AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06606275 — intervention group
Intervention type: DRUG
Intervention: Warfarin
Description: Warfarin is a vitamin K antagonist widely used as an anticoagulant to prevent thromboembolic events, particularly in conditions like atrial fibrillation, venous thromboembolism, and in patients with mechanical heart valves. It inhibits the enzyme vitamin K epoxide reductase, thereby reducing the activation of vitamin K-dependent clotting factors (II, VII, IX, X) and regulatory proteins C and S. Due to its narrow therapeutic index, warfarin requires regular monitoring of the International Normalized Ratio (INR) to optimize anticoagulation while minimizing the risk of bleeding. Warfarin's pharmacokinetics and pharmacodynamics can be influenced by genetic polymorphisms, diet, and drug interactions, necessitating individualized dosing strategies.
Study NCT06637332 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin (IV)
Description: Vancomycin by injection to be given at a dose selected by the treating team to achieve a desired trough level or AUC-based target, as determined by local standards of care
Study NCT04913220 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THOR-707
Description: Solution for infusion: intravenous infusion
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin 2.5 mg/kg (8 weeks)
Description: 2.5 mg/kg IV Belantamab mafodotin IV every 8 weeks for Part 1
Study NCT04913220 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Solution for infusion: intravenous infusion
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin 1.9 mg/kg (8 weeks)
Description: 1.9 mg/kg IV Belantamab mafodotin IV every 8weeks for Part 1
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin 1.4 mg/kg (12 weeks)
Description: 1.4 mg/kg Belantamab mafodotin IV every 12 weeks for Part 1
Study NCT06437353 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: First-line chemotherapy regimen:~* Paclitaxel: 175 mg/m², intravenous infusion, on day 1.~* Carboplatin: AUC 5, intravenous infusion, on day 1.~* Surufatinib：250 mg once daily, taken continuously.~Maintenance Therapy Regimen:~* Surufatinib: 250 mg once daily, taken continuously.~* Olaparib: 300 mg twice daily.
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin 1.9 mg/kg (12 weeks)
Description: 1.9 mg/kg Belantamab mafodotin IV every 12 weeks for Part 1
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin every 4 weeks, 6 weeks,8 weeks, or 12 weeks as determined by Part 1 recommended dosages
Description: Belantamab mafodotin Dose 1.0 mg/kg, 1.4 mg/kg, 1.9mg/kg or 2.5mg/kg every 4 weeks, 6 weeks, 8 weeks or 12 weeks as determined by Part 1 recommended dosages.
Study NCT05145816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belantamab mafodotin 1.0 mg/kg (12 weeks)
Description: 1.0 mg/kg Belantamab mafodotin IV every 12 weeks for Part 1
Study NCT05766280 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iCareer Soft Skills Training for Employment
Description: The telehealth iCareer intervention will be delivered during regular educational or vocational services (i.e., services from the Office of Disability Services (ODS) and/or from the school or college counseling center). Six modules of Soft Skills Training (SST), four group sessions for each module with 60 to 90 min for each session (depending on group size) will be delivered by trained project staff (graduate counseling student assistant or graduate counseling intern) via HIPAA-compliant Zoom videoconferencing. If participants are unable to join by Zoom videoconferencing, telephone (a format widely used in Cognitive Behavior Therapy (CBT) for Post Traumatic Stress Disorder (PTSD) treatment delivery and in CBT for depression) will be utilized. Ethical guidelines for providing telehealth over videoconferencing or phone will be followed.
Study NCT06673641 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2%
Description: The study medication was applied once daily to cover the entire face after washing, avoiding the eyes, lips, angles of the nose, and mucous membranes for 84 consecutive days.
Study NCT06673641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: CABTREO Topical Gel
Description: The study medication was applied once daily to cover the entire face after washing, avoiding the eyes, lips, angles of the nose, and mucous membranes for 84 consecutive days.
Study NCT06673641 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: The study medication was applied once daily to cover the entire face after washing, avoiding the eyes, lips, angles of the nose, and mucous membranes for 84 consecutive days.
Study NCT06675786 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: I.V. House UltraDressing
Description: I.V. House UltraDressing (I.V. House, Inc., St. Louis, MO, USA) will be applied according to the manufacturer's instructions and secured with an anti-slip tape without the need for further taping. It is intended to prevent complications such as catheter-related displacement, phlebitis, infiltration, extravasation, catheter occlusion, and folding of PVCs.
Study NCT06673940 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical nerve stimulation (TENS)
Description: TENS is applied on the acupuncture points Intervention arm
Study NCT06673940 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Therapy program
Description: Physical therapy methods
Study NCT06673914 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Group: Diet Group
Description: Patient in Diet Group and Oleuropein and Diet Group will be given a personalized diet and be followed up by a dietician.
Study NCT06673914 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control Group: Diet Group
Description: Patient in Diet Group and Oleuropein and Diet Group will be given a personalized diet and be followed up by a dietician.
Study NCT06673914 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oleuropein and Diet Group
Description: Dietary Supplement: Oleuropein (Olive Leaf Extract) Patients in Oleuropein and Diet Group will receive 200 mg/day oleuropein supplement and personalized diet followed up by a dietician.
Study NCT06508944 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: vaginal 17 beta-estradiol
Description: * Femiest® Haupt Pharma Munster GMBH, Muenster, Germany~* The assigned dosage will be one vaginal tablet daily for two weeks then one vaginal tablet twice a week for 10 weeks.
Study NCT06508944 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: * Placebo is produced by Chulalongkorn University Drug and Health Products Innovation \& Promotion Center.~* The assigned dosage will be one vaginal tablet daily for two weeks then one vaginal tablet twice a week for 10 weeks.
Study NCT06673836 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DYNAMIC CYCLING
Description: Balance Training: Exercises focused on improving coordination and balance, such as standing on one leg, walking on uneven surfaces, or using balance boards.~Core Strengthening: Strengthening core muscles helps children maintain stability during dynamic movements, such as walking or running.~Proprioceptive Training: Exercises that improve awareness of the body's position in space, such as obstacle courses or activities that challenge movement coordination.
Study NCT06673836 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: INCLINED TREAD MILL
Description: Dynamic Cycling: Refers to the fluctuating nature of movement patterns, often used in therapies like stationary biking or recumbe.nt cycling, where the intensity and resistance vary. Dynamic cycling can also refer to training that involves alternating between high and low-intensity phases or cycling between different positions (sitting, standing) or speeds during the activity
Study NCT06675409 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: The effectiveness of two different training methods with virtual patients for improving the critical decision-making skills of paramedic students will be compared between two groups: one receiving expert-guided training and the other following a self-directed approach
Study NCT06508944 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral modifications
Description: Behavioral modifications for women with storage symptoms of lower urinary tract symptoms (LUTS) involve strategies such as regulating fluid intake, avoiding bladder irritants, practicing bladder training techniques (scheduled and delayed voiding), performing pelvic floor muscle exercises, managing weight, increasing dietary fiber, maintaining a bladder diary, setting a regular voiding schedule, utilizing stress management techniques, and educating patients about LUTS.
Study NCT06508944 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Behavioral modifications
Description: Behavioral modifications for women with storage symptoms of lower urinary tract symptoms (LUTS) involve strategies such as regulating fluid intake, avoiding bladder irritants, practicing bladder training techniques (scheduled and delayed voiding), performing pelvic floor muscle exercises, managing weight, increasing dietary fiber, maintaining a bladder diary, setting a regular voiding schedule, utilizing stress management techniques, and educating patients about LUTS.
Study NCT06028347 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sa-mRNA vaccine Dose 1
Description: self-amplifying mRNA vaccine
Study NCT06675409 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: The effectiveness of two different training methods with virtual patients for improving the critical decision-making skills of paramedic students will be compared between two groups: one receiving expert-guided training and the other following a self-directed approach
Study NCT06674265 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Allogenic NK cells infusion
Description: Natural Killer (NK) cells are extracted from a healthy donor through apheresis and processed in a clean room using the CLINIMACS device. After quality assessment, these cells are stored at -198°C until needed. When required, the cells are thawed, washed, and evaluated for viability and sterility before being administered to the patient at a dosage of 5 × 10\^6 cells per kilogram of body weight. Two further injections may be considered based on the patient's response and confirmed improvement via MRI MIBG. Injections are scheduled seven to ten days after each chemotherapy course according to the standard treatment protocol.
