AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06544915 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Synbiotic, Probiotic, Placebo
Description: Use of dietary supplements to improve gut microbiome and cardiometabolic health
Study NCT06544915 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Synbiotic, Probiotic, Placebo
Description: Use of dietary supplements to improve gut microbiome and cardiometabolic health
Study NCT05225922 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Communication Partner Training
Description: This intervention aims to improve the language, communication, participation and overall quality of life of the Person with Aphasia.
Study NCT05225922 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Speech and language Therapy
Description: This group will receive usual speech and language therapy session.
Study NCT05966519 — intervention group
Intervention type: DEVICE
Intervention: Total Knee Replacement (TKR)
Description: Damaged cartilage of knee due to degenerative disease is replaced with metallic and plastic protheses
Study NCT04418466 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Risperidone
Description: Risperidone Implant
Study NCT06174740 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music-cued audiovisual motor training
Description: In addition to visual cues, music stimuli guide finger sequence movement both rhythmically (temporal component) and sonically (pitch-finger alignment).
Study NCT06174740 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Visually-cued motor training
Description: Visual cues guide finger sequence movement by indicating which finger to move in alignment with the position and of the visual cue.
Study NCT06642675 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent theta burst stimulation(iTBS)
Description: By using the TMS Navigation System, the iTBS will be targeted at the left Supramarginal Gyrus.iTBS will be performed using Magstim Rapid² stimulator, parameters are set to triplet 50Hz bursts, repeat at 5Hz, 2s seconds on and 8 seconds off, 1800 pulses per session, intensity of 90% resting motor threshold(RMT), total duration of 10 minutes.
Study NCT06642675 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: Patients in sham group would receive the same intervention procedure as the active ITBS group, but the coil will be replaced with sham coil, which provides the sensation of TBS without enough magnetic energy to reach the cortex.
Study NCT06413914 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral Therapy
Description: Cognitive behavioral therapy is the psychological approach in this study. It is associated with better outcomes of rehabilitation for long-term pain in general, reduced pain intensity and less use of medication and health services, sustaining factors that provide an understanding of how thoughts and feelings affect the experience of pain. An important aim is also a reduction in pain-related rumination and worry and changed metacognition that maintains inhibiting behavior and thought patterns.~A workbook for pain has been developed. It contains knowledge about pain and pain management, describes measures and homework from session to session. The treatment consists of 8 sessions with 7 weekly sessions + 1 booster session 2 months after the end of treatment.~.
Study NCT05505916 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KVD900 600 mg
Description: KVD900 Tablet 600 mg (2 x 300 mg)
Study NCT05505916 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KVD900 300 mg
Description: KVD900 Tablet 300 mg
Study NCT06153082 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ROTEM
Description: In ROTEM group if CT EXTEM >80S FFP at dose of 10ml/kg or PCC 20-25IU/kg ,if MCF EXTEM \<35 and MCF FIBTEM \<8 CRYO or Fibrinogen concentrate, if MCF EXTEM\<35 and MCF FIBTEM >8 Platelet, CL LY>50 Trenaxemic acid
Study NCT05387746 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Caring Science, Mindful Practice and Reiki Training
Description: Participants will complete a) 4 week internet-based course on Caring Science Mindful Practice and b) 12 hour Reiki training. The participants will also complete online post-training survey with the same questions included in pre-training survey.
Study NCT06153082 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Thromboelastography
Description: Patients in the TEG group received blood components using the following triggers: FFP at a dose of 10 mL/kg of ideal body weight when reaction time (R time) was greater than 10 minutes; a single-donor apheresis platelet (SDAP) unit, which corresponds to approximately 6 to 8 pooled units of PLTs, transfused when the maximum amplitude (MA) was less than 55 mm; and cryoprecipitate (5 pooled units) transfused when the alpha angle was less than 45°.
