AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06766279 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Treatment
Description: The OMT intervention in this study will be comprised of an occipitoatlantal (OA) decompression and treatment of the nasal Chapman point. The OA decompression will be applied for 2 minutes with 12N of pressure as this pressure has been determined to produce the greatest effect. Treatment at this level reduces congestion of nasal mucosa. The suboccipital decompression technique is generally considered to bear minimal risks and is perceived by most patients as a pleasant experience. This technique is considered to be a basic skill among osteopathic physicians. It is usually taught within the first semester of the first year at Colleges of Osteopathic Medicine.~The other intervention technique will be addressing the nasal Chapman points that are found at the tip of the transverse process of C1 and the costochondral junction of the first rib on each side. Both techniques are performed while the subject is supine.
Study NCT06766279 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham treatment
Description: The sham intervention will consist of the subject lying supine with the investigator's hands resting gently on both sides of subject's neck for 5 minutes.
Study NCT06766942 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: structured sherborne developmental movement program with sensory integration program
Description: In addition to the sensory integration therapy they receive at the rehabilitation center for 45 minutes, two days a week for 12 weeks, the Structured Sherborne Developmental Movement Program will be applied.
Study NCT05303766 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intra-articular steroids
Description: Intra-articular steroids for Knee osteoarthritis
Study NCT06766942 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sensory integration program group
Description: Sensory integration therapy programmed according to the individual's needs and disabilities will be applied to this group by an occupational therapist at the rehabilitation center for 45 minutes, 2 days a week for 12 weeks.
Study NCT06766942 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: control group
Description: This group will not participate in any activities outside of the standard special education program.
Study NCT06769178 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Virtual Reality based
Description: Participants will receive treatment by a specialist physiotherapist for a total of 16 sessions, 2 days a week on non-consecutive days for 8 weeks. Both groups will receive neurodevelopmental treatment (NGT) for 16 sessions. While the control group will receive traditional balance training in each session, the VR group will play virtual reality-based games.
Study NCT06769178 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality based
Description: Participants will receive treatment by a specialist physiotherapist for a total of 16 sessions, 2 days a week on non-consecutive days for 8 weeks. Both groups will receive neurodevelopmental treatment (NGT) for 16 sessions. While the control group will receive traditional balance training in each session, the VR group will play virtual reality-based games.
Study NCT06769789 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Drug free invitro activation Ovary
Description: Drug free invitro activation Ovary
Study NCT06768489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JNJ-79635322
Description: JNJ-79635322 will be administered subcutaneously.
Study NCT06768489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab will be administered subcutaneously.
Study NCT06768489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: Pomalidomide will be administered orally.
Study NCT06769919 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Neoadjuvant radiotherapy
Description: The experimental group will receive neoadjuvant systemic therapy combined with neoadjuvant radiotherapy before undergoing surgery
Study NCT06768359 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual acupuncture and standard therapy
Description: Manual acupuncture is acupuncture needle insertion was done perpendicularly to the acupuncture points GV20, EXHN3, HT7, and PC6 using Huanqiu needle measuring 0.25 x 25mm with mild stimulation rotation technique at a speed of 60x/minute and needle retention for 30 minutes. Therapy was performed every day for 6 days.~Standard therapy is anxiolytic drugs and supportive psychotherapy given to patients according to the decision of the psychiatrist treating the patient.
Study NCT06768359 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture and standard therapy
Description: Sham acupuncture is when acupuncture needles are inserted into acupuncture points, but do not actually penetrate the skin, only attached to the plaster. Therapy was performed every day for 6 days.~Standard therapy is anxiolytic drugs and supportive psychotherapy given to patients according to the decision of the psychiatrist treating the patient.
Study NCT05303766 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed Radio-frequency
Description: Intraarticular Pulsed Radiofrequency of the knee
Study NCT05999617 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation
Description: Conventional rehabilitation (stretching, strengthening, balance) and dual task exercise training (simple math during active stretching, carrying the ball without dropping child while on the balance pad) will be applied 3 days a week for 12 weeks. Interventions will be implemented individually. Patients will be evaluated before and 12 weeks after the interventions.
Study NCT05999617 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Conventional rehabilitation (stretching, strengthening, balance) and dual task exercise training (simple math during active stretching, carrying the ball without dropping child while on the balance pad) will be applied 3 days a week for 12 weeks. Interventions will be implemented individually. Patients will be evaluated before and 12 weeks after the interventions.
Study NCT05730036 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Linvoseltamab
Description: REGN5458 will be administered by intravenous (IV) infusion
Study NCT05730036 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elotuzumab
Description: Elotuzumab will be administered by IV infusion
Study NCT05730036 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pomalidomide
Description: Pomalidomide capsules will administered by mouth (PO)
Study NCT05730036 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone
Description: Dexamethasone tablets/capsules will be administered PO and/or by IV infusion
Study NCT05668819 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TH-001
Description: TH001 is a software program intended to treat adults with prediabetes.
Study NCT05947279 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Comparing motor adaptation reaching performance
Description: By comparing motor adaptation reaching performance between these three groups, the investigators can examine how stimulation to each specific area of the brain modulates different aspects of motor adaptation
Study NCT05947279 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Comparing motor adaptation reaching performance
Description: By comparing motor adaptation reaching performance between these three groups, the investigators can examine how stimulation to each specific area of the brain modulates different aspects of motor adaptation
Study NCT05160246 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesiology tape
Description: The tape will be fixed without any tension 10 cm below the origin of the rectus femoris muscle. Then 35-50% tension will be applied to the band and descended to the patella. After this point, the Y-shaped band will be terminated to wrap the patella medially and laterally without any tension.
Study NCT05160246 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tape
Description: The tape will attach to the rectus femoris without any tension.
Study NCT06330246 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low oxalate fixed diets pre-colonization
Description: 4 days of fixed eucaloric diet with low oxalate (\< 60 mg/day), normal calcium (600-1000 mg/day)
Study NCT06330246 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moderately high oxalate fixed diets pre-colonization
Description: 4 days of fixed eucaloric diet with moderately high oxalate (250-300 mg/day), normal calcium (600-1000 mg/day)
Study NCT06330246 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Colonization with Oxalobacter formigenes
Description: Ingestion of live Oxalobacter formigenes
Study NCT06330246 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Low oxalate fixed diets post-colonization
Description: 4 days of fixed eucaloric diet with low oxalate (\< 60 mg/day), normal calcium (600-1000 mg/day)
Study NCT06330246 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Moderately high oxalate fixed diets post-colonization
Description: 4 days of fixed eucaloric diet with moderately high oxalate (250-300 mg/day), normal calcium (600-1000 mg/day)
Study NCT05617300 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Dementia Caregiving
Description: Mindfulness Based Stress Reduction (MBSR) is a standardized program that is both psychoeducation and skills-based, which uses mindfulness meditation practices to help people better cope with their emotions. This study uses a version of MBSR designed specifically for care partners of people living with dementia (PLWD) called Mindfulness Based Dementia Caregiving. Mindfulness Based Dementia Caregiving (MBDC) is a program with 8 weekly 2 hour sessions (plus one extended practice 4 hour retreat) including both formal and informal mindfulness practices, role play, and lectures combined with some dementia-specific education. Participants learn how to incorporate mindfulness practices into day-to-day life to help cope with the challenges and stresses of dementia care.
Study NCT04613141 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: WalkingTall-PD
Description: Smart garment (socks, insoles or ankle bands) delivering rhythmic haptic stimuli to the ankle timed with preferred cadence. Smart phone application delivers auditory cues synchronised with haptic stimuli. Smart phone application delivers a neurorehabilitation program.
Study NCT04613141 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Mobility-plus
Description: Active 'pseudo placebo' comparator using a paper-based body weight exercise program.
Study NCT05332093 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: skin biopsy
Description: 4mm skin biopsy
Study NCT05332093 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: venous blood sample (plasma, PBMC, WB)
Description: venous blood sample to acquire plasma, PBMCs and whole blood
Study NCT05332093 — intervention group
Intervention type: GENETIC
Intervention: venous blood sample (HLA)
Description: venous blood sample used for HLA typing
Study NCT05332093 — intervention group
Intervention type: GENETIC
Intervention: skin slit
Description: genome sequencing of parasite DNA that is extracted from the skin slit
Study NCT05640843 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole Foods Plant-based Diet
Description: The meals will have a low glycemic index and contain vegetables, whole grains, and plant-based fats that have undergone minimal processing. Detailed recommendations for snacks and breakfasts meeting the standard of a WFPBD will also be given to supplement their daily calorie needs with access to education materials. Patients will also receive dietary education and counselling from a research dietitian every 4 weeks for the 12-week intervention period. They will have access to the team for questions and support as needed
Study NCT05640843 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Algae omega 3
Description: Algae omega 3 given twice daily.
Study NCT05640843 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplements
Description: Placebo supplements given twice daily.
Study NCT06344572 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SAT-001
Description: Device: SAT-001(a Software as Medical Device) Using SAT-001 application for 48 weeks and wearing single vision spectacles
Study NCT06344572 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Single vision spectacles
Description: Wearing single vision spectacles
Study NCT06524076 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Partial Pulpotomy
Description: After removing caries high-speed handpiece with water coolant using a round diamond bur. Once there is an exposure, the bur is changed with another sterile one with which the superficially inflamed pulp tissue will be gently removed to a depth of 1-3 mm beneath the pinpoint pulp exposure that occurred at the end of caries removal. A sterile cotton pellet with saline will be placed with light pressure for 2-3 minutes to achieve hemostasis.
Study NCT06524076 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Complete pulpotomy
Description: After removing caries with a large round bur, the access cavity will be opened. Excavation of inflamed coronal pulp tissues will be done using a sharp excavator. A sterile cotton pellet with saline will be placed with light pressure for 2-3 minutes to achieve hemostasis.
Study NCT04163887 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: hepatectomy
Description: Resection colorectal liver metastases using a laparoscopic approach or an open approach.
Study NCT06279637 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Joint Home-DM-BAT Intervention
Description: 8 weekly sessions of telephone-delivered, manualized education on diabetes management, problem solving of social needs, and behavioral activation.
Study NCT06279637 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Diabetes education materials will be mailed weekly and monthly according to the booster schedule
Study NCT05607732 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MyCog
Description: MyCog uses well-validated, self-administered, iPad-based measures from the NIH Toolbox for the Assessment of Neurological Behavior and Function Cognition Battery to provide an efficient and sensitive cognitive screen that can be easily implemented in primary care. Preliminary data shows these tests can discriminate between cognitively normal older adults and those with CI (specifically mild cognitive impairment); enabling physicians to assess CI in ways currently not available.
Study NCT05453877 — intervention group
Intervention type: OTHER
Intervention: No intervention will be applied.
Description: This is an observational study.
Study NCT06063122 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: smallTalk NICU Active
Description: The novel smallTalk NICU Active product design allows a disposable pacifier (equipped with the smallTalk sensor) to act as an infant-controlled mechanism for administration of developmentally appropriate parental voice, delivered by the NICU-safe speaker contingent upon the infant suck strength meeting an individually calibrated threshold.
Study NCT06063122 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: smallTalk NICU Active
Description: The novel smallTalk NICU Active product design allows a disposable pacifier (equipped with the smallTalk sensor) to act as an infant-controlled mechanism for administration of developmentally appropriate parental voice, delivered by the NICU-safe speaker contingent upon the infant suck strength meeting an individually calibrated threshold.
Study NCT05235620 — intervention group
Intervention type: OTHER
Intervention: PatientToc use in pharmacies
Description: PatientToc has been adapted for use in pharmacies. Patients using specific medications will be prompted to complete questionnaires about their self-reported adherence.
Study NCT05153460 — intervention group
Intervention type: DEVICE
Intervention: Telemetry and manual monitoring vs Contactless monitoring devices
Description: All participants will be on standard telemetry monitoring for Heart Rate, Respiration Rate and movements using the gold standard (Electrocardiography and Capnography respectively).~In addition, two contactless monitoring devices will be placed on the patient bed to measure data simultaneously. These devices include EarlySense (USFDA approved ballistocardiography device) and Dozee VS (Investigational Device).
Study NCT05963737 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PS setting strategy in pressure-support ventilated patients
Description: Use PMI guide PS setting in pressure-supported ventilated patients and keep PMI within the target range (0-2cmH2O).
Study NCT06215001 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mechanical ventilation setting (Positive end-expiratory pressure) according to Expiratory Flow Limitation
Description: Positive End expiratory pressure will be set according to the positive end-expiratory pressure able to revert the expiratory flow limitation.
Study NCT06215001 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical ventilation setting (Positive end-expiratory pressure) not according to Expiratory Flow Limitation
Description: Positive End expiratory pressure will be set not according to the positive end-expiratory pressure able to revert the expiratory flow limitation but to a standard level of 4 cmH2O.
Study NCT06190912 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bryostatin 1
Description: Eligible participants will be treated with bryostatin over a 26-week period. Doses 1, 2, 8, and 9 of the study drug will be a loading dose 20% higher (i.e., 24 µg) than the assigned fixed dose and will be administered one week apart. Otherwise, the assigned fixed dose is 20 µg. Drug is administered intravenously (IV) by continuous infusion over 45(±5) minutes. Participants are scheduled to receive 14 doses over 26 weeks.
Study NCT05689476 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NAVA GROUP
Description: NAVA ventilation: Assisted Ventilation Mode, synchronized, through EAdi catheter, with patient's inspiratory effort and proportional to respiratory drive
Study NCT05807711 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: L-Methyl Folate and methylcobalamine
Description: Dietary supplement labeled to contain methylfolate 800 micrograms and methylcobalamine 1000 micrograms
Study NCT06621368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: the RT program will consist of eight exercises for different body segments, namely: vertical bench press, horizontal leg press, low row, leg extension, scott curl, leg curl, triceps pulley and seated calf raise. Every 12 weeks of training, the program will be restructured with changes in the order in which the exercises are performed, the number of sets, the number of repetitions or the training system in an attempt to avoid a supposed adaptive plateau. The protocols in each stage will follow the recommendations for prescribing RT for the elderly, aiming at improving strength and hypertrophy, namely: a combination of single-joint and multi-joint exercises (free weights and machines), slow or moderate execution speed (ratio 1:2 for concentric and eccentric muscle actions, respectively), one to three sets of multiple repetitions, 8-12 RM or 10-15 RM, with recovery intervals between sets of one to two minutes, and a training frequency of two to three weekly sessions, on alternate days.
Study NCT06621368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control-no treatment
Description: Participants will maintain their daily activities.
Study NCT05986578 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TMS to dmPFC
Description: TMS will be delivered with a MagVenture Mag Pro R30 with the Cool-B70 A/P coil with active liquid cooling and active/sham sides. For dmPFC, approximately 25% of the nasion-inion distance or Talairah coordinates X 0 Y+60 Z+60 will be measured. The first session will begin with the acquisition of the resting motor threshold (rMT) on the contralateral hand. iTBS (triplet 50 Hz bursts, repeated at 5 Hz, 2 sec on and 8 sec off; 600 pulses per session) will be delivered at 110% of the rMT and will last \~3 minutes. The stimulation will start at a lower percentage and ramp up over time to acclimate participant to the feeling of stimulation. The intensity will be lowered in participant cannot tolerate the stimulation. Each participant will receive 3 sessions per visit with a 15-20 minute interval between sessions to increase the likelihood of detecting acute effects.
Study NCT05986578 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TMS to dlPFC
Description: TMS will be delivered with a MagVenture Mag Pro R30 with the Cool-B70 A/P coil with active liquid cooling and active/sham sides. For dlPFC, position F3 will be measured, using probabilistic EEG placement. The first session will begin with the acquisition of the resting motor threshold on the contralateral hand. iTBS (triplet 50 Hz bursts, repeated at 5 Hz, 2 sec on and 8 sec off; 600 pulses per session) will be delivered at 110% of the rMT and will last 3 minutes. The stimulation will start at a lower percentage and ramp up over time to acclimate participant to the feeling of stimulation. The intensity will be lowered in participant cannot tolerate the stimulation. Each participant will receive 3 sessions per visit with a 15-20 minute interval between sessions to increase the likelihood of detecting acute effects.