Study NCT06609304 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Axicabtagene Ciloleucel
Description: Axicabtagene Ciloleucel at 2.0×10\^6/Kg
Study NCT05257837 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Debriefing
Description: Children and their parents will be debriefed on the actual purpose of the study, including the role of the safety video and how the movie clips were edited.
Study NCT06674343 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furmonertinib
Description: Furmonertinib 160mg, once daily, orally. Other Names: AST2818
Study NCT06028347 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sa-mRNA vaccine Dose 2
Description: self-amplifying mRNA vaccine
Study NCT06028347 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: sa-mRNA vaccine Dose 3
Description: self-amplifying mRNA vaccine
Study NCT06028347 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Saline for injection
Study NCT05154487 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alpelisib Pill
Description: Kinase inhibitor
Study NCT05154487 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fulvestrant injection
Description: estrogen receptor agonist
Study NCT06536608 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: The Oketani Method is based upon practical breastfeeding theory, but is original in its practice. Oketani breast massage improves breastmilk secretion, can prevent and treat problems such as mastitis. In addition, the massage is painless, allowing your body to relax and breathe, something very much appreciated by mothers.~The Oketani breast massage consists of massaging and milking the base of the breasts. These delicate glands are massaged as well as protected.
Study NCT05257837 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Debriefing
Description: Children and their parents will be debriefed on the actual purpose of the study, including the role of the safety video and how the movie clips were edited.
Study NCT06673784 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ophthalmic saline eye drops
Description: for optical examination
Study NCT06673784 — intervention group
Intervention type: DRUG
Intervention: Saline
Description: Most one natural and not effects on study
Study NCT06673459 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: TBICy
Description: The TBI-Cy group was administered 250 mg/m2/d oral Me-CCNU on day -8. A total of 12 Gy TBI was for each patient and fractionated dose was 2 Gy twice daily or 4Gy once daily on days -8 to -6. Occluding of the lung fields during TBI, the corresponding irradiation dose reduced to a total of 8 Gy. On day -5, the schedule was intravenous 2 g/m2 Ara-C every 12 hours. Then intravenous 1.8 g/m2 CTX once per day from days -4 to -3.
Study NCT06673459 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: BuCy
Description: The BuCy group received oral Me-CCNU 250 mg/m2/d twice daily on day -8, intravenous cytosine arabinoside (Ara-C) 2 g/m2 twice daily on day -7, intravenous Bu 3.2 mg/kg/d from days -6 to -4, and intravenous cyclophosphamide (CTX) 1.8 g/m2/d from days -3 to -2. There were no patients accepted oral Bu.
Study NCT06684652 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 3TB+6SB
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position or lithotomy position. The ultrasound equipment used included a color Doppler ultrasound diagnostic instrument (Hitachi HiVision, Philips Epiq 7), transrectal probes, and corresponding puncture needle guns. Color Doppler examination was performed from the base to the apex. For each predefined mpMRI suspicious lesion, urologists firstly obtained three-core TB from the lesion within the mpMRI suspicious lesion. Then urologists obtained sextant six-core SB. Each core was placed in an individual container and reported separately in accordance with the Ginsburg scheme. Histology was evaluated by senior uropathologists who were blinded to the imaging findings.
Study NCT06684652 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 3TB+12SB
Description: The biopsy procedure was conducted by a highly skilled and experienced urologist who specializes in performing prostate biopsies. Prophylactic antibiotics were routinely used both before and one day prior to scheduled surgery. Each patient was placed in the left lateral position or lithotomy position. The ultrasound equipment used included a color Doppler ultrasound diagnostic instrument (Hitachi HiVision, Philips Epiq 7), transrectal probes, and corresponding puncture needle guns. Color Doppler examination was performed from the base to the apex. Urologists firstly obtained three-core TB from the lesion within the mpMRI suspicious lesion. Then urologists obtained fore-zone 12-core SB. Each core was placed in an individual container and reported separately in accordance with the Ginsburg scheme. Histology was evaluated by senior uropathologists who were blinded to the imaging findings.
Study NCT06690879 — intervention group
Intervention type: DEVICE
Intervention: Smartphone application AI Posture Evaluation and Correction System (APECS)
Description: Mobile application APECS v. 6.2.0. is used to assess upper body posture during standing from back side and right side.
Study NCT06690320 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IMPLEMENTATION OF A PLANNED EDUCATION PROGRAM ON HEALTH BELIEF MODEL AND FATUALIST TENDENCIES IN WOMEN AT HIGH RISK OF BREAST CANCER
Description: Description: By examining the parameters of the health belief model and fatalism scales, 6 targets were determined for these scale parameters. The targets were prepared to gain early diagnosis behaviors in breast cancer. By using the breast model, the behavior will be demonstrated in practice
Study NCT06688864 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EPIO App
Description: Participants will receive access to the app-based cognitive-behavioral pain self-management intervention program (EPIO) for 3 months.
Study NCT06691594 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: neoadjuvant SBRT combined with PD-1 monoclonal antibody and chemotherapy
Description: Eligible participants will receive neoadjuvant treatment consisting of:~SBRT: One session of 10Gy radiation to the primary tumor, followed by a 150mg subcutaneous injection of pembrolizumab (PD-1 inhibitor).~Chemotherapy and Immunotherapy: One week after SBRT, participants will undergo 6 cycles of pembrolizumab (400mg), albumin-bound paclitaxel (250mg/m²), and carboplatin (AUC=5).~Surgery: Surgery will be performed 21 days after the last chemotherapy cycle, with either breast-conserving surgery or modified radical mastectomy. Pathological evaluation will assess the treatment response.~Adjuvant Immunotherapy: Four weeks post-surgery, patients will receive pembrolizumab every 3 weeks for up to 1 year.
Study NCT06691542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: platelet-rich plasma
Description: platelet-rich plasma, metformin and cryotherapy in treatment of non-genital warts
Study NCT06691542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: platelet-rich plasma, metformin and cryotherapy in treatment of non-genital warts
Study NCT06691542 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cryotherapy
Description: platelet-rich plasma, metformin and cryotherapy in treatment of non-genital warts
Study NCT06688461 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental group: Exercise training
Description: HIIT program, 3 times per week for 12 weeks
Study NCT06693947 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Alpine dairy products
Description: The intervention group will be instructed to eat three portions of alpine dairy products daily. The proposed three portions represent an estimated mean consummation in the study population, taking into consideration the national statistics.
Study NCT05476822 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Obtain antibody titers
Description: Obtain blood samples for antibody titers at the time of enrollment, at three months, six months and nine months post vaccine booster (+/- ten days).
Study NCT06695663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Referral and communication skills learning
Description: assigned to receive a brief, live, experiential training on the referral process and communication strategies.
Study NCT06695663 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Written guide to the referral process
Description: assigned to receive only written information about the referral process
Study NCT06695663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empowered Generations (eGen): parent training
Description: eGen is a six-session parent training program provided by therapists via video chat online to parents with a child between the ages of 3-8 years.
Study NCT06695663 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: control
Description: The control condition consists of a single scripted session, in which therapists guide the parent to the following resources: (a) a book, Raising Cooperative Kids, by GenPMTO co-developer Marion Forgatch; (b) vetted parenting advice websites; (c) information about Early Childhood and Family Education classes, which are provided for free in Minnesota through public schools; and (d) a list of culturally tailored parenting advice websites.
Study NCT06687421 — intervention group
Intervention type: OTHER
Intervention: High-risk treatment SOC
Description: radiotherapy (RT) + ADT (3 years) + Abiraterone acetate (2 years), with radical prostatectomy being an option if contraindication for RT exists)
Study NCT04976023 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Yupingfeng Powder granules
Description: 14.5 5 g twice daily for 8 weeks
Study NCT06687421 — intervention group
Intervention type: OTHER
Intervention: Active monitoring
Description: Followed with PSA measurements
Study NCT05008185 — intervention group
Intervention type: PROCEDURE
Intervention: Regenerative Peripheral Nerve Interface (RPNI) surgery
Description: Surgeons will perform neuroma resection and RPNI creation using a free muscle graft from the brachioradialis muscle harvested through a small separate incision
Study NCT05008185 — intervention group
Intervention type: PROCEDURE
Intervention: Traction Neurectomy
Description: Surgeons will perform neuroma resection and traction neurectomy,