AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03978780 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: 80mm 22G block needle will be inserted using an in-plane cranial to caudad approach, the needle will be advanced to target the interfascial plane deep to the erector spinae muscle at the T2 transverse process. Once the needle tip is in the correct position, 20 ml of the local anaesthetic (ropivacaine 0.5% with 1:400,000 epinephrine) will be administered slowly in 5 ml aliquots under frequent aspiration and correct spread in the interfascial plane will be observed.
Study NCT03978780 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Block
Description: Patients randomised to the Control group will then receive a sham subcutaneous injection of 0.5ml normal saline injected at the same site as the ESP block under ultrasound guidance to stimulate a real block procedure.
Study NCT04832009 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextrose 20 % in 500 ML Injection
Description: Dextrose (20% intravenous solution) will be obtained from the Investigational Pharmacy located in the KU Clinical Research Center where studies take place. After fasting for at least 8 hours, dextrose will be administered via antecubital vein at a standard rate of 4 mg/kg/min for 2 hours.
Study NCT04832009 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intralipid
Description: Intralipid ® 20% will be obtained from the Investigational Pharmacy located in the KU Clinical Research Center where studies take place. After fasting for at least 8 hours, Intralipid ® 20% will be administered via antecubital vein at 0.75 mL/min for 2 hours Increases in circulating markers of oxidative stress peak within 2 hours of Intralipid ® 20% infusion in healthy adults (42). An initial heparin bolus of 1000 UL followed by 200 U/hr infusion will be included to activate endothelial lipoprotein lipase and accelerate hydrolysis of fatty acids.
Study NCT04832009 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Saline
Description: Saline will be obtained from the Investigational Pharmacy located in the KU Clinical Research Center where studies take place. Will be administered via antecubital vein at 75 to 150 mL/hour for 2 hours.
Study NCT04832009 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ascorbic acid
Description: (ASCOR) will be obtained from the KU Investigational Pharmacy located in the KU Clinical Research Center where studies will take place. A priming bolus of 0.06 g ascorbic acid/kg fat free mass (FFM) dissolved in 100 mL of saline will be infused intravenously at 5 mL/min for 20 minutes, followed immediately by a drip-infusion of 0.02 g/kg FFM dissolved in 30 mL of saline administered over 2 hours at 0.5 mL/min. The KU Investigational Pharmacy will randomize ascorbic acid or placebo (saline) for each participant.
Study NCT04820205 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intranasal dexmedetomidine and ketamine
Description: Intranasal administration of dexmedetomidine (2mcg/kg) and ketamine (3mg/kg) to increase the success rate of adequate pediatric procedural sedation (pediatric sedation state scale = 1,2,3)
Study NCT04820205 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral chloral hydrate
Description: Oral chloral hydrate (50mg/kg) administration to induce adequate pediatric procedural sedation (pediatric sedation state scale = 1,2,3)
Study NCT05597150 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Magnesium Citrate
Description: Each participant should receive a high-magnesium diet for 1-3 weeks and take magnesium supplements for 4-6 weeks.
Study NCT06579534 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health education strategy
Description: Based on the concept of precise health care, investigators design risk awareness, self-health management and fall prevention care measures, and provide inpatients with high-risk groups with frailty and falls with health education guidance on muscle endurance training and fall prevention. This study adopts purposive sampling, randomization, assignment, and parallel experiments to divide into a control group and an experimental group. The control group uses conventional health education guidance to provide fall prevention education, and the experimental group uses multimedia health education videos to provide education to patients or primary caregivers. Provide health education on the risk, management and prevention of falls.
Study NCT04942665 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green
Description: Low dose or standard dose ICG will be administered by the anesthesiologist as guided by the study coordinator at the beginning of the case, at two points during the operation (1- prior to the dissection of the biliary tract and 2- upon completion of the dissection and establishment of the critical view of safety).
Study NCT04942665 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Indocyanine green
Description: Low dose or standard dose ICG will be administered by the anesthesiologist as guided by the study coordinator at the beginning of the case, at two points during the operation (1- prior to the dissection of the biliary tract and 2- upon completion of the dissection and establishment of the critical view of safety).
Study NCT04942665 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PINPOINT Endoscopic Fluorescence
Description: The PINPOINT Endoscopic Fluorescence Imaging System (Stryker Corporation, Kalamazoo, Michigan) will be used. This device enables the surgeon to simultaneously see real-time, high-definition visible-range and NIR fluorescence videos and to superimpose them. It is currently approved by the FDA for intraoperative near-infrared fluorescence imaging.
