AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04789759 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Socket Preservation - Bond Apatite synthetic bone substitute
Description: Pre-op CBCT scanner for evaluating bone conditions around hopeless tooth. If 1/3 of the buccal plate is missing, considered a class 2 alveolar socket.~Extraction of tooth and place 2/3 biphasic calcium sulfate cement matrix's with Hydroxyapatite (HA granules) , condensed , and covered with a resorbable membrane suture to the adjacent tissue.~At implant placement ,take bone for histological preparation and histomorphometric analysis of the healing pattern.~At T0, T1 and T2 measure adjacent teeth periodontal status , Probing Depth , bleeding on probing.~Volumetric measurements, will use fixed landmarks (ex. adjacent teeth) to calibrate the STL measurements. Calculate the difference between pre-extraction socket and the post treatment with the alloplastic material.~Primary and secondary stability will be measured by ISQ units with a RFA machine, that will include the machine to measure and the magnetic tip to be screwed in the implant platform.
Study NCT04789759 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Socket healing - No Filler
Description: Pre-op CBCT scanner for evaluating bone conditions around hopeless tooth, at extraction day, no flap opening , atraumatic extraction, no biomaterial filler, At T0, T2 measure adjacent teeth periodontal status , Probing Depth , bleeding on probing.~Volumetric measurements will include an intramural scanner from all the stages , we will use fixed landmarks (ex. adjacent teeth) to calibrate the STL measurements. Calculate the difference between pre-extraction socket and the post treatment with the alloplastic material.
Study NCT06250868 — intervention group
Intervention type: DEVICE
Intervention: Kerato-Refracto Tonometer
Description: measures pressure inside the eye and thickness of the cornea.
Study NCT05494866 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cobicistat Oral Tablet
Description: Cobicistat Oral Tablet
Study NCT05494866 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabin
Description: Gemcitabin
Study NCT05494866 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: nab-Paclitaxel
Study NCT05559645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DZD9008
Description: Daily dosing of DZD9008 200mg
Study NCT05559645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DZD9008
Description: Daily dosing of DZD9008 300mg
Study NCT05085418 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Assigned Interventions CD19/BCMA CAR T-cells
Description: Drug: CD19/BCMA CAR T-cells Each subject receive CD19/BCMA CAR T-cells by intravenous infusion Other Name: CD19/BCMA CAR T-cells injection
Study NCT06031818 — intervention group
Intervention type: OTHER
Intervention: The explanation of deep learning framework (VAE-MLP) , including counterfactual explanations and layerwise relevance propagation
Description: The radiologist and clinicians will be provided the model prediction results with the explanation of the model and they will fill in a questionnaire to evaluate the usability of the interpretable framework.
Study NCT06031818 — intervention group
Intervention type: OTHER
Intervention: The model prediction
Description: The radiologist and clinicians will be provided the model prediction results without the explanation of the model and they will be asked to give their own prediction.
Study NCT06031818 — intervention group
Intervention type: OTHER
Intervention: The model prediction and the explanation of deep learning framework (VAE-MLP) , including counterfactual explanations and layerwise relevance propagation
Description: The radiologist and clinicians will be provided the model prediction results with the explanation of the model and they will be asked to give their own prediction.
Study NCT05886972 — intervention group
Intervention type: BEHAVIORAL
Intervention: Awareness about propofol injection induced pain
Description: The aim of the study is to observe the effect of patient awareness about the possibility of occurrence of pain during propofol injection on the rate of incidence and severity of pain during injection as a primary goal as the pain score of propofol injection pain is the main end point of the study .
Study NCT05413200 — intervention group
Intervention type: DRUG
Intervention: Isotretinoin
Description: oral isotretinoin with a standard dose regime for 90 days
Study NCT04996225 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobics exercises, Balance exercises
Description: Aerobic exercise, or endurance exercise, is a subdivision of physical exercise that improves cardiovascular and respiratory health. Additionally, it is generally assumed to increase well-being and reduce negative mood states such as anxiety and depression.
Study NCT04996225 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Aerobics exercises, Balance exercises
Description: Aerobic exercise, or endurance exercise, is a subdivision of physical exercise that improves cardiovascular and respiratory health. Additionally, it is generally assumed to increase well-being and reduce negative mood states such as anxiety and depression.
