AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06039332 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Fitting of the audioprocessor with the auditory implant BCI602
Description: to compare the performance with BB system in two fitting-configurations (active comparator: DSL v5, experimental: DSL-BCD) using audiometric and subjective measures
Study NCT06381219 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Implementation of cow's milk in decreasingly heated forms
Description: Implementation of cow's milk in decreasingly heated forms to assess maintained remission of EoE
Study NCT06381219 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Implementation of hen's egg in decreasingly heated forms
Description: Implementation of hen's egg in decreasingly heated forms to assess maintained remission of EoE
Study NCT05774808 — intervention group
Intervention type: PROCEDURE
Intervention: Aortic valve replacement
Description: An aortic valve prosthesis is surgically implanted to treat AR
Study NCT05774808 — intervention group
Intervention type: PROCEDURE
Intervention: Mitral valve annuloplasty
Description: Surgical repair of the mitral valve in which a prosthetic ring is implanted to treat MR
Study NCT06532539 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel and Cisplatin
Description: Paclitaxel and Cisplatin Paclitaxel: 135 mg/m², intravenous infusion, Day 1, every 3 weeks (Q3W). Cisplatin: 75 mg/m², intravenous infusion, Days 1-3, every 3 weeks (Q3W). Duration: 6-8 cycles, until disease progression or intolerable adverse effects as judged by the investigator.~Alternative: If contraindicated for cisplatin, or if there is an allergy to paclitaxel and/or cisplatin, alternative drugs such as different types of paclitaxel or carboplatin can be used.
Study NCT06532539 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab
Description: Cadonilimab: 5-10 mg/kg, intravenous infusion, Day 1, every 3 weeks (Q3W). Duration: Continuous administration until disease progression, death, intolerable toxicity, subject's voluntary withdrawal, investigator's decision for withdrawal, or a maximum of 24 months.
Study NCT06532539 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Site Selection: Original site, lymph nodes, lung metastasis, bone metastasis, adrenal metastasis, brain metastasis, and other relatively isolated, well-vascularized lesions. Select at least one suitable lesion for radiotherapy based on the impact of the recurrent or metastatic lesion on the body, prioritizing lesions that cause symptoms, are life-threatening, or are expected to cause symptoms.All tumor lesions will be irradiated, which can be done in phases.~Dosage and Fractionation: Conventional or hypofractionated radiotherapy, with a biologically effective dose (BED) of ≥ 72 Gy. Dose adjustments can be made for brain metastases.~Timing: After completing relevant baseline examinations, radiotherapy can be implemented generally after 2-6 cycles of systemic therapy, or after the first cycle for small, solitary metastatic lesions.~echnique: IMRT, TOMO, SBRT, 3D-BT, interstitial implantation therapy, or proton therapy.
Study NCT05494879 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: microkinesitherapy treatment
Description: The therapeutic session of microkinesitherapy included a seeking of body scares both taking into account somatic dysfunctions as well as psychosomatic disorders. According to the creators of the method, Grosjean and Benini Everything that happens with us in a toxic level, either physically or emotionally, are stored by the brain which keeps memories and generates links that may harm the function of the cells generating a vast array of symptoms and dysfunctions.
Study NCT05522140 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature-based social intervention (NBIS)
Description: Nature-based social prescribing is a multicomponent, multi-level, behaviorally based complex intervention applaied by facilitators after a specific training. It comprises: a psychosocial component and nature-based activities. The psychosocial component is adapted from the group dynamic of Circle of Friends methodolgy focused on loneliness(Jansson A, Pitkälä KH, 2021) adapted to the cultural context of Prague and the target population (partitipants) of adults who lives in Prague. Participants start with an individual session and then meet once a week for two hours for 10 weeks.~At the first meeting together, participants select the nature-based activities they wish to conduct through a co-created menu.
Study NCT05522140 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care + menu with nature based activities
Description: Social prescribing as existing in usual care plus a written menu with the list of nature-based activities in the area.
Study NCT03939273 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin Oral
Description: 500 mg thrice per day for seven days
Study NCT03939273 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metronidazole Oral
Description: 500 mg thrice per day for seven days
Study NCT03939273 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ciprofloxacin Pill
Description: 500 mg twice per day for seven days
Study NCT03939273 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluconazole Oral Product
Description: 200 mg once per day for six days
Study NCT03939273 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebos
Description: seven day course of placebo tablets and capsules identical in appearance and number to active treatment
Study NCT06534073 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Socks
Description: Plantar orthotic elements will be designed, according to the participants' previous baropodometric pattern, to alleviate pathological plantar pressure. These elements will be integrated into commonly worn items by patients, such as stockings or socks.