Study NCT05000710 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Durvalumab administered IV over 60 minutes at a dose of 1500 mg every 4 weeks
Study NCT05000710 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Tremelimumab administered IV over 60 minutes at a dose of 300 mg , twice: at C1D1 and C4D1
Study NCT05000710 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Low dose irradiation
Description: 21 days after the first immunotherapy treatment 11 fractions of 3 Gy will be administrated to metastatic or primary lesion/s over 2 weeks and one day
Study NCT04530799 — intervention group
Intervention type: OTHER
Intervention: Identification of biomarkers for IAPA via patient sampling
Description: Blood, BAL, microbiome
Study NCT04240561 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High level of signal manipulation
Description: Hearing aid will be programmed to a high level of signal manipulation.
Study NCT04240561 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low level of signal manipulation
Description: Hearing aid will be programmed to a low level of signal manipulation.
Study NCT05210816 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment Therapy
Description: Acceptance and Commitment Therapy Based Intervention Program was applied to the intervention group in eight sessions online. Each session will last an average of 60-90 minutes. There will be two sessions for one group per week.
Study NCT05189665 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extraperitoneal high sacral ligament suspension surgery
Description: The extraperitoneal high sacral ligament suspension surgery is to shorten the bilateral uterosacral ligaments .
Study NCT05189665 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacrospinous ligament fixation
Description: The sacrospinous ligament fixation surgery is to open the front and back peritoneum through the vagina and shorten the bilateral uterosacral ligaments.
Study NCT05664373 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Coronally advanced flap and deepithelized free gingival graft
Description: Free gingival grafts, de-epithelialized intraoraly or extraoraly in combination with coronally advanced flap will be used in the treatment of multiple gingival recessions.
Study NCT05664373 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coronally advanced flap and deepithelized free gingival graft
Description: Free gingival grafts, de-epithelialized intraoraly or extraoraly in combination with coronally advanced flap will be used in the treatment of multiple gingival recessions.
Study NCT06554769 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non rigid indirect anchorage connection
Description: a nonrigid connection is placed between the miniscrews and the second premolar to prevent mesial tooth movement.
Study NCT06554769 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: rigid indirect anchorage connection
Description: a rigid connection is placed between the miniscrews and the first molar to prevent mesial tooth movement.
Study NCT06444243 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: Psilocybin is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi.
Study NCT06444243 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Niacin
Description: A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacin helps some enzymes work properly and helps skin, nerves, and the digestive tract stay healthy. Niacin is found in many plant and animal products.~Niacin will be used at a concentration of 250mg as an active control.
Study NCT05385042 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Sangobion and Thiamine Hydrochloride
Description: Prophylactic dietary supplements: 1 capsule of Sangobion + separate Thiamine Hydrochloride tablet 100mg per day for 12 weeks.~Then non-anaemic pregnant women will continue with prophylactic nutritional supplements until delivery.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Determination of Foot Deformity Level
Description: One of the methods used in our study to determine the presence and degree of pes planus is the navicular drop test.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Determination of Foot Deformity Level
Description: One of the methods used in our study to determine the presence and degree of pes planus is the navicular drop test.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Foot Function Index
Description: Evaluation of Foot Function
Study NCT05385042 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Sangobion, Thiamine hydrochloride and Vitamin B12
Description: Treatment dietary supplements: 3 capsules of Sangobion + separate Thiamine Hydrochloride tablet 100mg, Vit B12 100mcg per day for 12 weeks.~If experience a therapeutic increase of 3% Haematocrit within 28 days (responders), they will continue with prophylactic nutritional supplements until delivery.~If no affect in Haematocrit level within 28 days (non-responders; defined by trimester of diagnosis), they will be investigated for their serum ferritin and if this is low (\<15ng/mL) intravenous (iv) iron supplement (Venofer®) will be provided. The dose will be calculated for the individual concerned (required iron dose (mg) = (2.4 x (target Hb of 11g/dL (Ht 33%) x pre-pregnancy weight (kg) +1000mg for replenishment of stores). Doses will be administered by slow iv infusion 200 mg per dose (maximum of 3 doses per week).~Following treatment they will continue with prophylactic nutritional supplements.
Study NCT05216406 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: 5-HTP
Description: CLEANMOOD is an organic 5-Hydroxytryptophan (5-HTP) ingredient.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Foot Function Index
Description: Evaluation of Foot Function
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: UFAA-International Physical Activity Questionnaire
Description: To determination of physical activity level.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: UFAA-International Physical Activity Questionnaire
Description: To determination of physical activity level.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Diaphragm ultrasound measurements
Description: Rehabilitative ultrasound imaging is a method frequently used by physiotherapists to assess muscle function.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Diaphragm ultrasound measurements
Description: Rehabilitative ultrasound imaging is a method frequently used by physiotherapists to assess muscle function.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: NeuruCom Balance Master Balnce and Performans Test
Description: Balance master will be used for postural stability, static and dynamic balance measurements.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NeuruCom Balance Master Balnce and Performans Test
Description: Balance master will be used for postural stability, static and dynamic balance measurements.
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Plantar Pressure Assessment
Description: When assessing plantar pressure, postural control will be evaluated statically or dynamically, through examination of the behavior of the center of plantar pressure (COP).
Study NCT05216406 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Maltodextrin capsule
Study NCT06491212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Plantar Pressure Assessment
Description: When assessing plantar pressure, postural control will be evaluated statically or dynamically, through examination of the behavior of the center of plantar pressure (COP).
Study NCT04704739 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG1205 film-coated tablets
Description: Single oral dose of GLPG1205
Study NCT04704739 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-GLPG1205 solution for infusion
Description: A 15-minute IV infusion of \[14C\]-GLPG1205
Study NCT04704739 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLPG1205 capsules
Description: Single oral dose of GLPG1205 as solid formulation
Study NCT06261996 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fospropofol
Description: Fospropofol is administered after admission to the room at a pumping rate of 1 mg/kg/h.
Study NCT06261996 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Fospropofol
Description: Fospropofol is administered after admission to the room at a pumping rate of 1 mg/kg/h.
Study NCT05952089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Danicamtiv
Description: Specified dose on specified days
Study NCT05952089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Specified dose on specified days
Study NCT05125562 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ExoFlo
Description: Patients will be randomized to one of three infusions: (1) Normal Saline 100 mL, (2) Normal saline 90 mL and ExoFlo 10 mL, which is 7x1011 EVs, and (3) Normal saline 85 mL and ExoFlo 15 mL, which is 10.5x1011 EVs. The study intervention will only be dosed on day=1
Study NCT05125562 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: ExoFlo
Description: Patients will be randomized to one of three infusions: (1) Normal Saline 100 mL, (2) Normal saline 90 mL and ExoFlo 10 mL, which is 7x1011 EVs, and (3) Normal saline 85 mL and ExoFlo 15 mL, which is 10.5x1011 EVs. The study intervention will only be dosed on day=1
Study NCT06168318 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VH4004280 Formulation A
Description: Oral administration of VH4004280 Formulation A in fasted or fed conditions.
Study NCT05433194 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ABO1009-DP
Description: Vaccine
Study NCT05628584 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: High FODMAP diet with metformin
Description: Controlled High FODMAP diet (15g/day) from day 1-10, metformin XR 1000mg daily day 6-10 for each treatment period
Study NCT05576844 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 8-week interpersonal and social rhythm intervention
Description: The development of the intervention strategies are based on social rhythm theory, interpersonal and social rhythm therapy, and previous research results, and the intervention aims to improve sleep by stabilizing participants' social rhythm and increasing the amount of interpersonal communication.
Study NCT05576844 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Control group participants received usual care, including daily disease management and routine drug guidance.
Study NCT06168318 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VH4004280 Formulation B
Description: Oral administration of VH4004280 Formulation B in fasted or fed conditions.
