AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06800144 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Heart rate synchronized music therapy
Description: Participants included in this group will listen to soothing/relaxing music without lyrics in a rhythm synchronized with their heart rate.
Study NCT06800001 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Physical Activity is an 8-week practical intervention for managing the stereotyped behavior \& anxiety. Week 1: Introduction - Build engagement with the help of rapport building. Learn \& practice ball-tapping exercise with warm up \& cool down relaxation exercise. Week 2: Calmness- Practice jumping in trampoline exercise and learn balloon breathing exercise that give calmness. Week 3: Focus enhancement-Learn skills of jumping exercise to increase focus and improve impulse. Week 4: Strength, balance, and stress relief -explore the gym ball exercise in different directions that improves emotional regulation. Week 5: self control - Learn strategies for specific jumping patterns that improves impulse control and focus in children with ASD. Week 6: Reduce Stereotyped Behaviors - Learn complex trampoline exercises. Week 7: Skill Reinforcement- Review exercises, increasing speed or direction changes. Week 8: Integration -Encourage playful interaction to maintain engagement \& consolidate skills.
Study NCT06800001 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Activity
Description: Physical Activity is an 8-week practical intervention for managing the stereotyped behavior \& anxiety. Week 1: Introduction - Build engagement with the help of rapport building. Learn \& practice ball-tapping exercise with warm up \& cool down relaxation exercise. Week 2: Calmness- Practice jumping in trampoline exercise and learn balloon breathing exercise that give calmness. Week 3: Focus enhancement-Learn skills of jumping exercise to increase focus and improve impulse. Week 4: Strength, balance, and stress relief -explore the gym ball exercise in different directions that improves emotional regulation. Week 5: self control - Learn strategies for specific jumping patterns that improves impulse control and focus in children with ASD. Week 6: Reduce Stereotyped Behaviors - Learn complex trampoline exercises. Week 7: Skill Reinforcement- Review exercises, increasing speed or direction changes. Week 8: Integration -Encourage playful interaction to maintain engagement \& consolidate skills.
Study NCT06800040 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory training
Description: Memory training
Study NCT06798376 — intervention group
Intervention type: DRUG
Intervention: ≤4 cycles of neoadjuvant PD-1 Inhibitors combined with chemotherapy
Description: Any PD-1 inhibitors combined with any chemotherapy regimen given before surgery for no more than 4 cycles
Study NCT06798376 — intervention group
Intervention type: DRUG
Intervention: ≥5 cycles of neoadjuvant PD-1 Inhibitors combined with chemotherapy
Description: Any PD-1 inhibitors combined with any chemotherapy regimen given before surgery for no less than 5 cycles
Study NCT06798376 — intervention group
Intervention type: PROCEDURE
Intervention: Gastrectomy
Description: Any type of surgical procedure for gastric adenocarcinoma patients in which part or all of the stomach is removed
Study NCT06454383 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leflunomide
Description: Given PO
Study NCT06454383 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05218460 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MRI examination
Description: All subjects (healthy and pathological subjects) will have an MRI examination with a component of the MRI system under development.
Study NCT05471622 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nudge for PHPC Referral
Description: The case manager and covering providers for inpatients who have been identified according to the study's inclusion criteria as appropriate for Penn Home Palliative Care (PHPC) upon hospital discharge will be asked to refer their patient for these home palliative care services.
Study NCT06799676 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: a combination treatment of Linperlisib and the VRD regimen
Description: Subjects will be administered Linperlisib orally at doses of 40 mg, 60 mg, or 80 mg once daily for 4 consecutive weeks, combined with the VRD regimen at standard doses. Subsequently, during the expansion phase, at least four cycles of Linperlisib at the recommended Phase II dose (RP2D) will be combined with the VRD regimen for induction therapy.
Study NCT06798844 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Spinal Cord Stimulation
Description: SCS is an established treatment for chronic neuropathic pain and the implantation procedure in this study follows the conventional clinical approach. Under local anaesthesia, a lead electrode is positioned in the spinal epidural space at the Th8-Th10 vertebral levels. The electrode is then connected to an external stimulator (implantable pulse generator, IPG), used for the 3-week external trial stimulation. Upon completion of the core trial, the electrode may either be removed or connected to an internal IPG, after extensive counselling and dependent on the FOG outcome and patient's preference. A subsequent long-term open label phase will evaluate the long-term efficacy and safety of SCS on FOG, with a follow-up period of six months. Electrophysiological recordings of the dorsal spinal cord will be conducted at the end of the external trial stimulation and at the 6-month follow-up.
