AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06017960 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham dry needling + usual care
Description: Participants assigned to this group will receive the same assessments, the same number of sessions, and the sham dry needling at the same site as the dry needling group, but with a sham intervention, where the needle is dropped through the guide tube and touch the skin. The patient will not feel anything, or at most that the needle touches the skin, since it does not get into the subcutaneous cell tissue, as placebo interventions were performed in similar studies. The context will be simulated in its entirety, using the same ultrasound and disposable needles for the intervention.~Both groups will continue their daily motor rehabilitation treatment during the 4 weeks, which consists of strength training, balance, motor control, gait training, and mass practice oriented to tasks of intensity and duration appropriate to each patient, allowing the fastest possible clinical improvement, as recommended by clinical practice guidelines.
Study NCT05318040 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CMS121
Description: CMS121 is a small molecule to be delivered orally in capsule form and is a therapeutic drug candidate for treatment of Alzheimer's Disease
Study NCT05318040 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be provided as visually matching placebo capsules.
Study NCT04899024 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contingency Management for PrEP Adherence
Description: Participants will complete a 12-week contingency management protocol via their smartphone that consists of uploading brief videos taking PrEP medications up to four times per week. Total possible contingency management incentive for completing 48 observed PrEP doses is $360.
Study NCT04899024 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Contingency Management for PrEP Adherence
Description: Participants will complete a 12-week contingency management protocol via their smartphone that consists of uploading brief videos taking PrEP medications up to four times per week. Total possible contingency management incentive for completing 48 observed PrEP doses is $360.
Study NCT06161415 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Laquinimod eye drops
Description: n Laquinimod eye drops 10 mg/ml Dose: Dosing frequency will depend on the groups assigned
Study NCT05695794 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: the group with a bed head height of 45 degrees
Description: Edema, ecchymosis, respiratory function and sleep quality will be evaluated by giving a 45 degree head height to 30 patients determined by Randomizer.org.
Study NCT05695794 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: the group with a bed head height of 30 degrees
Description: Edema, ecchymosis, respiratory function and sleep quality will be evaluated by giving 30 degrees of bed head height to 30 patients determined by Randomizer.org.
Study NCT05441215 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nirmatrelvir
Description: nirmatrelvir/ritonavir
Study NCT05441215 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ritonavir
Description: nirmatrelvir/ritonavir
Study NCT05766462 — intervention group
Intervention type: OTHER
Intervention: Pacemaker lower rate setting
Description: Pacemaker lower rate is set by physician and may be adjusted according to the physician diagnosis.
Study NCT05509855 — intervention group
Intervention type: GENETIC
Intervention: Genetic: WU-CART-007
Description: No study drug is administered in this study. Patients who have received WU-CART-007 will be enrolled in this study for Long Term Safety and Efficacy
Study NCT06207565 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vestibular Flap Group
Description: Achieving the vestibular flap, a 1-cm long horizontal vestibular access incision using a 15c blade 3-4mm apical to the mucogingival junction of the hopeless tooth, exposing the alveolar bone. Flap dissection in a coronal direction to detach the periosteum is completed, forming a sub-periosteal tunnel.
Study NCT06207565 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Single Flap Approach group
Description: A modified envelope flap originally reported as an access flap for single implant insertion in areas of esthetic relevance will be performed. A sulcular incision on the labial aspect extending at least one tooth mesial and distal to the implant site (permitting enough accessibility for bone augmentation) is done. The flap is reflected by performing a split-thickness flap elevation starting from the interproximal incisions, leaving the anatomical papillae in situ. While the full-thickness flap elevation is performed on the labial aspect of the included surgical area, starting at the sulcus, and reaching at least 3 mm apical to the bone crest.
Study NCT05018910 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Skin to Skin
Description: During routine Skin-to-skin sessions, the heart rate variability of the infant will be measured.
Study NCT05722158 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Dietary supplementation with placebo.
Description: Volunteers will be provided with the placebo. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study NCT05722158 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP1.
Description: Volunteers will be provided with the collagen-derived product CP1. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study NCT05722158 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP2.
Description: Volunteers will be provided with the collagen-derived product CP2. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study NCT06112912 — intervention group
Intervention type: OTHER
Intervention: REAL Essentials Advance
Description: REA is a relationship education curriculum developed by the Center for Relationship Education for high school-age youth. REA teaches youth critical relationship skills and practical approaches for navigating the social dynamics of friendship and love. The curriculum draws on several theories of behavior change, including social cognitive theory, theory of planned behavior, social inoculation theory, social norms theory, and behavior change theory.~REA includes 87 lessons organized into 10 units. The units cover topics such as healthy relationships, effective communication, commitment, planning for the future, job readiness, and sexual health.
Study NCT04840368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dancing
Description: Participants randomized to the dance group will take part in a dance intervention programme for 12 weeks, including 3 sessions per week (non-consecutive days), each lasting 60 min. Dance classes will be performed individually at home, guided by an expertise instructor, as live sessions online. They will include a variety of rhythms such as salsa, merengue, jazz dance, aerobics, etc. The dance sessions will include a warm up of approximately 10 min (posture, join mobility and dance technique), a main part of 40 min (practicing isolated dance moves and learning of specific choreographic routines), and a cool down of 10 min (muscle stretching and relaxation).
Study NCT04840368 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dancing
Description: Participants randomized to the dance group will take part in a dance intervention programme for 12 weeks, including 3 sessions per week (non-consecutive days), each lasting 60 min. Dance classes will be performed individually at home, guided by an expertise instructor, as live sessions online. They will include a variety of rhythms such as salsa, merengue, jazz dance, aerobics, etc. The dance sessions will include a warm up of approximately 10 min (posture, join mobility and dance technique), a main part of 40 min (practicing isolated dance moves and learning of specific choreographic routines), and a cool down of 10 min (muscle stretching and relaxation).
Study NCT05700097 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dengzhanxixin Injection
Description: Experimental arms for low, and high dose for the standard protocol
Study NCT05700097 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo injection
Description: placebo control arm for the standard protocol
Study NCT06264375 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical exercise
Description: see group description
Study NCT06028139 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Continuous glucose monitoring and health coaching
Description: Each CGM device will work for 14 days. The participants will use the CGM devices for the first two-week period in the first three months of the trial, and the first two-week period of the second three months of the trial.~Participants will interact with health coach throughout the study duration.
Study NCT06028139 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: EMPOWER mobile app
Description: Nudges will be delivered through the EMPOWER mobile app. Participants will log lifestyle information such as diet and physical activity, and clinical information such as medication and HbA1c levels through the EMPOWER mobile app.
Study NCT06028139 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EMPOWER mobile app
Description: Nudges will be delivered through the EMPOWER mobile app. Participants will log lifestyle information such as diet and physical activity, and clinical information such as medication and HbA1c levels through the EMPOWER mobile app.
Study NCT05722158 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP3.
Description: Volunteers will be provided with the collagen-derived product CP3. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study NCT05722158 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary supplementation with the collagen-based product CP4.
Description: Volunteers will be provided with the collagen-derived product CP4. For each volunteer, a blood sample from digital puncture will be obtained, and collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS.
Study NCT05994963 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sisunatovir
Description: Administered as either capsules in fasted state or tablet in fasted or fed state.
Study NCT00737542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lidocaine
Study NCT05813613 — intervention group
Intervention type: OTHER
Intervention: Squatting with the aid of Kynapsis Virtual Training apparatus.
Description: Squatting exercise was performed using a virtual reality (VR) machine (kynapsis) for guidance in both groups. Squats were performed while the hands were kept in front of the bodies and the knees flexed to 90 degrees following a rhythm of two seconds for descent, two second ascent mimicking the movement done on the VR machine.
Study NCT04657354 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Assessment
Description: Early surgical assessment
Study NCT05569616 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand massage
Description: Hand massage is a simple comfort intervention that involves touch and conveys care that can easily be incorporated independently into routine nursing care activities. Hand massage is a western technique that includes five basic classical massage manipulations, including eufluorage, petrissage, friction, tapotman and vibration. Kolcaba et al. (2006) hand massage procedure will be applied with baby oil for 20 minutes, three times a week (12 times in total) for 4 weeks.
Study NCT05569616 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Play activity
Description: The number of people for the Jenga game was determined as two people in order to strengthen the social relationship among the elderly and to strengthen their psychomotor skills. Each game will be played with two people. For this reason, the elderly will be divided into five separate groups, two people each.These groups will be played the Jenga game for one hour a week on a certain day of the week, accompanied by the researcher, during the activity hours determined by the nursing home. After the game activity (Jenga) application is completed at the end of the fourth week, the post-test scales will be re-administered to the elderly by the researcher.
Study NCT05117593 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FBL-MTX
Description: FBL-MTX is available as sterile liposomal dispersion for injection at nominal dose strength of 1 mg/mL of methotrexate free base. The dose of 0.1 mg was selected as starting dose in the present study. Three subsequent FBL-MTX dose levels are pre-planned: 0.33 mg, 1 mg and 2.5 mg.
Study NCT05117593 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will consist of sterile saline 0.9% NaCl solution.
Study NCT05825313 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Podcast Using
Description: Students in the experimental group listened to podcast episodes any time they desired following the course every week during the semester from February 2021 to June 2021.
Study NCT06054438 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Chinese medicine nutritional supplement Cs4
Description: Cs4 will be provided by Chinese Pharm, produced by GMP standard manufacturing. The intervention will be given according to the product instruction. Each capsule is 0.4g. According to the product sheet, adults should take 3-4 capsules daily as a way to nourish and strengthen the lungs and kidneys. In our study, the participants are people with long-COVID symptoms. Therefore, in order to achieve maximum efficacy, we will follow the directions and let participants take the maximum amount allowed by the product which is 4 capsules daily. Participants will take one capsule (each 400mg) 4 times a day, for a total of 1.6g. Treatment will last 12 weeks.
Study NCT05210972 — intervention group
Intervention type: RADIATION
Intervention: Cardiac catheterization
Description: All the study population will be exposed to diagnostic coronary angiography and invasive coronary intervention as per standard guidelines.
Study NCT03641430 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Supportive care with OCT product
Description: Participants will apply over-the-counter product for a certain period with or without light challenge. We will perform clinical assessments of the skin associated with product application as well as assess these changes with and without light challenge. Skin biopsies will be obtained following standard medical practice and will be used to analyze skin markers related to photoaging, pigmentation, oxidative stress, and other dermatologic conditions.
Study NCT04655638 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High Flow Nasal Therapy
Description: High flow nasal therapy will be delivered by any device (standalone machine or ventilators able to deliver it). The initial flow rate will be set at 40 L/min and potentially increased up to 60 L/min, according to patient tolerance. Large-bore nasal prongs will be selected according to the size of patients' nostrils (i.e. 2/3 of the diameter of the patient's nostril). A surgical mask will be placed on top of the HFNT interface. The temperature will be set at 37°C or 34 °C according to the patient's comfort. The FiO2 will be adjusted to maintain SpO2 between 92-96%.
Study NCT04655638 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Oxygen Therapy
Description: Conventional Oxygen therapy will be delivered by any device or combination of devices used for delivering oxygen such as nasal cannula, Venturi Mask or Mask with or without a reservoir bag as per usual local practice. Oxygen flow will be titrated to achieve SpO2 between 92-96%.
Study NCT05310890 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai chi training
Description: Tai chi, also called tai chi chuan, is an ancient Chinese form of exercise originally created as a fighting art. It is a kind of gentle physical exercise and stretching, which involves a series of movements performed in a slow, focused manner and accompanied by deep breathing.
Study NCT05310890 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Group activity
Description: A organizer will lead the subjects to participate in group activities once a quarter. In group activities, there will be popular science lectures and interactive games.
Study NCT05310890 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group activity
Description: A organizer will lead the subjects to participate in group activities once a quarter. In group activities, there will be popular science lectures and interactive games.
Study NCT05535023 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR444245
Description: Given by vein (IV)
Study NCT05535023 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: Given by vein (IV)
Study NCT05444907 — intervention group
Intervention type: OTHER
Intervention: No Intervention / Exposure
Description: No intervention / exposure since this is an observational study
Study NCT05841485 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of coronary microvascular dysfunction using intracoronary pressure-temperature wire
Description: The primary assessment method in this study is the measurement of coronary microvascular dysfunction using a pressure-temperature wire to determine coronary flow reserve (CFR) and index of microvascular resistance (IMR).
Study NCT06338371 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pelvic Floor exercise training
Description: The level of sexual function was determined by implementing FSFI for all individuals included in the sample. The participants were divided into two groups, control and training groups, using the randomization program on the computer. Pelvic floor exercise training was given to one group. Trainings were conducted online on different days. Each training lasted 120 minutes. After training was completed, women in the training group were instructed to perform three sets of 8-12 repetitive pelvic floor muscle contractions per day and to use an exercise diary to record their practice. Women in the training group were also given a booklet and the recording of the training video was shared. the training, a brochure explaining how to perform the pelvic floor muscle exercises, which was included in the training content, was prepared and delivered to the training group on the first day of each week. After the training, FSFI was applied to both groups 3 times, in the 1st, 2nd, and 3rd months.
Study NCT04660669 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: ESDM intervention
Description: Early Start Denver Model (ESDM) intervention with remote parental training/ supervision versus intensive ESDM intervention.
Study NCT04660669 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: MOOC
Description: Massive Online Open Course: a teaching and learning intervention based on instrumental and interactive teaching situations
Study NCT06212206 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PillBot
Description: The PillBot System uses active, motorized propulsion technology to facilitate the navigation and positioning of the capsule within the stomach anatomy for imaging of the gastric mucosa by an operator.
Study NCT05218304 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sample
Description: A questionnaire, physical measurements (height, weight, perimeter abdominal and blood pressure) for all arm will be done, approximately 5400 people carried out by investigators. Only 1800 will undergo blood samples carried out by nurses
Study NCT06112067 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: deep brain stimulation
Description: DBS electrodes will be implanted into the ALIC and the NAcc, electric stimulation of those areas are used to treat mental disorders and to evaluate the efficacy and safety of DBS system.
Study NCT00737542 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: NACL 0.9%
Study NCT04991909 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS4800
Description: HRS4800
Study NCT05228080 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: enzyme-linked immunosorbent assay(ELISA)
Description: Peripheral blood samples will be drawn from each patient at study entry (before reperfusion therapy) and at 12,24 hours after reperfusion therapy.Serum will be immediately separated by centrifugation at 3000 rpm for 15 minutes and stored at -80°C. Endocan,ICAM-1,VCAM-1,MMP-9 levels will be determined in duplicate by commercially available enzyme-linked immunosorbent assay (ELISA).
Study NCT05495191 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Signal intensity gradient
Description: In time-of-flight (TOF) MRA, The signal intensities at the iso-point (Φa; signal intensity at position A \[Xa\] along the arterial contour line) and at the inner point (Φb; signal intensity at position B \[Xb\]) were calculated by using a trilinear interpolation algorithm based on the positions and signal intensities in the eight neighboring voxels. The signal intensities of TOF-MRA were normalized to eliminate the offset and scale effects across the MRA datasets of participants. For each iso-point (position A), the SIG was calculated from the difference in signal intensities between points A and B as follows:~Scalar SIG, SI/mm = (Φb - Φa) / │Xb - Xa│ (1)~Vector SIG, SI/mm = (Φb - Φa) n / │Xb - Xa│ (2)
Study NCT06026098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Artificial Intelligence
Description: Participants will use the Artificial Intelligence assistance tool for case reports.
Study NCT04991909 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo