AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04887090 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Routine perioperative management
Description: Comprehensive evaluation of cardiopulmonary function, preparation of respiratory tract, active treatment of coexisting diseases before operation, correction of water and electrolyte disorders and hypoproteinemia before operation. To prevent cross-infection during the operation, the intraoperative blood volume should be supplemented within the tolerance of cardiac function, the tissue perfusion should be sufficient, and the infusion should be uniform. Strengthen respiratory care after operation, prevent cardiovascular complications, pay attention to the speed and amount of blood transfusion, encourage early activities, promote lung expansion and prevent thrombophlebitis.
Study NCT05036057 — intervention group
Intervention type: OTHER
Intervention: Questionnaire
Description: Patients will do the Individual Knowledge Statement Questionnaire of Chronic Obstructive Pulmonary Disease (COPD), the COPD Assesment Test (CAT), the Saint George Respiratory Disease Questionnaire (SGRQ), the Charlson Comorbidity Index, and will rate the disease and general knowledge level on a numerical scale.~Proxies of patients will do the Individual Knowledge Statement Questionnaire of Chronic Obstructive Pulmonary Disease (COPD) and will rate the disease and general knowledge level on a numerical scale.
Study NCT04934189 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Empowerment Self Defense Training
Description: We have contracted with Prepare, Inc., the New York City chapter of IMPACT International to deliver the tailored ESD violence prevention intervention. IMPACT is an international ESD violence prevention organization with chapters across the United States. Prepare, Inc. will provide facilitators who have completed IMPACT's nationally standardized ESD violence prevention program requirements that include receipt of over 100 hours of training. IMPACT training is open to trans and cisgender women. The extensive training of IMPACT facilitators promotes intervention efficacy, while the risk of potential bias conferred by their experience with a pre-existing curriculum is mitigated by our community-engaged approach (i.e.,TW community members, service providers, and scientists \[PI and Co-I\] collectively shape the content of the final tailored ESD intervention, and TW co-facilitators will be present in every training session).
Study NCT05390151 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laser treatment of anal fistula
Description: using a radial laserprobe to treat transsphincteric fistula
Study NCT05390151 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: RAF
Description: current golden standard in transsphincteric fistula surgery
Study NCT05044936 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol Oil
Description: The dose that will be used for each administration of CBD will be 0.5mg/kg of body mass. As there are no recommendations for CBD from the FDA or through previous research in humans, and especially for CBD cream, the dosage is based on the United Kingdom's governing body recommending maximal amounts of CBD ingestion being 1 mg/kg per day. Further, the practical amount that companies recommend is anywhere from a pea size to a handful, which can range from high and low amounts. Using 0.5mg/kg of body mass allows for a moderate use of the lotion, as well as leaving extra quantities throughout the day should people want to use CBD outside of their post-workout recovery strategies outside of a laboratory setting. To convert the amount of CBD to the amount of lotion, we will divide the amount of CBD (0.5 mg/kg) by 4.85 (the amount of mg of CBD per gram of lotion). This will calculate the amount (in grams) of lotion each participant will receive.
Study NCT05044936 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise
Description: Participants will complete eccentric-based leg press (4-s lowering phase and 1-s upward phase) for 10 sets of 8 repetitions at 70% 1RM in order to induce muscle damage using a leg press machine. Three minutes of rest will be permitted between sets. Following the 10th leg press, participants will complete 4 sets of 20 consecutive plyometric lunges using only their body weight. Two minutes of rest will be permitted between sets. The muscle damaging protocol will be done upon completion of the 4th set of plyometric lunges.
Study NCT05855902 — intervention group
Intervention type: BEHAVIORAL
Intervention: group art therapy
Description: Art therapy will be offered in a weekly 1.5 hour group. Clients are provided a prompt and then asked to express their feelings using art, such as drawing/painting/etc.
Study NCT01435434 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: the Sepax is a tool to standardize adult stem cell. Ignite ®ICS injectable scaffold manufactured by Wright Medical Technology.
