AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04181463 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04181463 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06478771 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lingual retainer
Description: A fixed retainer placed on the lingual side of the teeth.
Study NCT05919667 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dairy and plant-based dairy beverages and solids
Description: Crossover design: participants received all treatment arms in a randomized order
Study NCT05309135 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: HCEC-1
Description: HCEC-1 = human cultured corneal endothelial cells and Rho kinase Y-27632 inhibitor
Study NCT04823091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine + Cyclophosphamide + CAR7-T Cells
Description: fludarabine 30 mg/kg on day -5, -4, and -3; cyclophosphamide 250 mg/kg on day -5, -4, and -3; CAR7-T Cells on day 0.
Study NCT05921981 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multisensorial Stimulation
Description: Multisensory stimulation in newborns involves the deliberate and simultaneous activation of multiple sensory modalities to provide sensory experiences that promote development and enhance learning. Newborns are naturally inclined to explore and make sense of their environment through their senses, including touch, sight, sound, taste, and smell.
Study NCT05921981 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: White Noise
Description: White Noise
Study NCT06438640 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: My Anesthesia Choice-HF Model
Description: Brief clinician training on shared decision making, paired with provision of a 1-page tabular format conversation aid listing answers to frequently asked questions regarding common anesthesia options for hip fracture surgery (spinal anesthesia; general anesthesia)
Study NCT06273579 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental Group - Verbal expert instructor feedback in AI's words
Description: Expert instructor assigned to tutor this group will receive error detection data from the ICEMS. They will also be provided with a list of commands that the ICEMS uses. When the system detects an error in a student's performance for a given metric, the expert instructor must deliver this command in the same words as the ICEMS.
Study NCT06273579 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental Group - Verbal expert instructor feedback in expert's own words
Description: Expert instructor assigned to tutor this group will receive error detection data from the ICEMS. When the system detects an error in a student's performance for a given metric, the expert will deliver feedback in their own words.
Study NCT06331910 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: insulin eye drops
Description: Insulin eye drops deliver insulin directly to the cornea, They exploit insulin's ability to stimulate cell growth, potentially reducing healing time with minimal side effects.
Study NCT04403347 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Innovative Dietary Formulation (Patent ID: CN110250417A)
Description: In addition to regular diets and usual care of hypertension, additional innovative natural dietary formulation derived from tartary buckwheat will be orally taken 3 times per day.
Study NCT03064282 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: observation of skin changes if any
Study NCT03064282 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: papaverine
Description: observation of symptoms
Study NCT04403347 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Losartan 50mg per day
Description: In addition to regular diets and usual care of hypertension, antihypertensive medication will be orally taken (Losartan 50mg per day).
Study NCT05372744 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active Placebo labelled as antidepressant
Description: Participants receive an active nasal spray that is in fact a placebo with a specific framing in regards to its affect-regulatory characteristics, respectively.
Study NCT05569512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Uproleselan
Description: Administered by intravenous infusion
Study NCT05569512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Administered by intravenous infusion
Study NCT05569512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clofarabine
Description: Administered by intravenous infusion
Study NCT05569512 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Busulfan
Description: Administered by intravenous infusion
Study NCT06559878 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 13C-α-Ketoisocaproic Acid Breath Test
Description: 13C-α-Ketoisocaproic acid with L-Leucine soluted in citric acid drink. The solution is administered orally during metabolic visits (3.-5.).
Study NCT06559878 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ethanol
Description: 6% ethanol soluted in normal saline is given intravenously during one metabolic visit.
Study NCT06559878 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lipid Emulsion
Description: Lipid emulsion, heparin and normal saline are given intravenously during one metabolic visit.
Study NCT06559878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal Saline
Description: Normal saline is given intravenously during one metabolic visit.
Study NCT06049407 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Participation in a socio-emotional competence program through a technological platform (EMOWELL)
Description: (1) Participants who meet the inclusion criteria will be contacted. (2) Participants will answer the questionnaire battery (T1) (3) Participants will participate in the intervention by remotely playing the EMOWELL desktop serious game and the EMOWELL app. (4) They will answer the T2 questionnaires. (5) They will answer the follow-up (T3) questionnaires.
Study NCT05797519 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VDyne Transcatheter Tricuspid Valve Replacement System
Description: The study investigational device is the VDyne Transcatheter Tricuspid Valve Replacement System.
Study NCT05847478 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auricular acupressure of traditional Chinese Medicine
Description: The participants will be randomly assigned to receive the auricular point patch therapy.~The selected acupoints include Shenmen, hungry point, endocrine, stomach, mouth and subcortical. The opaque patch with vaccaria seed is used for acupoint pressing. Pressing the acupoints once a day before and after eating, each time for 1 minute, lasting for 2-3 days, follow up visit once a week. The intervention period is 3 months.
Study NCT05847478 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intermittent low carbohydrate diet
Description: The participants will be randomly assigned to the intermittent low carbohydrate diet group.~The intermittent carbohydrate diet includes 7 days of low carbohydrate diet within 2 weeks (consecutive or nonconsecutive, carbohydrate intake be controlled as ≤ 50g per day). The study duration is 3 months, including 1-month intervention period and 2-month self-maintenance period.
Study NCT05847478 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health education
Description: Health education is conducted once a week during 3-month intervention for all participants. Health education including the understanding of childhood obesity and cardiovascular disease, how to determine the cardiometabolic risk level, and the lifestyle intervention as caloric restriction and increased physical activity to promote health.
Study NCT06563037 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: This is an observational study
Study NCT06284941 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine combined with methylene blue for iliac fascia block
Description: Ultrasound guided iliac fascia block, administered with 30ml of 0.25% ropivacaine+0.05% methylene blue
Study NCT06498128 — intervention group
Intervention type: DRUG
Intervention: Daridorexant
Description: Dosing and treatment duration of QUVIVIQ as part of this observational study is at the discretion of the healthcare provider in accordance with local clinical practice and local labeling.
Study NCT06498128 — intervention group
Intervention type: DRUG
Intervention: Non-orexin receptor antagonist medications for insomnia
Description: Dosing and treatment duration of non-orexin receptor antagonist medications for insomnia as part of this observational study is at the discretion of the healthcare provider in accordance with local clinical practice and local labeling.
Study NCT06498128 — intervention group
Intervention type: OTHER
Intervention: No insomnia medication
Description: No insomnia medication was administered.
Study NCT05649072 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Genetic Testing and Counseling
Description: Participants will be asked to collect a saliva sample for hereditary cancer and genetic testing
Study NCT05649072 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Screening Form
Description: Participant will be answering demographic details
Study NCT06608966 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Epilepsy Journey web-based modules
Description: Participants assigned to Epilepsy Journey modules will independently review web-based EJ modules focused on executive functioning skills. The modules cover 10 topic areas: Positive Thoughts, Problem-Solving, Initiation, Working Memory, Monitoring, Inhibition, Emotional Control, Organization and Planning, Sleep/Stress, and a Wrap-Up. Participants will complete 10 modules (\~15-30 minutes each session) within a 14-week time frame. The goal is to complete one module per week.
Study NCT04849390 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ESO-101
Description: Daily administration in the evening at bedtime for 28 days
Study NCT04849390 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Daily administration in the evening at bedtime for 28 days
Study NCT06209749 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sensory-based intervention module
Description: Consists of sensory-based activities (Set A-F) with six weeks of individual sessions and six weeks of group sessions
Study NCT06443112 — intervention group
Intervention type: PROCEDURE
Intervention: transvaginal cervical cerclage by Mc Donald technique
Description: In the McDonald operation, a suture is is inserted around the exo-cervix as high as possible to approximate to the level of the internal os and thereby prevent second-trimester abortion.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry Needling
Description: Dry needling directly to the long head of the biceps tendon. The DN will be performed with disposable stainless-steel needles (.3 X 40mm; Seirin; Weymouth, MA) inserted into the skin over the most painful and/or thickened areas of the tendon, confirmed with palpation. Prior to insertion of the needle the overlying skin will be cleaned with alcohol. The needle will be inserted into the tendon. The technique will be a fast-in and fast-out technique described by Chiavaras et al.26 for 20-30 repetitions per session in up to 3 areas. An eccentric-concentric exercise program of the biceps muscle/tendon will follow each DN session and will be performed daily for the course of treatment and will be performed as described by McDevitt et al.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heavy Slow Load Exercise
Description: Eccentric exercise protocols have been found to be an effective treatment for tendinopathies of the upper and lower extremities and recent evidence supports heavy slow resistance training (including the addition of a concentric phase) as having better outcomes over eccentric exercise alone. Patients will use 1-5 pound weights to perform slow and controlled concentric and eccentric exercise to biceps muscle.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rotator cuff and scapular stabilization exercise program
Description: Both groups will be treated with a stretching and strengthening program. The rotator cuff and scapular stabilization strengthening and flexibility program used in this study has 3 phases and patients progress in phases based on their ability to perform a number of exercises using theraband or body weight resistance.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rotator cuff and scapular stabilization exercise program
Description: Both groups will be treated with a stretching and strengthening program. The rotator cuff and scapular stabilization strengthening and flexibility program used in this study has 3 phases and patients progress in phases based on their ability to perform a number of exercises using theraband or body weight resistance.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Soft tissue mobilization
Description: Both groups will receive soft tissue mobilization to the anterior shoulder.
Study NCT04073212 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Soft tissue mobilization
Description: Both groups will receive soft tissue mobilization to the anterior shoulder.
Study NCT05573685 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DiNaMo Study App
Description: Study App to be used in patients with 1 of the 4 indications of rheumatoid arthritis, fibromyalgia Irritable Bowel Syndrome, Diabetic Neuropathy
Study NCT06608966 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telehealth with a therapist
Description: Therapist will cover 10 areas of executive functioning during telehealth sessions, including Positive Thoughts, Problem-Solving, Initiation, Working Memory, Monitoring, Inhibition, Emotional Control, Organization and Planning, Sleep/Stress, and a Wrap-Up. Telehealth sessions with a therapist will occur via HIPAA-compliant videoconference (e.g. Microsoft Teams) each week ideally over the course of 14 weeks.
Study NCT06173349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PLZ4-coated paclitaxel loaded micelles (PPM)
Description: Given PLZ4-coated paclitaxel loaded micelles intravesically
Study NCT05298904 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Genetic Health Screen Panel
Description: This panel covers cardiomyopathy genes, and cancer genes. The results of this panel are reported as Positive (pathogenic or likely pathogenic mutation identified in one or more genes) or Negative (no pathogenic/likely pathogenic mutations identified).
Study NCT06679270 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metreleptin
Description: Metreleptin is a recombinant human leptin analog that is indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency
Study NCT06148935 — intervention group
Intervention type: DRUG
Intervention: Vericiguat (Verquvo, BAY1021189)
Description: Following the manner of observational study, no intervention will be provided in the study. Participants follow locally approved label, without interference by the study initiator or study protocol
Study NCT04428307 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conditional artemisinin combination therapy subsidy
Description: An additional discount on WHO-approved quality assured ACTs will be offered to individuals with a positive RDT.
Study NCT05632900 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Endoscopic ultrasound guided drainage of walled off pancreatic necrosis
Description: It is Therapeutic procedure to treat walled off pancreatic necrosis.
Study NCT05632900 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endoscopic ultrasound guided drainage of walled off pancreatic necrosis
Description: It is Therapeutic procedure to treat walled off pancreatic necrosis.
Study NCT04428307 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Testing incentive
Description: A small incentive will be paid to the provider each time they perform a malaria rapid diagnostic test.
Study NCT05084963 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IRL201104
Description: lyophilised powder for reconstitution for IV dosing
Study NCT05084963 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo for IRL201104
Study NCT05521360 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Autonomic Modulation Training
Description: AMT is a six week online behavioral intervention comprised of two components. The first component is an adapted (to online format) version of an established and publicly available HRVBF protocol (Lehrer et al, 2013, Biofeedback).The second is the integration of meta-cognitive coping skills and autonomic modulation breathing techniques into the HRVBF protocol (Arpaia \& Andersen, 2019 Frontiers in Psychiatry; Andersen, Arpaia \& Gustafsberg, 2021 Int J Emerg Ment Health and Human Resilience).
Study NCT05835804 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GCP intratumoral catheter
Description: After local anaesthesia, intratumoral catheter will be place (one or several depending tumour criteria).The catheter placement could be guided by radiological imaging. Gemcitabine (200mg/l), carboplatin (100mg/l) and paclitaxel (20mg/l) will be each diluted in each in 160ml of NaCl0.9%. GCP will be administered successively for 8hours, at 20ml/h with a total duration of 24hours. The ITC will be done every 28 days for 6 times maximum in case of good response and tolerance. Nivolumab 240 mg IV will be started 1 to 7 days before the first intratumoral infusion and every 15 days, until progression or 2 until years in case of partial response, complete response or stabilization. Evaluation of tumour size will be done by CT-scan, or MRI 2every 2 months and PET-FDG every 3 months.
Study NCT04532879 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HygiPrep (HyGIeaCare System)
Description: Controlled gravity-based high-volume colon irrigation
Study NCT05439707 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transaricular vagus nerve stimulation
Description: The transaricular vagus nerve stimulator was placed in the left ear trunk, which is dominated only by the auricular branch of the vagus nerve. Continuous stimulation was performed at a frequency of 25Hz with pulse width of 300 μs. The stimulation was adjusted to be higher than the perception threshold and lower than the pain threshold. Each stimulation lasted for 30 minutes, three times per day (morning, noon, evening), from 1 day before surgery to 7 days after surgery, and the treatment lasted for 9 consecutive days.
Study NCT05439707 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: fake transaricular vagus nerve stimulation
Description: The transaricular vagus nerve stimulator was placed in the same position as the experimental group, covered with an insulating film and placed at the site of the stimulation, so that the patient could not actually receive the electrical stimulation. Continuous stimulation was performed at a frequency of 25Hz and pulse width of 300 μs, and the stimulation was adjusted to be higher than the perception threshold and lower than the pain threshold. Each stimulation lasted for 30 minutes, three times per day (morning, noon, evening), from 1 day before surgery to 7 days after surgery, for 9 consecutive days.
Study NCT06268145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ECC5004
Description: A single dose tablet of 50 mg of the current tablet formulation (F1) or new tablet formulation (F2) administered orally.
Study NCT05171829 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Track U
Description: Track U diary
Study NCT05578027 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mild moxibustion with moxa stick
Description: To conduct this intervention, we used moxa sticks which were 1.5 cm in diameter, 13 cm long, and weighed 12 gram to perform mild moxibustion manipulation at the control acupoint (the left side Pishu acupoint) or Mingmen acupoint in 2 trial phases. The main ingredient of the moxa was dried mugwort leaf, produced in Vietnam. All moxa materials were obtained from the Sai Gon TCS Co., Ho Chi Minh City, Vietnam.
Study NCT06179368 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: hypothroidism
Description: throid fuction will be evaluated on admission of hepatic failure patients, and the hypothyroid patients will be enroled in this group.
Study NCT06179368 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: euothyroid
Description: throid fuction will be evaluated on admission of hepatic failure patients, and the euothyroid patients will be enroled in this group.
Study NCT05018936 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hetrombopag
Description: Hetrombopag starting at 5mg/day and increased by 2.5mg/day every 2 weeks if the platelet count remains less than 20×10e9/L and reduced if the platelet count reaches over than 150×10e9/L.
Study NCT06119022 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Invasive coronary angiography
Description: Patients with positive myocardial ischemia either in CT-MPI guided arm or SPECT-MPI guided arm will scheduled to undergo invasive coronary angiography.
Study NCT06119022 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Invasive coronary angiography
Description: Patients with positive myocardial ischemia either in CT-MPI guided arm or SPECT-MPI guided arm will scheduled to undergo invasive coronary angiography.
Study NCT06119022 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: routine medical treatment
Description: Patients with negative myocardial ischemia either in CT-MPI guided arm or SPECT-MPI guided arm will scheduled to have routine medical therapy instead of invasive coronary angiography.