AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05347212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Relatlimab
Description: Given by IV
Study NCT05831020 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: VAC and bolster dressing
Description: Bolster dressing- Moist bulky cotton gauze dressing and wrapped with cotton bandage.~Vacuum assisted closure (VAC) dressing- A fenestrated tube placed between two sheets of sterilized foam secured to the surrounding skin using adhesive dressing (OPSITE).
Study NCT05607979 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lavior Diabetic Wound Gel
Description: Daily application of hydrogel treatment for 60 days.
Study NCT05607979 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Smith & Nephew Solosite Gel Hydrogel Wound Dressing
Description: Daily application of hydrogel treatment for 60 days.
Study NCT05280132 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Personalized antibiotic treatment
Description: Personalized antibiotic treatment based on mPCR results, PCT (values and kinetics) and appearance of sputum.
Study NCT05280132 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual antibiotic treatment
Description: The antimicrobial therapy is left at the discretion of the physicians, as in usual practice.
Study NCT05193643 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sonovein Treatment
Description: The Sonovein System provides High Intensity Focused Ultrasound (HIFU) ablation of soft tissue. The energy is delivered via an extra-corporeal treatment probe, which includes an imaging system. The high-energy ultrasound waves propagate through the skin and are focused on a portion of the target tissue, generating intense heat and causing local cell apoptosis and progressive tissue volume reduction over the following months in the tissue within the focal area. The process is then repeated in a stepwise fashion to destroy the targeted tissues.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Articulating laparoscopic instrument
Description: The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Articulating laparoscopic instrument
Description: The Artisential articulating laparoscopic instrument will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional laparoscopic instrument
Description: Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional laparoscopic instrument
Description: Conventional laparoscopic instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Robotic surgical instrument
Description: Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06050161 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Robotic surgical instrument
Description: Robotic surgical instruments will be evaluated for efficacy and safety in suturing during minimally invasive gynecologic surgery.
Study NCT06130553 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD3470
Description: AZD3470 is a novel, potent and selective, second-generation, MTAP-selective, inhibitor of PRMT5.
Study NCT05911269 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TiMBRe
Description: 1 \& 2 Music Listening~* Live music played by the music therapist (e.g., guitar, voice) and AYA selected music will be used to facilitate attention to the present moment and provide cues for breathing/relaxation.~  3 \& 4 Music Facilitated Breathing~* The therapist will lead participants in music facilitated breathing exercises using rhythmic features of the music to cue structured breathing for relaxation and self-awareness~  5 \& 6 Music Facilitated Progressive Muscle Relaxation for Stress Reduction~* Using music as a structured auditory cue for tensing and releasing of muscles.~  7 \& 8 Body Percussion~* The therapist will lead participants in a hands-on body percussion activity to bring attention to the sound of rhythm, sensation in their hands and body.
Study NCT05911269 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Standard of care study staff calls and cancer survivorship resources
Study NCT04506879 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Popliteal Sciatic nerve block
Description: Patients schedule for lower limb surgery under regional anesthesia will receive ultrasound guided subparaneural popliteal sciatic nerve block. After identification of the common peroneal nerve and tibial nerve, local anesthetic agents will be injected close to each nerve below the point of divergence at the popliteal fossa. The spread of the drug and the sensory and motor function of that limb will be assessed regularly till it is ready for surgery.
Study NCT05974891 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilot application
Description: Pilot application will be carried out with at least 10 students. A pre-test will be applied to the experimental group. After the scales are applied, the experiment will be applied to the experimental group with the Geriatric Medication Game simulation.~Students simulating the elderly patient role during this simulation will gain a better understanding of age-related health problems and how older adults feel when confronting them. After the application, debriefing, which is the last stage of the simulation training, will be done to evaluate the application. After the application and analysis session is completed, the post-test will be applied to the experimental group. A 3-week clinical practice will be planned for the students in the experimental groups in order to evaluate the continuation of the acquired skills and acquired awareness. In this application, students will be asked to care for the elderly patient and the pre-test will be repeated at the end of the application.
Study NCT06437548 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous spinal cord stimulation
Description: The parameters of percutaneous cervical spinal cord stimulation leads will be adjusted for optimal upper extremity motor function.
Study NCT05498025 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deterra activated charcoal pouch
Description: drug disposal pouch
Study NCT06082349 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lymphaticovenous anastomosis
Description: Lymphaticovenous anastomosis (LVA) involves connecting a lymphatic vessel to a adjacent vein of similar size, thereby facilitating the ouflow of lymphatic fluid in patients suffering from secondary lymphedema
Study NCT06082349 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham surgery
Description: Sham surgery involves the process of surgery, including local anesthesia and incisions, but no LVA is made.
Study NCT06104891 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Recharge Placebo Control 1
Description: Participants will use their Radicle Recharge Placebo Control 1 as directed for a period of 5 hours.
Study NCT06104891 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 1
Description: Participants will use their Radicle Recharge Active Study Product 1 as directed for a period of 5 hours.
Study NCT06104891 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 2
Description: Participants will use their Radicle Recharge Active Study Product 2 as directed for a period of 5 hours.
Study NCT06104891 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Recharge Active Study Product 3
Description: Participants will use their Radicle Recharge Active Study Product 3 as directed for a period of 5 hours.
Study NCT05467605 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: probiotics( Lactobacillus acidophilus, lactobacillus delbruekii and lactobacillus fermentum 10 billions),
Description: therapeutic intervention, Children will be randomized into two groups using sealed envelopes on admission after meeting inclusion criteria, group ONE will receive multi strain probiotic product which contains(Lactobacillus acidophilus, lactobacillus delbruekii and lactobacillus fermentum 10 billions),
Study NCT05467605 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: maltose dissolved in distilled water
Description: the other group placebo (GROUP TWO ) will receive maltose dissolved in 10 ml distilled water .
Study NCT04976478 — intervention group
Intervention type: DRUG
Intervention: Nimotuzumab
Description: Patients receive Nimotuzumab: 200mg, intravenous infusion, weekly for 6 weeks.
Study NCT04976478 — intervention group
Intervention type: RADIATION
Intervention: EBRT combined with brachytherapy
Description: IMRT/VMAT are adopted. A total dose of 45-50.4 Gy, 1.8\~2.0Gy/f, 25\~ 28F in pelvic and/or extension filed. For patients with metastasis in pelvic lymph node and abdominal para-aortic lymph node, the dose of radiation in local lesion will be increased to 60\~66Gy. For patients at stage IIIB, concurrent radiation will be given in parametrial extension or in the late course the dose will be increased to 60Gy.~Brachytherapy: Three dimensional high dose rate brachytherapy is used with HR-CTV D90 cumulative dose of 80\~85Gy (EQD2); If the tumor diameter is ≥4cm, HR-CTV D90 cumulative dose is ≥87Gy (EQD2). Brachytherapy combined with external beam radiotherapy will be completed within 8 weeks.
Study NCT05486507 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Montmorency tart cherry
Description: US grown Montmorency tart cherry 60ml per day for 6 weeks.
Study NCT05486507 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taste matched placebo.
Study NCT05267743 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegoprazan 50mg QD
Description: Tegoprazan 50mg tablets will be orally administered, once daily, for up to 2 weeks or 4 weeks.
Study NCT05267743 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lansoprazole 30mg QD
Description: Lansoprazole 30mg tablets will be orally administered, once daily, for up to 2 weeks or 4 weeks.
Study NCT06324851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drospirenone / Estetrol
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Drospirenone/Estetrol at any time of the menstrual cycle
Study NCT06324851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nomegestrol Acetate / Estradiol
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol at any time of the menstrual cycle
Study NCT06324851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethinylestradiol / Dienogest
Description: Endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Ethinylestradiol/Dienogest at any time of the menstrual cycle
Study NCT06532136 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Deucravacitinib
Description: Deucravacitinib 6 mg orally once daily.
Study NCT06532136 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Matching placebo orally once daily.
Study NCT05977335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Autonomic Function Testing
Description: Autonomic Function Testing (AFT) includes Valsalva Manoever, Deep Breathing Test, and Head-up Tilt Table Testing.
Study NCT06134089 — intervention group
Intervention type: BEHAVIORAL
Intervention: Perceived Effectiveness Prompt
Description: Participants will assess pairs of messages with the prompt, Which of the messages below is more likely to make you want to get screened for colorectal cancer?~Participants will also be able to provide their own idea for a message rather than selecting a message from the pairs presented.
Study NCT06134089 — intervention group
Intervention type: BEHAVIORAL
Intervention: Perceived Shareability Prompt
Description: Participants will assess pairs of messages with the prompt, Which of the messages below would you be more likely to share with your friends or family?~Participants will also be able to provide their own idea for a message rather than selecting a message from the pairs presented.
Study NCT06419777 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin
Description: Insulin will be used in gestational diabetics to control blood glucose levels
Study NCT06119711 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT04565028 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency Management (CM)
Description: Contingency management is an intensive behavioral therapy in which participants are paid to reduce substance use.
Study NCT06373835 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emodepside
Description: 5 mg tablets of emodepside and matching placebo tablets, 3mg ivermectin
Study NCT06373835 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Emodepside
Description: 5 mg tablets of emodepside and matching placebo tablets, 3mg ivermectin
Study NCT06373835 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Emodepside
Description: 5 mg tablets of emodepside and matching placebo tablets, 3mg ivermectin
Study NCT05990452 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 9MW2921
Description: All subjects will receive 9MW2921 by intravenous (IV) every 3 weeks.
Study NCT05646004 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cataract surgery
Description: Implantation of 621 lens
Study NCT04986111 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Linear skin closure with wound drain
Description: An oval incision is made around the ileostomy and the continuity of the intestinal tract is restored after adhesion division.~Methods of anastomosis include either side-to-side or end-to-end, hand-sewing or stapling.~Linear suture of the rectus abdominis fascia layer by layer. A Jackson-Pratt drainage tube is placed in the subcutaneous tissue and vertical mattress suture is performed with a non-absorbable thread.
Study NCT04986111 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Purse-string skin closure with negative pressure wound therapy
Description: Recover the intestinal continuity after adhesion division by making a circular incision along the ileostomy Methods of anastomosis include either side-to-side or end-to-end, hand-sewing or stapling.~Linear suture of the rectus abdominis fascia layer by layer. Negative pressure wound therapy is performed after suturing the subcutaneous tissue using absorbable thread.
Study NCT05421546 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Spermidine or Placebo
Description: The supplement, Spermidine, is made mainly from wheatgerm and can be bought in health food shops. It is a powder that can be easily dissolved in water and taken as a drink. The 'placebo' is a sugar powder that can be similarly dissolved in water and taken as a drink.
Study NCT05421546 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Spermidine or Placebo
Description: The supplement, Spermidine, is made mainly from wheatgerm and can be bought in health food shops. It is a powder that can be easily dissolved in water and taken as a drink. The 'placebo' is a sugar powder that can be similarly dissolved in water and taken as a drink.
Study NCT05900258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirbanibulin
Description: Klisyri® 10 mg/g Ointment (Tirbanibulin) patients receive Tirbanibulin on sun-damaged areas of the face for five days, according to the SmPC.
Study NCT06444997 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxycodone Hydrochloride
Description: Oxycodone hydrochloride will be administered at a continuous infusion dose of 0.03-0.2 mg/kg/h.
Study NCT06444997 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil
Description: Remifentanil will be administered at a continuous infusion dose of 2-9 μg/kg/h.
Study NCT06322173 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: NGS Analysis
Description: An analytical pipeline with NGS technology developed in the GENRES study will be used for the identification of infecting microorganisms and the drug resistance they carry. For this purpose, a sequencing method will be identified and adopted that can obtain gene sequences of approximately 75 bp in length and on the Illumina MiSeq platform. Furthermore, IT software and bioinformatics analyzes with specific quality control parameters (pre- and post-alignment of reads) will be identified and adopted in order to develop an IVD system that includes a complete package of sequencing kits and software.
Study NCT05171985 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine sedation
Description: 72 cases sedated on Propofol infusion 50-200 mg/h + Fentanyl infusion 25-250 mcg/h guided by hemodynamics in addition to Dexmedetomidine infusion 0.2 - 1 mcg/kg/h, and also guided by hemodynamics.
Study NCT05171985 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Dexmedetomidine sedation
Description: 72 cases sedated on Propofol infusion 50-200 mg/h + Fentanyl infusion 25-250 mcg/h guided by hemodynamics in addition to Dexmedetomidine infusion 0.2 - 1 mcg/kg/h, and also guided by hemodynamics.
Study NCT06437639 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mexidol
Description: Neurocytoprotector
Study NCT06120049 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [18F]-MFBG PET CT
Description: \[18F\]-MFBG will be acquired at the Leuven University hospital on a GE MI4 PET/CT camera, with low dose CT and 120 MBq injected activity. Dynamic imaging between 0-60 minutes and 100-120 minutes (patients) and 0-70 minutes and 90-120 minutes (healthy volunteers).~Venous sampling between 5-120 minutes will be obtained through a second catheter, 6 venous samples will be taken.~In healthy up to 5 control subjects, full arterial sampling (0-120 minutes,) will also be done.~If patient comfort allows, after the dynamic cardiac scan 2 hours post-injection field dynamic scan, a fast late timepoint whole body PET/CT will be taken (2 min/bed position, 11 mAs low dose CT; estimated 10-12 minutes).
Study NCT06120049 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [18F]-FE-PE2I PET CT or PET MRI
Description: \[18F\]-FE-PE2I will be performed at the University Hospital Leuven with the GE Signa simultaneous PET/MR with acquisition at 50-70 minutes postinjection or at the University Hospital in Gent using a Siemens PET/CT, GE MI4 PET/CT.~Injected activity: 120 MBq
Study NCT04878276 — intervention group
Intervention type: DEVICE
Intervention: Dimet 5
Description: The application is carried out according to the enclosed instructions for use.
Study NCT06392178 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SugarVita
Description: Serious digital game (application) that can be played on mobile phone, tablet or personal computer. Self-developed game.
Study NCT05865756 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Acoustic cough features analysis
Description: Acoustic cough features analysis
Study NCT06287931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ursodoxycholic acid group
Description: Ursodoxycholic acid, 250mg po tid x 6 months
Study NCT06287931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bifidobacterium group
Description: Bifidobacteria, 210 mg po tid x 6 months
Study NCT04745247 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: RSS
Description: Repetitive somatosensory stimulation (RSS) applied on a small region of the face for 3 hours~Sham Repetitive somatosensory stimulation (RSS) applied on a small region of the face for 3 hours : the number of stimuli is reduced compared to the effective RSS
Study NCT04745247 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: RSS
Description: Repetitive somatosensory stimulation (RSS) applied on a small region of the face for 3 hours~Sham Repetitive somatosensory stimulation (RSS) applied on a small region of the face for 3 hours : the number of stimuli is reduced compared to the effective RSS
Study NCT05255627 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: Prevention, Care and Treatment of Pressure Injury was explained by 1 researcher who is responsible for the Nursing Fundamentals course, using written educational material prepared in line with the literature.
Study NCT05255627 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mobile application group (Experimental Group)
Description: A mobile application program was installed on the phones of the experimental group students for their benefit. Prevention, Care and Treatment of Pressure Injury was explained by 1 researcher who is responsible for the Nursing Fundamentals course, using a mobile application program prepared in line with the literature.
Study NCT06120049 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: [123I]-MIBG SPECT CT
Description: \[123I\]-MIBG SPECT/CT (low dose CT) will be performed at the local nuclear medicine department of each participating center.~Injected activity: 111 MBq
Study NCT05064540 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alto Abdominal Stent Graft System
Description: Endovascular Abdominal Aneurysm Repair (EVAR) using commercially available, FDA approved endovascular graft systems implanted.
Study NCT05064540 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FDA Approved EVAR AAA Graft Systems
Description: FDA approved comparator of choice