AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06201078 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Body Radiotherapy
Description: Salvage SBRT will be performed in three subgroups of patients with local recurrence:~Group A - after conventionally fractionated definitive radiotherapy; Group B - after prostatectomy and postoperative radiotherapy; Group C - after ultrahypofractionated definitive SBRT~Target volumes:~GTV- tumour visible on MRI and PET-CT; CTV- 1-3 mm margin around GTV PTV- 3 mm around CTV\*~\*- in cases in which very high accuracy and reproducibility of SBRT are ensured, and the margin overlaps the rectum and/or bladder, it is possible to reduce the margin from these organs to 1 mm.~Dose constrains:~The criteria for limiting the dose in nearby organs are not well-defined for repeated irradiation - the following doses should be aimed:~* Maximum rectal dose ≤103% of the prescribed dose (optimal ≤100%)~* Maximum bladder dose ≤105% of the prescribed dose (optimal ≤103%)~Dose-volume constrains:~Rectum:~• D30% \<15Gy~Bladder:~• D30% \< 15 Gy
Study NCT05472103 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ergonomics surgical workshop
Description: ergonomics surgical workshop
Study NCT04393311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ulinastatin
Description: Ulinastatin administered via IV infusion (200,000/infusion)
Study NCT04393311 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to match ulinastatin administered via IV infusion
Study NCT06337487 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: QoL questionnaires
Description: The EORTC QLQ-C30 questionnaire is a specific cancer questionnaire. A score is calculated per dimension reflecting the patient's level for the corresponding QoL scale (dimension). These scores are calculated according to the EORTC recommendations.~Research work was recently developed by Giesinger et al. within the EORTC QoL group, with the aim of providing thresholds of clinical importance for the different dimensions of the QLQ-C30.~An item was added to complete the QLQ-C30. It comes from the EORTC bank library item based on the INCa organizational framework. This item was chosen because it addressed a theme not addressed in the QLQ-C30, sexual health. After consultation with a multidisciplinary team, the threshold was determined for this additional item. Has your illness or treatment had a negative effect on your sex life? , the threshold is reached when the answer is enough or a lot.
Study NCT06337487 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Qualitative Interview (for one part of nurses only)
Description: At the end of the study, semi-directed qualitative interviews will be conducted with the nurses carrying out the TAS with the aim of understanding the obstacles and facilitators of the routine implementation of the QoL assessment to early identify the SOS needs of patients treated in medical oncology. The semi-structured interviews will be accompanied by an interview grid composed of main questions and follow-up questions. The main questions help introduce the theme. The follow-up questions make it possible to clarify the participants' comments without interrupting the fluidity of the exchanges. The themes discussed between the researcher and the participant during the interview will be as follows: Personal information and overall professional experiences, Knowledge of the study and experience of training with tools (questionnaire and software), Perception of tools (questionnaire and software) and their implementation, Definition and perception of key concepts.
Study NCT06337487 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: ORIC questionnaire
Description: Organisational readiness is a factor known to influence the predisposition of individuals to change within an organisation. Based on Weiner's organisational theory, Organizational Readiness for Implementing Change (ORIC) is a questionnaire that has been developed and validated, particularly in French, to measure the organisation's state of in the field of healthcare. It comprises ten items which measure two concepts: commitment to change and effectiveness of change.
Study NCT06337487 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Professionals satisfaction survey
Description: A satisfaction questionnaire will be offered to all professionals involved once the last patient has been included. This questionnaire has previously been developed by the UMQVC team to assess investigator satisfaction for other studies and adapted to the context of SOS-Deteqt.~This questionnaire evaluates in particular :~* the quality of training~* ease of use of the CHES~* the relevance of using the CHES and the PROs~* the relevance of maintaining the PRO evaluation approach in current clinical practice.
Study NCT06337487 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patients satisfaction survey
Description: A patient satisfaction questionnaire was drawn up for the study. It includes items taken from :~* the EORTC's PATSAT33 satisfaction questionnaire, and in particular items relating to the quality of information provided by nurses and the time spent~* the EORTC COMU26 communication evaluation questionnaire, and in particular the items on being comfortable asking questions, professional responses to difficult difficult subjects, explanation of treatment objectives, etc.~* the questionnaire developed jointly by the UMQVC team and the psychology laboratory of the psychology laboratory at the University of Franche Comté as part of the REMOQOL-Poumon study and assessing in particular~* understanding of the purpose of using the QoL questionnaire~* ease of completion and use of the tablet~* satisfaction with the questionnaire and the tablet~* intention to use in the future
Study NCT06311370 — intervention group
Intervention type: OTHER
Intervention: Observation
Description: Observed by trained staff and wearing a sensor watch
Study NCT05763199 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AHCC
Description: AHCC is the cultured mycelia of Lentinula edodes mushrooms from the Basidiomycetes family.
Study NCT05763199 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Chemotherapy
Description: Chemotherapy will be administered per standard of care.
Study NCT05763199 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: Chemotherapy will be administered per standard of care.
Study NCT05763199 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Dextrin
Study NCT06546917 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: bWell Cognitive Remediation
Description: Patients will take part in the bWell cognitive remediation protocol, consisting of 40-minute sessions of bWell, administered 2 times a week for 8 weeks. These sessions consist of tasks that target various cognitive domains and increase in complexity and difficulty as training progresses. The tasks are as follows:~1. Lab Exercise: participant alternates between two different, increasingly complex 'recipes', targeting executive functioning and divided attention.~2. Egg Exercise: In an office environment, participants must seek out and maintain their gaze on certain objects in order to collect them in the presence of visual distractors, targeting sustained attention.~3. Mole Exercise: participants must strike moles with the matching coloured hammer as fast as possible, targeting selective attention.~4. Theatre Exercise: participants must remember objects presented on stage and recreate the sequence after the curtains close, targeting working memory.
Study NCT06546917 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: VR Experience
Description: Patients will take part in the viewing of VR scenes which contain no instructed cognitive tasks. This consists of 40-minute sessions of viewing VR scenes, administered 2 times a week for 8 weeks.
Study NCT04990778 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eprenetapopt
Description: Given IV
Study NCT04990778 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT04853615 — intervention group
Intervention type: DRUG
Intervention: Empagliflozin 25 MG
Description: PAtient will receive empagliflozin 25 mg daily
Study NCT06509360 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Feelee app
Description: Adolescents uses the Feelee app for 4-weeks in addition to treatment as usual in the forensic outpatient setting. The use of Feelee involves: submitting one emoji every day and allow the Feelee app to read the following passive data from the health app on the smartphone: number of steps and number of hours of sleep. The collected Feelee data will be presented in a dashboard in the Feelee app itself which will be discussed by the clinician in the weekly treatment session (in case the adolescents agreed to show the Feelee data to the clinician).
Study NCT05698251 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Uncertainty distress model
Description: Psychological therapy intervention based on elements of traditional Cognitive Behaviour Therapy (CBT) for anxiety, illness uncertainty and intolerance of uncertainty.
Study NCT06146478 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thalidomide
Description: Thalidomide given at an average dose of 1.5mg/kg/day
Study NCT02978677 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy 68 Gy(RBE)
Description: Radiotherapy 2.0 to 50 Gy(RBE) photon or proton and boost 2 to 18 Gy(RBE) proton
Study NCT02978677 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy 72 Gy(RBE)
Description: Radiotherapy 2.0 to 50 Gy(RBE) photon or proton and boost 2 to 18 Gy(RBE) proton and boost 2 to 4 Gy(RBE) proton
Study NCT02978677 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiotherapy 60 Gy(RBE)
Description: Radiotherapy 2.0 to 50 Gy(RBE) photon or proton and boost 2 to 10 Gy(RBE) proton
Study NCT05563389 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin 20mg
Description: active arm
Study NCT05563389 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo arm
Study NCT04977115 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraocular caliper-assisted capsulotomy
Description: Intraocular caliper is a modified intraocular caliper with standard calibration on the rinse needle.
Study NCT04977115 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Verion navigation system-assisted capsulotomy
Description: Verion Image Guided System (Alcon Laboratories, Inc.) is a digital image guidance system consisting of a diagnostic reference unit and a surgery pilot for intraoperative surgical assistance. The device can be used to align toric intraocular lens during surgery as well as support manual creation of a capsulorhexis with a predefined target diameter.
Study NCT03088774 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Information material
Description: Online web-application developed together with patients with low back pain
Study NCT04699942 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional (low flow) oxygen delivery via nasal cannula
Description: Conventional (low flow) oxygen delivery via nasal cannula or face mask for 20 minutes
Study NCT04699942 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Revoxa Oxygen Rebrearther
Description: Oxygen delivery via Revoxa Oxygen Rebreather device for 20 minutes
Study NCT06544356 — intervention group
Intervention type: OTHER
Intervention: No intervention, questionnaire filled out
Description: Mother introductory information form, Health Literacy Scale, Knowledge and Attitude Scale about Newborn Screenings were completed.
Study NCT05681273 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chiglitazar
Description: Chiglitazar 48mg
Study NCT05681273 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin
Description: Empagliflozin 10mg
Study NCT05681273 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin
Description: Atorvastatin 20mg
Study NCT05681273 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Valsartan
Description: Valsartan 160mg
Study NCT06026475 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Goal directed Fluid Therapy
Description: Patients will receive fluid during surgery with goal of maintaining SVV below 11
Study NCT06026475 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Fluid Therapy
Description: Patients will receive fluid during surgery with goal of maintaining CVP between 8-12 cms H20
Study NCT00909129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pegylated interferon-alpha (Pegasys)
Description: Pegylated interferon-alpha 2a 180 micrograms s.c. weekly
Study NCT00909129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ribavirin (COPEGUS)
Description: ribavirin bid 800-1200 mg depending on HCV genotype and body weight
Study NCT05575817 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web Based Patient Tutorial on Prolonged Grief Disorder Therapy
Description: The patient tutorial will contain 9 modules, each designed to be used flexibly in conjunction with Prolonged Grief Disorder Therapy (PGDT) telehealth sessions with the therapist. Each module takes about 15-30 minutes to complete. The patient tutorial consists of information about grief and adaptation to loss, including a description of seven healing milestones that are the focus of PGDT and an explanation of prolonged grief and how to understand it. In addition, the tutorial has descriptions of the procedure, goals and rationale for a series of in-session therapeutic exercises to be undertaken with the therapist, as well as descriptions and encouragement to participate in interim therapeutic activities (i.e., homework) assigned by the therapist after each treatment session. The tutorial also contains a self-assessment component for each module that can be completed by the patient and shared with the therapist.
Study NCT05426993 — intervention group
Intervention type: OTHER
Intervention: Complex decongestive physiotherapy
Description: CDT is a treatment approach consisting of manual lymph drainage, skin care, compression bandage and exercises.
Study NCT05760521 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Provider Educational Intervention
Description: Following the informed consent (10 min) and sociodemographic survey (5 minutes), the providers in Arm A will be offered education of two days, six hours each day, with support and follow-up. They will also be asked to complete brief knowledge and confidence surveys pre-post-intervention (30 minutes total).
Study NCT05457166 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KASPARD system for fall prevention in nursing homes
Description: All subjects will be monitored for 2 periods of 100 nights each. Recordings will be made continuously at night for the duration of the study Period 0: set-up, adjustment, recording (without alarm); This is a preparatory phase which is part of the usual use of the device.~Duration: 10 days Before period: The BEFORE period runs for 100 nights during which the device alarm is not activated, but the device records events.~After period: The AFTER period is 100 nights during which the device alarm is activated: Monitoring with recording + alarm activated (usual care + action if alarm is triggered)
Study NCT06314139 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: continuous theta-burst stimulation (cTBS)
Description: Continuous theta-burst stimulation (cTBS) was performed with a CCY-I Magnetic Stimulator (YIRUIDE Medical Co., Wuhan, China) with an air-cooled, figure-of-eight 70 mm coil. The site of stimulation during the TMS treatment sessions was bilateral M1 and cerebellum. Real cerebellar cTBS was delivered with the coil positioned over the cerebellar hemisphere, i.e., 3 cm laterally to and 1 cm below the inion. The cTBS protocol uses a complex pattern of stimulation consisting of three-pulse bursts at 50 Hz repeated every 200ms. A total of 600 pulses that lasts for about 40 seconds were applied which could result in a sustained reduction in corticospinal excitability that outlasted the period of stimulation by 45 min. It was delivered at an intensity corresponding to 80 % of the active motor threshold (AMT), this is the minimum stimulation intensity that evokes MEPs of approximately 200 μV in amplitude in tonically contracted muscles.
Study NCT06314139 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: continuous theta-burst stimulation (cTBS)
Description: Continuous theta-burst stimulation (cTBS) was performed with a CCY-I Magnetic Stimulator (YIRUIDE Medical Co., Wuhan, China) with an air-cooled, figure-of-eight 70 mm coil. The site of stimulation during the TMS treatment sessions was bilateral M1 and cerebellum. Real cerebellar cTBS was delivered with the coil positioned over the cerebellar hemisphere, i.e., 3 cm laterally to and 1 cm below the inion. The cTBS protocol uses a complex pattern of stimulation consisting of three-pulse bursts at 50 Hz repeated every 200ms. A total of 600 pulses that lasts for about 40 seconds were applied which could result in a sustained reduction in corticospinal excitability that outlasted the period of stimulation by 45 min. It was delivered at an intensity corresponding to 80 % of the active motor threshold (AMT), this is the minimum stimulation intensity that evokes MEPs of approximately 200 μV in amplitude in tonically contracted muscles.
Study NCT06545279 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hall Crown Technique
Description: preformed metal crowns (PMCs) cemented with no local anesthesia, caries removal or tooth preparation.
Study NCT06545279 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Modified Hall Technique
Description: preformed metal crowns (PMCs) cemented with no local anesthesia, caries removal or tooth preparation but with interproximal slicing.
Study NCT04883112 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Magnetic Tape®
Description: Magnetic tape® is applied without creating any tension over low back
Study NCT04883112 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Kinesiology Tape
Description: Kinesiology tape is applied without creating any tension over low back
Study NCT06001853 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BM-MSC injection
Description: BM-MSCs at the dose 10 x 106 in 1 ml per facet joint for a total of 2 joints
Study NCT06001853 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: DSMO Injection
Description: After 6 months, patients randomized to Arm B: DMSO will be unblinded and re-assigned to Arm A: treatment then be followed for 12 months.
Study NCT05811299 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Total of 8 sessions for 4 weeks 2 sessions in a week.
Study NCT05811299 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abominal exercises
Description: Total of 8 sessions for 4 weeks 2 sessions in a week.
Study NCT05811299 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Abominal exercises
Description: Total of 8 sessions for 4 weeks 2 sessions in a week.
Study NCT06077903 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GT101
Description: Autologous tumor infiltrating lymphocyte injection
Study NCT05196282 — intervention group
Intervention type: OTHER
Intervention: Smoking cessation
Description: Patients are forced to stop smoking
Study NCT05424354 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Altrazeal (R) Transforming Powder Dressing
Description: After informed consent and the subject is determined to meet all selection criteria, randomization will occur in a 1:1 ratio, to determine the treatment arm of the study. Half of those randomized will receive burn care with Altrazeal TPD.
Study NCT05424354 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care burn dressing
Description: After informed consent and the subject is determined to meet all selection criteria, randomization will occur in a 1:1 ratio, to determine the treatment arm of the study. Half of those randomized will receive burn care with the institution's standard of care burn dressing.
Study NCT06370442 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Intranasal dexmedetomidine, 100mcg
Study NCT06370442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lorazepam
Description: 0.5mg IV
Study NCT06370442 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Haloperidol
Description: 0.5mg IV
Study NCT04779437 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Imagery Cognitive Bias Modification
Description: The imagery cognitive bias modification intervention is derived from that developed via experimental psychopathology research (e.g. Holmes et al., 2009) and adapted for clinical applications in the context of depression (e.g. Blackwell \& Holmes, 2010; Blackwell et al., 2015). The intervention is a series of training sessions in which participants listen to training scenarios consisting of descriptions of everyday situations, structured so that they start ambiguously but always end positively. Participants are instructed to imagine themselves in the situations described as the scenarios unfold. The training aims to train a bias to automatically imagine positive resolutions for ambiguous situations encountered in daily life.~Participants will complete one introductory session of the training with the researcher present (in the outpatient center, or via videoconferencing software), then 8 sessions over two weeks completed from home via the study website.
Study NCT04779437 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Control Training
Description: The cognitive control training is an adaptive Paced Auditory Serial Addition Task (PASAT), adapted from that applied in previous studies (e.g. Siegle et al., 2007; Hoorelbeke et al., 2015; Blackwell et al., 2018). Participants will complete one introductory session of the training with the researcher present (in the outpatient center, or via videoconferencing software), then 8 sessions over two weeks completed from home via the study website.
Study NCT05741190 — intervention group
Intervention type: DEVICE
Intervention: Pentacam Imaging
Description: Imaging of the corneal surface