AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04752579 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercise program
Description: The program will be individually supervised and will be conducted twice a week at the physiotherapy center.~• Slow execution of 7-10 repetitions of the following Pilates exercises: Pelvic Curl, Pilates Single Legs Lifts \& Leg Change, Twist Supine Pilates exercise, Chest Lifts Pilates Exercise, Chest Lift with Rotation Pilates exercise, 100's Prep Pilates Exercise, Single Leg Stretch Pilates Exercise, Front Support Pilates Exercise and Basic Back Extension Pilates Exercise. After the 6th week, while the person will be familiar with the basic exercises of the Pilates method the following exercises will be added: Leg Pull Front, Side Bend Pilates Exercise, Sphinx - Abdominal Lift Pilates Exercise, Shoulder Bridge Prep Pilates and Shoulder Bridge Pilates Exercise. Each session will be completed with breathing exercises and stretching exercises of the torso and lower limbs for 5 minutes.
Study NCT05224869 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medical Device Usage and Evaluation
Description: Undergo hydrogel rectal spacer placement
Study NCT05224869 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CT simulation
Description: CT simulation of radiation treatment planning 2-7 days after hydrogel placement
Study NCT05224869 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiation therapy
Description: SBRT in 5 fractions over 1 week, 7 days after CT simulation
Study NCT05224869 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Brachytherapy
Description: one month after completing SBRT
Study NCT05224869 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Post-implant dosimetry scan
Description: one month after brachytherapy
Study NCT06193070 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Play virtual misinformation escape room game
Study NCT06193070 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Ancillary studies
Study NCT06193070 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT06193070 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telemedicine
Description: Play virtual misinformation escape room game
Study NCT05136755 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NMDAE
Description: Use of an NMDA enhancer for the treatment of antidepressant nonresponders with MDD
Study NCT05136755 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Cap
Description: Use of placebo as a comparator
Study NCT05663801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Use of Bupivacaine in pectoral nerve block in mastectomy
Description: Pectoral nerve block will be performed and patients will be given 30 mL of 0.25% bupivacaine hydrochloride and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles
Study NCT05663801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: use of Ketamine as adjuvants to bupivacaine in pectoral nerve block in mastectomy
Description: Pectoral nerve block will be performed and Patients will be given 30 mL of 0.25% bupivacaine hydrochloride plus ketamine hydrochloride (1 mg/kg) and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles
Study NCT05663801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Use of Magnesium Sulfate as adjuvants to bupivacaine in pectoral nerve block in mastectomy
Description: Pectoral nerve block will be performed and Patients will be given 30 mL 0.25% Bupivacaine hydrochloride plus Magnesium Sulfate ( 28 ml Bupivacaine 0.25% plus 2ml magnesium sulfate 50%) and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles
Study NCT04990583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Face-to-Face PrEP Adherence Intervention Based on LifeSteps
Description: This single session intervention, based on LifeSteps, will occur with a study adherence coach either in-person or remotely via HIPAA compliant videoconferencing software. The topics covered during the session will include: experience taking PrEP, risk behavior education, mental health and substance use as barriers to adherence, other barriers to adherence, formulating a dosing schedule, storing and transporting medications, and response to slips in adherence. Participants assigned to the Carium condition will also receive an introduction to the Carium app.
Study NCT04990583 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Face-to-Face PrEP Adherence Intervention Based on LifeSteps
Description: This single session intervention, based on LifeSteps, will occur with a study adherence coach either in-person or remotely via HIPAA compliant videoconferencing software. The topics covered during the session will include: experience taking PrEP, risk behavior education, mental health and substance use as barriers to adherence, other barriers to adherence, formulating a dosing schedule, storing and transporting medications, and response to slips in adherence. Participants assigned to the Carium condition will also receive an introduction to the Carium app.
