AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06326788 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SUSTAINED SOLEUS PUSH-UPS
Description: Participants will start soles push-ups in sitting. To do so, the participants will be in a seated position, the legs will be at 90 degrees to the floor, and the feet will be placed flat on the ground.~Participants will then move their heels up and down continuously. Sustained soleus push-ups will be performed with light intensity for up to 270 mins.~No external resistance will be added. Participants will be provided with a maximum 4-minute break time after every 90 mins intervention. In the meantime, their blood sample will be collected.
Study NCT06509165 — intervention group
Intervention type: PROCEDURE
Intervention: Modified coronally advanced flap technique
Description: Subepithelial connective tissue graft was applied to the relevant areas with a modified coronally placed flap technique to cover the gingival recession.
Study NCT06509165 — intervention group
Intervention type: PROCEDURE
Intervention: Tunnel technique
Description: Subepithelial connective tissue graft was applied to the relevant areas with the tunnel technique to cover the gingival recession.
Study NCT04727294 — intervention group
Intervention type: BEHAVIORAL
Intervention: Questionnaire
Description: Series of questions covering COVID-19 diagnosis and treatment, changes in myeloma treatment and care, clinical trial familiarity, health and fitness, and quality of life.
Study NCT05075499 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: COVID-19 vaccination
Description: Blood sample obtained before, 1 , 3 and 6 months after the intervention
Study NCT06415981 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hypoglossal nerve and/or Ansa Cervicalis stimulation
Description: Device stimulation of the hypoglossal nerve and/or Ansa Cervicalis
Study NCT05370963 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hylase versus dexmedtemodine
Description: fluroscopic guided lumber epidural injection
Study NCT05159492 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PVI using PEF
Description: PVI using PEF
Study NCT05159492 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PVI using CFRF
Description: PVI using CFRF
Study NCT05417269 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMCY-0141
Description: The investigational medicinal product (IMP) consists in a small synthetic peptide (23 amino acids - IMCY-0141) combining a known human epitope of MOG flanked with a thioredox motif, presented in the form of a freeze-dried sterile powder and diluent for subcutaneous (SC) administration. The diluent includes the adjuvant aluminium hydroxide (alum) at a concentration of 900 μg/mL. Treatment will be injected within 4h of resuspension of the powder with the diluent.~Treatment will consist of 6 immunizations (separated by 14 days) of the IMP by SC injection in the upper arm, in the region of the triceps (lateral part of the arm, midway between the elbow and the shoulder). Half of the dose to be administered will be injected concomitantly in both arms.
Study NCT05417269 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo will be administered by subcutaneous route, once every two weeks for 6 times. Placebo will be administered to patients randomized in the placebo group during Phase II only.
Study NCT05417269 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dimethyl Fumarate
Description: Dimethyl Fumarate (DMF) will be given orally, according to its SmPC for the whole duration of the study.~Dimethyl Fumarate (DMF) will be administered to patients randomized in the active control group during Phase II only.
Study NCT05801757 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remimazolam
Description: Using two different doses of remidazolam for continuous pumping to maintain anesthetic effect
Study NCT05801757 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: propofol 2-3mg/kg/h
Study NCT04867850 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Individual clinicians will receive an automated weekly email detailing a weekly roster of their upcoming repeat-patient visits (Index Visit) with patients at high risk of 6-month mortality as determined by a validated machine learning prognostic algorithm. Clinicians will receive a HIPAA compliant text message on the morning of the appointment reminding them to consider a serious illness conversation with patients on the list.
Study NCT04867850 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinician Nudge
Description: Clinicians will receive the usual care weekly email and text message described above under Usual Care. In addition, embedded in the weekly email, clinicians will receive performance feedback information detailing their documented SICs relative to those documented by peers.
Study NCT04867850 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Nudge
Description: Ahead of the Index Visit, high risk patients as identified by the prognostic algorithm will receive a nudge via personal text message and email consisting of a normalizing message prompting patients with a personalized link to a short electronic questionnaire on SIC topics.
