AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04818801 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant two-component COVID-19 vaccine (CHO cell)
Description: The spike (S) protein is the main surface antigen of SARS-CoV-2, mediates entry of SARS CoV-2 into cells expressing the angiotensin-converting enzyme 2 (ACE2). The RBD interacts with ACE2 and can generate potent neutralizing anti-RBD antibodies.
Study NCT04818801 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal saline (0.9% sodium chloride solution),
Study NCT06400888 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: needle-free subcutaneous injector for Mecbl
Description: needle-free subcutaneous injector for Mecbl
Study NCT06400888 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: intramuscular injection of Mecbl
Description: intramuscular injection of Mecbl
Study NCT04799587 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Magnet at P6
Description: Magnet applied at P6 and attached with adhesive tape. The P6 pressure point is 2 inches proximal to the flexor retinaculum, between the flexor carpi radialis and palmaras longus.
Study NCT04799587 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Magnet applied to arm not at P6 pressure point.
Description: Magnet applied to arm not at P6 pressure point and affixed with adhesive tape.
Study NCT06228222 — intervention group
Intervention type: PROCEDURE
Intervention: renal biopsy
Description: Renal biopsy will be performed for all patients fulfilling the American College of Rheumatology (ACR) criteria to confirm the diagnosis of lupus nephritis (LN) and to classify the glomerular disease by the revised International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2018 histopathological classification system
Study NCT06202300 — intervention group
Intervention type: OTHER
Intervention: Inflammation burden
Description: Coronary artery disease patients undergone multimodality imaging with different level inflammation burden
Study NCT06398041 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood flow restriction training
Description: standard physiotherapy 45 minutes per day, 5 day a week (GAPP) + 2 extra sessions of blood flow restriction training
Study NCT06398041 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Opinions
Description: Healthcare workers in the geriatric rehabilitation ward and patients will be asked on their opinions on GAPP+Care concerning blood flow restriction training
Study NCT06398041 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Opinions
Description: Healthcare workers in the geriatric rehabilitation ward and patients will be asked on their opinions on GAPP+Care concerning blood flow restriction training
Study NCT06412822 — intervention group
Intervention type: OTHER
Intervention: Blood sampling
Description: Blood sampling
Study NCT06412822 — intervention group
Intervention type: OTHER
Intervention: Urine sampling
Description: Urine sampling
Study NCT05481437 — intervention group
Intervention type: DRUG
Intervention: Brentuximab Vedotin
Description: Brentuximab Vedotin injection, 50 mg, once every 2 weeks
Study NCT06576037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBP-1019
Description: Given by vein (IV)
Study NCT05316467 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intensive Lifestyle Intervention (ILI)
Description: * dietary guidance~* exercise guidance~* lifestyle intervention
Study NCT05316467 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Megestrol Acetate 160 MG Oral Tablet
Description: enrolled participants will take Megestrol Acetate 160mg daily
Study NCT05534542 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: exercıse
Description: ıntradıalıtıc core stabılızatıon
Study NCT05469490 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiotherapy (SBRT)
Description: SBRT is specialize radiation that is effective for ablating tumors at primary and metastatic locations that increases antigen uptake/processing/presentation.
Study NCT05469490 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: navoximod
Description: A small molecule inhibitor with potent inhibition of IDO1 enzymatic activity as shown both in vitro and in vivo. As the main function of IDO1 is the regulation of acquired immune tolerance, and its expression in tumor- and dendritic cells in tumor draining lymph nodes negatively correlates with cancer prognosis and survival, navoximod-mediated IDO1 inhibition may restore immune reactivity towards tumors.
Study NCT05469490 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NLG802 (indoximod Prodrug)
Description: An anti-tumor immunomodulator with the active ingredient of 1-methyl-D-tryptophan (NSC- 721782, 1-MT), which is an inhibitor of the indoleamine 2,3-dioxygenase (IDO) pathway that increases the bioavailability of indoximod by leveraging existing mechanisms of absorption, increasing the exposure of indoximod.
Study NCT05320042 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: kalifilcon A Daily Disposable Toric
Description: kalifilcon A Daily Disposable Toric
Study NCT05320042 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultra for Astigmatism Contact Lenses
Description: Ultra for Astigmatism Contact Lenses
Study NCT05414604 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 3D spine CT
Description: CT scan of the spine
Study NCT04971655 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music therapy
Description: Music therapy will be applied throughout diabetes education. Turkish Folk, Classical, Turkish Art and Sufi Music genres will be offered to individuals as an option and will be listened to throughout the process. Instrumental works will be uploaded to the computer by the researchers and will be played on the loudspeaker during the training.
Study NCT05528848 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carfentanil, C-11
Description: Investigational radiotracer to be injected by IV as s a bolus during both study PET/CT scans.
Study NCT05528848 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naloxone
Description: Non-selective opioid antagonist injected by IV parenterally during the second study PET/CT scan only.
Study NCT05528848 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Loperamide Hydrochloride
Description: Loperamide is an FDA- approved, over-the-counter drug for the control and symptomatic relief of acute or chronic diarrhea given orally prior to the optional HC third PET/CT scan only.
Study NCT05357495 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Affective Posner fMRI frustration induction task
Description: During the frustration induction paradigm, children play a game with monetary reward. The game is rigged, thus inducing frustration. The control task does not have any reward component. All participants complete both the control task scanning session and the frustration induction scanning session.
Study NCT05802355 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Diaphragm Release
Description: The participant was supine, with his or her limbs relaxed. With the therapist's forearms aligned toward the participant's shoulders, the therapist gradually increased the depth of contact inside the costal margin during the subsequent respiratory cycles.
Study NCT05802355 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: control group
Description: Respiratory re-training was given to participants in control group in form of slow and deep diaphragmatic breathing, exhalation through the nose with pursed lips (the participants were trained to emphasis on expiratory pressure against pursed lips), Breathing control and breathing-hold exercises, and Relaxation techniques:
Study NCT04841265 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: The intervention arm will receive 400 IU vitamin D3 from routine antenatal multivitamin supplement tablet + 400 IU vitamin D3 daily until delivery.
Study NCT04674956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: PD-1 antibody（Camrelizumab）, 200mg, D1; every 21 days as a cycle.
Study NCT04674956 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Paclitaxel(Albumin Bound) and Gemcitabine
Description: Paclitaxel(Albumin Bound), 125 mg/m2D18; Gemcitabine, 1000mg/m2D1, 8;every 21 days as a cycle.
Study NCT04674956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel(Albumin Bound) and Gemcitabine
Description: Paclitaxel(Albumin Bound), 125 mg/m2D18; Gemcitabine, 1000mg/m2D1, 8;every 21 days as a cycle.
Study NCT04674956 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo, 200mg, D1; every 21 days as a cycle.
Study NCT05389267 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Kinezodianone R hydrochloride
Description: Eyedrops
Study NCT05389267 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05944432 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: FreeStyle Libre 3 Continuous Glucose Monitoring System.
Description: Subjects will be randomised to use the FreeStyle Libre 3 system
Study NCT05944432 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Self monitoring of blood glucose
Description: Subjects will be randomised to continue with their current glucose monitoring system
Study NCT05073315 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adalimumab
Description: Participants will receive subcutaneous (SC) injection of adalimumab
Study NCT05073315 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adalimumab
Description: Participants will receive subcutaneous (SC) injection of adalimumab
Study NCT05073315 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABP 501
Description: Participants will receive SC injection of ABP 501
Study NCT05559827 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isatuximab
Description: Isatuximab treatment at a dose of 10 mg/kg by intravenous route. The first injection of isatuximab will be performed at randomization (month 6 +/- 2 days). A second injection may be performed at day 15 if the reticulocytes \<10 G / L, and a third at day 29 if reticulocytes \<10 G / L. Patients will be assessed on day 1, day 15, day 29, day 45, 2 months, 3 months, 6 months and 9 months after randomization.
Study NCT05131061 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 68Ga-Pentixafor PET/CT imaging
Description: 68Ga-Pentixafor PET/CT imaging
Study NCT04702646 — intervention group
Intervention type: DRUG
Intervention: Bowel preparation before colonoscopy
Description: one day liquid diet will be administered to every patient included in the study and: split-dose bowel preparation with 4 Liters of Polyethylene glycol solution, 2 Liters of PEG-Ascorbic acid or 2 Liters Picosulfate.
Study NCT04702646 — intervention group
Intervention type: PROCEDURE
Intervention: Colonoscopy
Description: colonoscopy will be performed to every patient included in the study
Study NCT04682470 — intervention group
Intervention type: OTHER
Intervention: No intervention ; observational
Description: No intervention; observational
Study NCT05868850 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: auricular point sticking
Description: 1. Acupoint selection: Select Shenmen, spleen, stomach, liver, sympathetic, tongue, digestive system under the cortex, three focal, ear-back spleen.~2. Operation: Use 75% ethanol to disinfect auricular broad skin; To be dry, use tweezers to pick up the middle of the small square tape stuck with Wang do not line seeds, align the indentation and stick well, press gently with the finger abdomen, the strength to the patient feel acid swelling, pain and heat sense and can tolerate it.~3. Press frequency and course of treatment: it is asked to press 4 times a day, once in the morning, middle and evening before going to bed, 3-5 minutes each time, the duration of hospitalization for patients with chemotherapy is generally 3-5 days, intervention begins on the first day of chemotherapy medication, the day of discharge for patients to replace the other side of the ear acupoint, removed after 4 days of discharge. A total of 2 chemotherapy courses were treated.
Study NCT05788679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Azacitidine
Study NCT05262101 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2858 injection
Description: TQB2858 is a dual-function fusion protein that is aProgrammed cell death 1 ligand 1 (PD-L1)/transforming growth factor-β(TGF-β) double antibody.
Study NCT05692440 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Intracept Procedure
Description: Intraosseous radiofrequency ablation of the basivertebral nerve
Study NCT05714761 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Dexcom glucose sensor
Description: Use of a Dexcom G6 Pro
Study NCT05605990 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Innovative tourniquet (Acusense Nonpneumatic tourniquet)
Description: To use this innovative tourniquet before collecting blood samples, and setting IV catheter. We also use this innovative tourniquet to occlude the flow of blood.
Study NCT04716543 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ILI and COVID-19 detection
Description: All participants presenting with ILI symptoms will have non-invasive exam for SARS-CoV-2 detection (nasal, throat, swab, saliva) and a questionnaire.~All family members more than 6 months living with SARS-CoV-2 positive individuals will have will have non-invasive exam for SARS-CoV-2 detection (nasal, throat, swab, saliva) and a questionnaire.
Study NCT05295589 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT scan
Study NCT05295589 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT scan
Study NCT05295589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib Hydrochloride
Description: Given IV
Study NCT05295589 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05295589 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05295589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Given PO
Study NCT05295589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel
Description: Given IV
Study NCT05295589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
Description: Given IV
Study NCT05295589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topotecan Hydrochloride
Description: Given IV
Study NCT05595434 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acute Maastricht Stress Test (MAST), active condition.
Description: The MAST is a standardized stress protocol combining a 5 min preparation phase and 10 min acute stress phase. The last phase is composed by an alternation of physical and psychosocial stressors. In the active condition, participants have to switch between immersion of the hand into cold water and complex mental arithmetic operations.
Study NCT05595434 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Acute Maastricht Stress Test (MAST), placebo condition
Description: The MAST is a standardized stress protocol combining a 5 min preparation phase and 10 min acute stress phase. The last phase is composed by an alternation of physical and psychosocial stressors. In the placebo condition, participants have to switch between immersion of the hand into tempered water and simple mental arithmetic counts.
Study NCT06475976 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Chest computed tomography (CT) with angiography
Description: A CT scan uses a doughnut-shaped machine to take x-rays in a circle around the body. CT scans help doctors learn about the structure of the lungs, heart, and blood vessels in the chest. A CT scan provides more information than regular x-rays. CT w/angiography - injection of intravenous contrast during the CT to image the blood vessels within the chest.
Study NCT06475976 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoscopy with bronchoalveolar lavage
Description: During a bronchoscopy, a lung doctor inserts a small flexible camera into the breathing tube and main branches of the airways within the lungs. During the test, a small amount of sterile fluid is placed into the lung and then retrieved (lavage). This fluid is tested for evidence of infection.
Study NCT06475976 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography
Description: An echo uses sound waves to create computer pictures of the heart.
Study NCT06475976 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 24 hour esophageal pH (potential of hydrogen) - multichannel intraluminal impedance (MII) monitoring (reflux testing)
Description: 24 hour pH/MII testing is used to measure gastroesophageal reflux. A small feeding tube like catheter is passed through the nose or mouth into the esophagus. The catheter is used to measure the frequency and acidity of reflux episodes during a 24 hour monitoring period.
Study NCT05545150 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraoperative Imaging
Description: Clarix Imaging Volumetric Specimen Imager
Study NCT05545150 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lumpectomy
Description: Per standard of care (SOC)
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture Therapy
Description: Undergo acupuncture therapy
Study NCT06063603 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cancer Pain Management
Description: Receive pain clinic referral
Study NCT06063603 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavior Therapy
Description: Undergo CBT
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Discussion
Description: Participate in focus group
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Intervention
Description: Receive self-guided pain management education materials
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participate in exercise
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Complete interview
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interview
Description: Complete interview
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Massage Therapy
Description: Receive massage
Study NCT06063603 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Relaxation
Description: Practice mindfulness
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pain Therapy
Description: Receive pain treatment/medicine
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Palliative Therapy
Description: Receive palliative care referral
Study NCT06063603 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Navigation
Description: Undergo visits with PCM and CHW for pain management
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Referral
Description: Receive pain management referrals
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spiritual Therapy
Description: Receive spiritual support
Study NCT06063603 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spiritual Care Referral
Description: Receive spiritual care referral
Study NCT06063603 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT05216744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ceftriaxone 1000mg + doxycycline 100 mg
Description: Study comparing the effectiveness of two combination regimens in the treatment of gonorrhea and chlamydia, including regimen A (100mg doxycycline orally twice a day for 7 days + 1 dose of 1000mg ceftriaxone intravenously) and regimen B (100mg doxycycline). orally for 7 days + 1 oral dose of 800mg cefixime)
Study NCT05216744 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cefixime 800mg + doxycycline 100 mg
Description: Study comparing the effectiveness of two combination regimens in the treatment of gonorrhea and chlamydia, including regimen A (100mg doxycycline orally twice a day for 7 days + 1 dose of 1000mg ceftriaxone intravenously) and regimen B (100mg doxycycline). orally for 7 days + 1 oral dose of 800mg cefixime)
Study NCT04633044 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Betaine
Description: The intervention with supplement will start during the first 48h after birth and will last for 12 weeks
Study NCT04633044 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The intervention with supplement will start during the first 48h after birth and will last for 12 weeks
Study NCT05279573 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Omega-3 and/or botanical ingredient
Description: Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.
Study NCT05279573 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control product consumption
Description: Product with identical characteristics to the experimental product. Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.