AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06390670 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo treatment
Description: In the control procedure each athlete was supplemented with a chronic dose of 25 g/day of placebo (PLA). PLA was particularly prepared for the study, and was an isoenergetic/isomacronutrient product (high quality protein) prepared for the trial (Agrapak, Poland). The PLA was provided in the powder form and were taken twice a day (12.5 g in the morning and 12.5 g in the afternoon). Participants were instructed to dissolved each portion of the PLA preparation in 250 mL of plain water.
Study NCT05830747 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pre-operative Placebo administration before third molar surgery
Study NCT04470895 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Failure Track patients analysis
Description: The nurse coordinator of the Fracture Track first comes to give the patient a written information note. She answers the patient's questions and obtains his or her non-opposition. The patient must be given sufficient time for reflection to make his decision in order to participate in the study. His non opposition will be traced in the computerized medical record. Each enrolling patient in the study can simultaneously participate in another research. There is no exclusion period in the protocol.~Once the patient is included, a semi-directed interview is conducted. The name of the patient's usual pharmacy will be collected. Data from the computerised medical record concerning the patient's stay are also analysed.~The patient's usual pharmacy or the nurse in charge of the patient will then be questioned in order to carry out a drug reconciliation interview.
Study NCT04996056 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TNX-1300
Description: TNX 1300 200 mg Intravenous injection
Study NCT05254301 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention group
Description: This personalised multimodal treatment considers evidence- and practice-based elements (e.g., self-management, individual guidance \& follow-up, low-threshold activities, homebased functional training \& better follow-up guidance afterwards).
Study NCT04996056 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: Usual Care per the Emergency Department protocol for Cocaine Intoxication
Study NCT05372809 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SkinTE
Description: SkinTE is an Autologous Heterogeneous Skin Construct (AHSC), which is manufactured from a small piece of healthy full-thickness skin harvested from the patient at the time of randomization to the SkinTE arm. SkinTE is manufactured aseptically by PolarityTE following current Good Manufacturing Practice (cGMP). SkinTE is not cultured ex vivo; rather, it is returned to the provider expeditiously to maintain cellular viability. SkinTE includes various multicellular segments as a result of the manufacturing process. The different multicellular segments contain different types of skin cells, such as keratinocytes, dermal fibroblasts, dermal endothelial cells, and follicular cells, as well as extracellular matrix. The multicellular segments have a surface area-to-volume ratio for improved sustenance by imbibition prior to engraftment.
Study NCT05372809 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Standard care is defined in this protocol to include the following:~* Debridement~* Collagen-alginate primary wound dressing~* Local offloading with felt pad for wounds on weight bearing surfaces~* Foam~* Multi-layer compression dressing~* Off-loading device such as a full-length boot or total contact cast (if full-length boot cannot accommodate the patient) or surgical shoe for ulcers in non-weight bearing locations
Study NCT06417632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graded Zirconia Crown
Description: monolithic implant supported crown
Study NCT06417632 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Zirconia Crown
Description: monolithic implant supported crown
Study NCT05987644 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alectinib
Description: 600mg taken orally, twice daily for 25 Cycles Cycle = 4 weeks (28 days)
Study NCT05987644 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Radiosurgery
Description: SRS dose varies by brain met size and location
Study NCT04547257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Seraph 100
Description: Bloodfiltration with Seraph 100
Study NCT05254301 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intervention group
Description: This personalised multimodal treatment considers evidence- and practice-based elements (e.g., self-management, individual guidance \& follow-up, low-threshold activities, homebased functional training \& better follow-up guidance afterwards).
Study NCT04404335 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Crevicular fluid analysis by using ELISA testing.
Description: Samples of crevicular fluid (fluid existing in the space between the gums and the roots of the teeth) will be obtained from healthy and periodontal patients. In periodontal patients, samples will be taken before and after receiving a routine course of periodontal treatment (root scale and polish) to assess the levels of a peptide called LL-37 and inflammatory cytokines (IL-4, IL-6, IL-10): Samples will then be analysed using laboratory procedures (ELISA)
Study NCT05408689 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: T1 TENS
Description: The subjects in Group A will received TENS (Burst mode, 9 pulses per burst, pulse frequency =160Hz, burst frequency=2Hz, intensity was set to trigger visible muscular twitches). Two 2 x 3 cm electrodes was attached on T1 level with 2 cm from the spine. Previous study has shown that it was effective to improve the cognitive function in subjects with Alzheimer's disease.
Study NCT05408689 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Concha TENS
Description: The subjects in Group B will received TENS (25Hz, 0.5mA) on the concha of left outer ear. The electrical stimulation was generated by the portable neurostimulator (Nemos®, Cerbomed, Erlangen, Germany) and was delivered by a titanium electrodes positioning on top of a silicon earplug. Previous study has shown that it was effective to improve the Accelerate extinction memory formation and retention in healthy young adults.
Study NCT05408689 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: The subjects in Group C will receive 30 min sham electrical stimulation on T1 by a placebo-TENS device. The Placebo-TENS was applied by an apparently identical TENS unit. The unit's power indicator light was illuminated, but the unit's electrical circuit had been manually disconnected inside. In order to shape the common mindset, all subjects (except those in the Control group) were informed that they might or might not feel an electrical current, as different stimulation parameters were being applied.
Study NCT04964869 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: epinephrine solution injection
Description: epinephrine solution injection at least 1 ml to the post- sphincterotomy wound
Study NCT06174168 — intervention group
Intervention type: OTHER
Intervention: Modified Frailty Index -11
Description: MFI-11: the parameter included in the score is history of congestive heart failure, presence of diabetes mellitus, history of chronic obstructive pulmonary disease or pneumonia, functional health status/dependence, history of hypertension, history of myocardial infarction, cardiac problems, cognitive impairment, history of transient ischemic attack or cerebrovascular accident, history of peripheral vascular disease is questioned. Patients will be monitored according to standard non-operating room anesthesia procedures.
Study NCT06470880 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adaptive Therapy
Description: A blood test that measures the amount of tumour DNA circulating in the patient's blood (known as ctDNA) will be conducted every two weeks to check if the cancer cells are still present, and if they are becoming active. The result of this test will allow doctors to monitor the activity of the tumour and judge when to pause and resume encorafenib and binimetinib treatment. This intermittent treatment is called 'adaptive therapy'.
Study NCT06470880 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Encorafenib and binimetinib delivered to UK standard of care.
Study NCT05591781 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high frequency chest wall oscillation with vest system
Description: Patients were assigned to 2 groups with pre- and post- treatment protocol application. All patients were thoroughly evaluated before and after treatment protocol application.
Study NCT05591781 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Lung flute (OPEP)
Description: . Thirty patients (Group B) received Lung flute (OPEP) in addition to their prescribed medication, 3 times per week twice a day for three successive weeks
Study NCT06250387 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endobronchial ultrasound transbronchial cryobiopsy
Description: Endobronchial Ultrasound (EBUS) :~EBUS is usually performed under general anesthesia using a laryngeal masque. It has a linear ultrasonography with a 7.5 MHz frequency. The distal part of the endoscope contains a water filled balloon used as a liquid interface, camera, light source and a working channel. The needle is protected by a sheath to prevent working channel damage. The endoscope is connected to a processor that reflects both endobronchial and ultrasound images on a screen.~EBUS - TBNA : EBUS - Transbronchial needle aspiration EBUS - TBCB: EBUS - Transbronchial Cryo Biopsy
Study NCT05384730 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group nutrition and exercise support
Description: Weekly group nutrition and exercise support delivered online through trained volunteers
Study NCT04693143 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: A randomized controlled open-label clinical trial.
Description: This was a single-center; open-label randomized controlled trial performed at a Pediatric Intensive Care Unit (PICU) in tertiary care hospital
Study NCT06114524 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: binaural music
Description: In the binaural music group, an MP3 player and in-ear stereo headphones were provided. Music therapy was applied for 15 min before the procedure.
Study NCT05939778 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TH-SC01(Umbilical cord mesenchymal stem cells)
Description: 5+7 principle:~1. In medium and high dose groups, 5 subjects were included in each dose group in the first step, and the first 3 subjects had good safety The investigator evaluated safety and efficacy data and could enroll a fourth and fifth subject.~1. If the number of successful participants in these 5 subjects is less than 2, the study in this dose group will be ended due to drug ineffectiveness, and the researcher will evaluate the safety and enter the next dose group.~2. If the number of successful participants in these 5 cases is greater than or equal to 2, then proceed to the second step.~2. 7 subjects were included in the second step.
Study NCT05196711 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MAX-40070
Description: In the SAD phase, the proposed doses will be increased gradually. Each cohort will consist of 8 subjects, with 6 subjects randomly assigned to MAX-40070.~During the MAD phase, the treatment will be administered once a day for 14 consecutive days.
Study NCT05196711 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: In the SAD phase, the proposed doses will be increased gradually. Each cohort will consist of 8 subjects, with 2 subjects randomly assigned to placebo~In the MAD phase, the treatment will be administered once a day for 14 consecutive days. Each cohort will consist of 10 subjects, with 2 subjects randomly assigned to placebo
Study NCT05725759 — intervention group
Intervention type: BEHAVIORAL
Intervention: Rehabilitation
Description: Particapants currently receiving tofersen treatment will be referred to outpatient physical and/or occupational therapy.
Study NCT05731921 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The exercise program with the 'Empathy Dress'
Description: The experimental group will be given an exercise program that includes a total of eight sessions (two months) of 'Empathy Dress' and some exercises (stairs going up and down, sitting up, putting on trousers, tying shoes, etc.), every week and 20 minutes per week, by the researchers.
Study NCT05981066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoantigen vaccine, I.M injection
Description: Patients will receive a fixed applicable dose of ABOR2014(IPM511) administered.
Study NCT04783688 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Full Face Snorkel Mask (FFSM)
Description: A mask used for snorkeling that covers the entire face, as opposed to a conventional snorkel, which is held in the mouth only.
Study NCT04722055 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multigene Methylation Detection Kit
Description: Eligible participants are required to take stool samples for multigene methylation detection and gene sequencing, undergo colonoscopy examination, and have a biopsy when necessary (gold standard).
Study NCT06435559 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neurotablet® and Neuropsychological evaluations
Description: The experimental group will carry out cognitive rehabilitation using the Neurotablet device. The cognitive rehabilitation will be performed for 10 consecutive weeks, once a week for 1 hour. Neuropsychological evaluations will be conducted before the start of chemotherapy (T0), 6 months (T1) and 12 months (T2) after the start of chemotherapy. Neuropsychological evaluations will include tests to analyze the main cognitive domains of memory, attention, executive functions and learning.
Study NCT06435559 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Neuropsychological evaluations
Description: Neuropsychological evaluations will be conducted before the start of chemotherapy (T0), 6 months (T1) and 12 months (T2) after the start of chemotherapy. Neuropsychological evaluations will include tests to analyze the main cognitive domains of memory, attention, executive functions and learning.
Study NCT04598399 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based Relapse Prevention
Description: 7 x 60-120 minute sessions with different themes: Automatic pilot/triggers/relapse/high-risk situations/ mindfulness in daily life. There will be a welcoming time, with a focus on at-home practice and difficulties, a theoretical presentation of new concepts, practical meditation exercises and a debriefing.
Study NCT04598399 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Relaxation/ meditation
Description: 7 x 60-120 minute sessions each with a different sound from nature with unguided, closed relaxation group with a maximum of 12 participants
Study NCT04850781 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bi-weekly frozen meal home delivery
Description: All participants randomized to this arm will receive 10 frozen meals that are mailed to their home every two weeks from a MOW vendor, TRIO foods.
Study NCT04850781 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Daily home meal delivery
Description: All participants randomized to this arm will receive meals delivered to their home multiple times per week from a MOW program employee/volunteer with a wellness check and socialization.
Study NCT06286176 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Videos with breastfeeding education material and encouraging messages
Description: Distributed videos aim to increase breastfeeding related knowledge and to receive support
Study NCT06286176 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Whatsapp group
Description: The Whatsapp group is used in the intervention as a platform for interpersonal exchange of information and experience, in addition to peer support.
Study NCT05677672 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Human TH-SC01 Cell Injection
Description: Single injection of 0.6×10\^7,1.2×10\^8, 1.8×10\^8 cells/kg
Study NCT05677672 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline solution
Description: saline solution will be given at the same quantity and following the same schedule
Study NCT05713669 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Encounter visit with Patients
Description: Participants in this encounter group will be asked to complete a pre and post-intervention survey, participate in a meeting with a former ICU patient at a post-ICU clinic, and undergo an in-person interview within fourteen days following the encounter.
Study NCT05699148 — intervention group
Intervention type: DRUG
Intervention: Elexacaftor / Ivacaftor / Tezacaftor
Description: Triple combination therapy is licensed in the UK for prescription to paediatric patients aged 6 to 11 years. ETI will be started as part of routine clinical care.
Study NCT04794140 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: different number of passes
Description: Each patient's operation process is the same, that is, after obtaining enough specimens for diagnosis by endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) wet suction technique, additional three passes are performed. One of which is randomly selected as the one pass group, and the other two passes automatically as the two pass group. Please refer to the literature for EUS-FNB wet technique (Tong T, et al. J Gastroenterol Hepatol. 2020;10.1111/jgh.15371.)
Study NCT04125680 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: ESL Health Literacy Classes
Description: The intervention will last 8-weeks, and the first and last classes will be devoted to survey assessments. Participants will be asked to reflect on their health knowledge and behaviors, and how they have changed since starting the program. The curriculum administered during the classes will use pedagogies for health literacy as a practice. It will focus on skills needed to learn about lead exposure in the ESL classroom: (1) vocabulary; (2) grammar; and (3) identifying risk factors, symptoms and preventive strategies. A focus on health literacy as practice will include personal engagement using language in context: (1) role-play interactions about lead exposure prevention; (2) discussing views about risk, and how to talk about it with peers and family members; (3) identifying sources of reliable health information; and (4) learning to ask for support and resources.
Study NCT06005454 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Fish oil (Omega)
Description: We will use a dietary supplement source of omega 3 fatty acids from the available syrup ( each 5 ml contain 640 mg of high DHA Fish oil) so we will give it in a dose 2.7 ml twice daily for children between 1 and 3 years and 3.5 ml twice daily for children between 4 and 5 years.
Study NCT05464017 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Optimized version of the mHealth screening tool (intervention) using the machine learning approach
Description: An improvement to the mHealth triage tool using a machine learning approach, optimizing the efficiency of call schedule and the prediction of which patients are most likely to benefit from follow-up care given data collected at the hospital through the Cameroon Trauma Registry, as well as post-discharge phone contact attempts and survey information. The backbone of the estimators is the ensemble machine learning algorithm the Superlearner, which has been applied to medical contexts, including injury and trauma. It is a theory-driven method based on cross-validation, which combines potentially many different learners (e.g., standard regression, tree regression, random forest, neural nets) such that the model chosen (a weighted average of the learners) is asymptotically equivalent to the so called Oracle - the learner that fits optimally for the data-generating distribution. Note, double-robust CV-TMLE versions of this estimator are available as the tmle3mopttx function in tlverse.
Study NCT04681092 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AKS-452
Description: s.c. or i.m. vaccination
Study NCT05713669 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Non-encounter surveys
Description: Surveys will be completed pre and post patient follow-up.
Study NCT05301374 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Watching Cartoon
Description: Children in the cartoon group before the procedure, they chose one of the cartoons predetermined by the researchers. The children in the cartoon group started watching a cartoon of their choice 2 minutes before the procedure and they kept watching until the procedure was ended.
Study NCT05604183 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non-invasive hyperspectral retinoscopy
Description: The Principal Investigator or a trained medical nurse (under the supervision of the principal investigator) will take an image of the retina of the patient with the Mantis Photonics hyperspectral retinoscopy camera.
Study NCT05604183 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: blood sample
Description: The Principle Investigator or a trained medical nurse (under the supervision of the Principal Investigator) will draw a small blood sample according to the standard medical procedures for drawing blood samples.
Study NCT05759884 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-VEGF
Description: Intravitreous injection of anti-VEGF drugs
Study NCT05759884 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anti-VEGF
Description: Intravitreous injection of anti-VEGF drugs
Study NCT05759884 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: subthreshold micropulse laser
Description: 577nm micropulse laser photocoagulation therapy
Study NCT05397236 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacaine- Magnesium
Description: Patients received QL block with 20 ml of 0.25% bupivacaine (2, 4)plus 5 ml of 10% MgSO4.