AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03487627 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Treatment-as-usual (TAU)
Description: TAU typically involves a discharge planning session by unit staff with the adolescent and their parent(s) to discuss safety monitoring and referrals for mental health services following discharge from psychiatric hospitalization. Investigators will augment this usual care by providing written materials to families outlining some of the key considerations for caring for their adolescent. These written materials will include brochures with information for parents following adolescent suicidal behavior, a listing of resources including instructions for when to call 911 or go to the emergency room, and information regarding the National Suicide Prevention Lifeline. Written materials will be provided to both the enhanced TAU participants as well as participants receiving the electronic and CSM intervention.
Study NCT04715568 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Tablets taken orally
Study NCT05047120 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hypnosis enhanced cognitive behavioral therapy
Description: This therapy entails subjects being induced into a state of relaxation and the receiving cognitive behavioral therapy for pain associated with a new spinal cord injury.
Study NCT05047120 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Education
Description: This therapy entails subjects learning about the causes, mechanisms, and ways to reduce pain associated with a new spinal cord injury.
Study NCT05330819 — intervention group
Intervention type: OTHER
Intervention: Non-interventional
Description: Blood thrombogenicity in patients with previous history of myocardial infarction will be studied using Badimon perfusion chamber, SEM and TEG.
Study NCT05773768 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EHRA-PATHS software tool
Description: Newly developed care pathways integrated into a care-management software tool
Study NCT04737460 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: AAV9/CLN7
Description: Enrollees will receive gene therapy via a viral vector
Study NCT05244226 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl/Hydromorphone
Description: Per routine care
Study NCT05244226 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methadone
Description: Initial dosing 0.1mg/kg, potential to escalate to 0.15mg/kg following interim analysis
Study NCT06091982 — intervention group
Intervention type: PROCEDURE
Intervention: Renal Replacement Therapy (RRT)
Description: Renal Support therapy which consist of procedure of intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration/hemodialysis/hemodiafiltration (CVVH/CVVHD/CVVHDF)
Study NCT05608408 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system
Description: Stimulation of site with the Medtronic Percept PC system using low frequency stimulation at 0.5 Hz.
Study NCT05608408 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Description: Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system using standard of care high frequency stimulation parameters.
Study NCT05351801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: THC (Syndros)
Description: Participants will receive a target dose of 10mg per day of THC (Syndros).
Study NCT05351801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CBD (Epidolex)
Description: Participants will receive a target dose of 800 mg per day of CBD (Epidolex).
Study NCT05351801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: THC + CBD (Nabiximols)
Description: Participants will receive a target dose of 10.8 mg / 10 mg per day of THC + CBD (Nabiximols).
Study NCT05351801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05351801 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06065202 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nutrition Supplement
Description: Total parenteral nutrition (TPN) will be administered within 72 hours of abdominal surgery. Nutritional shakes will be started with a liquid diet and given 3 times a day. This will continue for 4 weeks after discharge.
Study NCT05842915 — intervention group
Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Baseline and 3 month questionnaire
Study NCT05256589 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sona Saliva C-19 Rapid Self-test
Description: Rapid Antigen diagnostic device performance comparative to RT-PCR
Study NCT06358339 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEEM
Description: The TEEM app will provide four types of gamified intervention elements as Routine Tracker, Mind Care, Social Connectivity, and Achievement \& Rewards which providing services including brief contact intervention, mCBT, health education, venting space, mood sharing, etc. Only enrolled participants have access to log in and use the app.
Study NCT04070924 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bandaid
Description: Bandaid dressing
Study NCT04070924 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional bulky soft tissue dressing
Description: Conventional bulky soft tissue dressing
Study NCT04776980 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Post Feraheme Infusion MRI
Description: All participants will receive a ferumoxtyol (Feraheme) infusion 20-28 hours prior to a head MRI. In addition, a blood draw for liquid biopsy targeted tissue sampling during surgery and special iron and macrophage staining on the tumor tissue.
