AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06285461 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Non-palatable meal
Description: Participants will consume a meal that corresponds to 40% of their daily resting metabolic rate and balanced diet but with low hedonic reward.
Study NCT06285461 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Palatable meal
Description: Participants will consume a meal that corresponds to 40% of their daily resting metabolic rate and balanced diet but with high-hedonic reward.
Study NCT06366100 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dialectical Behavior Therapy for Substance Use Disorder (DBT-SUD)
Description: In phase 1, DBT online training will consist of the following contents:~Block 1~1.1. Introduction to the key concepts 1.2. DBT-SUD program 1.3. Why DBT for alcohol addiction? 1.4. Proposed content for the group intervention.~Block 2~2.1. DBT skills training modules~In phase 2, DBT-SUD intervention will consist of about the following sessions:~GOALS OF SKILLS TRAINING AND MINDFULNESS:~S1: Goals of skills training; Observing, Describing and Participating~S2: Non-judgmentally, One-mindfulness, Effectively~DISTRESS TOLERANCE:~S3: Crisis Survival skills~S4: Crisis Survival and Radical Acceptance~ADDICTION SKILLS:~S5: Dialectical Abstinence.~S6: Clear Mind~S7: Burning Bridges-Building New Bridges~S8: Community Reinforcement~EMOTIONAL REGULATION:~S9: Identifying emotions and model of emotion~S10: Check the facts. Opposing Action~S11: Problem Solving. Reducing vulnerability~S12: Self-management and rehabilitation
Study NCT06366100 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Unified Protocol (UP)
Description: In phase 1, the UP training will have following contents:~Block 1~1.1. Introduction to key concepts 1.2. Why UP for alcohol addiction? 1.3. Dimensional assessment and case formulation. 1.4. Main characteristics of UP~Block 2~2.1. Modules of UP~In phase 2, UP intervention will consist of:~MOTIVATION:~S1: Motivation enhancement for treatment~UNDERSTANDING EMOTIONS:~S2: Understanding and model of emotions S3: Tracking emotional responses~MINDFULNESS:~S4: Emotion awareness~COGNITIVE FLEXIBILITY:~S5: Cognitive reappraisal to increase thinking flexibility~EMOTION DRIVEN BEHAVIORS:~S6: Emotional avoidance S7: Emotion-driven behaviors and alternative action~AWARENESS AND TOLERANCE:~S8: Tolerance of physical sensations~EMOTIONAL EXPOSURE:~S9: Interoceptive and situational emotion exposure S10: Exposure practice~RELAPSE PREVENTION:~S11: Relapse prevention S12: Review of progress
Study NCT06276673 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Delfi
Description: Cuffs will be worn throughout the entire training session. Training session consist of lower intensity wall squats. Four sets of wall squats will be performed to failure. Arterial stiffness and muscle morphological assessments will be conducted before and after the exercise.
Study NCT06276673 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Delfi
Description: Cuffs will be worn throughout the entire training session. Training session consist of lower intensity wall squats. Four sets of wall squats will be performed to failure. Arterial stiffness and muscle morphological assessments will be conducted before and after the exercise.
Study NCT05694130 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Prednisolone
Description: Oral prednisolone 1mg/kg daily for 4 weeks, then tapered to 7.5mg in 8 weeks.
Study NCT05694130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone
Description: Oral prednisolone 1mg/kg daily for 4 weeks, then tapered to 7.5mg in 8 weeks.
Study NCT05694130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Oral Tacrolimus 1-2mg twice daily for 12 weeks.
Study NCT05131022 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NX-5948
Description: Oral NX-5948
Study NCT05091216 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Chinese Medicine mouthwash
Description: The mouthwash used in this test is based on the records of past traditional Chinese medicine classics and the existing antibacterial experimental evidence. The selected medicinal materials are honeysuckle, scutellaria, peppermint, licorice, and rhizome.
Study NCT05091216 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dilute 50 times of Traditional Chinese Medicine mouthwash
Description: Dilute 50 times of traditional Chinese medicine mouthwash.