Study NCT04990583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Adherence Coaching Facilitated by Carium Adherence App
Description: The Carium app will be used to deliver medication reminders to participants, track medication adherence, engage in two-way secure messaging with participants, and connect with participants through a secure video feature. The adherence coach will use the secure messaging feature to support the participant with their adherence
Study NCT05707975 — intervention group
Intervention type: OTHER
Intervention: Identifying a relationship between the intensity of eco-anxiety and the severity of suicide risk in adolescents
Description: Relationship between the intensity of eco-anxiety with the 13-item CAS score, and the seriousness of the suicide risk with the C-SSRS score
Study NCT03907982 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: DC Cardioversion
Description: DC cardioversion (DCCV) is used to treat irregular heart rhythms (commonly atrial fibrillation). The procedure involves sedation or anaesthetic and placement of electrodes on the chest. An electrical impulse is passed across the electrodes to return the heart rhythm to normal.
Study NCT03907982 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: DC Cardioversion
Description: DC cardioversion (DCCV) is used to treat irregular heart rhythms (commonly atrial fibrillation). The procedure involves sedation or anaesthetic and placement of electrodes on the chest. An electrical impulse is passed across the electrodes to return the heart rhythm to normal.
Study NCT03907982 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary vein isolation
Description: The cryoballoon (CE marked) is the key specified technique for performing pulmonary vein isolation in the ablation arm in this trial. This allows the physician electrophysiologist to perform a circumferential freeze around the pulmonary veins to electrically isolate the vein, thus preventing pulmonary vein ectopy from triggering AF.
Study NCT03907982 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implantable loop recorder
Description: The Reveal device is inserted in the pre-pectoral position under the skin. This is performed with local anaesthetic and sedation at the end of the procedure clinic by the electrophysiologist performing the procedure. The device will provide a continuous recording of the heart rhythm and rate, and will be able to down load duration of AF episodes via a home monitoring system to establish the primary endpoint of the study.
Study NCT03907982 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implantable loop recorder
Description: The Reveal device is inserted in the pre-pectoral position under the skin. This is performed with local anaesthetic and sedation at the end of the procedure clinic by the electrophysiologist performing the procedure. The device will provide a continuous recording of the heart rhythm and rate, and will be able to down load duration of AF episodes via a home monitoring system to establish the primary endpoint of the study.
Study NCT05369117 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: indocyanine green labeled fluorescent laparoscopy
Description: indocyanine green fluorescence labeling was performed under gastroscope before surgery and internal jugular vein puncture was performed routinely for better fluid replenishment after surgery
Study NCT06545214 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Video-EEG monitoring
Description: Video-EEG monitoring
Study NCT06545214 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Respiratory monitoring and polysomnography
Description: heart rate, pulse oximetry (oxygen levels in the blood), nasal airflow, respiratory effort (thoracic and abdominal) and capnography (carbon dioxide (CO2) levels in exhaled air)
Study NCT05728671 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IP2015
Description: Test drug
Study NCT05596968 — intervention group
Intervention type: DRUG
Intervention: Sorafenib
Description: The initial dose of sorafenib is 400 mg orally twice daily and is adjusted in case of suspected toxicity or resistance (dose range, 200-800 mg daily).
Study NCT06545214 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: 1 Hypercapnic challenge while participant is awake
Description: The healthy patient/subject breathes through the mouth, using a mouthpiece and a nose clip, through a device fitted with a hermetically sealed bag that measures the various parameters of his/her breathing. At the start of the test, the healthy patient/subject breathes ambient air and his or her breathing is measured. Then, after a few minutes, the healthy patient/subject is connected to the bag, breathing in a closed circuit. This causes a gradual increase in carbon dioxide (CO2) in the inspired air. During this time, breathing parameters will be measured and gas exchanges studied with each breath. The test is stopped when the end-tidal carbon dioxide pressure (PetCO2) reaches 60 mm Hg, or in the event of intolerance.
Study NCT05834803 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Renal artery stenting
Description: Optimal medical therapy and percutaneous transluminal renal angioplasty with stent placement.
Study NCT05834803 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham treatment
Description: Optimal medical therapy and sham treatment.
Study NCT06545214 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: 2 Hypercapnic challenges while participant is sleeping
Description: In the evening, as soon as the doctor detects on the EEG that the patient/subject is in deep sleep, various tests will be carried out to assess reactivity to wakefulness.~Two hypercapnic challenges will be carried out during sleep, using the same procedure as for wakefulness. The test will be stopped when the healthy patient/subject wakes up, or when the end-tidal carbon dioxide pressure (PetCO2) reaches 60 mm Hg, or in case of intolerance.
Study NCT06545214 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Auditory stimulus
Description: Two auditory stimulus tests will be carried out during the patient's sleep. Using headphones, the investigator will administer auditory stimuli at regular, progressively louder intervals to determine the ability of the patient/ healthy subject to awaken to an auditory stimulus.
Study NCT04913961 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supine Daoyin
Description: During hospitalization, the rehabilitation group will receive conventional western medicine treatment and supine guidance therapy which consists of training and patient education. They will be evaluated with some tests for the study
Study NCT04913961 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: western medicine conventional therapy
Description: The control group will get the western medicine conventional therapy with some additional tests for the study.
Study NCT05288868 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention: online didactic lecture and educational simulation activity
Description: The didactic was created by the research team and provides information on Autism Spectrum Disorder (ASD) and an approach to taking vital signs in these children. The didactic will be pre-recorded and sent by email to employee study participants. The didactic will last about 10 minutes.~The simulation activity will have the premise of a child with ASD and their caregiver at clinic visit. The employee participant will be asked to take vital signs on the patient. The caregiver will be played by an actor and the child will be played by a mannequin. An iterative script will be used by the actor during the scenario. The simulation will last about 20 minutes and will be followed by a 10 minute debrief.
Study NCT06545214 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaires
Description: Questionnaire to assess caffeine consumption habits Quality of life questionnaires QOLIE-31 Anxiety and depression questionnaires HADS
Study NCT06141187 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Vertebroplasty
Description: PVP
Study NCT06141187 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham Vertebroplasty
Description: Sham PVP
Study NCT04826068 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Emotional Processing
Description: Processing Emotions of others based on photographs of faces
Study NCT04826068 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Processing
Description: Processing Emotions of others based on photographs of faces
Study NCT06076369 — intervention group
Intervention type: PROCEDURE
Intervention: The tubular adenoma group
Description: Biopsy or removal of polyps for pathological examination. Collect baseline data such as gender, age, BMI, etc. If the pathology confirms a pure tubular adenoma, the observed object will be included in the group for final comparative analysis.
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Low-field magnetic resonance imaging
Description: Functional and morphologic imaging of the lungs
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Low-field magnetic resonance imaging
Description: Functional and morphologic imaging of the lungs
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Nailfold capillaroscopy
Description: Imaging of nailfold microvasculature
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Nailfold capillaroscopy
Description: Imaging of nailfold microvasculature
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Spiroergometry
Description: Cardiopulmonary exercise testing
Study NCT05286632 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KidneYou APP
Description: KidneYou is a medical device designed to deliver digital therapy (DT) to patients. The DT utilizes high quality digital technologies to stimulate lifestyle changes in patients. KidneYou has been set up to improve the commitment of patients in following therapeutic directives (i.e. nutritional programs, daily/weekly physical activities) to manage their chronic diseases like CKD. Moreover, KidneYou can improve patient's awareness about his/her disease (mindfulness) so as to increase the individual human ability to be fully present at the ongoing disease's condition and react to it in active and positive manner. Particularly, the mindfulness program contained in this App has been designed to increase the patient's psychological and mental health, aiming at decreasing the perceived stress due to the underlying disease and to the attempts of life-style changes (i.e., healthy diet and physical activity) which may initially negatively affect the subject's natural attitudes.
Study NCT05149313 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lebrikizumab
Description: Lebrikizumab solution for injection administered subcutaneously.
Study NCT05149313 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lebrikizumab-matching Placebo
Description: Matching Placebo solution for injection administered subcutaneously.
Study NCT05800977 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Prizloncabtagene autoleucel
Description: Prizlon-cel is a novel 2nd generation 4-1BB bispecific chimeric antigen receptor T-cell (CAR-T) targeting both CD19 and CD20 antigens
Study NCT06553534 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SAMURAI PICU Bundle
Description: The proposed multifaceted SAMURAI PICU Bundle is an intervention with the following core elements: 1) PICU Warning Tool: an automated clinical decision support (CDS) tool to provide a non-interruptive interprofessional predictive alert, 2) twice daily safety huddles with unit leadership, and 3) bedside assessment including the care team and patient's family to complete and display a bedside mitigation plan to prevent deterioration. This intervention combines the automated accurate prediction of the PICU Warning Tool with the use of provider intuition or a gut feeling from huddles to improve decision making at the bedside. Peripheral elements and possible adaptations will be suggested during Aim 1 and additional peripheral elements may be added by local sites after discussion with the PI through a user-centered design approach.
Study NCT06030635 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Measurement of compartment compressibility using the CPMX1 device
Description: Patients will be monitored about every hour (+/- 30 min) for a total of 8 hours. Measurement time might be extended in case the patient undergoes trauma-related surgery during the measurement period and/or in case measurements are spaced further apart. Remaining measurements will be completed after the surgery. At each time point, three measurements of compartment compressibility will be conducted using the CMPX1 on both the affected (potential ACS) and healthy limb.
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spiroergometry
Description: Cardiopulmonary exercise testing
Study NCT05742672 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ABDOMINAL MASSAGE APPLICATION
Description: * Experiment group twice a day in the morning and evening and 30 minutes after the feeding meal, for 15 minutes. For a period of time, effusion, petrissage, vibration massage movements will be applied by the researcher in accordance with the procedure (Abdominal Massage Application Directive). The application will continue for 7 days.- On the 3rd day (short term), 5th day (mid term) and 7th day (long term) to the massaged experimental group, the Constipation Severity Scale (CQS) and the Constipation Quality of Life Scale (QQQL) will be administered to determine the effect.~* Day 7 Rome Ш Constipation Diagnostic Criteria (Annex: 2) will be applied again and the patient's constipation status will be evaluated for the last time.~* Routine treatment and care practices in the clinic will continue.
Study NCT04907006 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SY-004 capsule
Description: After fasting for 10 hours, subjects in group 1 took one SY-004 (80mg) orally on an empty stomach on the day of administration with 240ml warm water; Subjects in group 2 began to eat high-fat breakfast 30 minutes before administration , and took one SY-004 capsule（80mg） orally with 240ml warm water. The subjects in both groups were fasted within 4 hours after taking the medicine, and drinking water was forbidden within 1 hour before and after taking SY-004.
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Realtime deformability cytometry
Description: High-throughput measurement of cell deformability and physical properties
Study NCT05445531 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Realtime deformability cytometry
Description: High-throughput measurement of cell deformability and physical properties
Study NCT05431517 — intervention group
Intervention type: PROCEDURE
Intervention: Analysis of ERCP records
Description: Data will be extracted from ERCP records of stenting, mainly including: 1) Age at the time of ERCP; 2) Gender; 3) Indication; 4) Papilla selection (major or minor); 5) Whether endoscopic sphincterotomy (EST) was performed; 6) Presence of nipple diverticulum; 7) Morphology of the pancreatic duct; 8) Status of pancreatic duct stones; 9) Number, shape, material, diameter and length of the stent; and 10) Operation of the bile duct. Additional data were extracted from the pertinent ERCP records of stent migration: 1) Shape, material, diameter and length of the displaced stent; 2) Type of migration; and 3) Removal tools.
Study NCT06139679 — intervention group
Intervention type: PROCEDURE
Intervention: ASD closure with fenestrated/non-fenestrated patch
Description: A PTFE patch is used to surgically close the interatrial defect. If closure with fenestrated patch is deemed necessary, a small opening is created on the patch
Study NCT05621824 — intervention group
Intervention type: DEVICE
Intervention: Endoscopic ultrasound
Description: Use endoscopic ultrasound to examine the pancreatic lesions.
Study NCT05621824 — intervention group
Intervention type: PROCEDURE
Intervention: EUS-Fine needle aspiration
Description: If solid mass of pancreas was found during EUS, EUS-FNA shall be conducted for diagnosis.
Study NCT05618496 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sodium Hyaluronate Lyophilizate
Description: Device is placed directly onto the treated wound. The wound should be cleaned with antiseptic solution prior to the device administration. The device is fixed on the wound by secondary dressing: e.g. plaster, compression.