AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06480318 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENS
Description: The device is portable and battery-powered to preserve the patient functional activity. The device has two channels and the parameters of each channel can be adjusted independently of the other. The device contains a power supply, amplifier and electrodes to give a warning. The power supply and amplifier are located within the TENS device. Electrodes are connected to the device via cables. The current produced in the power supply is increased in the amplifier and reaches the electrodes. The device is self-gel to facilitate the transmission of current between the electrodes made of carbon silicon alloy and the skin surface. In the research, a dual-channel, four-electrode (5 cm x 5cm) TENS device will be used. TENS application will be applied every 12 hours, twice and for 20 minutes, 24 hours after the surgery.
Study NCT05538442 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Physiological recordings
Description: Physiological, cognitive, biological measurments
Study NCT05115682 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-intensity Intermittent Exercise
Description: The participants will perform a low-volume, High-intensity Intermittent Exercise bout on a cycle ergometer. Peak exercise capacity of the study participants will be determined on a separate occasion using a ramp-up maximal oxygen consumption test (VO2peak). A single exercise bout will consist of a 7-minute warm-up on a cycle ergometer, followed by 6 1-minute intervals of cycling at individual maximal capacity and 75rpm (rotations per minute). These intervals will be interspersed with 1-min breaks of cycling at low resistance and 75rpm, and the session will conclude with a 3-minute cool-down interval (20 minutes in total).
Study NCT04902547 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Education Workshop (PEWs)
Description: The comprehensive workshops will include a combination of didactic and interactive content on general pain and opioid education (1 hour workshop session to be co-presented by Drs Ryan Amadeo and Dana Turcotte) along with significant psychological content (co-presented by Drs Brigitte Sabourin and Gregg Tkachuk) making up the remainder of the day-long workshop. Content presented in PEWs will include opioid-related risks, identifying personal motivation for (or barriers to) tapering, goal setting, pain self-management, sleep hygiene and comprehensive focus on ACT and rethinking pain. During the interprofessionally co-facilitated sessions, participants will be provided with workbooks that will contain session specific content as well as take-home activities and information for their own personal use.
Study NCT04902547 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multidisciplinary Tapering Program
Description: The MTP will begin with a Baseline Tapering Visit and will include the same baseline health and well-being questionnaires, a medication review, relevant pain history, relevant opioid use history, discussion re: patient-specific tapering and functional goals, taper start date, and determination if a different opioid formulation will be required for the taper. A detailed taper plan will be prepared and reviewed by the study clinician(s) and provided to the patient. In general, tapers will begin with a 10% reduction of dose every 2 weeks until ⅓ of the original dose is met, or until taper goal has been met. If further tapering is planned once the patient reaches ⅓ of their original dose, the taper will be reduced to half the volume and rate noted above in order to improve tapering success.~Tapering plans and approaches may be changed (slowed, increased, halted etc.) based on follow up.
Study NCT06332677 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: the main genes and expression by comparing the transcriptomic lipidomic profile
Description: To identify the main genes and pathways differentially expressed and the main factors associ- ated in order to evaluate the role of SUV420H1/H2
Study NCT06230042 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Types of catheters
Description: One type of catheters were used for patients
Study NCT06230042 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Types of catheters
Description: One type of catheters were used for patients
Study NCT05514223 — intervention group
Intervention type: OTHER
Intervention: Biomaterial collection for observational purpose
Description: The semen will be collected to measure the free radical concentration in seminal plasma and sperm together with the diversity of microbiota. Both males with a normal semen analysis (SA) and abnormal SA according to the WHO guidelines (2010) will be included. Blood plasma will be collected to measure systemic radical concentration and all outcomes will be related to lifestyle factors and food intake acquired through hospital charts and routinely conducted questionnaires together with a food frequency Questionnaire (FFQ).
Study NCT05206201 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZY19489 Capsule
Description: Two part study with single and multiple dose
Study NCT05206201 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Capsule
Description: Two part study with single and multiple dose
Study NCT06623032 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medium-Chain Fatty Acid (MCFA)
Description: The participants will consume Medium-Chain Fatty Acid (MCFA) followed by Long-Chain Fatty Acid (LCFA)
Study NCT06623032 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Long-Chain Fatty Acid (LCFA)
Description: The participants will consume Long-Chain Fatty Acid (LCFA) followed by Medium-Chain Fatty Acid (MCFA).
Study NCT05962463 — intervention group
Intervention type: PROCEDURE
Intervention: Canal adductor blockade
Description: The same experienced anesthesiologist has performed all blocks. Always after surgical cleaning of the anteromedial thigh, all participants in this group received single shot ultrasound guided canal adductor blockade. After the blockade, all participants were monitored in our ambulance for the next hour.
Study NCT05962463 — intervention group
Intervention type: PROCEDURE
Intervention: Canal adductor pulsed radio-frequency therapy
Description: The same experienced anesthesiologist has performed all PRF therapy After surgical cleaning of the anteromedial thigh, all participants in this group received ultrasound-guided pulsed radiofrequency therapy. We've previously scanned the adductor canal and chose the middle of the canal as the entry point of the RF 10 cm needle with a 1 cm free tip. After sensory and motor checking all patients have gotten 6 minutes of therapy divided into 3 sequences of 2 minutes of 50 V current and 42ºC. After the treatment, all participants were monitored in our ambulance for the next hour.
Study NCT05282901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab 25 MG/1 ML Intravenous Solution
Description: Taken together, we hypothesize that combining pembrolizumab with lenvatinib in metastatic UM may target essential cellular oncogenic pathways while normalizing tumor vascularization, thus allowing an increased infiltration of the tumor by immune cells and an improved immune response.
Study NCT06629272 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: D-THIO (Deprescribing Thyroid Hormone In Older Adults)
Description: D-THIO consists of evidence-based pharmaceutical opinion letters to providers advising deprescribing for their patients 65 years and older with thyroid hormone overtreatment/misuse and EMPOWER (Eliminating Medications through Patient Ownership of End Results) brochures to their patients.
Study NCT06629272 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced usual care
Description: American Thyroid Association \[ATA\] provider guidelines, ATA patient brochure
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Escitalopram
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Paroxetine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Fluoxetine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Mirtazapine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Duloxetine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Sertraline
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Venlafaxine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Tianeptine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Vortioxetine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Desvenlafaxine
Description: Treatment for depression
Study NCT04446039 — intervention group
Intervention type: DRUG
Intervention: Bupropion
Description: Treatment for depression
Study NCT06724952 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: MTX S.C or IM and Silymarin 140 mg tab
Description: IM or S.C Methotrexate plus Silymarin tablets 140 mg once daily for 3 months.
Study NCT06724952 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: MTX S.C or IM
Description: IM or SC Methotrexate plus placebo tablet once daily for 3 months.
Study NCT06723002 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atherolive 500mg/day
Description: Patients will receive a study drug (olive leaf extracts) which will be prescribed at dose of 250 mg (one capsule ) twice daily ( total500mg daily) for one month.~patients will be assigned to one of three arm using a computer-generated randomization list ( 1:1:1 allocation ).
Study NCT06723002 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atherolive 1000/day
Description: Patients will receive a study drug (olive leaf extracts) which will be prescribed at dose of 500 mg (two capsule ) twice daily ( total 1000mg daily) for one month.~patients will be assigned to one of three arm using a computer-generated randomization list ( 1:1:1 allocation ).
Study NCT06723002 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placbo_Atherolive
Description: Patients will receive placebo which will be prescribed one capsule twice daily for one months.~patients will be assigned to one of three arm using a computer-generated randomization list ( 1:1:1 allocation ).
Study NCT06722287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Caregiver Mental Health Mobile Application Intervention
Description: The mobile application includes self-care tools, caregiving management tools, and online support groups
Study NCT06722339 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: low intensity transcranial focused ultrasound stimulation (TUS)
Description: Low-intensity transcranial focused ultrasound (TUS) provides an energy source with millimeter resolution that can be focused anywhere in the brain safely and effectively for non-invasive and transient neuromodulation. TUS is an important advance and of great significance for brain-mapping efforts, diagnostics, and therapies in neuroscience and particularly promising for addiction therapy as it provides unprecedented non-surgical access to the brain regardless of depth.~Low intensities of focused ultrasound (TUS) are used so that tissue damage does not occur, but neural activity can be modulated by mechanical effects.
