AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04623593 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ACDF
Description: Standard operative treatment for anterior cervical discectomy. Through a right or left-sided approach the disc space contents are resected. The endplates are prepared with curettes and the disc space contents are removed. The posterior longitudinal ligament is opened. The dura is visualized to ensure adequate decompression. A cage is implanted in the disc space. The disc removal and cage implantation can be performed at a single level or at multiple levels. The wound is closed in layers, after a prevertebral wound drain is placed.
Study NCT04623593 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ACDA
Description: The start of the procedure is the same as in the ACDF group. After the discectomy, a cervical disc prosthesis is placed in the disc space instead of a cage, in accordance with the manufacturer's protocol for implantation and endplate preparation. The disc removal and arthrodesis implantation can be performed at a single level or at multiple levels. Wound closure is similar to the ACDF procedure.
Study NCT03532958 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BNZ-1
Description: PEGylated peptide inhibitor of IL-2, IL-9, and IL-15
Study NCT05509660 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PUMA+
Description: Transdiagnostic CBT
Study NCT05509660 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: PUMA
Description: Transdiagnostic CBT
Study NCT03532958 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Dose volume consistent with weight-based dosing of BNZ-1
Study NCT06124924 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SGLT2 inhibitor
Description: a starting dose of a SGLT2i will be prescribed for the participant for pickup at discharge via the UMMC discharge pharmacy. The preferred prescription will be empagliflozin (Jardiance) 10mg daily with a 90-day fill and no refills, but this can be adjusted to other SGLT2i or other doses in the outpatient setting by either Dr. Murphy or by the participants' established providers, typically based on insurance company preferences among the three FDA-approved SGLT2i.
Study NCT05407636 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: ABBV-RGX-314 Dose 1
Description: AAV8 vector containing a transgene for anti-VEGF Fab (Dose 1)
Study NCT05407636 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: ABBV-RGX-314 Dose 2
Description: AAV8 vector containing a transgene for anti-VEGF Fab (Dose 2)
Study NCT05407636 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Aflibercept (EYLEA®)
Description: 2.0 mg (0.05 mL solution) administered by intravitreal injection approximately every 8 weeks after 3 monthly injections~Other Names:~• Eylea (anti-VEGF agent)
Study NCT05245175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sodium chloride particles
Description: Patients are exposed to sodium chloride particles alone for 4 hours in the Fraunhofer Allergen Challenge Chamber.
Study NCT05245175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactose particles
Description: Patients are exposed to lactose particles alone for 4 hours in the Fraunhofer Allergen Challenge Chamber.
Study NCT05245175 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Clean air
Description: Patients are exposed to clean air for 4 hours in the Fraunhofer Allergen Challenge Chamber.
Study NCT05245175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sodium chloride particles with house dust mite
Description: Patients are exposed to sodium chloride particles coupled with D. pteronyssinus for 4 hours in the Fraunhofer Allergen Challenge Chamber.
Study NCT05245175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lactose particles with house dust mite
Description: Patients are exposed to lactose particles coupled with D. pteronyssinus for 4 hours in the Fraunhofer Allergen Challenge Chamber.
Study NCT05381896 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Scoliosis Exercise Program
Description: Program will include breathing exercises, spinal stabilization and strengthening exercises, posture exercises and stretching execises.
Study NCT05381896 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Scoliosis Exercise Program
Description: Program will include breathing exercises, spinal stabilization and strengthening exercises, posture exercises and stretching execises.
Study NCT05381896 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Inspiratory Muscle Training
Description: Threshold IMT device will be used for the training. Training intensity will set at 30% of the maximum inspiratory pressure.
Study NCT05660642 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BPL-003
Description: Experimental BPL-003 arms: will investigate one of two doses of BPL-003 (Part 1) and two doses of BPL-003 (Part 2)
Study NCT04813120 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Uni-MVF condition and unimanual training mode using the new MT system (UM-UT)
Description: For the UM-UT group, the participants will be seated in front of the new MT system, and will be instructed to watch the real-time image reflection of movements of the non-affected arm and hand on the screen carefully. At the same time, the patients will need to imagine that the movements were performed by their affected arm and hand. In this group, only the non-affected arm and hand will need to perform the movements, but the affected one will not need to move.
