AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06340217 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: washed microbiota transplantation
Description: Washed microbiota transplantation refers to the infusion of washed microbiota from healthy donor into patients' gastrointestinal tract. Participants will receive two doses of WMT for DGP.
Study NCT06340217 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: A carrier fluid with matching volume and consistent appearance to the infusion of washed microbiota.
Study NCT04810780 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DUO Extended Set
Description: to evaluate saftey and efficacy of DUO extended set combined with glucose sensor
Study NCT04152993 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NeuroPace® RNS® System
Description: In this intervention, patients suffering from PTSD undergo a surgical procedure to implant the responsive neurostimulation device (RNS, NeuroPace). This procedure involves the placement of a depth lead bilaterally in the amygdala and hippocampus following a trans-occipital trajectory. The two leads are then connected to a pulse generator fixated to the skull. RNS is able to detect specific signals from the target and to respond with a programmed electrical stimulation. One month after the implantation of the system, the patients will undergo 3 tasks: a fear conditioning task, the international affective picture system and the subsequent memory recall paradigm. These tasks will yield electrophysiological biomarkers of arousal and re-experiencing. We will then program RNS to detect and respond to those biomarkers. The patients will be followed longitudinally for improvement and evidence of target engagement as seen on cerebral metabolism and global electroencephalography.
Study NCT05408793 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Pulse Stimulation
Description: A total of 36 participants (both TPS group and the sham-control group) will receive six 30 minute-TPS sessions (800 pulse in each session, total: 4800 pulse) in 2 weeks' time (i.e., 3 sessions (Monday, Wednesday, Friday) per week, total: 3 hours), on a 1: 1 allocation ratio. Participants will be followed up immediately after the post-stimulation and at 1-month and 3-month period after the intervention. A 2-week TPS intervention alongside with 3-month follow-up is sufficient enough to test the effects of TPS on autism symptoms.
Study NCT05408793 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Pulse Stimulation
Description: A total of 36 participants (both TPS group and the sham-control group) will receive six 30 minute-TPS sessions (800 pulse in each session, total: 4800 pulse) in 2 weeks' time (i.e., 3 sessions (Monday, Wednesday, Friday) per week, total: 3 hours), on a 1: 1 allocation ratio. Participants will be followed up immediately after the post-stimulation and at 1-month and 3-month period after the intervention. A 2-week TPS intervention alongside with 3-month follow-up is sufficient enough to test the effects of TPS on autism symptoms.
Study NCT05873881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thiamine Mononitrate 300 mg
Description: Thiamine Mononitrate 300 mg daily
Study NCT05389852 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dexmedetomidine
Description: After completion of supraclavicular brachial plexus block patients will receive intravenous dexmedetomidine 1 mcg/kg
Study NCT05389852 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: After completion of supraclavicular brachial plexus block patients will receive intravenous dexmedetomidine 1 mcg/kg
Study NCT04882969 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fractionated Thulium laser
Description: LaseMD Lutronic Laser is a 1927-nm fractionated thulium laser, which is better absorbed by water than non-ablative 1,540-nm erbium glass laser energy. The laser energy and power can be customized to target a specific penetration depth and achieve selective photothermolysis in skin while mitigating injury to surrounding tissue. The thermal energy generated by the laser has been shown to facilitate the delivery of kerafactor, which contain hair growth factors to stimulate follicular progenitor cell proliferation and differentiation into follicular keratinocytes to promote hair growth.
Study NCT06213428 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Progressive Perfect Probiotic
Description: Participants will be administered an active probiotic for 28 days. Participants will be blinded as to what intervention they are experiencing.
Study NCT06213428 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be administered a placebo for 28 days. Participants will be blinded as to what intervention they are experiencing.
Study NCT05562401 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Coconut Water
Description: Coconut water is the clear fluid inside the coconut, has natural electrolytes such as potassium, sodium and manganese.
Study NCT05562401 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sport Drink
Description: A type to sport drink is isotonic drink. Is an industrialized drink that containing water, carbohydrates, and 4-8% electrolytes.
Study NCT04838808 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rivaroxaban 2.5 MG [Xarelto]
Description: Rivaroxaban 2.5mg twice daily for 90-days
Study NCT04838808 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablet twice daily for 90-days
Study NCT06065098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evidence-based interventions recommended by the 2019 ACC/AHA Guideline on the Primary Prevention of CVD
Description: The recommended evidence-based interventions include therapeutic lifestyle change and medical treatment of hypertension, diabetes, and hypercholesterolemia.
Study NCT05328947 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Functional Reach and Functional Reach
Description: Establishment of Modified Functional Reach Test (mFRT) and Function Reach Test (FRT) values for individuals with no functional impairments.
Study NCT05948215 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Jing Si Herbal Tea Liquid Packet
Description: The preliminary data demonstrated that the Jing Si Herbal Tea Liquid Packet may improve gastrointestinal symptoms and anxiety in patients with Coronavirus disease 2019(COVID-19). Therefore,this study aims to investigate the impact of the Jing Si Herbal Tea Liquid Packet on psychophysical burden and metabolites of microbiota in patients with FD through a double-blind randomized manner.
Study NCT05948215 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Jing Si Herbal Tea Liquid Packet Placebo
Description: Compared with the improvement effect of Jing Si Herbal Tea Liquid Packet, to avoid participants thinking that the improvement is due to psychological effects.
Study NCT04758962 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1 µg CoV2 SAM (LNP)
Description: 2 doses of 1 µg CoV2 SAM (LNP) vaccine in 0,1-month schedule, administered IM in the deltoid of the non-dominant arm.
Study NCT04798287 — intervention group
Intervention type: DRUG
Intervention: Tofacitinib
Description: First eligible prescription for treating rheumatoid arthritis (RA)
Study NCT04798287 — intervention group
Intervention type: DRUG
Intervention: TNF Inhibitor
Description: First eligible prescription for treating rheumatoid arthritis (RA)
Study NCT05387499 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP-011 (Single Ascending Dose Phase)
Description: The participants will receive assigned single dose of NP-011 after a minimum 8 hour fast on Day 1
Study NCT05387499 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NP-011 (Multiple Ascending Dose Phase)
Description: The participants will receive assigned dose of NP-011 after a minimum 8 hour fast once daily for 7 days
Study NCT05387499 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: NP-011 (Placebo)
Description: The participants will receive single dose of NP-011 after a minimum 8 hour fast on Day 1 in Single Ascending Dose part and will receive once daily for 7 days after a minimum 8 hour fast in Multiple Ascending dose part of the study
Study NCT05024292 — intervention group
Intervention type: PROCEDURE
Intervention: rapid local ischemic postconditioning (RL-IPostC)
Description: with 5 circules of balloon inflations in the ipsilateral internal carotid artery, each circulation includes inflation lasting 15 seconds followed by 15 seconds of deflation
Study NCT06261281 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation therapy
Description: Including:Acupuncture: Regular acupuncture treatment that can prevent muscle atrophy, improve circulation, and have a stimulating effect. Exercise therapy: Training that focused on limb movements or joint mobilization to prevent muscle contracture, reduce joint mobility, improve spasms, and promote blood circulation. Others: Regular turning, back patting, and position changes performed by caregivers.
Study NCT06261281 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: Including:Acupuncture: Regular acupuncture treatment that can prevent muscle atrophy, improve circulation, and have a stimulating effect. Exercise therapy: Training that focused on limb movements or joint mobilization to prevent muscle contracture, reduce joint mobility, improve spasms, and promote blood circulation. Others: Regular turning, back patting, and position changes performed by caregivers.
Study NCT06261281 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intermittent Oro-esophageal Tube Feeding
Description: Based on this, the patients in the observation group were given nutrition support with Intermittent Oro-esophageal Tube Feeding (Medical Device No. 20010234, developed by the Swallowing Disorders Research Institute of Zhengzhou University). The entire feeding process strictly followed the standard procedure of Intermittent Oro-esophageal Tube Feeding. During the feeding process, patients were maintained in a semi-recumbent position with their head elevated, facilitating the placement of the tube into the oral cavity along one side, with the chin brought close to the manubrium sterni.
