AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03750838 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text Messaging Intervention
Description: The content for the text messaging Intervention will be designed to be non-confrontational in tone, seek to increase motivation to drink lightly or not at all, and based both on general information about light and non-drinking as well as information provided during the baseline assessment.
Study NCT04843904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Tablet, taken by mouth
Study NCT04843904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Given as an infusion into the vein (intravenous, IV).
Study NCT04843904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: Given as an infusion into the vein (intravenous, IV).
Study NCT04723368 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automated flying Drone carrying an Automated external defibrillator (AED)
Description: Totally n=5 drones are equipped with automated external defibrillators (AEDs). These drones are deployed by the dispatch centre to cases of suspected out-of-hospital cardiac (OHCA) as a complement to standard care (ambulance/EMS) over up to 14 months during daytime Monday to Sunday 08:00-22:00. The bystander onsite receives instructions from the dispatcher to retrieve the AED outside the house when it has been delivered by the drone. The bystander attaches the AED to the patients chest to facilitate early defibrillation.
Study NCT05023655 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tazemetostat
Description: 800mg po twice daily
Study NCT05434676 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Shockwave Medical Peripheral Intravascular Lithotripsy (IVL) System M5 & S4
Description: To assess the safety and effectiveness of IVL treatment used in combination with DCB to treat moderate and severely calcified femoropopliteal arteries
Study NCT05162391 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Contingency Management
Description: Contingency management intervention with incentives tied to provision of urine samples with no detectable levels of methamphetamine (MA).
Study NCT05467137 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MSOT
Description: MSOT imaging (after ICG injection)
Study NCT06738030 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial current stimulation
Description: The transcranial alternating current stimulation is delivered during the speech stimulus and the current matches the envelope of the target speech
Study NCT06738030 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Auditory training
Description: An at-home auditory training program that adaptively and interactively trains the listener in degraded speech, cognitive skills, and communication strategies
Study NCT05203965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mavoglurant (AFQ056)
Description: Two 100mg tablets of Mavoglurant will be administered on the morning of one of the two experimental days by a RN or the physician investigator.
Study NCT05203965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Two matching tablets of placebo will be administered on the morning of one of the two experimental days by an RN or the physician investigator.
Study NCT05465720 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: falls-prevention programs
Description: Each group will receive 10-minute warm up, followed by 20-minute exercises in the ICF body function level, 20-minute exercises in the ICF activity level, and finally 10-minute cool down. The 10-minute war up include dynamic mobility exercises of the upper extremity and trunk (ribbons dancing on a chair) and of the lower extremity (marching in place). The 10-minute cool down include flexibility exercises of multiple muscles especially focusing on neck, hamstring, and calf muscles.
Study NCT05465720 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: falls-prevention programs
Description: Each group will receive 10-minute warm up, followed by 20-minute exercises in the ICF body function level, 20-minute exercises in the ICF activity level, and finally 10-minute cool down. The 10-minute war up include dynamic mobility exercises of the upper extremity and trunk (ribbons dancing on a chair) and of the lower extremity (marching in place). The 10-minute cool down include flexibility exercises of multiple muscles especially focusing on neck, hamstring, and calf muscles.
Study NCT05683184 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: [11C]OMAR
Description: For each \[11C\]OMAR PET scan, up to 20 mCi of \[11C\]OMAR will be administered.
Study NCT06738030 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Auditory training
Description: An at-home auditory training program that adaptively and interactively trains the listener in degraded speech, cognitive skills, and communication strategies
Study NCT06740097 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aspirate tissue monitoring
Description: This multicenter controlled clinical trial investigates the clinical performance and outcomes from using an aspirate tissue monitor (ATM, Marginum Ltd HIVEN™) that detects cancerous tissue from the suction waste during the surgical treatment of suspected high-grade gliomas. The ATM provides near real-time audible feedback to the surgeon when tumor-related fluorescence is detected in the aspirated tissues. The trial investigates if the use of ATM to detect 5-ALA induced fluorescence contributes to faster tumor removal, less blood loss, less unintended residual tumor, less morbidity, longer survival and the frequency of local reoperations. The cases are compared with controls (n=50) from applicable local clinical site registers (matched controls). The cases are operated with the help of aspirate tissue monitoring and the controls without. Other preferred adjunct techniques are used in both groups.
Study NCT06361407 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Illusion task
Description: The task is the illusion already described in the arm description. All participants will additionally benefit from a short neuropsychological evaluation exploring attention (CPT-AX) and semantic knowledge (fNART) and a clinical evaluation exploring the sense of self (EASE).
Study NCT06055686 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Electrical Epidural Stimulation Test
Description: Electrical stimulation test measures sensory/motor responses
Study NCT06064318 — intervention group
Intervention type: PROCEDURE
Intervention: Revision
Description: Any type of knee revision, excluding knee arthrodesis and femur amputation
Study NCT04431427 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Biliary drainage with PC-SEMS
Description: partially covered metallic biliary stent insertion during ERCP
Study NCT04431427 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Biliary drainage with U-SEMS
Description: Uncovered metallic biliary stent insertion during ERCP
Study NCT05176210 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PS1
Description: PS1 will be provided as a 120 mg tablet with 25 mg active pharmaceutical ingredient.
Study NCT05176210 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be provided as a 120 mg tablet.
Study NCT05734937 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: gastric assessment of gastric volume
Description: ultrasound assessment of gastric volume is going to bel evaluted in the Preoperative and postoperative period while the patients lay in right lateral decubitus position.
Study NCT05300529 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vestibular Rehabilitation Exercises
Description: The Vestibular Rehabilitation program focuses on stabilizing the gaze and gaining the Vestibular Ocular Reflex (VOR). The general mechanisms of recovery from vestibular injuries are vestibular adaptation and replacement exercises, which are designed to improve gaze stability and the interaction between sight and the vestibular system during head movements. The exercises will be carried out progressively according to the tolerance of the patient, varying the stimulus in intensity and frequency.
Study NCT05300529 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Conventional Rehabilitation exercises
Description: The conventional rehabilitation program in which exercises are performed to improve joint range, flexibility, and gait. It will always be done with the eyes open, on a firm surface and will not include training in sensory strategies
Study NCT05677945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3Mixtatin paste: Simvastatin mixed with modified triple antibiotic
Description: * Drying the mucosa with gauze,topical anesthesia will be applied.~* Administration of local anesthesia with vasoconstrictor.~* Rubber dam isolation.~* Caries removal \& access cavity using a round bur mounted on a high-speed contra with coolant.~* Removal of necrotic pulp tissue in coronal portion of the tooth using sharp excavator.~* Radicular section will be kept untouched,no instrumentation.~* Using disposable syringe Irrigation of the pulp chamber with 2.5% NaOCl.~* In case of hemorrhage moist cotton immersed in 1% NaOCL will be placed to achieve hemostasis.~* Drying the access cavity with sterile cotton pellets.~* Freshly mixed 3Mix-MP or 3Mixtatin paste (according to group of intervention) will be transferred to the floor of the pulp chamber using an amalgam carrier \& condensed over orifices using a moist cotton pellet.~* Cavity sealing with RMGI capsules.~* Same visit placement with preformed Stainless-steel crown(3M® ESPE)cemented with glass ionomer cement.
Study NCT05677945 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 3Mix: Modified triple antibiotic mix in propylene glycol
Description: * Drying the mucosa with gauze,topical anesthesia will be applied.~* Administration of local anesthesia with vasoconstrictor.~* Rubber dam isolation.~* Caries removal \& access cavity using a round bur mounted on a high-speed contra with coolant.~* Removal of necrotic pulp tissue in coronal portion of the tooth using sharp excavator.~* Radicular section will be kept untouched,no instrumentation.~* Using disposable syringe Irrigation of the pulp chamber with 2.5% NaOCl.~* In case of hemorrhage moist cotton immersed in 1% NaOCL will be placed to achieve hemostasis.~* Drying the access cavity with sterile cotton pellets.~* Freshly mixed 3Mix-MP or 3Mixtatin paste (according to group of intervention) will be transferred to the floor of the pulp chamber using an amalgam carrier \& condensed over orifices using a moist cotton pellet.~* Cavity sealing with RMGI capsules.~* Same visit placement with preformed Stainless-steel crown(3M® ESPE)cemented with glass ionomer cement.
Study NCT06656234 — intervention group
Intervention type: DRUG
Intervention: Glofitamab
Description: Glofitamab will be administered at the discretion of the physician per local clinical practice and local labeling.
Study NCT06656234 — intervention group
Intervention type: DRUG
Intervention: Obinutuzumab
Description: Obinutuzumab pre-treatment is given intravenously at a dose of 1g on Cycle 1 Day 1.
Study NCT05627193 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Teleclinic
Description: Instead of visiting surgeon after travelling from far flung areas for a post surgery follow up appointment, the follow up visit will be done using telephone.
Study NCT05627193 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Clinic
Description: Patients will have to travel to come physically to hospital to meet the operating surgeon.
Study NCT05811195 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Diode Semiconductor, Duo
Description: Intraoral photobiomodulation therapy (660nm, 3s/point, 10J/cm²) for the management for the oral mucositis in pediatric patients. Mainly in the decrease of oral mucositis rates severity, healing of the ulcers of OM. The results obtained will be compared with the other group.
Study NCT05811195 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gemini laser
Description: Extraoral photobiomodulation therapy (810 + 980 nm, 20s/point, 4.07J/cm²) for the management for the oral mucositis in pediatric patients. Mainly in the decrease of oral mucositis rates severity, healing of the ulcers of OM. The results obtained will be compared with the other group.
Study NCT05082155 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine 0.25%
Description: Bupivacaine 0.25% will be delivered as a basal infusion of 1 mL/h and an automatic intermittent bolus of 20 mL every 4 hours.
Study NCT05082155 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Normal Saline
Description: Normal saline will be delivered as a basal infusion of 1 mL/h and an automatic intermittent bolus of 20 mL every 4 hours.
Study NCT05340907 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality Device
Description: A virtual reality headset is a heads-up display (HUD) that allows users to interact with simulated environments and experience a first-person view (FPV). VR headsets replace the user's natural environment with virtual reality content, such as a movie, a game or a pre-recorded 360-degree VR environment that allows the user to turn and look around, just as in the physical world. Patient undergoing bronchoscopy will be given the device before and during the procedure.
Study NCT06138873 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ablation-index guided ventricular tachycardia ablation
Description: As described in arms descriptions
Study NCT06124677 — intervention group
Intervention type: DRUG
Intervention: Faricimab
Description: The Injections were performed according to local standard protocol, that included the use of 2-3 drops of topical tetracaine anesthesia, use of eye speculum, topical 5% povidone-iodine disinfection, a 30G-needle, injection site 3.5 mm posterior from the limbus marked by calipers in supertemporal or inferotemporal quadrants, a sterile cotton tip tamponade at the site of injection after removal of the needle, and no post-procedure antibiotics.
Study NCT06740097 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Fluorescence-guided surgery
Description: Resection utilizing conventional visual fluorescence-guided surgery.
Study NCT05428917 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Simple task
Description: The subject is seated on a chair facing a table, both hands resting on the table.~The subject is asked, for each block of 20 seconds, to perform flexion / extension movements of the fingers of the left hand at 0.5 Hz.
Study NCT05428917 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: complex task
Description: The subject is seated on a chair facing a table, both hands resting on the table.~The subject is asked, for each block of 20 seconds, to perform an exercise based on the nine hole peg test
Study NCT06739577 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Evaluation of walking abilities (manual Timed-Up & Go - TUG and automatic -OpenTUG))
Description: To evaluate walking abilities, participants performed the Timed-Up \& Go (TUG) f our times (practice trial, normal, slow and fast speed). Patient's performances are videorecorded with an Intel RealSense depth camera D435i to capture their movements, and manual time recording of time taken (in seconds) and number of steps are carried out by the experimenters.~Complementary to manual experimenter recording, a 2D human pose estimation method (OpenTUG) is applied to automatically extract the time and the number of steps taken by the participant during the TUG task.
Study NCT06739577 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Neuropsychological assesment is provide to measure objective and subjective cognition/emotional aspects.
Description: Neuropsychological evaluation assess attention (Test for Attentional Performance -TAP-) and quality-of-life (DHI, HADS, and NVI).
Study NCT05319054 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sacral NeuroModulation
Description: Sacral Neuromodulation group will include up-to 20 patients with major LARS. Medtronic Interstim system will be used, including 2 week trial device.
Study NCT05319054 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Trans-Anal Irrigation
Description: Trans-Anal irrigation group will include up-to 20 patients with major LARS. Specific system will be agreed with the patient, depending on eligibility and preference.
Study NCT05319054 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Optimised Conservative Management
Description: Optimised conservative management will include up-to 30 patients with major LARS. They will be provided with a resource booklet which includes dietary and lifestyle advice as well as exercises that can be undertaken independently.
Study NCT06737068 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device
Description: Elective robot assisted hiatal hernia repair with low pressure pneumoperitoneum (8-10mmHg) with AirSeal device
Study NCT06737068 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
Description: Elective robot assisted hiatal hernia repair with standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational varicella vaccine_Lot 1
Description: Investigational varicella vaccine of Lot 1 administered subcutaneously.
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational varicella vaccine_Lot 2
Description: Investigational varicella vaccine of Lot 2 administered subcutaneously.
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Investigational varicella vaccine_Lot 3
Description: Investigational varicella vaccine of Lot 3 administered subcutaneously.
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Marketed varicella vaccine_Lot 1
Description: Marketed varicella vaccine of Lot 1 administered subcutaneously.
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Marketed varicella vaccine_Lot 2
Description: Marketed varicella vaccine of Lot 2 administered subcutaneously.
Study NCT04574960 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gemcitabine
Description: Gemcitabine 1000 mg/m\^2, IV infusion on days 1 and 8 of each 3-week cycle
Study NCT04574960 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine 1000 mg/m\^2, IV infusion on days 1 and 8 of each 3-week cycle
Study NCT04574960 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Cisplatin 70 mg/m\^2, IV infusion on day 1 of each 3-week cycle
Study NCT04574960 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Cisplatin 70 mg/m\^2, IV infusion on day 1 of each 3-week cycle
Study NCT04574960 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin AUC 5-6 calculated using the Calvert formula on day 1 of each cycle
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MMR vaccine
Description: MMR vaccine co-administered subcutaneously or intramuscularly.
Study NCT06319495 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.~Particularly, due to dysphagia, the patients enrolled might face difficulty in eating. For patients who were able to finish intake via mouth by compensatory means, the consistency, type, and size of food bolus was arranged. For those who cannot acquire sufficient nutrition through oral intake, the nasogastric tube feeding was provided.
Study NCT06319495 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Rehabilitation therapy
Description: During the treatment, All the participants were provided with the rehabilitation therapy, which included routine rehabilitation, cognitive training, swallowing function training and nutrition support.~Particularly, due to dysphagia, the patients enrolled might face difficulty in eating. For patients who were able to finish intake via mouth by compensatory means, the consistency, type, and size of food bolus was arranged. For those who cannot acquire sufficient nutrition through oral intake, the nasogastric tube feeding was provided.
Study NCT06319495 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: Based on the invention above, the patients in the observation group were provided with Stellate ganglion block, using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g). The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.
Study NCT06740630 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: MMR vaccine
Description: MMR vaccine co-administered subcutaneously or intramuscularly.