AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04809662 — intervention group
Intervention type: DRUG
Intervention: Imiquimod
Description: Patients with a diagnosis of actinic keratosis or warts that would be prescribed imiquimod as standard of care will be asked to apply 2 packets (or 2 full pumps) of imiquimod once daily before bedtime for two weeks and then leave on overnight for \~8 hours.~(a) A biopsy will be performed at the baseline visit on the pre-treatment skin and the skin where the medication will not be applied. The skin where the medication will not be applied will act as the negative control. A biopsy will then again be performed on day 10 of imiquimod treatment on the treated skin only, where the study drug was applied.
Study NCT04801537 — intervention group
Intervention type: OTHER
Intervention: normal body temperature and warm extremities
Description: environmental temperature is set according to the standard method to keep normal body temperature and warm extremities
Study NCT04801537 — intervention group
Intervention type: OTHER
Intervention: normal body temperature and cold extremities
Description: environmental temperature is set according to the standard method to keep normal body temperature, but cold extremities
Study NCT06120530 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Intraperitoneal Bupivicaine without epinephrine 30 mg administered following completion of pelvic organ prolapse repair.
Study NCT06120530 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Placebo
Study NCT05895578 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: 1 capsule of probiotic (Lactobacillus CECT 9422 + Bifidobacterium CECT 30257) every 12 hours for 6-months.
Study NCT05895578 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic + placebo
Description: 1 capsule of probiotic + 1 capsule of placebo per day for 6-months.
Study NCT05895578 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 capsule of placebo every 12 hours for 6-months.
Study NCT06352203 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Description: 1 dose of the probiotic every 24 hours, for 6-months.
Study NCT06352203 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 dose of the placebo every 24 hours, for 6-months.
Study NCT04815109 — intervention group
Intervention type: OTHER
Intervention: Encephalography measurement
Description: Encephalography measurement and partially aggravated sedation.
Study NCT05426954 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation utilizing blood flow restrictive therapy
Description: BFR therapy
Study NCT05343572 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Plerixafor
Description: A 20mg single dose of PLERIXAFOR is administered subcutaneously the evening prior to scheduled standard of care surgery for women with AS, AE or RIF for peripheral mobilization of stem cells. For subjects weighing >83 kilogram, the dosing is a single dose of 0.24 milligram per kilogram.
Study NCT06352996 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three-Dimensional Assessment of Maxillary Canine Retraction with Power Arm
Description: A nickel titanium closed coil spring will be stretched from the mini-implant to the power arm will be used for canine retraction.
Study NCT06352996 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three-Dimensional Assessment of Maxillary Canine Retraction without Power Arm
Description: A nickel titanium closed coil spring will be stretched from the mini-implant to the canine bracket will be used for canine retraction.
Study NCT04932525 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Blood and tumor samples for Genetic Profiling research
Study NCT06572397 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: H-1337 1.0%
Description: ophthalmic solution
Study NCT06149442 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of five-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (five incisions).
Study NCT06149442 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of ten-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (ten incisions).
Study NCT06149442 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dose of fifteen-incisions dry needling technique
Description: Once we have assessed the existence of a myofascial trigger point in the levator scapulae muscle, and while the subject is in lateral decubitus on the same side, with a forceps palpation, we apply a rapid in /out dry needling technique (fifteen incisions).
Study NCT05761041 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Fluoride Varnish (5%)
Description: Applied at baseline
Study NCT05761041 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Interviewing
Description: Two MI sessions: face-to-face at baseline and phone call at 3 months
Study NCT05761041 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SDF
Description: Applied bianually
Study NCT05999734 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine
Description: Before skin incision, under complete aseptic precautions and sterilization, the patient will be placed in a lateral position. The spinous process of the fourth thoracic vertebra will be identified and marked. The ultrasound guided MTP block will be done by high frequency linear transducer will be placed in position just lateral to the spinous processes of thoracic vertebra target of the paravertebral space. A 50 mm 22-gauge echogenic needle will be inserted in an in plane technique from a caudal to a cephalad direction and will be advanced. When the needle tip reaches the midpoint between the transverse process and the pleura, 1 ml normal saline will be injected. Once the needle tip has been confirmed and after careful aspiration to demonstrate the absence of air or blood, 0.5mL/kg 0.25% bupivacaine will be injected.
