AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05139316 — intervention group
Intervention type: GENETIC
Group type: PLACEBO_COMPARATOR
Intervention: DTX401
Description: nonreplicating, recombinant, adeno-associated virus (AAV) serotype 8 (AAV8)
Study NCT05139316 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Normal Saline infusion
Study NCT05139316 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Normal Saline infusion
Study NCT05139316 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral corticosteroids
Description: Participants who receive DTX401 solution will receive oral corticosteroids
Study NCT05139316 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oral corticosteroids
Description: Participants who receive DTX401 solution will receive oral corticosteroids
Study NCT05139316 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo for oral corticosteroids
Description: Participants who receive Placebo will receive placebo oral corticosteroids to maintain the study blind
Study NCT05139316 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for oral corticosteroids
Description: Participants who receive Placebo will receive placebo oral corticosteroids to maintain the study blind
Study NCT06503848 — intervention group
Intervention type: DRUG
Intervention: Sumatriptan
Description: Register the response to treatment and headache characteristics.
Study NCT05549232 — intervention group
Intervention type: DEVICE
Intervention: Hypoxic Red Blood Cells
Description: Hypoxic Red Blood Cells manufactured with the Hemanext ONE device- CPD/PAGGSM Red Blood Cells, Leukocytes Reduced, and O2/CO2 Reduced
Study NCT05015855 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NP-PC PrEP
Description: All participating providers will be provided standard education around PrEP and HIV prevention, but half of the providers will be randomized to also partner with a nurse practitioner who will provide additional consultation to patients.
Study NCT05015855 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: OBGYN-PrEP
Description: OBGYN-PrEP is based on PC4PrEP (R01MH107297) that has four steps: announce the policy that PrEP counseling is the responsibility of OBGYN providers to address the purview paradox; train providers to manage patients on PrEP; use a screening tool to identify women appropriate for PrEP; and implementation coaching to monitor and encourage PrEP counseling
Study NCT04730635 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Donepezil
Description: Donepezil 5 mg capsules for a total daily dose of up to 10 mg QD, orally, for Days 1-56.
Study NCT04730635 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dose matched placebo capsule QD, orally for Days 1-56.
Study NCT06563466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The experimental intervention PEGASUS
Description: See arm description.
Study NCT06563466 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Treatment as usual
Description: See arm description
Study NCT05734443 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: non-treadmill trip training
Description: Participants practice volitional and reactive stepping responses that mimic those needed when recovering balance after tripping.
Study NCT05734443 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: treadmill trip training
Description: Sudden treadmill changes in speed (from standing) induce trip-like losses of balance, after which participants take steps to recover balance and establish a stable gait pattern. This is repeated over a range of speeds to both provide training variability and to individualize training to each participant's capability.
Study NCT06255002 — intervention group
Intervention type: BIOLOGICAL
Intervention: Fibrinogen concentration by the qLabs®FIB Monitoring system
Description: A drop of blood (\~15 μL) is taken from the blood sample for the complete haemostasis assessment (prothrombin level, activated partial thromboplastin time, fibrinogen). This assessment is part of the usual management of severe postpartum haemorrhage. It is carried out urgently in the hospital's medical biology laboratory at the start of treatment (T1) and during or at the end of treatment of the haemorrhage (T2). This drop of blood will allow the measurement of the fibrinogen concentration by the qLabs®FIB Monitoring system for the study at these two times.
Study NCT06651268 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
Description: while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
Study NCT06651268 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
Description: while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
Study NCT05779241 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LYN-005
Description: Risperidone long-acting oral capsule
Study NCT05779241 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risperidone
Description: Risperidone immediate release (IR) oral tablets
Study NCT05312749 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: progressive relaxation exercises
Description: progressive relaxation exercises
Study NCT05148650 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Standard laboratory coagulation tests and rotational thromboelastometry measurements
Description: Blood for coagulation tests (thromboelastometry, aPTT, PT, INR, fibrinogen concentration, D dimers) and blood morphology was collected just before and immediately after the fluid infusion. With the use of a vacuum system, 20 ml of blood was collected through an IV cannula. The first 5 ml of blood were disposed of due to the possible interference with vascular stasis and fluid infusion on the measurements results.~Functional tests of coagulation were analysed through ROTEM. ROTEM coagulation analysis was carried out using a ROTEM delta analyzer (Tem Innovations GmbH, Munich, Germany), and assays were allowed to run for 60 minutes. Assays were run immediately after blood sampling to minimize a preanalytical error. Three ROTEM assays were run simultaneously, INTEM, EXTEM, and FIBTEM.
Study NCT05606211 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: Observational, no intervention
Study NCT04930276 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet intervention
Description: Professionals will guide participants to have a standard diet and require them to monitor blood glucose by themselves.
Study NCT04930276 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Diet intervention
Description: Professionals will guide participants to have a standard diet and require them to monitor blood glucose by themselves.
Study NCT04746118 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DIET CHANGE
Description: Nutritional supervision will be carried out individually based on the Food Guide for the Brazilian Population, ensuring an accessible, hygienic and contextualized diet according to the subject's culture and physiology. The protocol includes an initial assessment to define the meal plan and individual reassessments every four weeks. In the first evaluation participants will receive an eating plan with a 20% reduction in the total calories consumed or even the equivalent of their daily energy needs with a distribution of macronutrients comprised of 65% carbohydrate, 15% protein and 20% fat. The intention is to promote a reduction in weekly consumption by about 2000 kilocalories (Kcal). The prescription and diet control plan will include and be conducted by a team coordinated by a clinical nutritionist.
Study NCT04746118 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PHYSICAL ACTIVITY
Description: The physical activity program will consist of daily walking sessions performed outdoors and on a flat surface suitable for hiking. Each session will last 70 minutes and will be performed between 55% -60% of the maximum oxygen consumption (VO2), six times a week, for 24 weeks, with alternate on-site supervision on odd days and remote monitoring on even days. On-site supervision will be carried out by a team coordinated by a Physical Education teacher and implemented at two times in the morning and another two in the afternoon with meeting points previously defined. At the end of each supervised walking session, 20 minutes of exercise will be performed using the equipment available at the Senior Citizens Academy set up in public squares in the region so that the total expenditure of calories spent weekly with physical activities reach about 2000 kilocalories.
Study NCT04746118 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: INTEGRATIVE PRACTICES
Description: The health integrative practices will includes Mind-Fullness, auriculotherapy and laying on of hands. A suitably qualified professional, using it use a practical manual so that the practice became uniform among the subjects, will apply the practice of Mind-Fullness in weekly 1-hour sessions to individuals. The practice of auriculotherapy will be applied to individuals by a professional qualified to perform the technique, which consists in the selection of auricular points according to the health problems presented and the therapeutic objectives that are to be achieved, followed by the insertion of the mustard seed at specific points in the ear over a six-month period. The laying on of hands will be carried out by properly trained individuals.
Study NCT06136741 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rezpegaldesleukin
Description: Pharmaceutical form: Injection solution Route of administration: subcutaneous
Study NCT06136741 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Pharmaceutical form: Injection solution Route of administration: subcutaneous
Study NCT06136741 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Pharmaceutical form: Injection solution Route of administration: subcutaneous
Study NCT06353178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cancer Connect Program
Description: Online group peer program where participants learn evidence based skills for managing stressors and emotions related to their cancer experience.
Study NCT06353178 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Cancer Connect Program
Description: Online group peer program where participants learn evidence based skills for managing stressors and emotions related to their cancer experience.
Study NCT06117774 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tarlatamab
Description: Intravenous (IV) infusion
Study NCT06117774 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: IV infusion
Study NCT06166303 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: sFlt-1/PGIF
Description: Index of sFlt-1/PGIF
Study NCT05924620 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: finerenone
Description: Patients with PA divided into Intervention group need to take finerenone for 60 days (20mg qd).
