AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05949996 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: A nurse-led symptom distress screening program
Description: Five implementation strategies will be conducted individually for each of the study unit at the timepoint when the study unit is being randomly allocated to the implementation condition. For each study unit, all nurses will first receive a half-day training. Each study unit under the implementation condition will receive weekly audit and feedback reports to summarize the proportion of eligible patients, proportion of eligible patients being screened, proportion of patients appropriately referred to JCICC. The senior research assistant with a nursing background will receive training and mentoring from the PI and will be the guided facilitator. The guided facilitator will conduct weekly site visits to address operational issues arise during the implementation. Lastly, while the choice of symptom assessment tool and referral criteria are standardized and cannot be modified, the routine workflow for each study unit can be adjusted according to its context and resources.
Study NCT06006325 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: electroacupuncture treatment
Description: Patients received acupuncture on both sides of the Zusanli (ST36) acupuncture points, and after Deqi , the needle was connected to an electro-acupuncture device (Hwato, Suzhou Medical ). The EA stimulation lasted for 30 min.
Study NCT06006325 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham electroacupuncture treatment
Description: The participants in the SHAM-EA group performed shallow punctures at the bilateral non-acupuncture points, did not perform the Deqi operation, and were connected to the electroacupuncture stimulator but not energized.
Study NCT05009160 — intervention group
Intervention type: DEVICE
Intervention: dreaMS App R2.1
Description: The Healios+Me platform App which contains the dreaMS App will be downloaded by all participants and all participants (PwMS and HC) will follow the same schedule
Study NCT03049787 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Exercise Protocol
Description: Home exercise therapy protocol given to patient to be completed at home.
Study NCT03049787 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical Therapy Protocol
Description: Formal physical therapy protocol to be given to physical therapist working with patient to direct formal intervention along with a home therapy protocol.
Study NCT04583891 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: IntelliCare
Description: IntelliCare is a self-guided, fully automated suite of 6 apps designed for brief, frequent check-ins to promote skill acquisition. IntelliCare has been shown in both general deployment and human-supported trials to be efficacious in reducing symptoms of depression and anxiety.
Study NCT04583891 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducation
Description: The Patient Education app will contain content relevant for general distress management. This includes information about thoughts/worries, prevalence of mood symptoms, CBT strategies for coping with negative affect, and other information typical of education-based mental health apps. The structure of this app will closely mirror patient education websites and apps which mimic the form and structure of apps that target cancer survivors and that primarily provide educational information about cancer and related symptoms.
Study NCT04583891 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Coaching
Description: The randomization of added coaching vs. no added coaching after 1 week will only be carried out in the IntelliCare group. Coaching is a human supported approach to optimizing the use and benefit of the IntelliCare apps.
Study NCT05085665 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivermectin
Description: single dose, 150 ug/kg
Study NCT00528255 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Misoprostol Vaginal Insert (MVI 100)
Description: The MVI 100 is misoprostol 100 mcg, formulated in a sustained release, nonbiodegradeable hydrogel polymer, with a polyester knit retrieval tape; IV oxytocin is permitted ad lib 30 minutes following removal of the MVI assuming no contraindications.
Study NCT06360809 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prehabilitation exercise program
Description: After the allocation, the intervention will consist of a prehabilitation program lasting 4 weeks. Each week, there will be three sessions, with one being face-to-face and the other two being unsupervised sessions but with online video-support. Face-to-face sessions will be organized in small groups, and each patient of the PEP group will have an individualized plan based on data obtained during the initial assessment. Each session will include a combination of strength training and moderate aerobic training in a circuit format with movements especially involving the upper body.
Study NCT04423913 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Administration of embolization beads
Description: Patients will receive embolization beads, loaded with doxorubicin or not.
Study NCT05781568 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biomarker dosage
Description: The simultaneous dosage of the 3 serum biomarkers will be performed at the Clinical Pathology Laboratory, using the instrument: µTASWakoTM i30 (Micro Total Analysis System) - Fujifilm.
Study NCT05339321 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: SCG101
Description: SCG101 is an autologous HBV-specific T cell receptor engineered T cell therapy.
Study NCT05339321 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: PD1/PD-L1 checkpoint inhibitor
Description: Commercially approved for HCC treatment.
Study NCT05453019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cochlear Implant
Description: The surgeon will make a small cut (incision) behind patient's ear, and form a small hole in the portion of skull bone (mastoid) where the internal device rests. Then the surgeon create a small opening in the cochlea in order to thread the electrode of the internal cochlear implant device. The skin incision is stitched closed so that the internal device is under the skin.
Study NCT05453019 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cochlear Implant
Description: The surgeon will make a small cut (incision) behind patient's ear, and form a small hole in the portion of skull bone (mastoid) where the internal device rests. Then the surgeon create a small opening in the cochlea in order to thread the electrode of the internal cochlear implant device. The skin incision is stitched closed so that the internal device is under the skin.
Study NCT04817891 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HD-tDCS
Description: Participants will receive HD-tDCS at up to 4 mA per channel for 20 minutes for 10 sessions. Dose determined through individualized computational models.
Study NCT04257383 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sugira Muryango
Description: Strong Families, Thriving Children Sugira Muryango is a home-visiting intervention that empowers low-income families enrolled in Rwanda's social protection system to support early childhood development and healthy family functioning.
Study NCT04268043 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: flexible laryngeal airway mask
Description: Ventilation with flexible laryngeal mask airway
Study NCT04268043 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: proseal laryngeal mask airway
Description: Ventilation with proseal laryngeal mask airway
Study NCT05803616 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Liquid biopsy
Description: ctDNA measured in the plasma and analyse by next generation sequencing (NGS) for minimal residual disease (MRD)
Study NCT04939662 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Olaparib+Bevacizumab to SCLC patients
Description: Olaparib 300 mg bid per os every 12 hours D1-21 administered in each cycle days. One cycle consists of 21 days.~Bevacizumab 15 mg/kg via IV administered on Day1 of each cycle. One cycle is consisted of 21 days.~The subject's body weight criterion is based on C1D1 (first dose date), and if more than 10% of BW is increased and decreased, the drug dose is changed to that BW.
Study NCT05026710 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Silicone (Coloplast Imajin Hydro) ureteral stent
Description: During the end of the standard of care ureteroscopy the silicone stent will be placed.
Study NCT05026710 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-silicone (Polyurethane/Percuflex) ureteral stent (any manufacturer)
Description: During the end of the standard of care ureteroscopy the Non-silicone (Polyurethane/Percuflex) stent will be placed.
Study NCT06232928 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Early Class II elastics
Description: Participants were treated by a fixed orthodontic appliance with intermaxillary class II elastics to correct the class II malocclusion. patients were instructed to wear immediate light short Class II elastics from upper canines to lower second premolars for 24 hours except while eating and change the elastics every 12 hours.
Study NCT06232928 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Class II elastics
Description: patients were treated by a fixed orthodontic appliance with intermaxillary Class II elastics. patients were instructed to wear Class II elastics from upper canines to lower first molars for 24 hours except while eating and change the elastics every 12 hours after reaching to rigid stainless steel arch wires.
Study NCT06198842 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treosulfan
Description: Treosulfan 21mg/m2 (days -6, -5, -4)
Study NCT06252233 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: patient- and physician-centered QoL monitoring
Description: Electronic QoL monitoring including QoL diagnosis and therapy (pain therapy, psychotherapy, social support, nutrition, physiotherapy, fitness, respiratory counselling, palliative care). Patients and treating physicians have access to the results of their QoL monitoring and to a network of local healthcare providers.
Study NCT06252233 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Electronic QoL monitoring without QoL diagnosis and therapy. Patients and treating physicians have no access to the results of their QoL monitoring. The therapist network is also available for control arm.
Study NCT04943003 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Direct Current Stimulation (tDCS)
Description: Initially, a measuring tape will be used to make the markings and measurements necessary for placing the electrodes.~Regarding neurostimulation, the tDCS device is simple and portable, consisting of four main components: two electrodes (anode and cathode), an ammeter (electric current intensity meter), a potentiometer (voltage controller between electrodes) and a set of batteries. We will use the TCT-Research Neurostimulator, developed by Trans Cranial Technologies (Hong Kong, China), Regarding the protocols, the Active tDCS group will receive active tDCS for 30 minutes and for 5 consecutive days, in two weeks, with an anode positioned on the left DLPFC and a cathode electrode placed on the right supraorbital area. The 10-20 International EEG system will be taken as a reference. The current intensity will be defined from computational modeling, using Nuclear Magnetic Resonance (NMR) to estimate and individualize the dose to be administered.
Study NCT04943003 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Transcranial Direct Current Stimulation (tDCS)
Description: Initially, a measuring tape will be used to make the markings and measurements necessary for placing the electrodes.~Regarding neurostimulation, the tDCS device is simple and portable, consisting of four main components: two electrodes (anode and cathode), an ammeter (electric current intensity meter), a potentiometer (voltage controller between electrodes) and a set of batteries. We will use the TCT-Research Neurostimulator, developed by Trans Cranial Technologies (Hong Kong, China), Regarding the protocols, the Active tDCS group will receive active tDCS for 30 minutes and for 5 consecutive days, in two weeks, with an anode positioned on the left DLPFC and a cathode electrode placed on the right supraorbital area. The 10-20 International EEG system will be taken as a reference. The current intensity will be defined from computational modeling, using Nuclear Magnetic Resonance (NMR) to estimate and individualize the dose to be administered.
Study NCT04853355 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Spironolactone 50 mg
Description: Add Spironolactone 50 mg to previous regimen
Study NCT05614973 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional method
Description: The conventional method utilizes a 18G biopsy gun to acquire three or more tissue cores with the corresponding number of liver capsule punctures. Plugging of the biopsy needle track is not performed.
Study NCT05614973 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coaxial method with needle-track plugging
Description: The coaxial method utilizes a 17G coaxial needle with 18G biopsy gun to acquire three or more tissue cores with a single liver capsule puncture. Biopsy needle track is plugged using a slurry of gelatin particles (EGgel S Plus 2000-4000 μm).
Study NCT06495385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Evolution of renal function
Description: Plasma creatinine levels and glomerular filtration rate estimated using the CKD-Epi formula adjusted for 1.73 m2 body surface area will be measured.
Study NCT06495385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of haemoglobin levels
Description: Haemoglobin levels will be measured.
Study NCT06495385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Measurement of biological parameters
Description: Plasma levels of urea, calcium, phosphorus and parathyroid hormone, as well as alkaline reserve, will be measured.
Study NCT06495385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Measure sodium and protein consumption
Description: 24-hour urine volume, proteinuria, urea and sodium, will be measured.
Study NCT06495385 — intervention group
Intervention type: BEHAVIORAL
Intervention: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)
Description: The descriptive system comprises five dimensions: mobility, personal care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, mild problems, moderate problems, severe problems and extreme problems. The figures for the five dimensions can be combined into a 5-digit number describing the patient's state of health. Scores close to 1 indicate the best health you can imagine and those close to 0 the worst health you can imagine.
Study NCT05203523 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial alternative current stimulation (tACS)
Description: A light electrical current will be applied to the scalp of the participants via 2 electrodes, while the participants performs cognitive exercises with the guidance of a trained research assistant.
Study NCT05203523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cognitive exercises
Description: Participant will perform memory and learning games/tasks through Mind Triggers app on an IPad. Participants will be guided by a highly trained research assistant.
Study NCT05203523 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: cognitive exercises
Description: Participant will perform memory and learning games/tasks through Mind Triggers app on an IPad. Participants will be guided by a highly trained research assistant.
Study NCT01400789 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Insulin Lispro
Description: Dosage form- Subcutaneous Injection
Study NCT01400789 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Insulin Lispro
Description: Dosage form- Subcutaneous Injection
Study NCT04423861 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitazoxanide
Description: Patients will receive nitazoxanide 600 mg BID for 7 days.
Study NCT04423861 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive matching placebo BID for 7 days.
Study NCT05496751 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low amount, low intensity exercise
Description: Participants will exercise under supervision. Exercise dose will vary by amount and intensity
Study NCT05496751 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low amount, high intensity exercise
Description: Participants will exercise under supervision. Exercise dose will vary by amount and intensity
Study NCT05496751 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High amount, high intensity exercise
Description: Participants will exercise under supervision. Exercise dose will vary by amount and intensity
Study NCT04665167 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Body image exposure
Description: Exposure therapy is a key element of evidence-based cognitive behaviour therapy for eating disorders . Body image exposure intervention involves deliberate, planned, and systematic exposure to the body image. Participants will be asked to stand so that they can see their whole body - far enough back. Participants will be asked to look at their bodies on screen. Participants will be continually encouraged by the facilitator for looking at and talking about the body parts.
Study NCT04665167 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Self-compassion
Description: The self-compassion intervention condition consists of Neff's self-compassion exercises. These exercises are part of the self-compassion intervention condition. Meditation text used in this study is obtained from the following link https://self-compassion.org/category/exercises/.
Study NCT05745454 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HER2-E-CART cells
Description: E-CAR-T is a novel second-generation CAR-T product targeting HER2 protein
Study NCT05452590 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided wire-in-needle technique for central venous catheter placement
Description: The guidewire will be connected to the needle. The IJV will be punctured in a long-axis in-plane approach. When the needle tip enters the IJV, the guidewire will be advanced through the needle into the IJV under continuous ultrasound visualization. The needle will then be removed. The correct guidewire position in the IJV will be confirmed in the long-axis and short-axis view. Afterwards, the second guidewire will be placed in the same IJV approximately 1-2 centimeters distal to the fist guidewire using the same technique. The correct guidewire position in the IJV will be confirmed in the long-axis and short-axis view again.
Study NCT05355025 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WiserAD
Description: See Arms
Study NCT05355025 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Attention control
Description: See Arms
Study NCT05459285 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 14028 injection
Description: 14028 injection, single dose, s.c. injection
Study NCT05459285 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: dulaglutide injection
Description: dulaglutide injection(TRULICITY®), single dose, s.c. injection
Study NCT05583201 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: KD-496
Description: Autologous genetically modified anti-NKG2DL/CLDN18.2 CAR transduced T cells
Study NCT04775251 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Upward rotation exercise
Description: Treatment for correction of depressed scapular Alignment by exercise ( Upward Rotation Exercises) for 6 weeks.
Study NCT04575103 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antipsychotic
Description: Antipsychotic treatment >0.5 DDD
Study NCT04915651 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gallbladder Cryoablation
Description: Percutaneous cryoablation of the gallbladder.
Study NCT05922020 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen gas
Description: Administration of Oxygen by inhalation
Study NCT05922020 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oxygen gas
Description: Administration of Oxygen by inhalation
Study NCT06147570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10365 capsules
Description: HS-10365 will be administered orally twice daily until the occurrence of disease progression, unacceptable adverse events, withdrawal of consent, death or the end of the study.
Study NCT05112627 — intervention group
Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo blood collection
Study NCT05183048 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [89Zr]Panitumumab Tracer
Description: All patients entered into the study will have \[89Zr\]Panitumumab-PET/MRI imaging.
Study NCT05555251 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI-1607
Description: administered at different doses in Phase I by intravenous infusions every 3 weeks.
Study NCT05555251 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI-1607
Description: administered at the recommended dose in Phase 2a by intravenous infusions every 3 weeks.
Study NCT05555251 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: administered at 8mg/kg for the first infusion and at 6mg/kg in subsequent infusions by intravenous infusions every 3 weeks.
Study NCT05533775 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Obinutuzumab
Description: Participants will receive intravenous (IV) obinutuzumab pretreatment on Days 1 and 2 of Cycle 1 (Cycle length = 21 days)