AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04846478 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tazemetostat
Description: orally as a tablet twice daily.
Study NCT05667402 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TBF regimen
Description: The subjects receive TBF conditioning regimen (Thiotepa, Busulfan, Fludarabine) before allo-HSCT.
Study NCT05667402 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: modified BuCY2 regimen
Description: The subjects receive modified BuCY2 conditioning regimen (Busulfan, Cytarabine, ATG, Cyclophosphamide, CCNU) before allo-HSCT.
Study NCT06493838 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
Description: Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
Study NCT05062369 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: TaskFlow Transcranial Electrical Stimulation device
Description: The TaskFlow Transcranial Electrical Stimulation device (TaskFlow-TES) is a custom brain stimulation device developed in-house at the University of Minnesota. Each tDCS intervention will last 20 minutes of either (i) 10 active (2-mA) or (ii) 5 active and 5 sham transcranial direct current stimulation (tDCS) over the course of 10 treatment sessions.
Study NCT05062369 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TaskFlow Transcranial Electrical Stimulation device
Description: The TaskFlow Transcranial Electrical Stimulation device (TaskFlow-TES) is a custom brain stimulation device developed in-house at the University of Minnesota. Each tDCS intervention will last 20 minutes of either (i) 10 active (2-mA) or (ii) 5 active and 5 sham transcranial direct current stimulation (tDCS) over the course of 10 treatment sessions.
Study NCT05062369 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Executive Function Focused Cognitive Training
Description: Working memory focused training occurs on a computer and consists of a variety of exercises selected to (i) place demands on the executive and storage functions of working memory (ii) adapt to challenge the participant's current ability level, (iii) provide ongoing feedback, and (iv) present novel stimuli across verbal, visual and spatial modalities. Training tasks are developed in-house. Tasks for each participant are delivered from and responses, audio, and video are stored on the HST server. The aim of using multiple tasks that require executive functions is to engage brain network functional connectivity in a number of different ways to promote generalization. Investigators will monitor each participant's training and customize the intervention to balance challenge and engagement. In addition, pre- and post-intervention, participants will perform 4-minute versions of a word and a spatial 3-back task identical across all weeks (but differing from the assessment versions).
Study NCT05062369 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Executive Function Focused Cognitive Training
Description: Working memory focused training occurs on a computer and consists of a variety of exercises selected to (i) place demands on the executive and storage functions of working memory (ii) adapt to challenge the participant's current ability level, (iii) provide ongoing feedback, and (iv) present novel stimuli across verbal, visual and spatial modalities. Training tasks are developed in-house. Tasks for each participant are delivered from and responses, audio, and video are stored on the HST server. The aim of using multiple tasks that require executive functions is to engage brain network functional connectivity in a number of different ways to promote generalization. Investigators will monitor each participant's training and customize the intervention to balance challenge and engagement. In addition, pre- and post-intervention, participants will perform 4-minute versions of a word and a spatial 3-back task identical across all weeks (but differing from the assessment versions).
Study NCT05521282 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Treatment group
Description: Based on the basic treatment, Qianglidingxuan Tablets were given 6 tablets/time, 3 times a day, and warm water was given for 12 weeks.
Study NCT05521282 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Treatment group
Description: Based on the basic treatment, Qianglidingxuan Tablets were given 6 tablets/time, 3 times a day, and warm water was given for 12 weeks.
Study NCT05882331 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Extracorporeal photopheresis
Description: ECP is initiated on study inclusion day by Therakos Cellex system, according to manufacturers' instructions. Each patient receives two ECP cycles for 2 weeks, each consisting of two sessions on consecutive days per week (alltogether four sessions), through a peripheral or central venous route. Cycles 1 and 2 are separated by 5 consecutive days. One ECP session takes \~3 hours, and is separated into 4 phases. On priming, the system performes a series of calibrations to ensure proper operation. During collection, 1500 ml of whole blood is processed to collect a concentrated buffy coat containing white blood cells, while other cells and plasma are reinfused. During the photoactive phase, a prescribed dose of 8-methoxypsoralen is added to the buffy coat, which is then circulated through ultraviolet-A photoactivation. During reinfusion phase, treated cells are automatically reinfused to the patient.
Study NCT04891861 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Apixaban
Description: Direct Oral Anticoagulation all at label dose and frequency
Study NCT06012695 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NBM-BMX Capsule
Description: Each capsule contains 100 mg of the active ingredient.
Study NCT06012695 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: TMZ will be administered orally at a 75 mg/m2 dose daily during concomitant therapy. In the maintenance period, days 1-5 of each cycle will be administered 150-200 mg/m2.
Study NCT06012695 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Standard radiotherapy
Description: A total dose of 60 Gy will be administered in 6 weeks.
Study NCT04776876 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Retifanlimab
Description: Given IV
Study NCT04776876 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telotristat Ethyl
Description: Given PO
Study NCT05249764 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Supervised Home Based Exercise Training
Description: Exercise program was prepared based on WHO, American College of Sports Medicine (ACSM), Geriatrics Physiotherapists Association and Otago exercise program for the exercise group. The older adults are given individual supervised exercise training in their own homes for eight weeks, 3 days a week and 45 minutes a day, by a physiotherapist according to social distance rules. This exercise training consists of a program that includes strengthening, flexibility, aerobic and balance exercises. Each exercise is started with eight repetitions and each week will be increased by two repetitions. In case of fatigue, a rest is given. Brochures are also be prepared for the exercises. Before each session, individuals performed warm-up exercises for 5 minutes. At the end of the session, individuals performed cooling exercises.
Study NCT05249764 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Unsupervised stretching and breathing exercises
Description: Individuals in the control group are performing stretching exercises for proximal extremity muscles for 15 minutes 3 times a week for eight weeks. The participants also perform breathing exercises for 5 minutes a day.
Study NCT06529601 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CAD/CAM mandibular fixed retainer
Description: Keeppy is a Class IIa custom-made medical device manufactured by Digital Service Leone s.r.l. - via Pratese 160/b, Florence, Italy. The Keeppy is an individualized fixed retainer, made of a Nickel-free Chrome Cobalt alloy, produced with a CAD-CAM procedure starting from a digital impression made with an intraoral optical scanner (3 Shape), which allows a perfect adaptation to the lingual surfaces of the 6 lower anterior teeth on which it is bonded. The device is characterized by the presence of applicators that can be placed temporarily on the buccal surface of the canines, which facilitate the clinician in the precise application of the device and which are removed as soon as the bonding phase of the retainer is complete. Bonding is performed using classic composite resins following a preparation phase of the lingual surface of the tooth consisting of the application of etchant (37% orthophosphoric acid) for 30 seconds and adhesive (primer-bonding).
Study NCT06529601 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional mandibular fixed retainer
Description: The standard control device, which is among the most commonly used in routine clinical practice, consists of a steel braided wire. The device selected for the Class IIa investigation is the Ortho Flex Tech manufactured by Reliance Orthodontic Products, Inc. 1540 West Thorndale Ave. Itasca, IL 60143 USA. The Ortho Flex Tech steel braided wire is manually shaped by the clinician and cut with a wire cutter so that it has the proper length to extend over the 6 dental elements. Once the correct length has been defined, it is then held in place on the lingual surface of the teeth by the use of 2 interdental wires passing doubly through the interdental area (between the lateral incisor and canine on one side and the other). This allows the device to be bonded using composite resin after etching the lingual surfaces of the lower anterior teeth.
Study NCT06403033 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mini-implant-supported Twin-Block
Description: Mini-implants will support the Twin-Block appliance during the functional treatment.
Study NCT06403033 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Twin-Block
Description: This is the main appliance that will be used to correct the Class II deformity.
Study NCT06465121 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: peripheral intravenous catheterization performed with ultrasound guidance by a trained nurse
Description: Intravenous catheterization using ultrasound-guidance to allow real-time visualization of target veins in pediatric patients with difficult intravenous access
Study NCT06329336 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Emotional Competence for Children and Parents
Description: This preventive parenting intervention combines behavioral parenting and mindfulness-based well-being practices to support effective parenting.
Study NCT04964401 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thoracic paravertebral block vs Erector spinae plane block
Description: Thoracic paravertebral block and erector spinae plane block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, when the patient is placed in the lateral decubitus position.
Study NCT04334811 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Stereotactic ablative radiotherapy
Description: Stereotactic ablative radiotherapy (SAbR) delivers of a potent, ablative or nearly ablative dose of radiation in oligofractions (ie, five or fewer fractions) primarily to create a compact dose delivered accurately to the intended target with steep gradients in all directions (geometric avoidance) and avoid damaging normal tissues.
Study NCT05661201 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NEROFE
Description: weekly doses of NEROFE (48-288 mg/m2) (dose level 1: 96 mg/m2, dose level -1: 48 mg/m2, dose level 2: 192 mg/m2, dose level 3: 288 mg/m2), intravenously over 60 minutes
Study NCT05173792 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK119
Description: Subjects will receive AK119 intravenously.
Study NCT06507176 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: flexible ureteroscopic lithotripsy
Description: This group of patients underwent flexible ureteroscopic lithotripsy.
Study NCT06507176 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: percutaneous nephrolithotomy
Description: This group of patients underwent percutaneous nephrolithotomy.
Study NCT05661201 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: weekly doses of 8 mg/m2 (fixed dose), intravenous push over 3 mins;
Study NCT05543434 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hyaluronic acid
Description: anti-inflammatory, anti-edematous, osseoinductive.
Study NCT05543434 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic acid
Description: anti-inflammatory, anti-edematous, osseoinductive.
Study NCT06291961 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: CS-101 injection
Description: Autologous CD34+ hematopoietic stem cell suspension modified by in vitro base editing technique
Study NCT06190665 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DEB-TACE with visualable microspheres
Description: Drug-eluting Beads Transcatheter Arterial Chemoembolization(DEB-TACE) with visualable microspheres
Study NCT06190665 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: DEB-TACE with PVA microspheres
Description: Drug-eluting Beads Transcatheter Arterial Chemoembolization(DEB-TACE) with polyvinyl alcohol microspheres
Study NCT04887038 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SRT-015
Description: Each study part (A,B and C) will be completed sequentially, but with partial overlapping. The first cohort of Part B (Cohort B1) may be initiated after safety, tolerability and available PK data are assessed and deemed suitable to continue for a single dose on Part A that is equal to or greater than the total exposure of cohort B1. Part C (Cohort C1 \& C2) may be initiated after safety, tolerability and PK data are assessed and deemed suitable to continue for a single dose in part A that is at least double the specified dose from part C.
Study NCT04887038 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo for SRT-015
Description: Matching Placebo
Study NCT06236581 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: GEM Intervention
Description: Lifestyle coaching
Study NCT06009497 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Romiplostim
Description: Romiplostim 10 µg/kg, subcutaneous injection, once a week.
Study NCT06009497 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciclosporin
Description: Ciclosporin 3-5mg/kg/d, adjust the dose to keep trough ciclosporin plasma concentration 100-200ng/ml.
Study NCT05020119 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoantigen-expanded cell therapy.
Description: Infusion of personalized neoantigen-expanded T (CIK) cells
Study NCT05753969 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MT1 Device
Description: Pre-and post-evaluation in MT1 device following stimulant treatment or placebo control
Study NCT05753969 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: MT1 Device
Description: Pre-and post-evaluation in MT1 device following stimulant treatment or placebo control
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Stream Dx
Description: home uroflowmetry device
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Stream Dx
Description: home uroflowmetry device
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DFree
Description: at home wearable bladder scanner
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: DFree
Description: at home wearable bladder scanner
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TestCard
Description: mobile urinalysis reader
Study NCT05508165 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: TestCard
Description: mobile urinalysis reader
Study NCT05529173 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Povidone-Iodine 10%
Description: Nasal swab stick application of Povidone-Iodine 10% prior to surgery
Study NCT05529173 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% NaCl Solution
Description: Nasal swab stick application of 0.9% NaCl Solution prior to surgery
Study NCT04865978 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apixaban
Description: Patients randomized to apixaban will be started on a dose of 5 mg BID.
Study NCT04865978 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Warfarin
Description: Patients randomized to warfarin will be started on a dose per institutional protocol and titrated to an INR goal of 2.0 - 2.5.
Study NCT04865978 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: LVAD implant
Description: Subjects will undergo HeartMate 3 LVAD implant prior to randomization
Study NCT04865978 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LVAD implant
Description: Subjects will undergo HeartMate 3 LVAD implant prior to randomization
Study NCT06101862 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CCTA
Description: Participants will be examined with CCTA during admission.
Study NCT06101862 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Conventional ICA
Description: Patients will be examined with conventional standard-of-care ICA.
Study NCT06101862 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Team-based interventional triage
Description: The CCTA will be discussed at a coronary CT-team conference to establish the treatment strategy and provide guidance for any necessary interventional procedure.
Study NCT06232421 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Foscelantan
Description: Foscelantan, medicinal plate 4.0x5.0 cm in package No. 1 produced by UNITEHPROM BSU, Republic of Belarus
Study NCT06232421 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Povidon-iodine
Description: Povidone-iodine solution 100 mg/ml produced by BelAseptika CJSC, Republic of Belarus
Study NCT06225531 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Autobiographical Memory Based Intervention
Description: The intervention involves 6 sessions of therapeutic input based around autobiographical memories. Memory based activities will broadly follow the 5 stages outlines in the broad-minded affective coping (BMAC) procedure, but with a focus on specific memories. It will follow the following structure:~Session 1 - Introduction and Familiarisation Session 2 - Neutral Memories Session 3 - Positive Memories Session 4 - Memories of Moves Away from Suicidality Session 5 - Practice of Preferred Memory (from Sessions 2-4) Session 6 - Continued Practice and Post-Intervention Planning
Study NCT05877287 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mindfulness-based stress reduction program
Description: The FTSA program will be carried out once a week for 60 minutes, for 8 weeks, in a total of 8 sessions. The program will be conducted in face-to-face groups. Sessions will be held in a suitable area in the practice area. In each 60-minute session, it is planned to be 20 minutes of narration on the subject of the session, accompanied by a power point presentation, and the remaining 40 minutes of exercise, meditation practices and sharing experiences.
Study NCT06478771 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Essix retainer
Description: A clear plastic removable retainer.
Study NCT06478771 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Essix retainer
Description: A clear plastic removable retainer.
Study NCT05712889 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VIP236 (Q3W)
Description: VIP236 will be administered by IV infusion once every 3 weeks, for a 21-day cycle.
Study NCT05712889 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VIP236 (Q2W)
Description: VIP236 will be administered by IV infusion once every 2 weeks, for a 28-day cycle.
Study NCT06431646 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: A web-based education intervention developed for university students with PMS
Description: The web-based education program includes the definition, prevalence, importance, causes, symptoms, diagnosis, risk factors, management strategies and treatment options of PMS. The education emphasizes non-pharmacological strategies for managing PMS, including diet, exercise and body mass index (BMI), sleep hygiene, smoking cessation, stress management, as well as vitamin and mineral supplements, herbal therapy, acupuncture, acupressure and reflexology.
Study NCT06077071 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: ViewRay MRIdian Stereotactic Radiosurgery
Description: Participants will undergo stereotactic radiosurgery of the spinal cord on the ViewRay MRIdian, a hybrid MRI-linac platform, with 40 Gy in 5 fractions prescribed to the planning target volume (PTV).
Study NCT06077747 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Coil Embolization of the Lumbar Vein
Description: Catheter based venography will first confirm Nutcracker physiology with retrograde lumbar vein flow and epidural venous plexus congestion. The lumbar vein will then be coil embolized.
Study NCT06478771 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Lingual retainer
Description: A fixed retainer placed on the lingual side of the teeth.
Study NCT04181463 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isopropyl Alcohol
Description: Given via nasal inhalation
Study NCT04181463 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Given via nasal inhalation