AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06217042 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HR070803; Oxaliplatin; 5Fluorouracil; Calcium folinate
Description: Oxaliplatin 85 mg/m² D1 over 2 hours, followed by HR070803 60 mg/m² D1 over 90 minutes, after the Folinic acid infusion is started. Folinic acid 400 mg/m² D1, IV infusion over 1 hours. 5-FU 2400 mg/m² D1 IV continuous infusion over 46 hours.~These drugs are given once every 2 weeks, 12 cycles, 24 weeks.
Study NCT06217042 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: gemcitabine; capecitabine
Description: Gemcitabine 1000mg/m² is given as an i.v. infusion over 30 minutes, administered on day 1, 8 and 15 out of 28 days. Capecitabine 1660mg/m²/day in two divided doses administered orally for 21 days followed by 7 days'rest .
Study NCT05359458 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotional Freedom Liberation Technique
Description: The investigators will apply Emotional Freedom Liberation Technique
Study NCT05246046 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tiotropium Bromide Monohydrate
Description: In each period, subjects receive single dose of tiotropium consisting of 2 inhaled doses via Easyhaler or 2 Spiriva capsules inhaled via HandiHaler
Study NCT05246046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiotropium Bromide Monohydrate
Description: In each period, subjects receive single dose of tiotropium consisting of 2 inhaled doses via Easyhaler or 2 Spiriva capsules inhaled via HandiHaler
Study NCT05414526 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: InterCARE package
Description: The InterCARE package includes:~1. Healthcare Provider HTN/CVD Curriculum A new HTN curriculum will be developed in collaboration with local stakeholders using KITSO Master trainer program documents (Healthcare provider HIV curriculum), Primary Care Guidelines, HTN/CVD curriculum/protocols trialled in Kweneng District and the CDC Prevention Hypertension Management Curriculum.~2. Adaptation of HIV care EHR for HTN/CVD care EHR modifications will be done to enhance data collection around HTN/CVD care, with input from MoH.~3. Patient and treatment partner sessions Clinic staff will provide in-clinic education and counselling on HTN/CVD to all PLWHIV with a diagnosis of hypertension during their routine HIV clinic visit. All patients will be provided a take-home easy-to-read pamphlet on HTN/CVD risk factor management. All PLWHIV will be asked to bring a treatment partner from their social network at the 2nd study visit so that they can practice role-plays with each other.
Study NCT05594459 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mini invasive analgesic technique
Description: patients will be treated with early interventional neuromodulatory techniques, before high opioids dosages.
Study NCT05594459 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: high opioids dosages
Description: patients will be treated with high opioids dosages
Study NCT05090280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF614 solution
Description: PF614 solution is an oxycodone prodrug
Study NCT04960527 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Tart cherry juice
Description: 250 mL tart cherry juice (30 mL tart cherry concentrate \[CherryActive, UK\] diluted with 220 mL water) is consumed on a single occasion by each participant. This will be consumed immediately following the baseline measurements one laboratory visit.
Study NCT05090280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone Hydrochloride
Description: Naltrexone 50 mg has been selected to be administered on Day -1 (single dose), Day 1 (BID), and Day 2 (single-dose) to reduce opioid-related adverse effects.
Study NCT04960527 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Water
Description: 250 mL water is consumed on a single occasion by each participant. This will be consumed immediately following the baseline measurements one laboratory visit.
Study NCT05090280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nafamostat Mesylate
Description: Maximum dose of 10 mg nafamostat co-administered with PF614 solution. Nafamostat will be dosed as an immediate-release (IR) solution or as prototype extended-release (ER) capsules.
Study NCT05834881 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contingency Management (CM) combined with vocational/educational coaching
Description: Two evidence based practices, CM and vocational/educational coaching, will be combined and delivered by paraprofessional coaches in an intervention named PEERS (Peers Education Empowering Recovery Supports). CM uses positive reinforcement (e.g., chances to win prizes) for clients who abstain from substance use. A standardized and well-validated CM protocol will be used in the proposed study. Vocational/educational coaching assists individuals in completing educational and vocational goals. A workbook developed specifically for vocational/educational coaching in emerging adults will be used in the study.
Study NCT05834881 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency Management (CM) combined with vocational/educational coaching
Description: Two evidence based practices, CM and vocational/educational coaching, will be combined and delivered by paraprofessional coaches in an intervention named PEERS (Peers Education Empowering Recovery Supports). CM uses positive reinforcement (e.g., chances to win prizes) for clients who abstain from substance use. A standardized and well-validated CM protocol will be used in the proposed study. Vocational/educational coaching assists individuals in completing educational and vocational goals. A workbook developed specifically for vocational/educational coaching in emerging adults will be used in the study.
Study NCT06165809 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3015 tablets
Description: TQB3015 is a protein inhibitor
Study NCT06041568 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imvotamab
Description: Administered intravenously
Study NCT06222632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mind diet intervention
Description: These participants will receive four nutrition information sessions, 60 minutes per session, on four consecutive weekdays at the participating community centre. A 7-day sample menu will be developed and explained to the participants as a reference. A nutritionist with the help of a research assistant will conduct each session. The nutritionist-to-participant ratio for each session will be 1:10, 1:11 or 1:12. The following topics will be covered: (1) overview of the MIND diet; (2) discussion with the participants about their ability, motivation and opportunity to adopt the MIND diet; and (3) instruction on how to adopt the MIND diet and how to fill out a logbook for adherence checks.
Study NCT06222632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mind plus FB intervention
Description: The sessions will include four nutritional sessions about the MIND diet and four FB sessions. The participants will be instructed on the MIND diet as previously mentioned. In addition, the MIND-FB participants will undertake four 2 h FB sessions in a country park on four consecutive weekends during daytime hours. The FB sessions will take place during the day if it is sunny, cloudy or lightly raining. The distance covered on each forest visit will be 1-2 kilometres. If it is raining heavily, the session will be cancelled. The participants will gather at the entrance of the country park on the day of FB. The participants will gather at the entrance of the country park on the day of FB. An FB coach will brief the participants and begin the forest trip with a set of experiences on the forest environment. The participants will also be instructed to self-practice FB for 2h per session at weeks 8 \&amp; 12 of the intervention.
Study NCT06222632 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual care
Description: Participants will receive a health talk and be given pamphlets provided by the Department of Health and/or Hospital Authority about the protective factors and risk factors of CVDs.
Study NCT05088564 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hand-sewn
Description: Doudenojejunal anastomosis by hand-sewn method
Study NCT05088564 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hemi-double stapling
Description: Doudenojejunal anastomosis by hemi-double-stapling method EEA25 - Covidien EEA Circular Stapler DST Series 25.0mm x 4.8mm is used for anastomosis
Study NCT04917146 — intervention group
Intervention type: OTHER
Intervention: Self-administered questionnaires for relatives (caregivers=CG)
Description: Sociodemographic and medical information for the patient and the CG. SF36 questionnaire for the quality of life (physical, mental) of family CGs This assessment will be supplemented by specific questions relating to: physical health, emotional state, personal and leisure activities of the caregiver.~The CG's knowledge and representations of the disease : questions adapted from the Brief-IPQ disease representation questionnaire.~Questions will also focus on the caregiver's reactions to the patient's illness.~We have constructed a questionnaire to assess the main areas of aid in the context of SSc: emotional, domestic help, administrative, medical, for trave (16 items and an open question).~The CG Reaction Assessment-CRA questionnaire to assess the positive and negative dimensions of helping (24 items). It assesses five dimensions: self-esteem, financial impact, impact on health, impact on time and lack of family support.~The reason for the assistance provided.
Study NCT05230134 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cervical sympathetic block
Description: All participants will get the cervical sympathetic block and catheter under ultrasound guidance.
Study NCT05269914 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Autologous anti-CD19 CAR-T cell injection
Description: According to preclinical research, existing preliminary clinical data and similar approved therapeutic products (kte-c19 of Kate company, the trade name is yescarta ®） According to the clinical trial results, three doses (the number of cells per unit body weight) were selected as the therapeutic dose of this study. Among the patients who increased the dose according to the 3 + 3 design, the number of target cells in each dose group was: (1) the first dose group was 1.00 × 106 Car + T cells / kg, 20% dose error is allowed. (2) the second dose group is 3.00 × 106 Car + T cells / kg, 20% dose error is allowed. (3) the third dose group is 9.00 × 106 Car + T cells / kg, 20% dose error is allowed.
Study NCT04728958 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gratitude
Description: A positive psychology intervention using expressions of gratitude
Study NCT04728958 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Gratitude
Description: A positive psychology intervention using expressions of gratitude
Study NCT04735263 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Atorvastatin 80mg
Description: Patient will be receiving 80mg of Atorvastatin, if they are able to tolerate it from the start to the end of the study.
Study NCT04820595 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: RASS
Description: Richmond Agitation-Sedation Scale
Study NCT04820595 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: CAM-ICU
Description: Confusion Assessment Method for the ICU
Study NCT05425784 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lumoral treatment
Description: The investigational Lumoral treatment -device provides a constant and repeatable application which can be done at home and is easily available. All subjects in the study group will receive their own Lumoral treatment -device and Lumorinse-mouth rinse tablets for the complete duration of the study.
Study NCT05425784 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard oral hygiene self care
Description: Both groups shall be given oral and written instructions for twice-daily standard oral hygiene self-care.
Study NCT05425784 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard oral hygiene self care
Description: Both groups shall be given oral and written instructions for twice-daily standard oral hygiene self-care.
Study NCT05560425 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Koru Mindfulness (KM) Training
Description: The Koru Basic curriculum consists of four weekly interactive 75-minute classes delivered online through Zoom. Each class consists of an overview of 2-3 skills, group practice of the skills, and group reflection. Topics discussed during each training visit include: belly breathing, dynamic breathing, body scan (week 1); walking meditation, gatha (week 2); guided imagery, labeling thoughts (week 3); eating meditation, and labeling feelings (week 4). Participants are instructed to practice a skill for 10 minutes/day and log any reflection on that practice using the Koru phone application.
Study NCT05560425 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Navigating College (NC) Training
Description: With topics discussed from the Freshman Survival Guide book, this training provides a closely matched active control group for KM Training. The training consists of four weekly 75-minute classes delivered online through Zoom. Each class consists of lecture and group discussions on topics related to navigating college. Topics discussed during each training visit include: habits, roommate issues, homesickness, the internet (week 1); strategies when sinking, study skills, getting involved, habit formation (week 2); HALT, gateway habit (week 3); and academic success tips, taking notes, and procrastination (week 4). Participants are instructed to journal about learned information and skills for 10 minutes/day.
Study NCT05881018 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low glycaemic index
Description: Diet will be supplemented with a drink containing a low glycaemic index carbohydrate
Study NCT05881018 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: High glycaemic index
Description: Diet will be supplemented with a drink containing a high glycaemic index carbohydrate
Study NCT05881018 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participants will include physical activity units
Study NCT06125834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab Emtansine (T-DM1)
Description: Enrolled patients will receive Trastuzumab Emtansine (T-DM1) treatment (3.6mg/kg, d1/21, IVD) until progressive diseases or intolerable adverse effects occurs.
Study NCT05841732 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Education; Pain Medication, imaging, referrals to other health services, other health care appointments
Study NCT05841732 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: Education; Pain Medication, imaging, referrals to other health services, other health care appointments
Study NCT05841732 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MyBack Program
Description: A tailored exercise and behavioural change program
Study NCT05397834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals
Description: 2 inhalations of Test and Reference product in each study period
Study NCT05397834 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FLOVENT DISKUS
Description: 2 inhalations of Test and Reference product in each study period
Study NCT05428930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CKDB-501B
Description: Intramuscular injection CKDB-501B
Study NCT05428930 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Botox®50U
Description: Intramuscular injection Botox®50U
Study NCT04133506 — intervention group
Intervention type: DRUG
Intervention: Aspirin 300mg
Description: see earlier (only half of healthy volunteers receive aspirin)
Study NCT06132269 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: AKK formula prebiotic sachet
Description: 5 g/sachet, containing AKK formula, Indigestible Maltodextrin, Crystalline Maltitol, Calcium Carbonate, Citric Acid, Steviol Glycosides, and flavor.~Subjects will consume 1 sachet per day for 8 weeks.
Study NCT06132269 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo sachet
Description: 5 g/sachet, containing Indigestible Maltodextrin, Crystalline Maltitol, Calcium Carbonate, Citric Acid, Steviol Glycosides, and flavor.~Subjects will consume 1 sachet per day for 8 weeks.
