AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05846737 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-BCMA CAR-T
Description: Autologous BCMA-directed CAR-T cells, infusion intravenously at a target dose of 2-4 x 10\^6 anti-BCMA CAR+T cells/kg.
Study NCT04772560 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Precision1 for Astigmatism
Description: Daily disposable soft toric contact lens
Study NCT04772560 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Precision1 Sphere
Description: Daily disposable soft spherical contact lens
Study NCT05968729 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: 0.25 m/s asymmetric session first
Description: Participants will first perform an asymmetric walking trial where the between-limb gait speed difference is 0.25 m/s on day one. On the second day, participants will perform an asymmetric walking trial where the between-limb gait speed difference is 0.50 m/s.
Study NCT05968729 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: 0.50 m/s asymmetric session first
Description: Participants will first perform an asymmetric walking trial where the between-limb gait speed difference is 0.50 m/s on day one. On the second day, participants will perform an asymmetric walking trial where the between-limb gait speed difference is 0.25 m/s.
Study NCT05205889 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile intervention on values and goals in patients with chronic pain.
Description: The protocol consists of 10 daily sessions, 10-20 Minutes each. After each session participants will complete daily measures. Participants will learn about values and a values based life. Further they will identify their own values and are encouraged to set a goal to pursue those values. Based on this, barriers to achieving goals are explained and a corresponding commitment will be made.
Study NCT04711226 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AT-1501
Description: AT-1501 IV infusion
Study NCT05675488 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ultrasound
Description: Thickness of flexor tendon and A1 pulley at MCP joint level
Study NCT06112886 — intervention group
Intervention type: OTHER
Intervention: There was no intervention in this study
Description: There was no intervention in this study
Study NCT05179590 — intervention group
Intervention type: OTHER
Intervention: Quality of Dream
Description: Patients frequently report having dreams during general anesthesia, and the dreams are often reported to be pleasant dreams.~However, factors associated with the quality of dreams during general anesthesia have not been clarifed. The aim of this study was to determine the relationships between the quality of dreams during general anesthesia and perioperative factors.~This prospective observational study included patients scheduled for elective surgery under general anesthesia.
Study NCT05785442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anakinra Prefilled Syringe
Description: Anakinra 100 mg administration subcutaneously once daily for 10 days (at least 4 days)
Study NCT05785442 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.67 ml N/S 0.9% w/v administration subcutaneously once daily for 10 days (at least 4 days)
Study NCT05216354 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib will be administered as a single dose on the morning of Day 1 under fasting conditions
Study NCT06208371 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical resection and/or ablation therapy and/or SBRT
Description: Participants may receive surgical resection and/or ablation therapy and/or stereotactic body radiotherapy
Study NCT06208371 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Palliative Chemotherapy
Description: Participants in this group may continue the original systemic chemotherapy regimen. Patients with tumor control after 10-12 cycles can either transition to maintenance treatment or temporarily suspend treatment until disease progression, at which point they switch to a second-line treatment regimen.The selection of second-line and subsequent treatment regimens follows CSCO guidelines and clinical practices.
Study NCT05438472 — intervention group
Intervention type: OTHER
Intervention: data collection in healthcare professionals with COVID-19 mRNA vaccine booster
Description: Day 3 (48 - 96h) post COVID-19 mRNA booster: data collection on symptoms (chest pain, dyspnea, myalgia, fever, chills); blood sample for cardiomyocyte injury (hs-cTnT, hs-cTnI). If elevated hs-cTnT concentration, participant has to avoid strenuous exercise. Work-up on Day 4: clinical evaluation, ECG, 2. blood sampling for hs-cTnT. If hs-cTnT > 100 ng/l, cardiac magnetic resonance imaging is done for signs of cardiac inflammation. If hs-cTnT rises above upper limit but doesn't exceed 100 ng/l, clinical exam might be evaluated. In confirmed myocarditis, a clinical assessment (treatment, need for hospitalization, length of rhythm monitoring, rest) is evaluated by a cardiologist. Day 4: EDTA blood from all subjects with elevated troponin at day 3 post-vaccination is collected for pathomechanism of mRNA vaccine associated myocarditis. 1-month follow-up: questionnaire on predefined cardiac endpoints.
Study NCT05291715 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ozone generator device (Ozone DTA-APOZAa-enterprize CO9-Taiwan, R.0.C)
Description: Gaseous ozone ( O3-triatomic oxygen) activates the neuroprotective systems, improve the blood circulation, oxygen delivery, stimulate the immunocompetent cells and enhance the release of growth factors. Moreover, ozone therapy showed to increase the quality of life post-operatively to a free gingival graft harvesting and decrease post-operative pain sensation ( Tasdemir et al, 2016)
Study NCT05933850 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strong Families Programme Intervention
Description: This is a family skills programme providing an evidence-informed prevention to support caregivers to be better parents and strengthen positive age-specific and age-appropriate family functioning and interactions to help prevent drug use, violence and other negative social consequences in their children.
Study NCT05933850 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Strong Families Programme Intervention
Description: This is a family skills programme providing an evidence-informed prevention to support caregivers to be better parents and strengthen positive age-specific and age-appropriate family functioning and interactions to help prevent drug use, violence and other negative social consequences in their children.
Study NCT05274893 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYHX2011 and Abraxane®
Description: IV infusion, 260 mg/m\^2
Study NCT05868434 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Medial Patellofemoral Ligament Reconstruction (MPFLR) With Fascia Lata Allograft, Based on Isometry Assessment Combined With Elmslie-Trillat Tibial Tuberosity Osteotomy.
Description: Medial Patellofemoral Ligament Reconstruction (MPFLR) With Fascia Lata Allograft, Based on Isometry Assessment Combined With Elmslie-Trillat Tibial Tuberosity Osteotomy. Management of any accompanying patellofemoral lesions will be performed as well.
Study NCT05536596 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Orthognathic Surgery
Description: Prognathism/Retrognathism correction through surgical procedures
Study NCT05536596 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Orthognathic Surgery
Description: Prognathism/Retrognathism correction through surgical procedures
Study NCT05536596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 10 MG Oral Tablet
Description: Group B will receive the pharmacology treatment with 10 mg Melatonin. One capsule orally at night for 60 days.
Study NCT05536596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxycobalamin
Description: Group C will receive the pharmacology treatment with 1 mg hydroxycobalamin (vitamin B12). One capsule daily for 60 days.
Study NCT05536596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Centrum
Description: Groups A will receive the pharmacology treatment with 1.5 mg uridine triphosphate, 2.5 mg cytidine monophosphate and 1 mg hydroxycobalamin (Citoneuron). One capsule orally three times a day for 60 days as suggested by the manufacturer for patients with trauma - compressive peripheral neural disorders.
Study NCT05838118 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Fecal Microbiota Transplantation
Description: Biologically active human fecal fluid (donor stool) is provided in fluid form.
Study NCT05838118 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard of Care for Chronic Kidney Disease
Description: Patients accepted oral drug or dialytic therapy like they used to be to treat CKD.
Study NCT04822506 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Routine perioperative management and PEA
Description: Routine perioperative management： All patients were given perioperative fluid rehydration and nutritional support to correct acid-base imbalance, electrolyte disturbance, anti-infection, hemostasis and other symptomatic treatment； electroacupuncture protocol： Preoperation:RN 6 + RN 4 +ST30 + ST 36+ Hegu (bilateral),De qi, electroacupuncture, continuous wave, 5Hz, 30min before surgery at 19:00 PM Inoperatively: LI 4+ PC 6 + ST36 + GB 34 (bilateral) ,Deqi, electroacupuncture with density wave, 2/100Hz, 30 minutes before operation to the end of the operation Postoperative: LI 4 +SJ 6 + ST 6 + ST 37(Left);LI 4 +SJ 6 + ST 6 + ST 37(Right)(alternated on both sides per 12h) Deqi, electroacupuncture, continuous wave, 5Hz, 30min,19:00 on the left side and 07:00 on the next day after surgery,until to first flatus (FF)
Study NCT04822506 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Routine perioperative management and postEA
Description: Routine perioperative management： All patients were given perioperative fluid rehydration and nutritional support to correct acid-base imbalance, electrolyte disturbance, anti-infection, hemostasis and other symptomatic treatment； electroacupuncture protocol： Postoperative: LI 4 +SJ 6 + ST 6 + ST 37(Left);LI 4 +SJ 6 + ST 6 + ST 37(Right)(alternated on both sides per 12h) Deqi, electroacupuncture, continuous wave, 5Hz, 30min,19:00 on the left side and 07:00 on the next day after surgery,until to first flatus (FF)
Study NCT04812392 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous Glucose Monitoring System
Description: Subjects will wear a continuous glucose monitoring system for 3 days during the 3 day reduced physical activity phase.
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle energy technique of erector spinae muscle
Description: Therapist will develop cross hand position left hand on lower thoracic and right hand on sacrum. Patient will asked to lift shoulder out of couch to contract the lumber erector spinae and apply force twenty percent against therapist force and keep this position of muscle contraction 7 to 10 seconds then 5 second relax .~Then therapist will take new position of muscle restriction by slacking and will hold 30 second that position at the end of restriction then will finally end stretch with three repetition. Muscle energy technique of erector spinae muscle.
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle energy technique of quadratus lumborum muscle
Description: Therapist will take step over the patient off leg and squeezes gently with their thigh. Patient will abduct leg with 20 percent force against the resistance of therapists thigh for 7 to 10 second. the therapist gently and passively will move patient leg towards adduction by squatting down slowly. Therapist at same time with both hands cradling the iliac crest of pelvic for 30 second stretch and 3 repetition.
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stretching of erector spinae muscle
Description: The therapist standing on the side in a way to place his elbow placed on erector spine and apply stretching on the muscle belly in the direction of longitudinal or transverse plane( figure 1).Duration of stretch will be 15 seconds and four repetition.
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stretching of quadratus lumborum muscle
Description: Placing patient's legs to one side of the table and upper body also move to the same side in lateral flexion. This position generate a basic gentle stretch of the muscle. The therapist use elbow on tight/ flat part of muscle belly to stretch out the muscle(figure 2). Duration of stretch will be 15 seconds and four repetition
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Back strengthening exercises
Description: 1. Supine Abdominal Draw In~2. Supine Butt Lift with Arms at Side~3. Abdominal Draw In with Heel Slide~4. Abdominal Draw In with Knee to Chest~5. Abdominal Draw In with feet on the ball~6. Abdominal Draw In with feet on the ball- add movement
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Back strengthening exercises
Description: 1. Supine Abdominal Draw In~2. Supine Butt Lift with Arms at Side~3. Abdominal Draw In with Heel Slide~4. Abdominal Draw In with Knee to Chest~5. Abdominal Draw In with feet on the ball~6. Abdominal Draw In with feet on the ball- add movement
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thermotherapy
Description: Ten minute duration of hot pack given on low back for local superficial heat.
Study NCT05360121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thermotherapy
Description: Ten minute duration of hot pack given on low back for local superficial heat.
Study NCT05777356 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Urine collection and assessment of dietary intake by food frequency questionaire
Description: urinary iodine, creatinine and methylmalonic acid, iodine and vitamin B12 dietary intake from foods and supplements
Study NCT05674305 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Radiotherapy
Description: IMRT for primary and regional field
Study NCT05674305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: IMRT for primary and regional field
Study NCT05674305 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Cisplatin 80mg/m2, 21days/cycle, 2 cycles
Study NCT04743778 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Diabetes Self-Management Education and Support
Description: Diabetes self-management education and support delivered through Zoom for health.
Study NCT06434142 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: implant overdenture
Description: Following the two-stage surgical protocol, two dental implant fixtures with a length of 10 mm and a diameter of 3.7 mm were inserted at the canine area of the mandibular alveolar ridge.
Study NCT05494164 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nigella sativa nasal oil drops
Description: in addition to the standard treatment, the study group will receive one nasal drop of the prepared N. sativa nasal oil drops in each nostril twice daily which are equivalent to a daily dose of 100 milligram of a pure N. sativa oil for four weeks. N. sativa oil was prepared from N. sativa seeds and it was mixed in Sesame oil with a ratio of 1 to 1. The prepared drops will then be placed in dark containers with a specific dropper. Each participant will be instructed regarding the dose, proper position and steps, assisted by a flyer which will be developed by the researcher.
Study NCT05494164 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: standard treatment
Description: intranasal corticosteroids in addition to nasal irrigation with sea water; for patients with allergy the standard treatment is oral antihistamines with or without oral corticosteroids.
Study NCT05494164 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard treatment
Description: intranasal corticosteroids in addition to nasal irrigation with sea water; for patients with allergy the standard treatment is oral antihistamines with or without oral corticosteroids.
