AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05351827 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mild Intermittent Hypoxia
Description: Participants will breathe 8% oxygen through a non-diffusable bag that is connected to a 5-way stopcock. The inspiration side of the system is then connected to a 2-way non-rebreathing valve which is connected to a pneumotachometer that is connected to a tight fitting facemask. 100% oxygen and carbon dioxide are titrated into the system to ensure the appropriate hypoxic and hypercapnic stimulus is delivered. The investigators will lower oxygen to 55-60 mmHg and maintain end-tidal carbon dioxide 1-3 mmHg above individual baseline values. The protocol starts with 10 minutes of baseline breathing (room air) then followed by 10 more minutes of breathing room air with the additional carbon dioxide. Thereafter, individuals undergo 12 2-minute bouts of hypoxia with 2 minutes of normoxia (room air) interspersed between episodes. The intervention protocol concludes with 20 minutes of monitoring all breathing and cardiovascular measurements.
Study NCT05351827 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: Participants will breathe 21% oxygen through a non-diffusable bag that is connected to a 5-way stopcock. The inspiration side of the system is then connected to a 2-way non-rebreathing valve which is connected to a pneumotachometer that is connected to a tight fitting facemask. No supplemental oxygen or carbon dioxide will be used during the sham protocol. The protocol starts with 10 minutes of baseline breathing (room air) then followed by 10 more minutes of breathing room air with the additional carbon dioxide. Thereafter, individuals undergo 12 2-minute bouts of hypoxia with 2 minutes of normoxia (room air) interspersed between episodes. The intervention protocol concludes with 20 minutes of monitoring all breathing and cardiovascular measurements.
Study NCT06617182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thalidomide
Description: Patients in thalidomide group took thalidomide orally at a dose of 100mg once a day for 8 weeks.
Study NCT06617182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glutamine
Description: In the glutamine group, two capsules of glutamine were taken orally 3 times a day for 8 weeks.
Study NCT06617182 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thalidomide+Glutamine
Description: Patients in thalidomide combined with glutamine group took thalidomide orally at a dose of 100mg once a day and two capsules of glutamine were taken orally 3 times a day for 8 weeks.
Study NCT06620705 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Left bundle branch area pacing
Description: Pacing of the left bundle branch area using a transvenous pacemaker lead
Study NCT06620705 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Biventricular pacing
Description: Pacing of the right and left ventricle using transvenous pacemaker leads
Study NCT06618235 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: THEO-260
Description: Oncolytic Virus
Study NCT06621212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mitoxantrone hydrochloride liposome
Description: Mitoxantrone hydrochloride liposome (30 mg/m\^2) on day 1, every 4 weeks
Study NCT06621212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Cytarabine (100 mg/m\^2 ) on day 1-7, every 4 weeks
Study NCT06621212 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax 100 mg on day 2，200 mg on day 3，400 mg on day 4-10, every 4 weeks
Study NCT06619158 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Crown modification
Description: Zirconia glaze removal and polish after crown removal to reduce roughness and prohibit plaque adhesion
Study NCT06620770 — intervention group
Intervention type: OTHER
Intervention: questionnaires
Description: Morisky and SF12 Questionnaires delivery at inclusion, 6, 12 and 18 months
Study NCT06620354 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selumetinib
Description: Patients without indications for surgical excision were evaluated with 6 cycles of daily oral smetinib capsules (20-50mg bid) for 30 days, individually calculated based on patient body surface area (BSA)
Study NCT06620796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arm 1
Description: Ivonescimab combined with Cadonilimab plus EC
Study NCT06620796 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: second-line group
Description: AK112+AK104+paclitaxel
Study NCT06621706 — intervention group
Intervention type: DEVICE
Intervention: Gastric ultrasonography
Description: Women will be requested to fast 2 hours for clear drinks, 6 hours for a light meal, and 8 hours for a meal high in fried or fatty content prior to their next antenatal clinic visit.~On the day of assessment, fasting and dietary compliance will be confirmed individually with each woman and Gastric ultrasonography will be performed after sex and eight hours of fasting food.~Women will be first scanned in a semi-recumbent (45 degrees head up) supine position, followed by a semi-recumbent (45 degrees head up) right lateral position (RLP). In both positions the gastric antrum will be identified in the sagittal plane with its internal anatomical landmarks identified, i.e. the left lobe of the liver anteriorly and the abdominal aorta posteriorly.
