AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05754593 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Antral follicle count (AFC)
Description: Measure of Antral follicle count (AFC) by ultrasound imaging
Study NCT05754593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Antral follicle count (AFC)
Description: Measure of Antral follicle count (AFC) by ultrasound imaging
Study NCT05754593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical assessment
Description: MS history and MS treatments and Expanded Disability Status Scale (EDSS) score will be recorded
Study NCT05934331 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM302+Toripalimab
Description: LM-302 in combination with Toripalimab.
Study NCT05044754 — intervention group
Intervention type: PROCEDURE
Intervention: Local treatment of the prostate (SCAP or HIFU)
Description: Once the local involvement of the recurrent prostate cancer is confirmed, patient will undergo local treatment of the prostate (SCAP or HIFU)
Study NCT05920772 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KickAsh! intervention
Description: The general aim of the KickAsh! intervention is to prevent smoking initiation in adolescents living in vulnerable socioeconomic situations. The intervention exists of different components concerning smoking prevention. Most components have a direct influence on smoking initiation by affecting several determinants of the adolescents. These components include smoke-free games, mood boards, a smoke-free camp, the Kick some Ash!-challenge and exercises concerning self-efficacy and skills. Yet, some of the components target adolescents by influencing their environment, i.e. smoking policy in the organisation and youth workers as role models. All components are developed using a combination of theoretical methods to change or influence these determinants or environmental factors.
Study NCT05216627 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Self-administered saliva-based viral testing
Description: Participants will be instructed on how to inactivate the virus and bring their sample to their laboratory's central PCR machine, where they will take an assay test. They will be instructed to collect saliva into a 1.5 milliliter (mL) collection tube containing inactivation buffer (TCEP and EDTA) using a small funnel and inactivate at 95°C for 10 minutes. Participants will then transfer 6ul of saliva into 2 PCR tubes containing amplification master mix and primers, put tubes in a heat block or PCR machine at 65°C for 45 minutes and assess fluorescence using a simple battery-powered fluorescence viewer. Once they assess their sample, they will be instructed to dispose of the saliva sample safely and in accordance with best laboratory practices. No saliva samples will be collected by the research team at any time as part of this study.
Study NCT06530719 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib mesylate
Description: Osimertinib mesylate , 80mg QD，until the duration of treatment reaches 3 years, the disease progresses, or other treatment termination criteria are met
Study NCT05001139 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Relizema ecofoam
Description: DermoRelizema ecofoam, class II a medical device, topical compact mousse, to be applied 2 times per day during the 42 days of study duration
Study NCT05283590 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Automated echocardiographic inferior vena cava measurement
Description: Patients will be place in supine position. view: subcostal view, importantly supine is standard position for IVC measurement, the IVC is larger in the right lateral decubitus position and vice versa, alternatively directly through a transhepatic approach. Measures will be performed in the two dimensional mode close to the hepatic vein (1 - 3cm from the IVC connection to the right atrium). The IVC will be measured by MM-Mode manually and with the automated mode (both measures will be recorded. In the manual mode this measure requires concurrent utilization of M-Mode and two dimensional mode
Study NCT05559697 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sponsor incisional negative pressure wound therapy device and dressing
Description: A sponsor incisional dressing placed on the knee and connected to a sponsor disposable negative pressure therapy device
Study NCT05559697 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care incisional negative pressure wound therapy system
Description: The control incisional negative pressure wound therapy system represents the standard of care system and market leader. It consists of a disposable negative pressure therapy device and incisional dressing.
Study NCT06430515 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intratumoral Injection of Chemotherapy
Description: This project intends to investigate the clinical efficacy of intra-tumoural injection of chemotherapeutic agents (e.g. cisplatin, oxaliplatin, etc.)via fine needle aspiration guided by CT or ultrasound in patients with advanced solid cancers to validate the safety and efficacy.
Study NCT05673525 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter Aortic Valve Implantation (KOKA-VALVE)
Description: Transcatheter Aortic Valve Implantation
Study NCT04650425 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive tasks
Description: Patients will perform the coffee-tea task and the virtual T-maze task, both in the acute and chronic phase after stroke.
Study NCT05327764 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Work to rest cycles of 40:20 minutes
Description: Walking in a hot environment for 2 hours with repeated 40 minutes of work and 20 minutes of rest
Study NCT05327764 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Work to rest cycles of 20:10 minutes
Description: Walking in a hot environment for 2 hours with repeated 20 minutes of work and 10 minutes of rest
Study NCT05533710 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: erector spinae plane block
Description: Patients will receive ESB. In the lateral decubitus, after skin sterilization, ESP block will be performed at the level of T9
Study NCT05533710 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: transversus abdominis plane block
Description: patients will receive TAP block in supine position after skin sterilization, TAP block will be performed between internal oblique and transversus abdominis muscles
Study NCT05231707 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A couples-focused intervention for HIV prevention and care in South Africa
Description: From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing (intervention arm) or an attention matched control.
Study NCT05231707 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A couples-focused intervention for HIV prevention and care in South Africa
Description: From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing (intervention arm) or an attention matched control.
Study NCT05945303 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coronary Artery Bypass Grafting surgery
Description: Assessing the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using ultrasonography of the internal jugular vein for assessment of vessel distensibilty in relation to stroke volume variation (SVV) measured by electrical cardiometry.
Study NCT04857411 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peers LEAD plus HLWD
Description: Combined Peers LEAD and Healthy Living with Diabetes is a culturally-appropriate program to increase medication adherence
Study NCT06543927 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: serum creatinine
Description: Detection of renal impairment in patients receiving anticoagulants
Study NCT06543927 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: INR
Description: Detection of bleeding in patients with choronic kidney disease receiving anticoagulants
Study NCT05835583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The theory based integrated program
Description: The theory-based integrated program is administered by a nurse trained in motivational interviewing.In the 12-hour intervention, this program uses motivational interviewing skills to increase the patient's attitude towards medication, enhance the support of significant others around them, and increase the patient's control over their own behavior.
Study NCT04669366 — intervention group
Intervention type: DRUG
Intervention: sunitinib
Description: As provided in real world
Study NCT04669366 — intervention group
Intervention type: DRUG
Intervention: axitinib
Description: As provided in real world
Study NCT06264258 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DVx-T1D™ app
Description: The intervention group will be introduced to the DVx-T1D™ app and the participants will go home with the tablets that has the game installed. Participants will be asked to play the game for 20 mins or more daily. The aim of the app is to impart good behavioral changes in children with T1D in terms of diabetes education, on how to treat a low or a high blood sugar event and make healthy eating choices.
Study NCT05539040 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Right Atrial ganglionated plexus ablation
Description: A 3D electroanatomic map of the right atrium will be made. During sinus rhythm, the ablation catheter will be positioned at a spot to test with HFS. The right atrium will be paced at a fixed rate, for up to four beats to ensure that there is no ventricular capture then a short burst of HFS will be synchronized to each paced stimulus for up to 15 trains. This will be performed using a custom-built GP stimulator that has been validated for reproducibility against Grass Stimulator (AstroMed).~All Sites will be marked on the 3D map and the positive sites will be ablated at the end of the mapping. If the patient converts to AF, then DC cardioversion will be performed. If mapping in sinus rhythm is not feasible, HFS will be performed continuously for several seconds to identify atrioventricular dissociating GPs (AVD-GPs).~Every ablated GP site will be re-tested with HFS at the end of the procedure until they are all rendered non-functional.
Study NCT05539040 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Holter Monitor
Description: 48 hour Holter monitors will be performed post procedure to monitor for recurrence of AF.~These will be performed at 3, 6, 9, 12 months
Study NCT05539040 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Holter Monitor
Description: 48 hour Holter monitors will be performed post procedure to monitor for recurrence of AF.~These will be performed at 3, 6, 9, 12 months
Study NCT05940805 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
Description: 1. Low-frequency transcranial electrical stimulation (2/100 Hz) applied through 0.3-mm-diameter and 40-mm-long needles placed subcutaneously on the scalp at the projection of Penfield's motor homunculus and sensory and frontal supplementary motor associative areas.~2. Paraspinous block at the levels of the C5, C6 and C7 vertebrae concordant with spasticity laterality.~3. Dry needling of spastic upper limb muscles, as identified through a thorough physical examination, using 0.3-mm-diameter and 40-mm-long needles.~4. Muscular functional electrical stimulation (FES) in the antagonists of the upper limb muscles with spasticity with the following parameters: 20-Hz frequency, 300-µs pulse width, zero-second ramp time, 5-second stimulation time, and 5-second resting time.
Study NCT05940805 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: SHAM Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
Description: For simulation of transcranial electrical stimulation and FES, electrodes were placed on the scalp and in the upper extremity muscles and were connected to a device similar to the real electric current generator. This device did not transmit any electric current but had blinking lights and produced sound to provide the subjects visual and auditory feedback. To simulate dry needling and paraspinous block, retractile needles were used.
Study NCT04951791 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SMOFlipid
Description: will receive intravenous infusion of 2ml\\kg of smoflipid 20%, in the internal jugular vein 10 minutes before removal of aortic cross clamp in a constant speed
Study NCT04951791 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline 0.9%
Description: will receive intravenous infusion of 2ml\\kg of normal saline 0.9%, in the internal jugular vein 10 minutes before removal of aortic cross clamp in a constant speed.
Study NCT05539040 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary vein isolation
Description: Transseptal puncture for access into the left atrium will be guided by TOE and fluoroscopy.~ACT will be maintained at 300s with heparin. A 3D electroanatomic map of the left atrium will be created and all PVs will be identified. Touch-up radiofrequency ablation will be performed at electrical gaps around the reconnected PVs until complete PVI is achieved.
Study NCT05539040 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary vein isolation
Description: Transseptal puncture for access into the left atrium will be guided by TOE and fluoroscopy.~ACT will be maintained at 300s with heparin. A 3D electroanatomic map of the left atrium will be created and all PVs will be identified. Touch-up radiofrequency ablation will be performed at electrical gaps around the reconnected PVs until complete PVI is achieved.
Study NCT05539040 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Right cavo-tricuspid and left roof linear ablation
Description: CONTROL ARM (Redo-PVI) only: If all Pulmonary veins are isolated at the start of the procedure, the operator will be allowed to perform a right cavo-tricuspid and left roof linear ablation.
Study NCT05539040 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Personal ECG recordings
Description: All patients will be provided with an AliveCor KardiaMobile-6L ECG recorder. The device will continue to be used within its CE-marked and NICE-approved purpose. Patients will be asked to take a daily recording from this, once the blanking period is over, in addition to taking a recording if symptomatic. Patients will submit this to the connected care team at Hammersmith Hospital via a secure NHS.net email address, who will assess the recordings both for the study and clinical purposes.
Study NCT05604963 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Total Thyroidectomy
Description: Total Thyroidectomy - surgical removal of entire thyroid gland
Study NCT05604963 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hemithyroidectomy
Description: Hemithyroidectomy - surgical removal of partial thyroid gland
Study NCT05618418 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT05133219 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Occupational Therapy
Description: Occupational therapy is the only profession that helps people across the lifespan to do the things they want and need to do through the therapeutic use of daily activities (occupations). Occupational therapy practitioners enable people of all ages to live life to its fullest by helping them promote health, and prevent-or live better with-injury, illness, or disability.
Study NCT05539040 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Personal ECG recordings
Description: All patients will be provided with an AliveCor KardiaMobile-6L ECG recorder. The device will continue to be used within its CE-marked and NICE-approved purpose. Patients will be asked to take a daily recording from this, once the blanking period is over, in addition to taking a recording if symptomatic. Patients will submit this to the connected care team at Hammersmith Hospital via a secure NHS.net email address, who will assess the recordings both for the study and clinical purposes.
Study NCT05539040 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality of life questionnaire
Description: A Quality of life questionnaire will be performed at baseline, 6 and 12 months to assess the effect of the procedures on patients quality of life.
Study NCT05539040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality of life questionnaire
Description: A Quality of life questionnaire will be performed at baseline, 6 and 12 months to assess the effect of the procedures on patients quality of life.
Study NCT06387992 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Three-dimensional dental acquisition
Description: Consultation with a trained nurse who will perform a three-dimensional dental acquisition using a 3D intraoral camera
Study NCT05061498 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Additional Pacing maneuvers
Description: In order to determine the optimal setting for pacemapping in all participants additional pacing maneuvers (output and cycle length) are performed
Study NCT04851756 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRet
Description: In prone position, subjects will get a 7 min preparation massage with CRet on resistive mode (80-100W), on the lumbar area, followed by a 5 min preparation massage with CRet on resistive mode (100-120 W) on the hamstrings. Then a 5 min Functional Massage (F.M) with passive anckle dorsiflexion and CRet on resistive mode (110-120 W) will be performed on the gastrocnemius medialis and lateralis, followed by a 4 min F.M with CRet on capacitive mode (180-250VA) on the mentioned area. In supine position, a 5 min F.M with passive knee flexion and CRet on resistive mode (110-140W) will be performed on the rectus femoris, followed by a 4 min F.M with passive knee flexion and CRet on capacitive mode (180-250VA) on the mentioned area. A physiotherapist will monitor the temperature of the patient's treated area every 2 minutes.
Study NCT04851756 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham CRet
Description: In prone position, subjects will get a 7 min preparation massage with CRet on resistive mode (0 W), on the lumbar area, followed by a 5 min preparation massage with CRet on resistive mode (0 W) on the hamstrings. Then a 5 min Functional Massage (F.M) with passive anckle dorsiflexion and CRet on resistive mode (0 W) will be performed on the gastrocnemius medialis and lateralis, followed by a 4 min FM with CRet on capacitive mode (0 VA) on the mentioned area. In supine position, a 5 min F.M with passive knee flexion and CRet on resistive mode (0W) will be performed on the rectus femoris, followed by a 4 min F.M with passive knee flexion and CRet on capacitive mode (0VA) on the mentioned area.~A physiotherapist will monitor the temperature of the patient's treated area every 2 minutes.
Study NCT05485324 — intervention group
Intervention type: OTHER
Intervention: visual analog scale
Description: Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury.
Study NCT06198556 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-1167 tablets; rifampicin
Description: HRS-1167 tablets single oral dose of HRS-1167 or co-administered with rifampicin.
Study NCT02994498 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCB-BO1301
Description: 1, 2, or 3 capsules, three times a day, oral, at most 48 weeks
Study NCT05017532 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The program Remédiation Cognitive de la Cognition Sociale en Schizophrénie (RC2S+)
Description: The program Remédiation Cognitive de la Cognition Sociale en Schizophrénie (RC2S+) is a personalized CR treatment targeting social cognition (e.g. theory of mind, emotion recognition) using virtual reality to emulate daily social interactions
Study NCT06035848 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Association of the components of metabolic derangement and paracentesis.
Description: In the intervention group were determined:~1. Components of metabolic derangement~2. Paracentesis. Determination of surgery: 3 positive points of the components of the metabolic derangement and a positive paracentesis.~The components of the metabolic derangement are the 7 parameters described by Tepas: positive blood culture, metabolic acidosis, neutropenia, bandemia, thrombocytopenia, hyponatremia and hypotension, being considered positive when 3 or more parameters are present.~Paracentesis was considered positive according to Kosloske's criteria: obtaining more than 0.5ml of serohematic fluid, Gram-positive fluid and obtaining fecal material.~Both groups had the same pre, trans and postoperative care.
Study NCT06035848 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Bell's criteria: pneumoperitoneum
Description: In the control group, the surgery was determined according to Bell's criteria, in the presence of radiographic pneumoperitoneum as an absolute indication for surgery.
Study NCT05717023 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online guided self-help intervention for sexual distress following sexual assault
Description: 4 Sessions of guided self-help will be shared with the participants. These will be in the form of handout and video recordings that participant access through Qualtrics. The intervention is based on research on sexual trauma, psychosexual difficulties and materials developed by Bart's NHS Foundation Trust Sexual Wellbeing Service. It has been made in collaboration with clinicians within the service, experts by experience and the chief investigator.Within the document there are scripts for each session which are read out in the video recordings. The handouts depict the visual images for the video and the materials provided to participant.