AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06094920 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Questionnaire: participants' perspectives toward the feasibility of participation in a trial at home with digital technologies
Description: Participant perspectives regarding the feasibility of participating in a home-based trial will be evaluated using a digital questionnaire. This questionnaire includes inquiries adapted from the validated Telehealth Usability Questionnaire, supplemented with additional questions employed in prior studies that assessed the feasibility of decentralized clinical trials. The web application Research Electronic Data Capture 10.0.23 (REDCap - www.projectredcap.org) will facilitate the administration of these digital questionnaires. Participants will receive a link to access the digital questionnaires via email. Weekly telephone calls will be conducted to evaluate adherence to study procedures and monitor the occurrence of adverse events.
Study NCT05397015 — intervention group
Intervention type: OTHER
Intervention: No intervention will be done
Description: No intervention will be done
Study NCT06172439 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: acupressure
Description: Women in the intervention group will receive acupressure for 12 minutes.The acupressure pressure points related to the gynecologic surgery to be performed are named as the large intestine (LI4), stomach (ST36) and spleen (SP6) meridians, respectively. These points are determined by expert opinion and are used for pain control.
Study NCT05489796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl selector
Description: Selector (1 ml; Lock out 10 min): Fentanyl 200 mcg + N/S 16 ml = total 20 ml
Study NCT05489796 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl selector
Description: Selector (1 ml; Lock out 10 min): Fentanyl 200 mcg + N/S 16 ml = total 20 ml
Study NCT05489796 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl continuous
Description: Continuous (2 ml/hr): fentanyl 700 mcg + N/S 86 ml = total 100 ml
Study NCT05489796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketorolac continuous
Description: Continuous (2 ml/hr): Ketorolac 180 mg + N/S 94 ml = total 100 ml
Study NCT05237193 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: The level of CIN
Description: The extracted DNA from bile will be analyzed by UCAD to determine the level of CIN. And the patient will be followed for up to 2 years.
Study NCT04817462 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Liver biopsy
Description: The study population is patients with either haemophilia A or B who have previously been administered gene therapy treatment in one of three specific gene therapy clinical trials. In this study they will have a liver biopsy performed to take up to 3 samples for laboratory analysis.
Study NCT05142618 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Physical Therapy
Description: The twice-per-week 8-week course of supervised physical therapy begins 2 weeks after surgery. It targets abdominal core function through progressive muscle retraining and strengthening, and patient-specific posture and body mechanics education.
Study NCT05142618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Post-operative Precautions
Description: This intervention includes standard of care post-operative instructions typically given to patients undergoing ventral hernia repair across the world. These include limiting strenuous physical activity and a lifting restriction of no more than 10 pounds for 6 weeks. Binder use is also encouraged for 4-6 weeks after the operation.
Study NCT05748834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tucatinib
Description: Participants will receive tucatinib 300mg by mouth twice daily continuously (days 1-28) of each 28 day cycle.
Study NCT05748834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxil
Description: Participants will receive Doxil 40mg/m2 intravenously on day 1 of each 28 day cycle (with a maximum cumulative dose of 550mg/m2).
Study NCT05770011 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intraoral scanner of nonsplinted scan bodies
Description: scanning of non splinted scan bodies
Study NCT05043558 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: beprostaglandin sodium
Description: beprostaglandin sodium
Study NCT05511519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATI-450
Description: Oral, small molecule MK2 inhibitor
Study NCT05511519 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Oral Tablet
Description: Placebo tablet manufactured to match ATI-450 in appearance
Study NCT05597670 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: traditional knee rehabilitation program
Description: Patients in this group will receive a traditional therapeutic knee rehabilitation program in the form of mini-squatting exercise (up to 45 degree knee flexion measured by a universal goniometer) , strengthening of hip abductors and external rotators
Study NCT05597670 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional knee rehabilitation program
Description: Patients in this group will receive a traditional therapeutic knee rehabilitation program in the form of mini-squatting exercise (up to 45 degree knee flexion measured by a universal goniometer) , strengthening of hip abductors and external rotators
Study NCT05597670 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: proximal stabilization
Description: the principles of proximal stability will be explained to patients before initiation of treatment and patients will be asked to comply with these principles during exercise. These principles include learning how to activate transversus abdominus by abdominal bracing without allowing pelvis tilting and ensure neutral spine and diaphragmatic breathing during exercise.
Study NCT05770011 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: impression material
Description: conventional recording
Study NCT05770011 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intraoral scanner of splinted scan bodies
Description: scanning of splinted scan bodies
Study NCT04880954 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Soft Tissue Mobilization
Description: Soft Tissue Mobilization will be provided to participants by Licensed Chiropractor focusing on structures of the lower and upper leg. This will be provided for 20 minutes, once per week for 12 weeks.
Study NCT04880954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Participants will engage in 20 minutes of prescribed at-home exercise 5 times per week, for 12 weeks.
Study NCT06168903 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound guided EOI block
Description: Before receiving general anesthesia, patients will be randomly assigned to one of the two study groups: the EOI block group or the ESPB group.~Using Ultrasound (Siemens ACUSON X300 Ultrasound System), guided blocks will be administered immediately after the induction of anesthesia and prior to surgical incision by consultant anesthesiologists who have experience in regional anesthesia and are familiar with the EOI and ESPB blocks
Study NCT06168903 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound guided EOI block
Description: Before receiving general anesthesia, patients will be randomly assigned to one of the two study groups: the EOI block group or the ESPB group.~Using Ultrasound (Siemens ACUSON X300 Ultrasound System), guided blocks will be administered immediately after the induction of anesthesia and prior to surgical incision by consultant anesthesiologists who have experience in regional anesthesia and are familiar with the EOI and ESPB blocks
Study NCT04890665 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Online psychological intervention for healthcare workers
Description: The intervention is based on Cognitive Behavioral Therapy, Mindfulness, Behavioral Activation Therapy, Acceptance and Commitment Therapy and Positive Psychology, aimed at the Psychoeducation regarding the manifestations of anxiety, depression, burnout, fatigue compassion, posttraumatic stress disorder, and affectations in sleep quality and perception of life quality in healthcare workers.~And 3 complementary modules that according to the scientific literature could affect the mental health of healthcare workers related to how to deliver bad health news, Psychological first aid and how beliefs could influence physical and emotional self-care in the face of the COVID-19 pandemic.
Study NCT04890665 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online psychological intervention for healthcare workers
Description: The intervention is based on Cognitive Behavioral Therapy, Mindfulness, Behavioral Activation Therapy, Acceptance and Commitment Therapy and Positive Psychology, aimed at the Psychoeducation regarding the manifestations of anxiety, depression, burnout, fatigue compassion, posttraumatic stress disorder, and affectations in sleep quality and perception of life quality in healthcare workers.~And 3 complementary modules that according to the scientific literature could affect the mental health of healthcare workers related to how to deliver bad health news, Psychological first aid and how beliefs could influence physical and emotional self-care in the face of the COVID-19 pandemic.
Study NCT05796791 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Hydrochloride
Description: IM ketamine given in weekly session for a total of 3 weeks
Study NCT05796791 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational enhancement therapy
Description: Brief motivational based therapy
Study NCT05841784 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MBCT-T
Description: MBCT-T is an 8-week group-based program that combines training in mindfulness and cognitive-behavioral therapy to reduce psychological distress and negative emotions. Each weekly 1-hour session will consist of a check-in, discussion, teaching, mindfulness or cognitive behavioral practice or exercise, inquiry by the facilitator, and summary of the at-home practice.
Study NCT05841784 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MBCT-T
Description: MBCT-T is an 8-week group-based program that combines training in mindfulness and cognitive-behavioral therapy to reduce psychological distress and negative emotions. Each weekly 1-hour session will consist of a check-in, discussion, teaching, mindfulness or cognitive behavioral practice or exercise, inquiry by the facilitator, and summary of the at-home practice.
Study NCT05583526 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ritlecitinib
Description: 50 mg capsule
Study NCT05583526 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching capsule
Study NCT04869436 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
Description: Dupilumab will be administered subcutaneously for 6 months (1 initial 600mg dose + 5 300mg doses every 4 weeks)
Study NCT06278987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PENG block and cryoablation
Description: will receive an ultrasound guided PENG block with 20 mL of 0.5% bupivacaine followed by cryoablation of the PENG nerves.
Study NCT06278987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fascia iliaca compartment block
Description: will receive an ultrasound guided fascia iliaca compartment catheter with initial bolus of 20 mL of 0.5% bupivacaine followed by infusion of 0.2% ropivacaine at 10 mL per hour
Study NCT06265532 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: EGCG 300 mg
Description: Participants will be administered EGCG as part of the phase I study: Dose ranging study of oral epigallocatechin-3-gallate (EGCG) given daily for 12 weeks to patients with Idiopathic Pulmonary Fibrosis (IPF) evaluating safety, PK interactions with standard of care drugs, and biomarkers of drug effect.
Study NCT06265532 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for EGCG 300 mg
Description: Participants will be administered placebo for EGCG as part of the phase I study: Dose ranging study of oral epigallocatechin-3-gallate (EGCG) given daily for 12 weeks to patients with Idiopathic Pulmonary Fibrosis (IPF) evaluating safety, PK interactions with standard of care drugs, and biomarkers of drug effect.
Study NCT06265532 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: EGCG 600 mg
Description: Participants will be administered placebo for EGCG as part of the phase I study: Dose ranging study of oral epigallocatechin-3-gallate (EGCG) given daily for 12 weeks to patients with Idiopathic Pulmonary Fibrosis (IPF) evaluating safety, PK interactions with standard of care drugs, and biomarkers of drug effect.
Study NCT06265532 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for EGCG 600 mg
Description: Participants will be administered placebo for EGCG as part of the phase I study: Dose ranging study of oral epigallocatechin-3-gallate (EGCG) given daily for 12 weeks to patients with Idiopathic Pulmonary Fibrosis (IPF) evaluating safety, PK interactions with standard of care drugs, and biomarkers of drug effect.
Study NCT05841784 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Booster Mindfulness Sessions
Description: Following the standard 8-week MBCT-T program, participants in certain arms will receive monthly MBCT-T booster sessions for 4 months of follow up. Each booster session will be 1 hour long. The sessions will include a concise review and summary of the main MBCT-T sessions.
Study NCT05841784 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Website Support
Description: Participants in certain arms will receive continuous intervention support via the use of an online study website. The website will provide quick access to intervention materials and support to encourage participants to complete the at-home practice and apply the content of the MBCT-T program to real life situations.
Study NCT05366387 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: intrapulmonary percussive ventilation
Description: Intrapulmonary percussive ventilation is a non invasive ventilation technique where small boli or air are delivered, at adjustable frequency and pressure, to the upper airways though a mouthpiece. IPV is currently used in the clinic to aid with airway clearance in neuromuscular and airway diseases.
Study NCT05366387 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: delivery of 99mTc-DTPA aerosol
Description: A 99mTc-DTPA aerosol (500 MBq+/-20%, 3 ml volume) is generated with a jet nebuliser (MMAD 4 µm). The aerosol is inhaled by the study subject and lung deposition is imaged by SPECT
Study NCT05366387 — intervention group
Intervention type: RADIATION
Group type: SHAM_COMPARATOR
Intervention: delivery of 99mTc-DTPA aerosol
Description: A 99mTc-DTPA aerosol (500 MBq+/-20%, 3 ml volume) is generated with a jet nebuliser (MMAD 4 µm). The aerosol is inhaled by the study subject and lung deposition is imaged by SPECT
Study NCT05288543 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IPG7236- Single ascending dose
Description: Subjects will receive IPG7236 tablets orally once on Day 1 in a fasted state
Study NCT05288543 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IPG7236- Multiple ascending dose
Description: Subjects will receive IPG7236 tablets orally once daily for 10 days from Day1 to Day 10 in a fasted state
Study NCT05288543 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Part A)
Description: Subjects will receive IPG7236 tablets orally once on Day 1 (Part A) or once daily for 10 days from Day1 to Day 10 (Part B) in a fasted state
Study NCT04795141 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABY-035
Description: ABY-035 Solution for injection
Study NCT04795141 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal Saline for injection
Study NCT05591131 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: genetic testing
Description: Undergo genetic testing
Study NCT05591131 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Complete survey
Study NCT06119724 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bipolar enbloc resection of bladder tumor
Description: Enbloc retrival of bladder tumor entoto using cystoscopy using bipolar
Study NCT06119724 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thulium laser enbloc resection of bladder tumor
Description: Enbloc retrival of bladder tumor entoto using cystoscopy using thulium laser
Study NCT04924205 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FM2 Knee Brace
Description: Participants in this group will use the FM2 Knee Brace for their post-TKA physical therapy.
Study NCT06433401 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transitional care training with brochures, posters and slide training materials
Description: Education at 3 and 6 months after the first interview
Study NCT05600738 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RNS/DBS activation
Description: This will be performed to study the EEG responses to DBS/RNS stimulation electrical pulses. The stimulation frequencies will be sequentially increased and each stimulation will last for 2 minutes.There will be a 1-2 minute wash out period after each trial.
Study NCT06125054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: single dose of ketamine (0.71mg/kg bodyweight i.v. over 40 minutes)
Study NCT05123716 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MDMA
Description: Participants will be given 100 mg of MDMA
Study NCT05123716 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo oral tablet
Description: Participants will be given a placebo capsule that will only contain lactose.
Study NCT06125054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: single dose of placebo (0.9% saline solution i.v. over 40 minutes)
Study NCT06125054 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: single dose of placebo (0.9% saline solution i.v. over 40 minutes)
Study NCT06125054 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: real-time fMRI neurofeedback training
Description: Real-time fMRI based neurofeedback over 20 minutes where participants are instructed to perform reward imagery. The feedback is based on an experimental region. The training is repeated three times.
Study NCT06125054 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sham real-time fMRI neurofeedback training
Description: Sham real-time fMRI neurofeedback training over 20 minutes where participants are instructed to perform reward imagery. The feedback is based on a control region. The training is repeated three times.
Study NCT06125054 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: sham real-time fMRI neurofeedback training
Description: Sham real-time fMRI neurofeedback training over 20 minutes where participants are instructed to perform reward imagery. The feedback is based on a control region. The training is repeated three times.
Study NCT05569473 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TEST GROUP: VCMX + OFD, CONTROL GROUP : OFD ONLY
Description: A full-thickness mucoperiosteal flap will be raised, no bone recontouring would be performed, Thorough debridement of the surgical site would be performed. For the test group, VCMX would be placed according to the dimensions of the intrabony defect after open flap debridement (OFD). For the control group, OFD will be done and After this, flaps would be approximated and sutured at the original position with a monofilament suture material using interrupted sutures.
Study NCT05269732 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group Cognitive Behavioural Therapy (CBT)
Description: The 9-week group Cognitive Behavioural Therapy (CBT) intervention for Postpartum Depression (PPD) delivered via Zoom by two trained psychologists. This intervention was developed by Dr. Van Lieshout (Principal Investigator) at the Women's Health Concerns Clinic (WHCC) at St. Joseph's Healthcare Hamilton. It was designed to be brief, simple, and applicable to women in community settings. It consists of 9 weekly 2-hour sessions where core CBT skills are learned and practiced each week. The first half of each session is devoted to core CBT content, including cognitive restructuring. The second half is devoted to group discussions co-led by participants on topics relevant to mothers with PPD (e.g., sleep, supports, role transitions). Homework is assigned at each session.
Study NCT05587842 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Early Weightbearing management post operation
Description: Subjects will be instructed to be weightbearing, as tolerated, on their ankle starting at two weeks post operation.
Study NCT05587842 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Delayed Weightbearing management post operation (Traditional)
Description: Subjects will be instructed to be non-weightbearing on their ankle until at least 6 weeks. After 6 weeks, the subject will be instructed to be weightbearing as tolerated.
Study NCT06496581 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 177Lu-PMSA-617
Description: Once every 6 weeks, 7400 MBq 177Lu-PMSA-617 will be administered for up to a total of 4 cycles.
Study NCT06496581 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: ADT, abiraterone and each ARSI (Apalutamide, Darolutamide, Enzalutamide) will be administrated according to the standard of care