Study NCT04942665 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: PINPOINT Endoscopic Fluorescence
Description: The PINPOINT Endoscopic Fluorescence Imaging System (Stryker Corporation, Kalamazoo, Michigan) will be used. This device enables the surgeon to simultaneously see real-time, high-definition visible-range and NIR fluorescence videos and to superimpose them. It is currently approved by the FDA for intraoperative near-infrared fluorescence imaging.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Actigraphy
Description: Sleep efficiency recording at home by means of actigraphy during 10 consecutive days.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Actigraphy
Description: Sleep efficiency recording at home by means of actigraphy during 10 consecutive days.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Recording of proximal and distal skin temperature and temperature of the bedroom
Description: Recording of proximal and distal skin temperature at home by data loggers placed on the skin during 10 consecutive days.~Recording of temperature of the bedroom by a data logger during 10 consecutive days.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Recording of proximal and distal skin temperature and temperature of the bedroom
Description: Recording of proximal and distal skin temperature at home by data loggers placed on the skin during 10 consecutive days.~Recording of temperature of the bedroom by a data logger during 10 consecutive days.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaires assessing subjective sleep quality
Description: One-off questionnaires assessing subjective sleep quality. The Pittsburgh Sleep Quality Index (PSQI) evaluates sleep quality with questions about sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medications, and daytime dysfunction during the last month.~The Epworth Sleepiness Scale evaluates daytime sleepiness and comprises 8 items (situations) during which individuals assess how likely they would fall asleep.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires assessing subjective sleep quality
Description: One-off questionnaires assessing subjective sleep quality. The Pittsburgh Sleep Quality Index (PSQI) evaluates sleep quality with questions about sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medications, and daytime dysfunction during the last month.~The Epworth Sleepiness Scale evaluates daytime sleepiness and comprises 8 items (situations) during which individuals assess how likely they would fall asleep.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sweat test
Description: One-off measurement of sweating by a sweat test at the hospital.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sweat test
Description: One-off measurement of sweating by a sweat test at the hospital.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Urine melatonin assay
Description: Two urine melatonin at home during 24 hours, one during a week day and one during the weekend
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Urine melatonin assay
Description: Two urine melatonin at home during 24 hours, one during a week day and one during the weekend
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Polysomnography
Description: Sleep architecture assessed by a polysomnography during one night at home.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Polysomnography
Description: Sleep architecture assessed by a polysomnography during one night at home.
Study NCT05378932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standardized psychological and neuropsychological assessment
Description: One-off psychological and neuropsychological assessment of patients with HED during a hospital visit
Study NCT06267950 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: systematic therapy
Description: Both groups were given systematic therapy according to the routine treatment plan for PRS for 4 weeks. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.
Study NCT06267950 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: systematic therapy
Description: Both groups were given systematic therapy according to the routine treatment plan for PRS for 4 weeks. The main intervention measures included: 1) non-invasive ventilator treatment, generally at least once every night and typically not exceeding continuous daily usage.; 2) attention to feeding and sleeping positions, with a recommended sleeping position of lateral recumbent and the head of the bed raised by 20-30°; 3) swallowing function training, such as tongue muscle stretching training, assisted anterior jaw protrusion training, lemon ice stimulation to the soft palate, pharyngeal wall, etc., generally 5 days per week, twice per day, 5-20 minutes each time; 4) pulmonary ultrashort wave therapy, generally at least 2-3 times a week, and not more than once a day; 5) physical therapy, such as intensive training for gross motor functions including lifting the head, turning over, sitting, crawling, standing, etc., generally 3-5 days per week, 1-2 times per day, 5-20 min each time.
Study NCT06267950 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intermittent oro-esophageal tube feeding
Description: The specific procedure was as follows: the infant was placed in a semi-recumbent or sitting position with the head fixed. Before each feeding, the infant's oral and nasal secretions were to be cleared. An intermittent oro-esophageal tube was appropriately lubricated with water on the head part. The professional medical staff held the tube and slowly inserted it through one side of the mouth into the upper part of the esophagus. The depth of insertion depended on the patient's age and height. After each feeding, the tube was immediately removed, and the patient was held upright for at least 30 minutes in case of reflux.
Study NCT06267950 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: gastric tube feeding
Description: In PNG group, disposable gastric tubes were used for feeding to provide nutritional support. Each feeding was administered by a nurse using the infant's mother's breast milk through the tube. The amount of each feeding varied from 20 to 100 ml depending on the age of the infant, with feedings given every 2 to 3 hours, approximately 10 times per day. The duration of each feeding procedure ranged from 10 to 20 minutes. The total daily intake ranged from 200 to 1000 ml. Each tube was kept indwelling for 5 to 7 days. When the tube needed to be replaced, it was removed after the last feeding of a day and a new tube was to be inserted through the other nostril on the following morning to continue the nutritional support.
Study NCT05131815 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
Description: Participants will engage in two to three virtual physical activity sessions a week through the BurnAlong app for three months with a chosen partner and participate at least twice a week in the research team-mediated social media message board. Additionally, participants will be asked to participate in one live physical activity session per month with an exercise physiologist.
Study NCT06188624 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2922 for injection
Description: TQB2922 for injection is administrated to patients with advanced cancers, 28 days as a treatment cycle
Study NCT05544175 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: NEUROMOdulation pain therapy in combination with intensive physiotherapy
Description: Neuromodulation: Spinal cord stimulation affects nerve tissues with a defined electrical current. We will use low-voltage electrical stimulation of the posterior roots of the spinal cord in the MRI region of the localized conus medullaris. Electrodes are inserted epidurally from a laminotomy in the lumbosacral region.~Physiotherapy will be based on recommendations for spinal patients.
Study NCT06216704 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: pQCT
Description: pQCT will be utilized to obtain volumetric BMD (mg/cm3) of the left tibia. Measurements using a Stratec XCT 3000 device (Orthometrix, White Plains, NY) will be obtained at multiple locations, in relation to distal growth plate.
Study NCT05577832 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Helfer Skin Tap Technique
Description: In a single-group design, 3 technique injections will be administered to the patients, to be randomized. The HST technique will be applied to patients in any one of 1days in a randomized fashion.
Study NCT05577832 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ShotBlocker Technique
Description: In a single-group design, 3 technique injections will be administered to the patients, 1 technique per week, to be randomized. The ShotBlocker technique will be applied to patients in any one of 1 weeks(3 days) in a randomized manner.
Study NCT05577832 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard Technique
Description: Standard Technique In a single-group design, 3 technique injections will be administered to the patients, 1 technique per days, to be randomized. The standard technique will be applied to patients in any one of 1 weeks in a randomized fashion.
Study NCT05415592 — intervention group
Intervention type: DEVICE
Intervention: DePuy Synthes Radial Head Replacement System
Description: DePuy Synthes Radial Head Replacement System will be used for radial head replacement or partial replacement of the elbow joint.
Study NCT04696952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TS-142
Description: TS-142
Study NCT04696952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zopiclone
Description: Zopiclone
Study NCT04696952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo
Study NCT05918107 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: PM8002
Description: IV infusion
Study NCT05918107 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Pemetrexed
Description: IV infusion
Study NCT05918107 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Cisplatin
Description: IV infusion
Study NCT05918107 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Carboplatin
Description: IV infusion
Study NCT05285397 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liraglutide Pen Injector [Saxenda]
Description: Subcutaneous injection of GLP-1 agonist
Study NCT06202677 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Self-guided program on obsessive compulsive disorder
Description: This is an 8-day program that provides psychoeducational on what obsessions and compulsions are, and how to identify them. Subsequently, through a series of content learning and daily exercises that increase in difficulty, participants are guided to conduct exposure exercises while tolerating distress and refraining from compulsions. Participants are also guided to set goals and type down the specific content of their intrusive thoughts and compulsive behaviours to keep track of their progress. Each session of the program is estimated to be approximately 5 minutes.
Study NCT06202677 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Self-guided program on cooperation
Description: This 8-day program on cooperation aims to improve participants' collaborative skills and interpersonal wellness through a series of content learning and practice exercises. The time and duration of this program is matched to the obsessive compulsive disorder program to ensure that participants spend a similar amount of time and effort across both the intervention and active control conditions.
Study NCT06356012 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imiquimod
Description: Experimental group will be treated with 16 applications of imiquimod and subsequently LEEP.
Study NCT06356012 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Loop Electrosurgical Excision Procedure
Description: Active comparator group will be treated with LEEP.
Study NCT06356012 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Loop Electrosurgical Excision Procedure
Description: Active comparator group will be treated with LEEP.
Study NCT05500391 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Oncological Follow-up
Description: Post-cancer surveillance (including biological, clinical and imaging exams depending on the condition)
Study NCT05500391 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oncological Follow-up
Description: Post-cancer surveillance (including biological, clinical and imaging exams depending on the condition)
Study NCT04863118 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strength training in shallow water and dry land
Description: Dry land: The intervention will last for 60 minutes, consisting of exercises to strengthen the global extensor musculature, that is, involving the upper limbs, trunk and lower limbs. Weights and equipment for strength training will be used. The sessions will start with 10 minutes of warm-up, the central part of exercises to strengthen the extensor muscles and the last part will consist of oriented stretches. In the central part, a typical strength training will be performed (2-6 series; 85% of RM), using submaximal subjective effort and with repetition control.~Shallow water: The intervention performed on dry land will be adapted and produced in an aquatic environment. Aquatic implements will be used for strength training.
Study NCT04863118 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-intensity training in shallow and deep water
Description: Shallow water: The intervention will last 60 minutes. The exercises consist of: immersion, balance, strength, agility and displacement in the water. As they will start with 10 minutes of warm-up and the last part will consist of stretches oriented along the edge of the pool and on the depth reduction platform. In the main part of the intervention, different styles of exercises will be performed, with or without the use of implements. Displacements will have varying speeds in the same session, defined by Borg's Scale of subjective sensation of effort.~Deep water: The intervention carried out in shallow water will be adapted with the use of floating belts and reproduced in deep water.
Study NCT05412160 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arginine
Description: During the first assessment the patients will be randomized to receive BioArginine C™ twice daily on top of chronic inhaled therapy or to continue their chronic Inhaled therapy plus placebo for 6 weeks. The main purpose is to compare changes in CRQ from baseline and after 6 weeks in the interventional arm compared with the control group in order to evaluate whether in symptomatic patients with COPD, daily bioarginine on top of chronic inhaled therapy can improve respiratory symptoms and dyspnea. The secondary objective of the study is to determine whether there is any correlation between improvement in respiratory symptoms and distance walked at the 6MWT and lung function parameters.