Study NCT04813120 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Uni-MVF condition and bimanual training mode using the new MT system (UM-BT)
Description: During the UM-BT, as similar as the first group (UM-UT), the participants will be also seated in front of the new MT system, and be instructed to watch the real-time image reflection of the non-affected arm and hand's movements on the screen carefully and imagine that the movements were performed by the affected arm. However, in this UM-BT group, the bilateral training mode is emphasized, and thus both arms and hands will need to move. That is, during therapy, the patient's affected arm and hand will be required to move at his/her best motor ability with the non-affected arm and hand at the same time.
Study NCT04813120 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bi-MVF condition and bimanual training mode using the new MT system (BM-BT)
Description: For the BM-BT group, the participants will be seated in front of this new MT system, and be instructed to observe the real-time image reflection of the non-affected arm and hand's movements transformed and superimposed on both arms and hands (i.e., bi-MVF), and to imagine that the movements were performed by both arms and hands. In this group, bi-MVF and bilateral training mode are emphasized, and thus both arms and hands will also need to move. The patient's affected arm and hand will be required to move as could as possible simultaneously.
Study NCT04813120 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional MT using a mirror box
Description: During traditional MT, the participants will be seated in front of a mirror box placed at their mid-sagittal plane. The affected arm and hand of the participants will be placed inside the mirror box, and the non-affected arm and hand will be in front of the mirror. As similar to the UM-UT group, the participants will be instructed to watch the mirror reflection of the movements performed by the non-affected arm and hand carefully and to imagine that the movements were performed by the aﬀected arm and hand. In this group, the patient's affected arm and hand inside the mirror box will not need to move.
Study NCT06414031 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic Acid
Description: Intravenous administration
Study NCT06414031 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intravenous administration
Study NCT05652309 — intervention group
Intervention type: PROCEDURE
Intervention: spinal block and obturator nerve block
Description: spinal block and obturator nerve block
Study NCT06223074 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: IV Methylprednisolone administration
Description: Group 1 will receive 1g methylprednisolone IV for 3 or 5 days, according to the severity of the relapse
Study NCT06223074 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nasal Methylprednisolone (MT)
Description: Group 2 will receive the dose intranasal equivalent to 1g of methylprednisolone for 3 or 5 days according to the severity of the relapse
Study NCT05883683 — intervention group
Intervention type: OTHER
Intervention: Molecular Profiling & drug testing in tumor organoids and PDXs
Description: Molecular profiling of native tumor will be performed and analyzed by using a self-designed panel. Tumor organoids will be cultured from fresh tumor tissues and patient-derived xenografts model will be established using the tumor organoids. Drugs will be tested in the two models. And the recommendation will be communicated to the clinicians.
Study NCT05288478 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Dentoxol mouthrinse dosages
Description: Subjects will have a dose regimen assigned randomly, group A: first 6 weeks 5 times a day, following 6 weeks twice a day, and group B: first 6 weeks 2 times a day following 6 weeks 5 times a day, both with a 4 week washout period in between.
Study NCT06302478 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5E program
Description: Participants in the 5E program group will receive 7-day nursing interventions including~* Education: health education regarding venous thromboembolism prevention~* Elevation: leg elevation of 10-20 degrees~* Exercise: ankle exercises~* Enough fluid: adequate fluid uptake~* Early application of intermittent pneumatic compression (IPC): IPC use within 48 hours after admission
Study NCT05616221 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inactive Placebo administered via inhalation
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esketamine Nasal Product
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venlafaxine
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lithium
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lithium
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Valproate acid
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Valproate acid
Description: See arm description
Study NCT05603104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quetiapine
Description: See arm description
Study NCT05884255 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium (177Lu) Oxodotreotide Injection；long-acting Octreotide
Description: Lutetium (177Lu) Oxodotreotide Injection combined with standard-dose long-acting Octreotide
Study NCT05884255 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: long-acting Octreotide.
Description: High-dose long-acting Octreotide.
Study NCT05496673 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pastorex Latex Agglutination Test
Description: Rapid diagnosis of bacterial meningitis
Study NCT05496673 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Biofire PCR for meningitis
Description: Rapid diagnosis of multiple forms of meningitis
Study NCT05496673 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Immy CrAg Lateral Flow Assay
Description: Rapid diagnosis of cryptococcal meningitis
Study NCT04863157 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Survivor-SHIP
Description: Parent/guardian education about healthy sleep practices to improve their child's sleep health.
Study NCT05175027 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: hypochlorous acid
Description: Randomize
Study NCT05052658 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Neuraxial block placement
Description: The time and ease of administering neuraxial blocks in high BMI patients,for the management of labor and delivery pain, will be assessed.
Study NCT05052658 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Neuraxial block placement
Description: The time and ease of administering neuraxial blocks in high BMI patients,for the management of labor and delivery pain, will be assessed.
Study NCT05515107 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Videolaryngoscope size 1 Miller blade
Description: An intubating device that is used for endotracheal intubation. Endotracheal intubation will be performed by anesthesiologist with C-MAC videolaryngoscope
Study NCT05515107 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Videolaryngoscope size 1 Miller blade
Description: An intubating device that is used for endotracheal intubation. Endotracheal intubation will be performed by anesthesiologist with C-MAC videolaryngoscope
Study NCT05698498 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Guaranteed Income
Description: Guaranteed income payments will be disbursed monthly for a total of 24 months to participants who are randomized to the guaranteed income intervention group. Participants will be given the choice to select from one of two different payment strategies (equal monthly payments of $1,000/month vs hybrid payment schedule with initial amount of $6,500 the first month followed by $500/month x 11 months); payment strategy preferences will be re-assessed after 12 months. The choice of payment strategy will be strictly left to participants to specify.
Study NCT05698498 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Public Benefits Information Session
Description: All participants (both the control and intervention groups) will be offered the option of attending a Public Benefits Information Session during which they will receive a comprehensive resource directory of public benefit, assistance, and social service programs available to residents of Santa Clara County, have the opportunity to ask questions about enrolling in those programs, and also have the opportunity to seek additional benefits navigation assistance from our community partner, Sacred Heart Community Service. This session is intended to be optional, with the decision to attend and participant to be left to the discretion of each study participant. Attendance is not required for study participation.
Study NCT05698498 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Public Benefits Information Session
Description: All participants (both the control and intervention groups) will be offered the option of attending a Public Benefits Information Session during which they will receive a comprehensive resource directory of public benefit, assistance, and social service programs available to residents of Santa Clara County, have the opportunity to ask questions about enrolling in those programs, and also have the opportunity to seek additional benefits navigation assistance from our community partner, Sacred Heart Community Service. This session is intended to be optional, with the decision to attend and participant to be left to the discretion of each study participant. Attendance is not required for study participation.
