AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06025292 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lean Pork vs Plant-Based Protein
Description: Participants will eat prepared study meals for three days that have either protein sourced from lean pork or plant-based sources.
Study NCT05606822 — intervention group
Intervention type: OTHER
Intervention: Observational
Description: Collection of data from electronic health record
Study NCT04740593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Orthoptic care with the prescription of glasses from age 12-18 months onwards
Description: Children assigned to the intervention group (group 1) will receive orthoptic care, including exams 1-3 (depending on the refractive error) times a year, and glasses, based on accurate determinations of refractive error by retinoscopy in cycloplegia by the study orthoptists at age 12-18 months. The spectacles for the children in this study will be provided by the study via their optician without costs.
Study NCT04740593 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Orthoptic care without the prescription of glasses from age 12-18 months onwards
Description: Children with high refractive error in the control group (group 2) will also receive orthoptic care, including exams 1-3 (depending on the refractive error) times a year, but they will not receive glasses.
Study NCT04740593 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: First measurement only
Description: Children who have no or mild refractive error (group 3), the majority of all children, will be examined by the study orthoptists only once at the age of 12-18 months, after which youth health care (YHC) physicians and nurses will continue standard vision screening at CHCs, as part of screening for general health disorders and vaccinations. Visual acuity is measured routinely at 42-48 months as part of standard vision screening.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: One dose group
Description: The vaccines are to be administrated at day 0. Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: One dose group
Description: The vaccines are to be administrated at day 0. Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Two doses group
Description: The vaccines are to be administrated at day 0 and 28. Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Two doses group
Description: The vaccines are to be administrated at day 0 and 28. Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Aged 18-59 years
Description: The vaccines are to be administrated in the population of 18-59 years.Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05609019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYHX2005
Description: Tablets. Take orally.
Study NCT05674968 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Managing Challenging Behaviors in ADHD; Psychosocial program
Description: MCB-ADHD is a brief Behavioral Parent Training (BPT) program delivered to caregivers and children together. THe researchers have specially designed this program to be flexible so that it can be delivered over telehealth and/or in-person. All sessions are guided by web-based tool to provide parent support materials and direct the work to be completed in session. MCB-ADHD combines brief BPT skills modules adapted from an established evidence-based BPT called Helping the Noncompliant Child (HNC; McMahon \& Forehand, 2003) with high quality psychoeducation and advocacy training that were developed by the investigators specifically for use in this project. Families receive 4 sessions adapted from HNC focused on behavior management and 2 sessions focused on education and empowerment.
Study NCT05441475 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABSK-011 180 mg QD combined with atilizumab 1200 mg q3w
Description: All subjects will receive continuous oral administration of absk-011 once a day (QD) or twice a day (bid) with an initial dose of 180 mg, and intravenous infusion (IV) of 1200 mg of atilizumab every 21 days (q3w).
Study NCT05470062 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: arch support insoles (FootDisc)
Description: The FootDisc insole is designed with curEVA for shock absorption and motion reduction, poron for secondary heel and metatarsal protection, and dynamic arch support for returning energy for propulsion
Study NCT06438393 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: CT coronary angiography and non-contrast CT
Description: A CTCA is an X-ray computed tomography of the coronary arteries that allows visualization of coronary plaques with high temporal and spatial resolution, however, it implies the use of iodine contrast and exposition to clinically significant ionizing radiation.~Non-contrast ECG-gated CT (calcium score - CCS image). A non-contrast cardiac CT for CCS can be performed very quickly with significantly lower radiation (\~6 times lower) than CTCA and without the need for contrast.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Aged 18-59 years
Description: The vaccines are to be administrated in the population of 18-59 years.Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Aged 60 years old and above
Description: The vaccines are to be administrated in the population of 60 years old and above.Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT05663086 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Aged 60 years old and above
Description: The vaccines are to be administrated in the population of 60 years old and above.Low dose or high dose LYB001 or positve-controlled group will be randomly assigned to receive in a 1:1:1 ratio.