Study NCT06534073 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Standard device
Description: Removable device of digital alignment to stabilize and unload the affected metatarsophalangeal joint. They do not require frequent replacement as they are washable and reusable elements.
Study NCT06534073 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Foot orthoses
Description: Custom-made foot orthoses.
Study NCT04750928 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Abemaciclib is to be administered orally on Days 1 through 28 of each 28-day cycle
Study NCT06147609 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: lower lingual holding arch space maintainer
Description: lower lingual holding arch space maintainer is an orthodontic device which connects two molars lower dental arch. it has an archwire, adapted to the lingual side of the lower anterior teeth, that soldered to the bands on first permanent molar
Study NCT06147609 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Removable partial denture space maintainer
Description: Removable Partial Denture consists of a pink or gum-colored plastic base to which the new, artificial, replacement teeth are attached to. a metal framework holds the denture in place inside the mouth
Study NCT04304846 — intervention group
Intervention type: OTHER
Intervention: Questionnaires and interviews
Description: List of questionnaires: ASQ, PSI, PPQ, SDQ, GSA and AMMI score obtained from mother during two separated interviews for the mother and the child at 3 and 5 years old
Study NCT05005676 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: acceleromyography
Description: Simultaneous measurement of the time course of a neuromuscular block with 2 acceleromyographs
Study NCT06567587 — intervention group
Intervention type: DRUG
Intervention: Dexmedetomidine
Description: Effect o dexmedetomine on agitated normal and psychotic patients on BIPAP who are suffer exaggerated COPD
Study NCT05663125 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laser interstitial thermal therapy
Description: Ablation of the tumor will be done by MRI-guided laser interstitial thermal therapy with the assistance of neuro-navigation.
Study NCT05663125 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide will be administered continuously from the 1st to the 21st day after LITT surgery. The oral dose of temozolomide is 75 mg/m2. And then, it will be given at a routine dose from the second month after surgery.
Study NCT04310202 — intervention group
Intervention type: OTHER
Intervention: Abbreviated Profile of Hearing Aid Benefit (APHAB)
Description: An intervention in this study which is outside the routine clinical practice of the clinics is the APHAB questionnaire that will be completed by the subjects on two occasions.
Study NCT04310202 — intervention group
Intervention type: OTHER
Intervention: Glasgow Benefit Inventory (GBI)
Description: An intervention in this study which is outside the routine clinical practice of the clinics is the GBI questionnaire that will be completed by the subjects on two occasions.
Study NCT04310202 — intervention group
Intervention type: OTHER
Intervention: Additional follow-up visits after surgery
Description: There are 1-2 additional follow-up visits after surgery (compared to the routine clinical practice of the surgeons/clinics).
Study NCT06567587 — intervention group
Intervention type: DEVICE
Intervention: BIPAP
Description: Put exaggerated COPD patients on non invasive ventillation
Study NCT05780944 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Paced Bottle-Feeding Education
Description: Participants will be asked to review an educational handout that outlines how to implement PBF during bottle-feeding interactions. Participants will then be asked to watch a video that further describes PBF and illustrates how to implement it with a live infant. A trained research assistant will then answer questions, further explain PBF, and demonstrate PBF with a baby doll, using a standardized script
Study NCT06521060 — intervention group
Intervention type: PROCEDURE
Intervention: tru cut biopsy
Description: Proving that preoperative TCB could provide accurate information about the histological nature of the tumor would have great impact for setting an adequate, tailored, oncologically safe treatment approach.
Study NCT06488586 — intervention group
Intervention type: DRUG
Intervention: Low dose IV Ketamine vs. IN Esketamine
Description: For IV ketamine treatment, ketamine is administered at 0.5mg/kg over 40 minutes. For IN esketamine treatment, esketamine is administered as a nasal spray, two sprays per nostril (56mg total) for the first treatment and three sprays per nostril (84mg) for the rest of the acute series. All treatments are administered at the academic center under the supervision of a mental health care professional. Patients are asked to come fasting at least two hours prior to treatment and to remain resting in the treatment room throughout the dosing session. Throughout each dosing session, blood pressure, oxygen levels, and onset, duration and severity of common side effects are recorded by nursing staff and/or physicians. Patients are discharged after a minimum of 30 minutes post administration, provided that the vital signs return to baseline and that the patient is calm, alert, and oriented.
Study NCT05669950 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu AG13909
Description: Solution for infusion
Study NCT06320340 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: the patients were performed following five exercises for 20 minutes of treatment session two days a week for the 8 weeks.: (1) the swan-dive vol. I, (2) the swan-dive vol II., (3) breast stroke preparation vol. I, (4) breast stroke preparation vol. II, and (5) swimming vol. II. All the exercises were repeated for the 10 times in a session. Before the exercises, patients were taught and instructed about the five key elements (lateral expansion, centralization, positioning the chest, the shoulder girdle, and the head) of clinical pilates that they should pay attention to while performing the exercises. In addition, verbal and tactile feedbacks were given to patients during all the treatment sessions to maintain the good posture and to perform exercises properly.
Study NCT06320340 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: the patients were performed following five exercises for 20 minutes of treatment session two days a week for the 8 weeks.: (1) the swan-dive vol. I, (2) the swan-dive vol II., (3) breast stroke preparation vol. I, (4) breast stroke preparation vol. II, and (5) swimming vol. II. All the exercises were repeated for the 10 times in a session. Before the exercises, patients were taught and instructed about the five key elements (lateral expansion, centralization, positioning the chest, the shoulder girdle, and the head) of clinical pilates that they should pay attention to while performing the exercises. In addition, verbal and tactile feedbacks were given to patients during all the treatment sessions to maintain the good posture and to perform exercises properly.
Study NCT06320340 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrotherapy
Description: Two channels of four-channelled Compex SP Fit-3 (MediCompex SA in Geneva, Switzerland) was used to apply NMES (120 mA, 400 μs, 150 Hz) on lower trapezius and serratus anterior muscles for 20 minutes during exercise.
Study NCT06458010 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YOLT-101
Description: The IP is administered intravenously at the predetermined dose.
Study NCT05515432 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Single oral dose of BAY3283142 IR (immediate release) tablet
Description: Single oral dose of BAY3283142 in participants with renal impairment compared to an age, gender and weight matched control group in an open-label study design
Study NCT05275023 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-73763989
Description: JNJ-73763989 will be administered subcutaneously.
Study NCT05275023 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1 inhibitor
Description: PD-1 inhibitor will be administered as IV infusion.
Study NCT05947149 — intervention group
Intervention type: OTHER
Intervention: questionnaires administration
Description: Enrolled people will be requested to fill in questionnaires. Cohort A affected by head and neck cancer: SF-12, EORTC QLQ-C30, EORTC QLQ-H\&N43, HADS, Brief COPE, BRCS.~Cohort A affected by skull base/brain cancer: SF-12, EORTC QLQ-BN20, HADS, Brief COPE, BRCS.~Cohort B will receive: EORTC QLQ-C30, BRCS, PROFFIT, SF-12, EORTC QLQ-H\&N43.
Study NCT06567938 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous coronary intervention
Description: PCI with DES implantation
Study NCT06567938 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous coronary intervention
Description: PCI with DES implantation
Study NCT06568926 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Serum Ferritin level
Description: follow up to the ferritin level in beta thalaseemia patients on oral chelation therapy
Study NCT05174078 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medically-tailored meals
Description: Medically tailored meals delivered to patients' homes for 15 weeks AND one medical nutrition therapy session with a dietician + viewership of 2 to 4 nutrition education videos.
Study NCT05174078 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Produce box and recipes
Description: Weekly produce box and access to recipes via internet for 15 weeks AND one medical nutrition therapy session with a dietician + viewership of 2 to 4 nutrition education videos.
Study NCT05112679 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PROPRIO FOOT® by Ossur
Description: Active prostheses like the PROPRIO FOOT® offer great potential to more completely restore the locomotor capabilities of individuals with transtibial amputation, perhaps enhancing RTD for military personnel. The investigators will examine factors of socket loading and direct measures of residual limb health so as to inform the optimization of prosthesis fit. The testing will consist of walking on a treadmill and the use of a 3D motion capture camera to track movement and angles of the participant's upper and lower extremities. Ascending and descending on stairs and ramps with the device will be completed. Participants will also have laser speckle imaging to measure blood flow to skin and transepidermal water loss measurement to check skin health.
Study NCT05112679 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Empower ankle by Ottobock
Description: Active prostheses -such as the Empower ankle offer great potential to more completely restore the locomotor capabilities of individuals with transtibial amputation, perhaps enhancing RTD for military personnel. The investigators will examine factors of socket loading and direct measures of residual limb health so as to inform the optimization of prosthesis fit. The testing will consist of walking on a treadmill and the use of a 3D motion capture camera to track movement and angles of the participant's upper and lower extremities. Ascending and descending on stairs and ramps with the device will be completed. Participants will also have laser speckle imaging to measure blood flow to skin and trans epidermal water loss measurement to check skin health.
Study NCT06358807 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthroscopic microfracture with intraoperative local PRP gel injection
Description: Arthroscopic microfracture:~An anteromedial portal and an anterolateral portal are routinely established. A diagnostic arthroscopy is performed. Defects of superficial cartilage, cystic components, and necrotic bone are debrided arthroscopically with curette and shaver to a stable circumferential rim. Microfracture awls are introduced and subchondral channels to 4-6 mm in depth are created, spacing the channels 3 to 5 mm apart across the entire surface of the lesion.~PRP preparation and local injection:~PRP is harvested using a PRP preparation kit via centrifugation. Fifty milliliters of autologous venous blood are drawn from the patient and processed. Platelet count is measured for quality control. On average 4 ml of (range 3-6) PRP is obtained and mixed with thrombin calcium agent in preparation for PRP gel. PRP gel is administered to the injured area using a blunt and long-tip injector, with direct visualization under arthroscope.
Study NCT06358807 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Isolated microfracture
Description: Arthroscopic microfracture:~An anteromedial portal and an anterolateral portal are routinely established. A diagnostic arthroscopy is performed. Defects of superficial cartilage, cystic components, and necrotic bone are debrided arthroscopically with curette and shaver to a stable circumferential rim. Microfracture awls are introduced and subchondral channels to 4-6 mm in depth are created, spacing the channels 3 to 5 mm apart across the entire surface of the lesion.
Study NCT05808894 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: extended pancreatic neck transection during laparoscopic pancreaticoduodenectomy
Description: Transect the pancreatic neck at ≥5mm and ≤10mm beyond the left side of the portal vein.
Study NCT05275023 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tenofovir Disoproxil
Description: Tenofovir disoproxil film-coated tablets will be administered orally.
Study NCT04701658 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bamlanivimab
Description: Administered intravenously.
Study NCT05783180 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sesderma LACTYFERRIN™ Forte and Sesderma ZINC Defense™
Description: Sesderma LACTYFERRIN™ Forte (64mg/20ml, TID) and Sesderma ZINC Defense™ (20mg/20ml QD)
Study NCT05783180 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Sesderma LACTYFERRIN™ Forte and Sesderma ZINC Defense™ (Placebo)
Study NCT05800522 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral parent or child directed intervention
Description: Control group will include different behavioral interventions that may include caretakers or the target child, and thus may vary in scope and intensity.
Study NCT05800522 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supportive Parents - Coping Kids
Description: Intervention group will receive the transdiagnostic parent intervention (SPARCK). SPARCK is designed to include up to 12 sessions with caretakers. If necessary and applicable, children can attend sessions. The starting point for the development of SPARCK has been the Social Interaction Learning model, which represents the behavioral management perspective. In addition, SPARCK consists of empirically supported components based on attachment theory, emotion socialization, CBT, and family accommodation. Thus, content and strategies have been collected from different theories to provide a diverse toolkit tailored to address transdiagnostic problems in families with externalizing, internalizing, and caregiver challenges. SPARCK content and target strategies are tailored to the needs of the families and children, and the manual explains the content and how the target strategies may be tailored and combined.
Study NCT05545722 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: life coaching group with diabetes
Description: Each patient was interviewed once a week. Coaching interviews were conducted one-on-one and in accordance with coaching principles.
Study NCT04846569 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Transition Theory-based Intervention
Description: The behavioral intervention is a theoretically driven curriculum focused on supporting mothers from pregnancy through postpartum in order to promote sustained HIV treatment adherence. Sessions utilize motivational interviewing and consist of a range of topics including motherhood, preparing for baby, disclosure, HIV education, adherence, birth experiences, support systems, and living positively.
Study NCT04846569 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Standard of Care Control
Description: In addition to standard of care, participants receive the first session of the Transition Theory-based Intervention curriculum which focuses on motherhood and preparation for baby but does not discuss the transition from pregnancy to postpartum or the postpartum period.