AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05905536 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vitalstream
Description: The device will be placed on the subject and monitoring started in the holding room on the morning of surgery. Monitoring will continue postoperatively until the pulmonary artery catheter (PAC) is removed (Standard of Care) or discharged, or at study team discretion. At Intensive Care Unit (ICU) admittance and again 3 hours later a straight leg raise will be done to monitor for changes in hemodynamics.
Study NCT05667844 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: interoceptive mind-body exercise
Description: A interoceptive mind-body exercise program in a patient with Generalized Anxiety Disorder and Major Depressive Disorder based on a Multidimensional Assessment of Interoceptive Awareness. Each session of the body-mind intervention lasts 80 minutes and is supervised by physical education professionals. The intervention is divided in 4 parts, that are: Preparatory phase (reception) the subjects will be welcomed through subjective analyzes of the researcher; Initial phase (preliminares) Mindfulness, grounding, sensory stimulation and joint warm-up exercises are performed; main phase (exercises) stretching, mobility, posture and balance exercises are performed with full attention and listening after each exercise; Final phase (relaxation) breathing exercises, stretching exercises, body scanning and relaxation are performed.
Study NCT06505304 — intervention group
Intervention type: PROCEDURE
Intervention: Colonoscopy
Description: The colonoscopy will be performed at 3 or 6 months after surgery according to FC:~* In patients with FCP >=150µg/g at around 3 months after surgery, a colonoscopy will be immediately performed~* In patients with FCP \<150µg/g at around 3 months after surgery, the colonoscopy will be organized at 6 months after surgery~Colonoscopy will be performed using high definition white-light endoscopy (HD-WLE) followed by virtual chromoendoscopy (VCE). The neoterminal ileum, ileocolic anastomosis and right colon will be assessed.~A follow-up colonoscopy will be performed within 18 months after index colonoscopy, as standard of care.
Study NCT06505304 — intervention group
Intervention type: PROCEDURE
Intervention: Intestinal biopsies
Description: During index colonoscopy, at least 2 biopsies from each of the segments will be taken as standard of practice to assess inflammation in post-operative CD. Only in Irish sites, twelve biopsies - four in the area of ileocolonic anastomosis, four in the neo-terminal ileum and four in the colon just distal to the anastomosis- will be taken for research purposes, in addition to standard-of-care biopsies.
Study NCT06505304 — intervention group
Intervention type: PROCEDURE
Intervention: Confocal laser endomicroscopy
Description: pCLE with fluorescein injection will be performed during index colonoscopy, in centres where is available, to assess early alteration of the barrier function.
Study NCT06505304 — intervention group
Intervention type: PROCEDURE
Intervention: Intestinal ultrasound
Description: All patients will undergo a cross-sectional imaging test as part of their standard of care at 3 and 6 months after surgery. A follow-up IUS will be performed within 18 months after index colonoscopy, as standard of care.
Study NCT06505304 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Stool
Description: Stool samples will be collected at 3 and 6 months after surgery and used for faecal calprotectin analysis. Research stool will be collected during the visit of index colonoscopy and at 12 months after index colonoscopy for metagenomics (only in Irish sites).
Study NCT06485986 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DBS on/off
Description: DBS will be turned on and off for experimental periods to compare the effect of DBS on behaviour.
Study NCT06485986 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: DBS on/off
Description: DBS will be turned on and off for experimental periods to compare the effect of DBS on behaviour.
Study NCT04957420 — intervention group
Intervention type: DRUG
Intervention: Neupro
Description: Rotigotine Patches
Study NCT04184661 — intervention group
Intervention type: OTHER
Intervention: blood sample
Description: 25 mL blood sample will be collected on citrate tubes for osteoclastic analysis.
