AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05686928 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetaphil Healing Ointment
Description: Topical ointment application twice daily
Study NCT04891445 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nursing monitoring program
Description: A clinical pathway will be activate that allows all the necessary interventions, once the person is diagnosed, to be carried out on the same day, and a mental health nursing team will monitor the entire process.
Study NCT04891445 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: As usual
Description: Referral to the family doctor for a request for follow-up by the gastroenterologist. The specialist prescribes the tests for the definitive diagnosis that will take place in other units (with their corresponding appointments). After this, the patient will return to the specialist to establish the treatment to follow. Pharmacological treatment will be dispensed at the hospital pharmacy (collected once a month until completion of treatment and confirmation of cure). This last step of the treatment will be done in a new consultation at the gastroenterology service after blood tests to verify the disappearance of the viral load.
Study NCT06467292 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: continuous theta-burst stimulation (cTBS)
Description: cTBS stimulation will be applied to different areas of the brain following learning. Stimulation will take place following learning in order to block motor memory retention.
Study NCT06467292 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adaptation
Description: Auditory adaptation in speech
Study NCT06467292 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Single pulse Transcranial magnetic stimulation (TMS)
Description: TMS will be delivered 10 times in each motor evoked potentials (MEP) recording block.
Study NCT06467292 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: fMRI
Description: To assess functional connectivity patterns between regions that predict learning.
Study NCT06491433 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: H2-BP
Description: The patient will have the test device applied to one wrist to measure blood pressure and the control device applied to the upper arm of the same arm to measure blood pressure.~1. H2-BP: The test device is placed on the wrist and presses a button to start pressurising. When the measurement is complete, the systolic and diastolic blood pressure is displayed on the screen.~2. big ben® Sphygmomanometer: The cuff is placed on the upper arm and the pump is pressed manually to inflate. 2 measurers will measure systolic and diastolic blood pressure by connecting 2 stethoscopes separately to one cuff.~Due to the external nature of the study medical device, it is not possible to blind subjects and investigators, so that subjects and measurers are aware of the allocation. Therefore, blinding of subjects and measurers will not be used in this study.
Study NCT05797142 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality glasses
Description: Beginning 1-2 minute before the start of the procedure, the patients will be watched (30 minutes) with an android mobile phone inserted into the Cardboard Super Flex Binoculars Glasses, with a music background, licensed product Secret Garden, during the procedure (30 minutes).
Study NCT05472259 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Only administered in the investigational arm (Nalirinox): a dose of 60 mg/m² is administered in combination with nanoliposomal irinotecan, 5FU and Leucovorin
Study NCT05137652 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Radiofrequency ablation of medial nerve using single needle approach
Description: The primary outcome is to study the efficacy of the described technique which creates a lesion that we estimate to be 11.0-mm wide and 11.6-mm long along the course of the medial branch adjacent to the SAP ensuring adequate coverage and treatment using VAS score. Responder status was defined as a 30% or greater improvement in VAS pain score from the pre-procedural VAS pain score. Outcomes were summarized by means and standard deviations for continuous outcomes, and frequencies (%) for categorical outcomes.
Study NCT04995536 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CpG-STAT3 siRNA CAS3/SS3
Description: Given intratumorally
Study NCT04995536 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo radiation therapy
Study NCT05788055 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Stool Analysis
Description: Stool Analysis to detect H.Pylori Antigen in Stool
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: DA-8010 Placebo
Description: Participants receive placebo to match DA-8010 orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DA-8010 Placebo
Description: Participants receive placebo to match DA-8010 orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-8010 2.5mg
Description: Participants receive DA-8010 2.5mg orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-8010 5mg
Description: Participants receive DA-8010 5mg orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Solifenacin 5mg
Description: Participants receive solifenacin 5 mg orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Solifenacin succinate placebo
Description: Participants receive placebo to match solifenacin 5 mg orally once a day.
Study NCT05282069 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Solifenacin succinate placebo
Description: Participants receive placebo to match solifenacin 5 mg orally once a day.
