AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05436067 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vestibular rehabilitation app
Description: Delivery of vestibular rehabilitation through an app on a tablet or other portable device. The app takes patients through their rehabilitation session that has been prescribed by a clinician. Exercises are presented in the forms of games that are controlled by head or torso motion via a motion sensor that is placed on that body part. Data on the motion of the patient are calculated from sensor data and sent over the cloud for the clinician to access remotely.
Study NCT04888559 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Breakfast product: Whole grain
Description: This intervention is a whole grain-based breakfast product containing oats and barley.
Study NCT04888559 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Breakfast product: Reference
Description: This intervention is a rice-based breakfast product.
Study NCT04881019 — intervention group
Intervention type: DEVICE
Intervention: Continuous glucose monitoring
Description: Continuous monitoring of blood sugar over a 10-day period.
Study NCT05911243 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05869734 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep health promotion
Description: We will provide sleep hygiene related adjustments in the intervention group A; and brief behavioral treatment for insomnia (BBTI) in the intervention group B.
Study NCT05869734 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Urologic health promotion
Description: We will provide information related to urologic health promotion in three groups (2 experimental groups and 1 comparison group).
Study NCT05869734 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Urologic health promotion
Description: We will provide information related to urologic health promotion in three groups (2 experimental groups and 1 comparison group).
Study NCT05869734 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Pelvic floor muscle training
Description: We will provide information related to pelvic floor muscle training in three groups (2 experimental groups and 1 comparison group).
Study NCT05869734 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic floor muscle training
Description: We will provide information related to pelvic floor muscle training in three groups (2 experimental groups and 1 comparison group).
Study NCT05948813 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TY-9591
Description: The dose of TY-9591 tablet is 160 mg once daily. A cycle of treatment is defined as 21 days of once daily treatment until meet the of discontinuation criteria.
Study NCT05948813 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Osimertinib
Description: The dose of Osimertinib is 80 mg once daily. A cycle of treatment is defined as 21 days of once daily treatment until meet the of discontinuation criteria.
Study NCT04658498 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Procedure: Usual Care (UC)
Description: Intermittent spontaneous breathing periods
Study NCT04658498 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Procedure: UC + HI-IMT
Description: UC + Supervised daily sessions of training including 4 sets of 6-10 full vital capacity breaths against an external load using a tapered flow resistive device (POWERbreathe KH2, HaB International, UK). The maximum tolerable resistance allowing patients to inhale at least 70% of their inspiratory vital capacity will be chosen and progressively increased throughout the training period.
Study NCT04658498 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Procedure: UC + LI-IMT (sham IMT)
Description: UC + superrvised daily sessions of training including 4 sets of 6-10 breaths at the lowest external imposable load with the tapered flow resistive device (POWERbreathe KH2, HaB International, UK) (i.e. 3 cmH2O).
Study NCT06375694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Herbiotics Oral + Ent Probiotic
Description: Chewable Tablets containing Lactobacillus species.
Study NCT06375694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Honest Placebo Pills by Zeebo
Study NCT06660706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-domain intervention
Description: Each session comprises of 45 minutes physical fitness activities targeting on muscle strength, balance, and flexibility; 1-hour cognitive training primarily on reasoning and memory exercises; and 15-minute for nutritional advices based on national diet guidelines for older adults
Study NCT06659731 — intervention group
Intervention type: OTHER
Intervention: Quantitative Sensory testing (QST)
Description: The QST protocol (Rolke et al., 2006; Blankenburg et al., 2010), implies the administration of 7 short sensory test in order to measure up to 13 parameters, which can be grouped as follows: thermal detection thresholds for the perception of cold, warm and paradoxical heat sensations, thermal pain thresholds for cold and hot stimuli, mechanical detection thresholds for touch and vibration, mechanical pain thresholds and sensitivity for pinprick and blunt pressure, vibration detection threshold and pressure pain threshold.
Study NCT06659731 — intervention group
Intervention type: OTHER
Intervention: EEG
Description: EEG recording at rest and while receiving heat stimuli to study cortical processing of salient thermal stimuli. Up to 30 painful thermal stimuli, will be delivered to the patients' hand dorsum in order to register contact heat evoked potentials (CHEPs).
Study NCT04813406 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib + Sintilimab
Description: Anlotinib: 1 capsule (10mg) once a day, d1-d14 per cycle, 3 weeks for a treatment cycle.~Sintilimab: 200 mg/time, intravenous injection, every 3 weeks is one cycle.
Study NCT05682950 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: online adaptive radiotherapy
Description: CTV covers pelvis.
Study NCT04922242 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Welch Emotional Connection Screen for Neonatal Intensive Care Unit
Description: The Welch Emotional Connection Screen (WECS) is an investigational developmental screening tool, developed to rate the quality of the emotional connection that formed between mother and child. The screen is administered in 2-3 minutes by observing a mother and child interact, and requires the rater to critically assess 4 sub-domains of emotional connection. The NICU WECS is a clinical tool adapted for use with neonates in the NICU. Reliability of NICU staff WECS scoring will be calculated via intra-class correlations with key scores. The WECS is scored on intervals of 0.5, with a minimum of 1 (rarely--low level of connection) and maximum of 3 (mostly--high connection). Scores are used to determine the level of need for intervention.
Study NCT04959786 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin,ribavirin ,nitazoxanide and zinc
Description: oral intake of the 3 drugs ivermectin ,ribavirin and nitazoxanide plus zinc
Study NCT06482138 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Biopsy and Cytobrush
Description: Collection of olfactory cleft biopsies and cytobrushes
Study NCT05786976 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lotion BNO 3732
Description: Crem body lotion twice daily
Study NCT05786976 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Body Lotion Benchmark product
Description: Crem body lotion twice daily
Study NCT06661382 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Infiltrative treatment with CB-PRP
Description: Injection of CB-PRP or placebo into the vulvar site. Three treatments are planned four weeks apart. Three and six months after the last treatment with CB-PRP/ placebo each participant will be re-evaluated by vulvoscopy and biopsy, and will be given validated questionnaires to assess satisfaction, symptoms, and quality of life, psychological state, and sexual function.
Study NCT06661382 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Infiltrative treatment with CB-PRP
Description: Injection of CB-PRP or placebo into the vulvar site. Three treatments are planned four weeks apart. Three and six months after the last treatment with CB-PRP/ placebo each participant will be re-evaluated by vulvoscopy and biopsy, and will be given validated questionnaires to assess satisfaction, symptoms, and quality of life, psychological state, and sexual function.
Study NCT06659081 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: socket shield technique
Description: partial extraction therapy : sectioning the root and keeping part of it in contact with labial plate of bone
Study NCT06659081 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: subepithelial connective tissue graft
Description: A connective tissue graft harvesting from maxillary tuberosity area
Study NCT06659081 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: implant placement
Description: implant placement
Study NCT05422534 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CoQ10
Description: Participants will receive 1800 mg/day for 12 weeks
Study NCT05422534 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive placebo or CoQ10/day for 12 weeks
Study NCT05422534 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HB-HIIT
Description: Participants will be performed on non dialysis days. It will be video supervised exercise sessions with self directed exercises using pre-recorded bodyweight and strength exercise videos.
Study NCT05422534 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: HB-HIIT
Description: Participants will be performed on non dialysis days. It will be video supervised exercise sessions with self directed exercises using pre-recorded bodyweight and strength exercise videos.
Study NCT05422534 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Observational
Description: Participant regular activities
Study NCT05422534 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Observational
Description: Participant regular activities
Study NCT06661005 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitrous oxide
Description: The Nitrous oxide group will receive instructions to arrive at clinic 30 minutes before her procedure in order to sign consent forms. She will not be given instructions to remain NPO and will not be required to have someone bring her to and from the appointment. No IV will be placed. Anesthesia induction will be done by an anesthesiologist with a nitrous oxygen mixture at a 70:30 ratio
Study NCT06661005 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IV Sedation
Description: Anesthesia induction will be done by an anesthesiologist with propofol per standard protocol. A pulse oximeter will be placed and oxygen will be administered through a nasal cannula and the patient will be instructed to breath.
Study NCT06658145 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vnotes surgery using fully visualised surgical instruments
Description: Vnotes surgery using fully visualised surgical instruments
Study NCT06658145 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vnotes surgery using traditional surgical instruments
Description: Vnotes surgery using traditional surgical instruments
Study NCT06542978 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 40Hz stimulation
Description: Exogenous 40HZ stimulation is a physical intervention that can drive oscillations in the gamma range, and the oscillations and pulses caused at the corresponding frequency can lead to a significant reduction in β-amyloid, reverse tau hyperphosphorylation, and thereby improve the cognitive function of patients.
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nirmatrelvir/ritonavir (e.g. PAXLOVID™)
Description: Nirmatrelvir 300mg BD for 5/7 Ritonavir 100mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitazoxanide
Description: Nitazoxanide 1.5g BD 7/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Molnupiravir and nirmatrelvir/ritonavir (e.g. PAXLOVID™)
Description: Molnupiravir 800mg BD for 5/7, Nirmatrelvir 300mg BD for 5/7, Ritonavir 100mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxychloroquine
Description: Hydroxychloroquine 400mg D0 BD and 400MG OD for a further 6/7
Study NCT05041907 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: No treatment
Description: No treatment (except antipyretics- paracetamol)
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monoclonal antibodies
Description: Monoclonal antibodies: 300mg tixagevimab/ 300 mg cilgavimab given once on D0
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluoxetine
Description: Fluoxetine 40mg OD for 7/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Molnupiravir
Description: Molnupiravir 800mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotrovimab
Description: Sotrovimab 500mg given once on D0
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ensitrelvir
Description: Ensitrelvir 375mg OD D0 and 125mg OD for a further 4/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Monoclonal antibodies
Description: Monoclonal antibodies: 600mg casirivimab/ 600mg imdevimab given once on D0
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Favipiravir
Description: Favipiravir 1800mg BD D0 and 800mg BD for a further 6/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin
Description: Ivermectin 600micrograms/kg/day for 7/7.
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remdesivir
Description: Remdesivir 200mg D0 and 100mg for a further 4/7.
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atilotrelvir/ritonavir
Description: Atilotrelvir 150mg BD for 5/7 Ritonavir 100mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Metformin 500mg TDS 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir/ritonavir
Description: Nirmatrelvir 300mg BD for 5/7 Ritonavir 50mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir/ritonavir
Description: Nirmatrelvir 150mg BD for 5/7 Ritonavir 50mg BD for 5/7
Study NCT05041907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirmatrelvir
Description: Nirmatrelvir 300mg BD for 5/7
Study NCT06615661 — intervention group
Intervention type: DEVICE
Intervention: C-Rex Instrument
Description: The C-Rex Instrument is a manual ophthalmic surgical instrument used for ab interno goniotomy and inner wall trabeculotomy.
Study NCT05396222 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3D-printed custom-made non-rigid biomimetic implant
Description: We developed a 3D printed, custom-made, biomimetic prosthesis, with non-rigid structure, which has been tested in biomechanical study and porcine model, showing good bone formation and less stiffness as well. Therefore, we proposed a prospective clinical study to investigate safety, subsidence, and fusion of this prosthesis.
Study NCT04922242 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NICU WECS Training
Description: WECS Training is an educational module consisting of an introduction of the concepts of emotional connection and autonomic co-regulation as studied by The Nurture Science Program, as well as an illustration of how these experiential constructs differ from traditional care plans that focus on educating parents to encourage bonding as opposed to autonomic emotional connection within the NICU. An introduction to the domains of the WECS screen as well as illustrations of these domains through video will augment the training designed for NICU staff.
Study NCT05779761 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online, Self-Directed Attention Skills Training with Coaching Support
Description: The initial set of modules focus on psychoeducation about distress, the impact that cognitions/behaviors/emotions have on recent situations, and self-monitoring of worry/rumination/self-criticism. The next set of modules focus on the development of attention skills that help regulate one's emotional experience (i.e., recognizing emotions when they are happening, identifying the meaning of a given emotion experience, soothing oneself in the context of negative emotional experiences). All modules will be online and self-directed. An internet-based online platform will be used to promote engagement with and increase accessibility to between-session skills practice and treatment-related activities (e.g., self-monitoring, worksheets). Brief, weekly coaching support (from a trained, masters-level student) will be provided to promote engagement and to help clarify concepts.
Study NCT05779761 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support
Description: The initial set of modules focus on psychoeducation about distress, the impact that cognitions/behaviors/emotions have on recent situations, and self-monitoring of worry/rumination/self-criticism. The next set of modules focus on the development of attention and reflective thinking skills that help regulate one's emotional experience (i.e., recognizing emotions when they are happening, identifying the meaning of a given emotion experience, soothing oneself in the context of negative emotional experiences). All modules will be online and self-directed. An internet-based online platform will be used to promote engagement with and increase accessibility to between-session skills practice and treatment-related activities (e.g., self-monitoring, worksheets). Brief, weekly coaching support (from a trained, masters-level student) will be provided to promote engagement and to help clarify concepts.
Study NCT05779761 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online, Self-Directed Health & Wellness Education Training with Coaching Support
Description: The initial set of modules focus on psychoeducation about stress, the impact that stress has on one's life, and self-monitoring of stress. The next set of modules focus on sleep, time management, nutrition, and exercise. All modules will be online and self-directed. An internet-based online platform will be used to promote engagement with and increase accessibility to between-session skills practice and treatment-related activities (e.g., self-monitoring, worksheets). Brief, weekly coaching support (from a trained, masters-level student) will be provided to promote engagement and to help clarify concepts.
Study NCT06319430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: robots
Description: LEGO robots with adaptation according to child's age and developmental skills.
Study NCT06319430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional
Description: A pack of conventional play tools consists of dolls, teddy bears, miniature wild animals, and small cars. All are available, and the child can choose to play with them.
Study NCT06500234 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Megestrol Acetate and olanzapine
Description: megestrol acetate, 160 mg, oral everyday; olanzapine 2.5 mg, oral everyday
Study NCT06500234 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Starch powder 50 mg
Description: Starch powder 50 mg, oral, everyday
Study NCT06013865 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Empagliflozin
Description: SGLT2 Inhibitor
Study NCT05238441 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SCTV01E
Description: D0; intramuscular injection
Study NCT05238441 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty
Description: D0; intramuscular injection
Study NCT05238441 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: SCTV01E
Description: D180; intramuscular injection
Study NCT05238441 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SCTV01E
Description: D180; intramuscular injection
Study NCT05238441 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty
Description: D180; intramuscular injection
Study NCT05711953 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Egyfil Pain Lotion
Description: Egyfil is a cosmetic product to be applied to intact skin, useful to attenuate muscolar pain and stiffness, with a novel topical formulation containing hyaluronic acid, SH-Polypeptide-6 and SH-Oligopeptide-1.~The presence of sodium hyaluronate and peptides mixture promotes the pain alleviating activity and soothing properties of the product.
Study NCT04739670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab is a monoclonal antibody of IgG1 isotype PD-L1. It is used across a number of tumour types, both as a single-agent and in combination with other therapies such as chemotherapy.
Study NCT04739670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab is a monoclonal antibody to vascular endothelial growth factor (VEGF) which exerts its effect by inhibiting angiogenesis, a critical component of tumour growth and metastasis.
Study NCT04739670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Gemcitabine is a type of chemotherapy drug