AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06609733 — intervention group
Intervention type: DEVICE
Intervention: Twin block
Description: The TB group used a single appliance continuously, with appropriate reduction of occlusal surface height by 1 mm when clinically indicated. Both groups had follow-up appointments every 6 weeks.
Study NCT06609733 — intervention group
Intervention type: DEVICE
Intervention: Clear aligner with mandibular function
Description: The MA group underwent stepwise mandibular forward movement with clear aligners (Invisalign, Align Inc, CA, USA) worn for 22 hours/day and replaced every 7 days.
Study NCT06610565 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: FASTING-MIMICKING DIET PROGRAM
Description: Nutritional intervention via fasting-mimicking diet. Patients receiving adjuvant therapy with aromatase inhibitors will be randomized 1:1 into two arms: one intervention, where will receive nutritional counseling and the study diet for 5 days each month for 6 months,and a control one, where they will receive only nutritional counseling.
Study NCT05581563 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: total knee arthroplasty(TKA)
Description: Knee replacement, also called knee arthroplasty or total knee replacement, is a surgical procedure to resurface a knee damaged by arthritis. Metal and plastic parts are used to cap the ends of the bones that form the knee joint, along with the kneecap. This surgery may be considered for someone who has severe arthritis or a severe knee injury.
Study NCT05581563 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: total knee arthroplasty(TKA)
Description: Knee replacement, also called knee arthroplasty or total knee replacement, is a surgical procedure to resurface a knee damaged by arthritis. Metal and plastic parts are used to cap the ends of the bones that form the knee joint, along with the kneecap. This surgery may be considered for someone who has severe arthritis or a severe knee injury.
Study NCT01531634 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic Cognitive Intervention Group
Description: Twelve meetings of a Dynamic Cognitive Intervention group.
Study NCT06609395 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief online CBT targeting excessiv worry
Description: The intervention with a focus on excessive worry lasted five weeks and was delivered through five online modules with therapist support. Modules covered psychoeducation, problem-solving, reducing excessive media consumption, detached mindfulness, and shifting focus from worry. The final module offered relapse prevention strategies.
Study NCT06610305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal estradiol
Description: 0.1 mg/day delivered via weekly patch
Study NCT04507113 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DTI sequence acquisition
Description: DTI sequence acquisition
Study NCT05392400 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Steri3X
Description: This study will initially attempt to recruit pregnant patients at the Regional One Health outpatient obstetrics clinic, at which point they will be randomly assigned to one of two cohorts. Participants who are consented to participate in the study will receive a chart flag in the EMR so that they may receive the proper intraoperative and postoperative treatment(s). Patients randomized to receive the Steri3X wound dressing will have the liquid polymer applied in the operating room after closure of the Cesarean section incision. Participants of both arms will be monitored postoperatively to assess for signs and symptoms of postoperative surgical site infection(s).
Study NCT05392400 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Device: Steri3X~This study will initially attempt to recruit pregnant patients at the Regional One Health outpatient obstetrics clinic, at which point they will be randomly assigned to one of two cohorts. Participants who are consented to participate in the study will receive a chart flag in the EMR so that they may receive the proper intraoperative and postoperative treatment(s). Patients randomized to receive the control wound dressing will have the current standard of care dressing applied in the operating room after closure of the Cesarean section incision. Participants of both arms will be monitored postoperatively to assess for signs and symptoms of postoperative surgical site infection(s).
Study NCT06521242 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Education
Description: The intervention group was given 120 minutes of training.
Study NCT06480708 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: The ketogenic diet consisting of fats (70%), protein (20%) and carbohydrates (10%) will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
Study NCT06610305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Progesterone
Description: 100 mg twice daily (200 mg/day total) administered via oral capsule
Study NCT06610305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal placebo patch
Description: Once weekly via transdermal patch
Study NCT06610305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo capsule
Description: Twice daily via oral capsule
Study NCT06609551 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6-month adjuvant chemotherapy with 5-FU monotherapy
Description: 6 months of adjuvant chemotherapy with 5-FU monotherapy. The follow-up strategy for the four groups of subjects will be the same, including but not limited to chest plain or enhanced CT, abdominal/pelvic enhanced CT, and detection of the tumor marker carcinoembryonic antigen (CEA), until disease progression occurs. All patients will undergo peripheral blood ctDNA-MRD testing again six months after surgery.
Study NCT06609551 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XELOX intensive treatment group
Description: XELOX intensive treatment group. The follow-up strategy for the four groups of subjects will be the same, including but not limited to chest plain or enhanced CT, abdominal/pelvic enhanced CT, and detection of the tumor marker carcinoembryonic antigen (CEA), until disease progression occurs. All patients will undergo peripheral blood ctDNA-MRD testing again six months after surgery.
Study NCT06609954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Reduced Exertion High Intensity Training (REHIT)
Description: Participant will perform a 5 min warm-up exercises then do cycling or treadmill running for 20 min at 40%-60% of HRR and then will conclude with 5 min cool down exercises. From week 2 to 6 participants will be instructed to perform training sessions on a cycle ergometer. Each session will consist of a 3-minute warm-up period followed by two 20-second all-out sprints interspersed with 3 minutes of slow pedaling for recovery. Total of 18 sessions of REHIT will be performed thrice a week on alternate days by the participants for consecutive 6 weeks.
Study NCT06609954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training (HIIT)
Description: Patients in this group will be provided with a caloric restriction plan by a nutritionist that will be followed throughout the training duration. Week 1 will be baseline fitness level and familiarization week. Participant will perform a 5 min warm-up exercises then do cycling or treadmill running for 20 min at 40%-60% of HRR and then will conclude with 5 min cool down exercises. From week 2 to 6 participants will be instructed to perform a warm up of 5 min, then 4 bouts of 4 min of HIIT will be performed at 80%-95% of HRR separated by 3-min active recovery periods of moderate intensity cycling at 60%-70% of the HRR followed by 5 min cool down exercises. Pre and post session vitals will be noted. Total of 18 sessions of either HIIT will be performed thrice a week on alternate days by the participants for consecutive 6 weeks.
Study NCT06610006 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High Intensity Interval Training (HIIT)
Description: High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.
Study NCT06610006 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training (HIIT)
Description: High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.
Study NCT06610006 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Isometric Wall Squat
Description: For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods. In first week, participants will do squat training or there will be a protocol for selecting exercise intensity in which participants will be given 30-s to perform a wall squat to select a position that they predict would elicit an target RPE score by varying the squat height. Based on the final squat height and RPE score, after bout 4, participants will be given a starting squat height for training session 1 and will then be progressed in each week
Study NCT05172609 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure Based Implementation Strategy (EBIS)
Description: EBIS will include psychoeducation, assessment/hierarchy building. guided practice, and guidance for application to clinical practice.
Study NCT05172609 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Implementation as Usual (IAU)
Description: IAU will consist of standard didactic training and ongoing consultation activities for enrolled clinicians
Study NCT06480708 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control diet
Description: The control diet consisting of a Mediterranean diet, at 25% fat, 20% protein and 55% carbohydrates will be consumed for 14 days prior to undergoing open-heart surgery, and up to 6 days postoperatively or until discharge (if within 6 days postoperatively).
Study NCT04890379 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dimethyl fumarate
Description: Dimethyl fumarate 240mg orally twice daily for 3 consecutive days
Study NCT04890379 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 240mg orally twice daily for 3 consecutive days
Study NCT06313164 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: enhanced glutathione
Description: L-glutathione (in combination with tannin, low molecular weight chitosan and polyethylene glycol)
Study NCT06313164 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo comparator
Description: placebo group
Study NCT06611332 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electroacupuncture
Description: The main acupoints selected for the electroacupuncture group are bilateral BL23, bilateral BL25, bilateral GB30, bilateral LR11, bilateral LR8, GV4, GV3, and the affected BL40, and the secondary acupoints selected are bilateral BL54, the affected side BL57 and the affected side BL60.The treatment will be administered once every other day for 30 minutes each time, lasting for 8 consecutive weeks, totaling 24 sessions.
Study NCT06611332 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham electroacupuncture
Description: In the sham electroacupuncture group, the acupoints will be at a position 2 cm lateral to the correct acupoints horizontally. The dosage and treatment course are the same as those in the electroacupuncture group.
Study NCT05559476 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSVPreF3 OA investigational vaccine
Description: RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm.
Study NCT05559476 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: RSVPreF3 OA investigational vaccine
Description: RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm.
Study NCT05559476 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FLU HD vaccine
Description: FLU HD vaccine administered intramuscularly in the deltoid region of the dominant arm (Co-Ad Group) or the non-dominant arm (Control Group).
Study NCT04935073 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prescription of traditional Chinese Medicine named Er Zhi Wan combined with Si Wu Tang
Description: The medicines used in this study including Radix et Rhizoma Ligustrum 15 g, Radix Morindae Sinensis 12 g, Fructus Lycii 15 g, Semen Cuscutae 20 g, Radix Rehmanniae 15 g, Radix Angelicae Sinensis 10 g, Radix Paeoniae Alba 10 g, Ligusticum wallichii 6 g, Poria cocos 15g, Polygonatum 15g, eclipta 10g. which will be taken for 10-15days.After the ET, the treatment group will continue to take Chinese herbal medicine, changing to Shou Tai pills ( Morinda officinalis 15 g, Teasel 15g，Cuscutae 20 g, Eucommia ulmoides 15 g, Rehmannia 15 g, Cornus officinalis 15 g, loranthus parasiticus 20 g, Ligustrum lucidum 15g, Salvia miltiorrhiza 10g, Scutellaria baicalensis 10g, Atractylodes macrocephala 15g); which will be taken for 14days. The hospital will be responsible for the decoction of 200 mL per dose, 1 dose per day, divided into 2 doses in the morning and in the evening.
Study NCT04935073 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Human Follitropin Alfa for Injection、Fructose Injection、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder for Injection
Description: The intervention starts from the 5th day of the menstrual cycle and lasts to the day before IVF-ET.
Study NCT04935073 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Recombinant Human Follitropin Alfa for Injection、Fructose Injection、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder for Injection
Description: The intervention starts from the 5th day of the menstrual cycle and lasts to the day before IVF-ET.
Study NCT05415358 — intervention group
Intervention type: OTHER
Intervention: Blood and tissue samples
Description: Blood and tissue will be collected to perform ctDNA and immune biomarkers assessment to predict progression within 6 months of pembrolizumab discontinuation.
Study NCT05559476 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: FLU HD vaccine
Description: FLU HD vaccine administered intramuscularly in the deltoid region of the dominant arm (Co-Ad Group) or the non-dominant arm (Control Group).
Study NCT06502496 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: art-therapy
Description: Over the 6 sessions, different artistic techniques will be explored, depending on the artist leading the workshop: stencil, graffiti, spray paint, collage, oil pastel, calligraphy and acrylic doodling. A collective work may also be proposed.
Study NCT06502496 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: relaxation
Description: relaxation sessions with the referent psychologist
Study NCT06144463 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: lung ultrasound-guided fluid resuscitation
Description: For the LUGFR group, therapy was applied based on the same treatment guidelines, and initial lung ultrasonography was performed after enrollment as baseline assessment of lung. The lung ultrasound was conducted using the Doppler ultrasound diagnostic instrument (Philips CX50) at a probe frequency range of 8 to 12 MHz. Lung ultrasonography was conducted using the 12-region method that included the anterior, lateral, and posterior walls on both sides of the lung, which was focused on the condition of A-lines, B-lines (including confluent B-line and compact B-lines), lung consolidation and pleural effusion
Study NCT06144463 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: lung ultrasound-guided fluid resuscitation
Description: For the LUGFR group, therapy was applied based on the same treatment guidelines, and initial lung ultrasonography was performed after enrollment as baseline assessment of lung. The lung ultrasound was conducted using the Doppler ultrasound diagnostic instrument (Philips CX50) at a probe frequency range of 8 to 12 MHz. Lung ultrasonography was conducted using the 12-region method that included the anterior, lateral, and posterior walls on both sides of the lung, which was focused on the condition of A-lines, B-lines (including confluent B-line and compact B-lines), lung consolidation and pleural effusion
Study NCT06427408 — intervention group
Intervention type: OTHER
Intervention: Non applicable
Description: Placental transcriptomic analysis
Study NCT05269160 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dermaprazole 1%
Description: Dermaprazole cream at a concentration of 1% will be applied to the irradiated area twice daily for up to 7 weeks
Study NCT05269160 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dermaprazole 2%
Description: Dermaprazole cream at a concentration of 2% will be applied to the irradiated area twice daily for up to 7 weeks
Study NCT04954404 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcatheter mitral valve repair/transcatheter mitral valve replacement
Description: transcatheter mitral valve repair/transcatheter mitral valve replacement
Study NCT06436118 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RELAX® glasses
Description: Glasses which are a solution of audiovisual sedation by positive distraction for hospital medical use.
Study NCT06262308 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological intervention along Cognitive Behavioural Therapy principles
Description: Women who have PPROM will be offered a series of 6 sessions with a Clinical Psychologist
Study NCT05294315 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bi-level erector spinae block
Description: erector spinae block at 4th and 6th transverse process
Study NCT05294315 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Single level erector spinae block
Description: erector spinae block at 4th transverse process
Study NCT05829954 — intervention group
Intervention type: OTHER
Intervention: questionnaire
Description: All questionnaire were obtained via online survey system.
Study NCT05762497 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Moldable adhesive
Description: Patients were provided with the new adhesives and a short questionnaire on current ASV use. After a week, they were contacted by telephone to verify any doubts/problems. At the end of the two weeks, the patient was again administered a questionnaire to evaluate the new moldable adhesive (while using the ASV).
Study NCT06426953 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT06166940 — intervention group
Intervention type: OTHER
Intervention: ROTEM Guided Management
Description: ROTEM guided management of hemostasis after CPB
Study NCT06532396 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QRL-101
Description: Multiple-ascending doses of QRL-101 will be orally administered. The dose levels may change subject to available nonclinical, clinical, safety, and PK data.
Study NCT06532396 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Multiple-ascending doses of comparator placebo will be administered orally to healthy participants.
Study NCT05205187 — intervention group
Intervention type: PROCEDURE
Intervention: Healthy control specimen collection
Description: Collecting blood and feces from healthy population.
Study NCT05205187 — intervention group
Intervention type: PROCEDURE
Intervention: Non-Borrmann IV patient specimen collection
Description: Collecting blood, feces and gastric cancer tissues from Non-Borrmann IV patients.
Study NCT05205187 — intervention group
Intervention type: PROCEDURE
Intervention: Borrmann IV patient specimen collection
Description: Collecting blood, feces and gastric cancer tissues from Borrmann IV patients.
Study NCT05857644 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07923568
Description: One time dose of 4 capsules taken orally.
Study NCT06298240 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: nursing procedure for acute health problems of low complexity
Description: An agreed nursing procedure is applied for users of a primary care emergency center who spontaneously consult for 5 acute health problems of low complexity: gastroenteritis, cystitis in women, dental pain, upper respiratory tract affections and acute wounds
Study NCT05206175 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Affect Treatment Program for Methamphetamine Use Disorder
Description: Telemedicine based group and individual therapy, drug screens, contingency management, therapeutic app engagement, psychiatric interventions for adjuvant medications.