AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05663840 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive resistance exercise
Description: Patients with predominant symptoms of cervical dystonia will receive exercise training. Patients will receive progressive resistance exercise focused cervical and shoulder training (PERFECT) plus standard-of-care (SOC) therapy. Resistance training will consist of mainly muscle-strengthening exercises for the neck, shoulder and arms and a few upper trunk muscles. Resistance training will be guided by physical therapists at twice a week schedule for 6 months. These participants will also receive SOC therapy.
Study NCT05663840 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Subjects will receive SOC therapy only
Study NCT05891899 — intervention group
Intervention type: OTHER
Intervention: observation
Description: No interventions planned: treatment of patients at the discretion of the treating/responsible physician
Study NCT06124768 — intervention group
Intervention type: PROCEDURE
Intervention: Percutaneous mechanical thrombectomy (PMT) by the modified approach
Description: The modified approach includes the ipsilateral calf venous access and the contralateral femoral venous access. Through contralateral femoral venous access, a hydrophilic guide wire and a catheter will be crossover through the thrombus side to the distal calf vein. The ipsilateral calf venous access will be punctured under the guidance of ascending venography. A hydrophilic guide wire and a catheter will be used to pass through the thrombus antegrade to the inferior vena cava. Percutaneous mechanical thrombectomy (PMT) catheter will be used to clear the thrombus. After PMT treatment, residual thrombus will be reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) will be conducted if there is residual thrombus. Percutaneous balloon angioplasty (PTA) and stenting will be conducted if there is >50% stenosis of the diameter of the iliac vein.
Study NCT06124768 — intervention group
Intervention type: PROCEDURE
Intervention: Percutaneous mechanical thrombectomy (PMT) by the traditional approach
Description: The traditional approach will be punctured from the ipsilateral popliteal vein under ultrasound guidance. A hydrophilic guide wire and a catheter will be used to pass through the thrombus antegrade to the inferior vena cava. Percutaneous mechanical thrombectomy (PMT) catheter will be used to clear the thrombus. After PMT treatment, residual thrombus will be reevaluated by ascending venography. Catheter-directed thrombolysis (CDT) will be conducted if there is residual thrombus. Percutaneous balloon angioplasty (PTA) and stenting will be conducted if there is >50% stenosis of the diameter of the iliac vein.
Study NCT06516861 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine IV
Description: Administered intravenously with a dose of 1.5mg/Kg
Study NCT05968846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Injection of peptide p5+14 radiolabeled with iodine-124 (124I-AT-01)
Description: 124I-AT-01 (124I-p5+14, iodine-124I evuzamitide) is a a novel iodine-124 (124I) labeled 45 L-amino acid peptide suitable for PET/CT imaging that has been shown to bind systemic amyloid deposits of diverse types in all organs, including the heart. The peptide binds amyloid through multivalent electrostatic interactions with the amyloid fibril and ubiquitous heparan sulfate proteoglycans.
Study NCT06230965 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Lung protective ventilation strategy
Description: They were divided into 2 groups: traditional ventilation strategy group (control group) and lung protective ventilation strategy group (experimental group), with 30 cases in each group. In the conventional ventilation strategy group, the conventional ventilation strategies were followed: tidal volume （VT）=10-12ml/kg, respiratory rate（f） =12 times/minute, PEEP=0 cmH₂O, fraction of inspired oxygen=0.5; Lung protective ventilation strategies were implemented in the Lung protective ventilation strategy group: VT=6-8ml/kg, f=12 times/min, PEEP=6-8 cm H₂O,fraction of inspired oxygen=0.5 Manual lung reexpansion was performed every 30 minutes after mechanical ventilation (continuous positive airway pressure of 30 cm H₂O for 30 seconds).
Study NCT06230965 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Lung protective ventilation strategy
Description: They were divided into 2 groups: traditional ventilation strategy group (control group) and lung protective ventilation strategy group (experimental group), with 30 cases in each group. In the conventional ventilation strategy group, the conventional ventilation strategies were followed: tidal volume （VT）=10-12ml/kg, respiratory rate（f） =12 times/minute, PEEP=0 cmH₂O, fraction of inspired oxygen=0.5; Lung protective ventilation strategies were implemented in the Lung protective ventilation strategy group: VT=6-8ml/kg, f=12 times/min, PEEP=6-8 cm H₂O,fraction of inspired oxygen=0.5 Manual lung reexpansion was performed every 30 minutes after mechanical ventilation (continuous positive airway pressure of 30 cm H₂O for 30 seconds).
Study NCT04700423 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: moxidectin (8 mg) / albendazole (400 mg)
Description: Combination therapy of moxidectin (8 mg using 2 mg tablets) plus albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0
Study NCT04700423 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ivermectin (200 µg/kg) / albendazole (400 mg)
Description: Combination therapy of ivermectin ((200 µg/kg), 3 mg tablet) plus albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0
Study NCT06516861 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: saline solution
Description: Administered intravenously with 20 ml
Study NCT04700423 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL]
Description: Monotherapy of albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0
Study NCT04700423 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ivermectin (200 µg/kg)
Description: Monotherapy of ivermectin ((200 µg/kg), 3 mg tablet) administered orally at day 0
Study NCT04700423 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: moxidectin (8 mg)
Description: Monotherapy of moxidectin (8 mg, using 2 mg tablets) administered orally at day 0
Study NCT05228054 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: laser procedure
Description: In modified litothomy position patients with hemorrhoidal deasease will be treated with transcutaneous laser 1940nm 3watt in impulse regimen
Study NCT05613816 — intervention group
Intervention type: PROCEDURE
Intervention: Senhance Surgical System
Description: 100 patients affected by uterine diseases with indication for hysterectomy undergo treatment with robotically assisted laparoscopic procedures using the Senhance Surgical System
Study NCT05437757 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical implantation of the PCL Breast scaffold with autologous fat grafting
Description: Single shot of prophylactic perioperative antibiotics is given to the patient. A suitable incision is made to provide access followed by mobilisation of the breast gland.If present, the silicone implant is removed and capsulectomy performed. The implant pocket shall be rinsed with saline or antiseptic and a surgical drain shall be placed in the pocket at the discretion of the PI. The PCL Breast scaffold shall be inserted into the pocket and fixed using 2 to 4 sutures. The incision is closed. Liposuction is performed from another area of the body and lipofilling is performed within the breast scaffold. Sterile bandaging is applied and a daily wound revision is performed whilst an inpatient. A prophylactic antibiotic shall be administered to the patient.The patients shall be hospitalized overnight for clinical observation.
Study NCT06432465 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active tDCS
Description: The anode will be placed over the right DLPFC (F4 on the EEG 10-20 system) and the cathode over the left DLPFC65 (F3) using 25cm2 sponges at an intensity of 2mA. Stimulation will be delivered for 20 minutes via two saline-soaked surface sponge electrodes and a battery-driven, constant current stimulator (NeuroConn DC Stimulator Plus).
Study NCT06432465 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tDCS
Description: Same device and procedures as active tDCS with the exception that the device includes a study mode, in which subject-specific codes are entered to deliver active or sham stimulation, keeping the administrator blinded. Sham stimulation will use a method in which stimulation will be ramped up and back down over a 30-second period at the beginning and end of sham tDCS.
Study NCT04650490 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: Timing of stereotactic radiosurgery relative to immunotherapy
Study NCT04650490 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: Physician's choice of immunotherapy per standard of care
Study NCT05986032 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Respiratory Oscillometry
Description: Measurement of respiratory system reactance by respiratory oscillometry
Study NCT05752500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Intervention for Physical Activity
Description: Interventionist will use cognitive and behavioral techniques to help the participant increase facilitators and decrease barriers to physical activity, particularly barriers such as lack of motivation, depression, and chronic pain. Meetings will occur every other week for 4 months.
Study NCT05752500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Support for Physical Activity
Description: This component will leverage the social functionality of the Fitbit app, promoting social support and friendly competition via a moderated Facebook group.
Study NCT05752500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity Coaching
Description: The PA coach will meet with the participant to set goals for physical activity (steps) and encourage self-monitoring. Meetings will occur every other week for 4 months.
Study NCT05228054 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: sclerotherapy
Description: In modified litothomy position patients with hemorrhoidal deasease will be treated with sclerotherapy with Aethoxysklerol
Study NCT05459259 — intervention group
Intervention type: OTHER
Intervention: Interviews and Delphi Survey
Description: no intervention delivered
Study NCT05752500 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.
Study NCT05752500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Advice and Self-Monitoring
Description: Participants will receive a single session with brief advice about increasing physical activity, and instructions on how to use their study-provided FitBit.
Study NCT05857748 — intervention group
Intervention type: DRUG
Intervention: lifitegrast
Description: patient newly started on medication will be followed for 6 months
Study NCT04742270 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SIMEOX+ respiratory physiotherapy telecare
Description: Every 10 days, the patient's expert physiotherapist will contact the patient by video-transmission or telephone call for motivational reinforcement and technical support in the use of the device.~During these phone calls, a quick 3-question questionnaire will be administered to the patient to monitor events of hemoptysis, chest pain and clinical symptoms of gastroesophageal reflux disease: pyrosis.If patients report this type of event, the physiotherapist will inform the patient's physician for management at his/her discretion.~The expert physiotherapist will also conduct this sessions in order to increase the patient's motivation and compliance to the device. In order to do this, he will identify (in collaboration with the patient), the patient's difficulties and obstacles and he will try to find solutions with him.
Study NCT05202769 — intervention group
Intervention type: OTHER
Intervention: Video filming
Description: Video clips taken using RGB and thermal imaging cameras under varying conditions of lighting, movement and procedures taking place.
Study NCT05675241 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical examination of a dental implant
Description: Clinical examination includes bleeding on probing, pocket depth, gingival biotype, suppuration, gingival index
Study NCT05675241 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Radiological Examination
Description: A standardized periapical radiograph in parallax technique will be taken.
Study NCT05675241 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Peri-implant crevicular fluid sample collection
Description: A sample of the peri-implant crevicular fluid will be collected using paper strip for 60 seconds. The sample of the fluid will be a resultant of inserting six different strips at the same time in six sites of the implant including mesiobuccal, midbuccal, distobuccal, distopalatal/distolingual, midpalatal/midlingual, mesiopalatal/mesiolingual sites of the implant.
Study NCT05338021 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrawound administration of vancomycin after closure of the arthrotomy
Description: After closure of the arthrotomy, 1 g of vancomycin powder suspended in 30ml of normal saline was injected directly into the joint with an 18-gauge needle.
Study NCT04476628 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Budesonide
Description: Budesonide is a corticosteroid that is commonly used intranasally to treat CRS.
Study NCT04476628 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Mucosal Atomization Device
Description: MAD is a device used as an addition to a syringe to atomize medication to increase area of distribution. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.
Study NCT04476628 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: NeilMed squeeze bottle for Impregnated Nasal Saline Irrigation
Description: INSI is delivered using a NeilMed squeeze bottle. It is used to administer budesonide within the nasal passages and sinuses to administer medication for CRS.
Study NCT04961905 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002-R1+NVP-2002-R2
Description: NVP-2002-R1 1 tablet, once daily and NVP-2002-R2 1 tablet, once daily
Study NCT05231174 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A self-evlaution tool based on Large Language Model
Description: Following the baseline assessment, participants will be guided to use a self-evaluation tool independently to assess their risk of diabetic retinopathy (DR). This tool is a fusion of a conversational AI system based on LLM and an existing logistic diagnostic model.~The AI system is designed to collect clinical variables, including age, duration of diabetes, Body Mass Index (BMI), and insulin usage. Additionally, clinical test data such as mean arterial pressure, HbA1c, serum creatinine, and microalbuminuria will be extracted from a local dataset using the patient's name and ID. Once collected, these data will be transmitted to a server-based diagnostic model for further analysis to determine the presence of DR.
Study NCT04742426 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WHO recommended PPE
Description: Uses polycarbonate safety spectacles, fluid-resistant (Type IIR) surgical mask and disposable surgical gown. No head or foot cover.
Study NCT04961905 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NVP-2002
Description: NVP-2002 is a combination of NVP-2002-R1 and NVP-2002_R2 NVP-2002, 1 tablet, once daily
Study NCT04742426 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Super-safe setup
Description: Uses surgical cap, FFP3 respirator covered by surgical mask, face shield, whole-body suit (Tyvec), 3 pairs of gloves typed to suit sleeves and disposable foot cover.
Study NCT06258135 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Galacto-oligosaccharide
Description: Single 7g dose daily for 28 days
Study NCT06258135 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Single 7g dose daily for 28 days
Study NCT06170801 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Kiesler Circle Training (KCT)
Description: Kiesler Circle Training is a transdiagnostic modular group treatment, which comprises a baseline module and four additional independent modules (nonverbal communication, verbal communication, conflict training and empathy and corrective interpersonal experiences). KCT is based on a heuristic model to explain and anticipate interactions developed by Donald Kiesler and other representatives of the interpersonal theory. The circumplex model arranges the variety of interpersonal behaviors in terms of a circular continuum allocated on two orthogonal axes: The vertical axis addresses interpersonal control (agency), the horizontal axis addresses interpersonal communion. The model further allows illustrating complementary action tendencies to anticipate other's reactions and to guide own behavior to achieve interpersonal goals. KCT is designed for increasing the awareness of such interpersonal action tendencies and for improving interpersonal behavioral flexibility.
Study NCT06170801 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy is based on the interrelationships of thoughts, actions and feelings. Presumably, individual CBT will address intrapersonal therapeutic foci such as behavioral activation, identification of dysfunctional thoughts, overcoming fears by exposure, etc. Individual CBT may also include interpersonal functioning as therapeutic foci. Disorder-specific treatment manuals are available for all diagnoses included in the study. Of note, state-of-the-art CBT does not necessarily mean, that individual CBT-sessions strictly adhere to a manual. However, because both study sites are CBT training institutes, which guarantee supervision at least every four hours, it can be estimated that state-of-the-art CBT is realized.
Study NCT06170801 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy (CBT)
Description: Cognitive Behavioral Therapy is based on the interrelationships of thoughts, actions and feelings. Presumably, individual CBT will address intrapersonal therapeutic foci such as behavioral activation, identification of dysfunctional thoughts, overcoming fears by exposure, etc. Individual CBT may also include interpersonal functioning as therapeutic foci. Disorder-specific treatment manuals are available for all diagnoses included in the study. Of note, state-of-the-art CBT does not necessarily mean, that individual CBT-sessions strictly adhere to a manual. However, because both study sites are CBT training institutes, which guarantee supervision at least every four hours, it can be estimated that state-of-the-art CBT is realized.
Study NCT02590523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin
Description: Intracameral vancomycin injection during cataract surgery
Study NCT02590523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxifloxacin
Description: Intracameral moxifloxacin injection during cataract surgery
Study NCT02590523 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intracameral placebo injection with BSS during cataract surgery
Study NCT04677530 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-40411813
Description: JNJ-40411813 will be administered orally.
Study NCT04677530 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Matching Placebo
Description: Matching placebo will be administered orally.
Study NCT04696458 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus plantarum (CECT7484 and CECT7485)/ Pediococcus acidilactici (CECT7483)
Description: Probiotic Capsules in blister packets of capsules containing the probiotic intervention contain a combination of three strains of lactic acid bacteria: two Lactobacillus plantarum (CECT7484 and CECT7485) and one Pediococcus acidilactici (CECT7483).
Study NCT04696458 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Placebo
Description: Placebo Capsules in blister packets of capsules containing the inert (controlled) non-interventional treatment.
Study NCT05869552 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STAT-PC
Description: STAT-PC is an adapted version of Suicidal Teens Accessing Treatment after an ED Visit (STAT-ED). It is a brief intervention based on motivational interviewing (MI) that focuses on mental health care seeking behavior, problem-solving, and referrals plus brief case management. The intervention will consist of an initial session with the youth focusing on accessing mental health care plus case management calls. The interventionist will also be available to assist with referrals for connection to other services later during the study period as needed for up to three months. The intervention may include contact with the youth's mental health provider to make sure linkages are made.
Study NCT05869552 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: YST-III
Description: YST-III is an adapted version of Youth-Nominated Support Team for Suicidal Adolescents (YST-II). The intervention is a brief intervention originally developed for youth who have been psychiatrically hospitalized due to a suicide attempt or suicidal ideation (SI). Participants will nominate supportive adults (age 18 and older) from their lives who agree to provide ongoing contact and support for up to 3 months. YST-III will include an introductory session with the youth who will nominate their support persons plus referrals for mental health services. The support persons will receive training and support on how to best support their youth partner and then ongoing calls to support them in working with their youth partner for up to 3 months.
Study NCT05378516 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention