AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05602779 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tVns Program
Description: Participants will use the Neuvana Xen device 30 minutes a day for 3 days. The device delivers stimulation through the left ear via an ear bud. Participants can use the device at any time of day.
Study NCT05602779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Phone App Program
Description: Participants will have access to a specially designed phone app in order to play a game designed for this study. Approximately half of the participants will be able to connect with a fellow participant who is matched as their peer for social support.
Study NCT06323187 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cervical Sampling
Description: Each participant will provide a sample of fluid or mucus collected from the uterine endocervix.
Study NCT06629545 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: irrigation activation with PUI
Description: The irrigation solution was used by adapting an ultrasonic tip (IRRI S 21/25; VDW, Munich, Germany) to an ultrasonic device. The power setting of the ultrasonic device was 30% (VDW Ultra; VDW, Munich, Germany). The tip was activated a total of three times, with each cycle lasting 20 s and involving the use of 1 ml of 2.5% NaOCl. Then, 2 ml of 17% EDTA solution was activated for 1 min as describe above. The ultrasonic tip was placed 1 mm behind the working length without touching the canal walls.
Study NCT06629545 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: irrigation with sonic activation
Description: A suitable-size activator tip (#25/.04) attached to an EndoActivator sonic handpiece (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) was inserted into the canal 1 mm short of the working length. 3 ml of 2.5% NaOCl solution was activated in three periods of 20 s (1 ml of 2.5% NaOCl in each cycle). Then, the same procedure was repeated with 2 ml of 17% EDTA solution.
Study NCT06631404 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: renal doppler
Description: doppler srudy on renal arteries bilaterally , and detection of RI of renal artery
Study NCT06629116 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Patients with AIS receive intravascular therapy, and within 10 minutes after the surgery, they are administered 100ml of 20% human albumin intravenously (infused within 30 minutes).
Description: Whether to administer albumin to AIS patients after intravascular thrombectomy and reperfusion.
Study NCT06628427 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MoCA Test
Description: MoCA (Montreal Cognitive Assessment or The MoCA Test) was validated as a highly sensitive tool for early detection of mild cognitive impairment (MCI) in hundreds of peer-reviewed studies since 2000. MoCA has been widely adopted in clinical settings and used in academic and non-academic research around the world. The sensitivity of MoCA for detecting MCI is 90%, compared to 18% for the MMSE. Prospective participants meeting the eligibility criteria, as determined by the Montreal Cognitive Assessment (MoCA) test, will be invited to the Brain- Computer Interface (BCI) laboratory at the Kroto Research Centre on the University of Sheffield north campus to participate in the study.
Study NCT06628427 — intervention group
Intervention type: DEVICE
Intervention: Random Dot Motion (RDM) task
Description: Random Dot Motion task (RDM) has been widely used in research on spatial attention, and decision-making ability, etc., and its results (accuracy and reaction time) can be used as indicators to detect spatial attention. During the assessment, participants were required to monitor a series of dots in constant random motion on the screen. The dots sometimes moved coherently together to the left or right, and participants were required to press the left mouse button when they perceived them moving to the left and the right mouse button when they observed them moving to the right. We are going to use the motion coherence level of 50%. The higher the coherence level, the greater the number of dots moving together, and the combination of the moving direction and coherence level of the dots appear randomly during the task.
Study NCT06628427 — intervention group
Intervention type: DEVICE
Intervention: P300-BCI task without feedback
Description: Two different speller matrix sizes: 3×3 and 5×5, two inter-stimulus intervals (ISIs): 117ms (i.e., commonly used ISI for healthy adults) and 175ms (i.e., 50% longer than the widely used ISI) and two spelling words (QUICK and JUMP) are designed in this experiment to explore the calibration accuracy of these eight parameter combinations in the young and old groups and obtain the best parameter combination. The matrix contains letters and digits, and the target letters will be displayed below the matrix letter by letter. When the speller runs, the rows and columns in the matrix will flash 15 times each randomly. Each flash will last for 55ms, and the subsequent ISI will last for different times according to different parameter designs. Participants only need to focus on the target letter and silently count the number it flashes, as flashing target letters can generate P300 if well attended.