Study NCT05859048 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: NT-proBNP
Description: blood sample to measure N-terminal prohormone of B-type natriuretic peptide at local laboratory
Study NCT05859048 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: AI echocardiogram
Description: Artificial intelligence driven transthoracic echocardiogram
Study NCT05859048 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: electrocardiogram
Description: tracing of electrical cardiac activity of the heart
Study NCT05859048 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cardiovascular physical examination
Description: basic physiological measurements to include height (cm), weight (kg) and hip circumference (cm) and blood pressure (mmHg)
Study NCT05029401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DMX-1002
Description: Investigation of the safety, tolerability and pharmacokinetics (PK) in healthy volunteers (Stage 1 - single blind), and the efficacy, safety, tolerability and PK in opioid-dependent patients (Stage 2 - double blind)
Study NCT05029401 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo to the IMP (DMX-1002)
Study NCT05029401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo to the IMP (DMX-1002)
Study NCT05085067 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: auto-crossed-linked hyaluronic acid gel
Description: infusing auto-cross linked hyaluronic acid gel into intrauterine cavity after hysteroscopic treatment because of retained products of conception
Study NCT05715398 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR790+anlotinib
Description: BR790 will be administered orally, variable dose on Day 1 of each 21-day cycle， Anlotinib will be administered as PO fixed dose on Day1-14 of each 21-day cycle
Study NCT05191810 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational information
Description: Educational information about non-pharmacological supporting treatment of functional constipation, involving recommendation of adequate for age fluid intake
Study NCT04933292 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylprednisolone and Mycophenolate mofetil
Description: Methylprednisolone combination of mycophenolate mofetil
Study NCT04933292 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylprednisolone and azathioprine
Description: Methylprednisolone combination of azathioprine
Study NCT06167486 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SG2918
Description: The SG2918 will be administrated by intravenous infusion every 3 weeks
Study NCT04774887 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HPV vaccine, Merck
Description: Vaccination against HPV will be offered to 900 children/grandchildren aged 9 through 18 of women attending the Community Meetings.
Study NCT05079386 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: New Voice Prosthesis
Description: Replacement of the current prosthesis with the experimental device and use the New Voice Prosthesis for the duration of two weeks with the option of leaving the device in situ until replaced for device failure or other reason, with a maximum of 12 months.
Study NCT06021808 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thoracoscopic LAA clipping
Description: The surgeons measured the length of the base of the LAA, an appropriately sized LAA clip is then inserted with the aid of a thoracoscope and placed parallel to the base of the LAA.
Study NCT06021808 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Novel oral anticoagulant
Description: For patients with creatinine clearance ≥50 ml/min, oral rivaroxaban 20 mg daily was administered, whereas for patients with creatinine clearance between 30-49 ml/min, oral rivaroxaban 15 mg daily was administered.
Study NCT04926116 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK3280
Description: Active Substance: AK3280, Pharmaceutical Form: Tablet, Route of Administration: Oral
Study NCT04926116 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Active Substance: Placebo, Pharmaceutical Form: Tablet, Route of Administration: Oral
Study NCT05927116 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile phone app-based intervention for supporting and empowering parents of children with autism spectrum disorder (ASD)
Description: TRIP is a mobile app-based intervention comprises of a 6-week structured training on mindfulness and educational modules on ASD parenting skills.
Study NCT05372133 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: Children will be provided with morphine for at-home pain management following supracondylar fracture repair
Study NCT05100979 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Art of Medicine Series
Description: The Art of Medicine Series is a smartphone-based educational tool focused on teaching communication strategies to clinicians and patients.
Study NCT06036199 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Focused Ultrasound Pallidotomy
Description: Use of ExAblate Transcranial MR guided Focused Ultrasound as a tool for creating bilateral or unilateral lesions in the globus pallidus (GPi) in patients with treatment-refractory secondary dystonia due to dyskinetic cerebral palsy
Study NCT05882916 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HIV self-testing
Description: Oral fluid-based HIV self-test kits for secondary distribution
Study NCT05882916 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral economic 'nudges'
Description: Salient information for men included with the self-test kit on clinic location and hours within their cluster, and pilot-tested messaging on the importance of early ART initiation, and the availability and benefits of PrEP
Study NCT06205433 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: IHSS Basic Training
Description: The intervention is the Center for Caregiver Advancements 30-hour IHSS Basic training course.
Study NCT03605654 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MDR-102
Description: Enriched CD34+ hematopoietic stem cells and defined dose of CD3+ T-cells
Study NCT03605654 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Immunosuppressive Agents
Description: Standard Anti-Rejection Medications that would be given to kidney transplant recipients who are outside the study
Study NCT05613907 — intervention group
Intervention type: OTHER
Intervention: CLTI Clinic
Description: This is a specialist clinic designed to assess and manage patients with CLTI.