Study NCT06798844 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Spinal electrophysiological recordings
Description: The sole purpose of the control groups in this study, is to facilitate the interpretation of spinal cord electrophysiological characteristics in PD freezers by providing a comparison with individuals without the condition.
Study NCT04452331 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Open Access Audio
Description: Patient obtains secure access to an audio recording of the medical encounter post-visit that is accessible from any internet enabled device.
Study NCT04452331 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: No Access, Patient and Provider Aware of Recording
Description: Patient does not obtain access to audio recording but both patient and provider are aware visit is being recorded.
Study NCT04452331 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: No Access, Provider Unaware of Recording
Description: Patient does not obtain access to audio recording and provider is unaware visit is being recorded.
Study NCT06238895 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tardyferon
Description: Interval Dosing Strategy (Administration of oral iron every second day with double the standard dose instead of every day standard dose)
Study NCT06238895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tardyferon
Description: Interval Dosing Strategy (Administration of oral iron every second day with double the standard dose instead of every day standard dose)
Study NCT06798519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HNC364 Injectable Suspension
Description: Subjects in HNC364 cohort will receive a deep IM injection of HNC364 injectable suspension in the deltoid muscle at a dose of 60 mg every 4 weeks for 4 repeated doses. Subjects will be allowed to leave the clinical site the next day after receiving each dose and return to clinical site on 7 days, 14 days and 28 days (before next administration) after each dose for safety and tolerability assessments. Besides, subjects will return to the clinical site on 4 days after the first dose and the last dose due to PK and PD blood sample collections.
Study NCT06798519 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rasagiline Tablets
Description: Subjects in rasagiline tablets cohort will receive 1 mg of rasagiline tablets orally once daily for 20 days, followed by 2 mg once daily for 5 days. Subjects will remain domiciled at the clinic stay until Day 26 and have a follow-up visit on Day 29 due to PK and PD blood sample collections
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 100mg/10ml/1bottle
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sintilimab
Description: 100mg/10ml/1bottle
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peg-IFNα-2b
Description: 180ug/0.5ml/1bottle
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Peg-IFNα-2b
Description: 180ug/0.5ml/1bottle
Study NCT05178524 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BIFICO
Description: Live combined Bifidobacterium, Lactobacillus and Enterococcus Capsules
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NAs
Description: tablets
Study NCT06357806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NAs
Description: tablets
Study NCT06799936 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CKD Jumpstart- Tips priming intervention
Description: The intervention includes 2 components:~1. Patient Priming: Patients will receive the Jumpstart CKD- Tips communication priming tool within 1 week before and on the day of a target clinic visit, which includes surveys on (i) Understanding of illness and possible treatment options, (ii) Readiness for treatment discussion and information preferences, (iii) Health priorities, goals, and preferences (iv) Preferred roles in decision-making. The Jumpstart CKD- Tips patient priming sheet includes (a) A summary of their survey responses that can be shared with their healthcare team, and (b) Tips on communication with clinician during upcoming visit.~2. Clinician Priming: Within 1 week before and on the day of the target clinic visit, clinicians will receive a Jumpstart CKD- Tips clinician priming sheet which contains (a) An abstracted version of the patients' survey responses and (b) Communication tips tailored to the patient's responses based on Vitaltalk curricula materials.
Study NCT06799442 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: Patients will be placed in lateral position with the surgical site upward. A high-frequency linear ultrasound probe will be placed in a longitudinal parasagittal orientation 2.5-3 cm lateral to the T9 spinous process. The erector spinae muscles will be identified superficial to the tip of the T9 transverse process. An echogenic needle needle will be inserted using an in-plane approach and craniocaudally direction. The tip of the needle will be placed into the fascial plane on the deep aspect of the erector spinae muscle. The location of the needle tip will be confirmed by visible fluid spread lifting the erector spinae muscle off the bony shadow of the transverse process on ultrasonographic imaging.
