AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06393855 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: single-step Trans-PRK
Description: Both eyes were treated consecutively in each patient by single-step Trans-PRK performed by SCHWIND Amaris 500 S excimer laser platform (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany). Topical Proparacaine Hydrochloride Eye Drops 0.5% (Alcaine, Alcon, Fort Worth, TX, USA) were used to anesthetize the eyes, and use povidone-iodine to disinfect the eyelid skin. After a lid speculum had been inserted, and the other eye was blocked. Epithelial and stromal ablations were performed using a single continuous laser shooting session on an excimer laser platform. After the appeals step, Mitomycin C 0.02 % was applied to the stromal surface for 20 s, then rinse with cold salt water.
Study NCT06393855 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Placing a bandage contact lens on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye.
Description: After surgery. A contact lens placed on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye.
Study NCT06393855 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Placing a bandage contact lens on the cornea,A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
Description: After surgery. A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
Study NCT04636515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: F520
Description: 200mg，Q3W
Study NCT06244394 — intervention group
Intervention type: RADIATION
Intervention: intensity-modulated radiotherapy
Description: All patients were staged according to the 8th edition of the TNM classification by the American Joint Committee on Cancer/Union for International Cancer Control and received a standardized treatment regimen including IMRT and concurrent or adjuvant chemotherapy. Inverse IMRT treatment planning was performed on a Varian Inspiration Platform (version 10.0), using the simultaneous integrated boost technique. The prescribed doses were 68-75 Gy to the PTV of the GTVnx in 32-34 fractions; 64-75 Gy to the PTV of the GTVnd in 32-34 fractions; 60 Gy to the PTV of CTV1 in 32 fractions; and 50 Gy to the PTV of CTV2 in 28 fractions. All patients were given one fraction daily 5 days a week. The dose-volume-histograms (DVHs) of the organs at risk were evaluated as described in the radiation therapy oncology group (RTOG) 0225 protocol to prevent violation of the tolerance limits.
Study NCT06367244 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transplant Wellness Program - Kidney and Liver
Description: The exercise prescription for the intervention will be multimodal, , will follow current chronic disease exercise guidelines, and will be tailored to meet the unique needs of each participant. . All participants will receive two 30-45-minute individual session with a CEP during their first week and two additional sessions during the second week if needed. The individual sessions will be followed by group sessions. Each participant will get a total of 24 individual and group sessions combined. These sessions can be conducted either in-person or online, based on participant preference and TWP logistics. For aerobic-based activities, a moderate rate of perceived exertion of 4-6 on a scale of 0-10 will be used. Resistance exercise will begin with functional movements and bodyweight exercises targeting major muscle groups with modifications for beginners and exercise progressions when deemed. Balance and flexibility training activities will also be included.
Study NCT05651815 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Graphene spectrum light wave therapy room
Description: Undergo 30-min of graphene adjuvant therapy every day for 7 d.
Study NCT06491784 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Therapy
Description: 12 week personalised exercise, nutrition and wellbeing programme
Study NCT06455865 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TPACK-Based Blended Learning Instruction
Description: The control group employed traditional in-person teaching methods, including face-to-face classroom instruction, reading from printed textbooks, and completing homework assignments. The curriculum covered the fundamental theories and skills related to information resource retrieval and usage but did not specifically utilize the TPACK framework. Students primarily received lectures and guidance from the instructor during class and completed assignments and learning tasks independently after class.
Study NCT04924270 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Faecal microbiota transplantation
Description: The capsule FMT transplant consists of faeces obtained from a thoroughly screened, unpaid, anonymous stool donor. Each FMT product is made from 50g faeces diluted in sterile saline (0.9% NaCl) and glycerol, blended, centrifuged and filtered to remove particulate material before transfer to double-layered capsules. The FMT capsules will be stored at - 80 ⁰C until use. On the day of the FMT, the FMT capsules will be thawed to room temperature before treatment.
Study NCT04924270 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules consist of NaCl (0.9%) and glycerol added brown food colouring.
Study NCT06185075 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implant crown delivery
Description: Dental implant crown will be designed, fabricated by a dental lab, and delivered.
Study NCT06244264 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autoblood transfusion
Description: Through a negative pressure suction device, the patient's blood that flows out during surgery is collected into a blood storage filter. During the suction process, it is mixed with an appropriate anticoagulant and passed through multiple layers of filters. When the volume of recovered blood reaches a certain level, it is continuously (or intermittently) centrifuged. Using a high-speed centrifugal blood recovery tank, the red blood cells are separated, and the plasma, waste, cell fragments, anticoagulants, and harmful components are diverted into a waste bag. A large amount of saline is used to repeatedly wash, purify, and concentrate the red blood cells. Finally, the concentrated red blood cells are prepared into a 70% red blood cell suspension with saline and stored in a collection bag for transfusion back to the patients. Open surgery is considered as the standard procedure for metastatic spinal cord compression
Study NCT06215963 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App for Independence-O (A4i-O)
Description: A4i-O is a digital health platform designed to support individuals with opioid use disorders. A4i-O will focus on providing education on treatment options, recovery navigation, social activation and connections to a range of resources. It aims to assist with fostering self-management and recovery through identifying risks for relapse, navigating urges/cravings, coping with shame/guilt, avoiding relapse, moving forward after relapse, and lived experiences. Daily wellness and goal attainment check-ins to highlight mental health trajectories will be prompted. With appropriate consent from both the client and provider, a provider dashboard is accessible to the client's provider prior to their appointment, generating a summary of day-to-day wellness ratings, responses to reminders, goal progressions, and other self-reported measures from the platform.
Study NCT06327399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine infusion
Description: patients will receive Dexmedetomidine infusion dose of 1 mcg/kg over 10 min before induction.
Study NCT06327399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine bolus
Description: patients will receive Dexmedetomidine bolus dose of 0.3 mcg/kg over 60 seconds.
Study NCT06327399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atropine Sulfate
Description: If heart rate falls below 45 bpm, rescue dose (500 mcg) of atropine will be given.
Study NCT06327399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ephedrine
Description: If mean blood pressure decreases below 50 mmHg, boluses of 10 mg ephedrine will be given
Study NCT05814965 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endodontic treatment in the form of root canal treatment
Description: Patients will receive endodontic treatment, and inflammatory markers will be assessed
Study NCT05814965 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endodontic treatment
Description: Patients will receive endodontic treatment in the form of root canal treatment, and inflammatory markers will be assessed along with metabolic markers assessment
Study NCT05814965 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: assessment of inflammatory marker
Description: assessment of inflammatory markers
Study NCT05814965 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: inflammatory markers will be assessed along with metabolic markers assessment
Description: inflammatory markers will be assessed along with metabolic markers assessment
Study NCT04794530 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: cocoa flavanols
Description: The cocoa flavanols intervention is manufactured by Mars Inc. Participants randomized to cocoa flavanols will take two capsules daily of cocoa flavanols. The two capsules of cocoa flavanols will contain approximately 500 mg of cocoa flavanols and appoximately 80 mg of (-)-epicatechin.
Study NCT04794530 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: The placebo intervention will be manufactured by Mars Inc. and will appear identical to the cocoa flavanols intervention. Participants will take two capsules daily of placebo. The placebo will be a cellulose based capsule and will not contain cocoa flavanols or (-)-epicatechin.
Study NCT06489236 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vaccine Confidence: Skills to Promote Vaccination in the Pediatric Consultations
Description: Intervention mapping principles guided a multidisciplinary team through the development of the intervention. The intervention is a 12-hour training program focused on improving vaccination promotion and vaccine hesitancy management during pediatric consultations. The program comprises 10 hours of online education and 2 hours of in-person activities. Online training materials (short video lectures, video case studies, and readings) were structured in three learning modules covering vaccine and vaccine hesitancy technical information, vaccination promotion communication strategies, and practice organizational resources. In-person activities involved role-playings and group discussions. Intervention content is evidence-based. As a participation incentive, pediatric nurses and pediatricians who complete all program activities, including a multiple-choice final test, will receive 2,5 accredited continuing medical education credits.
Study NCT06372210 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo IEM tablet
Description: Oral placebo-embedded IEM tablet.
Study NCT06372210 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abilify MyCite®
Description: Oral aripiprazole-embedded IEM tablet.
Study NCT06372210 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: D-Tect Patch
Description: The D-Tect patch is a wearable sensor (WS) capable of detecting the ingestion of the IEM and measuring physiologic parameters. The WS automatically logs and stores the time when the IEM reaches the stomach and transmits the data to a smartphone.
Study NCT04905628 — intervention group
Intervention type: DEVICE
Intervention: Dexcom CGM System
Description: Dexcom CGM System
Study NCT05146830 — intervention group
Intervention type: OTHER
Intervention: Safety and Efficacy Assessments
Description: Safety evaluations, disease-specific assessments, and other assessments to monitor for long-term complications of gene therapy intervention.
Study NCT06581029 — intervention group
Intervention type: OTHER
Intervention: The multidimensional peer victimization scale (PVS)
Description: The multidimensional peer victimization scale (PVS), a self-report scale for children and adolescents, was used to assess the victimization
Study NCT05084924 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Cross-frequency transcranial alternating current stimulation via the NeuroConn Direct Current Stimulator Plus
Description: Stimulation will be delivered via the NeuroConn Direct Current Stimulator Plus, an investigational electrical non-invasive brain stimulation device that is being used for foundational neuroscience and translational research.
Study NCT05084924 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cross-frequency transcranial alternating current stimulation via the NeuroConn Direct Current Stimulator Plus
Description: Stimulation will be delivered via the NeuroConn Direct Current Stimulator Plus, an investigational electrical non-invasive brain stimulation device that is being used for foundational neuroscience and translational research.
Study NCT05084924 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cross-frequency transcranial alternating current stimulation via the NeuroConn Direct Current Stimulator Plus
Description: Stimulation will be delivered via the NeuroConn Direct Current Stimulator Plus, an investigational electrical non-invasive brain stimulation device that is being used for foundational neuroscience and translational research.
Study NCT05491486 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Group Therapy
Description: see above
Study NCT05291338 — intervention group
Intervention type: DRUG
Intervention: Doxorubicin
Description: no optimal dosage of doxorubicin in TACE procedures (ranging from 30 to 75 mg/m2 up to a maximum of 150 mg/m2 ) according to tumor size
Study NCT06436703 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Influenza ModRNA Vaccine
Description: Intramuscular injection
Study NCT06436703 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza Vaccine (QIV)
Description: Intramuscular injection
Study NCT06327399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Propofol 20 mg boluses till loss of contact
Study NCT04043468 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audit and feedback
Description: Audit and feedback (A\&F) is an intervention that aims to improve professionals practices by providing professionals with a summary of their performance over a period of time.
Study NCT04043468 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Audit and feedback
Description: Audit and feedback (A\&F) is an intervention that aims to improve professionals practices by providing professionals with a summary of their performance over a period of time.
Study NCT05291338 — intervention group
Intervention type: DRUG
Intervention: Lipiodol
Description: Lipiodol dose should be over 5 ml if tumor diameter is less than 5 cm, and the maximum dose will be 10 ml when the tumor develops to more than 5 cm in diameter.
Study NCT06582823 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health belief model-based community educational program
Description: The 5-week intervention includes two weekly 60-minute face-to-face sessions for 8-10 participants, two weekly telephone follow-ups, and a booster session.~Week 1: Focuses on increasing knowledge about atrial fibrillation (AF), its risks, complications, and treatment benefits. The principal investigator (PI) provides education using interactive methods and colored visuals.~Week 2: Emphasizes skill building for pulse palpation to detect irregular pulses. Participants learn through demonstrations and practice using a simulated arm.~Weeks 3-4:Telephone follow-ups monitor adherence to pulse checking and address barriers. Support and advice are provided by the PI.~Week 5: A booster session reinforces knowledge and skills with scenario-based practice and use of a simulated arm.
Study NCT06582823 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control group will receive an information leaflet presenting information about AF, health risks and complications associated with AF, common methods to screen for AF, and follow-up actions if positive screening results are suspected.