Study NCT06082947 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CliniMACS®
Description: CliniMACS® αβT cell/CD19+B cell depletion device for Children and Young Adults with Hematologic Malignancies undergoing alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)
Study NCT06653010 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Universal CAR-T cells injection for treating mCRC
Description: A novel universal CAR-T platform to treat cancer patients
Study NCT05963425 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: This physical activity program will be based only on the work of basic physical traininig, in which specifically and mainly the strength and resistance will be worked, but also flexibility
Study NCT05963425 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: usual clinical practice
Description: usual clinical practice
Study NCT05011422 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ex Vivo T-cell receptor alpha-beta and CD19+ Depletion using CliniMACs Plus
Description: Once pheresed, the product will be washed to remove platelets and the cell concentration will be adjusted per laboratory and ClinicMACS technology recommendations. It is then labeled using the CliniMACS αβ-TCR Biotin Kit and CD19+ immunomagnetic microbeads. After labeling, the cells are washed to remove unbound microbeads. The partially processed product is loaded on the CliniMACS device where labeled cells are depleted and the negative fraction is eluted off the device. The negative fraction is centrifuged and volume reconstituted to obtain the final product
Study NCT04891250 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin
Description: Treatment of SARS Cov-2 patients with Ivermectin
Study NCT04891250 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prophylaxis
Description: Treatment of high risk population with Ivermectin as prophylaxis
Study NCT05189015 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olmesartan
Description: - Olmesartan group: Olmesartan, 20 (40) mg once a day, oral administration
Study NCT05189015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olmesartan
Description: - Olmesartan group: Olmesartan, 20 (40) mg once a day, oral administration
Study NCT06672380 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote Physical Exercise Program for Breast Cancer Survivors
Description: Structured and remotely guided physical exercise program The participants in the intervention group took part in a remote physical exercise program for 12 weeks. The telepresence sessions, conducted three times a week via Google Meet®, lasted 60 minutes and consisted of three phases: warm-up (10 minutes), multi-joint functional exercises (40 minutes) and stretching (10 minutes). The exercises were progressively intensified over the weeks, using the Borg scale to monitor effort. The intensity was adjusted in three cycles: in the first 4 weeks (60 seconds of exercise/90 seconds of rest), in weeks 5 to 8 (75 seconds of exercise/60 seconds of rest) and in weeks 9 to 12 (90 seconds of exercise/30 seconds of rest).
Study NCT06672380 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Initial Consultation and Exercise Guidance via Ebook for Women Surviving Breast Cance
Description: Participants in the Ebook group received an illustrated manual containing detailed guidelines for practicing simple physical exercises at home, using only their body weight. The manual suggested a frequency of 3 to 5 times a week, with 30 to 60 minutes of activities such as stretching, squats and exercises for the upper and lower limbs. The participants were encouraged to follow these guidelines and, 30 days after receiving the ebook, an additional stimulus was sent by text message, reinforcing the importance of following the protocol.
Study NCT06672380 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Initial Incentive for Eating Habits in Women Surviving Breast Cancer
Description: The control group only received general guidance on the importance of regular physical activity. The recommendations followed health guidelines, suggesting between 150 and 300 minutes of moderate-intensity physical activity per week.
Study NCT06687174 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MY008211A tablets
Description: MY008211A BID
Study NCT06687174 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: MY008211A tablets matched placebo
Description: Matching placebo to MY008211A taken twice a day.
Study NCT06693661 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Kidney Health Coaching
Description: The intervention entails support from a KHC that includes:~* An initial rapport-building call~* Ongoing telephone support at least twice a month for six months~* Meeting the patient at all in-person clinic appointments~* Documenting interactions in the EMR using a customized platform~Telephone support begins with a social determinants of health (SDoH) screening tool to identify barriers and facilitators to CKD self-management and appointment adherence. This tool provides access to local resources based on the patient's ZIP code. Subsequent calls will follow up on resource usage, review CKD educational materials and treatment options, complete the Decision Aid for Renal Therapy tool, and facilitate communication through the patient portal. Each call will start with specific goals (e.g., review National Kidney Foundation CKD materials) and conclude with goals for the next session.
Study NCT06693661 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: ER Discharge (d/c): Patients may receive consultations and support from Care Management in the ER such as transportation or medication assistance. Follow-up by a social worker varies post-discharge.~Hospital d/c: All hospitalized patients are assessed by the care management team to identify psychosocial needs and begin discharge planning, which may include follow-up appointments and resources. High-risk patients receive additional follow-up from a care transitions coordinator for 30 days post-discharge.~Primary Care: Patients in primary care clinics have access to various support services. Those recently hospitalized or identified as high-risk receive care coordination from social workers. Internal referrals are managed by referral coordinators, while external referrals come from clinic staff. Discharge information is provided after visits.~Nephrology: There are no coordinated support services for chronic kidney disease (CKD) patients receiving nephrology care.
Study NCT06435156 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotagliflozin
Description: Sodium-glucose Co-transporter inhibitor
Study NCT06435156 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo
Study NCT06693102 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital intervention targeting cancer-related cognitive impairments
Description: The intervention is developed using a person-centered approach and includes key components such as psychoeducation, cognitive training, compensatory strategy training, and cognitive restructuring exercises. Participants receive weekly remote support from a therapist and are encouraged to complete the program within a six-week period.
Study NCT06693102 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Crossword and sudoku taks
Description: Participants receive crossword and sudoku tasks. They are encourraged to solve such tasks for a minimum of 15 minutes daily for six weeks.
Study NCT06692062 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiation Therapy
Description: R0 resection: 45-50Gy/20-25f R1 resection: 54-56Gy/25-28f R2 resection: 60-70Gy/30-35f
Study NCT06693297 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Immediate loading of early placed implants
Description: Implants with active thread design will be used. The implants placed will be randomly allocated into either immediate loading or conventional loading group.
Study NCT06693297 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Immediate loading of early placed implants
Description: Implants with active thread design will be used. The implants placed will be randomly allocated into either immediate loading or conventional loading group.
