AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06496932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Listen to music
Description: Women in the intervention groups will listen to nature and bird sounds through over-the-ear headphones after spinal anesthesia for cesarean section until the suturing is completed.
Study NCT05172284 — intervention group
Intervention type: OTHER
Intervention: Questionnaires
Description: This is a collection of data from normal clinical routine: patients will be asked to record the assessments they undergo during their course of treatment, without changing clinical practice in any way. Data inherent to the following procedures will be collected: examinations, laboratory tests, imaging tests, questionnaires and rating scales.
Study NCT05183490 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapidly generated virus specific T (R-MVST) cells
Description: The R-MVST products will be manufactured individually for each patient from a selected donor; it is an anti-viral prophylaxis and treatment of viral reactivation.~SCT dose escalation:~Cohort / R-MVST dose~* (-1A) 0.25x10\^6 R-MVST TNC/kg~* (1A) 0.5x10\^6 R-MVST TNC/kg~* (2A) 1x10\^6 R-MVST TNC/kg~SOT dose escalation:~Cohort / R-MVST dose~* (-1B) 1x10\^6 R-MVST TNC/kg~* (1B) 2x10\^6 R-MVST TNC/kg~* (2B) 4x10\^6 R-MVST TNC/kg
Study NCT06167668 — intervention group
Intervention type: OTHER
Intervention: the routine chronic disease management mode
Description: indoor temperature and humidity adjustment, regular ventilation and hygiene of ward and clinic environment, promotion of patients' health awareness by distributing disease brochures, regular inspection of wards, and home nursing and health guidance based on disease knowledge when discharged
Study NCT06167668 — intervention group
Intervention type: OTHER
Intervention: the family-centered family enabling health management mode
Description: The specific measures were as follows :(1) intervention group construction. (2) Online knowledge promotion. (3) Disease assessment.(4) Medication guidance reminder.(5) Enabling psychological counseling.
Study NCT06326515 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: psychoeducation
Description: To identify and recognize the cognitive distortions To explore the automatic thoughts and emotions about illness Evaluate and respond to thoughts, emotions, and beliefs Automatic thought records were used by patients with some help from therapist (Chattopadhyay et al., 2017).~The cognitive errors were corrected using individual cognitive strategies (Chattopadhyay et al., 2017).
Study NCT06326515 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stigma Reduction and Relapse Management
Description: To improve ability to effectively cope with lapse and relapse (Brown \& Vanable, 2008).~To improve relapse management skills (Brown \& Vanable, 2008). Emphasized skill development to cope with OUD-related stressors (Zhang, 2021). To change their conception of OUD (Tshabalala \& Visser, 2011). To change their sense of self-worth and to empower them with more adaptive ways of thinking (Tshabalala \& Visser, 2011).~To deal with their experience of stigma (Tshabalala \& Visser, 2011).
Study NCT05987839 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: robotic system
Description: Total knee arthroplasty assisted by knee navigation and positioning system
Study NCT05307120 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Diameter integrated in secondary diabetes care
Description: Regular T2DM treatment in secondary care will be complemented with the Diameter: a mobile application on smartphones that enables continuous monitoring of physical activity (via activity tracker Fitbit and self-reported activities) and nutrition (via food diary) and blood glucose values (via Freestyle Libre sensor). The Diameter also provides autonomous lifestyle coaching via daily coaching messages, short weekly e-mails and exercises aimed at goal achievement.
Study NCT05113212 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Macular surgery with NGENUITY surgical display system
Description: Patient undergoes VR surgery with visualization using heads up display 3D monitor viewed by the operating surgeon
Study NCT05113212 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Macular surgery with standard operating microscope
Description: Patient undergoes VR surgery with visualization using standard operating microscope
Study NCT05312190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZhenQi BuXue KouFuYe
Description: Zhenqi Buxue Oral Liquid consists of sheep placenta, pearl, red ginseng, wolfberry, astragalus, angelica, coix seed, ginger and jujube. The excipients are protein sugar and sodium benzoate. Nourishes qi and blood. It is suitable for dizziness, pale complexion, fatigue, lack of energy and lazy words caused by insufficient qi and blood.