Study NCT06724692 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ultra-processed breakfast
Description: With this intervention, participants will consume ultra-processed foods
Study NCT06724692 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low-processed breakfast
Description: With this intervention, participants will consume low-processed foods
Study NCT06723119 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resveratrol (VRES) 500 mg oral once daily.
Description: Resveratrol supplement will be provided in capsule form within a distinctly labeled bottle. Participants will be instructed to consume 2 capsules (500mg) of their assigned supplement with at least 8oz of water immediately upon waking for 17 days.
Study NCT06723119 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 500 mg oral once daily.
Description: Placebo will be supplement will be provided in capsule form within a distinctly labeled bottle. Participants will be instructed to consume 2 capsules (500mg) of their assigned supplement with at least 8oz of water immediately upon waking for 17 days.
Study NCT06722300 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasonic teeth cleaning plus Tinidazole microneedle patches applying
Description: After gargling with compound chlorhexidine rinse or 3% hydrogen peroxide rinse for 1 minute, ultrasonic teeth cleaning was performed. After teeth cleaning, the wound was rinsed with 3% hydrogen peroxide and bleeding was stopped. After ultrasonic teeth cleaning, two metronidazole oral composite microneedle patches were immediately applied to the upper and lower gums near the inner side of the first molar, especially where the teeth were lost or damaged. The mouth was kept closed for 15 minutes. After the microneedles were fully degraded, the patient could leave the clinic.
Study NCT04742114 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: use the face mask with Expiratory Positive Airway Pressure(EPAP).
Description: The subjects were divided into two groups. The first group use the face mask without EPAP, and the other group use the face mask with EPAP.
Study NCT04742114 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: use the face mask without Expiratory Positive Airway Pressure(EPAP).
Description: The subjects were divided into two groups. The first group use the face mask without EPAP, and the other group use the face mask with EPAP.
Study NCT04601805 — intervention group
Intervention type: DEVICE
Intervention: Observation
Description: We will record the vascular changes that follow the inflammatory bowel diseases
Study NCT06424886 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Landing error scoring system (LESS)
Description: Each group will perform two training blocks of 10 drop vertical jumping (DVJ) tasks. Knee joint position sense (KJPS), frontal plane projection angle (FPPA), and Landing Error Scoring System (LESS) assessments will be performed before and after the training blocks, and follow-up assessments will be performed 1 week later. The dominant limb of the participants (the side limb they use when kicking the ball) will be taken into account during the measurement.
Study NCT06241053 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal therapy with McConnell taping
Description: Multimodal therapy includes core exercises, hip exercises and vastus medialis training.~Core exercises include curls ups, toa taps, side planks, supine straight leg raising, side lying straight leg raising, prone knee flexion, draw foot circles in supine and side lying, prone cobra, hip and knee extension, weight bearing, hip flexion sitting on ball, wight bearing forward and backward on the ball, stairs up on Swiss ball. Hip training includes Hip abduction, Hip external rotation in standing and sitting. VMO muscle strengthening will includes squats with a ball.
Study NCT06241053 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multimodal therapy without McConnell taping
Description: Multimodal therapy without McConnell taping
Study NCT04840212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lavender-Sandalwood scented aromatherapy sticker
Description: The Lavender-Sandalwood scented aromatherapy sticker will be placed on the patient gown.
Study NCT06212102 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progestin primed ovarian stimulation
Description: HMG ( 300IU) was used during the follicular phase of ovarian stimulation (FPS) and during the luteal phase of ovarian stimulation (LPS). Progestin (dydrogesterone) 30 mg/day was used to prevent premature LH surge during the FPS and LPS.
Study NCT06212102 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: GnRH antagonist
Description: HMG ( 300IU) was used during the follicular phase of ovarian stimulation (FPS) and during the luteal phase of ovarian stimulation (LPS). Flexible GnRH antagonist protocol (Cetrorelix acetate) (0.2 mg) was used to prevent premature LH surge during the FPS and LPS.
