AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05110898 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fixed-dose of olmesartan 20mg/40 mg + indapamide 1,5 mg
Description: Fixed-dose of Olmesartan 20mg or 40 mg + Indapamide 1,5 mg oral administration, once a day for 12 weeks. Initially, the participant will be treated with Olmesartan 20mg + Indapamide 1,5 mg. If after 6 weeks the diastolic blood pressure is above 90 mmHg, the dose will be changed to fixed dose of Olmesartan 40 mg + Indapamide 1,5 mg.
Study NCT05110898 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isolated drugs Olmesartan (20 mg or 40 mg) and Indapamide (1,5 mg)
Description: Isolated drugs Olmesartan (20 mg or 40 mg) and Indapamide (1,5 mg) oral administration, once a day for 12 weeks. Initially, the participant will be treated with Benicar® (olmesartan) 20mg and Natrilix® (indapamide) 1,5 mg. If after 6 weeks the diastolic blood pressure is above 90 mmHg, the dose of Benicar® (olmesartan) will be changed to 40 mg.
Study NCT04910347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Dosage within 12 weeks after the end of concurrent chemoradiation therapy. Nivolumab 360mg Intravenously administered every 3 weeks.~As a consolidation regimen, administration of Nivolumab is administered for up to a total of 1 year until disease progression or unacceptable to toxicity occurs.
Study NCT04717882 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CDSS-OPTIMED
Description: The CDSS-OPTIMED is a software program that provides the physician with a personalized alert on whether to consider stopping or starting medication for a specific patient.
Study NCT05824949 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: osseodensification drilling
Description: Implant mechanical and biological stability measured using ISQ values at the time of implant placement and at abutment connection for 40 implants placed in the posterior maxillary area using the osseodensification protocol.
Study NCT05824949 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional drilling
Description: Implant mechanical and biological stability measured using ISQ values at the time of implant placement and at abutment connection for 40 implants placed in the posterior maxillary area using the conventional drilling protocol.
Study NCT06633549 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Accidents Prevention Training
Description: Mothers in the education group who participated in the study were informed about the research and their written consent was obtained. Mothers filled out the 'Information Form' then completed the 'Diagnostic Scale of the Mother's Safety Measures for Home Accidents in Children Aged 0-6 Years'. Mothers were helped when filling out the form and their questions were answered. The training program was organized so that there would be a maximum of 5 mothers in each group. The trainings were conducted face-to-face with a PowerPoint presentation and lasted about 40-45 minutes. Question-answer and discussion methods were used during the training. After the training, the mothers were asked to fill out the same scale again one month later. One month after the training, the mothers were interviewed face-to-face and the scale was filled in again and the changes they made at home were recorded.
Study NCT06317376 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MICT with Aerobic exercise on treadmill
Description: MICT 3 session per week with Aerobic exercise on treadmill for 30 minute with moderate intensity.
Study NCT06417437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SSRI
Description: Patients are not masked from the types of intervention they receive. Assessment will be done before and after each intervention. Each group is independent from other groups.
Study NCT06417437 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SSRI
Description: Patients are not masked from the types of intervention they receive. Assessment will be done before and after each intervention. Each group is independent from other groups.
Study NCT06633549 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: Mothers in the control group were informed about the research and the 'Informed Consent Form' was signed. The mothers filled out the 'Information Form' and this process took about 15-20 minutes. Mothers were helped when filling out the form and their questions were answered. In addition, mothers were asked to complete the 'Diagnostic Scale of the Mother's Safety Measures for Home Accidents in Children Aged 0-6' by introducing. A month later, they were informed that they had to fill out this scale again. A month later, the mothers were interviewed face-to-face and allowed to fill out the scale again. After the last test, the mothers in the control group were given 'Home Accidents and Prevention Training for Children in the 0-6 Age Group' and the output of the training presentation was distributed.
Study NCT06317376 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: standard hospital protocol
Description: standard hospital protocol
Study NCT06134908 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multifaceted Intervention
Description: The multicomponent intervention elements include education for clinicians and patients as well as a shared decision-making program among clinicians and patients. A shared decision-making booklet and a mobile application will be used to promote osteoporosis management and fracture practice.
