AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05627141 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Photobiomodulation; Cryotherapy, Massage
Description: Photobiomodulation: the 20 participants will receive active photobiomodulation or sham immediately after the muscle damage and fatigue induction protocol in a randomized and crossover manner, with an interval of 15 days between each evaluation session. Cryotherapy combined with compression: the 20 participants will receive effective cryotherapy (10-12°C for 20 min) combined with high compression, or sham (25°C for 20 min) combined with light compression, on the lower limbs, immediately after the protocol. induction of muscle damage and fatigue. Effective cryotherapy or sham will be applied in a randomized and crossover manner, with an interval of 15 days between each evaluation session.~Massage: the 20 participants will receive the effective massage or sham immediately after the muscle damage and fatigue induction protocol in a randomized and crossover manner, with an interval of 15 days between each evaluation session.
Study NCT05962879 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resilience Training for Teens
Description: A brief 6-session group-based behavioral intervention for high school aged teenagers at risk of a mental illness.
Study NCT05339802 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: 9MW1411 injection 1 combined with Linezolid
Description: After randomization, 9MW1411 injection, single dose, intravenous infusion, linezolid: 600mg, given intravenously or orally every 12 hours, for a total course of treatment not exceeding 14 days.
Study NCT05339802 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: 9MW1411 injection 2 combined with Linezolid
Description: After randomization, 9MW1411 injection, single dose, intravenous infusion, linezolid: 600mg, given intravenously or orally every 12 hours, for a total course of treatment not exceeding 14 days.
Study NCT05339802 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: 9MW1411 injection placebo combined with Linezolid
Description: After randomization, 9MW1411 injection placebo, single dose, intravenous infusion, linezolid: 600mg, given intravenously or orally every 12 hours, for a total course of treatment not exceeding 14 days.
Study NCT05554809 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Strecthing
Description: Comparing the crossover-effect of dynamic versus static stretching
Study NCT05554809 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strecthing
Description: Comparing the crossover-effect of dynamic versus static stretching
Study NCT05494567 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tadalafil 5mg
Description: patients with BPH/OAB will be treated with combination therapy of tadalafil plus solifenacin for 12 weeks in group 1
Study NCT05494567 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tamsulosin Hcl 0.4 mg
Description: patients with BPH/OAB will be treated with combination therapy of tamsulosin plus solifenacin for 12 weeks in group 2
Study NCT05494567 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: solifenacin 10 mg
Description: patients with BPH/OAB will be treated with combination therapy of tadalafil plus solifenacin in group 1 and tamsulosin plus solifenacin in group 2 for 12 weeks
Study NCT04784598 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Insoles adapted in flip-flop sandals
Description: participants of both groups individually received a pair of customized flip-flop sandals, with or without foot pieces, covered with smooth synthetic leather
Study NCT04784598 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Insoles adapted in flip-flop sandals
Description: participants of both groups individually received a pair of customized flip-flop sandals, with or without foot pieces, covered with smooth synthetic leather
Study NCT06011122 — intervention group
Intervention type: PROCEDURE
Intervention: Distal radius fracture ORIF with a specific volar plate
Description: Patients who had a distal radius fracture were treated surgically : an ORIF was realised with a volar plate
Study NCT05983874 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BG505 SOSIP.664 gp140 Vaccine, Adjuvanted (3M-052 AF plus alum) Dosage
Description: 100µg Month 0 and Month 3
Study NCT05020925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1701
Description: Intravenous (IV) on Day 1 of each cycle
Study NCT05020925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib
Description: Famitinib, po, qd
Study NCT06334991 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD19 t-haNK
Description: CD19t-haNK erived from the parental NK-92 (aNK) cell line, CD19 t-haNK is a human, allogeneic, NK cell line that has been engineered to express a CAR targeting CD19. Similar to the haNK cell line, CD19 t haNK has also been engineered to produce endoplasmic reticulum-retained IL 2 and the high-affinity (158V) variant of the Fcγ receptor (FcγRIIIa/CD16a), and thereby has enhanced CD16-targeted ADCC capabilities. CD19 t-haNK is similar to PD L1 t-haNK, differing only in the CAR that is expressed (CD19 vs PD-L1).~Rituximab is a genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody directed against the CD20 antigen. Rituximab has an approximate molecular weight of 145 kD and has a binding affinity for the CD20 antigen of approximately 8.0 nM.
Study NCT05819034 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Scoliosis-Specific Exercise Program
Description: Adolescents in the control group will receive a scoliosis-specific exercise program which will be prescribed to control the progression of the scoliotic curve. This exercise program will include frontal plane active or passive correction exercises for scoliotic posture. The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.~The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.
Study NCT05819034 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scoliosis-Specific Exercise Program
Description: Adolescents in the control group will receive a scoliosis-specific exercise program which will be prescribed to control the progression of the scoliotic curve. This exercise program will include frontal plane active or passive correction exercises for scoliotic posture. The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.~The exercise program for every participant will be three sessions per week for 12 successive weeks. Every treatment session was applied for one hour.
Study NCT05819034 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Soft orthoses with external strapping.
Description: Adolescents in the experimental group will receive a scoliosis-specific exercises program which will be prescribed to control the progression of the scoliotic curve in addition to wearing the soft orthoses with external strapping. The wearing schedule of the soft orthosis with the external strapping for every participant in this group will be 12 hours daily for 12 successive weeks.
Study NCT04537299 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fisetin
Description: \~20 mg/kg/day oral, NG or D tube course for 2 consecutive days twice (Days 0 \& 1 and Days 8 \& 9)
Study NCT04537299 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo looks exactly like the treatment drug, but it contains no active ingredient
Study NCT04714268 — intervention group
Intervention type: PROCEDURE
Intervention: Aorto-iliac endovascular procedure
Description: Percutaneous procedure with stent placement
Study NCT06252025 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Memo-gration
Description: This study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items.
Study NCT06252025 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Picture reminiscence therapy
Description: Picture reminiscence therapy
Study NCT06486480 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Using robot assisted endoscopy to clear intraventricular hemorrhage
Description: More advanced surgical auxiliary instruments are used to improve surgical accuracy
Study NCT06486480 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Using robot assisted endoscopy to clear intraventricular hemorrhage
Description: More advanced surgical auxiliary instruments are used to improve surgical accuracy
Study NCT05552781 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: H002 capsule
Description: Small molecule, Capsule
Study NCT05802160 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Good Start Matters - Parenting intervention
Description: The Good Start Matters - Parenting intervention is a 2-month mobile-Health (mHealth) parenting program that aims to improve parenting practices and child health behaviors among British Columbian families of preschoolers. This intervention uses a familial approach and blends the best practices and evidence to promote positive parenting regarding 3 main areas: nutrition, physical activity, and screen-time; which altogether aim to support the development of healthy habits among young children. The mHealth app releases new material on a weekly basis and participants' engagement with the app takes about 30 minutes per week.
Study NCT05548062 — intervention group
Intervention type: OTHER
Intervention: Hydroxyurea
Description: Prospective observational study. There is no treatment allocation. Patients prescribed with Hydroxyurea are eligible to enroll into this study.
Study NCT05548062 — intervention group
Intervention type: OTHER
Intervention: Ruxolitinib
Description: Prospective observational study. There is no treatment allocation. Patients prescribed with Ruxolitinib are eligible to enroll into this study.
Study NCT06517719 — intervention group
Intervention type: OTHER
Intervention: lutetium (177Lu) vipivotide tetraxetan
Description: This is an observational study. There is no treatment allocation. The decision to initiate lutetium vipivotide tetraxetan will be based solely on clinical judgement.
Study NCT04714047 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive Resistance Training and no booster sessions
Description: An initial 12-week exercise intervention, consisting of 1-hour group sessions of progressive resistance training supervised by a physiotherapist 2 times per week.~The sessions consist of a 10-minute submaximal warm up on an exercise bike followed by 50 minutes of PRT with exercises targeting the muscles of the hip and knee joints; leg press, hip extension, hip abduction, hip flexion and knee extension. The progression will be in line with guidelines provided by the American College of Sports Medicine. The intensity will follow repetition maximum (RM) targets, from 12 RM for the first week towards 8 RM for the last weeks.~After the 12 weeks, this group consists of patients who are randomized to receive no further treatment. For the following 9 months, these patients are given a membership to a fitness center where they are encouraged to continue the same exercise regime.
Study NCT04714047 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Progressive Resistance Training and booster sessions
Description: An initial 12-week exercise intervention, consisting of 1-hour group sessions of progressive resistance training supervised by a physiotherapist 2 times per week.~The sessions consist of a 10-minute submaximal warm up on an exercise bike followed by 50 minutes of PRT with exercises targeting the muscles of the hip and knee joints; leg press, hip extension, hip abduction, hip flexion and knee extension. The progression will be in line with guidelines provided by the American College of Sports Medicine. The intensity will follow repetition maximum (RM) targets, from 12 RM for the first week towards 8 RM for the last weeks.~After the 12 weeks, this group consists of patients who are randomized to receive 4 booster sessions (at 1, 3, 5 and 7 months after termination of the initial 12 week intervention). Additionally, for the following 9 months, these patients are given a membership to a fitness center where they are encouraged to continue the same exercise regime without supervision.
Study NCT04714047 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Neuromuscular exercise and no booster sessions
Description: An initial 12-week exercise intervention, consisting of 1-hour group sessions of progressive resistance training supervised by a physiotherapist 2 times per week.~The sessions consist of a 10-minute submaximal warm up on an exercise bike followed by 50 minutes of NEMEX training with exercises focused on stability, postural function, postural orientation, lower extremity muscle strength, and functional exercises. Progression is made when an exercise is performed with good sensorimotor control and good quality of the performance and with minimal exertion and adequate control of the movement.~After the 12 weeks, this group consists of patients who are randomized to receive no further treatment. For the following 9 months, these patients are given equipment and encouraged to continue the same exercise regime at home without supervision.
Study NCT04714047 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromuscular exercise and booster sessions
Description: An initial 12-week exercise intervention, consisting of 1-hour group sessions of progressive resistance training supervised by a physiotherapist 2 times per week.~The sessions consist of a 10-minute submaximal warm up on an exercise bike followed by 50 minutes of NEMEX training with exercises focused on stability, postural function, postural orientation, lower extremity muscle strength, and functional exercises. Progression is made when an exercise is performed with good sensorimotor control and good quality of the performance and with minimal exertion and adequate control of the movement.~After the 12 weeks, this group consists of patients who are randomized to receive 4 booster sessions (at 1, 3, 5 and 7 months after termination of the initial 12 week intervention). Additionally, for the following 9 months, these patients are given equipment and encouraged to continue the same exercise regime at home.
Study NCT05091385 — intervention group
Intervention type: BIOLOGICAL
Intervention: Mepolizumab given SC 100mg every 4 weeks between Dec 2017 and Dec 2019
Description: Mepolizumab administered within the frame of a severe asthma treatment program financed by National Health Fund in Poland for patients fulfilling specific criteria of asthma severity.
Study NCT05094713 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Flossing experimental group
Description: Flossing of the tight muscles with medium wrapping pressure, which is individualized in based on the tight circumference of the participant.
Study NCT05094713 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Low wrapping pressure
Description: Control group where flossing wrapping pressure is between 20 and 30 mmHg
Study NCT05717036 — intervention group
Intervention type: DEVICE
Intervention: Serum Total Protein Measurement with TS Meter-DSP and Refractix DSP
Description: The two blood samples will be centrifuged and hematocrit measured per the plasma center's standard operating procedures. One participant sample will be dispensed onto the cleared TS Meter-DSP for a serum total protein measurement. This measurement will be used, along with other pre-screening information, to determine if the participant can donate plasma. The second participant sample will be dispensed onto the investigational Refractix DSP for a serum total protein measurement. It will be compared to the sample measurement taken on the cleared TS Meter-DSP.
Study NCT06679816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hormone replacement therapy
Description: Perioperative Hydrocortisone Reduction Therapy
Study NCT06679816 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Perioperative placebo Reduction Therapy
Study NCT04810416 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Texting- 10 minutes
Description: Participants will practice texting for 10 minutes using smart phone.
Study NCT04810416 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Writing- 10 minutes
Description: Participants will practice writing on notebook for 10 minutes.
Study NCT04810416 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Texting- 15 minutes
Description: Participants will practice texting for 15 minutes using smart phone.
Study NCT04810416 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Writing- 15 minutes
Description: Participants will practice writing on notebook for 15 minutes.
Study NCT03996109 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aim2Be smartphone app system
Description: Youth-parent dyads will receive the LiGHT program (addressing healthy eating, physical activity, screen time and sleep) via the Aim2Be smartphone app for 6 months. It provides personalization beginning with creation of an avatar and identifying user motivations, offers progressive goal-setting considering readiness, sub-tasks, milestones, self-monitoring tools with feedback and positive reinforcement. It applies behaviour change techniques, provides a knowledge centre, simulation narratives to enable decision making, and separate social exchange platforms for parents and youth to share ideas and challenges with peers. A Virtual Coach has been programmed using motivational interviewing theory. Gamification includes elements of choice, challenge, uncertainty, discovery, and kudos for achieving outcomes in the process of developing motivations, skills and mastery.
Study NCT03996109 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: BnLt smartphone app
Description: Youth-parent dyads will receive a simple app called BnLt for 6 months. It provides web-links to external websites that provide information and tips on healthy eating and activity, including the Canada Food Guide, Canadian Society of Exercise Physiology recommendations for physical activity, screen time and sleep for youth, and other resources.
Study NCT05799781 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MPC closed-loop system
Description: The Model Predictive Control (MPC) insulin infusion algorithm contains a model within the controller that takes as an input the aerobic metabolic expenditure in addition to the CGM and meal in puts. The algorithm uses heart rate and accelerometer data collected on the patient's body to calculate metabolic expenditure (METs). The METs then acts on the model for the insulin dynamics, whereby more energy expenditure and longer duration exercise can lead to a more substantial effect of insulin on the CGM. The MPC also has missed meal insulin bolus detection where the system will calculate the amount of insulin that was missed for a meal. The missed meal boluses can be delivered automatically without any input from the user. This feature can also be disabled.
Study NCT05799781 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: t:slim X2 pump with Dexcom G6 CGM and Control IQ
Description: The t:slim pump is a hybrid closed-loop system available to consumers for automated insulin delivery. Control IQ technology automatically adjusts insulin levels based on continuous glucose monitoring (CGM) readings from Dexcom G6.
Study NCT06423066 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pleural ultrasound
Description: Patients who examine pleural ultrasound preoperatively.
Study NCT05898919 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture is a technique that inserts a needle into the acupuncture point to treat a condition. In this trial, we will use acupuncture to treat postoperative urinary retention.
Study NCT05898919 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Sham acupuncture
Description: Participants will receive sham acupuncture at sham points.
Study NCT05898919 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neostigmine Injectable Product
Description: Neostigmine was injected once after postoperative urinary retention.
Study NCT05097326 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mifepristone
Description: Mifepristone 200mg taken orally
Study NCT05097326 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Misoprostol
Description: Misoprostol 50 mcg taken orally, and may receive additional doses of misoprostol 50 - 100 mcg as needed
Study NCT04364568 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: IRM Sequences T1, T2, FLAIR, T2\*, Cerebral Blood Flow (CBF) et mean diffusivity (MD)
Study NCT06311942 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC plus PD-1 inhibitors plus lenvatinib
Description: Patients in the triple adjuvant therapy group received one cycle of HAIC about a month after liver resection, HAIC was adopted the FOFOLX6 program (Folinic acid+5-fluorouracil+Oxaliplatin). The first cycle of PD-1 monoclonal antibody was administrated 2-4 weeks postoperatively, 200 mg IV, every 21 days for a total of 9 cycles. Lenvatinib was initiated orally 2-4 weeks postoperatively for 6 months.
Study NCT06311942 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: PD-1 inhibitors plus lenvatinib
Description: The first cycle of PD-1 monoclonal antibody was administrated 2-4 weeks postoperatively, 200 mg IV, every 21 days for a total of 9 cycles. Lenvatinib was initiated orally 2-4 weeks postoperatively for 6 months.