AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04779372 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: smartphone-based dCBT-I from a Wechat applet
Description: Participants will receive 6-week smartphone-based dCBT-I from a Wechat applet.
Study NCT04779372 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: sleep education
Description: Participants will receive sleep education like the advices getting from common sleep clinic.
Study NCT05724823 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Physical Activity Seated Exercises (V-PASE)
Description: The seated exercise program includes a variety of upper and lower limb strengthening, core strengthening, agility (fast arm and leg movements), and flexibility exercises. Participants will be supervised during each session thru videoconferencing by a trained instructor.
Study NCT04743167 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgery
Description: Laparoscopic treatment of endometriotic lesions
Study NCT04743167 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: IVF
Description: Up to three completed cycles of IVF
Study NCT04594447 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Physica Kinematic Retaining knee replacement
Description: modular knee prosthesis with a Kinematic Retaining (KR) mechanism and posterior cruciate ligament (PCL) preservation
Study NCT04594447 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Physica Cruciate Retaining knee replacement
Description: modular knee prosthesis with posterior cruciate ligament (PCL) preservation
Study NCT06001086 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamb Vedotin ,pyrotinib
Description: Disitamb Vedotin combined with pyrotinib
Study NCT05393284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OPL-0401 Dose 1
Description: Pharmaceutical Form: Capsule; Route of Administration: Oral
Study NCT05393284 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical Form: Capsule; Route of Administration: Oral
Study NCT05438368 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: bi-4SCAR GD2/CD70 T cells
Description: Infusion of bi-4SCAR GD2/CD70 T cells at 10\^6 cells/kg body weight via IV
Study NCT05316701 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Orca-T
Description: an allogeneic stem cell and T-cell immunotherapy biologic
Study NCT05316701 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard-of-Care
Description: unmanipulated donor allograft
Study NCT05773989 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CYP2C19 genotype guided P2Y12 monotherapy
Description: Patients without a LOF-allel will receive clopidogrel monotherapy (tablet of 75mg once daily) for 6 months. Patients with a LOF-allel will receive ticagrelor (tablet of 90mg twice daily) or prasugrel (tablet of 10mg once daily) for 6 months.
Study NCT05773989 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel
Description: Standard DAPT according to current guidelines with clopidogrel (tablet of 75mg once daily) for 6 months and acetylsalicylic acid (tablet 80mg one daily) for 6 months.
Study NCT05880550 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ultrasound cavitation in addition to aerobic ex
Description: Ultrasonic cavitation was turned on, the program of cavitation 40 kHz was chosen, the time was adjusted at 30 minutes. The cavitational head was moved very slowly on each abdominal segment in a small circular movement for 5 minutes. After finishing the focused ultrasound of the 6 segments of the abdomen, the skin was cleaned with cotton.~in addition to that the patients will receive aerobic exercises for 40 minutes.
Study NCT05880550 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: aerobic exercises.
Description: the patients will do aerobic training for 40 minutes on a bicycle ergometer.
Study NCT04789278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Notification
Description: Notification of coronary calcium to the patient and their clinician
Study NCT06237985 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ProTaper Gold file system
Description: According to the manufacturers ' instructions, root canal treatments will be conducted with the ProTaper Gold rotary file system up to F2 for mesial canals.
Study NCT06237985 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: OneShape file system
Description: According to the manufacturers ' instructions, root canal treatments will be conducted with the OneShape rotary file system up to 25/.06 for mesial canals.
Study NCT06237985 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TruNatomy file system
Description: According to the manufacturers ' instructions, root canal treatments will be conducted with the TruNatomy rotary file system up to 26/.04 for mesial canals.
Study NCT05799885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuro-vestibular-ocular group
Description: Neuro-vestibular-ocular exercise group (30 footballers)will do the exercises given in addition to their training
Study NCT05799885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial Release group
Description: Manual myofascial release will be applied by the physiotherapist.(30 football players)
Study NCT05652439 — intervention group
Intervention type: OTHER
Intervention: Observational retrospective data collection
Description: Observational retrospective data collection of the incidence of adverse cardiovascular and cerebrovascular outcomes
Study NCT05704582 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Avatar Intervention
Description: 8 weekly sessions of 60 minutes. Possibility of 4 additional sessions.
