AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05114122 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vonlay Ceramic restorations
Description: vonlay is a hybrid of an onlay with an extended buccal veneer surface for use in bicuspid regions where there is mostly enamel to bond to. The vonlay is less invasive, more readily repairable, less technique-sensitive to attain adequate bonding, and will leave sounder tooth structure remaining if further treatment is required in the future
Study NCT05114122 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Onlay Ceramic restorations
Description: Onlays are used to restore large areas of decay and also used to replace old restorations, whether they are defective amalgam fillings, old cast-gold onlays, or fabricated from some other material
Study NCT05622266 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulpotomy
Description: The patients who are randomly assigned to the experimental group receive pulpotomy.
Study NCT05622266 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Root Canal Therapy
Description: The patients who are randomly assigned to the Active Comparator group receive root canal therapy.
Study NCT06507501 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Load Blood Flow Restriction Exercise Training (LL-BFRE)
Description: Blood Flow Restriction exercise training, also known as occlusion training or KAATSU training, is a contemporary exercise training method based on partially restricting arterial and venous blood flow for short periods.
Study NCT06507501 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Load Resistive Exercise Training (HL-RE)
Description: HL-RE is a conventional, well known exercise method to enhance muscle strength and improve physical performance. It's performed by using resistance bands or weights applying on the extremity.
Study NCT05104619 — intervention group
Intervention type: PROCEDURE
Intervention: tongue surgery
Description: In squamous cell carcinoma of the tongue, complete surgical resection of the tumor
Study NCT06036329 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group A : provided with 1 Whitsundays Nasal mask without a spare mask cushion
Description: Group A will be provided with 1 Whitsundays Nasal mask without a spare mask cushion (replacement cushions will only be provided when requested)
Study NCT06036329 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Group B : provided with 1 Whitsundays Nasal mask with 2 spare mask cushions
Description: Group B will be provided with 1 Whitsundays Nasal mask with 2 spare mask cushions
Study NCT05332249 — intervention group
Intervention type: PROCEDURE
Intervention: Surgery
Description: Patients who undergo spinal surgery for degenerative spinal disease
Study NCT05482581 — intervention group
Intervention type: OTHER
Intervention: Questionnaires set
Description: Participants will be asked to respond to the demographic information sheet,e-cigarette using characteristics sheet,awareness of e-cigarettes sheet;,willingness to use e-cigarettes sheet, knowledge, attitudes and cognitions related to e-cigarettes sheet, awareness of new regulations on e-cigarette control sheet.
Study NCT05879367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level 1)
Description: Eflornithine 2.3 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule
Study NCT05879367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level 2)
Description: Eflornithine 2.8 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule
Study NCT05879367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eflornithine (Dose Level -1)
Description: Eflornithine 1.75 g/m2 administered orally every 8 hours on a 2 weeks on, 2 weeks off schedule
Study NCT05879367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Temozolomide 150 mg/m2 (with option to escalate per USPI maintenance phase instructions) administered orally once daily on a 5 days on, 23 days off schedule
Study NCT05615194 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: 0.6 mcg/kg in infusion over 10 minutes
Study NCT05615194 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Volume equivalent in infusion over 10 minutes
Study NCT05483166 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ImPACT
Description: During the ImPACT program, the childhood cancer survivor and at least one parent collaborates on:~1. Becoming aware of the child's core strengths and difficulties~2. Helping the child to be optimally responsive to the guidance of the parent(s), and~3. Creating compensatory strategies to respond to real-world manifestations of the child's difficulties and helping the child implement these strategies at home.
Study NCT06277232 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Nutrition care
Description: Nutrition care is designed to include nutrition assessment (e.g., malnutrition screening, monitoring weight changes, etc.), optimization of individual dietary patterns, and evaluation. Through the Diet4painrelief platform, a dietician will follow up the progress of each participant in different timepoints and also plan meetings with other professionals in IPRP. A dietitian together with a physician in rehabilitation are responsible for the administration of the procedure.
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Dialogue and education (part of Interdisciplinary Pain Rehabilitation Program)
Description: Dialogue and education consists of patient education, training in wellness and healthy living habits, meetings with families, video feedback, and couples therapy and self-training (e.g., home lessons, activity diary, physical self-training, reflection time, and self-analysis. . In addition, lectures in basic pain science and pain management are offered for both patients as well as for relatives, friends, and colleagues.
