AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05082974 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OC-01 (varenicline 0.6mg/ml) nasal spray
Description: OC-01 (varenicline 0.6mg/ml) nasal spray which contains varenicline is being developed by Oyster Point Pharma for the treatment of signs and symptoms of Drye Eye Disease. OC-01 (varenicline) nasal spray activates the trigeminal parasympathetic pathway and stimulates natural tear production to bathe the corneal nerve endings in a protective layer of tear film. In addition, OC-01 (varenicline) acts as a cholinergic agonist and may provide analgesia by activating the trigeminal parasympathetic pathway.
Study NCT05082974 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (vehicle) nasal spray
Description: Placebo (vehicle) nasal spray \[control\]
Study NCT05282563 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: double and a half layered esophagojejunal anastomosis
Description: After the end of esophagojejunostomy, 3/0 barbed suture or absorbable suture was used. First, the anastomotic site was sutured continuously for one circle, with the suture spacing of 3-4 mm and the width of 4-5 mm. Then, the continuous horizontal mattress type seromuscular layer varus suture was used to embed the anastomotic stoma for one circle, and the suture width was 5\~8 mm above and below the anastomotic stoma. After the completion of esophagojejunostomy, the full-thickness reinforcement of the anastomosis and the embedding of the seromuscular layer can ensure the complete anastomosis of the mucosal layer of the anastomosis. The embedding of the seromuscular layer can also improve the anti-pressure and anti-tension of the anastomosis, and provide a guarantee for the primary healing of the anastomosis.
Study NCT05379842 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education on a healthy lifestyle and health literacy
Description: Traditional motivational face-to-face workshops with lifestyle (nutritional, physical activity, sleep) advice every 3 months
Study NCT05379842 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education on a healthy lifestyle and health literacy
Description: E-learning and digital (with videos -YouTube channel or WhatsApp/text message) educational workshops with lifestyle (nutritional, physical activity, sleep) advice every 15 days
Study NCT05327504 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Written Exposure Therapy
Description: Written Exposure Therapy is a 5 session treatment in which individuals write about their trauma event in a specified manner.
Study NCT05327504 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Neutral Topic Writing
Description: Treatment as Usual augmented by 5 sessions of Neutral Topic Writing which involves writing about specific objects (e.g., what they have eaten over the past week) or events (e.g., what they did since yesterday) in detail without discussing thoughts or feelings.
Study NCT05523375 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive Lifestyle Intervention
Description: Trained health coaches deliver the active intervention - a comprehensive, high-intensity program, as recommended first-line therapy by the 2013 American Heart Association/American College of Cardiology/The Obesity Society Guidelines.
Study NCT04921332 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bright Light Therapy (BLT) Lamp
Description: With its built in automatic timer shut-off function, the bedside registered nurse (RN) would not need to return to the room to turn off this lamp after 30 minutes because the lamp will automatically shut off on its own.
Study NCT05614921 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ultrasound guided external oblique intercostal plane block
Description: ultrasound guided external oblique intercostal plane block 30 ml local anesthetic each side
Study NCT05614921 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Wound infiltration
Description: 5 ml local anesthetic for each trocar side
Study NCT05730972 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical acupoint stimulation
Description: The patients are taken in the recumbent or sitting position, and the local skin at the acupoints is routinely disinfected. A pair of conductive gel patch, connecting to the Huatuo SDZ-ⅡB portable electronic needle therapy instrument, are respectively affixed to the ipsilateral acupoint group, so as contralateral side.
Study NCT05730972 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcutaneous electrical acupoint stimulation
Description: The electroacupuncture instrument has a normal screen display as the Huatuo SDZ-ⅡB portable electronic needle therapy instrument, but could not output current normally.
Study NCT05730972 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Routine palliative treatment
Description: The patients in both groups received routine palliative treatment of tumors, such as chemotherapy, immunotherapy, targeted therapy, drug analgesic therapy, nutrition support, and so on.
Study NCT05730972 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Routine palliative treatment
Description: The patients in both groups received routine palliative treatment of tumors, such as chemotherapy, immunotherapy, targeted therapy, drug analgesic therapy, nutrition support, and so on.