Study NCT05595629 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: App-based remote blood pressure monitoring
Description: Fully synched bluetooth-enabled remote blood pressure monitoring using a smartphone application. The digital health company, Twistle, has modified an existing postpartum hypertension pathway in their app according to our hospital's management algorithm.
Study NCT05595629 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: text-message based remote blood pressure monitoring
Description: Participants will receive automatic blood pressure cuffs and instructions as to how to upload their measurements to the Electronic Medical Record.
Study NCT05863741 — intervention group
Intervention type: DEVICE
Intervention: Implantation of GMK Sphere with conventional instrumentation
Description: Implantation of GMK Sphere with conventional instrumentation (control group)
Study NCT05863741 — intervention group
Intervention type: DEVICE
Intervention: Implantation of GMK Sphere using the NextAR guidance system
Description: Implantation of GMK Sphere using the NextAR guidance system (NextAR group)
Study NCT05901727 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: Observational data collection only.
Study NCT06387420 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK117
Description: Subjects receive AK117 intravenously.
Study NCT05279950 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Full-mouth ultrasonic debridement with piezoelectric device (EMS, mini piezon)
Description: the use of ultrasonic oscillating tips allows supragingival and subgingival biofilm and dental calculus removal
Study NCT05279950 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Full-mouth ultrasonic debridement with magnetostrictive device (Cavitron Select, Dentsply)
Description: the use of ultrasonic oscillating tips allows supragingival and subgingival biofilm and dental calculus removal
Study NCT06383260 — intervention group
Intervention type: BEHAVIORAL
Intervention: Behavioral diagnostic
Description: Diagnosing the behavioral pattern
Study NCT05695274 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive muscle relaxation exercise
Description: Experimental group Fibromyalgia patients will be provided with progressive relaxation exercises twice a week. Progressive relaxation technique includes stretching and relaxing the bigmuscle groups (hands, arms, neck, shoulders, face, chest, abdomen,hip, feet andfingers) in the human body on purpose. When steps ofProgressive Relaxation Exercises are analyzed, it is observed thatlearning how to take correct and deep breaths is the most impor-tant step towards learning relaxation.
Study NCT06387420 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Subjects receive azacitidine subcutaneously.
Study NCT06387420 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Azacitidine
Description: Subjects receive azacitidine subcutaneously.
Study NCT06387420 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Subjects receive venetoclax orally.
Study NCT06387420 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Venetoclax
Description: Subjects receive venetoclax orally.
Study NCT06387420 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects receive placebo intravenously.
Study NCT04688229 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hummingbird hand training device plus standard of care rehabilitation
Description: The Hummingbird is a comprehensive hardware and software platform that isolates the hand, wrist, and forearm in a neutral and comfortable position, allowing linear force and angular torque to be measured at the finger-tips between 0-10 Newtons at milli-newton resolution at 100 Hz per digit, in 5 degrees of freedom simultaneously, in real-time, for all 5 digits. The platform allows isolating and characterizing fine resolution forces with sufficient sensitivity and resolution to record data in severe paralysis. The platform also comprises therapeutic software to train exploratory, individuated, and inter-digit complex finger movements by coupling force and torque output to NeuroAnimation physics-based virtual interface in engaging therapeutic experiences.
Study NCT04688229 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Comparison (sham) intervention
Description: During each hour of sham therapy the therapist will select cognitive tasks (e.g. puzzles and games) targeted to a level of difficulty based on the subjects ability. No grasping or object manipulation using the target upper limb will be included in this intervention. Rather, the participant will use either the unaffected limb (or non-targeted limb for SCI subjects) as needed for any particular puzzle or game.
Study NCT05513053 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH
Description: Pharmaceutical form: Solution for injection Route of administration: intramuscular
Study NCT05972681 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: 10 milliliters (ml) of bupivacaine 0.50% injected to the vaginal laceration site.
Study NCT05972681 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epinephrine
Description: Epinephrine (1:200,000) injected to the vaginal laceration site.
Study NCT05972681 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham normal saline arm
Description: 10 milliliter (ml) of normal saline injected to the vaginal laceration site.