AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05262738 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 50 Micrograms Vaginal Misoprostol (Intervention)
Description: Subjects will undergo cervical ripening with 50 micrograms of vaginal misoprostol every 4 hours.
Study NCT05262738 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 25 Micrograms Vaginal Misoprostol (Control)
Description: Subjects will undergo cervical ripening with 25 micrograms of vaginal misoprostol every 4 hours.
Study NCT06309654 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 12-week home-based circuit training (HBCT)
Description: Participants in the exercise group performed HBCT three times per week on non-consecutive days for 12 weeks. The first session was conducted at USM Hospital and participants were instructed how to perform the prescribed exercises in a correct form. In each session, participants performed seven exercises (two aerobic- and five resistance-based) in a circuit fashion, using bodyweight movements and adjustable dumbbells for varied weights, activating all the major muscle groups. In weeks 1-6, participants executed 15 repetitions for 2 rounds with 1 min passive rest between exercises and rounds. In weeks 7-12, participants executed 30 repetitions for 4 rounds with the same rest as prescribed in weeks 1-6. Each round lasted 10-15 min and the total session duration was 20-60 min, aiming to help participants adapt gradually to increasing training volume.
Study NCT06309654 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Standard of care (CONT)
Description: Providing education about the nature of OA, its progression, and strategies for symptom management.~Empowering individuals with self-management techniques, such as joint protection strategies, activity modification, and lifestyle changes (e.g., weight management, exercise).
Study NCT06581133 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alarm system
Description: Generic alarm system programmed to sound during the night to try to induce arousals from sleep.
Study NCT05438992 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine 0.25% Preservative-Free Injectable Solution
Description: local anesthetic drug injection for postoperative pain
Study NCT05049421 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography
Description: Full 2D and 3D echocardiography with special focus on right ventricular function
Study NCT05447260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Dosage based on platelet count
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ammoxetine hydrochloride enteric-coated tablets
Description: Ammoxetine hydrochloride enteric-coated tablets
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Duloxetine hydrochloride enteric-coated capsules
Description: Duloxetine hydrochloride enteric-coated capsules
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo to Ammoxetine
Description: Placebo to Ammoxetine
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to Ammoxetine
Description: Placebo to Ammoxetine
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo to Duloxetine
Description: Placebo to Duloxetine
Study NCT05018013 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo to Duloxetine
Description: Placebo to Duloxetine
Study NCT04576975 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: compare the use of ketamine versus dexmedetomidine when used as perioperative infusion in obese patients undergoing laparoscopic bariatric surgery regarding their analgesic efficacy as well as any side effects or drawbacks (PONV and effects on consciousness) that might associate with their use.
Study NCT04576975 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: compare the use of ketamine versus dexmedetomidine when used as perioperative infusion in obese patients undergoing laparoscopic bariatric surgery regarding their analgesic efficacy as well as any side effects or drawbacks (PONV and effects on consciousness) that might associate with their use.
Study NCT04576975 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline 0.9%
Description: compare the use of ketamine versus dexmedetomidine when used as perioperative infusion in obese patients undergoing laparoscopic bariatric surgery regarding their analgesic efficacy as well as any side effects or drawbacks (PONV and effects on consciousness) that might associate with their use.
Study NCT06464224 — intervention group
Intervention type: BEHAVIORAL
Intervention: low respiratory effort
Description: patients under respiratory effort lower than -1,5 cmH2O (P0,1) and/or -7 cmH2O (Pocc)
Study NCT06464224 — intervention group
Intervention type: BEHAVIORAL
Intervention: high respiratory effort
Description: patients under respiratory effort higher than -3,5 cmH2O (P0,1) and/or -15 cmH2O (Pocc)
Study NCT06514417 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: US-guided external oblique intercostal block
Description: After induction of general anesthesia, external oblique intercostal block will be performed (8) under ultrasonographic guidance with transportable ultrasound device ( Sonosite ,superficial probe ,14-15 MHz).~the patient will be positioned supine, and a linear ultrasound transducer will be placed in the sagittal plane between the midclavicular and anterior axillary lines at the level of sixth rib. 20 ml of bupivacaine 0.25% will be injected between the plane of the external oblique and the intercostal muscles. The drug will be injected after a negative aspiration.~The contralateral side block will be performed in a same manner.
Study NCT05719688 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical thrombectomy
Description: Treatment of ischemic stroke patients with Mechanical thrombectomy
Study NCT05719688 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical thrombectomy
Description: Treatment of ischemic stroke patients with Mechanical thrombectomy
Study NCT05567146 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental group
Description: It is planned to use the social media platform WhatsApp application to carry out the study. technique of gamification will have content in the form of points, ranking, penalties and rewards, which are the basic principles of gamification.~Studies have shown that these contents are effective techniques to increase the interest, encouragement, motivation and purpose of the participants.
Study NCT06008366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 7MW3711 for injection
Description: IV administration of 7MW3711, Q3W, 3 weeks a cycle
Study NCT06008366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 7MW3711 for injection
Description: IV administration of 7MW3711, the dosage regimen including dosage and dosing frequency for cohort expansion is conformed on basis of the data in part 1
Study NCT05445661 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: injectable poly-L-lactic acid
Description: Injectable biostimulant for volume loss
Study NCT05445661 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Normal Saline
Description: Sham Comparator
Study NCT05128968 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endotracheal intubation
Description: Endotracheal intubation is performed in simple head extension or sniffing position using a McGrath MAC videolaryngoscope.
Study NCT05178433 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Use baby moisturizers by NeoChine
Description: During continuous phototherapy, use skin basic care and protection in combination with baby moisturizing products, use the whole body twice a day, and the amount of each time is not less than 5 grams.
Study NCT00476983 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: saquinavir/ritonavir plus truvada
Description: SQV/r 1500/100 mg OD + Truvada OD for 2 years
Study NCT04721444 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Machine Learning Classification of parenchymal lung change cause
Description: Arms A \& B: Radiomics and deep-learning approaches will be used on patient's imaging to develop a feature vector that can distinguish parenchymal lung changes, e.g. infection from drug-toxicity.
Study NCT04721444 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Machine Learning Classification of recurrence and non-recurrence
Description: Arm C: Radiomics and deep-learning approaches will be used on patient's imaging to develop a risk-signature for recurrence of malignancy following radical treatment
Study NCT04849065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MNC (Mononuclear cells)
Description: * Intramuscular infusion of autologous BM CMN into the TA muscle of one of the lower limbs (experimental side)~* Intramuscular infusion of saline solution (placebo) in the TA muscle of the contralateral lower limb (control side)
Study NCT04849065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo / Saline
Description: - Intramuscular infusion of saline solution (placebo) in the TA muscle of the contralateral lower limb (control side)
Study NCT04849065 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo / Saline
Description: - Intramuscular infusion of saline solution (placebo) in the TA muscle of the contralateral lower limb (control side)
Study NCT05189886 — intervention group
Intervention type: PROCEDURE
Intervention: Double Balloon Valvuloplasty in TAVR
Description: The prospective phase will enroll patients planning to undergo TAVR, at the discretion of Drs. Wan and Fatemi, and if they meet all of the inclusion criteria and none of the exclusion criteria. All patients who provide consent will undergo the TAVR procedure where the valve will be double inflated. Echocardiogram results and procedure details will be collected as data. At the patient's 30-day follow-up clinic visit, as per standard of care, they will be re-evaluated with an echocardiogram. Details from that follow-up visit and the echocardiogram results will be collected as data. Prospective enrollment will begin upon IRB approval and we plan to continue enrollment until December 31, 2023, or once 200 participants are reached, whichever comes first.
Study NCT05962203 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Multi-factorial geriatric assessment, monitoring & management systems
Description: Multi-factorial geriatric assessment, monitoring \& management systems, e.g. community-based and home-based exercise programs, polypharmacy
Study NCT05503810 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social support
Description: Contact ones a week with Informal caregiver or peer support
Study NCT06361979 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-A1811
Description: SHR-A1811: intravenous
Study NCT06361979 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab:intravenous
Study NCT05387044 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: Patients with oligoprogressive NSCLC after first line treatment with immune checkpoint inhibitors will be treated with SBRT for all progressing lesions.
Study NCT04934410 — intervention group
Intervention type: DRUG
Intervention: Etomidate
Description: Use of etomidate during induction as decided by attending anesthesiologist
Study NCT04934410 — intervention group
Intervention type: DRUG
Intervention: Midazolam
Description: Use of midazolam during induction as decided by attending anesthesiologist
Study NCT04934410 — intervention group
Intervention type: DRUG
Intervention: Sevoflurane
Description: Use of sevoflurane during induction as decided by attending anesthesiologist
Study NCT06370130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine 0.2mg/kg
Description: Patients received 0.2 mg/kg of esketamine intravenously for 30 s，after 120 s of propofol and disappearance of the eyelash reflex, a laryngeal mask was inserted.~The test was performed using the sequential method. The initial dose of propofol was 2 mg/kg, which can be easily inserted into the LMA, and the propofol dose ratio of the adjacent patient was 0.9. If there was a positive reaction to the LMA insertion, the gradient was increased for the next patient; otherwise, the gradient was decreased, and the study was terminated after seven crossover inflection points.
Study NCT06370130 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Esketamine 0.3mg/kg
Description: Patients received 0.3 mg/kg of esketamine intravenously for 30 s，after 120 s of propofol and disappearance of the eyelash reflex, a laryngeal mask was inserted.~The test was performed using the sequential method. The initial dose of propofol was 2 mg/kg, which can be easily inserted into the LMA, and the propofol dose ratio of the adjacent patient was 0.9. If there was a positive reaction to the LMA insertion, the gradient was increased for the next patient; otherwise, the gradient was decreased, and the study was terminated after seven crossover inflection points.
Study NCT04735757 — intervention group
Intervention type: OTHER
Intervention: Contrast-enhanced MRI
Description: Contrast-enhanced MRI
Study NCT04735757 — intervention group
Intervention type: OTHER
Intervention: Measurement of respiratory muscle force
Description: Measurement of the maximum inspiratory and expiratory pressure.
Study NCT06351436 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: The mindfulness-based intervention will last for three months, with 6-8 weekly sessions lasting 1.5 hours each. Participants will attend the sessions in a group format, and the sessions will be administered by registered social worker who are specialized in counseling. The intervention is delivered using an immersive virtual reality cave system. The intervention content is designed by a registered clinical psychologist accredited for delivering mindfulness-based intervention and nurses who are experienced in mindfulness training. To ensure protocol adherence, the social workers administering the intervention will receive close supervision from the clinical psychologist. Weekly meetings will be held to discuss and resolve any difficulties or challenges encountered by the social workers.
Study NCT05974436 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood and dialysate sampling
Description: Blood is sampled from the inlet and outlet dialyzer bloodline at 5min after dialysis start.~Spent dialysate is sampled from the outlet dialysate line at 5, 30, 90 and 240min after dialysis start.~Blood and dialysate samples are analysed for different uremic toxins. Dialysis efficiency is calculated from the analysed toxin concentrations.
Study NCT06151314 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental implants.
Description: 5 conventional implants measuring from 4 to 5 mm in width and 7 to 10mm in length according to the bone width were inserted in the mandible from right premolar area to left premolar area
Study NCT06408948 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]SHR7280
Description: Patients will receive single dose of orally \[14C\]SHR7280 on Day 1.
Study NCT05201196 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Targeted muscle stretching and Strengthening (flexors, Extensors, abductors, internal and external rotators, of Shoulder, Elbow, forearm (supination \& pronation) and hand 10 repetitions×1 set, 4 days/ week. Transcutaneous Electrical nerve Stimulation for 10-20 min, 4 days/ week. Total of 16 sessions were given each consisting of 45 mins.
Study NCT05201196 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Task Oriented Training
Description: Experimental group was given Task oriented protocol including activities such as Table-top polishing, Arm cradling, Reach forward and pick-up or touch an object, Reached sideway to pick-up an object and transferring it to a table in front, Pouring~½ cup of water from a measuring pot into wide mouth glass held in opposite hand, Picking up pen from thumb and first two fingers, lifting a basket and placing it on the table 10 repetitions×1 set for each activity, 4-5days/week. Total of 16 sessions were given each consisting of 45 mins
Study NCT06199063 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self-Streching Exercises
Description: The participants in the SSE group; received 1 session SSE with 10 repetitions, about 30 min. The assessments were applied before and after the session.
Study NCT06199063 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Post-Isometric Relaxation Exercises
Description: The participants in the PIRE group; received 1 session PIRE with 10 repetitions, about 30 min. The assessments were applied before and after the session.
Study NCT06199063 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reciprocal-Inhibiton Exercises
Description: The participants in the RIE group; received 1 session RIE with 10 repetitions, about 30 min. The assessments were applied before and after the session.
Study NCT06414720 — intervention group
Intervention type: DRUG
Intervention: Dienogest 2 MG
Description: The patients will be started on progestin therapy after a saliva sample is collected from them for miRNA analysis.
Study NCT04810286 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 3d-Printing Myofunctional Appliance
Description: To evaluate soft- and hard-tissue changes Class II division 1 tchildren with a prefabricated myofunctional appliance versus a 3D-printed myofunctional appliance.
Study NCT04810286 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 3d-Printing Myofunctional Appliance
Description: To evaluate soft- and hard-tissue changes Class II division 1 tchildren with a prefabricated myofunctional appliance versus a 3D-printed myofunctional appliance.
Study NCT05747209 — intervention group
Intervention type: OTHER
Intervention: Observation of Exercise Program Adherence
Description: Observation of a monitored group exercise regimen utilizing standard of care high-load resistance training and functional exercises with compound movements under close supervision and with the goal of improving functional mobility, body composition, and strength after cancer treatment to study adherence and attendance to the exercise program.
Study NCT04786990 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPN-812
Description: Viloxazine extended-release capsule
Study NCT06446167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercises
Description: All groups received a regimen of daily exercises, including stretches for the plantar fascia and Achilles tendon, and strengthening exercises for the calf muscles and foot intrinsic muscles. Each type of exercise was demonstrated to the participants by the same physiotherapist at the beginning of the treatment process, to be performed twice a day with 10 repetitions each time.
Study NCT06446167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MLS Laser Treatment
Description: The MLS Laser applied to the treatment group was administered using an ASA brand Mphi model device. Patients in the Laser group were positioned in a prone position. Treatment was applied continuously for 7 minutes along the plantar fascia, sole of the foot, heel area, and Achilles tendon in accordance with the plantar fasciitis treatment program on the device, at a dose of 1.73 J/cm2 and a frequency of 700 Hz. A treatment program was established with 3 sessions per week, totaling 10 sessions
Study NCT06446167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ESWT treatment
Description: The treatment group was administered with the Swiss DolorClast Master ESWT device, which produces radial shock waves. Patients in the ESWT group were positioned in a prone position. The most painful point in the heel area was identified through palpation. Gel was applied to this area, followed by the surrounding soft tissues, towards the plantar fascia and the attachment area of the Achilles tendon at the dorsal aspect of the heel. Radial ESWT treatment was applied at a frequency of 10 Hz, pressure of 2.5 bars, and 2000 impulses per session, once a week for a total of 4 sessions
Study NCT04757376 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CT-P41
Description: 60 mg/mL single dose, Solution for injection in PFS
Study NCT04757376 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: US-licensed Prolia
Description: 60 mg/mL single dose, Solution for injection in PFS
Study NCT03621397 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: brainHQ by Posit Science
Description: This is an online cognitive training program. It consists of 29 online exercises that work out attention, brain speed, memory, people skills, navigation, and intelligence. The current study will focus on the following exercises: attention, brain speed (e.g., processing speed), executive function, and memory.
Study NCT05627791 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin vaginal gel that have oxytocin 400IU/1ml of gel, base gel contained HPMC 4,000 cps, 5% propylene glycol USP, 0.08% methylparaben, sterile water for irrigation and 0.02% propylparaben then adjusted pH by Lactic acid and sodium hydroxide keep pH 3.5-4.0
Study NCT05627791 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo gel that have base gel contained HPMC 4,000 cps, 5% propylene glycol USP, 0.08% methylparaben, sterile water for irrigation and 0.02% propylparaben then adjusted pH by Lactic acid and sodium hydroxide keep pH 3.5-4.0 without oxytocin