AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06722885 — intervention group
Intervention type: RADIATION
Intervention: Standard radiotherapy treatment
Description: * 3 x 17 Gy for peripheral NSCLC~* 4 x 12 Gy in centrally located NSCLC or at \< 1cm from the thoracic wall~* 8 x 7,5 Gy if with the predefined dose for NSCLC, the constraints of the organs at risk cannot be met~* 5 x 8,5 Gy in case of oligometastases
Study NCT06722092 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: VR-based script training
Description: The PWA will wear a head-mounted VR device (e.g., Metaverse Oculus Quest 2 or other commercially available devices) for 30 minutes, which intends to create an immersive environment for training. Scripts trained in the computerized script training program in a particular session will be practiced. Cinematic 360˚ photo-real scenarios of daily contexts such as a restaurant or a grocery store will be displayed in the device while a communication partner, e.g., a waiter in the restaurant or a shopkeeper of a grocery store will initiate the conversation by producing the corresponding part of the script. The PWA will be given time to respond. Upon the completion of PWA's respond, the next conversational turn will be initiated. The clinical assistant, who accompanies the PWA in the entire training session, will control the flow of the 360 ˚ videos.
Study NCT06722092 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conventional script training
Description: The flow of training is identical to the VR condition, except that photos depicting the scenarios and prerecorded conversational turns will be presented to the PWA on a computer screen with the same procedures mentioned in the VR condition.
Study NCT06723977 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auditory Hallucination Based Voice Hearing Simulation
Description: 1. st stage: Preparation of the environment, introduction, providing information about the purpose, duration and content of the application, application of data collection tools and distribution of the information brochure were provided.~2. nd stage: Introducing the recording devices and headphones, performing the first task simultaneously while listening to the prepared three-dimensional sound recording (watching a city promotional film and answering verbal questions about this film), performing the second task simultaneously while listening to the prepared three-dimensional voice recording (telling a story). (reading the text and answering the questions about this story text in writing) were applied.~3. rd stage: Information about the next application time of the measurement tools was provided.~Additional stage: Data collection tools were reapplied.
Study NCT06725004 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Injection Oxytocin 10 mg intramuscular as trigger for ovulation induction
Study NCT06725004 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Human Chorionic Gonadotropin
Description: Injection Human Chorionic Gonadotropin 5000 IU intramuscular as trigger for ovulation induction
Study NCT06722859 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Open surgical decompression in degenerative lumbar canal stenosis
Description: Open surgical decompression in degenerative lumbar canal stenosis
Study NCT06722859 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Microsurgical decompression
Description: Microsurgical decompression of degenerative lumbar canal stenosis
Study NCT06232005 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mitomycin c
Description: injection of antifibrotic drugs in urethral strictures after internal urethrotomy
Study NCT06232005 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mitomycin c
Description: injection of antifibrotic drugs in urethral strictures after internal urethrotomy
Study NCT04303572 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Eloctate ITI
Description: This is a factor VIII-Fc infusion protein.
Study NCT05230394 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Attended Polysomnography in the Lab
Description: Using standard Level 1 polysomnography
Study NCT05230394 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Unattended Polysomnography in the Home
Description: Using Cerebra's Prodigy system
Study NCT06374576 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lecture on eHealth literacy
Description: There will be a lecture on eHealth literacy. The lecture will be delivered by one well-trained lecturer. , the lecture will be held for old adults in small groups, including a structured curriculum consisting of 4 parts: 5 minutes for the introduction, 40 minutes for the lecture and demonstration, and 40 minutes for hands-on session, 5 minutes for wrapping up. The contents covered in the 40-minute lecture were as follows: 1) smartphone internet basics; 2) introduction of the website prepared for this study; 3) evaluation of the credibility of online health information.
Study NCT06374576 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital intervention on eHealth literacy
Description: 1-week digital intervention, which are multiple messages about the lecture topic will be provided
Study NCT06374576 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Lecture on general health
Description: A lecture session that focus on the general health but not eHealth literacy will be provided
Study NCT06374576 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Digital intervention on general health
Description: 1-week digital intervention, which are multiple messages about the lecture topic will be provided
Study NCT06050486 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mentalization-based treatment for children (MBT-C)
Description: MBT-C is a time-limited intervention designed to resolve the child's emotional or behavioral problems and to promote resilience, by promoting the child's and parent's mentalizing capacities. It is composed by 1) an assessment phase, composed of 3 to 4 sessions, with the family, the child and the parent(s), 2) an intervention phase, composed of a minimum block of 12 individual sessions with the child and parallel sessions for the parent(s), that can be repeated up to three times (i.e., maximum of 36 sessions), and 3) a booster session 3 to 12 months after the last session. In this clinical trial, MBT-C will be composed of: 3 assessment sessions; 12 individual sessions with the child, plus 6 parallel individual sessions with the parent with BPD; 1 booster family session, 3 months after the last session.
Study NCT06236373 — intervention group
Intervention type: OTHER
Intervention: Focus Groups or Interviews
Description: Focus groups and qualitative interview will be conducted with patients, caregivers and stake-holders trying to identify unmet needs of cancer survivors after the acute treatment phase. Individual interviews (in presence or online) will be hold as alternative if it will not be possible (due to logistical or personal problems) to participate in a focus group or if the number of people who would have agreed to participate in that focus group is less than 3
Study NCT04303572 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eloctate ITI
Description: This is a factor VIII-Fc infusion protein.
Study NCT04303572 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Emicizumab
Description: This is a bispecific monoclonal antibody FVIII mimic.
Study NCT05042076 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BK-specific T cells from Donor Lymphocytes
Description: Naturally occurring, allogeneic donor lymphocytes derived from a leukapheresis, enriched for BK-specific CD4+ and CD8+ T cells~Suspension of BK-specific T cells in approximately 7 mL (5-10 mL range for volume of IMP) of 0.9% NaCl with 2.5% HSA at a cell dose of: ≥ 300 and ≤ 5,000 BK virus-specific CD3+ T cells/kg body weight (BW).~IV bolus injection; IV push of IMP over approximately 2-4 minutes, resulting in an infusion rate of approximately 3 mL/min.
Study NCT06397105 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Problem Management Plus
Description: Problem Management Plus (PM+) is a brief, psychological intervention program based on CBT techniques that are empirically supported and formally recommended by the WHO. The full protocol was developed by the WHO and the University of New South Wales, Australia. The manual involves the following empirically supported elements: problem solving plus stress management, behavioural activation, facing fears, and accessing social support. These elements have been recommended in recent WHO guidelines.~Additionally, the original five PM+ sessions will be augmented in two ways. First, the participants will receive three 30-45-minutes telephone booster sessions 10, 22, and 34 weeks after the final original PM+ session. The second augmentation strategy will comprise a digital support program that participants can access via the internet.
Study NCT06397105 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Problem Management Plus
Description: Problem Management Plus (PM+) is a brief, psychological intervention program based on CBT techniques that are empirically supported and formally recommended by the WHO. The full protocol was developed by the WHO and the University of New South Wales, Australia. The manual involves the following empirically supported elements: problem solving plus stress management, behavioural activation, facing fears, and accessing social support. These elements have been recommended in recent WHO guidelines.~Additionally, the original five PM+ sessions will be augmented in two ways. First, the participants will receive three 30-45-minutes telephone booster sessions 10, 22, and 34 weeks after the final original PM+ session. The second augmentation strategy will comprise a digital support program that participants can access via the internet.
Study NCT06547450 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5-session UP condition
Description: Unified Protocol (UP) for transdiagnostic treatment of EDs in 5-session
Study NCT06547450 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: 8-session UP condition
Description: Unified Protocol (UP) for transdiagnostic treatment of EDs in 8-session
Study NCT05196022 — intervention group
Intervention type: OTHER
Intervention: Cochlear implant
Description: G2 will receive a cochlear implant during the study
Study NCT06226038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Magnet disc
Description: Magnetic field promote proliferation and stimulate osteoblast differentiation
Study NCT06226038 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Stainless steel
Description: For control
Study NCT04891523 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: OTHER
Intervention: Probiotics-O (Burgerstein)
Description: Topical oral treatment with the probiotic Streptococcus salivarius K12 (BIOTICS-O, Burgerstein) in form of a lozenge, daily, during 3 weeks.
Study NCT04891523 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Placebo [inactivated Probiotics-O (Burgerstein)]
Description: Topical oral treatment with the placebo \[inactivated probiotic Streptococcus salivarius K12 (BIOTICS-O, Burgerstein)\] in form of a lozenge, daily, during 3 weeks.
Study NCT06160011 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Electrical dry needling + Conventional physiotherapy
Description: Electrical dry needling and conventional physiotherapy treatment (massage, pressure release): 2 sessions
Study NCT06160011 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dry needling + Conventional physiotherapy
Description: Dry needling and conventional physiotherapy treatment (massage, pressure release): 2 sessions
Study NCT06160011 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Conventional physiotherapy
Description: Conventional physiotherapy treatment (massage, pressure release): 2 sessions
Study NCT05303623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physiotherapy
Description: Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day.
Study NCT05303623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Physiotherapy+ inspiratory muscle training
Description: Conventional Physiotherapy to contain breathing and thoracal expansion exercises, bronchial hygiene techniques and gradual mobilization in 1 time a day. In this group addition to conventional physiotherapy inspiratory muscle training will be performed with the threshold-loaded inspiratory muscle training device, starting at 30% of the maximum inspiratory mouth pressure value, during 5 days, in 2 sessions, 4 sets per day, 6-8 breaths in each set and 2 minutes of rest between sets.
Study NCT05303623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: inspiratory muscle training
Description: In this group inspiratory muscle training will be performed with the threshold-loaded inspiratory muscle training device, starting at 30% of the maximum inspiratory mouth pressure value, during 5 days, in 2 sessions, 4 sets per day, 6-8 breaths in each set and 2 minutes of rest between sets.
Study NCT04774263 — intervention group
Intervention type: OTHER
Intervention: Individual interviews
Description: Discussion between the searcher and the participant about representations and acceptability about a potential real time localization system
Study NCT05421481 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: home visit, health education, mobile application, group walk, message
Description: Home visit: Elderly individuals will be visited once at home. During the home visit, training will be given on the slide about physical activity. A brochure will be provided for general health promotion awareness. Counseling will also be provided during the home visit process.~Google Fit Application: During the home visit, the application will be downloaded to the phone of the elderly, and a document will be given about the use of the application after the usage is explained. The researcher will support those who have problems with the application in the following weeks.~Group walking: The walk, which will be done once, will be done in a light paced manner, and the purpose of the walk is to see the number of steps in the mobile application and to increase their motivation with the group.~Message: Message content For your health, you should exercise at least 30 minutes a week for a total of 150 minutes. will be.
Study NCT04379206 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: HIV self-test kit
Description: fingerprick and oral fluid HIV self-tests with optional on-site or hotline staff assistance
Study NCT04379206 — intervention group
Intervention type: OTHER
Intervention: Graphical User Interface
Description: Gamification or neumorphism user interface
Study NCT05612256 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Electrical impedance tomography (EIT)
Description: EIT is the measurement of impedance changes of the lung against the flow of alternating electrical currents applied to the thorax. The signal of the electrodes is transmitted to a monitor, which enables real-time assessment of lung aeration and changes in lung volume. EIT is able to reconstruct impedance changes with a high temporal resolution and allows calculation of tidal volumes, relative stretch of lung tissue and areas of poor ventilation. Areas with impedance changes of \< 10 % of the maximum impedance changes are called 'Silent Spaces'.
Study NCT05612256 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Forced oscillation technique (FOT)
Description: FOT enables non-invasive assessment of lung mechanics using sound waves to inform about the respiratory impedance of the respiratory system (Zrs). Reactance of the respiratory system (Xrs) as part of Zrs is a surrogate measure of compliance of the respiratory system. Xrs was previously used to identify optimal PEEP level, i.e., the PEEP at highest compliance equivalent, in newborn infants using a setup requiring research-specific hardware and software. The FOT module integrated in the commercially available neonatal ventilator is routinely used. FOT measurements are performed twice at each PEEP level to assess the reproducibility of the measurements.
Study NCT05612256 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Saturation oxygenation pressure index (SOPI)
Description: SOPI is assessed non-invasively and calculated from standard monitoring parameters such as PEEP, fraction of inspired oxygen pressure (FiO2) and peripheral oxyhaemoglobin saturation (SpO2) (PEEP x FiO2 x 100) / SpO2). SOPI is used to provide information on ventilation to perfusion ratio dependent on PEEP level.
Study NCT05277311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LongShengZhi capsule
Description: LongShengZhi capsules, orally, 5 capsules each time, three times a day.
Study NCT05277311 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: LongShengZhi capsule placebo
Description: LongShengZhi capsules placebo, orally, 5 capsules each time, three times a day.
Study NCT06221228 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Audio-visual assisted Flipped Classroom (FC) CAPD Training Programme
Description: FC CAPD programme is a one-week individual intervention, which consists of five sessions (8-hours each).~Pre-class audio-visual tutorials will be provided for self-study prior to face-to-face (F2F) sessions. Six instructional videos, each dedicated to a specific procedure, are accessible for preview and repeated viewing as needed. Such flexibility allows the patients to revise at their own preferred time and pace.~Participants will be asked to take note of any issues or difficulties they encounter while watching the video.~A CAPD education booklet will be prepared and distributed to the patients at the beginning of the F2F training session.~Take-home exercises will allow participants to revise the materials covered in the videos and consolidate their learning.
Study NCT05314686 — intervention group
Intervention type: OTHER
Intervention: Five exercise sessions of forty-five minutes within the pulmonary rehabilitation centre and ten days of using a physical activity tracker.
Description: 1. Five exercise sessions of forty-five minutes within the centre on a cycle ergometer using a pulse oximetry device connected to the telerehabilitation system through Bluetooth. Data recorded in the internal memory of the pulse oximeter will be compared with those transmitted through the telerehabilitation system.~2. Ten days of use of a physical activity tracker connected to the telerehabilitation system. Self-reported daily step count by the participants (using a standardized data sheet) will be compared with the daily step count transmitted through the telerehabilitation system.
Study NCT05314686 — intervention group
Intervention type: OTHER
Intervention: Telerehabilitation
Description: An eight-week program including:~* Endurance training on a cycle ergometer (performed independently with remote monitoring or through video conference, according to the participant's preference), three times per week. Training prescription is progressively adjusted using an automated algorithm (aimed to first increase the training duration and then workload intensity).~* Peripheral muscle strengthening using the app (the patient will be requested to reproduce different exercises after watching a video) or through video conference, three times per week (thirty minutes).~* Daily walking with automated coaching.~* Self management education (one to nine sessions according to each individual needs, scheduled through videoconference).~* A self evaluation of symptoms through daily or weekly questionnaires. Different types of alert will be triggered at the center according to remote monitoring: non-adherence, clinical issue during endurance exercise sessions and change in symptoms.
Study NCT05225896 — intervention group
Intervention type: GENETIC
Intervention: Description of clinical characteristic and genetic tumors
Description: This is a non-interventional study involving clinical data and biological samples (DNA). Clinical data are collected for the center and samples are already stored in biobank repositories and collected as part of good clinical practice in the diagnostic process of patients with suspected autoimmune encephalitis, meaning that the standard diagnostic and therapeutic approaches will not be altered in the selected study population. Patients have already gave explicit written consent for biological specimens sampling and storage at the Centre de Ressources Biologiques des Hospices Civils de Lyon (CRB-HCL) (including tissue, cells or biological fluids) and genetic analysis for research purposes. Additionally, patients will be informed about the present study.
Study NCT06290453 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: micro RNA 27- FLP1 gene expression
Description: From each participant, 2 mL of blood will be drawn and store at 25-degree C. The expression of miRNA-27 and FLP1 gene will be measured using real time PCR.~Relative expression values will be normalised to the housekeeping gene GAPDH. The comparative cycle threshold (Ct) approach will be used to measure the relative expression of miRNA 27 and FLP1 gene. Then, using the equation -ΔΔCT, the fold change of each gene will be determined
Study NCT06290453 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: The Expanded Disability Status Scale (EDSS)
Description: The Expanded Disability Status Scale (EDSS) is a way of measuring how much someone is affected by their MS. Neurologists use it to monitor changes in the level of someone's disability over time. The EDSS has a range from 0 to 10.~Zero points is normal neurological examination. 10 points shows the MS-related death cases. Patients with EDSS score up to 5 are fully ambulatory patients.
Study NCT06290453 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Electrophysiological assessment:
Description: Electromyography and nerve conduction velocity will be performed for all MS patients.
Study NCT06290453 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI examination MRI brain:
Description: will be done on all MS patients to detect the number, the site, and the enhancement of lesions