Study NCT06630065 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: fMRI with emotional task and pupillometry
Description: Anatomical and functional magnetic resonance imaging (fMRI) imaging sequences with pupillometry (\~90 min)~A functional sequence - Task (\~20min):~* Emotional task in fMRI: Instructions: simply look images, then evaluate the emotions triggered at the end of each block; rating on a valence and intensity scale and intensity (arousal) scale.~* Experimental conditions: positive, negative and neutral~* Paradigm: block validated image banks: IAPS, GAPED, EMOPICS, OASIS, etc. Pupillometry: In order to collect objective data on emotional bias, we will use pupillometry (or eye-tracking) during functional MRI sequences.
Study NCT06630065 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: fMRI with emotional task and pupillometry
Description: Anatomical and functional magnetic resonance imaging (fMRI) imaging sequences with pupillometry (\~90 min)~A functional sequence - Task (\~20min):~* Emotional task in fMRI: Instructions: simply look images, then evaluate the emotions triggered at the end of each block; rating on a valence and intensity scale and intensity (arousal) scale.~* Experimental conditions: positive, negative and neutral~* Paradigm: block validated image banks: IAPS, GAPED, EMOPICS, OASIS, etc. Pupillometry: In order to collect objective data on emotional bias, we will use pupillometry (or eye-tracking) during functional MRI sequences.
Study NCT06630065 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral task with emotional facial expressions
Description: Description of the recognized emotion joy - sadness. Test to assess the hedonic value of an olfactory stimulus (10 min)
Study NCT06630065 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Behavioral task with emotional facial expressions
Description: Description of the recognized emotion joy - sadness. Test to assess the hedonic value of an olfactory stimulus (10 min)
Study NCT06630065 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Biological investigation
Description: Standard biological assessment, immuno-inflammatory profile and the association of 8 mRNA editing variants
Study NCT06630065 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Biological investigation
Description: Standard biological assessment, immuno-inflammatory profile and the association of 8 mRNA editing variants
Study NCT06629805 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Aureobasidium pullulans produced β-glucan
Description: Aureobasidium pullulans produced β-glucan 1,000 mg/day for 12 weeks
Study NCT06629805 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 1,000 mg/day for 12 weeks
Study NCT06632145 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cog Fun Ageing intervention
Description: Cog Fun Ageing is a group-based occupation-centered intervention aimed at promoting positive occupational experiences despite cognitive challenges in day to day life. The intervention includes 14 weekly 120-minute group sessions led by experienced occupational therapists. Sessions incorporate learning about the bio-psycho-social factors of SCD and strategies to manage and cope with occupational challenges resulting from SCD.
Study NCT06713616 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Racemic ketamine
Description: Ketamine will be given intravenously. Per FDA guidance, the max dose of ketamine will be 60mg per day, with a total lifetime limit of 8 doses. Ketamine will be infused over 40 minutes.
Study NCT06713616 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spravato (Esketamine)
Description: Spravato® (Esketamine) will be given intranasally. For esketamine, the dose will be between 56 and 84mg, according to the FDA label for the drug. Allowances will be made for patients who have difficulty tolerating these doses to be dosed at 28mg in subsequent treatment sessions.
Study NCT05974072 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: The pharmacological treatment will be individualised according to pain intensity, contraindications and the appearance of adverse effects.
Study NCT05974072 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PAINDOC Program
Description: The PAINDOC Program consists in:~* Therapeutic education: The therapeutic education block consists of two parts: an education session called Empowered Relief (ER) and two pain neuroscience education (NDT) sessions.~* Psychotherapy: The psychotherapy part consists of one group session of one hour, face-to-face and with groups of up to 15 people, given by the psychologist of the pain unit.~* Mindfulness Meditation: The Mindfulness Meditation consists of one group session of one hour, face-to-face and with groups of up to 15 people. These are given by a nurse from the pain unit. T~* Therapeutic exercise: The therapeutic exercise module consists of three sessions of one hour each, face-to-face, with small groups of between 6 and 10 patients, and given by the physiotherapist of the pain unit.
