AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01490671 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1% tenofovir gel
Description: One applicator of 1% tenofovir gel will be inserted by the participant into the vagina once each day for 28 days or until delivery, whichever comes first
Study NCT01490671 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gel
Description: One applicator of placebo gel will be inserted by the participant into the vagina once each day for 28 days or until delivery, whichever comes first
Study NCT04980885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK117
Description: Subjects receive AK117 intravenously.
Study NCT04980885 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Subjects receive Azacitidine subcutaneously.
Study NCT05420883 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acupressure
Description: One minute after the Nonstress test recording starts, sequential pressure will be applied to the Zhi yin (BL67) acupuncture points simultaneously for 2 minutes. The process will be repeated a second time, with a three-minute rest period. After the 20-minute Nonstress test procedure, the test will be evaluated by the researcher and her anxiety will be determined.
Study NCT05420883 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Halojen ışık
Description: One minute after the start of the Nonstress test recording, halogen light stimulation will be given from the mother's abdomen over the fetal head for 10 seconds and the procedure will be repeated after 10 minutes. After the 20-minute Nonstress test procedure, the test will be evaluated by the researcher and her anxiety will be determined.
Study NCT05420883 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: No application will be made to the control group. After the 20-minute Nonstress test procedure, the test will be evaluated by the researcher and her anxiety will be determined.
Study NCT04762953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Intraperitoneal Paclitaxel
Study NCT04762953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: IV Paclitaxel
Study NCT04762953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin
Description: IV Leucovorin
Study NCT04762953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: IV 5-FU
Study NCT05432778 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letermovir Pill
Description: Patients in the Study Group will receive virostatic prophylaxis with letermovir 480 mg qd (We will be utilizing Letermovir oral formulation of 240 mg or 480 mg as available). n all patients the virostatic prophylaxis will be initiated between days 4 and 7 after heart transplantation and the duration of virostatic prophylaxis will be determined by the Quantiferon-CMV assay.
Study NCT05474599 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional physical therapy
Description: TENS
Study NCT05474599 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Dry cupping therapy
Description: Experimental group was given Dry cupping therapy along with TENS.
Study NCT04698369 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vibration Massage Therapy
Description: WearUL is a patent pending wearable rehabilitation technology that targets localized vibration massage therapy directly onto the body. The frequency and amplitude combinations to be delivered by WearUL are safe and effective in clinical and research settings based on previous studies on focal vibration.
Study NCT04335240 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Premature family music therapy intervention to support parenting, attachment bond and preterm development
Description: We have structured an integrated psychological and music therapeutic protocol that aims to limit or overcome neonatal long-term developmental morbidities, promote parenting and attachment bond in preterm infants.
Study NCT06258915 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adalimumab
Description: Adalimumab (80mg at day 0, then 40mg/14 days from W1 to W35 subcutaneously)
Study NCT06258915 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mycophenolate Mofetil
Description: 2 g/day orally for 36 weeks
Study NCT05259254 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mobile Application
Description: the mobile application will be consist of 4 modules which are: video observed therapy, health education, reminder system, and feedback.
Study NCT05259254 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Direct Observed Therapy
Description: it is a specific strategy that require identification, training, and supervision by various parties such as healthcare worker, community volunteer, or family members to directly monitor the ingestion of anti-TB medication. DOT was aimed to improve medication adherence by active monitoring and documenting the consumption of each dose taken. Conducting DOT is not only limited to directly observe the treatment, but also can assess medication side effects as well as to document the visit and information regarding medications (e.g., frequency and timing of taking medication).
Study NCT04502628 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hyperbaric oxygen therapy
Description: Patients with hemorrhagic cystitis (HC) after allo-HSCT will receive hyperbaric oxygen therapy (HBOT) on the next day of the HC diagnosis was determined. Then HBOT will be scheduled every day until symptoms of HC vanished. Other classic measures to treatment HC such as hydration, alkalization, and bladder irrigation will also be carried out at the same time.
Study NCT04038593 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Youtube© relaxation music
Description: Use of non standardized relaxation music with Youtube© during cares
Study NCT04038593 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MUSIC CARE© intervention
Description: Use of MUSIC CARE© during cares
Study NCT05052866 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Robot
Description: Participants will interact with a social robot companionbot for a period of 8-10 weeks. The robot will stay in participants' apartments.
Study NCT06409780 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Comparative analysis of CUS, CAD and CXR in pulmonary TB
Description: The strumental analysis of pulmonary TB signs with chest ultrasound, chest x-ray and CAD will be compared in two different settings: index cases and household contacts
Study NCT06148974 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Polar lipid 1
Description: 15g plant polar lipids from plant source 1. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).
Study NCT06148974 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Polar lipid 2
Description: 15g plant polar lipids from plant source 2. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).
Study NCT06148974 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Non-polar lipids
Description: 15g non-polar plant lipids from plant source 1. The lipids supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).
Study NCT06148974 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: No lipids
Description: A commercial white wheat flour bread as a source of available carbohydrates (50 g), without added lipids.
Study NCT05998356 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Balloon Eustachian Tuboplasty (BET) under general anesthesia.
Description: Subjects will undergo general anesthesia with intubation. After retraction of the inferior turbinate using Naphazoline, the balloon will be inserted under optical control through the pharyngeal ostium of the Eustachian tube and inflated two times at a pressure of 10 bars as instructed by the manufacturer.
Study NCT05998356 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Insertion of catheter for probing and flushing the Eustachian tube under general anesthesia
Description: Participants in the control group will benefit from the insertion of a dedicated catheter, TubaClean, into the Eustachian tube during 2 minutes with gentle washing with saline solution, and then the catheter will be removed. This type of device is used to wash the Eustachian tube lumina during ear surgery. Thus, the procedure in the control group will be very close to the BET, except that no dilation will be performed. No Eustachian tube dilation will occur in this control group since the diameter of the catheter itself is not large enough to cause dilation. Eustachian tube catheterization is not per se a treatment of ETD but just of mucosal plugs, and the investigators expect no effect of this catheter insertion on the outcomes of the study. At the end of the procedure, subjects will have nasal dressings similar to the BET procedure to ensure the blinding of the study.
Study NCT05484245 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sonography
Description: Surgeon detects brain mass lesion and assesses extent of it's resection with sonography
Study NCT05741151 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PET-Neck Parkinsonian patients
Description: Brain and neck PET-CT scan with 68Ga-PSMA to detect metabolism in the Superior Cervical Ganglion of both sides.
Study NCT04774770 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HED-Start
Description: The HED-Start Program is a cognitive-behavioral intervention based on self-management and motivational interviewing principles.
Study NCT06071273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group A: online real-time home based exercise using the online platform
Description: Patients that will be randomly assigned to this group will be exercising at home by providing data of their vital signs during exercise and at rest. To succeed this, they will be provided with the appropriate equipment (e.g., a smart watch able to assess the electrical signs of the heart (i.e., ECG) and heart rate, an automated blood pressure monitor, and an electrical body scale) which will be directly linked to the online platform.~The online real-time supervised home-based exercise program is identical to Group B, the only difference is that it is performed at home. Each session has a duration of 60 minutes consisting of 40 mins of aerobic exercise and 20mins of resistance training. The overall intensity is kept to moderate based on ratings of perceived exertion (i.e., 13-14 in Borg's scale 6-20). The program will last for 6 months with exercise sessions taking place thrice per week.
Study NCT06071273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group B: supervised community based exercise intervention
Description: Identical exercise program to Group A, the only difference is that Group performs the supervised exercise in community based health clubs/gyms.
Study NCT06391502 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-component Exercise Intervention Program
Description: The Vivifrail program (http://vivifrail.com) is a home-based exercise program that focuses on personalized multi-component exercise prescriptions based on an elderly person's functional abilities, including resistance/strength, balance, flexibility, and cardiovascular endurance exercise (i.e., walking).~During hospitalization, patients who meet the criteria of sodium intake will be screened, and then divided into groups according to the method of randomized controlled trial. The experimental group will carry out corresponding exercise plan according to the results of SPPB.
