AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05733273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single leg bridge exercise program
Description: Week 1 - 1 session per week consisting of 2 sets of 5 reps of the exercise Week 2 - 2 sessions per week consisting of 2 sets of 6 reps of the exercise Week 3 -3 sessions per week consisting of 3 sets of 6 reps of the exercise Week 4 - 3 sessions per week consisting of 3 sets of 8 reps of the exercise Weeks 5 and 6 - 3 sessions per week consisting of 3 sets of the exercise. Set 1 with 12 reps, set 2 with 10 reps and set 3 with 8 reps
Study NCT05733273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hamstring razor curl
Description: Week 1 - 1 session per week consisting of 2 sets of 5 reps of the exercise Week 2 - 2 sessions per week consisting of 2 sets of 6 reps of the exercise Week 3 -3 sessions per week consisting of 3 sets of 6 reps of the exercise Week 4 - 3 sessions per week consisting of 3 sets of 8 reps of the exercise Weeks 5 and 6 - 3 sessions per week consisting of 3 sets of the exercise. Set 1 with 12 reps, set 2 with 10 reps and set 3 with 8 reps
Study NCT05732883 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone injection
Study NCT05732883 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Placebo
Study NCT06438796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Blinatumomab
Description: Maintenance therapy with Blinatumomab initiation: 90 days to 120 days post-transplantation
Study NCT04033029 — intervention group
Intervention type: DRUG
Intervention: Antibiotics
Description: Antibiotic concentration-time data will be collected and analyzed.
Study NCT06268366 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Three exercises consisting of stretching and strengthening specific to the movement pattern dysfunction scored by Symmio will be prescribed to the participants. The exercises are standardized and assigned within the Symmio application with video instruction and guidance.
Study NCT06496698 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Simple Interrupted Suture
Description: In the control group, simple interrupted sutures will be used for wound closure after surgical repair of ankle fractures.
Study NCT06496698 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subcuticular Suture
Description: In the experimental group, subcuticular sutures will be used for wound closure after surgical repair of ankle fractures.
Study NCT05103540 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comprehensive SEM-Based Program
Description: The SEM theorizes that there are multiple inter-related levels of influences on human behavior, and a successful preventive program should address factors at each stratum. My intervention addresses three levels; individual, interpersonal, and social. Firstly, the research will collaborate with relevant stakeholders to design and obtain a commitment from the schools to a suicidal behavior prevention policy and protocol document. Secondly, the intervention will train staff and students on best practices to improve students' connectedness thereby, creating a positive school environment. Thirdly, the study will identify and train gatekeepers on the proper response to suicidal thoughts and other suicidal behaviors; and serve as the link between the students and a school-linked mental health specialist. We will train the gatekeepers to use school-based screening tools. Lastly, this research will educate all students on suicidal behaviors.
Study NCT04765449 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytotoxic T Lymphocytes
Description: Given IV. Cytotoxic T Lymphocytes collected from healthy volunteer donors who have recovered from COVID-19. The T cells are collected, manufactured to be COVID-specific, and stored frozen at Thomas Jefferson University.
Study NCT05853289 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Maternal Opioid use Disorder Management and Care Resources (MOM CARE) in Custody
Description: MOM CARE is a web-based implementation resource designed for jail staff to help the staff provide evidence-based, trauma-informed and patient-centered care and support to pregnant people with opioid use disorder in and leaving custody. MOM CARE's content will include medical guidance and best-practices from intake to discharge, reentry steps and recommendations, and implementation 'how to' content. There will be specific content for jail administrators, medical and custody staff. Content will be curated from existing resources regarding this topic with new original tools specific to pregnant people with OUD in jail.
Study NCT04846634 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Penpulimab+Cisplatin/Carboplatin+Pemetrexed/Paclitaxel/Gemcitabine/Docetaxel
Description: A cycle of treatment is defined as 21 days of once daily treatment.
Study NCT04846634 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Penpulimab+Anlotinib+Cisplatin/Carboplatin+Pemetrexed/Paclitaxel/Gemcitabine/Docetaxel
Description: A cycle of treatment is defined as 21 days of once daily treatment.