Study NCT06799442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: 50 mic dexmedetomidine which is diluted to 2ml.
Study NCT06799442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: fentanyl
Description: 100 mic fentanylwhich is also diluted to 2 ml.
Study NCT06798870 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: removable appliances
Description: removable appliances; clear aligner and removable inclined plane, for correcting anterior crossbite vin mixed dentition patient
Study NCT06799299 — intervention group
Intervention type: OTHER
Intervention: No Intervention
Description: No intervention
Study NCT06798584 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: FeoSol Original Iron Supplement Tablets
Description: 325 mg of ferrous sulfate containing 65 mg of elemental iron
Study NCT06798584 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: 21st Century Gelatin Capsules
Description: 600 mg
Study NCT06799923 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: laser electrode
Description: A laser electrode is implanted surgically in the ventral and inteermediary nucleus of the thalamus (VIM).
Study NCT06798090 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Band and Loop Space Maintainer Produced with Three-Dimensional Printer
Description: Band and loop space maintainer produced with three-dimensional printer using micro laser sinterisation method
Study NCT04809051 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stratified Transplant Survival Metric
Description: Both transplant metric conditions display the number of hearts offered to each center, the number of hearts accepted by each center, and the number of transplants performed at each center (in a year), in addition to the condition-specific metrics below. The stratified condition instead features a pair of values corresponding to each center's offers/acceptances/transplant survival rates for donor hearts of optimal or adequate quality.
Study NCT04809051 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SRTR Information Format
Description: The information format varies based on how the transplant hospital statistics are organized when presented to participants on the choice screen. The SRTR conditions mimic the information format present on the SRTR public reporting website.
Study NCT05238454 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SCTV01C
Description: intramuscular injection
Study NCT06798090 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Band and Loop Space Maintainer Produced with Conventional Technique
Description: Band and loop space maintainer produced with conventional methods
Study NCT06798103 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: Erector spinae plane block will be performed using an ultrasound machine with a high frequency linear probe. The patients will be in sitting position to perform the block, the skin is sterilized and the transducer will be placed across the T7 spinous process then move laterally to identify transverse process of T7. Thereafter, the probe will be moved to a parasagittal plane to visualize skin and subcutaneous tissue layers, trapezius muscle, and lastly the erector spinae muscle just superficial to the transverse processes. The in-plane technique will be used, and the tip of the needle will be inserted in the fascial plane deep to the erector spinae muscle. After 2-3 mL of normal saline injection for hydro dissection to verify the correct needle tip placement, 30 mL of 0.25% bupivacaine will be injected deep to the erector spinae muscle. The same technique will be repeated on the contralateral side.
Study NCT05476887 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KP104
Description: KP104 intravenously (IV loading + subcutaneous \[SC\] maintenance every week \[QW\] or every 2 weeks \[Q2W\]) will be administered.
Study NCT05033587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib
Description: Anlotinib a multi-target receptor tyrosine kinase inhibitor.
Study NCT05033587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK105
Description: AK105 is a humanized monoclonal antibody that specifically binds to PD-1.
Study NCT06798103 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic paravertebral block
Description: Thoracic paravertebral block will be performed using an ultrasound machine with a high frequency linear probe. The patients will be in sitting position to perform the block, the skin is sterilized and the transducer will be placed across the T7 spinous process then move laterally to identify transverse process of T7. Thereafter, the probe will be moved 3-5 cm laterally to identify the paravertebral space as the target injection site. After probe being rotated into transverse orientation, the needle will be inserted using the out-plane technique. Once the needle threads the internal intercostal membrane and arrives in the paravertebral space, 3 ml of normal saline will be injected firstly. If displacement sign of the pleura occurs, 25 ml of 0.25% bupivacaine will be then injected into the confirmed paravertebral space. The same technique will be repeated on the contralateral side.
Study NCT06797843 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SPRG-based Resin Composite : (BEAUTIFIL II, Shofu Inc. Kyoto, Japan).
Description: A fluoride releasing, highly aesthetic dental material that is S-PRG (Surface Pre-reacted Glass Ionomer) based , has the ability to recharge fluoride and appropriate for patients with a high caries index.
