricle (because of anatomy of vagus nerve as right VN innervate SA node which is regulating heartbeat and left VN innervates AV node which is responsible for controlling timing of heartbeat) of ear. VNS group received vagus nerve stimulation via Med Fit vagus nerve stimulator at auricle of left ear only as stimulation of right auricular branch of vagus nerve can result in bradycardia. Frequency of stimulation was kept between 15-30Hz. Intensity was gradually increased according to patient's tolerance. The participant was able to withdraw from the trial if he could not tolerate the stimulation
Study NCT06303271 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Caw Thorne Cooksey
Description: Study will be conducted after the approval of Ethical review board. After the initial evaluation will be done on participants underlying eligibility criteria. The control group will intervention of 30 minutes daily for 4 weeks (16 sessions). Caw Thorne Cooksey exercises were carried out during the stimulation of vagus nerve. Although no adverse effects had been reported during the stimulation of left auricular branch of vagus nerve but a pulse oximeter was used during the stimulation to monitor the heart rate.
Study NCT05784831 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Reappraisal training
Description: The EMI developed and tested here is based on theoretical and empirical findings and consists of several items and repeated training using various individual scenarios from participants' life that will be presented to participants via an app on their smartphones.
Study NCT05784831 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ecological Momentary Assessment
Description: The EMA tested here collects data on participants' mood and behavior.
Study NCT04940403 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Burt
Description: 18 one-hour sessions of unimanual upper-limb tasks during robot-assisted training with the Burt.
Study NCT04940403 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Burt + BurtVision
Description: 18 one-hour sessions of combination of unimanual and bimanual upper-limb tasks during robot-assisted training with the BurtVision.
Study NCT05032989 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraction of mandibular 3rd molar via Cowhorn forcep technique
Description: Cowhorn forceps technique used to extract the tooth results in less post operative pain and swelling also it makes the extraction easier.
Study NCT05032989 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extraction of mandibular 3rd molar via conventional technique
Description: Conventional method of extraction uses dental elevator and forceps resulting in post operative pain and swellig.
Study NCT05007080 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad26.COV2.S
Description: Ad26.COV2.S will be administered as intramuscular (IM) injection.
Study NCT05258604 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endoscopic band ligation
Description: endoscopic band ligation will be carried out using a Saeed Multi-Band Ligator (Cook Medical, WinstonSalem, NC), and ligation bands were placed on the GAVE.
Study NCT05184712 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivonescimab (SMT112 or AK112) Injection
Description: Subjects will receive Ivonescimab (SMT112 or AK112) Plus Pemetrexed and Carboplatin via intravenous infusion (IV) Q3W, up to 4 cycles. Afterward, Ivonescimab (SMT112 or AK112) Plus Pemetrexed will be used for maintenance treatment (administered on Day 1 of each cycle, Q3W) up to 2 years.
Study NCT05184712 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Injection
Description: Subjects will receive Placebo Plus Pemetrexed and Carboplatin via intravenous infusion (IV) Q3W, up to 4 cycles in treatment periods per the randomization schedule. Afterward, Placebo Plus Pemetrexed will be used for maintenance treatment (administered on Day 1 of each cycle, Q3W) up to 2 years.
Study NCT06292468 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physical therapy
Description: This group received 30 minutes of muscle stretching (quadriceps, gastrocnemius, hamstrings, tibialis), bilateral ankle strengthening, gait training and foot care guidelines, 3 times a week for a duration of six weeks.
Study NCT06292468 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Plantar cutaneous sensory stimulation
Description: This group received 45 minutes of plantar cutaneous sensory stimulation, TENS, muscle stretching (quadriceps, gastrocnemius, hamstrings, tibialis), bilateral ankle strengthening, gait training, and foot care guidelines, 3 times a week for a duration of six weeks.
Study NCT06295198 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single lep drop jump test
Description: All evaluations will be repeated before and after the treatment.
Study NCT05365360 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LaserCap SD
Description: LaserCap SD
Study NCT05365360 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham LaserCap
Description: Sham LaserCap
Study NCT05365360 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LaserCap HD+
Description: LaserCap HD+
Study NCT05734469 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Forefoot bone surgery
Description: Elective forefoot bone surgery under popliteal sciatic nerve
Study NCT05734469 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Forefoot bone surgery
Description: Elective forefoot bone surgery under an ankle block
Study NCT04677829 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PNT001
Description: 30 minute infusion for PNT001 1000mg; 60 minute infusion for PNT001 4000mg
Study NCT04677829 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: PNT001
Description: 30 minute infusion for PNT001 1000mg; 60 minute infusion for PNT001 4000mg
Study NCT04677829 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: %5 dextrose for infusion
Description: 30 min placebo infusion for 1000mg; 60 minute placebo infusion for 4000mg
Study NCT04677829 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: %5 dextrose for infusion
Description: 30 min placebo infusion for 1000mg; 60 minute placebo infusion for 4000mg
Study NCT05697952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E1K 1,200 ㎍/joint
Description: Injection of E1K 1,200 ㎍/joint/ml on target lesion
Study NCT05697952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E1K 2,400 ㎍/joint
Description: Injection of E1K 2,400 ㎍/joint/ml on target lesion
Study NCT05697952 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Injection of 3ml saline on target lesion
Study NCT04775199 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language Intervention
Description: The examiners will target vocabulary and grammar in the context of preschool science instructions.
Study NCT05347368 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control group (conventional therapy)
Description: Physical therapy will be performed using physical agent modality that include hot pack (15 min), and therapeutic exercises (5 repetition per set, 2 sets each session) therapeutic exercises include spinal extension exercise, prone hip extension exercise, posterior pelvic tilt, cat-camel exercise
Study NCT05347368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control group (conventional therapy)
Description: Physical therapy will be performed using physical agent modality that include hot pack (15 min), and therapeutic exercises (5 repetition per set, 2 sets each session) therapeutic exercises include spinal extension exercise, prone hip extension exercise, posterior pelvic tilt, cat-camel exercise
Study NCT05347368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Primal Reflex release Technique
Description: The SI/Lumbar release Iliopsoas release Piriformis release Hamstring release Gastrocnemius release
Study NCT06414707 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vonoprazan, Amoxicillin and Levofloxacin
Description: Group (1) included 160 patients received Vonoprazan 20 mg oral once daily + Levofloxacin 500 mg oral once daily + Amoxicillin 1 gm oral twice daily for 14 days.