AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05221281 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal intervention consisting of four core components
Description: Core Component 1: Individualized Assessment: Each participant will undergo individualized assessment of their biopsychosocial risk profile (PIBD INTERMED), self-efficacy (IBD-SES-A), function (IBD-DI), transition readiness (TRAQ) and IBD knowledge (IBD-KID2), and depression, anxiety and activation.~Core Component 2: Transition Navigator: Participants will be assigned a transition navigators, who will have knowledge of IBD, an understanding of the care pathway involved in transitioning IBD patients, and the skills and ability to provide psychosocial support.~Core Component 3: Participant Skills-building: Skills-building materials delivered virtually. Navigators will also be trained as motivational coaches and will lead separate personalized virtual sessions targeting individual skills that have been identified as deficient during the assessment phase.~Core Component 4: eLearning Curriculum: Organized online eLearning modules with reinforcement of knowledge by the navigators.
Study NCT05733520 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brain CareNotes
Description: The Brain CareNotes mobile telehealth app is used by unpaid caregivers for BPSD management. It includes remote communication with an external human support person-a care coach-as well as features for users to independently perform health-related activities.
Study NCT05733520 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dementia Guide Expert
Description: Dementia Guide Expert provides education only and no interactive BPSD management support, coaching, assessment, or external response. It contains evidence-based expert information on what dementia is, types, contributing factors, risks, symptoms, stages, diagnosis, tests, treatment, management, communication techniques, and links to resources and support services.
Study NCT05221281 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Standard of care
Description: The control group will be provided a standardized version of routine care for transition. In addition to recruiting centers' standard of care, all participating centers will implement the following transition interventions:~1. A written letter explaining the goals of transition to the patient and family.~2. Completion of age-appropriate checklists to ensure adolescents are meeting milestones of transition (developed by the TRACC Network).51~3. Annual online live educational webinars on transition and adolescent issues (hosted by the CIDsCaNN Education Committee).~4. Completion of the Pediatric INTERMED,52 with appropriate biopsychosocial intervention.~5. Completion of a transfer-of-care summary letter sent to the receiving adult gastroenterologist using a standardized letter template.53~The Control Group may also receive any interventions currently in place in their participating care center, but will not receive the formal 4-component intervention described below.
Study NCT05183295 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NEAAR Medical Food
Description: Standardized non-essential amino acid restricted medical food
Study NCT06395376 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bikram Hot Yoga Intervention
Description: Active participants engage in a yoga intervention which entails participating in a minimum of 60-minutes of hot yoga (Bikram sequence), 3x per week in a heated room at 40 degrees C. The intervention will be 6-weeks of active intervention when they are participating in yoga, followed by an 6-week washout period where they will be asked to not practice yoga. Participants will be asked to give blood at 9 timepoints throughout the 12-week study, including baseline, week one, midpoint, end of Hot Yoga Intervention (Week 6) and after Washout (Week 12)
Study NCT06395376 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Hot Yoga Washout
Description: The Washout period consists of 6-weeks occurring immediately after the Hot Yoga Intervention during which the participants do not perform any hot yoga.
Study NCT06534528 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Human umbilical cord mesenchymal stem cell injection
Description: Different doses of human umbilical cord mesenchymal stem cell injection were infused to the focus of patients with idiopathic pulmonary fibrosis through bronchoscope, and the tolerance of subjects to different doses of human umbilical cord mesenchymal stem cell injection was observed, and the curative effect was preliminarily observed.
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: difelikefalin 0.25 mg
Description: Oral difelikefalin 0.25 mg tablets administered twice daily
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: difelikefalin 0.5 mg
Description: Oral difelikefalin 0.5 mg tablets administered twice daily
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCS Cream
Description: TCS cream applied by study subjects to skin lesions once a day until control is achieved, then as needed
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TCS Cream
Description: TCS cream applied by study subjects to skin lesions once a day until control is achieved, then as needed
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Oral Placebo tablets administered twice daily
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral Placebo tablets administered twice daily
Study NCT05387707 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: Vehicle Cream applied by study subjects to skin lesions once a day until control is achieved, then as needed
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Primary local anesthesia
Description: Tooth will be anaesthetized using Local anesthesia containing Articaine with epinephrine 1:100,000.
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Supplemental local anesthesia
Description: if needed
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Removal Of Caries and Access Cavity
Description: • Access cavity will be performed using a carbide round steel bur and tapered diamond stone until complete deroofing.
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rubber dam isolation of tooth
Description: Rubber dam isolation of tooth using certain clamps .
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bleeding control
Description: bleeding is controlled by using excavator for the removing the pulp tissue . using a piece of cotton soaked with Sodium hypochlorite. using local anesthesia with vasoconstrictor if needed and if suitable for the patient.
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Canal negotiation
Description: Coronal patency of the coronal and the Middle part of the canal using file #10 Apical patency of the apical part of the canal using #10
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coronal flaring
Description: Coronal flaring using Orifice opener of a certain Rotary system in and out motion first then brushing motion touching all the canal walls
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Working Length Determination (W.L)
Description: Working length determination (W.L) using #10 K File , working length is recorded using apex locator and confirmatory radiograph.
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Glide path
Description: Glide path of the canal Using #10 ,15 ,20 ,25 K files till becoming Super-Loose Inside the Canal at the recorded w.l to create a path for the rotary file .
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Irrigation
Description: Irrigation using 5.25% sodium hypochlorite introduced using side vented needle
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cleaning and shaping using rotary system
Description: Cleaning and shaping using rotary system plus irrigation and apical patency between every rotary file .
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Second w.l determination
Description: Second w.l determination using electronic apex locator before using final finishing rotary file .
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Apical gauging
Description: Establish the depth of apical constriction - this is the zero reading on your apex locator. your working length will be 0.5mm - 1mm short of this.~After cleaning and preparing the canal system to your working length, passively insert 02 taper hand files, starting from #15. If the file goes past the apical constriction (your working length + 0.5-1mm), then choose the next largest file and repeat.~When a file passively binds short of the apical constriction, that will be the upper limit of the apical constriction diameter. The smaller file before that would be the lower limit.~Apical gauging helps with:~Choosing the best master cone that closely matches canal length and taper Achieving true tug back - as opposed to false tug back! Minimising gutta percha extrusions during obturation
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Activation of the irrigant
Description: Activation of the irrigant using Manual Dynamic Agitation and Ultra x or eddy tips for activation
Study NCT06288425 — intervention group
Intervention type: OTHER
Intervention: Non interventional
Description: Non interventional. Review of clinical, biopsy (histopathological and molecular) features associated with rejection and non-rejection pathology diagnosis
Study NCT06252909 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interpersonal Psychotherapy for Couples
Description: Interpersonal Psychotherapy for Couples (IPT-C) consists of 8 weekly conjoint sessions. The clinical goals are to promote resolution of the role dispute via renegotiation of role relations between the marriage partners and improve common mental disorders in the woman. Like Interpersonal Psychotherapy, IPT-C has an initiation phase (Session 1-2), middle phase (Sessions 3-6), and termination phase (Sessions 7-8).
Study NCT06252909 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Interpersonal Psychotherapy (Individual)
Description: Interpersonal Psychotherapy (IPT) is an evidence-based treatment to reduce depression and other common mental disorders. It focuses on helping patients resolve interpersonal problems of disagreements, loneliness, life changes, and grief, and/or change their orientation to the problem.
Study NCT06391892 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neoadjuvant chemotherapy instead of upfront surgery
Description: All patients included into the study are recommended to go for upfront surgery (CT and CA19-9) by tumor board.~If preoperative ctDNA is positive, the investigators assume high risk for early recurrence (because of systemic tumor burden) and apply neoadjuvant chemotherapy at physicians choice instead.~* Apart from blood collection (within the scope of clinical routine), there is no additional diagnostic intervention performed on the patient.~* The respective neoadjuvant chemotherapeutical drug will be selected and applied by the treating medical oncologist at physicians choice (unaffected by study participation), usually mFOLFIRINOX or Gemcitabine/nabPaclitaxel at standardized dosage recommended by NCCN and local guidelines.~FOLFIRONOX: Folinic acid (also known as leucovorin), F - Fluorouracil (5-FU), IRIN - Irinotecan, OX - Oxaliplatin.
Study NCT06391892 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Upfront surgery
Description: Standard of care as recommended by tumor board (not affected by study conditions).
Study NCT04726891 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement-2-Music + Social Networking Support
Description: The primary goal of the proposed research is to conduct a 12-week pilot study of the SMART-HEALTH intervention in 30 individuals with SCI. There are several unique features of this study design, including a novel adapted exercise program (M2M), instructor-led, individualized training (M2M Live; described in D.2.1), individualized behavioral coaching, and social networking support.
Study NCT04782661 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-70075200
Description: JNJ-70075200 solution or solid formulations will be administered orally.
Study NCT04782661 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo solution will be administered orally.
Study NCT05214352 — intervention group
Intervention type: OTHER
Intervention: co-design in the intervention manual elaboration to increase the participation in the community
Description: It will co-design an intervention manual between all participants (families, young people with cerebral palsy and therapists) and researchers, using the involvement matrix to increase the participation of young people in the community.~Different focus grous will be created to work together and various online meetings, masterclass, workshops to increase the knowlodge in all groups.
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Master cone check
Description: Master cone check Clinically and confirmatory radiograph
Study NCT05841290 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: application of resin based sealer inside the canal in the resin based sealer group
Description: application done by inserting inside the canal by spreader or master cone
Study NCT05841290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: application of the sillicon based sealer inside the canal in the sillicon based group
Description: application done by injection inside the canal
Study NCT05841290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Obturation
Description: done by lateral condensation technique
Study NCT05841290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Visual Analogue Scale (VAS)
Description: Pain is evaluated using visual analogue scale (VAS) which is a pain rating scale. Scores are based on measures that are self-reported of symptoms that are recorded through a single handwritten mark placed at one point along the length of a 10-cm line representing a continuum between the two ends of the scale; on the left end of the scale (0 cm) means no pain and the on the right end of the scale (10 cm) worst pain
Study NCT05982730 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sensory-Augmented Postural Training
Description: To examine the safety and efficacy of postural training emphasized on the integration of multiple sensory information into motor control and to assess the effectiveness of postural training using Segway
Study NCT05215769 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Participate in a video intervention
Study NCT05215769 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study NCT05495984 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ERPs with electroencephalography (EEG)
Description: E-Prime 2.0 software will present visual and auditory stimuli in an experimental paradigm lasting approximately 30 minutes (ERPs). Visual stimuli will include photographs of color photographs of unfamiliar infants (aged 5- 10 months) balanced for ethnicity (Black/White) and gender (male/female) displaying happy neutral, and sad affective expressions. Auditory stimuli will include 2-second audio clips of high-distress and low-distress infant cries. Experimental procedure: Trials will consist of a central fixation cross (jittered 400-600ms), stimulus presentation (500ms faces, 2000ms cries), and blank screen (1000ms). Continuous electroencephalography (EEG) will be recorded using Net Station 4.2.1. A 128 Ag/Silver Chloride (AgCl) electrode net will be soaked in a warm potassium chloride solution, and net electrodes will be spaced evenly and symmetrically on each participant's head to cover the scalp.
Study NCT05495984 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MIO
Description: A 12-week, manualized, individual parenting psychotherapy developed specifically for mothers with addictions administered by the Principal Investigator. It is designed to foster a mother's capacity for mentalization or reflective functioning (RF). MIO is offered in conjunction with standard addiction treatment.
Study NCT05376852 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: based decitabine and olverembatinib（HQP1351)chemotherapy
Description: AP-CML treated with decitabine 10mg/m2 d1-5 intravenously (IV) over 60 minutes on days 1-5 and HQP1351 40mg qod every 28 days.After completion of HQP1351 lead-in, patients will receive HQP1351 PO qod on days 1-28 of subsequent cycles.~BC-CML:treated with decitabine 20mg/m2 d1-5 IV on days 1-5 and HQP1351 40mg qod every 28 days,with or without other chemotherapy Drugs
Study NCT05003063 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Donepzil
Description: Test
Study NCT06455722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-P15-041
Description: Intravenous injection of one dose of 111-148 MBq (3-4 mCi) \[68Ga\]Ga-P15-041. Tracer doses of \[68Ga\]Ga-P15-041 will be used to image lesions by PET/CT.
Study NCT05003063 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: Test
Study NCT05056610 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: food antigens on duodenal mucosa
Description: Administration of food antigens on duodenal mucosa and determining the response through confocal laser endomicroscopy
Study NCT04689763 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Training
Description: The programs contain sequential cognitive and exercise training, health lectures, and groups of daily living participation. We plan to assess the participants before and after the intervention programs. We expect that elders receiving training will improve on outcome measures. The results of the study will provide evidence of interventions for elderly with cognitive decline.
Study NCT05435339 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GEN1053
Description: GEN1053 will be administered as an intravenous (IV) infusion every 3rd week. The dose levels will be determined by the starting dose and the escalation steps taken in the trial.
Study NCT05240638 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TD Drainage
Description: Image-guided percutaneous cannulation of the TD and drainage with an endovascular catheter (microcatheter)
Study NCT04340492 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education to Adapted Physical Activity
Description: 4 group sessions (5 patients) aiming at promoting physical activity, the first three focusing respectively on endurance, posture and balance and power re-enforcement at one-week interval. A fourth session, 3 months latter is a consolidating session aiming at identify and overcome obstacles to practice physical activity in everyday life.
Study NCT04340492 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Standard care
Description: Standard care concerning Parkinson's disease and physical activity
Study NCT05647499 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Back 2 School program for problematic school absenteeism
Description: We will use the Danish version of the revised manual developed within the B2S study in Aarhus, Denmark. The B2S program consists of a 3 to 3,5 -hour initial clinical assessment, a clinical conference, 11 sessions where the youth and/or parent are attending, and a booster session after three months including youth and parent. The B2S manual comprise four school meetings with the child, parents, school staff and therapists present. In the Norwegian pilot study, we will add an extended school module to the B2S-program. The school module includes a pre-meeting interview with the schools in week 1 and session 1 with the school in week 2 or 3. The B2S counselor and the school will decide whether there is a need for an additional meeting between school meetings 1 and 2. There is also a booster session with the child, parents, the school and the B2S team 3 months after the program.
Study NCT06353815 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 4% articaine infiltration
Description: Two injections using short needle and dental syringe will be given , the first injection is 1.5 ml out of 1.8 ml of 4% articaine with 1:100,000 epinephrine (ARTINIBSA 4% 1:100,000) in the mucobuccal fold adjacent to the mandibular first Molar, the second injection is 0.3 ml in the lingual side for lingual soft and hard tissues .
Study NCT06353815 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 4% articaine infiltration
Description: Two injections using short needle and dental syringe will be given , the first injection is 1.5 ml out of 1.8 ml of 4% articaine with 1:100,000 epinephrine (ARTINIBSA 4% 1:100,000) in the mucobuccal fold adjacent to the mandibular first Molar, the second injection is 0.3 ml in the lingual side for lingual soft and hard tissues .
Study NCT06263595 — intervention group
Intervention type: DEVICE
Intervention: gastric antral sonography
Description: Participant will undergo gastric antrum ultrasound and be scanned in the supine position followed by the right lateral decubitus position. Qualitative and quantitative assessments will be completed.
Study NCT06012851 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Mobile behavioral parent training (mBPT)
Description: The mobile phone application includes behavioral parent training content (for example, praise, effective commands, reward systems) delivered in videos, examples, and quizzes that parents/caregivers access.
Study NCT06012851 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile behavioral parent training (mBPT)
Description: The mobile phone application includes behavioral parent training content (for example, praise, effective commands, reward systems) delivered in videos, examples, and quizzes that parents/caregivers access.