AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05072574 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specific dietary treatment and follow-up using coaching techniques
Description: Intervention group will receive specific dietary treatment and follow-up using coaching techniques, supported by new technologies, and will attend a nutritional education program
Study NCT04479683 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FTH then DH support
Description: FTH output and DH relay one day a week until the minimum healthy weight. This treatment combines over one day a medical evaluation by a senior psychiatrist, family work (parents group and multi-family therapy session), a therapeutic education group, a cognitive remediation group and a dietary follow-up with therapeutic meals.~During this phase, all children are evaluated once a week on a somatic level.
Study NCT04479683 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: standard care
Description: continuation of full-time hospitalization until the minimum healthy weight is reached, defined as the weight corresponding to the return to the previous BMI corridor (previous BMI +/- 1 BMI corridor, e.g. change from 25th to 10th percentile). This management combines bi-weekly medical follow-up by a senior psychiatrist, weekly family work, weekly therapeutic education group, weekly cognitive remediation group and bi-weekly dietary follow-up with therapeutic meals.
Study NCT05015790 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: virtual reality Bliss Solution
Description: use virtual reality Bliss Solution
Study NCT05794074 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: luteine and zeaxanthine
Description: luteine and zeaxanthine
Study NCT05339594 — intervention group
Intervention type: DEVICE
Intervention: NeuraGen
Description: NeuraGen nerve guide is an absorbable implant for the repair of peripheral nerve gaps.
Study NCT05339594 — intervention group
Intervention type: DEVICE
Intervention: NeuraGen 3D
Description: NeuraGen 3D Nerve guide matrix is a resorbable implant for the repair of peripheral nerve gaps.
Study NCT05593614 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATX01 10%
Description: A 100 mL bottle of hydrogel formulation containing 10% amitriptyline hydrochloride w/w
Study NCT05593614 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATX01 15%
Description: A 100 mL bottle of hydrogel formulation containing 15% amitriptyline hydrochloride w/w
Study NCT06481514 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Interpretation of the CTG using FRI score
Description: At each of the components of the score will be assigned a score of 1 if the variable evaluated is considered normal, 0 if classified as abnormal. To encourage a simplified clinical interpretation of the different scores obtained (score from 1 to 8) they will be classified into 3 risk categories: Score 5-8: green zone, Score 3-4: zone yellow, Score 1-2: red zone. An FRI of 1-2 (red zone) is to be considered as anomalous
Study NCT06481514 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Classic interpretation of the CTG
Description: evaluate the CTG of group B patients according to the usual internal management protocols
Study NCT05593614 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A 100 mL bottle of hydrogel formulation containing no active substance
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: evaluation of muscle function
Description: Myogrip (≥ 6 years): precise dynamometric measurement of gripping force, measuring force in Newton up to 90kg with 0.01kg resolution. It's evaluated at D0, M6, M12, M18, and M24 Myopinch (≥ 6 years) : measure thumb-index force up to 15 kg with a resolution of 0.001 kg using a precision sensor equipped with two steel distance blades. It's evaluated at D0, M6, M12, M18, and M24
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: First-line cognitive assessment
Description: Vineland-II (All patients) : is a scale for assessing adaptive behaviors. will be carried out during the telephone call at M1/V2.~All tests are evaluated at D0, and M18 :~Bayley-4 language part (\< 42 months) PVSE (≥ 4 years) CELF-5 (≥ 5 years) Conners-3 (≥ 6 years) AQ (≥ 4 years), EQ (≥ 11 years)~M-CHAT-R (\< 4 years) :~SRS-2 (≥ 2 years)
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: second-line cognitive assessment
Description: In the event of positive cognitive screening at D0 or M18, a second-line cognitive assessment will be carried out at a subsequent visit. A list of tests is proposed below, but will be adapted according to the tests available at each center.~* EVALO BB (0-2 years) or EVALO (2-6 years) or full CELF-5 (5-18 years) following positive screening in the communication domain of first-line tests (Vineland II communication domain, Bayley 4, CELF-5 pragmatic profile)~* FEE and DSM-5 diagnostic criteria for ADHD (from age 6 only) following positive screening in the attention and executive functions domain of first-line tests (Conners 3, BRIEF)~* M-CHAT-R/F (\< 4 years) or SCQ (≥ 4 years) and ADOS-2 (≥ 12 years) following a positive screening in the area of social cognition and autistic traits on first-line tests (Vineland II, M-CHAT-R, SRS-2, EQ, AQ).