Study NCT06610786 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: foldable capsular scleral buckling
Description: Using foldable capsular vitreous body as a novel scleral buckle material to treat the primary rhegmatogenous retinal detachment (RRD) of medium complexity
Study NCT06610786 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vitrectomy
Description: Using vitrectomy to treat primary rhegmatogenous retinal detachment (RRD) of medium complexity.
Study NCT06204341 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: HYPOPRIME treatment
Description: Hypo fractionated pelvic radiotherapy with boost to primary tumour in the prostate with elective lymph node irradiation and minimized androgen deprivation therapy
Study NCT05502367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABI-2280 Vaginal Tablet/Insert
Description: Vaginal Tablet
Study NCT05605678 — intervention group
Intervention type: OTHER
Intervention: No Intervention
Description: This is a non-interventional study.
Study NCT06132451 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Postponement of antihypertensive treatment
Description: Hypertensive blood pressure values in medical in-patients will not be treated during hospitalisation until confirmed by ABPM 4 weeks after hospital discharge
Study NCT05891431 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Untire mobile app
Description: The Untire app is an mHealth intervention (digitally delivered using a smartphone app).~Untire offers a comprehensive program to help you understand cancer fatigue and gives a physical activity program, stress reduction exercises and tips to manage your energy level.
Study NCT06362746 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Non-immunogenic recombinant staphylokinase
Description: 15 mg of drug reconstituted in 15 ml of 0.9% solution of NaCl given as single i.v. bolus over 10-15 seconds
Study NCT06362746 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 15 mg of placebo reconstituted in 15 ml of 0.9% solution of NaCl given as single i.v. bolus over 10-15 seconds
Study NCT06247995 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-NeoB
Description: 68Ga\]Ga-NeoB serves as a radioactive imaging compound to be used for PET imaging for localization of GRPR positive lesions.
Study NCT06247995 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [177Lu]Lu-NeoB
Description: \[177Lu\]Lu-NeoB is a radioligand therapy drug.
Study NCT06247995 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine is a chemotherapy drug.
Study NCT04610346 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Persons with Aphasia Training Dogs Program
Description: Participants will learn and apply positive reinforcement training techniques for working with dogs to train them in basic obedience behaviors (e.g., SIT, STAY).
Study NCT05539027 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Branched-chain amino acids (BCAA), enriched solution (Aminoleban) and L-ornithine L-aspartate (LOLA)
Description: patients will receive branched-chain amino acids (BCAA), enriched solution (Aminoleban) and L-ornithine L-aspartate (LOLA)
Study NCT05539027 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Branched-chain amino acids (BCAA), enriched solution (Aminoleban)
Description: patients will receive BCAA enriched solution (Aminoleban)
Study NCT06589531 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: During TIPS operation, shunt diameter or diameter of covered stent
Description: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment strategy for managing portal hypertension-related variceal bleeding. However, the appropriate diameter of the covered stent during the TIPS procedure remains a subject of debate. To date, there is a lack of strong evidence regarding the most suitable covered stent diameter.~Due to the lack of a dedicated 6-mm covered stent, we first released a 6-mm diameter stent (SD Express; Boston Scientific Co., or Luminexx; Bard Medical Division) in the liver parenchymal segment of the shunt, and then released an 8-mm TIPS stent (Viatorr; WL Gore \&amp;amp; Associates) to create a final 6-mm shunt.
Study NCT06589531 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: During TIPS operation, shunt diameter or diameter of covered stent
Description: After successful puncture, in the 8-mm shunt group, a balloon with a diameter of 6 mm was used to expand the shunt, and then an 8-mm covered stent was implanted (Viatorr; WL Gore \&amp; Associates, Inc.).
Study NCT06596174 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcutaneous spinal cord stimulation (tSCS)
Description: The subjects will undergo 20 minutes transcutaneous spinal cord stimulation (tSCS).
Study NCT06596174 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short-term Machine-Assisted Ankle Movement Training with tSCS
Description: The subjects will undergo 30 minutes of machine-assisted ankle movement training combined with transcutaneous spinal cord stimulation (tSCS) at a time
Study NCT06596174 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Long-term Effects of Machine-Assisted Ankle Movement Training with tSCS
Description: The subjects will undergo machine-assisted ankle movement training combined with transcutaneous spinal cord stimulation (tSCS).~Each session will last for 30 minutes, conducted three times per week, over a period of four weeks.