AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06020898 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Patients with acute ischemic stroke included in the study are randomly assigned to low-dose sodium valproate group, high-dose sodium valproate group and placebo group. Besides receiving conventional treatment for stroke, 10mg/kg sodium valproate, 20mg/kg sodium valproate or normal saline were given intravenously for 3 consecutive days, respectively.
Study NCT05486962 — intervention group
Intervention type: BEHAVIORAL
Intervention: Remote Patient Monitoring
Description: Patients undergoing elective abdominal surgery will be asked to use a wearable activity tracker, vivosmart®HR by Garmin, pre and post-operatively to help remotely monitor health metrics. Data collected through the Garmin device will be reviewed to assess compliance and improvement in activity. Aggregate data will be analyzed to assess feasibility and effectiveness of this device in improving patient recovery.
Study NCT05062759 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tezepelumab
Description: 210 mg SC injection Q4W.
Study NCT05062759 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: SC injection Q4W.
Study NCT04735874 — intervention group
Intervention type: OTHER
Intervention: Evaluate vascular disease risk factors in children with Down Syndrome
Description: We will determine CV disease risk profiles in children with DS at our centers. We will compare these data to published national norms of children without DS. Risk factor data will include: anthropometric measures; blood pressure; history of congenital heart disease and associated surgery, sleep apnea, hypothyroidism, and cancer; fasting blood draw \[lipid panel with subfractions (NMR), insulin, glucose, and CRP\].
Study NCT04735874 — intervention group
Intervention type: OTHER
Intervention: Determine the associations between cardiovascular disease risk factors and markers of early atherosclerosis in children with Down Syndrome
Description: We will perform PWV, CIMT, and CD studies in children with DS and compare these data to available data in children without DS. We will also perform multivariable analysis of the influence of combinations of CV disease risk factors on markers of early atherosclerosis in children with DS. Hypothesis: CV disease risk factors will correlate with markers of early atherosclerosis in children with DS but the associations between risk factors and markers of early atherosclerosis will differ between children with DS vs. the general population of children.
Study NCT04757493 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Prucalopride 2mg
Description: Both prucalopride 2mg and placebo will be administered for 6 weeks. Primary outcome will measure at 2nd and 6th week of treatment.
Study NCT04757493 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prucalopride 2mg
Description: Both prucalopride 2mg and placebo will be administered for 6 weeks. Primary outcome will measure at 2nd and 6th week of treatment.
Study NCT05083689 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Injections of 1.25 mg of intravitreal bevacizumab with Timolol and Dorzolamide
Description: 31 cases in intervention group receive injections of 1.25 mg of intravitreal bevacizumab monthly for 3 months (months 0, 1 and 2) with topical drops of Timolol twice a day and Dorzolamide twice a day
Study NCT05083689 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Injections of 1.25 mg of intravitreal bevacizumab with artificial tears
Description: 31 cases in control group receive intravitreal injection of 1.25 mg bevacizumab monthly for 3 months (months 0, 1 and 2) plus artificial tears (twice a day as a placebo)
Study NCT06352476 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Hygiene Training
Description: The effect of sleep hygiene education in a pre-test quasi-experimental study.
Study NCT05294926 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rocuronium
Description: After applying standard monitoring of pulse oximetry, ECG, noninvasive blood pressure, general anesthesia will be induced with fentanyl 1 µg/kg and propofol 2-3 mg/kg and Rocuronium 0.6 mg/kg will be administered for muscle relaxation after loss of consciousness, under the guidance of neuromuscular blockade monitoring. Tracheal intubation will be performed at a train-of-four count of 0. After that end-tidal carbon dioxide and temperature will be continuously monitored during the procedure. Mechanical ventilation will be instituted with o2:air of 4 L/min, tidal volume of 6-8 ml/kg and respiratory rate appropriate to achieving end-tidal carbon dioxide of 30-35 mmHg. no positive end-expiratory pressure; and inspiratory/expiratory ratio 1: 2. The patient's position will then be changed from supine to prone. Ephedrine 4 mg (if mean arterial pressure \< 60 mmHg and heart rate \< 40 bpm), or atropine 0.5 to 1.0 mg (if heart rate \< 40 bpm) are used to prevent hypotension or bradycardia
Study NCT05294926 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: nerve stimulator
Description: Neuromuscular blockade monitoring will be established and continuously monitored after induction using the Train Of Four (TOF) at the adductor pollicis muscle on the opposite hand and wrist to radial artery cannulation. Two surface electrocardiography electrodes will be placed on cleaned skin overlying the ulnar nerve, with one electrode positioned on the ulnar side of the flexor carpi radialis tendon and the other positioned 3cm proximal to the first. The transducer is then positioned with the flat side against the thumb. Supramaximal stimuli will be applied after autonomic calibration of acceleromyograph after an initial tetanic stimulus. After confirming a train-of-four ratio of 95 to 105%, neuromuscular blockade monitoring will start. The train-of-four mode of supramaximal stimulation (0.2 ms duration, frequency 2 Hz, two s duration) will be applied at 15 s intervals, which last until the end of anaesthesia.
Study NCT06239740 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electroacupuncture group
Description: The acupuncture needle was placed on the scalp at a Chinese traditional acupuncture point. Subsequently, a small electrode was attached to the needle. A minor amount of electricity runs through the electrode, producing a slight vibration or soft hum during the treatment.
Study NCT06239740 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture
Description: participants received acupress or a brief needle insertion at He gu on both hands during the first and 10th weeks, marking the endpoint of the study
Study NCT05364892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Blood samples (80 mL)
Description: Blood samples (80 mL) at inclusion, once a year for 5 years, and if relapse or change of treatment
Study NCT05364892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Fecal samples
Description: Fecal samples at inclusion
Study NCT06098482 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile Research App (MRA)
Description: The MRA (research tool) is a platform used for the delivery of speech perception material in-clinic outside the sound booth or in the home of the hearing-impaired recipients. The MRA speech testing module delivers speech material via streaming to the single implanted ears of cochlear implant recipients. The recipient listens to the speech material and responds with what was heard via the app. Speech is streamed via Bluetooth from the iOS device to the sound processor of the CI-recipient.
Study NCT05364892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Urinary sample (20-40 mL)
Description: Urinary samples at inclusion, once a year for 5 years, and if relapse or change of treatment
Study NCT05364892 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaires
Description: Questionnaires at inclusion, once a year for 5 years, and if relapse or change of treatment
Study NCT05220709 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: bio impedance spectroscopy by means of the Body Composition Monitor (Name of the device is BCM from Fresenius Medical Care D GmbH)
Description: The Body Composition Monitor provides information about the hydration status by a bioimpedance spectroscopy measurement of the body composition from which the level of overhydration can be derived. Four electrodes are used per measurement. All subjects get electrodes attached, following the wrist-ankle approach, in a tetrapolar arrangement. Two electrodes are placed on the hand: one on the wrist, and the second on the dorsal side of the metacarpalia, close to the phalanges. The other two electrodes are placed on the foot: one on the ankle, and the second on the dorsal side of the metatarsals, close to the phalanges of the toes. Age, gender, height, weight and blood pressure are registered in the device before starting the measurement. If the quality calculated by BCM is \< 60%, the measurement will be repeated again. Measurements are taken under supervision of a trained technician or nurse.
Study NCT06098482 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SOC/validated delivery of the speech perception test material
Description: This involves the delivery of speech perception test material in the sound booth in a clinic.
Study NCT04573829 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Home visit
Description: Psychologist come once a week for the carer and three times a week for the patient
Study NCT05474352 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Allon System
Description: Water garments (Allon system) already pre-filled with warm water will be set up before induction of anesthesia. After the induction of general anesthesia, the water garment will cover the lower and upper extremities, the lateral portion of the chest, and the entire back of the patient, which accounts for 70% of the body surface. The water garment will be opened temporarily on the upper extremities for intravenous access and arterial line placement and will be continued intraoperatively until the patient is transferred from the OR table to the stretcher
Study NCT05001035 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time of assessment
Description: Immediate and after one month and after two months
Study NCT05546151 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986322
Description: Specified dose on specified days
Study NCT05546151 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo for BMS-986322
Description: Specified dose on specified days
Study NCT05201118 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selinexor
Description: Selinexor, 20 mg/tablet, is a first-in-class, oral Selective-Inhibitor-of-Nuclear-Export (SINE) compound that impedes XPO-1which is a major nuclear export protein of macromolecular cargo frequently overexpressed in MM.
Study NCT05201118 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CT103A
Description: CT103A consists of autologous T lymphocytes transduced with anti-BCMA CAR lentiviral vector that containing a unique CAR structure with a fully human single-chain variable fragment (scFv).
Study NCT06540534 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: In the adjuvan group (dexamethasone)group, a total of 25 ml of local anesthetic mixture will be applied, consisting of 23 ml of 0.5% bupivacaine and 2 ml of dexamethasone(8mg).
Study NCT06540534 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: kontrol group
Description: In the control group, a total of 25 ml of local anesthetic mixture will be applied, consisting of 23 ml of 0.5% bupivacaine and 2 ml of 0.9% saline.
Study NCT06196632 — intervention group
Intervention type: DRUG
Intervention: Peginterferon-α; Nucleoside analogs
Description: Patients with chronic hepatitis B were treated with the combination of peginterferon-α and nucleoside analogs
Study NCT05567354 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF614
Description: PF614 100 mg capsules
Study NCT05567354 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone
Description: Oxycodone HCl IR 40mg
Study NCT05567354 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo powder
Study NCT04363983 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Liver biopsy
Description: An intraoperative liver biopsy will be performed at free edge of liver with a triangular sample for local resected patients.~This biopsy will be done with scissors, then patients will receive intraoperative hemostasis with mono- or bipolar coagulation. This procedure will be under laparoscopy or laparotomy without extending standard processing time.~This biopsy seeks to allow the evaluate liver modifications testifying the preparing for premetastatic niche, which would allow to identify the patients with risk for hepatic relapsing; the same analysis on the tumors will be performed.
Study NCT04363983 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Stool collect
Description: Stool collection will be performed for all patients at baseline, at 1 month post-operative for resected patients (+ at the end of neoadjuvant treatment / before surgery if patient receives neoadjuvant treatment), and at 2-3 months after the beginning of the treatments in patients with metastases (+ at each progression).~Analysis will be performed for microbiota and metabolism analysis.
Study NCT05853341 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RID-TDS 13.3 mg/24 h
Description: 3 consecutive applications of 1 patch (1st patch for 4 days, 2nd patch for 3 days, 3rd patch for 4 days) covering an 11-day period
Study NCT05853341 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exelon® 13.3 mg/24 h
Description: 11 consecutive applications of 1 patch (each patch will be applied for 1 day) covering an 11-day period
Study NCT06265181 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes coaching
Description: Diabetes coaching intervention will be provided to the participants in the intervention group by the researcher, who is a specialist nurse who has received 140 hours of Level 2 Professional Coaching Training and 20 hours of diabetes coaching training. Since each individual's needs and values will be different, diabetes coaching interventions will be tailored specifically to the individual by the researcher within the general coaching framework, but by taking into account the individual's views, awareness, needs and current situation regarding self-management regarding diabetes. This flexibility, which supports the individual-specific approach within the coaching paradigm, is among the key elements in the success of coaching interventions (43). The individual will determine the coaching agenda according to his/her own needs.
Study NCT06005181 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music listening
Description: Daily music listening
Study NCT06005181 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Piano training
Description: Daily piano practice
Study NCT06262386 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin based chemottherapy
Description: adjuvant therapy for high risk patient
Study NCT06461702 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YOLT-101
Description: The IP is administered intravenously at the predetermined dose.
Study NCT05774301 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: simulation-based training
Description: the training will include a theoretical \& practical parts
Study NCT05355064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trehalose
Description: Enrolled subjects will daily take 4 g of trehalose in oral administration for 24 weeks.
Study NCT05199051 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Gemtuzumab ozogamicine - Cytarabine - Gilteritinib
Description: See Arms description paragraph
Study NCT04958369 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided axillary venous access
Description: Venous access is obtained through ultrasound-guided axillary vein puncture and Seldinger technique.
Study NCT04958369 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cephalic venous access
Description: Venous access is obtained through cephalic vein cut-down.
Study NCT06014346 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychological strategy
Description: * flyer given at the interview presenting the 4 most frequent fears as well as a description of the recommended muscular and breathing exercises,~* then realization accompanied by a training of these exercises
Study NCT06014346 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiological strategy
Description: - ingesting a salty snack
Study NCT04864639 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transition of Care Model
Description: Participants with diabetes, Hispanic/Latinos, adults will receive newly developed discharge instructions.
Study NCT04702412 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Opal patient portal and smartphone application combined with the I-Score patient-reported outcome measure
Description: HIV patients will complete the I-Score PROM via Opal (patient portal) prior to three consecutive clinic visits with their HIV physician who is expected to access their PROM results in time for the visit. The clinic visits will be held at Time 1, Time 2 (3 months) and Time 3 (6 months).
Study NCT06053853 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diphtheria Antitoxin
Description: Dosage form: Solution for injection~Dosage:~1. Perform sensitivity tests, and desensitization if necessary.~2. Give the entire treatment dose of antitoxin IV (or IM) in a single administration (except for series of injections needed for desensitization).~3. The recommended DAT treatment dosage ranges (pediatric and adult) are:~   * Pharyngeal or laryngeal disease of 2 days duration 20,000 - 40,000 unit~  * Nasopharyngeal disease 40,000 - 60,000 unit~  * Extensive disease of 3 or more days duration, or any patient with diffuse swelling of neck 80,000 - 100,000 unit~  * Skin lesions only (rare case where treatment is indicated) 20,000 - 40,000 unit
Study NCT06392958 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Chinese Medicine exercises - Baduanjin
Description: According to the four steps of the cross-theoretical model, the behavior stage (pre-intention stage, intention stage, preparation stage, action stage and maintenance stage) and the family empowerment (clarify the problem, express the emotion, formulate the plan, implement the plan, and evaluate the effect). Combined with the characteristics of elderly patients after PCI, the cardiac rehabilitation management plan was designed focusing on the timing of cardiac rehabilitation, the way of health guidance, safety and compliance management.
Study NCT00798616 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: prednisolone or methylprednisolone
Description: either prednisolone 2mg/kg PO once daily or methylprednisolone 1.6mg/kg IV once daily (if IV access is present) for length of hospitalization, for a maximum of seven days
Study NCT00798616 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: oral or IV placebo
Study NCT04967976 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TiLoop Bra mesh in expander-implant breast reconstrution
Description: The tissue expander is inserted with TiLoop Bra mesh in the first stage of reconstruction immediately after nipple/skin-sparing mastectomy. The tissue expander is placed sub-pectoral.
Study NCT04967976 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: sub-pectoral expander-implant breast reconstruction
Description: The tissue expander is inserted without TiLoop Bra mesh in the first stage of reconstruction immediately after nipple/skin-sparing mastectomy. The tissue expander is placed sub-pectoral and covered by muscle/fascia.
Study NCT05653414 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: short early psychological care associated with encouragement of early support consultation with generalist practitioner or midwife
Description: 4 consultations with a psychologist over 2 months maximum
Study NCT05653414 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: encouragement of early support consultation with generalist practitioner or midwife
Description: encouragement of early support consultation with generalist practitioner or midwife
Study NCT05229393 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cervical plus Diaphragmatic Manual Therapy plus Breathing Reeducation Exercises
Description: Diaphragmatic Manual Therapy consists of techniques intended to indirectly stretch and mobilize the diaphragmatic muscle fibers. This will help to improve muscle contraction and decrease tension. The experimental maneuvers include the Doming Diaphragmatic Technique as described by Leon Chaitow, Lewit, and the Manual Diaphragmatic Release Technique as described by Leon Chaitow. Both maneuvers are performed in two sets of 10 repetitions, within a 1-minute interval.~Cervical Manual Therapy consists of vertebral mobilization techniques according to the Mulligan technique.~Breathing Reeducation Exercises consist of i) recognition of the abnormal breathing pattern, ii) relaxation techniques for all the primary and accessory respiratory muscles, iii) diaphragm breathing reeducation iv) pursed lips exercise v) reeducation of the normal breathing rate
Study NCT05229393 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Cervical Manual Therapy plus sham Diaphragmatic Manual Therapy
Description: Ultrasound sham as Diaphragmatic Manual techniques. Disconnected ultrasound will be applied in the same position as for the experimental group for 15 min as a placebo treatment.~Cervical Manual Therapy: will consist of vertebral mobilization techniques according to Mulligan -
Study NCT05229393 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physiotherapy Program
Description: Conventional Physiotherapy Program consists of TENS for 15min, Microwave pulsed Diathermy for 10min, soft tissue techniques for 15min