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cardiac evaluation
Description: All tests are evaluated at D0, M12, and M24 :~Electrocardiogram (ECG) : This examination will be carried out in accordance with the 12 leads recording the following parameters: verification of sinus rhythm, P wave, PR interval, QRS complex (interval), ST segment, T wave, QT complex, heart rate.~Cardiac ultrasound: Non-invasive ultrasound will focus on the following parameters measured from 2-dimensional images, to look for cardiomyopathy and/or structural abnormality:~* end-diastolic/end-systolic diameter/left ventricular ejection fraction~* Septal wall thickness / left ventricular posterior wall~* Fractional shortening 24-hour Holter-ECG : This examination consists of a continuous test recording the heart rhythm for 24 hours.
Study NCT06321965 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: MRI
Description: Cerebral MRI : Performed at D0, only for patients with ASI type 1 ≥ 6 years, or younger patients for whom the investigator considers that the examination can be performed without sedation or general anesthesia. It will include sequences:~* 3D T1, gradient echo, 1.1 mm voxel, sagittal acquisition~* axial T2, spin-echo, slice thickness 4 mm~* 3D FLAIR, spin-echo, 1 mm voxel, sagittal acquisition Muscular MRI: performed at V1/J0, and V6/M24. The examination will include water-fat imaging (Dixon) in full-body, 3D mode, with proton density weighting and millimeter resolution.
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Assessment of activity and muscle fatigue
Description: Syde® : evaluated at D0, M6, M12, M24. Patients aged 2 and over will receive the Syde® wearable device to collect their daily activities.~Muscular endurance tests (≥ 6 years) : evaluated at D0, M12, M24 ( only one of 3 tests based on motor function level) oESNHPT : In this test, patients are asked to walk a 10-meter path. oESBBT : In this test, patients have to move 10 blocks over a partition. oESWT: In this test, patients must repeatedly place and remove 9 sticks in 9 holes.~PedsQL Fatigue (≥ 2 years): evaluated at D0, M12, M24. Scale designed to measure fatigue in patients with acute and chronic conditions, as well as in healthy school and community populations.~Fatigue rating scale (≥ 6 years): evaluated at D0, M12, M24. The fatigue assessment scale has 11 numerical points ranging from 0 to 10. The patient is asked to give a rating that best reflects his or her perception of fatigue at that particular moment.
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Assessment of bulbar function
Description: DDD-pNMD (≥ 2 years) : evaluated at D0, M6, M12, M18, and M24, is a list of 9 questions used by doctors to screen for dysphagia and dysarthria.~NdSSS (All Patients) : evaluated at D0, M6, M12, M18, and M24, is an 8-level scale for assessing swallowing.~TOMASS-c : (≥ 4 years of age, in patients able to eat solids safely, after assessment of the risk of a false route by the speech therapist): this is a score designed to assess mastication when eating a cracker. Age-dependent standards exist for different types of cracker.~- Fluid intake test (> 110 cm, in patients able to drink a liquid safely, after assessment of the risk of a false route by the speech therapist): swallowing limit.
Study NCT06067503 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-fluorofuranylnorprogesterone
Description: The dose of the investigational imaging agent, FFNP, is approximately 7 millicurie (mCi) (259 megabecquerels (MBq)), IV slow infusion over approximately two minutes followed by saline flush.
Study NCT06067503 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Liquid Biopsy
Description: 20ml of whole blood will be collected into two Ethylenediaminetetraacetic acid (EDTA) tubes at each timepoint, CTCs are isolated using the microfluidic Versatile Exclusion-based Rare Sample Analysis (VERSA) platform that integrates CTC capture with RNA extraction on a single chip using Exclusion-Based Sample Preparation (ESP) technology
Study NCT06067503 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography/Computed Tomography
Description: FFNP drug in combination with PET/CT scans to image participant
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Evaluation of body composition and metabolism
Description: Food survey : The dietary survey questionnaire will be sent to parents at D0 and M18. Parents will be asked to complete it for 3 days before the M6 and M24.~Bioelectrical impedancemetry: Evaluated at M6 and M24. Renal ultrasound: Evaluated at M6, is a non-invasive examination that analyzes the appearance of the kidney and urinary tract.~Dual-energy X-ray absorptiometry (DXA) : Evaluated at M6, it measures body composition using spectral imaging, including fat mass, lean mass and bone mineral density.~Fibroscan : Evaluated at M6 and M24. This examination uses pulse elastography to measure liver elasticity, which provides information on the presence of hepatic fibrosis, and sound attenuation, which provides information on the presence of liver fat overload.~Indirect calorimetry : Evaluated at M6. This device enables precise measurement of Resting Energy Expenditure , Respiratory Quotient and metabolic substrate oxidation.
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: SMAIS : The questionnaire has been developed specifically for ASI. At D0, M6, M12, M18 and M24.~HUI2 : specializes in preference-based measures of health-related quality of life. At D0, M6, M12, M18 and M24.~Peds QL : is a modular instrument designed to measure health-related quality of life and disease-specific symptoms. At D0, M6, M12, M18 and M24.~Neuromuscular module : 17 disease-related items. It is evaluated at D0, M6, M12, M18 and M24.~Family impact module : It measures parents' reported physical, emotional, social and cognitive functioning, communication and concerns. At D0, M12, and M24.~ASI cost questionnaire: At visit 1 (D0): This questionnaire, completed by the parents, includes information on occupation, parents' working hours and any reduction in them due to the child's pathology, the number of working days missed by the parents or school days missed by the child, and disability-related costs.
Study NCT06321965 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Biocollection
Description: A blood bio collection (optional) will be offered to patients at D0, M6 , M12, M18, M24.~Patients receiving intrathecal injections will also be offered the opportunity to participate in a CSF (cerebrospinal fluid) biocollection (optional).
Study NCT06321965 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Skinfold measurement
Description: The tricipital point should be marked on the posterior aspect of the arm, on the midline of the tricipital muscle, midway between the acromion and the radius. At D0, M6, M12, M18 and M24
Study NCT05114785 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multi Parametric Cardiac Magnetic Resonance
Description: Research based Cardiac MRI evaluation to determine cardiovascular haemodynamics
Study NCT04890223 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief MI intervention
Description: Brief MI intervention
Study NCT04890223 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo intervention
Description: Generic health advice consultations and self-help smoking cessation booklets
Study NCT05863910 — intervention group
Intervention type: DRUG
Intervention: Medical Cannabis
Description: Any cannabis product that is available to participants through the Medical Cannabis Access Program is eligible to be included in this study.
Study NCT06160193 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief behavioral parent training with optional care as usual
Description: A brief behavioral parent training program that combines individually-tailored stimulus control and contingency management techniques to treat children's behavioral difficulties in two (bi)weekly training sessions of 120 minutes, and a third session of 60 minutes, in which the training will be evaluated and maintenance training will be provided.
Study NCT06160193 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Care as usual
Description: Care as usual may include all mental health care that is usually provided within or outside (e.g., at a child mental healthcare institution or at school) the general practitioners practice, except from pharmacological treatment for children's behavioral difficulties and/or behavioral parent training/support, up until the first posttreatment assessment (T1). Care as usual can also imply that there is no support or treatment.
Study NCT06160193 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care as usual
Description: Care as usual may include all mental health care that is usually provided within or outside (e.g., at a child mental healthcare institution or at school) the general practitioners practice, except from pharmacological treatment for children's behavioral difficulties and/or behavioral parent training/support, up until the first posttreatment assessment (T1). Care as usual can also imply that there is no support or treatment.
Study NCT05446584 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: HD-tDCS for this study is not intended to be a treatment, and will be applied continuously for 30 minutes at sham (0 mA) or 2 mA for active conditions across 3 consecutive daily sessions to probe neural circuit integrity. This specific HD-tDCS device is completely computer driven, running on a laptop using specialized software. Circular electrodes (12-mm in diameter) filled with conductive gel will be placed in a 4x1 ring configuration with the central electrode being the anode surrounded by four cathodes.
Study NCT05446584 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: High Definition Transcranial Direct Current Stimulation
Description: HD-tDCS for this study is not intended to be a treatment, and will be applied continuously for 30 minutes at sham (0 mA) or 2 mA for active conditions across 3 consecutive daily sessions to probe neural circuit integrity. This specific HD-tDCS device is completely computer driven, running on a laptop using specialized software. Circular electrodes (12-mm in diameter) filled with conductive gel will be placed in a 4x1 ring configuration with the central electrode being the anode surrounded by four cathodes.
Study NCT05544331 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise group (written form)
Description: The exercise program will be structUred with core stabilization exercises. Patients will be given the written form of exercises and will be applied as home exercises. Exercise progression will be provided by position changes.
Study NCT05544331 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise group (video based)
Description: The exercise program will be structUred with core stabilization exercises. Patients will be given the exercise videos, which provide visual and auditory feedback, and will be applied as home exercises. Exercise progression will be provided by position changes.
Study NCT05622435 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: T10070, Plastic tube with a roll-on applicator filled with an ointment
Description: 6 times per day on both (upper and lower) eyelids of right eye during 7 to 9 days.
Study NCT06196398 — intervention group
Intervention type: DRUG
Intervention: Standard Medical Treatment on the basis of anti-platelet therapy
Description: 1. Anti-platelet therapy: aspirin 75mg+clopidogrel 100mg will be applied for patients with severe ICAS stenosis (70%-90%) suffering stroke or TIA within 30 days. After 90 days, single anti-platelet therapy will be continued.~2. Intensive statin therapy: Statins with high doses~3. Blood pressure: below 140/90mmHg~4. LDL: less than 1.81mmol/L(70mg/dl)~5. Fasting blood glucose controlled to 5.9mmol/L, and glycosylated hemoglobin A1c reduced to less than 7%~6. Cigarette and alcohol quitting~7. Oral anticoagulants for atrial fibrillation
Study NCT06519383 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: guided implant surgery
Description: Surgical guide is fabricated and fitted onto the patient's arch and implant is placed with guide in place.
Study NCT04764734 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NightOwl
Description: The NightOwl is a finger-mounted home sleep apnea testing device
Study NCT06516263 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Leukocyte and platelet rich fibrin
Description: Formation of an Leukocyte and platelet rich fibrin clot and placement into the osteotomy site prior to implant placement
Study NCT06516263 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Standard implant placement
Description: Standard implant placement without Leukocyte and platelet rich fibrin
Study NCT05107973 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baduajin
Description: The intervention will consist in a 1 hour supervised Baduajin sessions conducted once a week a certified instructor with more than 10 years of experience. Each session will start with 5 min of warm up, 50 minutes of Baduajin and 5 min of cool down. In the main part the participants exercise the wholes set of Baduajin that consist of eigth forms.
Study NCT05128006 — intervention group
Intervention type: OTHER
Intervention: New patient teledermatology visit
Description: new patient teledermatology visits
Study NCT04932213 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tropicamide Ophthalmic
Description: Tropicamide eye drops are used for dilating pupils (mydriasis) to do comprehensive fundus examination.
Study NCT04965922 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Multimodal intervention
Description: The intervention consists of identifying the individual needs of each caregiver and patient and identifying sources of improvement in the management of daily life, including the optimization of social support. This optimization requires the involvement of people in the environment (family, friends, neighbours) who can provide help, support of any kind, recurrent or punctual, minimizing negative family interactions and maximizing positive contributions by each in supporting and supporting the individual.~The intervention is personalized in the sense that the content of each session seeks to adapt itself to the specificities of the couple situation and its surroundings.~interviews/meetings involving a psychologist social worker.
Study NCT04965922 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multimodal intervention
Description: The intervention consists of identifying the individual needs of each caregiver and patient and identifying sources of improvement in the management of daily life, including the optimization of social support. This optimization requires the involvement of people in the environment (family, friends, neighbours) who can provide help, support of any kind, recurrent or punctual, minimizing negative family interactions and maximizing positive contributions by each in supporting and supporting the individual.~The intervention is personalized in the sense that the content of each session seeks to adapt itself to the specificities of the couple situation and its surroundings.~interviews/meetings involving a psychologist social worker.
Study NCT05476432 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: HAIC
Description: The microcatheter was advanced into the hepatic artery, and patients were transferred to the inpatient ward for drug infusion via the hepatic artery
Study NCT05476432 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HAIC
Description: The microcatheter was advanced into the hepatic artery, and patients were transferred to the inpatient ward for drug infusion via the hepatic artery
Study NCT05476432 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: FOLFOX 2d
Description: Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 46 hours
Study NCT05476432 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFOX 1d
Description: Oxaliplatin, leucovorin, bolus fluorouracil, and infusional fluorouracil 2400 mg/m² over 23 hours
Study NCT05650138 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Jacobson's progressive muscular relaxation technique
Description: subjects will receive Jacobsons muscle relaxation technique. Patients will be demonstrated with the technique to contract and relax various groups of muscles, to coordinate contractions and relaxations with deep breaths and to perform the entire procedure with eyes closed in supine lying down position. Every subject will perform this supervised relaxation for 6 repetitions during a single session on once a day basis for four weeks.
Study NCT05650138 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 30 min walk
Description: 30 minutes walk twice a week for 4 weeks
Study NCT05650138 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 30 min walk
Description: 30 minutes walk twice a week for 4 weeks