AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05461456 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fexofenadine Hydrochloride Topical Lotion 1% (OP2101)
Description: Intervention:~The amount of study lotion (OP2101) used is 11 grams per subject, equivalent to 22 fingertip units (FTU). The lotion is applied to the subject on back and front of the trunk, both hands (palm and back) and both arms. An SOP for handling and application of the lotion ensures the 11 grams covers 54% of the body surface area (BSA) evenly without residue.~Comment:~The treatment is single-dose and single-treatment. The FTU is used to standardize the amount of cream being applied in clinical research. It is also used in clinical practice and hence connects the objectiveness of the trial to the clinical situation.
Study NCT05455190 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Fit Together
Description: Fit Together intervention follows a clinic and community partnership model for childhood obesity treatment. Children with obesity will receive standard of care obesity treatment from their usual provider and will also receive a referral to an activity program run out of the local community center. Each session delivers a combination of high-intensity individual exercises, sports and games, and unstructured playtime to help children reach the US Physical Activity guidelines of 60min moderate-to-vigorous physical activity daily. There will also be a nutrition activity session offered regularly.
Study NCT05455190 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational materials
Description: Participants will receive a child-friendly cooking magazine mailed quarterly and a local Parks and Recreation program guide.
Study NCT05198154 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ctDNA detection
Description: High-depth sequencing method is used to detecting ctDNA.
Study NCT06292793 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Coping Information
Description: A 4-minute audio recording providing common pain coping techniques (e.g., ice, rest, medication, surgery).
Study NCT06292793 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cyclical Sighing
Description: A 4-minute audio recording consisting of a 1-minute introduction to cyclical sighing followed by a 3-minute cyclical sighing practice.
Study NCT05353296 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital cognitive behavioral therapy for insomnia (CBT-I) program
Description: A self-guided digital program of CBT-I (Somryst) that has been culturally adapted for Spanish-language speakers. Somryst is an interactive and tailored mobile-based program modeled on the primary tenets of face-to-face CBT-I. Patients will be asked to complete six cores (main intervention content) during the 9-week intervention period. The cores provide key content across six domains including behavioral (sleep restriction, stimulus control), cognitive (cognitive restricting), educational (sleep hygiene), overview, and consolidation/relapse prevention.
Study NCT05353296 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Minimally Enhanced Usual Care (mEUC)
Description: A minimally enhanced usual care, which will include usual care by patients' Primary Care Provider and a sleep hygiene brochure.
Study NCT05353296 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Somryst (culturally adapted)
Description: FDA-authorized digital cognitive behavioral therapy for insomnia (CBT-I) trains your brain for better sleep.
Study NCT06338254 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: percussion massage therapy
Description: Pregnant women included in this group received a total of 12 sessions of percussion massage therapy, applied to their bilateral lower extremities for four weeks. Percussion massage was applied to both extremities at separate times for 5 minutes each with the Hypervolt device. (Fig. 2) Four muscles in total were focused on; These muscles are medial gastrocnemius, lateral gastrocnemius, peronus longus, and tibialis anterior. Percussion massage was applied in the longitudinal direction of the muscle, from distal to proximal and back to distal, going from posterior to anterior muscle groups. Percussion massage started on the medial side and ended on the lateral side for each muscle. Equal pressure and duration were applied to each muscle.
Study NCT04785586 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Weight Coaching
Description: Lifestyle intervention based on Healthy Weight Coaching (HWC) is a 52 week long web-based weight loss program consisting of weekly modules, exercises, peer support, and one-on-one coaching. It encompasses themes such as diet, physical activity, coping with stress, sleep, and general health.
Study NCT04785586 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Healthy Weight Coaching
Description: Lifestyle intervention based on Healthy Weight Coaching (HWC) is a 52 week long web-based weight loss program consisting of weekly modules, exercises, peer support, and one-on-one coaching. It encompasses themes such as diet, physical activity, coping with stress, sleep, and general health.
Study NCT04785586 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individual meetings
Description: Individual sessions via video, offered to the participant at three (3) different time points during the 12 month intervention.
Study NCT04785586 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group meetings
Description: Group sessions via video, offered to the participant at three (3) different time points during the 12 month intervention.
Study NCT05715502 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: brachytherapy
Description: Radiation: focal low dose rate or high dose rate brachytherapy for the lesion with appropriate margin, defined in magnetic resonance or positron emission tomography All recruited participants will be treated with interstitial brachytherapy for local recurrence of prostate cancer. The low dose rate of brachytherapy is used with a total dose of 145 Gy in the clinical target volume for participants after hypofractionated radiotherapy, a high dose rate brachytherapy as monotherapy or boost with external beam radiotherapy The high dose rate brachytherapy with two fractions of 13 Gy in the clinical target volume with a 3 to 14 days break is used after primary low dose rate brachytherapy or external beam radiotherapy alone.
Study NCT05532683 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Behaviors Group
Description: The proposed intervention will include eight modules across nine weekly group sessions targeting psychoeducation of CHR-P symptoms, goal setting, physical activity, sleep, substance use, nutrition, and evidence-based strategies for stress management. Intervention facilitators will utilize motivational interviewing (MI; Miller \& Rollnick, 2012) strategies to engage youth in goal setting to target change in health promotion behaviors. Caregivers will be invited to join at the end of each session for a 10-minute check-out where an outline of content covered and patient goals for the week will be shared.
Study NCT05674877 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Opioid-based group (OB) (placebo/saline)
Description: Patients in the opioid-based group will receive placebo boluses and infusions of saline.
Study NCT05674877 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Opioid sparing group (OS) (dexmedetomidine (PRECEDEX™ dexmedetomidine hydrochloride - Pfizer) and ketamine)
Description: Patients in the Opioid Sparing group will receive a dexmedetomidine (PRECEDEX™ dexmedetomidine hydrochloride - Pfizer) and ketamine.
Study NCT06277024 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination of Cardonizumab with Lenvatinib and SOX regimen
Description: Phase 1: Conduct a ramp up test on the dosage of lenvatinib according to the traditional 3+3 design; Phase 2: 6 cycles of treatment with candenizumab+lenvatinib+SOX regimen (Q3W); For patients who have not progressed, they will enter the third stage of maintenance treatment.~Phase 3: Maintenance therapy with candenizumab, lenvatinib, and tigio (Q3W).
Study NCT05294159 — intervention group
Intervention type: OTHER
Intervention: The Feasibility of Intervention Measure (FIM) and Acceptability of Intervention Measure (AIM)
Description: The Feasibility and Acceptability of Intervention Measure (FIM and AIM) are used to evaluate the feasibilit and acceptability of our implementation strategies. The FIM and AIM is a validated implementation outcome measure where higher scores indicate greater feasibility and acceptability
Study NCT05928559 — intervention group
Intervention type: OTHER
Intervention: OMRON BF511 Body Composition Monitor
Description: The OMRON BF511 Body Composition Monitor is a digital scale and participants' body compositions will be evaluated with this device. The aerobic capacities of the participants will be evaluated with the Multi-Stage 20 m Shuttle Run Test and the maximum oxygen consumption levels will be calculated with the help of the formula with the data obtained from this test. The trunk extensor muscle endurance of the participants will be evaluated with the Biering-Sorensen Test and the trunk flexor endurance will be evaluated with the Kraus-Weber Test. Participants' M. Quadriceps, M. Hamstring, M. Biceps Brachii and M. Triceps Brachii muscle strengths will be evaluated with MicroFET® 2 hand dynamometer.
Study NCT04742660 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ammonium Glycyrrhizinate
Description: In control group, we assess the incidence and severity of PONV when participants are aministered ramosetron and placebo. In intervention group, the outcomes are assessed as a result of administration of ramosetron and glycyrrhizin.
Study NCT04742660 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ammonium Glycyrrhizinate
Description: In control group, we assess the incidence and severity of PONV when participants are aministered ramosetron and placebo. In intervention group, the outcomes are assessed as a result of administration of ramosetron and glycyrrhizin.
Study NCT05908331 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sirolimus Drug Coated Balloon
Description: Magic TouchTM (Concept Medical) is a semi-compliant sirolimus drug coated balloon (SCB) for PCI, based on a polymer-free and nanocarrier based drug delivery technology.
Study NCT05908331 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Plan balloon Angioplasty (POBA)
Description: Plan balloon used to open clogged or narrow coronary arteries due to underlying atherosclerosis
Study NCT05039567 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: optimal heart team protocol
Description: Heart teams in the experimental group will be established and trained based on the optimal heart team implementation protocol. The protocol included instructions on specialist selection, specialist training, team composition, team training and formal implementation precess.
Study NCT05745467 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Povidone Iodine 5% Soln,Top,Kit
Description: 5% povidone iodine will be swabbed in patients nares of the experimental group.
Study NCT02014220 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment
Study NCT05345847 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active Surveillance
Description: Close monitoring of liver enzymes with steroid rescue strategy (watch and wait approach)
Study NCT05345847 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Early initiation
Description: Immediate start of high-dose steroids
Study NCT06095635 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Protocol
Description: ingestion of 500 mg of starch following 30 minutes of exercise (treadmill)
Study NCT06095635 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protocol Beet
Description: ingestion of 500 mg of beet extect following 30 minutes of exercise (treadmill)
Study NCT06095635 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protocol Resveratrol
Description: ingestion of 500 mg of resveratrol following 30 minutes of exercise (treadmill)
Study NCT06095635 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protocol Beet and Resveratrol
Description: ingestion 500 mg of beet extect and 500 mg of resveratrol following 30 minutes of exercise (treadmill)
Study NCT04231396 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Audiobooks for hearing loss App
Description: Same as Arm 1
Study NCT05259410 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TRE
Description: All food eaten within the same self-selected 8 hour eating window daily, water fasting the remaining hours of the day.
Study NCT04770740 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin K2 in the form of Menaquinone-7 (MK-7)
Description: Patients will take three tablets of vitamin K2 menaquinone-7 (333mcg) per day. Patients taking vitamin K2 MK-7 will receive the total of 999mcg per day from day 1 until day 14 or discharge, whichever occurs earlier. All subjects can be treated with prophylactic or therapeutic heparin-based (heparin or any low-molecular weight heparin) anticoagulants, according to local hospital protocols. Provided by Kappa Bioscience.
Study NCT04770740 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will take three tablets of placebo containing only inactive ingredients per day, from day 1 until day 14 or until discharge, whichever occurs first. The placebo is provided by Kappa Bioscience.
Study NCT05259410 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MedTRE
Description: A mediterranean style diet will be eaten within the same self-selected 8 hour eating window daily, water fasting the remaining hours of the day.
Study NCT06425094 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Microalgae Extract Capsules
Description: Tetrasol extract
Study NCT06425094 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: maltodextrin \& vegetable magnesium stearate
Study NCT06310226 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Epidural electrical spinal cord stimulator
Description: Epidural electrical spinal cord stimulator turned on vs. turned off
Study NCT06316778 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic floor muscle training
Description: 12 weekly sessions of 60 minutes with an experienced physiotherapist, including pelvic floor muscles (PFM) exercises with biofeedback, teaching home exercises and education.
Study NCT06124183 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals
Description: The program is based on the emotional intelligence skills model (Mayer \& Salovey, 1997; Salovey \& Mayer, 1990), which suggests that emotional intelligence consists of four hierarchical branches or components: (a) perception of emotions, (b) facilitating thinking using emotions, (c) understanding emotions, and (d) managing and handling emotions. The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals. The sessions follow a similar structure, involving session framing, motivation on the central theme, group activity for sharing ideas and experiences, individual activities, review, and task assignment. The first and second sections focus on analyzing the personal reality and current emotional conditions of the participants, while the final session is designed for both celebration and program evaluation. The remaining nine sessions address the four branches of the skill model.
Study NCT06124183 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals
Description: The program is based on the emotional intelligence skills model (Mayer \& Salovey, 1997; Salovey \& Mayer, 1990), which suggests that emotional intelligence consists of four hierarchical branches or components: (a) perception of emotions, (b) facilitating thinking using emotions, (c) understanding emotions, and (d) managing and handling emotions. The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals. The sessions follow a similar structure, involving session framing, motivation on the central theme, group activity for sharing ideas and experiences, individual activities, review, and task assignment. The first and second sections focus on analyzing the personal reality and current emotional conditions of the participants, while the final session is designed for both celebration and program evaluation. The remaining nine sessions address the four branches of the skill model.
Study NCT04531878 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4-Phenylbutyrate
Description: 4-phenylbutyrate therapy will be started at a daily dose of 200 mg kg/d divided in 2 oral doses of sodium phenylbutyrate (AMMONAPS, Swedish Orphan Inter AB). In order to get the best effect, the dose will be increased up to a maximum of 500 mg kg/d.
Study NCT05545020 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Trivalent chromium versus synthetic and/ or biological DMARDs
Description: Supplement and immunesuppressants
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 1
Description: This session will have 3 editions in which the 50 participants of the experimental group will be distributed, with about 16 to 17 participants per edition.~Its objective is to know the group and their expectations, in addition to providing basic knowledge about diabetes and a healthy lifestyle.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 2
Description: The sessions for the 5 groups will take place within 2 weeks. Two weeks after the 1st session, the 2nd session-workshop will be scheduled with no more than 10 participants. For this, 5 groups will be made. An attempt will be made to ensure that the participants in the groups remain stable.~Its objective is to pave the way for the change to a healthy eating lifestyle and provide patients with sufficient knowledge so that with theory they can prepare a daily group menu according to the caloric needs of each of the participants.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 3
Description: Its general objective is to motivate the change towards healthy eating. And the specific ones develop a weekly menu according to calorie needs.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 4
Description: Its general objective is to reinforce a healthy lifestyle-eating, and the specific ones are to learn to read labels, preparing a weekly menu in a group.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 5
Description: Its general objective is to reinforce lifestyle-physical activity. And the specific objectives are to recognize that it is a moderate physical activity and the goal to achieve of recommended physical activity per week and plan a week of physical activity.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 6
Description: Its general objective is to reinforce a lifestyle-healthy eating and physical activity. And the specific ones are to reinforce the concept of physical activity in diabetes, what to do with hypoglycemia and adjust diet and exercise to current weight and needs.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 7 to 8
Description: The objective will be to maintain a healthy lifestyle and adjust menus and physical activity to current caloric needs, in addition to sharing experiences.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group session 9
Description: In the final session, a certificate of adherence to healthy living will be delivered, reminding you to continue with the acquired habits and attend scheduled consultations and tests.~The days of the sessions are indicative, but they must be held in the week when the specified period of time between session and session is met.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Intervention 1
Description: They will be given written information about the convenience of moderate physical activity and they will be informed of the importance of following an appropriate diet for diabetes and we will encourage weight loss.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Intervention 2
Description: Your controls will be carried out according to the usual diabetes protocol established in the individual scheduled diabetes consultation reviews.
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Intervention 3
Description: These patients will also be given a written document about living with diabetes, advice on physical activity, and a pre-established diet will be given according to the number of calories needed previously calculated
Study NCT06222775 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Intervention 4
Description: In addition to verbal recommendations. This document will be made after the act of assigning the control or experimental group.
Study NCT05621213 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Teleconsultation assisted by a physiotherapist or nurse
Description: A home health care provider (with expertise in NIV) will be asked to attend the 2 home teleconsultation sessions.~This assistance will make it possible to help, if necessary, the patient to settle in and connect, collect the elements necessary for the doctor's consultation and adjust, if necessary, the NIV settings. He will also be responsible for administering the questionnaires to the patient as well as to his family caregiver.