AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05087030 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prolia®
Description: Participants will receive Prolia® into the thigh, abdomen, or upper arm as per the arm assigned.
Study NCT05327062 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
Description: The following information and data will be obtained from the routine clinical work up of the patients: Patient demographics, cardiovascular medical history, and clinical examination; 12-lead ECG; Standard echocardiography; Computed tomography angiography for visualization of atria, ventricle, and coronary sinus.~Imaging data will be transferred to the cloud-based web-platform using a dedicated software provided by study sponsor. Data processing includes evaluating the quality of the data and calculation of various anatomical and electrical parameters, and identification of the target zone as a point in the target vein closest to the latest activation zone.~LV-lead location is based on the information provided by the dedicated software followed by visual X-ray based verification of anatomically suitable/most desirable position.~The patient will undergo CRT device implantation according to local protocols.
Study NCT04576442 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Asthma-PASS
Description: The investigator will collaborate with the student's primary care provider (PCP) by sending a letter via facsimile, and/or email to ensure appropriate medications are prescribed or adjusted and rescue medications are available at school. Community Health Workers (CHWs) will follow up with PCPs as needed to provide reminders about prescriptions for controlled medications and to ensure a MAF is provided to schools to allow rescue medication administration by nurses. CHWs will work with local pharmacies when possible to have prescribed medications delivered to schools and homes. For students without a PCP, we will refer families to one of Montefiore Medical Center's 20 practices throughout the Bronx. For students without medical insurance or who are unable to go to a Montefiore clinic, the NYC DOE physicians who routinely attend NYC schools will provide medical care and prescribe appropriate medications.
Study NCT04576442 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Basic Asthma Management (AM)
Description: PCPs and caregivers will be notified that children in the AM group have persistent/uncontrolled asthma that warrants use of guideline-based preventative medications.
Study NCT06427343 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High-dose ferric derisomaltose
Description: After baseline assessment, participants will be randomized in a 1:1 ratio to receive a high-dose IV iron regimen and a low-dose IV iron regimen. After the initial iron repletion, ferritin concentration and TSAT were measured every three months and the results used to determine the dose of ferric derisomaltose during follow-up.~In the high-dose group, participants will receive repeat iron dosing as long as the serum ferritin was not >700 ng/mL, or if TSAT was not >40% during follow-up.
Study NCT06427343 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Low-dose ferric derisomaltose
Description: In the low-dose group, participants will receive repeat iron dosing if ferritin \<100 ng/mL or if ferritin 100-300 ng/mL and TSAT >20% during follow-up.
Study NCT05212129 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous vagal nerve stimulation (pVNS) device
Description: Subjects in Treatment Arm B will enter a six-week, prospective open label treatment trial with the FDA-approved and commercially available device IB-Stim. This is an ambulatory, neurostimulation device which consists of a battery powered, externally affixed generator with 4 wire leads attached to electrode/needle arrays affixed to the outer ear. The device delivers low voltage (3.2V) stimulation in alternating frequencies for a total of 5 days (around the clock).
Study NCT05212129 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Acoustic vagal nerve stimulation (aVNS) treatment
Description: All subjects receiving acoustic therapy via active VNS (aVNS; n=30) or sham VNS (sVNS; n=30) will enter a four-week, randomized, double-blind clinical trial during which they will listen to either computer altered/filtered vocal music (active treatment) that has been designed to stimulate vagal calming vs. regular non-filtered music (sham treatment). The stimuli will mirror the acoustic intervention known as the Safe and Sound Protocol. This protocol has been found to reduce auditory hypersensitivities and calming the autonomic nervous system by increasing vagal regulation of the heart via brainstem ventral vagal complex. The acoustic intervention may be played by an electronic device (i.e. smartphone, tablet, laptop, mp3) and delivered virtually with the help of trained coaches.
Study NCT06363188 — intervention group
Intervention type: DEVICE
Intervention: Radial Extracorporeal shockwave
Description: a device used by physiotherapist to treat various musculoskeletal problems and it was here firstly used to accelerate the bone healing process after bone fracture
Study NCT05409560 — intervention group
Intervention type: OTHER
Intervention: Swimming participants in the 6-hour cold water swim
Description: The 6-hour cold water swim was the qualifying swim for the English Channel swim during the Channel Swim Camp Dinard 2021 and participants were the swimmers registered for the 6-hour cold water swim who volunteered to participate in this study
Study NCT04576442 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Child/Caregiver Education session
Description: The investigator will provide in-school child asthma education sessions delivered by trained, bilingual (English-Spanish) Community Health Workers (CHWs) using an established manualized protocol from past and current studies designed to improve knowledge and self-efficacy. Each child will receive two 1-on 1, 20-minute developmentally appropriate educational sessions at school 3-4 weeks apart. Sessions will cover: 1) asthma basics, symptoms and triggers; and 2) medications and correct administration technique. Caregivers will be called after each child session to highlight key points reviewed with the child and answer questions.
Study NCT04576442 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Child/Caregiver Education session
Description: The investigator will provide in-school child asthma education sessions delivered by trained, bilingual (English-Spanish) Community Health Workers (CHWs) using an established manualized protocol from past and current studies designed to improve knowledge and self-efficacy. Each child will receive two 1-on 1, 20-minute developmentally appropriate educational sessions at school 3-4 weeks apart. Sessions will cover: 1) asthma basics, symptoms and triggers; and 2) medications and correct administration technique. Caregivers will be called after each child session to highlight key points reviewed with the child and answer questions.
Study NCT05005884 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral intake of medication
Description: Prescription of oral phenolics 250 mg two times daily
Study NCT05005884 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Prescription of oral phenolics 250 mg two times daily
Study NCT04740411 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Common Elements Toolbox (COMET)
Description: COMET is an online unguided self-help intervention that lasts approximately 60-80 minutes.
Study NCT03240900 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electrical Stimulation
Description: Electrical stimulation - a needle attached to an cathode polarity will be placed within the intercostal space near the 4th intercostal nerve. A second needle attached to the anode polarity will be inserted into the serratus anterior muscle. Both electrodes will then be attached to a Grass SD9 stimulator and the voltage and frequency of the stimulation will be titrated to the point where contraction of the intercostal muscles is palpable. It will be maintained at this level for one hour at which point the wires will be removed. This technique is part of the standard of care for peripheral nerve surgeries of the extremities and is proven to be safe in humans.
Study NCT03240900 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: This breast will receive no electrical stimulation; the mastectomy and reconstruction will proceed with no intervention.
Study NCT04444570 — intervention group
Intervention type: DEVICE
Intervention: Continuous glycemia measuring device (Dexcom) implantation into the subcutaneous tissue
Description: 14 days before the date of the surgery and after the surgery patient will have implemented the device for continuous glycemia measurement (Dexcom). During standard control visit 14 days after the surgery for skin sutures removal the device will be taken out and data of whole period of time will be collected
Study NCT04879602 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: suction with bronchoscopy
Description: suction with bronchoscopy
Study NCT05162807 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychoeducational Video on Palliative Care
Description: The intervention is a psychoeducational video introducing palliative care and discussing its purpose, structure, benefits, and efficacy.
Study NCT05162807 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Educational Video on Nutrition
Description: The attention control is a video on nutrition and healthy eating during cancer survivorship.
Study NCT05238051 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Gastric residual volume measurement stopped.
Description: GRV is checked during routine enteral nutrition, but we think that GRV prolongs the time to reach target calories and does not reduce complications.
Study NCT05323851 — intervention group
Intervention type: BEHAVIORAL
Intervention: COVID-surg-SPIGC questionnaire
Description: The questionnaire aimed to evaluate how the COVID-19 pandemic determined a shift in daily practice through a multidimensional assessment of surgical clinical care in three different time frames.
Study NCT06305039 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Diagnostic tests of cochlear implant or acoustic hearing function
Description: Because the cochlear implant participants in the study will use cochlear implant devices that they have already received as part of their standard-of-care treatment, the medical device itself is not an intervention for the purposes of this study. The intervention here will be to carry out diagnostic tests of cochlear implant or acoustic hearing function. This will include perceptual tests of sound localization, speech understanding in noise, binaural fusion, and loudness comparisons.
Study NCT06305039 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Diagnostic tests of cochlear implant or acoustic hearing function
Description: Because the cochlear implant participants in the study will use cochlear implant devices that they have already received as part of their standard-of-care treatment, the medical device itself is not an intervention for the purposes of this study. The intervention here will be to carry out diagnostic tests of cochlear implant or acoustic hearing function. This will include perceptual tests of sound localization, speech understanding in noise, binaural fusion, and loudness comparisons.
Study NCT06305039 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted aural rehabilitation of the poorer performing ear
Description: Subjects will undergo listening practice on a tablet computer over headphones at home. For the test group, the aural rehabilitation will be targeted at the poorer ear. For the comparison control group, a sham aural rehabilitation will present speech to both ears.
Study NCT05982951 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Shoulder PENG block
Description: Ultrasound guided insertion of a needle between subscapularis tendon and deltoid with injection of 10 mi 0.25% bupivacaine after confirming right plane of injection
Study NCT05420753 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transjugular Intrahepatic Portosystemic Shunt (TIPS) creation
Description: During a TIPS procedure, the interventional radiologist, with the help of x-ray and ultrasound guidance, makes a channel through the liver to connect the portal vein (the vein that carries blood from the digestive organs to the liver) to one of the hepatic vein (three veins that carry blood away from the liver back to the heart) using a special type of needle. The interventional radiologist then replaces the needle with a wire and catheter, and a small tubular device called a stent graft is placed in this channel to keep the pathway open between the two blood vessels.
Study NCT05283837 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pertuzumab (ZRC-3277)
Description: Pertuzumab in combination with Trastuzumab and Docetaxel will be administered via intravenous (IV) infusion every 3 weeks for 06 cycles.
Study NCT05283837 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pertuzumab (Perjeta®)
Description: Pertuzumab in combination with Trastuzumab and Docetaxel will be administered via intravenous (IV) infusion every 3 weeks for 06 cycles.
Study NCT05309850 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle tool
Description: Regular use of the digital Lifestyle tool
Study NCT05409105 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mangoes
Description: Frozen mangoes, 2 cups per day, 2 weeks
Study NCT05409105 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Water
Description: 2 cups/day bottled water, 2 weeks
Study NCT04848493 — intervention group
Intervention type: BIOLOGICAL
Intervention: COVID-19 vaccines
Description: This is an observational prospective study whose general objective is to assess the impact of COVID-19 vaccination in terms of induction of humoral and cell-mediated immune responses in selected fragile (altered immunocompetence) populations.
Study NCT00013078 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Physical restoration intervention
Study NCT06249529 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Airway Bypass
Description: Bypass stent(s) are implanted to allow air trapped in the parenchyma to escape
Study NCT04903977 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Laboratory tests: blood and faeces tests
Description: To be performed at V2
Study NCT04903977 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Gynaecological and proctological examinations
Description: To be performed at V1 (Examination with a gynaecological speculum, Bimanual examination, Rectal examination, and Anoscopy)
Study NCT04903977 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 3-D Endoanal Ultrasound
Description: To be performed at V1 (as a reference and for group assignment)
Study NCT04903977 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ONIRY measurement
Description: To be performed at V2 (the electrical impedance of anal sphincter muscles will be measured)
Study NCT04903977 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: High-resolution anorectal manometry
Description: To be performed at V3
Study NCT04903977 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: ECG
Description: To be performed at V1 and V2 (for safety reasons)
Study NCT05532696 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABT-101
Description: Patients will receive ABT-101 by oral administration on a 28-day cycle
Study NCT04814238 — intervention group
Intervention type: PROCEDURE
Intervention: Aortic Root Surgery
Description: First time, isolated, minimally invasive (mini-sternotomy, RALT) aortic root or aorta surgery
Study NCT05384977 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-NV-5138
Description: Single dose, given as oral solution, 1600 mg
Study NCT05054660 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: caring chatbot
Description: The investigators will use the developed caring chatbot to provide care to the cases and to collect case treatment data and interaction data between the case and the caring chatbot.
Study NCT05391191 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MitrAssist TRISKELE® transcatheter aortic valve system
Description: Patients were treated with MitrAssist TRISKELE® transcatheter aortic valve system
Study NCT06104839 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NXC736
Description: oral administration
Study NCT06104839 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral administration
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo beverage, kiwi-strawberry flavor (Part 1 and Part 2)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 0% carbohydrate electrolyte solution with glycerol beverage (Part 1 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 0% carbohydrate electrolyte solution without glycerol beverage (Part 1 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 1% carbohydrate electrolyte solution with glycerol beverage (Part 1 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 6% carbohydrate electrolyte solution with glycerol beverage (Part 1 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 6% carbohydrate electrolyte solution without glycerol beverage (Part 2 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT06654557 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 6% carbohydrate electrolyte solution with glycerol beverage (Part 2 only)
Description: 9.3 oz (276 ml) aliquots 3 times for a total of 28 oz (828 ml) over a 35 min period followed by 25 min rest until Time 0 post-dose. Beverage matched to placebo for color and flavor.
Study NCT05766748 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azeliragon
Description: Azeliragon is an orally administered inhibitor of Receptor for Advanced Glycation Endproducts (RAGE) which is formulated as a 5mg hard gelatin capsule.
Study NCT06654648 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Combined exercise nutrition intervention group
Description: Combination Product: Combined exercise and nutrition intervention Combined exercise and nutrition intervention for 12 weeks (an introductory phase 3 weeks, an expanded phase 3 weeks, and a maintenance phase 6 weeks). Exercise intervention (each 60-min session) includes stretching, resistance exercise, and aerobic exercise according to protocol. Nutritional intervention includes investigating dietary habits and calculate insufficient protein intake using Mini Nutritional Aseessment (MNA) and Korean Protein Assessment Tool (KPAT) to provide customized diet and high protein drink.
Study NCT04736589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Inetetamab
Description: Initial dose of 8mg/kg, completed in 90 minutes IV infusion, and then 6 mg/kg over 30-90 minutes IV infusion every 3 weeks.
Study NCT06654648 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional medial care group
Description: Conventional medial care Conventional medical care service for 12weeks during intervention period. Usual care includes medical check-up and exercise and dietary counseling. They were given a brochure about exercise and protein rich foods at their first visit.~The control group patients maintain their usual amount of activity and diet during the 6-month evaluation period. usual activity and dietary habits.
Study NCT04687722 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Aerobic Training.
Description: Participants will perform 2-5 minutes of low to moderate intensity warm up exercises and then 20 minutes of high intensity aerobic training at 80-90% of heart rate maximum increased gradually on treadmill and elliptical trainer and then 2-5 minutes of low to moderate intensity cool down exercises.
Study NCT04687722 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low intensity Aerobic Training
Description: Participants will perform 2-5 minutes of low to moderate intensity warm up exercises and then 20 minutes of low intensity aerobic training at 40-60% of heart rate maximum increased gradually on elliptical trainer and jogging and then 2-5 minutes of low to moderate intensity cool down exercises.
Study NCT05169905 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: RSV MAT vaccine
Description: Single dose of the RSV MAT vaccine reconstituted with NaCl solution was planned to be administered intramuscularly, in the non-dominant arm, at Day 1 or at Day 31, depending on the vaccination schedule.~RSV MAT vaccine was no longer administered to participants at Day 31. No vaccine was administered in the dTpa_RSV-P Group, since there were no participants assigned to it.