Study NCT06797843 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alkasite based restoration : Cention N
Description: Cention N offers tooth-coloured esthetics together with high flexural strength. The new filling material belongs to the materials group of Alkasites. The patented alkaline filler increases the release of hydroxide ions to regulate the pH value during acid attacks. As a result, demineralization can be prevented. Moreover, the release of large numbers of fluoride and calcium ions forms a sound basis for the remineralization of dental enamel. The initiator system enables good chemical self-curing.
Study NCT06797843 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: provisional Resin modified glass ionomer followed by Nanohybrid composite
Description: GC Fuji IX GP® EXTRA is the fastest setting glass ionomer on the market.The faster final set saves valuable chair time which provides improved stability against water, an important feature in challenging oral environments. This product contains a next generation glass filler which elicits higher translucency, fluoride release, reactivity and a faster setting time.~Then followed by Conventional Nano hybrid composite restoration(Neo Spectra® ST LV, Dentsply Sirona) which is nano-ceramic, light-cured, radiopaque, universal composite with novel SphereTEC filler technology.
Study NCT06798649 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
Description: This is aimed at assessing whether such feedback can encourage the adoption of healthier lifestyles and enhance adherence to preventive treatments, thereby potentially reducing the incidence of postpartum hypertension and other cardiovascular diseases.~Components of the Intervention:~Vascular Imaging:~Women in the intervention group undergo advanced vascular imaging using ultrasound technology to detect the presence of arterial plaques vs. no information about vascular images in the standard manag group.~The images are analyzed to assess the extent of vascular health, focusing on areas typically affected by cardiovascular risks such as the carotid arteries.~Feedback Delivery:~Detailed results from the vascular imaging are provided to the participants in a comprehensible format by healthcare professionals specialized in cardiovascular health.~This feedback session includes a thorough explanation of the findings, highlighting areas of concern and potential risks.
Study NCT06799949 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ROTEM (TEM Innovations GmbH, Munich, Germany) assay
Description: For each patient, two samples will be collected for ROTEM analysis: one at the beginning of the surgery during the placement of the arterial line (Start ratio) and another at the end during the completion of the surgical wound closure(Final ratio). The arterial line system will be filled with normal saline (0.9% sodium chloride) without the addition of unfractionated heparin. To avoid sample contamination before sampling, a volume of blood equivalent to 5.5-6 times the dead space (calculated from the catheter tip to the three-way stopcock device) will be aspirated. Blood samples for testing will be stored in specialized evacuated coagulation test tubes (Jiangsu Rongye Technology Co., Ltd, Jiangsu, China) and gently mixed with 3.2%-0.109M sodium citrate, for a total volume of 1.8 ml.
Study NCT05238454 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sinopharm inactivated COVID-19 vaccine
Description: intramuscular injection
Study NCT05238454 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty
Description: intramuscular injection
Study NCT05033587 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: The radiotherapy regimen delivered 2.0Gy once a day, five days a week to a total dose of 60Gy.
Study NCT06292936 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance-Based Behavioral Intervention
Description: Intervention will evaluate acceptance-based behavioral treatment (ABT) for individuals who are experiencing weight regain after bariatric surgery. ABT builds acceptance and mindfulness skills that increase the capacity to experience uncomfortable internal states (e.g., food cravings, hunger, negative affect). Online treatments include video modules demonstrating session content as well as interactive features. These interventions are particularly desirable, reduced participant burden, and are cost effective.~ABT provides patients unique skills that directly target causes of dietary non-adherence. ABT provides patients specialized skills to directly target causes of dietary nonadherence (rather that solely repeating behavioral strategies they received during preoperative medical weight management required by their third party payers and bariatric surgery programs).
Study NCT06798675 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nC-001
Description: solid dosage form single dose
Study NCT06798675 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06798337 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physiotherapy group
Description: Participants in the regular physical therapy group performed balance and coordination exercises three times a week without the use of rewards. These subjects completed only physical exercises, without engaging in game-like interactive tasks using virtual reality (VR) glasses. Each session was conducted at the same time for each subject, with a potential variation of ±1 hour.