AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04766346 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fortified Cow's Milk-Based Oral Nutritional Supplement
Description: The NS is a fortified cow's milk-based product provided in powdered form that provides the appropriate amount of energy and protein to promote growth in children.
Study NCT06089915 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard occupational therapy
Description: Standard occupational therapy as part of inpatient rehabilitation
Study NCT06089915 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard occupational therapy
Description: Standard occupational therapy as part of inpatient rehabilitation
Study NCT06089915 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robot-assisted exercise using Amadeo device and Armeo Spring exoskeleton
Description: Exercise for fingers and hand using Amadeo device plus gross-motor exercise using Armeo Spring exoskeleton
Study NCT05986279 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehab
Description: 6 weeks of vestibular rehabilitation guided by the MINDGAPS decision support system
Study NCT05441410 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyronaridine Tetraphosphate, Artesunate Drug Combination
Description: Combination drug for treatment of uncomplicated malaria
Study NCT05441410 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PfSPZ Challenge (NF54)
Description: cryopreserved Plasmodium falciparum sporozoites injected by intravenous inoculation
Study NCT05441410 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MVA ME-TRAP
Description: virally vectored subunit vaccine candidates where ME-TRAP is expressed by the non-replicating viral vector Modified Vaccinia Ankara (MVA)
Study NCT05441410 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ChAd63 ME-TRAP
Description: virally vectored subunit vaccine candidates where ME-TRAP is expressed by the non-replicating viral vector Chimpanzee Adenovirus 63 (ChAd63)
Study NCT05441410 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Sodium chloride (NaCl) 0.9%
Description: 0.9% NaCl solution for injection
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gabapentin 600 mg
Description: Participants will receive a single oral dose of gabapentin 600 mg and a placebo that looks like oxycodone HCl
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gabapentin 1200 mg
Description: Participants will receive a single oral dose of gabapentin 1200 mg and a placebo that looks like oxycodone HCl
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gabapentin 600 mg and oxycodone HCl 20 mg
Description: Participants will receive a single oral dose of gabapentin 600 mg and oxycodone HCl 20 mg
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gabapentin 1200 mg and oxycodone HCl 20 mg
Description: Participants will receive a single oral dose of gabapentin 1200 mg and oxycodone HCl 20 mg
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: oxycodone HCl 20 mg
Description: Participants will receive a single oral dose of oxycodone HCl 20 mg and a placebo that looks like gabapentin
Study NCT05319756 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Participants will receive a single oral dose of a placebo that looks like gabapentin and a placebo that looks like oxycodone HCl
Study NCT05449925 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Injectable PRF and Microneedling
Description: i-PRF and Microneedling Procedure in thin gingiva followed by orthodontic treatment
Study NCT06093724 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Static and dynamic perineo-pelvic MRI
Description: Static and dynamic perineo-pelvic MRI before surgery, and at 6 and 24 months after surgery.
Study NCT05289037 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1273.617.2
Description: Lipid nanoparticle (LNP) dispersion containing an mRNA that encodes for the prefusion stabilized S protein of the B.1.617.2 (Delta) variant SARS-CoV-2 strain.
Study NCT05289037 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sodium Chloride, 0.9%
Description: 0.9% Sodium Chloride Injection
Study NCT05393375 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT05902286 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: OSC+
Description: The first session of the HRVB intervention will focus on introducing the client to HRVB and calculating the participant's resonance frequency which typically range from 4.5-7 breaths per minute. Participants will first complete a five-minute baseline breathing condition. Following the breathing condition, the participants will complete five conditions for five minutes each. Specifically, each condition will have the person breath at 6, 6.5, 5.5, 5, and 4.5 breaths per minute with a minute break between. Session two will focus on practicing resonance frequency breathing and solidifying the correct resonance frequency for the participant. Additionally, this session will introduce the technique of breathing through pursed lips and abdominal breathing. For sessions three through five, participants will practice resonance frequency breathing and review previous strategies.
Study NCT05902286 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: OSC-
Description: During the first week, the baseline will be assessed and resonance frequency. Specifically, during their first intervention session the participants will be told that the goal of the sessions includes decreasing heart rate variability and avoiding slow and steady breathing. The participants will then be asked to choose five strategies to lower their heart rate oscillations. Participants will be told to avoid slow breathing as it causes large heart rate oscillations. For the second session, the therapist will check in with the participant and discuss how the practice went. Participants will then select three strategies that they will practice for three five-minute conditions following a five-minute baseline. Sessions three, four, and five will include three conditions: a five-minute baseline and two strategies of their choice. For each session, the best strategy will be calculated and written on the assignment sheets to be used during the week for their four homework sessions.
Study NCT05881824 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: MDG intervention
Description: 6-month behavioral intervention aiming at weight loss and increasing adherence to the Mediterranean diet
Study NCT05274906 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Randomized, cross-over controlled feeding trial testing a Healthy Eating Index 2015 (HEI-2015) diet with and without red and processed meat
Description: Healthy Eating Index-2015 (HEI-2015) with or without red/processed meat (HEI-2015-M)
Study NCT06567496 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: First Resort
Description: First Resort is an 8-week, self-guided, at-home, virtual reality program designed to be used as an intervention to help manage stress, worry, and sadness. It is grounded on evidence-based cognitive behavioral therapy and acceptance and commitment therapy techniques, including psychoeducation, mindfulness, behavioral activation through values clarification and goal setting, and cognitive reframing to identify and reframe cognitive distortions.
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab-paclitaxel
Description: 1. Patients will receive treatment Day 1 and Day 15 of each cycle (28 days).~2. Nab-paclitaxel (80 mg/m2) will be administered IV on Day 1 and Day 15 (28 day cycle).~3. Other Name: Abraxane
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: 1. Patients will receive treatment Day 1 and Day 15 of each cycle (28 days).~2. Gemcitabine (500mg/m2) will be administered IV on Day 1 and Day 15 (28 day cycle).~3. Other Name: Gemzar
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: 1. Patients will receive treatment Day 1 and Day 15 of each cycle (28 days).~2. Cisplatin (20mg/m2) will be administered IV on Day 1 and Day 15 (28 day cycle).~3. Other Name: N/A
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: 1. Patients will receive treatment Day 1 and Day 15 of each cycle (28 days).~2. Irinotecan (20 mg/m2) will be administered IV on Day 1 and Day 15 (28 day cycle).~3. Other Name: N/A
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1. Patients will receive treatment Day 1-7 and Day 15-21 of each cycle (28 days).~2. Capecitabine (500 mg) will be administered orally twice a day on days 1-7 and 15-21 of each cycle (28 days).~3. Other Name: Xeloda
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 1. Patients will receive treatment Day 1 every other cycle (every 6 weeks) (28 days) during maintenance phase.~2. Pembrolizumab (400 mg) will be administered IV on day 1 every other cycle (every 6 weeks).~3. Other Name: MK-3475; Keytruda
Study NCT04753879 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: 1. Patients will receive treatment on Days 1-21 during the maintenance phase.~2. Olaparib (300 mg) will be administered orally twice a day on Days 1- 21 of each cycle (28 days).~3. Other Name: Lynparza
Study NCT06085586 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early Weight Bearing
Description: Full weight bearing (100%) initiated at 4 weeks postoperatively
Study NCT06085586 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Normal Weight Bearing
Description: Full weight bearing (100%) initiated at 6 weeks postoperatively
Study NCT05964400 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: duoABLE
Description: Stroke participant-caregiver duos (dyads) will meet with an occupational therapist 12 times (2x/week for 6 weeks, approximately 30 minutes/session) to apply activity monitoring, activity scheduling, collaborative problem solving, self-assessment, and social interdependence to self-selected activities that aim to increase both dyad members' physical activity levels
Study NCT06163898 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alnuctamab
Description: Specified dose on specified days
Study NCT06163898 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mezigdomide
Description: Specified dose on specified days
Study NCT06163898 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Specified dose on specified days
Study NCT05006313 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraoperative fluorescence angiography
Description: Intraoperative fluorescence angiography will be used to assess tissue perfusion following initial debridement of wound.