Study NCT06103318 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ICOgnition
Description: The ICOgnition intervention for breast cancer patients consists of three levels:~Level 1: Monthly assessments using FACT-Cog PCI and Cognifit. Scores \<54 (PCI) or ≤250 (Cognifit) escalate to Level 2.~Level 2: Specialized content includes Cognitive Psychoeducation, validating experiences and improving health literacy; Behavioral Guidance, offering practical strategies for daily tasks; and Embracing Cognitive Deficits, promoting self-compassion and acceptance through mindfulness and metaphors.~Level 3: Online cognitive training focuses on enhancing cognitive skills through gaming exercises, completing the comprehensive intervention approach.
Study NCT06103318 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ICOgnition
Description: The ICOgnition intervention for breast cancer patients consists of three levels:~Level 1: Monthly assessments using FACT-Cog PCI and Cognifit. Scores \<54 (PCI) or ≤250 (Cognifit) escalate to Level 2.~Level 2: Specialized content includes Cognitive Psychoeducation, validating experiences and improving health literacy; Behavioral Guidance, offering practical strategies for daily tasks; and Embracing Cognitive Deficits, promoting self-compassion and acceptance through mindfulness and metaphors.~Level 3: Online cognitive training focuses on enhancing cognitive skills through gaming exercises, completing the comprehensive intervention approach.
Study NCT05214391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanubrutinib
Description: The initial dose is 80mg/day. If the treatment is ineffective after 4 weeks, and under the condition of good safety, the investigator will judge that the dosage should be added to 80mg twice/day，or a higher dose for oral maintenance. The maximum dose is 160mg twice a day. The duration of zanubrutinib is 24 weeks.~In case of intolerable adverse reactions, such as severe infection, severe bleeding, hematopenia, arrhythmia, etc., investigator can reduce the dose of zanubrutinib, or withdraw from clinical trials as appropriate.
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: activity training (part of Interdisciplinary Pain Rehabilitation Program)
Description: Activity training includes graded activity training, and exposure training, which are delivered by an interdisciplinary team (i.e., a physiotherapist, an occupational therapist, and a psychologist).
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: meetings (part of Interdisciplinary Pain Rehabilitation Program)
Description: The meetings consist of conferences with patients, rehabilitation team, vocational guidance, rehabilitation coordinator, goal-setting meetings, and meetings to check goal achievement.
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Cognitive behavioral therapy (part of Interdisciplinary Pain Rehabilitation Program)
Description: Acceptance and Commitment Therapy (ACT, e.g., goal compass, training in ACT principles, and mindfulness) is mainly delivered by psychologist in a group-treatment (e.g., training in coping strategies). The cognitive behavioral principles are also used in physiotherapy, ergonomics, and education in pain management.
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Relaxation techniques (part of Interdisciplinary Pain Rehabilitation Program)
Description: This group-treatment is mainly format by a physiotherapist and psychologist in an interdisciplinary team.
Study NCT06277232 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Physical exercise (part of Interdisciplinary Pain Rehabilitation Program)
Description: This group-treatment is mainly format by a physiotherapist in an interdisciplinary team.
Study NCT05148416 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: High intensity laser treatment
Description: 20 patients received high power laser therapy . Zimmer High power laser applied by laser probe perpendicular to and in slight contact with the skin around knee joint , the total energy was delivered to the patient during one session was 1060 j in 3 phases of treatment.
Study NCT05148416 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham HILT.
Description: 20 patients received placebo laser  sham laser . The same treatment protocol of HILT was given to the sham group, but the laser instrument was switched off during applications. All laser applications were performed by the same physiotherapist.
Study NCT05148416 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: knee osteoarthritis conventional exercises program
Description: knee osteoarthritis conventional exercises program in form of stretching exercises for both vastus medialis and gastrocnemius muscles , ROM exercises for knee flexion and extension , and isometric strengthening exercise of previously mentioned muscles .~all interventions were done under the supervision of physiotherapist for 30 minutes once a day for 3 days per week during a period of 4 weeks.
Study NCT05148416 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: knee osteoarthritis conventional exercises program
Description: knee osteoarthritis conventional exercises program in form of stretching exercises for both vastus medialis and gastrocnemius muscles , ROM exercises for knee flexion and extension , and isometric strengthening exercise of previously mentioned muscles .~all interventions were done under the supervision of physiotherapist for 30 minutes once a day for 3 days per week during a period of 4 weeks.
