AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05596227 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Fentanyl
Description: Fentanyl will be injected during the induction of anesthesia (1-1.5 mg/kg)
Study NCT05596227 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rocuronium
Description: Rocuronium will be injected during induction of anesthesia (0.6 mg/ kg)
Study NCT05596227 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rocuronium
Description: Rocuronium will be injected during induction of anesthesia (0.6 mg/ kg)
Study NCT05596227 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Sevoflurane inhalationa anesthesia will be used for maintainance of anesthesia
Study NCT05596227 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sevoflurane
Description: Sevoflurane inhalationa anesthesia will be used for maintainance of anesthesia
Study NCT05596227 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Erector spinae plane block
Description: In the ESPB group, the probe will be placed in the parasagittal plane at the level of the L3 vertebrae. The spinous process will be visualized, and the probe will move 3 cm laterally from the midline. The erector spinae muscle will be visualized above the transverse process. The needle will be punctured in the craniocaudal direction using the in-plane technique. The needle will be directed superior to the transverse process . Then, 2 mL normal saline solution was injected into the deep fascia of the erector spinae muscle to confirm the proper injection site. After ensuring the location of the needle, 20 mL of 0.25% bupivacaine was administered. The same ESPB procedure will be performed on the other side. In total, 40 mL of 0.25% bupivacaine was administered.
Study NCT05596227 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Thoracolumbar interfascial plane block
Description: In the mTLIP group, the probe will be placed vertically at the L3 vertebrae level. The spinous process and the interspinous muscles (i.e., multifidus, longissimus, and iliocostalis) will be visualized as the anatomic guide points. The probe will move laterally to identify the longissimus and iliocostalis muscles. The needle will be inserted between the longissimus and iliocostalis in the medial-to-lateral direction using the in-plane technique. After confirming the location of the needle, 20 mL of 0.25% bupivacaine was administered. The same mTLIP procedure will be performed on the opposite side. In total, 40 mL of 0.25% bupivacaine will be administered.
Study NCT04925622 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Complex eye movement exam
Description: Subjects will undergo a complex eye exam which will capture fixation, optokinetic nystagmus, guided saccades, microsaccades, smooth pursuit, and pupillometry.~Eye tracking equipment will be set and calibrated to the participant who will then perform the full 10 minute testing protocol with instructions from the investigator. After this, they will take a five minute break. The oculomotor testing protocol will be repeated twice.
Study NCT06567834 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150)
Description: Multifocal IOL with violet light filtration and high-resolution lathing
Study NCT06567834 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)
Description: Multifocal IOL with ultraviolet filtration
Study NCT04220723 — intervention group
Intervention type: OTHER
Intervention: Frailty Assessment
Description: Liver Frailty Index measurements:~1. Grip strength: the average of three trials, measured in the subject's dominant hand using a hand dynamometer~2. Timed chair stands: measured as the number of seconds it takes to do five chair stands with the subject's arms folded across the chest~3. Balance testing: measured as the number of seconds that the subject can balance in three positions (feet placed side-to-side, semitandem, and tandem) for a maximum of 10 seconds each.
Study NCT04220723 — intervention group
Intervention type: OTHER
Intervention: Functional Capacity Assessment
Description: Shuttle Walk Test: The patient is required to walk around two cones set 9 metres apart (so the final track is 10 metres) in time to a set of auditory beeps played on a CD. Initially, the walking speed is very slow, but each minute the required walking speed progressively increases. The patient walks for as long as they can until they are either too breathless or can no longer keep up with the beeps, at which time the test ends. The number of shuttles is recorded. Each shuttle represents a distance of ten metres (i.e each time the patient reaches a cone is 1 shuttle).
Study NCT06362369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alintegimod
Description: Alintegimod will be provided in bottles of 30 softgel capsules for oral administration
Study NCT05439850 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: arthroscopic rotator cuff repair
Description: This procedure is the standard of care for rotator cuff tears who fail conservative treatment options.
Study NCT06362369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Ipilimumab (Yervoy) will be administered via IV
Study NCT06362369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Nivolumab (Opdivo) will be administered via IV
Study NCT05560230 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Clonidine
Description: A single dose of intraoperatively administered intravenous clonidine 150 μg will be infused over 5-10 min., immediately after intubation
Study NCT05560230 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Isotonic saline
Description: A single dose of administered intravenous isotonic saline will be infused over 5-10 min., immediately after intubation
Study NCT04969991 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Varespladib
Description: 250 mg immediate-release oblong, white, film-coated tablet for oral administration
Study NCT05439850 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: arthroscopic rotator cuff repair
Description: This procedure is the standard of care for rotator cuff tears who fail conservative treatment options.
Study NCT04969991 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral formulation matched to the oral varespladib tablet
Study NCT04969991 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Oral formulation matched to the oral varespladib tablet
Study NCT05439850 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bioinductive implant
Description: A bioinductive implant that is designed to promote healing of the torn rotator cuff tendon after surgery.
Study NCT05439850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Imaging
Description: An ultrasound will be performed on each patient one year postoperatively.
Study NCT05439850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound Imaging
Description: An ultrasound will be performed on each patient one year postoperatively.
Study NCT04835402 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 400mg every 6 weeks
Study NCT04835402 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Irreversible electroporation
Description: Percutaneous ablation of one liver metastasis
Study NCT05836610 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hydrocortisone
Description: intravenous bolus hydrocortisone therapy during hypothermia treatment
Study NCT05935930 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol 10 MG/ML Injection
Description: Propofol infusion
Study NCT05935930 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane Inhalation Liquid
Description: Sevoflurane inhalation
Study NCT06509542 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Objective assessment of upper limb use during activities in ecological situation
Description: Twenty-five patients will be recorded performing three activities during their rehabilitation: getting dressed, preparing a meal, and eating a meal. The movements of their upper limbs will be tracked using wrist-worn accelerometers and video cameras.
Study NCT03994991 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active TMS
Description: Transcranial magnetic stimulation
Study NCT03994991 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham TMS
Description: Sham transcranial magnetic stimulation
Study NCT06262360 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General anesthesia with mask ventilation
Description: Randomization to General anesthesia with mask ventilation
Study NCT06262360 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General anesthesia and spontaneous laryngeal mask ventilation
Description: Randomization to General anesthesia and spontaneous laryngeal mask ventilation
Study NCT06262360 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General anesthesia with spontaneous laryngeal mask ventilation with pressure support
Description: Randomization to General anesthesia with spontaneous laryngeal mask ventilation with pressure support
Study NCT04729634 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Mobilization
Description: Mobilization and breathing exercises according to clinical care
Study NCT05676164 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KANG XIAN
Description: This product is a liquid composed of silica, stabilizer, xylitol, flavoring agent and water. The pH value of the product is 5.0 \~ 8.0, and the total heavy metal content (measured by Pb2+) is less than 10µg/ml.
Study NCT05676164 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: TIAN XIA
Description: The products are dark yellow granules made from rice, soybean, lotus root powder, orange peel, coix seed and yam.
Study NCT05879146 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nirogacestat
Description: Given by PO
Study NCT05380661 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Self-catheterization
Description: Participants will perform self-catheterization, following the same routine for intermittent catheterization at home
Study NCT05380661 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Catheterization performed by urology nurse, participant blinded to time of procedure
Description: Participant will undergo procedure to completely empty bladder; Participant in supine position, and resting blood pressure and heart rate will be recorded for period of 5 minutes prior to catheterization; Perineum and genital areas will be draped and they will be not aware about exact timing of catheterization Catheterization will be conducted following standard clinic procedure by experience urology nurse.
Study NCT05380661 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Catheterization performed by urology nurse, participant aware of time of procedure
Description: Participant will undergo procedure to completely empty bladder; Participant in supine position, and resting BP and HR will be recorded for period of 5 minutes prior to catheterization; Perineum and genital areas will be visible to participant and they will be fully aware about exact timing of catheterization Catheterization will be conducted following standard clinic procedure by experience urology nurse.
Study NCT06032286 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Skinstylus microneedling device
Description: Microneedling, also known as percutaneous collagen induction (PCI), is a minimally invasive technique where small needles create microscopic wounds in the skin inducing collagen formation.
Study NCT05015491 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Noom Healthy Weight Program
Description: The Healthy Weight program follows guidelines from the Obesity Society's 2013 Guidelines for the Management of Overweight and Obesity in Adults NIH Practical Guide on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. Users are encouraged to log their weight (Weight Logging) at least 1x/week and log their food and beverages (Food Logging) daily. Exercise logging (steps via automatic collection or manually added) is done daily. The Noom Food color grading system is founded on calorie-density (Volumetrics diet, Barbara Rolls) and is a simple and effective method for creating long lasting changes in diet and food choice. Coaches are contacted via In-app messaging or phone communication.
Study NCT05225181 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: perform physical exercise
Description: one 60-min session of physical training
Study NCT05225181 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive training
Description: one 60-min session of cognitive training
Study NCT05225181 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: control group
Description: perform body stretching(15min) and health education courses(90min)
Study NCT04995640 — intervention group
Intervention type: PROCEDURE
Intervention: open cardiovascular repair or endovascular treatment (TEVAR)
Description: Surgery type: open cardiovascular repair and endovascular treatment (TEVAR)
Study NCT06382857 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MDF
Description: MDF will be provided to children on a weekly basis for children with SAM and bi-weekly basis for children with MAM at the health center until programmatic recovery but not thereafter.
Study NCT06382857 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: RUTF
Description: RUTF will be provided to all children on a weekly basis at the health center until programmatic recovery but not thereafter
Study NCT06382857 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: RUSF
Description: RUSF will be provided on a biweekly basis at the health center until programmatic recovery but not thereafter
Study NCT06034821 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Subanesthetic dose intravenous ketamine (KET)
Description: This trial will use standard dose of ketamine (0.5mg/kg infusion over 40 min period) in accordance with research studies that have used ketamine as an antidepressant. Treatments will be given two times a week for a maximum of 8 treatments during the acute arm of the study. The investigators will be able to modify dose and number of treatments as indicated clinically per pragmatic clinical trials procedures. Patients will be clinically assessed prior to each treatment to evaluate response and appropriateness of continuation of treatment. Per FDA guidelines a maximum 60mg/dose will be given regardless of body weight.
Study NCT06034821 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electroconvulsive therapy (ECT)
Description: ECT will be given in a standard manner 3 times a week for 4 weeks. The Initial ECT treatment will be Right Unilateral (RUL) ultra-brief pulse at 6x seizure threshold determined during titration at first visit. If there is not satisfactory improvement with RUL the investigator may change to Bilateral (BL) utilizing brief pulse using 0.5 modified half-age method to determine stimulus intensity. The seizure threshold may increase during the course of treatment and the dose of the electric stimulus may need to be increased incrementally. It is suggested to change to bilateral after three to five RUL treatments if response to treatment is not satisfactory. Treatments will be given three times a week for up to 4 weeks.
Study NCT03945305 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Patients are treated with previous antihypertensive treatment plus remote ischemic conditioning.
Description: Remote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 200 mmHg.
Study NCT06197698 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: F18-FDG, Tc-99m TRODAT-1
Description: In this project, 18F-FDG PET is used as an imaging marker of gut microbiota composition evaluation in PD patients, and the nigrostriatal dopamine system is assessed by Tc-99m TRODAT-1 SPECT.
Study NCT05698693 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep intervention
Description: The sleep extension intervention is a 4-week intervention consisting of weekly one-on-one contact with the goal of increasing total sleep time by 60 minutes by the end of four weeks conducted by Dr. Wu or a trained counselor.
Study NCT05698693 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Contact Control
Description: This is healthy homes intervention.The program provides education on healthy homes, provide advice on specific healthy homes problems, and recommend actions to be taken by families, landlords, and community members.
Study NCT04359888 — intervention group
Intervention type: OTHER
Intervention: Multi-Modality Balance Intervention
Description: Three one-hour training sessions 2-3x per week for six weeks in Multi-Modality Balance Intervention (MMBI). (See Study Design)
Study NCT04359888 — intervention group
Intervention type: OTHER
Intervention: Balanced Reach Training (BRT)
Description: One-hour training sessions 2-3x per week for six weeks in the Balanced Reach Training Protocol (BRTP) (See Study Design).
Study NCT05923541 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RD13-02 cell infusion
Description: Universal CAR-T cells targeting CD7
Study NCT05428267 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: questionnaire
Description: Completion of questionnaires (IIEF5/FSFI, SF 36, Fatigue Scale Score, Self Esteem Inventory, Hospital Anxiety and Depression Scale) during the pre-transplant consultation, then during a consultation 6 months after transplantation
Study NCT05428267 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: blood collection
Description: Collection of 2 tubes of 5mL of blood during a scheduled blood draw in the patient's care pathway. This sample will also be taken after the transplant (6 months later)
Study NCT06649175 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Close kinetic chain (CKC) exercises :~1. Supine wall push exercise: Start position: supine with the both leg against wall, other limb straight. Exercise action: push against wall for thirty seconds.~2. Wall push against Swiss ball exercise: Start position: Supine with a Swiss ball between patient's legs and the wall. Exercise action: push against the wall for thirty seconds.~3. Supine half bridging exercise: Start position: Lying on back, knees bent Exercise action: keeping spine neutral and hinging up from the hips, move into a bridge.
Study NCT06649175 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Control Group (A): will receive the traditional physical therapy (PT) , the traditional physical therapy program will include the following:~* Stretching exercise for shortening muscle of lower limbs (LL) mainly (hip flexors, adductors, knee flexors and ankle planter flexors).~* Balance training from standing while giving perturbations.~* Balance board training.~* Step ups: repeated stepping anteriorly and laterally onto a step with both legs alternatively, progressing to higher step and decreasing upper extremity support.~* Forward and backward walking (with or without handheld mobility devices).~* Side walking (with or without handheld mobility devices).~* Walking in astride line (with or without handheld mobility devices).
Study NCT03945305 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Previous antihypertensive treatment
Description: Patients are only treated with previous antihypertensive treatment.
Study NCT05354037 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Enamel matrix derivative application for treatment of intrabony defects
Description: EMD application will be associated to M-MIST approach in control group and flapless approach in test group.
Study NCT05354037 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Enamel matrix derivative application for treatment of intrabony defects
Description: EMD application will be associated to M-MIST approach in control group and flapless approach in test group.
Study NCT04842331 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RESP301 (a nitric oxide generating solution)
Description: Administration is simple and convenient; each dose of RESP301 is administered 3 times daily (at least 4 hours apart) via inhalation using a portable handheld vibrating mesh nebuliser for approximately 8-10 minutes.
Study NCT04842331 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of Care (SOC)
Description: Participants will receive institutional SOC for the treatment.
Study NCT04842331 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care (SOC)
Description: Participants will receive institutional SOC for the treatment.
Study NCT05580874 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Massage
Description: The babies in the massage group were given a massage once a day.
Study NCT05580874 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Swaddling
Description: Control group
Study NCT06136676 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Arm 1 - Heart-Centred Spiritual Meditation: Christian contemplation
Description: Participants assigned to this condition will receive daily audio instructions of approximately 20 minutes daily over the course of 8 weeks focused on Christian contemplation delivered through a mobile app. The intervention will consist of a core contemplative practice focused on heart visualisation based on Christian tradition and prayer recitation with breathing to focus their attention on and connection to God.