AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06204718 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard pelvic floor exercises
Description: Pelvic floor muscle exercises will be given as 2 separate exercises including fast and slow contractions. For fast contractions, participants will be asked to contract their pelvic floor muscles strongly, hold them contracted for 5 seconds, and then relax them. For slow contractions, participants will be asked to gradually contract the pelvic floor muscles, hold them at maximum contraction for 5 seconds, and relax them gradually. Participants will be asked to perform 10 slow contractions after every 10 fast contractions. The aim is to train strength, coordination, endurance, and symmetry of pelvic floor muscles, motor learning and control, dynamic lumbopelvic stability, pelvic floor, and abdominal co-contraction. Every day, 10 fast, and 10 slow contractions with a total of 20 repetitions will be applied without changing the number by modifying the exercises every week. It will be applied for a total of 12 weeks.
Study NCT06204718 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Involuntary reflexive pelvic floor exercises
Description: Reflexive exercises (jump, squat jump, etc.) with 20 repetitions per day will be applied to the participants for 12 weeks with modifications every week.
Study NCT06471816 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dialogue Based Early Detection
Description: Before the biannual parent-teacher meeting, both the kindergarten teacher and the parents will complete the Early Worry Questionnaire containing 39 items related to development and well-being of the individual child. For each item the respondents are asked to indicate if they during the last three months have been concerned. In the parent-teacher meeting they will discuss their possible concerns and try to reach an agreement on how to evaluate the child. If necessary, possible supportive interventions or further assessments locally in the kindergarten or in the public services will be decided.
Study NCT06471816 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional parent-teacher meeting
Description: This is an annual or biannual meeting that is prepared by the kindergarten teacher where (s)he reports on the child's appearance / behaviour and possible challenges as to development and behaviour from an educationalist's view. There are no common templates for the agenda of such meetings, however, usually the kindergarten teacher's perspective and opinion will dominate.
Study NCT06320028 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-Invasive Transcranial Focused Ultrasound
Description: The ultrasound will be delivered for 10 minutes per treatment session targeting to the participant's amPFC.
Study NCT04520737 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Prehabilitation
Description: The prehabilitation program consists of the following interventions: in-hospital high-moderate intensive exercise training, nutritional assessment and high-protein supplementation, smoking cessation, psychological support and Comprehensive Geriatric Assessment.
Study NCT05020990 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (delefilcon A)
Description: Daily disposable for one week
Study NCT05020990 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (stenfilcon A)
Description: Daily disposable for one week
Study NCT04675203 — intervention group
Intervention type: PROCEDURE
Intervention: Tooth extraction
Description: Tooth extraction
Study NCT04752137 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Indocyanine green
Description: The SPY PHI and its dye Indocyanine Green dye (ICG) is a non-invasive device that is connected to a light source tower that is already available in the hospital in the operating room under Gynecology and Obstetrics Equipment. This is a special light source lamp that allows to test for vascularity in the soft tissues intraoperatively. Previous research in animal models proved the concept that the increased vascularity in tumors can be used to use this device to improve intraoperative assessment of tumor margins during resection. Our study will help to establish a correlation between activity with the dye and histological findings. This information has the potential to help sarcoma patients by avoiding staged surgeries, decreasing hospitalization times, and decreasing the likelihood of local recurrence by improving margin quality.
Study NCT04752137 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: SPY-PHI
Description: The SPY PHI and its dye Indocyanine Green dye (ICG) is a non-invasive device that is connected to a light source tower that is already available in the hospital in the operating room under Gynecology and Obstetrics Equipment. This is a special light source lamp that allows to test for vascularity in the soft tissues intraoperatively. Previous research in animal models proved the concept that the increased vascularity in tumors can be used to use this device to improve intraoperative assessment of tumor margins during resection. Our study will help to establish a correlation between activity with the dye and histological findings. This information has the potential to help sarcoma patients by avoiding staged surgeries, decreasing hospitalization times, and decreasing the likelihood of local recurrence by improving margin quality.
Study NCT04746482 — intervention group
Intervention type: PROCEDURE
Intervention: single visit root canal retreatment
Description: cases that were subject to root canal retreatment performed in single visit
Study NCT05363293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AL 001
Description: a crystal engineered lithium-salicylate-proline lithium delivery product
Study NCT05363293 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: matching placebo formulation
Study NCT04872933 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Kidney Beam Online Platform
Description: Kidney Beam is a wellbeing digital health intervention platform that offers patients living with kidney disease a way to improve their physical activity and boost their mental health through live and on demand movement classes and expert educational videos, while remaining in their own home. Kidney Beam is led by specialist kidney professionals, including renal physiotherapists and renal counsellors, from a number of different NHS Trusts and backgrounds, as well as people living with kidney disease.
