AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05838924 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PHYSICAL ACTIVITY + VIRTUAL REALITY
Description: The VR therapeutic exercise program will be implemented for 6 weeks at a frequency of 2 sessions per week with the aim of improving pain and disability, kinesiophobia, range of motion (ROM), catastrophizing, quality of life, and physical fitness. This group will perform the 8 VR exercises of Back School by manipulating visual proprioceptive information during all lumbar movements. They will be performed in 2 sets whose intensity and repetitions will be configured and individualized by a self-reported rating of perceived exertion (RPE) through the Borg 6-20 scale. The appropriate training intensity is established with an RPE score between 13 and 17; for this reason, the first 2 weeks will work at an RPE of 14, the 3rd and 4th weeks at an RPE of 15; and finally, the last 2 weeks will work at an RPE of 16. The first 3 weeks will work without additional load, and the last 3 weeks will work with weights, increasing their weekly load individually.
Study NCT05838924 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PHYSICAL ACTIVITY
Description: The 8 therapeutic exercise program will be implemented for 6 weeks at a frequency of 2 sessions per week with the aim of improving pain and disability, kinesiophobia, range of motion (ROM), catastrophizing, quality of life, and physical fitness. This group will perform the 8 exercises of Back School without VR. They will be performed in 2 sets whose intensity and repetitions will be configured and individualized by a self-reported rating of perceived exertion (RPE) through the Borg 6-20 scale. The appropriate training intensity is established with an RPE score between 13 and 17; for this reason, the first 2 weeks will work at an RPE of 14, the 3rd and 4th weeks at an RPE of 15; and finally, the last 2 weeks will work at an RPE of 16. The first 3 weeks will work without additional load, and the last 3 weeks will work with weights, increasing their weekly load individually.
Study NCT05363657 — intervention group
Intervention type: PROCEDURE
Intervention: Partial Nephrectomy (PN)
Description: Conservative removal of kidney tumor. The procedure can be performed either with an open or laparoscopic or robotic approach.
Study NCT05363657 — intervention group
Intervention type: PROCEDURE
Intervention: Radical Nephrectomy (RN)
Description: Surgical removal of the affected kidney. Adrenal removal can be performed according to surgeon choice and clinical characteristics of the renal tumor. The procedure can be performed either with an open or laparoscopic or robotic approach.
Study NCT05363657 — intervention group
Intervention type: PROCEDURE
Intervention: Ablation therapy (AT)
Description: The procedure of tumor ablation performed with radiofrequency or cryoablation. The procedure can be performed either with a laparoscopic approach or percutaneous access.
Study NCT05363657 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Active Surveillance (AS)
Description: Active surveillance is defined as the initial management including the monitoring of renal tumor size by serial imaging with delayed treatment in case of progression.
Study NCT04402658 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inhaled salbutamol
Description: Participants will inhale 800 μg salbutamol (or placebo) using a standard metered dose inhaler used for asthma treatment, and a standard spacer device will be used to allow optimal delivery of the drug to the lung. The inhaler delivers 100 μg of salbutamol with each actuation (i.e., 8 puffs/actuations gives 800 μg) with inhalation time being approximately \~2 min (10 breaths) and the manufacturer's user instructions will be followed. Although complete uptake of salbutamol cannot be concluded as any salbutamol left in the spacer, mouth or remaining in the lung will be not measured. This dose of Salbutamol is chosen because it is the highest dose permitted by the World Anti Doping Agency (WADA).
Study NCT05737433 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-rencofilstat 225mg
Description: radio-labelled 225mg oral dose of rencofilstat
Study NCT06668532 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Digital toolkit
Description: Access to the Flourish app and instruction to use at least twice a week for 6 weeks.
Study NCT05967182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given by IV (vein)
Study NCT05967182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Given by IV (vein)
Study NCT05967182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Given by IV (vein)
Study NCT06668532 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: National mental health resources
Description: Access to national mental health resources from Mental Health America, which can be found here: https://mhanational.org/ten-tools. Participants will receive one resource each week for 6 weeks and each time, will be asked to reflect on how the information can be applied to their own lives.
Study NCT05341323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine.
Description: Peritonsillar infiltration of ketamine
Study NCT05341323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: peritonsillar infiltration of Bupivacaine
Study NCT06495541 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Pyrotinib
Description: Administration method: Pyrrolitinib standard dose: 400 mg once a day, oral administration within 30 minutes after breakfast, continuous administration for 21 days per cycle. The dosage can be determined by the doctor according to the actual situation Make adjustments. Other medications: The doctor selects the medication plan based on the actual situation.
Study NCT05108207 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prevention software
Description: The software is installed on an Alcatel OneTouch Pixi-3 10 tablet and is delivered every day to each patient between 9:00 am and 8:00 pm, with nighttime pickup (8:00 pm to 09:00 am), so the patient can rest and to charge the device. The first day, a previously trained health professional delivers the tablet and trains the older adults in its use, taking 10 to 15 minutes. The day after the tablet is delivered, the same person goes to the patient's room to check if he or she has any doubts or problems with its use. Both groups are advised to use the tablet 3 times a day, at least 10 minutes each time.
Study NCT05108207 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: All patients will have a tablet without the software PREVEDEL between 09:00-19:00 hrs.
Study NCT05108207 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Implement a program of non-pharmacological interventions to prevent delirium
Description: Three months before the start of the clinical trial, an intervention is carried out in the Internal Medicine, Geriatrics and Intermediate Care Unit services of the 4 participating centers in order to establish a homogeneous plan of nPPD and assess adherence. The implementation methodology in the first stage will be according to the Consolidated Framework for Advancing Implementation Science (CFIR) model, used in a local pilot study.
Study NCT05108207 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Implement a program of non-pharmacological interventions to prevent delirium
Description: Three months before the start of the clinical trial, an intervention is carried out in the Internal Medicine, Geriatrics and Intermediate Care Unit services of the 4 participating centers in order to establish a homogeneous plan of nPPD and assess adherence. The implementation methodology in the first stage will be according to the Consolidated Framework for Advancing Implementation Science (CFIR) model, used in a local pilot study.
Study NCT06432660 — intervention group
Intervention type: OTHER
Intervention: Data collection
Description: Information about radiation therapy via eye plaque brachytherapy and follow up
Study NCT05774548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-depth interviews (IDI)
Description: In-depth interviews (IDI) 20 MSM,20 TGW, current, previous PrEP users will assess which attributes are relevant each population. Posters will be used to recruit for IDIs. Self-reported HIV-negative who either report interest in current or past PrEP use will be eligible to participate in IDI. IDI will be conducted by a study by in-person, on-line interviews.
Study NCT05774548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Focus group discussion (FGD)
Description: Focus group discussion (FGD) will discuss a interested information from IDIs. IDIs will be informed, invited to a FGD. FGD recruit 6-10 IDI. 10 random number will be generated using statistical if more 10 individuals show interest in participating in a FGD. If there are less than 6 accepted participants for a FGD, the backup list or new participant will be invited. Study will perform FGD by in-person, on-line conference. Data obtained during a process will be used to create a list of attributes for each population, their levels to include in the choice tasks, ensuring that a choices are plausible, exchangeable.
Study NCT06643676 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Targeted Endodontic Microsurgery Using 3d Printed surgical guide using the patient's CBCT data
Description: Patients with apical periodontitis with intact cortex in madibular molars receiving Targeted Endodontic surgery or Guided Endodontic Microsurgery with surgical guide fabricated using the cbct data following failure of non surgical root canal treatment
Study NCT06643676 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Endodontic Microsurgery with a free hand procedure using bur and CBCT analysis
Description: A conventional endodontic microsurgery using arbitrary localisation technique using the cbct data and performing the surgery with a carbide bur.
Study NCT06161012 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senofilcon A contact lenses (TEST)
Description: Rotationally stabilized astigmatic soft contact lenses in senofilcon A containing a chromophore to filter High-Energy Visible Light (HEVL)
Study NCT06161012 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Delefilcon A contact lenses (CONTROL)
Description: DAILIES TOTAL1® for Astigmatism Contact Lenses (DT1fA)
Study NCT05970120 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NUVISION NAV Ultrasound Catheter
Description: Participants will be scheduled to have a clinically-indicated ablation procedure using NUVISION NAV ultrasound catheter for management of atrial procedure.
Study NCT05733975 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Decision Making Guide
Description: The tool will be used by parent(s) to help guide them in discussion with their infant's clinicians.
Study NCT05958940 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bright Light Therapy
Description: In this study, Bright Light Therapy (BLT) will be administered according to Dutch depression guidelines, using Innolux LED light lamp (3800K, 10,000 lux). BLT will be given for one work week (Mon-Fri), 7:30-10:30 AM, 30 mins/session. Patients can have breakfast, read, or use devices. Treatment effectiveness will be evaluated using Self-Rated Quick Inventory of Depressive Symptoms (QIDS-SR). If remission is achieved (QIDS-SR \< 6), no additional treatment is given. If response is insufficient (QIDS-SR ≥ 6), 5 more sessions will be added in the following week, with maximum two extensions (1-3 weeks total).
Study NCT05958940 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bright Light Therapy
Description: In this study, Bright Light Therapy (BLT) will be administered according to Dutch depression guidelines, using Innolux LED light lamp (3800K, 10,000 lux). BLT will be given for one work week (Mon-Fri), 7:30-10:30 AM, 30 mins/session. Patients can have breakfast, read, or use devices. Treatment effectiveness will be evaluated using Self-Rated Quick Inventory of Depressive Symptoms (QIDS-SR). If remission is achieved (QIDS-SR \< 6), no additional treatment is given. If response is insufficient (QIDS-SR ≥ 6), 5 more sessions will be added in the following week, with maximum two extensions (1-3 weeks total).
Study NCT05958940 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blue Light Blocking Glasses
Description: Plastic, orange-coloured glasses that primarily block blue light. To be worn in the evening.
Study NCT05522075 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Training
Description: Subjects will be asked to perform exercise training (high-intensity interval training) under supervision, 3 times per week for 8 weeks. Each training session will last 40 minutes and will consist of 10-minute warm up at 70% of maximal heart rate (HRmax), four 4-minute intervals at 90% of HRmax with 3-min active recovery at 70% of HRmax and 5-minute cool down at 70% of HRmax.
Study NCT05522075 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Abstinence Intervention
Description: Subjects will be asked to abstain from alcohol for 8 weeks. Education materials and bi-weekly consultations will be provided.
Study NCT05522075 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Alcohol Abstinence Intervention
Description: Subjects will be asked to abstain from alcohol for 8 weeks. Education materials and bi-weekly consultations will be provided.
Study NCT04619420 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-63733657
Description: JNJ-63733657 low or high dose will be administered by IV infusion.
Study NCT04619420 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo matching to JNJ-63733657 will be administered by IV infusion.
Study NCT05563792 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Options for Pain Management using Non-medication Strategies
Description: The purpose of this study is to help Veterans learn about different ways they can manage chronic pain that do not involve medications. Veterans will work with a coach to explore their values and goals and how different non-medication approaches may fit into these values and goals.
Study NCT05793541 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phone call
Description: A phone call from a trained study clinician that uses a standardized phone script to (a) conduct a risk assessment and (b) recommend that the participant use their safety plan (any and all included components), which will be reviewed and revised as-needed during the call. This intervention occurs at High Risk only.
Study NCT05793541 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text messaging
Description: A text message conversation initiated by a trained study clinician that uses a standardized text messaging script to (a) conduct a risk assessment and (b) recommend that the participant use their safety plan (any and all included components), which will be reviewed and revised as-needed during the text messaging interaction. This intervention occurs at High Risk only.
Study NCT05793541 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Automated interactive smartphone-based tool
Description: An automated interactive, smartphone-based tool that will (a) (at High Risk only) guide the participant through a risk assessment and (b) (at High and Medium/Low Risk) present recommendation to use and a review of the safety plan.
Study NCT05793541 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-interactive pop-up messages
Description: Automated non-interactive, static pop-up messages that recommend use of the safety plan or its components (Medium/Low Risk only).
Study NCT05885282 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: paraspinal vibration
Description: In addition to lumbar spinal stabilization exercises, LV will be applied to the cervical and lumbar paraspinal muscles. Spinal stabilization exercises will be as in the control group. The duration of a session will be 50 minutes, with spinal stabilization exercises 40 minutes and LV 10 minutes.LV will be applied before the exercises. LV will be applied to the cervical paraspinal muscles for a total of 5 minutes (2.5 minutes on the right side, 2.5 minutes on the left side) while the patients are in a sitting position. LV will be applied to the lumbar paraspinal muscles for a total of 5 minutes (2.5 minutes on the right side, 2.5 minutes on the left side) while the patients are lying in the prone position. LV application will be made with Vibrasens © device and vibration frequency 80 Hz amplitude 1 mm will be selected.