Study NCT06333119 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: modified rankin scale
Description: Modified Rankin Scale: The functional status of individuals with stroke is determined by this scale.~Modified Ashworth Scale: It allows determining the severity of spasticity. Tinetti Balance and Gait Scale: This scale helps determine the risk of falling by evaluating balance and gait.~Danish Prostatic Symptom Score: It allows to evaluate the storage and urinary functions of the bladder.
Study NCT05321277 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Walnuts
Description: Participants will consume 56 g of walnuts daily for 3 weeks. Participants will also follow a diet devoid of ellagitannin-rich, high fiber, and fermented foods.
Study NCT05321277 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: No-nut diet
Description: Participants will exclude all nuts and nut-derived products; high-fiber, fermented and ellagitannin-rich foods will also be excluded.
Study NCT06428292 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Virtual reality device branded ''Meta Quest 2''
Description: Combining different exercise equipment with a virtual reality device and using them in a virtual environment can be used to decide which one is more effective.
Study NCT05762068 — intervention group
Intervention type: OTHER
Intervention: Delphi procedure
Description: The study involves generating consensus statements by experts on airway management in critically ill patients on the definition and management of a physiologically difficult airway (PDA) using a Delphi process.
Study NCT05115071 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Childbirth preparation education
Description: Purpose: The aim of the birth preparation education is to eliminate the fears and concerns of pregnant women about birth and to prepare them for birth during the Covid-19 Pandemic process.~Education hours: The education will be completed in total two weeks and eight hours, consisting of two days and four hours each week.~Method: The education will be given online through the Microsoft Teams application. Each training day will consist of two lessons. Each lesson will last 45 minutes. There will be a 15-minute break between the two lessons. The first lesson will be conducted in the form of a question and answer session with a power-point presentation.In the second lesson, relaxation exercises will be applicated and evaluations will be taken at the end of the lesson.~The group that will receive the education: Healthy pregnant women between 24-34 weeks of gestation will be included in the training. Trainings will continue with closed groups.
Study NCT05214820 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Radiopharmaceutical 68Ga-PSMA
Description: Injection of 68Ga-PSMA followed by 3 PET/CT acquisitions
Study NCT06311097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fermented dairy
Description: Participants will consume 300g of yogurt daily for 4 weeks as an integral part of their habitual diet, substituting other food items.
Study NCT06311097 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Non-fermented dairy
Description: Participants will consume 300g of milk daily for 4 weeks as an integral part of their habitual diet, substituting other food items.
Study NCT05053958 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: superimposition of DICOM file from CBCT and STL file of Intraoral scanner
Description: These files will be imported in implant planning software,and virtual implant planning will be performed.
Study NCT05927649 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omaveloxolone
Description: Omaveloxolone capsules
Study NCT05927649 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxifloxacin
Description: Moxifloxacin capsules
Study NCT06172062 — intervention group
Intervention type: OTHER
Intervention: laparoscopic pancreaticoduodenectomy
Description: we recorded the surgical videos of laparoscopic pancreaticoduodenectomy, and labeled the information in the video to build and test the algorithms.
Study NCT06186193 — intervention group
Intervention type: BEHAVIORAL
Intervention: MyP
Description: see above: attention exercise based on phone app
Study NCT01453985 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Full-Thickness-Gastroplication
Study NCT05370937 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ARTROSCOPİC SURGERY WITH ELEVATOR SYSTEM
Description: TRANSTİBİAL PULL OUT REPAİR FOR MEDİAL MENİSCUS POSTERİOR ROOT TEARS
Study NCT05370937 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ARTROSCOPİC SURGERY WITHOUT ELEVATOR SYSTEM
Description: TRANSTİBİAL PULL OUT REPAİR FOR MEDİAL MENİSCUS POSTERİOR ROOT TEARS WITH ELEVATOR SYSTEM
Study NCT05801341 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lollipop
Description: An oral lollipop swab will be obtained by placing a flocked swab into the mouth and sucking on the swab for 20 seconds as one would suck on a lollipop
Study NCT06104436 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individualized music playlist
Description: Individualized music playlist composed of preferred music genres sequenced according to the ISO-Principle. It will be played at the state of agitation.
Study NCT06104436 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Preferred music
Description: Preferred music is composed of the genres selected by the participants, and to be played at random sequence.
Study NCT06104436 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual technique for calming agitated older adults with dementia
Study NCT06104436 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual technique for calming agitated older adults with dementia