AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06071806 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Topical Application of 5-Fluorouracil
Description: The entire cyst lining radically enucleated in conjunction with any overlying mucosa, followed by extensive cavity thorough curettage, peripheral ostectomy was carried out for all bony walls to remove the microscopic satellite cyst, with identification, isolation, retraction, and preservation of the lingual and inferior alveolar bundle,a sterile radiopaque quarter-inch ribbon gauze coated with 5-FU cream was packed into the surgical wound. Closure of the wound was then done in the usual manner using 3/0 vicryl leaving approximately1 cm of a small distal end of the gauze exposed to allow for easy removal after 24 hours postoperatively
Study NCT04924881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: COVID Rehab Formula granules
Description: COVID Rehab Formula granules once daily for 8 weeks
Study NCT04924881 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo granules
Description: Placebo granules once daily for 8 weeks
Study NCT05482100 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Patients monitored with OmniGraf testing
Description: This is an observational study there are no protocol mandated interventions. OmniGraf results will be utilized in conjunction with standard of care assessments to determine patient management.
Study NCT04406857 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Given PO
Study NCT04406857 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Undergo radiation therapy
Study NCT04406857 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropidoxuridine
Description: Given PO
Study NCT05201313 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride
Description: nebulization of 3 puffs of 10 mL Lidocaine hydrochloride 10% spray at a distance of 4-5 cm
Study NCT05201313 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mepivacaine Injection
Description: subcutaneous / submucosal infiltration depending on the type of perineal tear of 10 ml of 1% mepivacaine hydrochloride
Study NCT05237076 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Hyperinsulemic-Euglycemic Clamp & Hypoxic Ventilatory Response (HVR)
Description: Hyperinsulemic-Euglycemic Clamp as described by deFronzo et al.
Study NCT05237076 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Hyperinsulemic-Euglycemic Clamp & Hypoxic Ventilatory Response (HVR)
Description: Hyperinsulemic-Euglycemic Clamp as described by deFronzo et al.
Study NCT06226493 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous vagus nerve stimulation
Description: The Parasym Plus device (https://parasym.io) is a transcutaneous auricular vagus nerve stimulator that has been deemed non-significant risk (NSR) by the FDA. Transcutaneous auricular vagus nerve stimulator is a non-significant risk device, as it involves electrical stimulation of the external ear using an ear clip, with no invasive components. The stimulation parameters will be limited to the confines of existing published data. tVNS is safe and well tolerated at doses tested in research studies. The Parasym device is considered low risk when used in accordance with the instructions for use. Participants will be properly trained to use the device, and those with contraindications will be excluded for extra precaution. A low incidence of skin irritation has been reported. No serious adverse events have been reported.
Study NCT05635253 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Hydrogen Peroxide 35%
Description: Group that received only bleaching treatment. Soft tissue protection was performed with a Top Dam light-curing gingival barrier (FGM, Santa Catarina, SC, Brazil). Application of whitening gel (Whitness HP 35%/FGM) on the buccal surface from premolar to premolar in the upper and lower arches. Three 45-minute sessions were held with an interval of seven days between them.
Study NCT05635253 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hydrogen Peroxide 35% + Polishing whitened teeth
Description: Group that received only bleaching treatment followed by polishing. Soft tissue protection was performed with a Top Dam light-curing gingival barrier (FGM, Santa Catarina, SC, Brazil). Application of whitening gel (Whitness HP 35%/FGM) on the buccal surface from premolar to premolar in the upper and lower arches. Three 45-minute sessions were held with an interval of seven days between them. After bleaching, the vestibular surfaces were polished for 20s on each bleached tooth, with polishing paste and felt disc (Diamond Flex, FGM, Santa Catarina, SC, Brazil) in low rotation.
Study NCT05377255 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: 16 mg naloxone AP003
Description: 4 doses of 4 mg each (total: 16 mg) of naloxone through the AP003 device
Study NCT05377255 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: OTHER
Intervention: 8 mg naloxone NARCAN Nasal Spray
Description: 2 doses of 4 mg each (total: 8 mg) of the naloxone through the NARCAN Nasal Spray device
Study NCT06517589 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Process-based Cognitive Behavioral Therapy (PBT)
Description: PBT (20 sessions), intervention planning based on the use of EMA data, feedback of dynamic network analysis and matching of interventions to central nodes of the network.
Study NCT06517589 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy (CBT)
Description: CBT (20 sessions), intervention planning as usual based on manual.
Study NCT06003270 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Quercetin 1000 mg
Description: Active comparator
Study NCT06003270 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Quercetin 500 MG
Description: Active comparator
Study NCT06003270 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo comparator
Study NCT05724095 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high frequency acupoint stimulation
Description: electrodes are attached to area of acupoints and electrical stimulation at 10/50 Hz is given
Study NCT05724095 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: low frequency acupoint stimulation
Description: electrodes are attached to area of acupoints and electrical stimulation at 2/10 Hz is given
Study NCT05724095 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: electrodes attached
Description: electrodes are attached to area of acupoints
Study NCT05724095 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: electrodes attached
Description: electrodes are attached to area of acupoints
Study NCT05166200 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Formula
Description: Diabetes-specific study formula
Study NCT05166200 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Test Meal
Description: Instant oatmeal
Study NCT06061549 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AAV1/SERCA2a
Description: 3E13 viral genomes fixed dose
Study NCT05536765 — intervention group
Intervention type: PROCEDURE
Intervention: Surgical exposure of impacted tooth
Description: The therapeutic approach of surgical exposure of impacted teeth is performed by preparing a flap and removing the cortical bone around the crown of the teeth.~This procedure provides optimal conditions for the orthodontist. In fact, surgical exposure allows the orthodontist to bond the impacted tooth in the correct position depending on the intended direction to apply the correct traction forces for alignment.
Study NCT04543279 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fostamatinib
Description: Fostamatinib will be supplied by Rigel Pharmaceuticals.
Study NCT04543279 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib
Description: Ruxolitinib is commercially available.
Study NCT06437041 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ornidazole
Description: Patients will receive three consecutive enemas of ornidazole 0.5g+50ml saline through the TET tube, followed by WMT treatment once daily for a duration of 3 days.
Study NCT06437041 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive three consecutive enemas of placebo of equal volume through the TET tube, followed by WMT treatment once daily for a duration of 3 days
Study NCT05717543 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Retro-illuminator
Description: The device Retro-illuminator will be used to photograph the eyes.
Study NCT05915910 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Specimen Donation
Description: blood donation
Study NCT06331143 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultrasound-Guided Mid-Transverse Process to Pleura (MTP) Block
Description: Patients will receive MTP block after induction of anesthesia.
Study NCT06331143 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: Patients will receive intrathecal morphine in a dose of 12 μg/kg (max 1000 μg) immediately after induction of anesthesia.
Study NCT05481086 — intervention group
Intervention type: OTHER
Intervention: No Interventions
Description: There is no interventions in this study
Study NCT06073301 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acellular Fish Skin Graft (AFS) with Standard of Care Negative Pressure Wound Therapy (NPWT)
Description: Acellular Fish Skin, used to temporize a wound bed prior to autograft. The intention is to prepare the wound bed for optimal autograft take.
Study NCT06073301 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acellular Human Cadaver (AHC) with Standard of care Negative Pressure Wound Therapy (NPWT)
Description: Acellular Human Cadaver , used to temporize a wound bed prior to autograft. The intention is to prepare the wound bed for optimal autograft take.
Study NCT05836896 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: MDC-CAR-BCMA001 (BCMA directed CAR T-cells)
Description: Single-dose intravenous infusion of MDC-CAR-BCMA001 at the respective dose level following a conditioning chemotherapy
Study NCT06410196 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Mood modulation
Description: Autobiographical memory recall designed to modulate mood and affective state by reminiscing about personal life events
Study NCT06410196 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mood modulation
Description: Autobiographical memory recall designed to modulate mood and affective state by reminiscing about personal life events
Study NCT05576454 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mepolizumab Injection (BAT2606 Injection)
Description: In this group, each subject will receive single subcutaneous injection of 100 mg BAT2606 Injection.
Study NCT05576454 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mepolizumab Injection (EU-licensed Nucala)
Description: In this group, each subject will receive single subcutaneous injection of 100 mg Mepolizumab Injection (EU-licensed Nucala®).
Study NCT05576454 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mepolizumab Injection (US-licensed Nucala)
Description: In this group, each subject will receive single subcutaneous injection of 100 mg Mepolizumab Injection (US-licensed Nucala®).
Study NCT06116370 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rezum procedure
Description: In Rezūm procedure, the Rezūm System (NxThera Inc., Maple Grove, MN, USA) consists of a radiofrequency (RF) power supply generator and single-use transurethral delivery device. Starting 1 cm distal to the bladder neck, injection was done at 3 and 9 o'clock sites. The needle was inserted for 9 s duration, retracted, and then delivered to another treatment site in 1 cm distance distal to the previous one.
Study NCT06116370 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: B-TURP procedure
Description: In B-TURP, Olympus SurgMaster™ UES-40 bipolar generator (Olympus Europe, Hamburg, Germany) was used. Current's settings used were cut/coag 200/120. Using continuous flow 26Fr resectoscope first resection of the median lobe from the level of the bladder neck to the apex of the prostate was done followed by resection of the lateral lobes. Using Ellic evacuator, Prostatic chips were extracted from the field. A 22 fr three-way silicon Foley catheter was placed with traction applied and the balloon inflated by normal saline of 30-80 cc according to the size of the prostate.
Study NCT05021861 — intervention group
Intervention type: DRUG
Intervention: Cyproterone Acetate, Ethinyl Estradiol Drug Combination
Description: FEMALE PATIENTS WITH PCOS ON CPA/EE DRUG REGIMEN FOR ATLEAST 6 MONTHS
Study NCT05021861 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: FEMALE PATIENTS WITH PCOS
Description: FEMALE PATIENTS WITH PCOS( NEWLY DIAGNOSED) ,NOT ON ANY MEDICATION,
Study NCT05021861 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Control group
Description: SYSTEMICALLY HEALTHY FEMALES
Study NCT06347120 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: nasogastric tube
Description: nasogastric tube (NGT), intravenous administration of fluids, and clinical and biochemical monitoring for 72h.
Study NCT06347120 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NOM without NGT insertion
Description: intravenous administration of fluids, nill per os, analgesic, antiemetic treatment, and clinical and biochemical monitoring for 72h
Study NCT05779189 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Game-based virtual reality (Game)
Description: Besides reading the health education flier, they also need to trained with the game-based virtual reality in Biodex Medical Systems, which is a machine, includes 4 games: Catch Game, boating, Ball Maze, and Word Search. And all of the games are balance control games. The games were implemented in person for 30 minutes one time, total is 16 times (once to twice day a week).
Study NCT05779189 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional health education
Description: The health education flier was made refer to medical institutions, e.g., hospitals or clinics, the video of balance exercise was collected from the internet. Participants were assigned to read the health education flier, and follow suit the video of balance exercise at home of their free will.
Study NCT05702606 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Radial extracorporeal shock wave therapy (rESWT)
Description: Radial shock waves are ballistic waves generated by injection of compressed air inside an applicator that fires a projectile into the itself and impacts against the application head
Study NCT05702606 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Radial extracorporeal shock wave therapy (rESWT)
Description: Radial shock waves are ballistic waves generated by injection of compressed air inside an applicator that fires a projectile into the itself and impacts against the application head
Study NCT06516536 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MBI (Mindfulness-Based Intervention)
Description: Breath-Focused Meditation Approach (5-7 minutes):~They will be guided to observe the flow of air in and out of the nose, noting sensations in the abdomen or chest.~Body scan (7-8 minutes):~Students will be guided through a careful exploration of their body. You'll start with your toes and slowly work your way toward your head, paying attention to the physical sensations in each part of your body.~Simple yoga poses (5-7 minutes):~Students will stand and follow instructions to perform a series of simple poses, such as mountain pose, tree pose, and cat-cow pose.
Study NCT05716282 — intervention group
Intervention type: OTHER
Intervention: Accuracy of neuromuscular recovery estimation
Description: Accuracy of the estimation of neuromuscular recovery will be measured as:~* Correct attribution of the patients to the groups slow, intermediate or fast recovery~* Real speed of recovery falls between 95 confidence interval of the estimated speed of recovery
Study NCT05601895 — intervention group
Intervention type: DRUG
Intervention: Sorafenib
Description: The initial dose of sorafenib is 400 mg orally twice daily and is adjusted in case of suspected toxicity or resistance (dose range, 200-800 mg daily).
Study NCT05069493 — intervention group
Intervention type: PROCEDURE
Intervention: simple suturing
Description: Hiatal hernia repair by simple suturing of the diaphragmatic
Study NCT05069493 — intervention group
Intervention type: PROCEDURE
Intervention: mesh
Description: Hiatal hernia repair by tension-free mesh closure
Study NCT04836780 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone base 6 mg once daily for seven days
Study NCT04836780 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Dexamethasone base 6 mg once daily for seven days
Study NCT04674761 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Odevixibat
Description: Odevixibat is a small molecule and selective inhibitor of IBAT.
Study NCT04674761 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo identical in appearance to experimental drug (odevixibat).
Study NCT04061330 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: Initial bolus of ketamine 0.3 mg/kg IV (maximum 30 mg) followed by ketamine infusion of 0.25mg/kg/hr (maximum 25mg/kg/hr) for 6 hours or until patient leaves the emergency department (ED),whichever occurs first.
Study NCT04061330 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Bolus doses of morphine 0.1 mg/kg (maximum 8 mg) intravenously every 2 hours for 6 hours or until patient leaves the ED, whichever occurs first.
Study NCT04921072 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Constant practice conditions
Description: CG will be practicing only one specific pattern of step isometric contractions (SPSIC) scheme. It means that 90 trials in all training sessions will consist only of SPSIC 1.
Study NCT04921072 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Variable practice conditions
Description: VG will practice three SPSIC's (1-3). Each SPSIC will be practiced 30 times per session, which means that each session will consist of 90 SPSIC like CG.
Study NCT05221957 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iron(III)isomaltoside
Description: Individual weight and hemoglobin dependent dosage
Study NCT05812729 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: resiLIR Basic
Description: Each module contains psychoeducational elements as well as practical exercises.~Week 1: Introduction + Stress and resilience~Week 2: Optimism~Week 3: Mindfulness~Week 4: Sense of coherence and values~Week 5: Acceptance~Week 6: Self-compassion + Conclusion
Study NCT05556811 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic Light Therapy Device, LSA-1
Description: Dynamic Light Therapy
Study NCT05556811 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic Light Therapy Device, LSA-2
Description: Dynamic Light Therapy
Study NCT05556811 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic Light Therapy Device, LSA, 3
Description: Dynamic Light Therapy
Study NCT06653179 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacral Erector Spinae Plane Block
Description: The patient is placed in the prone positionon a procedure table. The sacral region is exposed, and the area is prepped with antiseptic solution under sterile conditions. The ultrasound high-frequency linear transducer is placed transversely over the sacrum. The sacral cornua are typically seen as bony structures adjacent to the sacral hiatus, appearing as two hyperechoic structures. Rotate the ultrasound probe to a sagittal position over the sacrum to align with the fourth and fifth sacral vertebrae. Under continuous ultrasound guidance, block needle is inserted in-plane with the ultrasound probe. Direct the needle through the soft tissue towards the plane between the erector spinae muscle and the sacrum. After confirming needle placement, the injectate mixture of 8 mg dexamethasone and 10 mg bupivacaine (0.5% concentration) is administered. A total volume of 10 mL is injected, and real-time ultrasound is used to observe the spread of the injectate within the target tissue plane.
Study NCT06653179 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Caudal Epidural Injection
Description: The patient is positioned in the prone position on the procedure table, and the sacral region is exposed and prepped with antiseptic solution under sterile conditions. The fluoroscope is positioned laterally to visualize the sacral hiatus. Under fluoroscopic guidance, the block needle is inserted through the skin and advanced toward the sacral hiatus. Continuous fluoroscopy is used to ensure correct needle placement, typically visualized at the level of the sacral canal. After confirming the appropriate position with contrast media, the injectate consisting of 8 mg dexamethasone and 10 mg bupivacaine (0.5% concentration) is slowly administered, with a total volume of 10 mL. During injection, careful monitoring of the needle position is performed to avoid intravascular injection. After the procedure, patients are monitored for potential complications such as hypotension and allergic reactions.