AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05513924 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 5Fluorouracil
Description: The affected area cleaned with betadine surgical solution followed by alcohol 70%.~Local anesthetic, pridocaine cream, applied on the treated area under occlusion for 30 min before the procedure.~Using automated microneedling device (Dr Pen Derma Pen Ultima A6®) , which has a disposable head that personalized for each patient and sterilized after each session.~The derma pen will penetrate the skin with variable depths ranging from 0.25 to 0.5 mm (not more than the depth of the epidermis). It will pass vertically over the vitiligo area in a circular pattern until pinpoint bleeding appears.~Topical application of 5-fluorouracil 5% solution will be rubbed over the affected area for about 2 minutes. Occlusive dressing for hours.~This procedure will be repeated every two weeks for six months.
Study NCT06137014 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fortified Oral Rehydration Therapy
Description: Oral rehydration solution with reduced glucose and added amino acids.
Study NCT06137014 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Standard of Care Oral Rehydration Therapy
Description: Glucose-based oral rehydration therapy according to World Health Organization guidelines.
Study NCT05112107 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culinary workshops
Description: Approved ketogenic recipes will be applied in educational cooking workshops at the ketogenic diet clinic at Instituto da Criança HCFMUSP.
Study NCT04876677 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Beclomethasone dipropionate/Formoterol Fumarate/Glycopyrronium
Description: Two inhalations bid: 4 inhalations; total daily dose of 400/24/50 μg BDP/FF/GB
Study NCT05276609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-20093 (Phase Ia: Dose escalation)
Description: Intravenous (IV) administration of HS-20093 Q3W; Participants will continue treatment until the end of the study in the absence of unacceptable toxicities and confirmed disease progression.
Study NCT05276609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-20093 (Phase Ib: Dose expansion)
Description: IV administration of HS-20093 Q3W; Participants will continue treatment until the end of the study in the absence of unacceptable toxicities and confirmed disease progression.
Study NCT05631431 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Curalin
Description: Curalin capsules, 2 capsules, 3 times a day after meals Placebo: matching placebo capsules, 2 capsules, 3 times a day after meals
Study NCT06213857 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Silymarin
Description: Silymarin (milk thistle), an extract obtained from Silybum marianum seeds containing a complex of flavonolignans with a potent intracellular antioxidant property. The first usage of Milk thistle was for its hepatoprotective and antioxidant activities, but in the recent years it has been used to control of immune based murine colitis by healing of bowel histology and reduction of bowel inflammatory cytokines especially TNF-α, interleukin-1β (IL-1β), and nuclear factor κB (NF-κB). Silymarin has anti-viral, immunomodulation, anti-inflammatory effects as well as antioxidant properties by scavenging free radicals and increasing the glutathione concentrations, protective and wound healing effects. It increases the gene expression of antioxidant enzymes and the number of the most important protection mechanisms against free-radicals damage containing superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase.
Study NCT05743491 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Care
Description: Cancer survivors assigned to this condition continue with the standard follow-up care provided by their treating oncologists as appropriate for individual diagnoses. Participants in the control condition were offered the 4-week YOCAS©® program gratis after completing all study requirements.
Study NCT05743491 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: YOCAS©®
Description: YOCAS©® is a standardized yoga program designed specifically for use by cancer patients and survivors. The YOCAS©® program is a low to moderate intensity mode of exercise that draws from two basic types of yoga: gentle Hatha and Restorative yoga. The program includes 18 specific physical postures (asanas) and mindfulness exercises focused on breathing (pranayama) and meditation (dhyana). The program is designed to be delivered by certified yoga instructors in community settings, two times a week for 75 minutes over four weeks.
Study NCT05760040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: vırtual reality
Description: During the intrauterine device application, 40 women who were included in the virtual reality group will be put on virtual reality glasses and watched the video.
Study NCT05760040 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control Group
Description: Routine hospital protocol will be applied to 40 women included in the control group while intrauterine device application is being made.
Study NCT04557891 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active LIFUP Treatment
Description: 8 LIFUP Treatments
Study NCT04557891 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham LIFUP Treatment
Description: 8 sham LIFUP treatments
Study NCT05631431 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Curalin
Description: Curalin capsules, 2 capsules, 3 times a day after meals Placebo: matching placebo capsules, 2 capsules, 3 times a day after meals
Study NCT05220254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MindCotine's VR app
Description: The MindCotine program would be a 6-week intervention to help users utilize mindfulness based skills, and involves virtual exposure therapy.
Study NCT04875676 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: VXA-G1.1-NN
Description: Norovirus GI.1 Norwalk VP1 Vaccine, Oral E1-/E3-Deleted Replication Defective Recombinant Adenovirus 5 with double-stranded RNA Adjuvant
Study NCT05423626 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: technologies of robotic mechanotherapy with FES
Description: Technologies of robotic mechanotherapy with FES (ExoAtlet I):~Simulator is designed for rehabilitation in case of motor deficiency of the lower extremities and recovery of walking caused by stroke and other diseases and injuries of the central nervous system.~The main components of the simulator are:~* exoskeletal robotic device for moving the patient and forming a walking pattern~* a device for functional electrical stimulation (FES) of peripheral nerves controlling the muscles of the rehabilitated limb.
Study NCT05423626 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: biofeedback virtual reality technologies
Description: Brief information biofeedback virtual reality technologies:~ReviVR Multisensory Passive Rehabilitation Simulator is intended for rehabilitation in case of motor deficiency of the lower extremities and recovery of walking caused by stroke and other diseases and injuries of the central nervous system.~The main components of the simulator are:~* hardware and software complex, including a monitor and a personal computer;~* virtual reality helmet;~* sandals with air chambers.
Study NCT05344820 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Art based mandala
Description: To the experimental group; Mandala practice will be done for 2 hours, once a week for 8 weeks.
Study NCT05901662 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Competence training program
Description: A 3-hour weekly course training session in four consecutive weeks and provided services to community-dwelling older adults for two months.
Study NCT05901662 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: This group provided their routine services at senior activity centers.
Study NCT06380491 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin 3 MG Oral Tablet
Description: Participants with OSA and nocturnal non-dipping Blood Pressure will be randomly assigned to a treatment with melatonin 3mg/d or to receive only the usual care.
Study NCT05642403 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: XW001
Description: Inhaled XW001
Study NCT05642403 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matched inhaled placebo
Study NCT04894266 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apabetalone
Description: Apabetalone 100mg BID
Study NCT04894266 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care
Description: Standard of Care
Study NCT04894266 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of care
Description: Standard of Care
Study NCT05279755 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: prosetin
Description: oral solution
Study NCT05279755 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: oral solution
Study NCT04642092 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PsicAP protocol
Description: The intervention will include: psychoeducation, relaxation and breathing techniques, thought management, tips to improve quality of life and relapse prevention. All of these activities will be based on scientific evidence and many of these aspects will be supported by mobile devices.
Study NCT04642092 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: Typical treatment that is currently given to patients with emotional disorders in Dominican primary care units.
Study NCT05405803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-App based Lifestyle Physical Activity Promotion Program
Description: WPAPP-K includes group and individual coaching/support by health care providers, peer coaching/support, and information to change the women's attitudes, self-efficacy, perceived barriers, and social influences.~The program includes 3 components in 2 languages (English and Korean):~1. Social media sites: allow participants to share their experiences and to receive individual and group coaching/ support from culturally matched peers and healthcare providers.~2. Interactive online educational sessions: information on 15 topics related to depressive symptoms and lifestyle physical activity.~3. Online Resources: include 20 links in English or Korean (only from scientific authorities including NIH, CDC,etc.).~Weekly group coaching and support will start after the first 10 participants are enrolled, but individual coaching/support will start as soon as a participant enrolls.
Study NCT05405803 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: The Centers for Disease Control and Prevention (CDC) website on depression and physical activity guidelines
Description: A link to the CDC website will be provided through the project website, and participants will be asked to use it during the study period (12 months). Their use of the CDC website will be automatically measured through the project website.
Study NCT05405803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Centers for Disease Control and Prevention (CDC) website on depression and physical activity guidelines
Description: A link to the CDC website will be provided through the project website, and participants will be asked to use it during the study period (12 months). Their use of the CDC website will be automatically measured through the project website.
Study NCT05313555 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultraviolet Light (UV-B)
Description: This control group will receive a UV-B exposure as a positive control. Participants will have punch biopsies after exposure.
Study NCT05313555 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ultraviolet lights (UV-C)
Description: Violet is tabletop device that emits filtered UV-C (200nm-230nm; peak at 222nm). Participants will choose, based on availability, to be in groups that deliver 1 cycle, 10 cycles, 15 cycles or 25 cycles of the Violet. The subject will be exposed for no more than 5 minutes and 20 seconds in total. Participants will have punch biopsies after exposure.
Study NCT04805190 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Intervention
Description: This intervention comprises three components: 1) general education about pain (e.g., pain pathways) and a rationale for the intervention (e.g., gate control theory); 2) impact of positive and negative pain-related thoughts on neural process of pain; and 3) a guided imaginal pain exposure exercise.
Study NCT04805190 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Education
Description: General information about the neurobiology of pain and knee osteoarthritis will be given to participants assigned to this intervention.
Study NCT05049954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calorie-Restricted Healthy Ketogenic Diet
Description: Participants in the experimental group will be advised on a Calorie-restricted Healthy Ketogenic Diet via 7 workshops. Participants will also be advised to monitor their urinary ketones to track compliance.
Study NCT05049954 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Calorie-Restricted Low Fat Diet
Description: Participants will be advised on Calorie-restricted Low Fat diet via 7 workshops.
Study NCT06434454 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EFT Group:Emotional Free Technıcal
Description: The young individuals in the intervention group will be informed about the study, including its purpose and methodology, and their consent will be obtained. Emotional Freedom Techniques (EFT) will be applied to groups of 20 individuals to improve sleep quality, and all scales will be administered beforehand. EFT will be applied twice, with a 15-day interval between sessions, and the same scale questionnaires will be administered again after the second EFT session. Subsequently, the analysis will be conducted.
Study NCT05333770 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-frequency repetitive transcranial magnetic stimulation
Description: TMS is an investigational device that provides a way to test the function of a specific part of the brain that is devoted to moving my affected upper limbs by directing a low electrical current to that part of the brain through the scalp.
Study NCT04553250 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Doubled-stapled colorectal anastomosis
Description: Anastomosis performed between the colon an the rectal stump, using a double-stapled technique.
Study NCT05379660 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: Basing on the theory of traditional Chinese medicine, bilateral Zusanli (ST 36), Shangjuxu (ST 37) and Sanyinjiao (SP 6) are elected as the acupuncture points,the electrode pads with wire are attached to the corresponding acupoints, which are connected with Hwato electric acupuncture treatment instrument,TEAS stimulation uses a dense-dispersed wave with frequencies of 2 and 100 Hz alternating every 3 s, and the intensity 5 \~ 12mA,on the first and second days after surgery, the doctor who is responsible for acupuncture will arrive at the ward in the morning and afternoon to administer TEAS stimulation at the same acupoints for 30 min in the TEAS groups
Study NCT05057845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Tislelizumab will be initiated on day 14 after cryoablation. Tislelizumab will be administered at 200 mg i.v. every 3 weeks
Study NCT05057845 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lenvatinib
Description: Lenvatinib will be initiated on day 14 after cryoablation. Lenvatinib will be administered (bodyweight ≥ 60 kg, 12 mg; \< 60 kg, 8 mg) orally daily every 3 weeks until documented disease progression, development of unacceptable toxicity, participant request, or withdrawal of consent.
Study NCT05057845 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: US/CT-guided Percutaneous Cryoablation
Description: Cryoablation will be performed with a two-cycle freeze-thaw phase protocol; US or non-contrast CT images will be obtained to visualize the evolving ablation zone
Study NCT05973435 — intervention group
Intervention type: OTHER
Intervention: Blood sampling
Description: Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).
Study NCT04819984 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TCM5 device (Radiometer) for PtC02 continuous measurement
Description: Evaluation of PtC02 variation as a reflect of PaC02 during 30 minutes of weaning proof for mechanical ventilation (spontaneous ventilation on T-piece)
Study NCT04869423 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dog-Assisted Therapy
Description: During seven weeks patients will assist one time per week (1 hour). The therapy will be conducted by an expert psychologist. The intervention will consist of 7 weeks conducted once a week (50 minutes each session). It will include three parts: 1) a welcome part aimed to get in touch with the dog, 2) a main part, where participants will be taught basic notions about dog training and then try to train the dogs. In this part, the patients will perform different activities and exercises with the dog. 3) A closing part to say goodbye to the dogs.
Study NCT04891822 — intervention group
Intervention type: PROCEDURE
Intervention: ERAS protocol
Description: E: ERAS protocol C: control
Study NCT05085236 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Fu's subcutaneous needling (FSN)
Description: physician will use a disposable Fu's subcutaneous needling (FSN) to penetrate the subject's skin in the middle from elbow lateral epicondyle to radial styloid process. Then physician will push forward the needle parallel to the skin surface. the physician will sway the needle 100 times in a minute. After procedure of swaying needle, the physician will instruct subject to do several movements, and each movement will perform 10 seconds and rest 10 seconds for 3 repetitions. The movements are active isometric elbow flexion, active isometric shoulder internal rotation, passive shoulder external and internal rotation. After above re-perfusion approach of muscles, the physician will take out the needle to finish the treatment.
Study NCT05085236 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rehabilitation
Description: Rehabilitation mentioned here is the regular rehabilitation programs for treating post-stroke hemiplegic shoulder pain prescribed by the rehabilitation physician.
Study NCT05085236 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rehabilitation
Description: Rehabilitation mentioned here is the regular rehabilitation programs for treating post-stroke hemiplegic shoulder pain prescribed by the rehabilitation physician.
Study NCT05802680 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial photobiomodulation
Description: Administration of Sham or 1064 (+/- 50) nanometers tPBM
Study NCT06177496 — intervention group
Intervention type: PROCEDURE
Intervention: local ablation
Description: treatment of HCC
Study NCT06177496 — intervention group
Intervention type: PROCEDURE
Intervention: TACE
Description: treatment of HCC
Study NCT05802680 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial photobiomodulation
Description: Sham treatment
Study NCT05560971 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Palmitoleic acid
Description: Participants will be randomized to either POA or placebo and will be asked to take 2 capsules of the POA or placebo twice a day for 8 weeks.
Study NCT05560971 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Medium chain fatty acids in triglyceride form in capsules with the same shape, color, size and odor of POA capsules
Study NCT06177496 — intervention group
Intervention type: DRUG
Intervention: Sorafenib
Description: treatment of HCC
Study NCT06035679 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyrotinib and Trastuzumab
Description: Small and large molecules combined with chemotherapy for neoadjuvant treatment of HER2-positive breast cancer
Study NCT04753970 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cilostazol
Description: Cilostazol 100mg BID
Study NCT06262685 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preemptive pharmacogenetic atorvastatin dose based on CPIC guidelines
Description: Atorvastatin at the dosage reccomended by the 2022 Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and considerations for Statin-Associated Musculoskeletal Symptoms based on the subjects pharmacogenetic phenotype. A comprehensive description of said doses are can be accessed at: https://cpicpgx.org/guidelines/cpic-guideline-for-statins/
Study NCT06262685 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preemptive pharmacogenetic simvastatin dose based on CPIC guidelines
Description: Simvastatin at the dosage reccomended by the 2022 Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and considerations for Statin-Associated Musculoskeletal Symptoms based on the subjects pharmacogenetic phenotype. A comprehensive description of said doses are can be accessed at: https://cpicpgx.org/guidelines/cpic-guideline-for-statins/
Study NCT06262685 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preemptive pharmacogenetic pitavastatin dose based on CPIC guidelines
Description: Pitavastatin at the dosage reccomended by the 2022 Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and considerations for Statin-Associated Musculoskeletal Symptoms based on the subjects pharmacogenetic phenotype. A comprehensive description of said doses are can be accessed at: https://cpicpgx.org/guidelines/cpic-guideline-for-statins/