AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04198272 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: CyberRwanda
Description: The CyberRwanda intervention consists of three primary components: 1. STORIES: The CyberRwanda curriculum empowers youth to learn about family planning and reproductive health and employment skills and to set goals for their futures through age-appropriate, interactive, digital and printed stories and activities. 2. LEARN: Q\&As and videos related to family planning and reproductive health. 3. SHOP: Youth can directly purchase health products, including menstrual hygiene and contraceptive products (emergency contraception, condoms, and oral contraceptive pills) online. The online health facility finder tool links youth to health facilities for longer-acting methods. All participating pharmacies will be trained to give unbiased, nonjudgmental information and services.
Study NCT06399640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eltanexor
Description: Eltanexor will be taken by mouth
Study NCT06399640 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax will be taken by mouth
Study NCT06399640 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bone Marrow Aspiration and Biopsy
Description: Undergo bone marrow aspiration and biopsy
Study NCT06399640 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT04342715 — intervention group
Intervention type: DRUG
Intervention: Sodium stibogluconate / paramomycin
Description: Treatment with Sodium stibogluconate / paramomycin
Study NCT06292832 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided pain block
Description: Ultrasound-guided pain block after cesarean section
Study NCT06292832 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Machine
Description: Ultrasound machine used to guide the nerve block.
Study NCT05065008 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cranberry juice
Description: The responders and non-responders will drink 20-30 oz of (590-885 mL) 27% cranberry juice daily for 3 weeks.
Study NCT05065008 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Apple juice
Description: The participants will drink apple juice with matching sugar content and calories for 3 weeks
Study NCT06212934 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Chou's Tiaoshen acupoints includes Baihui (GV-20), Shenting (GV-24), and Sishencong (EX-HN1), Sanyinjiao (SP-6), Shenmen (HT-7) . Using stainless steel needles (0.32×40)mm, HuaTuo, China). Then some other points like, Danzhong(CV-17), Daling(PC-7), Taixi (KI-3), Qihai (CV-6), Taichong (LR3), and Qiuxu(GB-40) are chosen. Operation: Patients in supine position. Baihui (GV-20), Shenting (GV-24), and Sishencong (EX-HN1) are punctured at a depth of 20-25mm obliquely. Sanyinjiao (SP-6) and Shenmen (HT-7) are inserted 15mm perpendicularly. Until feeling tactile sensation then manually manipulated by rotation methods to produce a characteristic sensation known as De Qi; Technique: Mild reinforcing and attenuating, retaining the needle for 30minutes. The treatment will be givenonce a day and 5 times a week in weekdays, the course will last two weeks.
Study NCT06212934 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Estazolam
Description: Participants will take estazolam 1mg 30min prior to bedtime everyday. The course of treatment is two weeks.
Study NCT06111716 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindfulness- Based Childbirth Education
Description: Mindfulness- Based Childbirth Education Group includes; Women were given eight-week birth preparation training. In this training, in addition to information about birth, mindfulness, mindfulness attitudes and practices, mindfulness in daily life, mindfulness in pregnancy and postpartum period, mindfulness breastfeeding and meditation practices were included.
Study NCT06111716 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Information-Based Birth Education
Description: In the Information-Based Birth Education Group, women were given 4-week (4 hours per week) birth preparation training. The education given was not based on a philosophy or method.
Study NCT06535971 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Manual therapy combined exercise
Description: 1. Manual therapy included fascia release, progressive passive stretch, mobilization, etc.(depend on subject's current condition)~2. Exercise included muscle strengthening, trunk (spine) stabilization exercise. (depend on subject's current condition)
Study NCT05476146 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rerouting of the track in high anal fitula
Description: Treatment of high anal fistula by rerouting
Study NCT05909631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Beetroot juice
Description: 250 ml of concentrated beetroot juice, were given to participants in the BJ groups .This was carried out in the morning, 30 minutes before breakfast, and on an empty stomach.
Study NCT05909631 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: 250 ml of a placebo
Study NCT05909631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mediterranean diet alone (MeD)
Description: Mediterranean diet alone (MeD)
Study NCT05909631 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Mediterranean diet with beet juice (BJ+MeD)
Description: Mediterranean diet with beet juice (BJ+MeD).
Study NCT05668728 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group 1: Peppering
Description: Before injection we will palpate the muscles of trapezius, m. rhomboideus, m. levator scapula for finding painful trigger points, and we will mark the point. the skin will be cleaned with an appropriate antiseptic. Before the needle is inserted, the area to be applied will be palpated once again to detect the painful trigger point between the thumb and index fingers. The needle will be guided to painful trigger points detected by palpation. Stainless steel 25x25 mm needles will be used for dry needling. The needle will be inserted and removed until the local twitch response disappears, at least 10 times at each point found. Afterwards, the patient will be given a standard exercise program for the neck muscles. With this method, dry needling will be applied to the patient 4 times a week, once a week.
Study NCT05668728 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: group 2: spin and wait
Description: Just before the injection, painful trigger points in the bilateral muscles of trapezius, m. rhomboideus, and m. levator scapula will be identified and marked by palpation, and the skin will be cleaned with an appropriate antiseptic. Before the needle is inserted, the area to be applied will be palpated once again to detect the painful trigger point between the thumb and index fingers. The needle will be guided to painful trigger points detected by palpation. Stainless steel 25x25 mm needles will be used for dry needling. After the dry needle is inserted at each point found, it will be spinned counterclockwise and left. Waiting time for each patient will be limited to 15 minutes. Afterwards, the patient will be given a standard exercise program for the neck muscles. With this method, dry needling will be applied to the patient 4 times a week, once a week.
Study NCT05668728 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: group 3: Peppering and spin and wait
Description: Just before the injection, painful trigger points in the bilateral muscles of trapezius, m. rhomboideus, and m. levator scapul will be identified and marked with palpation, and the skin will be cleaned with an appropriate antiseptic. Before the needle is inserted, the area to be applied will be palpated once again to detect the painful trigger point between the thumb and index fingers. The needle will be guided to painful trigger points detected by palpation. Stainless steel 25x25 mm needles will be used for dry needling. After the needle is inserted and removed, it will be spinned counterclockwise for 15 minutes in each patient until the local twitch response disappears, at least 10 times at each point found. Afterwards, the patient will be given a standard exercise program. With this method, dry needling will be applied to the patient 4 times a week, once a week.
Study NCT06580132 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Pectin
Description: Pectin fibre (20g) was randomly allocated to eligible participants in order to test specific effects on gut microbiome composition and metabolic markers.
Study NCT06580132 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: Maltodextrin (10g) served as a control/ placebo to compare the effects observed with pectin.
Study NCT05061004 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cephea Mitral Valve System
Description: Transcatheter mitral valve replacement
Study NCT05992142 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: 5-ASA
Description: Assessment of the different levels of remission (clinical, endoscopic, histological) in UC patients treated only by 5-ASA, who report to be in clinical remission during a routine follow-up visit
Study NCT06634745 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Standard Needle Irrigation (SNI)
Description: Standard Needle Irrigation (SNI):~Utilizes standard needle irrigation techniques for activating the antimicrobial solution within the root canal.
Study NCT06634745 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Passive Ultrasonic Irrigation (PUI
Description: Passive Ultrasonic Irrigation (PUI):~Employs ultrasonic energy to enhance the activation and effectiveness of the antimicrobial solution in the root canal.
Study NCT06634745 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: EndoActivator (EA)
Description: EndoActivator (EA):~Uses a sonic activation device to facilitate the distribution and activation of the antimicrobial solution in the root canal.
Study NCT06634745 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: EDDY
Description: EDDY:~Involves the use of a sonic activation device that operates at high frequency to activate the antimicrobial solution within the root canal.~These descriptions focus on the general method and purpose of each intervention without delving into the specific procedural details already covered in the arm/group descriptions.
Study NCT05607108 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ZEN003694
Description: ZEN003694 60mg po qd on a 5 days on 2 days off schedule in an every 21-day cycle
Study NCT04951492 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib
Description: Given PO
Study NCT04531046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: axicabtagene ciloleucel
Description: Patient-specific (autologous) product cryopreserved in cryostorage bag
Study NCT06511232 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraosseous Morphine
Description: More recently, intraosseous infusion of analgesics and antibiotics has gained traction in the total joint arthroplasty literature. In knee arthroplasty patients, the combination of a spine and adductor canal block with an intraosseous infusion of morphine into the tibial tubercle prior to incision yielded lower pain in the immediate postoperative period and at 2 weeks, less pain medication use, and significantly better patient-reported outcomes while also reducing systemic opioid exposure in the early postoperative period compared to the spine and adductor block alone.3 No study to date in the available literature has evaluated the efficacy of intraosseous morphine infusion in managing acute postoperative pain in patients undergoing ACL reconstruction with bone-patellar tendon-bone autograft, so that is the intended evaluation point with this project.
Study NCT06038123 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: China market released 3.0T Magnetic resonance (MR) conditional CIED systems
Description: To confirm safety and effectiveness of the SureScan CIED System in the clinical MRI environment when subjects receive 3.0T MRI scans without positioning restrictions (MRI scans may occur anywhere on the body)
Study NCT06039020 — intervention group
Intervention type: DRUG
Intervention: Anti-human thymocyte immunoglobulin, equine
Description: Usually, 40 mg of anti-human thymocyte immunoglobulin, equine per kilogram of body weight should be slowly administered by intravenous drip infusion once daily. The duration of treatment should be 4 days.
Study NCT06424249 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: A progressive rehabilitation protocol (different levels according to success scores) consisting of several exercises using virtual and augmented reality with mechanical perturbations (pitching of the treadmill), interaction with the virtual environment, interaction with the virtual environment and augmented reality (projection of obstacles on the treadmill), and modification of the gait pattern with visual and/or audio biofeedback
Study NCT06424249 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard rehabilitation
Description: A treadmill walking protocol with virtual reality to immerse the patient in a 3 x 5-minute walking session, without visual, mechanical or auditory disturbances, and without prompting the patient to modify their walking pattern.
Study NCT05240014 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Modular powered orthosis
Description: This study will investigate modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in broad patient populations. The central hypothesis is that high-torque, low-inertia motor systems controlled with energetic objectives will enable modular powered orthoses to partially assist the joints. High-torque electric motors combined with minimal transmissions can be freely rotated (i.e., backdriven) by human joints, allowing the use of an emerging torque control method called energy shaping to reduce the perceived weight/inertia of the body during any motion. By mounting these modular actuators to commercial orthoses, this technology will be easily prescribed/configured by clinicians.
Study NCT05846594 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: FoundationOne® Liquid CDx Assay
Description: Participants will undergo liquid biopsy (FoundationOne® Liquid CDx) on blood samples collected once they have a clinical diagnosis of advanced cancer (as per label). Blood samples will be tested using the FoundationOne® Liquid CDx assay at a central laboratory. Results of the FoundationOne® Liquid CDx assay will be provided to the investigator to be used in accordance with professional guidelines in oncology for patients with malignant neoplasms.
Study NCT05846594 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Standard of Care Diagnostic Pathway
Description: Participants will undergo the local standard of care diagnostic pathway including tissue biopsy/standard of care (if tissue not available), pathology workup, and molecular workup, according to ESMO guidelines or national guidelines for each tumor type included in this study.
Study NCT06636604 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: DSA(Decision Support Algorithm)
Description: Intramuscular injection will be given to 30 volunteer patients using the decision support algorithm.
Study NCT06634446 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a mobile application for cognitive training
Description: Personalized cognitive training (PCT) HappyNeuronwill be delivered via a tablet or mobile application for 24 hours within 12 weeks, with a weekly supervision-call to reinforce their motivation.~HappyNeuron Pro is a digital therapy tool designed for clinicians to provide engaging cognitive therapy via a web-based platform. It is compatible with PC, Mac, iPad, and Android devices and is available in multiple languages. The tool features exercises from established cognitive remediation programs.~Functionality: The program offers 22 cognitive exercises targeting seven key functions outlined in the MATRICS framework: Processing Speed, Selective Attention, Reasoning and Working Memory, Verbal Memory, Visual Memory, and Auditory Memory. Exercises are customizable to meet individual patient needs, facilitating personalized cognitive training.~User Experience: Each session comprises brief, self-administered exercises, with the order and difficulty adjusted by clinicians.
Study NCT06634446 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: video games
Description: Patients in the control group will use video games with no prominent cognitive involvement no prominent cognitive involvement
Study NCT06539403 — intervention group
Intervention type: BEHAVIORAL
Intervention: Memory tasks
Description: Naturalistic Episodic Memory encoding: Participants will play short sessions of 3 board games with the researcher. The board games include Ludo, Snakes \& Ladders and Solitaire. Participants will play each boardgame for around 5 min. They will wear a head camera while playing the games.~Later participants will be tested on their memory of the naturalistic episodic memory task, a semantic memory task (memory of facts) and a perceptual task. Each task will consist of 2-3 sub-tasks of around 30 trials. These tasks will all take place on the computer and will take 30-40 minutes in total. In each trial participants will choose between two options. For example: Which of these two images is taken from your head camera? What colour piece did you use in 'snakes and ladders'?. After they choose their answer, they will report how confident they are in their choice. At the end of each task, they will be asked to report how well they think they performed on the task overall.
Study NCT05602363 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docirbrutinib
Description: oral tablet, twice daily
Study NCT05899673 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fazirsiran Injection
Description: Fazirsiran will be injected subcutaneously.
Study NCT06509737 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Face to face group
Description: With this research, it is expected that parents' knowledge levels, symptom management levels for food allergies, and treatment knowledge levels will increase by providing Life with Food Allergy Training based on the Health Promotion Model with face-to-face training in parents of children diagnosed with food allergy.
Study NCT06509737 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: social mediagroup
Description: With this research, it is expected that parents' knowledge levels, symptom management levels for food allergies, and treatment knowledge levels will increase in parents of children diagnosed with food allergy by providing Life with Food Allergy Education based on the Health Promotion Model through social media.
Study NCT05721014 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: OsteoStrong
Description: This training method is an isometric high-impact loading in four different training machines (Spectrum) and balance training on a vibration plate. The four machines are chest press, leg press, pull-down and deadlift. The participants press and/or pull isometrically for around 10-15 seconds 1-3 times on every machine.~The training session takes around 20 minutes and is performed individually by the participants with the help of a training instructor.
Study NCT05721014 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Individually Adapted and Combined Physical Training
Description: This training method is based on the current recommendations on physical activity for people with osteoporosis.~The training is divided into two training sessions:~Circuit training with ten stations with different exercises for the whole body (strength, balance, endurance, weight-bearing). The participants spend 40 seconds on each station. This is repeated during 40 minutes. The training session starts with a joint warm-up and ends with a cool-down.~Strength training with machines for the whole body with the intensity of up to 70-80 % of one repetition max (1RM). The training session starts with a joint warm-up and and a voluntary individual cool-down.~The training session takes around 60 minutes and is performed in a group with the help of a training instructor. The participants also have the option to do a home based exercise programme that they could do in a few cases when they were unable to attend the physical group training.
Study NCT06580574 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD1/PDL1 antibody monotherapy, up to 24 weeks
Description: non-specific, according to Drug Instructions
Study NCT06580574 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Intensive immunotherapy plus anti-VEGF treatment, up to 24 weeks
Description: Sintilimab 200mg, ivgtt, q21d; IBI310 1mg/kg, ivgtt, q42d; Lenvatinib 8mg (starting from 4mg), po, qd
Study NCT06580574 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radical surgery
Description: Radical surgery will be recommended per local treatment standards.
Study NCT05010148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine IV
Description: Intravenous lidocaine will be given at 1.33mg/kg/hr (adjusted body weight) for 48 hours following major spinal surgery
Study NCT05010148 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: D5 water given at an equivalent ml/hr as intravenous lidocaine (treatment arm) for 48 hours following major spinal surgery
Study NCT06647095 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: D-Limonene Gelcaps
Description: Capsules containing d-Limonene will be optionally given during the breath test to all participants of all groups
Study NCT06647095 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Intervention: Fish Oil Concentrate, 1000 Mg Oral Capsule
Description: Capsules containing fish oil will be optionally given during the breath test to all participants of all groups
Study NCT06305754 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sacituzumab tirumotecan
Description: 4 mg/kg via IV infusion
Study NCT06305754 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pemetrexed
Description: 500 mg/m\^2 via IV infusion