Study NCT05137652 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiofrequency ablation of medial nerve using three needle approach
Description: The primary outcome is to study the efficacy of the described technique by maximizing the lesion size (compared to control group) along the course of the medial branch adjacent to the SAP ensuring adequate coverage and treatment using VAS score.
Study NCT05036993 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coaching
Description: Faculty will be paired with a certified coach who is also a faculty member and receive 6 sessions of coaching over 3 months
Study NCT05605262 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Manukamed - Manukapli 100% sterile honey wound dressing - Premium medical grade 16+ Leptospermum Scoparium New Zealand honey
Description: After surgical reconstruction of the tympanic membrane by grafting, Manukamed - Manukapli 100% Sterile honey wound dressing is applied onto the gelfoam to close the area, followed by an antibiotic tampon.
Study NCT06483971 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Oral Isotretinoin
Description: 20 mg/kg/day that affects sebaceous glands and is used to treat severe acne Frequency: Once daily
Study NCT06483971 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: 250 mg on laternate day/3 months Frequency: Once or twice daily
Study NCT05570344 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: rTMS uses powerful (1.0-2.5 Tesla), focused magnetic field pulses to induce electrical currents in neural tissue noninvasively, via an inductor coil placed against the scalp.
Study NCT05570344 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS) Plus Text4Support
Description: rTMS uses powerful (1.0-2.5 Tesla), focused magnetic field pulses to induce electrical currents in neural tissue noninvasively, via an inductor coil placed against the scalp.~Text4Support:~Text4Support is one of the ResilienceNHope suites of supportive text messaging programs delivered by the Global Psychological eHealth Foundation \[80\]. The program allows users to receive daily supportive text messages which have been written by a team of cognitive-behavioral therapists and mental health professionals in collaboration with users of mental health services. The aim of this Text4Support depression program is to enhance positively the mood of patients with clinical depression. The program operates through the use of positive reinforcement to correct distorted or negative thought patterns.
Study NCT06481956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ribociclib Oral Tablet
Description: Patients with advanced breast cancer with at least one evaluable lesion and histologically proven invasive breast cancer were eligible for inclusion. Histopathologically positive for HER2 (IHC 3+, or IHC 2+ with fluorescence in situ hybridization (FISH) positive, either primary or metastatic. Patients with advanced breast cancer must have previously received first-line therapy or initial rescue therapy and have been treated with trastuzumab against HER2.
Study NCT05925036 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesenchymal stem cells
Description: Autologous bone marrow derived MSCs
Study NCT05925036 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Controls
Study NCT05117307 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine 0.25% Injectable Solution
Description: Ultrasound-guided block with 20 ml %0.25 bupivacaine, per side
Study NCT06329765 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise with CUped - a motor-assisted, split crank pedaling device and undergo 50 m of gait training.
Description: Exercise with CUped - a motor-assisted, split crank pedaling device and undergo 50 m of gait training.
Study NCT03409328 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIV and substance use prevention
Description: The intervention content will be developed through formative research during the initial phase of the study. However, the intervention will address: bisexual-inclusive sexual health education, unique influences of risk behavior among bisexual adolescents, and skills to cope with bisexual stigma and to increase acceptance of one's bisexual identity.
Study NCT05156866 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TORL-2-307-ADC
Description: antibody drug conjugate
Study NCT05716061 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacral ESPB
Description: Cadaver study
Study NCT05716061 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sacral ESPB
Description: Cadaver study
Study NCT06317753 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: Participants allocated to the Aerobic condition will be following a 4 month-intervention aerobic exercise protocol of 3 weekly interleaved sessions with a 50 minutes duration
Study NCT06317753 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Agility-Cognitive Exercise
Description: Participants allocated to the Agility-Cognitive condition will be following a 4 month-intervention agility-cognitive exercise protocol of 3 weekly interleaved sessions with a 50 minutes duration
Study NCT06317753 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Stretching/relaxation
Description: Participants allocated to the stretching control condition will be following a 4 month-intervention protocol of 1 weekly session with a 50 minutes duration
Study NCT03984539 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioural Therapy-Enhanced
Description: CBT-E is a 20-session transdiagnostic eating disorders treatment based on the principles of cognitive behavioural therapy which has been developed over the past 40 years. The treatment focusses on tracking and modifying eating behaviours, providing psychoeducation, addressing overvaluation of weight and shape, body image, food restriction and restraint, emotion regulation, and relapse prevention.
Study NCT03984539 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy-Ten
Description: CBT-T is a 10-session treatment based on cognitive behavioural therapy. It was developed based on clinical experience as well as core components of evidence-based versions of CBT for eating disorders, including CBT-E. The aim of the intervention is to provide only the hypothesized critical elements of CBT for eating disorders so that the interventions can be provided quicker.
Study NCT06129643 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Conventional group
Description: conventional disinfection using 2.5% sodium hypochlorite and 17% EDTA
Study NCT06129643 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual laser group
Description: Er,Cr:YSGG intracanal laser irradiation to remove smear layer followed by diode laser for disinfection
Study NCT06129643 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Combined group
Description: 17% EDTA was used to remove smear layer followed by diode laser for disinfection
Study NCT06216067 — intervention group
Intervention type: DEVICE
Intervention: CALLISTO eye
Description: Cataract toric lens placement tool
Study NCT06216067 — intervention group
Intervention type: DEVICE
Intervention: Wavetec AnalyzOR
Description: Cataract toric lens placement tool
Study NCT04457765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Povidone-Iodine (PVP-I)
Description: 1.25% Povidone-Iodine (PVP-I) (also known as betadine) to be used pre-procedure in the operating room via irrigation into the nasal cavity to act as viricidal preparation for the procedure. 240mL of 1.25% PVP-I will be distributed evenly among the right and left nasal cavities using a a 70mL syringe.
Study NCT01235013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Maraviroc
Description: 150 mg of Maraviroc every 12 hours (300 mg daily) orally for 24 weeks
Study NCT06636019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Myopia control contact lens
Description: Myopia control contact lens is placed on the study eye.
Study NCT06571955 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implantation of LARS artificial grafted ligament to treat ACL injury
Description: Implantation procedure will be realized by a well-trained orthopaedic surgeon and will consist of ACL repair using LARS artificial grafted ligament.
Study NCT05026463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Inspiratory support level
Description: Inspiratory support is the pressure delivered by the ventilator during pressure support ventilation.
Study NCT06571955 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implantation of LARS artificial non-grafted ligament to treat ACL injury
Description: Implantation procedure will be realized by a well-trained orthopaedic surgeon and will consist of ACL repair using LARS artificial non-grafted ligaments.
Study NCT04677946 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Linoleic Acid Healthy Cookies
Description: High Linoleic Acid Healthy Cookies (containing about 9g of linoleic acid) 1 per day for 8 weeks
Study NCT05439603 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANC-501
Description: Five 10 mg capsules per day
Study NCT05937048 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Albumin
Description: 20% human albumin solution infusion, to raise and maintain serum albumin levels above 3.0 g/dl. Human albumin solution will be given to those enrolled in the study having serum albumin levels ≤ 3 g/dl to maintain the serum albumin levels above 3 g/dl.
Study NCT05937048 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Standard treatment that the patient would receive had they not been included in the trial.
Study NCT05940935 — intervention group
Intervention type: PROCEDURE
Intervention: Arterial Blood Gas Base Deficit
Description: The base deficit values in the preoperative, intraoperative and postoperative blood gases taken from the patients and the presence and severity of metabolic acidosis were evaluated. Metabolic acidosis severity was defined by base deficit levels: mild from -3 to -5, moderate from -5 to -10, and severe metabolic acidosis below -10.
Study NCT04683991 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subepithelial connective tissue graft
Description: A de-epithelialized connective tissue graft is harvested from the homolateral palate and transplanted around the implant.
