AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05930821 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic and Resistance Exercise Program (GEMS program)
Description: * Remotely-coached/guided, home-based program delivered using telerehabilitation focusing on aerobic fitness and muscle strength as a mode of training.~* The exercise training prescription involves performing 3 days per week and include (a) aerobic exercise: 30+ minutes of moderate-intensity walking (≥100 steps/min) monitored by a waist-worn pedometer, and (b) resistance training: 1-2 sets, 10-15 repetitions of 5-10 exercises targeting lower and upper body, and core muscle groups using elastic bands.~* Other components of the GEMS program include appropriate exercise equipment (pedometer, resistance bands), one-on-one coaching sessions via Zoom, action-planning via calendars, logbooks for self-monitoring, and SCT-based newsletters.
Study NCT05930821 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Flexibility and Stretching Program (FLEX-MS program)
Description: * Remotely-coached/guided, home-based program delivered using telerehabilitation focusing on stretching and range of motion as the mode of training.~* The training will involve the same frequency, duration, timeline, behavior change content, and interactions with behavioral coach as the GEMS program, and account for activity, social-contact, and attention.~* Other components of the FLEX-MS program include appropriate exercise equipment (yoga mat), one-on-one coaching sessions via Zoom, calendars, logbooks and newsletters similar to the GEMS program.
Study NCT06408870 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: BI 1015550
Study NCT04384809 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Leukocyte rich platelet rich plasma
Description: Leukocyte rich platelet rich plasma will be obtained and prepared from a peripheral artery of the subject and then will be injected in the common extensor tendon
Study NCT04384809 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous Tenotomy
Description: Patients will undergo percutaneous tenotomy of the common extensor tendon using the Tenex tenotomy device
Study NCT05635344 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Single dose 200mg dose of Pembrolizumab given intravenously
Study NCT06207786 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Povidone-Iodine Swabs
Description: Undergo nasal swab of both nostrils for 30 seconds into each nostril, allowing two minutes to dry, immediately (e.g. within 30 minutes) prior to performing skin reconstruction.
Study NCT06207786 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Staphylococcus nasal swab
Description: Undergo a nasal swab to identify patients with preoperative nasal Staphylococcus aureus colonization
Study NCT06207786 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Staphylococcus nasal swab
Description: Undergo a nasal swab to identify patients with preoperative nasal Staphylococcus aureus colonization
Study NCT06207786 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Antibiotic
Description: Receive an oral anti-staphylococcal antibiotic (e.g. oral cephalexin) with standard dosing only if indicated for antibiotic prophylaxis per the Mayo Clinic Dermatologic Surgery Antibiotic Prophylaxis protocol that is currently standard practice for patients undergoing Mohs micrographic surgery (MMS)
Study NCT04637386 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transversus Abdominis Plane Block
Description: A 22-gauge spinal needle was introduced from medial to lateral in-plane to the ultrasound probe, and 20 mL of bupivacaine 0.25% was injected under visualization in the plane between the transversus abdominis muscle and the fascia deep to the internal oblique muscle on each side.
Study NCT04637386 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local anesthetic wound infiltration
Description: 40 mL of bupivacaine 0.25% was injected subcutaneously into the surgical wound (20 mL on each of the upper and lower sides) by the obstetrician before skin closure
Study NCT06385769 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous tibial nerve stimulation (TTNS)
Description: The TTNS will be conducted unilaterally, with the patient in a supine position, using a surface electrode dual stimulation channel stimulation device. Two self-adhesive round surface electrodes will be positioned with the negative electrode 2 cm behind the medial malleolus and the positive electrode 10 cm proximal to it. The ground electrode will be placed on the ipsilateral limb. Channel 1 will provide active stimulation, while channel 2 will remain inactive.
Study NCT06385769 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Transcutaneous tibial nerve stimulation (TTNS)
Description: Sham TTNS group will be stimulated using the same electrotherapy device, with patients positioned identically and electrodes placed in the same positions as in the TTNS group. The current characteristics (pulse frequency 20 Hz and pulse width 200 ms) will also remain consistent across both channels. The second channel of the stimulation device will be designated as the channel connected to the patient but without delivering stimulation.
Study NCT05594550 — intervention group
Intervention type: OTHER
Intervention: Data collection
Description: Demographic data:~Age, Sex, weight, height, main history and treatments.~- Biological data: CRP, PCT, albumin, pre-albumin
Study NCT05594550 — intervention group
Intervention type: OTHER
Intervention: analysis of thoracic scans
Description: muscle area calculated on the T7 and T12 thoracic slices
Study NCT06079138 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation (Active)
Description: Participants will sit comfortably during the stimulation, and the scalp will be cleaned with alcohol beforehand. The Ybrain MINDD STIM current stimulator will be used with saline-soaked sponge-pad electrodes (35 cm2 in size). Electrode placement will follow the 10-20 EEG system, with the active (anodal) electrode (A) positioned at the vertex (Cz) on the more affected side and the reference (cathodal) electrode (C) placed over the supraorbital region on the less affected side. The electrodes will be attached to a cap before application.~In the experimental group, participants will receive real tDCS at 2.0 mA for 20 minutes, with a 30-second ramp-up and ramp-down period.
Study NCT06079138 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial direct current stimulation (Sham)
Description: Participants will sit comfortably during the stimulation, and the scalp will be cleaned with alcohol beforehand. The Ybrain MINDD STIM current stimulator will be used with saline-soaked sponge-pad electrodes (35 cm2 in size). Electrode placement will follow the 10-20 EEG system, with the active (anodal) electrode (A) positioned at the vertex (Cz) on the more affected side and the reference (cathodal) electrode (C) placed over the supraorbital region on the less affected side. The electrodes will be attached to a cap before application. The sham group will receive sham tDCS, where the current will only be delivered for the first 30 seconds and automatically stopped, while the electrodes remain in place for 20 minutes.
Study NCT06079138 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telerehabilitation exercise
Description: Telerehabilitation exercise will be provided via tele-conference meeting program. The program will consist of 3 parts. First part, there will be a limb exercise program for 20 minutes to prepare the joint range of motion and muscles. Second part, participants will receive functional balance training for 15 minutes to promote their postural balance during changing positions and static positions. Each exercise will perform 10 repetitions for each set and perform 3 sets. After 2-week of intervention, the set will be progressed to 4 sets. Final part, participants will receive 20 minutes of functional training of wheelchair/bed transferring exercise. Each wheelchair and bed transfer exercise will perform 10 repetitions for each completely transfer and perform 3 sets. After 2-week of intervention, the set will be progressed to 4 sets. After finishing all the programs, they will be asked to cool down by doing breathing exercises with torso stretching for 5 minutes.
Study NCT06079138 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Telerehabilitation exercise
Description: Telerehabilitation exercise will be provided via tele-conference meeting program. The program will consist of 3 parts. First part, there will be a limb exercise program for 20 minutes to prepare the joint range of motion and muscles. Second part, participants will receive functional balance training for 15 minutes to promote their postural balance during changing positions and static positions. Each exercise will perform 10 repetitions for each set and perform 3 sets. After 2-week of intervention, the set will be progressed to 4 sets. Final part, participants will receive 20 minutes of functional training of wheelchair/bed transferring exercise. Each wheelchair and bed transfer exercise will perform 10 repetitions for each completely transfer and perform 3 sets. After 2-week of intervention, the set will be progressed to 4 sets. After finishing all the programs, they will be asked to cool down by doing breathing exercises with torso stretching for 5 minutes.
Study NCT04808115 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KDS-1001
Description: Cycles 1-6 (14 days per cycle)~1 x 109/KDS-1001 cells/infusion administered on day 1 of each cycle
Study NCT05966454 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Multiple standard of care antibiotics for appendicitis, at physicians' discretion
Description: Standard of Care Antibiotic use will be restricted to none or up to 24 hours of post-operative antibiotics.
Study NCT05966454 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Multiple standard of care antibiotics for appendicitis, at physicians' discretion
Description: Standard of Care Antibiotic use will be permitted for 24 hours or up to 4 days of post-operative antibiotics.
Study NCT04935385 — intervention group
Intervention type: OTHER
Intervention: Collecting blood specimens
Description: Blood samples will be collected from all study participants at different required timelines
Study NCT05357573 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KRN23
Description: KRN23 is a sterile clear colourless and preservative free solution supplied in single use 5 mL vials containing 1 mL of KRN23 at a concentration of 30mg/mL
Study NCT05350722 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Single dose ablative radiotherapy
Description: Patients will receive a single dose of 20Gy/15Gy on the gross tumor volume and clinical tumor volume respectively, in the context of pre-operative partial breast irradiation
Study NCT06373016 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Glucose
Description: A glucose drink is administered midway through one of the scan sessions.
