AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05335317 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: King's Health Questionnaire
Description: The King's Health Questionnaire will be used to collect feedback on changes in the participants life quality (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: King's Health Questionnaire
Description: The King's Health Questionnaire will be used to collect feedback on changes in the participants life quality (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. pH (potential of hydrogen) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. pH (potential of hydrogen) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. pH (potential of hydrogen) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound investigation
Description: Ultrasound investigation with General Electric Voluson E8 Expert for assessing blood vessels (Doppler sonography) and vaginal wall thickness measurement (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound investigation
Description: Ultrasound investigation with General Electric Voluson E8 Expert for assessing blood vessels (Doppler sonography) and vaginal wall thickness measurement (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Perineometry
Description: Pressure force of vaginal walls measurement with IEASE device (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Perineometry
Description: Pressure force of vaginal walls measurement with IEASE device (to evaluate procedure efficiency).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Optical coherence tomography
Description: Optical non-invasive method of investigation vaginal mucus morphological and functional condition.
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Optical coherence tomography
Description: Optical non-invasive method of investigation vaginal mucus morphological and functional condition.
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Biopsy of the vaginal wall to assess the condition of the vaginal wall and compare the obtained data with the data of optical coherence tomography.
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Biopsy
Description: Biopsy of the vaginal wall to assess the condition of the vaginal wall and compare the obtained data with the data of optical coherence tomography.
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Femoflor screen
Description: Femoflor screen for the study of vaginal microbiocenosis, specifically for the detection of the pathogens, opportunistic flora and normal flora and their qualitative and quantitative evaluation (to include the participant in the study).
Study NCT05335317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Femoflor screen
Description: Femoflor screen for the study of vaginal microbiocenosis, specifically for the detection of the pathogens, opportunistic flora and normal flora and their qualitative and quantitative evaluation (to include the participant in the study).
Study NCT05642481 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Therapeutic drug monitoring in plasma of mother and child and in breastmilk
Description: Measurement of drug concentration in plasma of mother and if possible of child and in breastmilk
Study NCT01184287 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ranpirnase
Description: Cycles 3 and until patient progression, on days 1,8 and 15 in a 21 day cycle
Study NCT04881201 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: blood sample
Description: blood sample
Study NCT05198466 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electrical Stimulation
Description: Subjects will receive an active electrical stimulation device to wear for 1 hour daily for 4 weeks (phase II).
Study NCT05198466 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Electrical Stimulation - Sham
Description: Subjects will receive a sham electrical stimulation device to wear for 1 hour daily for 4 weeks (phase II).
Study NCT06143241 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Threshold IMT
Description: Threshold is used in respiratory muscle training in the form of resistance loading.
Study NCT05275257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of Uricap Female, a New Urine Collecting Device
Description: The uridome is changed daily by trained staff
Study NCT05717634 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Hysteroscopy
Description: Patients with suspected endometrial pathology, will undergo hysteroscopy with endometrial biopsy or endometrial lesion excision.
Study NCT04994834 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotics
Description: Once a day daily intake of probiotics for at least 28 consecutive starting within 24 hours after birth
Study NCT05008666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: 1. To evaluate the short-term objective efficacy of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~2. To evaluate the long-term efficacy and safety of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~3. Exploring biomarkers that may have predictive effects.
Study NCT05008666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chidamide
Description: 1. To evaluate the short-term objective efficacy of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~2. To evaluate the long-term efficacy and safety of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~3. Exploring biomarkers that may have predictive effects.
Study NCT05008666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: 1. To evaluate the short-term objective efficacy of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~2. To evaluate the long-term efficacy and safety of sintilimab Sequential combined with chidamide and azacitidine in the treatment of ENKTL-HLH patients.~3. Exploring biomarkers that may have predictive effects.
Study NCT05008666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-DEP
Description: L-DEP
Study NCT06010082 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Music Therapy
Description: Music Therapy intervention will be delivered through instructed participants to empty their bladder and then listen to music for 30 min in a semi-fowler's position with their head and shoulders raised 30° in a quiet and dim environment, listening to the music of symphonic music.
Study NCT06010082 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: Music Therapy intervention will be delivered through instructed participants to empty their bladder and then listen to music for 30 min in a semi-fowler's position with their head and shoulders raised 30° in a quiet and dim environment, listening to the music of symphonic music.
Study NCT06143241 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antiepileptic medication
Description: They will continue their antiepileptic medication prescribed by their doctor.
Study NCT06143241 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antiepileptic medication
Description: They will continue their antiepileptic medication prescribed by their doctor.
Study NCT05068817 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates mat exercises
Description: Pilates mat exercises: Each Pilates session will last for one hour and commence with a 10 minute warm up and finish with a 10 min cool down. The subjects will be taught the 5 key elements of Pilates (lateral costal breathing, centring which is a neutral position of the lumbar spine with activation of the core muscles, ribcage placement, shoulder blade placement and neutral position of the cervical spine with slight upper cervical flexion at the cranio-cervical junction).~Pilates exercise program will consist of warm up exercises, main treatment program (10 level) and cooling down exercises.
Study NCT05068817 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cervical stabilization exercises
Description: training of deep cervical flexor muscles with pressure biofeedback unit, 20 min/day, 3 days/week for 12 weeks.
Study NCT05068817 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physiotherapy
Description: 10 min hot pack on cervical area range of motion exercises and isometric neck exercises as a home program 3 days/week for 12 weeks
Study NCT05068817 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional physiotherapy
Description: 10 min hot pack on cervical area range of motion exercises and isometric neck exercises as a home program 3 days/week for 12 weeks
Study NCT04891419 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: JUVÉDERM® VOLUMA® with Lidocaine
Description: JUVÉDERM® VOLUMA® with Lidocaine injectable gel
Study NCT04659655 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: automated annular suturing
Description: RAM® Automated Suturing Technology. The RAM® DEVICE and SEW-EASY® DEVICE are automated suturing devices indicated for use in the approximation of soft tissue and prosthetic materials when used in conjunction with RAM® COR-SUTURE® QUICK LOAD® surgical suture. Devices will be used for the approximation of respective replacement valves during surgical aortic or mitral valve replacement as described in the study protocol. Cases may include use of the RAM® RING/RAM® RACK devices for suture management and the Aortic Root Retractor (ARR) with delivery device.
Study NCT05208138 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senhance Surgical System from Asensus
Description: Bariatric operation with the Senhance Surgical System
Study NCT04929769 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total Laparoscopic or Robotic Radical Hysterectomy
Description: Radical hysterectomy with bilateral pelvic lymph node dissection is performed as standard type C RH by Q-M classification, including cardinal ligaments divided at pelvic sidewall and uterosacral ligaments divided at near the sacral origin and the upper 1/4 to 1/3 of the vagina.
Study NCT04929769 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Total Abdominal Radical Hysterectomy
Description: Radical hysterectomy with bilateral pelvic lymph node dissection is performed as standard type C RH by Q-M classification, including cardinal ligaments divided at pelvic sidewall and uterosacral ligaments divided at near the sacral origin and the upper 1/4 to 1/3 of the vagina.
Study NCT05979909 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitomycin C
Description: Mitomycin (40 mg in 40 mL of sterile water) will be administered through a Foley catheter, which will be clamped for two hours.
Study NCT05579418 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Evolocumab
Description: Evolocumab is an injection for management of dyslipidemia
Study NCT05449834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fibrinogen Concentrate
Description: 3g Fibrinogen Concentrate
Study NCT05449834 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cryoprecipitate
Description: 10U WB or 4U Apheresis Cryoprecipitate
Study NCT01229540 — intervention group
Intervention type: GENETIC
Group type: NO_INTERVENTION
Intervention: genetic analyzer
Study NCT06264531 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab 5 mg/kg as a slow infusion over 90 minutes every 14 days for a total of 6 injections
Study NCT06264531 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: NaCl 0.9% slow infusion over 90 minutes every 14 days for a total of 6 injections
Study NCT05318287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Walk with Me
Description: Walk with Me is a perinatal grief mobile application to provide supportive care to bereaved parents. The application includes modules to guide bereaved parents through strategies to help support them through their grieving.
Study NCT04648150 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Evaluation of a millimeter wave emission bracelet for improving Parkinson's disease symptoms
Description: Evaluation of a millimeter wave emission bracelet -type medical device for improving Parkinson's disease symptoms: multicenter, double-blind randomized controlled trial
Study NCT04648150 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Evaluation of a millimeter wave emission bracelet for improving Parkinson's disease symptoms
Description: Evaluation of a millimeter wave emission bracelet -type medical device for improving Parkinson's disease symptoms: multicenter, double-blind randomized controlled trial
Study NCT06670664 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention. This is a single-group study.
Study NCT06681987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: simulation training
Description: One group of students will practice computer-based simulation for pre-eclampsia and eclampsia case management skills using a high-fidelity simulator (n = 15) (subgroups n=3), while the other group will practice with a low-fidelity model (n = 15; subgroups n=3). In the first stage, the case will be written for the high-fidelity simulator and will be submitted to the opinions of experts in the field. After the necessary arrangements are made, the groups will be randomized and allocated. In the second stage, the experimental group will be presented with a virtual reality simulator, and the control group will be presented with a case example of preeclampsia and eclampsia with a low-level simulator. In order to evaluate and increase the teamwork skills of the students in the experimental and control groups, the students will be divided into subgroups of three.
Study NCT06719505 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ME
Description: Exercises selected with a focus on the major muscle groups. There will be one protocol for the first 3 months and a second protocol for months 4-6, with the number of repetitions for each exercise varying from 3 sets of 8 to 10 repetitions, totaling 18 exercises.
Study NCT06719505 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PE
Description: The stretching and strengthening exercises will target the major muscle groups, and at the end of each session (lasting approximately 60 minutes), the instructor will guide the participant through a relaxation exercise using an EVA foam roller. The exercises were selected to improve overall muscle strength, as traditionally applied in Pilates. There will be one protocol for the first 3 months and a second protocol for months 4-6, with 17 exercises in each protocol, varying from 3 sets of 8 to 10 repetitions.
Study NCT06723951 — intervention group
Intervention type: OTHER
Intervention: QUALAS survey
Description: Participants will be asked to complete the surveys at one (controls) and two (patients) timepoints.
Study NCT06722976 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multicomponent exercise programs
Description: The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.~1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).~2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each session.~3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).
Study NCT06723912 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Action Process Approach-Based Program
Description: Health Action Process Approach-Based Program: The program is planned for six weeks (six sessions). Sessions will be held once a week for 30-45 minutes. Within the scope of the program, care - structured nursing care plans based on the Health Action Process Approach will be made -, education and counseling will be provided. Sessions will be held in a quiet, calm environment in the hospital, and if such an environment cannot be provided, they will be held at the patient's home. The day, time and place of the sessions will be decided together with the participant after each interview or session. At the beginning of each session, the previous session will be briefly recalled and the homework (SWOT analysis, treatment adherence tracking chart or SMART goal plan) given in the previous session will be evaluated. At the end of each session, the evaluation of that day's session will be carried out briefly.
Study NCT06733779 — intervention group
Intervention type: OTHER
Intervention: observation
Description: cross-sectional study
Study NCT06724276 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: balloon angioplasty and stenting of lower extremity vessels + fibroblasts
Description: A balloon or a stent of the required size (according to the intrinsic diameter of the affected vessel) is delivered to the affected area, sequential balloon dilatation with exposure of up to 5 minutes or stenting of the vessel is performed. After completion, control angiography is performed with evaluation of the result. Instruments, introdjuncer are removed. Manual compression haemostasis (up to 20 minutes over the puncture site) followed by aseptic pressure dressing on the puncture site for 12 hours with bed rest. After surgery, fibroblasts will be applied to the wound for 24 hours.
Study NCT06724276 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: balloon angioplasty and stenting of lower extremity vessels
Description: A balloon or a stent of the required size (according to the intrinsic diameter of the affected vessel) is delivered to the affected area, sequential balloon dilatation with exposure of up to 5 minutes or stenting of the vessel is performed. After completion, control angiography is performed with evaluation of the result. Instruments, introdjuncer are removed. Manual compression haemostasis (up to 20 minutes over the puncture site) followed by aseptic pressure dressing on the puncture site for 12 hours with bed rest.
Study NCT06731946 — intervention group
Intervention type: DEVICE
Intervention: Flow diverting
Description: Flow diverter has become the standardized treatment method for Intracranial aneurysms (IAs), which is different from angioplasty, coiling, etc.
Study NCT06732908 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: LipoMicel Berberine
Description: Berberine powder in a LipoMicel matrix encapsulated in soft gel.
Study NCT06732908 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: microcrystalline cellulose
Study NCT06724965 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trans STAIR
Description: Skills Training in Affect and Interpersonal Regulation (STAIR) is a transdiagnostic evidenced-based mental health treatment for individuals who have experienced multiple traumas. STAIR is based in cognitive-behavioral principles and delivered in a flexible manner over 8 group sessions, with demonstrated efficacy for the treatment of PTSD and other mental health symptoms. This trial will adapt and pilot test the STAIR intervention to be culturally appropriate and acceptable for TGD persons, adding content related to TGD health and wellness, coping with minority stress, responding to stigma and microaggressions, social support, and community connectedness, self-compassion, celebrating trans joy, trans advocacy, sexual health and PrEP use.
Study NCT06724965 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: PrEP Well
Description: This pilot trial will leverage PrEP Well, a multi-level implementation strategy for providing PrEP in TGD-serving contexts by integrating peer-led PrEP navigation with programming that addresses other social and structural needs of the TGD community (e.g., housing, legal, employment, gender-affirmation, primary care)
Study NCT06724965 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PrEP Well
Description: This pilot trial will leverage PrEP Well, a multi-level implementation strategy for providing PrEP in TGD-serving contexts by integrating peer-led PrEP navigation with programming that addresses other social and structural needs of the TGD community (e.g., housing, legal, employment, gender-affirmation, primary care)