AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06357143 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: REMOVE
Description: INITIAL STAGE:~* Aim: Recover mobility~* Exercises: Passive therapy, isometric exercises focused on middle deltoid.~* Goal: 80º passive flexion, 45º abduction, 5 N of abduction force STRENGTHENING STAGE~* Aim: Enhance scapulohumeral rhythm and strength rotator cura~* Exercises: Active-assisted therapy, isotonic exercises between 45-90º of forward flexión and abduction with dumbbells and isometric exercises focused on internal and external rotation.~* Goal: 100º passive flexion, 90º lateral abduction, 10 N of abduction force INTENSIVE STAGE~* Aim: Improve motor control and increase cross-sectional muscular área~* Exercises: Rowe with resistance band, wall push ups, lateral elevation with dumbbles, active external and internal rotation.~* Goal: 15 N of abduction force FUNCTIONAL STAGE~* Aim: Develope daily life activities~* Exercises: Overhead tasks, rowe with Kettlebell, internal and external rotations with resistance bands~* Goal: 20 N of abduction force
Study NCT06357143 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CONTROL
Description: Patients will undergo standard care which consists of an initial consultation with the physiotherapist to receive some recommendations about exercises, progression and health education
Study NCT06570551 — intervention group
Intervention type: DEVICE
Intervention: i3 CGM(continuous glucose monitor)
Description: The i3 CGM consists of a Sensor Pack (including probe, iCGM-S3), a Transmitter Pack (iCGM-t3), and an application (iCGM-APP (released version: V02)).application (i3 CGM App). The user can view their glucose data on the i3 CGM App running on a compatible mobile device.
Study NCT05507437 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TIN816 70 mg lyophilisate powder
Description: Recombinant human CD39 enzyme
Study NCT05507437 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% sterile sodium chloride solution
Study NCT06077513 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CAD-CAM designed and preprinted Ti-Mesh frame
Description: CAD-CAM technology which is the process of designing and manufacturing a custom-made dental device, or a patient-specific dental device from an industrialized product, with the aid of a computer.will be used to plan and preprint a 3-D Ti-Mesh frame prior to the surgery.
Study NCT06077513 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional chairside fabrication of Ti-Mesh frame
Description: A three-dimensional frame or cage of Ti-Mesh or Ti-reinforced d-polytetrafluoroethylene (PTFE) will be fashioned during the surgery to contain, shape and stabilize the bone graft materials (the internal scaffold). This 3-D frame will be custom fabricated from a perforated Ti Mesh sheet material at the time of surgery which takes considerable time and skill.
Study NCT05838573 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin treatment
Description: Participants assigned to the metformin group will receive 500mg metformin three times daily (tid) for 24 weeks. The initial dose will be 500 mg orally in the evening for the first two days, followed by an increase to 500mg twice a day for the subsequent two days. By day 5, the dosage will be further increased to 500mg tid. The highest tolerated dosage will be maintained for participants who could not tolerate the maximum dosage.
Study NCT05910424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: collection of saliva, gum fluid and/or dental plaque samples
Description: Non-invasive sampling of dental plaque, crevicular fluid and/or saliva, using an examination probe, paper tips and saliva swabs
Study NCT05838573 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo treatment
Description: Parallel-dose adjustments will be made for the placebo group to maintain consistency in dosing between the two groups.
Study NCT05838573 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baseline assessments
Description: Schizophrenic participants who don't meet any of the diagnostic criteria for metabolic syndrome will only accept baseline evaluations.
Study NCT05838573 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Volunteer assessments
Description: Apart from psychiatry scales(Hamilton Depression Scale, Young Mania Rating Scale and Self-reporting Inventory-90), other assessments for the healthy subjects are the same as the baseline for sczhiophrenic participants.
Study NCT06583590 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Botulinum toxin A
Description: Botulinum toxin (BoNT) is One of the most potent toxins known to humans produced by Clostridium botulinum that has been used to treat several striated and smooth muscle disorders. Because the pathophysiology and the reason for patients' lack of response to PDE5I is insufficient smooth muscle relaxation and veno-occlusive disorder (VOD) , BTX-A may prove to be a viable treatment for this patient population due to its availability to facilitate long-acting cavernosal smooth muscle relaxation by inhibition of the release of noradrenaline from the adrenergic neurons acting on the cavernosal smooth muscle. Thus, the dominant sympathetic basal tone of the cavernosal smooth muscle is essentially removed, facilitating the occurrence of an erection.