Study NCT05312190 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Progesterone Capsules
Description: The main ingredient of Progesterone Capsules is abbsolutely progesterone,a kind of hormone,which is the main method of western medicine for the treatment of menstrual disorders
Study NCT05312190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progesterone Capsules
Description: The main ingredient of Progesterone Capsules is abbsolutely progesterone,a kind of hormone,which is the main method of western medicine for the treatment of menstrual disorders
Study NCT05903118 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RBMRNA-176
Description: Anti-viral RNA vaccine for active immunization against COVID-19 administered as intramuscular injection
Study NCT05903118 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection
Study NCT04895202 — intervention group
Intervention type: OTHER
Intervention: Siponimod
Description: Prospective observational cohort study. There is no treatment allocation. Patients administered siponimod as by swiss label, that have started before inclusion of the patient into the study will be enrolled.
Study NCT05819983 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ivermectin Tablets
Description: Ivermectin 200µg/kg BW
Study NCT05819983 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Permethrin Cream
Description: Permethrin cream 5%
Study NCT05990075 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: self-monitoring
Description: This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
Study NCT05624229 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proton Pump Inhibitors
Description: PPI infusion continued to use for 5 days in experimental group
Study NCT05624229 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: No Proton Pump Inhibitors
Description: PPI infusion stopped in standard group after endoscopy.
Study NCT06647108 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Food Supplement
Description: The composition of the dietary supplement is the following (for 1 sachet): 450 mg glucomannan, 250 mg white mulberry dry extract (d.e.), 200 mg gymnema (d.e.), 200 mg olive (d.e.), 200 mg Cassia nomame (d.e.), 200 mg Nopal, 5 mg policosanols and 20 µg chromium
Study NCT06647108 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT06647147 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic training
Description: For twelve weeks, the women in the study group will participate in aerobic training on cycle ergometer. Each session will consist of 30-45 minutes of cycling at a moderate intensity, accompanied by a workout heart rate ranging from 65% to 75% of the maximal heart rate and ranging between 12 and 14 on the Borg rating of perceived exertion 20-point scale. After ten minutes of warm-up, every session will end with a brief 3-minute period of cool-down.
Study NCT06647147 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diaphragmatic breathing exercises
Description: From the hook-lying position, the women will receive instructions to position their hands on the rectus abdominis muscle located under the anterior chest wall. They will be advised to inhale slowly and deeply, expanding their abdomen without causing any movement in their upper chest, while simultaneously relaxing their shoulders. Slowly, the women will expel every breath. Air will be inhaled via the nose, swelling the abdomen. After the breath ceased, the women will purse her lips and exhale from his mouth with half-opened lips and a hollow belly. A single respiratory cycle consists of a three-second intake, followed by a three-second pause, and concluding with a six-second expiration phase.
Study NCT05165303 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lidocaine with propofol
Description: different concentrations of lidocaine added to propofol varying from
Study NCT05246618 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TUM012
Description: Ex-vivo infusion
Study NCT05246618 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Ex-vivo infusion
Study NCT04837235 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hemay005
Description: oral
Study NCT06647368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PET with 18-FDG
Description: The intervention is a 1,5 hour PET scan, which will be performed in three steps (heart scan, brain scan and heart scan) and administration of radioactively labelled glucose (18-FDG) in two doses.
Study NCT06209411 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Based Testing
Description: Community Health Workers (CHWs) will offer at home OGTT testing to women within the first postpartum year, as well as Type 2 Diabetes education.
Study NCT06209411 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Clinic Based Screening
Description: Community Health Workers (CHWs) will offer referral to clinic based OGTT testing to women within the first postpartum year, as well as Type 2 Diabetes education.
Study NCT05961488 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Coronary Calcium Score and Coronary CT angiogram
Description: Introduction of early Coronary CT angiogram and Coronary Calcium Score in the first days after a resuscitated out-of-hospital cardiac arrest.
Study NCT05707533 — intervention group
Intervention type: PROCEDURE
Intervention: TVM using the Vaginal Adventitia Reserved and Anatomical Implant Technique
Description: The Transvaginal mesh procedure with Vaginal Adventitia Reserved and Anatomical Implant Technique for the treatment of POP. The Cefoxitin Injection Solution was used for Prophylactic antibiotics
Study NCT06109441 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: ALTB-268
Description: ALTB-268 drug product (DP) for SC injection is supplied as a sterile and preservative-free frozen solution or lyophilized powder. All excipients used in the DP formulation are of multi-compendial quality and have precedence for use in parenteral products.
