AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04620343 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: C: Breathing advice with bio-feedback, Speech Therapy
Description: The training period with the speech therapist takes three days, divided into 6 sessions. The training is continued at home, implementing the techniques during physical activity and at rest. The aim of the speech therapy is to help the patients to develop a strategy on how to control his/her larynx during exercise, and to be able to continue exercising without experiencing dramatic EILO incidents. They will be informed that the best approach is to start practicing while performing low to moderate intensity exercise, and then gradually increase the intensity as they become more confident. It will be emphasized that the new breathing technique they are about to adopt will need to be repeated until it becomes adapted as a part of their automated breathing pattern. Patients will be followed up with video meetings one and three weeks after initial training to observe progress.
Study NCT04620343 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: D: Breathing advice with bio-feedback, IMT and Speech Therapy
Description: All treatments as described above.
Study NCT04620343 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: A: If CLE-test unchanged, additional IMT and Speech Therapy
Description: All treatments as described above.
Study NCT04620343 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery 1: Supraglottoplasty - full procedure under general anesthesia
Description: Endoscopic supraglottoplasty with carbon dioxide laser and cold steel microlaryngeal instruments. The patient is intubated with an armored laser-tube which is positioned in the posterior midline to protect this area from laser injury. The laryngoscope is positioned into the vallecula and the surgery is visualized through an operation-microscope. CO2-laser beams of 2-4W focused with micro spot is utilized. Releasing incisions are made at the anterior border of both AEFs. The depth of the incisions are limited to the cranial border of the ventricular folds. The cuneiform tubercles including their surrounding mucosa are removed in a circular pattern before the two incisions are adjoined, thus creating a drop shaped excision. Care is taken to avoid scarring. It is recommended to protect the posterior commissure and the piriform sinus with wet tissue cloths. In case of perioperative edema of the laryngeal mucosa, corticosteroids are administrated to prevent laryngeal edema post-operatively.
Study NCT04620343 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery 2: Supraglottoplasty - mini-invasive procedure under general anesthesia
Description: Endoscopic supraglottoplasty with carbon dioxide laser. The patients are intubated with an armored laser-tube, which is positioned in the posterior midline to protect this area from laser injury. The laryngoscope (Benjamin/Lindholm) is positioned into the vallecula and the surgery is visualized through an operation-microscope. CO2-laser beams of 2-4W focused with micro spot are utilized. Four punctures will be made along the lateral borders of both aryepiglottic folds bilateral, thus creating a row of small punctures parallel to the rim of the aryepiglottic folds. The punctions should not be deeper than the incision in the full procedure (above); i.e. less than 5 millimeter, and care must be taken to avoid heat affecting the nervus recurrens posteriorly. Care is taken to avoid scarring and collateral thermal injury. It is recommended to protect the posterior commissure and the piriform sinus with wet tissue cloths. No antibiotic prophylaxis is administered.
Study NCT06100081 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Detection of lesions using fluorescence molecular imaging
Description: Using a fluorescence camera, lesions will be detected and biopsies will be taken to try and find cancer of unknown primary
Study NCT05202392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial release with isometric exercises
Description: Patients in group A will receive 40 minutes of combined therapy treatment session including myofascial release of muscles with trigger point release and 5 isometric exercises of neck at alternative 3 days/week for 4 weeks.
Study NCT05202392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial release with scapular stabilization exercise
Description: Patients in group B will get 40 minutes of myofascial therapy same as the first group combined with scapular stabilization exercise in 5 different positions and this treatment session will be at alternative 3 days/week for 4 weeks.
Study NCT05297006 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: The infants who drank milk powder were given a dietary intervention four months before
Description: The infants who eat milk powder were randomly divided into two groups: group containing new compound functional ingredients and group without new compound functional ingredients
Study NCT04162938 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient-Centered Electronic App
Description: The coordinator will enter lab information to generate the patient's Fibrosis-4 score for liver fibrosis staging. With the information of liver fibrosis staging and survey responses, the app will generate individualized reports of the participant's comprehensive HCV disease progression, knowledge, and level of interest in receiving HCV care. The app will then deliver a streamlined, tailored, brief education message and include information regarding services and assistance for receiving HCV care.
Study NCT05183464 — intervention group
Intervention type: BIOLOGICAL
Intervention: saliva samples
Description: Collection of salivary a-amylase during the day (5 times a day: at 8:00 am, 9:00 am,1:00pm, 4:00pm and 8:00pm) with Salivette.
Study NCT05183464 — intervention group
Intervention type: BEHAVIORAL
Intervention: Stanford sleepiness scale
Description: The Stanford Sleepiness Scale evaluates sleepiness at the time of the evaluation. The subjects have to choose the statement best representing their level of sleepiness on a scale ranging from 1 to 7: the higher the score, the higher the sleepiness.~This scale will be submitted to the children before each salivary sampling (5 times a day: at 8:00 am, 9:00 am,1:00pm, 4:00pm and 8:00pm)
Study NCT05183464 — intervention group
Intervention type: BEHAVIORAL
Intervention: Karolinska Sleepiness Scale
Description: The Karolinska Sleepiness Scale assesses the perceived level of sleepiness at the time of the evaluation on a 9-points scale. The higher the score, the higher the sleepiness.~This scale will be submitted to the children before each salivary sampling (5 times a day: at 8:00 am, 9:00 am,1:00pm, 4:00pm and 8:00pm)
Study NCT05183464 — intervention group
Intervention type: BEHAVIORAL
Intervention: Epworth Sleepiness Scale
Description: The Adapted Epworth Sleepiness Scale for children in which the item falling asleep while in a car stopped in traffic was replaced by falling asleep at school assesses the risk of falling asleep in 8 daily-life situations estimated on a 4-point Likert scale. The total score is the sum of the scores for the 8 items: a higher score represents greater sleepiness and the pathological threshold is higher than 10.~This scale will be submitted to the children one time, at the onset of the hospitalization.
Study NCT05183464 — intervention group
Intervention type: BEHAVIORAL
Intervention: BLAST test
Description: The BLAST (Bron/Lyon Attention Stability Test) is a computerized attention test evaluating brief lapses of attention with 4 measures: reaction times, errors and two composite measures (Stability and Intensity). The subjects have to detect the presence or the absence of a specific stimulus during approximatively 60 trials for 3 minutes. Normative data are available for both children and adults.~This test is part of the neuropsychological evaluation, conducted the afternoon of the first day of hospitalization. The test is realized at 4:00pm.
Study NCT05271721 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: epidural transforaminal injection of magnesuim sulfate
Description: transforaminal fluroscopic guided
Study NCT05271721 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: epidural transforaminal injection of dexmedtemodine
Description: transforaminal fluroscopic guided
Study NCT05271721 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: transforaminal epidural injection of dexamethasone
Description: transforaminal fluroscopic guided
Study NCT04220619 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Tranesophageal Echocardiography
Description: RescueTEE during ACLS versus Conventional ACLS
Study NCT04766723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NT 201
Description: Active ingredient: Clostridium Botulinum neurotoxin Type A free from complexing proteins. Solution for injection prepared by reconstitution of powder with 0.9% Sodium Chloride (NaCl).
Study NCT04766723 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: NT 201
Description: Active ingredient: Clostridium Botulinum neurotoxin Type A free from complexing proteins. Solution for injection prepared by reconstitution of powder with 0.9% Sodium Chloride (NaCl).
Study NCT04766723 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Solution for injection prepared by reconstitution of powder with 0.9% Sodium Chloride (NaCl).
Study NCT05944939 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical extraction of impacted third molar
Description: After surgical extraction of mandibular impacted teeth concentrated growth factor placed in socket closure done with help of silk 3.0 suture
Study NCT05213299 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: AURICULAR ACUPUNCTURE
Description: Auricular acupuncture is a method for diagnosing and treating physical and psychosomatic dysfunctions by stimulating a specific point in the ear. To conducting this intervention, the investigators use press tack needles to perform auricular acupuncture.
Study NCT05213299 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PLACEBO
Description: For this intervention, instead of needles, the investigators use four pieces of tape.
Study NCT06327412 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercise on the treadmill
Description: According to the cardiopulmonary exercise (CPET) test, 40 minutes (5 minutes warm-up, 30 minutes exercise, 5 minutes cool-down) at an exercise intensity of 50-60% of the VO2 max (the maximum amount of oxygen that an individual can utilize during intense or maximal exercise) level recorded individually in patients, 5 days a week for 4 weeks.Both patient groups will be given lymphedema-specific remedial exercise program training. Anatolian Lymphedema Association lower extremity lymphedema exercise sheets will be delivered to the patients in writing, and training on exercise practices will be given face to face as a session by a physiotherapist at the physical therapy lymphedema outpatient clinic. Patients will be asked to perform these exercises daily as stated in the leaflet and in the number of repetitions. Patients will be given an exercise diary to ensure their compliance with exercise and will be asked to mark this form daily
Study NCT05842551 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: SHAM_COMPARATOR
Intervention: Prismatic adaptation and electric stimulation
Description: Combinatory effect of tEs and prismatic lenses in the experimental group and of sham stimulation and prismatic lenses in control group
Study NCT05842551 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Prismatic adaptation and electric stimulation
Description: Combinatory effect of tEs and prismatic lenses in the experimental group and of sham stimulation and prismatic lenses in control group
Study NCT06327412 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Walking between 12-13 RPE (The Borg Rating of Perceived Exertion) according to the Modified Borg Scale
Description: He/she will be asked to walk 40 minutes a day, 5 days a week, for 4 weeks. Training will be given for the first session in the hospital to ensure that the patient's walking pace is between 12-13 RPE according to the Modified Borg scale.Both patient groups will be given lymphedema-specific remedial exercise program training. Anatolian Lymphedema Association lower extremity lymphedema exercise sheets will be delivered to the patients in writing, and training on exercise practices will be given face to face as a session by a physiotherapist at the physical therapy lymphedema outpatient clinic. Patients will be asked to perform these exercises daily as stated in the leaflet and in the number of repetitions. Patients will be given an exercise diary to ensure their compliance with exercise and will be asked to mark this form daily.Treatment compliance will be increased by making weekly phone calls to patients in order to increase treatment compliance and evaluate compliance.
Study NCT05030844 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IMB model based Diabetes Education and Motivational Interviewing
Description: IMB model-based interventions were applied to the intervention group for 3 month. For the information component of the IMB model, diabetes education consisting of four sessions was given in groups of five in the first two weeks. Each patient was given a Diabetes Management Education Booklet prepared by the researchers. For the motivation component of the IMB model, total 5 sessions 30-minute motivational interview was made with individual Whatsapp calls once every two weeks starting from the third week.
Study NCT05571410 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HTN Chat bot
Description: Remote monitoring via automated messaging program
Study NCT05120076 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone 4 Mg/mL Injectable Solution
Description: s. arm/group description
Study NCT05120076 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: NaCl 0.9%
Description: s. arm/group description
Study NCT06420531 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Human milk
Description: maternal breastmilk or donor breastmilk
Study NCT06420531 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Human milk
Description: maternal breastmilk or donor breastmilk
Study NCT00240799 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: acetaminophen extended release
Study NCT00240799 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Study NCT05447572 — intervention group
Intervention type: OTHER
Intervention: FIT + FC
Description: FIT + FC
Study NCT06238570 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gavi, Merck® (automated vitrification instrument)
Description: This instrument recently appeared on the market and demonstrated a high effectiveness in terms of processing time and reproducibility for embryo vitrification. To date, no study has analyzed the efficiency of this automated vitrification instrument on oocyte vitrification.~The oocytes will be stored in closed cassettes in liquid nitrogen
Study NCT06238570 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Vitrolife system
Description: The oocytes vitrification will be carried out by an authorized technician according to the manual protocol validated and used routinely.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Irinotecan
Description: Irinotecan 150 mg/m2 IV over 90 minutes on Day 1 and 15.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: Irinotecan 150 mg/m2 IV over 90 minutes on Day 1 and 15.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin HAI
Description: Oxaliplatin 85 mg/m2 over 3 hours will be administered through the HAI pump on day 1. Oxaliplatin 85 mg/m2 IV over 3 hours on day 15.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Floxuridine
Description: 0.12 mg/kg/day floxuridine (FUDR) and 25 mg dexamethasone in normal saline to a total volume of 300 ml will be administered through the HAI pump.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Leucovorin
Description: Leucovorin 200mg/m2 IV on Day 1 and 15.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5-FU
Description: 5-FU 2400mg/m2 CIV in 46h on Day 1 and 15.
Study NCT03678428 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: Oxaliplatin 85 mg/m2 IV over 3 hours on Day1 and 15.
Study NCT06352684 — intervention group
Intervention type: DEVICE
Intervention: CadAI-B for Breast
Description: CadAI-B for Breast is designed to assist healthcare professionals in lesion detection and differential diagnosis during breast US examinations.
Study NCT03537495 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linezolid
Description: Overall, there is an urgent need for improvement of TBM treatment. LInezolid is known to be well-penetrated to blood brain barrier. A combination of high-dose rifampicin and linezolid as an intensified add-on therapy in the management of TB meningitis has never been studied.~The goal is to assess the most appropriate dose of linezolid for larger follow-up studies and to evaluate the feasibility of a linezolid-containing TBM regimen.
Study NCT06194552 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NTRX-07
Description: Investigational orally administered CB2 agonist
Study NCT06194552 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo administered orally
Study NCT05916898 — intervention group
Intervention type: DEVICE
Intervention: PCI with support of Shockwave Intravascular Lithotripsy
Description: Coronary artery angioplasty of the primary lesion or optimization of the previously implanted stent with the support of Shockwave Intravascular Lithotripsy device
Study NCT06308471 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baby massage was applied to the intervention group (n=20) of the study
Description: The application was applied for 15 minutes every day for ten days, and oral feeding trials were video recorded. Feeding videos were evaluated by expert neonatal nurses using The Oral Feeding Scale without knowing the application group of the babies.
Study NCT06308471 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral stimulation
Description: The application was applied for 15 minutes every day for ten days, and oral feeding trials were video recorded. Feeding videos were evaluated by expert neonatal nurses using The Oral Feeding Scale without knowing the application group of the babies.
Study NCT06197984 — intervention group
Intervention type: PROCEDURE
Intervention: ERCP
Description: ERCP will serve as the exclusive therapeutic modality, aided by a therapeutic duodenoscope to access the common bile duct using a guidewire.
Study NCT06419998 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group A: Pure transanal endorectal pull-through (TAERPT)
Description: Patients of Group A will be treated totally by pure transanal endorectal pull-through without the assistance of laparoscopy
Study NCT06419998 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group B: Laparoscopic-assistance endorectal pull-through (LAERPT)
Description: Patients of Group B will be treated transanal endorectal pull-through but with the assistance of laparoscopy
Study NCT06263764 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Listening to Qur'an Recital
Description: Listening to Surah Ar Rahman twice a day for minimum 15 minutes each for 40 days
Study NCT06370052 — intervention group
Intervention type: PROCEDURE
Intervention: excision
Description: excision of the affected area
Study NCT06113887 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: psychoeducation based on acceptance and commitment therapy
Description: Acceptance and Commitment Therapy Based Psychoeducation will be applied to the patients in the intervention group in the form of group education (consisting of 5-7 people), one session per week for eight weeks; no intervention will be applied to the control group.
Study NCT06200129 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: sws grade 1
Description: Blood for zonulin level was drawn from the group of patients with typical white lesions in the duodenum, called grade 1.
Study NCT06200129 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: sws grade 2
Description: Blood for zonulin level was drawn from the group of patients with typical white lesions in the duodenum, called grade 2
Study NCT06200129 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: control
Description: Group of patients without scattered white lesions in the dueodenum on endoscopy.
Study NCT04916587 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Implementation Strategy of ACEs Screenings
Description: We will use implementation mapping, guided by the EPIS framework, to promote a co-created process and refine the strategy comprised of online training videos, a customized ACEs algorithm and use of technology to improve workflow efficiency, implementation technical assistance/coaching, and written implementation protocols.
Study NCT04916587 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: The ACEs Aware policy goal is to equip providers with training and clinical protocols to screen children and adults for ACEs, detect ACEs early, and connect patients to interventions, resources, and other support to improve patient health and well-being. ACEs screenings are comprised of: a) a 2-hour on-line provider training; b) the Pediatric ACEs and Related Life-events Screener or PEARLS tool; c) an ACEs associated health conditions checklist; and d) complete a wellness exam. The primary care provider uses multiple sources of information to identify a child's need for follow-up services.
Study NCT05613387 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZP8396
Description: Part 1: Participants will receive 6 once-weekly doses of ZP8396 given subcutaneously (s.c., under the skin). Dose level will depend on the cohort.~Part 2: Participants will receive 16 once-weekly doses of ZP8396 given subcutaneously (s.c., under the skin). Dose level will depend on the cohort. Dose up-titration will be used.