Study NCT05540782 — intervention group
Intervention type: BEHAVIORAL
Intervention: PROMIS-SF v2.0 -Cognitive Function 8a
Description: Patient-Reported Outcomes (PROs)
Study NCT05808517 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi
Description: Tai Chi (TC) is a traditional Chinese exercise, also known as a mind-body exercise. It is suitable as an alternative or supplementary form of routine physical exercise for older adults. TC focuses on gentle and rhythmical movements while maintaining a meditative state. Low to moderate activities have benefits to improve sleep disturbances in older adults. In addition, growing evidence widely supports meditation as a potential intervention to improve sleep disturbances through reducing repetitive negative thoughts such as worry and rumination.
Study NCT05808517 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tai Chi
Description: Tai Chi (TC) is a traditional Chinese exercise, also known as a mind-body exercise. It is suitable as an alternative or supplementary form of routine physical exercise for older adults. TC focuses on gentle and rhythmical movements while maintaining a meditative state. Low to moderate activities have benefits to improve sleep disturbances in older adults. In addition, growing evidence widely supports meditation as a potential intervention to improve sleep disturbances through reducing repetitive negative thoughts such as worry and rumination.
Study NCT05808517 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: repetitive transcranial magnetic stimulation
Description: The brain stimulation technique repetitive transcranial magnetic stimulation (rTMS) provides the opportunity to non-invasively modulate cortical excitability. In general, low-frequency rTMS (≤ 1 Hz) is thought to inhibit cortical excitability.
Study NCT05629507 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: The Virtual Reality intervention will administer through the use of a Virtual Reality headset. The multimedia contents in VR, will have a video quality from 4K to 8K, 360 degrees, and HD audio stereo.~The scenarios are classified into 12 categories: 1) Artistic cities (60 scenarios); 2) Africa (17 scenarios); 3) Hills (26 scenarios); 4) Rivers, lakes and waterfalls (43 scenarios); 5) Sardinia (13 scenarios); 6) Deserts (21 scenarios); 7) Beaches (20 scenarios); 8) Animals (20 scenarios); 9) Mountains (25 scenarios); 10) Concerts (21 scenarios); 11) Sea (24 scenarios); 12) submarine (20 scenarios).
Study NCT05349383 — intervention group
Intervention type: DRUG
Intervention: Antibody-Drug Conjugate
Description: Compared the case reporting of sepsis-related toxicities among ADC and other common cancer drug therapies.~ADC:including Gemtuzumab Ozogamicin, Trastuzumab Emtansine, Inotuzumab Ozogamicin, Enfortumab vedotin, Trastuzumab deruxtecan, Sacituzumab govitecan, Brentuximab Vedotin, Moxetumomab pasudotox, Polatuzumab Vedotin, Belantamab Mafodotin, loncastuximab tesirine and Tisotumab vedotin.
Study NCT05349383 — intervention group
Intervention type: DRUG
Intervention: Antineoplastic and immunomodulating agents other than Antibody-Drug Conjugate
Description: We would like to include other common cancer drug therapies such as chemotherapy, targeted therapy, immunotherapy and so on as a comparator group.
Study NCT05852821 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 5STS remote assessment via videoconference
Description: Patients will be asked to perform several times the 5STS test, from their home through videoconference, on 3 occasions (day 1, 24h later and 1month later).
Study NCT02001584 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baclofen
Study NCT02001584 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Memantine
Study NCT02001584 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Study NCT05077007 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous nephrolithotomy
Description: Endoscopic stone Extraction from the kidney by making a puncture and dilate a tract direct into the kidney through muscle wall and renal parenchyma
Study NCT05077007 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporeal Shock Wave Lithotripsy
Description: Using Shock waves from outside the body targeted at a kidney stone causing the stone to fragment. The stones are broken into tiny pieces.
Study NCT06097546 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: laboratory test (RAI14 and MACC-1 )
Description: Measurement of serum RAI14 and serum MACC-1 levels by immunochemical assays
Study NCT04948840 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood sampling
Description: Blood sample of 7 mL whole venous blood in an EDTA citrate tube (4.5 mL) and a PAXgene Blood RNA tube (2.5 mL).
Study NCT05778253 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: WES and ctDNA detection
Description: WES and ctDNA detection
Study NCT06153706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Subgingival application of L-PRF loaded with metronidazole
Description: After phase I therapy, L-PRF loaded medical grade metronidazole was applied sub gingivally into the pockets using blunt gauge needle and Perio-pack was placed (two applications with one week apart were applied subgingivally.
Study NCT06153706 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Subgingival application of L-PRF
Description: The L-PRF alone was applied subgingivally into the pockets and Perio-pack was placed (two applications with one week apart.
Study NCT05431322 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Initially give loading dose with 0.5 mcg/kg for 10 min and then keep maintenance dose with 0.5 mcg/kg/h until two-lung ventilation.
Study NCT05371899 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Chiauranib
Description: Take Chiauranib 50mg orally once daily
Study NCT05507736 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: 13 Indwelling, sterile and disposable needles (SEIRIN NEW PYONEX® from 0.9 mm in length and 0.22 mm in diameter) on day 1 and 5 of the second cycle of irinotecan leaving them inserted for 4 days.
Study NCT05167097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ASSIST-linked Brief Intervention
Description: WHO's ASSIST-linked Brief Intervention (with and without Steps 6-9, the decisional balance element)
Study NCT05167097 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Mindset Intervention
Description: Standard mindset manipulation as used in research by Peter M. Gollwitzer and colleagues
Study NCT05167097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindset Intervention
Description: Standard mindset manipulation as used in research by Peter M. Gollwitzer and colleagues
Study NCT06171074 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CM310
Description: CM310 injection
Study NCT05323370 — intervention group
Intervention type: OTHER
Intervention: 24h urine
Description: Urine samples will be collected at home over 24 hours
Study NCT05323370 — intervention group
Intervention type: OTHER
Intervention: urine sample
Description: A urine sample of 20cc will be collected
Study NCT05088135 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bilateral Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM.
Description: It will be divided three groups as bilateral Auricular Vagus Nerve Stimulation (VSS). Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM. Auricular Vagus Nerve Stimulation will be performed for 20 minutes with a frequency of 10 Hz and a pulse width of 300 µs.
Study NCT05088135 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Unilateral-Right Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM.
Description: It will be divided three groups as unilateral-right Auricular Vagus Nerve Stimulation (VSS). Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM. Auricular Vagus Nerve Stimulation will be performed for 20 minutes with a frequency of 10 Hz and a pulse width of 300 µs.
Study NCT05088135 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Unilateral-Left Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM.
Description: It will be divided three groups as unilateral-left Auricular Vagus Nerve Stimulation (VSS). Auricular Vagus Nerve Stimulation will be performed with a device called VAGUSTIM. Auricular Vagus Nerve Stimulation will be performed for 20 minutes with a frequency of 10 Hz and a pulse width of 300 µs.
Study NCT05617417 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Local applied injectable platelet-rich fibrin in women with stress urinary incontinence
Description: Injectable platelet-rich fibrin was prepared by centrifuging venous blood taken from women with stress urinary incontinence and applied locally to the anterior vaginal wall of the patients.
Study NCT04469504 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prehabilitation program
Description: 4-week trimodal prehabilitation program: Exercise, nutritional supplementation, and psychological support
Study NCT04469504 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Oral Impact
Description: perioperative immunonutrition by ORAL IMPACT
Study NCT04518306 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telmisartan 10 mg/amlodipine 1.25 mg/indapamide 0.625 mg
Description: Oral tablets
Study NCT06262009 — intervention group
Intervention type: OTHER
Intervention: human faecal collection
Description: collecting stools 6 times over a 90 days period and complete a questionnaire at the same times: D1, D7, D15, D30, D60 and D90
Study NCT06262009 — intervention group
Intervention type: OTHER
Intervention: ancillary study
Description: interviews and/or ethnographic observations for 50 volunteers
Study NCT05672225 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine 0.2mcg/kg/hr (2ml/hr) administration via continuous channel in the experimental group
Study NCT04518306 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Telmisartan 20 mg/amlodipine 2.5 mg/indapamide 1.25 mg
Description: Oral tablets
Study NCT05672225 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Normal saline 2ml/hr administration via continuous channel in the experimental group
Study NCT06188299 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Restricted Fluid Administration
Description: Restrictive fluid administration generally consists of partial or no replacement for the intravascular expansion from anesthesia, in which case vasopressors are usually administered, no replacement for the third space loss, and only partial replacement for deficits from preoperative fasting.
