AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06074406 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyperfine
Description: Enrolled subjects will undergo a Hyperfine MRI exam, which is a portable, low-field MRI, at various timepoints during their clinical course on ECMO
Study NCT06457217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic resonance spectroscopic imaging
Description: High-resolution 3D metabolic imaging was performed using the SPICE 1H-MRSI sequence.
Study NCT05250934 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic rehabilitation
Description: The upper limb rehabilitation will be carried out with the planar rehabilitation robot Icone (a CE Class IIA medical device manufactured by Heaxel). The proposed exercises require the patient to move a cursor on the screen using the end-effector of the robot to reach specific points (planar reaching exercises). When the patient is able to perform these exercises independently, the robot assists the movement by minimizing the interaction force applied to the hand and limiting itself to acquiring the kinematic and dynamic parameters of the exercise, which are useful in determining the state of motor skills. Icone assist the subject by applying a force to his hand that helps him complete the task in the phases where the patient plans the movement correctly but is unable to complete it. As a result, the system will enable you to perform planar elbow and shoulder movements in active, passive, or active-assisted modes, with visual and acoustic feedback.
Study NCT06397625 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Percutaneous electrical neurostimulation (Placebo)
Description: Group I (Control), will be operated with the same procedure but without electric current, and using placebo needles of the same size (Streitberger Placebo-Needle ® , Asiamed, Pullach, Germany)
Study NCT06397625 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Percutaneous electrical neurostimulation
Description: The Group II and III electrostimulation procedure is called peripheral nerve stimulation and is known as an echo-guided peripheral nerve stimulation technique using a blunt, dry needle (active electrode). The intervention will be performed on the pudendal nerve, in an area where there is no risk of perforating any vascular-nerve bundle. The invasive technique will be performed by a physiotherapist expert in musculoskeletal and peripheral nervous system ultrasound and specialized in invasive techniques, with two years of experience in the sector. The needle will be introduced through the anterior (perineum).
Study NCT06497088 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nasotrak System
Description: Device: The Nasotrak System~The Nasotrak Medical System is intended to aid, in conjunction with institutional protocols, qualified operators in the placement of the Nasotrak's 12 Fr feeding tube into the stomach of patients requiring enteral feeding after insertion and before every feed. The Nasotrak nasogastric tube(NGT) is designed for use with Nasotrak's handheld device (HHD) which is able to detect the tip of the NGT via piezoelectric sensor, which converts ultrasound waves to electronic signals, thus assisting to track its location as an indicator of placement in the stomach. Nasotrak's NGT is intended only to be used with Nasotrak's HHD.~The Nasotrak NGT is intended for the administration of nutrition, fluids and medications by the nasoenteric route for patients who have an intact gastrointestinal tract but are physically unable to manage nutritional intake through normal mastication and deglutition.
Study NCT05811013 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial static magnetic field stimulation (tSMS)
Description: Patients will be randomly assigned to either real or sham tSMS. Real or sham tSMS will be performed daily without any interruption during each session of 60 min. Each patient will be instructed to self-administer tSMS, two sessions per day (AM and PM, 6-10 hours apart), sequentially for 60 minutes each, for 6 +6 months. Patients will choose whether to undergo stimulation at home or in the hospital on an outpatient setting. Real tSMS will be delivered with two cylindrical neodymium magnets (grade N45) of 45 mm diameter and 30 mm of thickness, with a weight of 360 g (MAG45r; Neurek SL, Toledo, Spain), applied with south polarity, each pointing toward the motor cortex. To discharge the weight of the helmet from the head during the sessions, patients will be instructed to rest the back of head and helmet on an inclined surface in a comfortable position. They will be also instructed to rest, minimizing movement, and not to watch audiovisuals during the stimulation sessions.
Study NCT05811013 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Transcranial static magnetic field stimulation (tSMS)
Description: Real or sham tSMS will be performed daily without any interruption during each session of 60 min. Each patient will be instructed to self-administer tSMS, two sessions per day (AM and PM, 6-10 hours apart), sequentially for 60 minutes each, for 6 +6 months. Sham tSMS will be delivered with non-magnetic metal cylinders, with the same size, weight and appearance of the magnets (MAG45s; Neurek SL, Toledo, Spain).
Study NCT06550141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emapalumab
Description: An interferon gamma (IFNγ) blocking antibody
Study NCT06550141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Alkylating agent
Study NCT06550141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine Phosphate
Description: Purine antagonist antimetabolite
Study NCT06550141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Axicabtagene Ciloleucel
Description: Autologous treatment
Study NCT05807633 — intervention group
Intervention type: DEVICE
Intervention: Novosyn®
Description: Novosyn® for uterus closure in patients undergoing cesarian section
Study NCT05796518 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PREVENT Cardiovascular Health Assessment Tool
Description: Participants will access a heart health information visualization tool online using a personal device or a study tablet computer using their e-mail address to log-in. Investigators will review participant lab results specifically related to their cardiovascular health (e.g. blood pressure, cholesterol) in order to personalize the heart health tool for participants. A brief survey before and after use of the tool will also be completed by participants.
Study NCT05796518 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey
Description: A brief survey before and after use of the tool will also be completed by participants.
Study NCT05796518 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview Regarding Heart Health
Description: Participants will be asked questions related to their heart health.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Neuromuscular ultrasound
Description: Ultrasound will be performed with the Affiniti 70 (Philips Medical Instruments, Bothell, WA). all patients following standardized methods of our hospital. All the patient would be checked the skin surface temperature before the ultrasound examination. The image would be exported from the echo machine as DICOM format.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Muscle MRI
Description: Muscle MRI will be performed on a 3-T MR machine (Trio; Siemens, Erlangen, Germany). Each subject will lie in a supine position comfortably, supplied with ear plugs. A high resolution T1 weighted scan and Short-T1 Inversion Recovery series (STIR) of the four limbs muscle were obtained in axial and coronal plane. MR spectroscopy in interested muscle was also sampled to evaluate the composition of fat, water, lactate, and other studied molecules.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Nerve conduction studies and autonomic function tests
Description: Nerve conduction study will be performed with a Nicolet Viking IV Electromyographer (Madison, WI) in all patients following standardized methods recommended by the Consensus Development Conference on Standardized Measures in Diabetic Neuropathy. Studied nerves include sural, peroneal, tibial, median and ulnar (motor and sensory) nerves.Autonomic functions will be assessed by the SSR and RRIV with established protocol by using Nicolet Viking IV Electromyographer (Madison, WI).
Study NCT06310239 — intervention group
Intervention type: OTHER
Intervention: Collection of biologic samples and data
Description: * collection of skin flora samples via swabs~* data collection regarding subject's medications See Detailed Description in Study Description section above for more details
Study NCT06104540 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental I liquid vaseline groups
Description: Patients in the liquid vaseline group will apply liquid vaseline twice a day for 3 months. Depending on the size of the burn area, 5-10 ml of liquid petroleum jelly will be applied to the burn area by massaging for 5 minutes twice a day, and each application will be recorded in the application follow-up form. Patients will be visited on the 15th day, first month, second month, and third month after the application begins.
Study NCT06104540 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental II extra virgin olive oil groups
Description: Patients in the extra virgin olive oil group will apply extra virgin olive oil twice a day for 3 months. Depending on the size of the burn area, 5-10 ml of liquid petroleum jelly will be applied to the burn area by massaging for 5 minutes twice a day, and each application will be recorded in the application follow-up form. Patients will be visited on the 15th day, first month, second month, and third month after the application begins.
Study NCT06104540 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Croup
Description: No intervention will be made other than the recommendations of the institution's physicians and nurses.
Study NCT05473884 — intervention group
Intervention type: DEVICE
Intervention: lesion preparation devices
Description: successful recanalization of femoropopliteal artery occlusion and then followed by lesion preparation devices and plain old balloon angioplasty
Study NCT05473884 — intervention group
Intervention type: DEVICE
Intervention: conventional balloon
Description: Lumen gain is achieved by plain old balloon angioplasty under working inflation pressure.
Study NCT04648709 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ELISPOT
Description: measure of immune response by ELISPOT
Study NCT06726889 — intervention group
Intervention type: BEHAVIORAL
Intervention: Feedback
Description: Feedback message will be delivered by physician to patients, through WhatsApp, after medication diary revision
Study NCT04648709 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: QUANTIFERON
Description: measure of immune response by QUANTIFERON
Study NCT05220800 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iron(III)isomaltoside
Description: Weight-dependent dosage of iron(III)isomaltoside. See group descriptions
Study NCT05220800 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Isoton saline infusion
Study NCT06645132 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: exercise intervention
Description: Exercise intervention leveraging wearable devices and a custom smartphone application to cue exercise as a reminder during idle time during an inpatient hospital stay, post allogenic bone marrow transplant.
Study NCT05506644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HRV-Biofeedback/Mind-Body Therapy
Description: A 7-week protocol using real-time feedback on heart rate variability
Study NCT05877404 — intervention group
Intervention type: OTHER
Intervention: Surveys
Description: Survey on practice patterns surrounding tumor genetic testing in endometrial cancer.
Study NCT05557019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Booster Balloon Catheter
Description: The Booster balloon therapy (i.e. partial occlusion of the CS lumen with a subsequent backward pressure elevation without obstructing the CS blood flow) will start immediately after a successful PCI of the culprit coronary lesion in the LAD, with TIMI-II flow restoration. The Booster balloon therapy will then be continued for up to 90 min, but not less than 60 min.
Study NCT05969561 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ultrasound-guided femoral nerve block
Description: The local analgesia is injected and infiltrated around the femoral nerve under ultrasound guidance.
Study NCT05969561 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Intravenous or intramuscular pain medication
Description: Intravenous or intramuscular pain medication is given for patients with hip fracture.
Study NCT04639206 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HOBSCOTCH
Description: HOBSCOTCH (Home Based Self-management and Cognitive Training Changes lives) is a home-based self-management program to treat cognitive symptoms and improve quality of life while minimizing the barriers of access to care. The program is based on Problem Solving Therapy (PST) and teaches problem solving strategies and compensatory mechanisms to help manage cognitive dysfunction and enhance quality of life. The HOBSCOTCH intervention consists of 8 weekly sessions conducted in-person, over the telephone, or via video-conferencing. A smart phone application will be used to collect data on seizure frequency, medication adherence, and patient engagement.
Study NCT05838560 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dasatinib + quercetin
Description: dasatinib 100mg / quercetin 1250mg The intervention will involve the participant taking both dasatinib and quercetin combined.
Study NCT06391203 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Long-term Drainage
Description: After drilling or puncture, the drainage catheter is indwelling continuously and keeps to drainage for 7 days. Keep incision sterility, record the daily fluid drainage flow, and perform biochemical and bacterial culture identification tests for CSF regularly. Removing drainage catheter when the allocated time is reached. If there is still unabsorbed effusion after the allocated time is reached, the catheter placement time is extended and the relevant information is recorded.
Study NCT06391203 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Short-term Drainage
Description: After drilling or puncture, the drainage catheter is indwelling continuously and keeps to drainage for 2 days. Keep incision sterility, record the daily fluid drainage flow, and perform biochemical and bacterial culture identification tests for CSF regularly. Removing drainage catheter when the allocated time is reached. If there is still unabsorbed effusion after the allocated time is reached, the catheter placement time is extended and the relevant information is recorded.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Quantitative sensory test
Description: Quantative sensory test will be performed with a Thermal Sensory Analyzer and Vibratory Sensory Analyzer (Medoc Advanced Medical System, Minneapolis, MN). The procedure is the same as previously described 25. Briefly, the machine delivers to the patient a stimulus of constant intensity which is pre-set by the algorithm. By adjusting the intensity of stimulus (increase or decrease the intensity by a fixed ratio) according to the response of the subject (i.e. whether the subject perceives the stimulus or not), sensory thresholds of the warm, cold and vibratory modalities will be measured.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Skin biopsy
Description: A skin specimen of 3 mm in diameter will be taken with a biopsy punch from the lateral side of the distal leg under 2% lidocaine local anaesthesia 26. No suturing is required, and the wounds are covered with a piece of gauze. Wound healing takes 7\~10 days, similar to a typical abrasion wound. Informed consent will be obtained from each patient before the skin biopsy. The intraepidermal nerve fiber density and sweat gland nerve innervation will be examined.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Muscle and nerve biopsy
Description: Two muscle specimens with 5 x 5 x 5 mm were collected in an open muscle biopsy or needle biopsy at studied muscles under 2% lidocaine local anaesthesia. The wound was about 2-3 cm long, and suture was required. Would healing usually takes 10-14 days. First specimen was undergoing snap freezing fixation in a longitudinal axis perpendicular to the cork with the liquid nitrogen and isopentane. The second specimen was divided into two equiponderous tissues, and one was freezed in liquid nitrogen for DNA and protein analysis. The another one was treated with RNAlater solution in 4°C overnight for RNA analysis. Sural nerve biopsies or superficial peroneal nerve were obtained from a standard site posterior to the lateral malleolus under local anesthesia. The nerves were then fixed in 5% glutaraldehyde in 0.1 M phosphate buffer (PB) at 4 °C overnight. All samples were stored in the -80°C refrigerator for further analysis.
Study NCT05952492 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stress Management Skills Training
Description: Participants will attend group sessions with a trained facilitator held over videoconference. Sessions will each last 2 hours and be held once weekly for 10 weeks. Sessions will include stress management skills training and health education content.
Study NCT06410287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ArtSpective
Description: ArtSpective is an interactive, educational program that uses art and museum-based pedagogy. The intervention is delivered asynchronously using a web-based platform. Participants engage with artwork, watch short educational videos, and read short clinical vignettes. After completing the program, participants receive a certificate of completion.
Study NCT06410287 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: ArtSpective
Description: ArtSpective is an interactive, educational program that uses art and museum-based pedagogy. The intervention is delivered asynchronously using a web-based platform. Participants engage with artwork, watch short educational videos, and read short clinical vignettes. After completing the program, participants receive a certificate of completion.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Genomics, transcriptome, and proteomics
Description: The DNA, RNA, and protein of the tissues (blood, muscle, nerve and skin) were retrieved and stored in the -80°C refrigerator. The next generation sequencing (whole exon sequencing or whole genome sequencing) and RNA-seq would be performed by NGS \& Microarray Core lab in National Taiwan University or another professional team. The protein analysis would be performed by the Proteomics \& Protein Function Core Lab in National Taiwan University.
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Laboratory of blood chemical substances, metals and endocrine profiles
Description: The methods of the measurement will follow the standards set by Department of Laboratory Medicine of National Taiwan University Hospital.
Study NCT06321757 — intervention group
Intervention type: DEVICE
Intervention: Percutaneous Coronary Intervention with DCB and DAPT
Description: * Patients with PCI (DCB) + standard DAPT standard dual antiplatelet therapy (DAPT)~* Patients with PCI (DCB) + short DAPT
Study NCT05048862 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Contact heat evoked potentials
Description: A contact heat evoked potential stimulator (Medoc, Ramat Yishai, Israel) will be used for delivering heat stimulation. Stimuli will be delivered repeatedly to the same stimulation site and the inter-stimulus interval will be randomly set to around 18\~22 s. CHEP will be recorded using a Nicolet Bravo evoked potential system (Nicolet Biomedical, Madison, WI). The recording electrode was placed at the Cz and P3 of international 10-20 system. The impendence of all recording electrodes was kept below 3 kΩ. The evoked potentials were filtered with a bandpass filter at 0.1\~30 Hz. Recording was triggered by the onset of each stimulus, and the sweep time was 1500 ms.
Study NCT04685590 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dasatinib + Quercetin
Description: D+Q will be administered once daily (1st dose of each cycle will be given, supervised, at the clinic visit; the 2nd dose will be taken at home) for 2 consecutive days followed by a 13-day (+/- 2 day) no-drug period for 12 consecutive weeks for 6 rounds of administration.
Study NCT04685590 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Capsules
Description: Matching placebo capsules following the same administration protocol as the experimental treatment - administered once daily (1st dose of each cycle will be given, supervised, at the clinic visit; the 2nd dose will be taken at home) for 2 consecutive days followed by a 13-day (+/- 2 day) no-drug period for 12 consecutive weeks for 6 rounds of administration.
Study NCT05809622 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Elbow focused rehabilitation
Description: * Patient education~* Activity modification~* 2 days/week, 8 weeks in total~* Exercises for the wrist extensor tendon, especially the extensor carpi radialis brevis (EKRB) (stretching + strengthening)
Study NCT05809622 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Scapular and rotator cuff muscles strengthening
Description: * Patient education~* Activity modification~* 2 days/week, 8 weeks in total~* Exercises for the wrist extensor tendon, especially the extensor carpi radialis brevis (EKRB) (stretching + strengthening)~* Scapular stabilizer muscle + rotator cuff (RM) strengthening
Study NCT04218708 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine patch and gum
Description: Nicotine patch and gum will be given to subjects in the Nicotine replacement therapy cohort every visit after providing exhaled CO/Saliva cotinine test.
Study NCT04218708 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Minnesota Nicotine Withdrawal Scale (MNWS)
Description: The MNWS assesses symptoms associated with nicotine withdrawal (i.e., craving, irritability, anxiety, difficulty concentrating, restlessness, increased appetite or weight gain, depression, and insomnia).