Study NCT04316650 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Evaluation Scales
Description: * PATHOS / PEACCE : hypersexuality diagnostic scale~* PDQ-4+: Personality Diagnostic Questionnaire version 4~* AUDIT~* Life trajectory : THQ~* Cognitive function (MoCA, Stroop)~* ISDSS: and self report of sexual activity and desire~* BARS: Brief Adhesion Rating Scale (treatment observance)~* SF-36 scale : quality of life~* BDI-II : Beck Depression Inventory~* BSSI ; Beck suicidal Inventory~* Cognitive functioning evaluation : Molest and Rape Scale~* Empathy: EMPAT~* Evaluation of Cognitive functioning: denial evaluation and Mc Kibben minimization~* Baratt Impulsivity Scale~* CSBI~* Static 99 and Stable 2007
Study NCT04316650 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: osteodensitometry
Description: Osteodensitometry
Study NCT04316650 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: blood samples
Description: * Lipid profile (total cholesterol, triglycerides, HDL cholesterol)~* Liver function (ASAT, ALAT, total bilirubin, transferase gamma-glutamyl et alcalin phosphatases~* Kydney function~* Blood count~* Biological Measurements and Measurement of Systematic Plasma Testosterone and TeBG Levels in Sex Offenders check for pathology of the Gonadotropin Axis~* Biological Measurements of Plasma Prolactin level
Study NCT04316650 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: ECG
Description: ECG (heart rate, search for cardiac conduction disorders or cardiac arrhythmias)
Study NCT04316650 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Blood and saliva samples
Description: Blood and saliva samples
Study NCT04517500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Home-based pulmonary rehabilitation program
Description: Subjects will wear an activity monitor while doing at home exercises using a computer tablet
Study NCT04517500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based pulmonary rehabilitation program
Description: Subjects will wear an activity monitor while doing at home exercises using a computer tablet
Study NCT04517500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful breathing module
Description: Additional module on the computer tablet that involves inhaling and exhaling while following an animated ball on the computer screen.
Study NCT04517500 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health coaching
Description: Weekly coaching calls to discuss rehabilitation and health process using motivational interviewing
Study NCT04517500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health coaching
Description: Weekly coaching calls to discuss rehabilitation and health process using motivational interviewing
Study NCT05746052 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Punch insturment
Description: surgical and dermatological tool used mainly for skin biopsy and therapeutic skin disorders
Study NCT05541640 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline group
Description: normal saline infusion at the start of surgery
Study NCT05541640 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: lidocaine group
Description: lidocaine infusion at the start of surgery
Study NCT05909969 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvi-Fit app Training
Description: This group will receive Pelvic Floor Muscle Strengthening exercises through software application.
Study NCT05909969 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: This group will receive Pelvic Floor Muscle Strengthening exercises through instructions and pamphlets describing exercises.
Study NCT06501313 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Photobiomodulation
Description: Soft laser therapy
Study NCT06501313 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Photobiomodulation
Description: Soft laser therapy
Study NCT05497687 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance exercise
Description: The training schedule for supervised sessions (including community-based and home-based) will last for 60 minutes per session, two sessions per week. From Week 3 and 4, the exercise specialist will deliver supervised home-based training, with one in-person session via home visits and one session to be delivered remotely via an online platform (Zoom). Then the supervision will gradually tail off from Week 5 and onwards, from online supervised sessions, to unsupervised self-practice sessions. An in-person supervised home visit as a booster session will be given at Week 9, the beginning of the habituation phase. Telephone follow-ups will be arranged at Week 10 - 12 by the exercise specialist. All participants in the intervention group will be invited to take part in a qualitative interview to explore the feasibility and acceptability of the intervention.
Study NCT05007132 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Panitumumab 20 milligram/ML
Description: Participants receive Panitumumab at 6mg/ kg intravenously (IV) on Day 1 and 15 of each 28-day cycle. Treatment is continued until occurrence of progression according to RECIST 1.1 criteria as evaluated by the investigator or unacceptable toxicity.
Study NCT05007132 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Bevacizumab
Description: Participants receive bevacizumab at 5 mg/ kg intravenously (IV) on Day 1 and 15 of each 28-day cycle. Treatment is continued until occurrence of progression according to RECIST 1.1 criteria as evaluated by the investigator or unacceptable toxicity.
Study NCT05007132 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trifluridine/Tipiracil Hydrochloride
Description: Participants receive Trifluridine/tipiracil at 35 mg/m² BSA, twice daily, orally on days 1-5 and 8-12
Study NCT05007132 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Trifluridine/Tipiracil Hydrochloride
Description: Participants receive Trifluridine/tipiracil at 35 mg/m² BSA, twice daily, orally on days 1-5 and 8-12