AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04591340 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: dietary advice, oral nutritional supplement, supplementary parenteral nutrition or total parenteral nutrition
Description: All HSCT(hematopoietic stem cell transplantation) patients should be accepted dietary advice or oral nutritional supplement, if their energy intake will not reach 60% of the goal level during the transplanting, then supplementary parenteral nutrition or total parenteral nutrition.
Study NCT06436170 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: OCTA
Description: OCTA is a non invasive diagnostic technique to visualize RPC
Study NCT05796141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dyadic Action Planning
Description: Participants will develop dyadic action plans together.
Study NCT04866355 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lumbar spine manipulation
Description: Lumbar spine manipulation
Study NCT04866355 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Lumbar spine manipulation
Description: Lumbar spine manipulation
Study NCT04866355 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyoscine and Ibuprofen
Description: hyoscine (20 mg) and ibuprofen (400 mg) administered by oral via.
Study NCT05796141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Joint Feedback
Description: Participants will see data on their partner's progress, in addition to their own weight and behavioral data.
Study NCT04628949 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: aScope™ Duodeno endoscope and aBox™ Duodeno
Description: The aScope™ Duodeno endoscope is a sterile single-use disposable duodenoscope indicated for endoscopic retrograde cholangiopancreatography (ERCP) procedures.The aScope™ Duodeno endoscope is designed to be used with aBox Duodeno, endoscopic accessories and other ancillary equipment for ERCP procedures.~The aBox Duodeno is the console that is necessary for processing the endoscope camera´s video image, regarding the remote switches and output video and recorder data. The aBox Duodeno is designed to be used with the aScope™ Duodeno endoscope.
Study NCT04512638 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotics
Description: Antibiotic treatment is the same in all groups.~Monotherapy for 4 weeks with:~No penicillin contra-indication~* Amoxicillin-clavulanate 875mg tid PO Penicillin contra-indication or intolerance~* Clindamycin 300mg tid PO~After 4 weeks patients will be switched to consolidation antibiotics:~No penicillin contra-indication~* Amoxicillin 1g bid PO Penicillin contra-indication or intolerance~* Clindamycin 300mg tid PO~Antibiotic treatment can be discontinued after 4 weeks when the MRONJ lesions has healed.
Study NCT04512638 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Antibiotic treatment is the same in all groups.~Monotherapy for 4 weeks with:~No penicillin contra-indication~* Amoxicillin-clavulanate 875mg tid PO Penicillin contra-indication or intolerance~* Clindamycin 300mg tid PO~After 4 weeks patients will be switched to consolidation antibiotics:~No penicillin contra-indication~* Amoxicillin 1g bid PO Penicillin contra-indication or intolerance~* Clindamycin 300mg tid PO~Antibiotic treatment can be discontinued after 4 weeks when the MRONJ lesions has healed.
Study NCT06237595 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vagus nerve stimulation
Description: Electrical stimulation of the vagus nerve.
Study NCT06237595 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Medical treatment
Description: Medical treatment for fibromyalgia patients
Study NCT06237595 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Combined vagus nerve stimulation and medical treatment
Description: Combination of the two interventions
Study NCT04512638 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chlorhexidine mouthwash
Description: Patients in all treatment groups will be prescribed aqueous chlorhexidine 0.12% tid rinse for 2 weeks, with subsequent switch to 0.05% for the duration of the study or until healing of the MRONJ lesion has occurred.
Study NCT04512638 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chlorhexidine mouthwash
Description: Patients in all treatment groups will be prescribed aqueous chlorhexidine 0.12% tid rinse for 2 weeks, with subsequent switch to 0.05% for the duration of the study or until healing of the MRONJ lesion has occurred.
Study NCT04512638 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Minimally invasive surgery with LPRF
Description: Minimally-invasive surgical treatment, including sequestrectomy, debridement of soft tissue, and application of LPRF membranes before tension-free wound closure is obtained. Marginal resection of all necrotic bone is not part of this treatment strategy.
Study NCT04512638 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical resection
Description: Primary surgical management consisting of the removal of the necrotic bone without excessive resection of healthy bone. Buccal mucoperiosteal flaps will be used to achieve a tension-free mucosal coverage.