Study NCT05704582 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Addiction supportive intervention
Description: 8 weekly sessions of 60 minutes. Possibility of 4 additional sessions.
Study NCT06373965 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online to offline counseling
Description: * Online registration and risk assessment: Users complete an onboarding process comprised of creating an account, entering demographic data, customizing settings, and completing the baseline risk assessment.~* HIVST kit order, management, and monitoring: The platform will allow users to request HIVST kits via standard mail or self-pickup at user-preferred sites (e.g., LGBT-friendly clinics). After completing the mandatory section of the questionnaire and selecting a delivery option, a random personal identification number will be assigned by the system, which will be used to track future HIVST requests, collect HIVST results, and monitor subsequent linkage to further testing and HIV care.~* eHIVST and O2O linkage to HIV clinical services: After unsealing the test kit, participants will find a reminder card to schedule their O2O pre- and post-test e-counseling appointment.
Study NCT06373965 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online to offline counseling
Description: * Online registration and risk assessment: Users complete an onboarding process comprised of creating an account, entering demographic data, customizing settings, and completing the baseline risk assessment.~* HIVST kit order, management, and monitoring: The platform will allow users to request HIVST kits via standard mail or self-pickup at user-preferred sites (e.g., LGBT-friendly clinics). After completing the mandatory section of the questionnaire and selecting a delivery option, a random personal identification number will be assigned by the system, which will be used to track future HIVST requests, collect HIVST results, and monitor subsequent linkage to further testing and HIV care.~* eHIVST and O2O linkage to HIV clinical services: After unsealing the test kit, participants will find a reminder card to schedule their O2O pre- and post-test e-counseling appointment.
Study NCT05610345 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Placental Blood Drainage
Description: Immediately after vaginal delivery following delayed cord clamping and cutting of the cord, the cord will be unclamped and blood will be drained from the placenta until cessation of flow.
Study NCT06432608 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: fermented milk, Yakult
Description: Study subjects will be provided with a product based on fermented milk, Yakult (80mL) daily for four weeks in order to know the effects of clinical manifestation of functional constipation and short-fatty acids in the Mexican population
Study NCT05428761 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TP1
Description: Participants will receive TP1 during one experimental visit.
Study NCT05428761 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TP2
Description: Participants will receive TP2 during one experimental visit.
Study NCT05428761 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive placebo during one experimental visit.
Study NCT05610345 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Placenta Blood Not Drained
Description: Placenta Blood Not Drained
Study NCT05257031 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SmofKabiven extra Nitrogen
Description: SmofKabiven extra Nitrogen contains amino acids (Aminoven®), glucose, lipids (SMOFlipid®: 30% soybean oil, 30% medium-chain triglycerides, 25% olive oil, 15% fish oil), and electrolytes.
Study NCT04656925 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency management
Description: Reinforcement, or incentives, in exchange for evidence of not drinking alcohol.
Study NCT06225934 — intervention group
Intervention type: BEHAVIORAL
Intervention: Exercise and home program to increase lateral flexion and rotation angles
Description: Suggestions will be made to the parent/caregiver of the baby diagnosed with congenital muscular torticollis (CMT) participating in the study to increase the baby's decreasing lateral flexion and rotation angles, and parents/caregivers will be advised to integrate these suggestions into their daily routine as much as possible.These suggestions; It includes holding-carrying-breastfeeding (feeding) principles, active-passive lateral flexion and active stretching of the child and activities that will increase joint range of motion for the SCM muscle, environmental arrangements, games that enable the development of active symmetrical movements and prone activities. The home program to be implemented by parents/caregivers will continue for 6 weeks. During the evaluations, the demographic characteristics of the babies (gender, gestational age, birth weight, parental information, mother's pregnancy type, pregnancy history, Apgar score, ultrasonography values, etc.) will be recorded.