Study NCT06529848 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training
Description: The training sessions are consist of cycling and as follows: a 10 min warm-up at a light intensity, 20-35 min of cycling exercise in intervals at varying intensities from light (\~60% of max heart rate) to more intensive (80-90% of max heart rate) and ending with 5 min of warm-down at a light intensity. The training intensity will be progressive during the course of the intervention period. The cycling training sessions are supervised .~Home training is allowed up to once a week if participants are able to adhere to the prescribed intensity levels.~Training sessions are closely monitored to ensure effectiveness and safety. This includes heart rate monitoring, perceived exertion assessment.
Study NCT05547165 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous Patent Ductus Arteriosus Closure (PPC)
Description: Infants in this group will undergo catheter-based PPC closure ≤48 hours following randomization and within 7-days of qualifying ECHO. All participants assigned to PPC will receive the Amplatzer Piccolo™ Occluder which will be implanted within the duct (intraductal placement). The Piccolo™ occluder is approved by the US FDA for this purpose.
Study NCT05547165 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Percutaneous Patent Ductus Arteriosus Closure (PPC)
Description: Infants in this group will undergo catheter-based PPC closure ≤48 hours following randomization and within 7-days of qualifying ECHO. All participants assigned to PPC will receive the Amplatzer Piccolo™ Occluder which will be implanted within the duct (intraductal placement). The Piccolo™ occluder is approved by the US FDA for this purpose.
Study NCT05547165 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Responsive Management Intervention
Description: Interventional PDA-closure, including PPC or surgical ligation and post-randomization pharmacologic (NSAID or acetaminophen) (enteral or intravenous) PDA treatment, are not allowed unless secondary treatment thresholds (see below) are met. Healthcare decisions for Responsive Management will be made at the discretion of the treatment team, while the infant is carefully monitored for any decline in status that may be attributed to the presence of PDA, in which case, Secondary Intervention (described below) may be considered.~Despite widespread acceptance of responsive PDA management, no consensus definition exists. The following Responsive Management interventions are permitted but not required per clinician discretion: 1) fluid restriction between 120-140 mL/kg/day; 2) diuretics (per local practice); 3) increases in positive end-expiratory pressure (PEEP).
Study NCT05547165 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Echocardiogram, cardiac
Description: An echocardiogram, also known as ECHO, is an ultrasound image of the heart. Echocardiography is a common test used for the diagnosis and management of cardiac diseases or conditions.
Study NCT05547165 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Echocardiogram, cardiac
Description: An echocardiogram, also known as ECHO, is an ultrasound image of the heart. Echocardiography is a common test used for the diagnosis and management of cardiac diseases or conditions.
Study NCT05071430 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HB-01
Description: HB-1 will be supplied as a dual active pharmaceutical ingredient tablet.
Study NCT05071430 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: HB-1 matched placebo
Study NCT04846634 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Penpulimab+Anlotinib
Description: A cycle of treatment is defined as 21 days of once daily treatment.
Study NCT04974931 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PREVENA Incision Management System
Description: Eligible participants, i.e. participants meeting inclusive criteria, will be randomised in equal proportions and divided into two arms. The PREVENA dressings will be applied to the
Study NCT05318820 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HMPL-523
Description: This study plans to enroll 39 healthy Chinese subjects who will be randomized (1:1:1) into one of three sequence groups (Test \[T\]/Reference\[R\]/R group, RTR group and RRT group) to receive a single dose in each cycle with a washout period of at least 7 days, where T is the test product \[i.e., HMPL-523 Tablets manufactured by Hutchison MediPharma (Suzhou) Limited.\], and R is the reference product (i.e., HMPL-523 Tablets manufactured by WuXi STA).
Study NCT06382935 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Probin Pocket Depth reduction
Description: Probin Pocket Depth reduction in millimetres before and after treatment
Study NCT06382935 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Probin Pocket Depth reduction
Description: Probin Pocket Depth reduction in millimetres before and after treatment
Study NCT06186531 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: PhytoSERM
Description: PhytoSERM, a formulated dietary supplement, will be an ovalized tablet measuring 8.51 mm x 15.49 mm. Each pill will contain a white PEG coating and an equal mixture of, daidzein, genistein, and S-equol.
Study NCT06186531 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo product is of identical shape, size and color with a white PEG coating but without S-equol, daidzein and genistein.
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbidopa capsule
Description: Dose: 4x 100 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carbidopa capsule
Description: Dose: 4x 100 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Carbidopa capsule
Description: Dose: 4x 100 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxifloxacin Tablets, USP
Description: Dose: 400 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moxifloxacin Tablets, USP
Description: Dose: 400 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Moxifloxacin Tablets, USP
Description: Dose: 400 mg
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo capsules matching the carbidopa capsules
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Placebo capsules matching the carbidopa capsules
Study NCT06161220 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo capsules matching the carbidopa capsules
Study NCT06143670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Stannous fluoride toothpaste
Description: 0.454% w/w SnF2
Study NCT06143670 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium fluoride toothpaste
Description: 0.243% w/w Sodium fluoride
Study NCT04748315 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SEMT(1:1)
Description: Soccer trainning protocolo will be performed on an work to rest ratio 1:1 and the trainning volume will consist of 1 set and 6 repetitions per set
Study NCT04748315 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SEMT (1:3)
Description: Soccer trainning protocolo will be performed on an work to rest ratio 1:3 and the trainning volume will consist of 1 set and 6 repetitions per set
Study NCT05807984 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Carbon ion radiation therapy DT: 74Gy/20 fractions
Description: patients with unresectable local recurrent rectal cancer will be treated with carbon ion radiation therapy as re-irradiation
Study NCT05597072 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Less people within the OR but longer waiting time.
Study NCT05597072 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: More people in the OR but shorter waiting time
Study NCT05170789 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elotuzumab, Selinexor, and Dexamethasone (ESd)
Description: This is a single-arm, interventional, phase II clinical trial, in which the anticipated 18 enrolled patients will receive the trial drug, a combination of Elotuzumab, Selinexor, and Dexamethasone in monthly cycles. The study tests the theory of synergy between these drugs, as detailed in the study description above.
Study NCT06052007 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LC-Based Debriefing
Description: LC-based debriefing encourages reflection by allowing learners to identify and explore topics of particular interest. The model is defined as a structured post-event LC, which is useful for improving competence, professional development, and clinical judgment among intensive care unit and trauma nurses. The model is useful not only for one recipient by allowing reflection on positive and negative experiences but also for the whole group by allowing them to make connections to their own practice that day or to previous experiences, supporting teamwork. It also helps them understand what good practice is by doing their own self-assessment with peers' benchmarking.
Study NCT06052007 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3D Model-Based Debriefing
Description: The model has three parts: defusing, discovering, and deepening. The experiential learning theory on which this model is based facilitates learning goals. This model allows its participants to create new mental models for future practice, develop critical thinking skills, and identify knowledge gaps. In the model, a debriefing session starts with preliminary information and ends with a summary of what has been learned. Participants' gaps in understanding and learning are identified, and how they can apply their learnings to practice is discussed.
Study NCT03637387 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BIIB074
Description: Administered as specified in the treatment arm
Study NCT03637387 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered as specified in the treatment arm.
Study NCT05871554 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mind-OP+
Description: Mind-OP is an online program designed to cultivate mindfulness and self-compassion developed by Beshai and his team. Mind-OP is self-guided, with four modules administered at a pace of one module per week (four weeks total). The version used for this study, Mind-OP+, is five weeks total, containing an extra module focused on connectedness.~The modules contain psychoeducational videos, guided audio meditations, goal-setting and motivational interviewing inspired exercises. Participants also have opportunities to engage with meditations and other exercises embedded within each module.~The first module (Week 1) introduces the concept of mindfulness. The second module (Week 2) focuses on attention to bodily sensations and thoughts. The third module (Week 3) introduces the concept of self-compassion. The fourth module (Week 4) focuses on the self-kindness component of self-compassion. The fifth module (Week 5) focuses on the concept of connectedness.
Study NCT05707793 — intervention group
Intervention type: OTHER
Intervention: Evaluating sexual function, quality of life and pelvic floor muscle strength, as well as thickness and force (strength) of voluntary contractions of the core muscles
Description: Evaluation through Vaginal Laxity Questionnaire, Female Sexual Function Index, Short-Form 36 Health Survey, modified Oxford grading scale and ultrasound imaging
Study NCT05024058 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ligelizumab
Description: Ligelizumab treated groups and arms
Study NCT05024058 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo treated groups and arms
Study NCT05043493 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Injection in the intraarticular space of glenohumeral joint
Description: U/S guided injection of platelet rich plasma (PRP) or normal saline (NS)
Study NCT05043493 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Injection in the intraarticular space of glenohumeral joint
Description: U/S guided injection of platelet rich plasma (PRP) or normal saline (NS)
Study NCT05345431 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: endovascular denervation
Description: Treating with EDN at the site of the iliac artery distal to the superficial femoral artery proximal before balloon dilation or stent implantation
Study NCT05345431 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: PTA
Description: Treating with balloon dilation or stent implantation
Study NCT04730739 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: FastFrame External Fixation System - Knee Spanning or Damage Control Kit
Description: The FastFrame External Fixation Systems - Knee Spanning Kit and Damage Control Kit are single-use external fixators that are sterile packed with all required components for convenience of the end user.
Study NCT04064346 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lixivaptan
Description: Oral vasopressin V2 receptor antagonist
Study NCT04064346 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo
Study NCT05338203 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tandem breastfeedıng
Description: mother mılk wıll collected from mothers and they wıll be analyzed in laboratuar.
Study NCT04930354 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ECP-1014
Description: Patients will be selected who (1) have failed all standard of care therapy (relapsed/refractory) or (2) have relapsed and are not a candidate for an available standard of care therapy as assessed by the investigator (such as, but not limited to, colorectal cancer (CRC), Non-Small Cell Lung Cancer (NSCLC), head and neck, etc.) with COX-2 overexpression, ultimately resulting in elevated production of prostaglandin E2 (PGE2).
Study NCT06208059 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: manual acupuncture
Description: In manual acupuncture, the scalp motor area on the lesion side will be needled and left in place for 30 minutes after obtaining qi. During the needle retention, the needles will be twisted intermittently for 2 minutes twice, at a frequency of approximately 200 r/min.
Study NCT06208059 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electroacupuncture
Description: In electroacupuncture, the scalp motor area will be needled, and after obtaining qi, the treatment will involve applying electroacupuncture stimulation using a continuous wave with a frequency of 2 Hz. The intensity of the stimulation will be adjusted based on the patient's tolerance, and each treatment session will last for 30 minutes.
Study NCT05551494 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Urinary sample
Description: At study entry, we will collect urinary samples from women. Participants will be asked with an interview on demographic and lifestyle characteristics, health-related behaviours, the existence and duration of infertility, medical history, and history of hormonal or surgical treatments for endometriosis. Pain symptoms will be evaluated through a 10 cm long one-dimensional visual-analogue scale (VAS).~In addition, women will be asked to report about their habits about consumption of plastic
Study NCT06423144 — intervention group
Intervention type: PROCEDURE
Intervention: TACE/HAIC
Description: TACE/HAIC were performed within 1 month prior/after the first PD-1/PD-L 1 inhibitor/antiangiogenic drug treatment;
Study NCT06423144 — intervention group
Intervention type: DRUG
Intervention: PD-1/PD-L1 inhibits and anti-angiogenic agents
Description: Agents were administrated based on the instructions recommended
Study NCT05302154 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Distraction by dentist
Description: Basic behavior orientation techniques (tell-show-do) is applied by the dentist during the treatment.
Study NCT05302154 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Distraction by cartoon movie
Description: Children watch cartoons on a screen mounted dental unit during the treatment.