Study NCT06618482 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: Low back kinesiotaping
Study NCT06618482 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: Transversus abdominis kinesiotaping
Study NCT06424990 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: balance training with TENS
Description: children will receive Biodex balance training with TENS for 30 minutes a day, 5 days per week for 4 weeks
Study NCT06424990 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Balance training with placebo TENS
Description: children will receive Biodex balance training with placebo TENS for the same period.
Study NCT06620965 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mulligan Mobilization Technique
Description: NAGs (Natural Apophyseal Glides) involve passive oscillatory movements of a spinal facet joint in an anterocranial direction, performed with the patient seated. SNAGs (Sustained Natural Apophyseal Glides) maintain facet glides during active movements, aiming to reach the joint\&#39;s end range. In SNAGs, the patient actively participates, and overpressure is applied at the end of movements to enhance the range of motion. Techniques include increasing rotation, lateral flexion, flexion, and extension. These were applied by a certified physiotherapist three times a week for four weeks, aiming to improve joint mobility without causing pain.
Study NCT06620965 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Proprioceptive Neuromuscular Facilitation (PNF) Technique
Description: Proprioceptive Neuromuscular Facilitation (PNF) Technique: PNF consists of four movement patterns in two diagonals:~Flexion-left rotation and extension-right rotation Flexion-right rotation and extension-left rotation 3 PNF techniques were applied.~Combined Isotonic Contractions: This technique involves concentric, eccentric, and stabilizing contractions of a muscle group (agonist). The goal is to increase active range of motion (ROM), strength, and improve control and coordination.~Dynamic Stabilization (Stabilizing Reversal): This involves applying resistance in various directions to prevent movement, aiming to enhance dynamic stability, strength, and agonist-antagonist coordination.~Hold-Relax Technique: This relaxation method involves isometric contractions against maximum resistance without movement to increase passive ROM and reduce pain. These were applied by physiotherapist three times a week for four weeks, aiming to improve joint mobility without causing pain.
Study NCT06624215 — intervention group
Intervention type: PROCEDURE
Intervention: Appendectomy
Description: Robotic-assisted or laparoscopic appendectomy for acute appendicitis.
Study NCT05150587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rifaximin
Description: Rifaximin tablets
Study NCT05150587 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo tablets
Study NCT04736550 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants who are randomized to exercise will be perform exercise on stationary bikes. Participants randomized to Voluntary Exercise will exercise on a standard stationary bike where they will pedal at their voluntary rates. Participants randomized to Assisted Exercise will exercise on a special bike that assists them to pedal faster than they do voluntarily on their own (assisted (exercise) bike).
Study NCT04736550 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy for Pain (I-STOP)
Description: Participants who are randomized to receive I-STOP will receive the Self-regulation Treatment for Opioid addiction and Pain (STOP) program modified for inpatients/residential drug treatment (I-STOP). I-STOP uses empirically validated pain psychotherapy approaches targeted to patients with an OUD using psycho-physiological self-regulation components and biofeedback with Bio-dots.
Study NCT05351138 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TENS
Description: In the study, CE certified tens device with Biolito brand, which is used specifically for incontinence treatment, will be used. The electrodes used during the intervention will be placed to the parasacral region (S2-S4). While the current is given, the power of the device will be gradually increased in 1 mA intervals. The lower value of the stimulation will be 10 mA and the upper value will be 25 mA, and the treatment will be continued with any value that the child can tolerate in this range.
Study NCT05351138 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: The massage will be applied to the abdominal area between the subcostal lower border and the anterior superior of the spina iliaca. Massage techniques are as follows: Abdominal patting, colon patting, colon kneading, colon patting again, abdominal patting again. It will be advanced with deep abdominal strokes, then the starting point will be returned with transverse superficial strokes for the transversus abdominis muscle and oblique superficial strokes for the rectus abdominis muscle, and these strokes will be repeated 3 times each, a total of 6 times. Afterwards, 3 times column brushing, 3 times column kneading and 3 times column plastering will be done, respectively. At the end, a total of 6 abdominal strokes will be performed for both the transversus abdominis and oblique abdominal muscles as in the beginning.
Study NCT06434597 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPH5030
Description: SPH5030：Oral, QD, 600mg
Study NCT05247827 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Targeted phantom limb motor execution (exercise)
Description: The targeted phantom motor execution is a specific training program for people with TTA that has been designed to improve the muscles' strength, coordination, and flexibility at the amputated and contralateral intact sides. Such training consists of repeated short-term, short rest interval, and moderate-intensity exercises (Schoenfeld 2010, Krutki, Mrowczynski et al. 2017). Targeted phantom motor execution can improve the body image considering its induced muscular impacts. People with TTA will be trained to follow specific movements of their foot-ankle complexes simultaneously, in order to increase PLA, as well as induce muscular morphologic and brain neuroplastic changes (Moseley and Brugger 2009).
Study NCT05539521 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam Besylate
Description: sedation drugs
Study NCT05539521 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Propofol
Study NCT05100719 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: alverine-citrate + simethicone and lactase
Description: Patients who randomized in the first arm are treated with alverine-citrate + simethicone and lactase.
Study NCT05100719 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: alverin-citrate + simethicone with placebo
Description: Patients in the second arm receive alverin-citrate + simethicone with placebo without lactase.
Study NCT06316219 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nomegestrol Acetate/Estradiol 2.5mg/1.5mg
Description: hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol 2.5mg/1.5mg at any time of the menstrual cycle
Study NCT05374759 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: neutrophil gelatinase-associated lipocalin
Description: When the patient is diagnosed with sepsis and on the 3rd day of the follow-up, blood samples will be taken and NGAL levels will measured.
Study NCT05374759 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: renal resistive index
Description: When the patient is diagnosed with sepsis and on the 3rd day of the follow-up, renal resistive index will measure and record.
Study NCT04699227 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cuff application with inflation
Description: The blood pressure cuff will be placed on the arm and inflated.
Study NCT04699227 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham inflation
Description: The blood pressure cuff will be placed on the arm and not inflated.
Study NCT04987190 — intervention group
Intervention type: PROCEDURE
Intervention: alveolar bone graft
Description: alveolar bone graft with Scarpa fascia done when patients were at 9 year of age
Study NCT06205641 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Xuanfei Baidu Granule Placebo
Description: Take Xuanfei Baidu Granule Placebo 1 bag in the morning and evening with boiling water for 5 days.
Study NCT06205641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Xuanfei Baidu Granule
Description: Take Xuanfei Baidu Granule 1 bag in the morning and evening with boiling water for 5 days.
Study NCT06619548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auricular magnet with a magnetic strength of 1800 Gauss
Description: Auricular magnets with a magnetic strength of 1800 Gauss are used as the experimental group.
Study NCT06619548 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Auricular magnet with a magnetic strength of 1800 Gauss
Description: Auricular magnets with a magnetic strength of 1800 Gauss are used as the experimental group.
Study NCT06619548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auricular magnet with no magnetic strength
Description: Auricular magnets with no magnetic strength are used as placebo control.
Study NCT06619548 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Auricular magnet with no magnetic strength
Description: Auricular magnets with no magnetic strength are used as placebo control.
Study NCT04857814 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ADAMM- RSM Device
Description: All participants will wear the ADAMM- RSM device for a 6 month period
Study NCT06375616 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nafamostat Mesylate
Description: During RRT, a priming dose of 20 mg of nafamostat mesylate (NM) is administered before initiation of the procedure. Upon starting the machine, there is no loading dose, but a maintenance infusion rate of 25 mg/h of NM is maintained. NM is discontinued in the last half hour before the end of the RRT session.
Study NCT06375616 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Unfractionated Heparin
Description: During RRT, a priming dose of 50 mg of unfractionated heparin (UFH) is administered before initiation of the procedure. Upon starting the machine, a loading dose of 0.2 mg/kg of UFH is given, followed by a maintenance infusion rate of 0.1 mg/kg/h of UFH. The anticoagulant is discontinued in the last half hour before the end of the RRT session.
Study NCT05026099 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Boxing training
Description: Boxing training: warm-up. Mitt hitting, sandbag hitting, in sitting, cool down, Assessment after 4 weeks boxing training: warm-up. Mitt hitting, sandbag hitting, below hips, cool down, Assessment after 6 weeks Boxing training: warm-up. Mitt hitting, sandbag hitting, both inn sitting and standing, cool down, Post assessment
Study NCT05026099 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Task Oriented Training
Description: Task-oriented training: 6 tasks in sitting and standing position for both upper and lower limb Assessment after 4 weeks Task oriented training: 6 tasks in sitting and standing position for both upper and lower limb Assessment after 6 weeks Task oriented training: 6 tasks in sitting and standing position for both upper and lower limb Post assessment
Study NCT05341336 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: total surgical excision
Description: patients will be operated under general anesthesia. Pressure is applied along the incision line while staying away from the palpable margin of the AVM lesion and used Raney clips to control bleeding.~Once the skin flap was raised, the lesion could be seen through the galea. The galea around the lesion is incised, and the lesion will be separated from the underlying skin using a combination of bipolar diathermy and sharp dissection.~The nidus is often located in galeal aponeurosis. Dilated arteries and veins extended into subcutaneous tissue, which was separated with special care to prevent accidental nidus rupture and avoid excessive cauterization to prevent postoperative scalp necrosis.~Ligation is applied on feeder arteries, then applied to veins with total excision of the lesion.~After excision of the lesion, the skin flap was replaced with interrupted stitches.~The wound was allowed to heal primarily along with intravenous administration of antibiotics.
Study NCT05948566 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TS23
Description: Monoclonal antibody
Study NCT05948566 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: TS23
Description: Monoclonal antibody
Study NCT05243342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XmAb24306
Description: XmAb24306 will be given via intravenous (IV) infusion
Study NCT05243342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Participants will receive daratumumab via subcutaneous (SC) injection every week for Cycles 1-4, every 2 weeks for Cycles 5-12, and every 4 weeks thereafter (cycle length = 2 weeks for Cycles 1-12 and 4 weeks thereafter)
Study NCT05113641 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Alkalizing Fruit and Vegetables
Description: The weekly deliveries will contain combinations of fresh, frozen, and dried fruits and vegetables, as well as juices and soups which have been selected for their negative potential renal acid load (PRAL) values and shelf-life. All participants will be started at a F+V intake equal to -30 to -40 mEq per day reduction in dietary acid load estimated by the PRAL equation. Participants serum bicarbonate concentration will be measured at 1 month, and at 3 months, those with values \< 22 mEq/L will have their recommended amount of F+V increased to -40 to -50 mEq per day. If a participant's 1- or 3-month serum bicarbonate value exceeds 29 mEq/L, their target dose of F+V in mEq/d will be reduced by 25%.
Study NCT05113641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium bicarbonate
Description: Study nephrologist will prescribe the oral alkali therapy (sodium bicarbonate) and the medications will be dispensed by the Seven Oaks Hospital pharmacy.
Study NCT05659979 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Comprehensive geriatric assessment
Description: A detailed comprehensive geriatric assessment will be given to all the participants randomized to this group, including the administration of multidimensional prognostic index (MPI), a tool derived from the CGA and consisting of eight different domains.
Study NCT06391541 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: modified thoracolumbar interfacial plan block (mTLIP)
Description: Injecting local anesthetic at L3 vertebral level between the longisimus and iliocostalis muscles within the erector spinae muscles.
Study NCT06391541 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intertransverse process block (ITP)
Description: injection of local anesthetic on the superior costotransverse ligament between the transverse process and the pleura.
Study NCT05738551 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stress ball
Description: Applicable to group 1
Study NCT05738551 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: chewing gum
Description: Applicable to group 2
Study NCT05797415 — intervention group
Intervention type: PROCEDURE
Intervention: Sentinel Lymph Node Biopsy
Description: * Injection of 99mTc-labeled nanocolloids~* Preoperative lymphoscintigraphy~* Intraoperative gamma probe search of the sentinel lymph node~* Sentinel lymph node biopsy~* Excisional biopsy of the neoformation in cases not undergoing excision before SLN biopsy.~* If the SLN is histologically positive, the multidisciplinary team will consider whether to refer the patient for parotidectomy and excision of the lymph node chain and/or adjuvant radio/chemotherapy.
Study NCT06027697 — intervention group
Intervention type: DEVICE
Intervention: AccuFill® Porous Bone Substitute Material (BSM)
Description: The patient will undergo a minimally invasive surgery procedure (subchondroplasty) to receive the medical device AccuFill® Porous Bone Substitute Material (BSM).
Study NCT06278753 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: carbon dioxide cystoscopy
Description: Using carbon dioxide medium for filling bladder
Study NCT06466876 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: retrieval-based word learning
Description: Word learning intervention that compares two strategies for teaching novel words