AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05002777 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rilzabrutinib
Description: Pharmaceutical form: Tablet Route of administration: Oral
Study NCT04815434 — intervention group
Intervention type: OTHER
Intervention: Interview
Description: Interviews will be conducted.
Study NCT05413733 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital care pathway
Description: Sessions of the digital neuropsychological program:~1. Subjective functional ability and goals~2. Fatigue after ABI~3. Attention and concentration~4. Memory~5. Memory strategies~6. Working memory and executive functions~7. Emotional reactions~8. Summary and future goals
Study NCT05413733 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Care as usual
Description: The standard care of patients with ABI including all necessary outpatient rehabilitation visits. Neuropsychological visits may include a short period of psychoeducation with a clinical neuropsychologist.
Study NCT06083987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intersectionality and Identity
Description: Participants will use the computer application, Discord, a social media site that allows for sharing of content and interaction with other people in a variety of forms (video chat, direct messaging, and talking in group chat areas). We will be using the group chat function to set up discussion forums where there will be video and text resources focused on matters of intersectionality and identity. Participants will do at least one activity from three types each week for four weeks. The three activity types will have the participants engage with the content and then either discuss it in the forum (Talk about it), write a review about the content discussing why/why not they like it (Rate it), or Attempt to use the knowledge or skills to accomplish a task offline (Try it).
Study NCT06083987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Confidentiality
Description: Participants will use the computer application, Discord, a social media site that allows for sharing of content and interaction with other people in a variety of forms (video chat, direct messaging, and talking in group chat areas). We will be using the group chat function to set up discussion forums where there will be video and text resources focused on Confidentiality for caregivers. Participants will do at least one activity from three types each week for four weeks. The three activity types will have the participants engage with the content and then either discuss it in the forum (Talk about it), write a review about the content discussing why/why not they like it (Rate it), or Attempt to use the knowledge or skills to accomplish a task offline (Try it).
Study NCT06083987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educating Your Community
Description: Participants will use the computer application, Discord, a social media site that allows for sharing of content and interaction with other people in a variety of forms (video chat, direct messaging, and talking in group chat areas). We will be using the group chat function to set up discussion forums where there will be video and text resources focused on matters of the education of family and friends about identity. Participants will do at least one activity from three types each week for four weeks. The three activity types will have the participants engage with the content and then either discuss it in the forum (Talk about it), write a review about the content discussing why/why not they like it (Rate it), or Attempt to use the knowledge or skills to accomplish a task offline (Try it).
Study NCT06083987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: How to find Affirming Caregivers
Description: Participants will use the computer application, Discord, a social media site that allows for sharing of content and interaction with other people in a variety of forms (video chat, direct messaging, and talking in group chat areas). We will be using the group chat function to set up discussion forums where there will be video and text resources focused on matters of finding affirming caregivers. Participants will do at least one activity from three types each week for four weeks. The three activity types will have the participants engage with the content and then either discuss it in the forum (Talk about it), write a review about the content discussing why/why not they like it (Rate it), or Attempt to use the knowledge or skills to accomplish a task offline (Try it).
Study NCT06083987 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Group - No Interventions
Description: Control Group - Will be given no interventions
Study NCT05452434 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mirabegron
Description: mirabegron 50mg QD for 12 weeks.
Study NCT05452434 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mirabegron
Description: mirabegron 50mg QD for 12 weeks.
Study NCT06539676 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nighttime Aligners
Description: Nighttime aligners worn 10-12 hours per day or night during 2-8 months
Study NCT04932460 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CEUS
Description: CEUS is performed before neoadjuvant treatment and surgery to evaluate the status of axillary lymph node and locate the sentinel lymph node.
Study NCT04932460 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: blue dye
Description: Before operation, blue dye is injected for sentinel lymph node mapping.
Study NCT05095038 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Appethyl®
Description: Spinach extract, capsules, 5g/day, 26 weeks.
Study NCT05095038 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pea protein, capsules, 5g/day, 26 weeks.
Study NCT05985395 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HEART Camp Connect
Description: Once eligible and enrolled, participants will complete 150 minutes of moderate-intensity exercise a week with help of a virtual exercise coach.
Study NCT05100901 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MAG oil oral nutritional supplement (ONS)
Description: The study product is suitable for use as an oral nutritional supplement (ONS).The study product contains MAG oil, hydrolyzed whey protein, simple carbohydrates, vitamins and minerals.
Study NCT05309486 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Online and Face-to-face Pilates trainings
Description: Key elements of Pilates, including breathing, focusing, rib cage position, shoulder position, and head and neck positions, will be taught in both groups on the first day. Individuals will be asked to maintain the smoothness of these critical elements throughout the exercises. Different imagery techniques will be used in the exercises, and the exercises will be combined with breathing exercises. The intensity of the exercises will be increased by using different positions and elastic bands (Theraband Elastic Band Hygienic Corporation, Akron, Ohio). Band Resistances will be increased in biweekly periods. Stretching and posture exercises will be used during the cool-down period. The subjects in pilates group will be informed about the side effects such as shortness of breath, dizziness, headache, and muscle pain. Participants will be asked to stop the exercise in case of any side effects.
Study NCT06539676 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Daytime Aligners
Description: Daytime aligners worn 20-22 hours per day or night during 2-8 months
Study NCT06373081 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-CD19-CD3E-CAR-T cells
Description: The injection of anti-CD19-CD3E chimeric antigen receptor T (CAR-T) cells, referred to as anti-CD19-CD3E-CAR-T cells. The anti-CD19-CD3E-CAR protein is composed of a murine-derived CD19 single-chain variable fragment (scFv) FMC63, CD28 hinge and transmembrane regions, the intracellular domain of CD3E, the intracellular domain of CD28, and the intracellular domain of CD3ζ, all linked in sequence.
Study NCT06157580 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Compound 21
Description: differences in vasodilation to compound 21 in the skin between groups
Study NCT06157580 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Angiotensin II
Description: differences in vasoconstriction to angiotensin II in the skin between groups
Study NCT04929262 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supporting Anxious Youth: Strategies for Caregivers
Description: The outreach presentation will last 75 minutes with an additional 15 minutes for caregiver questions. The presentations will occur in the evening via Zoom. The presentation will include information about identifying anxiety disorders, strategies for caregivers to help their youth with anxiety, evidence-based practices to treat youth anxiety, and strategies for finding a therapist who uses cognitive behavior therapy with exposures. The text on the presentations is written at a 5.3 grade reading level. Presentations will incorporate stigma reduction strategies, such as education to dispel myths, and behavioral decision-making tools to elicit hope, empowerment, and motivation.
Study NCT04929262 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supporting Anxious Youth: Strategies for Caregivers
Description: The outreach presentation will last 75 minutes with an additional 15 minutes for caregiver questions. The presentations will occur in the evening via Zoom. The presentation will include information about identifying anxiety disorders, strategies for caregivers to help their youth with anxiety, evidence-based practices to treat youth anxiety, and strategies for finding a therapist who uses cognitive behavior therapy with exposures. The text on the presentations is written at a 5.3 grade reading level. Presentations will incorporate stigma reduction strategies, such as education to dispel myths, and behavioral decision-making tools to elicit hope, empowerment, and motivation.
Study NCT05961592 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: R-2487
Description: Probiotic
Study NCT06027242 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: oral glutamine
Description: 10 g glutamine +5 g Maltodextrin for 28 days after surgery with tolerable oral intake or enteral feeding
Study NCT06027242 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Maltodextrin
Description: Maltodextrin
Study NCT06027242 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Maltodextrin
Study NCT05309486 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online and Face-to-face Pilates trainings
Description: Key elements of Pilates, including breathing, focusing, rib cage position, shoulder position, and head and neck positions, will be taught in both groups on the first day. Individuals will be asked to maintain the smoothness of these critical elements throughout the exercises. Different imagery techniques will be used in the exercises, and the exercises will be combined with breathing exercises. The intensity of the exercises will be increased by using different positions and elastic bands (Theraband Elastic Band Hygienic Corporation, Akron, Ohio). Band Resistances will be increased in biweekly periods. Stretching and posture exercises will be used during the cool-down period. The subjects in pilates group will be informed about the side effects such as shortness of breath, dizziness, headache, and muscle pain. Participants will be asked to stop the exercise in case of any side effects.
Study NCT04635111 — intervention group
Intervention type: DRUG
Intervention: TURALIO™
Description: This is a non-interventional, observational study to evaluate long-term risk of hepatic failure associated with TURALIO™ (pexidartinib) treatment. No study medication will be provided to the participants.
Study NCT06094062 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App-based treatment support
Description: The intervention includes a smartphone app that patients will download on their smartphones. Medication intake, symptom course and well-being will be tracked over treatment duration. If symptoms worsen, the pharmacist will contact the patients and counsel them based on their adherence and well-being data. Patients who still have symptoms after the 30 days of treatment will receive a final counseling by the pharmacy, and if necessary will be forwarded to the treating physician.
Study NCT05304390 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Navigation
Description: Receive patient navigation intervention
Study NCT05304390 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT05304390 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smoking Cessation Intervention
Description: Receive an intervention for smoking cessation
Study NCT05304390 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Carbon Monoxide Measurement
Description: Undergo carbon monoxide measurement
Study NCT05824338 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia for lumbar surgery: ropivacaine
Description: The anesthesiologist will administer 4 mL of ropivacaine 0.5% plus fentanyl 15 mcg intrathecally
Study NCT05824338 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Spinal anesthesia for lumbar surgery: bupivacaine
Description: The anesthesiologist will administer 3 mL of bupivacaine 0.5% plus fentanyl 15 mcg intrathecally.
Study NCT05824338 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: General anesthesia for lumbar surgery
Description: Patient will be intubated and ventilated under general anesthesia.
Study NCT06337110 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lu AF28996
Description: Oral solution containing radiolabelled \[14C\]-Lu AF28996.
Study NCT05306600 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: whole exome and whole genome sequencing analysis
Description: Somatic and germline whole exome sequencing will be analyzed for prostate and HER2-positive breast cancer~Somatic whole exome and germline whole genome sequencing will be analyzed for triple-negative breast cancer
Study NCT06209359 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ammonium Chloride
Description: Participants will be randomized to receive either ammonium chloride or placebo. Participants will receive randomized drug in combination with IV bumetanide, bendroflumethiazide, and amiloride. Following a washout period, participants will be crossed over to the alternate drug.
Study NCT06209359 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be randomized to receive either ammonium chloride or placebo. Participants will receive randomized drug in combination with IV bumetanide, bendroflumethiazide, and amiloride. Following a washout period, participants will be crossed over to the alternate drug.
Study NCT05487586 — intervention group
Intervention type: DRUG
Intervention: ceftazidime avibactam group
Description: Non-Interventional Study
Study NCT05284058 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cardiac Magnetic Resonance Imaging (MRI)
Description: Patients will undergo 2 MRI exams: 1 MRI before surgical intervention (maximum 21 days before) and 1 MRI three months after surgery (+/- 14 days), with intravenous administration of gadolinium.
Study NCT05823987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: H101
Description: a modified human recombinant type 5 adenovirus with genetic modifications
Study NCT05823987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: a PD-1 immune check inhibitor
Study NCT05823987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenvatinib
Description: Lenvatinib capsules
Study NCT05608967 — intervention group
Intervention type: DEVICE
Intervention: PREHapp
Description: Prehabilitation programme through the PREHapp platform
Study NCT05800821 — intervention group
Intervention type: PROCEDURE
Intervention: Carotid revascularization
Description: Carotid revascularization
Study NCT05290740 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine 5 mcg
Description: norepinephrine bolus of 5 mcg for treatment of sever postspinal hypotension
Study NCT05290740 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine 10 mcg
Description: norepinephrine bolus of 10 mcg for treatment of sever postspinal hypotension
Study NCT06569082 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CD34+ Selected Donor Cell Boost
Description: The CliniMACS CD34 Reagent System is used to separate CD34 cells from the remaining stem cell product, using a peripheral blood stem cell sample provided by the original donor. These CD34 cells are then infused into the recipient following selection with the intent to restore function of the blood forming cells.
Study NCT06569082 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blood Stem Cell Infusion
Description: The selected CD34 cells separated by the CliniMACS CD34 Reagent System are infused into the recipient.
Study NCT05933577 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: V940
Description: IM injection
Study NCT05933577 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pembrolizumab
Description: IV infusion
Study NCT05933577 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion
Study NCT05933577 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: IM injection
Study NCT05672576 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cenerimod
Description: Cenerimod will be supplied as film-coated tablets at the dose of 4 mg.
Study NCT05672576 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo will be supplied as identical film-coated tablets formulated with the same excipients but without the active ingredient, cenerimod.
Study NCT06392100 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Intervention
Description: Mindfulness-based stress reduction interventions include: breathing awareness, loving-kindness meditation, body scan, walking meditation, sitting body awareness, eating meditation, and deep breathing exercises.
Study NCT06309719 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA)
Description: A conservative access flap will be performed such as simplified papilla preservation flap (SPPF). A PNHA gel will be placed on the root surfaces and supra-bony defects, followed by a tension-free primary closure of the interdental papillae and of the mucoperiosteal flaps by means of 5-0 suture
Study NCT06309719 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Periodontal Access Flap (AF)
Description: A conservative access flap will be performed such as simplified papilla preservation flap (SPPF). No gel will be placed before suturing the flap by tension-free primary closure of the interdental papillae and of the mucoperiosteal flaps by means of 5-0 suture
Study NCT05094596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standart treatment group
Description: Group 1 (n=60) received standard treatment in accordance with our national COVID-19 diagnosis and treatment guide.
Study NCT05094596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Montelukast sodium 10 mg treatment
Description: Group 2 (n=60) received 10 mg/day oral montelukast in addition to standard treatment
Study NCT05094596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Montelukast sodium 20 mg treatment
Description: Group 3 (n=60) were given 20 mg/day oral montelukast in addition to standard treatment.
Study NCT05974943 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Problem Solving And Decision Making Education
Description: The Problem-Solving and Decision-Making Training Program, which was based on developing problem-solving and decision-making skills of nurse managers in the experimental group (n=30), was prepared. 2 faculty members and the researcher organized the training program consisting of four modules and 16 hours.~In the content of the Training Program; the definition of the concept of problem-solving and decision-making, the process of problem-solving and decision-making and decision-making models, the impact of decision-making on employee, patient and organizational outcomes, and the importance of managers' roles in decision-making, the importance of the role of nurse managers in decision making, the impact of managerial decisions on patient care outcomes, the impact of managerial decisions on nurse outcomes, the impact of administrative decisions on organizational results/performance, problem-solving, and decision-making techniques and case studies.
Study NCT05478122 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Trachospray for awake videolaryngoscopy
Description: Subjects will be asked to inhale 4 ml lidocaine 4% via the Trachospray device
Study NCT06107920 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant chemotherapy
Description: Diverting stoma- neoadjuvant chemotherapy - colectomy - +/- adjuvant chemotherapy
Study NCT05552547 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Home Blood Pressure Machine
Description: Participants will be asked to measure blood pressure twice daily for three days in a row at home.
Study NCT05552547 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 24-Hour Blood Pressure Machine
Description: Participants will be asked to wear the machine for 24 hours.