Study NCT05155293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AVT06 (proposed aflibercept biosimilar)
Description: Patients will receive IVT injections of AVT06
Study NCT05155293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eylea® (Aflibercept)
Description: Patients will receive IVT injections of Eylea®
Study NCT05756465 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone-based virtual reality relaxation (SVR)
Description: SVR is virtual relaxation and distraction therapy through a smartphone-based VR device (head-mounted display) that is attached to the head of a cancer patient undergoing chemotherapy, displaying a virtual environment of natural panoramas in 360-degree video and combined with traditional and classic musical instruments. SVR device is paired with smartphone using operating system either Android (minimum generation 11, Android 4.4 KitKat) or OS version 12, minimum screen size of 5.5-inch and maximum of 6.0-inch, screen resolution of at least 1080 x 1920 pixels, can connect to WIFI/ internet and provides a YouTube app to access 360-degree videos. SVR content uses original 360o videos produced by researchers using a video editor software for ± 10 minutes duration.
Study NCT06561321 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tapinarof
Description: Daily topical Tapinarof use will stop disease advancement and improve the quality of life in patients with palmoplantar keratoderma, through its AhR \& NRF2 agonism properties.
Study NCT06641557 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 200mg of Ikt-148009
Description: 4 50mg capsules
Study NCT06639516 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bifidobacterium longum
Description: Bifidobacterium longum
Study NCT06639516 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06639516 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Standard clinical treatment
Description: Fasting, gastrointestinal decompression, rehydration, inhibition of pancreatic fluid and pancreatic enzyme secretion, improvement of microcirculation, and support of organ function if organ dysfunction occurs at a later stage (mechanical ventilation, continuous renal replacement therapy, and the use of vasoactive drugs).
Study NCT06639516 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Standard clinical treatment
Description: Fasting, gastrointestinal decompression, rehydration, inhibition of pancreatic fluid and pancreatic enzyme secretion, improvement of microcirculation, and support of organ function if organ dysfunction occurs at a later stage (mechanical ventilation, continuous renal replacement therapy, and the use of vasoactive drugs).
Study NCT06636916 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Short Intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.
Study NCT06636916 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Long intervals HIIT
Description: Participants will undergo different high-intensity interval training (HIIT) protocols, which involve repeated bouts of exercise at an intensity above 90% of VO2max, followed by recovery periods. The work and rest durations will vary across the protocols to assess the impact on the total time spent at or above 90% of VO2max.
Study NCT06643104 — intervention group
Intervention type: PROCEDURE
Intervention: Tuina
Description: X-ray mapping guides three days of tailored exercises, including 3D therapy, breathing techniques, and spinal manipulation.
Study NCT05179915 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Touch focused on sacral region
Description: In the latent phase of labor, the field energy of the sacral region will be cleared for an average of 15 minutes.
Study NCT05179915 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Therapeutic Touch focused on sacral region
Description: In the latent phase of labor, the field energy of the sacral region will be cleared for an average of 15 minutes.
Study NCT00728533 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Degarelix
Description: Prostate Cancer - Degarelix powder and solvent for suspension for injection. Three-month depot in two dosing regimens.
Study NCT06265818 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.
Study NCT06265818 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation training
Description: Including 1) Basic treatment, including corresponding control of risk factors and education on healthy lifestyles. 2)Swallowing training, including lemon ice stimulation, mendelson maneuver, empty swallowing training, and pronunciation training.