Study NCT04259645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: Bupivacaine 0.375% 20 mL
Description: 20 mL 0.375% Bupivacaine
Study NCT04259645 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Drug: Bupivacaine 0.375% diluted to 0.1875%
Description: Each block of 0.375% Bupivacaine x 20 ml mixed (diluted) with Normal Saline Solution 20 mL (total 40 mL)
Study NCT04832425 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PRAX-114
Description: 40 mg once daily
Study NCT04832425 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo once daily
Study NCT06125041 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebelizumab+Carboplatin+Etoposide+Concurrent Radiotherapy
Description: Eligible patients will receive the following treatment schemes: adebelizumab+carboplatin+etoposide, with one treatment cycle every three weeks. After 4-6 cycles, adebelizumab maintenance therapy combined with concurrent radiotherapy will be given, and conventional radiotherapy will be given to chest lesions (2Gy\*(20-30)f), brain (3Gy\*10f)/ bone (3Gy\*10f)/ adrenal gland. Immunotherapy is suspended during radiotherapy for chest lesions and lymph nodes in mediastinum, and immunotherapy is given 1-2 weeks after radiotherapy. Radiotherapy for other metastatic lesions can be carried out simultaneously with immunotherapy.
Study NCT06293599 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: scapular stabilization exercises
Description: the patients will receive scapular stabilization exercises in the form of scapular orientation exercises,Forward/Backward Bear Crawls,Lateral Bear Crawls and assisted stretch for pectoralis minor
Study NCT06293599 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality exercises
Description: The exercises described were done in a consistent manner, emphasizing low intensity, and using lightweight dumbbells (range, 3 to 30 pounds). The weight of the dumbbell was individually selected by the subject for each exercise.~1. elevation of the arm in the sagittal plane (shoulder flexion~2. elevation of the arm in the scapular plane with humeral external rotation (shoulder scaption~3. elevation of the arm in the coronal plane (shoulder abduction)~4. rowing~5. horizontal shoulder abduction~6. horizontal abduction with humeral external rotation~7. push-up with hands apart~8. push-up with a plus-normal push-up adding maximum shoulder and scapular protraction with elbows fully extended~9. dumbbell bench press~10. dumbbell military press~11. shoulder shrug~12. deceleration exercise-simulating the pitching followthrough~13. shoulder extension prone~14. shoulder internal rotation~15. shoulder external rotation~16. press-up
Study NCT06293599 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: regular routine exercises
Description: the patients will receive routine exercises in the form of Sleeper Stretch: Posterior Capsular Stretch, Push up, Wall slides, Kettlebell High Pull,
Study NCT06293599 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: regular routine exercises
Description: the patients will receive routine exercises in the form of Sleeper Stretch: Posterior Capsular Stretch, Push up, Wall slides, Kettlebell High Pull,
Study NCT06402656 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Customized facemask
Description: The customized face mask will be fabricated from a 3D digital image of the patient's face obtained by means of a 3D scanner. Such a scanner consists of 6 digital SLR cameras and software capable of processing a 3-D image of the patient's face exportable as an stl file.
Study NCT06402656 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard facemask
Description: The standard facemask is the commercially available Petit standard facemask
Study NCT05703711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mHealer
Description: MHealer is a software application installed on smartphones that provides psychosocial treatment support and patient condition tracking.
Study NCT06370806 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weight loss and lifestyle intervention
Description: Interdisciplinary intervention addressing weight loss and lifestyle change including nutritional behavior change, aerobic exercise, sleep hygiene, and alcohol and tobacco cessation combined with usual care (i.e., CPAP)
Study NCT04407871 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture and Chinese Herbal Medicine
Description: 1) acupuncture and CHM, 2) acupuncture and placebo CHM, 3) control acupuncture and CHM or 4) control acupuncture and placebo CHM by an interactive online computer program in a central office. Using a 1:1:1:1 treatment ratio, there will be 682 women assigned to each treatment group.
Study NCT04407871 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Acupuncture and Chinese Herbal Medicine
Description: 1) acupuncture and CHM, 2) acupuncture and placebo CHM, 3) control acupuncture and CHM or 4) control acupuncture and placebo CHM by an interactive online computer program in a central office. Using a 1:1:1:1 treatment ratio, there will be 682 women assigned to each treatment group.