Study NCT05466162 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Soft tissue mobilization
Description: Soft tissue massage therapy includes Madenci hand massage technique initiate with 30-second (sec) effleurage, followed by 60- sec friction, 30-sec petrissage, 30-sec shaking, and ends with 30-sec effleurage. It takes totally of 3 min Passive mobilizations of the wrist : radio-carpal joint in flexion and extension, maintained hand in traction. (30 oscillations, 5 sets and 30 secs interval between each step)~Inter-carpal horizontal flexion and extension. (30 oscillations, 5 sets and 30 secs interval between each step)~. Nerve Mobilization treatment( Slider technique) followed by Shoulder will be in depression, abduction on gleno-humeral joint and rotated externally, forearm will be in a supination, elbow flexion and wrist, elbow extension and wrist, thumb, and finger flexion Treatment sessions: 3set, 10 reps, with hold for 10 secs
Study NCT05466162 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Joint and nerve mobilization
Description: Passive mobilizations of the wrist : radio-carpal joint in flexion and extension, maintained hand in traction. (30 oscillations, 5 sets and 30 secs interval between each step)~Inter-carpal horizontal flexion and extension. (30 oscillations, 5 sets and 30 secs interval between each step)~Nerve Mobilization treatment( Slider technique) followed by Shoulder will be in depression, abduction on gleno-humeral joint and rotated externally, forearm will be in a supination, elbow flexion and wrist, elbow extension and wrist, thumb, and finger flexion Treatment sessions: 3set, 10 reps, with hold for 10 secs.
Study NCT05466162 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Joint and nerve mobilization
Description: Passive mobilizations of the wrist : radio-carpal joint in flexion and extension, maintained hand in traction. (30 oscillations, 5 sets and 30 secs interval between each step)~Inter-carpal horizontal flexion and extension. (30 oscillations, 5 sets and 30 secs interval between each step)~Nerve Mobilization treatment( Slider technique) followed by Shoulder will be in depression, abduction on gleno-humeral joint and rotated externally, forearm will be in a supination, elbow flexion and wrist, elbow extension and wrist, thumb, and finger flexion Treatment sessions: 3set, 10 reps, with hold for 10 secs.
Study NCT04869644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Goal setting
Description: Goal setting: set or agree on a goal defined in terms of behavior to be achieved.
Study NCT04869644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Action Planning
Description: Action planning: prompt detailed planning of performance of behavior (must include a setting \[walking to the mailbox\], frequency, duration, and intensity.
Study NCT04869644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-monitoring of behavior
Description: Self-Monitoring of behavior: establish a method for person to monitor and record their number of steps based on their Fitbit.
Study NCT04869644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Practice/Rehearsal
Description: Behavioral rehearsal: prompt practice or rehearsal of walking one or more times in a context when the performance may not be necessary, in order to increase habit and skill.
Study NCT04869644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Habit Formation
Description: Prompt rehearsal \& repetition of walking 2,000 steps or more in the same context repeatedly so that the context elicits the behavior.
Study NCT06499155 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Use of periacryl in gingival recession closure procedures
Description: Unlike the traditional procedure, periacryl tissue adhesive will be used in both the recipient and donor areas.
Study NCT06499155 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Use of sutures in gingival recession closure procedures
Description: Both recipient and donor areas will be closed with traditional suturing techniques.
Study NCT06531109 — intervention group
Intervention type: DRUG
Intervention: Ritlecitinib
Description: As provided in the real world practice.
Study NCT06434610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: B013
Description: B013: The subjects will receive IV dose of B013 600 mg on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.
Study NCT06434610 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel: 80 mg/m\^2 is administered weekly on Day 1, 8, 15 of each 28-day cycle.
Study NCT06434610 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Paclitaxel
Description: Paclitaxel: 80 mg/m\^2 is administered weekly on Day 1, 8, 15 of each 28-day cycle.
Study NCT06434610 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo: The subjects will receive IV dose of placebo matched to B013 on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.
Study NCT05735730 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Blood draw
Description: The study intervention consists of a blood draw for genetic analysis.
Study NCT05744921 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pozelimab
Description: Administered subcutaneously (SC) every 4 weeks (Q4W)
Study NCT05744921 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemdisiran
Description: Administered SC Q4W
Study NCT05857553 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unconditional Cash Transfer
Description: Unconditional monthly transfer of $500 to household
Study NCT05857553 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No Direct Cash Transfer
Description: No intervention
Study NCT05035953 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Edaravone Dexborneol
Description: Edaravone Dexborneol 37.5 mg (containing Edaravone 30 mg and Dexborneol 7.5 mg), BID, 14 days, addition to thrombolysis
Study NCT06306729 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Computed Tomography, Magnetic Resonance Imaging
Description: Computed Tomography, Magnetic Resonance Imaging
Study NCT06658795 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation (tDCS) on the Left DLPFC
Description: The tDCS parameters were set to a current of 2mA for a single session lasting 20 minutes. For stimulating the lDLPFC, the positive electrode was placed at position F3, and the negative electrode was placed in the right supraorbital area/FP2 (e.g., Dubreuil-Vall et al., 2021, Biol Psychiatry: CNNI).
Study NCT06658795 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation (tDCS) on the right VLPFC
Description: The tDCS parameters were set to a current of 2mA for a single session lasting 20 minutes. Based on the EEG 10-20 international system, the positive electrode for stimulating the rVLPFC was placed at position F6, while the negative electrode was placed in the left supraorbital area/FP1 (e.g., He et al., 2020, Psychol Med)
Study NCT06658795 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation group
Description: The electrode positions were randomized to match those of the rVLPFC or lDLPFC groups, but the stimulation only lasted for the first 30 seconds.
Study NCT06659848 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high intensity interval training
Description: The subjects in the four groups performed 12 weeks of supervised HIIE program on a motorized treadmill (h/p/cosmos, Pulsar 4.0, Nussdorf-Traunstein, Germany) with a rate of three sessions weekly. The session commenced with a 5 min warming-up and concluded with a 5 min cooling down period. The exercise effort component consisted of 5 intervals of HIIT. Each interval continues for four min of HIIT with exercise intensity ranging from 75% to 90% of the peak heart rate. Each active recovery period between exercise intervals included moderate exercise at intensity of 50% to 60% of the peak heart rate. Every 3 weeks, the exercise intensity was increased by 5% starting with 75% of the HRmax in the first 3 weeks, 80% in the following 3 weeks and progressed to 90% the HRmax in the last 3 weeks. The subject's heart rate throughout the HIIT session was monitored using a polar heart rate monitor (Polar, Kempele, Finland).
Study NCT06097832 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NXC-201 CAR-T
Description: NXC-201 (formerly HBI0101) CAR-T is defined as autologous T cells transduced ex-vivo with anti-BCMA CAR retroviral vector encoding the chimeric antigen receptor (CAR) targeted to human BCMA. The NXC-201 CAR-T is provided fresh without cryopreservation.
Study NCT05265312 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: START diabetes prevention clinical pathway
Description: The diabetes prevention clinical pathway will focus on the following steps:~1. Screen/test - testing of eligible patients for prediabetes/diabetes~2. Education - PCPs will be encouraged to take an online learning module and in-person group training on prediabetes management and patients with prediabetes will receive a handout about prediabetes prior to their upcoming PCP visit~3. Action - PCPs will use a shared decision-making guide and treatment algorithm to discuss options with patients at their visit~4. Referral - patients may be referred to DPPs and/or medical nutrition therapy (MNT)~5. Treat - patients will be scheduled for a follow-up visit within 3-9 months with their PCP or care team to continue addressing prediabetes.
Study NCT06662071 — intervention group
Intervention type: OTHER
Intervention: Organoid culture
Description: Organoid culture of tumor tissue obtained during patient surgery
Study NCT06659510 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: education
Description: ACCORDING TO THE RESULTS AFTER THE SURVEY APPLICATION, TRAINING WAS PROVIDED TO THE ADDICTIVE STUDENTS IN THE EXPERIMENT GROUP AND MESSAGES WERE SENT FROM WHATSAPP APPLICATION IN THE FOLLOWING 2 MONTHS AFTER THE TRAINING.
Study NCT06658834 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone Combined with romiplostim N01
Description: Dexamethasone (HD-DXM) at a dose of 40mg/d for 4 days constitutes one cycle. If there is no response on the 10th day, repeat it once. The administration can be either oral or intravenous. Meanwhile, romiplostim N01 is administered with an initial dose of 3µg/kg by subcutaneous injection once a week for up to 6 months.
Study NCT06658834 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone monotherapy
Description: Dexamethasone (HD-DXM) 40mg/d × 4 days, one cycle. If there is no response on the 10th day, repeat once, administered either orally or intravenously.
Study NCT06660186 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rigid Sternal Fixation
Description: The surgeon will close the sternum (breastbone) using the SternalPlate system. The SternalPlate System consists of implants and instruments used to hold the two halves of the sternum together.