Study NCT04956302 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Given SC
Study NCT04956302 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab and Hyaluronidase-fihj
Description: Given SC
Study NCT04956302 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Given PO or IV
Study NCT04956302 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Panobinostat Lactate
Description: Given PO
Study NCT05230173 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Pragmatic
Description: Patients randomized to a strategy of switching TIM will be switched to one of the preferred agents recommended by clinical guidelines and covered by the patients' insurance formulary as part of routine care, and at the discretion of the site investigator and treating provider. No study-related medications will be provided.~Patients (and their providers) in either treatment arm will be allowed to stop or start new TIMs and other IBD-directed therapies in case of symptomatic relapse or intolerance to therapies, at the discretion of the treating provider-patient team.
Study NCT05420103 — intervention group
Intervention type: OTHER
Intervention: Accelerated Stroke Ambulation Program
Description: Stroke Rehabilitation Program
Study NCT06268431 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxytocin rest
Description: 60-minute oxytocin rest
Study NCT06453174 — intervention group
Intervention type: OTHER
Intervention: Adherence to the first prescribed antipsychotic medication
Description: We shall compare adherence to the first prescribed antipsychotic medication and pragmatic clinical and functional outcomes between two cohorts of patients with first-episode psychosis. One cohort will be comprised of patients treated before the implementation of an early intervention in psychosis model of Personalised Precision Psychiatry including pharmacogenetics, and the other of patients treated under this new model. Also, we shall compare the pharmacogenetic profiles and possible phenocopies (variations of phenotypes produced environmentally, e.g., due to polypharmacy, rather than genetically) between these first episode psychosis patients and a national cohort of patients with longer-term psychotic disorders or with other mental health conditions, to evaluate potential implications for clinical management at different stages of a psychotic illness, and across mental disorders.
Study NCT05602636 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: bupivacaine, midazolam
Description: Patients will be provided with midazolam (up to 2 mg) if requested. No opioids will be administered before the incision. At the first patient complaint of pain, the intraoperative anesthesia team will document the quality and location of pain, and 50 microgram of fentanyl will be administered if the patient requested it or pain score more than 3
Study NCT04565392 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Famotidine 20 milligram tablet
Description: 1 tablet every 12 hours and increase to 1 tablet every 8 hours if not improved by the second day of treatment
Study NCT05185531 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PD-1 plus stereotactic body radiotherapy
Description: neoadjuvant PD-1(Tislelizumab) plus stereotactic body radiotherapy (8 Gy × 3 fractions) in resectable HCC
Study NCT04952506 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-349 F1 Tab.
Description: 1T Single does
Study NCT04565392 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine 20 milligram tablet
Description: 1 tablet every 12 hours and increase to 1 tablet every 8 hours if not improved by the second day of treatment
Study NCT04952506 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKD-349 F2 Tab.
Description: 1T Single does
Study NCT04952506 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: D113 Tab.
Description: 1T Single does
Study NCT05433870 — intervention group
Intervention type: OTHER
Intervention: Whether the PE or E patient combined with PRES
Description: According to the Diagnostic criteria of PRES, all the patients grouped into two groups.
Study NCT05480917 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Patients receiving PsoPlus care
Description: As stated before, both outcomes (via VOS) and costs will be collected. Data on clinical outcomes, such as skin clearance, in the VOS will be collected during follow-up visits at our clinic. Outcomes which are assessed via a questionnaire will be collected using a specialized patient platform (PsoQuest). In addition, for this study the EuroQol 5 Dimensions 5 Level (EQ-5D-5L) questionnaire will need to be filled in. When consultations do not coincide with the time points, data will be collected by a study nurse on a study visit (at our department or the patient's home) and via PsoQuest. A 1 month period will be in place around the time point, meaning that the data can be collected 2 weeks beforehand or afterwards. Cost data will be collected using the TD-ABC approach over the full cycle of care.
Study NCT06172972 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Atraumatic nursing care
Description: Children in the intervention group were allowed to choose a distracting method (foam balloons, stress balls, musical books) to be occupied with during the procedure
Study NCT04846452 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab + Anlotinib + Pemetrexed + Cisplatin or Carboplatin
Description: Patients with non-squamous NSCLC will receive sintilimab, anlotinib hydrochloride, pemetrexed, and cisplatin or carboplatin.
Study NCT04846452 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab + Anlotinib + Albumin Paclitaxel + Carboplatin
Description: Patients with squamous NSCLC will receive sintilimab, anlotinib hydrochloride, albumin paclitaxel, and carboplatin.
Study NCT06343610 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Active product
Description: Contains a complex of: Calaguala leaves extract (Polypodium leucotomos), vitamin C (L-ascorbic acid), blood orange fruit extract (Citrus sinensis), vitamin E (alpha-tocopheryl acetate), vitamin A (retinyl palmitate), vitamin D3 cholecalciferol.
Study NCT06343610 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: No active ingredients.
Study NCT06184672 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dry needling
Description: the area is disinfected by the use of 0.5% chlorhexidine digluconate alcohol solution. The physiotherapist in charge of the intervention uses sterile nitrile gloves, using dry needling needles with dimensions of 0.30 x 50 mm is used. This technique, designed by Hong, applies speed both at the entrance, in order to provoke the local spasm response and at the exit. The inputs and outputs are performed until the REL disappears or until the tolerance threshold of the patient is reached.~Immediately after performing the puncture, ischemic compression is performed on the treated muscle, in order to decrease the duration and intensity of post-puncture pain. For this, a digital pressure is made to the point where the patient's sensation ceases to be pressure and becomes pain. Once the patient is noted that pain is repeated again the art up to a total of 2 minutes
Study NCT05387941 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone Ophthalmic
Description: one drop daily in each eye with retinopathy of prematurity of a predefined stage.
Study NCT05539092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: changing angle of bed
Description: Before the cardiac catheterization procedure: patients' demographic characteristics and health relevant data will be collected on the first day of admission. the researcher will change angle of bed from 15° to 45°.
Study NCT05815043 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low-sodium intake
Description: Participants will consume less than or equal to 720 milligrams of sodium per day for 3 days.
Study NCT05815043 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: High-sodium intake
Description: Participants will supplement their existing diets with 10 salt tablets daily for 3 days.
Study NCT05854056 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Accelerated rehabilitation protocol
Description: See Arms section
Study NCT06491875 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Storytelling (DST)
Description: The DST activity emphasized the use of multimedia to bring the stories to life. At the beginning of the workshop, interactive circles were formed for informative interactions. Children with autism and typically developing children were asked to prepare a short video reflecting a personal experience from their own lives. The children's habits and interests were identified and they were made to work on preparing materials such as pictures, photographs, handicrafts, dough toys, etc. to be uploaded to the computer program. It was explained that they could also choose from ready-made photos in the video editing/editing program for their stories, and that they could make short audio recordings if they wished. Digital stories are usually prepared as videos that combine audio, video, and video clips to tell a story. The DST study was conducted for 16 hours over two months. During the DST, the mothers who wanted to participate and watch also participated in the study.
Study NCT06491875 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sensory Integration Therapy (SIT)
Description: Sensory integration training for children with ASD was conducted 2 days per week for 2 months. Taking into account the results of the Dunn Sensory Profile Scale, sensory approach strategies were determined for children with ASD, taking into account low and high neurological thresholds and hyper- and hyposensitive responses in the auditory, visual, tactile, vestibular and kinesthetic sensory systems. Sensory-motor activities with deep pressure and proprioceptive stimuli were used for children sensitive to tactile stimuli, and activities with linear and slow vestibular stimuli and resistive movement were used for children with kinesthetic sensitivity. In the intervention, swings, ball pools, ramps, rotation, and fast motion inputs were used in swing for children with hypersensitivity to motion, and sensory materials with different textures, play dough, and some other sensory materials were used for children with hypersensitivity to tactile sensory system.
Study NCT06440915 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Theraputic drug monitoring
Description: High Performance Liquid Chromatography (HPLC) is used to determine the plasma concentrations of isavuconazole
Study NCT03991299 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Botox 200 UNT Injection
Description: Botox will be injected into duodenums of subjects by endoscopy.
Study NCT06440915 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Isavuconazole
Description: Isavuconazole
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Influenza and COVID-19 Combination A
Description: Combined influenza and Pfizer-BioNTech COVID-19 Vaccine
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Licensed influenza vaccine
Description: Licensed influenza vaccine
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 Vaccine
Description: Pfizer-BioNTech COVID-19 vaccine
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Influenza and COVID-19 Combination B
Description: Combined influenza and Pfizer-BioNTech COVID-19 vaccine
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Saline Solution
Study NCT06178991 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Investigational influenza vaccine
Description: Investigational influenza vaccine
Study NCT06665386 — intervention group
Intervention type: PROCEDURE
Intervention: hypothermia
Description: Patients who meet the inclusion criteria and do not meet the exclusion criteria will be randomly assigned to either the control group or the IA-SCI group. Control group patients will receive BMM and EVT. IA-SCI group patients will receive BMM and EVT, and additionally a selective intraarterial cooling infusion. The specific method is as follows:~* Pre-recanalization: During the procedure, a micro-catheter used to deploy the stent retriever is threaded coaxially into the common femoral artery through the guide catheter. The microcatheter is advanced over a microguide wire, traveling up through the neck until it reaches beyond the clot. A 50 mL cold 0.9% saline (4℃) is infused into the ischemic territory at a rate of 10 mL/min via the microcatheter. This enables the cold solution to infuse into the ischemic territory prior to revascularization.~* Post-recanalization: Following vessel recanalization, cold 0.9% saline (4 ℃) is reinfused into the vessel via the catheter at a rate of 22 mL
Study NCT04823884 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: open distal chevron osteotomy
Description: Through a 4-cm-long dorsomedial skin incision the V-shaped osteotomy with the apex 1-2 mm superior to the center of the metatarsal head is performed. The angle of the chevron is 60° to 90°. The direction of the osteotomy is angled toward the center of the third metatarsal head. After shifting the metatarsal head laterally, fixation is achieved by usage of one cannulated screw (3.0 mm or 2.5mm). Prominent bone ridges are resected with a saw. A distal soft tissue procedure is performed in every case through the same skin incision. The adductor hallucis tendon is detached from its insertion at the phalangeal bone and from the lateral border of the fibular sesamoid. The transverse intermetatarsal ligament is released and a T-shaped capsulotomy is performed to allow reposition of the sesamoids. Sesamoid position is controlled by sight. After closing of the medial capsula skin is closed with nylon sutures.
Study NCT04823884 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: minimally invasive distal chevron osteotomy
Description: The osteotomy is performed percutaneously through a dorsomedial incision of 3-5 mm. An electric motor-driven machine used for the osteotomy. To prevent overheating the reamer is frequently rinsed with sterile saline. The medial eminence is excised and the V-shaped osteotomy is performed. The apex of the osteotomy is identified by fluoroscopy and centered 1-2 mm superior to the center of the metatarsal head. The angle of the osteotomy amounts to 60-90 degrees as well. Bone debris is washed out with sterile saline. A lateral soft-tissue release is undertaken through a separate lateral incision of 3-5 mm. The distal fragment is shifted laterally and fixed with a canulated screw of 3.5mm. Residual bone ridges are reamed. Position of the metatarsal head and the K-wire is controlled by fluoroscopy. The skin is closed with a nylon sutures.
Study NCT04766944 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT04105231 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: Cannabidiol oral suspension
Study NCT04105231 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Risperidone
Description: Risperidone, encapsulated tablet.
Study NCT05596448 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Coccygeal nerve radiofrequency ablation
Description: During the procedure, after imaging the sacral and coccygeal corns with ultrasonography, a radiofrequency ablation needle is inserted at the level of the coccygeal horn and radiofrequency ablation is applied at 90 degrees for 60 seconds.