Study NCT06328426 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D
Description: The dose of Vitamin D will be 1000 IU /day taken orally. The duration of the intervention will be 4 months.
Study NCT06328426 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Omega-3
Description: The dose of omega-3 will be 1000 mg /day taken orally. The duration of the intervention will be 4 months.
Study NCT06328426 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: The dose of metformin will be 1000 IU /day taken orally. The duration of the intervention will be 4 months.
Study NCT06328426 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The duration of the intervention will be 4 months.
Study NCT05239351 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jalucomplex
Description: Device: Jalucomplex Jalucomplex is an injectable intradermal gel containing sodium salts derived from hyaluronic acid.
Study NCT05857631 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Image guided External Beam Radiation Therapy (EBRT)
Description: External beam radiotherapy to pelvis:~Post operative hypofractionated external beam radiotherapy with intensity modulated/arc technique, to a dose of 39 Gy in 13 fractions, at 3 Gy per fraction, delivered once daily, 5 days a week, over 2.5-3 weeks.
Study NCT05857631 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Patients who require adjuvant chemotherapy along with radiation, based on predefined risk features, will receive 5 cycles of cisplatin on a weekly basis with a dose of 40 mg/m2 by IV infusion over a period of 1 hour 2-4 hours prior to start of EBRT.
Study NCT05857631 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Vaginal brachytherapy
Description: Vaginal brachytherapy, two fractions of 6 Gy each, delivered 1 week apart.
Study NCT05166460 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kidney cooling device
Description: renal cooling device designed to maintain renal hypothermia at or below 5ºC for 60 minutes.
Study NCT05937139 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breastfeeding education
Description: Breastfeeding education will be given to fathers.
Study NCT05793918 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Percutaneous Electrolysis an neuromodulation
Description: Therapeutic Percutaneous Electrolysis an neuromodulation associated with eccentric exercises devices at home.
Study NCT05793918 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional group
Description: Ultrasound pulsatil therapy (US), transcutaneous electric nerve stimulation (TENS) for 20 minutes and associated with eccentric exercises devices at home.
Study NCT05139290 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prototype Intervention
Description: The prototype intervention will be likely family-based and focused on issues of communication, problem-solving, health system literacy, and family systems, all considered in the context of the African-American (AA) adult daughter role and cultural identity.
Study NCT05057923 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bacillus subtilis
Description: Bacillus subtilis, a harmless intestinal commensal, has earned in recent years, great reputation as a vaccine production host and delivery vector with advantages such as low cost, safe for human consumption and straightforward administration. The technology team has succeeded engineering Bacillus subtilis with spore coat proteins resembling the proteins of the nucleus and spikes of coronal virus. This product could have a vaccine like activity within the intestinal environment.
Study NCT04782843 — intervention group
Intervention type: OTHER
Intervention: HEP score assessement
Description: Assessement of the HEP score between 2 physician.
Study NCT05722132 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: One cycle
Description: Message Design Participants will receive 3 messages per cycle that contain information on how to enroll in a cessation program.
Study NCT05722132 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 4 cycles
Description: Participants will receive 3 messages per cycle that contain information on how to enroll in a cessation program.
Study NCT05722132 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 5 Dollar Incentive
Description: Participants will receive 3 messages per cycle that contain information on how to enroll in a cessation program. The introductory message will mention that participants will receive $5 if they enroll in the program or that they should look out for messages with a $ sign at the beginning that will provide an incentive if they respond.
Study NCT05722132 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Raffle Incentive
Description: The incentive message (indicated with a leading $ sign) will invite participants to respond, and participants that do so will be included in a random drawing depending on the condition. The incentive message for the opportunity to win will contain a link to a website that provides full details of the timing of the drawing, the chances of winning, and when notification of winners will be made.
Study NCT06032936 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BBP-398
Description: BBP-398 (formerly known as IACS-15509) is a potent, selective, orally active allosteric inhibitor of SHP2, a tyrosine phosphatase that plays a key role in the RTK -MAPK signal transduction pathway. Key components of the MAPK pathway include the small GTPase RAS, the serine/threonine-protein kinase RAF, mitogen-activated protein kinase (MEK) and ERK. In cells, SHP2 binds to phosphorylated tyrosine residues in the intracellular domain of RTKs such as the EGFR, leading to activation of the downstream MAPK signaling pathway.
Study NCT06032936 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: osimertinib
Description: Osimertinib is a mutant-selective, third-generation EGFR inhibitor that targets both EGFR-activating mutations (e.g., exon 19 deletion and L858R) and EGFR-dependent on-target resistance mutation toward the 1st generation EGFR inhibitor (i.e., T790M). It is currently a first-line therapy for EGFR-mutant (EGFRmut) NSCLC, with average progression-free survival of approximately 19 months in previously untreated subjects.
Study NCT06401460 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yannianjiuzhuan method combined with reverse breathing training
Description: Timing of Operations~1. Reverse Abdominal Breathing: Performed from 9:00 AM to 11:00 AM and from 7:00 PM to 9:00 PM daily, one inhalation and one exhalation constituting one cycle, with 30 cycles per training session, twice a day, over a period of ten days.~2. Yannian Jiuzhuan Method: Conducted daily from 7:00 AM to 9:00 AM and from 9:00 PM to 11:00 PM, twice a day, for a duration of ten days.
Study NCT04987723 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Holter monitoring
Description: Assessment of HRV shall be performed in all enrolled patients. Ventricular HRV will be derived from a continuous 24-hour period of a 48-hour ambulatory Holter recording during AF. Participants will be requested to avoid alcohol and caffeine from 24-hours prior to fitting and any activity more strenuous than walking for the recording duration. After initial fitting, a 20-minute high-resolution ECG recording will be performed lying supine at rest.
Study NCT04987723 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: stress echocardiography
Description: Echocardiography will be performed using a GE Vivid 9 echocardiography machine (Vingmed-General Electric, Horten, Norway) equipped with a phased-array 3.5 MHz transducer. All measurements will be made according to the guidelines set by the British Society of Echocardiography.
Study NCT04987723 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cardiac MRI
Description: Contraindications to MRI will be excluded using the appropriate departmental screening forms. A trained scanner operator or radiographer will co-ordinate and supervise the scan. Cardiac MRI will be performed at 1.5T (Aera, Siemens Healthineers, Erlangen, Germany) with a protocol consisting of cine imaging, stress and rest perfusion, and late gadolinium enhancement (LGE).
Study NCT04987723 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Patient questionnaires
Description: Two validated Health Related Quality of Life (HRQoL) surveys designed for patients with AF will be used; the AF Effect on Quality of Life (AFEQT) and Barts AF Patient reported objective measure (PROM).
Study NCT06389253 — intervention group
Intervention type: OTHER
Intervention: Histological Analysis
Description: For the study, a minimal part of the periarticular tissue, specifically the sinus tarsi juxta-articular fatty tissue, that is normally dissected and discarded during the surgical operation of insertion and removal of the calcaneo-stop screw, will be analyzed
Study NCT05199974 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Midline abdominal closure
Description: Abdominal Closure in Emergency Midline Laparotomy
Study NCT05050253 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Super-oxidized solution (SOS)
Description: Peritoneal lavage with super-oxidized solution in patients undergoing emergency abdominal surgery for secondary peritonitis.
Study NCT05050253 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ringer's solution
Description: Peritoneal lavage with Ringer's solution in patients undergoing emergency abdominal surgery for secondary peritonitis.
Study NCT05997888 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: At-Home Strength Training Intervention
Description: A six-week strength training intervention in which participants will choose workouts to complete on their own. These workouts are 20-25 minutes light-intensity strength training with light strength bands. Exercises will have multiple options to account for various levels of ability. Additionally, there will be a group counseling session once per week via Zoom and a group strength training program.
Study NCT04207866 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Teleconferencing
Description: Use of video/audio stream to provide auditory training at a remote site.