AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05311384 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Keys Constraint-induced Movement Therapy protocol
Description: All participants will receive the Keys CI Therapy protocol over an 8-week intervention period. Specific CI therapy strategies will be delivered, including: 1) supervised movement training will be carried out for 1 hour for 4 days/week for the first 4 weeks, 2 days/week for weeks 5 and 6, and 1 day/week for weeks 7 and 8; 2) participants will use the restraint mitt on their less-affected UE for most of their waking hours for an 8 week period; 3) transfer package methods will be modified to accommodate the longer time period between clinic visits; and 4) participants will be asked to independently perform additional movement training for 30 minutes each day at home.
Study NCT05657184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REGEND001
Description: Transplantation of REGEND001 for dose escalation.
Study NCT04786184 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CALM Breathing
Description: CALM Breathing is a mind-body breathing therapy that links CO2 changes to dyspnea and anxiety symptoms and targets breathing efficiency and self-efficacy in COPD. CALM Breathing: Individual interoception- based breathing therapy with capnography (non- exercise training) Home Program: Monitored home- based breathing exercises; RR biofeedback; goal setting; exercise logging. Coaching: Motivational interviewing. Personnel: PT, EP, occupational therapist, or nurse. Frequency: 1-hour sessions, twice per week for 4 weeks. Exercises: • 10 core breathing exercises with ETCO2 biofeedback in recovery postures at rest and with body movement (gentle stretches and brief low-moderate intensity physical activity). • Breathing biofeedback (ETCO2, RR, airflow pattern). Education: Education on anxiety; COPD Patient Guide.
Study NCT04786184 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional outpatient PR
Description: After referral to Columbia's outpatient pulmonary rehabilitation (PR) program, participants randomized to the Wait-List control group will be put on a PR wait list (usual care). In Phase II, all participants will receive PR of 1-hour sessions, twice per week for 10 weeks. Traditional outpatient PR: Group exercise training (ET) combined with pursed lips breathing (PLB) training; 1:2 therapist to patient ratio. Home Program: Unmonitored walking exercise 1-2 days/week; no biofeedback monitoring. Coaching: Traditional monitoring and verbal cueing. Personnel: PT or EP. Frequency:~1-hour sessions, twice per week for 10 weeks. Exercises: • ET of muscles of ambulation with exercise equipment, such as on a treadmill or cycle ergometer (30-min), plus 15-min strengthening and posture exercises; O2 supplementation as needed. No breathing biofeedback. • PLB instruction only during exercise training. Education: Verbal and written information.
Study NCT05668780 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: NIATx Coaching
Description: The intervention will consist of:~1. a Nominal Group Technique session to identify priorities in integrating HIV/HCV/MOUD~2. rapid cycle improvement coaching sessions from a NIATx coach, using data dashboards and screening alerts to improve identification and treatment for HIV/HCV/OUD~3. training for primary care providers
Study NCT05436873 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MR-HIFU
Description: MRI guided High Intensity Focused Ultrasound sonication.
Study NCT05401747 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Healthy lifestyle
Description: Nutrition consultation and teaching: A registered dietitian has the responsibility of teaching and explaining the diet. Plan: One meeting per 12 weeks. The exercise program is based on the Physical Activity Guidelines Advisory Committee and American Heart Association guideline and a modified version of Dose-Responses to Exercise Training study protocol for older adults summarized our weekly plans in detail. Plan: 2 meetings per week. Cognitive enhancement: Participants can select any of the following activities:methods requiring mental activities, physical activity, and social activity, enjoying music and our weekly dance classes (Waltz).
Study NCT05029557 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education and telephone follow ups based on the Chronic Care Model
Description: The effects of Chronic Care Model-based education and telephone follow-up given to patients with COPD on self-efficacy and patient-reported outcomes.
Study NCT06318845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DHP2302R1
Description: 75 mg per dose, once daily
Study NCT06318845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DHP2302R2
Description: 50 mg per dose, once daily
Study NCT05675007 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Colon-delivered multivitamin supplement
Description: Colon-delivered multivitamin supplement containing the following dose of the indicated vitamin: vitamin B2 (10 mg), vitamin B3 (4.0 mg), vitamin B6 (1.4 mg), vitamin B9 (400 μg), vitamin C (200 mg) and vitamin D3 (15ug). Vitamin capsules are filled with microcrystalline cellulose and magnesium stearate up to 200 mg. Control of release in the colon is achieved by the Eudragit S 100 coating layer technology that surrounds the vitamins contained in the core capsules.
Study NCT05675007 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsule
Description: Placebo capsule containing microcrystalline cellulose and magnesium stearate up to 200 mg. Placebo capsules are coated with the Eudragit S 100 coating layer.
Study NCT06138145 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Video
Description: Different videos were shown for Arms B and C. No Video was shown for Group A or D.
Study NCT06138145 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video
Description: Different videos were shown for Arms B and C. No Video was shown for Group A or D.
Study NCT06138145 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Survey
Description: Survey about participant's demographics, information source trust, and clinical trials knowledge. Also includes question about whether the participant is interested in enrolling in the Pediatric Trials Notification System.
Study NCT06138145 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Survey
Description: Survey about participant's demographics, information source trust, and clinical trials knowledge. Also includes question about whether the participant is interested in enrolling in the Pediatric Trials Notification System.
Study NCT04126824 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Triamcinolone
Description: 40 mg triamcinolone administered as a Superior Hypogastric Nerve Block (SHNB)
Study NCT04126824 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: 0.5% bupivacaine (20 mL) administered as a Superior Hypogastric Nerve Block (SHNB).
Study NCT04126824 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: 0.5% bupivacaine (20 mL) administered as a Superior Hypogastric Nerve Block (SHNB).
Study NCT04126824 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Iohexol contrast
Description: The appropriate amount of contrast to enable visualization of the nerve block under fluoroscopy given as a Superior Hypogastric Nerve Block (SHNB) will be administered.
Study NCT04126824 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Iohexol contrast
Description: The appropriate amount of contrast to enable visualization of the nerve block under fluoroscopy given as a Superior Hypogastric Nerve Block (SHNB) will be administered.
Study NCT05628259 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Nursing based Motivational Interviewing
Description: A motivational interview (MI) program based on the telenursing approach was applied to the individuals in the experimental group. In this study, the MI procedure includes eight sessions in total, with four sessions of motivational interviews by phone in the first month of the intervention and four sessions of motivational interviews by phone in the next two months for each individual. Pre-tests were collected in the first month. Afterwards, MI intervention was applied for three months. This intervention was applied to the experimental group in addition to the routine care provided by the hospital. MI application took an average of 45-60 minutes via phone call.
Study NCT05651204 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: GABA Blood Level
Description: Blood specimens will be collected by a registered phlebotomist according to hospital's specimen collection procedures.
Study NCT04863183 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CELLISTEM-OA
Description: The intra-articular puncture will be performed by an orthopedic doctor specializing in knee and hip treatments. The procedure will be carried out using sterile technique, after cooling the skin with local ice.
Study NCT04863183 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triamcinolone acetonide
Description: The intra-articular puncture will be performed by an orthopedic doctor specializing in knee and hip treatments. The procedure will be carried out using sterile technique, after cooling the skin with local ice.
Study NCT05459090 — intervention group
Intervention type: OTHER
Intervention: ex-vivo study
Description: ex-vivo experiments in tissue slices obtained from biopsies
Study NCT06437431 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: glenzocimab
Description: Two vials (2x500 mg) of glenzocimab should be administered concomitantly for eligible patients for a total dose of 1g of glenzocimab as an IV infusion over 6 hours, with 1/4 of the dose administered by a 15-minutes bolus and 3/4 of the dose administered by 5h45minutes continuous infusion.
Study NCT06437431 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Placebo of glenzocimab is 0.9% NaCl for IV administration. It is supplied for clinical trial use in vials of 50 mL. Two vials of placebo should be administered concomitantly for eligible patients. The administration scheme will be the same as in the experimental arm.
Study NCT06208956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: In the dexmedetomidine group, dexmedetomidine is infusion intravenously with a loading dose of 0.5 μg kg-1 for 10 min, then infusion at 0.3 μg kg-1 h-1 according to the ideal body weight of the patient until the end of colonoscopy. During the whole process, maintenance Ramsay score of 3 to 4. Propofol 10 mg will be administrated as the rescue dose if body movement occur during colonoscopy.
Study NCT06208956 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Propofol
Description: Propofol is administrated 1 mg kg-1 intravenously, then titrated given by 0.5 mg kg-1 until Ramsay score reach 3. During the whole process, propofol is given intermittently to maintain Ramsay score 3 to 4. If body movement happen, propofol 10mg will be administrated every time.
Study NCT04191460 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cRGD-ZW800-1.
Description: Injection of cRGD-ZW800-1 within 48 hours before imaging/surgery
Study NCT06394934 — intervention group
Intervention type: BEHAVIORAL
Intervention: Healthscan App
Description: Participants will use the Healthscan mobile application to monitor and record their daily blood pressure at home. The app allows participants to enter their BP measurements, which are then used to calculate blood pressure variability (BPV). The app's use is intended as a non-invasive, practical tool for patient self-management and longitudinal health monitoring in hypertensive individuals.
Study NCT05369819 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: . Patients of the midazolam group will be treated with midazolam premedication (3 cc mixture of 0.035 mg/kg midazolam and normal saline; maximum midazolam dose, 3 mg) intravenously a waiting area 3 minutes before transportation to an operating room
Study NCT05369819 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Control group patients are treated with 3 cc normal saline in a waiting area 3 minutes before transportation to an operating room
Study NCT05038137 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time restricted feeding
Description: Participants will eat all food during a self selected 8 hour eating window prior to 8:00 PM.
Study NCT05038137 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants will have a daily eating period equal to or greater than 12 hours.
Study NCT05568940 — intervention group
Intervention type: DRUG
Intervention: Tibolone 2.5 Mg Oral Tablet
Description: Tibolone oral therapy for 2-3 months: All participants will take a Tibolone 2.5 mg tablet orally daily, at the same time each day, following a scheduled, luteal-phase injection of leuprolide acetate 11.25mg intramuscular (IM).
Study NCT05297266 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IscAlert
Description: Insertion of a CO2- and temperature sensor in the distal part of the replanted extremity
Study NCT06428214 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Restylane Shaype
Description: Injection
Study NCT06428214 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Restylane Shaype
Description: Injection
Study NCT06428214 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Restylane Defyne
Description: Injection
Study NCT06428214 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Restylane Lyft lidocaine
Description: Injection
Study NCT04536220 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Endoscopic Ultrasound (EUS), Fine Needle Aspiration
Description: Endoscopic Ultrasound (EUS), Fine Needle Aspiration, which are routine clinical operations
Study NCT04196257 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide)
Description: Dose escalation of BP1001-A intravenously (IV), twice weekly for 4 weeks (28-day cycle) for 6 cycles.
Study NCT04196257 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BP1001-A (Liposomal Grb2 Antisense Oligonucleotide) with paclitaxel
Description: Dose expansion of BP1001-A IV twice weekly (Maximum tolerated dose or Maximum admistered dose) plus paclitaxel IV weekly for 4 weeks (28-day cycle) for 6 cycles.
Study NCT05516563 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: EDucation and eXercise intervention
Description: The exercise programme includes 3 key streams:~1. Low-load isometric abduction~2. Functional loading~3. Abductor loading: Graduated abductor loading, designed to improve load tolerance by applying progressively higher loads across the abductor muscles. Daily exercise will be completed three days a week at a 'hard' to 'very hard' level, alternating with three 'light' days and one rest day. The clinic day will constitute one of the 'hard' days.~Education will be delivered via a 20 minute video which focusses on understanding and managing lateral hip pain ( ie pain associated with gluteal tendinopathy). Education will also be tailored to each patient on attendance with the physiotherapist at the 6 clinic visits
Study NCT06299371 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab
Description: Adebrelimab IV
Study NCT06299371 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paclitaxel for injection (albumin bound)
Description: paclitaxel for injection (albumin bound) IV
Study NCT06299371 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin or Carboplatin
Description: Cisplatin or Carboplatin IV
Study NCT05027360 — intervention group
Intervention type: DRUG
Intervention: SNP - Sodium Nitroprusside
Description: The primary objective of our study is to assess the efficacy and safety of SNP as part of the treatment regimen of AHF patients and to identify predictors of efficacy.
Study NCT04922047 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tislelizumab and BCG
Description: Tislelizumab 200 mg administered by intravenous infusion every 3 weeks in first year and continue to second year based on physician choose. BCG 120 mg induction therapy administered via intravesical instillation (once weekly for 6 weeks). BCG induction therapy is followed by maintenance therapy (once weekly for 3 weeks at months 3, 6, 12, 18, 24m).
Study NCT05735210 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polso™ Watch blood pressure measurement compared to a reference blood pressure measurement
Description: The referenced blood pressure measurements are taken by dual auscultators.
Study NCT05488756 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group 1
Description: Physical therapy agents and isometric exercise training will be applied to the patients. These will be administered a combination of transcutaneous electrical nerve stimulation, ultrasound, a hot pack, and isometric training 3 times a week for 4 weeks by the physical therapist.
Study NCT05488756 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 2
Description: Physical therapy agents and deep cervical flexor muscle training will be applied to the patients. These will be administered a combination of transcutaneous electrical nerve stimulation, ultrasound, a hot pack, and muscle training 3 times a week for 4 weeks by the physical therapist. Training of the craniocervical flexor muscles is going to be focused on the deep flexor muscles such as longus capitis and longus colli muscles, making neck flexion, not the head.
Study NCT05488756 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group 3
Description: Physical therapy agents and core stabilization training will be applied to the patients. These will be administered a combination of transcutaneous electrical nerve stimulation, ultrasound, a hot pack, and stabilization training 3 times a week for 4 weeks by the physical therapist. These exercises will be performed for 10 repetitions with 10 seconds of contraction and 5 seconds of relaxation.
Study NCT05490706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bodyweight interval exercise
Description: Performing 15 minutes of bodyweight interval exercise after dinner at home by following a video
Study NCT05830110 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Vibrotactile Coordinated Reset
Description: Gloves providing vibrotactile coordinated reset stimulation
Study NCT05830110 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham vibrotactile coordinated reset
Description: Gloves providing sham vibrotactile coordinated reset stimulation
Study NCT05490706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Walking
Description: Performing a 30 minute minute walk after dinner at home
Study NCT06373874 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heel blood collection in a newborn simulation model
Description: The person who will take heel blood in the newborn simulation model can prepare the materials.~Firstly, the blood sample can fill in all the information on the filter paper. Knows where the baby's face should be. It can determine the area where a heel blood sample can be taken.It can gently warm the heel area for a few minutes. The area can be cleaned with alcoholic preparation (cotton/swab, etc.). He can squeeze the heel with his thumb and index finger in front. The other 3 fingers can be rubbed at the back. May stroke the heel three times. The heel can be pierced once with a lancet at a suitable location. He can relax his hand. He can wipe away the first drop of blood. It can create a large thick drop of blood to be collected on filter paper. It can make the drop fill the entire ring on the filter paper with one touch. After the procedure is completed, the heel can be pressed.
Study NCT04744974 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diet intervention
Description: Participants will be given dietician counseling on their assigned diet
Study NCT06333197 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ORIF through transparotid approach
Description: The Retromandibular Transparotid approach is a surgical method used to access structures in the parotid gland region by making an incision behind the mandible.
Study NCT06333197 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ORIF through retroparotid approach
Description: The Retromandibular Retroparotid approach, also known as the Modified Blair Incision, is a surgical technique used to access structures within the parotid gland region by creating an incision behind the mandible and extending it into the parotid region.
Study NCT06472986 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Activity-based therapy and transcutaneous spinal cord stimulation
Description: Activity Based Therapy (ABT) is a method of neuro-rehabilitation that incorporates a high intensity, long duration and effortful engagement from the individual receiving therapy, to garner improvements in sensory and motor function. The ABT constitutes 4 types of exercises including: cardio-fitness, resistance, postural/weightbearing and functional exercises. TransCutaneous Spinal Cord Stimulation (TCSCS) stimulates spinal networks in the cervical region to neuro-modulate the descending motor commands/motor intentions from the brain, which control the muscles. In tCSCS, electrical stimulation is delivered at a frequency of 30-50Hz at 500-1000µs between C3-C7. 12 sessions of ABT (4 weeks), followed by 28 sessions of ABT-TCSCS (7 weeks). Each session will last 1 hour and delivered 3 times per week.
Study NCT05323825 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Fermented milk product containing a probiotic
Study NCT05323825 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Product with identical characteristics to the experimental product.