Study NCT05332977 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CAD-CAM fabricated provisional prosthesis
Description: Insertion of CAD-CAM fabricated provisional prosthesis (CAD-CAM) on axially placed or titled implants for rehabilitation of atrophic maxilla
Study NCT05332977 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DC (denture conversion) provisional prosthesis
Description: Insertion of denture conversion (DC) provisional prosthesis on axially placed or titled implants for rehabilitation of atrophic maxilla
Study NCT05907460 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transesophageal echocardiography examination during cardiopulmonary resuscitation
Description: Perform transesophageal echocardiography in patients with out-of-hospital cardiac arrest during cardiopulmonary resuscitation and adjust the chest compression site to compress the left ventricle and avoid left ventricular outflow tract.
Study NCT06502964 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALTO-101
Description: 4.5 mg ALTO-101 patches
Study NCT06502964 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ALTO-101 Transdermal Delivery System
Description: 4.5 mg ALTO-101 transdermal delivery system
Study NCT06502964 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Inactive placebo patches
Study NCT06502964 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Transdermal Delivery System
Description: Placebo transdermal delivery system
Study NCT04868604 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 64Cu-SAR-bisPSMA
Description: 64Cu-SAR-bisPSMA
Study NCT04868604 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 67Cu-SAR-bisPSMA
Description: 67Cu-SAR-bisPSMA
Study NCT05104567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THOR-707
Description: Solution for infusion: intravenous infusion
Study NCT05104567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Solution for infusion: intravenous infusion
Study NCT05104567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Solution for infusion: intravenous infusion
Study NCT04652908 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix
Description: As in the current standard fetal surgery, under sonographic guidance, initial uterine entry will be accomplished by uterine stapling device or similar. The fetus will be given an intramuscular injection of pain medications and paralytic. The myelomeningocele will be closed in a standardized manner under magnification. As in the standard fetal operation, the spinal cord will be dissected from surrounding tissue and allowed to drop into the spinal canal. The PMSC-ECM product will then be tailored to the size of the spinal cord and applied topically, cell side down. The PMSC-ECM product will be sutured in place to the dura. Finally, the fetal skin will be closed in the standard fashion. The amniotic fluid volume will be replaced and antibiotics will be added. The uterus will be closed. The abdominal fascial layer and skin will be closed in routine fashion.
Study NCT04652908 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Untreated contemporaneous cohort
Description: The addition of a non-PMSC treated cohort, the untreated contemporaneous cohort, has been added at the request of the FDA to provide contemporaneous patients for validation of the continued relevance of use of the outcomes of the MOMS trial as the comparison arm for the Phase 2a portion of the study.
Study NCT05026905 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Gemcitabine 1000 mg
Description: Gemcitabine 800mg/m2 in N/S 250ml over 30 minutes (or fixed dose rate 10 mg/m2/min) IV infusion on day 1 repeated every 14 days.
Study NCT05026905 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Nab paclitaxel
Description: Nab-paclitaxel 125mg/m2 over 30 minutes IV infusion on day 1 repeated every 14 days, followed by Gemcitabine
Study NCT05026905 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: S1
Description: S-1 orally 60-100 mg/day day 1 to 7 on in a 2-week cycle. The dose of S-1 is defined as follows:~* BSA \< 1.25 m2: 60 mg/day~* 1.25 m2 ≤ BSA \< 1.5 m2: 80 mg/day~* BSA ≥ 1.5 m2: 100 mg/day
Study NCT05026905 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: leucovorin
Description: leucovorin 30mg BID day 1 to 7 on in a 2-week cycle
Study NCT05026905 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Oxaliplatin
Description: Oxaliplatin 75mg/m2 in 250 mL of D5W over 120 minutes IV infusion on day 1 repeated every 14 days
Study NCT06426472 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web-based support program
Description: Web-based support program for infertile women with failed IVF experience
Study NCT05703880 — intervention group
Intervention type: DRUG
Intervention: Finerenone (Kerendia, BAY948862)
Description: Retrospective cohort analysis using United States Optum EHR data and OM1 RWDC databases.
Study NCT06653608 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nano-reinforced calcium hydroxide medicament
Description: Group A (Calcium hydroxide intracanal medicament reinforced with jasminum derived- titania nanoparticles)
Study NCT06653608 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium hydroxide without nanoparicles
Description: Group B ( Calcium hydroxide medicament without nanoparticles)
Study NCT05697029 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Tetrandrine
Description: tetrandrine TID for 28 days
Study NCT05697029 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tetrandrine
Description: tetrandrine TID for 28 days
Study NCT05016141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digital fall prevention program
Description: The participants will receive a digital fall prevention program consisting of fall risk reduction education (modified Matter of Balance), Otago Exercise Program, Personalized S.M.A.R.T Goals, and will use the app to keep track of their health and health events, including falls.
Study NCT06665295 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: THRIVE-CAR-T
Description: The intervention will begin several weeks prior to CAR-T cell therapy and will continue up until 30 days post CAR-T cell therapy. THRIVE-CAR-T is an educational and interactive digital application on an iPad for patients as they navigate receiving CAR-T. THRIVE-CAR-T is self-administered and provides education about the CAR-T cell therapy process, with several features to promote coping skills training informed by various well-established supportive psychotherapy strategies (e.g., cognitive behavior therapy, mindfulness, positive psychology), engagement, and health behavior change including gamification strategies, videos of patients who received CAR-T, and optional content.
Study NCT06668675 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A serious game known as the 'Happy Heart' will be used as the intervention.
Description: The serious game known as 'Happy Heart' is a mobile game used for educational purpose in addition to entertainment. It focuses on healthy habits for the heart and is aimed at improving knowledge on diet and physical activity among school-going adolescents.~The game is developed in collaboration with the game development team from the School of Informatics, University of Skövde and the health team from Kathmandu Medical College, Nepal.
Study NCT06668675 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: A serious game known as the 'Happy Heart' will be used as the intervention.
Description: The serious game known as 'Happy Heart' is a mobile game used for educational purpose in addition to entertainment. It focuses on healthy habits for the heart and is aimed at improving knowledge on diet and physical activity among school-going adolescents.~The game is developed in collaboration with the game development team from the School of Informatics, University of Skövde and the health team from Kathmandu Medical College, Nepal.
Study NCT06667609 — intervention group
Intervention type: OTHER
Intervention: Any treatments regimen
Description: Participants may receive any treatments in accordance with standard clinical practice, based on physicians' recommendations and patients' preferences.
Study NCT06334653 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: exercise
Description: acute exercise bout
Study NCT06334653 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: acute exercise bout
Study NCT06604962 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IMES using IEP
Description: First group (n=12) received IMES using inverse electrode placement. The needle electrode inserted into the paraspinal region was connected to the active or cathode pole of the electrical stimulator. The reference or anode pole of the electrical stimulator was connected to the electrode that was inserted into the MTrP area of the UT muscle. The muscle was stimulated for 10 min with a tolerable intensity in a single session to induce muscle relaxation
Study NCT06604962 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: IMES using CEP
Description: Second group (n=12) underwent IMES with conventional electrode placement. In this group, the cathode pole of the stimulator was connected to the needle inserted into the UT muscle, and the anode pole was connected to the needles of the paraspinal region of the cervical spine. Needle electrodes were connected using alligator clip connectors. The muscle was stimulated for 10 min with a tolerable intensity in a single session to induce muscle relaxation.
Study NCT06604962 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham-IMES
Description: Third group (n=12) received sham-IMES. Similar to the experimental intervention groups, the cathode pole of the stimulator was connected to the needle inserted into the UT muscle, and the anode pole was connected to the needles of the paraspinal region of the cervical spine. However, the delivered IMES was very minimal intensity
Study NCT06667193 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
Description: Once thermoneutral procedures are complete, participants in the CI group will be seated in the cold tub and submerged into the water (10º C). The sternal notch of each participant will be used as the anatomical marker to mark submersion point. Participants will sit with both arms outstretched underwater with their backs not touching the sides of the tub. Participants with a shorter stature will be provided an underwater cushion to meet the submersion requirements. The 4-minute timer will begin once confirmation of the participants submersion level and posture is determined. Once completed, the participant will be instructed to slowly exit the tub and allowed to dry and change as necessary.
Study NCT06667193 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold Water Immersion (CWI) - Cold Shower (CS)
Description: Once thermoneutral procedures are complete, participants in the CS group will be instructed to enter the research shower area in Gunter 1610. Within the shower area, the walls of the shower will be numbered from 1 to 4, with 1 defined as facing the faucet, 2 defined as 90° to the right of side 1, 3 defined as 180° from the faucet, and 4 defined as 270° to the right or 90° C to the left from side 1. Participants will be instructed to turn 90° to the right cycling through sides 1 to 4 and then back to 1 every 15 seconds prompted by the researcher. This will allow the participant to complete three full rotations in the shower during the 4-minute intervention time. The shower faucet is modified and oriented in a way where it only produces cold water (10º C) when turned on. Once completed, the participant will be instructed to slowly exit the shower and is allowed to dry and change as necessary.
Study NCT06668272 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Small Changes program
Description: Participants will be asked to track their compliance with their Small Changes diet plan using a simple checklist record . Participants will be asked to follow their diet plan every day. They are encouraged to create a diet plan that is as close to their current diet as possible. Meal options include make-from-scratch recipes, quick grab-and-go options,and restaurant options. There may be some time involved in learning the recipes and the routine of their new diet. It also may alter their grocery spending and habits somewhat
Study NCT06668272 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard behavioral therapy for weight loss
Description: Participants will be provided guidance on cutting and counting calories, setting goals, reading labels, and portion sizes.
Study NCT06463821 — intervention group
Intervention type: OTHER
Intervention: observational questionnaires
Description: Patient data were collected from questionnaires.
Study NCT05304923 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Supraglottic jet oxygenation and ventilation
Description: Supraglottic jet oxygenation and ventilation is conducted using a Wei nasal jet tube (WNJ, Well Lead Medical Co. Ltd, Guangzhou, China) which is connected to a manual jet ventilator (Well Lead Medical Co. Ltd, Guangzhou, China) via its jet port. The initial settings of SJOV are: driving pressure (DP) 15psi, respiratory rate (RR) 20 bpm, inspiratory-to-expiratory (I/E) ratio 1:2, and gas supply 100% oxygen.
Study NCT05304923 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Nasal cannula oxygen supply
Description: Oxygen supplementation at 2 liters min-1 is delivered via a nasal cannula
Study NCT05012449 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arthrography-assisted joystick technology.
Description: Arthrography-assisted joystick technology.
Study NCT05687188 — intervention group
Intervention type: OTHER
Intervention: Blood Sample Collection
Description: Participants will have 40 mL of blood drawn at baseline/pre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.
Study NCT05687188 — intervention group
Intervention type: OTHER
Intervention: Tissue Sample Collection
Description: At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.
Study NCT05687188 — intervention group
Intervention type: OTHER
Intervention: Data Collection
Description: Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.
Study NCT05687188 — intervention group
Intervention type: OTHER
Intervention: Medical Image Collection
Description: Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.
Study NCT06666465 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Operating Room Environment Experienced by Patients Wearing Virtual Reality Glasses Before Surgery The Effect of Surgery Experience on Surgical Fear Level and Care Perceptions
Description: The video, which will be shot for patients to experience the operating environment, will include premedication, an operating room and a post-operative care unit. In the video, the operating room environment will be recorded by the researcher with a voice introduction. The image was shot with a 360-degree camera (Insta 360 One X2), edited with an application program (Insta 360 Studio) and then uploaded to the YouTube VR Pro application as a secret video. The video will be shown to the glasses via an Android phone on the internet via YouTube. People wearing glasses at the screening will be able to look in any direction they want thanks to the 360-degree video. They will be able to watch the video again if they want.
Study NCT06608875 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Hyper-personalized feedback (HPF intervention)
Description: For lower limb motor rehabilitation, the investigator will employ real-time continuous feedback for movement aspects that are specific to each participant's motor deficit. The feedback will be adapted and tailored to each participant.
Study NCT06608875 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hyper-personalized feedback (HPF intervention)
Description: For lower limb motor rehabilitation, the investigator will employ real-time continuous feedback for movement aspects that are specific to each participant's motor deficit. The feedback will be adapted and tailored to each participant.
Study NCT06608875 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted auditory stimulation during sleep (TASS verum intervention)
Description: The investigator aim to reactivate rehabilitation- related memories through the presentation of auditory stimuli during sleep with the goal of promoting motor memory consolidation into stable motor commands
Study NCT06608875 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Control targeted auditory stimulation during sleep (TASS sham intervention)
Description: Identical auditory presentation during the motor rehabilitation training, but not during the night (sham promotion memory reactivation)