AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06256419 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: responders group and nonresponders group
Description: For all the patients with type 2 diabetes who were initially enrolled in the study, blood samples were obtained for genotyping before the administration of GLP-1 receptor agonists. Patients were re-screened according to whether they had used GLP-1 RA continuously for more than 6 months and had completed the specified follow-up tasks.~Patients were divided according to the type of T2DM susceptibility genes. Or all were divided into responses group and nonresponses group according to whether they had glycemic response (△HbA1c↓ ≥1.0%) and weight response (△weight↓ ≥3.0%) after taking GLP-1 receptor agonist for 6 months.~According to the above grouping, the variables that can predict the efficacy of the drug were identified, and the weight of the influence of these variables on the efficacy was evaluated.
Study NCT05730192 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CADDIE
Description: A colonoscopy is an examination of the bowels using a colonoscope, or a thin, flexible tube with a light and camera. It can help identify issues like colorectal cancer, polyps, and ulcers.
Study NCT04925466 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CPAP at pressure of 10 cmH2O
Description: Patients used CPAP with the pressure of 10 cmH2O during overnight polysomnography
Study NCT04925466 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CPAP at minimal effective pressure
Description: Patients with OSA will be treated with CPAP at minimal effective pressure derived from manual titration during sleep.
Study NCT05730192 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CADDIE
Description: A colonoscopy is an examination of the bowels using a colonoscope, or a thin, flexible tube with a light and camera. It can help identify issues like colorectal cancer, polyps, and ulcers.
Study NCT04915755 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: Niraparib will be administered.
Study NCT05901688 — intervention group
Intervention type: OTHER
Intervention: Umbilical cord measurements & observations
Description: In the screening study of an unselected population at 20-22 weeks' and 35-37 weeks' gestation, women are offered an ultrasound scan as part of standard care and will be invited to take part in the study which will involve taking the following additional ultrasound measurements:~1. Umbilical cord coiling index (UCI)~2. Transverse diameter of umbilical cord (UC)~3. Transverse diameter of umbilical vein (UV) and artery (UA)~4. Umbilical vein (UV) Doppler flow characteristics~5. Presence of nuchal cord
Study NCT04915755 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo will be administered
Study NCT05453929 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rocuronium for deep NMB
Description: Deep neuromuscular blockade will be maintained using continuous infusion of rocuronium.
Study NCT05453929 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rocuronium for moderate NMB
Description: Moderate neuromuscular blockade will be maintained using continuous infusion of rocuronium.
Study NCT04851041 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Potato
Description: Controlled human intervention trial to evaluate the impact of boiled potato intake as part of a healthy dietary patterns on cardiometabolic health
Study NCT04851041 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pasta/rice
Description: Since potatoes, white rice and white pasta are all products with a high glycemic index and concomitant relatively steep glucose excursions after intake, this intervention group helps to compare the effect of potato vs another high glucemic index food.
Study NCT05089682 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DBS Stimulation during sleep
Description: Open and closed-loop electrical modulation triggered and based on ongoing sleep staging by researcher as well as automated closed-loop algorithm for stimulation.
Study NCT04657614 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neutral Alignment
Description: Alignment that is a neutral replicate of the participants prescribed prosthesis.
Study NCT04657614 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Anterior Alignment
Description: Alignment that is anterior displaced pylon.
Study NCT04657614 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Posterior Alignment
Description: Alignment that is posteriorly displaced pylon.
Study NCT05568654 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Rapid Diagnostic Testing
Description: Eligible patients in hospitals randomized to this arm will undergo testing for viral pathogens (from November-April) and pneumococcal UAT testing. A CDSS-based alert will be generated in real time. If the patient is not being admitted to the intensive care unit, the form will append orders for viral pathogen and UAT testing.
Study NCT05568654 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pharmacist-led de-escalation
Description: A CDSS algorithm will identify CAP patients who meet study criteria and have negative culture results for greater than 48 hours and generate a list for the antimicrobial stewardship pharmacist, who will be a member of the study team. The alerts will be audited by the pharmacist daily at a centralized location. The pharmacist will attempt to determine whether each patient is clinically stable. The validated measures of clinical stability in patients with CAP are a) resolved vital sign abnormalities (temperature, heart rate, oxygen saturation, blood pressure and respiratory rate) b) normal mental status and c) ability to eat. If the patient appears stable, the pharmacist will communicate their recommendations for de-escalation to the clinical providers via a phone call or page. The de-escalation recommendations made by the pharmacist will be based on a protocol developed by the research team.
Study NCT04780763 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Milk product fermented by lactic bacteria or not fermented
Description: 2 bottles of 100g consumed daily during 28 days
Study NCT04780763 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Milk product fermented by lactic bacteria or not fermented
Description: 2 bottles of 100g consumed daily during 28 days
Study NCT06171776 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RetroMTA
Description: calcium silicate lining material work as dentin substitute
Study NCT06171776 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TheraCal
Description: calcium silicat material light cured
Study NCT06171776 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fuji IX
Description: filling material bonded chemically to the tooth structure
Study NCT05597592 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Feasability of a personalised physical rehabilitation program at home
Description: Monitoring of the realization of a personalised physical rehabilitation program at home by patients with neuromuscular and neurodegenrative disease
Study NCT04543188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07284890
Description: PF-07284890 will be administered orally, daily for 21 consecutive days (21-day cycle)
Study NCT05157139 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral Capsule
Description: Oral Capsule of vanillin \& wheat germ oil
Study NCT04964596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: colonoscopy
Description: colonoscopy
Study NCT04964596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: FIT test
Description: faecal immunochemical test
Study NCT04964596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: CT colonography
Description: noninvasive medical imaging technique that uses computed tomography to visualize the interior of the colon and rectum especially to screen for polyps or cancerous growths
Study NCT06583785 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Black rice (Intervention)
Description: 210 g of cooked black rice
Study NCT06583785 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Black rice (Intervention)
Description: 210 g of cooked black rice
Study NCT04778189 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: while patients in group( NS ) will receive 500-mL normal saline IV in 5-10 minutes, after spinal anesthesia
Study NCT04778189 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: i.v dexmethasone
Description: patients in group( SD )will receive 8-mg dexamethasone IV in 500-mL normal saline after spinal anesthesia
Study NCT06583785 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Brown rice (Control)
Description: 210 g of cooked brown rice
Study NCT06583785 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Brown rice (Control)
Description: 210 g of cooked brown rice
Study NCT05534594 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-PSMA-1007
Description: As explained under 'Arms'.
Study NCT06583772 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: VR-based 9-hole peg test
Description: The volunteers will first undergo a physical 9-hole peg test. After the physical test is completed, the VR-based 9-hole peg test will be performed.
Study NCT04723940 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bactrim
Description: Bactrim will be given for 6 weeks to treat joint infection
Study NCT05094908 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Arnica Tincture
Description: Arnika tincture is a topical plant-based preparation legally authorized in Colombia and in the countries of the European community, the product of this study is Arnika tinktur Gehrlicher (5249), manufactured by Gehrlicher Pharmazeutische Extrakte GmbH, Germany. According to the European Pharmacopoeia, the solution is a 70% hydroethanolic tincture prepared from the flowers of A. montana L, and composed at least 0.04% of sesquiterpene lactones. Arnica tincture will be applied topically by each participant on all lesions until day 30 or 45, depending on the regimen to be evaluated.