Study NCT06417437 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: rTMS
Description: Patients will be treated targeting either the traditional brain region or new region.
Study NCT06417437 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Neuro-Feedback
Description: Patients under 18 years old will first be considered this treatment before other methods.
Study NCT06417437 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Game Regulation
Description: Patients will learn how to play several games that can supposedly regulate or affect negative emotions.
Study NCT04850287 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Digital Sensors for Population Awareness about Health Issues using Social Media
Description: A clustered randomized control trial will be conducted and ZIP Codes from each demographic environment will be randomly assigned to control and intervention arms. Digital educational materials about organ donation will be exposed to online users in social media belonging to ZIP Codes assigned to the intervention arm
Study NCT06055621 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dasatinib
Description: Daily orally administration of DASATINIB
Study NCT04580407 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TAK-672
Description: B-Domain Deleted Recombinant Porcine Factor VIII
Study NCT05473520 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxycycline
Description: A dose of 100 mg twice daily of doxycycline based on the recommended dose for adults which is commonly used for bacterial infections such as rickettsial infection, lyme disease and pelvic inflammatory disease.
Study NCT05473520 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo + standard anti-tuberculous treatment
Study NCT06522035 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Allocetra
Description: Intra-articular injecton of Allocetra into the target joint.
Study NCT06652763 — intervention group
Intervention type: OTHER
Intervention: Minnesota Living with Heart Failure Questionnaire
Description: Self-administered, validated questionnaire to assess symptoms of heart failure
Study NCT06652763 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiogram
Description: Resting transthoracic echocardiogram to exclude valvular pathology and the assess indices of systolic and diastolic function and speckle tracking for strain
Study NCT06652763 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Six-minute walk test
Description: Standardised, objective assessment of exercise capacity
Study NCT06652763 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Manganese-enhanced MRI and 31-P magnetic resonance spectroscopy
Description: Using a 3-Tesla scanner, 31P magnetic resonance spectroscopy will be performed to obtain information regarding cardiac energetics. An intravenous infusion of manganese dipyridoxyl diphosphate (mangafodipir, MnDPDP) will be commenced at a rate of 1mL/min using a dose of 5µmol/kg (0.1mL/kg).
Study NCT06652763 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiovascular magnetic resonance scan
Description: Scan including adenosine stress perfusion
Study NCT06652763 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood tests
Description: Full blood count, Urea and electrolytes, Liver function tests, Glucose and HbA1c, Insulin and C-peptide, NTproBNP, High sensitive troponin I, storage of plasma for future analyses
Study NCT05273801 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Heart Rate Recording from Multiple Participants, No Visual Feedback
Description: Heart rates are recorded from multiple participants during the group sessions. However during this intervention, it will not be cast to a TV for feedback to the participant or clinician.
Study NCT05273801 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Visual Feedback of Multiple Participant Heart Rates
Description: Visual feedback of HR is provided through a TV monitor. Multiple heart rates can be displayed and recorded simultaneously allowing for group encouragement, continuous monitoring and adjustment of all participants to ensure reaching appropriate target intensity.
Study NCT06541041 — intervention group
Intervention type: DEVICE
Intervention: Brief intraoperative electrical stimulation
Description: Intraoperative brief electrical stimulation (BES) will be performed using a handheld nerve stimulator (Checkpoint Guardian) to stimulate the donor nerves at 2 mA with a 200 µs pulse duration for 10 minutes per nerve.
Study NCT06541041 — intervention group
Intervention type: DEVICE
Intervention: Temporary Postoperative Peripheral Nerve Stimulation
Description: An implantable temporary peripheral nerve stimulator (SPRINT PNS System) will be placed during the surgery with one lead for each donor nerve. The implantable peripheral nerve stimulator will be programmed to optimize postoperative pain control on an individualized basis. The peripheral nerve stimulator will be explanted after 60 days, as is intended for this device.
Study NCT04850287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Sensors for Population Awareness about Health Issues using Social Media
Description: A clustered randomized control trial will be conducted and ZIP Codes from each demographic environment will be randomly assigned to control and intervention arms. Digital educational materials about organ donation will be exposed to online users in social media belonging to ZIP Codes assigned to the intervention arm
Study NCT06167655 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neurostimulator
Description: Neurostimulation system that applies stimulation to nerve pathways in the head associated with migraine symptoms.
Study NCT06167655 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Neurostimulator
Description: Neurostimulation system that applies stimulation to nerve pathways in the head associated with migraine symptoms.
Study NCT04776434 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB)
Description: This study will capture data from the use of the SELUTION SLR according to its approved labelling.
Study NCT06615674 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Forxiga® 10 mg Film-Coated Tablet, manufactured by AstraZeneca Pharmaceuticals LP, USA for AstraZeneca Pharmaceuticals Co. Ltd., China imported by PT AstraZeneca Indonesia, Indonesia
Description: The first group is the Dapagliflozin group, which will get Dapagliflozin 10mg once a day every morning for 14 days. And the second group will have placebo for 14 days.
Study NCT06401993 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: The dao qi tong luo group
Description: The dao qi tong luo group will accept acpuncture. Acupuncture will be performed at acupoints including TE17 (Yifeng), SI19 (Tinggong), GB2 (Tinghui), TE5 (Waiguan), TE3 (Zhongzhu) and etc. Among them, the dao qi tong luo group will make patients feel qi.
Study NCT06401993 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: The acupuncture group
Description: The acupuncture group will accept acpuncture. Acupuncture will be performed at acupoints including TE17 (Yifeng), SI19 (Tinggong), GB2 (Tinghui), TE5 (Waiguan), TE3 (Zhongzhu) and etc. The acupuncture group will not feel qi.
Study NCT06614426 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Test group 1 (T1)
Description: Test group 1 (T1): Open flap debridement using electrolysis decontamination
Study NCT06614426 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Test group 2 (T2)
Description: Test group 2 (T2): Open flap debridement using electrolysis decontamination combined with L-PRF application
Study NCT05342402 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Somatosensory Rehabilitation Program
Description: Somatosensory rehabilitation program includes minimizing contact with the painful zone of the vulva and uses tactile stimulation at a tolerated distance from the vulva. Each participant will also receive advice on resuming sexual activities with vaginal penetration.
Study NCT05342402 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Educational Pain Management Program
Description: Educational Pain Management Program includes education on decreasing irritative contacts with the vulva and relaxation techniques. Each participant will also receive advice on resuming sexual activities with vaginal penetration.
Study NCT06614426 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Control group (C)
Description: Conventional open flap debridement
Study NCT06614946 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Electronic Safety Plan (ESP)
Description: Participants will receive an electronic safety plan in the ED. ESP focuses on developing a personalized coping plan to manage suicidal thoughts and urges.
Study NCT06614946 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text support
Description: Those in the text-based support program will receive up to 2 texts per day for a month with varying levels of tailoring, based on ESP and dynamic personalized feedback.
Study NCT05438732 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: smaller incision, new generation implantable miniature telescope (SING-IMT)
Description: The IMT (model SING) is an intraocular implant comprised of 2 micro lenses in a glass tube (optics) in a flexible silicone carrier (haptics)
Study NCT06478654 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral Modified Pectoral Nerve Block (PECS II).
Description: The procedure will be done bilateral with the patient lying in the supine position and the ipsilateral arm will be abducted and externally rotated, and the elbow flexed 90°.~The block will be managed by in-plane technique. After confirming the location of the needle with 2-3 mL of saline, 10 mL of 0.25% bupivacaine will be injected. Then, the needle will be advanced to the interfascial plane between the pectoralis minor and serratus anterior muscle, and 20 mL of 0.25% bupivacaine will be administered with the same procedure. The Block will be repeated on the other side using similar technique taking into consideration the toxic dose of bupivacaine
Study NCT06478654 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral Thoracic Erector spinae plane block (ESPB).
Description: Under all aseptic precautions and sonar guided, ESP block will be managed at T4 or T5 bilateral using a high-frequency linear ultrasound probeWe will inject 20ml of bupivacaine 0.25% into interfacial plane below to erector spinae, a manifest linear pattern will be visualized uplifting the muscle. The Block will be repeated on the other side using similar technique taking into consideration the toxic dose of bupivacaine.
Study NCT05196633 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: radial extracorporeal shock wave therapy
Description: rESWT (Endopuls 811; Enraf Nonius B.V. Va-reseweg 127, 3047 AT Rotterdam MedTech, Wessling, Germany) will be applied on the myotendinous junction of both the gastrocnemius and the soleus muscles in post-stroke spasticity patients. 2000 shots will be applied on the gastrocnemius and soleus myotendinous junction with a frequency of 10 Hz and energy density of 60 mJ (1 bar) within tolerable pain limits.
Study NCT05196633 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: sham radial extracorporeal shock wave therapy
Description: The control group will receive sound over the myotendinous junction of gastrocnemius and soleus with transducer-like contact.
Study NCT04680910 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: Targeted propofol infusion in TRD patients will induce sedation with maximal expression of EEG slow waves and minimal burst suppression.
Study NCT04680910 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Electroencephalography (EEG)
Description: EEG will be recorded during propofol infusion and during overnight sleep. Sleep EEG data will be acquired for a minimum of one night prior to the first sedation session, providing a baseline measure. Additional overnight sleep recordings will be performed on day of sedation and subsequent nights.
Study NCT04680910 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Slow-Wave Activity
Description: Duration of slow waves during sedation will be evaluated using automated approaches. SWA during sedation will be calculated as the total power in the 0.5-4 Hz frequency band/total time in minutes. SWA during N2/N3 sleep will be calculated as the total power in the 0.5-4 Hz frequency band/total time in minutes in the N2 and N3 sleep stages. Delta sleep ratio will be computed from the SWA measured during the first and second N2/N3 cycles.
Study NCT06063850 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: AAV9-hSyn1-miGRIK2
Description: AMT-260 is an AAV9 gene therapy product that locally delivers miRNA silencing technology to target the GRIK2 gene and suppress aberrantly expressed GluK2 containing kainate receptors. Intervention will be a one-time intracerebral administration of AMT-260.
Study NCT05833360 — intervention group
Intervention type: DEVICE
Intervention: Exai oncRNA blood test
Description: A phlebotomist will collect approximately 40 ml (about 2-3 tablespoons) of blood from the subjects after consent. The Exai oncRNA blood test will be run on the blood samples.
Study NCT06287450 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bivalent RSV Vaccine (IN006)
Description: Formulation for injection
Study NCT06287450 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection
Study NCT05392517 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: self-mobilization technique along with conventional therapy
Description: Group A will be treated with self-mobilization technique of thoracic spine with the frequency of 2 sets of 10 repetitions thrice per week for a total of six weeks and conventional treatment.~Self-mobilization technique will be comprised of self-mobilization technique using tennis balls and foam roller. The participant will be supine with knees in 90-degree flexion.~* Mobilization Technique 1: Cross your arms over your chest so that you are in slight flexion and then slowly begin to move your shoulders and head closer to the floor placing the mid back into extension over the balls joined to make mobilization device. Hold this position for 3 seconds and then return to the flexed position.~* Mobilization Technique 2: Lying lengthwise on the foam roller, clasp your hands together in front of you, above your chest with arms straight. Slowly move your arms above your head until you feel a good stretch. This exercise should be pain free. Hold stretch for 30- 60 seconds.
Study NCT05392517 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: conventional therapy
Description: Group B will be treated with the conventional treatment (heating pad, ultrasound, thoracic strengthening exercises
Study NCT04997720 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Training
Description: Each course will consist of:~1. Initial evaluation~2. Theoretical tutorial~3. Training with exercises of increasing complexity.~4. Final evaluation.
Study NCT05726370 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Immunoglobulin G4 monoclonal antibody, via IV infusion
Study NCT05726370 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CISPLATIN
Description: Platinum agent, via IV infusion
Study NCT05726370 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Platinum agent, via IV infusion
Study NCT05726370 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Antineoplastic agent, via IV infusion.
Study NCT06363981 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active rTMS over the left DLPFC and over the left DMPFC
Description: Active rTMS over the left DLPFC and over the left DMPFC to induce the long term potentiation of stimulated areas.
Study NCT06363981 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active rTMS over the left DLPFC
Description: Active rTMS over the left DLPFC to induce the long term potentiation of stimulated area.
Study NCT06363981 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham rTMS
Description: Sham rTMS over the left DLPFC or over the left DLPFC and over the left DMPFC for placebo.