AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04962672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol group
Description: 20 patients scheduled for the elective craniotomy for suspected high-grade gliomas resection will be enrolled and further randomized to receive total intravenous anesthesia (propofol group). Standard fasting and monitoring guidelines will be instituted. All patients will be induced and intubated after administration of intravenous boluses of fentanyl, propofol and rocuronium. For the maintenance phase of anesthesia, patients in the propofol group will receive continuous infusions of propofol and remifentanil. No patients will receive nitrous oxide. Anesthesia will be titrated to keep depth of anesthesia between 35- 55. All patients will be maintained on oxygen in air mixture (40%) and titrate the End Tidal Carbon Dioxide (ETCO2) concentration between 25-30 mm Hg.
Study NCT04962672 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane group
Description: 20 patients scheduled for the elective craniotomy for suspected high-grade gliomas resection will be enrolled and further randomized to receive Volatile (sevoflurane group) agent for the maintenance phase of anesthesia. Standard fasting and monitoring guidelines will be instituted. All patients will be induced and intubated after administration of intravenous boluses of fentanyl, propofol and rocuronium. For the maintenance phase of anesthesia, patients in the volatile inhalational anesthesia group received a volatile inhalational agent (sevoflurane) and remifentanil infusion. No patients will receive nitrous oxide. Anesthesia will be titrated to keep depth of anesthesia between 35- 55. All patients will be maintained on oxygen in air mixture (40%) and titrate the End Tidal Carbon Dioxide (ETCO2) concentration between 25-30 mm Hg.
Study NCT04831567 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MIBG-I131
Description: Radiopharmaceutical
Study NCT04745130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab，regofinib，cetuximab
Description: KRAS BRAF wild type Sintilimab 200mg d1q3w+ regofinib 80mg d1-21 q4w with cetuximab 500mg/m2 q2w
Study NCT04745130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KRAS BRAF mutant Sintilimab + regafinil
Description: KRAS BRAF mutant Sintilimab 200mg D1 Q3W + regafinil 80mg D1-21 Q4W
Study NCT04950998 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Moving Up - A
Description: Moving Up - A is a physical activity smartphone app for persons with mild cognitive impairment or mild forms of dementia. The app includes a personally tailored set of messages, tips, strategies, and tasks designed to increase physical activity levels and disrupt extended periods of sedentary time. Users also have the ability to track their steps and and sedentary behavior time as well as their progress towards activity goals.
Study NCT05091047 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Erchonia EVRL
Description: 42 procedure administrations with the Erchonia® EVRL™ administered by the subject at home: Twice daily procedure administrations for 3 weeks.
Study NCT05248048 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-T infusion
Description: NKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer
Study NCT06290479 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Air Up® Peach Pod
Description: Participants in this arm will use the air up® drinking system with a peach-flavored pod.
Study NCT06290479 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Air Up® Orangeade Pod
Description: Participants in this arm will use the air up® drinking system with an orangeade-flavored pod.
Study NCT04883931 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: 0.5 ml 0.9% normal saline will drop on both eyes twice in a day.
Study NCT04883931 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Breast milk
Description: 0.5 ml breast milk from all infant's own mother will drop both eyes twice in a day
Study NCT04313088 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Eluxadoline 100 mg
Description: Eluxadoline 100mg by mouth twice daily with food
Study NCT06388239 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban 5MG
Description: Apixaban 5 mg Film-coated tablets
Study NCT06388239 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Apixaban 5MG
Description: Apixaban 5 mg Film-coated tablets
Study NCT05246878 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EDP-235
Description: Oral administration
Study NCT05246878 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match EDP-235, oral administration
Study NCT04089852 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrous oxide gas for inhalation
Description: All inhaled gases will be administered via nasal mask using a portable nitrous oxide/oxygen (N2O/O2) machine. Environmental safety will be maintained with an N2O scavenger system and Porter Miniature Vacuum System. The treatment group will receive inhaled N2O/O2. The N2O will be gradually up-titrated to a goal ratio of 70/30 N2O/O2 and will be administered as outlined in the treatment arm description.