Study NCT05391425 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention planned, since it is an observational study
Study NCT06463704 — intervention group
Intervention type: OTHER
Intervention: There is no intervention
Description: There is no intervention
Study NCT04419740 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness based psychological intervention
Description: Women in the intervention group will have to use an application during 1 month. They will do meditation during 15 minutes each day.
Study NCT05135195 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-House Developed VR Platform - AMD, DR, Glaucoma
Description: Participants will conduct experiments using commercial VR headsets and controllers. Visual impairments will be systematically simulated in VR. There are three visual impairment simulations (AMD, DR, and glaucoma) at three levels of severity (mild, moderate, or severe). Symptoms' simulation tools include a gaussian blur shader, distortion shader, and a culling mask with a gray spot in the middle.
Study NCT05135195 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: In-House Developed VR Platform - Glaucoma
Description: In the second set of experiments, a multidimensional visual impairment simulation of a single pathology (glaucoma) will be used at three levels of severity (mild, moderate, or severe). The post-processing package to simulate includes glare, difficulty in light, change adaptation, ambient occlusion, visual clutter, and overall blurred effect. The shader graph package will be used to create a distortion localized on assets surfaces only.
Study NCT03886337 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Germicidal lighting
Description: Germicidal ambient lighting
Study NCT06274203 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D3
Description: Subjects within SCD as well as healthy controls, received monthly oral vitamin D3 dose, for 6 months, according to the baseline status of vitamin D as follows: sufficient (>30 ng/mL): 100,000 IU, insufficient (20-29.9 ng/mL): 150,000 IU, and deficient (\<20 ng/mL): 200,000 IU.
Study NCT05721963 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: No interventions.
Description: No interventions.
Study NCT05487781 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Tirfostina/L-Carnitina
Description: Estudio clínico fase 1 para describir la seguridad biológica y la farmacocinética de la tirfostina AG-17
Study NCT05489055 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Iopamidol
Description: A contrast bolus of iopamidol-370 (370 mg I/ml) (iopamidol injection; Consun Pharmaceutical, China) was injected at a ﬂow rate of 4.5-6 mL/s through an 18-20-gauge intravenous antecubital catheter by using a power injector (Ulrich, Germany). The total dose of iopamidol-370 was approximately 0.9 ml /kg body weight.
Study NCT05489055 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Iopamidol
Description: A contrast bolus of iopamidol-370 (370 mg I/ml) (iopamidol injection; Consun Pharmaceutical, China) was injected at a ﬂow rate of 4.5-6 mL/s through an 18-20-gauge intravenous antecubital catheter by using a power injector (Ulrich, Germany). The total dose of iopamidol-370 was approximately 0.9 ml /kg body weight.
Study NCT06475950 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kid'EM app experimental group
Description: In the Kid'EM app experimental group arm, only the application used differs. Visits are organized in the same way as in the controle app arm.~Visit 0 (Inclusion) + Visit 1 (V1) : Physical visit~Children are included in the study by the investigator, formalized by signing a consent form.~Parents fill in questionnaires~Visit 2 (when 1st objective is set):~Telephone interview to assess performance and satisfaction levels after the first goal has been set.~Visit 3 (when setting the 2nd goal):~Telephone interview to assess performance and satisfaction levels after the second goal has been set.~Visit 4 (week 14 - end of study): Physical visit~The questionnaires are again completed by the parents, either directly on a tablet or on paper for later input.~Visit 4 bis:~Telephone interview to assess performance and satisfaction levels after the work on the first two objectives.~Visit 5 (focus group, optional post-study visit)
Study NCT06475950 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Kid'EM app control group
Description: Use of control application without guidance for goal setting~Visit 0 (Inclusion) + Visit 1 (V1) : Physical visit~Children are included in the study by the investigator, formalized by signing a consent form.~Parents fill in questionnaires~Visit 2 (when 1st objective is set):~Telephone interview to assess performance and satisfaction levels after the first goal has been set.~Visit 3 (when setting the 2nd goal):~Telephone interview to assess performance and satisfaction levels after the second goal has been set.~Visit 4 (week 14 - end of study): Physical visit~The questionnaires are again completed by the parents, either directly on a tablet or on paper for later input.~Visit 4 bis:~Telephone interview to assess performance and satisfaction levels after the work on the first two objectives.~Visit 5 (focus group, optional post-study visit)
Study NCT06265740 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: vaginal swab
Description: Any pregnant woman attending the obstetrics department of Clermont-Ferrand University Hospital who requires a vaginal swab (VS) for her clinical situation (routine care) will be offered the study. If she accepts, the usual swab will be doubled and performed simultaneously in a single procedure using two swabs. The first swab will be sent to the laboratory and used for diagnosis. The second swab will be used for microbiota analysis.
Study NCT01929850 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Laparscopic Sleeve Gastrectomy
Description: The laparoscopic sleeve gastrectomy involves the placement of 5 trocars. A leak check may be performed at the same time by insufflating with a gastroscope with the remnant gastric section submerged in irrigation fluid and by infusing sterile methylene blue through a nasogastric tube. The staple line may be oversewn (3-0 Vicryl, Ethicon), only along the bleeding and leakage areas, or areas with the potential for such complications. A nasogastric decompression tube placed to monitor bleeding and an intraperitoneal drain was placed under an anastomotic stoma.
Study NCT01929850 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Weight Watchers Program
Description: Intensive medically supervised nutritional and exercise therapy
Study NCT01929850 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Weight Watchers Program
Description: Intensive medically supervised nutritional and exercise therapy
Study NCT04685915 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibrutinib
Description: Capsule, taken by mouth once daily
Study NCT04685915 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Copanlisib
Description: Intravenous Infusion
Study NCT04685915 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acalabrutinib
Description: Capsule, taken by mouth twice daily
Study NCT04608851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E. coli Nissle
Description: 1 ml of oral suspension containing 10 E8 CFU /ml of E. coli Nissle strain
Study NCT04608851 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo control
Description: 1 ml oral syrup consisting of Saccharum 630 mg/g and Aqua purificata 370 mg/g.
Study NCT04768231 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rifampin
Description: The target dose of 35mg/kg will be reached supplementing fixed-dose combination tablets (standard dose) with rifampin-only tablets.
Study NCT05780567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3616 capsules, Letrozole, Anastrozole, Tamoxifen
Description: TQB3616 is a novel Cyclin-dependent kinase (CDK) 4/6 inhibitor and currently being used in the treatment of a variety of malignant solid tumors.~Letrozole combined with Anastrozole and Tamoxifen is an endocrine therapy that involves adding, blocking, or removing hormones. It can be used for conditions that affect hormone levels, such as breast cancer.
Study NCT05780567 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsules, Letrozole, Anastrozole, Tamoxifen
Description: Letrozole combined with Anastrozole and Tamoxifen is an endocrine therapy that involves adding, blocking, or removing hormones. It can be used for conditions that affect hormone levels, such as breast cancer.
Study NCT06459908 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Robot Glove Hand Training
Description: Robot Assisted group will perform hand exercises with the help of robotic glove assistance for 3 times per day/ 4 times per week, 45 minutes per session for 6 consecutive weeks. Total Number of Sessions will be 72 Hours.
Study NCT06459908 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Hand Rehabilitation Exercises
Description: Conventional therapy group will perform hand exercises without the help of robotic gloves 3 times per day/ 4 times per week, 45 minute session for 6 consecutive weeks.Total number of sessions will be 72.
Study NCT06459908 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Hand Rehabilitation Exercises
Description: Conventional therapy group will perform hand exercises without the help of robotic gloves 3 times per day/ 4 times per week, 45 minute session for 6 consecutive weeks.Total number of sessions will be 72.
Study NCT05278247 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: NIRS
Description: Performance of a NIRS to monitor abdominal tissue oxygen saturation in preterm infants
Study NCT05435092 — intervention group
Intervention type: RADIATION
Intervention: 3D-reconstruction CT
Description: Three dimensional CT (3D CT):Method of surface rendition of anatomy by means of a special computer software to capture 3D bone models used to improve the outcomes of Total Knee Arthroplasty (TKA).
Study NCT05082220 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinae plane block
Description: fascial plane injection using ultrasound and fluoroscopic guidance
Study NCT06246162 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lipo-MIT combination regimen
Description: Initial diagnosis induction treatment regimen Lipo-MIT +VD (VMD):~Mitoxantrone Hydrochloride Liposome: 10 mg, d1, d15, intravenous infusion; Bortezomib: 1.3mg/m2 d1, 4, 8, 11, subcutaneous injection; Dexamethasone: 20 mg/d, orally on days 1, 2, 4, 5, 8, 9, 11, and 12. Every 4 weeks constitutes a cycle, and 4 cycles of VMD regimen induction therapy are performed.~Reinduction therapy regimen after relapse Lipo-MIT + PD (PMD):~Mitoxantrone Hydrochloride Liposome: 10 mg, d1, d15, intravenous infusion; Pomalidomide: 4 mg/d d1-d21, orally; Dexamethasone: 20 mg/d, orally on days 1, 2, 4, 5, 8, 9, 11, and 12. Every 4 weeks constitutes a cycle, and 4 cycles of PMD regimen induction therapy are performed.
Study NCT04200937 — intervention group
Intervention type: DEVICE
Intervention: Tactra Malleable
Description: The Tactra™ Penile Prosthesis is a sterile, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in adult males who are suitable candidates for implantation procedure.
Study NCT04200937 — intervention group
Intervention type: DEVICE
Intervention: Spectra™ Concealable Penile Prothesis
Description: The Spectra Penile Prothesis is a sterile, non-pyrogenic, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in men who are determined to be suitable candidates for implantation surgery.
Study NCT04200937 — intervention group
Intervention type: DEVICE
Intervention: AMS Ambicor™ Inflatable Penile Prosthesis
Description: The AMS Ambicor inflatable penile prothesis intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence) in adult men who are determined to be suitable candidates for implantation surgery.
Study NCT04200937 — intervention group
Intervention type: DEVICE
Intervention: AMS 700™ Inflatable Penile Prosthesis w/Momentary Squeeze (MS) Pump
Description: The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).
Study NCT04200937 — intervention group
Intervention type: DEVICE
Intervention: AMS 700™ Inflatable Penile Prosthesis w/Tenacio™ Pump
Description: The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).
Study NCT06149806 — intervention group
Intervention type: DRUG
Intervention: Sacubitril / Valsartan Oral Tablet [Entresto]
Description: efficacy and tolerability of Sacubitril/Valsartan in the treatment of chronic heart failure on complex congenital cardiopathy
Study NCT05510791 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nuun Sport Drink
Description: Subjects will consume a total of 24 ounces water and 1.5 tablets of Nuun SPORT. Specifically, subjects will drink 12 ounces of Nuun drink 15 minutes prior to the 60 min run and 4 ounces of Nuun drink at 15 min, 30 min, and 45 min during the run.
Study NCT05510791 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: SHAM_COMPARATOR
Intervention: Control
Description: Subjects will consume a total of 24 ounces water. Specifically, subjects will drink 12 ounces of water 15 minutes prior to the 60 min run and 4 ounces of water at 15 min, 30 min, and 45 min during the run.
Study NCT05626452 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PrEP Education
Description: Education for participants regarding PrEP
Study NCT05626452 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Provider training
Description: Training for medical providers at CHCs about how to identify participants eligible for PrEP, how to perform behavioral risk assessment and discussion of PrEP, and how to prescribe PrEP and monitor PrEP
Study NCT05626452 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EMR Optimization
Description: EMR modifications to enhance PrEP care continuum outcomes including HIV risk assessment, identification of participants eligible for PrEP, provision of PrEP education, clinical decision support tools for prescription of PrEP, and tracking of PrEP care continuum outcomes using an electronic population health management tool
Study NCT05626452 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PrEP Navigation
Description: Use of CHC staff members to assist participants with obtaining PrEP and attending PrEP care appointments
Study NCT05626452 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Provider Audit and Feedback
Description: Audit of provider rates of PrEP prescription and persistence among participants and regular provision of feedback to providers with their performance on these PrEP measures
Study NCT04775927 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: education
Description: premarital education
Study NCT04782245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin 10mg
Description: The intervention group will receive, during 6 months, dapagliflozin per oral route at a dose of 10 mg once daily in addition to the optimal medical management based on current heart failure practice guidelines.
Study NCT04782245 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients randomized in the control group will receive during 6 months, placebo once daily per oral route, in addition to the optimal medical management based on current heart failure practice guidelines.