Study NCT06693297 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional loading of early placed implants
Description: Definitive loading of early placed implants upon successful osteointegration (after 8 weks)
Study NCT06693297 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional loading of early placed implants
Description: Definitive loading of early placed implants upon successful osteointegration (after 8 weks)
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-383
Description: Intravenous (IV) Infusion
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfilzomib
Description: IV Infusion
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Oral Capsule
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elotuzumab
Description: IV Infusion
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Oral Tablet
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Subcutaneous or IV Injection
Study NCT06158841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Oral Tablet or IV Infusion
Study NCT05845047 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: PICTURE-IT
Description: The speech-language pathologist (SLP) will provide one of the following stimuli hierarchically:~1. Single words depicted in the picture, then with written and spoken labels~2. 2-word phrases depicted in the picture and then with written and spoken word~3. Subject-Verb-Object sentence depicted in the picture and then with written and spoken sentences~4. Two-sentence event, depicted with photos and subsequently with two written and spoken sentences~5. Short story depicted with a video clip and subsequently with printed and spoken narrative.~Sessions will be completed online with a speech-language pathologist using video conferencing software, using a laptop and a hot spot the investigators will provide if needed. Participants in both groups will receive the same 15 45-minute sessions of a PICTURE-IT.
Study NCT05845047 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PICTURE-IT
Description: The speech-language pathologist (SLP) will provide one of the following stimuli hierarchically:~1. Single words depicted in the picture, then with written and spoken labels~2. 2-word phrases depicted in the picture and then with written and spoken word~3. Subject-Verb-Object sentence depicted in the picture and then with written and spoken sentences~4. Two-sentence event, depicted with photos and subsequently with two written and spoken sentences~5. Short story depicted with a video clip and subsequently with printed and spoken narrative.~Sessions will be completed online with a speech-language pathologist using video conferencing software, using a laptop and a hot spot the investigators will provide if needed. Participants in both groups will receive the same 15 45-minute sessions of a PICTURE-IT.
Study NCT05845047 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CoDeLT
Description: The speech-language pathologist (SLP) will facilitate the computer-delivered naming treatment, consisting of a picture/seen and heard spoken word verification task.~A picture will be presented for two seconds on a laptop computer screen and will be immediately followed by an audio-visual display of a speaker's mouth saying a noun. The spoken word either will or will not match the preceding picture, and the participant must indicate whether the picture and video match or do not match. The computer will provide immediate visual feedback following a response.~Sessions will be completed online with a speech-language pathologist using video conferencing software, using a laptop and a hot spot the investigators will provide if needed. Participants in both groups will receive the same 15 45-minute sessions of a PICTURE-IT.
Study NCT05845047 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CoDeLT
Description: The speech-language pathologist (SLP) will facilitate the computer-delivered naming treatment, consisting of a picture/seen and heard spoken word verification task.~A picture will be presented for two seconds on a laptop computer screen and will be immediately followed by an audio-visual display of a speaker's mouth saying a noun. The spoken word either will or will not match the preceding picture, and the participant must indicate whether the picture and video match or do not match. The computer will provide immediate visual feedback following a response.~Sessions will be completed online with a speech-language pathologist using video conferencing software, using a laptop and a hot spot the investigators will provide if needed. Participants in both groups will receive the same 15 45-minute sessions of a PICTURE-IT.
Study NCT05612295 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBPP
Description: MBPP program consist of three fundamental principles (i.e., attention monitoring, acceptance, sport-specific rationale) and six performance-related core mental attributes including three behavioral and three neurocognitive components.~Each session will start with a brief homework discussion and recap of the preceding session, and instructors will deliver a topic-related brief story or group activity to participants, followed by a theoretical introduction and practice of mindfulness. Finally, at the end of each session, instructors will guide participant to discuss mindfulness applications related to specific sports performances. At the end of the session, participants will be assigned homework to increase the effectiveness of MBPP, and participants will be encouraged to practice daily for at least 10-15 min between the sessions.
Study NCT06352190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] SY-5007
Description: Carbon-14 labeled SY-5007
Study NCT05337267 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: sintilimab (after the change)
Description: 0.3mg/kg，I.V.，single dose
Study NCT05337267 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sintilimab (before the change)
Description: 0.3mg/kg，I.V.，single dose
Study NCT05782218 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Almonds
Description: Participants will receive 2.2 oz (62 g) of almonds to ingest within 15 minutes.
Study NCT06491381 — intervention group
Intervention type: PROCEDURE
Intervention: Cesarean delivery
Description: The cesarean section will begin with a Pfannenstiel incision above the pubic bone, followed by blunt dissection to separate tissue layers and retracting the rectus muscles for peritoneal cavity access. A transverse or vertical peritoneal incision will expose the uterus, and a transverse incision on the lower uterine segment will be made for delivery. The baby will be delivered, the umbilical cord clamped and cut, and the baby handed to the pediatric team. The placenta will be detached and delivered, and the uterus will be closed with multiple layers of sutures. The abdominal layers will be closed with absorbable Polyglactin (Vicryl) sutures for the rectus sheath and subcutaneous tissue, and non-absorbable Polypropylene sutures for the skin. A sterile dressing will be applied to protect the wound and promote a clean healing environment, ensuring proper surgical technique, tissue handling, and minimizing post-operative complications.