AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05510453 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low-intensity online intervention (LiON)
Description: The LiON in the current study is comprised of three core modules identified to be core areas of stress and needs of participants based on clinical experiences of the research team. The three modules include (1) stress management, (2) sleep and relaxation, and (3) problem-solving skills.~Each module consists of four 1-on-1 sessions which will be conducted through online platforms (such as Zoom) that lasts for 45 minutes. Participants will attend these sessions once a week.~The control group will receive the intervention after a waiting period of 4 weeks.
Study NCT05510453 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Low-intensity online intervention (LiON)
Description: The LiON in the current study is comprised of three core modules identified to be core areas of stress and needs of participants based on clinical experiences of the research team. The three modules include (1) stress management, (2) sleep and relaxation, and (3) problem-solving skills.~Each module consists of four 1-on-1 sessions which will be conducted through online platforms (such as Zoom) that lasts for 45 minutes. Participants will attend these sessions once a week.~The control group will receive the intervention after a waiting period of 4 weeks.
Study NCT05970458 — intervention group
Intervention type: OTHER
Intervention: Quality of life assessment
Description: EQ5D-5L and Stoma QoL
Study NCT06214312 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Lung Ultrasounds
Description: An ultrasound exam of the lungs to identify possible areas of atelectasis.
Study NCT05628844 — intervention group
Intervention type: PROCEDURE
Intervention: Continuous enteral feeding
Description: Enteral nutrition by continuous infusion for 10 hrs at a dose corresponding to 25 kcal/kg body weight/day
Study NCT04739371 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The spray will last a few seconds and then the participant will be asked to sniff to aid the saline into the nose. The device (i.e. ViaNase) is an atomizer that uses its patented technology that turns the liquid into a fine mist of droplets to facilitate the drug along the nose to brain pathway. Each nostril will receive this administration 2 times for a total of 40 IUs or 0.4 mL of liquid.
Study NCT05153889 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Hospitalized in Intensive care unit
Description: Patient hospitalized in Intensive care unit with ECG monitoring
Study NCT05153889 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hospitalized in General cardiology ward
Description: Patient hospitalized in General cardiology ward without ECG monitoring. patients randomized in this group will not be hospitalized in intensive care unit unless an event require intensive care unit monitoring.
Study NCT05640076 — intervention group
Intervention type: OTHER
Intervention: 24/7 Telephonic Palliative Care Service availability
Description: Metropolitan Palliative Care Service-implemented 24/7 telephonic availability service for the patients, their relatives, the EMS and Primary Care physicians taking care of them.~After consultation, if the information and medical suggestions are not sufficient, an urgent ambulatory or home visit could be planned.
Study NCT04825522 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: During spinal surgery, participants will receive intrawound vancomycin powder in their wound before closure.
Study NCT06090240 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MI-based ACP intervention
Description: Motivational Interviewing on Advance Care Planning Intervention: Dyads of older adults and family caregivers will receive three MI-based ACP counselling sessions: (1) a preparatory session, (2) motivation session, and (3) planning session. The preparatory session will take 10-15 minutes, and the following two sessions in weeks 2 and 3 will last 30-45 minutes each. Before each session, the nurse interventionist will first assess the dyad's readiness to engage in ACP based on the state of change algorithm. Participants who have never thought about ACP will be in the pre-contemplation state, those who are willing to discuss EOL care and preferences to be in the contemplation state, those ready to talk about EOL planning to be in the preparation state, and those in the action state have a confirmed action plan on signing up their ADs. Readiness-based ACP goals will be established, and state-matched MI counseling will be customized for each participant.
Study NCT06301360 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet based Emotional Awareness and Expression Therapy (I-EAET)
Description: In I-EAET with therapist support, the therapist and participants communicate asynchronous using written messages. The therapist gives feedback each week on home-work assignments and is available on demand for support.~In I-EAET without therapist support, the participants works with home-work assignments on their own and only have technical support.
Study NCT06301360 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Internet based Emotional Awareness and Expression Therapy (I-EAET)
Description: In I-EAET with therapist support, the therapist and participants communicate asynchronous using written messages. The therapist gives feedback each week on home-work assignments and is available on demand for support.~In I-EAET without therapist support, the participants works with home-work assignments on their own and only have technical support.
Study NCT05111314 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Gallium Ga 68 Gozetotide
Description: Given IA
Study NCT05111314 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hepatic Artery Embolization
Description: Undergo hepatic artery embolization
Study NCT05111314 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positron Emission Tomography and Computed Tomography Scan
Description: Undergo PET/CT scan
Study NCT04751721 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CoronoVac Vaccine
Description: CoronaVac vaccines will be inoculated in 2 doses with an interval of 24 days.
Study NCT04999787 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542
Description: HSK21542-0.3 μg/kg，HSK21542-0.6 μg/kg
Study NCT04999787 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05727644 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NNC0194-0499
Description: Participants will receive a single subcutaneous injection of 30 mg NNC0194-0499.
Study NCT05727644 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NNC0194-0499
Description: Participants will receive a single subcutaneous injection of 30 mg NNC0194-0499.
Study NCT05082480 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyaluronic acid (HA)
Description: Hyaluronic acid (HA)
Study NCT05082480 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: Saline
Study NCT06451783 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Traditional Chinese medicine combined with manipulation treatment
Description: The specific procedure involves administering the Shengyu Decoction, which consists of the following herbs:~* Shu Di Huang 20 grams~* Bai Shao 15 grams~* Dang Gui 15 grams~* Chuan Xiong 8 grams~* Ren Shen 20 grams~* Huang Qi 18 grams One dose is taken per day, and a course of treatment consists of five weeks. Add manipulation of massage：~  * Press and grasp the affected limb three times；~    * Five-finger five-acupoint pressing method；~      * Point pressing on Zusanli (ST36) and Sanyinjiao (SP6)；~        * grasp the interior method to treat the calf three times；~          ⑤ Apply rolling technique around the knee joint；~          ⑥ Knead and straighten the standing tendon (the lateral muscle of the calf)；~          ⑦ Six-finger six-acupoint pressing method；~          ⑧ Push and pull the patella to flex and extend the knee joint；~          ⑨ Knee joint reunion and smooth dispersion method.
Study NCT06451783 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Celecoxib capsule
Description: Oral Celecoxib Capsules, 200mg per dose, once daily after lunch.
Study NCT05504772 — intervention group
Intervention type: GENETIC
Intervention: Whole Genome Sequencing
Description: Each tumor sample will be sequenced and analyzed in parallel with its matched normal (germline DNA from the same patient) to enable the identification of somatic aberrations.
Study NCT05690516 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Wearing face masks
Description: Participants are asked to wear face masks in public spaces.
Study NCT05663411 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR6508
Description: SHR6508
Study NCT05663411 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cinacalcet
Description: Cinacalcet
Study NCT05316428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TPN171H tablet plus alcohol
Description: 10 mg TPN171H tablet QD plus 0.5 g/kg alcohol
Study NCT05316428 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: alcohol
Description: 0.5 g/kg alcohol
Study NCT05316428 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TPN171H tablet
Description: 10 mg TPN171H tablet QD
Study NCT05926570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cinacalcet
Description: calcimimetic
Study NCT06099340 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: muscle-strengthening program
Description: a muscle-strengthening program applied to the ankle muscles (triceps surae and dorsal flexors) in physiotherapy, as a complement to conventional rehabilitation
Study NCT06099340 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: muscle-strengthening program
Description: a muscle-strengthening program applied to the ankle muscles (triceps surae and dorsal flexors) in physiotherapy, as a complement to conventional rehabilitation
Study NCT05358860 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sofwave
Description: The Sofwave System, comprised of an applicator and a console, generates high intensity, non-focused ultrasonic energy which can be delivered percutaneously to tissues.
Study NCT05069961 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: ESPB
Description: Ropivacaine is injected near the nerves in the back
Study NCT05069961 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TEA
Description: Bupivacaine is injected into the space around the spinal cord.
Study NCT05105945 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery
Description: Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery dissects, dissociates and removes the esophagus in the mediastinum through an inflatable endoscopy. Detailed surgical procedures and related instructions have been published in Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery for Radical Esophagectomy Is an Effective and Safe Treatment for Esophageal Cancer J Gastrointest Surg. 2019 Aug;23(8):1533-1540. doi: 10.1007/s11605-018-04069-w. Epub 2019 Jan 11.
Study NCT05105945 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Thoracoscopy Combined With Laparoscopic Surgery
Description: Patients will receive a standardized thoracoscopy and laparoscopy combined radical esophageal cancer surgery
Study NCT06217224 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preventive photobiomodulation Therapy (PBMT)
Description: The application of preventive TLBP will be performed with a laser device containing an aluminum phosphide and indium gallium diode (InGaAlP) emitting radiation in the red region of the electromagnetic spectrum (660 nm) with a power of 100mW and a beam area of 0.03 cm2 . An energy of 1J/point and an energy density of 33.3 J/cm2/point were determined, which will be applied punctually, with a distance between the points of 1cm, for 10s per point, totaling 9 points per region.
Study NCT06217224 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Preventive photobiomodulation Therapy (PBMT)
Description: The application of preventive TLBP will be performed with a laser device containing an aluminum phosphide and indium gallium diode (InGaAlP) emitting radiation in the red region of the electromagnetic spectrum (660 nm) with a power of 100mW and a beam area of 0.03 cm2 . An energy of 1J/point and an energy density of 33.3 J/cm2/point were determined, which will be applied punctually, with a distance between the points of 1cm, for 10s per point, totaling 9 points per region.
Study NCT03948022 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dydrogesterone 10Mg Tablet (duphaston)
Description: 40 mg daily oral tablets
Study NCT03948022 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Progesterone 50Mg/mL Oil
Description: 100 mg daily intramuscular injections
Study NCT03948022 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Crinone 8% Vaginal Gel
Description: 180 mg daily vaginal gels
Study NCT04657965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LMP1 CAR T-cells
Description: Each subject receive LMP1 CAR T-cells by intravenous infusion
Study NCT06192303 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bronchoalveolar lavage and pathogen metagenomic sequencing
Description: After the patient is enrolled, traditional pathogen testing will be improved, and the clinical physician will make a preliminary diagnosis based on routine pathogen testing, clinical manifestations, infection indicators, and imaging. Within 24 hours of initial diagnosis, bronchoalveolar lavage and pathogen metagenomic sequencing were performed, and BALF mNGS results were fed back to clinical physicians (without interfering with clinical decision-making). Clinical treatment data of patients were collected at 72 hours, 7 days, 14 days, and 28 days after the start of treatment, and follow-up and efficacy evaluation were conducted. Finally, a review committee consisting of two senior respiratory physicians and one imaging physician conducted a systematic review of cases to make the final diagnosis of enrolled patients (as the gold standard), analyzing the accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of BALF mNGS in diagnosing CIP.
Study NCT06326944 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound- guided Fascia Transversalis plane block
Description: Ultrasound probe will be placed in a transverse orientation above the iliac crest; and the external oblique, internal oblique (IO), and transversus abdominis TA muscles will be identified and traced posteriorly until first the TA muscle and then the IO muscle tapered into their common aponeurosis, adjacent to the quadratus lumborum muscle. The tip of a 22-gauge 80-mm block needle will be positioned just deep to the TA muscle and its aponeurosis at the point where the TA is tapered off. 0.4 ml/kg bupivacaine 0.25% will be injected into the plane between the TA and underlying transversalis fascia
Study NCT06326944 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound-guided Transversus abdominus plane block
Description: the probe will be placed transversely in the mid-axillary line between the iliac crest and the costal margin at the level of the umbilicus. The external oblique, internal oblique and transversus abdominis muscles and their fascias will be visualized. A 22 gauge, 80 mm needle will be introduced anteriorly and in the plane of the ultrasound probe, and on entering the plane between IO and TA, 2 ml of 0.9% saline will be injected to verify the correct position of the needle. Following negative aspiration, 0.4 ml/kg of bupivacaine 0.25% will be injected.
Study NCT06326944 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fentanyl
Description: patients will receive an induction dose at 1 mcg/kg. If the analgesia was inadequate in the form of increase in heart rate and or arterial blood pressure by more than 20% of baseline values during surgery, this warrants the administration of intravenous fentanyl (0.5µg/kg).
Study NCT06326944 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pethidine
Description: Pethidine IV will be given as rescue analgesia (0.5 mg/kg) if the FLACC pain score was more than 4 , the maximum allowed dose is 1mg/kg every 4 hours.
Study NCT06326944 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen
Description: patients will be given paracetamol (15 mg /kg/8 hrs ).
Study NCT04469569 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: HPV-PROTECT
Description: HPV-PROTECT is a multicomponent provider-focused intervention specifically tailored for use in pediatric oncology settings, addressing important survivor-specific vaccine issues. The intervention is comprised of three components, i) Provider Communication Training; ii) Assessment and Peer Feedback/ Coaching; and iii) Provider Toolkit. The HPV-PROTECT intervention is designed to increase provider knowledge regarding use of the HPV vaccine in the cancer survivor population, enhance provider skills in delivering brief, compelling HPV vaccine recommendations to parents of young cancer survivors, present ongoing feedback to providers regarding clinic- and provider-level survivor HPV vaccination rates, and decrease barriers to receipt of vaccine by survivors through the provision of Vaccine Action Plans, tailored to local context.
Study NCT05525468 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TDM-180935
Description: TDM-180935 topical ointment
Study NCT05525468 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for TDM-180935 topical ointment
Study NCT05144425 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: total knee arthroplasty with and without using pneumatic tourniquet
Description: The randomization will be performed by a research fellow who will not be involved in patient care. All of the operations will be performed through the medial parapatellar approach by experienced knee surgeons. Drainage system will be used for 48 hours postoperative. In the tourniquet group, the tourniquet will be inflated to a pressure of systolic blood pressure plus 100 mm Hg and will be released after the joint capsule has been closed. hemostasis and then will be wrapped with elastic bandages. In the non-tourniquet group, the tourniquet will be wrapped around the thigh but will not be inflated during the surgery. The criterion for a blood transfusion will set as a hemoglobin (Hb) level of\<8 g/dL or patient with symptomatic anemia.
Study NCT05144425 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: total knee arthroplasty with and without using pneumatic tourniquet
Description: The randomization will be performed by a research fellow who will not be involved in patient care. All of the operations will be performed through the medial parapatellar approach by experienced knee surgeons. Drainage system will be used for 48 hours postoperative. In the tourniquet group, the tourniquet will be inflated to a pressure of systolic blood pressure plus 100 mm Hg and will be released after the joint capsule has been closed. hemostasis and then will be wrapped with elastic bandages. In the non-tourniquet group, the tourniquet will be wrapped around the thigh but will not be inflated during the surgery. The criterion for a blood transfusion will set as a hemoglobin (Hb) level of\<8 g/dL or patient with symptomatic anemia.
Study NCT05213871 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Instrument-assisted soft tissue mobilization
Description: For IASTM, the subject will be seated in a comfortable position. The subject's forehead will be rested on his/her forearm on a table in front of him/her. A lubricant (Vaseline) will be applied to the skin around the neck area prior to treatment and the M2T blade will be cleaned with an alcohol pad. The M2T blade will be used, at an angle of 45 without causing discomfort or pain, from the muscle origin to its insertion (sweeping technique), for approximately 3 min. Subjects will be instructed to put an ice pack on the area if they feel any burning sensations after the session. This procedure will be repeated twice a week for four weeks.
Study NCT05213871 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Myofascial release therapy
Description: Firstly, the subject will lay supine with no pillow under his/ her head then the subject will rotate his/her head and neck away from the side which will be treated. Therapist will sit or stand at the corner, edge or top of the treatment table and therapist will place one hand proximal to the shoulder with skin on skin and therapist's fingers pointing towards the subject's elbow on the same side. Other hand of the therapist will be placed inferior to the subject's jaw (body of the mandible), using it as a handle, with fingers pointing towards the top of the subject's head. Then therapist will lean into the subject to the tissue depth barrier, wait and follow each subtle release three-dimensionally. Therapist should avoid forcing the tissue or slipping or gliding over the skin. The technique should be applied for at least five minutes for optimal results. This procedure will be repeated twice a week for four weeks.
Study NCT05213871 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postural correction exercises (PCE)
Description: Postural correction exercises will be applied for patients in groups A and B. This program will be conducted according to the protocols of exercise will be performed as 3 sets of 10 repetitions each for 2 times/ week for 4 weeks. The patients will be instructed to continue the exercises as a daily home program to influence the self-correction kinesthetic awareness. Exercises will be performed while the patients in a neutral sitting posture
Study NCT04256408 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bronchoscopic transparenchymal interlobar fissure closure using Aeriseal
Description: Transbronchial or transparenchymal injection of AeriSeal into the interlobar collateral ventilation channels region to convert CV-positive lobes into CV-negative lobes.