AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04788563 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heat-sensitive moxibustion plus original antihypertensive treatment (preference selection arm)
Description: In this group, patients will self-administer heat-sensitive moxibustion or have family members help with the administration for six months. During this period, they will maintain their original antihypertensive treatment.
Study NCT04788563 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Original antihypertensive treatment (preference selection arm)
Description: In this group, patients will maintain their original antihypertensive treatment.
Study NCT06558786 — intervention group
Intervention type: OTHER
Intervention: EORTC QLQ-C30 questionnaire
Description: The EORTC QLQ-C30 has 30 items arranged into 9 scales and 6 single items. The scales are divided into 5 function scales (physical, role, cognitive, emotional, and social function), 3 symptom scales (fatigue, pain, and nausea or vomiting), and 1 global health status/quality-of-life scale. The 6 single items address specific symptoms (dyspnea, appetite loss, insomnia, constipation, and diarrhea) and the financial impact of the disease. Each item has 4 response alternatives: (1) not at all, (2) a little, (3) quite a bit, and (4) very much, except for the global health status/quality-of-life scale, which has response options ranging from (1) very poor to (7) excellent. For analysis, all questionnaire responses will be transformed into scores on a linear scale of 0 to 100 in accordance with the EORTC scoring manual. Mean scores with standard deviations will be calculated, with a higher score indicating a better health-related quality of life.
Study NCT06558786 — intervention group
Intervention type: OTHER
Intervention: QLQ-OGS25 questionnaire
Description: The QLQ-OGS25 is specific for esophageal, GEJ, or gastric cancer and consists of a symptom scale only. The QLQ-OGS25 has 6 scales: dysphagia, eating restrictions, reflux, odynophagia, pain, and anxiety. Scales have good reliability (α range, 0.67-0.87), and they distinguish between tumor sites and disease stage. The response format is a 4-point Likert scale. Responses to the questionnaires will be transformed into a scale of 0 to 100 using the EORTC guidelines, with a higher score indicating a deterioration of symptoms.
Study NCT06308484 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous vagus nerve stimulation
Description: Patients that are enrolled in a MBRP program will be subjected to weekly tVNS stimulation during a 30-minute audio guided mindfulness exercise.
Study NCT06308484 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous vagus nerve stimulation
Description: Patients that are enrolled in a MBRP program will be subjected to weekly tVNS stimulation during a 30-minute audio guided mindfulness exercise.
Study NCT06308484 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Closed-loop AM-tACS
Description: Patients that are enrolled in a MBRP program will be subjected to weekly CLAM-tACS stimulation during a 30-minute audio guided mindfulness exercise.
Study NCT06308484 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Closed-loop AM-tACS
Description: Patients that are enrolled in a MBRP program will be subjected to weekly CLAM-tACS stimulation during a 30-minute audio guided mindfulness exercise.
Study NCT06561672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tramadol plus paracetamol
Description: Intravenous infusion of 15mg/kg paracetamol together with 1mg/kg tramadol will be started and to be finished before starting of induction of anesthesia (induction agent will be propofol 2mg/kg and muscle relaxant (cisatracurium) 0.15 mg/kg)
Study NCT06561672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl
Description: Intravenous injection of 1.5 microgram/kg fentanyl will be given to the patient followed by induction agents (propofol 2mg/kg).
Study NCT06561672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: propofol and muscle relaxant (cisatracurium)
Description: propofol 2mg/kg and muscle relaxant (cisatracurium) 0.15 mg/kg)
Study NCT06561672 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: propofol 2mg/kg
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liposomal Amphotericin B (LAmB)
Description: Antifungal dosed at 10 mg/kg/day IV x one single dose.
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flucytosine (5FC)
Description: Antifungal dosed at 25mg/kg oral 3x daily.
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Flucytosine (5FC) placebo pill
Description: Similar in appearance to flucytosine. Also dosed at 25mg/kg oral 3x daily.
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flucytosine (5FC) placebo pill
Description: Similar in appearance to flucytosine. Also dosed at 25mg/kg oral 3x daily.
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Deoxycholate Amphotericin B (DAmB)
Description: Antifungal dosed at 0.7 mg/kg/day IV x 2 weeks.
Study NCT06525389 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Deoxycholate Amphotericin B (DAmB)
Description: Antifungal dosed at 0.7 mg/kg/day IV x 2 weeks.
Study NCT06562257 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Honey
Description: Honey has a long-standing reputation for promoting wound healing and offers a more economical treatment modality. Nusantara Honey, a GMP-certified product available on the market, met our criteria for quality and safety.
Study NCT06562257 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: PHMB Solution
Description: PHMB is an antimicrobial polymer that is effective against intracellular and biofilm forms of S. aureus. PHMB is quite effective in the treatment of wounds in deep neck abscesses.
Study NCT06562257 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PHMB Solution
Description: PHMB is an antimicrobial polymer that is effective against intracellular and biofilm forms of S. aureus. PHMB is quite effective in the treatment of wounds in deep neck abscesses.
Study NCT06562309 — intervention group
Intervention type: OTHER
Intervention: take feces and blood samples from patients
Description: this study does not involve any intervention
Study NCT05685498 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Peer-led HIV self-testing among male fisherfolk in Uganda
Description: This behavioral intervention is centered on the distribution of HIV self-test kits to men through their respective peer-leaders. The investigators have identified up to 18 social network groups; each group is represented by 1-2 peer-leaders who were selected during community engagement meetings. Peer-leaders have received a 3-day training in the HIV self-testing processes, communication skills, existing referral mechanisms, and basic counseling skills. After the training, each peer-leader nominated up to 20 male members (15+ years) from within their social networks who were screened for study eligibility. Eligible male social network members were administered a baseline interview and requested to go to their peer-leaders to obtain their HIV self-test kits.
Study NCT06424457 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: video assisted thoracoscopy (VATS)
Description: the investigators compare the outcomes of intervention by VATS and doing complete decortication or open surgery thoracotomy
Study NCT06424457 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: open thoracotomy
Description: the investigators assess the outcomes of intervention by doing complete decortication through open surgery thoracotomy
Study NCT05804500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cardiac Telerehabilitation (CTR) via the RecoveryPlus platform
Description: RecoveryPlus has developed an innovative CTR platform for patients with CVD that leverages: (1) video conferencing functionality (Zoom) for synchronous telehealth sessions of CR instruction for patients and licensed exercise physiologists (EPs), (2) a patient-facing mobile application delivering asynchronous exercise videos, and (3) a health care provider web portal for clinicians and EPs. The RecoveryPlus platform includes the ability for EPs and clinicians to monitor patient clinical data (e.g., heart rate) and input (e.g., rating of difficulty for individual exercises) and tailor individual patient regimens regularly for increased safety and optimal outcomes.
Study NCT05433090 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Inpatient serious illness care program
Description: Inpatient advance care planning intervention that will be delivered by advanced care practitioners or hematology/oncology fellow physicians. The intervention will be an adapted version of the serious illness care program.
Study NCT05211375 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Duodenojejunal bypass
Description: Sleeve gastrectomy will be performed in the same manner as in the SG group. DJB will be performed by transection of the duodenum and bypassing 250 cm of the proximal jejunum. The handsewn suture will be used for duodenojejunal anastomosis, and the size of anastomosis will be 1.5 - 2 cm. Single anastomosis will be performed rather than Roux-en-Y fashion.
Study NCT05211375 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve gastrectomy
Description: Sleeve gastrectomy will be performed using 36-38 Fr bougie. The initial stapling start point will be between 4-6 cm from the pylorus, and the last stapling will be performed at least 1 cm away from His angle. The height of the automatic stapler will be selected based on the researcher's discretion.
Study NCT05028010 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Capacity building
Description: Four days of training on the promotion of maternal and child nutrition will be given. The training will be based on Pender's health promotion model. Supportive supervision will be conducted.
Study NCT04667468 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cold Stored Platelets (CSP)
Description: early infusion of urgent release CSP
Study NCT04667468 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: standard care including blood and blood component therapy
Study NCT05606874 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional resin fissure sealant
Description: The occlusal fissures will be etched with a 37% phosphoric acid gel for 30 s. After rinsing the enamel with water for 30 s the enamel will be dried for 15 s with compressed air. After completing the fissure preparations a single coat of adhesive (3M ESPE ADPER ,USA) will be applied to the etched surface ,dried under gentle air flow for 2- 3 s and light cured for 20 s using a LED light curing unit with a 1000 mw output .Conventional resin fissure sealant (total etch), (UltraSeal XT®, Ultradent, USA) will be applied to the etched pits and fissures. After removing the rubber dam the occlusion will be checked the sealant will be adjusted with a composite finishing bur and polished with polishing points.
Study NCT05545163 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: I-gel with standard insertion technique
Description: Standard I-gel insertion technique (grasping I-gel from integral bite block site and cuff facing towards chin and pressing down the manikin chin. I-gel introduced in patient's mouth in a direction towards hard palate. Then I-gel slided downwards and backwards along hard palate with a continuous but gentle push until a definitive resistance is felt)~Modified jaw thrust technique (grasping I-gel from integral bite block site and cuff facing towards chin and pressing down manikin chin. I-gel introduced in patient's mouth in a direction towards hard palate with gently advancing into oropharynx. Then after, I-gel left in oral cavity and both hands used to thrust jaw by lifting angle of mandible with little fingers and other fingers to stabilise jaw. And, at this point, both hand's thumbs used to apply balance force from I-gel stem head towards final placement position by looking at integral bite block mark at incisor teeth level)
Study NCT05292677 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Steroid/Anesthesia Mixture
Description: Steroid will be Triamcinolone Acetonide (40mg/mL). Anesthetic will be 0.5% bupivacaine with 1:100,000 epinephrine. These will be pre-mixed by a qualified personnel within the ENT department.
Study NCT05805774 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Distal Femur Replacement
Description: Knee surgery to remove the lower part of the femur and knee joint (where the broken bones are) and will replace them with an artificial knee joint (prosthesis).
Study NCT05805774 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical fixation
Description: Knee surgery to fix the fracture, that can use wires, nails, screws, pins or plates to health and fix the bones together.
Study NCT05292677 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 mL of Normal Saline
Study NCT04918173 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atenativ
Description: Antithrombin concentrate
Study NCT06559501 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Integrated case manager care
Description: comprises 8 sessions delivered by case managers. Case managers will provide up to 6 low-intensity sessions in the hospital or the community (if the patient is discharged before completing the required sessions), with content and duration tailored to patient preferences. Post-discharge, patients will receive 2 follow-up sessions with case managers to ensure a smooth transition into the community.
Study NCT06459752 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: visceral manipulation and noble technique
Description: First, the patient will lie face-up on a massage or exam table. Physiotherapists feel viscera, major internal organs located in the abdomen by lightly pressing through abdominal muscles. Physiotherapist manual poking, pressing, and massage actions do three things:~1. Reveals visceral adhesions.~2. Find tender spots.~3. Breaks up adhesions. Massaging and pressing stretch the collagen fibers that makeup fascia, which loosens tightly bound fibers to break up adhesions. This releases the organs and allows them to move more freely.~Minor adhesions may resolve after one session. Tough, stubborn adhesions may require several sessions plus self-manipulation between sessions
Study NCT06459752 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: noble technique
Description: The patient is positioned in supine with both knees bent and feet flat on a firm surface. The patient then places her crossed hands over her abdomen to support and pull the rectus abdominis muscles towards the midline. Finally, the patient is asked to slowly raise her head until a slight contraction is felt in the abdomen, holding for 20 seconds and repeating the exercise up to 20 times a day
Study NCT06511661 — intervention group
Intervention type: PROCEDURE
Intervention: Complete lymphadenectomy
Description: At least 3 N1 stations and 3 N2 stations are examined during surgery, including station 7.
Study NCT06511661 — intervention group
Intervention type: PROCEDURE
Intervention: Incomplete lymphadenectomy
Description: Less than 3 N1 stations or 3 N2 stations are examined during surgery, or those without station 7 lymph node dissection.
Study NCT05088317 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Exercise capacity
Description: The incremental shuttle walking test at increasing speed (ISWT) is one of the field tests used to evaluate exercise capacity. It has been shown that ISWT is a valid and reliable assessment tool that can be used to evaluate exercise capacity in obese individuals. This test is an exercise test in which walking between two cones 10 m apart at increasing speed for 12 minutes is counted as one sit-up for each 10-meter walk between the two cones. It is continued until the patient is unable to continue the test due to shortness of breath, the heart rate reaches 85% of the maximum expected heart rate, or completes the 12-minute test. In this test, the primary measure is the distance walked, and the result is calculated based on the number of shuttles completed.
Study NCT06118879 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training
Study NCT06118879 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training
Study NCT06118879 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous electrical stimulation
Description: sensory level stimulation, one-leg standing and Y-balance training
Study NCT05907915 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low level laser therapy
Description: They recieved LLLT 1 session daily, 3 session per week for 3 weeks,with the following parameters( 650 nm wavelength, 150 mw power output, 0.25 cm2 radiation area, 0.6 W/cm2 power density, continuous mode, 2 j/ cm2, 90 seconds / cm2) in addition to the conventional medical treatment and traditional wound care (dressing)
Study NCT05907915 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: They received placebo laser 1 session daily, 3 session per week for 3 weeks in addition to the conventional medical treatment and traditional wound care (dressing)
Study NCT04752787 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online breastfeeding training
Description: Online breastfeeding training will be provided to pregnant women expecting twin babies.
Study NCT04752787 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: QR code supported online breastfeeding training
Description: QR code supported online breastfeeding training will be given to pregnant women who are expecting twin babies.
Study NCT04389138 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapy Intervention
Description: Physiotherapy intervention will include an assessment to identify individual areas that physiotherapy should target. Intervention will be based on the core areas recommended by the European Physiotherapy Guideline for Parkinson's Disease: physical capacity (muscle power, tone, joint range of movement, exercise tolerance and pain), transfers, manual dexterity, balance and gait. Posture is incorporated as part of these 5 core areas. The intervention will be delivered over 4 visits.
Study NCT04631718 — intervention group
Intervention type: RADIATION
Intervention: Magnetic Resonance Imaging (MRI)-based Quantitative Susceptibility Mapping (QSM)
Description: MRI-based QSM methods estimate the susceptibility of tissues based on measuring the magnetic field distortion produced by the tissues themselves.~Upon successful validation, MRI-based abdominal QSM will provide accurate, repeatable, and reproducible quantification of Liver iron concentration (LIC) that is independent of the distribution of iron and does not require calibration.
Study NCT05332262 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of platelet reactivity
Description: Assessment of platelet reactivity and HPR status will be performed post-PCI. Platelet reactivity will be measured by VerifyNow P2Y12 and HPR status will be defined using a cut-off value of platelet reactivity units (PRU)>208.
Study NCT05332262 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Troponin measurement
Description: Measurement of high sensitivity troponin for the assessment for the presence of myocardial infarction/myocardial injury will be performed post-PCI.
Study NCT05957211 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.09% cyclosporine A ophthalmic solution
Description: Cequa is an ophthalmic solution used to treat moderate to severe dry eye disease. The typical dosage is one drop in each eye, twice a day. The drug is packaged in sterile, single use bottles.
Study NCT05377840 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy
Description: CBT is a combined psycho-social intervention that aims to improve overall mental health focusing on developing coping strategies. standard CBT Participants will have individual weekly sessions lasting 60 minutes each over an 8-week period with 1 follow-up maintenance session at week 12.
Study NCT05991479 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercises
Description: Pilates exercises:~The subjects will receive Pilates training (3 sessions/week) for 8 weeks. The Pilates training protocol will take 60 min per session, including 10 min of warm up prior to initiating the Pilates technique, 40 min for Pilates exercises and 10 min for cool down. The number of repetitions will be 10 times. The patient will perform the following Pilates exercises: (Hundred exercises, spine stretch, single leg stretch , double leg stretch, criss cross, swimming, one leg kick, side kick, clam, one leg circle, shoulder bridge, hip twist, roll up and down and standing footwork).
Study NCT05991479 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional physical therapy programme:
Description: All patients will receive a traditional physical therapy programme consisting of 45 minutes per session of a supervised and individualized exercise programme for three sessions per week for eight weeks which will include:~Stretching exercises for calf and hamstring muscles. Strengthening exercises for hip, knee, ankle, and foot muscles. Deep friction massage for scar management.
Study NCT04936932 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 1064 nm long-pulse Nd:YAG laser
Description: BCC lesion will be treated with long-pulse 1064 laser
Study NCT05377840 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sudarshan Kriya Yoga
Description: SKY Breath Meditation is a deep breathing and meditation technique that enables physiological changes leading to improved mental and physical health. Participants will first attend a 3-day online workshop (2.5 hours each day) delivered live by a certified instructor to learn the SKY Breath Meditation practice. Participants will then practice SKY 25 minutes daily for 6 weeks and 3-4 times per week up to 12 weeks.
Study NCT00960817 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Statin, aspirin