AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06450548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Parametric acquisition
Description: Parametric acquisition for 18F-FDG PET/CT and 68GA-PSMA PET/CT with 24 h at 15 days of interval
Study NCT05897879 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Nasopharyngeal swab
Description: For hospitalized patients :~Nasopharyngeal swab (1 aspiration or 2 swabs (1 in each nostril))~For ambulatory patients :~Deep nasal swab: 2 swabs (1 in each nostril), or 1 swab only for children for whom taking 2 swabs is complicated.
Study NCT05897879 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood samples
Description: For hospitalized patients : 3 to 7.5 ml For ambulatory patients: Fingertip blood sampling
Study NCT05548582 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen 500 mg Tab
Description: Standard prescription
Study NCT05687279 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVt Vaccine
Description: Pharmaceutical Form: Suspension of virus in a nasal spray Route of Administration: Intranasal
Study NCT05548582 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Acetaminophen 500 mg Tab
Description: Standard prescription
Study NCT05548582 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ibuprofen 600 mg
Description: Standard prescription
Study NCT05041270 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: normal saline
Description: Surgery will be started under spinal anesthesia. When sensory block regress to T12 dermatome Epidural bolus dose will be given epidural bolus dose of 12ml (10ml 0.25% bupivacaine + 2ml normal saline) The onset of sensory blockade injected epiduraly with maximal cephalic spread will be assessed by bilateral pinprick method along the midclavicular line, every 5 min for 30 min and then every 30 min.~top up dose of 8ml will be given postoperative (6ml 0.25% bupivacaine + 2ml normal saline).
Study NCT05548582 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Ibuprofen 600 mg
Description: Standard prescription
Study NCT05041270 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Surgery will be started under spinal anesthesia. When sensory block regress to T12 dermatome Epidural bolus dose will be given epidural bolus dose of 12ml (10ml 0.25% bupivacaine + 100µg dexmedetomidine in 2ml volume) The onset of sensory blockade injected epiduraly with maximal cephalic spread will be assessed by bilateral pinprick method along the midclavicular line, every 5 min for 30 min and then every 30 min.~top up dose of 8ml will be given postoperative (6ml 0.25% bupivacaine + 20µg dexmedetomidine in 2ml volume).
Study NCT05041270 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nalbuphine
Description: Surgery will be started under spinal anesthesia. When sensory block regress to T12 dermatome Epidural bolus dose will be given epidural bolus dose of 12ml (10ml 0.25% bupivacaine + 10mg nalbuphine in 2ml volume) The onset of sensory blockade injected epiduraly with maximal cephalic spread will be assessed by bilateral pinprick method along the midclavicular line, every 5 min for 30 min and then every 30 min.~top up dose of 8ml will be given postoperative (6ml 0.25% bupivacaine + 2mg nalbuphine in 2ml volume).
Study NCT06361017 — intervention group
Intervention type: PROCEDURE
Intervention: endovascular thrombectomy
Description: All individuals were anesthetized, with local or general anesthesia dependent on the cooperation level of the patient. During the procedure, it was mandatory to administer intravenous heparin to maintain the activated clotting time between 250 and 300 s, except for subjects who received intravenous alteplase. The procedures were performed through the femoral artery. The selection of stent retriever type and size, along with any required devices, such as guide wires and catheters, as well as the intervention strategy, was at the interventionists' discretion.
Study NCT06182371 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Disengage the breathing circuit
Description: Disengage the breathing circuit when the position of the patient undergoing thoracic surgery changes
Study NCT04857580 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CTS Device
Description: Coronary cryotherapy is delivered locally on eligible lesions randomized to the treatment using the CTS System.
Study NCT05587192 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-PSMA-1007 PET/CT based on diagnostic model
Description: All enrolled patients will receive 18F-PSMA-1007 PET/CT based USTC diagnostic model before gaining the final pathological diagnosis to be used as experimental arm.
Study NCT04951505 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cefepime-taniborbactam
Description: IV infusion
Study NCT06069947 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: sequential adult left lateral lobe liver transplantation (SALT)
Description: Hemihepatectomy combined with left lateral lobe liver transplantation was performed first, and residual liver resection was performed after the graft grew to a sufficient functional liver volume.
Study NCT06579911 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-frequency micro-ultrasound target biopsy
Description: 1. High-frequency micro-ultrasound (transrectal ultrasound, 29 Hz, ExactVu) of the prostate. If suspicious lesions (PRIMUS >= 3) other than those already detected in multiparametric MRI are found, target biopsy will be performed. Maximum of four cores per lesion.~2. Multiparametric MRI target biopsy (PI-RADS >= 3) of the prostate (transrectal ultrasound, 29 Hz, ExactVu). Maximum of four cores per lesion.~3. Systematic biopsy (twelve cores) of the prostate
Study NCT06579911 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: conventional Multiparametric MRT target biopsy
Description: 1. Multiparametric MRT target biopsy (PI-RADS >= 3) of the prostate (conventional transrectal ultrasound, 8-10 Hz). Maximum of four cores per lesion.~2. Systematic biopsy (twelve cores) of the prostate
Study NCT06426706 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Serratus Posterior Superior Intercostal Plane Block
Description: Before the induction of general anesthesia, under aseptic conditions, serratus posterior superior intercostal plane block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.
Study NCT06426706 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Paravertebral Block
Description: Before the induction of general anesthesia, under aseptic conditions, paravertebral block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.
Study NCT04592822 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: WD-1602
Description: dabigatran etexilate mesylate granules for oral suspension
Study NCT04592822 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pradaxa®
Description: dabigatran etexilate capsules
Study NCT04769258 — intervention group
Intervention type: BIOLOGICAL
Intervention: Pfizer Comirnaty vaccine
Description: COVID 19 vaccines administered to the patients according to the times and modalities established by the Italian National Vaccination Plan. Further vaccines will be evaluated if and when they are available in Italy during the study period.
Study NCT06279169 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heart Sound
Description: In the Heart sound group, this sound will be played to the newborn 5 minutes before Hep B vaccine administration, during the procedure (at 1 minute) and 5 minutes after Hep B vaccine administration
Study NCT06279169 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: White Noise
Description: Musician Osman Orhan's song Bebeğiniz Ağlamasın from his album Kolik will be used for white noise. The volume will be set to 45 db.
Study NCT05687279 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control Group
Description: Pharmaceutical Form: Suspension of virus in a nasal spray Route of Administration: Intranasal
Study NCT05459987 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle changes
Description: Nutritional advice to progressively integrate a moderate-carbohydrate Mediterranean diet with intermittent fasting 16:8 (5 times/week for 12 weeks).~Personalized exercise prescription and training (3 times per week)~Personalized education and motivational interviewing
Study NCT05881590 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hybrid pulmonary rehabilitation
Description: Technology-enabled 8-week pulmonary rehabilitation programme using the Active+me REMOTE App
Study NCT06444399 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deucravacitinib
Description: 6 mg administered orally twice daily for 24 weeks.
Study NCT04690673 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paracetamol
Description: 1 g oral paractamol
Study NCT04690673 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Paracetamol concentration measurements and lipidomic assessment
Description: Paracetamol concentration is measured from saline-, urine-, venous blood- and fingerprick- samples at timely intervals. Also serum lipidomic assessment is performed from venous blood samples.
Study NCT05069623 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VB10.2129
Description: 0.3 mg, 1 mg or 3 mg on Day 0 and Day 21 or 3 mg on Day 0
Study NCT05069623 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VB10.2210
Description: 3 doses (dose to be determined) on Day 0 and Day 21 or highest dose (TBD) on Day 0
Study NCT06281236 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisolone
Description: Prednisolone according to the participant's pre-trial dose, symptoms and inflammatory biomarkers.
Study NCT06281236 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SPI-62
Description: SPI-62 administered once daily.
Study NCT05937295 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fusion-VAC-XS15
Description: FusionVAC-22 peptide will be administered subcutaneously (s.c.) adjuvanted with the Toll-like receptor 1/2 ligand XS15 (50 μg) emulsified in Montanide ISA 51 VG (1:1).~Vaccination will take place every 4 weeks at the beginning of Cycle 1 and 2. A total of two vaccinations are planned.~After 11 months a booster vaccination can be applied depending on T-cell responses.~Immune checkpoint inhibition (ICI):~Atezolizumab (TecentriqTM, Roche Pharma AG) is a humanized immunoglobulin (Ig) G1 monoclonal antibody that targets PD-L1 and will be applied intravenously (i.v.).~The anti-PD-L1 antibody Atezolizumab (TecentriqTM) 1680 mg will be applied every 4 weeks as a 30-minute infusion (60-minute first dose) starting on day 15 after the first vaccination. Anti-PD-L1 treatment will be continued after the end of vaccination phase throughout the complete study period until End of Treatment (EOT) or until disease progression or other reasons for study termination.
Study NCT05225558 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Delpazolid
Description: BID, PO
Study NCT06493617 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cervical Mobilization
Description: The technique is used to mobilize a specific cervical or upper thoracic segment (C2-C3 through T3-T4) in a posterior to anterior direction. The therapist gently applies pressure in an anteroposterior direction in the plane of the facet joint to assess mobility, resistance, end feel, and pain provocation. Gentle oscillations can be used to either inhibit pain (grades I and II) or restore motion (grades III and IV). Slight variations in depth and direction of force can be used to optimize the therapeutic effects of this technique.
Study NCT06493617 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy treatment
Description: tendon gliding exercises, median nerve gliding exercise, strengthening exercises for 60 minutes
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CRAFT Web-Based Intervention
Description: Session 1 addresses CPs' mental health issues and drinking. CPs select reasons why they are seeking help and steps they will take towards those goals. Session 2 is focused on improving their relationship through communication exercises. Session 3 is focused on functional analysis of their partner's drinking, and how to positively reinforce their partner's sobriety and negatively reinforce their drinking. Finally, Session 4 focuses on continuing self-care and talking with their partner about their concerns while interacting with them in healthy ways. The WBI contains audio, video, text, and exercises that utilize digital storytelling and vignettes to convey teaching points - a method utilized by the military to address stigma and increase treatment utilization. Actresses portrayed different experiences that the CP may be going through and modeled skills. CPs clicked on the vignette that they most connected with and followed that character across all the sessions.
Study NCT05225558 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin
Description: IV infusion per 2020 IDSA guideline
Study NCT05225558 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vancomycin
Description: IV infusion per 2020 IDSA guideline
Study NCT05225558 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo of Delpazolid
Description: BID, PO
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CRAFT Web-Based Intervention
Description: Session 1 addresses CPs' mental health issues and drinking. CPs select reasons why they are seeking help and steps they will take towards those goals. Session 2 is focused on improving their relationship through communication exercises. Session 3 is focused on functional analysis of their partner's drinking, and how to positively reinforce their partner's sobriety and negatively reinforce their drinking. Finally, Session 4 focuses on continuing self-care and talking with their partner about their concerns while interacting with them in healthy ways. The WBI contains audio, video, text, and exercises that utilize digital storytelling and vignettes to convey teaching points - a method utilized by the military to address stigma and increase treatment utilization. Actresses portrayed different experiences that the CP may be going through and modeled skills. CPs clicked on the vignette that they most connected with and followed that character across all the sessions.
Study NCT05349149 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tocilizumab/Actemra® (Roche)
Description: The infusion of tocilizumab will antagonize IL-6 signaling for the duration of the study, allowing us to determine the role of IL-6 in regulating energy stores following acute exercise
Study NCT05349149 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline 9%
Description: The infusion of saline will serve as placebo for tocilizumab, allowing us to determine the role of IL-6 in regulating energy stores following acute exercise
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phone-Based CRAFT
Description: The phone-based CRAFT intervention consists of six individual sessions with a CRAFT clinician that will explore what they learned from the WBI and additional skills they need. Session content includes positive reinforcement of non-drinking SM behaviors, refraining from interfering in SM's consequences of alcohol use, communication skills, and self-care.
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CRAFT Workbook
Description: The self-directed CRAFT workbook Table 1.Partners Connect WBI has a parent and partner version that uses CRAFT to help the CP help with understanding, self-care, communication, and actions (e.g., how to react when a partner has been using substances and when they have not been using substances, how to talk to partner so that they are more likely to be heard) and includes more information about communicating than the WBI and several interactive worksheets.
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CRAFT Workbook
Description: The self-directed CRAFT workbook Table 1.Partners Connect WBI has a parent and partner version that uses CRAFT to help the CP help with understanding, self-care, communication, and actions (e.g., how to react when a partner has been using substances and when they have not been using substances, how to talk to partner so that they are more likely to be heard) and includes more information about communicating than the WBI and several interactive worksheets.
Study NCT05619185 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gottman Self-Guided Resources
Description: To match time spent reviewing the website, CPs will receive an orientation guide that includes the website URL and a 4-week guide for how they can navigate this website for 20-30 minutes per week (e.g., read article 'It's Not My Fault!': Why Defensiveness is Damaging and write down one tool to dissolve defensiveness you're willing to try). We will send reminder emails each week to visit the website and include questions in the emails and our first online follow-up survey asking CPs approximately how many times they visited the website and how long they spent viewing content on the website. Reminder emails will be programmed such that CPs get directed automatically to the website if the CP notes no time spent on it.
Study NCT06509425 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: salpingectomy during caesarean section
Description: Salpingectomy will be done by clamping, division and ligation using adsorbable suture material (2-0 Vicryl) and excising the tube till it's isthmic part by scissors.
Study NCT06509425 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: tubal ligation during caesarean section
Description: Tubal ligation will be done by Parkland technique. An opening is made in an avascular section of the mesosalpinx by electrocautery. Two absorbable suture ties (2-0 Vicryl) are passed through the opening and used to ligate the proximal and distal ends of the segment (at least 2 cm) which will get excised by scissors.
Study NCT05535803 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Olfactory mucosa-derived mesenchymal stem cells
Description: Autologous olfactory mucosa-derived mesenchymal stem cells
Study NCT05535803 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Patients treated according to current clinical protocols
Description: Patients treated according to current clinical protocols
Study NCT05535803 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patients treated according to current clinical protocols
Description: Patients treated according to current clinical protocols
Study NCT05543980 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham device
Description: The leg heat therapy device consists of a water tank coupled with a circulator, a sous-vide water heater and water-circulating trousers. The water heater in the sham device is adjusted to heat up the water to 33ºC.
Study NCT05543980 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Leg heat therapy device
Description: The leg heat therapy device consists of a water tank coupled with a circulator, a sous-vide water heater and water-circulating trousers. The water heater in the sham device is adjusted to heat up the water to 42ºC.
Study NCT06053983 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Turbox CRP kit
Description: Quantitative estimation of hs-CRP will be conducted at the beginning of the study and after the treatment period using the Turbox CRP kit, which employs turbidimetry as the method of measurement.
Study NCT06053983 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: rosuvastatin 20 mg,
Description: The statin are most commonly used agents for prevention of cardiovascular events and recurrent episodes of ACS. Apart from their anti-lipid actions, statins show pleotropic effects which include their anti-inflammatory role. Atorvastatin and rosuvastatin are both members of statin family and have showed their effectiveness in reduction of inflammatory biomarkers in addition to their lipid lowering effects
Study NCT06053983 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: atorvastatin 40 mg
Description: The statin are most commonly used agents for prevention of cardiovascular events and recurrent episodes of ACS. Apart from their anti-lipid actions, statins show pleotropic effects which include their anti-inflammatory role. Atorvastatin and rosuvastatin are both members of statin family and have showed their effectiveness in reduction of inflammatory biomarkers in addition to their lipid lowering effects
Study NCT05999773 — intervention group
Intervention type: DRUG
Intervention: SGLT2 inhibitor
Description: Start of SGLT-2 inhibitors to treat diabetes according diabetology indications.
Study NCT06340893 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will participate in cardiovascular, agility, balance, strength and coordination training.
Study NCT06340893 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Restful Play
Description: This group will engage in restful play activities such as coloring and playing with legos.