AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05694247 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CorNeat KPro
Description: The optical component of the CorNeat KPro will be implanted into a circular disc of the cornea (as performed in standard penetrating keratoplasty surgery) and the skirt component will be embedded under a 360º conjunctival flap.
Study NCT06455033 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Manual Diaphragm Release Technique
Description: The participant will assume a supine position with relaxed limbs. The therapist should position themselves at the head of the participant and make manual contact with the pisiform, hypothenar region, and the last three fingers on both sides, underneath the seventh to tenth rib costal cartilages. The therapist's forearms should be aligned towards the participant's shoulders. During the inspiratory phase, the therapist gently pulled the points of contact with both hands in the direction of the head and slightly laterally, accompanying the elevation of the ribs. During exhalation, the therapist deepens their contact towards the inner costal margin while maintaining resistance. As the respiratory cycles continues, the therapist progressively increases the depth of their contact within the costal margin.
Study NCT06455033 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breathing Exercise
Description: Sit up straight in a chair lengthen the distance between your navel and sternum. Keep your shoulders relax.~Keep the pelvis in neutral position (Sit on your sitting bones). Place your hands at either side of your lower ribs. Breath in slowly through your nose. As you inhale feel your ribs expanding outwards and upwards. During inhalation is generated expansion of the trunk in three directions front , sides and back.~Breath out from your nose. As you exhale feel your lower ribs moving inwards.
Study NCT05471609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: levodopa/carbidopa oral formulation A
Description: Outer sachet 100mg CD/100mg LD and inner sachet 0mg CD /300mg LD
Study NCT05471609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: levodopa/carbidopa oral formulation B
Description: Outer sachet 100mg CD/0mg LD and inner sachet 0mg CD /400mg LD
Study NCT05471609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: levodopa/carbidopa oral formulation C
Description: Outer sachet 50mg CD/200mg LD and inner sachet 50mg CD /200mg LD
Study NCT05363995 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: i-Sleep & BioClock Intervention
Description: The 'i-Sleep \& BioClock' intervention aims at improving sleep and the biological clock among university students. It is incorporates evidence-based techniques such as cognitive behavioural therapy for insomnia (CBTi). The intervention has a duration of 5 weeks and consists of five modules:~1. psychoeducation on insomnia, sleep hygiene and the biological clock,~2. stimulus control and sleep restriction therapy,~3. worrying and relaxation exercises,~4. cognitive therapy to change dysfunctional thoughts about sleep, and~5. summary module, relapse prevention, and plan for the future.~The intervention is supported by e-coaches who give personalized written feedback. Students will fill in a sleep \& light exposure diary daily.
Study NCT04116151 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Cosmetic cream (Alantel (R): aloe vera, chamomile and thime)
Description: Application on the affected skin of the cream to be tested
Study NCT04116151 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Usual treatment
Description: Application on the affected skin of the emollient and moisturizing substance
Study NCT06596499 — intervention group
Intervention type: DEVICE
Intervention: CH-VAD
Description: The CH-VAD pump is a fully magnetically levitated (maglev), centrifugal continuous-flow blood pump.
Study NCT06614751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DAT-2645 tablet
Description: The patient will be randomized into 2 groups and take DAT-2645 tablet daily. dosage is optimal dose-1 or optimal dose-2, 21day/ Cycle. The subject of this part is to optimize dosage and definite RP2D.
Study NCT06614751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DAT-2645 tablet
Description: The study set 6 dose level cohorts in dose escalation part.On C0D1, patient take DAT-2645 one time (Single use), The dosage is same as his enrolled cohort dose level. if no DLT, 7 days later(C1D1), patients will continue taking DAT-2645 tablet daily, dasage is same as before, 21days/cycle.
Study NCT06616961 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide Pen
Description: In this study, the intervention involves administering semaglutide (Fitaro) to participants for weight management. The treatment protocol includes the following steps:~Initial Dose: Participants will start with a subcutaneous injection of semaglutide at a dose of 0.25 mg once weekly for the first four weeks to allow for tolerance and adjustment.~Dose Escalation: After the initial period, the dose will be increased at four-week intervals as follows:~Week 5: Increase to 0.5 mg Week 9: Increase to 1 mg Week 13: Increase to 1.7 mg Week 17: Increase to a maximum dose of 2.4 mg, if necessary, based on individual weight loss response and tolerability.
Study NCT06616493 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesio taping
Description: measure the subjects' lower extremity biomechanical characteristics with 3 different conditions respectively (kinesio taping, placebo kinesio taping, no taping)
Study NCT06616493 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: kinesio taping
Description: measure the subjects' lower extremity biomechanical characteristics with 3 different conditions respectively (kinesio taping, placebo kinesio taping, no taping)
Study NCT06617676 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous tibial nerve stimulation
Description: Two electrodes will be place over the tibial nerve over the medial ankle. The electrical stimulation will be turned up to patient tolerance at a sensory level only.
Study NCT06615830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard chemotherapy
Description: Each patient will receive the standard first-line chemotherapy (chosen among Gemcitabine-Abraxane, or Abraxane-Gemcitabine-FOLFOX or FOLFIRINOX, based on the clinical judgement of the treating oncologist) until disease progression.
Study NCT06615830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Organoid-guided treatment
Description: Upon disease progression confirmed radiologically, the patients will receive second-line chemotherapy. Second-line chemotherapy will be selected among the most promising effective drug (or drug regimens) as predicted in vitro by their benchmarking on patient-derived organoids.
Study NCT06617624 — intervention group
Intervention type: OTHER
Intervention: MRI
Description: Healthy volunteer will have a non-injected cardiovascular MRI
Study NCT06617624 — intervention group
Intervention type: OTHER
Intervention: MRI Contrast
Description: Patients will have the gadolinium injected cardiovascular MRI
Study NCT06676293 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Anti-PD1
Description: Pembrolizumab 100mg in normal saline 100ml infusion over 30 minutes for every two month
Study NCT06676293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD1
Description: Pembrolizumab 100mg in normal saline 100ml infusion over 30 minutes for every two month
Study NCT06676293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: asparaginase
Description: The patients will receive asparaginase 10000IU/vail IM QD for three or five days.
Study NCT06615934 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic and resistance exercise
Description: From the first day of transplantation in the ICU until 10 days after transfer to the ward or discharge from the hospital, if needed, the patients of the group will undergo respiratory physiotherapy once a day. The process of this program includes patient assessment, clinical decision-making, and implementation of therapeutic interventions.~The interventions of the therapeutic exercise group are divided into three phases:~1. From the time the patient enters the ICU until the time of extubation;~2. From the time of extubation to the time of transfer to the ward;~3. Duration of the patient's stay in the ward.
Study NCT06615934 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic and resistance exercise
Description: From the first day of transplantation in the ICU until 10 days after transfer to the ward or discharge from the hospital, if needed, the patients of the group will undergo respiratory physiotherapy once a day. The process of this program includes patient assessment, clinical decision-making, and implementation of therapeutic interventions.~The interventions of the therapeutic exercise group are divided into three phases:~1. From the time the patient enters the ICU until the time of extubation;~2. From the time of extubation to the time of transfer to the ward;~3. Duration of the patient's stay in the ward.
Study NCT06615934 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Respiratory physiotherapy
Description: The participants of this group will receive respiratory physiotherapy daily after transplant until discharge.
Study NCT06617637 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic Based Virtual Reality Exercise Training
Description: With Aerobic Based Virtual Reality Exercise Training, participants will perform aerobic exercise training with the Xbox Kinect 360 game Your Shape Fitness Evolved 2012. Your Shape Fitness Evolved 2012 is a game that requires basic coordination and is designed to improve the fitness levels of individuals. The game is used as an entertaining aerobic training tool that includes many aerobic activities such as boxing, yoga, dancing, etc. with adjustable difficulty levels.
Study NCT06617637 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Aerobic Exercise Training
Description: Using a treadmill, participants will be put through an exercise training consisting of a 10-minute warm-up at 0 degree incline, a 20-30-minute (by increasing the walking time by 5 minutes at the end of the first four weeks and the beginning of the last four weeks) walking at 40-80% of the heart rate reserve (moderate-vigorous intensity) and a 10-minute cool-down period. Treadmill walking levels will be changed if necessary to ensure the targeted exercise intensity.
Study NCT06461377 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucagon-like peptide-1 receptor agonist：Semaglutide
Description: The GLP-1RA intervention group was given subcutaneous injection of GLP-1RA for 3 months, while the control group was not given GLP-1RA intervention
Study NCT05571033 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Spinal reflex conditioning
Description: Each participant will serve as their own control. The intervention is 30 sessions. The first 6 sessions are baseline measures of reflexes. The remaining sessions will engage participants in learning how to decrease their reflex activity in their calf muscle on the more-affected leg. Each intervention visit will involve 20 trials in which participants do not get visual feedback about their performance, then 225 trials with visual feedback.
Study NCT05768932 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin is an Antineoplastic agent
Study NCT05768932 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a natural product with antitumor activity
Study NCT04758897 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell))
Description: Intratumoral injection only. The dosing date can be the Day 1 only or Days 1 through 5.
Study NCT06182319 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gastrografin
Description: Administration of WSC (Gastrografin) 2 hours after placement of NGT.
Study NCT06182319 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Administration of Saline 2 hours after placement of NGT.
Study NCT06182319 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SBO Treatment Without NG Tubes
Description: Patients who decline to have NG tubes placed will be enrolled and followed with the same outcomes protocol as the other patients in the trial
Study NCT05060562 — intervention group
Intervention type: OTHER
Intervention: COVID 19 positive
Description: Diagnosed as COVID 19 patient using Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab with suggestive symptoms.
Study NCT05060562 — intervention group
Intervention type: OTHER
Intervention: COVID 19 negative
Description: Suspected COVID 19 patients who were tested negative using either Real-Time Polymerase Chain Reaction (RT-PCR) with the nasopharyngeal swab, or Rapid Antigen test of nasopharyngeal swab.
Study NCT06424639 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Luspatercept
Description: Luspatercept (dose of 1.0 mg/kg, subcutaneous injection every 3 weeks) Cyclosporine (3-5mg/kg/day)
Study NCT06424639 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclosporine
Description: Cyclosporine (3-5mg/kg/day)
Study NCT05708066 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavender Aromatherapy
Description: Participants will have the Bioesse lavender patch placed on the chest, according to manufacturer recommendations.~After the lavender patch has been in place for 5 minutes, the same VAS anxiety questionnaire will be provided
Study NCT05708066 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Non-scented Tab
Description: A non-scented tab will be placed on the participant's chest, according to manufacturer recommendations. Participants in this group will only receive the initial VAS anxiety questionnaire.
Study NCT05851768 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Bupivacaine 0.25%
Study NCT05851768 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine + Magnesium
Description: Bupivacaine 0.25% + Magnesium
Study NCT05851768 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine + Dexmedetomidine
Description: Bupivacaine 0.25% + Dexmedetomidine
Study NCT03598972 — intervention group
Intervention type: OTHER
Intervention: intervention
Description: elementary analysis
Study NCT04004845 — intervention group
Intervention type: DRUG
Intervention: Cytotec
Description: Misoprostol 25mcg vaginal
Study NCT04004845 — intervention group
Intervention type: DRUG
Intervention: oxytocin
Description: Oxytocin 10 IU/ml Solution for infusion
Study NCT04004845 — intervention group
Intervention type: DEVICE
Intervention: Cervical Foley Balloon
Description: Cervical Foley will be inflated to 80cc
Study NCT05126329 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: amcenestrant
Description: tablet for oral use
Study NCT05012644 — intervention group
Intervention type: DRUG
Intervention: Palbociclib + aromatase inhibitor
Description: Palbociclib + aromatase inhibitor
Study NCT05012644 — intervention group
Intervention type: DRUG
Intervention: Aromatase inhibitor
Description: Aromatase inhibitor
Study NCT06214221 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Signos System
Description: The intervention involves the use of the Signos System, a combination of a proprietary software application with a continuous glucose monitor (CGM), to manage weight in overweight and obese adults.
Study NCT06214221 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Lifestyle Education
Description: In the Standard Lifestyle Education arm, participants receive conventional advice on diet and exercise, focusing on general healthy lifestyle habits to manage weight.
Study NCT05605444 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single bout of exercise
Description: isometric wall squat at a knee joint angle of 100 degrees. Instruct participant to place their back against the wall with feet positioned parallel and spaced shoulder-width apart. Lower themselves down until they reached a knee joint angle of 100 degrees. Measure knee joint angle by placing a goniometer on the lateral epicondyle of the knee, in line with the femur whilst the anchor arm was in line with the lateral malleolus.
Study NCT06629064 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Working Memory Training
Description: Computer-administered working memory training program. WMT is a modified working memory capacity task designed to train working memory functioning. WMT is designed to contain high interference across trials and is adaptive to performance. As participants improve working memory, the task becomes more difficult.
Study NCT06629064 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Training
Description: The Sham condition requires participants to complete a similar computer task for the same length of time. The Sham Training is a modified working memory capacity task designed to place less demands on working memory.
Study NCT06711315 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Oral Mucosit Care Protocol
Description: The children in the intervention group were subjected to a four-stage intervention carried out by the nurse researcher. The practices in each stage were as follows.~Stage 1: Oral care protocol training to prevent oral mucositis Stage 2: Introduction and application of training material (brochure) Stage 3: Introduction and implementation of oral care calendar Stage 4: Implementation of oral care protocol
Study NCT05266352 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised exercise program
Description: A structured program consisting of range of motion, postural control, scapulothoracic strengthening, glenohumeral strengthening and dynamic stabilization exercises used in conservative treatment of rotator cuff tears will be performed for 8 weeks.~Patients will do the exercises under control of the physiotherapist in the clinic.
Study NCT05266352 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Home exercise program
Description: A structured program consisting of range of motion, postural control, scapulothoracic strengthening, glenohumeral strengthening and dynamic stabilization exercises used in conservative treatment of rotator cuff tears will be performed for 8 weeks.~Patients will do the exercises at home. Patients will visit the clinic every 2 weeks and progression of exercise program will be made.
Study NCT05502211 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: induction of anaesthesia using fentanyl
Study NCT04836351 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Concentrated rehabilitation for patients with persistent symptoms post COVID-19
Description: 3+ 1-2 days concentrated rehabilitation for patients with persistent symptoms post COVID-19 with a mobile application follow-up and physical consultations at 3 months post intervention.
Study NCT05502211 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine IV
Description: induction of anesthesia using lidocaine
Study NCT06629727 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: VR Group
Description: the experimental group was shown a video through VRG during the lithotripsy procedure.
Study NCT06629727 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: Patients received standard care during the procedure
Study NCT06629662 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve gastrectomy
Description: Sleeve gastrectomy with laparoscopic or robotic approach
Study NCT05206890 — intervention group
Intervention type: DRUG
Intervention: fluzoparib monotherapy or combination therapy
Description: patients with epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer who underwent fluzoparib monotherapy or combination therapy
Study NCT05380583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CRAFT-EP
Description: CRAFT-EP is a behavioral intervention delivered via telehealth with the option for one in-person session (when local guidelines allow in-person care without masks). The coaching session topics include self-care, communication, functional analysis, positive reinforcement, treatment engagement, natural consequences, problem solving, and planning next steps. The intervention is designed for families of individuals experiencing psychosis and substance use who are enrolled or seeking enrollment in early psychosis outpatient services. Participants will be asked to complete assessments at pre-, mid- (approximately week 4), post-intervention, and a follow-up assessment approximately 12 weeks post-intervention.
Study NCT05380583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TAU
Description: Participants may continue to receive their ongoing treatment, if any, which may include psychosocial and/or pharmacological interventions.
Study NCT05380583 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: TAU
Description: Participants may continue to receive their ongoing treatment, if any, which may include psychosocial and/or pharmacological interventions.
Study NCT04699604 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Levocetirizine Dihydrochloride
Description: At the end of the HILD assessment participants will be randomized to Levocetirizine Dihydrochloride or placebo. Children will be randomized by an investigational pharmacist to add-on either Levocetirizine dihydrochloride/ Xyzal® (UCB, Inc.) immediate release oral solution 2.5mg/5ml (2.5mg in children 6-11 years of age; 5mg in children >11 years per recommended doses) or placebo to their current asthma regimen.
Study NCT04699604 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06101394 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab-IRDye800
Description: Infusion of the study drug will be performed 2-5 days before the surgery: the patients will receive 100 mg of cetuximab intravenously over 30 minutes and a dose 50 mg of cetuximab-IRDye800 over 30 minutes to 1 hour.