Study NCT06265818 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Breathing Exercises
Description: Active breathing exercises aim to enhance the strength and flexibility of respiratory muscles through a series of exercises, improving breathing patterns and increasing respiratory efficiency. The following are common components of active breathing exercises: 1) Deep Breathing. 2) Chest Expansion. 3) Diaphragmatic Breathing. 4) Coughing Techniques. 5) Expiratory Resistance Training. 6) Gradual Increase in Activity.
Study NCT05806190 — intervention group
Intervention type: DEVICE
Intervention: Continuous Glucose Monitoring
Description: Continuous Glucose Monitoring using a Dexcom G6 Continuous Glucose Monitoring Device
Study NCT06569485 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trilaciclib+R-CHOP
Description: This is a prospective, single-arm, multi-center, phase II clinical study to evaluate the efficacy and safety of Trilaciclib in DLBCL patients treated with R-CHOP.
Study NCT06569407 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online Educational Intervention
Description: An educational program for EBP based on the online learning model was planned to be developed based on the literature and expert opinions. In the program, in line with the literature, the introduction to the EBP, the importance of EBP, EBP steps, clinical research question design in line with PICO, and introduction of EBP databases. It is planned to include topics such as literature search strategies, types of research, use of scientific research and evidence evaluation tools, introduction of clinical decision support systems, reflection of EBP on patient care and clinical decision-making processes, and it is planned to determine the final version of the education content with expert opinions. The program will include recorded videos, slides and documents for each module. The content of the program will be integrated into the Koç University Online Programs Platform by the experts working at Koç University Educational Technologies Unit.
Study NCT06569407 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Educational Booklet
Description: An educational booklet for EBP was planned to be developed based on the literature and expert opinions. The learning objectives and content of the educational booklet to be developed will be created by considering Bloom\&#39;s taxonomy. In line with the literature, it is planned to include topics such as introduction to EBP, importance of EBP, evidence-based practice steps, clinical research question design in line with PICO, introduction of evidence-based databases, literature search strategies, research types, use of scientific research and evidence evaluation tools, introduction of clinical decision support systems, reflections of EBP on patient care and clinical decision-making processes, and finalization of the booklet topics with expert opinions.
Study NCT05405608 — intervention group
Intervention type: DRUG
Intervention: Ondansetron
Description: hemodynamic stability in orthopedic surgeries
Study NCT05914129 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diaphragm, Stomach and Liver techniques
Description: Diaphragm Stretching:~The participant is seating down and the researcher will be behind, placing their hands on the inferior costal border. Cephalic traction is performed during inhalation, remaining during exhalation. Procedure is repeated 2 times, for 10 respiratory cycles, with 1-minute intervals.~Inferior Mobilization of the Stomach:~The participant is seating down with slight flexion of the torso, while the investigator stands behind them, placing the thumbs on the epigastric region. The volunteer will extend their body while the researcher performs a caudal traction. This procedure lasts 5 minutes.~Liver Pump:~Participant is laying on their back, and the investigator is standing on the participants side. The researcher places one hand on the right side inferior costal border posteriorly and the other one bellow the costal border anteriorly. Researcher compresses during exhalation and releases their hands abruptly during inhalation. This procedure lasts 5 minutes.
Study NCT05914129 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stomach and Liver techniques
Description: In this group, techniques are the exact same as described previously but only liver and stomach ones will be performed.
Study NCT05914129 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham technique
Description: In the sham group, manual contact without any therapeutic intention will be performed in the same regions as the experimental groups. This contact will be maintained during the same amount of time as for the experimental group A.
Study NCT06284018 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive Muscle Relaxation Exercises
Description: * Focus on the targeted muscle group.~* Take a slow, deep breath while squeezing on muscle group as hard as she can (not to the point of strain). Keep the muscle tensed for 5 seconds.~Hands and arms, forehead ,Eyes and Cheek, Mouth and Jaw , Neck and Shoulder ,Stomach , Leg and Toes
Study NCT06284018 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates Exercises
Description: Pilates exercise program consisted of floor exercises on a rubber mat, including the following exercises: a- Pelvic Curl. b- Single-Leg Lift. c- Chest Lift. d- Supine Spine Twist. e- Basic Back Extension.
