AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06138041 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Same volume of normal saline in bolus and continuous infusion as lidocaine group.
Study NCT04949269 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famotidine
Description: Specified dose on specified days
Study NCT06304688 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Yoga and Mediterranean Diet intervention
Description: It will last 12 weeks with a frequency of 2 sessions per week and each lasting 50 minutes.~* Warm-up phase (10 minutes): Conscious and gentle breathing. Gentle movements of the neck, shoulders, arms and legs to increase blood circulation and flexibility.~* Training phase (30 minutes): Series of gentle postures adapted to the needs of older adults. Includes standing, sitting and lying postures for relaxation and stretching. It will begin with basic postures and breathing techniques and will gradually advance as participants gain confidence.~* Return to calm (10 minutes): Deep relaxation in a lying position to integrate the benefits of the practice and promote total relaxation of the body and mind.~The Mediterranean diet consisted of: i) carbohydrates constitute 50% of the daily intake; ii) fats represented 35%; and iii) proteins represented 15%.
Study NCT06086106 — intervention group
Intervention type: PROCEDURE
Intervention: Dorsal Penile Nerve Block DPNB
Description: DPNB is A type of pain control post-operative, often performed as a circumferential infiltration of the root of the penis (ring block). Two skin wheals are raised at the dorsal base of the penis, one on each side just below and medial to the pubic spine. A 25-gauge, 37.5-mm needle is introduced on each side, and the bupivacaine (1 to 1.5 mL) maximum dose 2 ml concentration 0.25% for infants is injected superficially and deep along the lower border of the pubic ramus to anesthetize the dorsal nerve. For a complete ring of infiltration,
Study NCT06086106 — intervention group
Intervention type: DRUG
Intervention: Systemic opioids
Description: Systemic opioids belong to a class of analgesics, they act by attaching to opioid receptors in the brain and spinal cord. For relief of pain, they are frequently utilized in a variety of surgical procedures and can be given intravenously, and in intramuscular injections. Although opioids are considered highly effective in pain control, they can lead to several adverse effects, such as nausea, vertigo, and respiratory depression, some of which can be dangerous.
Study NCT04734717 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Neurology test
Description: movement examination of patients with covid19 disease
Study NCT04662359 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Ultrasound Assessment
Description: Patients will undergo an ultrasound scan to assess the severity of their rheumatoid arthritis.
Study NCT06408571 — intervention group
Intervention type: OTHER
Intervention: etiology
Description: As an important part of systems biology, metabolomics mainly detects various metabolites in the sample. Different from nucleic acids, proteins and other biological macromolecules, the relative molecular weight of these metabolites is small, generally within 1000Da, such as amino acids, carboxylic acids, carbohydrates, alcohols, amines, lipids and other special substances. Through qualitative and quantitative analysis of all endogenous low molecular weight metabolites before and after pathophysiology or gene modification stimulation, metabolomics reveals the essential characteristics of life activities and metabolism of the body, and provides guidance for exploring the pathogenesis, early diagnosis, treatment and prognosis of diseases.
Study NCT05960981 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online-delivered Group-based Parent Mediated Intervention for Young Children with ASD
Description: The program consists of eight weekly 2-hour group sessions, with each group consisting of 8 to 10 families. During the sessions, supervisors present the strategies to the parents and explain how to integrate them into their interactions with their children. Sample videos are shown to illustrate the strategies, and group discussions allow parents to discuss their application. In the second half of each session, the parents' recorded videos are watched, and supervisors provide feedback on whether the strategies were accurately implemented. At the end of each session, supervisors address any questions the parents may have.
Study NCT06261593 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blood flow restriction
Description: The intervention protocol through blood flow restriction in patients with hemophilic arthropathy will consist of performing two exercises: heel elevation and ankle dorsiflexion in a closed kinetic chain. Both exercises will be performed for 5-10 minutes, performing 4 series (30, 15, 15, 15 repetitions) with 30 seconds of rest between series
Study NCT06211309 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: co.mouthwas
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Study NCT06211309 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Kin
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Study NCT06211309 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Distilled water
Description: 15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min
Study NCT06578078 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Zirconium Cyclosilicate
Description: Use of sodium zirconium cyclosilicate to optimize RAASi therapy, through up-titration of ACEi, ARB, ARNI or MRA therapy according to clinical guidelines
Study NCT06578078 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care treatment (RAASi therapy)
Description: Standard of care treatment (RAASi therapy) without use of sodium zirconium cyclosilicate
Study NCT04298398 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Based-Cognitive Therapy (MBCT)
Description: MBCT is a program developed by Zindel Segal, Mark Williams and John Teasdale. During MBCT patients learn to decenter their negative thoughts and feelings, allowing the mind to move from an automatic thought pattern to conscious emotional processing. Mindfulness practices included in this program are breath awareness, body scan, sitting and walking meditation, and mindful yoga. The intervention will have the following structure: 8 weekly face-to-face meetings of 2 hours in a group format, daily home-based practice of learned skills, 4 hours of retreat/intensive group work after the fifth week, 6 months of home practice, 4 monthly consolidation face-to-face sessions.
Study NCT04298398 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emotion Focused Therapy Group for Cancer Recovery (EFT-CR)
Description: EFT-CR is an evidence-based approach to psychotherapy, which combines aspects of person-centered, gestalt and existential therapies with contemporary emotion theory and dialectical constructivism (Elliott et al, 2004, Rice \& Greenberg, 1984). On EFT-CR, therapist follows the client experience and guides the process, proposing therapeutic tasks when specific client behaviors occur. EFT-CR uses a set of emotion change principles which guide a process of emotional deepening process, from undifferentiated distress to secondary reactive emotions to primary maladaptive emotions to core pain and thence to primary adaptive emotions and emotional transformation (Elliott \& Greenberg 2016). The intervention will have the following structure: 8 weekly face-to-face meetings of 2 hours in a group format, daily home-based practice of learned skills, 4 hours of retreat/intensive group work after the fifth week, 6 months of home practice, 4 monthly consolidation face-to-face sessions.
Study NCT04298398 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as usual (no intervention)
Description: Treatment as Usual is the condition in which participants will follow the usual institutional intervention protocol for medical follow-up and identification, referral and intervention for people identified with significant distress difficulties.
Study NCT05362071 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote Exercise Group
Description: The intervention will have a weekly frequency of two sessions on non-consecutive days during the first six weeks and three sessions on non-consecutive days for the remaining six weeks. The exercise intervention will consist of four 3-week mesocycles. The session's structure will consist of a warm-up, the main part, in which a combined training program will be carried out, consisting of three distinct blocks, and at the end, stretching. Blocks 1 and 2 will consist of three strength exercises with bodyweight and alternative materials and aerobic training. Between blocks 1 and 2, and later in block 3, participants will take a free walk with displacement in the space they have available in their own home. The session will end with stretching exercises for the main muscle groups. The sessions will last 37 to 57 minutes over 12 weeks, with approximately 5 min of warm-up and stretching, and the main part ranging from 27 min to 47 min throughout the intervention.
Study NCT05362071 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Group control
Description: Participants allocated to the GC will receive recommendations for the practice of physical activity based on information from three specific chapters of the Physical Activity Guide for the Brazilian Population (2021). The GC will receive through Whatsapp the information that is available in chapters 1, 4, and 5, which address the following topics: Understanding Physical Activity, Physical Activity for Adults, and Physical Activity for the Elderly. If sending via Whatsapp is not possible, the booklet will be printed and delivered to the participant. At the end of the 12 weeks, the same booklet will be made available to IG participants.
Study NCT05878275 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parent Informational Session
Description: Parents will receive a brochure on the importance of tummy time and limiting baby gear and watch a video on the importance of tummy time and limiting baby gear and receive support for implementing tummy time if requested.
Study NCT05181553 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Canada's Food Guide principles (CFG diet)
Description: 28-day fully controlled dietary intervention during which participants will receive a diet that reflects the recommendations of Canada's Food Guide.
Study NCT05181553 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard North American diet (NAD diet)
Description: 28-day fully controlled dietary intervention during which participants will receive a diet that reflects the eating habits of Canadians.
