AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06542575 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DTx-guided HBCR
Description: The Huaxiaoxin WeChat mini program incorporating the core components of guidelines are divided into two main sections. Section 1 comprises interventions such as exercise training, educational programmes and cardiovascular risk factor management. Section 2 provides a secure platform for individualized feedback, just-in-time two-way communication, remote data transmission, and data repository, allowing patients and healthcare providers to access all relevant files anytime and anywhere throughout the 12-month study period.
Study NCT05551637 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Kazu Gain Gold
Description: Kazu Gain Gold is an Oral Nutritional Supplementation made by AIWAIDO Food Joint Stock Company.~Condition: Powder~Color: White to light yellow~Scent: The fresh scent of milk, gracious sugary smell.~Date of use: 24 months from the manufactured date.~User Manual: Mix 6 spoons of Kazu Gain Gold (equal to 49,2 grams) with 180 ml of warm water (The energy density reaches 1kal/ml). Consume 2 glasses per day or follow the directions from the medical staff. The product should consume less than 1 hour. Do not let the child eat the leftovers of the previous meal.~Preserve: Store in a clean, dry place, and keep away from direct sunlight. Opened can or package must be closed and used up within 3 weeks.
Study NCT05251129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin 80 Mg Oral Tablet
Description: Higher intensity statin
Study NCT05251129 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pravastatin 40 Mg Oral Tablet
Description: Lower intensity statin
Study NCT05375279 — intervention group
Intervention type: PROCEDURE
Intervention: Lip Salivary Gland Biopsy
Description: Obtaining few salivary glands from the partipants' lip that will be studied using the Congo Red staining method.
Study NCT05542108 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multisensory Stimulation and Family Education Group
Description: Bedside intervention directly with infant with trained healthcare providers and parents. Includes two parts: twice daily multisensory stimulation sessions and separate family education meetings completed with individual infant parent/s and trained operator.
Study NCT05542108 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Family Education Only Group (FEG)
Description: Bedside intervention directly with infant with trained healthcare providers and parents. Includes family education meetings completed with individual infant parent/s and trained operator.
Study NCT06366906 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: The Resnet50 deep learning (DL) model
Description: The predictive capability of the above Resnet50 deep learning (DL) model was validated in the test set. Based on the AUC and ACC, the best prediction model was identified. To explore the robust of the selected model, ROC analysis was performed the in the external validation set. Moreover, the Log-rank test was applied to evaluate the prognostic value of the model.
Study NCT05290311 — intervention group
Intervention type: BEHAVIORAL
Intervention: cognitive behavioural therapy
Description: Cognitive behavioural therapy (CBT) was given according to the protocol of Safren (2004, 2005). Each participant followed one session of 60 minutes per week, for 10 to 16 weeks. Psychotherapists giving CBT had at least a master diploma.
Study NCT05487274 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Total Shoulder Arthroplasty + augmented glenoid component
Description: Replacement of the shoulder joint (ball and socket, or humeral head and glenoid) using prosthetic components. A prosthetic component is also implanted to correct for the amount of bone loss in the shoulder and restore stability.
Study NCT05487274 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Reverse Shoulder Arthroplasty
Description: Replacement of the shoulder joint like the TSA, however the orientation of the ball and socket is reversed.
Study NCT05883956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Subcutaneous azacitidine
Description: Subcutaneous azacitidine, 75mg/m2, 7 days
Study NCT05883956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral decitabine/cedazuridine
Description: Oral decitabine 35mg/cedazuridine 100mg, once daily, 5 days
Study NCT06031792 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Piezo endodontic surgery
Description: Osteotomy will be done with Piezosurgery touch. After the soft tissue curettage and uncovering the root apex, the last 3 mm of the root apex will be resected perpendicular to the long axis of the tooth using piezotome. apical preparation will be performed and Biodentine®retrograde filling material will be placed. The flap will be re-approximated and interrupted suture using non-absorbable monofilament suture will be applied. Finally, Post-operative parallel Digital view.
Study NCT06031792 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional endodontic surgery
Description: After the soft tissue curettage and exposure of the root apex, the osteotomy will be performed using a conventional surgical handpiece. The same steps will be followed to prepare and restore the root, as well as to reposition the flap.
