AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06048523 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Patient cohort
Description: * For patients: annual follow-up in Neurogenetic reference center, as part of routine care, with exhaustive standardised clinical evaluation~* Paraclinical monitoring (e.g. MRI, EEG, EMG, etc.) modelled on standard care according to current recommendations~* Biological samples offered to patients in the context of research:~  * Annual blood sample~ * Annual urine sample~ * Collection of 1 skin biopsy at the inclusion visit (for 30 patients)~ * Cerebrospinal fluid sample at the inclusion visit (for 15 patients
Study NCT06048523 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Control cohort
Description: * controls without LP: 1 visit for blood, urine and optional skin biopsy~* controls with LP: additional blood and cerebrospinal fluid tubes for blood sampling and LP as part of routine care, without longitudinal follow-up
Study NCT04829344 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AG-920
Description: AG-920 Sterile Topical Ophthalmic Solution
Study NCT04829344 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo Topical Ophthalmic Solution
Study NCT06173219 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Radiotherapy combined with immunotherapy
Description: (1) SBRT 8Gy×3f, (2) LDRT 2Gy ×3f, PD-1/L1 inhibitor, periodically, until the disease progresses or intolerable toxic side effects, (4) GM-CSF, 200ug/QD, subcutaneous injection, the first course of treatment for 7 days.
Study NCT05105139 — intervention group
Intervention type: OTHER
Intervention: Allantoin/ Coal Tar/ Clioquinol
Description: Pharmaceutical Form: Shampoo Dosage: Allantoin 0.2 g/ Coal Tar 5.0 g/ Clioquinol 3.0 g Administration way: For scalp use
Study NCT05105139 — intervention group
Intervention type: OTHER
Intervention: Allantoin/ Coal Tar/ Clioquinol/ Triclosan
Description: Pharmaceutical Form: Shampoo Dosage: Allantoin 0.2 g/ Coal Tar 3.0 g/ Clioquinol 3.0 g/ Triclosan 0.3 g. Administration way: For scalp us
Study NCT05079893 — intervention group
Intervention type: OTHER
Intervention: Case control study
Description: Observational case control study
Study NCT04590469 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: COVID WHELD
Description: COVID WHELD is a COVID-19 adapted version of an established nursing home training intervention that confers benefits in well-being and neuropsychiatric symptoms for people with dementia. The adaptations include the development of digital resources to support the programme and virtual coaching.
Study NCT04857385 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radial artery hemostasis
Description: Each of the devices will be assessed for radial artery hemostasis.
Study NCT04857385 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radial artery hemostasis
Description: Each of the devices will be assessed for radial artery hemostasis.
Study NCT05760378 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Famitinib
Description: TKI
Study NCT05760378 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: PD1 inhibitor
Study NCT05760378 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Camrelizumab
Description: PD1 inhibitor
Study NCT05760378 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nab-Palitaxel/Capecitabine/Eribulin Mesylate/Carboplatin
Description: TPC
Study NCT05760378 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nab-Palitaxel/Capecitabine/Eribulin Mesylate/Carboplatin
Description: TPC
Study NCT05330845 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: IL6 assessment
Description: Blood IL6 will be assessed during trial
Study NCT05330845 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: CRP and PCT assessment
Description: Blood CRP and PCT will be assessed during trial
Study NCT06077695 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapeutic education
Description: The themes covered concern head trauma in the chronic phase.
Study NCT04665479 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Web-based legacy-making intervention through digital storytelling
Description: A child-parent dyad will participate in a nurse-delivered intervention that will guide children to create electronic digital storyboards about themselves during 6 sessions over 6 weeks.
Study NCT04964622 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: nurofen
Description: tablet
Study NCT04964622 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: nurofen
Description: tablet
Study NCT05644912 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transanal irrigation (TAI)
Description: Transanal irrigation (TAI) with new catheter on subjects experienced in using TAI with balloon catheter.
