AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05089253 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dry Needling
Description: The subject will be in the supine position and receive dry needling. The first point will be at the medial femoral condyle of the knee joint line in vastus medialis muscles. The second point will be at the lateral femoral condyle of the knee joint line in vastus lateralis muscles. The third point will be above the base of the patella in the rectus femoris muscle. The fourth point will be 2cm above the third point in rectus femoris muscles. These four points were the most common places of trigger point at quadriceps muscles. Dry needling is affected on A-delta fibers. Therefore when superficial dry needling with a noxious stimulation leads to stimulation on A-delta fibers, the excitation remains almost 72 hours and gradually decreases.~The standard 9- point dry needling technique will be applied for 20 minutes per session 3 times a week for 4 weeks.
Study NCT06228976 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based, smoking cessation focused text messages.
Description: Participants will receive mindfulness-based, smoking cessation focused text messages everyday for 12 weeks.
Study NCT05089253 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Kinesio tapping
Description: The subject will be in the supine position and receive Kinesio taping. The Kinesio tape application with no tension one Y strip with a length of 20 cm, an anchor of 2 cm.~The Kinesio tape will be applied to the participants in supine with the knee in 90 flexions. Two Y-shaped tapes are applied above and below the patella. The tape will be removed after 48 hours after application. The Kinesio tape will be applied 3 times a week for 4 weeks.
Study NCT06439459 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stromal vascular fraction transplantation
Description: Stromal vascular fraction was extracted from subcutaneous fat harvested from either the abdomen or the posterior inner thigh region. The SVF cell-pellet was washed and was adjusted to 2×10\^6 cells/mL. The skin was marked with methylene blue and a total of 0.5ml (around 1×10\^6 cells) were transplanted intradermally at the center of each 2cm×2cm squares.~The expander was inflated two times a week using constant pressure inflation method, where the intracapsular pressure was monitored using a pressure meter and the inflation was halted when the pressure reached 100 mmHg. This procedure was repeated until adequate skin area was achieved for subsequent facial restoration surgery.
Study NCT06228976 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational messages
Description: Text messages focus on the health risks of smoking and secondhand smoking, once everyday for 12 weeks.
Study NCT06228976 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control messages
Description: Text messages focus on the general healthy lifestyle, once everyday for 12 weeks.
Study NCT04612933 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention group video consultations
Description: All appointments, scheduled and non-scheduled are by telemedicine using video to commutate with the health care professionals.~Patients will follow their usual treatment.
Study NCT05578131 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: high flow nasal oxygen
Description: In the intervention group, pre-oxygenation was provided using HFNO via Optiflow THRIVE™ (Fisher and Paykel Healthcare Limited, Auckland, New Zealand) until SpO2 on pulse oximetry was > 95% and for at least 3 min. A flow of 0.5 l/kg/min-1 was used until induction agents had been administered, and then increased to 2 l/kg/min-1. Nasal oxygenation was continued without ventilation of the lungs while waiting for neuromuscular blockade, and during placing, replacing or repositioning the airway. Anaesthetists were free to carry out bag-mask ventilation of the lungs if they considered this necessary to maintain safe oxygen saturations. After securing the airway, the patient was connected to a circle circuit primed with 100% oxygen and the FIO2 was continued at 100% for a period of at least five more minutes. Relevant times were recorded, including start of pre-oxygenation and start of induction of anaesthesia.
Study NCT05578131 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: face mask
Description: In the control group, pre-oxygenation was provided using 100% oxygen via a sealed facemask and a circle-absorber anaesthetic circuit primed with 100% oxygen by installing a ventilation bag to the mouthpiece filter and ventilating the circuit with 100% oxygen. Anaesthetists were free to carry out bag-mask ventilation of the lungs once induction medications had been administered.
Study NCT06424405 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: titration procedure for MAD treatment
Description: The OSAHS patients referred for MAD treatment will experience either the objective titration procedure or the subjective titration procedure.
Study NCT06424405 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: titration procedure for MAD treatment
Description: The OSAHS patients referred for MAD treatment will experience either the objective titration procedure or the subjective titration procedure.
