AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04875897 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: keepMED PAP device
Description: The keepMED PAP device is an automatic, wearable positive airway pressure device indicated for treatment of obstructive sleep apnea. A therapeutic pressure is delivered to the patient upper airway through a nasal interface. It is similar to other marketed positive airway pressure devices with respect to its fundamental use of positive airway pressure for the treatment of sleep apnea as well as with regard to its functional components and accessories (e.g., a PAP unit, a mask/nasal interface, an air filter, tubing, etc.).
Study NCT04668703 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conbercept intravitreal injection
Description: intravitreal injection of 0.5 mg conbercept at the conclusion of cataract surgery
Study NCT05517733 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet Rich Fibrin
Description: for the preparation of PRF, A well-trained professional nurse drew 10ml of patient blood from the antecubital vein and transferred it to a test tube without anticoagulant. The blood sample was immediately centrifuged for 10-12 minutes at 3000 rpm. L-PRF was ready to use after centrifugation.~PRF membrane was put over the implant and slightly tucked under the soft tissue periphery, then held in place with a figure-of-8 suture by 0.5 proline suture
Study NCT05517733 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Diode laser
Description: * A 980 nm diode laser device (BIOLASE) was applied in a circular motion to the blood formed at the socket orifice at a power of 1W for 1 minute with a continuous wave mode, the application was done without touching the pooling blood and with a non-activated tip of the fiber optic.~* The laser application cycle was repeated 3-5 times to yield a stable fixed blood clot covering the dental implant with no oozing blood from its periphery.
Study NCT05887141 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Double Standards
Description: We created a VR intervention based on the Cognitive Behavioral Therapy (CBT) technique 'double standards'. In the intervention the participants have to respond to a virtual character they imagine as their friend, who expresses similar self-criticism as they struggle with themselves. Two role-plays are played in Virtual Reality (either with or without perspective change after the role-plays). In the perspective change condition, the perspective is changed with the virtual friend (second person perspective).
Study NCT05887141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Double Standards
Description: We created a VR intervention based on the Cognitive Behavioral Therapy (CBT) technique 'double standards'. In the intervention the participants have to respond to a virtual character they imagine as their friend, who expresses similar self-criticism as they struggle with themselves. Two role-plays are played in Virtual Reality (either with or without perspective change after the role-plays). In the perspective change condition, the perspective is changed with the virtual friend (second person perspective).
Study NCT05887141 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Self-criticism avatar
Description: We created a VR intervention called 'Self-criticism avatar' that has common ground with two-chair dialogue. Participants have to assertively respond to their inner critic who criticizes them using their own self-critical thoughts. After responding assertively (for example: 'Go away, I don't need you', 'Good is good enough'), the virtual character becomes weaker until they give up. Two role-plays are played in Virtual Reality (either with or without perspective change after the role-plays). In the perspective change condition, the perspective is changed with a bystander (third person perspective).
Study NCT05887141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-criticism avatar
Description: We created a VR intervention called 'Self-criticism avatar' that has common ground with two-chair dialogue. Participants have to assertively respond to their inner critic who criticizes them using their own self-critical thoughts. After responding assertively (for example: 'Go away, I don't need you', 'Good is good enough'), the virtual character becomes weaker until they give up. Two role-plays are played in Virtual Reality (either with or without perspective change after the role-plays). In the perspective change condition, the perspective is changed with a bystander (third person perspective).
Study NCT06428877 — intervention group
Intervention type: OTHER
Intervention: analyzed on the post-operative scanner
Description: analyzed on the post-operative scanner
Study NCT04933799 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PF-06650833
Description: PF-06650833 is an investigational, highly potent and selective, reversible inhibitor of IRAK4. IRAK4 is a serine, threonine kinase that is a key intracellular signaling node downstream of the myddosome-associated Toll-Like Receptors (TLR) 1, 2, 4, 5, 6, 7, 8, 9 and 10, and the interleukin (IL)-1 family receptors (IL-1R, IL-18R and IL-33R) that mediate much of the innate immune signaling.~As an inhibitor of TLR signaling, PF-06650833 targets a different part of the immune system from the Janus kinase (JAK) inhibitors. Given the partial redundancy of innate immune signaling through IRAK4-independent TLR pathways and the lack of direct suppression of T- and B-cell signaling, PF-06650833 is unlikely to lead to exaggerated immunosuppression.
Study NCT04933799 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo
Description: Placebo will match the study drug in dose, formulation, route and frequency.
Study NCT05018897 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: To Share or Not to Share
Description: Strategic disclosure intervention to help participants evaluate the pros and cons of disclosing suicidality and provide guidance on best way to disclose to get needs met. Six one-hour virtual sessions conducted weekly.
Study NCT05018897 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Peer Support
Description: Peer-led support group for mood disorders. Six one-hour virtual sessions conducted weekly.
Study NCT06124976 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ST-02
Description: ST-02 drug instillation into the upper urinary tract (renal pelvis)
Study NCT05333822 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bashan
Description: a vegetable plant based compound drink add after three meals for 14 days
Study NCT05333822 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: water
Description: water as placebo
Study NCT05579665 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelet-rich Plasma
Description: Research participants own blood will be used to prepare the platelet rich plasma injectate.
Study NCT05579665 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome
Description: Conditioned Medium UC-MSCs Secretome which will be injected into the affected knee using ultrasound guidance.
Study NCT05579665 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low Molecular Weight Hyaluronic Acid
Description: low molecular weight hyaluronic acid which will be injected into the affected knee using ultrasound guidance.
Study NCT05296447 — intervention group
Intervention type: OTHER
Intervention: No Intervention
Description: All subjects that previously received RGX-314 in a parent study
Study NCT04795583 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Description: Prednisone 25 mg capsules
Study NCT04795583 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Point of Care testing device for C-reactive protein
Description: Determination of C-reactive protein blood levels by point of care testing device
Study NCT04795583 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Point of Care testing device for C-reactive protein
Description: Determination of C-reactive protein blood levels by point of care testing device
Study NCT05354310 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: VOILA
Description: Participants will be given dietary supplement powder containing protein, galactooligosaccharide (GOS), vitamin D, and calcium throughout the twelve weeks of intervention. This will be accompanied with a resistance training regime whereby participants will train three times a week for the three months. A variety of measurements will be carried out at baseline and at endline.
Study NCT06204120 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LPM3480392 Injection
Description: PCA administration
Study NCT04469062 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirikizumab IV
Description: Administered IV
Study NCT04469062 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mirikizumab SC
Description: Administered SC
Study NCT04469062 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vedolizumab IV
Description: Administered IV
Study NCT04469062 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo IV
Description: Administered IV
Study NCT04469062 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo SC
Description: Administered SC
Study NCT05191836 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluation of the effectiveness of Video Game Distraction in the management of anxious pediatric patients during dental treatment
Description: The child will be provided dental treatment during watching video game.The Behavior Rating Scale HOUPT will be measured four times: directly when the patient seated comfortably on the dental chair, after anesthesia, after pulpotomy, and when the treatment completed.~All child patients will ask to choose a face that describe their status from one of the Simplified Wong Baker faces scale in the same four times.
Study NCT05191836 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Evaluation of the effectiveness of Audio Video Distraction in the management of anxious pediatric patients during dental treatment
Description: The child will be provided dental treatment during audio video distraction.The Behavior Rating Scale HOUPT will be measured four times: directly when the patient seated comfortably on the dental chair, after anesthesia, after pulpotomy, and when the treatment completed.~The child will be provided dental treatment during watching video game. All child patients will ask to choose a face that describe their status from one of the Simplified Wong Baker faces scale in the same four times.
Study NCT05191836 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Evaluation of the anxiety in pediatric patients during dental treatment without using any type of distraction aids
Description: The child will be provided dental treatment without using any type of distraction aids.The Behavior Rating Scale HOUPT will be measured four times: directly when the patient seated comfortably on the dental chair, after anesthesia, after pulpotomy, and when the treatment completed.~The child will be provided dental treatment during watching video game. All child patients will ask to choose a face that describe their status from one of the Simplified Wong Baker faces scale in the same four times.
Study NCT05060835 — intervention group
Intervention type: OTHER
Intervention: Virtual assistants offering medical recommendations to health care profesionals
Description: the project will interconnect, following a federated approach, large, distributed cancer imaging repositories, currently used for AI tools training and validation, with patient registries and EHRs of cancer-related data and supports exploitation of relevant unstructured data through novel Natural Language Processing (NLP) tools
Study NCT05043883 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CathVision Cube® system
Description: Intracardiac signals will be passively recorded using the investigational CathVision Cube® System in parallel with the commercial (bearing CE mark) EP recording systems LabSystem Pro, Boston Scientific EP, or EP-Tracer, Schwarzer Cardiotek. The investigational device will not be used for direct clinical care decisions or therapy. The validation of the PVI Analyzer will be performed offline and retrospectively.
Study NCT05364645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Given IV
Study NCT05364645 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Given IV
Study NCT05364645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Given IV
Study NCT05364645 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pemetrexed
Description: Given IV
Study NCT05364645 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selpercatinib
Description: Given PO
Study NCT05092477 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integrated Intervention for Breast Cancer Survivors with Diabetes
Description: All pilot participants will be required to have a SMB target to be included in this study. A SMB target will be chosen by the participant after reviewing their 18mo follow-up responses with the Care Coach. Participants may endorse a maladaptive belief or emotional response; however, this is not required to participate in this intervention. At each follow-up session, the Care Coach will review the participant's SMB goal and progress, address participant's challenges and suggest alternatives, and correct further misinformation on the disease(s). Additionally, the Care Coach will reinforce or introduce techniques that could help overcome barriers to reaching SMB goal and recommend participants to continue improving on the same goal or begin action planning towards a new SMB goal.~1. Just SMB concern~2. SMB + maladaptive belief + emotional response~3. SMB + maladaptive belief~4. SMB + emotional response
Study NCT05092477 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attention Control
Description: Participants in the control arm will receive a brochure to discuss healthy lifestyle behaviors to improve DM management. To control for the potentially confounding effect of personalized attention from the care coach on the relationship between the intervention and outcomes, participants also receive 4 calls to discuss study progress, thoughts and feelings about study/illness/behaviors, remind them about returning their pill bottles, and about scheduling for their upcoming 24mo follow-up study interview.
Study NCT05342519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rapamycin
Description: While rapamycin is not approved for the treatment of vitiligo, it has been found to be efficacious in stopping disease progression in animal models. Another recent study in humans showed that doses of 0.5cc daily of 0.001% of the topical formulation are able to achieve improvement in hypopigmented lesions of the skin at both the clinical and histological level. At this dose, improvement in cell function was observed regarding maintenance of proliferative potential and prevention of senescence, with avoidance of total inhibition of cell growth as has been seen at higher potencies used for immunosuppression.
Study NCT05342519 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rapamycin
Description: Rapamycin is an immunosuppressant that works by inhibiting the mammalian target of rapamycin (mTOR) leading to inhibition of the cell cycle and antibody production. It has also been shown to promote expansion of Treg populations. Although studies evaluating alternative dosing for vitiligo are limited, topical rapamycin has previously been used to treat angiofibromas related to Tuberous Sclerosis, vascular malformations such as port-wine stains, and inflammatory lesions such as plaque psoriasis. In a 2019 meta-analysis, 38 out of 40 reports included used topical formulations of 1% or lower potency rapamycin; the majority of publications were focused on the treatment of Tuberous Sclerosis, where the median concentration of mTOR inhibition was 0.1% dosed twice daily.
Study NCT05342519 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: All patients will be assigned to received topical placebo cream to the lesion not being treated with the active study drug.
Study NCT06497790 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: BJH-SDS Screenint Test
Description: The test includes the assessment of a sufficient level of consciousness (Glasgow Coma Scale over 13 points), a check for facial paresis, soft palate paresis and tongue paresis followed by a water swallow test with 90 ml of water if the previous points are assessed as normal. The water swallow test checks for signs of aspiration (throat clearing, coughing or a change in voice quality)
Study NCT06497790 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Flexible Endoscopic Evaluation of Swallowing
Description: The FEES evaluates anatomical changes, functional disorders of the visible structures (e.g. recurrent paresis), saliva management, penetration and aspiration of food boluses in order to draw conclusions about the underlying pathomechanism of dysphagia. It is an established standard diagnostic procedure for stroke patients and, in addition to the diagnosis of dysphagia, also enables pathomechanism-guided therapy by speech therapists
Study NCT06204120 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: PCA administration
Study NCT04909671 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gi Genius, Medtronic
Description: GI geniusTM (Medtronic) is an artificial intelligence device designed and validated on a dataset of white-light endoscopy videos from high-quality randomized controlled trials for the detection of colorectal lesions during colonoscopy. Based on a deep learning system using convolutional neural networks, GI genius works in real-time side-to-side with the gastroenterologist during colonoscopy highlighting the presence of precancerous lesions with a visual marker (green box) in real time and designed to be integrated with the majority of colonoscopies.
Study NCT04909671 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: White light standart colonoscopy
Description: High definition white light endoscopy will be used during the scope withdrawal
Study NCT06208878 — intervention group
Intervention type: OTHER
Intervention: Non Interventional
Description: Safety and Efficacy Assessment
Study NCT06467214 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CONNECTED
Description: CONNECTED is a manualized, peer-led, group-based social isolation intervention for diverse veteran populations in VA primary care settings. It is delivered via videoconference through individual and group sessions over 8 weeks.
Study NCT06467214 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: VET BEFRIENDING
Description: VET BEFRIENDING (attention control arm) consists of weekly social interactions with a research assistant (RA) over videoconference or phone.
Study NCT05479747 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: post operative analgesics
Description: post-operative pain killer
Study NCT05479747 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: post operative analgesics
Description: post-operative pain killer
Study NCT05479747 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: post operative analgesics
Description: post-operative pain killer
Study NCT05157737 — intervention group
Intervention type: OTHER
Intervention: Electrophysiological detection of KCNQ2 mutation
Description: Electrophysiological detection of KCNQ2 mutation performed using patch clamp technique in an in vitro cell model. Analyze the association between phenotype and genotype.
Study NCT05157737 — intervention group
Intervention type: OTHER
Intervention: Multi-modal brain image and EEG
Description: Multi-modal brain image include brain magnetic resonance imaging (MRI) or positron emission tomography-computed tomography (PET-CT). The electroencephalogram (EEG) incuding video electroencephalogram (VEEG) and sleep electroencephalogram (SEEG).
Study NCT05157737 — intervention group
Intervention type: OTHER
Intervention: Omics testing
Description: Omics testing include proteomics, metabolomics, transcriptomics.
Study NCT06204120 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: morphine hydrochloride injection
Description: PCA administration
Study NCT06220409 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dance classes
Description: A 12-week dance class training program two times a week for 3 months
Study NCT05480397 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TENS, Distractive techniques, cryotherapy
Description: Group (1): Will receive (TENS , cryotherapy and conventional physical therapy ) Massage with ice was done by the researcher over the AVF puncture site . After that, the TENS electrodes will be applied by the researcher 6 centimeters apart closely up and down the skin area for insertion of the needle.~* Group (2): Will receive (Distraction techniques ,cryotherapy and conventional physical therapy ) Initially five minutes before starting hemodialysis, Distraction techniques will be applied. Natural and eye-catching images were broadcasted through a video display device on a laptop monitor in a manner that was easy for the older patient to watch while they were lying on the bed. Massage with ice was done by the researcher over the AVF puncture site~* Group (3): Will receive (cryotherapy and conventional physical therapy )
Study NCT05015556 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimal invasive volar plating
Description: Muscle sparing osteosynthesis, no casting postoperatively
Study NCT06544876 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: sit-to-stand
Description: test for balance during movement from sitting to standing
Study NCT06544876 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sit-to-stand
Description: test for balance during movement from sitting to standing
Study NCT06544876 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: stand to sit
Description: test for balance during movement from standing to sitting