Study NCT06580509 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tranexamic Acid Injectable Product
Description: Participants will receive three doses of TXA 500 mg (5 mL of TXA 100mg/ml) nebulized using a PARI LC D Disposable Nebulizer or equivalent over 10-15 minutes using 8 or greater liter/minute of gas flow.
Study NCT06580509 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: Participants will receive three 5 ml doses of placebo (normal saline) nebulized using a PARI LC D Disposable Nebulizer or equivalent over 10-15 minutes using 8 or greater liter/minute of gas flow.
Study NCT06392659 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-993
Description: Suspension for Oral Administration.
Study NCT06392659 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemfibrozil
Description: Tablets for Oral Administration.
Study NCT06392659 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Capsules for Oral Administration.
Study NCT06392659 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Solution for Oral Administration.
Study NCT05456178 — intervention group
Intervention type: OTHER
Intervention: Electrostatic wipe
Description: The main objective will be to study the feasibility of the quantification of domestic fungal exposure with electrostatic wipe. The interval of environmental fungal exposure quantification values measured by conventional mycology and by NGS will be established, with analysis of the correlation between the quantification obtained by the two techniques.~For this, an electrostatic wipe will be deposited in the living room and another one in the bedroom for 12 weeks. The wipes will be analyzed by the mycology laboratory of the Croix Rousse hospital.
Study NCT06431282 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CO2 laser + HA
Description: Probands will be treated with a CO2 laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Study NCT06431282 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thulium laser + HA
Description: Probands will be treated with a thulium laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Study NCT05875415 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bilateral dry needling in latent trigger points of the Flexor digitorum Brevis Muscle
Description: Bilateral dry needling in latent trigger points of the Flexor digitorum Brevis Muscle in flatfoot
Study NCT05875415 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Bilateral non emission Laser in latent trigger points of the Flexor digitorum Brevis Muscle
Description: Bilateral non emission Laser in latent trigger points of the Flexor digitorum Brevis Muscle in flatfoot
Study NCT05574426 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Movement Breaks
Description: Participants will be asked to perform 30-60 second movement breaks 3-4 times per day on at least 3 days per week.
Study NCT05574426 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Movement Breaks
Description: Participants will be asked to perform 30-60 second movement breaks 3-4 times per day on at least 3 days per week.
Study NCT06500364 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LoopLoc Arm
Description: Patients in this intervention will have had a capsular closure performed using a LoopLoc device after their hip arthroscopy.
Study NCT06500364 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control Arm
Description: Patients in this intervention will have not had a capsular closure using a LoopLoc device after their hip arthroscopy.
Study NCT05021640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DCR-AUD
Description: DCR-A1203, the drug substance of DCR-AUD, is a synthetic double-stranded (hybridized duplex) RNA oligonucleotide conjugated to GalNAc ligands that enable specific hepatic access and uptake after subcutaneous administration. DCR-AUD is a sterile solution of DCR-A1203 at a concentration of 160 mg/mL in water for injection (WFI).
Study NCT05021640 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: DCR-AUD
Description: DCR-A1203, the drug substance of DCR-AUD, is a synthetic double-stranded (hybridized duplex) RNA oligonucleotide conjugated to GalNAc ligands that enable specific hepatic access and uptake after subcutaneous administration. DCR-AUD is a sterile solution of DCR-A1203 at a concentration of 160 mg/mL in water for injection (WFI).
Study NCT05021640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for DCR-AUD
Description: 0.9% saline for injection
Study NCT06015204 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Interscalene brachial plexus block targeting the C5-to-C6 nerve roots
Description: With the head rotated contralateral to interscalene brachial plexus block (ISBPB), the compactly arranged brachial plexus is visualized lateral to the pulsating subclavian artery under ultrasound guidance. The linear ultrasound transducer is moved cephalad until the C5-to-C8 nerve roots are visualized between the anterior and middle scalene muscles. A block needle is introduced from lateral to medial direction. A nerve root is blocked by placing at least 5 ml of 0.75% ropivacaine around it. The most caudal cervical nerve root (C6 nerve root) is blocked first, and the most cephalad one (C5 nerve root) is blocked last. Then, 3 ml of 0.75% ropivacaine is placed between the scalene and sternocleidomastoid muscles to block the supraclavicular nerves. An equivalent volume of a standard study drug is planned to be used (A total of 25 ml of 0.75% ropivacaine).