Study NCT05340608 — intervention group
Intervention type: OTHER
Intervention: Smart, non-invasive shirt - Physiological parameters
Description: Observation Group One and Control Group - Participants in these groups will be asked to wear a smart, non-invasive shirt while watching two different five-minute videos. One video will show relaxing images and will emit relaxing music (relaxing video). The second video will present impressive human body deformities accompanied by anxious music (disturbing video). Both videos will be presented with the participant in a sitting position. The duration of the entire session will be approximately 15 minutes. For the whole duration of the session, the smart shirt will collect data on participants' physiological parameters (electrocardiogram, heart rate, heart rate variability, respiration rate, minute ventilation, and body movement). Collected data will be used to develop an ad-hoc algorithm to anticipate the challenging behavior of participants with autism spectrum disorder based on physiological data collected by the smart shirt.
Study NCT05340608 — intervention group
Intervention type: OTHER
Intervention: Smart, non-invasive shirt - Relation with challenging behaviors
Description: Observation Group Two - Each participant in this group will be asked to wear the smart, non-invasive shirt for seven consecutive days during waking hours, performing his usual daily activities. During the same seven days, the caregivers who care for the participant will be asked to accurately report the participant's status in a behavioral diary. Each evening, the data collected by the smart shirt will be uploaded to an online cloud along with the behavioral diary of the day. Collected data will be used to develop an ad-hoc algorithm able to anticipate the challenging behavior of participants with autism spectrum disorder based on physiological data collected by the smart shirt.
Study NCT05340608 — intervention group
Intervention type: OTHER
Intervention: Smart, non-invasive shirt - Proof of Concept
Description: Proof of Concept - The participant with autism spectrum disorder enrolled in the proof-of-concept phase of this study will wear the smart, non-invasive shirt for seven days during all hours of attendance at the special school. At the end of the seven days, the healthcare professional and teacher who interacted with the developed system at the special school will participate in a focus group to analyze their experiences and opinions related to the system use.
Study NCT05357677 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR419
Description: SR419 capsule
Study NCT05971485 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 10 mg
Description: Melatonin 10 mg will be used. 5 mg·kg-1 dissolved in 2 ml of distilled water via enteral route in one single dose 30 minutes before the venous cannula insertion
Study NCT05971485 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo group will receive 2 ml of distilled water as a placebo 30 minutes before venous cannula insertion.
Study NCT06329427 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dragon Ambient eXperience (DAX) Copilot
Description: The tool (DAX) listens to the conversation between a clinician and patient/caregiver during their visit, provides transcriptions between different speakers for the clinician to review, edit, and included in the final EHR notes.
Study NCT04765423 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: [F-18] NaF PET/CT
Description: Radiotracer F-18 NaF used on the PET/CT imaging
Study NCT04765423 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: [F-18] fluciclovine PET/CT
Description: F-18 fluciclovine (Axumin ®) used on the PET/CT camera
Study NCT03587831 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vertical Sleeve Gastrectomy
Description: Surgical Procedure: Vertical Sleeve Gastrectomy
Study NCT03587831 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle Modification Counseling
Description: Behavioral Intervention: Lifestyle Modification Counseling
Study NCT03587831 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Modification Counseling
Description: Behavioral Intervention: Lifestyle Modification Counseling
Study NCT05980364 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Technology-based training structured according to the Health Promotion Model
Description: Experimental group: A video recording was created with a total of 6 zoom applications to be shared with the patients. The content of the video recordings consists of a presentation accompanied by a slide show with open-ended questions prepared by considering the basic concepts of the trainings and the Health Promotion Model. Video recordings, each of which lasted approximately 15-25 minutes, were shared with patients once a week for a total of 6 weeks via WhatsApp. After each video, patients were given three days to watch the video recordings and create their own responses. After this three-day period, the researcher called the patients with whom he shared the content and gave counseling for 10-15 minutes and received feedback. Follow-up was done in the second 6-week period. During the monitoring process, two reminder interviews were made over the phone, with an interval of 2 weeks, for reminder and counseling, and the post-test data were collected at the end of the monitoring period.