Study NCT04089852 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxygen Gas for Inhalation
Description: All inhaled gases will be administered via nasal mask using a portable nitrous oxide/oxygen (N2O/O2) machine. The control group will receive inhaled O2 alone. Control group participants will receive 100% O2 for two minutes prior to speculum placement. Inhaled oxygen will be administered continuously throughout the procedure as outlined in the control arm description.
Study NCT05848076 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TNE
Description: McGill exercise focuses on the ability of the spine to stabilize in different positions 3 sets of 3 repletion with of each of muscle and briefly explains the patient about their pain
Study NCT05848076 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: core stability
Description: McGill exercises for the low back.
Study NCT05848076 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: core stability
Description: McGill exercises for the low back.
Study NCT04227626 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GlucoSTAT
Description: Closed-loop blood glucose control using intravenous insulin and dextrose
Study NCT05841719 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Screening test
Description: Capillary blood sampling by finger-prick devices and second confirmatory venous sampling when needed.
Study NCT05533944 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Simulation training in Boškoski-Costamagna ERCP Trainer
Description: Coached simulation training in Boškoski-Costamagna ERCP Trainer, by participating in three intensive courses during the first three months of training, with a monthly basis
Study NCT06365658 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Psychological assessment
Description: Psychological assessment of memory, learning and language
Study NCT04884880 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Luo-Fu-Shan Plaster
Description: Luo-Fu-Shan Plaster 10g，once daily，4 weeks
Study NCT04884880 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: The placebo 10g
Description: Placebo 10g，once daily，4 weeks
Study NCT05010070 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: diet and lifestyle program
Description: See description of main arm.
Study NCT05745103 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy with AI
Description: Cognitive behavioral therapy is a psycho-social intervention that aims to reduce symptoms of various mental health conditions, primarily depression and anxiety disorders. The Eleos Health platform provides real-time data that optimizes this therapy and helps the provider tailor the intervention to the specific client.
Study NCT05745103 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioral therapy
Description: Cognitive behavioral therapy is a psycho-social intervention that aims to reduce symptoms of various mental health conditions, primarily depression and anxiety disorders.
Study NCT04819529 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early and Intensive Occupational Therapy
Description: Occupational therapists will implement the following activities:~* Polysensory stimulation: external stimulation for increasing the level of alertness. It will be implemented with SAS 1 one session each 48 h and SAS 2 one session each 24 h.~* Cognitive stimulation: bundle of exercises for activating mental functions, i.e: alertness, visual perception, memory, calculus, problem solving, praxis, language. Patients with SAS 3, 4 and 5. In SAS \<2, 6> environmental orientation will be considered~* Basic activities of daily living (BADLs): promotion of independence that initially practice hygiene, personal grooming. Patients with SAS 3, 4 and 5~* Motor function Stimulation: exercises to keep the patient's upper extremities active and functional. Patients with SAS with 3,4 and 5. Patients with SAS 1 and 2 will use adaptations to prevent edema and bedsores on vulnerable body areas~* Education: daily visits by trained family members and health staff about the intervention process
Study NCT06043180 — intervention group
Intervention type: PROCEDURE
Intervention: Transcatheter aortic valve implantation
Description: Intervention on aortic valve for severe aortic stenosis
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C1K
Description: Subcutaneously administrate C1K 150mg at 0 Day 1, Day 8, Day 15
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C1K
Description: Subcutaneously administrate C1K 300mg at 0 Day 1, Day 8, Day 15
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneously administrate placebo at 0 Day 1, Day 8, Day 15
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C1K
Description: Subcutaneously administrate C1K 600mg at 0 Day 1, Day 8, Day 15
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C1K
Description: Subcutaneously administrate C1K 900mg at 0 Day 1, Day 8, Day 15
Study NCT05980065 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C1K
Description: Subcutaneously administrate C1K 1200mg at 0 Day 1, Day 8, Day 15
Study NCT06547762 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hybrid approach (in-person and remote) to pediatric rehabilitation: A look beyond the COVID-19 crisis
Description: Hybrid rehabilitation. Out patients will receive one day a week of remote therapy and the remaining (1-4 days) in person at rehabilitation hospital
Study NCT04858607 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample
Description: Serology, immune status, T cell immunity, and T cell aging.
Study NCT04858607 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Saliva sample
Description: Antibody tests
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Nutritional Risk Screening-2002
Description: Nutritional Risk Screening-2002
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Nutritional Risk Index
Description: Nutritional Risk Index
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Mini Nutritional Assessment
Description: Mini Nutritional Assessment
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Glasgow Prognostic Score
Description: Glasgow Prognostic Score
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Prognostic Nutritional Index
Description: Prognostic Nutritional Index
Study NCT05830968 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Morpheus8 Applicator Radiofrequency device
Description: Eligible subjects will receive 2 treatments with the Morpheus8 according to the study protocol. All participants will return for 2 follow up visits: 4 weeks (1M FU) and 12 weeks (3M FU) after the 2nd treatment. Total expected study duration is \~6 months, depending on subject recruitment rate.
Study NCT05722782 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Piroxicam
Description: Patients allocated to this arm received , as a second line treatment of renal colics , a five days treatment with 20 mg piroxicam per day and were contacted at the seventh day by telephone call to investigate the efficacy and the side effects of the treatment
Study NCT05722782 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen
Description: Patients allocated to this arm received , as a second line treatment of renal colics , a five days treatment with 1000 mg Acetaminophen per day and were contacted at the seventh day by telephone call to investigate the efficacy and the side effects of the treatment
Study NCT05722782 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients allocated to this arm received , as a second line treatment of renal colics , a five days treatment with placebo per day and were contacted at the seventh day by telephone call to investigate the efficacy and the side effects of the treatment
Study NCT06347783 — intervention group
Intervention type: DEVICE
Intervention: Insulin pump
Description: Continuous subcutaneous insulin therapy.
Study NCT05285267 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Parent Support
Description: Parent training on effective child management strategies
Study NCT05285267 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Shared Parent-Child Activities
Description: Structured parent-child activities
Study NCT05285267 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: COACHES
Description: This intervention involves practice of parenting strategies with facilitator monitoring and support.
Study NCT05417672 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Anthropometric measurements
Description: middle arm circumference
Study NCT05417672 — intervention group
Intervention type: DEVICE
Intervention: Handgrip strength test
Description: Handgrip strength test
Study NCT04230616 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: total knee arthroplasty
Description: total knee arthroplasty
Study NCT04230616 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: CT scan
Description: The first 52 participants will recieve a pre- and postoperative CT scan of the hip, knee and ankle.
Study NCT04690517 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: tracheal ultrasound
Description: When checking tracheal ultrasound, several signs are used in judgements. Direct signs include reverberation artifact and double ring sign. Indirect sign means checking the bilateral lung sliding.
Study NCT06449326 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Intermittent theta burst stimulation
Description: Intermittent theta burst stimulation (iTBS) is an efficient form of transcranial magnetic stimulation that allows up to 10x more pulses to be delivered in a given timeframe compared to conventional stimulation patterns.
Study NCT06449326 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Intermittent theta burst stimulation
Description: Intermittent theta burst stimulation (iTBS) is an efficient form of transcranial magnetic stimulation that allows up to 10x more pulses to be delivered in a given timeframe compared to conventional stimulation patterns.
Study NCT05941689 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AI-assisted colonoscopy
Description: AI can not only detect suspicious lesions timely, and label them in the field of view of the colonoscopy, but also monitor withdrawal speed and calculate the clean withdrawal time automatically.
Study NCT05581290 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AI-Flex
Description: A flexible multi-modal bio-sensing device with integrated AI capability used to measure ECG (heart's electrical activity), body temperature, and PPG (blood volume in tissue); primarly mounted on the wrist and chest.