Study NCT06015204 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Interscalene brachial plexus block targeting the C5-to-C8 nerve roots
Description: With the head rotated contralateral to interscalene brachial plexus block (ISBPB), the compactly arranged brachial plexus is visualized lateral to the pulsating subclavian artery under ultrasound guidance. The linear ultrasound transducer is moved cephalad until the C5-to-C8 nerve roots are visualized between the anterior and middle scalene muscles. A block needle is introduced from lateral to medial direction. A nerve root is blocked by placing at least 5 ml of 0.75% ropivacaine around it. The most caudal cervical nerve root (C8 nerve root) is blocked first, and the most cephalad one (C5 nerve root) is blocked last. Then, 3 ml of 0.75% ropivacaine is placed between the scalene and sternocleidomastoid muscles to block the supraclavicular nerves. An equivalent volume of a standard study drug is planned to be used (A total of 25 ml of 0.75% ropivacaine).
Study NCT05981274 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: serum biomarker.
Description: serum biomarker:CTX-II, COMP, hsCRP, TNF-a, CTX-I, sRANKL, OPG, and Osteopontin (OPN)
Study NCT05835206 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microbiome Therapeutic
Description: Participants will receive a single course of study treatment (IP, Encapsulated Microbiota): Orally delivered, non-frozen, encapsulated investigational intestinal microbiota, consisting of 16 capsules. One dose (8 capsules) is administered daily (QD) for 2 days. The capsules are to be taken orally with water on an empty stomach. Each dose will be taken approximately every 24 hours, with a minimum of 12 hours from the previous dose to a maximum of 36 hours. Both doses must be completed within the stated 36 hours ±12 hours. Depending on the time of the first dose, dosing may occur over 3 calendar days.~A second cycle will begin and a second treatment will be given if the participant is still MDRO positive on Day 14 of Cycle 1. If applicable, Cycle 2 will begin within 7 days of Day 14.
Study NCT05835206 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive a single course of study treatment (Color-matched placebo capsules containing microcrystalline cellulose (MCC) powder), consisting of 16 capsules. One dose (8 capsules) is administered daily (QD) for 2 days. The capsules are to be taken orally with water on an empty stomach. Each dose will be taken approximately every 24 hours, with a minimum of 12 hours from the previous dose to a maximum of 36 hours. Both doses must be completed within the stated 36 hours ±12 hours. Depending on the time of the first dose, dosing may occur over 3 calendar days.~A second cycle will begin and a second treatment will be given if the participant is still MDRO positive on Day 14 of Cycle 1. If applicable, Cycle 2 will begin within 7 days of Day 14.
Study NCT04817553 — intervention group
Intervention type: OTHER
Intervention: exposure to COVID19
Description: Observational study of IgG4 patients with pancreatobiliary involvement who were diagnosed with COVID19
Study NCT06231173 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual Feedback Therapy and Conventional Therapy
Description: In experimental group individuals will receive visual feedback therapy and Conventional rehabilitation therapy. In visual feedback therapy, bilateral method is used to receive the visual feedback from the mirror. This visual feedback therapy consists of the following parts as the patient is asked to follow the involved hand that did the mimicking while the non-involved side will be performing wrist flexion, wrist extension, ulnar deviation, radial deviation, supination, pronation, and closing hand and opening hand.In conventional therapy, Patients are given a rest time of 20 seconds in each activity and a 1-minute break in each segment in order to reduce fatigue of the noninvolved hand. The treatment will be applied by the therapist standing at the side of the patient. Then technique will be applied according to subject's tolerance for duration of 15 minutes in each sitting. This treatment protocol will be 5 times/week for 4 weeks in the hospital setting.
Study NCT06231173 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Therapy
Description: In control group individuals will receive only conventional therapy. In conventional therapy, Patients are instructed to perform a sandbag and hand grip exercise with a resistive exercise for the non-involved side. At last, patients are instructed to perform a moving small object (ball of wool) and card flip operation to induce wrist and finger movements as functional activities. Patients are given a rest time of 20 seconds in each activity and a 1-minute break in each segment in order to reduce fatigue of the non involved hand. The treatment will be applied by the therapist standing at the side of the patient. Then technique will be applied according to subject's tolerance for duration of 15 minutes in each sitting. .This treatment protocol will be 5 times/week for 4 weeks in the hospital setting.
Study NCT06129773 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: antibiotic coated vicryl used for fascial closure
Description: in this group fascial closure was done with antibiotic coated vicryl to compare with non coated vicryl after lapaprotomy in contaminated wounds