Study NCT06583590 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Tadalafil 5mg
Description: Tadalafil is one of 5-phosphodiesterase inhibitors that used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, tadalafil works by increasing blood flow to the penis to help a man get and keep an erection.Tadalafil is also used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night). Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder.
Study NCT05588141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zotiraciclib
Description: Zotiraciclib will be given orally at the DL1, DL-1, or DL 2 once a day on days 1, 4, 8, 11, 15, 18 of every 28-days cycle (18 cycles total).
Study NCT06352294 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Core stability training
Description: Before starting core stabilization exercises, hotpack will be given for 15 minutes in the warm-up phase, TENS application, then craniocervical flexion training will be given. Core stabilization exercises consist of three stages: easy, medium and difficult
Study NCT06352294 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Core stability training and myofascial relase
Description: Before starting core stabilization exercises, hotpack will be given for 15 minutes in the warm-up phase, TENS application, then craniocervical flexion training will be given. Core stabilization exercises consist of three stages: easy, medium and difficult. In addition, myofascial relaxation will be applied with roller bar along the superficial back line.
Study NCT06056674 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: U-PEACE Intervention
Description: This program will involve about 13 group sessions, with each group session lasting approximately 40-50 minutes. The program session will be held about 2 times a week during the school day (e.g., lunch time) if the group meets in person, or at a pre-scheduled time every week if the group meets online via Zoom.~Participants will learn how to better understand emotional experiences and use this understanding to embrace agency in challenging situations. Participants will develop skills to better deal with emotions by increasing awareness of what is happening in different settings and choose how to respond. Skill-building exercises may include mindfulness practices, flexible thinking, behavioral activation, problem-solving, and exposure activities.
Study NCT06056674 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SAU
Description: Participants in this group will continue to receive standard of care within their school clinic.
Study NCT05887323 — intervention group
Intervention type: DEVICE
Intervention: Implantation of the Tendril 2088 lead in the LBBA
Description: Conduction system pacing is achieved by delivering a pacing stimulus to the Left Bundle Branch area of the heart with Abbott's Tendril 2088 lead.
Study NCT05919849 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief online writing intervention
Description: Participants will be instructed to write for 20 minutes across 3 consecutive days. They will be writing based on the prompts given to them.
Study NCT05919849 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control condition
Description: Participants will be instructed to write in order to control for time and writing engagement.
Study NCT05724173 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: BrainGate Neural Interface System
Description: Placement of the BrainGate2 sensor(s) into the speech-related cortex
Study NCT06544928 — intervention group
Intervention type: DEVICE
Intervention: RESP Biosensor
Description: The RESP Biosensor will be placed on the patient for periodic recording of auscultory sound.
Study NCT05824351 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tanzanian beeswax-pine resin
Description: Thin ring of adhesive in the form of a Tanzanian beeswax-pine resin formula.
Study NCT05824351 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Domestic beeswax-pine resin
Description: Thin ring of adhesive in the form of a domestic beeswax-pine resin formula.
Study NCT05824351 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hollister's AdaptTM Barrier Rings
Description: Thin ring of adhesive in the form of Hollister's AdaptTM Barrier Rings.
Study NCT05953350 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 600mg bid dose of hydroxychloroquine combined with three predefined dose groups of palbociclib
Description: hydroxychloroquine group of 600mg bid combined with three predefined dose groups of palbociclib: 100mg QD, 150mg QD, and 200mg QD, separately.
Study NCT05953350 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RP2D dose of 600mg bid of hydroxychloroquine combined with palbociclib was selected for phase II clinical trial.
Description: After the exploration of 600mg bid dose of hydroxychloroquine combined with palbociclib, and the maximal tolerated dose (MTD) was determined, then RP2D dose of 600mg bid dose of hydroxychloroquine combined with palbociclib was selected for phase II clinical trial.
Study NCT06047808 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Storytelling Through Music
Description: Storytelling Through Music is a six-week expressive arts intervention.
Study NCT04961294 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electro-Acupuncture
Description: Acupuncture used for thousands years is part of traditional Chinese medicine. We use electro-acupuncture to treat our patients because it is more sufficient than traditional acupuncture and proved effectively treating protracted withdrawal syndrome of opioid use disorder. Paired alligator clips of the EA apparatus will be attached to the needle holders of Shenmen and Neiguan points on both sides. EA stimulation will last for 30 min with a continuous wave of 2/100Hz and intensity of 10-15 mA which patients can stand. All needles will be removed in 30 min and use a dry sterilised cotton ball to press the points in case of bleeding.
Study NCT04380844 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Beprevent
Description: 10 will become part of the intervention group. At first, they are given a series of questionnaires, later (1 day later) we stay at their home to install the Beprevent device, which will remain in their home for a period of two weeks, to finish and once the device of your home, we will proceed to pass the same questionnaires as at the beginning of the test, in order to compare results.
Study NCT05611580 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chronic Disease Risk Reduction
Description: The intervention involves education information about chronic diseases and way to reduce risk for developing chronic diseases and/or decrease worsening of existing conditions.
Study NCT04742855 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: Probiotics
Description: Study product is packaged as powders in a sachet. Participants and their parents will be instructed to dissolve the powder in water or milk, and to drink it in the morning and/or evening.
Study NCT06565182 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The intervention consists of two different types of moderate intensity exercise: Continuous aerobic and resistance exercise.
Study NCT04827459 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Coach App
Description: Participants will be encouraged to interact with the mobile app daily for as much time as they wish, or for as little as 5 - 10 minutes, over a 7-week period.
Study NCT05714033 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ventilatory Strategy To Prevent Atelectasis
Description: Given
Study NCT05714033 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lateral Decubitus Strategy (LADS)
Description: Given
Study NCT04863885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Participants will receive Ipilimumab 3 mg/kg
Study NCT04863885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Participants will receive Nivoumab 1mg/kg
Study NCT05363410 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MagnéVie B6®
Description: micronutrient supplement
Study NCT05363410 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo supplement
Study NCT06196034 — intervention group
Intervention type: GENETIC
Intervention: No intervention
Description: No intervention
Study NCT06407232 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letermovir
Description: 480 mg taken orally once daily, for 84 days
Study NCT06309186 — intervention group
Intervention type: OTHER
Intervention: Evaluation of midwifes' burnout
Description: Burnout evaluated by questionnaires
Study NCT06452589 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FieldForce Ablation System
Description: The FieldForce Ablation System is indicated for cardiac electrophysiologic mapping, delivery of diagnostic pacing stimuli, and pulse field ablation of cardiac tissue. When used with the FieldForce Ablation Catheter, the FieldForce System is intended to be used in the right/left atria and/or left/right ventricle to deliver PFA ablation lesions in the selected areas of the chamber.
Study NCT05770245 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The novel electrolyzed water spray
Description: The researcher used electrolyzed water or piped water to treat the diseased area two times a day for five days. The trial consists of 7 study visits (day 1-day 7). The reduction in the disease area of discomfort or itching scores and promoting healing of the damaged skin of patients with mild dermatophytosis event assessments will be performed at each visit. Safety analysis will be assessed based on the reports of adverse events during the study.
Study NCT05284084 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bed Head elevation, H2 blockers and mouth wash
Description: Elevation of the bed head to 15, 30 and 45 degrees, daily H2 blockers administration and mouth wash BID.
Study NCT05284084 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Data collection for comparison
Description: Data collection for comparison
Study NCT05284084 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Data collection for comparison
Description: Data collection for comparison
Study NCT04846842 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gimatecan
Description: Patients will receive gimatecan orally at the fixed dose level on day 1-5 every 4 weeks.
Study NCT05531604 — intervention group
Intervention type: BEHAVIORAL
Intervention: appetitive conditioning
Description: The investigators will examine acquisition and extinction of learned associations to positively-valenced, socially rewarding yet symptom-neutral infant laughter sounds in an appetitive conditioning paradigm. The investigators will also examine spontaneous recovery of this association 24 hours later when re-presented with these cues, and the reinstatement of this association when re-exposed to infant laughter.
Study NCT05607433 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cook ®Airway Exchanger Catheter
Description: A tube exchanger is a small calibre , flexible tube used to guide endotracheal intubation through a supraglottic device.
Study NCT06535802 — intervention group
Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study NCT06535464 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Hypotension Prediction Index
Description: Fluid management guided by Hypotension Prediction Index
Study NCT06535464 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: No Hypotension Prediction Index
Description: Fluid management not guided by Hypotension Prediction Index
Study NCT05942976 — intervention group
Intervention type: OTHER
Intervention: ULTRASOUND
Description: 10 enthesis areas will be evaluated in 20 minutes with ultrasound.
Study NCT05290493 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NB-001
Description: NB-001 is a non-stimulant activator of multiple metabotropic glutamate receptors (mGluRs).
Study NCT05290493 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching, inactive placebo
Study NCT05907655 — intervention group
Intervention type: DRUG
Intervention: Nitroglycerin 0.3 MG
Description: Sublingual nitroglycerin will be used to provoke spontaneous-like migraine attacks in migraine patients. A dose of 0.9 mg of sublingual nitroglycerin will be used. The same dose will be administrated to controls.
Study NCT05907655 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI
Description: The following brain MRI sequences will be acquired before and after nitroglycerin administration: fluid attenuated inversion recovery (FLAIR), 3D T1-weighted inversion recovery prepared gradient echo, diffusion weighted sequence and 3D susceptibility weighted images.
Study NCT05907655 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sampling
Description: Plasma levels of neuropeptides involed in migraine will be measured using commercially available enzyme-linked immune-sorbent assay (ELISA) kits. All ELISA will be performed by the same experienced technician who will be blinded for the clinical diagnosis.
Study NCT05907655 — intervention group
Intervention type: DEVICE
Intervention: Sleep profiler
Description: Sleep architecture will be investigated using the Sleep Profiler. Sleep Profiler is medical device with CE mark which is produced by Advanced Brain Monitoring and distributed throughout Italy exclusively by Medigas. Sleep staging will be automatically performed for 30-second epochs throughout a dedicated software and a standardized and validated procedure. Frontopolar EEG signal waveforms will be visually inspected to confirm the accuracy of the auto-staging.
Study NCT04344873 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo injection at day one and day fourteen.
Study NCT05122663 — intervention group
Intervention type: BEHAVIORAL
Intervention: Vestibular Rehabilitation
Description: Vestibular Rehabilitation refers to the specific interventions that physical therapists provide to patients with dizziness and vertigo symptoms. These interventions can involve repositioning maneuvers, habituation exercises, gaze stabilization, and/or balance training exercises, depending on the specific etiology of dizziness and vertigo per an established clinical protocol utilizing a patient's history and exam findings. Physical therapists instruct patients in how to perform these exercises at home and provide instructions and referral for patients to follow-up with an outpatient physical therapist for further care.
Study NCT05122663 — intervention group
Intervention type: OTHER
Intervention: Usual Care
Description: Usual Care refers to any combination of diagnostic testing, medications, and patient education or counseling provided by a patient's treating ED physician.
Study NCT04344873 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abatacept 10 mg/kg
Description: Abatacept injection at day twenty eight and day forty two.
Study NCT05168293 — intervention group
Intervention type: OTHER
Intervention: Detection of HBV-DNA in Peripheral Blood Mononuclear cells
Description: Detection of HBV-DNA level in Peripheral Blood mononuclear cells
Study NCT06422481 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fluid administration
Description: Patients will receive fluid administration (500 mL of saline over 30 minutes). The indication of fluid administration will be left to the discretion of the attending physician.
Study NCT06422481 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Norepinephrine administration or increase in norepinephrine dosage
Description: Patients will receive norepinephrine or norepinephrine dosage will be increased if necessary to achieve the appropriate mean arterial pressure level. The indication of norepinephrine administration or increase in norepinephrine dosage will be left to the discretion of the attending physician.