Study NCT05498402 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: i-gel ® device
Description: Ventilations will be delivered through an i-gel ® device
Study NCT05498402 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: bag-valve-mask ventilation
Description: Ventilations will be delivered using a bag-valve-mask
Study NCT06473298 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual Light Tracking
Description: visual light tracking program consists of 10 tasks every task lasts for 6 minutes and may be repeated for the child especially in the first sessions to give him trials to him/her to understand the exercise.
Study NCT05322915 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: line dancing
Description: The intervention included 60-minute sessions, two days a week for four weeks for a total of eight sessions. All sessions were administered by the physiotherapist who has 26 years of experience in dance therapy. The dance was performed on a one to one basis with minimal support from the therapist. The line dancing sequence, which was specially created for this training program, was designed as a structured goal-oriented dance. Line dancing movements/steps are comprised of moving forward and backward, or sideways and turns and scuff. In addition, the fact that one foot is always in contact with the ground makes it ideal for patients with multiple sclerosis, who may have balance problems.
Study NCT04774380 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Participants will receive durvalumab via IV infusion on Day 1 of each cycle.
Study NCT04774380 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Participants will receive cisplatin via IV administration on Day 1 of each cycle.
Study NCT04774380 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Participants will receive carboplatin via IV administration Day 1 of each cycle.
Study NCT04774380 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Participants will receive etoposide via IV administration on days 1 to 3 of each cycle.
Study NCT04821934 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TR
Description: TR is a specific remote tele rehabilitation program on exercise activity managed by the physiotherapist (PT) at home, this is the experimental group. PT will explain the rehabilitation program at hospital discharge by the use of a brochure and videos. TR will include an early exercise re-conditioning program \[aerobic exercise at the free body (with or without tools), cyclette and walking with a pedometer\] comprising 20 sessions of 60 minutes/day, 6 out of 7 days to be performed at home, for one month after discharge. The sessions will be self-managed by the patients 4 times a week and an expert PT will remotely supervise 2 times a week through a dedicated platform. The program will be progressively incremental and divided into 4 different levels of intensity (0- 3).~In addition to this specific rehabilitation program, the patients will be followed by a nurse tutor once a day for two weeks and once a week for a further two weeks in a program of Telesurveillance.
Study NCT04821934 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TSu
Description: The patients of this group will perform a usual Telesurveillance and will be considered as control group.~All patients, at discharge from the hospital, will be provided with a finger pulse oximeter and a dedicated application (app) on their personal smartphone and will be advised on free physical activity to be performed at home. The nurse will check through scheduled calls (once a day for two weeks and once a week for a further two weeks) the patient's health condition, vital parameters and drugs administration. Patients will be able to contact the nurse at each time, in case of specific need, out of the scheduled call, 7/7 days.~A follow up by phone will be planned by nurse tutor at 2 months from the end of the study.
Study NCT05895097 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Left bundle branch pacemaker
Description: Left bundle branch pacing (LBBP) will be the pacing technique. In brief, after localizing the His bundle area the LBBP lead will be positioned approximately 1-1.5 cm distal to the His bundle position in the right ventricular septum. Before screwing the lead deep into the interventricular septum, the suitable position will be confirmed by fluoroscopic signs and adequate paced QSR morphology. Final lead position will be confirmed according to ECG parameters. Given that the pacing parameters with LBBP are typically low and stable, backup RV lead will not be mandatory.
Study NCT05895097 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional pacing
Description: Right ventricular pacing in patients with LVEF ≥ 40% and cardiac resynchronization therapy in patients with LVEF \< 40 %
Study NCT05183074 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MR-linac
Description: 1.5-Tesla MR-linac based SBRT
Study NCT05982912 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: breath sampling
Description: We collect a breath sample of exhaled air and analyse the VOC profile in this sample
Study NCT06285552 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Positive parenting PAIF program
Description: Psychoeducational intervention in a group format driven by a practitioner with 6 to 12 sessions where caregivers learn parenting competences