AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06120049 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [18F]-MFBG PET dosimetry scans
Description: \[18F\]-MFBG will be acquired at the Leuven University hospital on a Siemens Truepoint or GE MI4 PET/CT camera or equivalent newer camera, with low dose CT and 120 MBq injected activity.~Three segments of consecutive whole-body scanning with increasing bed position duration will be carried out up to 3 half-lives (physical half-life T1/2 for 18F = 110 minutes): from 0-90 minutes (scan 1-8), 120-150 (scan 9) and 300-330 (scan 10) minutes post injection. In total 10 whole body biodistribution scans will be taken. Urine will be collected and its total activity measured to measure bladder excretion for correction of integrated bladder organ residence. Before each segment, a low dose whole body CT scan (11 mAs) will be acquired for attenuation correction and organ delineation.
Study NCT06201403 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Determination of biomechanical properties of muscles
Description: All evaluations will be performed with a MyotonPRO (Myoton AS., Tallinn, Estonia) digital palpation device. The data of the cases to be evaluated and the patterns related to the measurements will be transferred to the device by establishing a computer connection. Measurements will be performed unilaterally. The measurement point of the subjects' unilateral muscles will first be marked with a pencil. The physiotherapist will hold the device vertically and apply downward pressure (18N) to the muscle body. When the red light on the plexiglass frame of the device probe turns green, the pressure application will be stopped and will remain constant until 5 strokes are made. In every 5 beats, the duration of 1 beat is 15 ms and the time between beats is 8 ms. The SENIAM sensor location guide will be considered as a reference for the estimated motor point determination in the MyotonPRO measurement.
Study NCT05081154 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product A
Description: P1012915, a nicotine pouch with 8 mg nicotine
Study NCT05698004 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: prone positioning
Description: The target duration of prone positioning is 8 h/d to 10 h/d with 2 to 3 breaks (1-2 hours each), if needed. Daily prone positioning sessions will be protocolized to continue until 1 of the following stopping criteria is met: a relative improvement in the FIO2 requirement by 40% from the baseline value that sustained for 24 hours; endotracheal intubation; or discharge from the ICU.
Study NCT06076239 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ESWT Group
Description: EG were given Extracorporeal Shock Wave Therapy to the trigger point of the patients with a trigger point in one of the supraspinatus, subscapularis and infraspinatus muscles for a total of 5 sessions in 3 weeks (2 sessions in the first week, 2 sessions in the second week, 1 session in the third week) in addition to conventional treatment. 1000 pulses to the trigger point of the patients with a trigger point in one of the supraspinatus, subscapularis and infraspinatus muscles, 500 pulses to the surrounding area, 2 bars, ESWT (GYMNMA Shockmaster 500) was applied for a total of 5 sessions in 3 weeks at 10 Hz, medium energy level (\<0.28 mJ/mm2).
Study NCT06076239 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ESWT Group
Description: EG were given Extracorporeal Shock Wave Therapy to the trigger point of the patients with a trigger point in one of the supraspinatus, subscapularis and infraspinatus muscles for a total of 5 sessions in 3 weeks (2 sessions in the first week, 2 sessions in the second week, 1 session in the third week) in addition to conventional treatment. 1000 pulses to the trigger point of the patients with a trigger point in one of the supraspinatus, subscapularis and infraspinatus muscles, 500 pulses to the surrounding area, 2 bars, ESWT (GYMNMA Shockmaster 500) was applied for a total of 5 sessions in 3 weeks at 10 Hz, medium energy level (\<0.28 mJ/mm2).
Study NCT06076239 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Both EG and CG were given conventional treatment.Conventional treatment is consist of Ultrasound therapy (Gymna Pulson200) (1 mHz. treatment dose average 1.5 w/cm², intermittent with a small head (50%), 5 minutes (45)) around the glenohumeral joint of the cases in both groups participating in the study; TENS applied at an intensity that the patient can tolerate, covering the painful area (modified biphasic asymmetric pulse, and it was set to a pulse width of 100 μs and a frequency of 100 Hz, 20 min,) (Hometech ht 66b); hotpack and exercises (posterior capsule stretching, wand exercises, mobilization approximately 60 minutes of conventional treatment consisting of exercises and shoulder isometric exercises) was applied once a day, 5 times a week in both groups.
Study NCT04935567 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Statistical model for the prediction of VNS efficacy
Description: statistical model for the prediction of VNS efficacy based on a mathematical and statistical analysis of scalp EEG data
Study NCT04935567 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Statistical model for the prediction of VNS efficacy
Description: statistical model for the prediction of VNS efficacy based on a mathematical and statistical analysis of scalp EEG data
Study NCT05081154 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product B
Description: P1013018, a nicotine pouch with 10 mg nicotine
Study NCT05081154 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Product C
Description: P1013015, a nicotine pouch with 8 mg nicotine
Study NCT06409897 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Sequencial increasing of head of the bed elevation and alveolar recruitment maneuver followed by a PEEP titration with 10° of head of the elevation
Description: Patients will be sequentially positioned at 0, 10, 20, 30, and 40 degrees of head-of-bed elevation. An alveolar recruitment maneuver will be performed. For patients with body mass index ≤ 30 kg/m\^2, the maneuver will be conducted in pressure control mode, pressure control = 15 cmH2O, respiratory rate = 20 breaths per minute, and the PEEP will be increased in steps of 5 up to 30 cmH2O. For patients with body mass index > 30, the PEEP will be increased up to 35. Then, a PEEP titration will be performed, tidal volume = 5 mL/Kg, respiratory rate = 25 breaths per minute, and the PEEP will be decreased from 24 down to 4 cmH2O in steps of 2 cmH2O with 30 seconds in each PEEP level. The PEEP titration software of Enlight 2100 will be used to determine the ideal PEEP, defined as the PEEP level with a collapse less than 5%. The alveolar recruitment maneuver will be performed again to reopen the lungs. Then, data will be collected, as with the 0 and 40-degree steps, with ideal PEEP.
Study NCT06098105 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided transversus abdominis plane block
Description: This group will receive ultrasound-guided transversus abdominis plane block by using 1 ml/kg of bupivacaine 0.25% with a maximum volume of 20 mL as a control group.
Study NCT06098105 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic-assisted transversus abdominis plane block
Description: Patients will receive laparoscopic-assisted transversus abdominis plane block by using 1 ml/kg of bupivacaine 0.25% with a maximum volume of 20 mL.
Study NCT06098105 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic-assisted intraperitoneal instillation
Description: This group will receive laparoscopic-assisted intraperitoneal instillation by using 1 ml/kg of bupivacaine 0.25% with a maximum volume of 20 mL will be instilled into the peritoneal cavity immediately after gas insufflation.
Study NCT06098105 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: bupivacaine
Study NCT06098105 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: bupivacaine
Study NCT06443073 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient-reported outcomes for speech disorders: positive
Description: The Communicative Participation Item Bank (CPIB) aims to assess communication participation in all kinds of communication disorders. The Voice Self-Efficacy Questionnaire (VSEQ) monitors self-efficacy in individuals with self-declared voice problems before and after interventions. The Vocal Fatigue Handicap Questionnaire (VFHQ) and the Vocal Fatigue Index (VFI) aim at reflecting vocal fatigue. Both have been adapted to reflect purely positive wording.
Study NCT05902845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RD13-02 cell infusion
Description: CAR-T cells
Study NCT05856084 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Low dose Recombinant Herpes Zoster Vaccine (CHO cells)
Description: 0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with low dose MA105.
Study NCT05856084 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: High dose Recombinant Herpes Zoster Vaccine (CHO cells)
Description: 0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with high dose MA105.
Study NCT05856084 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Positive control
Description: 0.5 mL per dose, containing a total of 50 µg recombinant varicella zoster virus glycoprotein E, adjuvanted with AS01B.
Study NCT05856084 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.5 mL per dose, containing 4.5 mg sodium chloride.
Study NCT06326125 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TICK-B
Description: TICK-B as art-based distraction
Study NCT06326125 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TKTX-Cream
Description: TKTX-Cream as local anesthesia cream
Study NCT06326125 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TICK-B and TKTX-C
Description: TICK-B and TkTx-C as combined intervention approche (pharmacology and non-pharmacology)
Study NCT06519617 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Yi Qi Yang Yin Decoction
Description: The Yi Qi Yang Yin Decoction (Dihuang 15g, Baihe 12g, Nanshashen 15g, celery Qinghao 10g, Malt 10g, Shengma 6g, Chaihu 6g) prescription for patients eligible for qi and yin deficiency was 200 ml twice daily for 12 weeks.
Study NCT06519617 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Hydroxychloroquine Sulfate
Description: Hydroxychloroquine Sulfate Tablets 200-400mg daily for 12 weeks.
Study NCT06504420 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sirolimus
Description: Subjects will receive Sirolimus 1.5mg/d for 48 weeks in addition to their ongoing APS treatment regimen
Study NCT06504420 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will receive Placebo 1.5mg/d for first 24 weeks and Sirolimus 1.5mg/d for next 24 weeks in addition to their ongoing APS treatment regimen
Study NCT03465826 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PainCOACH Pain Coping Skills Training
Description: Migraineurs will participate in 4 weeks of daily headache monitoring, baseline questionnaires, followed by 8 weeks of the PainCOACH migraine mHealth Pain Coping Skills Training program (developed by Drs. Keefe and Rini based on social cognitive theory and in-person pain coping therapy sessions). Following the 8 week mHealth intervention, participants will immediately complete post-treatment assessments and later will complete follow-up assessments at 3 and 6 months.
Study NCT03465826 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as Usual
Description: Participants will keep headache diaries for 4 weeks, followed by baseline assessments + 8 weeks of daily headache monitoring (as a parallel to the PainCOACH intervention). Post-assessments will immediately follow, and participants later will complete follow-up assessments at 3 and 6 months.
Study NCT04914819 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online Behavioral Weight Loss Program
Description: Participants will be enrolled in a 16-week online behavioral weight loss program based on the Diabetes Prevention Program (DPP). The program involves weekly brief videos, a self-monitoring platform, automated feedback, and access to a health coach.
Study NCT04914819 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual weigh-in
Description: Participants will be sent a digital scale and will be asked to complete a virtual weigh-in at home at the start of the study and again after 16 weeks.
Study NCT05047016 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Virtual investigational product
Description: The virtual investigational product is a predefined text (e.g. AB123F). By entering the code into the application, the virtual 'administration' of the IP is conducted.
Study NCT05104749 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Homeopathic Medication
Description: Homeopathic medicines are prepared according to standardized methods as specified by the Homeopathic Pharmacopoeia of the United States (HPUS), which was mandated by Congress to regulate the manufacture of homeopathic medicines as part of the Food, Drug, and Cosmetics Act of 1939. All homeopathic medicines prescribed in this study must be found in the HPUS. For a complete list of homeopathic medicines, contact the researchers.
Study NCT05104749 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inert lactose pellets
Study NCT05936372 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acute intense aerobic exercise
Description: The acute intense aerobic exercise bout (iE) will consist of a 13-minute 20-meter shuttle run. During this exercise bout two speeds, based on a percentage of the estimated maximal oxygen consumption (VO2max), will be combined: a fast-paced speed (fast: 85% of VO2max) and a slow-paced speed (slow: 60% VO2max). A total of 3 series of 3 min of the fast-paced speed will be carried interspersed with 2 series of 2 min of the slow-paced speed. Prior to the iE start, a warm-up protocol consisting of 2 min slow and 1 min fast will be done with the objective to familiarize participants with the iE speeds. A 5-minute rest period will be guaranteed before starting the iE. Transition time between iE and the rotational visuomotor adaptation task (rVMA) will be 4 min.
Study NCT04816786 — intervention group
Intervention type: OTHER
Intervention: no intervention will be administered, this is a retrospective observational study.
Description: no intervention will be administered, this is a retrospective observational study.
Study NCT06044012 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Double layer of buccal myomucosal Flap and buccal pad of fat
Description: The buccal myomucosal flap will be harvested from cheek below stenson papilla and will be sutured over buccal pad of fat which will be sutured at palatal mucosa after complete curettage of infected fistulous tract.
Study NCT05416697 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBD oil
Description: The subjects will receive cannabis 2.7 mg THC 2.5 mg CBD twice daily (1 droplet twice daily; 0.73 mg THC and 0.81 mg CBD/drop, 1.46 mg THC and 1.62 CBD/day) for 1 week then titrate up to 2 droplets twice daily if tolerated (2.92 mg THC and 3.24 CBD per day) and continue the treatment until the end of the study.
Study NCT05416697 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The subjects will receive 1 droplet of placebo twice daily then titrate up to 2 droplets twice daily if tolerated and continue the treatment until the end of the study.
