AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06223789 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Field Ablation
Description: Pulsed field ablation using the Volt PFA System
Study NCT04854889 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: Demethylating agents
Study NCT06607159 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Implementation of healthy habits teaching protocol
Description: Protocol for teaching healthy lifestyle habits, aimed at school-age children (initially between 1st and 4th grade of primary school), to be implemented transversally in schools. This protocol takes into account three levels of action: school, family and pupils. It includes materials in paper format and digital materials, that can be used both at school and at home.
Study NCT06607926 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thymosin Alpha 1
Description: 4.8 mg subcutaneous injection twice weekly over 12 weeks
Study NCT06607926 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tislelizumab
Description: 200mg, IV, d1 of each 21-d cycle, four cycles
Study NCT06607926 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: 200mg, IV, d1 of each 21-d cycle, four cycles
Study NCT06607926 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Platinum-doublet chemotherapy
Description: Chemotherapy regimen: (1) for squamous cell carcinoma: cisplatin/carboplatin + paclitaxel; and (2) for non-squamous cell carcinoma: cisplatin/carboplatin + pemetrexed.
Study NCT06607926 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Platinum-doublet chemotherapy
Description: Chemotherapy regimen: (1) for squamous cell carcinoma: cisplatin/carboplatin + paclitaxel; and (2) for non-squamous cell carcinoma: cisplatin/carboplatin + pemetrexed.
Study NCT06607055 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood collection
Description: HLA-DR dosage, at the time of inclusion and once a week then
Study NCT05468424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tablet (iPad or android) based role-playing game
Description: The intervention is a tablet (iPad or android) based role-playing game called FarmVille. In FarmVille the player assumes the role of a farmer tasked with tending to crops and farm animals and using what is produced to craft goods which can be sold to expand the farm. The participant is required to play FarmVille for 5 or more hours a week for 8 weeks.
Study NCT05468424 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: tablet (iPad or android) based word puzzles and image puzzles
Description: This intervention is a selection of tablet (iPad or android) word puzzles and image puzzles. One word puzzle involves word making (i.e., making words from a set of random letters), and the other word searching (i.e., finding words on a grid of letters). One image puzzle is Flow Free, a game that requires the player to connect pairs of same coloured dots positioned on a grid ranging from 5x5 to 9x9. The other image puzzle is a jigsaw. The participant is required to play these games for 5 or more hours a week for 8 weeks.
Study NCT04795596 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: secondary cytoreductive surgery
Description: resection of isolated recurrent ovarian carcinoma in platinum resistant disease
Study NCT04795596 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: second line chemotherapy according to investigator's choice
Study NCT04795596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: second line chemotherapy according to investigator's choice
Study NCT04819763 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical therapy
Description: Coordination training for lateral movement of the mandible (spatula exercise):~1. A wooden spatula is loosely placed between the teeth of the upper and lower jaw; the head must be aligned with the body axis; the exercise should be performed in front of a mirror.~2. The lower jaw moves to the left and back to the center with little contact to the spatula~3. The lower jaw moves to the right and back to the center under contact with the spatula~Training of the left lateral pterygoid muscle:~1. The left palm is placed on the left temple region~2. Right hand forms a fist and is placed on the tip of the right chin~3. Both arms are aligned parallel to the surface of the floor~4. The lower jaw is moved to the right against a moderate resistance of the fist = concentric muscle work~5. With measured force of the fist, the lower jaw is brought back to the center = eccentric muscle work (Right lateral pterygoid muscle training with opposite hands.)
Study NCT04819763 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Appliance therapy
Description: Upper and lower jaw impressions are registered by using an intraoral scanner. The arbitrary hinge axis position is determined using a face bow.~The stabilization appliance with anterior canine guidance is manufactured in the Lexmann laboratory in Dresden.~The stabilization appliance is incorporated by the dentist and the static and dynamic occlusion is checked. A tension-free fit of the appliance on the lower jaw is necessary. Additionally, equal contacts in the side teeth area and incisors guidance in the case of mandibular protrusion are checked visually and by using occlusion foil. During mandibular lateral movement only the canine guidance takes place and is also registered optically and by using occlusion foil.Interference contacts should be adjusted.~The patient is instructed to wear the stabilization appliance while sleeping. The wearing rhythm is described as intermittent. (three nights - wearing the appliance, one night - not wearing the appliance).
Study NCT04621019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BTL-785F
Description: Treatment with study device.
Study NCT05017597 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Exercises completed, and rate of perceived exertion (RPE) will be reviewed during \& after each exercise session. Exercises will be modified by either increasing or decreasing the intensity. Decisions will be made based RPE, physical symptoms \& any identified barriers or supports. Weeks 1, 3, 5, \& 7, Cancer-related fatigue (CRF) education will be assigned. During weeks 2, 4, 6, \& 8, CRF education will be reviewed and a plan for how to apply the information will be developed. Participant will be guided through 6 steps of problem solving to address one occupational performance problem identified by participant within Canadian Occupational Performance Measure. Goal \& action plan for the week will be shared with the participant electronically. At the beginning of each session, participant will describe progress on previous week action plan. Based on participant's response, either a new goal will be developed or the current one modified..
Study NCT05639075 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peripheral vision
Description: A gait analysis test will be performed in each patient after cataract surgery to test peripheral vision
Study NCT05833087 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Schema therapy
Description: 30 sessions of schema therapy. The therapy was developed by Jeffrey Young and others and encompasses elements from cognitive behavioral, psychodynamic, and gestalt therapies, as well as attachment theory.
Study NCT05833087 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Other psychotherapy
Description: In this arm, psychotherapy can be psychodynamic, cognitive behavioral, interpersonal or other evidence-based psychotherapies, aimed at changing cognitions, behavior, improve social relations and uncover unconstructive psychological patterns.
Study NCT05833087 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care package content
Description: The patient is offered prescription and monitoring of psychopharmacological treatment of up to 5 hours by a psychiatrist, when appropriate.~Additionally, patients have up to 3 hours of preparatory and diagnostic sessions and up to 4 hours of meetings with the participation of next-of-kin and/or collaboration partners in other public instances.
Study NCT05833087 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care package content
Description: The patient is offered prescription and monitoring of psychopharmacological treatment of up to 5 hours by a psychiatrist, when appropriate.~Additionally, patients have up to 3 hours of preparatory and diagnostic sessions and up to 4 hours of meetings with the participation of next-of-kin and/or collaboration partners in other public instances.
Study NCT05835908 — intervention group
Intervention type: OTHER
Intervention: Phone questionnaire
Description: Patients will be contacted by the investigator to collect information regarding follow-up from the initial call to the Emergency call center until the patient is taken care of in the health care facility to which he/she has been admitted.
Study NCT05093764 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: VIV TAVR with BVF using TCEP
Description: The insertion and retrieval of the SENTINEL device is performed at the time of the patients TAVR procedure in the same setting while they are sedated under moderate sedation or general anesthesia depending on the case. The device is inserted at the initiation of the procedure through 6F right radial artery access and the filters are positioned in the left common carotid artery and brachiocephalic artery. After deployment, the usual TAVR procedure is performed. At the conclusion of the procedure, the SENTINEL device is extracted and hemostasis is achieved at the radial access site in the usual fashion with patent hemostasis.
Study NCT06423092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music therapy songwriting
Description: Session 1: The goal of the first music therapy session is to know the parents musically and to provide information about song creation. This is achieved by exploring their favorite songs. Options for creating a song (original song or song parody) are presented and possibilities for creating lyrics are discussed.~Sessions 2-7: The structure of the song will be created and discussed with the parents. Parents will also be invited to include written messages from other family members in the lyrics if they wish. In each session, the developing welcome song is sung together with the parents, accompanied by the music therapist, who provides vocal or instrumental support.~The final sessions (Sessions 8-9) are dedicated to singing the final version of the song with the parents and their infant. Should the parents desire, a final recording of the song will also be made and the digital songbook will be created.
Study NCT04602546 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: BIS Complete Monitoring System
Description: The BIS™ EEG complete monitoring system is intended for use under the direct supervision of a licensed healthcare practitioner or by personnel trained in its proper use. The system and its associated parameters are intended for use on adult patients within a hospital or medical facility, providing patient care to monitor the state of the brain by data acquisition of EEG signals.