Study NCT06336369 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: analyzing brown adipose tissue, body composition and metabolic health
Description: cooling procedure, PET-CT imaging, MR imaging, blood sampling, indirect calorimetry, thermograpy, impedance analysis
Study NCT04054323 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Intervention
Description: The physical activity intervention will include basic skill training during which the participant will be instructed on the use of (1) the activPAL physical activity device for the tracking of time spent sitting, standing, and walking, (2) tools to monitor exercise intensity, including ratings of perceived exertion, (3) an exercise calendar for setting a specific schedule for the completion of the home exercise program using the exercise videos posted on our website, (4) use of the exercise equipment that will be used in the home program (Therabands), and (5) strategies for reduction of sedentary behavior that target prolonged sitting and encourages frequent activity breaks. Duration of intervention is 6 months.
Study NCT05478642 — intervention group
Intervention type: OTHER
Intervention: The Hospital Anxiety and Depression Scale.
Description: The study was carried out on the basis of the National Military Medical Clinical Center Main Military Clinical Hospital. All patients participated in Operation Joint Forces and received gunshot wounds during combat operations.~A retrospective analysis of disease histories for the period from 2014 to 2021 was carried out. Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury.~Recruitment of patients for the prospective study was carried out in the period from 02.24.2022 to 05.24.2022. Data collection was carried out during the Russian invasion of Ukraine and the offensive on Kyiv.
Study NCT05979337 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empowered Relief
Description: This is a single-session (2-hour) behavioral intervention utilizing pain psychology principles (cognitive-behavioral therapy for pain, pain neuroscience education).~Class will take place over zoom and have up to 25 participants. The Zoom classes will not be recorded. Participant will be asked to have the camera on during the entire class for treatment course/class validity. Participants are not required to speak during the class but are welcome to ask questions.~Participants will complete daily diaries for 14 days prior to attending study classes, and another 14 days after completing study classes.~In addition, participants will complete questionnaires and information about medical and personal history, symptoms, mood, sleep, medication use, and ability to function in daily life.
Study NCT05979337 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education (HE)
Description: This is a single-session (2-hour) health education class reviewing principles of medically indicated self-management of migraine headaches (e.g., consistent dietary and hydration habits, exercise, understanding of and adherence to medical treatment regimens).~Class will take place over zoom and have up to 25 participants. The Zoom classes will not be recorded. Participant will be asked to have the camera on during the entire class for treatment course/class validity. Participants are not required to speak during the class but are welcome to ask questions.~Participants will complete daily diaries for 14 days prior to attending study classes, and another 14 days after completing study classes.~In addition, participants will complete questionnaires and information about medical and personal history, symptoms, mood, sleep, medication use, and ability to function in daily life.
Study NCT05979337 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Treatment as Usual
Description: Participants will complete questionnaires and information about medical and personal history, symptoms, mood, sleep, medication use, and ability to function in daily life. In addition, participants will complete daily diaries for 28 days.~If participants are interested in attending classes that were not part of this group assignment, participants will be invited to do so after completing the 6-month follow-up questionnaire.
Study NCT05684458 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Reiki
Description: Reiki, a non-invasive, free and safe complementary therapy method, is practiced with a series of hand positions held on the patient's body to help balance the life force energy.
Study NCT06097065 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Oral Glucose Tolerance Test
Description: Grouping based on detected oral glucose tolerance test results without any other intervention.
Study NCT04851912 — intervention group
Intervention type: OTHER
Intervention: Winterlight Apps
Description: Longitudinal speech recordings
Study NCT05682339 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quinine
Description: Quinine, which is a bitter compound, extracted from the bark of the cinchona tree and has been shown in our previous studies to lower blood glucose in doses of 300-600 mg, will be 'active' in this condition.
Study NCT05682339 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: L-isoleucine
Description: L-isoleucine, which is a branched-chain amino acid, and one of the building blocks of protein, therefore is part of our daily diet, will be 'active' in this condition.