AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06571292 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intensive training with robotic exoskeleton for upper limbs
Description: Both groups will be trained with robotic exoskeleton for upper limbs and task specific training.
Study NCT06571292 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Task specific training
Description: Both groups will be trained with robotic exoskeleton for upper limbs and task specific training.
Study NCT06571292 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Task specific training
Description: Both groups will be trained with robotic exoskeleton for upper limbs and task specific training.
Study NCT06702189 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: EXOPULSE MOLLII SUIT (sham)
Description: It consists of applying the same parameters used for the active session (low frequency: 20 Hz; current intensity: 2 mA; pulse width ranging from 25 to 175 µs) but for a shorter duration of time (1 minute).
Study NCT06700603 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Irinotecan liposome (Nal-IRI) in combination with 5-FU/sodium levofolinate
Description: Irinotecan liposome (Nal-IRI) in combination with 5-FU/sodium levofolinate，Every 2 weeks until disease progression or patient develops intolerable toxicity
Study NCT05872958 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD3152
Description: AZD3152 will be administered via IM injection or IV infusion, as per the assigned arms.
Study NCT06702358 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Potential Therapeutic Implications of laser Acupoints on Visceral Fat and Hormonal Changes in Post-menopausal Women
Description: Application of laser acupuncture ( E M E ) on 10 acupuncture procedure for each woman which will be detected by therapist according to Acupuncture points Will stimulate St 25 (Tianshu), St 36 (Zusanli), Liv 3 (Taichong); P 6 (Neiguan), H 7 (Shenmen) for the psychical aspect of the therapy and Auriculothera- py: 55 (Shenmen) and 87 (Stomach) Each point stimulating will be Stimulation time, 30 s/point
Study NCT06702267 — intervention group
Intervention type: DEVICE
Intervention: arterial blood samplers with needles PICO70 and safePICO syringes.
Description: PICO70 is a self-filling syringe for sample volumes in the range of 0.3-1.5 mL. All syringes are delivered with needle cube for safe needle disposal and a standard tip cap to reduce the risk of blood contact during blood mixing and sample transportation.~safePICO is a more advanced group of syringes based on the PICO70 family. They contain a gold coated magnetic steel ball facilitating automatic mixing of the blood when being used with the Radiometer ABL 90 with mixing module. The safePICO is a self-filling syringe covering a volume range of 0.7-1.5 mL and includes a vented safe tip cap (VTC), which simplifies removal of air bubbles and avoid the operator to get in contact with the blood, after attachment to the syringe. Some variants of safePICO are delivered with a needle shield device (NSD) to ensure safe removal of the needle.
Study NCT06703827 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The metacognitive training group
Description: The MCT will consist of spending 90 minutes a week in a small online group setting working through a series of workshops. Participants will also be asked to complete homework each week and they will be supported with this. Interviews and questionnaires regarding symptoms and thinking errors will be used before and immediately after the intervention. The participants who attended the group and improved in their symptoms and thinking errors will be invited to an interview asking them what worked for them and how they found the group.
Study NCT06702527 — intervention group
Intervention type: PROCEDURE
Intervention: Mitral transcatheter edge-to-edge repair
Description: Mitral transcatheter edge-to-edge repair with the PASCAL system
Study NCT06702943 — intervention group
Intervention type: DRUG
Intervention: Tigecycline (Tygacil)
Description: tigecycline-based regimen administered both intravenously (IV) and intraventricularly (IVT) for 14-21 days
Study NCT06702943 — intervention group
Intervention type: DRUG
Intervention: Colistimethate sodium (CMS)
Description: Colistimethate sodium-based regimen (standard therapy for MDR infections) administered both IV and IVT for 14-21 days.
Study NCT06702982 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: tele-nursing educational program
Description: The intervention administered in this study was a tele-nursing educational program aimed at improving cancer patients' management of chemotherapy-related symptoms and enhancing their quality of life. The program was delivered via a Telegram group, which provided a platform for regular interaction between the patients and nursing staff. The educational content was designed to address common chemotherapy-related symptoms, such as nausea, fatigue, pain, and loss of appetite, and to provide guidance on managing these symptoms effectively.
Study NCT05872958 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is a matching volume of 0.9% sodium chloride, will be administered via IM injection or IV infusion, as per the assigned arms.
Study NCT06455098 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: OMNYPULSE™ Catheter with the TRUPULSE Generator
Description: OMNYPULSE™ Catheter and TRUPULSE™ Generator will be used for PF ablation.
Study NCT05266209 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Coconut oil skin care group
Description: No special technique was used for sample selection, random sample selection will be made. In the evaluation made according to the large effect size, the number of samples determined for Power: 0.80, :0.20 and :0.05 was determined as 66, with a minimum of 22 for each group. Calculations were made in computer environment using Power analysis (G\*Power 3.1.9.2) program. Random selection method will be used while creating research groups. Coconut oil, sunflower oil and control groups will be formed according to the order of admission to the unit. E.g; Coconut oil is planned for the first hospitalized newborn, sunflower oil for the second newborn, and third hospitalized newborn control group. This order will be repeated until a sufficient number of cases is reached when the newborns are included in the groups.
Study NCT05266209 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Coconut oil skin care group
Description: No special technique was used for sample selection, random sample selection will be made. In the evaluation made according to the large effect size, the number of samples determined for Power: 0.80, :0.20 and :0.05 was determined as 66, with a minimum of 22 for each group. Calculations were made in computer environment using Power analysis (G\*Power 3.1.9.2) program. Random selection method will be used while creating research groups. Coconut oil, sunflower oil and control groups will be formed according to the order of admission to the unit. E.g; Coconut oil is planned for the first hospitalized newborn, sunflower oil for the second newborn, and third hospitalized newborn control group. This order will be repeated until a sufficient number of cases is reached when the newborns are included in the groups.
Study NCT06702670 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment with Diphenhydramine
Description: Diphenhydramine 50mg IV will be administered within 1 hour of the cervical exam which diagnosed prolonged active phase of labor
Study NCT06702670 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Usual Care
Description: Participants will receive cervical exams every 2 hours in active labor, placement of intrauterine pressure catheter, up titration of Pitocin if contractions are inadequate, maternal repositioning, and use of adjunct devices such as a peanut ball.
Study NCT06702670 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Usual Care
Description: Participants will receive cervical exams every 2 hours in active labor, placement of intrauterine pressure catheter, up titration of Pitocin if contractions are inadequate, maternal repositioning, and use of adjunct devices such as a peanut ball.
Study NCT06703554 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sage Oil Mouthwash
Description: Sage oil obtained from a local market of herbal products in Egypt. In order to identify chemical composition of sage essential oils and overall purity, Gas Chromatography/ Mass Spectrometry analysis (GC/MS) performed
Study NCT06703554 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Chlorohexidine Mouthwash
Description: 0.12% chlorhexidine gluconate in a base containing water, 11.6% alcohol, glycerin, PEG-40 sorbitan diisostearate, flavor, and sodium saccharin
Study NCT06703008 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TEE hemodynamic monitoring
Description: Transesophageal echocardiography monitoring to guide administration of fluids, vasopressor and inotropes during liver transplantation in order to avoid hypotension.
Study NCT05042687 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tc99m sestamibi
Description: Given by IV
Study NCT06117111 — intervention group
Intervention type: DEVICE
Intervention: PaMo monitoring device
Description: Comparison of the device to standard monitoring
Study NCT04639310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XEN496
Description: XEN496 sprinkle capsules. Parents / caregivers will be instructed to sprinkle and mix the contents of the capsules into soft foods or liquids and feed it to the child TID.
Study NCT04639310 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo sprinkle capsules. Parents / caregivers will be instructed to sprinkle and mix the contents of the capsules into soft foods or liquids and feed it to the child TID.
Study NCT05183230 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WellPATH-PREVENT
Description: WellPATH-PREVENT is a novel personalized, easy to use, mainly stand-alone mobile intervention which focuses on the exclusive use of the WellPATH tablet app and includes training meetings during hospitalization, and virtual post-discharge coaching meetings. The meetings aim to: a) identify stressors and triggers of negative emotions associated with increased suicidal ideation or with suicidal behavior; b) develop techniques (text or video) to increase cognitive reappraisal ability; c) incorporate the techniques into the WellPATH app and promote the use of WellPATH during stressful incidents, triggers of negative emotions, or scheduled brief training sessions; and d) remotely update the triggers, negative emotions, and techniques in the app.
Study NCT05183230 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Optimized WellPATH-PREVENT
Description: The Optimized WellPATH-PREVENT intervention will be as described above, but based on the results of the Proof-of-Concept (R61) Phase, an expert committee will help select the duration (6 or 12 weeks) that shows greater improvement in cognitive reappraisal.
Study NCT06132412 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation
Description: Transcranial direct current stimulation (tDCS) is a form of noninvasive brain stimulation that can have neuromodulatory effects on central nervous system structures, specifically the primary motor cortex (M1), and can potentially target maladaptive plasticity and nociplastic sources of pain. There is both anodal and cathodal tDCS, anodal stimulation increases excitability of the cortex whereas cathodal stimulation decreases excitability. At the synaptic level, anodal tDCS induces effects that mimic long term potentiation (LTP), while cathodal tDCS results in long term depression.
Study NCT06132412 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: transcranial direct current stimulation
Description: Transcranial direct current stimulation (tDCS) is a form of noninvasive brain stimulation that can have neuromodulatory effects on central nervous system structures, specifically the primary motor cortex (M1), and can potentially target maladaptive plasticity and nociplastic sources of pain. There is both anodal and cathodal tDCS, anodal stimulation increases excitability of the cortex whereas cathodal stimulation decreases excitability. At the synaptic level, anodal tDCS induces effects that mimic long term potentiation (LTP), while cathodal tDCS results in long term depression.
Study NCT04908813 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: IV Q3W D1
Study NCT04908813 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: PO Q3W D1-D14
Study NCT04908813 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: PO Q3W D1-D14
Study NCT06132412 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical therapy
Description: Participants will receive individualized and impairment-based physical therapy treatment for their knee pain. This treatment can involve manual therapy, exercise or balance training depending on their particular needs.
Study NCT06132412 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: physical therapy
Description: Participants will receive individualized and impairment-based physical therapy treatment for their knee pain. This treatment can involve manual therapy, exercise or balance training depending on their particular needs.
Study NCT04932265 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: HRG80™ Red Ginseng
Description: Capsules containing red ginseng preparation HRG80 capsules, 200 mg - reference product
Study NCT04932265 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: HRG80™ Red Ginseng + gamma cyclodextrin
Description: Chewable tablets containing red ginseng preparation HRG80 (100 mg) incorporated in gamma-cyclodextrin (GCD) - experimental modified product
Study NCT04335877 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Private sector component + modified BCC
Description: Intervention group will be exposed to the private sector component + modified BCC and will receive current standard care
Study NCT01713803 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Buprenorphine and naloxone
Study NCT01713803 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Buprenorphine and naloxone
Study NCT04961333 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multidisciplinary Rehabilitation
Description: Body therapies to improve breathing, normalise dysfunction in the autonomic nervous system, relaxation, mindfulness, in some part Acceptance and Commitment Therapy given preferably through body therapies.
Study NCT04452344 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: opioid-containing analgesic
Description: hydrocodone/ acetaminophen combination product
Study NCT04452344 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: two over-the-counter analgesics
Description: combination of over-the-counter analgesics (ibuprofen/acetaminophen)
Study NCT06572904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tenoxicam Injectable Product
Description: (EPICOTIL® Tenoxicam 20 mg , Manufactured by: EGYPTIAN INTERNATIONAL PHARMACEUTICAL INDUSTRIES COMPANY, ReStore at a temperature not exceeding 30°C.)
Study NCT06572904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
Description: \* (Hyalubrix® hyaluronic acid sodium salt 30 MG/2 ML, manufactured by Fidia SPA,Italy, stored at temperature > 25 °C)
Study NCT05456035 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Description: The study has two intervention arms to which depressed adolescents will be randomized: (1) CBTSCT is cognitive behavioral therapy enhanced with training in social cognitive abilities (e.g., social perspective taking), and (2) CBT only is cognitive behavioral therapy without the additional social cognitive training component.
Study NCT05456035 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Description: The study has two intervention arms to which depressed adolescents will be randomized: (1) CBTSCT is cognitive behavioral therapy enhanced with training in social cognitive abilities (e.g., social perspective taking), and (2) CBT only is cognitive behavioral therapy without the additional social cognitive training component.
Study NCT06487039 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EB-203
Description: Subjects will receive EB-203 according to the following dosage and administration method for each treatment group.
Study NCT05715645 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Unilateral prosthetic knee surgery
Description: Unilateral prosthetic knee surgery
Study NCT05715645 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Unilateral prosthetic knee surgery
Description: Unilateral prosthetic knee surgery
Study NCT05715645 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Analgesia
Description: Analgesic management by adductor canal block
Study NCT05715645 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Analgesia
Description: Analgesic management by adductor canal block
Study NCT05797805 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tegavivint
Description: The first part is a phase 1 single-agent dose escalation, optimization, and expansion study of tegavivint in patients with advanced HCC after failure of at least one line of prior systemic therapy.~Tegavivint single agent dosing regimen: Tegavivint will be administered weekly on Days 1, 8, 15, and 22 of a 28-day cycle
Study NCT05797805 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: In the second part of the study, the combination of tegavivint plus pembrolizumab will be assessed with a limited dose escalation followed by a randomized dose optimization.~Tegavivint plus pembrolizumab combination dosing regimen: Tegavivint will be administered weekly on Days 1, 8, and 15 of a 21-day cycle; Pembrolizumab will be administered on Day 1 of a 21- day cycle
Study NCT06069154 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cryoneurolysis
Description: Active cryoneurolysis of the intercostal nerve of each fractured rib along with one cephalad and one caudad will be targeted: for each nerve the cryoneurolysis device will be triggered using 3 cycles of 2-minute nitrous oxide activation separated by 1-minute defrost periods (Epimed) or 1 cycle of 5.5 minutes \[1st 4 participants\] 3 minutes \[remaining participants; change based on new laboratory data\] of argon and 30 seconds of helium (Varian). For the active comparator, the gas will be deployed to the tip where a drop in temperature will result in cryoneurolysis.
Study NCT06069154 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Local anesthetic peripheral nerve block
Description: Due to the pragmatic design of this trial, study participation will not alter an institution's current practice. Examples of peripheral nerve blocks include paravertebral, erector spinae plane, and serratus anterior nerve blocks. The injectate through the introducer will depend on the treatment group: for participants of the control group, ropivacaine 0.5% or bupivacaine 0.375% (both with epinephrine 1:400,000) will be injected (volume determined by institutional standard-of-care). This will provide a peripheral nerve block for the control group.
Study NCT06069154 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Cryoneurolysis
Description: Sham cryoneurolysis of the intercostal nerve of each fractured rib along with one cephalad and one caudad will be targeted: for each nerve the cryoneurolysis device will be triggered using 3 cycles of 2-minute nitrous oxide activation separated by 1-minute defrost periods (Epimed) or 1 cycle of 5.5 minutes \[1st 4 participants\] 3 minutes \[remaining participants; change based on new laboratory data\] of argon and 30 seconds of helium (Varian). However, for the sham comparator, the gas will NOT be deployed to the tip, there will NOT be a drop in temperature, and NO cryoneurolysis will occur.
Study NCT06069154 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sham peripheral nerve block
Description: Due to the pragmatic design of this trial, study participation will not alter an institution's current practice. Examples of peripheral nerve blocks include paravertebral, erector spinae plane, and serratus anterior nerve blocks: for participants allocated to the cryoneurolysis group (experimental group), normal saline will be injected for the peripheral nerve block. This will result in a sham/placebo nerve block for the experimental group.
Study NCT06572254 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early Childhood Development Newborn Parenting Education Program
Description: Investigators will be adapting the model used here at the tertiary care of newborn parenting which investogators have developed based on the nurturing care framework and keys to the caregiving framework. Both models have shown reliable evidence of their effectiveness.
Study NCT05494398 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-acetylcysteine
Description: 12 week administration of N-Acetylcysteine to target restricted repetitive behavior severity.
Study NCT05494112 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Celastrol
Description: same dose of Celastrol will be given every day for a period of 90-days to all participants.
Study NCT05415644 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hrx0701 tablets、Metformin hydrochloride tablets、Retagliptin phosphate tablets
Description: High-specification group: subject preparation: HRX0701 (50 mg/1000 mg) 1 tablet (to be taken after a meal); Reference preparation: 1 tablet of retagliptin phosphate (50 mg), 2 tablets of metformin hydrochloride (Glucophage®) (500 mg), taken twice after meals.~Low Specification Group:~Preparation: HRX0701 (50 mg/850 mg) 1 tablet (taken after a meal); Reference: 1 tablet of retagliptin phosphate (50 mg), 1 tablet of metformin hydrochloride (Glucophage®) (850 mg), taken twice after meals.