AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06089980 — intervention group
Intervention type: BEHAVIORAL
Intervention: Effects from acute kratom exposure
Description: Participants who regularly use commercial Kratom products will orally consume a known quantity of kratom under direct observation on first study day; following this, participants will stop kratom use for approximately 2 nights and 2.5 days for the duration of the study.
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Golcadomide
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rituximab
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Cyclophosphamide
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Doxorubicin
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Description: Specified dose on specified days
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vincristine
Description: Specified dose on specified days
Study NCT05016375 — intervention group
Intervention type: OTHER
Intervention: Interview
Description: Interview with individuals with T2DM
Study NCT05936814 — intervention group
Intervention type: PROCEDURE
Intervention: total knee arthroplasty
Description: cemented bicondylar PCL substituting total knee replacement
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Specified dose on specified days
Study NCT05176717 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QR-421a
Description: RNA antisense oligonucleotide for intravitreal injection
Study NCT05176717 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham-procedure
Description: Sham-procedure (no experimental drug administered)
Study NCT05263518 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cataract surgery with AcrySof IQ IOL implantation.
Description: Patients in this study will receive cataract surgery with AcrySof IQ IOL implantation.
Study NCT05263518 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cataract surgery with TECNIS toric IOL implantation.
Description: Patients in this study will receive cataract surgery with TECNIS toric IOL implantation.
Study NCT06612489 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: biofeedback based dynamic-difficulty game
Description: A biofeedback based dynamic-difficulty serious game rooted in distraction therapy.
Study NCT06612489 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: fixed difficulty game
Description: A fixed difficulty serious game rooted in distraction therapy.
Study NCT06612957 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Repair of uterine cicatricial diverticulum
Description: Cut off the uterine cicatricial diverticular tissue in the lower portion of the uterus, and restore normal uterine muscle tissue.
Study NCT06611462 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation (the STRONG programme)
Description: Participants screened positive for one or more SNAP factors and randomised to the intervention group will receive an individualised plan for prehabilitation of their specific SNAP factors.
Study NCT06611670 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cataract surgery with Active Sentry
Description: Surgical instrument that detects changes in intraocular pressure and allows rapid feedback to stabilize pressure during cataract surgery.
Study NCT06611670 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional cataract surgery
Description: Cataract surgery performed with high intraocular pressures
Study NCT06613152 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-IT201 Injection
Description: Adoptive transfer of 5x10\^9-4x10\^10 autologous TIL to patients i.v. in 30-60 minutes.
Study NCT06612931 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dual-lumen catheter-guided mini-forceps biopsy is performed first
Description: In ERCP procedures, catheter-guided mini-forceps biopsy is performed before biliary brush cytology.
Study NCT06612931 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biliary brush cytology with vacuum aspiration is performed first
Description: In ERCP procedures, biliary brush cytology with vacuum aspiration is performed before dilation catheter-guided mini-forceps biopsy.
Study NCT04888494 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Magnetic Stimulation
Description: For the brain stimulation the investigators will use Repetitive Transcranial Magnetic stimulation (rTMS). Different stimulation conditions (hippocampal or sham) will be delivered in each round of stimulation (5 days). Repetitive TMS will be applied at 100% resting motor threshold intensity, 20 Hz pulse trains separated by 28-s inter-train intervals (\~20 minutes for the entire daily stimulation session). Stimulation parameters will be identical in both groups
Study NCT04888494 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham rTMS
Description: Sham rTMS
Study NCT04052321 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D optical surface scan
Description: A 3D optical surface scan is acquired utilizing a handheld 3D scanner. Such a scanner is comparable to an ordinary photo camera, however, it also records depth.
Study NCT06356129 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Prednisone
Description: Specified dose on specified days
Study NCT05592418 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rintatolimod
Description: 100 to 400 mg twice weekly
Study NCT05592418 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo / Normal Saline
Description: 40 to 160 mL twice weekly
Study NCT06333392 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total underwater colonoscopy
Description: one grooup will be randomized to receive a total underwater colonoscopy
Study NCT06333392 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional colonoscopy
Description: one group will be randomized to undergo a conventional colonoscopy with CO2 withdrawal
Study NCT04816461 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amodiaquine Sulfadoxine-Pyrimethamin administration
Description: SMC treatment
Study NCT04816461 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amodiaquine Sulfadoxine-Pyrimethamin administration
Description: SMC treatment
Study NCT04816461 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dihydroartemisinin-Piperaquine
Description: Roommates treatment if they are positive to malaria
Study NCT04816461 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Standard HRP2-RDT
Description: Roommates screening with standard HRP2-RDT
Study NCT06220643 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: resistance exercise
Description: Progressive resistance exercise for 12 weeks
Study NCT06220643 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: triamcinolone acetonide plus lidocaine
Description: 40mg triamcinolone acetonide 1cc plus 2cc lidocaine (1%)
Study NCT06220643 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: triamcinolone acetonide plus lidocaine
Description: 40mg triamcinolone acetonide 1cc plus 2cc lidocaine (1%)
Study NCT05044793 — intervention group
Intervention type: DEVICE
Intervention: OMNI® Surgical System
Description: The OMNI® Surgical System is indicated for canaloplasty (microcatheterization and transluminal viscodilation of Schlemm's canal) followed by trabeculotomy (cutting of trabecular meshwork) to reduce intraocular pressure in adult patients with primary open-angle glaucoma.
Study NCT05018585 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®
Description: Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®
Study NCT05018585 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Colecalciferol 2000 IU
Description: Colecalciferol (vitamin D3) 2000 IU (equivalent to 50 microgram vitamin D3).
Study NCT05018585 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Colecalciferol 2000 IU
Description: Colecalciferol (vitamin D3) 2000 IU (equivalent to 50 microgram vitamin D3).
Study NCT05018585 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for Diamyd, Alhydrogel® only
Study NCT06390995 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-853
Description: TAK-853 intravenous injection
Study NCT06425198 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986278
Description: Specified dose on specified days
Study NCT05731427 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pseudomonas aeruginosa colonization infection
Description: With or without airway Pseudomonas aeruginosa colonization infection
Study NCT05731427 — intervention group
Intervention type: DRUG
Intervention: Macrolides
Description: Before or after 6 months of treatment with macrolides for patients with bronchiectasis
Study NCT06542081 — intervention group
Intervention type: BEHAVIORAL
Intervention: Descriptive information form, psychological resilience scale and disaster preparedness scale were completed by the parents of hearing impaired children.
Description: Descriptive information form, psychological resilience scale and disaster preparedness scale were completed by the parents of hearing impaired children.
Study NCT05307861 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pancreatic duct stenting with plastic stent
Description: Plastic pancreatic duct stent placement (5fr x 4 cm) for patients in need of pancreatic duct stenting during ERCP.
Study NCT05307861 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pancreatic duct stenting with Biodegradable Stent
Description: Biodegradable pancreatic duct stent placement (6fr x 4 cm or 6fr x 4 cm) for patients in need of pancreatic duct stenting during ERCP.
Study NCT04857619 — intervention group
Intervention type: OTHER
Intervention: None (Observational study)
Description: The data on different types of treatment received by the patients, socio-demographics, and clinico-pathological characteristics and healthcare resource utilisation will be extracted from patients' medical records (both alive and deceased).
Study NCT04808089 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Lung App. of mobile phone+ezOxygen mobile spirometry
Description: Subjects can get reminder to use inhaler on schedule, input ACT score to evaluate the asthma control, get education materials about asthma and operate spirometer to access lung function outside of hospital.~The physicians can get the information about control status, lung function, adherence of controller and usage of reliver of patients between each clinical visit, if patients following the instruction of Health Lung.
Study NCT04808089 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: The research assistant assess/ teach inhaler technique, offering advice on adherence, delivering patient self-management asthma action plan and education the meaning of asthma control accessed by ACT.
Study NCT04867525 — intervention group
Intervention type: OTHER
Intervention: Physician's choice according to patient's needs.
Description: Routine care as per site standard.
Study NCT05262621 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: progressive muscle relaxation
Description: Practice muscle relaxation for 20 minutes once/a day
Study NCT05262621 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Listening to relaxing music once/day
Description: Right after practising progressive muscle relaxation, the participants will listen to relaxing music for 20 minutes
Study NCT05361278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chlorhexidine solution
Description: * Irrigate the root canal with 1 ml of 2% CHx solution between each file 1 mm from the apical foramen by using a 27-gauge irrigation needle.~* Irrigate the root canal with 3 ml of the solution after using the last file.~* Irrigation with 3 ml of 0.5% Tween 80 and 0.07 % lecithin to remove residual chlorhexidine solution.~* Drying the canal with paper points (placing a 20 size paper point for 60 seconds in each canal) to take the bacterial smear.~* Follow-up of endodontic treatment procedures for the treated tooth.
Study NCT05361278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activated chlorhexidine solution
Description: * Irrigate the root canal with 1 ml of 2% CHx solution between each file 1 mm from the apical foramen by using a 27-gauge irrigation needle with activation using an ultrasonic irrigation head.~* Irrigate the root canal with 3 ml of the solution after using the last file with activation using an ultrasonic irrigation head.~* Irrigation with 3 ml of 0.5% Tween 80 and 0.07 % lecithin to remove residual chlorhexidine solution.~* Drying the canal with paper points (placing a 20 size paper point for 60 seconds in each canal) to take the bacterial smear.~* Follow-up of endodontic treatment procedures for the treated tooth.
Study NCT05361278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chlorhexidine gel
Description: * Irrigate the root canal with 1 ml of 2% CHx gel between each file 1 mm from the apical foramen by using a 27-gauge irrigation needle.~* Irrigate the root canal with 3 ml of the gel after using the last file.~* Irrigation with 3 ml of 0.5% Tween 80 and 0.07 % lecithin to remove residual chlorhexidine gel.~* Drying the canal with paper points (placing a 20 size paper point for 60 seconds in each canal) to take the bacterial smear.~* Follow-up of endodontic treatment procedures for the treated tooth.
Study NCT05361278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activated chlorhexidine gel
Description: * Irrigate the root canal with 1 ml of 2% CHx gel between each file 1 mm from the apical foramen by using a 27-gauge irrigation needle with activation using an ultrasonic irrigation head.~* Irrigate the root canal with 3 ml of the gel after using the last file with activation using an ultrasonic irrigation head.~* Irrigation with 3 ml of 0.5% Tween 80 and 0.07 % lecithin to remove residual chlorhexidine gel.~* Drying the canal with paper points (placing a 20 size paper point for 60 seconds in each canal) to take the bacterial smear.~* Follow-up of endodontic treatment procedures for the treated tooth.
Study NCT05361278 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Sodium hypochlorite solution
Description: * Irrigate the root canal with 1 ml of 5.25% sodium hypochlorite solution between each file 1 mm from the apical foramen by using a 27-gauge irrigation needle.~* Irrigate the root canal with 3 ml of the solution after using the last file.~* Irrigating the canal with 3 ml of 5% sodium thiosulfate solution to remove residual of sodium hypochlorite.~* Drying the canal with paper points (placing a 20 size paper point for 60 seconds in each canal) to take the bacterial smear.~* Follow-up of endodontic treatment procedures for the treated tooth.
Study NCT05226910 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS and intensive therapies
Description: This intervention will consist in the combination of tDCS with CIMT (30 hours) and then with BIT (3 hours and 45 minutes)
Study NCT05226910 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham and intensive therapies
Description: This intervention will consist in the combination of sham tDCS with CIMT (30 hours) and then with BIT (3 hours and 45 minutes)
Study NCT05095194 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cataract surgery with IOL implantation and with/without capsular tension ring implatation
Description: Patients in this study will receive cataract surgery with IOL implantation and capsular tension ring implantation or cataract surgery with IOL implantation
Study NCT05960175 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: New telemonitoring approach using 2 connected devices : Scanwatch connected watch + Asten&masanté application
Description: The home healthcare provider will monitor the treatment remotely and make home visits, as in the control group. However, in the case of technical alerts concerning CPAP treatment (problems with observance, leaks, residual apneas), the provider will send the patient a notification via the mobile application in order to provide advice/instructions so that the patient can resolve the alert independently. The provider will monitor the resolution of alerts remotely and may contact the patient by telephone or come to your home if necessary.~If the connected watch detects an abnormal heart rhythm at night, the patient receives a notification and can undergo an electrocardiogram.
Study NCT05545137 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pivmecillinam hydrochloride tablets
Description: 400mg tablet
Study NCT05545137 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fosfomycin Tromethamine Granules
Description: 3g/pack
Study NCT06210776 — intervention group
Intervention type: DRUG
Intervention: Trastuzumab deruxtecan
Description: Intravenous infusion
Study NCT06135389 — intervention group
Intervention type: BIOLOGICAL
Intervention: Titration of paracetamol and its metabolites - scheme1
Description: 15 to 20 minutes and 1 to 2 hours after first perfusion and before second perfusion/administration of paracetamol
Study NCT06135389 — intervention group
Intervention type: BIOLOGICAL
Intervention: Titration of paracetamol and its metabolites - scheme 2
Description: 30 to 40' after first perfusion and before second perfusion/administration of paracetamol (residual concentration)
Study NCT03590821 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin 81 mg
Description: timed administration of aspirin in the evening
Study NCT06480019 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Interpersonal psychotherapy
Description: Interpersonal psychotherapy is a first-line treatment and can also be used for the prevention of depression.
Study NCT03590821 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Celecoxib 200mg capsule
Description: daily administration of celecoxib
Study NCT05028634 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tetanus, diphtheria, and acellular pertussis vaccine
Description: Tdap
Study NCT05028634 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pneumococcal polysaccharide vaccine
Description: PPSV23
Study NCT05851638 — intervention group
Intervention type: DEVICE
Intervention: Lung Oxygen measurement with GASMAS system
Description: A specially designed light source probe (2x2cm size) with 2x incorporated laser sources and a detector probe (2x2cm size) will be attached to the torso of the infant in a total of 10 locations to measure lung oxygen.
Study NCT05028634 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Seasonal influenza vaccine
Description: Seasonal influenza vaccine
Study NCT05027438 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy for Insomnia
Description: A multimodal psychotherapy that may include stimulus control, sleep restriction, cognitive therapy, psychoeducation, and relaxation strategies
Study NCT05027438 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Deprescribing
Description: The reduction or withdrawal of a medication, through gradual dose reduction, managed by a healthcare professional that aims to reduce harm and improve outcomes
Study NCT05041803 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTP-543
Description: Twice daily dosing
Study NCT05349019 — intervention group
Intervention type: OTHER
Intervention: Observational
Description: This is an observational study to investigate the natural history of G2019S LRRK2 PD using traditional and digital methodology (digital phenotyping). Study conduct will be decentralized (at home as much as possible) consisting of two parts: Part A with Healthy Volunteers (HV) participants and Part B in patients with G2019S LRRK2 PD.
Study NCT05930171 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound guided L-ESPB and PENG block using Bupivacaine
Description: Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
Study NCT05930171 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Postoperative conventional analgesia in form of Acetaminophen
Description: Postoperative conventional analgesia in form of acetaminophen 15 mg/kg/6hrs
Study NCT04241913 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mom Power Intervention
Description: Mom Power is a 10-week therapeutic intervention for at-risk families that incorporates elements of several evidence based practices. It combines didactic material with mindbody self-care skills and in vivo practice to improve the quality of attachment between parent and child, and to reduce the psychopathology of at-risk parents. The child team component provides each child with one-on-one care focusing on meeting the child's social-emotional needs and providing attachment-related experiences within a developmental framework.
Study NCT06045000 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DC-806
Description: Oral tablets