Study NCT04971668 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aromatherapy
Description: Three drops of the designated blend aromatherapy (ginger \& lavender) will be placed on a 2-inch by 2-inch impermeable, backed gauze pad and patient will be asked to inhale deeply and simulate like chewing gum for 5 minutes.
Study NCT04971668 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gum Chewing
Description: Patients will chew gum (sugar free) and inhale deeply with inert gauze for 5 minutes.
Study NCT04971668 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Controlled
Description: Patients will inhale deeply with inert gauze and simulate like chewing gum for 5 minutes.
Study NCT05684705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BV100
Description: Intravenous infusion
Study NCT05167409 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Evorpacept (ALX148)
Description: IV QW
Study NCT05167409 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: IV QW
Study NCT05167409 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV Q3W
Study NCT06100172 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN)
Description: This method of simultaneous vagal and trigeminal stimulation via the external ear is known as transcutaneous auricular neurostimulation (tAN), as the targets of electrical stimulation include the auricular branch of the vagus nerve (ABVN) and auriculotemporal nerve (ATN), which is a branch of the mandibular division of the trigeminal nerve. Electrodes applied to select dermatome regions can target ear neural structures and deliver non-invasive vagus nerve stimulation (VNS) and trigeminal nerve stimulation (TNS). Use of tAN for pain relief is an attractive alternative to pharmacologic and opioid-based approaches because it is safe and effective and presents no addiction liability.
Study NCT06100172 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Sham Control Device
Description: This device looks like the active device, but no stimulation will be delivered.
Study NCT05813548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FASTer Way Intervention
Description: 6-weeks of exercise, building healthy nutritional habits such as intermittent fasting and carb-cycling
Study NCT04719351 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The DIARY mobile application
Description: The mobile application has two main functionalities. First, it will remind the user to report in regular time periods on their mental health status (e.g., sleep disturbances, stress). The assessment is done daily for four weeks. Second, some completed assessments will be combined with a behavioral prompt i.e. short message encouraging the user to engage in one of the strategies that can help coping with stress at work, e.g. remember to take short breaks, exercise in daylight, summarize a day with a colleague after a finished shift.
Study NCT05695326 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3D printing technology learning program
Description: The study is aimed to evaluate a 3D printing technology learning program for rehabilitation professionals
Study NCT05813548 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group Intervention
Description: 6-weeks of following general exercise and nutrition guidelines from American Heart Association (AHA) and United States Department of Agriculture (USDA), respectively.
Study NCT05289518 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Remote ischemic conditioning (RIC)
Description: RIC is a non-invasive therapy which is performed by automated pneumatic cuffs placed on bilateral arms. The RIC protocol include five cycles of 5-min inflation to 220mmHg and 5-min deflation.
Study NCT05289518 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham remote ischemic conditioning (Sham-RIC)
Description: The Sham-RIC protocol include five cycles of 5-min inflation to 60 mmHg and 5-min deflation by placing automated pneumatic cuffs on bilateral arms.
Study NCT05132114 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Lugol's iodine test
Description: Intraoperative application of Lugol's iodine (i.e. staining of the cervix with Lugol's iodine solution)
Study NCT05011201 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual Joint Visual Feedback without Scoring
Description: Participants will walk on the treadmill while given instantaneous anterior and posterior foot position and immediate scoring information using the DJVF interface. A pediatric physical therapist will provide (1) verbal encouragement and redirection of attention to the task as needed (2) verbal cueing to assist if difficulty in interpreting the feedback and appropriate modification is noted.
Study NCT05011201 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dual Joint Visual Feedback with Scoring
Description: Participants will walk on the treadmill using the same DJFB with additional visual cumulative scoring on their performance. A pediatric physical therapist will provide (1) verbal encouragement and redirection of attention to the task as needed (2) verbal cueing to assist if difficulty in interpreting the feedback and appropriate modification is noted.
Study NCT04864587 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Artificial intelligence used for image recognition in pouchoscopy
Description: The aim of this study is to develop an image recognition algorithm that reliably detects the different graduations of pouch inflammation and neoplasms in the pouch
Study NCT04709133 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: multi-ligament knee surgery
Description: a chart review will be performed to identify patients who underwent surgical treatment for multi-ligamentous knee injuries at Assiut University Hospital performed by one of sports medicine orthopaedic surgeons at Assiut arthroscopy and sport unit.
Study NCT06166121 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ShenJu
Description: One package per time, twice a day, 90 days of treatment
Study NCT06166121 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: One package per time, twice a day, 90 days of treatment (the placebo was basically the same as ShenJu in terms of appearance, shape, color, taste, etc.)
Study NCT04135170 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: ALBC vs plain bone cement
Description: The patients undergoing full-cemented primary total knee arthroplasty are allocated to either ALBC or plain bone cement and compare the effectiveness of ALBC use vs pain bone cement bone cement without antibiotic) with respect to revision due to PJI one year after primary TKA surgery.
Study NCT04135170 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: ALBC vs plain bone cement
Description: The patients undergoing full-cemented primary total knee arthroplasty are allocated to either ALBC or plain bone cement and compare the effectiveness of ALBC use vs pain bone cement bone cement without antibiotic) with respect to revision due to PJI one year after primary TKA surgery.
Study NCT05172583 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: The control groups will receive the nursing interventions that are performed daily in the adult ICU. These are orientation in time, space, and place, accompaniment of the family for two hours in the morning and two hours in the afternoon, physical therapy once a day according to the patient's condition, medication with conscious sedation, and progressive reduction analgesics. opioids and benzodiazepines.
Study NCT05172583 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interventions to reduce delirium based on DSM and scientific evidence
Description: The interventions are designed from the structure of the Dynamic Symptoms Model (DSM), taking into account the antecedents of delirium, physiological such as the medical condition of mechanical ventilation and pain, and drug treatment with sedatives and analgesics; the psychological, social, and spiritual antecedents with stimulation in the values, life experience, personality and spirituality, and the environmental antecedents with an adaptation of the physical conditions of the ICU. In addition, previous experience with identification and care of concomitant symptoms such as fear, confusion, restlessness, loneliness, and discomfort, and with the measurement and classification of the trajectory of delirium when it occurs, will also be considered. The interventions follow the scientific evidence, mainly from the ABCDEF bundle. All interventions are non-pharmacological.
Study NCT04867252 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Resveratrol (1000mg twice a day), Myoinositol 1000mg (Twice a day)
Description: 51 Patients with PCOS receiving Resveratrol and Myoinositol 1000mg and 1000mg BD daily respectively
Study NCT04867252 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Metformin (500 mg Twice a day), Pioglitazone (15 mg Twice a day)
Description: 51 Patients with PCOS receiving Metformin and Pioglitazone 500 mg and 15 mg BD daily respectively
Study NCT06213688 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: blood sampling
Description: blood sampling at inclusion
Study NCT06213688 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: urine sampling
Description: urine sampling at inclusion
Study NCT05306470 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ethyl chloride
Description: Application of ethyl chloride for a cooling effect to numb the area for oral infiltration anesthetic
Study NCT05306470 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5% lidocaine gel
Description: Application of 5% lidocaine gel to numb the area for oral infiltration anesthetic
Study NCT04836000 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In addition to the conservative treatment, Low-level laser therapy
Description: For Experimental Group A Gallium-aluminum-arsenide (Ga-Al-As) diode laser instrument (Roland Serie, Elettronica Pagani, Paderno, Italy, Mod IR 27/1) will be used (wavelength 904 nm, 5500 Hz frequency, 27 W maximum power output per pulse, 13.2 mW average power, 0.8-cm2 spot size, 1.6 J of total energy will be delivered per point at each session at a power density of 16.5 mW/cm2, and the cumulative energy per point for all sessions was 16 J).~Ga-Al-As laser therapy will be applied to experimental group patients two times per week for 6 weeks in 10-min sessions. LLLT will be applied over the tuberculum majus and minus, the anterior and posterior faces of the capsule, and the subacromial regions. Each point will be treated for 120 sec. The head of the instrument will be held perpendicular to the body surface and in skin contact without pressure.
Study NCT04836000 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: In addition to the conservative treatment, Low-level laser therapy (turned off)
Description: For Placebo Group In the placebo group, laser instrument will be applied in the same way but the device will be turned off during treatment sessions. Patients and physiotherapist will be asked to use protective eyeglasses during therapy for safety.
