AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05430035 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HIPEC
Description: Heated Intra-Peritoneal Chemotherapy (HIPEC) HIPEC will be performed at the time of the index operation if a cancer is known pre-operatively, at the time of re-operation for incidentally discovered cancers already treated with cholecystectomy that are undergoing central hepatectomy and portal lymphadenectomy as part of standard of care, or independently if no other procedures are indicated. A closed technique will be utilized to deliver mitomycin C (MMC) over the first 60 minutes followed by an additional smaller dose over an additional 30 minutes. Perfusate will be heated to obtain a tissue temperature of 42°
Study NCT04599634 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magrolimab
Description: Administered intravenously, starting at 1 mg/kg on second day of first cycle then 30mg/kg on days 8, 15 and 22 of cycle 1 and days 1 and 15 of cycles 2-12 for patients in both the dose finding and expansion phases.
Study NCT05491668 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Non-hyperemic pressure ratio assessment pre and post PCI
Description: Pre and post PCI invasive physiologic assessment
Study NCT06136585 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 2 mg/kg sugammadex
Description: All participants will be given rocuromium for neuromuscular blocks during the procedure. Per randomization, patients in this group will be reversed with 2 mg/kg sugammadex.
Study NCT06136585 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.07 mg/kg neostigmine
Description: All participants will be given rocuromium for neuromuscular blocks during the procedure. Per randomization, patients in this group will be reversed with 0.07 mg/kg neostigmine (to a maximum of 5 mg).
Study NCT04981535 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Head box during upper gastrointestinal endoscopy
Description: ็Head box is an acrylic box over a patient's head who undergoing upper gastrointestinal endoscopy.
Study NCT04852107 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Spinal Cord Stimulation, association of both (DUAL), Dorsal Root Ganglion stimulation
Description: Lead Implantation which will be conducted in 2 steps:~1. Lead implantation: 8-contact SCS percutaneous lead on SC and 8-contact lead on DRG.~2. Neurostimulation trial phase (Mode DUAL). IPG implantation + Randomization + 1st leads programming (SC, DRG or DUAL stimulation according to randomization sequence).~2nd leads programming (SC, DRG or DUAL stimulation according to randomization sequence). 3rd leads programming (SC, DRG or DUAL stimulation according to randomization sequence). All patients will be switched to Burst waveform for a 1- month follow-up period while keeping the last allocated stimulation type in the randomized crossover arm.
Study NCT05241613 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AC176
Description: AC176 will be given orally (PO) on a 28-day cycle.
Study NCT04908618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: digital impression for normal abutment
Description: Accuracy of scan body impression
Study NCT04908618 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: open tray impression
Description: Accuracy of open tray impression
Study NCT04908618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: open tray impression
Description: Accuracy of open tray impression
Study NCT04908618 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: closed tray impression
Description: Accuracy of closed tray impression
Study NCT06251882 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: injection
Description: 10ml D5W injection for MP patients
Study NCT05666427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor muscle training combined with stabilization exercises
Description: While people are doing stabilization exercises, they will also work the pelvic floor muscles. Practices will be combined with breathing.
Study NCT04908618 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: closed tray impression
Description: Accuracy of closed tray impression
Study NCT05666427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor muscle training
Description: Exercises that activate the pelvic floor muscles to strengthen and increase endurance.
Study NCT05389163 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Giomer based injectable resin composite
Description: Giomer material has been introduced as the true hybridization of glass ionomer and resin composite, containing surface pre-reacted glass ionomer (S-PRG) filler particles within a resin matrix. Giomer combines caries protection through fluoride release and recharge of glass ionomers and the esthetics, physical and handling properties of resin composite
Study NCT05389163 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Resin modified glass ionomer
Description: Resin modified glass ionomer (RMGI) have been developed to combine the advantages of both resin composite and glass ionomer; the good mechanical properties, esthetic of resin composite added to anticariogenic activity and chemical bonding to tooth structure of glass Ionomer.
Study NCT05291494 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: follow the WeChat public platform to watch the education videos
Description: In addition to the regular preoperative visits, the WeChat education group will watch science videos through WeChat before the surgical procedures.
Study NCT05291494 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: regular preoperative visits and education by ward nurses.
Description: received oral instruction from the ward nurse covering the same contents as above instead of the education video.
Study NCT06077266 — intervention group
Intervention type: OTHER
Intervention: Change of weight class to normal weight
Description: The exposure is the change of weight class from obesity to normal weight during a follow-up period without known intervention.
Study NCT05649501 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Proprioceptive neuromuscular facilitation techniques.
Description: Proprioceptive neuromuscular facilitation stretching which include hold-relax and contract-relax for 6 sec hold, 10 repetitions and 2 min rest in between, for 5 day/week for 4 weeks along with conventional treatment for 40 minutes.
Study NCT05540587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Edoxaban
Description: Patients in the Edoxaban group take Edoxaban 60mg once daily. If any of the following conditions are present, take 30mg once daily.~* CrCl 15-50mL/min~* Body weight ≤ 60kg~* Concomitant use of P-glycoprotein inhibitor (Dronearone, Ciclosporine, Erythromycin or Ketoconazole)
Study NCT05540587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Warfarin
Description: Patients in the Warfarin group take Warfarin 2-10mg once daily, dose adjusted with the target INR 2-3. In the elderly or frail patients, a lower dose administration is allowed at the discretion of the investigator.
Study NCT06067737 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Psilocybin
Description: High-dose psilocybin (30 mg) session will be administered following standard-of-care outpatient buprenorphine induction to evaluate its effect on drug abstinence, quality of life, craving, tobacco use, and treatment retention in healthy participants with an active OUD diagnosis.
Study NCT06067737 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Psilocybin
Description: A very low dose (1 mg) psilocybin session following standard-of-care outpatient buprenorphine induction will be used as a comparator arm to the high-dose psilocybin arm in evaluating psilocybin's effect on drug abstinence, quality of life, craving, tobacco use, and treatment retention in healthy participants with an active OUD diagnosis.
Study NCT05490550 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: COAST-enhanced CBTI
Description: Participants will receive CBTI delivered through the COAST platform by one of NOCTEM's certified and licensed COAST clinician. Communication between the participant and licensed clinician will occur primarily through COAST's HIPAA-compliant text messaging, but clinicians and patients may elect to connect via telephone calls or HIPAA-compliant secure videoconference if needed.
Study NCT05490550 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Military Treatment Facility Insomnia Care As Usual
Description: Participants will receive the insomnia care offered at their site following current delivery practices (i.e., face-to-face or virtual; individual or group format). During the treatment phase, participants randomized to ICAU will be instructed to communicate with their clinicians as needed, according to standard procedures in place.
Study NCT05562375 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GOCCLES
Description: Inspection using GOCCLES®. An UV light source will be administered, with polymerization lamp sdi radii xpert, with a potency of 1500 mW/cm2 and a wavelength of 440-480nm, applied at 20cm of the injury.~Notes will be taken on the location and size of the injury observed with the device.~Image register using the GOCCLES® photographic filter for mobile devices. The same light source will be used.
Study NCT05562375 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Toluidine blue stain
Description: To value the toluidine blue diagnosis capacity, the sequence described by Mashberg will be followed: The patient will realize a mouthwash with acetic acid at 1% for 20 seconds. Two using water for 20 seconds. Toluidine blue at 1% will be applied for 20 seconds. New mouthwash with acetic acid for 60 seconds and a final mouthwash with water.~Notes on the and pictures will be taken on the location and size of the injury.
Study NCT05649501 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Proprioceptive neuromuscular facilitation techniques.
Description: Proprioceptive neuromuscular facilitation stretching which include hold-relax and contract-relax for 6 sec hold, 10 repetitions and 2 min rest in between, for 5 day/week for 4 weeks along with conventional treatment for 40 minutes.
Study NCT05649501 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Traditional physical therapy
Description: Conventional therapy (ROMs, stretching, strengthening) of lower limbs for 40 minutes.
Study NCT04595890 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Arthrex Angel System used to prepare injection of Bone Marrow Concentrate (BMC)
Description: Participants will have bone marrow aspirated from their iliac crest, then processed using the Arthrex Angel System to produce autologous bone marrow concentrate (BMC). Then, BMC will be injected into the participant's knee with knee osteoarthritis (OA).
Study NCT04595890 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline injection
Description: Participants will have bone marrow aspirated from their iliac crest to maintain masking. Then, saline will be injected into the participant's knee with knee osteoarthritis (OA).
Study NCT05002751 — intervention group
Intervention type: OTHER
Intervention: UCSD Vaginal Dilator Questionnaire
Description: 14 question survey
Study NCT05002751 — intervention group
Intervention type: OTHER
Intervention: EORTC Sexual Health Questionnaire
Description: 22 question survey
Study NCT05562375 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: The area to biopsy will be chosen, and, using local anaesthesia, it will be resected. The specimens will be sent to the oral and maxillofacial pathology diagnostic service of the University of Basque Country for anatomopathological study
Study NCT06426355 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: NMN
Description: NMN capsules (total of 600mg/day) for 2-5 months
Study NCT06426355 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: NMN-free placebo capsules for 2-5 months
Study NCT06122311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N Acetylcysteine
Description: N-acetylcysteine sachets 600 mg twice daily
Study NCT05369182 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Invasive physiologic assessment
Description: All coronary physiologic parameters are measured following diagnostic angiography. Resting pd/pa, FFR, CFR and IMR will be calculated using coronary physiologic parameters.~In patients treated by PCI, post-PCI physiologic assessment including CFR, IMR, and FFR will be performed.
Study NCT05369182 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Intravascular imaging
Description: By the operator's discretion, stent-optimization will be performed under intravascular imaging devices (IVUS \[Boston Scientific, Natick, Massachusetts, USA\] or OCT \[Abbott Vascular\], St. Paul, MN, USA\]).
Study NCT05237375 — intervention group
Intervention type: OTHER
Intervention: The MIDWIZE model
Description: So-called MIDWIZE ambassadors are planned to be appointed to lead the clinical implementation of the quality improvement components.~Initial training workshops will be held with the ambassadors on practical aspects of the chosen components and how to explain their benefits to the units' staff. Training will also be provided on how to enhance interdisciplinary teamwork and coordinate quality improvements. The workshops will be held onsite at Naguru hospital and online via the project's MIDWIZE virtual platform. The ambassadors will themselves hold training workshops to support midwives and other healthcare providers at the clinics during the implementation of the quality improvements components. The virtual MIDWIZE platform will contain videos, posters, presentations, and other training material that the ambassadors can utilise to enhance the units' capacity and engage their colleagues.
Study NCT05626270 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: LunulaLaser OTC
Description: The LunulaLaser™ OTC is a nonthermal and non-invasive procedure designed to restore the growth of clear, healthy nails in clients with onychomycosis.
Study NCT06424184 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accelerated Repetitive Transcranial Magnetic Stimulation
Description: The rTMS protocol implemented in this study will include approximately 10-minute long sessions of intermittent theta burst stimulation (iTBS) with at least 50 minutes in between iTBS sessions.~Study participants will receive the rTMS intervention for up to 50 sessions across a three-week period. The total of 50 sessions will be administered as up to 4 sessions each day, up to 5 days per week over an up to 3-week-long period.
Study NCT05087550 — intervention group
Intervention type: PROCEDURE
Intervention: Liver Transplantation
Description: Patients who underwent liver transplantation at Methodist Dallas Medical Center
Study NCT06490835 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-quality palliative care through consultation-based palliative care services in the ICU
Description: Family Counseling: Social workers implement a supportive process for families, assessing the individualized psychosocial and decisional support needs of patients and families to provide foundational data for palliative care consultations.~Family Meeting Support: In cases of high medical complexity, uncertainty, value conflicts, or communication issues, the palliative care consultation team supports the facilitation of family meetings.~Consultation: The palliative care team provides consultations to the attending physician based on the palliative care needs assessed during family counseling. Topics include symptom management, understanding treatment options, decisional conflict, emotional and practical support, goal of care setting, resources, and bereavement support.~Palliative Care by attending Physician: The attending physician incorporates the consultations received from the palliative care consultation team to provide high-quality palliative care to patients and their families.
Study NCT06004843 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: remimazolam
Description: in this group,patients are treated with remimazolam and remifentanil for reduced sedation.
Study NCT06004843 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: in this group,patients are treated with propofol and remifentanil for reduced sedation.
Study NCT05998421 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: The patients in the acupuncture group accepted acupuncture treatment weekly from the second day of menstruation and three times in one cycle. Seirin 0.2-×30-mm acupuncture needles were used. First, needles were inserted into Shenting (GV 24) and bilateral Benshen (G 13) to relieve uneasiness of mind. Then, they were inserted into Chung wan (cv 12), Qihai (CV6), Guan yuan, chung chi (cv 3), bilateral Guiai (S 29) and Zigong (Extra 16) to recuperate energy. Finally, bilateral Tsusanli (st 36), Yinlingch'uan (sp 9) and San yin chiao (sp 6) were used to soothe the liver and tonify the spleen and kidney. Each acupuncture treatment session lasted 30 minutes, with mostly bilateral needle retention over 20-30 minutes for evens techniques.
Study NCT05998421 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: routine aspirin and heparin treatment
Description: The patients accepted routine aspirin and heparin treatment. Two months before pregnancy, 50 mg of aspirin (Chenxin Pharmaceutical, China) was taken orally once a day.
Study NCT05998421 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: routine aspirin and heparin treatment
Description: The patients accepted routine aspirin and heparin treatment. Two months before pregnancy, 50 mg of aspirin (Chenxin Pharmaceutical, China) was taken orally once a day.
Study NCT05033470 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dabir Mattress Overlay System
Description: Dabir Surface mattress overlay system consists of a controller and a low-profile alternating pressure (AP) surface (placed over a non-powered mattress) with hundreds of air-filled geometric nodes arranged in rows. . The multiple rows of nodes inflate and deflate in alternating sequence every five minutes. During deflation phase, the skin and soft tissues experience reduced pressure/loading and enhanced perfusion. In conjunction with Standard of Care: Debridement, Proper moisture balance, off-loading, reduce bacterial burden and nutritional counseling.
Study NCT05511272 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: blood test
Description: four blood samples will be withdrawn from the participants during the day of their frozen embryo transfer cycle
Study NCT05466864 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Belun Sleep platform
Description: BSP(Belun Technology Company Limited) is a novel wearable system using a neural network algorithm that consists of a patented wearable device (Belun Ring), a charging cradle, and cloud-based software. The Belun Ring, an FDA-cleared pulse oximeter, acquires signals from the radialis indicis artery of the proximal index finger. The Belun Ring total sleep time can be derived from features extracted from accelerometer, SpO2, and PPG signals, whereas Belun Ring AHI can be derived from Ring-TST and features extracted from HRV and SpO2 changes. The BSP proprietary OSA detection algorithm was using neural network. BSP performance can be improved by training the algorithm through continual data collection. To our knowledge, BSP is the only validated sleep platform using a medical-grade wearable pulse oximeter, actigraphy, and artificial intelligence algorithm that has the capability to identify sleep stages, detect OSA events, and monitor autonomic nervous system activity changes during sleep.
Study NCT04631211 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Thrombosomes
Description: Human platelet derived lyophilized hemostatic
Study NCT04861298 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard of care for COVID-19 as per the hospital guidelines
Description: Hospital standard of care treatment for COVID-19
Study NCT04861298 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard of care for COVID-19 as per the hospital guidelines
Description: Hospital standard of care treatment for COVID-19
Study NCT04861298 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Quercetin Phytosome (QP)
Description: Daily dose of 600 mg of Quercetin for 1st week and then 400 mg for the 2nd week
Study NCT06112145 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rehabilitation program
Description: All fingers of the injured hand are fitted with a dorsal blocking orthosis. Early passive mobilization exercises in the form of passive flexion and extension and edema massage will be taught and it will be recommended to be applied every two hours during the day.
Study NCT04631211 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Liquid Stored Platelets (LSP)
Description: Leukocyte reduced apheresis platelets or whole blood derived pooled platelet concentrate equivalent (4-6 units)
Study NCT05590078 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual reality session
Description: The 20-minute virtual reality session, in the outpatient department before surgery, immerses the patient in calm environments combined with music therapy and breathing exercises to relax and reduce anxiety.
Study NCT05590078 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: State Trait Anxiety Inventory
Description: The State Trait Anxiety Inventory (State anxiety) is a questionnaire given to adults that shows how strong a person's feelings of anxiety are right now, just now. The score is measured on arrival in the outpatient department and just before going into the intervention room (= after the virtual reality session for the experimental group)
Study NCT05590078 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: State Trait Anxiety Inventory
Description: The State Trait Anxiety Inventory (State anxiety) is a questionnaire given to adults that shows how strong a person's feelings of anxiety are right now, just now. The score is measured on arrival in the outpatient department and just before going into the intervention room (= after the virtual reality session for the experimental group)