AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05746949 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: oxygenization techniques
Description: to compare the effects of high-flow nasal oxygen and jet ventilation on oxygenation in patients who will receive general anesthesia for endolaryngeal surgery.
Study NCT06375902 — intervention group
Intervention type: BEHAVIORAL
Intervention: PragmaCom
Description: Cognitive behavioral intervention targeting the ability to understand metaphors
Study NCT06262230 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online Inclusive Companionship Intervention
Description: After prior intervention, professionals will conduct a lecture for ordinary children, which includes basic knowledge of ASD and communication skills with ASD children. These ordinary children will be paired with ASD children then. The entire intervention including 12 sessions will last for 3 months. Researchers will prepare a series of themes that the ASD children could choose, and the ordinary children need to ask their paired ASD children what activities they want to choose before each session. Then, they will carry out this entertainment online together through Tencent WeMeet. A researcher will supervise online at the same time and record the communication through instant video. The Researcher will turn off the video and sound throughout the process and will not intervene in the conversation between the ASD children and ordinary children except for special circumstances.
Study NCT05037734 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Persona Partial Knee System
Description: Unicompartmental Knee Replacement
Study NCT05698797 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hip strengthening exercises
Description: Hip abductor and external rotator strengthening exercises were performed for 4 weeks.
Study NCT05698797 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Proprioceptive training
Description: Proprioceptive training consisted of eight exercises was performed for 4 weeks.
Study NCT05698797 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: Conventional physical therapy included interferential therapy and two types of knee-strengthening exercises.
Study NCT05464810 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: Given PO
Study NCT05464810 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Letrozole
Description: Given PO
Study NCT05464810 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Simvastatin
Description: Given PO
Study NCT05485194 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Reducing dimensional changes following tooth extraction
Description: Use of a titanium bone screw for ridge preservation following tooth extraction
Study NCT05485194 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reducing dimensional changes following tooth extraction
Description: Use of a titanium bone screw for ridge preservation following tooth extraction
Study NCT06457373 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Demineralized Dentin Allograft
Description: 20 sockets are randomly allocated to receive the Demineralized Dentin Allograft (split-mouth study)
Study NCT06457373 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Demineralized Dentin Autograft
Description: 20 sockets are randomly allocated to receive the Demineralized Dentin Autograft (split-mouth study)
Study NCT00961558 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Varicocelectomy
Description: Varicocelectomy
Study NCT05352867 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 (LVRNA009) 50μg group
Description: 50μg/person
Study NCT05352867 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SARS-CoV-2 (LVRNA009) 100μg group
Description: 100μg/person
Study NCT05352867 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.5ml/person
Study NCT06395740 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enteral nutrtion
Description: enteral nutrition via nasogastric tube.
Study NCT06395740 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TPN
Description: of NPO strategy except for medications to be given via nasogastric tube till 14 days from day of stroke with fulfilment of nutrition requirement by parenteral route
Study NCT05778357 — intervention group
Intervention type: OTHER
Intervention: Group1
Description: 75 healthy infants were included. Neuromotor development was evaluated with the Denver II Developmental Screening Test and Alberta Infant motor scale.
Study NCT04402788 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atezolizumab
Description: Given IV
Study NCT04402788 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Given IV
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo blood and tissue collection
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood and tissue collection
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Computed Tomography
Description: Undergo CT
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Positron Emission Tomography
Description: Undergo PET
Study NCT06398951 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Two nare high flow nasal cannula
Description: Recently a new mode of high flow oxygen therapy has presented on the market where the prongs of high flow have different diameters .These two-nare size high flow nasal cannula are capable of delivering gases at a flow rate of 15-50 L/min, similar to the conventional HFNP but the difference in the diameters provide different levels of positive pressure as compared to conventional HFNP.
Study NCT06398951 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Two nare high flow nasal cannula
Description: Recently a new mode of high flow oxygen therapy has presented on the market where the prongs of high flow have different diameters .These two-nare size high flow nasal cannula are capable of delivering gases at a flow rate of 15-50 L/min, similar to the conventional HFNP but the difference in the diameters provide different levels of positive pressure as compared to conventional HFNP.
Study NCT04402788 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography
Description: Undergo PET
Study NCT04402788 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo radiation therapy
Study NCT06117904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MEBO ointment
Description: This group included twenty-five patients given Mebo ointment in combination with the symptomatic therapy 3 times daily for 7 weeks
Study NCT06117904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Symptomatic treatment only
Description: This group included twenty-five patients given symptomatic therapy 3 times daily for 7 weeks.~These therapies included anti-fungal agents (Miconaz oral gel), topical anesthetics and anti-inflammatory drugs (BBC oral spray), topical analgesic gel (Oracure gel), sodium bicarbonate mouthwash (Alkamisr sachets).
Study NCT06117904 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Symptomatic treatment only
Description: This group included twenty-five patients given symptomatic therapy 3 times daily for 7 weeks.~These therapies included anti-fungal agents (Miconaz oral gel), topical anesthetics and anti-inflammatory drugs (BBC oral spray), topical analgesic gel (Oracure gel), sodium bicarbonate mouthwash (Alkamisr sachets).
Study NCT06344130 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Radiation therapy will be administered via a linear accelerator using 6 megavoltage (MV) photons or greater.
Study NCT05197309 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Metabolic Diet
Description: Metabolic Diet includes increasing the amount of foods high in fat and decreasing the amount of foods that may cause increased flux in blood glucose levels. Food logs and ketone logs will be reviewed weekly during the 8 weeks of the intervention.
Study NCT04705350 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zampilimab
Description: Participants will receive a single intravenous dose of zampilimab at a pre-specified time point.
Study NCT06118515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letermovir
Description: Letermovir is a novel inhibitor targeting the cytomegalovirus (CMV) viral enzyme, effectively disrupting the production of additional CMV virions. Letermovir has demonstrated potent, selective, and reversible inhibition of CMV activity in preclinical studies.
Study NCT04824105 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: A repetitive Transcranial Magnetic Stimulation (rTMS) MagVenture MagPro TMS System will be used to deliver intermittent theta burst to ventromedial prefrontal cortex, and continuous theta burst to pre-supplementary motor area.
Study NCT04705350 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive matching placebo at a pre-specified time point to maintain the blinding.
Study NCT04822441 — intervention group
Intervention type: OTHER
Intervention: data collection
Description: Ultrasound follow-up maternal dengue serology PCR (Polymerase Chain Reaction) and dengue serology of the umbilical cord
Study NCT06305091 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Health survey for physical and mental health comorbidities, epigenetic marker and heavy metals in blood and urine samples
Description: Health survey for physical and mental health comorbidities, epigenetic marker and heavy metals in blood and urine samples
Study NCT05637957 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active transcranial direct current stimulation
Description: Device: 20 minutes of up to 2.0 mA active anodal tDCS (anode positioned at C3/4, cathode positioned at Fp1/2 as per 10-20 electrode placement guidelines) Behavioral: Physiotherapy motor skills based physiotherapy intervention (representative of typical goal-focused intervention in the clinical ABI program at Holland Bloorview), 45 minutes in duration
Study NCT05637957 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: sham transcranial direct current stimulation
Description: Device: 1 minute of 1.0 mA anodal tDCS (anode positioned at C3/4, cathode positioned at Fp1/2 as per 10-20 electrode placement guidelines) and 19 minutes with unit turned off and electrodes remaining in place Behavioral: Physiotherapy motor skills based physiotherapy intervention (representative of typical goal-focused intervention in the clinical ABI program at Holland Bloorview), 45 minutes in duration
Study NCT04804904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ-B3101
Description: TQ-B3101 oral capsule
Study NCT04826029 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard strategy
Description: In the standard arm, patients will complete CA 125 (+/- HE4) at 3 months, 6 months, 12 months, 18 months and 24 months (+/- 15 days), complete the HAD and EQ5D self-questionnaires, and be managed according to INCa 2018 recommendations. If clinical symptoms, marker elevation, and/or imaging workup occur, the patient will be referred to the multidisciplinary consultation meeting (MDC) for management according to INCa 2018.
Study NCT04826029 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Follow-up strategy
Description: In the interventional arm, patients will perform at 3 months, 6 months, 12 months, 18 months and 24 months (+/- 15 days) a CA125 assay (+/- HE4 assay), a thoracoabdominal CT scan after contrast injection and a whole body MRI (T2, DW and T1 sequences after fat saturation before and after gadolinium injection) with a maximum delay of 15 days between the two examinations, and will complete the HAD and EQ5D self-questionnaires. A senior radiologist from each center will perform a prospective reading of each of the images. For any suspicious anomaly identified, the following criteria will be analyzed: Size, location, number, evolution, contrast after injection, MRI signal (T2, Diffusion, Dynamic Enhancement Curve). The RECIST criteria (version 1.1) will be applied.
Study NCT05703113 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web 2.0 tools
Description: Education with Web 2.0 tools
Study NCT04781049 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Trans-Perineal Laser Ablation of Prostate
Description: TPLA treatment will be performed using the EchoLaser EVO system (Elesta SpA - Calenzano, FI, Italy). EchoLaser EVO consists of four echolasers, a multi-source laser system with a wavelength of 1064nm and Echolaser Smart Interface (ESI), a treatment planning device for safely inserting introductor needles and optical fibers into prostate tissue. EchoLaser therapy is a micro-invasive percutaneous procedure that uses laser light transmitted through applicators (optical fibers) for a few minutes, causing a heating of the affected tissue to its irreversible damage in situ, without the need to remove it. EchoLaser therapy, through flat-tip fibers, produces an ellipsoidal clotting area (area where the tissue has irreversible damage). EchoLaser therapy will be performed under ultrasound guidance.
Study NCT04781049 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Trans-Urethral Resection of Prostate
Description: TURP is the gold standard for the treatment of benign prostatic obstruction. It will be performed by using a bipolar energy resectoscope. The procedure will be carried out with patient in a lithotomic position.
Study NCT04791423 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GRAd-COV2
Description: GRAd-COV2 is a replication-defective gorilla adenoviral vector (GRAd) encoding the SARS-CoV-2 surface glycoprotein (S, Spike) antigen under the control of CMV immediate early promoter. The encoded Spike antigen is stabilized in pre-fusion conformation by introducing 2 proline residues
Study NCT04791423 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline solution
Study NCT04573764 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester
Description: The intervention is D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester and will be bought commercially. As an example: One bottle of KetoneAid KE4 PRO with 60 ml contains 30 g D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester. For more information please refer to: https://shop.ketoneaid.com/collections/all/products/ke4-pro. Placebo will be a taste-matched water solution provided by the company. The placebo solution and the active solution will be prepared in identic bottles and investigators will be blinded.
Study NCT04573764 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taste-matched water
Study NCT04719962 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Targeted proteomics in skin +/- cerebrospinal or synovial fluid to diagnose disseminated Lyme disease
Description: Following a 2-days course of local daily clobetasol propionate 0,05% cream application, a skin biopsy (3 mm punch-biopsy ) of healthy-looking skin of the upper part of the thigh will be performed in all patients,.~Arthrocentesis (in patients with Lyme arthritis only) and lumbar puncture to collect cerebrospinal fluid (in patients with neuroborreliosis only) will be performed in the usual care setting as appropriated.~All biological samples will be subject to Borrelia culture, PCR and SRM-MS proteomics.
Study NCT05515692 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Correlative studies
Study NCT05515692 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo radiotherapy simulation using CT
Study NCT05515692 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Electron Beam Therapy
Description: Undergo electron beam radiotherapy
Study NCT05515692 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High Frequency Ultrasound Imaging
Description: Undergo HFUS
Study NCT05515692 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05515692 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy Treatment Planning and Simulation
Description: Undergo radiotherapy simulation using clinical setup
Study NCT05515692 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Skin Biopsy
Description: Undergo biopsy
Study NCT06011213 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Issuing health risk warning for a heat waves or cold spells
Description: Whenever a health risk warning for a heat waves or cold spells is issued, only the elderly in the combined intervention group will be alerted to the early warning information through the digital heat or cold health risk early warning tool.
Study NCT06011213 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A digital heat or cold health risk early warning tool
Description: A WeChat mini-program provides real-time updates on early warnings and health advisories.
Study NCT06011213 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Self-monitoring blood pressure and ECG device
Description: Devices for self-monitoring blood pressure and ECG
Study NCT06011213 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Self-monitoring blood pressure and ECG device
Description: Devices for self-monitoring blood pressure and ECG
Study NCT06011213 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Perform daily self-monitoring of their BP and ECG
Description: Participants in the self-monitoring alone group were instructed to self-measure their BP three times each morning (from 6:00 a.m. to 8:00 a.m.) and evening (from 6:00 p.m. to 8:00 p.m.) at home, and to self-administer ECG measurements twice during the same morning and evening timeframes.
Study NCT06011213 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Perform daily self-monitoring of their BP and ECG
Description: Participants in the self-monitoring alone group were instructed to self-measure their BP three times each morning (from 6:00 a.m. to 8:00 a.m.) and evening (from 6:00 p.m. to 8:00 p.m.) at home, and to self-administer ECG measurements twice during the same morning and evening timeframes.
Study NCT04986423 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZEN003694
Description: 72 mg PO QD
Study NCT04986423 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Enzalutamide
Description: 160 mg PO QD
Study NCT04986423 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enzalutamide
Description: 160 mg PO QD
Study NCT06083285 — intervention group
Intervention type: OTHER
Intervention: Implement the CRRT specialist nursing group management program on the basis of routine care
Description: Training the department nurses on CRRT related theoretical knowledge and operation skills; guiding the process of CRRT different treatment modes, solving CRRT nursing problems, evidence-based nursing guidance; consulting CRRT treatment and nursing related treatment, timely understanding the new progress; responsible for CRRT nursing quality control, etc.
Study NCT06279091 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diaphragmatic Breathing
Description: apply breathing exercises to evaluate the effectiveness on anxiety reduction
Study NCT06279091 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bubble Blower Breathing
Description: apply breathing exercises by using bubble blower to evaluate the effectiveness on anxiety reduction
Study NCT06279091 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tell Show Do
Description: apply basic behavioral management technique as control group
Study NCT04394260 — intervention group
Intervention type: BEHAVIORAL
Intervention: Savvy Caregiver Program via Remote Learning
Description: The SCP program is comprised of four pre-recorded Savvy Caregiver videos (each 1 hour and 45 minutes in length). Course material was designed to provide informal caregivers with the knowledge, skills, and attitude needed to carry out their role as a caregiver for a person living with dementia (PLWD). Course learning objectives include: 1) introduction to dementing disorder; 2) caregiver self-care; 3) the anchors of enjoyable involvement; 4) levels of thinking and performance; 5) strengthening the family as a resource for caregiving; and 6) review and integration of the previous sections.