Study NCT06582472 — intervention group
Intervention type: PROCEDURE
Intervention: Ophthalmological examination including imaging assessments
Description: Ophthalmological examination including imaging assessments (SD-OCT, Spectral Domain Optical Coherence Tomography, a procedure to study and quantify possible retinal neurodegeneration and OCT-A, Optical coherence tomography angiography, a procedure to study and quantify possible retinal vascular abnormalities)
Study NCT06582472 — intervention group
Intervention type: PROCEDURE
Intervention: confocal analysis of cornea
Description: Confocal analysis of cornea: a procedure to study and quantify possible corneal nerve degeneration as a marker of involvement of diabetic neuropathy
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AT247
Description: Ultra rapid acting prandial insulin aspart
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: AT247
Description: Ultra rapid acting prandial insulin aspart
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NovoLog
Description: Rapid acting prandial insulin aspart
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NovoLog
Description: Rapid acting prandial insulin aspart
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fiasp
Description: Fast acting prandial insulin aspart
Study NCT05184868 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fiasp
Description: Fast acting prandial insulin aspart
Study NCT05430724 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Controlled hypotention
Description: The procedure to be applied to the cases to be included in the study:~Patients randomized by the sealed envelope method will be divided into 2 groups (40 patients in each group).~The sealed envelopes that determine which group the patient will belong to will be randomly selected by the patient.~Standard general anesthesia will be applied to all patients. Before starting the surgical procedure; Group N (Nicardipine infusion) will be administered at a dose of 5-15mg/h, and Group E (Esmolol infusion) at a dose of 50-300mcg/kg/min.~2) General anesthesia will be applied to all groups. Patients will be administered controlled hypotension (mean arterial pressure 50-60 mmHg).
Study NCT06582472 — intervention group
Intervention type: PROCEDURE
Intervention: Dynamic Vessel Analyzer (DVA)
Description: Dynamic Vessel Analyzer (DVA), a device that measures the response of retinal arteries and veins to a standardized stimulus (flickering light) allowing direct quantification of the inflammatory status of the retinal vasculature
Study NCT06582472 — intervention group
Intervention type: PROCEDURE
Intervention: tear sampling collection
Description: Collect and analyze tear samples to identify biomarkers in tears and at the endothelium of the ocular surface through impression conjunctival cytology and the quantitative/qualitative analysis of pro-inflammatory cytokines
Study NCT06582472 — intervention group
Intervention type: PROCEDURE
Intervention: blood sampling collection
Description: collection and analysis of blood samples to identify diabetic retinopathy biomarkers and early abnormalities of the vascular retinal system.
Study NCT05984485 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: neoadjuvant chemotherapy plus total mesorectal excision
Description: Neoadjuvant chemotherapy regimen recommended FOLFOX6, XELON, FOLFOX, mFOLFOX for 4-6 courses, and TME surgical treatment after preoperative tumor restaging 1-2 weeks after neoadjuvant chemotherapy.
Study NCT05984485 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: total mesorectal excision
Description: Standard total mesorectal excision
Study NCT06583356 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational interviewing
Description: Participants will receive motivational interviewing intervention previously, delivered face-to-face at participants' home, 1 session, followed by 2 brief follow-up sessions. Each session is expected to last approximately 30 to 45 minutes.
Study NCT06582459 — intervention group
Intervention type: DEVICE
Intervention: HFNC treatment
Description: HFNC treatment HFNC therapy. The initial flow rate of 50-60 L/min was subsequently adjusted to maintain an oxygen saturation (SpO2) ≥92%. The FiO2 was titrated to maintain the PaO2 between 60 and 80 mmHg.
Study NCT06582459 — intervention group
Intervention type: DEVICE
Intervention: NIV treatment
Description: NIV treatment A Mindray SV300 ventilator (Mindray Medical International Limited, Shenzhen, China) was used to deliver NIV via an oronasal mask. The initial inspiratory positive airway pressure (IPAP) was 12-15 cmH2O and adjusted later to achieve a tidal volume of 6-8 mL/kg of predicted body weight and a respiratory rate of \&amp;lt;30 breaths/min. The expiratory positive airway pressure (EPAP) was established at 5-8 cmH2O. Additional-ly, FiO2 was titrated to maintain a PaO2 between 60 and 80 mmHg.
Study NCT06581276 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Acceptance and Commitment Therapy (ACT)
Description: Acceptance and Commitment Therapy (ACT) is an evidence-based behavioral pain treatment intervention for Chronic Pain, anxiety and depression, and substance use disorders, being studied as a group-based therapy delivered by substance use counselors in an opioid treatment program.