AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06598488 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beetroot juice
Description: Beetroot juice will be consumed 2 times a day for 4 days before testing plus one shot on experimental testing day 1,5 hours before arrival.
Study NCT06598488 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Beetroot juice placebo
Description: Beetroot juice will be consumed 2 times a day for 4 days before testing plus one shot on experimental testing day 1,5 hours before arrival.
Study NCT05427422 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI recording
Description: MRI imaging was performed using a 3 Tesla Siemens Prisma system with a 64-channel head/neck coil (Siemens Medical Systems, Erlangen, Germany). The MRI protocols included as follows: (i) Magnetization-Prepared 2 Rapid Acquisition Gradient Echoes: TR/TE/ TI1/TI2 = 5000/2.98/700/2500 ms, voxel size = 1.0 × 1.0 × 1.0 mm3, FOV = 256 × 240 × 176 mm3; (ii)Gradient-echo EPI: TR 720 ms, TE 33.1 ms, flip angle 52 deg, FOV 208x180 mm, Matrix 104x90, Slice thickness 2.0 mm; 72 slices; 2.0 mm isotropic voxels, Multiband factor 8, Echo spacing 0.58 ms, BW 2290 Hz/Px; (iii) DSI : TR/TE = 3300/73 ms, FOV = 220 × 220 × 60 mm3, voxel size = 2 × 2 × 2 mm3, 128 diffusion direction, b-max = 3000 sec/mm2, AT = 7:22 min); (iv) T2-weighted fluid-attenuated inversion recovery: TR/TE = 9000/84 ms, FOV = 270 × 320 × 22 mm2, voxel size = 0.72 × 0.72 × 6.6 mm3.
Study NCT05427422 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EEG recording
Description: EEG was performed using a BrainAmp MR 32 amplifier (BrainProducts GmbH, München, Germany). The EEG protocols included as follows: (i) EEG-fMRI fusion: Sampling rate: 5000 Hz, low cut off-high cut off: DC-1000Hz;(2) EEG-fMRI fusion: Sampling rate: 1000 Hz, low cut off-high cut off: DC-1000Hz.~In (i) an ECG channel would be used to collect artifact of pulse and not used in (ii).
Study NCT06597162 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: education of patient safety
Description: For participants in the training group, data will be collected face to face in two stages: the pre-test phase and the post-training post-test phase.~A survey will be distributed to the control group simultaneously with the training group and will be collected as pre-test and post-test, but no training will be given to the control group. Only after the study ends will educational materials be shared with the control group.
Study NCT06597461 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial release
Description: Graston massage technique was used in the application. In the application, the participant was placed in a prone position and the feet were left slightly outside the massage table. The application was performed on the entire plantar surface between the calcaneal tuberosity and metatarsophalangeal joints in the form of multidirectional strokes at 30-60 degrees with the GT 4 graston tool. The total application took an average of 5 minutes for each foot. An average of 60-70 strokes were performed per minute and 10 seconds of rest was given every minute. The application was performed as a single session by an expert physiotherapist.
Study NCT06597461 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo myofascial release
Description: Graston massage technique was used in the application. In the application, the participant was placed in a prone position and the feet were left slightly outside the massage table. The application was performed on the entire plantar surface between the calcaneal tuberosity and metatarsophalangeal joints in the form of multidirectional strokes at 30-60 degrees with the GT 4 graston tool. The total application took an average of 5 minutes for each foot. An average of 60-70 strokes were performed per minute and 10 seconds of rest was given every minute. The application was performed as a single session by an expert physiotherapist. Since it was a placebo application, no pressure was applied to the tissues by the physiotherapist during the strokes.
Study NCT06596733 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vit-A-Vision
Description: Participants will apply Vit-A-Vision ointment on a daily basis, up to 3 times daily per eye, for at least 30 days.
Study NCT06591208 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: pulsed dye laser
Description: PDL (Cynosure - Chelmsford, MA-USA) wavelength 585 nm at a fluence 2.5-5 J/cm2, pulse duration of 0.5 ms and spot size 7 -10 mm
Study NCT06591208 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Carboxytherapy
Description: carboxytherapy (Carbo - Programmable automatic carbon dioxide therapy apparatus, MA-USA) that was automatically calibrated to adjust the flow rate, through regulation of infusion pressure and the dosage of CO2 in ml. the infusion velocity consequently was adjusted to a flow rate of 1 cc/. The injection performed slowly, subcutaneously, by tilting the needle at 15 degree using a sterile disposable insulin needle, with the depth adjusted at 2 mm. the gas volume per injection spot is 2ml with 1.5 cm spacing between each injection point. End point was skin distension with the gas giving the characteristic popcorn appearance.
Study NCT06586814 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Suture
Description: Wound Closure
Study NCT06586814 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Staple
Description: Wound Closure
Study NCT06600503 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RehabLung mobile application
Description: Participants in the intervention group will receive in-person pulmonary rehabilitation during their surgical admission and access to a mobile pulmonary rehabilitation application for self-training. This program begins one month before surgery and continues for seven weeks after surgery. The application is designed to encourage participants to engage in pulmonary rehabilitation exercises from preoperative preparation through postoperative care. It offers guided chest breathing exercises, using visual and movement instructions created and remotely prescribed by a physical therapist. Participants will receive daily breathing exercise prescriptions throughout the study period.
Study NCT06600503 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lung cancer postoperative standard care
Description: Participants in the usual care group will receive in-person pulmonary rehabilitation during surgical admission, pre-operative healthcare, and guidance on breathing exercises to practice before surgery. They will also receive post-operative breathing exercise prescriptions to follow at home.
Study NCT06600503 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Healthcare interactive Web Platform
Description: The healthcare interactive Web Platform provides patients with surgical information through animations. This includes an introduction to lung surgery, preparation procedures, answers to common patient questions, post-surgery wound care, and a brief guide to pulmonary rehabilitation.
Study NCT06600503 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Healthcare interactive Web Platform
Description: The healthcare interactive Web Platform provides patients with surgical information through animations. This includes an introduction to lung surgery, preparation procedures, answers to common patient questions, post-surgery wound care, and a brief guide to pulmonary rehabilitation.
Study NCT06590545 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KYV-101, an autologous fully-human anti-CD19 CAR T-cell immunotherapy
Description: A dosage of 1x10\^8 KYV-101 CAR+ T cells will be administered intravenously as a single infusion.
Study NCT06594211 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ACT-001 CAR-NK cell
Description: Subjects were distributed into three dosage groups, each receiving a single dose of CAR-NK cells at levels of 1×10\^8, 3×10\^8, and 9×10\^8 cells, respectively.
Study NCT06598215 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Duckett urethroplasty
Description: hybrid duckett urethroplasty vs modified duckett urethroplasty
Study NCT06587048 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: periapical surgery
Description: In piezo group, the periapical surgery will be performed using piezoelectric device.
Study NCT06587048 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: periapical surgery
Description: In conventional bur group, the periapical surgery will be performed using rotary burs.
Study NCT06603129 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: prognostic nutritional index
Description: Prognostic nutritional index is an inflammation-based scoring that measures the nutritional and immunological status of patients and has been used to determine prognosis and predict postoperative complications.
Study NCT06602609 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Remote Patient Monitoring Strategy
Description: Continuous remote monitoring with the SmartCardia device includes continuous heart rate and cardiac conduction rhythm tracking through a 7-lead ECG enhanced by machine learning. This system can detect cardiac rhythm disturbances, measure breathing and heart rate, and provide live-alert notifications. Daily 12-lead ECG will be collected from each patient for 7 days after discharge; patients are instructed to perform a daily 12-lead ECG on the SHL device, along with recording blood pressure and oxygen saturation levels. Each ECG is interpreted by the trial team, and a cardiologist\&#39;s interpretation is confirmed, and patients will undergo remote consultations with a cardiologist or research nurse each day if needed. During the initial 30 days of patient recruitment, if the individual exhibits potential cardiac symptoms, they can activate a remote consultation by performing an extra 12-lead ECG and recording blood pressure and oxygen saturation levels.
Study NCT06602609 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard Medical Therapy
Description: No intervention is required. Patients in this arm will fill out a self-reported anxiety report (SHAI form) and provide recent admission information
Study NCT06594640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitoxantrone Hydrochloride Liposome
Description: assigned dose according to the 3+3 dose-escalation design in part 1, RP2D in part 2, D2
Study NCT06594640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab (R)
Description: 375mg/m2, D2
Study NCT06594640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide (CTX)
Description: 750mg/m2, D2
Study NCT06594640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristin
Description: 1.2mg/m2, maximum 2mg， D2
Study NCT06594640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone
Description: 60mg/m2, D2-6
Study NCT06588231 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individual rehabilitation exercise training
Description: Under the guidance of a specialist, medium-and high-intensity interval training was conducted for 16 weeks, 3 times a week, 30-40 minutes each time, including the beginning of 5 minutes of warm-up and the last 5 minutes of cooling-off period, during which the exercise included 4 intervals, with the 85-95% pre intensity of HR reserve for 15-18 minutes, and then with the 50-70% pre intensity of HR reserve for 12-14 minutes, exercise for 3 minutes, and so on for 4 times. Warm-up and cooling-off periods can be done through stretching exercises, flexibility exercises (that is, neck, shoulders, upper back, buttocks and ankles) and low and medium intensity (50-70% heart rate reserve)
Study NCT06588231 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: optimal medical therapy ：aspirin, clopidogrel, statins.
Description: those in the control group were treated with routine antiplatelet drugs and lipid-lowering drugs after operation. Professional salesmen, according to the specific physical conditions of the patients, formulate corresponding recipes to ensure that the patients have a light diet, low salt, low fat and high nutritional value, and prohibit tobacco and alcohol.
Study NCT06588231 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: optimal medical therapy ：aspirin, clopidogrel, statins.
Description: those in the control group were treated with routine antiplatelet drugs and lipid-lowering drugs after operation. Professional salesmen, according to the specific physical conditions of the patients, formulate corresponding recipes to ensure that the patients have a light diet, low salt, low fat and high nutritional value, and prohibit tobacco and alcohol.
Study NCT06331299 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UGN-103
Description: UGN-103 consists of mitomycin and sterile hydrogel (a proprietary thermally responsive gel) that is used to reconstitute mitomycin before instillation. The reverse thermal properties of UGN-103 allow for local administration of mitomycin as a liquid under chilled conditions, with subsequent conversion to a semi-solid gel depot following instillation into the bladder.
Study NCT06263010 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Allopregnanolone
Description: Allopregnanolone is a neurosteroid ( 3α,5α-tetrahydroprogesterone, 3α-hydroxy-5α-pregnan-20-one) and by-product of the metabolism of the hormone progesterone.
Study NCT06263010 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Allopregnanolone
Description: Allopregnanolone is a neurosteroid ( 3α,5α-tetrahydroprogesterone, 3α-hydroxy-5α-pregnan-20-one) and by-product of the metabolism of the hormone progesterone.
Study NCT06599645 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CST+BFR+Tai Chi+Education
Description: 1. Core Stability Training: It includes core activation exercises (feed-forward control)(Libenson,2006). Each set will consist of 10 repetitions of this exercise with a 10-second hold. There will be a 30-second rest between repetitions and a 60-second rest after each set.~2. Tai Chi: The first 10 Tai Chi movements from the 24-simplified Tai Chi form. Three qualified teachers will lead the training sessions.~3. Blood Flow Restriction: The professional physical therapist puts on the cuff pneumatic tourniquet system(Kaastu Master) on the proximal end of the left lower limb of the subjects and gives a certain pressure through the Kaastu Master. The pressure needs to ensure that the venous return of the particapants is restricted to perfect ground, while the artery still has some blood flow.~4. Education: After enrollment, patients will receive face-to-face education sessions at baseline, 30-45 min each time. Guided education by the same experienced professional physiotherapist.
Study NCT06599645 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CST+BFR+Education
Description: 1. Core Stability Training: It includes core activation exercises (feed-forward control)(Libenson,2006). Each set will consist of 10 repetitions of this exercise with a 10-second hold. There will be a 30-second rest between repetitions and a 60-second rest after each set.~2. Blood Flow Restriction: The professional physical therapist puts on the cuff pneumatic tourniquet system(Kaastu Master) on the proximal end of the left lower limb of the subjects and gives a certain pressure through the Kaastu Master. The pressure needs to ensure that the venous return of the particapants is restricted to perfect ground, while the artery still has some blood flow.~3. Education: After enrollment, patients will receive face-to-face education sessions at baseline, 30-45 min each time. Guided education by the same experienced professional physiotherapist.
Study NCT06599645 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tai Chi +BFR+Education
Description: 1. Tai Chi: The first 10 Tai Chi movements from the 24-simplified Tai Chi form. Three qualified teachers will lead the training sessions.~2. Blood Flow Restriction: The professional physical therapist puts on the cuff pneumatic tourniquet system(Kaastu Master) on the proximal end of the left lower limb of the subjects and gives a certain pressure through the Kaastu Master. The pressure needs to ensure that the venous return of the particapants is restricted to perfect ground, while the artery still has some blood flow.~3. Education: After enrollment, patients will receive face-to-face education sessions at baseline, 30-45 min each time. Guided education by the same experienced professional physiotherapist.
Study NCT06599645 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: CST+Education
Description: 1. Core Stability Training: It includes core activation exercises (feed-forward control)(Libenson,2006). Each set will consist of 10 repetitions of this exercise with a 10-second hold. There will be a 30-second rest between repetitions and a 60-second rest after each set.~2. Education: After enrollment, patients will receive face-to-face education sessions at baseline, 30-45 min each time. Guided education by the same experienced professional physiotherapist.
Study NCT06595407 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood analysis for loss-of-Y chromosome
Description: Analysis for the percentage of circulating leukocytes with loss-of-y chromosome
Study NCT05383937 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Speech Therapy INTENS-DYS
Description: During the six research month, children included in the intensive arm will benefit of two daily hours speech therapy during two weeks. Those one will be carried out between the second and the fourth month.
Study NCT05383937 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Speech Therapy INTENS-DYS
Description: During the six research month, children included in the intensive arm will benefit of two daily hours speech therapy during two weeks. Those one will be carried out between the second and the fourth month.
Study NCT05191992 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CPR training with e-learning with a handmade mannequin.
Description: The group, who was given theory training with the e learning method, will be taught to make pillows and plastic bottles and cpr mannequins, and they will be asked to practice. Knowledge and skills assessment will be made before, immediately after and 1 month after the training.
Study NCT05610332 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: Camrelizumab One course will last 21 days. Given once every 3 weeks at a dose of 200 mg.
Study NCT05610332 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albumin Taxol
Description: Albumin paclitaxel was administered intravenously (without pretreatment) for 30 min on the first day of each cycle
Study NCT05610332 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FLOT scheme
Description: Docetaxel 50mg/m2, ivgtt, d1; Oxaliplatin 85 mg/m2, ivgtt, d1; Calcium folinate 200mg/m2, ivgtt, d1; 5-fluorouracil 2600mg/m2, 24h civ, d1,~4 cycles before and after operation, q2w
Study NCT05610332 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FLOT scheme
Description: Docetaxel 50mg/m2, ivgtt, d1; Oxaliplatin 85 mg/m2, ivgtt, d1; Calcium folinate 200mg/m2, ivgtt, d1; 5-fluorouracil 2600mg/m2, 24h civ, d1,~4 cycles before and after operation, q2w
Study NCT03810131 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 'A Bite of ACT' (BOA)
Description: An online Acceptance and Commitment Therapy transdiagnostic psychoeducational intervention called 'A Bite of ACT' (BOA)
Study NCT06586047 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PET imaging
Description: Imaging with FDG PET/CT and Pyl PET/CT
Study NCT06592391 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: educational innovation dynamic school day
Description: Schools will form a community of practice, and will be supported with regular workshop to develop a dynamic school day that matches the local context.
Study NCT06592391 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: e-learning on a dynamic school day
Description: Schools will form a community of practice, and will develop a dynamic school day that matches their local context using e-learning materials
Study NCT06592391 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: expert schools
Description: Schools that have developed a local dynamic school day without additional support
Study NCT04774094 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zavicefta, Ceftazidime-Avibactam
Description: Participants will receive CAZ-AVI (2000 mg of ceftazidime and 500 mg of avibactam) administered by IV infusion in a volume of 100 mL at a constant rate over 2 hours.
Study NCT05484635 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic laparoscopy and inguinal mesh removal
Description: Surgical examination and treatment of groin pain following inguinal hernia surgery by surgical exploration with a laparoscope or removal of mesh laparoscopically
Study NCT05484635 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Diagnostic laparoscopy
Description: Surgical examination through laparoscopy without removal of mesh
Study NCT05715931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab, 240 mg IV infusion on Day 1 of each 21 day cycle for 3 cycles prior to surgery and 3 cycles after surgery.
Study NCT05715931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: Trastuzumab, 8 mg/kg IV loading dose at 1st administration and then 6 mg/kg IV on Day 1 of each 21 day cycle for 3 cycles before surgery and 3 cycles after surgery. The first administration of trastuzumab after surgery should also be given at the loading dose of 8 mg/kg.
Study NCT05715931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5-FU, leucovorin, docetaxel, oxaliplatin (FLOT)
Description: Pre-operative treatment 4 cycles and post-operative treatment 4 cycles:~Docetaxel 50 mg/m², IV on day 1 of each 14 day cycle; Oxaliplatin 85 mg/m² , IV on day 1 of each 14 day cycle; Leucovorin 200 mg/m² or Levoleucovorin 100 mg/m², IV on day 1 of each 14 day cycle; 5-FU 2600 mg/m², IV over 24 h on day 1 of each 14 day cycle.
Study NCT04730804 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALXN1830
Description: ALXN1830 will be administered as SC infusion(s).
Study NCT04730804 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as SC infusion(s).