Study NCT05971225 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: remote monitoring only
Description: remote monitoring only can replace in-office device monitoring
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: First Reference product (dextrose, containing 25 g of carbohydrates)
Description: Reference dextrose solution containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Second Reference product (dextrose, containing 25 g of carbohydrates)
Description: Reference dextrose solution containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Third Reference product (dextrose, containing 25 g of carbohydrates)
Description: Reference dextrose solution containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: High protein tube feed
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: High-protein tube feed with additional amino acid
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Oral Nutritional Supplement for diabetes patients
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Oral Nutritional Supplement for diabetes patients (new formula)
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: ONS for disease related malnutrition
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT05179031 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Plantbased ONS for disease related malnutrition
Description: Nutritional product containing 25 g of available carbohydrates
Study NCT04898907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANG-3777 (Therapeutic Dose)
Description: Arms assigned to this intervention will receive 2 mg/kg, IV, Fasted
Study NCT04898907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANG-3777 (Supra-therapeutic Dose)
Description: Arms assigned to this intervention will receive 6 mg/kg, IV, Fasted
Study NCT04898907 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Arms assigned to this intervention will receive normal saline, IV, Fasted
Study NCT04898907 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin Hydrochloride
Description: Arms assigned to this intervention will receive 400 mg, Oral, Fasted
Study NCT06224699 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Toothpaste Product
Description: Use of toothpaste with or without sodium carbonate at 67%
Study NCT06224699 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toothpaste Product
Description: Use of toothpaste with or without sodium carbonate at 67%
Study NCT05602779 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: tVNS and Phone App Program
Description: Participants will have both the Neuvana Xen Device and the full version of our program's phone app. They will use the device and full app access for 30 days.
Study NCT05602779 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Enhanced Treatment as Usual
Description: Participants will have access to our program's phone app so the can play the game and will be called weekly to complete risk assessments.
Study NCT05971225 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: remote monitoring only
Description: remote monitoring only can replace in-office device monitoring
Study NCT06518005 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imlifidase
Description: Imlifidase: single administration (dose is confidential), Lyophilized powder for concentrate for solution for infusion
Study NCT06518005 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GNT0003
Description: GNT0003: single administration 5E+12 VG/kg, Sterile concentrate for solution for infusion
Study NCT05367427 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Heat treated postbiotic Bifidobacterium Longum consumption
Description: Regular consumption in breakfast of heat treated postbiotic B. longum
Study NCT05367427 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin
Study NCT04623190 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Wait-List Control
Description: -Will receive routine clinical care. After completion of follow-up measures, control participants will receive a behavior change prescription via the PREVENT tool
Study NCT04623190 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PREVENT tool
Description: -PREVENT is a novel Health Information Technology tool designed to promote physical activity and healthy food intake among overweight/obese patients at the point of care. PREVENT automates the delivery of personalized, evidence-based behavior change recommendations and provides an interactive map of community resources to help providers link patients to resources in their community.
Study NCT05380219 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dual task strength training
Description: strength training and dual task
Study NCT05380219 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: dual task strength training
Description: strength training and dual task
Study NCT06059417 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 2x2 inch piece of 3M microfoam adhesive
Description: A 2x2 inch piece of 3M microfoam adhesive will be applied to the medial aspect of the subject's upper arm.~The adhesive will remain in place for 48 hours at which time an investigator will remove the adhesive and assess the study area. A numerical value will be assigned based on the Cutaneous Irritancy Scoring System (CISS). The study site will be compared to the contra-lateral upper extremity at the end of the 48 hour period.
Study NCT06285708 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prolonged exposure
Description: PE therapy is a manualized cognitive behavioral therapy consisting of imaginal exposure (repeated recounting of the most disturbing traumatic memory) followed by processing thoughts and feelings related to the imaginal experience; in-vivo exposure (approaching trauma-related situations); psychoeducation about PTSD; and controlled breathing training. Between sessions, participants listen to audio recordings of the imaginal recounting daily and complete in-vivo exercises. Typically, PE is delivered weekly for 10-12, 90-minutes sessions. For this study, participants will complete daily 60-minute sessions for 10 consecutive weekdays during a 2-week period.
Study NCT06285708 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Prolonged exposure
Description: PE therapy is a manualized cognitive behavioral therapy consisting of imaginal exposure (repeated recounting of the most disturbing traumatic memory) followed by processing thoughts and feelings related to the imaginal experience; in-vivo exposure (approaching trauma-related situations); psychoeducation about PTSD; and controlled breathing training. Between sessions, participants listen to audio recordings of the imaginal recounting daily and complete in-vivo exercises. Typically, PE is delivered weekly for 10-12, 90-minutes sessions. For this study, participants will complete daily 60-minute sessions for 10 consecutive weekdays during a 2-week period.