Study NCT04846231 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Fish Oil, Cinnamon, Garlique,Turmeric, Plant Sterol, Red Yeast Rice
Description: Subjects will be randomized to a Statin (Rosuvastatin 5 mg), a placebo, or a dietary supplement (Fish oil, Cinnamon, Garlic, Turmeric, Plant sterol, Red yeast rice).
Study NCT06505304 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood
Description: Blood will be collected at 3 and 6 months after surgery and used as standard of care. Research blood will be collected during the visit of index colonoscopy and at 12 months after index colonoscopy for research - i.e. proteomic, genomic, cell experiments (only in Irish sites).
Study NCT04846231 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rosuvastatin
Description: Subjects will be randomized to a Statin (Rosuvastatin 5 mg), a placebo, or a dietary supplement (Fish oil, Cinnamon, Garlic, Turmeric, Plant sterol, Red yeast rice).
Study NCT04846231 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will be randomized to a Statin (Rosuvastatin 5 mg), a placebo, or a dietary supplement (Fish oil, Cinnamon, Garlic, Turmeric, Plant sterol, Red yeast rice).
Study NCT04992026 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: robot assisted laparoscopic prostatectomy + enlarged pelvic lymph node dissection
Description: Robot assisted laparoscopic prostatectomy + enlarged pelvic lymph node dissection will be performed.
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 1.Abiraterone Acetate Tablets
Description: 1000mg(4 tablets, 250mg per tablet) daily for 6 cycles
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1.Abiraterone Acetate Tablets
Description: 1000mg(4 tablets, 250mg per tablet) daily for 6 cycles
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisone Acetate Tablets
Description: 5 mg oral low dose prednisone taken along with Abiraterone Acetate Tablets
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone Acetate Tablets
Description: 5 mg oral low dose prednisone taken along with Abiraterone Acetate Tablets
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Luteinizing Hormone-Releasing Hormone Analog
Description: Hypodermic injection of Luteinizing Hormone-Releasing Hormone Analog every 4 weeks including goserelin, leuprolide, triptorelin ect.
Study NCT04992026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Luteinizing Hormone-Releasing Hormone Analog
Description: Hypodermic injection of Luteinizing Hormone-Releasing Hormone Analog every 4 weeks including goserelin, leuprolide, triptorelin ect.
Study NCT05018689 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aevidum curriculum
Description: The Aevidum curriculum will be delivered to 9th grade students at participating high schools in both study arms. All school staff who plan to deliver the curriculum will participate in a web-based training workshop with the Aevidum Executive Director.
Study NCT05018689 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Club
Description: Schools will identify ten students interested in participating in an Aevidum club. Following training of interested students, schools are asked to commit to running two Aevidum club activities during the school year.
Study NCT05421676 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100)
Description: This will take place between gestation of 27w0d - 29w6d. The balloon will be removed at approximately 34 weeks gestation.
Study NCT06241300 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chicago Parent Program
Description: Chicago Parent Program is an evidence-based group parenting intervention designed to reduce disruptive behavior in young children (2-8 years old).
Study NCT05030584 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elinzanetant (BAY3427080)
Description: 120 mg elinzanetant orally once daily
Study NCT05030584 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo orally once daily.
Study NCT06505304 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Saliva
Description: Saliva will be collected during the visit of index colonoscopy and at 12 months after surgery for research - i.e. optical spectroscopy (only in Irish site)
Study NCT06505304 — intervention group
Intervention type: OTHER
Intervention: Clinical follow-up
Description: Patients will be followed-up at 6, 12 and 24 months after index endoscopy. Patients will be evaluated in clinic or by telephone call and the disease will be reassessed. The following scores will be repeated: Harvey Bradshaw Index (HBI) and CD Activity Index score (CDAI). Participants will give an update on their medication use.
Study NCT06033534 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: STIMULAN
Description: Procedures:~Surgical repair of the open fracture, as per standard-of-care guidelines. Insertion of the STIMULAN device at the site of the fracture. Standard post-operative care, including monitoring of inflammatory markers and clinical signs of infection.
Study NCT06194305 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CBIT
Description: Participants will receive 8 sessions delivered weekly over 10 weeks. All sessions will be video recorded. CBIT components are: 1) Psychoeducation about tics, 2) Functional interventions, 3) Competing response (CR) training, 4) Social support: supportive people (e.g., parent, teacher) , 5) Motivational enhancements, 6) Homework: is assigned each session and typically involves self-monitoring and CR practice. Participants will complete a brief daily homework tracking log in REDCap.
Study NCT05691387 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Thera PEP
Description: Sitting comfortably, patients receiving Thera PEP will be told to place dental cotton swabs between their cheek and gum, and then under their tongue, to absorb saliva and prevent contamination of the collected sputum by the patient's own saliva. The diameter of the opening will be modified to achieve a ventilation rate of 1:4. The patient will be taught to take in a larger than normal breath but not fill the lungs to capacity in order to maintain a tight seal during exhalation. After completing ten PEP breaths, the patient will have the mouthpiece removed and be instructed to do two or three puff coughs. When secretions need to be brought up, a good cough will do the trick. During the duration of the treatment, which will last around thirty minutes, the patient will be asked to complete three cycles of ten breaths each.
Study NCT05691387 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ACBT and PLB
Description: On the day of the ACBT, the patient will be taught to place dental cotton swabs between the cheek and gum, as well as beneath the tongue, to absorb saliva and prevent contamination of the collected sputum by saliva. Throughout the treatment, the patient will be urged to maintain a comfortable sitting position. The patient will then be instructed to perform PLB at a normal tidal volume (for approximately 6 breaths), followed by 3-4 deep inspirations with relaxed exhalation (thoracic expansion exercise), and finally, another period of breathing control, i.e. PLB, followed by FET, i.e. a deep breath in and a huff cough, followed by a medium breath in and a huff cough again. Approximately thirty minutes will pass over the course of this session.
Study NCT06184178 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Socio-health care
Description: Socio-health care under TEC-MED model and an integral assessment
Study NCT05066412 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CD45RAneg cells, prepared from mononuclear cell leukapheresis by CliniMACS® technology
Description: CD45RAneg cells, prepared from mononuclear cell leukapheresis by CliniMACS® technology
Study NCT05285228 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: effect of choice on cooperation (pseudoalternative)
Description: For the test group, before the standard check-up starts, the participant is given the choice of selecting the taste of the fluoride varnish (Profluorid VOCO, Germany) from a range of about five flavors (Melon, Caramel, Cherry, Bubble gum, Mint), which will be applied at the end of the visit. Post-placement instructions provided by the manufacturer will be given to the caregiver and the child and questionnaires will be handed out.
Study NCT05285228 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: given fluoride varnish (control)
Description: For the control group the participant is provided with a given taste of the fluoride varnish (Profluorid VOCO, Germany) from a range of about five flavors (Melon, Caramel, Cherry, Bubble gum, Mint) according to the randomization list.
Study NCT05749640 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Precontoured sectional matrix EZ COAT
Description: All teeth will be treated with (Palodent ® plus sectional matrix system) (sectional matrix, biting ring, plastic diamond wedge)
Study NCT05749640 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PerForm™
Description: Treated with (PerForm™) as Contact Forming Instrument with (Palodent ® plus sectional matrix system)
Study NCT05749640 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: AdDent Trimax™
Description: Treated with (AdDent Trimax™) as Contact Forming Instrument with (Palodent ® plus sectional matrix system)
Study NCT05749640 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Contact Pro™
Description: Treated with (Contact Pro™) as Contact Forming Instrument with (Palodent ® plus sectional matrix system)
Study NCT06431425 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eCG Family Clinic
Description: The DNA-poli is an online tool which is designed as an addition to the current genetic counseling method to make the process more efficient and to increase the uptake without compromising counseling quality. Probands can invite their at-risk family members by entering their email addresses. The family members are invited to the DNA-poli via which they can get all the information needed to make a well-considered decision about genetic testing. The information is provided in different formats, for example via a virtual assistant and via videos, which they can evaluate at their own pace, and which can be reread or rewatched. Afterwards they can request an appointment with a health care professional and make a definite decision about genetic testing.
Study NCT05115435 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: neuro linguistic programming
Description: Sub modality Technique: People experience the world with their five senses, and the thoughts that an individual creates in his brain about a situation are coded with these five senses. When these encodings change, the individual's perception of the situation will also change
Study NCT05753462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phase 1, SQY51
Description: SQY51 is administered by intravenous infusion.