Study NCT06282796 — intervention group
Intervention type: DEVICE
Intervention: Echocardiography
Description: Two-dimensional, color Doppler, spectral Doppler, tissue Doppler and three-dimensional echocardiographic image recordings will be taken using a Philips Epiq 7C echocardiography device and X5-1 probe. Conventional parameters, additional parameters, and strain analyzes will be performed by TomTec AutoStrain Suite Software
Study NCT01360957 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Black cumin water extract as a traditional medicine
Description: to be given orally in a dosage of 30 ml trice daily for 60 days
Study NCT01360957 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Black cumin water extract as a traditional medicine
Description: to be given orally in a dosage of 30 ml trice daily for 60 days
Study NCT06530914 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MRG003 combined with Pucotenlimab
Description: Both interventions all drugs intravenous infusion, D1, once every 3 weeks, a total of 3 cycles.
Study NCT06530914 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MRG003 combined with Pucotenlimab+Cisplatin
Description: All interventions all drugs intravenous infusion, once every 3 weeks, a total of 3 cycles.
Study NCT06534476 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: Patients who agreed to participate in the study and met the inclusion criteria were interviewed face to face before the HD session and their verbal and written permissions were obtained by reading the voluntary consent form. The researcher interviewed the patients one-on-one and provided information about the purpose of the study and the training program. Then, scale forms were applied to the patients. In order not to interrupt the training and not to distract the patients in this group, a separate room in the Dialysis Unit was used during the training. The education booklet Living with Hemodialysis on hemodialysis management prepared in line with the literature was given to the patients by the researcher. The training of a patient lasted an average of 40-50 minutes. During and at the end of the training, the patients' questions were answered in the training room.
Study NCT06270823 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Knee-to-chest-flexion manoeuvre
Description: The obstetrician will place one hand at the neck and shoulder of the baby and gently bend the infant into dorsiflexion while with the other hand bending the hips and knees against the abdomen and chest (squatting into fetal position). This holding position will be continued for 30 seconds, while compression of the umbilical cord is avoided to maintain an undisturbed umbilical circulation to and from the infant during KCF.
Study NCT04863066 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CAR-T cells
Description: The presence of latent infected cells remains a key barrier to HIV-1 functional cure. Current approach to reducing the latent HIV reservoir is to reactivate virus-containing cells to make them be detected and eliminated by host defense. Endogenous cytotoxic T-lymphocytes (CTL) may not be adequate because of cellular exhaustion and immune escape of virus. We have designed a kind of CAR-T cell based on CTL engineered to express a scFv of a broadly neutralizing anti-HIV antibody. According to our preclinical studies, CAR-T cells strongly eradicated HIV-1-infected target cells making them a particularly suitable candidate to reach a functional HIV cure. In this clinical trial, we mainly intend to evaluate the safety of CAR-T-Cell therapy on HIV patients whose plasma HIV has been successfully suppressed after antiviral therapy.
Study NCT06101693 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Plasma biomarker levels
Description: This study will investigate the diagnostic utility and performance of:~1. Alternative cut-offs for NT-proBNP to identify HF(pEF) in people with suspected HF and obesity, in whom~2. Novel candidate biomarkers to identify HF(pEF) in people with suspected HF and obesity.~3. Novel candidate biomarkers to identify HF(pEF) in people with suspected HF and NT-proBNP \<125 ng/L~4. The prevalence of HF in people with suspected HF and low NT-proBNP \<125 ng/L).~The diagnosis of heart failure will be determined according to international guidelines, when there are symptoms and/or signs of HF in association with objective evidence of cardiac structural and/or functional abnormalities consistent with the presence of LV diastolic dysfunction/raised LV filling pressures. Non-invasive testing with rest and diastolic stress echocardiography will be used to evaluate for evidence of raised filling pressures, in order to make the study procedures applicable to usual clinical practice.
Study NCT06507267 — intervention group
Intervention type: OTHER
Intervention: Pain and Clinical Reflections in Pelvic Congestion Syndrome
Description: Pain and Clinical Reflections in Pelvic Congestion Syndrome
Study NCT05328531 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Genakumab for Injection
Description: 150 mg/1ml/bottle
Study NCT05328531 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo for Genakumab for Injection
Description: The placebo contains other excipients except Genakumab, and its appearance is consistent with that of Genakumab for injection
Study NCT04955639 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Standard of Care - Control Smoking Cessation Program
Study NCT04955639 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pivot
Description: Pivot Program Smoking Cessation Program
Study NCT06215274 — intervention group
Intervention type: OTHER
Intervention: Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.
Description: The cognitive leisure activity levels, cognitive function, and MRI characteristics in people in the preclinical stage of Alzheimer's Disease (AD).
Study NCT06077695 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: tDCS
Description: The constant electric current will be delivered at an intensity of 2 mA for 20 minutes.The anode will be placed opposite the dorsolateral prefrontal area on the right. The cathode (or reference electrode) will be positioned opposite the supraorbital area on the left. This methodology is based on the general directions and results from scientific studies which aimed to improve the efficiency of neural networks engaged in attentional processes and working memory.
Study NCT06077695 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cognitive remediation
Description: Personalized sessions combining 2 approaches:•Retraining deficit components of working memory.exercise the strengthening of metacognition and the learning of reorganization-facilitation strategies. At the end of each exercise, the participant will be asked to analyze their performance and will benefit from feedback from the rehabilitator as well as a discussion on the use of the strategies. Finally, all of the proposed tasks will be made up of several levels of complexity; moving to a more complex stage will require more than 90% success in the exercise.•More ecological exercises will also be carried out in order to get as close as possible to the difficulties encountered by the patient on a daily basis. The examiner will guide the rehabilitation and propose tasks imitating his daily life.
Study NCT06098443 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupressure
Description: Acupressure is effective on anxiety and depression management. acupressure therapy at K1, ST36, and SP6 acupoints significantly reduced anxiety \& depression in patients with ESRD.
Study NCT06098443 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical nerve stimulation
Description: TENS lead to meaningful reduction of pain in patients suffering from difficult to treat phantom limb pain. This treatment has a high success rate and is associated with high satisfaction rates and no reported adverse events. The suggested duration of treatment is at least 30 minutes and may be extended up to 45 minutes. TENS delivers pulsed electric currents across the intact surface of the skin to stimulate peripheral nerves and the spinal cord, resulting in segmental and extra segmental analgesia. TENS delivers pulsed electric currents across the intact surface of the skin to stimulate peripheral nerves and the spinal cord, resulting in segmental and extrasegmental analgesia. (Vathakul et al., 2022).
Study NCT05160402 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IGM-6268
Description: Active comparator
Study NCT05160402 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo comparator
Study NCT05020886 — intervention group
Intervention type: BEHAVIORAL
Intervention: turning task
Description: Several trials included bilateral turning in 30, 60, 90, 120, 150, 180 degree.
Study NCT04749420 — intervention group
Intervention type: OTHER
Intervention: Survey study
Description: Cervical Radiculopathy Impact Scale (CRIS) will be applied
Study NCT04691765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Kineret
Description: escalating doses of drug will be administered to 3 groups of 4 patients for 7 months
Study NCT05489679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AC682
Description: Participants will receive AC682 by mouth daily in 28-day cycles.
Study NCT05455749 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: holoBLG
Description: holo-BLG (beta-lactoglobulin) - a major component of the protein fraction of raw milk, loaded with ligands (vitamin A, zinc and polyphenol-iron complexes)
Study NCT06086730 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: blow bottle positive expiratory pressure
Description: Water was poured into a 1 L plastic container until it reached a 10 cm height. A 30 cm long tube was put into the water in the bottle, 8 cm deep. The participants were instructed to close their mouths around the tubing in the apparatus for three seconds to produce bubbles, do this for a total of 10 breaths, perform two huffs, then cough. Such exhalations were conducted in two sets of ten, with a five-minute pause in between. For each subject, a fresh, disposable tube and bottle were utilized,Because it is a homemade device and can be used with less equipment and with more ease at home . patient perform session three day per week for the duration of 8 weeks , each session last for 35-40 minutes.
Study NCT06086730 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: acapella
Description: Make sure the frequency adjustment dial has been rotated counterclockwise to the lowest frequency-resistance setting before using the Acapella for the first time.On a chair, adopt a straight stance. maintaining a straight back and relaxing your elbows on a table. Now gradually tilt your head upward to maintain the opening of your upper airways.Inhale more deeply than you frequently do. Make sure your lips are encircling the mouthpiece, then blow into the device with a strong expiration.You should ideally blow out roughly twice as quickly as usual.For around ten breaths, keep going like this.Make careful to expel to clear the secretions from the airways after the final try. You can even conduct 2 to 3 huffs to improve secretion elimination when necessary.It should be noted that while using the device, you must be capable of exhale for a minimum of three to four seconds. patient perform session three day per week for the duration of 8 weeks , each session last for 35-40 minutes
Study NCT04230408 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Intensified chemo-immuno-radiotherapy with durvalumab in combination with carboplatin, paclitaxel and radiation
Study NCT05250596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: Colchicine 1 mg (0.5 mg for patients ≤ 70 Kg) on-admission followed by 0.5 mg/day until discharge.
Study NCT05250596 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin
Description: Atorvastatin 80 mg on admission followed by 80 mg/day until discharge.
Study NCT05250596 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Atorvastatin 80 mg on admission followed by 80 mg/day until discharge.
Study NCT03941587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aflibercept + reduced fluence photodynamic therapy (RF-PDT)
Description: Aflibercept dosage of 2mg in 0.05ml along with intravenous infusion of Verteporfin (6mg/m2)followed by laser light at a dosage of 25Joule/cm2
Study NCT03941587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aflibercept + sham reduced fluence photodynamic therapy (RF-PDT)
Description: Aflibercept dosage of 2mg in 0.05ml along with sham photodynamic therapy
Study NCT05470478 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mobile neural decoding platform (mobile iBCI)
Description: An embedded neural signal processor device will be evaluated for its ability to provide accurate and reliable closed-loop control in a home-based brain-computer interface.
Study NCT06373757 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nano-HAP/Chitosan hydrogel
Description: The periodontal pockets more than or equal 3-5mm were isolated. Chitosan and nano-HAP hydrogel were prepared in the same steps that were mentioned in the methodology and then the prepared gel was applied to the test site of patients with the deepest probing pocket measurement once per week for 3 weeks. Periodontal dressing (Coe-pack) was to secure the hydrogel in place.
Study NCT06053567 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Aerobic Exercise
Description: Participants will select a YMCA branch and will be assigned a personal fitness instructor who will oversee a 15-week exercise intervention. The weekly exercise prescription is 75 minutes of aerobic training.
Study NCT06053567 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic Exercise
Description: Participants will select a YMCA branch and will be assigned a personal fitness instructor who will oversee a 15-week exercise intervention. The weekly exercise prescription is 75 minutes of aerobic training.
Study NCT06053567 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Counseling
Description: Participants will receive the standard tobacco cessation package of up to 5 proactive interactions from the Texas Tobacco Quitline (TTQ). Interactions are typically phone calls, but can be chat or live text if the participant prefers. Interaction 1 is for assessment and quit date planning, Interaction 2 occurs prior to the quit date and can be a group session, Interaction 3 occurs shortly following the quit date, and Interactions 4 and 5 are for relapse prevention if the smoker has quit or problem solving if they have not quit. TTQ also offers a tobacco cessation text messaging program and access to a web portal with a variety of cessation resources.
Study NCT06053567 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Counseling
Description: Participants will receive the standard tobacco cessation package of up to 5 proactive interactions from the Texas Tobacco Quitline (TTQ). Interactions are typically phone calls, but can be chat or live text if the participant prefers. Interaction 1 is for assessment and quit date planning, Interaction 2 occurs prior to the quit date and can be a group session, Interaction 3 occurs shortly following the quit date, and Interactions 4 and 5 are for relapse prevention if the smoker has quit or problem solving if they have not quit. TTQ also offers a tobacco cessation text messaging program and access to a web portal with a variety of cessation resources.
Study NCT06053567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine patch
Description: On the target quit day (week 6), participants will be provided 8 weeks of nicotine replacement therapy (24-hour transdermal nicotine patches \[TNP\]).
Study NCT06053567 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nicotine patch
Description: On the target quit day (week 6), participants will be provided 8 weeks of nicotine replacement therapy (24-hour transdermal nicotine patches \[TNP\]).
Study NCT06276855 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sleep hygiene education
Description: The sleep hygiene education booklet was prepared by the researchers by in line with the literature. The booklet contains information on the definition and benefits of sleep, sleep problems during insomnia, arrangements for regular sleep, and the principles of sleep hygiene. The principles of sleep hygiene include individual habits that facilitate sleep, proper arrangement of the physical environment, exercises before going to bed, and dietary habits. This educational content was applied to those in the experimental group. The education took an average of 30 minutes.
Study NCT06139874 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: THRIVE
Description: Early intervention for depression that directly targets developing affective systems and builds on the empirical literature on emotion development and prevention.
Study NCT06139874 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Parenting Wisely
Description: Online asynchronous parenting program.