Study NCT06195956 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercise
Description: Exercises done 3 times per weeks, 3 repetitions per exercise for 3 months
Study NCT06195956 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: Exercises done 3 times per weeks, 3 repetitions per exercise for 3 months
Study NCT04667572 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PXL-330 Platinum device for crosslinking with Peschke riboflavin solution
Description: Riboflavin will be used to load the cornea, followed by UV-A crosslinking of the cornea
Study NCT04603560 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audit and Feedback
Description: A report of the provider's hypertension control rates compared to benchmark will be displayed using principles of social norming. We will present that provider's hypertension control rates compared to the 90th percentile of their peers.
Study NCT04603560 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pharmacist E-Detailing
Description: A pharmacist will review the chart in advance and provide a personalized recommendation for how to intensify the specific patient's antihypertensive regimen based on current guidelines. For example, they might recommend adding an additional medication based on the patient's comorbid conditions and could suggest a starting dose and timeframe for dose escalation.
Study NCT06650566 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-299
Description: Administered intravenously
Study NCT06093763 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group without bone grafting
Description: Open wedge corrective osteotomy and plate fixation without bone grafting.
Study NCT06093763 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Group with bone grafting
Description: Open wedge corrective osteotomy and plate fixation with harvesting and using bone from the iliac crest.
Study NCT05346718 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ragweed pollen, birch pollen, clean air (placebo)
Description: Participants are exposed for 4 hours in the Fraunhofer Allergen Challenge Chamber with varying pollen concentrations of ragweed or birch pollen and once with clean air, serving as a placebo exposure.
Study NCT06637241 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Risk stratification care
Description: In this group, Taiwanese adolescent baseball players are categorized into high-risk, medium-risk, and low-risk groups based on injury risk from a previous study. High-risk players receive sports protection education and physician referrals for shoulder and elbow assessments, with further imaging if necessary. Common issues like Little League shoulder and elbow are managed with conservative treatments. The sports protection education includes the Modified Yokohama Baseball-9 (mYKB-9), a program that significantly reduces injuries with exercises targeting shoulder and elbow health. Medium-risk players receive mYKB-9 education only, while low-risk players are observed without changes to their training methods.
Study NCT06591728 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Oral PCA
Description: Administration of 1,000 mg BID of oral PCA in individuals with knee prosthetic joint infection prior to revision surgery
Study NCT06669039 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Computer-controlled Local Anesthetic delivery system
Description: Local anesthesia will be delivered using Computer-controlled Local Anesthetic delivery system.
Study NCT06669039 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Inferior Alveolar Nerve Block
Description: Local anesthesia will be delivered using the conventional syringe
Study NCT04661358 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fenofibrate
Description: Participants begin with a dose of either 160mg or 54mg fenofibrate, based on eGFR value at screening, taken once daily with food. The dose may be adjusted during follow-up based on protocol guidelines.
Study NCT04661358 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants begin with a dose of either 160mg or 54mg placebo, based on eGFR value at screening, taken once daily with food. The dose may be adjusted during follow-up based on protocol guidelines.
Study NCT06670417 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Low level laser therapy watch: The laser watch device was a semiconductor LLL therapeutic apparatus, (model:SL-03 GaALAs semiconductor) Domer Laser Therapy Watch class 3B 650nm low-level laser light
Description: Low level laser therapy watch:~The laser watch device was a semiconductor LLL therapeutic apparatus, (model:SL-03 GaALAs semiconductor) Domer Laser Therapy Watch class 3B 650nm low-level laser light. It provides 18 individual laser beams used for extravascular blood irradiation (transcutaneous) through radial and ulnar vessels at the wrist site.