Study NCT06357871 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT04480190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: IV Gemcitabine 1000mg/m2 to be given on Days 1, Day 8 (Before Cisplatin); 3 week cycles
Study NCT04480190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: IV Cisplatin 25mg/m2 to be given on Days 1, Day 8
Study NCT04480190 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Infusional 5-FU 225 mg/m2/d via Continuous IV infusion, to be given Days 1-5 and 8-12 during RT
Study NCT04480190 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Short course ChemoRT
Description: Radiation Therapy:~Sim: All patients will undergo 4D-CT simulation with 3 hours fasting with or without IV contrast. Compression may be used depending on the tumor motion.~Radiation Target Volume: The gross tumor volume (GTV) will be defined on all relevant imaging datasets including diagnostic CT, MRI, MRCP and/or ERCP data. An iGTV will be generated using the 4D datasets. The clinical target volume (CTV) will include the entire iGTV as well as portal lymphatic and celiac nodal space for all patients with selective treatment of the SMA and pancreaticoduodenal depending on the tumor location. A 5 mm margin will be added to the CTV to generate the planning target volume (PTV).~Radiation Dose: The dose will be 30 Gy in 10 fractions (3 Gy per fraction) for all patients using either 3D Conformal or Intensity Modulated Radiation Therapy techniques.
Study NCT04732130 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Time-Restricted Feeding
Description: Participants are instructed to limit food intake to maximum 8 hours per day.
Study NCT04732130 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Alternate Day Fasting
Description: Participants are instructed to fast every other day.
Study NCT05041595 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Lyme diagnostic assay
Description: Serological and immunoresponse assay
Study NCT06089213 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: real-time intervention
Description: An individual exercise program will be carried out at home, supervised remotely via videoconference.
Study NCT06089213 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: real-time intervention
Description: An individual exercise program will be carried out at home, supervised remotely via videoconference.
Study NCT05077995 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Polar M200
Description: Participants will have to wear the activity monitors (AP and Polar M200) for at least 7 days. Minutes spent in each activity type will be summed to a total day score. Participants will be instructed to do their regular daily life activities without limitation, but to note their main activity categories in an activity diary, with a main focus on cycling and participation in structured exercise.
Study NCT05105282 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Two different blocks with same local anesthetic volume
Description: Deep serratus anterior block and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.
Study NCT05848700 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SEP-363856
Description: SEP-363856 Tablet
Study NCT05848700 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo Tablet
Study NCT05440669 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: white noise
Description: white noise will reduce pain and stress in nasal cpap application
Study NCT04821674 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DS-5670a
Description: DS-5670a (10, 30, 60 or 100 µg) administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total
Study NCT06167044 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: thoracic mobilization
Description: Thoracic mobilization will be performed for the thoracic spine mobilization group, thoracic mobilization therapy will be performed for five minutes.
Study NCT04821674 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered as an intramuscular injection into the deltoid muscle of the upper arm; 2 injections total
Study NCT05679544 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Characterization of early biological effects following exposure to PAHs
Description: Biological samples collected in period of exposure and after holidays
Study NCT05800028 — intervention group
Intervention type: BEHAVIORAL
Intervention: Learning new information
Description: The purpose of this study is to test the effects of different social contexts when learning new information. Participants in the AD, SPPA, and HC experimental groups will be given tests to learn verbal information (location of drawings in a grid). The learning phases of these tests are presented in the form of a memory game in which participants are asked to make pairs of drawings by finding the second copy of the proposed pair by trial and error in a grid. After learning, a task of recognizing the position of the drawings in the grid is performed. Each participant will carry out this learning in three different conditions: 1) learning alone, 2) learning by observation of the reconstruction of the pairs of images by a partner, and 3) collaborative learning in which the two game partners discover and reconstruct the pairs together.
Study NCT05993780 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: No drugs or biologial agents were used in our trial
Description: Before the measurement, a recruitment maneuver was performed for 30-40 s at a PEEP level of 20 cmH2O. At four different PEEP levels of 15, 10, 5, and 0 cmH2O, a decreasing PEEP trial was performed, and the measurement results were recorded.The measurement time at each PEEP level was chosen as 10 minutes. At the end of the measurement, static compliance was measured by applying an end-inspiratory pause. Respiratory system elastance,static strain volume gain was calculated.The estimated lung volume recovered was calculated using the formula ∆EELV - (∆PEEP x Compliance PEEPlow) and compared with the volume gain.
Study NCT06164223 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VR Baby Pump
Description: VRBaby-Pump application is a video application specially prepared with virtual reality glasses and a milking pump placed inside a toy doll. In the video content, the mother is breastfeeding her baby on an armchair in the baby room prepared for a newborn baby.
Study NCT06255314 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ventral hernia repair
Description: Laparoscopic transabdominal retromuscular repair is a minimally invasive approach to the open Rives Stoppa retromuscular sublay repair for ventral hernia.~In ventral hernia repair, it relies on initiation of dissection in one retrorectus space and then crossover to the contralateral retrorectus space The sublay mesh technique is an open surgical procedure for ventral and incisional hernias
Study NCT05898555 — intervention group
Intervention type: DEVICE
Intervention: Skiin garment and pods
Description: Participants will be asked to wear a Skiin smart garment over their own clothes.~Small motion capture markers will be placed on their body and pressure-sensitive insoles placed into their shoes to measure the pressure underneath their feet during the study tasks.~Once the sensors are ready for collection, participants will be asked to complete 5 tasks associated with their daily activities: 1. Locomotion; 2. Lower limb strength - repeated sit-to-stand-to-sit transitions; 3. Lower limb strength and locomotion - Timed Up and Go; 4. Free walking during a 2min walk; 5. Standing balance, postural control.
Study NCT05941338 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirelizumab ,+Carboplatin+albumin-bound paclitaxel
Description: Sintilimab (IV), dose= 200mg , day=1 , cycle length: 21 days. Carboplatin (IV), dose=300mg/m2, day= 1, cycle length: 21 days. albumin-bound paclitaxel (IV), dose=260mg/m2, day= 1, cycle length: 21 days. Intervention: Drug: Sintilimab , Carboplatin, albumin-bound paclitaxel
Study NCT06125587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chiglitazar
Description: Chiglitazar is a novel PPAR agonist. Treatment of type 2 diabetes mellitus by moderate activation of PPARα, PPARγ and PPARδ, improving insulin sensitivity, regulating blood glucose, and promoting fatty acid oxidation and utilization.
Study NCT06125587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Metformin is not only an antihyperglycemic drug, it also corrects insulin resistance and hyperandrogenism in polycystic ovary syndrome.
Study NCT05528679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 610 100mg
Description: 100mg administered subcutaneously Q4W
Study NCT05528679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 610 300mg
Description: 300mg administered subcutaneously Q4W
Study NCT05528679 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: administered subcutaneously Q4W
Study NCT05527145 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimally invasive surgery
Description: Surgery with decompression. Central decompression of the stenotic segment with undercutting of the lateral recesses.
Study NCT05527145 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous Spacer
Description: percutaneous image guided outpatient procedure that enables interspinous spacer insertion and fusion
Study NCT06305715 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radiation Therapy
Description: Enrolled subjects will be given radiation doses, at the discretion of the treating physicians, that range from 24-60 Gy in 1-15 fractions with a minimum biologically effective dose (BED\^10) of 58 Gy.
Study NCT06305715 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Targeted TKI therapy
Description: Immediately following radiation therapy, subjects with an actionable driver mutation will receive a standard-of-care TKI. The choice of TKI will be at the discretion of the treating oncologist.
Study NCT00858741 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: single fraction
Description: 8 Gy x 1 fraction to 8 Gy total dose in single dose.
Study NCT00858741 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: multiple fractions
Description: 3.0 Gy x 10 fractions to 30.0 Gy total dose in two weeks.
Study NCT06537557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the early in-hospital temperature management protocol for heat stroke patients
Description: The early in-hospital temperature management protocol for heat stroke includes early identification, selection of cooling methods for rapid cooling, precise target temperature management, and dynamic monitoring. Effective temperature management will be implemented for heat stroke patients to improve their outcomes.
Study NCT05249673 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: global postural reeducation
Description: GPR interventions will last 9 sessions, 1 hour each, with one-to-one supervision, once or twice a week according to the participant's needs. All participants will receive advice to follow written ergonomic suggestions and to repeat the exercises in the first physical therapy session at home twice a week for 15 minutes. Each group will get a home exercise program, which will differ according to the type of treatment received. Participants in the GPR group will execute one posture routine.