AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01298882 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT05418413 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CTB
Description: conventional Twin-block (CTB) will be comprised of maxillary and mandibular removable appliances having the labial bows, adam's clasps, and with no incisal capping.
Study NCT05418413 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ETB
Description: will be comprised of maxillary and mandibular removable 1.5-mm biocryl sheet will be adapted separately on maxillary and mandibular casts with help of vacuum machine, and Acrylic bite blocks with the inclined plane will be fabricated on biocryl sheets sim
Study NCT05385237 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 4D-MRI
Description: Novel MR-imaging (MRI) and postprocessing techniques, making it possible to capture breathing-induced abdominal motion, including liver motion, under free-breathing. For the first time, these techniques - called 4D-MRI - were able to capture the abdominal organs with high spatial resolution in 3-dimensions at a high frame rate of 2-3 Hz and enabled an entirely new insight into the human body.
Study NCT05429593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide
Description: Tablet given orally
Study NCT05429593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin
Description: Tablet given orally
Study NCT05429593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Semaglutide/dapagliflozin
Description: Tablet given orally
Study NCT05698732 — intervention group
Intervention type: DEVICE
Intervention: Coroflex® ISAR NEO coronary stent system
Description: Patients in whom treatment with Coroflex® ISAR NEO coronary stent system has been attempted
Study NCT05038553 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT04641117 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Walking and Power Training
Study NCT05579132 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CN201
Description: The treatments include 2 cycles of induction treatment, 3 cycles of consolidation treatment, and up to 7 cycles of maintenance treatment. During the Treatment Period, subjects will receive CN201 by intravenous (IV) infusion once every week (QW), 4 weeks per treatment cycle. The subjects will receive 2 cycles of CN201 for induction. After induction treatment, the drug is discontinued for 2 weeks (treatment-free interval) before consolidation therapy is started, and each subsequent treatment cycle (4 weeks/treatment cycle) is followed by a 2-week treatment-free interval. Responders to induction treatment will continue to receive 3 cycles of consolidation treatment, followed by an additional up to 7 cycles of maintenance treatment, or until intolerable toxicity, disease progression, withdrawal of informed consent, loss to follow-up, receipt of other antitumor therapy, or death, whichever occurs first.
Study NCT05578508 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesenchymal Stem Cells (MSCs)
Description: Endoscopic injection of allogeneic bone marrow derived mesenchymal stem cells (MSCs) to the ileal pouch.
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Histamin-induced axon-reflex flare response
Description: Histamin-induced axon-reflex flare response
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Local heating-induced axon-reflex flare response
Description: Local heating-induced axon-reflex flare response
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 2-point discrimination tasks
Description: 2-point discrimination tasks
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: NC-Stat DPNCheck
Description: NC-Stat DPNCheck
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: QST
Description: QST
Study NCT05921097 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biothesiometry
Description: Biothesiometry
Study NCT06212089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TR-012001
Description: A single dose of TR-012001 will be administered.
Study NCT06212089 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Placebo
Description: A single dose of placebo will be administered.
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Right hemicolectomy
Description: Resection of the caecum and ascending colon is appropriate for patients with tumors located anywhere from caecum to the transverse colon
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Left hemicolectomy
Description: Resection of the sigmoid colon is appropriate for patients with tumors located anywhere from the distal transverse colon to the rectosigmoid junction.
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Sigmoid colon resection
Description: Resection of the sigmoid colon is appropriate for patients with tumors located in the sigmoid colon
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Anterior resection of the rectum
Description: AR is appropriate for tumors located in rectosigmoid junction and in the proximal rectum
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Low anterior resection of the rectum
Description: LAR is appropriate for tumors located in the middle and low rectum
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Abdominoperineal resection
Description: APR is appropriate for distal rectal cancers that invade the external sphincter or the levator muscles
Study NCT06050447 — intervention group
Intervention type: PROCEDURE
Intervention: Total Colectomy
Description: Total abdominal colectomy may be indicated for patients with primary multiple cancer tumors
Study NCT05167084 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metyrapone 250 mg Oral Tablets
Description: During one phase of the study: Metyrapone (pills of 250mg) on full stomach: Day 1 0-1-1, day 2 1-2-2, day 3 2-2-3 day 4 3-3-4 day 5 3-3-4 day 6 3-3-4 day 7 3-3-4 day 8 3-0-0
Study NCT05167084 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 250 mg Tablets
Description: During another phase of the study: identical looking placebo pills starting Day 1 0-1-1, day 2 1-2-2, day 3 2-2-3 day 4 3-3-4 day 5 3-3-4 day 6 3-3-4 day 7 3-3-4 day 8 3-0-0
Study NCT05167084 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrocortisone 19,9mg s.c., pulsatile with a flow rate of 10μl/s
Description: Hydrocortisone will be delivered subcutaneously via a pump in a pulsed fashion with a flow rate of 10μl/s from day 1 to day 8 in a total daily dose of 19.9mg
Study NCT05167084 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (0,9% NaCl solution)
Description: Placebo (0,9% NaCl solution) 19.9 mg/d subcutaneously via a pump in a pulsed fashion with a flow rate of 10μl/s from day 1 to day 8
Study NCT03543553 — intervention group
Intervention type: OTHER
Intervention: This is not an intervention study
Description: This is not an intervention study
Study NCT05472584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrophysiology assessment - corticospinal tract
Description: Kinematics and cortical spinal motor excitability
Study NCT05472584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrophysiology assessment - reticulospinal tract
Description: Kinematics and reticular spinal motor excitability
Study NCT05472584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrophysiology assessment - spinal motoneuron
Description: Kinematics and spinal motoneuron excitability
Study NCT05472584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity-based training
Description: Motor task
Study NCT05472584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous spinal cord stimulation
Description: Non-invasive spinal cord stimulation
Study NCT04896788 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Monitoring of the immune response
Description: Blood sample at 3,6,12,18 and 24 months in order to assess the blood level of anti-S1 / RBD anticoprs
Study NCT05592184 — intervention group
Intervention type: OTHER
Intervention: Exercise
Description: The experimental protocol begins with the assessment of self-perceived pain intensity and perceived exertion when using different intensities of elastic resistance, during wrist flexion and extension, at a controlled speed of 1.5sec/ phase. To assess the intensity at which they will work, participants will perform 2 repetitions and will be allowed a rest of 60s between sets until they obtain a score of 3 on the Borg CR10 scale. Exercises should be performed with the subject's available ROM. Participants are asked to move their body and trunk as little as possible and to perform the exercise smoothly, without stopping or accelerating. The exercise will be performed in a seated position, with the back supported by the backrest and the forearm resting on a table, with the shoulders and elbows bent at 90o, leaving the wrist free, with the elastic bands held under the feet (stepping on them).
Study NCT06231537 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Visual oral examination
Description: Oral preventive examinations in the three groups will be conducted over a one-year period. Individuals with oral injuries will be referred to stomatology, aligning with the existing protocol. Histopathological examinations of the biopsied lesions will be performed at the Oral Pathology Laboratory of the Faculty of Dentistry at the Federal University of Rio de Janeiro, following the established procedures.~Users diagnosed with malignancy will be directed to receive treatment at the reference hospital, with monitoring carried out by the Basic Health Unit responsible for coordinating care, in accordance with the current protocol.~In addition to histopathological examinations, the Faculty of Dentistry will be available to conduct a physical examination and biopsy if the user is not attended to by the Municipal Health Department. This additional resource ensures comprehensive care for individuals who may not have immediate access to municipal health services.
Study NCT05435560 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: During the imaging scan subjects will receive an initial bolus of dexmedetomidine over 10 minutes. After the bolus has been administered, a constant infusion of dexmedetomidine will be maintained for the remainder of the scan (about 60 minutes).
Study NCT05435560 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: During the imaging scan subjects will receive an initial bolus of saline over 10 minutes. After the bolus has been administered, a constant infusion of saline will be maintained for the remainder of the scan (about 60 minutes).
Study NCT05405699 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digitalized group psychoeducation
Description: Problem Solving Approach based problem solving skills psychoeducation's session topics of eight weeks are as follows:~1. Introduction and warm-up,~2. Problem orientation-identifying the problem,~3. Identifying prior problems-Which do I want to start from?~4. Recognizing the losses caused by problems and complaints,~5. Setting reachable and realistic goals,~6. Generating alternatives -What can I do?~7. Regulating emotions,~8. Experimenting and exploring. The main outcomes of each session were determined, and sessions were completed in approximately one hour as a semi-structured interactive group training according to group dynamics.~Three days a week for eight weeks, informative posts were shared, asynchronous testing and self-discovery activities were carried out, and a synchronous tele-psychoeducation session was held once a week. Participants were connected to the live broadcast of the research team and interacted via text messages.
Study NCT05479474 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet rich plasma
Description: Patients will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle.~* On the third month after the testicular PRP procedure, a TESE will be performed~* If the procedure is successful a new IVF cycle using the sperm procured from the procedure will be done.
Study NCT05258591 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Axem Home
Description: Rehabilitation system comprised of functional near-infrared spectroscopy headband (measuring from the motor cortex), as well as tablet-based software application (guiding stroke survivors through rehabilitation exercises for their hands/arms).
Study NCT05068947 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GV101
Description: GV101 administered once orally.
Study NCT05068947 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched placebo
Study NCT04214327 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Strengthening Families Program Online eLearning Game
Description: Families (parent/caregiver and children) are to play-test a highly interactive online gamified version of the Strengthening Families Program called SFP Online, with 10 lessons that utilize three 10-minute mini-sessions and games that teach parents evidence-based parenting and family relationship skills and teach youth social, life, and alcohol and drug refusal skills. Skills are reinforced through gaming. Game points are achieved by right answers to self-correcting mini-quizzes for low-stakes failure and through actual reported home practice of the skills. The SFP parenting skills have been shown to reduce risk factors and increase protective factors that prevent youth substance abuse.
Study NCT04214327 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SFP Home-use DVD
Description: Family views an 11-session SFP video series online or at home using a DVD that contains the same program and lesson content as the online condition; however, the lesson material is more static without the interaction required in the gamified version of SFP Online.
Study NCT04214327 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Wait-Listed Control
Description: Families receive no active intervention for 22 weeks; however, during this wait time, participants receive weekly email reminders that contain riddles and puzzles for youth and parents receive nutritional information and food preparation recipes. Following conclusion of the initial trial the wait-listed control sites are then administered the 10-session SFP Online intervention
Study NCT06378697 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK111
Description: Drug: AK111 subcutaneous injection at week 0,1, 4 and 4-weekly thereafter until week 48.
Study NCT06378697 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo+AK111
Description: Placebo+AK111 placebo subcutaneous injection at week 0,1, 4,8 and 12 follow AK111 4-weekly thereafter until week 48.
Study NCT05901155 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MedAL-mentor
Description: MedAL-mentor is a near real-time monitoring and benchmarking dashboard based on data collected through ePOCT+, providing direct feedback on several clinical indicators (antibiotic prescription, performance of key measurements, signs, and diagnostic tests).
Study NCT00959777 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DA-3031
Study NCT00959777 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Filgrastim
Study NCT05203705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 1, for 12 days
Study NCT05203705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 2, for 12 days
Study NCT05203705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 3, for 12 days
Study NCT05203705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2285 tablet
Description: SHR2285 tablet; dose 4, for 12 days
Study NCT05203705 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Enoxaparin
Description: Enoxaparin, for 12 days
Study NCT06544850 — intervention group
Intervention type: OTHER
Intervention: experimental group
Description: Oswestry Low Back Pain Questionnaire will be used to assess functional limitations in daily life activities of patients with low back pain. Recognize mobile application will be used to assess lateralization performance. Evaluation will be made with hand, foot and back modules of this application. Reaction time and accuracy given at the end of the application will be recorded. The most accurate response instruction will be given in the shortest possible time. Visual Analog Scale (VAS) will be used to measure general pain status of patients. Tampa Kinesiophobia Scale will be used to assess fear of movement. Pain catastrophizing level will be assessed with Pain Catastrophizing Scale. Two-point discrimination device will be used to assess two-point discrimination. Central Sensitization Inventory will be used for central sensitization findings.
Study NCT06544850 — intervention group
Intervention type: OTHER
Intervention: control group
Description: Healthy volunteer participants who meet the inclusion criteria will be evaluated with the tests applied to the experimental group
Study NCT04831047 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxymetazoline hydrochloride 0.1% ophthalmic solution
Description: One drop of Upneeq (Oxymetazoline hydrochloride 0.1% ophthalmic solution) will be applied to the ocular surface of each eye.
Study NCT04831047 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: One drop of placebo (balanced saline solution) will be applied to the ocular surface of each eye.
Study NCT05635175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hip abductors physiotherapy self training
Description: hip abductors self training program during 7 to 10 weeks associate with a PFMT
Study NCT05635175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard pelvic floor muscle training
Description: Standard pelvic floor muscle training
Study NCT05635175 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard pelvic floor muscle training
Description: Standard pelvic floor muscle training
Study NCT05635175 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard pelvic floor muscle training self training
Description: Standard pelvic floor muscle training self training
Study NCT04411186 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard Enhanced Recovery After Surgery (ERAS) Protocol
Description: Subjects receive standard MUSC ERAS protocol - fluid intake, hydration, anti-emetics, pain control, and several other considerations.
Study NCT04411186 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ERAS and 5 Lung Protective Interventions
Description: Subjects will receive the standard MUSC ERAS protocol - fluid intake, hydration, anti-emetics, pain control, and several other considerations. The subject will also receive the following lung protective interventions:~Pressure control ventilation-volume guaranteed (PCV-VG) ventilation at approximately 7cc/kg of predicted body weight (derived from combination of sex and height) Positive end-expiratory pressure (PEEP) 7cm H2O5 Immediately post intubation recruitment breath (30cm water for 30 seconds) Every 1 hour recruitment breath (30cm water for 30 seconds) 40% FIO2 initially - titrate up as necessary to maintain SPO2 >94%
Study NCT04669379 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EXPECT: Preoperative optimization of patient's expectations
Description: Patients work through an online-tool (around 30 minutes). This preoperative intervention aims to optimize patients' expectations by focusing on positive and realistic expectations regarding the surgery-benefits and recovery process, giving information, and giving advice for coping resources.
Study NCT05616377 — intervention group
Intervention type: OTHER
Intervention: Surgery or Radiotherapy
Description: Participants who underwent target therapy and surgery or radiotherapy were divided into target therapy + local therapy group. Participants who underwent target therapy alone were divided into target therapy alone group
Study NCT05616377 — intervention group
Intervention type: OTHER
Intervention: before or after target therapy
Description: Participants who underwent surgery or radiotherapy before target therapy were divided into local therapy before target therapy group. Participants who underwent surgery or radiotherapy after target therapy were divided into local therapy after target therapy group.
Study NCT06723899 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CanWork
Description: CanWork is an online, occupational therapy intervention to develop knowledge and skills to manage cancer-related symptoms that interfere with return to work. It consists of five, 90-minute group-based modules and an individual meeting between the occupational therapist facilitator and each participant. Each of the five-week group-based modules consists of two components: (i) education and peer-led discussion of cancer-related symptom management and supports available to manage difficulties in work and (ii) goal setting to facilitate application of knowledge and skills to work-related activities. Weekly topics include managing fatigue in work, understanding cancer-related cognitive impairments, strategies for managing physical and mental health in work and effective communication with employers and colleagues. The individual meeting between each participant and the occupational therapist is focused on designing a tailored return to work plan for each participant.
Study NCT06737796 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Finger Feeding
Description: feeding method
Study NCT05347017 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Alveolar ridge preservation using autogenous demineralized dentin block graft
Description: Atraumatic extraction of non restorable tooth, then the extracted tooth will be prepared and demineralized by HCL acid and inserted as demineralized dentin block graft in the socket