Study NCT05628584 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Low FODMAP diet with metformin
Description: Controlled low FODMAP diet (3g/day) from day 1-10, metformin XR 1000mg daily day 6-10 for each treatment period
Study NCT06273891 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Erythromycin
Description: Erythromycin 250 mg IV every 6 hours for 48 hours, followed by 250 mg PO or 333 mg PO every 8 hours for 5 days~in addition to Ampicillin 2 gm IV every 6 hours for 2 days followed by Amoxicillin 250 mg PO every 8 hours for 5 days
Study NCT06273891 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Azithromycin
Description: Azithromycin 1 gm PO once or 500 mg PO followed by 250 mg PO daily for a total of 5 days~in addition to Ampicillin 2 gm IV every 6 hours for 2 days followed by Amoxicillin 250 mg PO every 8 hours for 5 days
Study NCT05802264 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ABCI
Description: Subjects will receive ABCI via oral inhalation
Study NCT05802264 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive ABCI via oral inhalation
Study NCT05286762 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CTx-1301-Dexmethylphenidate 12.5 mg (titration only)
Description: Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg
Study NCT05957497 — intervention group
Intervention type: BIOLOGICAL
Intervention: Biological samples transport and analysis
Description: Biological samples transport and analysis
Study NCT05286762 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CTx-1301-Dexmethylphenidate 18.75mg (randomized fixed dose)
Description: Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg
Study NCT06168318 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VH4004280 Formulation C
Description: Oral administration of VH4004280 Formulation C in fasted or fed conditions.
Study NCT05286762 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CTx-1301-Dexmethylphenidate 25mg (randomized fixed dose)
Description: Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg, then week 2 to 25 mg
Study NCT05286762 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CTx-1301-Dexmethylphenidate 37.5 mg (randomized fixed dose)
Description: Subjects will be randomized at Visit 2 to CTx-1301 to 12.5mg, then week 1 to 18.75 mg, then week 2 to 25 mg, then week 3 to 37.5 mg
Study NCT05286762 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will be randomized at Visit 2 to Placebo
Study NCT06392633 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: spastic hand sugery
Description: Deformity correction can be performed with single event multilevel surgery, using a combination of soft tissue releases and lengthening, tendon transfers and joint stabilization procedures. In addition, selective and supraselective neurectomies can also be performed.
Study NCT06392633 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Botulinum Toxin A
Description: Treatment consists of periodic injections of the toxin into the spastic muscles. It causes reversible chemical denervation by preventing the release of acetylcholine vesicles at the neuromuscular junctions of the affected muscles.
Study NCT04803630 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT04803630 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04803630 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thermotherapy
Description: Undergo thermal therapy
Study NCT06199648 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: web-based documentation and advice
Description: Caregivers will be supported with a web-based documentation and advice system for home care for elderly people
Study NCT05243355 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Envafolimab and Chemotherapy and Recombinant Human Endostatin
Description: Envafolimab: 300 mg，D1，Q3W,until PD or intolerable toxicity Chemotherapy: Paclitaxel / NAB-Paclitaxel, 175 / 260mg / m2, D1, Q3w; Cisplatin: 75mg / m2, 1-3 days, or carboplatin: AUC 5, D1, Q3w, 4-6 cycles in total.~Recombinant Human Endostatin：210mg，CIV 72h，d1-3，Q3W，4-6 cycles in total.
Study NCT05916820 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tanzberger Exercises
Description: It consists of patients who will receive Tanzberger exercise 3 sessions per week for 4 weeks. e.g. Rolling on the ball forward, Back to back sitting.
Study NCT05916820 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor muscle training
Description: It consists of patients who will pelvic floor muscles exercise 3 sessions per week for 4 weeks. e.g. Assisted heel drop, Bridge, Dead Bug, Bird DOG
Study NCT04063410 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Angiography
Description: Undergo standard of care CTA
Study NCT04063410 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: MRI-Based Angiogram
Description: Undergo pPCA
Study NCT04063410 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies