AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06638619 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback Fixation Training
Description: This training type involves the use of microperimetry. Microperimetry is a visual field test that incorporates perimetry and retinal imaging and is a standard ophthalmic clinical technology. It allows for direct observation of the fundus, but uses an eye-tracking system to compensate for involuntary eye movements. A program designed to train patients to direct and hold their gaze at an eccentric location programmed by the controller will be used. When the participant directs their gaze towards the pre-programmed location, a sound of increasing frequency is emitted to let them know they are approaching the correct location. The sound stabilizes into a solid tone when the patient is gazing directly at the trained location (biofeedback) and they are asked to attempt to hold their gaze at this location for as long as possible.
Study NCT06638619 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Saccadic Reading Training
Description: Participants will be assigned to participate in an at-home reading program. The reading exercises consist of worksheets with letter and number combinations of increasing complexity and font sizes. They are intended to increase accuracy in identifying letters and numbers. Worksheets will initially be dispensed with larger font type and spacing and be graded at weekly intervals towards regular, newspaper-size print and spacing over the course of training.
Study NCT05664841 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: magic trick training
Description: A typical session will begin with the magician demonstrating a magic trick then revealing the secret move of the trick.The participants will learn and practice each trick. With assistance from the magician, participants will develop an oralstory presentation for the trick. After participants master one trick, the magician will demonstrate and teach the next.
Study NCT04853888 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: ATTACH™ Parenting Program
Description: ATTACH™ parenting program offers an innovative, novel approach to early intervention, focusing on improving parent-child relationship quality by targeting parents' underlying reflective function (RF)-the ability to better understand one's own and one's child's thoughts and feelings. RF is essential for high quality parent-child relationships and secure parent-child attachment, both tied to child development and health, especially cognition, communication and inflammation.~.
Study NCT06566183 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Guideline-directed medical therapy (GDMT)
Description: Participants receive guideline-directed medical therapy (GDMT).
Study NCT05560867 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: robot-assisted training
Description: These training platforms use gamified training tasks to improve motor control in the hemiparetic arm
Study NCT05572905 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Patients after overnight fast will cycle on ergo-meter for 60 minutes. No per-oral food intake will be allowed during the test. Level of the intensity of exercise will be determined as individual range of heart frequency (HF), oxygen consumption (VO2) and respiratory quotient (RQ) just bellow the aerobic threshold of the given participant (close to anticipated fatmax). These values will be obtained during maximal capacity stress test on cyclo-ergo-meter. This maximum stress test will be performed at least one week prior to the 60 minutes exercise to eliminate potential carry-over effect. Power output will be modulated during the 60 minutes of exercise to ensure keeping participants values of HF, RQ and VO2 in the given range. Blood will be sampled at 5 time points with interval of 30 minutes during the exercise (0, 30, 60, 90, 120) and 24 hours post-exercise.
Study NCT05572905 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting control
Description: The same participants will be monitored while resting for 120 minutes in calm environment. No peroral food intake will be allowed during the test. Fasting control will take place at least one week apart of the exercise. Blood will be sampled at 5 timepoints with interval of 30 minutes during the exercise (0, 30, 60, 90, 120) and 24 hours post-control.
Study NCT05548075 — intervention group
Intervention type: DRUG
Intervention: Psilocybin
Description: Up to 25mg of Psilocybin on 2 occasions.
Study NCT05548075 — intervention group
Intervention type: BEHAVIORAL
Intervention: Therapeutic support
Description: Psychological and physical therapeutic support
Study NCT06419127 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Timelapse incubation and PGT
Description: Patients will have their embryos cultured in a timelapse incubator and their PGT results will be compared to the data collected during timelapse incubation.
Study NCT06068816 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutrient-dense drink
Description: a nutrient-dense drink developed by FrieslandCampina in line with the European Society for Clinical Nutrition and Metabolism guidelines for the dietary management of older malnourished patients
Study NCT05487131 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: electrical stimulation
Description: different types of weak electrical stimulation will be used
Study NCT06574204 — intervention group
Intervention type: DRUG
Intervention: Erythromycin
Description: The researchers injected 30 units of erythromycin into the inner right wrist of the subjects, which is a liquid dosage form.
Study NCT06574204 — intervention group
Intervention type: DRUG
Intervention: Azithromycin
Description: The researchers injected 30 units of azithromycin into the inner right wrist of the subjects, which is a liquid dosage form.
Study NCT06574204 — intervention group
Intervention type: OTHER
Intervention: physiological saline
Description: The researchers injected 10-20 μl of physiological saline into the inner left wrist of the subjects, which is a liquid dosage form.
Study NCT06573827 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood and urine sample evaluation
Description: Blood and urine sample evaluation will be performed in healthy female volunteers.
Study NCT06573268 — intervention group
Intervention type: DEVICE
Intervention: robot surgery device
Description: SPRA used da-Vinci SP system (SPRA) BABA used da-Vinci Xi system (BABA)
Study NCT06573125 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MoodMover
Description: MoodMover is a 9-week app-based program aimed at increasing physical activity (PA) among individuals with depression, delivered via Pathverse. The current version of MoodMover includes one introductory module for baseline self-monitoring, eight primary modules, and eight optional supplementary modules. The program uses a variety of formats to deliver educational content, including videos, podcasts, and illustrated articles. In addition to its structured psychoeducational content, the app provides a range of behavioral features.
Study NCT06497517 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GSK5464714- Camlipixant
Description: GSK5464714- Camlipixant will be administered
Study NCT06561113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Caffeine intake
Description: One cup of Turkish coffee contains 60 mg/65 ml (1 Turkish coffee cup) of caffeine. Participants will be instructed to sit for 10 minutes before drinking coffee. To prepare the Turkish coffee, 5 g of ground dry coffee will be mixed in 100 mL of tap water and left to boil in a coffee machine. When the first boil starts, it will be removed from the machine and poured into the cup. Then, 65 ml of Turkish coffee will be given to the subjects to ensure oral caffeine intake.
Study NCT06573645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Patients will be randomized to receive either rituximab 500 mg/m2 or rituximab 375 mg/m2 for six cycles of R-CHOP (21 days per cycle), followed by two maintenance cycles of rituximab (21 days per cycle).
Study NCT06573645 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rituximab
Description: Patients will be randomized to receive either rituximab 500 mg/m2 or rituximab 375 mg/m2 for six cycles of R-CHOP (21 days per cycle), followed by two maintenance cycles of rituximab (21 days per cycle).
Study NCT06566183 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coronary artery bypass grafting (CABG)
Description: Participants receive coronary artery bypass grafting (CABG).
Study NCT06566183 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous coronary intervention (PCI).
Description: Participants receive percutaneous coronary intervention (PCI).
Study NCT05027945 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Allogeneic HSCT
Description: stem cell transplant on day 0
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Busulfan test dose
Description: 0.8 mg/kg IV over 2 hours. May be skipped if real-time PKs are done during conditioning.
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mycophenolate mofetil (MMF)
Description: Mycophenolate mofetil (MMF): 15 mg/kg IV over 2 hours BID starting on day +5 until approximately day +35 (+/-2 days)
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Starting on day +5, start at 0.02 mg/kg IV continuous infusion over 24 hours until day +180 and titrated to trough levels of 5-15 mg/ml.
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Busulfan
Description: AUC Targeted Dose based on busulfan test dose PKs, IV infusion over 3 hours once daily (3.2 mg/kg IV per day will be the default dose) per the below time frame: For 8/8 Matched Related or Unrelated Donor Busulfan dose will be on days -6, -5, and -4 For 7/8 Matched Related or Unrelated or Haploidentical Donor Busulfan dose will be on days -4 and -3
Study NCT05027945 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Total Body Irradiation (TBI)
Description: For 7/8 Matched Related or Unrelated or Haploidentical Donor, 200cGy on day -1
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: 40 mg/m2 IV over 30 mins daily For 8/8 Matched Related or Unrelated Donor Fludarabine dose will be on days -6, -5, -4, and -3 For 7/8 Matched Related or Unrelated or Haploidentical Donor Fludarabine dose will be on days -6, -5, -4, -3, and -2
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide (CY)
Description: For 7/8 Matched Related or Unrelated or Haploidentical Donor, prior to transplant 14.5 mg/kg IV daily on days -6 and -5
Study NCT05027945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Post-Transplant Cyclophosphamide (PTCY)
Description: Post-Transplant Cyclophosphamide: 50 mg/kg IV daily over 2 hours on days +3 and +4, dosed according to ideal body weight
Study NCT04998188 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Collagen
Description: Patients will be treated with a single injection of collagen (2 ml) in the knee joint affected by osteoarthritis
Study NCT04998188 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (saline solution)
Description: Patients will be treated with a single injections of saline solution (2 ml) in the knee joint affected by osteoarthritis
Study NCT06371079 — intervention group
Intervention type: DEVICE
Intervention: phakic intraocular lens implantation traditional
Description: patients with refractive errors undergo surgical implantation of a lens inside the eye (implantable collamer lens or ICL) to correct these refractive errors. The procedure is done with help of use of both cohesive and dispersive OVD
Study NCT06371079 — intervention group
Intervention type: DEVICE
Intervention: phakic intraocular lens implantation reduced OVD
Description: patients with refractive errors undergo surgical implantation of a lens inside the eye (implantable collamer lens or ICL) to correct these refractive errors. The procedure is done with help of use of only cohesive OVD without using dispersive OVD.
Study NCT05393765 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yönetebilirim
Description: Yönetebilirim is an interactive web-based program developed to improve the self-management skills of individuals with MS by supporting self-regulation under the leadership of nurses.
Study NCT06306573 — intervention group
Intervention type: DEVICE
Intervention: CardioMEMS HF System
Description: The CardioMEMS HF System provides pulmonary artery (PA) hemodynamic data to monitor and manage HF subjects. The CardioMEMS HF System measures PA pressure which clinicians use to initiate or modify HF treatment.
Study NCT05165173 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: NanoD4CKD
Description: Participants will receive a 7-day supply of the 4-ounce almond milk mixed with 4000 IUs of nanoparticles of D3 and instructed to consume it in the morning with a meal.
Study NCT05165173 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: MicroD4CKD
Description: Participants will receive a 7-day supply of the 4-ounce almond milk mixed with 4000 IUs of microparticles of D3 and instructed to consume it in the morning with a meal.
Study NCT05629117 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized Diabetes Text Messaging (DB-TEXT) combined with Peer Support Education
Description: Patients who are assigned to the DB-TEXT+PSE group will receive personalized short text message services twice weekly at approximately noon on Monday and Thursday for three months (12 weeks). Furthermore, they will receive the peer support education weekly from the peer supporter by telephone during three months
Study NCT05629117 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Personalized Diabetes Text Messaging (DB-TEXT)
Description: Personalized Diabetes Text Messaging (DB-TEXT)
Study NCT06496711 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cancer Patients; Institutions and their employees in the treatment and/or counseling of cancer patients
Description: The study population will be surveyed at 3 yearly measurement time points by means of questionnaires and interviews on attitudes, barrier and support factors for participation in exercise therapy.
Study NCT06563440 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Digital app and information system
Description: A custom digital app and information system that consists of four modules: (1) ID module - captures child's demographic and biometric data and builds a printable QR-code; (2) Assay module - captures point of care test image, interprets, and transmits results to the central ministry of health data center; (3) Education module - stores and plays back short educational videos for pre- and post-screening counseling; (4) SCD e-Passport module - entry and display of child's salient clinical information.
Study NCT06563440 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Digital app and information system
Description: A custom digital app and information system that consists of four modules: (1) ID module - captures child's demographic and biometric data and builds a printable QR-code; (2) Assay module - captures point of care test image, interprets, and transmits results to the central ministry of health data center; (3) Education module - stores and plays back short educational videos for pre- and post-screening counseling; (4) SCD e-Passport module - entry and display of child's salient clinical information.
Study NCT06564272 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KC1036
Description: For patients weighing between 30 kg and less than 50 kg, administer 40 mg QD of KC1036. For patients weighing between 50 kg and less than 70 kg, administer 50 mg QD of KC1036. For patients weighing 70 kg or more, administer 60 mg QD of KC1036. 4 weeks as a cycle.
Study NCT05517005 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hype Bites Supplement
Description: The ingredients of the vitamin supplement are:~Chocolate liquor Sugar Cocoa butter Vanilla extract Vitamin B12 (as methylcobalamin) Tapioca Gum arabic Coloring (radish, apple, black currant) Carnauba Wax
Study NCT04296071 — intervention group
Intervention type: OTHER
Intervention: Research study
Description: Blood and tracheal aspirates will be collected
Study NCT06381401 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine 0.25%
Description: superficial cervical plexus block using 10 ml of bupivacaine 0.25%
Study NCT06381401 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine 0.125%
Description: superficial cervical plexus block using 10 ml of bupivacaine 0.125%
Study NCT06248671 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin 40mg
Description: Each tablet will be taken once daily for 84 days.
Study NCT06248671 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Each tablet will be taken once daily for 84 days
Study NCT06248671 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin 20mg
Description: Each tablet will be taken once daily for 84 days.
Study NCT06547814 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard implementation webinar and online training
Description: The one-hour webinar (either live or pre-recorded) will include updated information about the COVID-19 virus, variant nomenclature, vaccine eligibility, mechanisms of action, and outcomes. The 30-minute online training addresses how to communicate about COVID-19 vaccinations, presents a 5-step process for initiating conversations, includes example verbiage about how to address specific concerns, and has example videos that show how to implement the 5-step process with vaccine hesitant patients.
Study NCT06547814 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual facilitation
Description: This intervention involves a 30-minute virtual facilitation site visit and at least 8, 30-minute virtual facilitator coaching sessions. The virtual site visit over Zoom will establish the personnel and workflows at each pharmacy and allow the facilitator to establish rapport. Weekly Zoom calls will allow the virtual facilitator to work with a participant to review overall implementation challenges associated with approaching patients, delivering the intervention, and documenting results. Lastly, either the facilitator or the participant can request and schedule a Zoom call to go over any pressing implementation issue in need of rapid attention (e.g., technical difficulties with the website).
Study NCT05388136 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional follow up schedule with imaging
Description: Frequent of follow up visit and imaging
Study NCT05388136 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Deintensified follow up schedule without imaging
Description: Less intense follow up visit without imaging
Study NCT04843332 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Health Worker Support
Description: For those in the experimental group, a community health worker will provide health education and support as described in the Community Health Worker Intervention arm.
Study NCT06414265 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter mitral valve replacement
Description: The SATURN TS TMVR System will be implanted through a transcatheter approach in patients with symptomatic mitral regurgitation.
Study NCT06156046 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: skin prick test
Description: Skin prick test for bee venom
Study NCT06156046 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: IgE/G and T cell tolerance studies
Study NCT06565689 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YK012
Description: YK012 is a bispecific antibody targeting CD19 on B cells and CD3 on T cells leading to T cell-mediated cytotoxicity of malignant B cells
Study NCT05302414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Board game-based learning
Description: The team of PGY doctors and nurses received 3 hours training intervention in resuscitation teamwork skills through a board game-based teaching approach.
Study NCT05302414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Simulation-based learning
Description: The team of PGY doctors and nurses received 3 hours training intervention in resuscitation teamwork skills through a simulation-based teaching approach.
Study NCT05302414 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lecture-based learning
Description: The team of PGY doctors and nurses received 3 hours training intervention in resuscitation teamwork skills through an interactive lecture-based approach.
Study NCT05264818 — intervention group
Intervention type: PROCEDURE
Intervention: Glycocheck
Description: Assessment of the sublingual microvascularization
Study NCT05264818 — intervention group
Intervention type: PROCEDURE
Intervention: Ophthalmological examinations
Description: Description :~Measurement of best corrected distance visual acuity with ETDRS (Early Treatment Diabetic Retinopathy Study) Measurement of intraocular pressure by aplanation and forced air tonometer Central corneal thickness measurement with OCT (Optical Coherence Tomography) Non-mydriatic retinophotography Humphrey 24-2 visual field OCT-RNFL (Optical Coherence Tomography - retinal nerve fiber layer)
Study NCT05726318 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Antibiotics
Description: Participants will be provided either nitrofurantoin 100 mg oral twice a day for 5 days, trimethoprim/sulfamethoaxole 875/125 oral twice a day for 3 days, fosfomycin 3g once oral, ciprofloxacin 250 mg oral twice a day for 5 days or cephalexin 500 mg oral twice a day for 5 days
Study NCT05726318 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotics
Description: Participants will be provided either nitrofurantoin 100 mg oral twice a day for 5 days, trimethoprim/sulfamethoaxole 875/125 oral twice a day for 3 days, fosfomycin 3g once oral, ciprofloxacin 250 mg oral twice a day for 5 days or cephalexin 500 mg oral twice a day for 5 days