Study NCT05423912 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Couple in Control (CiC) Program
Description: MCI dyads engaging in the pilot testing aim of the CiC Program meet in virtual intervention group meetings lasting 90 to 120 minutes over the course of 8-9 consecutive weeks. Participants are asked to take part in structured quantitative interviews at baseline and 4 and 8 weeks post-intervention. A subsample of participants will be interviewed virtually via videoconference for a 30 to 60 minute discussion on their experiences in and perceptions of the intervention.
Study NCT04518306 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT04768660 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: gum
Description: Other: Chewing gum ChiczaTM organic chewing gum 6 pieces a day Other: Glucose 12ml glucose solution (13,6g) per day
Study NCT04639011 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Duloxetine
Description: Three doses of 60 mg of oral duloxetine will be given to participants (right before operation, postop day 1, postop day 2)
Study NCT04639011 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Three doses of placebo will be given to participants (right before operation, postop day 1, postop day 2).
Study NCT04639011 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care (SOC) for tibial plateau surgery
Description: Postoperative IV administration of opioids via a patient controlled analgesia (PCA) system which utilizes a hydromorphone pump.
Study NCT04639011 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of care (SOC) for tibial plateau surgery
Description: Postoperative IV administration of opioids via a patient controlled analgesia (PCA) system which utilizes a hydromorphone pump.
Study NCT05720468 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Combined endurance and resistance exercise training
Study NCT04709328 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SCTA01
Description: Diluted by 0.9% normal saline，IV
Study NCT05720468 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: No Exercise
Description: Continue usual level of physical activity; option to participate in exercise training program after 26-week intervention period
Study NCT06233149 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esomeprazole magnesium dihydrate-Test product
Description: Esomeprazole magnesium dihydrate 40 mg tablets Manufactured by: Cipla Limited, India
Study NCT05015686 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd
Description: live varicella-zoster virus in 0·5 mL of sucrose, sodium glutamate,sodium chloride,potassium chloride,sodium dihydrogen phosphate, potassium dihydrogen phosphate and injection water per injection
Study NCT06233149 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esomeprazole magnesium dihydrate-Reference product
Description: Esomeprazole magnesium dihydrate 40 mg tablets Manufactured by: AstraZeneca AB, Kingdom of Sweden
Study NCT06221748 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab Vedotin Injection
Description: Phase II and III study ：2.5mg/kg, intravenous infusion，D1, every 2 weeks
Study NCT06221748 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab Injection
Description: Phase II and III study ：6.0mg/kg, intravenous infusion，D1, every 2 weeks.
Study NCT06221748 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel Injection
Description: Phase II and III study ：Calculate dosage based on body surface are,160mg/m2,intravenous infusion，D1,D8 every 3 weeks
Study NCT06175169 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Information of Appendix (IA) model
Description: Deep learning model
Study NCT05173961 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-Based Intervention
Description: Use oncpatient mobile application
Study NCT05173961 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Complete survey
Study NCT05756569 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood
Study NCT05756569 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study NCT05756569 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enfortumab Vedotin
Description: Given IV
Study NCT05756569 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05756569 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Given IV
Study NCT05512013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibuprofen 800 mg
Description: Ibuprofen taken orally 2 hours prior to exercise
Study NCT05512013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Celecoxib 200mg
Description: Celebrex taken orally 2 hours prior to exercise
Study NCT05512013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flurbiprofen 100 mg
Description: Flurbiprofen taken orally 2 hours prior to exercise
Study NCT04709328 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: IV
Study NCT05512013 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inert placebo taken orally 2 hours prior to exercise
Study NCT05756569 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies