AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05172310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI-46
Description: * \[68Ga\] Ga-FAPI-46 Solution for Injection is manufactured at the Karolinska University Hospital Radiopharmacy facilities, for imaging studies with Positron Emission Tomography (PET).~* It is a radiolabelled Fibroblast Activation Protein Inhibitor (FAPI) used for PET of a number of different cancer entities.~* Depending on the labelling yield 50 - 370 megabecquerel (MBq) of \[68Ga\] Ga-FAPI-46 Solution for Injection will be administered intravenously 60 minutes prior to whole-body PET image acquisition.
Study NCT05172310 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 68Ga-FAPI-46
Description: * \[68Ga\] Ga-FAPI-46 Solution for Injection is manufactured at the Karolinska University Hospital Radiopharmacy facilities, for imaging studies with Positron Emission Tomography (PET).~* It is a radiolabelled Fibroblast Activation Protein Inhibitor (FAPI) used for PET of a number of different cancer entities.~* Depending on the labelling yield 50 - 370 megabecquerel (MBq) of \[68Ga\] Ga-FAPI-46 Solution for Injection will be administered intravenously 60 minutes prior to whole-body PET image acquisition.
Study NCT05172310 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PET/CT
Description: * Combined PET and computed tomography (CT) imaging with 68Ga-FAPI-46 will be performed using the same protocol on a Biograph 6 PET/CT scanner (Siemens, Erlangen, Germany) and General Electrics (GE) Discovery 710, Milwaukee, Wisconsin, USA at the Department of Nuclear Medicine, Karolinska Huddinge within 2 weeks before surgery.~* PET/CT imaging will be performed in dynamic mode at one bed position centered over the primary tumor for 45 minutes.~* At 60 minutes post injection, a whole-body PET will be acquired.
Study NCT05172310 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PET/CT
Description: * Combined PET and computed tomography (CT) imaging with 68Ga-FAPI-46 will be performed using the same protocol on a Biograph 6 PET/CT scanner (Siemens, Erlangen, Germany) and General Electrics (GE) Discovery 710, Milwaukee, Wisconsin, USA at the Department of Nuclear Medicine, Karolinska Huddinge within 2 weeks before surgery.~* PET/CT imaging will be performed in dynamic mode at one bed position centered over the primary tumor for 45 minutes.~* At 60 minutes post injection, a whole-body PET will be acquired.
Study NCT05640635 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ventilator weaning first
Description: Ventilator weaning initiated and completed before start of ECMO weaning.
Study NCT05640635 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ECMO weaning first
Description: ECMO weaning initiated and completed before start of ventilator weaning.
Study NCT06500845 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bevel marginal design endocrown for endodontically treated teeth
Description: Bevel marginal design will be prepared for endodontically treated teeth and restores with Peek endocrown
Study NCT06500845 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Butt marginal design endocrown for endodontically treated teeth
Description: Butt marginal design will be prepared for endodontically treated teeth and restores with Peek endocrown
Study NCT04750239 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivatrotamab
Description: Anti GD2×CD3 monoclonal bi-specific antibody
Study NCT04205539 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: This medication will be administered sublingually using an LMA Intranasal Mucosal Atomization Device, which allows the medication to be administered in the form of a spray. Patients will be instructed to keep the medication in their mouth for about 2 minutes, or until fully absorbed. Pulse oximetry and blood pressure will be monitored throughout the duration of treatment. After the subject is asleep, the second DTI scan will be done.
Study NCT05213663 — intervention group
Intervention type: OTHER
Intervention: assessment
Description: To examine the awareness of parents of Cerebral Palsy children about the disease, physiotherapy and rehabilitation.
Study NCT05210608 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Working Memory Training (Active Intervention) + Behavioral Intervention
Description: Participants will be randomized to complete 10 sessions of a Working Memory Training. All participants will receive behavioral activation (a behavioral intervention for smoking cessation) and nicotine patches.
Study NCT05210608 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Training (CT) + Behavioral Intervention
Description: Participants will be randomized to complete 10 sessions of a Control Condition Memory Training. All participants will receive behavioral activation (a behavioral intervention for smoking cessation) and nicotine patches.