Study NCT04836000 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative treatment solely
Description: For Control Group All patients using an immobilization bandage up to post-operative 6th week will receive the standardized 6-week supervised rehabilitation program advocated by the same physiotherapist (CK), 7 years of experience in the clinical treatment of rotator cuff tear, after the baseline assessment. Composed of 30 treatment sessions (five days/week) of 45 to 60 minutes, the rehabilitation program will be provided individually to all participants. Physiotherapy sessions will be devoted to strength, mobilizations, stretching, perturbation, and sensorimotor training using motor control exercises, hence, to restore adequate shoulder neuromuscular control. The treatment program will also be included patient education.
Study NCT06250010 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: tissue samples (healthy and tumor taken from the same patient) and tissue samples (decidualized endometrium and trophoblast taken from it patient)
Description: Correlation between the immuno-score results of each patient with his prognosis, in terms disease-free survival, overall survival, relapse-free survival, disease-specific survival cancer, distant and/or local free survival, to validate their potential role independent in the progression of endometrial cancer; later, for a better characterization of the various ones risk classes, we will combine our immuno-score with the already known risk factors, included in the ESMO-ESGO-ESTRO classification and in the biomolecular classification of endometrial cancer, to investigate whether the Microenvironmental immunological factors in endometrial cancer could allow better stratification of patients in risk classes.
Study NCT05009901 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alpha Lipoic Acid 600 MG Oral Tablet
Description: Alpha lipoic acid 600 mg daily for 8 weeks
Study NCT05009901 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo one tablet daily for 8 weeks
Study NCT05442710 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ARTICE
Description: Extracorporal treatment with purified granulocyte concentrate
Study NCT04688203 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium Sulfate Injection
Description: will receive IV bolus dose of 40mg/kg magnesium sulfate in 100 ml saline solution over ten minutes then continuous infusion of 10-15mg/kg/h will be titrated till achieve target mean arterial blood pressure (55-65 mmHg) and will be terminated by the end of surgery.
Study NCT04688203 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Labetalol Injectable Solution
Description: will receive IV bolus does of labetalol 0.25 mg/kg over ten minutes then continuous infusion of 0.5-1mg/kg/h will be titrated till achieve target mean arterial blood pressure (55-65 mmHg) and will be terminated by the end of surgery.
Study NCT06403930 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Maxillary Obturator
Description: Maxillary obturators are prosthetic devices used to close maxillary defects resulting from surgical removal of part or all of the maxilla bone due to conditions like tumors or congenital anomalies. They separate the oral and nasal cavities, restore speech, swallowing, and mastication functions, provide facial support, and improve aesthetics and quality of life.
Study NCT06403930 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Maxillary Obturator
Description: Maxillary obturators are prosthetic devices used to close maxillary defects resulting from surgical removal of part or all of the maxilla bone due to conditions like tumors or congenital anomalies. They separate the oral and nasal cavities, restore speech, swallowing, and mastication functions, provide facial support, and improve aesthetics and quality of life.
Study NCT06427057 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab plus chemotherapy
Description: AK104 (10mg/kg ,Q3W，intravenously) plus chemotherapy（e.g. gemcitabine or albumin paclitaxel，dosage based on guidelines or instructions）
Study NCT06427057 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cadonilimab plus TKI
Description: Patients will receive AK104 (10mg/kg ,Q3W，intravenously) plus TKI（e.g. sunitinib, pezopanib，dosage based on guidelines or instructions)
Study NCT04734288 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vit.D3 5000 IU, Immune Active
Description: The subjects will receive monthly (for either 3 or 6 months):~1. Vit.D3 5000 and Immune Active. The first phase includes 3 months of treatment and the second phase includes 6 months of treatment.~2. An in-home Vit.D/ hs-CRP test kit and asked to self-administer a blood collection via fingerstick and return the kits for analysis within a few days.~3. Two online questionnaires each month and asked to fill them out within a few days. It will either be the Medical Outcomes Study (MOS) Short Form (SF)-36 and the Health Status Baseline or Health Status Follow-up Questionnaire.
Study NCT06373705 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cardiac simulator
Description: A computer software cardiac simulator for surgical planning in complex Congenital Heart Disease (CHD) pediatric patients.
Study NCT05394038 — intervention group
Intervention type: OTHER
Intervention: None，observational study.
Description: observational study