Study NCT06261281 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nasogastric tube feeding
Description: The patients in the control group were provided nutrition support with Nasogastric tube feeding, while the feeding process strictly followed the relevant guideline. During the treatment, the patients remained in a continuous state of tube indwelling, receiving feeding every 2-3 hours with a maximum feeding volume of 200ml, of which the contents were consistent with the observation group. The entire feeding process was conducted by trained nursing staff. Besides, the tube was replaced by a new one every 5-7 days.
Study NCT06164821 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: luspatercept
Description: Adult patients with TD thalassemia were given luspatercept subcutaneous injection.
Study NCT04908943 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RENEW
Description: RENEW is a 12-week, peer-led, web-based program to help people with scleroderma learn skills that can be used to manage disease symptoms and improve well-being.
Study NCT05535205 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Digital preoperative assessment
Description: a digital preoperative assessment for patient requiring surgery
Study NCT05535205 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Face-to-face preoperative assessment
Description: a face-to-face preoperative assessment for patient requiring surgery
Study NCT04879147 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Evalution of thyroid function
Description: Determination of TSH, free T4, free T3, SPINA-GT, SPINA-GD and Jostel's TSH index
Study NCT06129513 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bilateral resistance exercise
Description: A bout of bilateral resistance exercise consisting of barbell back squat, leg leg press and leg extension
Study NCT06129513 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Bilateral resistance exercise
Description: A bout of bilateral resistance exercise consisting of barbell back squat, leg leg press and leg extension
Study NCT06129513 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Whey protein
Description: Following execution of bilateral resistance exercise, participants will ingest 32 g protein from whey protein isolate
Study NCT06129513 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Plant-blend protein
Description: Following execution of bilateral resistance exercise, participants will ingest 32 g protein from plant-blend protein isolate
Study NCT06080724 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone
Description: already described
Study NCT02254915 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Synergo + MMC
Description: Synergo radiofrequency (RF)-Induced hyperthermia-chemotherapy with mitomycin C (RITE). Intravesical instillation of MMC utilizing the Synergo system.
Study NCT02254915 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bacillus Calmette-Guérin
Description: Intravesical instillation of BCG.
Study NCT04880005 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinical decision support
Description: Based on the phenotyping and algorithms developed by the hospital specialists at Odense University Hospital and Holbæk Hospital in collaboration with GPs, the individual GPs and their patients will receive individualized recommendations on lifestyle interventions and pharmacological treatments.~The GPs will receive specific clinical decision support (CDS) recommendations on what drugs to prescribe to each patient based on the phenotyping in accordance with a clinical decision support tool (Cambio) and the updated guidelines at all times (Sparrow 2019). The treatment advice to the GPs will be adjusted annually based on treatment effect, re-phenotyping, and updated knowledge of the treatment of T2D. Furthermore, psychiatric, socioeconomic and/or cultural challenges and other determinants for frailty will be a part of the individualized intervention provided to patients by the GPs, again based on the specialist advice.
Study NCT04880005 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Lifestyle Coaching
Description: As part of DICTA, the patients are offered a personal health coach (dietician, nurse, occupational therapist, or physiotherapist) through the complex eHealth intervention (Liva). Patients will receive personalized empathic, relation driven coaching on healthy lifestyle on the individual patient's preferences (e.g. increased physical activity, healthier diet, weight loss, smoking cessation, personal goal setting, tailored information, peer to peer support), including optimal pharmacological treatment (Komkova 2019). The collaborative eHealth tool will give health coaches access to patient registered outcome measurements (PRO), information. This forms the basis of the individual coaching and is partly supported by artificial intelligence (AI) to improve the coaching by the health coaches (Holzinger 2016).
Study NCT06517979 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence (AI)-based diagnostic model
Description: Collect pathological slides of resected lymph nodes of the enrolled patients. Digitise these slides into whole-slide images (WSIs). Analyze the WSIs using the AI model to generate diagnostic results (with or without lymphatic metastasis). No intervention to patients would be performed in this diagnostic test study.
Study NCT04880005 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integration to Standard Electronic Health Record
Description: Data on physical activity, steps, diet goal fulfillment, smoking status etc., are being provided for GPs in a web-based solution integrated into the GPs' health record system. Integration with the GP system XMO (covering 52% of all Danish GPs) has been finalized.
Study NCT04937010 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Occipital nerve stimulator implant
Description: Implantation of occipital nerve stimulator and different stimulation parameters
Study NCT04937010 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Occipital nerve stimulator implant
Description: Implantation of occipital nerve stimulator and different stimulation parameters
Study NCT05123560 — intervention group
Intervention type: OTHER
Intervention: Anonymous online questionnaire
Description: A QR code qill be provided to access the online questionnaire
Study NCT04671472 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NPC-09
Description: The drug will be administered by the oral route with the same manner
Study NCT04671472 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: NPC-09 placebo
Description: The drug will be administered by the oral route with the same manner
Study NCT05598658 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Remote ischemic conditioning
Description: Remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 200 mm Hg.
Study NCT05598658 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Sham remote ischemic conditioning
Description: Sham remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of healthy upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 60 mm Hg.
Study NCT05833594 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs
Description: The Experimental group received a combination of omega-3 fatty acids, and glutamine, whereas the control group received standard formula.
Study NCT05828641 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Supination-flexion maneuver
Description: In the Supination-flexion group, the forearm will be supinated first, followed by full flexion of the elbow joint (Supination-flexion maneuver).
Study NCT05828641 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hyperpronation maneuver
Description: In the hyperpronation group, the forearm will be pronated with the child's palm facing down (hyperpronation maneuver).
Study NCT04792502 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mosunetuzumab
Description: Administered subcutaneously by injection beginning with 5 mg and increasing to 45 mg.
Study NCT04792502 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Patients in the augmentation cohort will be dosed continuously, 10 mg orally once daily, with or without food.
Study NCT05726214 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: The face-to-face multicomponent program entailed:~* Strength training of upper and lower limbs. Familiarization phase included 2-3 exercises of 1-2 series and 8-12 repetitions per session. During the acquisition phase, 2-3 exercises of 2-3 series and 8-12 repetitions at a higher velocity. The resting time between sets lasted 1-3 minutes.~* Balance exercises included proprioception, agility and weight transfer exercises. Difficulty progressively increased by reducing the base of support, by including multidirectional displacements, walking on tiptoe or heels, body-weight transfer, dynamic exercises modifying the centre of gravity, and stressing postural muscles and by sensorial reductions.~* Flexibility exercises: Static stretching maintained during 20-30s carried out at the end of each session.~The Vivifrail exercise wheel corresponding to each participant was given according to their functional level type.
Study NCT05726214 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Recommendations for active lifestyle
Description: After the baseline assessments, all participants received individualized counseling for following physically active lifestyle and reducing sedentary behaviors. Participants were encouraged to increase the physical activity time and intensity, and to hourly break the sedentary time while at home. The recommendations were transmitted verbally and through written material.
Study NCT05726214 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Recommendations for active lifestyle
Description: After the baseline assessments, all participants received individualized counseling for following physically active lifestyle and reducing sedentary behaviors. Participants were encouraged to increase the physical activity time and intensity, and to hourly break the sedentary time while at home. The recommendations were transmitted verbally and through written material.
Study NCT04755374 — intervention group
Intervention type: OTHER
Intervention: Discharged ≤ 21 days
Description: Discharged from palliative care unit in equal less than 21 days
Study NCT04755374 — intervention group
Intervention type: OTHER
Intervention: Prolonged discharge
Description: Discharged from palliative care unit in longer than 21 days
Study NCT04928183 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Carbon monoxide rebreathe
Description: Carbon monoxide exposure to increase blood (Carboxyhemoglobin) COHb safely to \~10%
Study NCT04928183 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Nitroprusside
Description: Bolus Sodium Nitroprusside (SNP) injection for endothelium-independent vasodilation measure
Study NCT04928183 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Sodium Nitroprusside
Description: Bolus Sodium Nitroprusside (SNP) injection for endothelium-independent vasodilation measure
Study NCT04928183 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phenylephrine Hydrochloride
Description: Bolus Phenylephrine injection for observe α1-mediated vasoconstriction during mild exercise