Study NCT05686499 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Didactic Lectures and demonstrations
Description: 1. Trainees will receive 4-6 hours of didactic colonscopy lecture sessions based on the American Board of Surgery Flexible Endoscopy curriculum for general surgery residents, general surgery resident curriculum (SCORE) endoscopy module, and the Joint Advisory group on GI Endoscopy program adapted to Nigeria context.~2. Trainees will have the opportunity to practice colonoscopy on HF or LF simulators (depending on the arm) with immediate feedback from instructors.
Study NCT05686499 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Didactic Lectures and demonstrations
Description: 1. Trainees will receive 4-6 hours of didactic colonscopy lecture sessions based on the American Board of Surgery Flexible Endoscopy curriculum for general surgery residents, general surgery resident curriculum (SCORE) endoscopy module, and the Joint Advisory group on GI Endoscopy program adapted to Nigeria context.~2. Trainees will have the opportunity to practice colonoscopy on HF or LF simulators (depending on the arm) with immediate feedback from instructors.
Study NCT05659394 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard Wound Care Alone
Description: gold standard compression therapy
Study NCT05659394 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Stand Wound Care plus IPC
Description: gold standard compression therapy plus IPC (WoundExpress)
Study NCT04973306 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Neoadjuvant Chemoradiotherapy
Description: Chemotherapy: carboplatin (AUC 2 mg/mL per min) and paclitaxel (50 mg/m2 of body-surface area) were administered intravenously for five cycles, starting on days 1, 8, 15, 22, and 29. For each cycle, Carboplatin and paclitaxel were administered 30 minutes apart.~Radiotherapy: A total radiation dose of 41.4 Gy was given in 23 fractions of 1.8 Gy, 5 days per week (Radiotherapy was performed on the 2nd, 3rd, 4th, 5th, and 6th day in each cycle, and only 3 times in the 5th cycle)
Study NCT04973306 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neoadjuvant Chemoradiotherapy
Description: Chemotherapy: carboplatin (AUC 2 mg/mL per min) and paclitaxel (50 mg/m2 of body-surface area) were administered intravenously for five cycles, starting on days 1, 8, 15, 22, and 29. For each cycle, Carboplatin and paclitaxel were administered 30 minutes apart.~Radiotherapy: A total radiation dose of 41.4 Gy was given in 23 fractions of 1.8 Gy, 5 days per week (Radiotherapy was performed on the 2nd, 3rd, 4th, 5th, and 6th day in each cycle, and only 3 times in the 5th cycle)
Study NCT04973306 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Tislelizumab (200mg/time) was administered intravenously on the 1st and 22nd day.~The intravenous injection lasts about 30 minutes (micropump is recommended, intravenous bolus is prohibited, duration should be not less than 20 minutes and not more than 60 minutes);
Study NCT04973306 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended)
Description: After neoadjuvant therapy, patients in groups receive Ivor-Lewis or Mckeown Esophagectomy (Mckeown Esophagectomy recommended)
Study NCT04973306 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended)
Description: After neoadjuvant therapy, patients in groups receive Ivor-Lewis or Mckeown Esophagectomy (Mckeown Esophagectomy recommended)
Study NCT04814433 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride with Epinephrine
Description: Topical lidocaine product is FDA approved as an amide local anesthetic in any indication for relief of pain associated with superficial minor surgery and as an adjunct for local infiltration anesthesia. It is frequently used as a standard local anesthetic for surgical procedures.~Each mL contains lidocaine hydrochloride and epinephrine, with 0.5 mg sodium metabisulfite as an antioxidant and 0.2 mg citric acid as a stabilizer.~Total of 5 mLs per open surgical study arm involving lidocaine hydrochloride and epinephrine will be given
Study NCT04814433 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine Hydrochloride with Epinephrine
Description: Topical bupivacaine is FDA approved as indicated for the production of local anesthesia for procedures by infiltration injection. It is frequently used as a standard local anesthetic for surgical procedures.~Each mL contains bupivacaine hydrochloride and 0.005 mg epinephrine, with 0.5 mg sodium metabisulfite as an antioxidant and 0.2 mg citric acid (anhydrous) as stabilizer.~Total of 5 mLs per open surgical study arm involving Bupivacaine Hydrochloride with Epinephrine will be given
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab（neoadjuvant）
Description: Tislelizumab 200 mg administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin （neoadjuvant）
Description: Cisplatin 75 mg/m2 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-paclitaxel （neoadjuvant）
Description: Nab-paclitaxel 260mg/m2 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical resection
Description: Standard of care
Study NCT06323369 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical resection
Description: Standard of care
Study NCT05737420 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Video call
Description: The on-call neurologist can see and communicate with the patient via live stream video-call.
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin（adjuvant）
Description: Cisplatin 100 mg/m2 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin（adjuvant）
Description: Cisplatin 100 mg/m2 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab（adjuvant）
Description: Tislelizumab 200 mg administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation
Description: Recommended, standard of care
Study NCT06323369 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiation
Description: Recommended, standard of care
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin（neoadjuvant）
Description: Cisplatin AUC=5 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin（adjuvant）
Description: Cisplatin AUC=5 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06380439 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: wrist ankle acupuncture
Description: wrist ankle acupuncture: wrist ankle acupuncture using 0.25 x 25mm filiform needle on lower 1, lower 4, lower 5 area ipsilateral to the surgical side, then covered with 5cm long micropore, retention for 4 hours
Study NCT06380439 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: wrist ankle acupuncture
Description: wrist ankle acupuncture: wrist ankle acupuncture using 0.25 x 25mm filiform needle on lower 1, lower 4, lower 5 area ipsilateral to the surgical side, then covered with 5cm long micropore, retention for 4 hours
Study NCT06323369 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin（adjuvant）
Description: Cisplatin AUC=5 administered by intravenous (IV) infusion on Day 1 of each 21-day cycle
Study NCT06269068 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Central sensitization inventory
Description: Standardized questionnaire to determine the level of central sensitization. Patients with a score of 40 and above are considered to have central sensitization.
Study NCT06269068 — intervention group
Intervention type: OTHER
Intervention: Short form-36
Description: Standardized questionnaire to investigate the quality of life in patients. The score of the scale is between 0-100. The higher scores are associated with greater deterioration in quality of life.
Study NCT06269068 — intervention group
Intervention type: OTHER
Intervention: Oswestry Low Back Pain Disability Questionnaire
Description: With this scale, it is questioned to what extent the patient is affected by low back pain in selected daily living activities under certain ten headings. In total scoring, disability is expressed as a percentage, and high scores are interpreted in favor of an increase in disability.
Study NCT06269068 — intervention group
Intervention type: OTHER
Intervention: Douleur Neuropathique 4
Description: The questionnaire consists of 10 items; while the nature of pain is questioned in 7 items, the other 3 items include brief sensory examination. Patients with a score of 4 or more out of 10 are considered to have neuropathic pain.
Study NCT06269068 — intervention group
Intervention type: OTHER
Intervention: Visual analogue scale
Description: global pain score on a 0 to 10
Study NCT04338178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Remediation Therapy (CRT)
Description: This intervention consists of mental exercises aimed at improving executive function via practice. Simple cognitive tasks that encourage reflective learning and insight into patient's own thinking process are administered. Exercises target set-shifting (i.e., cognitive flexibility), estimating, organization and planning.
Study NCT04338178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Skills Training (EST)
Description: EST places emphasis on the improvement of inner emotion awareness, facial and body expression recognition and intra- and interpersonal emotion regulation skills. Different modules and interactive exercises are designed to help patients learn about i) the functions and manifestations of emotions, ii) the identification and labelling of own's and others' emotions, iii) tolerating and communicating emotions, and iiii) balancing between negative and positive emotions.
Study NCT04338178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy
Description: CBT intervention aimed to manage food craving by teaching group members cognitive (e.g., restructuring of urge-related thoughts) and behavioural strategies (e.g., increasing awareness through food diaries, relaxation skills, identification of cues that trigger craving, avoidance of high-risk situations for craving, distraction).
Study NCT04338178 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Multidisciplinary outpatient program
Description: Multidisciplinary outpatient program including several consultations with endocrinologists, dietitians, psychologists, nutritionists and/or physical activity coaches. Patients are regularly followed and educated about the importance of lifestyle changes including healthy dietary habits and exercise in weight reduction and maintenance. Patients are also usually given information about nutritional value of various foods and few simple exercises for decreasing and maintaining body weight. This program is therefore planned as part of the usual care and responds to the recommendations of good practice for obesity
Study NCT04968509 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PCSK9 inhibitors and statins with or without ezetimibe
Description: Patients in experimental group are treated with PCSK9 inhibitors (140mg with Evolocumab or 75mg with Alirocumab or 150mg with Tafolecimab subcutaneously every two weeks) and conventional lipid-lowering therapy based on statins (atorvastatin 20-40mg qd with or without ezetimibe 10mg qd, or rosuvastatin 10-20mg qd with or without ezetimibe 10mg qd).
Study NCT04968509 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Statins with or without ezetimibe
Description: Patients in control group are only treated with conventional lipid-lowering therapy based on statins (atorvastatin 20-40mg qd with or without ezetimibe 10mg qd, or rosuvastatin 10-20mg qd with or without ezetimibe 10mg qd).
Study NCT06470386 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alverine
Description: 180 mg/day (1 capsule orally, 3 times a day), taken continuously for 24 weeks
Study NCT06470386 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carvedilol
Description: taken orally, starting dose of 6.25 mg once a day, gradually adjusted according to heart rate to 6.25 mg twice a day, 12.5 mg in the morning and 6.25 mg in the evening, 12.5 mg twice a day, or adjusted to the maximum tolerated dose (heart rate greater than 55 beats/min and systolic blood pressure greater than 90 mmHg), taken continuously for 24 weeks.
Study NCT05350670 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Perineal massage and cold compress
Description: Using perineal massage and cold compress during the second stage of labor to observe the effect
Study NCT06199115 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Photobiomodulation
Description: In oncology, photobiomodulation is used to help heal damaged tissues, improve immune response, reduce inflammation, and prevent or treat certain side effects of treatments such as chemotherapy. Photobiomodulation is also the subject of recent clinical studies to expand its indications (peripheral neuropathies induced by certain chemotherapies.~Patients in the experimental group will receive 3 photobiomodulation sessions per week during their oxaliplatin treatments (6 months), for a total of 72 sessions. Exposition to laser light is 30 minutes for each session.
Study NCT05483985 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hera Score
Description: The device uses patient metadata (patient age, day of image capture) and a software algorithm to analyze features of the blastocyst morphology to provide adjunctive information that may predict further development of the embryo to clinical pregnancy after embryo transfer.
Study NCT05678725 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tACS
Description: used round electrodes（area:3.14cm2） and the montage of a bifrontal setup with C3 as the stimulation electrode, while the return electrode placed on the right shoulder . The dose was at 2mA, 20Hz for 20 minutes.
Study NCT05678725 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tDCS
Description: used round electrodes（area:3.14cm2） and the montage of a bifrontal setup with C3 as stimulation and C4 as return electrodes. The dose was at 2mA for 20 minutes.
Study NCT05678725 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham
Description: used round electrodes（area:3.14cm2） and the montage of a bifrontal setup with C3 as stimulation and C4 as return electrodes. The stimulation lasted for 20 minutes and included a 10-second ramp-up and 10-second ramp-down.
Study NCT06390332 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Giving Information for Trauma Support and Safety (GIFTSS) Training
Description: Training for college health center staff and clinicians on GIFTSS intervention which is a universal education and brief counseling to address sexual violence prevention and intervention.
Study NCT06390332 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Giving Information for Trauma Support and Safety (GIFTSS) Training
Description: Training for college health center staff and clinicians on GIFTSS intervention which is a universal education and brief counseling to address sexual violence prevention and intervention.
Study NCT06390332 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Centering gender Affirming Resources in higher Education (CARE) Learning Modules
Description: Training for college health center clinicians and staff on trans and gender diverse (TGD) affirming clinical practices in addition to sexual violence and alcohol abuse prevention that is inclusive of TGD service users
Study NCT06455527 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active Transcranial Direct Current Stimulation (tDCS)
Description: tDCS will be delivered using the 1x1 Mini CT tDCS device. For active tDCS, the device is programmed to ramp up to 2.0 mA (for 30 seconds), provide constant current throughout the session (29 minutes), and then ramp down (for 30 seconds) at the end. Participants will receive 10 sessions of tDCS over the course of this study on weekdays (M-F).