AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06073184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mounjaro
Description: Tirzepatide injection, starting dose is 2.5mg injected subcutaneously once weekly. After 4 weeks, dose should be increased to 5mg once weekly. The dose then can be increased in 2.5mg increments after no less than 4 weeks on current dose to maximum dose of 15mg once weekly.
Study NCT06073184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirena
Description: Levonorgestrel-releasing Intrauterine System (52mg) to deliver up to 20 mcg levonorgestrel per day
Study NCT06138431 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT
Description: Virtual CBT groups
Study NCT06519955 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
Description: Weight 50-74.9 kg:~* ropivacaine 100mg/epinephrine 50 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 75-99.9 kg:~* Ropivacaine 150mg/epinephrine 100 mcg/ketorolac 15mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total~Weight 100+ kg:~* Ropivacaine 200mg/epinephrine 150 mcg/ketorolac 15 mg in NaCl 0.9% 60mL~* 2 vials of this for 120mL total
Study NCT05457335 — intervention group
Intervention type: PROCEDURE
Intervention: undergoing PGT
Description: Preimplantation genetic testing for aneuploidy
Study NCT06373419 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TFL
Description: Participant undergoing bladder tumour resection that has been randomized to this arm.
Study NCT06373419 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MOSES holmium laser
Description: Participant undergoing bladder tumour resection that has been randomized to this arm.
Study NCT05588375 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: home-based physical activity telemonitoring program
Description: The home telehealth physical activity training program is a telemedicine physical activity training that uses Google Meet software to communicate and supervise through webcams.
Study NCT05588375 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: home-based physical activity telemonitoring program
Description: The home telehealth physical activity training program is a telemedicine physical activity training that uses Google Meet software to communicate and supervise through webcams.
Study NCT05467449 — intervention group
Intervention type: DEVICE
Intervention: DxFLEX 10C
Description: A device combining flow cytometry and reagents for immunophenotyping analysis
Study NCT05397522 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Exercise by a physiotherapist via face to face
Description: The exercises are performed by the participants under the supervision of a physiotherapist via face-to-face.
Study NCT05397522 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supervised Exercise by a physiotherapist via video conference
Description: The exercises are performed by the participants under the supervision of a physiotherapist via video conference.
Study NCT05799495 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07817883
Description: Arm 1: low dose Arm 2: medium dose Arm 3: high dose
Study NCT05799495 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06477445 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Visual feedback balance training system
Description: Using an visual feedback balance training system to provide a dynamic balance training platform for patients to perform balance training based on visual feedback.
Study NCT06477445 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: repetitive facilitative exercise
Description: Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.
Study NCT06477445 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: repetitive facilitative exercise
Description: Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.
Study NCT06477445 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: Basic training, including passive joint movement and activities of daily living exercise.
Study NCT05124457 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Detemir
Description: Patients are to receive insulin detemir
Study NCT05124457 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Insulin NPH
Description: Patients are to receive insulin NPH
Study NCT05648591 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iloperidone
Description: oral tablet
Study NCT06572371 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic pyeloplasty
Description: The first trocar was inserted under vision through the same supraumbilical incision and the intraperitoneal cavity was inspected The second 5 mm trocar was placed in the midclavicular line 2 inches below the costal margin. The third 10 mm trocar was placed lateral to the rectus muscle at the level of the anterior superior iliac spine. In right-sided pyeloplasty, a fourth trocar was inserted below the xiphistemum for liver retraction. Incision of the line of Toldt and mobilization of the colon was the first step of the transperitoneal approach. A 4/0 polysorbe stay suture was taken in the lateral aspect of the ureter distal to uretero-pelvic junction obstruction to identify the correct orientation after dismembering the ureter. A full thickness anastomosis was started from the angle of V shape spatulation to the lower pole of the renal pelvis.
Study NCT06572371 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open pyeloplasty
Description: A flank incision with the patient in lateral position was undertaken in open pyeloplasty. After accessing the retro- peritoneum, the ureter was identified and traced cranially till the PUJ segment.~Traction sutures was placed on the renal pelvis followed by excision of the narrowing segment. The ureter was spatulated by approximately 2 cm and a reduction pyeloplasty was performed, where necessary. Anastomosis was undertaken using vicryl 4-0 sutures. The primary anastomotic site was sutured in interrupted fashion followed by a continuous running suture of the posterior wall. Next, antegrade DJ stenting was performed and the anterior wall was anastomosed. After haemostatic control a 22 Fr drain was placed in the surgical bed.
Study NCT04906018 — intervention group
Intervention type: DEVICE
Intervention: Ultrasound scans
Description: Each subject will be randomly allocated to an ultrasound machine and an expert scanner who will perform the ultrasound scans of all supported anatomical regions.
Study NCT05668195 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: systematic aerobic exercise and intelligent monitoring system in executive skill training
Description: This is a closed-loop training initially developed by the research team in conjunction with other teams, adding a systematic aerobic exercise and intelligent monitoring system to the typical executive skill training, and is being further explored in training.
Study NCT05668195 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: executive skill training
Description: The training program, based on Dawson and Guare's (2010) training of executive skills for children, aimed to improve the everyday performance of executive skills among children with ADHD. Qian Y and her team added some culturally adapted information, following the theory of cognitive behavioral therapy, to ensure that the concepts were acceptable to Chinese children.
Study NCT05668195 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: executive skill training
Description: The training program, based on Dawson and Guare's (2010) training of executive skills for children, aimed to improve the everyday performance of executive skills among children with ADHD. Qian Y and her team added some culturally adapted information, following the theory of cognitive behavioral therapy, to ensure that the concepts were acceptable to Chinese children.
Study NCT05023915 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: diammonium glycyrrhizinate enteric-coated capsule
Description: 150mg tid for 3 months
Study NCT06368297 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketone Monoester Supplementation
Description: Exogenous ketones are a class of ketone bodies that are ingested using nutritional supplements or foods. This class of ketone bodies refers to the three water-soluble ketones (acetoacetate, β-hydroxybutyrate \[β-HB\], and acetone).
Study NCT06368297 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: The ketogenic diet typically reduces total carbohydrate intake to less than 50 grams a day-less than the amount found in a medium plain bagel-and can be as low as 20 grams a day. Generally, popular ketogenic resources suggest an average of 70-80% fat from total daily calories, 5-10% carbohydrate, and 10-20% protein.
Study NCT04942626 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Kineret 100 MG in 0.67 ML Prefilled Syringe
Description: Anakinra 100 mg s.c. (Kineret) will be administered from day -10 (i.e. 10 days before initiation of RT) to the last day of RT.
Study NCT04942626 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Capecitabine
Description: Capecitabine will be administered using a 3+3 dose escalation design (500 mg/m2 bid, 650 mg/m2 bid and 825 mg/m2 bid po, respectively) from day 1 to day 40 of RT including weekends.
Study NCT04942626 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Radiotherapy
Description: PTV: 1.8 Gy to 45 Gy (#28 fractions) to the primary tumor and pelvic lymph nodes; followed by a sequential boost of 1.8 Gy to 9 Gy (#5 fractions) to the gross tumor volume
Study NCT04942626 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Watch and Wait (cCR) or TME surgery (non-cCR)
Description: Restaging to evaluate tumor response will be conducted 10 weeks after completion of CRT. For patients achieving a clinical complete response (cCR), a Watch and Wait (W\&W) option with close follow-up is scheduled. In case of non-cCR, immediate total mesorectal excision (TME) surgery is recommended. According to the current German S3-guidelines, adjuvant chemotherapy is optional.
Study NCT06410482 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: US guided caudal block
Description: After placing the patient in the left lateral position (hips and knees flexed) following monitoring and induction of anaesthesia, the field will be sterilized with 70% alcohol in 2% chlorhexidine.~Initial scanning in the transverse plane allows for visualization of the midline and identification of the sacrococcygeal ligament between the 2 sacral cornua. The 2 cornua resemble the 2 eyes of a frog and thus are collectively called the frog-eye sign. The US probe is then rotated 90 degrees to acquire a longitudinal view. The needle is then advanced at a 20-degree angle with needle tip and length visualization Once the needle is confirmed to be in the caudal space on the screen, carefully aspirate to confirm absence of CSF or blood.~A slow injection of the local anaesthetic can then be performed, dose of (0.2 mL/kg 0.25% bupivacaine and 1 μg/kg of dexmedetomidine
Study NCT06410482 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal penile nerve block
Description: after general anesthesia induction. With the patient in the supine position. After skin sterilization the US linear probe will be transversely placed on the root of the penis. After placing the penis in gentle traction, a50 mm block needle will be inserted from the lateral part of the penis root towards the dorsal section of the penis with the in-plane technique, It will be advanced through Dartos fascia until resistance to the needle disappeared.~Once the superficial sheath will be passed, the tip of the needle will be advanced into Buck's fascia and then positioned between Buck's fascia and tunica albuginea, lateral to the dorsal artery. After making sure there will be no blood with negative aspiration, half of the total 0.2 mL/kg dose of 0.25% bupivacaine will be administered while observing its distribution with US. The same procedure will be then repeated on the other side of the penis.
Study NCT04742725 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT04742725 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prothione™ (6g)
Description: Prothione is a pro-Glutathione compound includes free-form amino acids
Study NCT05933733 — intervention group
Intervention type: OTHER
Intervention: Salvage treatment (surgery and/or radiation therapy)
Description: Appropriate salvage treatment (surgery and/or radiation therapy) will be selected by the treating clinicians considering the disease status.
Study NCT05402865 — intervention group
Intervention type: DRUG
Intervention: Denosumab
Description: Denosumab, subcutaneous injection, specific usage to see the medical records. Non-denosumab, specific usage to see the medical records.
Study NCT06034600 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: taping
Description: Taping will be applied to the exercise and taping group after the exercises with theraband. Other exercises that are not performed will be performed with the tape on the skin.The application will be repeated three days a week for eight weeks.
Study NCT06279936 — intervention group
Intervention type: OTHER
Intervention: Neuropsychological battery
Description: COVID-19 patients with persistent complaints of cognitive disabilities (more than 4 weeks post-infection) in daily life are examined with an extensive neuropsychological test battery (see below) at the outpatient clinic of the University Psychiatric Centre in Duffel and at the University Hospital Antwerp. This battery covers a broad range of reliable and valid tests divided into six cognitive domains: attention, memory, visuospatial functions, language, executive functions and psychomotor speed/coordination. The neuropsychological examination lasts an average of 2 hours per participant. The tests are carried out by the same experienced neuropsychologist and also follow a standardized sequence. In addition to the neuropsychological assessment, two self-report scales are filled out by each patient. These scales are used to detect possible complaints of fatigue and possible cognitive problems which are experienced by the patient during daily life activities.
Study NCT06279936 — intervention group
Intervention type: OTHER
Intervention: Surveys and symptom severity questionnaires
Description: Both self-rated surveys and clinician administered questionnaires
Study NCT06279936 — intervention group
Intervention type: OTHER
Intervention: Blood withdrawal
Description: Blood samples will be collected in a standardized manner by venipuncture. Two blood vials will be collected and processed to perform the following analyses:~* serum collection tube(s) allowing for HERV-W ENV and serological assays~* plasma collection tubes for the assessment of other immune-related biomarkers (including but not limited to CRP, IL-6, IL-1b, TNF-a, IFN-g, tryptophan, kynurenine, 3-OH-kynurenine, quinolinic acid, kynurenic acid, enzymes of the kynurenine pathway).
Study NCT06279936 — intervention group
Intervention type: OTHER
Intervention: Saliva swabs
Description: Salivary cortisol measures will be used as functional measure of the HPA axis activity, as the unbound cortisol fraction in saliva is highly correlated to plasma cortisol. Baseline diurnal cortisol and CAR levels will be measured using saliva, collected at home with Salivette® (Sarstedt) synthetic swabs. The rationale behind the choice of home sampling, is to maximize normal circumstances and to minimize stress related to the measuring procedure.
Study NCT04988269 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sampling
Description: Assessment of circulating levels of plasma ACTH, plasma aldosterone and serum interleukin -6 levels at day 1
Study NCT04988269 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Saliva sampling
Description: Assessment of diurnal variation of cortisol and DHEA levels in the saliva at 4 different time points during the day (0.800, 12.00, 18.00, 22.00) at day 2.
Study NCT04717752 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ovidrel
Description: recombinant human chorionic gonadotropin for injection
Study NCT04717752 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Ovidrel
Description: recombinant human chorionic gonadotropin for injection
Study NCT04717752 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Troprilin
Description: triptorelin acetate injection
Study NCT06034600 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise
Description: Stretching and strengthening exercises will be applied to both groups three days a week for 8 weeks.The exercises performed with theraband will be performed in the same way in both groups. While the other exercises will be done after taping in the taping and exercise group, the exercise group will be done without taping.
Study NCT06403592 — intervention group
Intervention type: OTHER
Intervention: optic nerve sheath diamater
Description: Measurement of optic nerve sheath diameter
Study NCT05635214 — intervention group
Intervention type: PROCEDURE
Intervention: real time remote tele mentored ultrasound exam
Description: A patient will have a point of care ultrasound exam performed by a local provider with a remote expert guiding them through the exam using video conferencing.
Study NCT06288113 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT06288113 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo PET/CT and SPECT/CT
Study NCT06288113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gallium Ga 68 Gozetotide
Description: Given IV
Study NCT06288113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lutetium Lu 177 Vipivotide Tetraxetan
Description: Given IV
Study NCT06288113 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET/CT
Study NCT06288113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06288113 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single Photon Emission Computed Tomography
Description: Undergo SPECT/CT
Study NCT06223945 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Prevention algorithm
Description: Development of an algorithm for the prevention of thrombohemorrhagic complications
Study NCT06432127 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Unilateral Greater occipital nerve block at C2 level under ultrasound guide with needle in plane technique during ultrasound using normal saline 3 mL
Study NCT06432127 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine
Description: Unilateral Greater occipital nerve block at C2 level under ultrasound guide with needle in plane technique during ultrasound using 0.5% Bupivacaine 3 mL
Study NCT05461092 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine
Description: Patient receives standard of care anesthesia with TLIP Block of bupivicaine (local anesthetic) intraoperatively after anesthesia administration and before spinal fusion.
Study NCT05461092 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood Test
Description: Blood Tests measuring inflammatory markers: IL-10, MCP-1, IL-8, IL-6, TNFa
Study NCT05461092 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood Test
Description: Blood Tests measuring inflammatory markers: IL-10, MCP-1, IL-8, IL-6, TNFa
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 3D CAM Delirium Severity Scoring
Description: Questionnaire that will rate each symptom of delirium
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 3D CAM Delirium Severity Scoring
Description: Questionnaire that will rate each symptom of delirium
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Generalized Anxiety Disorder 7-item (GAD-7) scale
Description: Questionnaire for screening and severity measurement of generalized anxiety disorder.
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Generalized Anxiety Disorder 7-item (GAD-7) scale
Description: Questionnaire for screening and severity measurement of generalized anxiety disorder.
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Numerical Rating Score (NRS)
Description: Questionnaire assessing pain intensity
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Numerical Rating Score (NRS)
Description: Questionnaire assessing pain intensity
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PROMIS-Pain Interference
Description: Questionnaire measuring the effect of pain on patient physical, emotional, and social functioning.
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PROMIS-Pain Interference
Description: Questionnaire measuring the effect of pain on patient physical, emotional, and social functioning.
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oswestry Disability Index (ODI)
Description: Questionnaire assessing disability and quality of life impairment in adults with lower back pain.
Study NCT05461092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oswestry Disability Index (ODI)
Description: Questionnaire assessing disability and quality of life impairment in adults with lower back pain.