Study NCT04204538 — intervention group
Intervention type: OTHER
Intervention: Dietary habits
Description: Data collected using food frequency questionnaire
Study NCT04204538 — intervention group
Intervention type: OTHER
Intervention: Risk factors associated with metabolic syndrome
Description: Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome
Study NCT05097365 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin B12 + folic acid supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a vitamin B12 and folic acid supplementation, in addition to the usual therapy. The dietary supplementation will be by capsules, which will content 400 mcg of folic acid and 2000 mcg of vitamin B12 each.
Study NCT05097365 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplementation
Description: A 12 weeks parallel-group randomised controlled trial will be performed, in which erythematous lupus patients will complete a placebo supplementation.The placebo and vitamin B12 + folic acid supplement will be indistinguishable in terms of taste, smell, and appearance.
Study NCT04948892 — intervention group
Intervention type: OTHER
Intervention: Prescence of the father during cesarean section in general anesthesia
Description: The father is now present in the OR during cesarean section category 1, instead of waiting outside
Study NCT05566184 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Modified pacifier
Description: In the experimental group, a modified pacifier will be given to the child during the procedure, and the data will be collected. In the application of vascular access to children, a) before the procedure (20 minutes before), b) just before the procedure (20. minutes), c) during the procedure (between 20.-40. minutes), and d) 20 minutes after the procedure (40. minutes). Physiological variables that will be evaluated four times, once for each application, will be observed on the monitor, the FLACC Pain Assessment Scale will be recorded by the researcher and salivary cortisol level will be measured.
Study NCT04589663 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mometasone furoate
Description: Single inhaled dose of 100 µg mometasone furoate (MF) administered via Twisthaler® on Day 1
Study NCT04589663 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QMF149
Description: Single inhaled dose of QMF149 (75/40 µg indacaterol acetate/MF fixed dose combination) administered via Concept 1 device on Day 6-9
Study NCT04589663 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of Care (Soc)
Description: Asthma therapy: budesonide and salbutamol being the most frequently used (excluding MF and indacaterol acetate)
Study NCT06551376 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Ovarian Stimulation Start
Description: To compare ovarian response accordin to ovarian stimualtion start
Study NCT06551376 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ovarian Stimulation Start
Description: To compare ovarian response accordin to ovarian stimualtion start
Study NCT06006390 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA-targeted CAR-T cells
Description: Administration method: intravenous infusion； Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.
Study NCT06006390 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA-targeted CAR-T cells
Description: Administration method: intraperitoneal injection；Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.
Study NCT04792424 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Regional citrate anticoagulation
Description: Starting RCA 4 mmol/L (adjust the rate by BFR)
Study NCT04792424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Regional citrate anticoagulation
Description: Starting RCA 4 mmol/L (adjust the rate by BFR)
Study NCT04792424 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vasopressor
Description: Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine
Study NCT04792424 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vasopressor
Description: Vasopressors such as Norepinephrine, dopamine, milrinone, dobutamine
Study NCT04792424 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Antibiotic
Description: Antibacterial agents deemed appropriate by physicians in the ICU
Study NCT04792424 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotic
Description: Antibacterial agents deemed appropriate by physicians in the ICU
Study NCT04792424 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Dialysis with continuous renal replacement therapy
Description: Prismaflex
Study NCT04792424 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dialysis with continuous renal replacement therapy
Description: Prismaflex
Study NCT06410313 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ChampioNIR Ridaforolimus Eluting Peripheral Stent System
Description: ChampioNIR implantation in Patients with Superficial Femoral Artery Disease and/or Proximal Popliteal Artery disease
Study NCT04852471 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Post-Operative Counseling + FACT-G
Description: Counseling at discharge + FACT-G at enrollment, at 15-18 and at 30-32 days post-operative.
Study NCT04852471 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard Post-Operative Counseling + FACT-G
Description: Counseling at discharge + FACT-G at enrollment, at 15-18 and at 30-32 days post-operative.
Study NCT04852471 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PROM symptom tracker
Description: A 12-item symptom tracker adopted from the Patient Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (NCI-PRO-CTCAE), delivered via text, on days 4, 6, 8, 12, 18, 24, and 30 post surgery.
Study NCT04073472 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mesenchymal stem cells (MSCs)
Description: Allogeneic bone marrow derived mesenchymal stem cells (MSCs) direct injection to an ileal pouch fistula in the setting of Crohn's disease of the pouch
Study NCT04975191 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Resources
Description: Participants will be provided a list of resources available at VCU that are intended to support student success
Study NCT04975191 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Personalized Feedback Program (PFP)
Description: Participants will complete an interactive online program that explores their personality-related traits to provide personalized recommendations for success
Study NCT04975191 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Substance Use Feedback Program (BMI)
Description: Participants will complete an online program based on brief motivational intervention (BMI) content/principles that explores their current substance use patterns to make personalized recommendations for success
Study NCT05719792 — intervention group
Intervention type: PROCEDURE
Intervention: Transforaminal Epidural Steroid Injection
Description: In the TFESI group, all patients were positioned prone. The injection site was cleaned with povidone-iodine 3 times and a sterile drape was applied. Short-acting local anesthesia (3 mL of 2% prilocaine) was applied to the skin and subcutaneous tissue. A 3.5-inch, 22-gauge spinal needle was inserted just below the pedicle. It was advanced into the subpedicular space using the coaxial technique under the intermittent guidance of fluoroscopy. The needle position was confirmed through a lateral view. Using lateral views, the needle was placed at the posterior one-third of the foramen. Using the anteroposterior view, one to 2 mL of the contrast agent (300 mg/50 mL iohexol) was given and the distribution pattern was visualized. Once the epidural distribution of the contrast agent was confirmed without vascular flow, a mixture of 8 mg (two mL) of dexamethasone, 2 mL of physiological saline, and 1 mL (0.5%) of bupivacaine hydrochloride was injected.
Study NCT05719792 — intervention group
Intervention type: PROCEDURE
Intervention: Erector Spina Plane Block
Description: Patients are placed in the prone position to determine the vertebrae in the middle of the involved area. Following the provision of aseptic conditions, the spinous process of the vertebral midline is visualized using a high-frequency (8 MHz) linear ultrasound (USG) probe. The transverse process is, then, visualized approximately at the 3 cm lateral from the midline and the erector spinae muscle is visualized on it. The 22-gauge 50 mm block needle is advanced towards the in-plane section craniocaudally and the transverse process is touched. Then the needle is then withdrawn minimally to confirm that it is between the erector spinae muscle and the transverse process through hydrodissection. Following that, 5 mL from 0.5% bupivacaine hydrochloride, 8 mg dexamethasone and 3 ml saline is administered and local anesthetic spread is confirmed by USG.
Study NCT06501430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heating Therapy
Description: Heating Therapy will be performed on subjects along with PNF Exercises.
Study NCT06501430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Soft tissue Release
Description: Manual Soft tissue Release will be performed on subjects along with PNF Exercises.
Study NCT05199376 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cryotherapy
Description: The cryotherapy treatment lasts approximately 30 minutes during which two 10-minute freezing cycles are performed, separated by a reheating phase. During the freezing phases, the temperature is lowered below -40°C in the ablation zone, a temperature that is lethal for the cells.
Study NCT04848714 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ANAWIDOW [antivenin latrodectus (black widow) equine immune F(ab)2] lyophilized powder for solution 10 mL
Description: Antivenin latrodectus (black widow) equine immune F(ab)2\] lyophilized powder for solution 10 mL for intravenous use \[parenteral formulation\]; hence, a single-dose fasting pharmacokinetic study is planned.
Study NCT06012279 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin 10mg Tab
Description: Dapagliflozin is a drug that works through inhibition of sodium glucose transporter-2 resulting in glucosuria.
Study NCT05597644 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Trans-arterial uterine artery embolization
Description: transarterial angioembolization of uterine artery
Study NCT06037850 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Test orthokeratology lens
Description: Randomized to test orthokeratology lens worn during sleep every night
Study NCT06037850 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control orthokeratology lens
Description: Randomized to control orthokeratology lens worn during sleep every night