Study NCT01452698 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-438
Description: TAK-438 20 mg, tablets, orally, once daily for up to 8 weeks.
Study NCT01452698 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Lansoprazole placebo-matching capsules, orally, once daily for up to 8 weeks.~For participants whose EE is not endoscopically healed at Week 8, the participants will receive additional treatment of TAK-438 40 mg, tablets, orally, once daily for up to an additional 8 weeks.
Study NCT01452698 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lansoprazole
Description: Lansoprazole 30 mg, capsules, orally, once daily for up to 8 weeks.~For participants whose EE is not endoscopically healed at Week 8, the participants will receive additional treatment of TAK-438 40 mg, tablets, orally, once daily for up to an additional 8 weeks.
Study NCT05384444 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fasting mimicking diet
Description: The fasting mimicking diet consists of a 5 day regimen: day 1 diet of the diet supplies \~1000 kcal (10% protein, 56% fat, 34% carbohydrate), day 2-5 are identical in formulation and provide 800 kcal (9% protein, 44% fat, 47% carbohydrate). At least 4 cyclic FMDs will be performed after operation.
Study NCT06384638 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: topical application of coconut oil
Description: topical application of coconut oil
Study NCT06384638 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: scaling and debridement
Description: scaling and debridement
Study NCT04883437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Given PO
Study NCT04883437 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Given IV
Study NCT04883437 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT04883437 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05050916 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: This is a Phase II randomized, dose-ranging clinical trial including 1) a within-woman comparison of hormones pre-and post-supplementation and 2) a comparison across women on a Vitamin D and a placebo. After recruitment, there will be two phases: Phase 1 will follow all women for one menstrual cycle prior to supplementation; blood will be assayed for 25OHD. Phase 2 includes only: 1) women with less than 20 ng/ml 25OHD (deficient) OR 2) a sample of women with >20 ng/ml 25OHD (sufficient) as the placebo group. During Phase 2, deficient women will be assigned to receive a blinded dose of 50,000 IU of vitamin D supplementation per week and followed for three more menstrual cycles. Hormone levels will be compared between the pre-and post-supplementation cycles as the primary analysis. The primary aim will test: if mid-luteal progesterone, rate of estrogen rise and pre-ovulatory LH are higher in vitamin D supplemented cycles.
Study NCT05050916 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Vitamin D
Description: This is a Phase II randomized, dose-ranging clinical trial including 1) a within-woman comparison of hormones pre-and post-supplementation and 2) a comparison across women on a Vitamin D and a placebo. After recruitment, there will be two phases: Phase 1 will follow all women for one menstrual cycle prior to supplementation; blood will be assayed for 25OHD. Phase 2 includes only: 1) women with less than 20 ng/ml 25OHD (deficient) OR 2) a sample of women with >20 ng/ml 25OHD (sufficient) as the placebo group. During Phase 2, deficient women will be assigned to receive a blinded dose of 50,000 IU of vitamin D supplementation per week and followed for three more menstrual cycles. Hormone levels will be compared between the pre-and post-supplementation cycles as the primary analysis. The primary aim will test: if mid-luteal progesterone, rate of estrogen rise and pre-ovulatory LH are higher in vitamin D supplemented cycles.
Study NCT04761302 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Use of non-steroid anti-inflammatory drugs (NSAIDS) as an alternative for post-operative pain management after a femur and tibia fracture
Description: This is a randomized controlled, single blind, parallel groups, opioid control trial of all patients (total of 150 patients) who suffered tibial and femoral shaft fractures and were treated with intramedullary nailing. Patients will be aleatory assigned to two study groups: Group-1 will receive non-opioid medications, and Group-2 will receive opioid medications. During the inpatient postoperative period, patients will undergo subjective evaluation of pain utilizing a previously validated questionnaire, the Visual Analogue Score (VAS). The first questionnaire will be completed twelve hours after surgery and during subsequent twelve-hour intervals until discharge. Secondary outcomes will include efficiency such as time to gastrointestinal motility, time to weight bearing of affected limb, resumption of ambulation, and length of hospital stay. The evaluation will take approximately 15 minutes to complete each time, we the entire participation time to be 60 minutes.