Study NCT06187402 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LM-24C5
Description: Administered intravenously
Study NCT06261424 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: IMPACT - rehabIlitation prograM for sPAstiC aTaxias
Description: The rehabilitation program will last 12 weeks and consists of three training sessions of 60 minutes per week (2 sessions in a therapy room and 1 session in an adapted pool with multiple levels of water) for a total of 36 sessions. Participants will be divided into 7 subgroups of 6 participants and each sub-group will be supervised by one physiotherapist (PT) and one physiotherapy technologist for safety considerations. It will focus on these three domains: 1) postural control; balance, trunk-limbs and multi-joints control and coordination and 3) functional mobility. Each domain contains a standardized list of exercises with different difficulty levels and specific times allocation. All exercises will be executed by the participants at each session at the appropriate difficulty level. The initial level of difficulty for each exercise will be determined by the PT based on individual results of the pre-intervention assessment and on individual performance, fatigue level and safety.
Study NCT06443489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-4849
Description: SHR-4849
Study NCT04570293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5% lidocaine medicated plaster
Description: The 5% lidocaine medicated plaster is measuring 10 cm x 14 cm contains 700 mg lidocaine (5% w/w) For each patient, the painful area and the trigger point will be chosen for treatment. The investigator will instruct the patient to replace the patch every 12 hours. The patches could be applied during the night (application in the evening and removal in the morning), or during the day. Patients will be told to apply up to three patches at one time.
Study NCT04570293 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: vehicle plaster
Description: Vehicle patches are identical to the active patch, except for the absence of lidocaine, without any optical differences.For each patient, the painful area and the trigger point will be chosen for treatment. The investigator will instruct the patient to replace the patch every 12 hours. The patches could be applied during the night (application in the evening and removal in the morning), or during the day. Patients will be told to apply up to three patches at one time.
Study NCT04931901 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EMG TOF device
Description: Use of Stimpod NMX450X as an electromyographic neuromuscular monitor
Study NCT04931901 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EMG TOF device
Description: Use of Stimpod NMX450X as an electromyographic neuromuscular monitor
Study NCT05771545 — intervention group
Intervention type: OTHER
Intervention: Telepsychiatry
Description: Instead of coming to the hospital physically, the attending psychiatrist will evaluate the patient via a video-link.
Study NCT05678335 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hydroxychloroquine
Description: Oral hydroxychloroquine 200mg twice daily for 12weeks.
Study NCT05678335 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus
Description: Oral Tacrolimus 1-2mg twice daily for 12 weeks.
Study NCT05583188 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Aliya Pulsed Electric Fields (PEF) ablation
Description: Patients will undergo PEF ablation
Study NCT05583188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab plus Platinum Doublet Chemotherapy
Description: If EGFR/ALK mutation negative, patients will receive standard of care dosing of three cycles of nivolumab at a dose of 360 mg every three weeks along with a platinum-based chemotherapy doublet (cisplatin or carboplatin plus pemetrexed for adenocarcinoma, cisplatin or carboplatin plus docetaxel, paclitaxel, or gemcitabine for squamous NSCLC) post-PEF ablation followed by resection.
Study NCT05583188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of care neoadjuvant therapy
Description: Patients not eligible for neoadjuvant nivolumab plus chemotherapy will receive standard of care systemic therapy post-PEF ablation followed by resection.
Study NCT05583188 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surgical Resection
Description: Patients not eligible for systemic therapy will receive definitive surgery without neoadjuvant therapy as per institutional standard of care post-PEF ablation.
Study NCT05379296 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Prevention Program Plus (DPP+)
Description: The DPP+ includes the CDC-approved DPP lifestyle program expanded to include a CDC-approved module on hypertension prevention and treatment
Study NCT05379296 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Diabetes Prevention Program (DPP)
Description: CDC-approved DPP lifestyle program
Study NCT05313165 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LimFlow Stent Graft System
Description: Creation of an arteriovenous fistula in the desired limb location
Study NCT05492058 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tactile stimulation group
Description: The tactile stimulation group will be asked to touch their own abdomen during the NST procedure.
Study NCT05492058 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: listen music
Description: Pregnant women in the music group will listen to a song they want with headphones during the NST procedure.
Study NCT05492058 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: virtual reality group
Description: Pregnant women in the virtual reality group will be shown a nature walk video with nature sounds (stream, bird, etc.) during the NST procedure.
Study NCT05508022 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Breathing exercise
Description: Before the enema is applied, breathing exercises will be applied to the participants in the intervention group.
Study NCT04794270 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism - TAM 24
Description: TEST
Study NCT04794270 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACUVUE OASYS® 1-Day for Astigmatism
Description: CONTROL
Study NCT03779659 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Synapse TENS device
Description: At the time of local anesthetic application the TENS device will be activated and placed on the buccal and lingual alveolar mucosa adjacent to the tooth receiving the restorative treatment using the pad applicator. The tip of the device with the electrodes are placed in a vertical up and down motion for approximately ten seconds. Following this, the level of pain and anxiety are measured using the Wong Baker Scale and Visual Analog Scale. The TENS device is used for achieving localized pain relief at the site of local anesthetic injection prior to injecting the anesthetic agent (such as lidocaine or articaine). Following this, once the clinician ensures that the patient is pain free then local anesthetic injection is given and following that the dental procedures are conducted.
Study NCT03779659 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical anesthetic gel
Description: The local anesthetic gel is typically used for achieving localized pain relief at the site of local anesthetic injection and this is part of standard care that is followed prior to dental procedures.~The amount of local anesthetic used will not exceed the maximum allowable dose, which will be calculated for each patient based on his/her age and weight prior to the dental procedure
Study NCT05189912 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Specimen retrieving bag
Description: Specimen retrieving bag was used to retrieve resected polyps.
Study NCT05189912 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sucking polyps to the instrument channel port
Description: Remove the colonoscope suction valve and connect a polyp trap to suction onto the instrument channel port.
Study NCT05347836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ELISA
Description: Determination of serum levels of sCD14 and sCD163 using ELISA
Study NCT06037746 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graston
Description: For the application, the individual was asked to lie face down, flex the knee to 90 degrees and release the ankle. The therapist took a position next to the individual on the side to be treated. Application was applied to the entire plantar fascia for 10 minutes in the longitudinal, vertical and oblique directions.
Study NCT06037746 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Percussive massage
Description: For the application, the individual was asked to lie face down, flex the knee to 90 degrees and release the ankle. The therapist took a position next to the individual on the side to be treated. Application was applied to the entire plantar fascia for 5 minutes in all directions without being bound to a single direction.
Study NCT06371222 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivabradine
Description: 5 mg for 3 months
Study NCT06371222 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Beta blocker
Description: controlled group
Study NCT06185582 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cowhage
Description: 25 spicules will be inserted in the center of the predefined skin area on the mandibular area. The spicules will be gently rubbed for 15-20 seconds in circular motion to facilitate epidermal penetration.
Study NCT05157100 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ingrezza Pill
Description: Participants will receive Ingrezza 40 mg and 80 mg tablets for 12 weeks.
Study NCT05519514 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cortiment
Description: Budesonide 9 mg prolonged release tablets
Study NCT05519514 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Budesonide
Description: Experimental (Budesonide 9 mg prolonged release tablets)
Study NCT05770037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alectinib
Description: Adult participants will be administered alectinib orally at a dose of 600 mg (four 150 mg capsules) twice daily.~Paediatric participants with a body weight ≥40 kg and who are able to swallow the capsules, will be administered alectinib orally at a dose of 600 mg (four 150 mg capsules) twice daily.~Each cycle of treatment will consist of 28 days and participants may continue on treatment until disease progression, unacceptable toxicity or withdrawal of consent.
Study NCT05842759 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Monitoring
Description: Continuous blood pressure monitoring
Study NCT05842759 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Norepinephrine preparation
Description: Norepinephrine infusion will be prepared and connected to peripheral or central venous catheter (infusion will not be started)
Study NCT05842759 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Propofol administration
Description: Propofol infusion will be started only when clinical effects of opioid are noticeable: 1.5 mg/kg propofol in patients less than 55 years old and 1.0 mg/kg propofol in patients 55 years or older over 90 seconds
Study NCT05842759 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Alarm adjustment
Description: Lower mean arterial pressure alarm threshold will be set to 75 mmHg