AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05487378 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: PKU GOLIKE
Description: AA protein Substitute for the dietary management of PKU, PKU GOLIKE is a food for special medicinal purposes (FSMP) for the dietary management of PKU.
Study NCT05249127 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 64Cu-SAR-bisPSMA
Description: 64Cu-SAR-bisPSMA
Study NCT06622213 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mucoadhesive film with Acmella oleracea extract
Description: Apply 1 patch on ulcer 3 times per day (after meals)
Study NCT06622213 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triamcinolone Acetonide 0.1% Oromucosal Paste
Description: Apply ¼ inch on ulcer 3 times per day (after meals)
Study NCT06622213 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: mucoadhesive film without Acmella oleracea extract
Description: Apply 1 patch on ulcer 3 times per day (after meals)
Study NCT04980651 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Remote ischemic conditioning
Description: Remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 200 mm Hg.
Study NCT04980651 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham remote ischemic conditioning
Description: Sham remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 60 mm Hg.
Study NCT05818358 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: black beans
Description: ¾ cup of cooked black beans
Study NCT05818358 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: wheat berries
Description: ¾ cup of cooked whole wheat grain
Study NCT05818358 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: white rice
Description: ¾ cup of cooked white rice
Study NCT06025253 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Negative Pressure Wound Therapy
Description: Application of negative-pressure wound therapy (NPWT) post major lower extremity amputation
Study NCT06025253 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Wound Dressing
Description: Application of standard wound dressing post major lower extremity amputation
Study NCT05570851 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Cessation Text Messages
Description: Intervention condition will consist of a text message program designed to promote alcohol cessation tailored to HNC patients and targeted to VA or Civilian populations in addition to usual-care-advice.
Study NCT05570851 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Control condition will consist of a provider-delivered alcohol cessation intervention with usual-care-advice.
Study NCT06643767 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bexa and focus ultrasound
Description: The Bexa exam uses pressure elastography to produce a map of the breast tissue's elasticity to identify any masses. Focused ultrasound is then used to further classify the mass into a BIRADS category.
Study NCT06497764 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vibrational Anesthesia (VA) Device
Description: The half of the patient's scalp randomized to receive VA during PRP treatment will receive VA via the Buzzy bee-striped personal. The device is powered by two AAA batteries and is indicated for use for pain reduction. It uses the Melzack and Wall's Gait Control theory, which states that activation of non-nociceptive fibers can interfere with signals from pain fibers to inhibit overall sensation of pain.
Study NCT06497764 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PRP Treatment
Description: PRP (a needle-related procedure) will be delivered per routine standard of care.
Study NCT05750732 — intervention group
Intervention type: BEHAVIORAL
Intervention: Weight loss diet
Description: Participants in the study group will be given training on the weight loss diet, which is a routine part of their treatment.
Study NCT06295991 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Lycra garment
Description: Investigation of the effect on balance and respiratory functions by using specially produced lycra garments for 6 hours a day for 16 weeks
Study NCT06295991 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lycra garment
Description: Investigation of the effect on balance and respiratory functions by using specially produced lycra garments for 6 hours a day for 16 weeks
Study NCT06166043 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NURSE FOLLOW-UP PROGRAM SUPPORTED WITH WEB-BASED EDUCATION
Description: An online training consisting of 10 sessions in total for 5 weeks will be given to the patients in order to improve their fatigue management skills. In addition to this training, they will receive a nurse support program.
Study NCT05069311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Multimodal analgesia
Description: Multimodal analgesia includes the combination of:~1. morphine given by PCA (patient-controlled analgesia) at 1 mg/dose~2. bupivacaine 0.25% and dexmedetomidine 0.5 mcg/mL (total volume of 10 mL) by epidural-catheter bolus given preoperatively~3. bupicavaine 0.125% and dexmedetomidine 0.5 mcg/mL at a 5 mL/hour rate per epidural-catheter given intraoperatively~4. bupivacaine 0.1% and dexmedetomidine 0.5 mcg/mL given by programmed intermittent epidural bolus (PIEB), set to be delivered every one-hour~5. etericoxib 90 mg per oral give two-hours before surgery and then continued until three days post-surgery~6. paracetamol 1 g (intravenously) given on the day of the surgery, continued at 10 mg/kg dose every 8 hours until three days post-surgery
Study NCT05069311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Conventional intravenous analgesia
Description: Standard analgesia includes fentanyl 2 mcg/kg (bolus) and morphine given by PCA (patient-controlled analgesia) at 1 mg/dose
Study NCT05463237 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: oral glucose tolerance test
Description: oral glucose tolerance test (OGTT) used for the diagnosis of gestational diabetes mellitus between 24-28 weeks of gestation
Study NCT05463237 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sample
Description: Measurement of blood Visfatin, Vaspin and Omentin levels in pregnant women with diabetes
Study NCT05062330 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reproxalap Ophthalmic Solution (0.25%)
Description: Reproxalap Ophthalmic Solution (0.25%) administered 7 times over two consecutive days
Study NCT05062330 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Ophthalmic Solution
Description: Vehicle Ophthalmic Solution administered 7 times over two consecutive days
Study NCT05275751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TRPV1-inhibitor
Description: Pharmacological inhibition of TRPV1 during intradermal injection of hot synthetic interstitial fluid
Study NCT05275751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TRPM3-inhibitor
Description: Pharmacological inhibition of TRPM3 during intradermal injection of hot synthetic interstitial fluid
Study NCT06462612 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lumateperone
Description: Lumateperone 42 mg capsules administered orally, once daily
Study NCT06462612 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching capsules administered orally, once daily
Study NCT06447298 — intervention group
Intervention type: OTHER
Intervention: Satisfaction questionnaires
Description: Use of a post-laparoscopy satisfaction questionnaire designed to be adapted to the context of laparoscopic surgery. This post-laparoscopy questionnaire was inspired by the PedsQL generic care satisfaction questionnaire, a standardised and validated questionnaire.
Study NCT06570434 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: budoprutug
Description: monoclonal antibody
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asynchronous content only
Description: Receives asynchronous exercise content and no live training
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asynchronous content and health coaching and no live training
Description: Receives asynchronous content, health coaching and no live training.
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asynchronous content only and 1 on 1 live training
Description: receives asynchronous content and live 1 on 1 training
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asynchronous content and health coaching and 1 on 1 training
Description: receives asynchronous content, health coaching, and live training
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: asynchronous content and group training
Description: receives asynchronous content and live group training
Study NCT06207084 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asynchronous content and health coaching and group training
Description: receives asynchronous content, health coaching, and live group training
Study NCT06646601 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention of prevention
Description: A 6-month multidisciplinary preventive intervention for each patient: gardening, adapted physical activity, nutritional workshops.
Study NCT06647186 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non Incised Papillae Surgical Approach
Description: Ten patients were included in this group, phase I therapy (scaling, root planing and oral hygiene measures) was performed. A single horizontal or oblique incision was made in the mucosa located on the cortical bone tissue, apical to the intrabony defect. The mesiodistal extension of the incision was sufficient to allow access to the defect. Tissue coronal to the incision was raised to full thickness from the incision line to expose the bone peaks delimiting the intrabony defect. The granulation tissue was removed from the bone walls of the defect. Dental plaque and calculus deposits were removed from the root surface with ultrasonic scaler tips and micro-minicurettes. A solution of 24% Ethylenediaminetetraacetic acid (EDTA) was applied to the root surface for 2 min, irrigation with saline solution then allograft bone material was packed into the periodontal defect. The incision was sutured with horizontal internal mattress sutures then simple interrupted sutures.
Study NCT06647186 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional flap design
Description: Ten patients were included in this group, phase I therapy (scaling, root planing and oral hygiene measures) was performed. Intrasulcular incision was made splitting the buccal papilla from the palatal papilla. All defects were approached by elevating a flap only on the buccal side and leaving the oral portion of the interdental supracrestal soft tissues undetached. The full-thickness elevation of the marginal portion of the flap was performed with a microsurgical periosteal elevator.~After removal of granulation tissue from the bone walls of the defect, root and defect debridement was performed with manual and mechanical (ultrasonic) instruments with tips for subgingival instrumentation.~A solution of 24% Ethylenediaminetetraacetic acid (EDTA) was applied to the root surface for 2 min, irrigation with saline solution then allograft bone material was packed into the periodontal defect. The incision was sutured with simple interrupted sutures.
Study NCT06646744 — intervention group
Intervention type: BIOLOGICAL
Intervention: mRNA COVID-19 vaccine
Description: Children will be vaccinated according to standard local procedure
Study NCT05255276 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sitravatinib 50 mg
Description: 50 mg Sitravatinib on Day 1 (Group 1A)
Study NCT05255276 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sitravatinib 100 mg
Description: 100 mg Sitravatinib on Day 1 (Group 2A)
Study NCT05255276 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Itraconazole
Description: Itraconazole QD from Day 9 to Day 18, and Sitravatinib 50 mg at Day 12 (Group 1B)
Study NCT05255276 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rifampin
Description: Rifampin QD from Day 9 to Day 22, and Sitravatinib 100 mg at Day 16 (Group 2B)
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab deruxtecan
Description: trastuzumab deruxtecan 5.4 mg/kg IV on day 1
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: durvalumab 1500 mg IV on day 1
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Panitumumab
Description: panitumumab 6 mg/kg IV on days 1 and 15
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botensilimab
Description: botensilimab 1 mg/kg on day 1
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Balstilimab
Description: balstilimab 3 mg/Kg on days 1 and 15
Study NCT05845450 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: sotorasib 960 mg orally once daily from day 1 to 28
Study NCT05080283 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CP1110 Sound Processor System
Description: Sound Processor
Study NCT05080283 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nucleus 7 Sound Processor (model: CP1000) system
Description: Sound Processor
Study NCT05528913 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fasenra Prefilled Syringe
Description: Fasenra 60mg s.c. administration at weeks 0,4 and 8
Study NCT05528913 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo Solution
Description: Placebo s.c. administration at weeks 0,4 and 8
Study NCT04766255 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Soft Tissue graft augmentation
Description: Donor site:~SCTG group: The SCTG will be harvested in the palat,In order to extract the same thickness in each grafts a double-bladed knife (separated by 1,5mm) will be used. The donor area will be sutured.~Recipient site:~SCTG group: the connective tissue graft will be trimmed to the correct dimensions (10mm height, 12mm length and 1,5mm thick) and placed and secured at the recipient site with a resorbable 5-0 suture CM group: The CM graft (Geistlich Fibro-gide) will be trimmed to the indicated dimensions (10mm height, 12mm length) and placed and secured at the recipient site with resorbable 5-0 suture PADM Group: the ADM (NovoMatrix, Biohorizons, Birmingham AL) graft will be trimmed to the indicated dimensions (10mm height, 12mm length) and placed and secured at the recipient site with resorbable 5-0 suture
Study NCT04766255 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implant Placement
Description: A crestal incision will be made in the implant reception area, extending from the distal of the most mesial tooth to the mesial of the most distal tooth. A mucoperiosteal flap will be elevated in the most crestal part of the ridge. The receptor bed will be prepared following the established drilling protocol for the placement of a BioHorizons Tapered Pro Implant (Biohorizons, Birmingham AL). The diameter and length of the implant will be previously established during the implant study. Later a healing abutment will be placed.
Study NCT04766255 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implant Placement
Description: A crestal incision will be made in the implant reception area, extending from the distal of the most mesial tooth to the mesial of the most distal tooth. A mucoperiosteal flap will be elevated in the most crestal part of the ridge. The receptor bed will be prepared following the established drilling protocol for the placement of a BioHorizons Tapered Pro Implant (Biohorizons, Birmingham AL). The diameter and length of the implant will be previously established during the implant study. Later a healing abutment will be placed.
Study NCT04439019 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lifestyle and dietary modification program
Description: The OA Optimization Program is a lifestyle and dietary modification program. All Patients will be offered this optional program while they await orthopedic consultation. There is an initial group information session for participants followed by medical assessment which includes medical history and physical examination, a previous dietary history, a readiness for change assessment, and screening for contraindications to the program. The patients will then attend group counselling sessions every 3 months for 1 year, or until their surgical date.Patients are encouraged to attend sessions with a family member. Improvement in Quality of Life measures including pain and disability in patients with severe osteoarthritis, as well as improvements in markers of health such as BMI, waist circumference, blood pressure, medication use in diabetic and hypertensive patients, and markers such as serum lipids and markers of inflammation will be shown.
Study NCT05320107 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: 0.5mg/kg bodyweight (or 0.25mg/kg bodyweight) ketamine, will be determined in pilot study
Study NCT05320107 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% NaCl
Study NCT05275751 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: No pharmacological intervention
Study NCT05275751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chloride-channel inhibitor
Description: Pharmacological inhibition of a chloride channel during intradermal injection of hot synthetic interstitial fluid
Study NCT05689814 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Paraffin based Denture Fixative
Description: Denture fixative applied in strips to secure dentures in place
Study NCT05689814 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Paraffin based Denture Fixative
Description: Denture fixative applied in strips to secure dentures in place
Study NCT04924764 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy.
Description: Conventionally used intervention for subacute and chronic neck pain.
Study NCT05923593 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MAG oil oral nutritional supplement (ONS)
Description: The study product is suitable for use as an oral nutritional supplement (ONS).The study product contains MAG oil.
Study NCT05706181 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based leg heat therapy
Description: Participants will be required to perform 8 weeks of leg heat therapy using water-perfused pants 4 times per week, with each session lasting 60 min. Skin temperature will be heated to about 40 °C. The pants heating system (consisting of pants and a water circulator/heater) can finely and uniformly control these designated skin temperatures. Participants will be randomly assigned to a group and provided with the pant heating system as well as a log book in which they are required to track the dates of each session. Participants will also measure their blood pressure and heart rate prior to, during, and immediately after each heating session using a portable oscillometric device provided by our laboratory.
Study NCT05706181 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based sham therapy
Description: Participants will be required to perform 8 weeks of leg heat therapy using water-perfused pants 4 times per week, with each session lasting 60 min. Skin temperature will be heated to about 40 °C. The pants heating system (consisting of pants and a water circulator/heater) can finely and uniformly control these designated skin temperatures. Participants will be randomly assigned to a group and provided with the pant heating system as well as a log book in which they are required to track the dates of each session. Participants will also measure their blood pressure and heart rate prior to, during, and immediately after each heating session using a portable oscillometric device provided by our laboratory.
Study NCT03354520 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tailored Videos
Description: web-based OSA messages (videos featuring role models and coaching advice using motivational enhancement) addressing OSA barriers within a health literacy framework--to decrease cognitive load and render messages understandable and actionable. OSA messages were tailored based on focus group data in the previous study (group tailoring).
Study NCT03354520 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: OSA Treatment
Description: Web-based platform delivering messages promoting OSA self-efficacy. . All patients will view the introductory video, followed by the video cluster: Sleep, Health, and Well-Being; Sleep-Heart Health; Lifestyle Changes; and Sleep Hygiene.
Study NCT03354520 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Videos
Description: Patients in the control arm will also receive an iPad, providing access to standard online OSA health information (e.g., National Sleep Foundation) in an equivalent dose as in the intervention arm using pre-selected automatic alerts to access the website