AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06701084 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genomic Sequencing
Description: Genomic sequencing data will be comprehensively analyzed for pathogenic variants that explain the participants epilepsy.
Study NCT06701513 — intervention group
Intervention type: DRUG
Intervention: Deucravacitinib
Description: As prescribed by treating clinician
Study NCT06701916 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention group.
Description: The intervention will be carried out by a multidisciplinary team composed of nurses, doctors, social workers, and psychologists from each hospital. Through this intervention, a narrative from the patients will be obtained regarding their goals, desires, capabilities, and resources related to their health situation. A health plan will be jointly created, reflecting both short- and long-term objectives, identifying the resources available to the person and within their immediate environment, and outlining how they want and expect to receive support from healthcare professionals.
Study NCT06701916 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care for the outpatient management of Chronic Heart Failure.
Study NCT06357208 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing Control and Retention
Description: 4 appointments with training of Breathing Control and Retention
Study NCT04909177 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Smartphone application (app) in combination with headset
Description: The intervention oVRcome is self-help VRET for specific phobia, that is delivered through a smartphone application (app) in combination with headset that holds the smartphone and uses 360º video. oVRcome includes 6 modules of psychoeducation, relaxation, mindfulness, cognitive techniques, exposure through VR, and a relapse prevention module which are aimed to be completed weekly.
Study NCT05927194 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Using the Connect
Description: Using the Connect (UTC) is an innovative, game-based intervention for youth to develop skills in adulthood preparation topics such as communication, decision making and accessing information.
Study NCT06507059 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cabotegravir/rilpivirine (600mg/ 900mg)
Description: Immediate switch from oral antiretroviral to long-acting injectables
Study NCT04744961 — intervention group
Intervention type: OTHER
Intervention: SCAR-Q survey
Description: Telephone survey
Study NCT06507059 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antiretroviral Combinations
Description: Standard all-oral antiretroviral combinations
Study NCT05669859 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The rehabilitation program designed in our study was based on the development of core muscle control and dynamic stabilization of the spine, which is generally required by patients. All exercises were combined with controlled breathing, focusing on the mobility of the extremities and the activity of multiple muscle groups.~Our program created in this direction will start with face-to-face patient education; For 8 weeks, will be carried out remotely online under the supervision of a physiotherapist.On non-telerehabilitation days, they will be asked to keep an exercise diary, instructed to practice the exercise approach presented in sessions at home daily in 20-minute periods. The exercise diary will be checked during online sessions.
Study NCT04791436 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Gustatory and olfactory function test
Description: The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.
Study NCT04791436 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Molecular assessment of saliva
Description: Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.
Study NCT06157866 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: During the treatment sessions the acupuncturist will insert needles in several locations aimed to reduce the patient's fibromyalgia pain. A low-amplitude, sub-sensory electrical current will be activated by the acupuncturist.
Study NCT06157866 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Electroacupuncture
Description: During the treatment sessions the acupuncturist will insert needles in several locations aimed to reduce the patient's fibromyalgia pain. A low-amplitude, sub-sensory electrical current will be activated by the acupuncturist.
Study NCT06157866 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Training
Description: Cognitive training with a pain specialist.
Study NCT06157866 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education Training
Description: Education training with a pain specialist.
Study NCT05666349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: 100 mg, 200 mg, or 300mg oral niraparib once daily.
Study NCT05666349 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Re-irradiation (re-RT)
Description: Intensity modulated radiotherapy (IMRT)-based re-RT for a total dose of 35 Gy in 10 daily fractions.
Study NCT04766463 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection
Description: SHR8554 Injection; high dose
Study NCT04766463 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR8554 Injection
Description: SHR8554 Injection; low dose
Study NCT04766463 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline Solution
Study NCT04766463 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Morphine
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Undergo standard of care diet
Study NCT06391099 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and stool sample collection
Study NCT06391099 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Under CT
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary Intervention
Description: Undergo ketogenic diet
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Activity
Description: Receive coaching support
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Glucose Measurement
Description: Undergo blood glucose testing
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketone Measurement
Description: Undergo ketone measurement
Study NCT06391099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04648930 — intervention group
Intervention type: DRUG
Intervention: Xolair
Description: There was no treatment allocation. Patients administered Xolair by prescription that started before inclusion of the patient into the study were enrolled.
Study NCT05639270 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: use of an auricular electrode
Description: Use of the auricular electrode throughout the duration of the study (30minutes/day) combined with assessment of pain, tolerance, vagal tone.
Study NCT06290856 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multiplex PCR-test for circulating tumor DNA
Description: All recruited patients will be tested for
Study NCT05216536 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT06006416 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fenugreek Fibre
Description: Daily dose of 2 x 10g per day with/in food
Study NCT04733157 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic acid injection
Description: Tranexamic 1g administered intravenously at the onset of skin incision at caesarean section
Study NCT04733157 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline placebo
Description: 10ml of normal saline will be administered intravenously at onset of skin incision at caesarean section to the placebo group
Study NCT06664749 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three stair position pillow group
Description: Preterm infants were monitored with three stair position pillows.
Study NCT06664749 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Positioning material group
Description: Preterm infants were monitored with positioning material pillows.
Study NCT05714579 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcatheter Aortic Valve Implantation
Description: The TAVI procedure is performed transfemorally under local anesthesia most often, or more rarely under general anesthesia via the subclavian or transaortic route. Identification is carried out under fluoroscopy in the cardiac catheterization room. The crossing of the aortic valve allows the establishment of a guide at the bottom of the left ventricle. Aortic valve predilation can be performed. The tightness of the device is checked by an aortography. Sometimes, post-dilation of the implanted bioprosthesis proves necessary, particularly in the event of under-deployment or significant para-prosthetic leakage.~The duration of the intervention is approximately 1 hour.
Study NCT05510323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone
Description: RAS blockade as much as tolerated or allowed
Study NCT05510323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prednisolone plus Cyclophosphamide
Description: RAS blockade as much as tolerated or allowed
Study NCT05049161 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 18 mg/kg
Description: temelimab 18 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)
Study NCT05049161 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 36mg/kg
Description: temelimab 36 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)
Study NCT05049161 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temelimab 54 mg/kg
Description: temelimab 54 mg/kg will be given as monthly (4-weekly) intravenous (IV) infusions over 48 weeks (12 administrations in total)
Study NCT04944485 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: (FIT SA F03, SHOFU, USA)
Description: Self adhesive giomer containing nanohybrid flowable composite
Study NCT04944485 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: (Neo Spectra™ ST, Dentsply, Sirona, USA)
Description: Conventional technique using putty nanohybrid resin composite
Study NCT04936568 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Palliative Care Referral System - PCRS
Description: Implementation of a system to help oncologists to identify criteria for referring patients to specialized outpatient palliative care (Palliative Care Referral System - PCRS)
Study NCT05477940 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Absorbable zinc alloy drug eluting coronary stent system
Description: Absorbable zinc alloy drug eluting coronary stent system (hereinafter referred to as stent system) consists of delivery system and drug stent (hereinafter referred to as stent) pressed on the balloon end of the delivery system
Study NCT05831475 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intergenerational Virtual Paired Exercise
Description: Participants will be paired with someone older/ younger and will engage in exercise videos with the ability to simultaneously video chat with their partner while exercising. Participants will log on with their partner twice a week for 8 weeks.
Study NCT05831475 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer Virtual Paired Exercise
Description: Participants will be paired with someone of the same age group and will engage in exercise videos with the ability to simultaneously video chat with their partner while exercising. Participants will log on with their partner twice a week for 8 weeks.
Study NCT06642662 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Somascan 5.0
Description: This observational study will test patient plasma using the SomaScan platform, a highly multiplexed proteomic tool that uses SOMAmers (Slow Off-rate Modified Aptamers) to bind with high specificity and affinity to preselected proteins to quantify levels. SomaScan v5.0 quantifies 10,778 clinically relevant human proteins, with several thousand proteins linked to inflammation and immune system functions, across a wide range of concentrations (>10 logs) with high sensitivity (\<1 pg/mL) and reproducibility (median coefficient of variation \< 5%). Individual protein concentrations are transformed into a corresponding SOMAmer concentration and quantified using a DNA microarray read-out.
Study NCT05636475 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual hand massage after laparoscopic cholecystectomy surgery
Description: Manual hand massage is applied to a group of patients at 0, 4 and 8 hours after the patient returns from laparoscopic cholecystectomy surgery. It is applied to each hand for ten minutes.
Study NCT05636475 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Machine-based hand massage after laparoscopic cholecystectomy surgery
Description: Machine-based hand massage is applied to a group of patients at 0, 4 and 8 hours after the patient returns from laparoscopic cholecystectomy surgery. It is applied to each hand for ten minutes.
Study NCT06319599 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine therapy
Description: During the treatment, All the participants are provided with the routine therapy, which included routine rehabilitation, cognitive training.
Study NCT06319599 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Routine therapy
Description: During the treatment, All the participants are provided with the routine therapy, which included routine rehabilitation, cognitive training.
Study NCT05610215 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hybrid ablation
Description: simultaneous thoracoscopic epicardial and catheter endocardial ablation
Study NCT05610215 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: catheter ablation
Description: catheter endocardial ablation
Study NCT06319599 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.