Study NCT05088226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib combined with Chidamide.
Description: Drug: modified By/Cy conditioning regimen intensified by Ruxolitinib and Chidamide .~Day -15 # Ruxolitinib 70mg bid, Chidamide 30 mg once; Day -14 # Ruxolitinib 70mg bid; Day -13 # Ruxolitinib 70mg bid; Day -12 # Ruxolitinib 70mg bid, Chidamide 30 mg once; Day -11 # Ruxolitinib 70mg bid; Day-10# Cytarabine 4g/m2/day CI , Ruxolitinib 60mg bid; Day- 9# Cytarabine 4g/m2/day CI, Ruxolitinib 60mg bid; Day- 8 # Busulfan 0.8mg/ kg Q6h iv, Ruxolitinib 50mg bid, Chidamide 30 mg once; Day- 7# Busulfan 0.8mg/ kg Q6h iv, Ruxolitinib 50mg bid; Day-6# Busulfan 0.8mg/kg Q6h iv, Ruxolitinib 40mg bid; Day-5# Cyclophosphamide 1.8 g/m2/day CI, Ruxolitinib 30mg bid, Chidamide 30 mg once; Day-4# Cyclophosphamide 1.8 g/m2/day CI,Ruxolitinib 20mg bid; Day-3# Carmustine 250mg/m2/ day iv, Ruxolitinib 10mg bid; Day-2# Ruxolitinib 5mg bid, Chidamide 30 mg/day; Day-1# Ruxolitinib 5mg qd;
Study NCT05974800 — intervention group
Intervention type: BEHAVIORAL
Intervention: Emergency department caregivers interview
Description: The interview focuses on several parts of the emergency care process: The first part is regarding the actions that are executed during an emergency department visit. We will establish which actions are executed and why. The second part is regarding the suspected outcome for the patient. The third part will be about any potential improvements to the emergency care process for the patient.
Study NCT05640817 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pentoxifylline 400 mg SR tablets
Description: a nonspecific phosphodiesterase inhibitor, was first considered in the treatment of peripheral vascular diseases
Study NCT05640817 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cisplatin with standard hydration with normal saline
Description: chemotherapy
Study NCT01131247 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ofatumumab + bendamustine
Description: Loading dose of ofatumumab at 300mg IV with subsequent doses at 100mg IV on D1 of all cycles (maximum of 6 cycles) in combination with bendamustine 90mg/m2 on day 2 of all cycles. Neulasta 6mg SQ will also be given on day 8 of cycle 1 only.
Study NCT05241795 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Knee then Ankle rehabilitation protocol
Description: Patients will start with knee exercise program that includes~* Partial Squats: The exercise will be performed as 3 sets of 10 repetitions each day.~* Toe Raises: The exercise will be performed as 3 sets of 10 repetitions each day.~* Stationary bike will be used (10-15 minutes /day) when the patients can bend their knees at least 100 degrees, as cycling is considered as an excellent conditioning and building exercise for the quadriceps muscles. As the patient's ability to pedal the bike with the operative leg improved, the therapist will increase the resistance.~* Hamstring exercises: After 6 weeks, the hamstring muscles will be exercised by the patient pulling the heel back producing a hamstring contraction.~Then, Patients will start ankle exercises program that includes:~* Standing calf raises~* Foot lift~* Ankle eversion exercises~* Ankle Plantarflexion exercises
Study NCT05241795 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ankle then Knee rehabilitation protocol
Description: Patients will start ankle exercises program that includes:~* Standing calf raises~* Foot lift~* Ankle eversion exercises~* Ankle Plantarflexion exercises~Then, Patients will start with knee exercise program that includes~* Partial Squats: The exercise will be performed as 3 sets of 10 repetitions each day.~* Toe Raises: The exercise will be performed as 3 sets of 10 repetitions each day.~* Stationary bike will be used (10-15 minutes /day) when the patients can bend their knees at least 100 degrees, as cycling is considered as an excellent conditioning and building exercise for the quadriceps muscles. As the patient's ability to pedal the bike with the operative leg improved, the therapist will increase the resistance.~* Hamstring exercises: After 6 weeks, the hamstring muscles will be exercised by the patient pulling the heel back producing a hamstring contraction.
Study NCT05120440 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breakfast omission
Description: Breakfast omission will consist of not eating breakfast on the morning of afternoon resistance training performance assessment.