Study NCT05714943 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DigiKnowIt News: Teen
Description: Participants will interact with a multimedia educational website that will teach them about pediatric clinical trials, including topics such as participant rights and safety and different types of procedures used in trials, and will provide strategies for parent-teen shared decision-making about clinical trials.
Study NCT05951387 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dexmedetomidine plus ketamine
Description: titrating the dose of dexmedetomidine mixed with ketamine (staring dose 0.5ug/kg/hr, 0.5mg/kg/hr respectively)to achieve full sedation
Study NCT05235802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Magnetic Resonance Imaging (MRI) (including functional MRI)
Description: Patients will undergo magnetic resonance imaging including the following protocols:~* 3D T1w MPRAGE~* 3D T2w FLAIR SPACE~* 3D T2w SPACE~* 3D T1w PSIR (cortical visualization)~* 2D synthetic MRI (quantitative T1, T2, PD and myelin quantification)~* Resting-state fMRI (6 min, human connectome protocol, 2 mm iso)~* 3D SWI~* DWI b1000 32 directions and b3000 64 directions.
Study NCT05235802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood sampling (serum/plasma preparation)
Description: Blood will be screened for genetic modifications. Serum will be analyzed for auto-antibodies and other inflammatory and neurodegenerative biomarkers.
Study NCT05235802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cerebrospinal fluid (CSF)
Description: CSF will be analyzed for inflammatory and neurodegenerative biomarkers.
Study NCT05235802 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical assessments / questionnaires
Description: * Glasgow Outcome Scale Extended (functional outcome)~* Short-Form 36 (quality of life),~* EQ-5D (quality of life),~* Mini-Mental State Extended (MMSE) (mental state assessment).~* Barthel Index (daily living disabilities),~* Montgomery-Åsberg Depression Score (MADRS-S) (level of depression)~* Fatigue Severity Scale (FSS) (level of fatigue)~Other than that, neurological assessments focusing on the Unified Parkinson's Disease Rating Scale (UPDRS) will be performed.
Study NCT05105893 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Dates group
Description: Seven dates to be provided to patients
Study NCT05796141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Autonomy Support Training
Description: Participants will receive training in how to create an autonomy supportive environment within their marriage/partnership.
Study NCT05188677 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Candidate vaccine, SCB-2019
Description: a recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19; intramuscular injection
Study NCT05188677 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty Vaccine
Description: intramuscular injection
Study NCT05188677 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Vaxzevria Vaccine
Description: intramuscular injection
Study NCT05188677 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: CoronaVac Vaccine
Description: intramuscular injection
Study NCT06329609 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Airvo 3 with respiratory rate algorithm
Description: Airvo 3 with respiratory rate algorithm is an active humidification system used to deliver high flow respiratory gases (air and/or oxygen) and monitor respiratory rate
Study NCT05446259 — intervention group
Intervention type: OTHER
Intervention: Standard clinical care procedures and outcome measurements.
Description: Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.
Study NCT05489614 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olpasiran
Description: Participants will receive olpasiran by subcutaneous (SC) injection.
Study NCT04402294 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: The investigators will create individualized TMS targets using deep learning methods on task and resting fMRI data to target working memory augmentation. The individualized target will be stimulated in a subsequent fMRI scan involving working memory task performance interleaved with repetitive TMS (rTMS) delivered at a variety of stimulation frequencies. Based on activation readouts in response to rTMS, an optimal and sub-optimal brain state frequency to impact working memory performance will be selected for each participant. Participants will receive rTMS at each frequency separately for three days (six days total), with the order of frequency randomly assigned and counterbalanced. Following each three day protocol, another fMRI working memory readout will be conducted to support the targeting and frequency selection algorithms.
Study NCT05053412 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Helio Liver Test
Description: A Helio Liver Test is used as the basis of performance evaluation for specificity and sensitivity for all patients enrolled in the study.
Study NCT05796141 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home Environment Modifications
Description: Participants will be trained in how to structure their home environment to support health behavior.
Study NCT05057000 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: aerobic exercises + Diet
Description: Frequency 5-6 days per week Intensity To perform moderate intensity for weight-bearing aerobic exercise Time Goal of 20-30 min per session of moderate-intensity aerobic activity per week
Study NCT05057000 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: diet proram
Description: diet program for anorexic adolescent girls
Study NCT06550466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breakfast only
Description: Participants will attend a breakfast-only arm without the exercise protocol.
Study NCT04193228 — intervention group
Intervention type: DEVICE
Intervention: Carbon Fibre Ankle Foot Orthosis
Description: Off teh shelf carbon fibre ankle foot orthoses worn bilaterally
Study NCT05951387 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: starting intravenous infusion with dexmedetomidine starting at dose 0.5ug/kg//hr and titrate the dose to achieve full sedation
Study NCT04193228 — intervention group
Intervention type: BEHAVIORAL
Intervention: Exercise
Description: Ankle muscle strength training
Study NCT05326932 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mechanical thrombectomy
Description: Subjects in intervention group will receive MT as soon as possible. Investigators and clinicians should strive to reduce delays of pre-surgery procedure and follow the local standard guideline of MT during the operation and perioperative period. All CFDA approved devices are allowed in this trial. Angioplasty and stent placement can be performed at the discretion of the physicians. Base on site experience, the randomization-operation start period should be within 60 minutes.
Study NCT04927611 — intervention group
Intervention type: PROCEDURE
Intervention: Biopsy, open or laparoscopic surgery
Description: Collect NEN and PDAC biopsy or surgical fresh tissue to conduct single cell sequencing or model construction.
Study NCT06550466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FAST
Description: Participants will be exercised for 90 minutes following a 12-hour overnight fast
Study NCT06550466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FED
Description: Participants will be exercised 90 minutes after a breakfast
Study NCT06013748 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR-VOICES
Description: 7-10 individual VR assisted therapy for voice-hearing session and two booster sessions, in addition to TAU.
Study NCT06013748 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Treatment as usual
Description: Treatment as usual as provided by the mental health centers
Study NCT06397508 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGMB-129
Description: Each participant will receive 3 study interventions, 1 in each intervention period
Study NCT05382403 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jada® System
Description: This is a U.S. FDA-cleared device intended for treatment of PPH when conservative management is warranted. The device is made of medical grade silicone. The distal end, which is placed in the uterus, is an elliptical loop. The circular cervical seal, just outside the external cervical os, is filled with 60 - 120 mL sterile water. Low-level vacuum (80 ± 10 mm Hg) is applied and pooled blood is evacuated from the uterus as it collapses. Once there is no bleeding, the device remains in the uterus for at least 1 hour. The suction is then disconnected, the seal emptied of water, the device left in place, and the patient monitored for an additional 30 minutes. If bleeding remains controlled, the device is removed. If bleeding is uncontrolled with the Jada® System patients will have surgical intervention with options of uterine vascular ligation, uterine compression sutures or hysterectomy.
Study NCT05382403 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard care
Description: Patients in this group will receive care according to the treatment algorithm for PPH from uterine atony at the two teaching hospitals in Ghana. Possible interventions include additional uterotonics, tranexamic acid, and condom catheter balloon uterine tamponade. If bleeding is uncontrolled, patients will have surgical intervention with options of uterine vascular ligation, uterine compression sutures or hysterectomy.
Study NCT06161779 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Surgical reconstruction
Description: submental artery island flap (SMAIF) for the reconstruction of laryngeal and hypopharyngal defects after the surgical resection of hypopharyngeal cancer
Study NCT05195723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: WP1122
Description: Oral solution
Study NCT05195723 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral solution
Study NCT01740245 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Chlorhexidine vaginal suppositories
Study NCT01740245 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polyhexamethylene biguanide vaginal suppositories
Study NCT05018377 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Racz adhesolysis
Description: adhesiolysis in failed back surgery
Study NCT05018377 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NAVI adhesolysis
Description: adhesiolysis in failed back surgery
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol continuous infusion
Description: Propofol intravenous continuous infusion for anesthetic induction and maintenance
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remifentanil
Description: Remifentanil intravenous continuous infusion for anesthetic induction and maintenance
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sevoflurane
Description: Study participants receive fentanyl 1mcg/kg and propofol 1.5\~2mg/kg for induction of general anesthesia. For maintenance of anesthesia, desflurane is used to maintain 1 age-related minimum alveolar concentration (MAC).
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Desflurane
Description: 1 age-related minimum alveolar concentration (MAC) of desflurane inhalation for anesthetic maintenance
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol bolus injection
Description: Propofol intravenous injection for anesthetic induction
Study NCT03763305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl
Description: Fentanyl intravenous injection for anesthetic induction
Study NCT04833530 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Gastric Ultrasound
Description: In the operating room, a gastric ultrasound will be performed in the supine position and the antral cross sectional area will be measured. Anesthesia will be induced in standard procedure and positive pressure will be instituted according to the standard protocol accepted in our hospital.~At the end of the procedure, the gastric ultrasound circumference will be measured again.
Study NCT05965973 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low fat diet
Description: During 3 days, subjects eat a diet low in fat (percent of total caloric intake: 15.0% from proteins; 65.0% from carbohydrates; 20.0% from fat: 4.0% from saturated fat; 10.0% from monounsaturated fat; 6.0% from polyunsaturated fat
Study NCT05965973 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High fat diet
Description: During 3 days, subjects eat a diet high in fat (percent of total caloric intake: 15.0% from proteins; 45.0% from carbohydrates; 40.0% from fat: 8.0% from saturated fat; 22.0% from monounsaturated fat; 10.0% from polyunsaturated fat
Study NCT05071976 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ICG-NIR angiography
Description: Capture NIR video of flap site beginning at time of ICG injection. At time of subjective peak intensity, capture video of flap and recipient wound bed. Measure rate of ICG egress from the global flap at 60, 120, and 180 seconds after initial dye injection from intraoperative video
Study NCT05231005 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: BNT162b2 vaccine
Description: fourth dose of the BNT162b2 vaccine (30 microgram) adminstered IM
Study NCT06623474 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: diagnosed by traditional diagnostic markers（such as AFP or CT etc.）
Description: A prospective observational cohort study to explore the advantages of lipid metabolites as diagnostic markers for hepatocellular carcinoma compared to traditional diagnostic markers for hepatocellular carcinoma (e.g., AFP, enhanced CT, etc.).
Study NCT06626464 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]MK-8189
Description: Oral administration
Study NCT06625918 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultraviolet B exposure to produce vitamin D synthesis
Description: Exposure using a UV skin care device on vitamin D production and immune response in healthy adults
Study NCT06633601 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MR-Guided Focused Ultrasound Technology
Description: MRI Guidance for use with High-intensity-focused ultrasound (HIFUS)
Study NCT06633601 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Definity Suspension for Injection
Description: Microbubble contrast agents for ultrasound
Study NCT06633874 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: TD Playing the Serious Game APSOU
Description: After parents participate in informative meetings, they proceed with written consent, SmartSpeech enrollment, and child developmental history. Then, the child may interact with the Serious Game. Typically developed (TD) children engage under the clinician's face-to-face supervision with the serious game APSOU, which assesses developmental domains, including speech, language, psychomotor, cognitive, psychoemotional, and hearing abilities. The average time for TD children to play the whole game is estimated to be 45 minutes.
Study NCT06633874 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Non-TD Playing Serious Game
Description: After parents participate in informative meetings, they proceed with written consent, SmartSpeech enrollment, and child developmental history. Then the child may interact with the serious game. Non-typically developed (non-TD) children engage under the clinician's face-to-face supervision with the serious game Apsou, which assesses developmental domains, including speech, language, psychomotor, cognitive, psychoemotional, and hearing abilities. The average time for non-TD children to play the whole game is estimated to be over an hour.
Study NCT06633705 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vaginal Cream with Applicator
Description: Vaginal Cream that contains estriol (1mg estriol in 1 g cream)
Study NCT04667286 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Prone Position (PP)
Description: Prone the patients on oxygen for at least 10 hrs a day
Study NCT04667286 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prone Position (PP)
Description: Prone the patients on oxygen for at least 10 hrs a day
Study NCT04794036 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Asynchronous telerehabilitation programme
Description: Home-based physical rehabilitation programme using a telerehabilitation platform