AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05107687 — intervention group
Intervention type: BEHAVIORAL
Intervention: Smoking cessation
Description: Assisted Smoking Cessation- Subject is provided professional support provided by tobacco cessation specialist.~Unassisted Smoking Cessation- Subject provided resources and attempts to quit smoking without professional support.~The subject selects their preferred intervention.
Study NCT05445869 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ProSomnus® EVO Sleep and Snore Device
Description: The ProSomnus® EVO Sleep and Snore Device is an intraoral device for snoring and obstructive sleep apnea. It works by repositioning the mandible during sleep, thereby improving the flow of air through the patient's pharyngeal space. The ProSomnus® EVO Sleep consists of maxillary and mandibular device arches that are CAD/CAM designed with twin-mated posts and digitally milled to be patient-specific according to physician prescription. Prescribed advancements can be achieved by simply removing the current upper or lower device arch and inserting the next upper or lower device arch in the mandibular advancement series. The device does not have any adjustment mechanisms to modify or maintain the mandibular position such as pistons, screws, straps, or repositioning elastics. The device is supplied nonsterile.
Study NCT05119998 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI325 + sintilimab
Description: IBI325 + sintilimab combination does-escalation Patients will receive IBI325 and sintilimab until progressive disease, intolerability, or other reasons leading to treatment discontinuation
Study NCT05119998 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IBI325
Description: IBI325 monotherapy does-escalation Patients will receive IBI325 until progressive disease, intolerability, or other reasons leading to treatment discontinuation
Study NCT05280223 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: injection of 1 microgram/kg dexmeditomidine + 10 cc saline injection nearby median nerve as hydrodissection
Study NCT05280223 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyalase
Description: injection of Hyalase + 10 cc saline injection nearby median nerve as hydro-dissection
Study NCT06353620 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Rey Complex Figure Test
Description: Memeory functioning evaluation
Study NCT00633230 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standardized herbal formula, Sho-saiko-to (SST)
Description: 3 capsules containing 700 mg of the Sho-saiko-to (SST) herbal extract/capsule and 28 mg of the excipients, magnesium stearate, and silicon dioxide/capsule 2 x day
Study NCT00633230 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo capsule identical to the active herbal formula
Description: 3 placebo capsules 2 x day
Study NCT06000631 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Ride-On Car Training in a standing posture with a 2-hour session
Description: A licensed, independent therapist and caregivers will provide the training program in the public space in the university for a total of 12-week intervention based on ecological and dynamic systems theories. Training will concentrate on building the concept of casual effect on the control system and car motion, practicing goal-oriented driving (e.g., driving 200 meters and reach for a toy or contact with a person, play hide-and-seek) in certain public spaces, including hallways, convenient stores, garden, museum and upper limb use in functional tasks with driving, facilitating hand use in functional tasks for exploration and applying various motor skills for mobility and socialization in natural play session. Every week's treatment program will preplanned and adjusted by the therapist and the caregivers through discussion and clinical observation of participant's performance in the previous session. Participants will continue their regular therapy during the whole study.
Study NCT06000631 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Ride-On Car Training in a standing posture with a 1-hour session
Description: A licensed, independent therapist and caregivers will provide the training program in the public space in the university for a total of 24-week intervention based on ecological and dynamic systems theories. Training will concentrate on building the concept of casual effect on the control system and car motion, practicing goal-oriented driving (e.g., driving 200 meters and reach for a toy or contact with a person, play hide-and-seek) in certain public spaces, including hallways, convenient stores, garden, museum and upper limb use in functional tasks with driving, facilitating hand use in functional tasks for exploration and applying various motor skills for mobility and socialization in natural play session. Every week's treatment program will preplanned and adjusted by the therapist and the caregivers through discussion and clinical observation of the participant's performance in the previous session. Participants will continue their regular therapy during the whole study.
Study NCT06000631 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Therapy with a 1-hour session
Description: The other independent OT will be responsible for providing conventional therapy in the same location as the ROC-Stand training for a total of 24-week intervention based on the developmental and motor learning theories. The goals are to improve certain motor skills or psychosocial skills based on each participant's current developmental stage. The general purpose of the training is to facilitate the developmental scales and improve mobility, socialization, and upper limb use in functional tasks.
Study NCT05886530 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: Observational data collection only.
Study NCT05359133 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tetrodotoxin
Description: TTX for Injection, 30 µg/mL, is a sterile, nonpyrogenic, white, lyophilized powder provided in a 5 mL glass single-use vial with a rubber stopper and aluminum overseal. Upon reconstitution of the lyophilized product with 1.1 mL of sterile water for injection, each vial delivers 1 mL of fluid containing 30 µg of TTX with a pH of 4.0 to 5.5
Study NCT05359133 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for injection is a sterile 0.9% sodium chloride injection or normal saline for injection. To ensure blinding, subjects receiving placebo will receive the same volume (1.0 mL) for injection to match the volume used for the cohorts assigned to receive active trial drug.~Route and frequency: 1.0 mL of placebo, SC injection in the thigh or abdomen, twice daily for 4 Days in each treatment Cycle.
Study NCT04626089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: metformin glycinate
Description: Participants randomized to metformin glycinate wil take 620 mg bid (PO) plus standard treatment for 14 days
Study NCT04626089 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: Participants randomized to placebo will take a tablet bid (PO) plus standard treatment for 14 days
Study NCT05407051 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Centered Treatment
Description: In the Family-Centered Treatment Arm, parents would be given the same list of mental health referrals and crisis numbers, but in this condition, they would authorize researchers to share their contact information with the partner agency, Catholic Charities, and would then be linked directly to bilingual adult mental health services there with a behavioral health provider who would provide collateral therapy to parents via telehealth. Although parents will be referred to the community partner for therapy as a part of the research intervention, the behavioral health providers at the community partner will be providing therapy as they usually do for these participants in line with their usual job duties.
Study NCT05407051 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: All participants (parents) would receive follow-up calls from a MetroHealth research personnel at 3 months and 6 months to measure changes in parent mental health outcomes, as well as satisfaction.~Children of parents in both conditions will receive treatment as usual which includes brief consultation for 3-5 sessions with an integrated MetroHealth behavioral health provider which is already standard practice in the clinic. Sessions typically occur monthly. Teens will be re-administered the Patient Health Questionnaire -9 by the integrated behavioral health provider as a part of clinical practice to measure treatment progress and this information will be obtained at the end of 6 months of treatment via chart review (see data sheet). Repeated measurement of patient's symptoms over the course of several months of treatment is common in clinical practice to measure patient's symptom improvement.
Study NCT06323798 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI
Description: Standard paranasal sinus MRI
Study NCT04846660 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Production pressure
Description: Participant exposed to production pressure
Study NCT04734821 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near Infra-Red Fluorescence Guided Surgery
Description: ICG injection around tumor each four direction by endoscopy followed by NIR fluorescence guidance laparoscopic or robotic esophagectomy or gastrectomy
Study NCT05129514 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Lymphatic Drainage (MLD)
Description: The participant will be placed in a supine position and manual lymphatic drainage will be performed for 50 minutes. During the three intervening days, daily 50 minute sessions of manual lymphatic drainage will be provided.
Study NCT06018259 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: healthy volunteers blood sampling
Description: One blood sample will be taken from healthy volunteers in order to isolate PBMC and to assess the effect of the lipid of interest on them PBMC will be activated in vitro (e.g. using LPS or PHA) in the presence or absence of the lipid of interest.
Study NCT06027411 — intervention group
Intervention type: DEVICE
Intervention: qER (qER EU 2.0)
Description: Qure.ai's emergency room software solution qER (qER EU 2.0) is an AI medical device, developed by training a deep-learning algorithm using over 300,000 scans labelled by expert radiologists. qER has been shown to be accurate in identifying a range of abnormalities in NCCT head scans as well as prioritising them for urgent review and radiologist reporting. It is designated as a clinical support tool and, when used with original scans, can assist the clinician to improve efficiency, accuracy, and turnaround time in reading head CTs.
Study NCT04713618 — intervention group
Intervention type: PROCEDURE
Intervention: Pelvic Examination
Description: Undergo pelvic exam
Study NCT04713618 — intervention group
Intervention type: OTHER
Intervention: Survey
Description: Complete surveys
Study NCT06434129 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: DTI
Description: Diffusion MRI imaging
Study NCT04619212 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: breast pumping as per SoC but on new software for the pump
Description: breast pumping as per SoC but on new software for the pump
Study NCT05063032 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrecuency ablation
Description: Radiofrequency ablation to treat left atrial flutter, guided by high-density mapping versus linear ablation.
Study NCT05063032 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Radiofrecuency ablation
Description: Radiofrequency ablation to treat left atrial flutter, guided by high-density mapping versus linear ablation.
Study NCT02193217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-1303-Low
Study NCT02193217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MT-1303-High
Study NCT02193217 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fingolimod
Study NCT05886608 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: AI 500™ SINGLE-DOSE GEL
Description: AI500™ SINGLE-DOSE GEL is a hydrogel to be applied to intact skin, intended to provide relief in cases of pain due to tension in muscles and adjacent tissues, to improve movement and function.
Study NCT02193217 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT05083065 — intervention group
Intervention type: BIOLOGICAL
Intervention: Covid-19 vaccine
Description: * First dose or complete cycle of Comirnaty (Pfizer/BioNTech) vaccine~* First dose or complete cycle of Spikevax (Moderna) vaccine~* First dose or complete cycle of AstraZeneca/Vaxzevria vaccine~* Complete cycle of vaccination using one type of vaccine for the first dose and a different type for the second dose~* Janssen (Johnson \& Johnson) vaccine (single dose)
Study NCT05088811 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: WRAP53, UCA-1
Description: Diagnostic value of UCA-1 and WRAP53 in HCC
Study NCT05295719 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Omega-3 polyunsaturated fatty acid
Description: 4 grams n-3 PUFA (AlaskOmega®) per day (3000 mg EPA and 1000 mg DHA)
Study NCT05295719 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega-3 polyunsaturated fatty acid
Description: 4 grams n-3 PUFA (AlaskOmega®) per day (3000 mg EPA and 1000 mg DHA)
Study NCT05295719 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: High-Intensity Interval Training
Description: A 4 x 4 high-intensity interval training (HIIT) exercise program 3 days/week for 6 weeks. This will include a 3 min warm up at 15% watt max followed by 4 intervals for 4 min at 65% watt max with 3 min active recovery at 15% watt max.
Study NCT05295719 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-Intensity Interval Training
Description: A 4 x 4 high-intensity interval training (HIIT) exercise program 3 days/week for 6 weeks. This will include a 3 min warm up at 15% watt max followed by 4 intervals for 4 min at 65% watt max with 3 min active recovery at 15% watt max.
Study NCT05295719 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Safflower oil
Description: 4 grams safflower oil (AlaskOmega®) per day
Study NCT05295719 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Safflower oil
Description: 4 grams safflower oil (AlaskOmega®) per day
Study NCT05295719 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Flexibility training
Description: 30 min of stretching 3 days/week for 6 weeks
Study NCT05295719 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Flexibility training
Description: 30 min of stretching 3 days/week for 6 weeks
Study NCT05824936 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pilot study arm for technology-enhanced asthma intervention
Description: Participants will be enrolled in a remote monitoring program using monthly remote study visits which will include the use of a mobile spirometer (device for testing lung function). Participants will complete monthly remote study visits visits using telehealth platform and will complete lung function testing during the visit using a mobile spirometer as well as remote study measures.
Study NCT05451355 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Safety Check-In
Description: Prototype decision aid to support within-family communication and decision making about firearm storage.
Study NCT05451355 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: AAP Firearm Storage Web Page
Description: Educational web page that discusses safe firearm storage practices.
Study NCT05598723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IncobotulinumtoxinA (XEOMIN®)
Description: IncobotulinumtoxinA (XEOMIN®) is injected into specific targets at two different time points. Changes in chronic migraine frequency and duration are recorded and compared.
Study NCT05598723 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: OnabotulinumtoxinA (BOTOX®)
Description: OnabotulinumtoxinA (BOTOX®) is injected into specific targets at two different time points. Changes in chronic migraine frequency and duration are recorded and compared.
Study NCT05463068 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVX-Cov2373
Description: Intramuscular (deltoid) injection of SARS-CoV-2 rS co-formulated with Matrix-M adjuvant (0.5 mL) on Day 1
Study NCT05140551 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: COMPASS: digital CBT
Description: COMPASS is an evidence based digital CBT intervention with guided therapist support, tailored to treat anxiety and/or depression in long term conditions (LTCs). The intervention consists of eleven modules/sessions in which CBT techniques are taught. Users of COMPASS receive guided therapist support from a trained therapist. The guided support aims to help patients identify and apply the CBT skills outlined in COMPASS to meet their individual needs and experiences of living with LTC(s). The support can occur through in-site messaging or via the telephone.
Study NCT05731206 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hydrolyzed protein infant formula
Description: Hydrolyzed protein infant formula
Study NCT05731206 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: commercially available hypoallergenic infant formula
Description: commercially available hypoallergenic infant formula
Study NCT06551870 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: The complexity of the games will increase as the levels of the sports games advance, which leads to faster movements with greater demands to progress in the sequence of the games, which allows reaching increases in intensity.
Study NCT04353895 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Guidance for pedicle screw insertion (Mazor Stealth)
Description: Using imaging devices and navigation for guidance, we perform a posterior vertebral fusion with pedicle screw insertion
Study NCT04353895 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Guidance for pedicle screw insertion (O-arm Navigation)
Description: Using imaging devices and navigation for guidance, we perform a posterior vertebral fusion with pedicle screw insertion
Study NCT06435910 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DC vaccines
Description: Antigen-presenting and immune modifying DCvacs to treat MM
Study NCT04775615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DDO-3055 tablets；Placebo
Description: Low dose：DDO-3055 tablets for 7 days or Placebo for 7 days
Study NCT04775615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DDO-3055 tablets；Placebo
Description: Medium dose：DDO-3055 tablets for 7 days or Placebo for 7 days
Study NCT04775615 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DDO-3055 tablets；Placebo
Description: High dose：DDO-3055 tablets for 7 days or Placebo for 7 days
Study NCT04751981 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient Specific Guide
Description: For lumbar fusion pedicle screws will be placed with the aid of patient specific guides.
Study NCT04751981 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Navigation
Description: Conventional navigation will be used to place pedicle screws.
Study NCT06435481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3D printed chewable formulation of hydrocortisone
Description: Administration of a novel hydrocortisone formulation provided as chewable tablets. Each tablet, manufactured with a volume dosing device (3D printer), contains a precise dosage of hydrocortisone.
Study NCT06435481 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral suspension of hydrocortisone
Description: Administration of a standard hydrocortisone oral suspension. The solution, based on simple syrup, contains 1mg of hydrocortisone per milliliter.
Study NCT05361356 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Spectral CT scanning
Description: Volunteer accept spectral CT scanning
Study NCT05832736 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Robotic hemi-prostatectomy with urethral preservation
Description: Robotic hemi-prostatectomy with urethral preservation
Study NCT05528809 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: A blood sampling will be performed during the inclusion visit (day 0).
Study NCT05528809 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood sampling
Description: A blood sampling will be performed during the inclusion visit (day 0).
Study NCT06372405 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive reappraisal
Description: Cognitive reappraisal is a psychotherapeutic strategy utilized to regulate emotions by reinterpreting the meaning of stimuli. Participants will receive instructions on generating and implementing cognitive reappraisal (distancing and reframing) in both misophonic and non-misophonic contexts and will be practicing it within psychotherapeutic sessions. The program consists of four weekly online psychotherapeutic sessions: the first session will be a 90-minute group session, followed by three individual sessions, each lasting 30 minutes.
Study NCT06372405 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Schultz Autogenic Training
Description: Schultz Autogenic Training is a relaxation technique aimed at promoting relaxation and reducing physiological arousal. It consists of six exercises focusing on sensations of heaviness, warmth, heartbeat, breathing, abdominal warmth, and coolness of the forehead. The program consists of four weekly online psychotherapeutic sessions: the first session will be a 90-minute group session, followed by three individual sessions, each lasting 30 minutes.