Study NCT05381415 — intervention group
Intervention type: OTHER
Intervention: Inhalation of bronchodilation therapy at FRC
Description: the patient will be asked to inhale the bronchodilator (salbutamol pMDI, 400 µg) with a spacer from FRC (functional residual capacity, in a random order, with the assistance of an operator. The spacer will be connected to a Fleish flowmeter placed in series with the pMDI device.~The valve included in the spacer will guarantee that only the air inhaled by the patient will pass through the flowmeter, reducing the risk of contamination. In both cases a low inspiratory flux and a period of apnea after inhalation of 10 seconds will be used. Before and after the administration it will be asked to the patient to execute a spirometry, a plethysmography, a lung diffusion test, and the NEP technique. These will allow the characterization of the bronchodilator effect in terms of static and dynamic volumes, heterogeneity of ventilation distribution and volume of closure, expiration flux-limitation.
Study NCT05381415 — intervention group
Intervention type: OTHER
Intervention: Inhalation of bronchodilation therapy at RV
Description: the patient will be asked to inhale the bronchodilator (salbutamol pMDI, 400 µg) with a spacer from VR , with the assistance of an operator. The spacer will be connected to a Fleish flowmeter placed in series with the pMDI device.~The valve included in the spacer will guarantee that only the air inhaled by the patient will pass through the flowmeter, reducing the risk of contamination. In both cases a low inspiratory flux and a period of apnea after inhalation of 10 seconds will be used. Before and after the administration it will be asked to the patient to execute a spirometry, a plethysmography, a lung diffusion test, and the NEP technique. These will allow the characterization of the bronchodilator effect in terms of static and dynamic volumes, heterogeneity of ventilation distribution and volume of closure, expiration flux-limitation.
Study NCT05573880 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Galileo Med35
Description: whole-body vibration training on the platform
Study NCT04757662 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tadalafil
Description: Tadalafil is commercially available and will be purchased by the Siteman Cancer Center and distributed to participants free of charge.
Study NCT06452498 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin Hydrochloride
Description: Metformin Hydrochloride encapsulated immediate-release tablet of 500 mg, backfilled with cellulose.
Study NCT06452498 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Capsule filled with cellulose.
Study NCT05660759 — intervention group
Intervention type: PROCEDURE
Intervention: Portal vein embolization
Description: Portal vein emboliazation with either NBCA or micro particles.
Study NCT06397326 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Return to work coordinator + PRATICAdr 2.0
Description: The Return to work coordinator (RTW-C) uses PRATICAdr. 2.0 (web application).
Study NCT06397326 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Return to work coordinator only
Description: The Return to work coordinator (RTW-C) intervenes on employees on sick leave as usual
Study NCT04887064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: Sotorasib will be administered as an oral tablet.
Study NCT04732598 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel + bevacizumab therapy
Description: The following regimen will be continued as a 28-day course until disease progression or the criteria for treatment discontinuation are met.~\[Paclitaxel\] 90mg/m\^2, day1,8,15, IV \[Bevacizumab\] 10mg/kg, day1,15, IV
Study NCT04996030 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SY-2101
Description: SY-2101 will be administered per dose and schedule specified in arm description.
Study NCT04732598 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel + bevacizumab + atezolizumab
Description: The following regimen will be continued as a 28-day course until disease progression or the criteria for treatment discontinuation are met.~\[Atezolizumab\] 840 mg/body, day 1,15, IV \[Paclitaxel\] 90mg/m\^2, day1,8,15, IV \[Bevacizumab\] 10mg/kg, day1,15, IV
Study NCT04996030 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Arsenic Trioxide
Description: IV ATO will be administered per dose and schedule specified in arm description.
Study NCT05672563 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Saline infusion sonography for evaluation of cesarean scar
Description: The intervention included the usage of balloon-less GIS catheter with a soft tapered tip inserted into the endocervical canal, with no use of a tenaculum or a cervical dilatator. Normal saline is slowly introduced into the uterine cavity via the catheter until achieving satisfactory distension and visualization of the uterine cavity using trans-vaginal ultra-sonographic imaging.