Study NCT06319599 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine hydrochloride
Description: Based on the invention above, the patients in the experimental group were provided with Stellate ganglion block , using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g). Once a day, totally 10 days.
Study NCT06319599 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo injection
Description: The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.
Study NCT06346301 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Imagery rescripting
Description: In Imagery Rescripting participants imagine a different sequence of events based on missed emotional needs and rescript until needs are fulfilled. Duration of sessions is up to 90 minutes.
Study NCT05112393 — intervention group
Intervention type: OTHER
Intervention: Development of new estimating Glomerular Filtration Rate (eGFR) equation
Description: Development Cohort:~A new estimating Glomerular Filtration Rate(eGFR) equation will be developed by using a nonlinear regression model utilizing a generalized least squares algorithm.
Study NCT05112393 — intervention group
Intervention type: OTHER
Intervention: Validation of new estimating Glomerular Filtration Rate (eGFR) equation
Description: Validation Cohort:~Internal validation will be performed by comparing bias, precision and accuracy of the new equations and the other established equations to the measured GFR.
Study NCT05124639 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group self-management support program for anxiety disorders
Description: The group SMS manualized program for anxiety disorders (https://monrelief.ca) aims at improving self-management capabilities through weekly 2.5-hours sessions with 10-15 patients over a 10-week period.This trial will focus solely on the virtual format of the program. The SMS program covers the following themes: getting to know your anxiety; building self-awareness; reconsidering your lifestyle habits; adopting a problem-solving method; avoidance and exposure; acceptance and committed action; seeing things differently; managing your emotions; receiving support from others; and consolidating your toolkit.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 1.5 mg/kg
Description: 1.5 mg/kg MAM01 will be administered via IV route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered via IV route.
Study NCT06390280 — intervention group
Intervention type: PROCEDURE
Intervention: intraoperative Fraction of Inspired Oxygen
Description: Group I intraoperative Fraction of Inspired Oxygen 30%, Group II intraoperative Fraction of Inspired Oxygen 80% applied group.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 5 mg/kg
Description: 5 mg/kg MAM01 will be administered via SC route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 10 mg/kg
Description: 10 mg/kg MAM01 will be administered via IV route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 40 mg/kg
Description: 40 mg/kg MAM01 will be administered via IV route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 450 mg
Description: MAM01 will be administered via SC route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered via SC route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 5 mg/kg
Description: 5 mg/kg MAM01 will be administered via IV route.
Study NCT05891236 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: No drug or placebo will be administered.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 600 mg
Description: MAM01 will be administered via SC route.
Study NCT05891236 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MAM01 900 mg
Description: MAM01 will be administered via SC route.
Study NCT06416748 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Minimally invasive simple hysterectomy
Description: Patients with SHAPE inclusion criteria (FIGO 2018 stage IA2 and IB1 up to 2 cm, with limited stromal invasion: \&amp;amp;lt; 10 mm on LEEP/cone and \&amp;amp;lt; 50% depth on imaging) should undergo conization with surgical margins free from invasive disease or conization with involved surgical margins followed by MRI scan or expert ultrasound scan showing no residual disease. In case of residual disease at post conization imaging still fitting inclusion criteria, another conization is recommended. After these steps minimally invasive (laparoscopy or robotic) simple hysterectomy is performed with sentinel lymph node biopsy algorithm. Adjuvant therapy is given only in case of positive surgical margins, metastatic lymph nodes, and extensive LVSI with depth of stromal infiltration over 2/3.
Study NCT05288621 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: electroacupuncture
Description: For'four sacral points'group, Hua Tuo brand disposable acupuncture needles (size 0.40 × 100mm) and electronic needle therapy instrument SDZ-IIB will be used.Bilateral BL30 and BL35, were selected as acupoints protocol.~'Four sacral points'group consists of 8 sessions over an 4-week period after baseline(2 sessions in each week), each for 30minutes. The electroacupuncture will be set at a frequency of 2.0 Hz, continuous wave, a moderate intensity the patient can tolerate and 30 min during each treatment.
Study NCT05288621 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: For'four sacral points'group, Hua Tuo brand disposable acupuncture needles (size 0.40 × 100mm) and electronic needle therapy instrument SDZ-IIB will be used.Bilateral BL30 and BL35, were selected as acupoints protocol.~'Four sacral points'group consists of 8 sessions over an 4-week period after baseline(2 sessions in each week), each for 30minutes. The electroacupuncture will be set at a frequency of 2.0 Hz, continuous wave, a moderate intensity the patient can tolerate and 30 min during each treatment.