Study NCT05411653 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual reality training with motor imagery
Description: comprised of 30 minutes, VRT (15 minutes) and MI (15 minutes) daily for 3 days respectively. Five Xbox Kinect gaming will be selected and explained to the patients for the virtual training session and additional 15 minutes will be given to them for practice. The games consists of 20,000 water leaks, river rush, reflex ridge, soccer and football for the patients.
Study NCT05411653 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy
Description: range of motion exercises, muscle strengthening, functional training, balance training, and gait training. The specific tasks will be selected by the therapist based on the requirement of each patient. It will be performed for 30 minutes for 3 days a week for 6 weeks
Study NCT04968951 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metronidazole
Description: Antibiotic treatment - 250 mg every 6 hrs for 5 days
Study NCT04968951 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo treatment
Study NCT04968951 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: Antibiotic treatment - 125 mg every 6 hrs for 5 days
Study NCT04968951 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Fecal Microbiota Transplantation
Description: Encapsulated biologically active human fecal material (donor stool) is provided in capsule form. The fecal material is homogenized with sterile saline, then pelleted and re-suspended in sterile saline/40% glycerol. Participants will receive 15 FMT capsules per day for 3 consecutive days. Capsule are to be swallowed under direct supervision.
Study NCT04968951 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Fecal Microbiota Transplantation
Description: Encapsulated biologically active human fecal material (donor stool) is provided in capsule form. The fecal material is homogenized with sterile saline, then pelleted and re-suspended in sterile saline/40% glycerol. Participants will receive 15 FMT capsules per day for 3 consecutive days. Capsule are to be swallowed under direct supervision.
Study NCT05008380 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: prone positioning
Description: 3-6 hours of prone-positioning twice a day
Study NCT06353932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: keeping the endotracheal tube cuff pressure within a certain range
Description: The endotracheal tube cuff pressures of the study group patients were kept within the range of 20-25 cm H2O.
Study NCT05706285 — intervention group
Intervention type: PROCEDURE
Intervention: Regional Block Comparison
Description: Comparing postoperative pain and opioid consumption in groups
Study NCT06539650 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Fractal Paced
Description: The intervention consists in a single session of metronome paced strength training composed by 4 sets of 15 repetitions at 65% of the one-repetition maximal (1RM) in single leg extension machine, synchronizing each repetition with fractal external cues presented by a visual metronome. The rest between sets will be set at 2 minutes of rest between sets.
Study NCT06539650 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Isochronus Paced
Description: The intervention consists in a single session of metronome paced strength training composed by 4 sets of 15 repetitions at 65% of the one-repetition maximal (1RM) in single leg extension machine, synchronizing each repetition with isochronus external cues presented by a visual metronome. The rest between sets will be set at 2 minutes of rest between sets.
Study NCT06539650 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Self Paced
Description: The intervention consists in a single session of strength training composed by 4 sets of 15 repetitions at 65% of the one-repetition maximal (1RM) in single leg extension machine, at at participants' own self pace (with no metronome). The rest between sets will be set at 2 minutes of rest between sets.
Study NCT05208892 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SZMN block
Description: Suprazygomatic Maxillary Nerve (SZMN) Blocks bilaterally
Study NCT05208892 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SZMN block with Dexmedetomidine
Description: Suprazygomatic Maxillary Nerve (SZMN) Blocks with local anesthetic and Dexmedetomidine bilaterally
Study NCT05039541 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Alio Device
Description: Subjects will wear the Alio device over their vasculature.
Study NCT05885685 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nabilone Oral Capsule
Description: Each oral capsule contains a 0.25 mg dose of nabilone. Participants begin by taking 1 capsule at night then 1 capsule in the morning and 1 at night for the next 2 days. On the 4th day, the dose is doubled. On the 6th day, the dose is doubled again.
Study NCT04884022 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Miniplates in mandibular symphysis & infrazygomatic
Description: Fixed functional appliance (pushing orthopedic force) in conjunction with direct skeletal anchorage
Study NCT04884022 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Miniplates in external oblique ridge & anterior maxillary region
Description: Coil spring (pulling orthopedic force) in conjunction with direct skeletal anchorage
Study NCT05348928 — intervention group
Intervention type: DEVICE
Intervention: Continuous glucose monitoring device
Description: Continuous glucose monitoring device
Study NCT05348928 — intervention group
Intervention type: OTHER
Intervention: Laboratory plasma glucose concentration determination
Description: Laboratory plasma glucose concentration determination
Study NCT04498858 — intervention group
Intervention type: OTHER
Intervention: Patient interview
Description: Patient will be interviewed :~* tobacco consumption~* reported question asked by the dentist about his/her tobacco consumption~* presence and nature of reported advices given by the dentist~* presence and nature of actions proposed by dentists for patients reporting tobacco consumption, including prescription of NRT~* presence and nature of the actions carried out or envisaged by these patients, including - smoking cessation~* contact with the general practioner~* Fagerstrom score (2 questions)~* demographic variables, age, sex, level of education~* satisfaction
Study NCT05197868 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation with traditional laryngoscope
Description: Participants will be invited to intubate the mannequin with a traditional laryngoscope
Study NCT05197868 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intubation with a straight blade video laryngoscope
Description: Intubation with a straight blade video laryngoscope
Study NCT05197868 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intubation with a hyper-angulated video laryngoscope
Description: Participants will be asked to intubate the mannequin with a hyper-angulated video laryngoscope
Study NCT05734781 — intervention group
Intervention type: OTHER
Intervention: Not Application as this is a qualitative study
Description: Not Application as this is a qualitative study
Study NCT05014282 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine patch
Description: Participants will be provided with a 10-week supply of nicotine patches
Study NCT05014282 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine patch
Description: Participants will be provided with a 10-week supply of nicotine patches
Study NCT05014282 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Counseling
Description: Phone counseling with the state tobacco quitline.
Study NCT05014282 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine lozenge
Description: Participants will be provided with a 10-week supply of nicotine lozenges
Study NCT05704296 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Y-composite grafting
Description: Saphenous vein is used as a Y-composite graft during coronary artery bypass grafting
Study NCT05704296 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Aortocoronary grafting
Description: Saphenous vein is used as an aortocoronary graft during coronary artery bypass grafting
Study NCT05014282 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine lozenge
Description: Participants will be provided with a 10-week supply of nicotine lozenges
Study NCT05014282 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Smartphone-delivered automated treatment
Description: An interactive smartphone-based intervention that comprises content delivered via audio/video clips and text content automatically each week to the participant
Study NCT04404400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Investigational products administration
Description: Investigational products include:~* Hydrocortisone hemisuccinate 50 mg: one intravenous injection every 6 hours, and~* 9 alpha fludrocortisone 50 μg: one tablet per day via a nasogastric tube.~All treatments will be stopped after 7 days or until the patient has left the intensive care unit (whichever occurs first) without tapering off.
Study NCT04404400 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo administration
Description: Placebos for hydrocortisone and for fludrocortisone, administered in same manner as the active drugs in the interventional arm, for 7 days.
Study NCT06508996 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Xpert HCV
Description: Detection of HCV RNA by Xpert HCV test
Study NCT05539911 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Fentanyl
Description: 50 mic fentanyl added as an adjuvant
Study NCT05539911 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: 50 mic fentanyl added as an adjuvant
Study NCT05987150 — intervention group
Intervention type: RADIATION
Intervention: Variation in anisotropy of the Spinal Cord using diffusion tensor imaging
Description: All examinations were performed on a 3.0-T MRI machine with a 12-channel spine special coil (Ingenia CX, Philips Healthcare, Best, the Netherlands). The multi-sequence MRI protocol included conventional T1-weighted (sag \& tra), T2-weighted (sag \& tra), and DTI sequence.
Study NCT05158257 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: balloon and Stent
Description: balloon dilatation combined stent angioplasty
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Western Ontario and McMaster University Osteoarthritis Index (WOMAC)
Description: 1. WOMAC is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self-administered questionnaire consisting of 24 items divided into 3 subscales
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Western Ontario and McMaster University Osteoarthritis Index (WOMAC)
Description: 1. WOMAC is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self-administered questionnaire consisting of 24 items divided into 3 subscales
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Visual Analogue Scale (VAS)
Description: 2. VAS is one of the pain rating scales used in epidemiologic and clinical research to measure the intensity or frequency of various symptoms.
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Visual Analogue Scale (VAS)
Description: 2. VAS is one of the pain rating scales used in epidemiologic and clinical research to measure the intensity or frequency of various symptoms.
Study NCT06570408 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: PLACEBO_COMPARATOR
Intervention: Kellgren Lawrence Grading Scale (KL score)
Description: 3. KL score is the most widely used clinical tool for the radiographic diagnosis of OA.Each radiograph was assigned a grade from 0 to 4,
Study NCT06570408 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Kellgren Lawrence Grading Scale (KL score)
Description: 3. KL score is the most widely used clinical tool for the radiographic diagnosis of OA.Each radiograph was assigned a grade from 0 to 4,
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Quality of Life Questionnaires and Assessments:
Description: 4. Quality of Life Questionnaires and Assessments: include quality of life, intestinal tract, conscious assessment of pain relief.etc.
Study NCT06570408 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Quality of Life Questionnaires and Assessments:
Description: 4. Quality of Life Questionnaires and Assessments: include quality of life, intestinal tract, conscious assessment of pain relief.etc.
Study NCT05574400 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dextrose Water
Description: Dextrose 5% in water
Study NCT05574400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine citrate
Description: Low-dose caffeine citrate (1.5 mg/kg)
Study NCT05574400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine citrate
Description: High-dose Caffeine citrate (3 mg/kg)
Study NCT05158257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: endovascular debulking and DCB
Description: endovascular debulking combined drug-coated balloon
Study NCT06052033 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CO2
Description: CO2 laser treatment is a surgical procedure that employs a high-powered carbon dioxide laser beam to precisely ablate cervical lesions. The laser is applied with a depth of 7-10mm and a width of 3-5mm beyond the lesion area in a single session. This intervention aims to address persistent low-grade cervical lesions associated with high-risk HPV infection.
Study NCT06052033 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: CO2
Description: CO2 laser treatment is a surgical procedure that employs a high-powered carbon dioxide laser beam to precisely ablate cervical lesions. The laser is applied with a depth of 7-10mm and a width of 3-5mm beyond the lesion area in a single session. This intervention aims to address persistent low-grade cervical lesions associated with high-risk HPV infection.
Study NCT05144256 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitapivat
Description: Tablets or granules
Study NCT06126939 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational training based on the Denver model
Description: In addition to routine health guidance, one-to-one parent classes were conducted to guide parents to interact with children once a week for 1h each time; A group leader was assigned to supervise the formulation of the intervention plan and ensure the quality of the intervention. The intervention lasted for 3 months
Study NCT05643833 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention
Study NCT04762251 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time-restricted eating
Description: Time restricted eating for a self-selected 9 hour window per day
Study NCT04762251 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Current Best Practice
Description: Best practice guidelines to improve diet quality
Study NCT06267339 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial random noise stimulation
Description: This intervention will give children tRNS during reaching or grasping repetitive movements.
Study NCT06267339 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham stimulation
Description: This intervention will give children sham stimulation during reaching or grasping repetitive movements.
Study NCT05644106 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: personal sound amplification product, hearing aid
Description: the device for hearing gain in sensorineural hearing loss
Study NCT04556045 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise therapy
Description: The exercise therapy intervention will last 4 weeks. Each participant assigned to this intervention will receive a personalized ET regimen, including in-person, supervised exercise sessions; other activities to be followed at home. Participants will exercise between one and seven times per week depending on their tolerance to the treatment and exercise program.
Study NCT06626854 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: RF-PNS
Description: Noninvasive peripheral nerve stimulator using interferential multi source radio frequency
Study NCT05144256 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitapivat-matching placebo
Description: Tablets or granules
Study NCT05144256 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Mitapivat-matching placebo
Description: Tablets or granules
Study NCT04660929 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CT-0508
Description: anti-HER2 CAR macrophages
Study NCT05344118 — intervention group
Intervention type: OTHER
Intervention: Survey
Description: REDCap survey