Study NCT05076227 — intervention group
Intervention type: DRUG
Intervention: IM injection of vaccination (mRNA vaccination)
Description: mRNA vaccination
Study NCT05362500 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glycolic Acid 70%
Description: Group A: contain 27 patients which had been treated every 2 weeks for 12 weeks with 70% glycolic acid to assess chemical peeling and cold water was used for washing
Study NCT05362500 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tranexamic acid injection
Description: Group B: contain 27 patients treated with an intradermal injection of 0.05 mL of tranexamic acid solution in normal saline (4 mg/mL) into the melasma lesion at 1 cm distance using a sterile insulin syringe, weekly for 12 weeks
Study NCT05470192 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Qigong exercise training
Description: Before and after the qigong exercises, 10-minute exercises will be done to stretch the large muscle groups for warm-up-cooling purposes.~The entire Baduanjin exercise consists of 8 postures:~preparation position~1. Raising arms with palms up,~2. Shooting arrows left and right like an archer in a semi-crouching position~3. Keeping one arm up~4. Looking back with trunk rotations in a semi-crouching position~5. Nodding the head and lowering the body to relieve stress,~6. Fisting and staring~7. Touching feet with hands touching back and legs~8. Raising and lowering heels
Study NCT05076227 — intervention group
Intervention type: DRUG
Intervention: IM injection of vaccination (vector based vaccination)
Description: vector based vaccination
Study NCT06505109 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RESST
Description: Subjects randomized to the RESST intervention will receive on top of standard rehabilitation a behavioural group intervention focussing on improving sleep and stress. This intervention will consist of 5 till 6 meetings of 90 till 120 minutes in the local rehabilitation centre during a time period of 3 till 4 months.
Study NCT05326815 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: N-Telopeptide, Bone Marker
Description: This is a prospective specimen collection cohort study to evaluate the correlation between serum and urine values of the bone marker of interest (N-Telopeptide), and their association with baseline DEXA scan measures and fracture risk within 6 months.~Study samples will be obtained longitudinally. One collection of both serum and urine collection will be obtained. The urine will be collected as second void of day and at the same time the blood collection is drawn.
Study NCT04631900 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Christianity approach as framework for spiritual intervention
Description: Intervention includes use of Bible verses, prayer, hymns singing, sharing and caring for others (mutual support) within the group. Through these activities, participants have opportunities to re-build and further develop their connectedness to themselves, to others, to their living, their environment, and to larger meaning and purpose.
Study NCT05390021 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: PET/MRI with radiotracer ([18F]- fluorodeoxyglucose) and a gadolinium-based contrast agent
Description: The research study procedures include a screening for eligibility and a single study visit. PET/MRI in one study visit of approximately four hours.
Study NCT05635305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zoliflodacin Patheon
Description: Zoliflodacin Patheon formulation to be compared with Zoliflodacin Dr Reddy's formulation during BE study (cohort 1).~Itraconazole will be administered with Zoliflodacin Patheon formulation during DDI study (cohort 2)
Study NCT06390878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biodiversity
Description: In rewilding kindergartens, the yards are modified with biological elements, i.e., vegetation and plantation will be added to the yards.
Study NCT06390878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Playground equipment
Description: Playground equipment that increase the physical activity of children will be added to the kindergarten yards.
Study NCT06059638 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Medtronic Astra/Azure DR MRI IPG with AVIM therapy Activated
Description: Antihypertensive therapy utilizing atrioventricular interval modulation.
Study NCT06059638 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Medtronic Astra/Azure DR MRI IPG with AVIM therapy Deactivated
Description: AVIM therapy is deactivated
Study NCT05526521 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Injection solution Subcutaneous
Study NCT05287711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivational Enhancement Therapy
Description: In Session 1, the therapist provides personalized feedback on a range of assessment variables, including alcohol consumption levels, negative consequences from alcohol use, and family risk of alcoholism. Sessions 2-4 are follow-through sessions in which the therapist attempts to help the Veteran participant establish or reaffirm a commitment to an action plan for addressing alcohol concerns.
Study NCT05287711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Alcohol Education Control
Description: Will consist of 4 weekly individual sessions, approximately 60 minutes each. AE therapists will explain that their job is to provide the Veteran participants with information and education about the effects of alcohol, and that it is up to the Veteran participant to use this information as he sees fit. In each session, the Veteran participant will watch an educational videotape in a comfortable consulting room and will be given an opportunity to discuss the videotape with the project therapist for approximately 10 minutes. Written educational materials will supplement the information provided in the videos, and the therapist will ask several structured questions to determine whether the Veteran participant understood the material presented in the video.
Study NCT04745351 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remdesivir
Description: Administered as Intravenous (IV) infusion once daily
Study NCT04745351 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: RDV Placebo
Description: Administered as IV saline once daily
Study NCT04745351 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Standard of Care
Description: Standard of Care Treatment for COVID-19 Infection
Study NCT04745351 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: Standard of Care Treatment for COVID-19 Infection
Study NCT05287711 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Treatment as Usual
Description: Supportive telephone monitoring sessions that ensure equal spacing between assessments across conditions and equal number of therapist contacts.
Study NCT05287711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strength at Home
Description: IPV intervention which consists of 12 weekly, 2-hour cognitive-behavioral sessions offered in a closed group format and co-led by doctoral level male and female therapists. Strength at Home is based on a social information processing model of trauma and IPV and provides material covering psychoeducation regarding trauma and IPV, conflict and anger management skills, assertiveness training, and skills in stress management and communication.
Study NCT05287711 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Strength at Home
Description: IPV intervention which consists of 12 weekly, 2-hour cognitive-behavioral sessions offered in a closed group format and co-led by doctoral level male and female therapists. Strength at Home is based on a social information processing model of trauma and IPV and provides material covering psychoeducation regarding trauma and IPV, conflict and anger management skills, assertiveness training, and skills in stress management and communication.
Study NCT05090644 — intervention group
Intervention type: GENETIC
Intervention: DNA analysis
Description: GWAS
Study NCT05669157 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiography request by nurse
Description: Intervention group with radiography requested by the IRN instead of the physician. The radiography will be interpreted by the physician afterwards, according to current practice
Study NCT05669157 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radiography request by physician
Description: The physician prescribed the X-ray, the X-ray technician carries out the imagery and the physician interprets it afterwards
Study NCT06609629 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Selective lung recruitment
Description: A bronchial blocker with a lumen is inserted in one inferior pulmonary lobe using a fibroscope. The baloon of the blocker is expended to isolate the lobe. A second ventilator is used to apply a pressure of 45cmH2o through the lumen of the blocker. The recruiting pressure is maintained 30 to 60 second. After the procedure, the blocker is removed and the procedure is repeated in the controlateral inferior lobe.
Study NCT06610331 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: FREE GİNGİVAL GRAFT
Description: Free Gingival Graft removal from the palate donor area for the treatment of gingival recession
Study NCT06610331 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: FREE GİNGİVAL GRAFT
Description: Free Gingival Graft removal from the palate donor area for the treatment of gingival recession
Study NCT06610331 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: polyvinylpyrrolidone sodium hyaluronate gel
Description: Patients are told to gargle with a mouthwash containing polyvinyl pyrrolidone sodium hyaluronate twice a day for 2 weeks. 15 ml (1 tablespoon) of mouthwash containing polyvinyl pyrrolidone sodium hyaluronate is poured into a glass and approximately 40 ml (3 tablespoons) of water is added and mixed well, then it is shaken for at least 1 minute, making contact with the entire mouth.
Study NCT06610656 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pacifier and White Noise Therapy
Description: Infants will receive both pacifier and white noise therapy to enhance sleep quality and reduce restlessness
Study NCT06610656 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: pacifier therapy
Description: Infants will receive pacifier therapy to enhance sleep quality and reduce restlessness
Study NCT06611878 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music training - intensive
Description: Music training entails learning novel songs the participant chooses from a list. Songs are similar in complexity and length (number of words, high frequency words, harmony, musical complexity, length of verses and chorus). Offering a variety of songs allows to examine memory performance regardless of the specific song chosen. Sessions last 30 to 40 minutes, conducted based on a manual (1. mood observation; 2. warm-up; 3. teaching the chorus, observed liking of song; 4. singing entire chorus; 5. singing chorus in context, 6. session closure with favourite song; 7. final mood observation; session rating), and are video-recorded. External evaluators audit the sessions video recordings to determine adherence to the manual. Sessions are offered twice a week for 5 months.