Study NCT05885282 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: gastrosoleus muscle complex vibration
Description: In addition to lumbar spinal stabilization exercises, LV will be applied to the gastrosoleus muscle complex. LV application will be applied sequentially, bilaterally, to the gastrosoleus complex. LV will be applied before the exercises. LV will be applied for a total of 10 minutes (5 minutes each on the right and left) while the patients are lying in the prone position. LV application will be made with Vibrasens © device and vibration frequency 80 Hz amplitude 1 mm will be selected.
Study NCT05885282 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Exercise
Description: Lumbar spinal stabilization exerciseswill be given. Lumbar spinal stabilization exercises; Diaphragmatic breathing, and contraction of the transversus abdominis and multifidus muscles will be taught in the supine position. Activation of these muscles will be studied in different positions (prone, crawling, sitting, and sitting on different surfaces). The focus will be on increasing kinesthetic awareness. It will be desirable to ensure and maintain the activation of these muscles during subsequent exercises. Exercises will be continued according to the patient's functional status and individual needs. Advancement of exercises; extremity movements on dynamic surfaces, narrowing of support surfaces, reciprocal movements, increasing the number of resistance and repetitions. The duration of a session will be 40 minutes.
Study NCT05477277 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MAsS
Description: Add MAsS to standard of care MRI scan
Study NCT06667661 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Shining Star mHealth App
Description: The Shining Star mHealth App Intervention is a 12-week mobile health program designed to improve adherence to the 24-Hour Movement Guidelines (physical activity, screen time, and sleep) among preschool-aged children (3-4 years old). The intervention delivers weekly behavior-related goals and educational lessons to parents through a mobile app, including concise messages (\&lt;500 characters) and links to additional resources. The app also includes gamification features, behavior trackers, and a \&#34;Kids Corner\&#34; for child-friendly content. Parents receive reminders and can engage with other participants through an optional chat forum.
Study NCT06667479 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
Description: Once thermoneutral procedures are complete, participants in the CI group will be seated in the cold tub and submerged into the water (10º C). The sternal notch of each participant will be used as the anatomical marker to mark submersion point. Participants will sit with both arms outstretched underwater with their backs not touching the sides of the tub. Participants with a shorter stature will be provided an underwater cushion to meet the submersion requirements. The 4-minute timer will begin once confirmation of the participants submersion level and posture is determined. Once completed, the participant will be instructed to slowly exit the tub and allowed to dry and change as necessary.
Study NCT06667479 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Shower (CS)
Description: Once thermoneutral procedures are complete, participants in the CS group will be instructed to enter the research shower area. Within the shower area, the walls of the shower will be numbered from 1 to 4, with 1 defined as facing the faucet, 2 defined as 90° to the right of side 1, 3 defined as 180° from the faucet, and 4 defined as 270° to the right or 90° C to the left from side 1. Participants will be instructed to turn 90° to the right cycling through sides 1 to 4 and then back to 1 every 15 seconds prompted by the researcher. This will allow the participant to complete four full rotations in the shower during the 4-minute intervention time. The shower faucet is modified and oriented in a way where it only produces cold water (10º C) when turned on. Once completed, the participant will be instructed to slowly exit the shower and is allowed to dry and change as necessary
Study NCT05845775 — intervention group
Intervention type: PROCEDURE
Intervention: Percutaneous dilatational tracheostomy
Description: The percutaneous dilatational tracheostomy procedure will be performed via fiberoptic bronchoscopy
Study NCT05845775 — intervention group
Intervention type: DEVICE
Intervention: Bronchoscopy
Description: Fiberoptic bronchoscopy
Study NCT05845775 — intervention group
Intervention type: DEVICE
Intervention: ultrasonography
Description: ultrasonography
Study NCT05845775 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoscopy application
Description: Fiberoptic bronchoscopy application
Study NCT05845775 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound examination
Description: Ultrasound examination
Study NCT06287996 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: footbath and actigraphy
Description: Receive warm water foot bath for 4 weeks, 1 hour before going to bed every night (7-9PM), temperature 42℃ for 20 minutes, water depth 10cm above the ankle joint and wearing an actigraphy for 4 weeks
Study NCT06287996 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: actigraphy
Description: Wearing an actigraphy for 4 weeks
Study NCT06287996 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: actigraphy
Description: Wearing an actigraphy for 4 weeks
Study NCT04903223 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin 10mg
Description: Rosuvastatin will be administered to all participants on Study Day #2
Study NCT04886427 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: Measure the experiences of the current care