AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06632405 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levocetirizine Hydrochloride
Description: 5mg daily, start 3 days before the 1st administration
Study NCT06632405 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 5mg daily, start 3 days before the 1st administration
Study NCT06634290 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intramedullary nailing augmentation
Description: Treatment of pertrochanteric hip fractures with intramedullary nailing with cephalic augmentation with bone cement
Study NCT06634290 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: intramedullary nailing
Description: Treatment of pertrochanteric hip fractures with intramedullary nailing without cephalic augmentation
Study NCT06032455 — intervention group
Intervention type: BEHAVIORAL
Intervention: Multisystemic therapy
Description: Multisystemic Therapy (MST) is an intensive, evidence-based treatment aimed at preventing out-of-home placement of adolescents with severe behavioural problems. The intervention is home-based and focuses not only on the adolescent, but also on the various systems surrounding the adolescent, such as the family, neighbourhood, school, and friends. MST helps parents increase their parenting competencies such as parental monitoring and find (more) social support in their environment. MST also helps adolescents improve their relationship with their parents, school participation, and social activities, and promotes contact with pro-social peers. These goals are achieved by working together with key figures in the family's environment. MST treatment duration is three to five months. In MST, a family can contact a therapist 24/7.
Study NCT06032455 — intervention group
Intervention type: BEHAVIORAL
Intervention: Multisystemic therapy - intellectual disabilities
Description: Multisystemic therapy - intellectual disabilities (MST-ID) is a specialisation of standard MST (see above), tailored to the needs and skill deficits of families in which the adolescent and/or parent(s) has/have a known or suspected ID. In MST-ID, among others, simplified language and visual support are used, and extra attention is paid to the generalisation of what has been learned in the treatment sessions.
Study NCT05168683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Each ALLN-346 treatment will be radiolabelled to contain 4 MBq 99mTc at time of dosing with light meal
Description: Dosing or radiolabelled ALLN-346 fast or slow release tablets or capsules. Scintigraphic images will be taken
Study NCT05168683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Each ALLN-346 treatment will be radiolabelled to contain 4 MBq 99mTc at time of dosing in fasted/fed state
Description: Selected dosing of Part One treatments in fasted and/or fed states
Study NCT06323148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: Adjuvant osimertinib for three years after radical surgery
Study NCT06323148 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: No adjuvant therapy
Description: No adjuvant therapy
Study NCT06390696 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Children in placebo arm receive an indoor sandbox containing visually similar play sand modified with peat with low microbial diversity. Families also receive an indoor cultivation set including growing box, seeds, spray bottle, plant lamp and growing medium containing peat, inorganic fertilizers, and potting gravel with low microbial diversity.
Study NCT06505018 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cureety techcare
Description: Each week, patients complete a questionnaire via the Cureety platform, specifically designed for the drug class or specific treatment being administered. Based on their responses, the Cureety TechCare algorithm classifies patients into one of four risk categories: correct (green), compromised (yellow), state to be monitored (orange), or critical state (red). (Note: the color code is not visible to the patient).~The medical team uses the dashboard for daily patient monitoring and manages alerts related to the clinical classification of the patient's condition. The physician in charge of telemonitoring interprets the data, adjusts the treatment as needed, and provides supportive care during standard care consultations. Patients are also notified of alerts with tailored messages guiding them on the actions to take according to the category determined by the device.
Study NCT06484257 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Myopia
Description: Participants in this arm would receive progressive addition lenses specifically designed to correct myopia. These lenses would typically have a prescription for correcting nearsightedness (myopia) in addition to any other vision corrections needed, such as astigmatism correction and presbyopia. The participants would wear these lenses while using computers according to the study protocol.
Study NCT06484257 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Hypermetropia
Description: Participants in this arm would receive progressive addition lenses specifically designed to correct hypermetropia. These lenses would typically have a prescription for correcting farsightedness (hypermetropia) in addition to any other vision corrections needed, such as astigmatism correction and presbyopia. The participants would wear these lenses while using computers according to the study protocol.
Study NCT05398211 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preferred Recorded Music (PRM)
Description: Preferred Recorded Music (PRM) involves a credentialed music therapist in planning and administering, which qualifies it as music therapy, which is defined as a professional use of music and its elements to improve physical, social, communicative, emotional, intellectual, and spiritual health, optimize quality of life and wellbeing(Aigen, 2013; Bruscia, 2014). PRM intervention will be delivered for 30 minutes, once per day at the same time of the day, for three consecutive days. The intervention will consist of the previously assessed preferred songs/musical pieces. During the PRM intervention the MT will start/stop the music and otherwise not engage with the participants during the listening session.
Study NCT05964530 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgery
Description: Surgery procedures include LAR+ anal preservation or APR
Study NCT05964530 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Surgery procedures include LAR+ anal preservation or APR
Study NCT05526664 — intervention group
Intervention type: OTHER
Intervention: Genetic testing and Omics analysis
Description: Blood sample for genetic analysis and for Omics analysis as metabolomics and transcriptomics
Study NCT05925452 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GenaKumab
Description: GenaKumab 3.0mg/kg dose group : GenaKumab 3.0 mg/kg, Subcutaneous injection, Q4w； GenaKumab 4.0 mg/kg dose group : GenaKumab 4.0 mg/kg, Subcutaneous injection, Q4w
Study NCT05386550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xevinapant (Debio 1143)
Description: Participants will receive 3 cycles of oral solution of Xevinapant (Debio 1143) at a dose of 200 milligrams per day (mg/day) once daily from Day 1 to 14, per 3-week cycle in combination with radiotherapy followed by 3 cycles of monotherapy of Xevinapant (Debio 1143) at a dose of 200 mg/day from Day 1 to 14, per 3-week cycle (Each cycle is of 3 weeks).
Study NCT05386550 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: IMRT
Description: Participants will receive 66 Gy of intensity modulated radiation therapy (IMRT) in 33 fractions, 2 Gy/fraction, 5 days/week.
Study NCT05386550 — intervention group
Intervention type: RADIATION
Group type: PLACEBO_COMPARATOR
Intervention: IMRT
Description: Participants will receive 66 Gy of intensity modulated radiation therapy (IMRT) in 33 fractions, 2 Gy/fraction, 5 days/week.
Study NCT05386550 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive 3 cycles of oral solution of placebo matched to Xevinapant (Debio 1143) once daily from Day 1 to 14 per 3-week cycle in combination with radiotherapy followed by 3 cycles of monotherapy of placebo matched to Xevinapant (Debio 1143) from Day 1 to 14, per 3-week cycle (Each cycle is of 3 weeks).
Study NCT05638334 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 89Zr-S095012 tracer and S095012 will be administered via an IV infusion
Description: Imaging period 1 (Part A and Part B): The tracer will be administered with S095012 at non-therapeutic mass dose. The optimal mass dose of S095012 will be investigated in part A, and used in part B.~Treatment period (Part A to C): S095012 will be administered with multiple 28 days- cycles in a Q2W schedule.~Imaging period 2 (Part C): A second tracer dose will be administered at 1st treatment dose of S095012 in part C.
Study NCT05156840 — intervention group
Intervention type: BEHAVIORAL
Intervention: Telehealth follow-up
Description: A telehealth follow-up visit will be conducted via the Epic electronic medical record with a pediatric hospitalist following hospital discharge.
Study NCT05978492 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TXN10128
Description: Participants receive TXN10128 capsules orally once daily.
Study NCT04271748 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Time Restricted Feeding
Description: The counseling on the regimen will involve instructing the subjects on study compliance and fasting times. Subjects will be instructed to choose an eight-hour eating window (e.g., 11:00am - 7:00pm) during which the patient will be able to eat his/her normal diet. During the 16-hour fasting window (e.g., 7:00pm - 11:00am), the participant will be able to drink regular water and black coffee.
Study NCT05398211 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preferred Live Music (PLM)
Description: Preferred Live Music (PLM) involves a credentialed music therapist in planning and administering which qualifies it as music therapy, which is defined as professional use of music and its elements to improve physical, social, communicative, emotional, intellectual and spiritual health, optimize quality of life and wellbeing (Aigen, 2013; Bruscia, 2014).PRM intervention will be delivered for 30 minutes, once per day at the same time of the day, for three consecutive days. The intervention will consist of the previously assessed preferred songs/musical pieces. The MT will be more actively engaged in a musical interaction with the participants in the PLM interventions.
Study NCT06023823 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Toe spread out
Description: toe-spread-out exercise.
Study NCT06023823 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dry needling+Toe spread out
Description: The group will be given 3 sessions of dry needling with Seirin branded 0.6\*50 mm acupuncture needles for trigger pointe in the abductor hallucis muscle and additionally toe-spread-out exercise.
Study NCT05931159 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abdominal Hypopressive Training
Description: Week 1 and 2 - Patient education , Hypopressive Maneuvers in Standing, Sitting and Supine 5-7 repetitions x 5 sets, with a 10-second hold each time, rest for 30 seconds between each set, 2 days/week.~Week 3 and 4, Hypopressive breathing in with varying arm movements along with Week 1 and 2 protocols.~Week 5 to 8 - Hypopressive breathing in kneeling, Four-point kneeling and sitting, and supine positions with varying arm movements 5-7 repetitions x 5 sets, with a 10-second hold each time, rest for 30 seconds between each set, 2 days/week.
Study NCT05931159 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical therapy for DrA
Description: Week 1 to 4, Draw-in maneuver in supine, Quadruped and Prone lying, Bent knee Fallouts and Curl ups. (8 to 12 repetitions x 3 sets, 2 days/week)~Week 5 to 8, Front and side planks added to week 1 to 4 exercises. (12 to 20 repetitions x e sets, 2 days/week)
Study NCT05668455 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrocortisone
Description: 1 drops 4 times a day
Study NCT05668455 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: 1 drops 4 times a day
Study NCT05051631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention plus 12 months maintenance
Description: The intervention will include 2 months of data collection in the control period, 4 months of education and awareness training, and 12 months of data collection in the maintenance time period.
Study NCT05051631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention plus 10 months maintenance
Description: The intervention will include 4 months of data collection in the control period, 4 months of education and awareness training, and 10 months of data collection in the maintenance time period.
Study NCT05051631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention plus 8 months maintenance
Description: The intervention will include 6 months of data collection in the control period, 4 months of education and awareness training, and 8 months of data collection in the maintenance time period.
Study NCT05051631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention plus 6 months maintenance
Description: The intervention will include 8 months of data collection in the control period, 4 months of education and awareness training, and 6 months of data collection in the maintenance time period.
Study NCT05051631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention plus 4 months maintenance
Description: The intervention will include 10 months of data collection in the control period, 4 months of education and awareness training, and 4 months of data collection in the maintenance time period.
Study NCT05668455 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Povidone
Description: 1 drops 4 times a day
Study NCT04752566 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Eculizumab
Description: Eculizumab will be administered via IV infusion once a week for 4 weeks.
Study NCT04752566 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered via IV infusion once a week for 4 weeks.
Study NCT06130774 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Retro walking and conventional
Description: Patient will start retro walking with first he/she will raise his/her one foot with toe off first then heel will be off from ground. swing phase of same leg would be done in backward direction with flexion on knee and extension will be performed on hip. Then patient will place the same foot on ground behind the other foot, with toe touch first on ground, and so this way patient would continue his retro-walk for 20 minutes
Study NCT06130774 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional therapy
Description: Hot pack in supine lying (10min) TENS (10min ) Tibiofemoral mobilization (grade 1,2 ,3) (10rep) Static quadriceps exercise in supine (10rep x 3sec x2set) hip abduction in side lying(10repx 2set) knee bending exercise in prone lying ( 10rep x 2set) Hamstring stretch in supine ( 10 rep x 2 set)
Study NCT06492148 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Myofascial Release
Description: The myofascial release technique is a widely used manual therapy method characterized by low-load, prolonged mechanical forces applied to manipulate the myofascial complex, aiming to restore optimal length, alleviate pain, and improve function.
Study NCT06492148 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham-Myofascial Release
Description: The hands of the researcher applying the technique will be placed in the same areas as the myofascial release technique, with only the palms in light contact for the same duration. However, no intervention will be made to create any pressure or open the tissue barrier.
Study NCT06352905 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Whole body vibration (WBV)
Description: WBV is a platform that vibrates while a person stands or sits and performs exercises. The WBV session will consist of 5 sets of 60 seconds set at 6 Hertz (frequency), 3 mm (amplitude) while performing mid-squats. There will be a 1 minute rest in between each set. These parameters were chosen as commonly used parameters in previous studies of WBV in people with PD.
Study NCT06352905 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Mid-squats performed on level ground 5 repetitions of 60 seconds with 1 minute rest in between each set.
Study NCT06375278 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intra-Ear Canal Cooling Catheter
Description: Mild therapeutic hypothermia will be applied via the catheter device installed inside the ear canal by an experienced surgeon during cochlear implantation (CI) surgery.
Study NCT05362591 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: resin bonded bridge with no preparation
Description: resin bonded bridge without enamel preparation
Study NCT05362591 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: resin bonded bridge with minimal preparation
Description: resin bonded bridge with minimal preparation of tooth enamel
Study NCT05420129 — intervention group
Intervention type: DEVICE
Intervention: MAD Therapy
Description: Participants will be treated with a Mandibular Advancement Device therapy
Study NCT05420129 — intervention group
Intervention type: DEVICE
Intervention: CPAP Therapy
Description: Participants will be treated with a Continuous Positive Airway Pressure therapy
Study NCT05148013 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pilates exercise
Description: All participants will be given a basic introduction to the Pilates-based exercises and will be taught how to activate the core muscles, which entails isometric contraction of the transverses abdominis, pelvic floor, and multifidus muscles while exhaling during diaphragmatic breathing, before beginning the exercise program. The Pilates exercise program will consist of floor exercises on a mat, including the following exercises: one-leg kick, single leg stretch, shoulder bridge, the hundred, one leg circle, and swimming. All exercises progressed at three degrees of difficulty: basic, intermediate, and advanced. Depending on the patient's tolerance, each exercise will be done for 8-10 repetitions. The treatment plan included a five-minute warm-up, twenty minutes of exercise, and a five-minute cool-down.
Study NCT05148013 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PNF exercise
Description: The PNF techniques utilized in the PNF exercise group will include a combination of isotonics, rhythmic stabilization, and repeated stretch. The exercises which will be performed are; (1) Trunk rotation in sitting position (1a) Chopping to the left and right and (1b) Lifting to the left and right, (2) Rolling activity (2a) Resistance to pelvic anterior patterns 2(b) Resistance to posterior patterns, 2(c) Combination of scapula and pelvis, 2(d) Combination of scapula and pelvis (i.e. asymmetrical exercise for trunk extension: the scapula moves in posterior elevation, the pelvis in posterior depression) and (3) Bridging activity (3a) Stabilize the pelvis in its neutral position, 3(b) Bridging lower trunk rotation and, 3(c) Bridging on two legs in the supine position.
Study NCT06514391 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: compressive single piece dental implant
Description: 4 inter-foraminal single piece compressive dental implants were placed in the mandible via flapless protocol by the aid of stereolithographic surgical guide
Study NCT05413265 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Phases 1 and 2
Description: Phase 1 participants will help inform the cultural adaptation of the study design and materials. Phase 2 will enroll 10 dyads (20 individuals) of AN/AI people who smoke and a family member. Dyad participants will help beta-test the feasibility and acceptability of the financial incentives intervention.
Study NCT06459089 — intervention group
Intervention type: BEHAVIORAL
Intervention: Selection of the parent according to children preference
Description: The children will select the parent who will accompany them during the anesthesia induction
Study NCT06459089 — intervention group
Intervention type: BEHAVIORAL
Intervention: Bringing the favorite toy of the children that will accompany the child during their perioperative period
Description: The children will bring tiheir favorite toy that will accompany them during their perioperative period
Study NCT05966363 — intervention group
Intervention type: RADIATION
Intervention: Nanodot
Description: Radiation measurements using nanodots placed on the eyes, ears, neck and lower abdomen during an imaging examination.
Study NCT05992610 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy
Description: Chemotherapy based on carboplatin 6 AUC + paclitaxel 75 mg/m2.~Radiotherapy:~D:1 - 2 x 0,5 Gy (first dose up to one hour after the end of the carboplatin infusion, second dose 3 to 6 hours later), D:2 - 2 x 0,5 Gy (interval between doses not less than 3 hours), D:8 and D:15 - 2 x 0,5 Gy (first dose up to one hour after the end of the chemotherapeutic infusion, second dose 3 to 6 hours later).
Study NCT05236010 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: rTMS
Description: Transcranial magnetic stimulation is a noninvasive form of brain stimulation in which a changing magnetic field is used to cause electric current at a specific area of the brain through electromagnetic induction. During an rTMS session, an electromagnetic coil is placed against the scalp near the forehead. The electromagnet painlessly delivers a magnetic pulse that stimulates nerve cells in the region of the brain being targeted.