Study NCT06372327 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Daily Exercise Snacks
Description: Participants will be encouraged to break up prolonged sitting at work with brief, high-intensity exercise snacks of varying length / total number depending on condition assignment.
Study NCT04680845 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-affirmation
Description: According to self-affirmation theory (Steele, 1988), defensiveness arises because people are motivated to defend their global sense of self-worth, which in the present case is threatened by perceptions of hearing aids/loss. However, if a person's self-image can be bolstered (affirmed) in a domain that is important to them, thereby preserving self-integrity, the individual should be less likely to process the threatening (i.e., stigmatizing in the present context) information defensively (Steele, 1988).
Study NCT05657392 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: repetitive Transcranial Magnetic Stimulation (rTMS)
Description: Repetitive Transcranial Magnetic Stimulation (rTMS) is a noninvasive intervention that uses magnetic fields to stimulate nerve cells to improve the symptoms of a variety of disorders, including stroke-related motor impairment. Last few decades, it has been revealed that rTMS accelerates motor recovery and may reduce stroke-related symptoms.
Study NCT05657392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 32 electrode electroencephalography (EEG)
Description: 32-electrode EEG will be non-invasively recorded from electrodes placed in a montage over the scalp while the participant is resting
Study NCT06041191 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment
Description: The children included in the study were evaluated in terms of hypermobility and then divided into two groups. Children in both groups were evaluated in terms of sensory processing skills.
Study NCT04921488 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: screening colonoscopy
Description: The screening colonoscopy will be performed by an investigator. The automatic detection and characterization system will be activated at the time of descent of the colonoscopy (after caecal intubation), with video recording (image without CAD EYE and image with CAD EYE). The investigator performing the colonoscopy will be blinded by the results of the CAD EYE.
Study NCT04140474 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Archimedes procedure
Description: All patients will initially have a scanner necessary for planning by the Archimedes system of the tunneling path. each patient will then undergo a general anesthesia as for any bronchoscopy. Then start the Archimedes procedure itself to reach the SPN
Study NCT05431738 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gastroesophageal stent placement
Description: A gastroesophageal stent is placed during a digestive endoscopy performed under general anesthesia, under endoscopic and fluoroscopic control
Study NCT05903378 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Relational touch practice
Description: Relational touch practice during the first bedside session. Touch in care aims to improve the patient's perception of potentially painful or anxiety-provoking acts of care. It is based on techniques of skin contact, developing and deepening.
Study NCT05501457 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Muscle strengthening with neuromuscular electrical stimulation
Description: The effect of peripheral muscle strengthening training in addition to pulmonary rehabilitation in COPD patients on the patient's performance will be examined.
Study NCT06016335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: CT scan
Description: Participants receive a CT scan of the head as part of their regular care. A larger part of the head will be scanned than for standard care.
Study NCT06016335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: MRI scan
Description: Participants receive an MRI scan, specifically for the purpose of the study.
Study NCT06016335 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Synthetic CT scan
Description: Synthetic CT scans will be generated from MRI scans, using the trained machine learning algorithm.
Study NCT05523154 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of bile samples
Study NCT05523154 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of bile samples
Study NCT05523154 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Laboratory Procedure
Description: Undergo routine laboratory testing
Study NCT05523154 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laboratory Procedure
Description: Undergo routine laboratory testing
Study NCT05523154 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nanopore Sequencing
Description: Undergo nanopore sequencing
Study NCT04914221 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JLP-2002
Description: administration of JLP-2002
Study NCT04914221 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Comparator
Description: administration of comparator
Study NCT06367023 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rajyoga Meditation Practice
Description: The intervention will be given for 3 months, For 6 days one hour per day Rajyoga meditation basic course will be provided, followed by 1 hour daily spiritual lesson, Positive thinking and motivation classes will be provided to the intervention group and in control group standard treatment will be given.
Study NCT05603377 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: functional endoscopic evaluation of swallow
Description: functional endoscopic evaluation of swallow
Study NCT06244849 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood samples
Description: A 28 mL (5 EDTA tubes of 4 mL and 2 dry tubes) venous blood will be collected added to the standard blood analysis performed in routine
Study NCT06244849 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Stool simple
Description: A fresh stool sample will be collected and conserved at room temperature until shipment