Study NCT04723940 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cefadroxil
Description: Cefadroxil will be given for 6 weeks to treat joint infection
Study NCT04723940 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Doxycycline Hcl
Description: Doxycycline HCl will given for 6 weeks to treat joint infection
Study NCT04723940 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clindamycin
Description: Clindamycin will given for 6 weeks to treat joint infection
Study NCT05567055 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capmatinib
Description: Capmatinib is a medication for the treatment of metastatic non-small cell lung cancer tumors that have a mutation that leads to the exon 14 skipping of the MET gene, which codes for the membrane receptor HGFR
Study NCT05543941 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: XPERIENCE Advanced Surgical Irrigation
Description: The patient will undergo THA, TKA, or HR with irrigation of the deep wound prior to fascial closure consisting of XPERIENCE Advanced Surgical Irrigation (XP). XP solution will be applied prior to fascial closure and left to soak for up to 3 minutes. Remaining product will be suctioned away throughout the procedure. No rinsing should take place after irrigation and surgical site will be closed according to site standard operating procedures.
Study NCT04543188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Binimetinib
Description: Binimetinib will be administered together with PF-07284890 orally, 45mg twice daily
Study NCT06205459 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: deep marginal acquisition using thermacut bur
Description: thermacut bur is a tool which doesn't contain any abrasives so it is much safer on the root surface of both prepared and adjacent teeth, and yields better treatment outcome in cases when exposing deep margins is needed.
Study NCT06205459 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: deep marginal acquisition using thermacut bur
Description: thermacut bur is a tool which doesn't contain any abrasives so it is much safer on the root surface of both prepared and adjacent teeth, and yields better treatment outcome in cases when exposing deep margins is needed.
Study NCT04920305 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Phosphatidylserine
Description: subjects in the treatment group oral the PS (600mg/d, q.d.) for 6 months.
Study NCT04920305 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Bean powder
Description: Subjects in the control group were given a placebo, which was the same shape of bean powder(600mg/d, q.d.).
Study NCT06088511 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: e-Health System with nutritional advice
Description: A 12-week intervention consisting of a 4-weekly group-based, face-to-face supervised sessions, and an 8-week self-management phase will be arranged to the experimental group. The features of the System will be introduced to the users and their family members in the first two face-to-face sessions. The users and their family members will then be able to start using the System with the mobile app. In the other two sessions, all participants in the experimental group will learn how to accurately complete their dietary records in the e-Health System and will be provided with nutritional advice.~For the 8-week self-management phase, the participants will be recommended to follow the lifestyle interventions to relieve their problems related to sarcopenia. The participants are required to fill in their dietary record in the e-Health System every day, and will be provided with nutritional advice to improve high-quality protein and leucine intake, which is essential for muscle building.
Study NCT05501743 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intra-articular injection of microfat and PRP
Description: The treatment by intra-articular injection of autologous microfat and PRP will be performed during a half-day outpatient stay in the hand and limb repair surgery department at the Hôpital de la Timone. The total duration of the procedure is approximately 4 hours and includes 2 surgical times performed in the operating room and an intermediate waiting time for the patient in an outpatient room during the preparation of the experimental products.
Study NCT05501743 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Total denervation of the wrist
Description: The surgical treatment by total denervation of the wrist will be performed during a one-day outpatient stay in the hand and limb surgery department at the Hôpital de la Timone. It will be performed under loco-regional anesthesia by axillary plexus block.
Study NCT06012110 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical stimulation
Description: While participants are supine with a pillow placed below the knees for comfort, one 30-minute transcutaneous electrical stimulation session will be performed at a frequency of 50 Hz, pulse width of 400 microseconds and individualized amplitude will be completed.
Study NCT04543188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Midazolam will be administered 7 days before start of study drug, on Cycle 1 Day 1, and on Cycle 1 Day 15
Study NCT04794465 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Colorectal cancer screening
Description: Patients with IBP diagnosed during the colorectal cancer screening
Study NCT05624814 — intervention group
Intervention type: DEVICE
Intervention: Spinal Cord Stimulation
Description: Spinal Cord Stimulation consists of the transcutaneous or surgical implantation of different types of electrodes in the epidural space; electrodes are then connected to an Implanted Pulse Generator that generates stimulating currents.
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: Intervention instruction outlined in protocol
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposomal Irinotecan (nal-IRI)
Description: Intervention instruction outlined in protocol
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5 Fluorouracil (5FU)
Description: Per standard of care
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin (LV)
Description: Per standard of care
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine (GEM)
Description: Per standard of care
Study NCT05251038 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: Per standard of care
Study NCT05683015 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Venapuncture
Description: Blood samples will be collected to determine the serum trough levels and anti-drug antibodies of tildrakizumab.
Study NCT05683015 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Patient questionnaires
Description: The study participants will complete the Dermatology Quality of Life (DLQI) and EQ-5D-5L questionnaire at each study visit.
Study NCT05543941 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dilute Betadine
Description: The patient will undergo THA, HR or TKA with irrigation of the deep wound prior to fascial closure consisting of Dilute Betadine (DB). DB concentration will be standardized at 0.3% povidone-iodine. DB will be prepared by combining 30 mL of sterile 10% povidone-iodine (from a sterile catheter pack) with 1 L of 0.9% saline in a sterile splash basin. Solution will be left to soak for up to 3 minutes and remaining povidone-iodine solution will be suctioned away. Area will then be rinsed with 1L of normal saline. Surgical site will be closed according to site standard operating procedures.
Study NCT05546671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Hand grip strength measurement
Description: Preoperative hand grip strength will be measured in kilograms using a digital hand dynamometer (Baseline Smedley Digital Hand Dynamometer, Model 12-0286, Baseline Evaluation Instruments, China). Participants will be instructed to grip the hand dynamometer for 5 seconds with their dominant hand 3 times. They will be allowed to rest for 20 second between each grip. The highest measurement of 3 attempts will be recorded. Participants will be categorized as strong grippers or weak grippers according to Fried criteria as previously defined by Linda P. Fried and colleagues. A weak grip will be defined as follows:~For men:~BMI ≤24: hand grip strength ≤29 kg; BMI =24.1 to 28: hand grip strength ≤30 kg; BMI >28: hand grip strength ≤32 kg~For women:~BMI ≤23: hand grip strength ≤17 kg; BMI =23.1 to 26: hand grip strength ≤17.3 kg; BMI =26.1 to 29: hand grip strength ≤18 kg; BMI >29: hand grip strength ≤21 kg
Study NCT05124379 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Hemoclin Gel
Description: Non sterile gel for intra-rectal use
Study NCT06071442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vemircopan
Description: Participants will receive oral tablets of Vemircopan.
Study NCT06071442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin
Description: Participants will receive oral coated tablets of Rosuvastatin.
Study NCT06071442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Participants will receive oral film-coated tablets of Metformin.
Study NCT06071442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levonorgestrel / Ethinyl Estradiol
Description: Participants will receive oral tablets of Levonorgestrel/ Ethinyl Estradiol.
Study NCT06071442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbamazepine
Description: Participants will receive oral chewable tablets of Carbamazepine.
Study NCT05533931 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistive Breathing Training group
Description: The patients performed two sessions each of 15 minutes session of resistive breathing for four days a week for six weeks using an inspiratory resistive device. Ask patient to take long slow inspirations while breathing through the resistive device
Study NCT05533931 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: inspiratory hold technique
Description: With the patient in a comfortable position such as side lying or reclined, the therapist may assist the patient by placing both hands on abdominal area to provide proprioceptive feedback. Then in a relaxed tone of voice therapist instructs the patient to sniff quickly through the nose three times with slow, relaxed exhalations
Study NCT05424679 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Safety Planning Intervention
Description: The Safety Planning Intervention is a brief intervention that directly targets suicide risk with demonstrated efficacy and is a recommended best practice for suicide prevention. The intervention aims to provide participants with an individualized set of steps that can be used progressively to both reduce risk and maintain safety when under particular stress. It also includes a series of brief telephone calls to revise the safety plan and facilitate connections to care. The study team will adapt the intervention to target a larger range of mental health distress.