Study NCT06461052 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: music therapy
Description: The patient will benefit from viewing the video and the music therapy session in the waiting room of the operating room. The patient will be asked again for their anxiety score using an anxiety scale. This will define the main outcome of the study. Following this collection and in order not to influence the response, investigators will collect from the patient his compliance with the two proposed techniques as well as his appreciation of the tool.
Study NCT06294964 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sleep education, behavioral education
Description: Provide health education materials which covering sleep education, behavioral education, chronic diseases such as cardiovascular diseases. Topics touch on such as why you need healthy sleep? What methods can be used to regulate insomnia, and how to regulate sleep breathing problems? How do the elderly maintain a good sleep? What are the risk factors for cardiovascular and cerebrovascular diseases? How to reduce the risk of developing sleep disorders or chronic diseases through changing everyday life?
Study NCT05927259 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: n acetyl cysteine
Description: A patients received NAC 140 mg/Kg IV infusion (as a loading dose), then 70 mg/KgIV infusion every 4 hours up to 17 doses
Study NCT05927259 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: standard treatment
Description: stabilization and antidotes
Study NCT05927259 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard treatment
Description: stabilization and antidotes
Study NCT04905095 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EWS
Description: Early Warning Score will be implemented in the computer system of the nursing station which belong to this intervention group. When the nurses enter the vital signs of the patients into the system, the EWS will be automatically calculated and an alarm will be displayed if an intervention is necessary, which is protocolized.
Study NCT04905095 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: usual clinical care
Description: Nurses perform their clinical monitoring activities as usual. EWS will not be implemented in their nursing station
Study NCT06600269 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cycling Training
Description: Cycling combined with priming strategies to enhance motor learning tasks. Each session will last for 15 minutes, conducted three times per week, over a period of two weeks.
Study NCT05775315 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Action Observation Therapy
Description: Exercises of AO protocol MOVEMENT TOTAL VIDEO TIME PATIENT TIME Upright the pelvis 1 minute 5 minutes Move weight forward 1 minute 5 minutes Move weight to the left and right 1 minute 5 minutes Rotate right and left 1 minute 5 minutes Upright the pelvis in sitting position 1 minute 5 minutes Move weight forward from a sitting position 1 minute 5 minutes Stand up from a sitting position 1 minute 5 minutes Move weight right and left 1 minute 5 minutes Forward weight shift with right foot and left foot 1 minute 5 minutes Walking sideways to left 1 minute 5 minutes Walking sideways to right 1 minute 5 minutes~Rest time between watching and performing each video will be 1 minute. the exercises will be done 3 times a week.
Study NCT05775315 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Action Observation Therapy along with visual feedback
Description: Exercises of AO protocol in front of a mirror MOVEMENT TOTAL VIDEO TIME PATIENT TIME Upright the pelvis 1 minute 5 minutes Move weight forward 1 minute 5 minutes Move weight to the left and right 1 minute 5 minutes Rotate right and left 1 minute 5 minutes Upright the pelvis in sitting position 1 minute 5 minutes Move weight forward from a sitting position 1 minute 5 minutes Stand up from a sitting position 1 minute 5 minutes Move weight right and left 1 minute 5 minutes Forward weight shift with right foot and left foot 1 minute 5 minutes Walking sideways to left 1 minute 5 minutes Walking sideways to right 1 minute 5 minutes~Rest time between watching and performing each video will be 1 minute. the exercises will be done 3 times a week.
Study NCT05507515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONO-2020
Description: ONO-2020 tablets
Study NCT04953221 — intervention group
Intervention type: DRUG
Intervention: YJ001
Description: Skin spray
Study NCT05710549 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high-density electroencephalography (hdEEG)
Description: EEG will be recorded with a 257-channel EEG system (Geodesic Sensor Net, MegStim). An EEG net is applied at once on the head with evenly spaced sensors that provide full scalp coverage, including the cheek, Ag/Ag-Cl electrodes that are interconnected by thin rubber bands and contain small sponges soaked with saline water that touches the participant's scalp surface directly. Net application takes about 10 min to derive impedances to \<30 kOhms. EEG is recorded with 1 kHz and band-pass filtered between 0.1-200 Hz. Vertex electrode Cz is used as an acquisition reference.
Study NCT05710549 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial alternating current stimulation (tACS)
Description: tACS will be delivered by a battery-driven current stimulator Starstim SS32 (Neuroelectrics) through surface Ag/AgCl electrodes placed into holes of a neoprene cap corresponding to the international 10/20 EEG system. Gel (Parker Lab, Inc.) will be applied to optimize signal conductivity and lower impedance.
Study NCT05589337 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Baduanjin
Description: The Baduanjin training program consisted of two 90-min training classes and at least five 30-min at-home practice sessions per week for 16-weeks. All sessions included 10 min of warmup and 10 min of cooldown.
Study NCT05589337 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health education
Description: Health education is provided by psychologist and TCM doctor, including work, rest, diet and other basic programs.
Study NCT05589337 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health education
Description: Health education is provided by psychologist and TCM doctor, including work, rest, diet and other basic programs.
Study NCT05507515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo tablets matching ONO-2020 tablets
Study NCT05516849 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxandrolone
Description: Oxandrolone is a synthetic anabolic androgenic steroid that induces its responses by binding to androgen receptors which modulates gene expression to increase protein synthesis and efficient utilisation of amino acids. Oxandrolone was first synthesized in 1962 through 17alpha-alkylation of testosterone resulting in a formal composition of (4bS,7S,9aS,9bR,11aS)-tetradecahydro-7-hydroxy-4aS,6aS,7-trimethyl- cyclopentanaphthopyran-2(1H)-one and molecular formula of C19H30O3.
Study NCT05516849 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: As there is currently no approved medication to aid in soft-tissue regeneration, we will be using a placebo control.
Study NCT05486689 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary Rehabilitation
Description: The enrolled subjects will receivePR program. The 3 weeks inpatient PR will include education, exercise training, nutritional and psychological counselling.~Education: individualized session of 20 minutes each and group session of 45 minutes each. Endurance training: at least twelve 30-minute daily sessions of supervised incremental exercise training according to Maltais, continuous cycling at 50-70% of the maximal load calculated on the basis of the baseline 6MWT according to Hill. Strength training: twelve 30-minute daily sessions of peripheral limb muscle strength training: 2 set of 8 repetitions during the first week, increased at 12 from the second. The initial load will be set at 30/50% of maximal voluntary isometric strength (MVS). Psychological intervention: individual tailored intervention will be offered when the Hospital Anxiety and Depression Scale (HADS) score is >10 or judged necessary by clinicians, after verifying the subject's motivation.
Study NCT04765306 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Direct Fascial Closure
Description: Fascial closure using traditional surgical instruments and suture without laparoscopic guidance.
Study NCT04765306 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fascial Closure Device
Description: Fascial closure using a fascial closure device under direct laparoscopic guidance.
Study NCT05189535 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline
Description: Pentoxifylline 400 mg oral tablet twice daily for 12 weeks.
Study NCT05189535 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Paclitaxel
Description: Paclitaxel I.V 80 mg/m2 weekly
Study NCT05189535 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel I.V 80 mg/m2 weekly
Study NCT05189535 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo
Study NCT05920109 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ESP block
Description: Patients in the experimental group will have a continuous Erector Spinae Plane Block within the first 6 hours post-admission, with a continuous 1ml/h infusion of Ropivacaine (2mg/ml) associated with a 25 ml bolus every 6h. The catheter will be used from the trauma bay to the ICU as long as possible with a dedicated infusion pump (with a bolus mode). In case of accidental catheter removal, a second introduction of ESP block catheter is allowed within the first 24 hours. In case of continuous ESP block failure (incidence \< 5% of the total experimental group), patients will be switched to the control group.
Study NCT05103891 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Binimetinib Oral Tablet
Description: two-period, crossover study
Study NCT05647759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HEART Camp Connect
Description: Once eligible and enrolled, participants will aim to complete 150 minutes of moderate-intensity exercise a week with the help of a virtual exercise coach
Study NCT06269029 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest mobility exercises
Description: exercises were repeated 6 times on each side with rest of period for 30 seconds in between. The intervention will be carried out for one week with total of 7 sessions. Each Exercise will be accompanied by breathing pattern. In neutral position of exercises, subjects will be asked to exhale during flexion, turning or extension subject will be asked to do inhale.