Study NCT06373016 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketones
Description: A ketone drink is administered midway through one of the scan sessions.
Study NCT05559177 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Chimeric exosomal tumor vaccines
Description: Tumor cells (lesion site) were isolated from bladder cancer patients, and bladder cancer nuclei were extracted. Monocytes were isolated from peripheral blood of this patient and induced in vitro to obtain APC (DC or macrophage). Apc-tumor chimeric cells were constructed and stimulated with immune stimulator. Chimeric exosomal vaccines were extracted from cell supernatants by differential and hypervelocity centrifugation
Study NCT05454735 — intervention group
Intervention type: PROCEDURE
Intervention: coronary artery bypass surgery
Description: coronary artery bypass surgery
Study NCT05454735 — intervention group
Intervention type: PROCEDURE
Intervention: aortic valve replacement surgery
Description: aortic valve replacement surgery
Study NCT06473727 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Omnichoroma
Description: Patients with anterior non-carious cervical lesions were treated with Omnichoroma. Colour measurements were taken from the middle third of the teeth to be treated using a spectrophotometer. The initial colour measurement was taken from the middle third of the restoration made in the same place and at the same time 24 hours after treatment.
Study NCT06473727 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Charisma Topaz One
Description: Patients with anterior non-carious cervical lesions were treated with Charisma Topaz One. Colour measurements were taken from the middle third of the teeth to be treated using a spectrophotometer. The initial colour measurement was taken from the middle third of the restoration made in the same place and at the same time 24 hours after treatment.
Study NCT05034146 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-FAPI
Description: 68Ga-FAPI was injected intravenously to each subject, and the dose is calculated according to body weight of subject (approximately 1.85-3.7MBq/kg).
Study NCT05034146 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PET/CT
Description: 68Ga-FAPI PET/CT scan were performed 20\~60 min after 68Ga-FAPI (1.85-3.7MBq/kg) injection intravenously.
Study NCT00272493 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Hepatitis B virus vaccine with GM-CSF adjuvant
Description: Arm B participants will receive 40 mcg of HBV vaccine and 250 mcg of GM-CSF at study entry, Week 4, and Week 12.
Study NCT00272493 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hepatitis B virus vaccine
Description: Arm A participants will receive 40 mcg of HBV vaccine at study entry, Week 4, and Week 12.
Study NCT05953545 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon Lambda
Description: Study intervention for this protocol includes a weekly subcutaneous injection of peginterferon lambda at a dose of 180 mcg and an oral twice daily dosing of Lonafarnib at 50mg boosted with twice daily Ritonavir at 100mg for 48 weeks. Following 48 weeks of treatment the subjects will be monitored for outcomes during an additional 6-month time period.
Study NCT05494840 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Haptonomy
Description: Haptonomy, as a field dealing with emotional contact through touch, describe the relationship between parents and the unborn baby.
Study NCT04673318 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: heat therapy
Description: leg heated garments with circulating water to conduct heat therapy at home
Study NCT04673318 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: exercise training
Description: A velocity based training program will be implemented at home using a mobile app allowing for the quantification the relative intensity.
Study NCT05247372 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: The effect of Iyengar yoga practice on patients with multiple sclerosis
Description: The study will be conducted as a longitudinal follow-up - at first patients will fbe examined 2 months before the start of the exercise, than they will be examined at the beginning and end of the exercise, which they will attend for 3 months. Patients will be re-examined 2 months after the end of the exercise to clarify the continuing effect of the exercise. The examination will include a basic kinesiological analysis and a neurological examination,TUG test, 6MWT along with the Borg Subjective Weight Rating Scale and T25FWT, BBS, NHPT and stable sitting time in wheelchairs. To evaluate the development of the chest, the respiratory amplitude will be examined and the position of the spine in statics and dynamics will be evaluated using a spinal mouse. Quality of life will be assessed through the MFIS, MSIS-29, MSQOL 54 questionares and Beck's anxiety inventory.
Study NCT06566118 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Auricular Vagus Nerve Stimülation
Description: Both groups were subjected to exercise loading, then Group 1 was subjected to active auricular VSS, and Group 2 was subjected to sham VSS. The application was made simultaneously from both ears, with a pulse duration of 300 microseconds, a biphasic asymmetric waveform and a frequency of 25 Hz for a total of 20 minutes. All evaluations were recorded 3 times for both groups: at the beginning of the test, after exercise loading, and after active and sham VSS application. As a result of the evaluations made for both groups, comparisons were made between and within the groups.
Study NCT06566118 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Auricular Vagus Nerve Stimülation
Description: Both groups were subjected to exercise loading, then Group 1 was subjected to active auricular VSS, and Group 2 was subjected to sham VSS. The application was made simultaneously from both ears, with a pulse duration of 300 microseconds, a biphasic asymmetric waveform and a frequency of 25 Hz for a total of 20 minutes. All evaluations were recorded 3 times for both groups: at the beginning of the test, after exercise loading, and after active and sham VSS application. As a result of the evaluations made for both groups, comparisons were made between and within the groups.
Study NCT04970563 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Body odor samples
Description: Participants will provide six body odor samples (mask and sweat samples) at inclusion
Study NCT04970563 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Body odor samples
Description: Participants will provide six body odor samples (mask and sweat samples) at inclusion
Study NCT04970563 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Body odor samples
Description: Participants will provide six body odor samples (masks and compresses) at inclusion. A 7-day follow-up will be carried out to check, respectively, the absence of symptoms and the persistence of negativity on the SARS-COV-2 PCR test
Study NCT06514157 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: budesonide/albuterol sulfate metered dose inhaleor (BDA MDI)
Description: BDA MDI 160 μg/180 μg (single dose administered as 2 actuations of 80 μg/90 μg)
Study NCT05179252 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Shen-Fu injection
Description: Chinese patent medicine made by modern technology
Study NCT05179252 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: normal saline
Description: 0.9% normal saline, used for sham control
Study NCT06329908 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LG002
Description: Neo-DCVac combined with ICIs in the treatment of advanced lung cancer resistant to ICIs.
Study NCT04739982 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GuessWhat Mobile App
Description: The GuessWhat app is a charades style game and app that engages parent and child in fluid social interaction where the parent must guess what the child is acting out based on the prompt shown on the phone screen. Participants will use their own personal phone to download the study app. Parent and child will be encouraged to play using the emojis and emotion game mode at least 3 individual game sessions per week. Parents are asked to play GuessWhat with their child 3-4 times per week for 4 weeks.
Study NCT03380728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibogaine Hydrochloride
Description: The first 3 patients will receive oral doses of 20 to 400 mg of ibogaine in an open-label design. If the 3 higher doses (240, 320 and 400 mg) are well tolerated, the next 9 volunteers will receive these doses or placebo randomly in 3 different groups.
Study NCT04741581 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: ThickenUp® Gel Express
Description: Thickening gel
Study NCT05112952 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lazertinib
Description: Lazertinib tablet will be administered orally.
Study NCT05112952 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lazertinib
Description: Lazertinib tablet will be administered orally.
Study NCT05523765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Brepocitinib
Description: Oral Brepocitinib
Study NCT06389396 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CP362 Test Catheter
Description: The investigational device is intended to perform TAI procedures together with the CE-marked Peristeen Plus TAI system.
Study NCT05553509 — intervention group
Intervention type: OTHER
Intervention: PER CUTANEOUS TRANSLUMINAL ANGIOPLASTY
Description: SURGICAL DEBRIDEMNT
Study NCT05405920 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Team-based Care Strategy for Hypertension Control
Description: The core component of the intervention is a stepped-care protocol, based on the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) Clinical Practice Guideline for High Blood Pressure and the 2021 World Health Organization (WHO) Hypertension Guideline. Using a team-based care model, a physician-nurse-CHW team will work with patients to implement clinical guideline-based treatment in all intervention clinics. Team-based care components will include task sharing and shifting, health care team training, home BP monitoring, BP audit and feedback, and CHW-led health coaching on lifestyle modification and medication adherence.
Study NCT05405920 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: We will train the primary care physicians, nurses, and other clinic staff in performing standardized BP measurements. We will offer physician education on clinical guidelines for hypertension management and issue continuing medical education credits. Patient educational materials will be distributed. We will not conduct any other interventions in the enhanced usual care clinics.
Study NCT06179407 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-6552
Description: Oral capsule administered according to allocation (Part 1)/randomization (Part 2).
Study NCT06138314 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Exercise Program
Description: The physical exercise program will consist of exercises from three different exercise modalities: aerobic training, balance exercises, and isometric exercises.