Study NCT05543629 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BMS-986442
Description: Specified dose on specified days
Study NCT05543629 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified dose on specified days
Study NCT05543629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Specified dose on specified days
Study NCT05543629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Specified dose on specified days
Study NCT05543629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemexetred
Description: Specified dose on specified days
Study NCT05543629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Specified dose on specified days
Study NCT05570721 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trier Social Stress Test
Description: The TSST has both social-evaluative and arithmetic components. During the social-evaluative component, the participant is asked to prepare and then deliver a brief speech to the research team. After this component there is a surprise arithmetic problem. This challenge paradigm has been well-established to rapidly and robustly induce psychological stress as well as physiological indices of stress (e.g., cortisol response, heart rate response). This task takes approximately 15 minutes to complete.
Study NCT05285553 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MiSight 1 Day
Description: Part 1 of the study - subjects will be randomized to wear MiSight 1 Day for three years.
Study NCT05285553 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Proclear 1 day
Description: Part 1 of the study - subjects will be randomized to wear Proclear 1 day for three years.~Part 2 of the study - All the subjects will wear Proclear 1 day lenses for one year.
Study NCT05843253 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ribociclib
Description: Ribociclib PO qd on days 1-21
Study NCT05843253 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Everolimus
Description: Everolimus PO qd on days 1-28
Study NCT05364164 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-L01 12.5/1,000 mg
Description: FDC tablet, 2 tablets at a time, oral administration, dosing under fasting condition
Study NCT05364164 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT-L01 12.5/1,000 mg
Description: FDC tablet, 2 tablets at a time, oral administration, dosing after high-fat meal
Study NCT06421662 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attachment Training
Description: The study group was trained online by a psychologist on attachment in two sessions. In order to measure the level of attachment knowledge before and after the training, a test form prepared by the researcher based on the literature and expert opinion was used as pre-test and post-test. In the 8th week after delivery, Maternal Attachment Inventory  developed by Mary Muller in 1994 and Turkish validity and reliability study was conducted by Şirin and Kavlak.
Study NCT05865002 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AUR107
Description: Once daily
Study NCT05654116 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiver Interaction Profile (CIP) training
Description: The CIP training aims to boost six interactive skills in daycare providers: sensitive responsiveness, respect for children's autonomy, structuring and limit setting, verbal communication, developmental stimulation, and fostering positive peer interactions. The training takes place with 1 or 2 daycare providers at a time, and consists of 5 or 6 weekly sessions, respectively. In individual trainings, sessions 1-3 focus on two skills each, session 4 is a recap of two skills the daycare provider chooses, and the final session is shared with a colleague. In pairwise sessions, session 1 focuses on the first two skills, sessions 2-5 each focus on one skill, and the last session serves as a recap of two skills the daycare providers choose. The training uses a video-feedback method: daycare providers are filmed in interactions with children in daycare, the CIP trainer preselects relevant fragments of video recordings to discuss with the daycare provider(s) during the training sessions.
Study NCT06325072 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Conclusive genetic testing
Description: Patients will be referred for genetic counseling at the study coordinating center. This will lead to a conclusive genetic diagnosis.
Study NCT06325072 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Genotype-phenotype correlation for personalized diagnosis
Description: Patients and their family members will undergo a thorough clinical reassessment at the study coordinating center to identify diagnostic handles of the suspected disease based on the genetic test result (reverse phenotyping). The clinical reassessment could include the performance of additional clinical and instrumental tests, as well as other specialized consultations. This will lead to a conclusive genetic diagnosis in a substantial proportion of cases, cases, who will then be provided with genetic counselling.
Study NCT06325072 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Personalized study of variants of uncertain clinical significance (VUS) through functional studies on 3D organ-on-a-chip
Description: The investigators will perform functional assessment trough urine derived Renal Progenitor Cells (u-RPC) to establish the role of variants in determining the clinical phenotype.
Study NCT04205526 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active rTMS
Description: Patients randomized to receive actual rTMS treatment will receive 1Hz rTMS applied over contralesional M1 at an intensity of 120% resting motor threshold once daily for 30 minutes (approximately 1800 pulses) for a total of 15 sessions.
Study NCT04205526 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham TMS
Description: For sham-stimulation, the TMS coil will be placed over the inter-hemispheric fissure at the vertex and stimulation will be performed with low intensity (10% resting motor threshold). This will cause similar skin sensations as real stimulation but will not induce currents in motor relevant areas.
Study NCT06334887 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of esTOCma
Description: Participants of the experimental group will use the esTOCma mobile app until completion, within a set period of 10 days.~EsTOCma is a a serious game with 10 missions where users have to free 10 characters who have been imprisoned by a monster called esTOCma, which metaphorically represents the stigma in OCD. With each mission, users will gain knowledge about OCD and free an imprisoned character until the tenth mission, when they will defeat the monster. This game has three modules: (1) Psychoeducation (missions 1-5), where general information about OCD, OCD treatments and where to seek help is provided; (2) Indirect Contact (missions 6 and 7), which consists of a series of audio-visual recordings in which OCD patients report their symptoms and the impact the disorder has had on their lives; and finally, (3) Cognitive Restructuring (missions 8-10), where common dysfunctional beliefs about OCD and OCD treatment are challenged.
Study NCT05727813 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: cryoablation
Description: cryoablation of breast cancer smaller than 2 cm
Study NCT05234957 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bilateral Lateral Rectus Recession
Description: Symmetric bilateral lateral rectus muscle recession involves equal recession of both lateral rectus muscles. Asymmetric bilateral lateral rectus muscle recession involves recession of the lateral rectus muscle by 2mm more in the non-dominant eye.
Study NCT05826067 — intervention group
Intervention type: OTHER
Intervention: collection of bacterial strains
Description: Urine (and blood) samples will be collected following SOC procedures for diagnostic purposes, at each visit of the patient (initial visit, follow up study or visit for new episode. For patients needing a catheter, urine sample will be collected before the insertion of the catheter, and before renewal of the catheter. Catheter tips will also be collected and sonicated to isolate bacteria. E. coli will be stored for analysis.
Study NCT04917965 — intervention group
Intervention type: OTHER
Intervention: Laboratory clotting studies
Description: Cord blood will be utilized to perform lab test including PT, aPTT, fibrinogen, platelet count, platelet mapping, and TEG6s
Study NCT06161129 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Lenses
Description: The filter lenses will be worn by participants for one month all day.
Study NCT05663333 — intervention group
Intervention type: OTHER
Intervention: Dynamic full-field optical coherence tomography analysis of temporal artery biopsy
Description: Dynamic full-field optical coherence tomography analysis of temporal artery biopsy in the dermatology department before conventional histopathological analysis
Study NCT05344391 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: BFR cycling
Description: Cycling with BFR followed by shoulder exercises
Study NCT05344391 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cycling without BFR
Description: Cycling without BFR followed by shoulder exercises
Study NCT05245461 — intervention group
Intervention type: OTHER
Intervention: Assessments
Description: Muscle Strength, Proprioception, Kinesiophobia
Study NCT05028374 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: A single booster dose of the Moderna mRNA COVID-19 vaccine
Description: All participants will receive a single dose of the Moderna mRNA COVID-19 vaccine administered intramuscularly. This is an open label, non-randomized trial.
Study NCT05127109 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Nutrition Ecosystem pathway
Description: 1. parenteral nutrition initiated within 72 hours of operative intervention~   * Provided as clinically appropriate: Ensure Enlive, Ensure High-Protein, Nepro with Carb-Steady/ProSource Gelatein Plus, and/or ProSource Gelatein Plus~2. metabolic cart assessments to determine resting energy expenditure (REE) and guide registered dietitians (RDs)~   * Q-NRG Metabolic Cart (Indirect Calorimeter) and Quark RMR Metabolic Cart (Indirect Calorimeter)~  * BWA 2.0 Advanced Bioelectric Impedance Spectroscopy (BIS)~  * Philips Lumify L12-4 broadband linear array transducer ultrasound~3. expedited delivery of oral nutrition supplements and~4. a team-based approach on proper documentation of nutrition delivery and intake
Study NCT05127109 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Comparator
Description: retrospective cohort of 300 historical matched control subjects