Study NCT04167618 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 177Lu-DTPA-omburtamab
Description: Biological, radiolabeled DPTA-omburtamab
Study NCT06051864 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Modius Mood Active Device
Description: Battery powered non-invasive neurostimulation device
Study NCT06051864 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Device
Description: Placebo comparator sham device (no active stimulation)
Study NCT06260878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intravenous Ringer's lactate
Description: Intravenous Ringer's lactate
Study NCT06068023 — intervention group
Intervention type: DRUG
Intervention: Folfirinox
Description: Patients meeting the criteria of post-operative adenocarcinoma of the ampulla of Vater will be enrolled, with adjuvant chemotherapy commencing within 8 weeks of recovery from surgery. Those undergoing palliative intent surgery or palliative chemotherapy are ineligible for the ADAPTA study.~The ADAPTA study's adjuvant chemotherapy involves 8-12 FOLFIRINOX cycles (Arm 2) repeated 2 weeks. Given patient outcomes, 8 cycles of FOLFIRINOX are deemed sufficient due to completion challenges in prior research. FOLFIRINOX regimen mirrors the modified version from the ACCORD/PRODIGE trial for metastatic pancreatic cancer. This trial adapts mFOLFIRINOX for standard practice.
Study NCT06068023 — intervention group
Intervention type: DRUG
Intervention: Capox
Description: or 8 CAPOX cycles (Arm 1) every 3 weeks.
Study NCT05629078 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Toric intraocular lens Zeiss AT TORBI
Description: Intraocular lenses are medical devices that are implanted in patients during cataract surgery. At Plymouth University NHS trust the standard lens is a monofocal non-Toric lens unless the patient has astigmatism greater than 4.00D. This study involves implantation of a toric lens in the intervention group where astigmatism is greater than 1.00D. The lens is called the toric IOLS- Zeiss AT TORBI, will be implanted bilaterally instead of standard monofocal IOLs- Zeiss CT ASPHINA, used in routine cataract surgery within NHS.
Study NCT05712434 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Long Intervention
Description: Each unit will start with iodine protocol, which uses 10% povidone-iodine for disinfection during Foley insertion, for 2 months. After the designated duration of protocol (determined by the results of randomization), each unit will than switched to CHG protocol for 4 months, in which 2% aqueous chlorhexidine solution are used instead of iodine solution. Subsequently, in the final 6-month phase of study, each unit will than switched to CHG plus protocol, in which 0.05% CHG impregnated gel will be used alongside 2% CHG solution during Foley insertion.
Study NCT05712434 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mid-length Intervention
Description: Each unit will start with iodine protocol, which uses 10% povidone-iodine for disinfection during Foley insertion, for 4 months. After the designated duration of protocol (determined by the results of randomization), each unit will than switched to CHG protocol for 4 months, in which 2% aqueous chlorhexidine solution are used instead of iodine solution. Subsequently, in the final 4-month phase of study, each unit will than switched to CHG plus protocol, in which 0.05% CHG impregnated gel will be used alongside 2% CHG solution during Foley insertion.
Study NCT05712434 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Short Intervention
Description: Each unit will start with iodine protocol, which uses 10% povidone-iodine for disinfection during Foley insertion, for 6 months. After the designated duration of protocol (determined by the results of randomization), each unit will than switched to CHG protocol for 4 months, in which 2% aqueous chlorhexidine solution are used instead of iodine solution. Subsequently, in the final 2-month phase of study, each unit will than switched to CHG plus protocol, in which 0.05% CHG impregnated gel will be used alongside 2% CHG solution during Foley insertion.
Study NCT05942560 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioural therapy-based intervention
Description: A specifically designed CBT-based intervention consisting of 8 weekly sessions with group format.~Each group will be comprised of 4-10 participants, and each session will last 1.5 hours.~The content of the weekly sessions will be based on Beck's cognitive theory and the cognitive therapy in groups guidelines.~The framework of every session will follow a pre-determined structure.
Study NCT05942560 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational group
Description: The educational sessions are consisting of 8 weekly sessions with a group format. These sessions will focus on cancer-related information and care knowledge which will be delivered in daily routine care.
Study NCT05720260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Goserelin
Description: Hormone therapy
Study NCT05720260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fulvestrant
Description: Hormone therapy
Study NCT05720260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capivasertib
Description: AKT inhibitor
Study NCT05720260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: immunotherapy
Study NCT05734300 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Combined Endoscopic Laparoscopic Surgery (CELS)
Description: The main surgical advantage in this procedure is the ability to view the colon intra- and extraluminal simultaneously. The laparoscopic approach enables manipulation and mobilization of the colon, while the endoscopic view secures that the resection is complete and not overlapping the ileac valve or creating stenosis.~Compared to the traditional oncological colon resection, the CELS resection is a minimally invasive procedure - organ sparing procedure leading to a reduced surgical stress response.
Study NCT05734300 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Standard resection
Description: In this study standard resection of the colon will be performed according to complete mesocolic excision (CME) principles.
Study NCT04824950 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Circulating tumor DNA monitoring
Description: Monitoring of circulating tumor DNA after 2 and 4 cycles of chemotherapy
Study NCT06364475 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 16:8 Time-Restricted Intermittent Fasting Group
Description: Participants total daily energy expenditures were calculated using the Harris-Benedict formula. This group have a feeding window 8 hours and eating plan of 400 kcal lower than the total daily energy requirement and with similar macronutrient content (50% carbohydrates, 25% fat and 25% protein). Participants in the time-restricted eating group were allowed to drink calorie-free. They were expected to follow their diet for two months during the study.
Study NCT06364475 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Energy-Restricted Six-Meal Group
Description: Participants total daily energy expenditures were calculated using the Harris-Benedict formula. This group have an eating plan three meals and three snacks of 400 kcal lower than the total daily energy requirement and with similar macronutrient content (50% carbohydrates, 25% fat and 25% protein). They were expected to follow their diet for two months during the study.
Study NCT05977439 — intervention group
Intervention type: DEVICE
Intervention: fMRI-EEG-TMS
Description: Participants will undergo a magnetic resonance imaging (MRI) scan with combined electroencephalography (EEG), and single-pulse transcranial magnetic stimulation (TMS) while completing cognitive flexibility (CF) and emotion recognition (CR) tasks.
Study NCT05977439 — intervention group
Intervention type: DEVICE
Intervention: fNIRS-EEG-TMS
Description: Participants brain activity will be measured using functional near-infrared spectroscopy (fNIRS) with combined electroencephalography (EEG), and single-pulse transcranial magnetic stimulation (TMS) while completing cognitive flexibility (CF) and emotion recognition (CR) tasks.
Study NCT05977439 — intervention group
Intervention type: DEVICE
Intervention: fNIRS-EEG-rTMS Interleaved with CBT
Description: Participants brain activity will be measured using functional near-infrared spectroscopy (fNIRS) with combined electroencephalography (EEG), and repetitive transcranial magnetic stimulation (rTMS). rTMS will be delivered via a MagVenture MagPro100 and Cool-B65 coil. The investigators will use a standard resting motor threshold (rMT) determination to determine the TMS dose. Treatment will be delivered at 120% of the motor threshold. The accelerated paradigm will consist 6 session a day for 5-6 days. Each rTMS session will be separated by 30 minutes of Cognitive Behavioral Therapy (CBT). rTMS treatment will be delivered at an individualized left DLPFC target based on each participant's individualized scans from prior neuroimaging sessions.
Study NCT05527197 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Lapiplasty
Description: The Lapiplasty® System instruments and implants will be retrospectively evaluated in patients previously surgically treated with the Lapiplasty® Procedure for Triplane MTP and TMT joint arthrodesis.
Study NCT05490784 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lee Silverman Voice Treatment BIG
Description: Patients assigned to experimental group will get Lee Silverman Voice Treatment BIG along with conventional treatment.
Study NCT05490784 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: patients in this group will get conventional treatment program encompassing set of exercises such as complex motor sequences, stretching, dual tasking, mental imagery and core stability.
Study NCT06500585 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Mill's Manipulation
Description: Mill's Manipulation: The therapist should apply a high-velocity low-amplitude thrust accompanied by a single application . Patients will be treated 3 times a week for 2 consecutive weeks.~Conventional Therapy:~Ultrasound therapy: Frequency: 1Mhz Pulse ultrasound: 1:4 Intensity: 1.5 W/cm2 Duration: 5 min.~Stretching of Wrist Extensors: 15 sec hold, 10 stretches/session/day. Wrist extensors Isometric: resistance 5 to 10 seconds, 15 contractions/ session/day.~Patients will be treated 3 times a week for 2 consecutive weeks.
Study NCT06500585 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mill's Manipulation and Muscle Energy Technique
Description: Mill's Manipulation:The therapist should apply a high-velocity low-amplitude thrust accompanied by a single application . Patients will be treated 3 times a week for 2 consecutive weeks.~Muscle Energy Technique: Extensor carpi radialis stretch for 30 sec repeated 5 times during a single treatment session. Patients will be treated 3 times a week for 2 consecutive weeks.~Conventional Therapy:~Ultrasound therapy: Frequency: 1Mhz Pulse ultrasound: 1:4 Intensity: 1.5 W/cm2 Duration: 5min.~Stretching of Wrist Extensors, 15 sec hold, 10 stretches/session/day. Wrist Extensors Isometric, resistance 5 to 10 seconds, 15 contractions/ session/day.~Patients will be treated 3 times a week for 2 consecutive weeks.
Study NCT04532502 — intervention group
Intervention type: DRUG
Intervention: Anesthetics, Inhalation
Description: Work environmental exposure
Study NCT04907929 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: targeted speech and cognitive therapy
Description: One month of targeted speech and cognitive therapy with a speech therapist and with home exercice at home by using a numeric solution
Study NCT04838652 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab plus Chemotherapy (ICE or DHAP)
Description: Pembrolizumab (200mg) alone or in combination with ICE (or DHAP in case of PET positive findings after P-ICE) will be admistered. 6 additional courses of pembrolizumab will be administered after the completion P-ICE or P-DHAP
Study NCT05745844 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: activity sessions
Description: 77 activity sessions ; muscle strengthening, testing or unloading
Study NCT05745844 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: activity sessions
Description: 77 activity sessions ; muscle strengthening, testing or unloading
Study NCT06260878 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Ringer's lactate
Description: Intravenous Ringer's lactate
Study NCT06639269 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fertility health education program
Description: The intervention group will be implemented with a fertility health education program for which a literature information document will be created. In the training; booklets and brochures will be prepared. The control unit will include information on programming and data collection forms to be used. Those selected from the intervention group will be divided into groups of 10-15 people. The training program will consist of 3 sessions. Training sessions will be planned on days and hours that are convenient for the researcher, classrooms and students. For students who cannot attend group training, make-up training will be provided within a week. In this study, the time between sessions will be planned as 1 week. The sessions in this study will be planned to be in groups of 10-15 people and will last 50 minutes.
Study NCT06242964 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promoting Resilience in Stress Management - Social Needs (PRISM-SN)
Description: The Promoting Resilience in Stress Management - Social Needs (PRISM-SN) intervention is a brief, skill-based psychosocial program. Five core sessions are delivered one-on-one, 1-2 weeks apart, in-person or via videoconference. Sessions teach evidence-based behavioral skills for managing stress, setting goals, reframing negative thoughts, meaning-making, and connecting with others. Each session lasts \<60 minutes and is supported by paper-and-pencil or mobile app-based worksheet(s) for learning and practice. A final review session may be completed individually or with a family member, caregiver, or significant other.
Study NCT06641531 — intervention group
Intervention type: OTHER
Intervention: Screening pap smear test
Description: The patient put in dorsal lithotomy position and place the feet in stirrups or on foot rests . then, the physician will insert a cusco speculum into the vagina to hold vaginal wall open . The specimens will be collected as follows; firstly, the speculum will be inserted without lubricant. Any mucous, discharge or blood will be removed with dry cotton. A wooden spatula will be used for sampling ectocervix which will be rotated 360 degrees. For sampling endocervix, A brush or a swab will be rotated only 90 degrees as the circumferential bristles will be in contact with the entire surface the moment the brush is inserted.~The samples will be applied to the slides which will be encoded and immediately fixed in 95% ethanol and the samples will be transferred to pathology department to be stained by the standard Papanicolaou stain
Study NCT04725110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Instilled T3
Description: The first dose of T3 (50 micrograms in 10 mls volume BID) will be instilled by an investigator or under their direct supervision within 48 hours of obtaining consent after verifying that the patient is not too unstable to treat at that time. T3 doses will be given in 50 mcg doses twice daily for 4 days.
Study NCT04725110 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Therapy
Description: A placebo therapy will be instilled into the lungs by the investigator or under their direct supervision within 48 hours of obtaining consent after verifying that the patient is not too unstable to treat at that time. Doses will be given twice daily for 4 days.
Study NCT06197581 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Chest wall / breast radiation with or without lymph node region radiation.(For all of the enrolled patients)
Description: Patients will receive chest wall / breast radiation with or without lymph node region radiation and novel drugs(for specific population according to guidelines) concurrently.
Study NCT06467435 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Kamuvudine-9
Description: 96 mg tablets taken twice a day for 4 weeks
Study NCT06641661 — intervention group
Intervention type: DRUG
Intervention: Hybutimibe 10mg QD
Description: Hybutimibe was added to the conventional treatment
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent low energy shock wave
Description: Receive divergent low energy shock wave once a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent low energy shock wave
Description: Receive divergent low energy shock wave twice a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent medium and low energy shock wave
Description: Receive divergent medium and low energy shock wave once a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent medium and low energy shock wave
Description: Receive divergent medium and low energy shock wave twice a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Focused low energy shock wave
Description: Receive focused low energy shock wave once a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent medium energy shock wave
Description: Receive divergent medium energy shock wave once a week
Study NCT06563739 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Divergent medium energy shock wave
Description: Receive divergent medium energy shock wave twice a week