AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05913427 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Etoposide, doxorubicin, cisplatin and Mitotane plus Placebo
Description: EDP will be administered at the following doses: doxorubicin 40 mg/m2 on day 1, etoposide 100 mg/m2 days 2-4, cisplatin 40 mg/m2 days 3-4, every 28 days. Placebo 160 mg tablets will be developed by the CDMO to have the same appearance and taste as the tablet containing the active drug.
Study NCT06538181 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pacritinib
Description: Starting dose is 200 mg twice per day by mouth. Dose level -1 is 100 mg twice per day by mouth.
Study NCT05997550 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pursed Lip Breathing Exercise
Description: Pursed Lip Breathing Exercise for The COPD
Study NCT05997550 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Laughter Therapy
Description: Laughter Therapy for the COPD
Study NCT05997550 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: the control group.
Description: Attention-match training is given to the patients in the control group.
Study NCT05147935 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Palliative Care Consultation
Description: In person or telehealth clinic visit with palliative care physician or nurse practitioner
Study NCT06340516 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Plasma NT-proBNP
Description: Replacement of measurement of plasma NT-proBNP instead of ECHO/MUGA at 6 months and 12 months of trastuzumab treatment to assess cardiotoxicity
Study NCT05592262 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2554
Description: On an empty stomach - after meals
Study NCT05592262 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR2554
Description: After meals - on an empty stomach
Study NCT06428786 — intervention group
Intervention type: OTHER
Intervention: Female Sexual Function Index
Description: As part of the study, data on the socio-demographic characteristics of the individuals is collected by means of personal interviews using a questionnaire. The results of laboratory tests required for the diagnosis of PCOS will be taken from hospital records. The Female Sexual Function Index (FSFI), the Beck Depression Inventory and the KF-36 quality of life assessment form will be completed in person and the total scores will be analyzed taking into account four different PCOS phenotypes.
Study NCT06227338 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine green
Description: Indocyanine green dye (Diagnostic Green) will be diluted with sterile water and a specific dose-arm (0.125 mg/kg, 0.25 mg/kg, 05 mg/kg, 1 mg/kg, and 2 mg/kg) will be administrated by slow intravenous injection by peripheral venous catheter:~* at induction anaesthesia of the surgical procedure (0.125 mg/kg or 0.25mg/kg), or~* in the hospital room 24 hours before the breast surgery (05 mg/kg, or 1 mg/kg, or 2 mg/kg).
Study NCT05680012 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Gluten containing snack bar
Description: Ingest snack bars containing 3 grams of gluten every day for 6 weeks.
Study NCT06104657 — intervention group
Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study NCT05735847 — intervention group
Intervention type: PROCEDURE
Intervention: Total Knee Arthroplasty (TKA)
Description: The choice between TKA and UKA is based on the radiological presentation of the knee KOA on an x-ray. A surgery with TKA involves the replacement of both the medial and lateral compartments of the knee.
Study NCT05735847 — intervention group
Intervention type: PROCEDURE
Intervention: Unicompartmental Knee Arthroplasty (UKA)
Description: The choice between TKA and UKA is based on the radiological presentation of the knee KOA on an x-ray. A surgery with UKA involves the replacement of one compartment.
Study NCT06277817 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: expiratory rib cage compression
Description: Expiratory rib cage compression: The hands are placed on the lower third of the rib cage. During expiration, the end and sides of the patients' rib cage are gradually compressed with the hands.At the end of expiration, compression is released from the thorax to allow patients to take a free inspiration. After each compression, the patient is allowed to perform 3 breathing cycles.Expiratory rib cage compression is applied for 5 minutes.
Study NCT06277817 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: percussion vibration
Description: Percussion :Percussion is performed 3-5 times on each area from a height of approximately 10 cm with the domed hand. . It starts from the right and left lower lobes and goes up.Vibration:The hand is firmly/strongly placed on the application area. The arm and shoulder are stretched and the fingers are gently vibrated or shaken gently. While the patient is exhaling, vibration is performed 3-5 times in each area, starting from the right and left lower lobes.
Study NCT05161403 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid
Description: Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process.~use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
Study NCT05161403 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hyaluronic acid
Description: Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process.~use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
Study NCT05161403 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: honey
Description: Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process.~Use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
Study NCT05161403 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: honey
Description: Wound healing is still a clinical challenge especially in patients who undergo several tooth extractions under general anesthesia or those undergoing major surgeries or those with systemic conditions that disrupt the wound healing process.~Use of this natural substance is a simple and cost-effective technique and is easily tolerated by children.
Study NCT05701618 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychologically Informed Education Video Series
Description: A short three video series (5-8.5 minutes each) provides psychologically-informed education at an age-appropriate level to address kinesiophobia, pain catastrophizing, and fear-avoidance beliefs.30 Participants will view the three-part education video series on an iPad at their first visit (video 1), one week (video 2), and three weeks (video 3).
Study NCT05701618 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Anatomy and biomedical education videos
Description: Participants in the control group will watch three videos equal in length to the psychologically-informed videos. The control videos will discuss anatomy of the lower extremity, basic instruction in proper lower extremity biomechanics, and simple lower extremity exercises. The control videos will provide no psychologically-informed education or positive reinforcement about the condition.
Study NCT06428513 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HCTP
Description: 10 weekly 1-on-1 30-minute tele-sessions via Zoom, delivered by a certified health coach. At baseline assessment including full medical history, medications, lifestyle practices, self-reported health status, psychosocial status, and other relevant information will be taken. At the first session, participants identify their health vision and 3-month health goals. At subsequent meetings, participants review their progress towards reaching the prior week's goals and identify goals for the next week. An individualized action plan will be formulated to help each participant achieve their goals. The action plan will focus on important lifestyle practices (physical activity/exercise training, correct nutrition, weight management, tobacco cessation, and stress management. Patients can request further health care advice felt necessary for their progress, and will be referred to health care professionals in the rehabilitation hospital that provide care for lung transplantation candidates.
Study NCT04376359 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: hyperbaric oxygen therapy
Description: Hyperbaric oxygen therapy is the patient put in airtight oxygen tank, by increasing the air pressure in the environment (1.5 to 3.0) under atmospheric pressure, to give 100% oxygen, the patient treatment time is approximately 60 minutes to 120 minutes in this way, can achieve the purpose of greatly increase the oxygen partial pressure in the organization, so as to achieve reverse brain edema, reduce lipid peroxidation, inhibiting leukocyte hyperactivity, rebuild the blood brain barrier.
Study NCT04846647 — intervention group
Intervention type: BEHAVIORAL
Intervention: unexplained hypophoshatemia
Description: Collection of additional blood volume (approximately 10 mL) during blood tests provided as part of the usual medical care.
Study NCT06602492 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lower nicotine e-liquid
Description: A 3% nicotine concentration eliquid.
Study NCT06602492 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Higher nicotine eliquid
Description: A 5% nicotine concentration eliquid.
Study NCT06616727 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNC109
Description: SNC-109 CAR-T Cells, first dose from 5×104 CAR+ T Cells, treatment follows the operation and the next dose would be deiced by SRC
Study NCT06553625 — intervention group
Intervention type: DEVICE
Intervention: Radiofrequency Ablation
Description: Radiofrequency Ablation used in the central nervous system (CNS) in functional neurosurgery
Study NCT05277155 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BEJO Red Ginger Extract
Description: BEJO Red Ginger Extract ingredients:~* Zingiber officinale var. rubrum (Rhizome extract) 80 mg~* Foeniculi vulgare Fructus (Fennel) 25 mg~* Menthae arvensis Folium (Mint) 5 mg~* Piper retrofractum Fructus (Javanese long pepper) 12.5 mg~* Honey 7500 mg
Study NCT05277155 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo composition: Substance without active ingredient
Study NCT06215898 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LSVT-BIG Group via Telerehabilitation
Description: An aerobic supervised exercise protocol was implemented four times a week for four weeks in LSVT-BIG Group via a Tele-rehabilitation model.
Study NCT04746612 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HH30134
Description: HH30134 administered orally on a continuous once daily(QD) in patients with advanced solid tumors
Study NCT06674135 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: biosimilar insulin glargine
Description: Switched to once daily injection of biosimilar insulin glargine via reusable pen and three mealtime bolus insulin injections of short-acting human insulin via needle and syringe
Study NCT06616467 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tummy Time for the prevention of childhood obesity
Description: A cognitive-behavioral intervention aimed at mothers of infants is presented that aims to increase the practice of TT and maintain a healthy weight in the infant, called \&#34;Tummy Time for the prevention of childhood obesity\&#34;, within the intervention modifiable variables are involved that directly impact the expected results such as: the knowledge and beliefs of the mothers, infant temperament, parental self-efficacy and self-efficacy for the practice of TT.~The intervention lasts 12 weeks from the first contact with the participants and consists of eight sessions broken down as follows: the first session is presented in a face-to-face format with expository, audiovisual and demonstrative means; sessions two, four, five and seven are provided through a text message with use WhatsApp® and the use of visual media. Sessions three, six and eight are delivered via telephone call with the aim of offering feedback on the doubts generated up to that point.
Study NCT06677931 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator:1565 non-ablative fractional laser combined with normal Saline
Description: Based on the patient's age, skin color, location of skin lesions, and Fitzpatrick skin type, adjust treatment parameters accordingly. The operator holds the treatment head, vertically applies parallel sweeps closely to the lesion area until the endpoint of slight skin redness is reached. After completion, apply normal Saline.
Study NCT06677931 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 1565 non-ablative fractional laser combined with umbilical cord mesenchymal stem cell-derived exosomes.
Description: Based on the patient's age, skin color, location of skin lesions, and Fitzpatrick skin type, adjust treatment parameters accordingly. The operator holds the treatment head, vertically applies parallel sweeps closely to the lesion area until the endpoint of slight skin redness is reached. After completion, apply exosomes.
Study NCT06679491 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance periodized training program (N-PF)
Description: This intervention consists of a 13-week structured resistance training program tailored to align with the natural menstrual cycle, focusing on intensified training during the follicular phase. Participants perform two resistance training sessions per week, each lasting 90 minutes, with intensity modulated based on the participant's menstrual phase.~Intensity Modulation:~Follicular Phase (Days 1-14): Training sessions are performed at a higher training load during both early and late follicular phases. The increased intensity leverages higher estrogen levels, which may support greater muscle strength and recovery during this phase.~Luteal Phase (Days 15-28): Training sessions are conducted at a lower training load during both early and late luteal phases to accommodate the hormonal shifts associated with elevated progesterone.
Study NCT06679491 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance peioridized training program (N-PL)
Description: This intervention consists of a 13-week structured resistance training program tailored to align with the natural menstrual cycle, focusing on intensified training during the luteal phase. Participants perform two resistance training sessions per week, each lasting 90 minutes, with intensity modulated according to the participant's menstrual phase.~Intensity Modulation:~Follicular Phase (Days 1-14): Training sessions are conducted at a lower training load during both early and late follicular phases to accommodate the hormonal environment of this phase.~Luteal Phase (Days 15-28): Training sessions are performed at a higher training load during both early and late luteal phases. The increased intensity leverages the hormonal environment associated with elevated progesterone, which may affect muscle endurance and neuromuscular adaptations during this phase.
Study NCT06679491 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Continuous resistance training program (C)
Description: This intervention consists of a 13-week structured resistance training program with a continuous training intensity maintained throughout the menstrual cycle. Participants perform two resistance training sessions per week, each lasting 90 minutes, with a consistent training load applied across all phases.~Intensity Modulation:~All Phases: Training sessions are conducted at a steady training load regardless of menstrual phase. This continuous approach is designed to provide a baseline for assessing neuromuscular adaptations without the influence of phase-specific intensity adjustments.
Study NCT06679491 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Continuous resistance training program (C)
Description: This intervention consists of a 13-week structured resistance training program with a continuous training intensity maintained throughout the menstrual cycle. Participants perform two resistance training sessions per week, each lasting 90 minutes, with a consistent training load applied across all phases.~Intensity Modulation:~All Phases: Training sessions are conducted at a steady training load regardless of menstrual phase. This continuous approach is designed to provide a baseline for assessing neuromuscular adaptations without the influence of phase-specific intensity adjustments.
Study NCT06677788 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Roflumilast 500 Mcg Oral Tablet
Description: Patients in this group received roflumilast 500 μg once daily for three months.
Study NCT06677788 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin E capsule
Description: vitamin E group or control group (n=24) which received vitamin E 1000 mg once daily
Study NCT05135624 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SP16 (6mg)
Description: SP16 will be administered as 2 concurrent, separate 2 mL s.c injections of 3mg/mL SP16
Study NCT05135624 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered as 2 concurrent, separate 2 mL s.c. injections of sterile water
Study NCT05444101 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful attention
Description: The Mindful attention treatment component consists of a breathing exercise and is operationalized as two sessions (1 hour each) delivered over two weeks, i.e., one session per week, with homework between sessions. Sessions will be delivered online.
Study NCT05444101 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Decentering
Description: The Decentering treatment component consists of a guided imagery exercise and is operationalized as two sessions (1 hour each) delivered over two weeks, i.e., one session per week, with homework between sessions. Sessions will be delivered online.
Study NCT05444101 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Values and committed action
Description: The Values and committed action treatment component consists of identification of personal values and committed action, and is operationalized as two sessions (1 hour each) delivered over two weeks, i.e., one session per week, with homework between sessions. Sessions will be delivered online.
Study NCT05072704 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sufentanil
Description: Pre-operative injection of sufentanil 10µg in 2ml of normal saline on induction of anesthesia + per-operative injection of sufentanil 5µg in 1ml of normal saline during the surgery if needed.
Study NCT05072704 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Pre-operative infusion of dexmedetomidine 1µg/kg in 100ml of normal saline before surgery + per-operative infusion of dexmedetomidine 0.4 µg/kg in 100ml of normal saline during the surgery if needed.
Study NCT04442113 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Pulmonary vein isolation plus ablation guided by novel STAR mapping™
Description: Catheter ablation for persistent AF consisting of pulmonary vein isolation plus additional ablation guided by the novel STAR mapping™ software on a computer device.
Study NCT04442113 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary vein isolation
Description: Catheter ablation for persistent AF consisting of pulmonary vein isolation (the standard treatment for AF)
Study NCT05802212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin intervention for 12 weeks
Description: PCOS patients were treated with metformin orally for 12 weeks, and various indicators related to fertility were observed.
Study NCT05886504 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Community-based psychiatric intervention
Description: intervention will take place in CBO offices instead of mental health department, medication will be given freely and psychiatric consultations will be free. Trained CBO members will provide individual and collective support including recall of appointments and tracing of those lost to follow-up, information on mental health, main psychiatric disorders, psychiatric medication, their potential side effects and expected benefits, contact with families and continuous support
Study NCT05412875 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Given usual care
Study NCT05412875 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Replacement
Description: Given JUUL
Study NCT05412875 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT05412875 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT04980157 — intervention group
Intervention type: BEHAVIORAL
Intervention: CARES-HCV
Description: CARES-HCV is an educational intervention to promote both hepatitis c screening and colorectal cancer screening among diverse baby boomers in the area.
Study NCT06465966 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iRAI
Description: Ionizing-radiation photo acoustic imaging (iRAI) is a method of collecting images from inside the body using acoustic (sound) waves. Researchers will collect iRAI during a participant's radiation treatments. Researchers will use this imaging to examine the delivery and dose of the radiation to the participant's prostate. Researchers will also compare the delivery and dose calculated from iRAI to the expected doses that were calculated from CT images which are done as standard of care.