AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06027632 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cognitive exercises without supervision
Description: Patient will have access to the program named PRESCO of the HAPPYNeuron-Pro software, which is designed to train up to 12 different cognitive domains, including attention, memory, executive functions and processing speed
Study NCT04731025 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gentamicin, Cefazolin and Vancomycin
Description: The antibiotic solution will contain 1000 mg vancomycin, 80 mg gentamicin and 1000 mg cefazolin in a 500 mL isotonic saline solution. The solution will be used to wash the dissected implant pocket and the implant prior to insertion in the implant pocket.
Study NCT04731025 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 500 mL of sterile isotonic (9%) saline. The solution will be used to wash the dissected implant pocket and the implant prior to insertion in the implant pocket.
Study NCT03083431 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Oral propranolol (1.6 mg propranolol-hydrochloride/kg/d in 4 divided dosages)
Study NCT03083431 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral solution containing the same excipients as propranolol solution
Study NCT05940896 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Disitamab vedotin
Description: Disitamab Vedotin intravenously combined with radiotherapy (concurrent)
Study NCT06228872 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cognitive Computerized Training (CCT) plus Anodic transcranial Direct Current Stimulation (tDCS)
Description: Computerized Cognitive Training (15 min) + Anodal tDCS over DLPFC (20 min) daily for 1 month
Study NCT06228872 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Cognitive Computerized Training (CCT) plus sham transcranial Direct Current Stimulation (tDCS)
Description: Computerized Cognitive Training (15 min) + Sham tDCS over DLPFC (20 min) daily for 1 month
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS5091 Tablets
Description: HRS5091 Tablets once daily
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Maleate Tablets
Description: Midazolam Maleate Tablets single dose
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin Sodium Tablets
Description: Warfarin Sodium Tablets single dose
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole Enteric Capsules
Description: Omeprazole Enteric Capsules single dose
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin K1 Tablets
Description: Vitamin K1 Tablets once daily
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Digoxin Tablets
Description: Digoxin Tablets single dose
Study NCT05273775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin Calcium Tablets
Description: Rosuvastatin Calcium Tablets single dose
Study NCT05323188 — intervention group
Intervention type: OTHER
Intervention: Tryptase dosage
Description: Collection of biological waste from a blood test for complete blood count (CBC) of care. Centrifugation to recover the plasma, then dosage of the tryptase.
Study NCT04769505 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: digital mindfulness-based intervention (MBI)
Description: The digital MBI consists of four auditory guided mindfulness exercises lasting between 10 and 15 minutes. The four exercises are a body scan and three sitting meditations (awareness of the heartbeat, awareness of the body, awareness of sounds). The exercises can be conducted via a software (https://www.movisens.com/de/produkte/movisensxs/) on participants' smartphones. Participants will be familiarized with the concept of mindfulness and the intervention in a single face-to-face introductory session. Additionally, participants will receive a manual, containing all relevant information. Participants will be instructed to practice at least once daily over the course of eight weeks. We recommended to come up with a fixed time point for the mindfulness practice to facilitate a routine. They can choose individually between the exercises. After the intervention period, participants received the exercises as audio files and could continue practicing.
Study NCT05324280 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture treatment will be performed according to a defined protocol, and includes body and ear acupuncture.
Study NCT05280899 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weight-bearing As Tolerated
Description: The WBAT group will be instructed to bear weight as tolerated immediately following their surgical procedure. The rehabilitation protocols provided will be identical beyond the initial weightbearing recommendations. Following the initial protection phase (three weeks), whereby the two weightbearing interventions will be provided, patients will progress through standardized phases including mobility and neuromuscular retraining, muscle balance and strengthening, functional training, and finally, advanced training for return to work and sport.
Study NCT05280899 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Partial Weight-bearing
Description: The PWB group will be instructed to bear weight to a maximum of 20 lbs of bodyweight on the operative limb for the initial three weeks (termed toe touch), with graduated return to full weightbearing thereafter.
Study NCT05062252 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mirror Medacta Shoulder System
Description: Anatomic total shoulder arthroplasty system
Study NCT05062252 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Medacta Shoulder System
Description: Anatomic total shoulder arthroplasty system - standard configuration
Study NCT06040502 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The DICE Approach
Description: Systematic guidance for care partners through assessment and management of the behavioral and psychological symptoms of dementia
Study NCT06302088 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SAINTS program
Description: A brief descriptive name used to refer to the intervention(s) studied in each arm of the clinical study. A non-proprietary name of the intervention must be used, if available. If a non-proprietary name is not available, a brief descriptive name or identifier must be used.
Study NCT06143059 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ethanol
Description: Sterile, 95% ethanol will be administered through IV infusion
Study NCT06143059 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline is administered as the placebo
Study NCT05602922 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Liu-Zi-Jue Exercise
Description: Combined with the actual situation of stroke patients, this Liu-Zi-Jue Exercise adopts the sitting position.
Study NCT05602922 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Basic treatment +Swallowing rehabilitation training
Description: Basic treatment +Swallowing rehabilitation training
Study NCT05295758 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PAL2
Description: Community health worked based intervention to mitigate psychosocial and life circumstance barriers to optimize health promotion coupled with high blood pressure and lifestyle disease state education~Other Names:~Pragmatic personalized, adaptable approach to lifestyle and life circumstance
Study NCT03869749 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Learning to BREATHE Plus
Description: Activities include psycho-education about stress and emotion regulation, and practices of body scanning, non-aerobic yoga, and meditation, which are designed to cultivate and provide opportunities to practice present-focused, non-judgmental attention.
Study NCT03869749 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health and wellness
Description: The Health Education Wellness Program (modeled after Hey Durham) (Bravender, 2005) will provide didactic information on substance use, nutrition/body image, stress management, exercise, and signs of depression/suicide.
Study NCT05225571 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: there is no any intervention in this study. it is an observational and cross-sectional study.
Study NCT04958902 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
Description: RESTORE (www.restoreonline.ca) includes eight e-modules anticipated to be approximately 30-40 minutes each in length and intended to be completed over 4-8 weeks. The modules address cognitive and behavioural factors posited to cause and maintain psychological distress related to the COVID-19 pandemic. These include cognitions about the cause and meaning of stressors related to the pandemic, including self-blame, other blame and hindsight bias, as well as problematic beliefs related to safety, trust, and control. The modules also address the importance of: (1) expressing emotions that are natural to the events of the pandemic (e.g., sadness in the face of loss), (2) working through, rather than avoiding, thoughts, feelings and grief related to the pandemic, and (3) utilizing social supports. The modules consist of written materials, brief videos, and practice assignments delivered through the platform. RESTORE includes guidance via direct messaging and/or brief telephone calls.
Study NCT04939753 — intervention group
Intervention type: DRUG
Intervention: Sevoflurane
Description: Sevoflurane administration to sedate the patient
Study NCT06247332 — intervention group
Intervention type: OTHER
Intervention: Review of available clinical data sources related to use cases
Description: There will be a review of available clinical data sources related to use cases. In addition, this information will be complemented by a cohort of anonymized retrospective data of 100 cases obtained from the clinical information resulting from the assistance to COVID-19 patients managed by the Primary Care Health District of Sevilla Norte and the Infectious Diseases Department of the Virgen Macarena University Hospital
Study NCT05171868 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing (EMDR)
Description: Each participant in the intervention group will receive 8 individual, weekly EMDR sessions over 8 weeks. Each session will take approximately 60-90 minutes. The sessions will be delivered at a place convenient to the participant. Trained EMDR therapists will deliver the intervention.
Study NCT06211387 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Exercise Training
Description: Resistance Exercise Training for knee
Study NCT06211387 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Resistance Exercise Training
Description: Resistance Exercise Training for knee
Study NCT06211387 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Joint Mobilization
Description: Tibiofemoral and Patellofemoral Joint Mobilization
Study NCT04758234 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3549492
Description: Administered orally.
Study NCT04758234 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally.
Study NCT06179732 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Mesh - spatial repellent impregnated with transfluthrin (2500mg)
Description: Mesh is one of the first spatial repellent tools to provide long-lasting protection to users, with predicted efficacy of 6-months. The active ingredient of Mesh is transfluthrin, a fast-acting volatile pyrethroid with low persistency, which can act either by killing or via sublethal toxicity that causes deviation (repellency) in host attraction, reducing host-contact and risk of infectious bites. The chemical passively releases into the air and interacts with vector odour receptors causing irritation. The design of Mesh is simple with a transfluthrin-infused sheet protected by plastic mesh and encased in a plastic frame.~Mesh will be distributed to the intervention arm only.
Study NCT06179732 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Information and Education Campaigns (IEC)
Description: IEC campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home) using leaflets and word of mouth. IEC will be conducted in both arms.
Study NCT06179732 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: test and treat malaria cases
Description: All children in the cohort (both arms) will be tested by rapid diagnostic testing (RDT) monthly. If any children test positive, they will be treated with a course of 3-day artemisinin combination therapy (ACT) according to standard protocol and local guidelines. All children in the cohort will receive ACT to provide clearance of any malaria parasites during the baseline of the study.
Study NCT05347875 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ICanWALK© App.
Description: App containing educational and instructional videos on crutch fitting and walking with key components of these skills highlighted. App video records individual using the taught skills to enable them and their care providers to review their usage of the walking aids.
Study NCT05207722 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CYNK-101
Description: CYNK-101 is a human placental hematopoietic stem/progenitor cell derived NK cell product, that is genetically modified to express a variant of CD16, Fc gamma receptor III (FcγRIII).
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200 mg on Day 1 of each 3-week cycle as an IV infusion.
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: 8 mg/kg loading dose and then 6 mg/kg maintenance dose administered IV on day 1 of each 3-week cycle.
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human Interleukin-2
Description: 6 million (M) international units (IU) of rhIL-2 administered subcutaneously (SC) on each CYNK-101 infusion day.
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Cyclophosphamide: 900 mg/m2 administered IV as part of a 3-day lymphodepletion regimen.
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Fludarabine: 30 mg/m2 administered IV as part of a 3-day lymphodepletion regimen.
Study NCT05207722 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesna
Description: MESNA: shall be administered as part of a 3-day lymphodepletion regimen for the inhibition of hemorrhagic cystitis induced by cyclophosphamide. Route of administration, dosage, and frequency of Mesna should be based on institutional standards.
Study NCT05838950 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high-intensity interval training intervention
Description: Intervention groups include 3 arms with 3 different HIIT protocols to identify optimal exercise regimen for improving cardiometabolic health in young adults with obesity.
Study NCT06448858 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: serum Mn, Se, iron, Cu & Zn levels
Description: Evaluate the concentration of serum Mn, Se, iron, Cu \& Zn levels in obese and overweight adolescents.
Study NCT04775576 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pleth Variability Index
Description: Conventional fluid management is widely used in clinical practice. In this method, the fluid need of the patient is decided according to pulse, arterial blood pressure, central venous pressure, urine output and clinical condition. In the targeted fluid therapy method, besides static parameters such as pulse, arterial blood pressure, central venous pressure; Dynamic parameters such as Stroke volume variability (SVV), pulse pressure variability (PPV), pleth variability index (PVI), continuous hemoglobin (SpHb) are also used noninvasively.
Study NCT04775576 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional fluid theraphy
Description: 8-10 ml / kg / hour iv fluid maintenance will be started for the control group. If the mean arterial pressure (MAP) is \<65 mmHg or the decrease in MAP is more than 20%, 250 ml iv colloid will be applied. If the decrease in MAP continues despite the colloid bolus or if the MAP is below 65 mmHg, noradrenaline infusion will be started.
Study NCT04775576 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Anesthesia method
Description: All patients included in the study will be premedicated with 1mg of midazolam after monitoring with pulse, non-invasive blood pressure, oxygen saturation. Then, invasive arterial cannulation will be applied and continuous blood pressure monitoring will be done. In the PVI group, non-invasive PVI and SpHb monitoring will also be performed from the other upper extremity without arterial cannulation. After two minutes of preoxygenation, anesthesia induction will be started. Anesthesia induction doses used routinely in our clinic include iv 2 mg / kg propofol, 0.6 mg / kg rocuronium and 2 μg / kg fentanyl. Sevoflurane will be administered by inhalation during anesthesia maintenance after tracheal intubation.
Study NCT05048589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard-Dose Quadrivalent Influenza Vaccine
Description: For the control arm, the standard-dose quadrivalent influenza vaccines Influvactetra® and Vaxigriptetra will be used.
Study NCT05048589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High-Dose Quadrivalent Influenza Vaccine
Description: For the control arm, the high-dose quadrivalent influenza vaccine Efluelda®/Fluzone® High-Dose Quadrivalent will be used.
Study NCT04305106 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab (7.5mg/kg BW) + Saline (100ml) Bevacizumab will be administered in a single dose with no less than 90 minutes of intravenous infusion under ECG monitoring.
Study NCT04305106 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (7.5mg/kg BW) + Saline (100ml) The placebo drug will be administered in a single dose with no less than 90 minutes of intravenous infusion under ECG monitoring.
Study NCT04305106 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: Standard care, including prophylactic doses of low molecular weight heparin or unfractionated heparin without contraindications, and therapeutic doses of anticoagulants with the evidence of thrombosis risk or occurrence.
Study NCT04305106 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Standard care
Description: Standard care, including prophylactic doses of low molecular weight heparin or unfractionated heparin without contraindications, and therapeutic doses of anticoagulants with the evidence of thrombosis risk or occurrence.
Study NCT05499078 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SULFEX 13081.22
Description: Patients with dry or irritated nose treated with SULFEX 13081.22 nasal spray for 6 days (with at least 1 spray use a day). Severity of the nasal symptoms will be compared before and 6 days after spray use on a 7-point nasal symptoms scale basis.
Study NCT05548491 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZR-MD-001 ointment/semi-solid drug
Description: ointment/semi-solid drug
Study NCT05548491 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: AZR-MD-001 ointment/semi-solid drug
Description: ointment/semi-solid drug
Study NCT05760222 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture for prevention/early treatment of vasomotor symptoms and sleep impairment in LHRHa induced amenorrhea in Breast Cancer patients
Study NCT04963959 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Peripheral blood mononuclear cell apheresis
Description: mononuclear cell donation for tumor immunotherapy study of UCAR-T cells
Study NCT05422209 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mesh-augmented sacrospinal fixation with posterior colporrhaphy and perineoplasty.
Description: Vaginal mesh-augmented sacrospinal fixation with posterior colporrhaphy and perineoplasty.
Study NCT05422209 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mesh-augmented sacrospinal fixation with posterior colporrhaphy.
Description: Vaginal mesh-augmented sacrospinal fixation with posterior colporrhaphy.
Study NCT04777448 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: telerehabilitation
Description: 24 sessions (less Thant 1h hour each) of tele rehabilitation. Patients can choose among several activities (gym, dance, cardio training, ...)
Study NCT06088251 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutri Training
Description: Nutri Training will begin with 1) a presentation of diet counseling evidence and best practices for advising patients, along with information about nutrition recommendations for patients with chronic illness and 2) tools supporting the patient for follow-up. This content will be delivered via a live demonstration of the Nutri interactive software and case demonstration, a novel approach to delivering the learning objectives of standard nutrition education for residents.
Study NCT06088251 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Nutrition Education
Description: Standard Nutrition Education Standard Nutrition Training will present an overview of 1) nutrition recommendations for patients with chronic disease and 2) cover the role of a registered dietitian and referrals.