AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05387889 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Meditation for Pulmonary Hypertension (MMPH)
Description: Eight weeks of Mindfulness Meditation practice for patients with Pulmonary Hypertension condition. The content will focus on how to apply Mindfulness concepts to the everyday management of symptoms and stress.
Study NCT06221852 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ketogenic diet
Description: The ketogenic diet (KD) is a normo-caloric diet composed of high-fat, low carbohydrate, and adequate protein intake. The KD will consist of 3 meals a day plus snacks, targeting 75-80% fat, 13-18% protein, 7% carbohydrates.
Study NCT06221852 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary Guidelines for Americans
Description: Dietary Guidelines for Americans diet is a normo-caloric diet consisting of 3 meals a day plus snacks, emphasizing nutrient dense foods to meet food group needs (85% of calories), and limits foods and beverages higher in added sugars and saturated fat (15% of calories).
Study NCT06424756 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MitoQ
Description: MitoQ supplement is composed of mitoquinol mesylate, which is a synthetic analog of coenzyme Q10
Study NCT06487793 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Insomnia Coach
Description: The intervention combines the Insomnia Coach app with additional brief alcohol intervention to facilitate behavior change for both drinking behavior and insomnia symptoms. Insomnia Coach contains multiple components of CBT-I (e.g., stimulus control, cognitive restructuring, relaxation training, sleep hygiene/psychoeducation, monitoring of sleep via journals). The brief alcohol intervention content added to the CBT-I app is based on CBT skills for moderate drinking, delivered in a motivational enhancement style, and has demonstrated efficacy among young adults and veterans (e.g., correcting perceived norms, use of protective behavioral strategies, challenging expectancies).
Study NCT06487793 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Sleep hygiene comparator
Description: Content is based on sleep hygiene practices, but without additional CBT-I content featured in the experimental condition. There is also not brief alcohol intervention content in the control condition.
Study NCT06424756 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Placebo
Description: MitoQ matched Placebo
Study NCT06424756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MitoTempo
Description: During each experimental visit, intradermal microdialysis will be used to locally infuse MitoTempo (a mitochondria-specific superoxide dismutase mimetic) into the cutaneous microvasculature in the ventral aspect of the left forearm.
Study NCT06424756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tempol
Description: During each experimental visit, intradermal microdialysis will be used to locally infuse Tempol (a superoxide dismutase mimetic) into the cutaneous microvasculature in the ventral aspect of the left forearm.
Study NCT06424756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-NAME
Description: During each experimental visit, L-NAME (nitric oxide synthase inhibitor) will be perfused through microdialysis fibers for quantification of nitric oxide-mediated vasodilation.
Study NCT06424756 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNP - Sodium Nitroprusside
Description: At the end of each experimental visit, SNP will be perfused through microdialysis fibers to elicit a maximal vasodilation response.
Study NCT06464081 — intervention group
Intervention type: OTHER
Intervention: Sleep quality assessment
Description: 1. Pediatric Sleep Questionnaire.
Study NCT06464081 — intervention group
Intervention type: OTHER
Intervention: Anthropometry
Description: 2. Anthropometric data : 2.1 Height; 2.2 Weight; 2.3 Maximal mouth opening; 2.4 Maximal mouth opening with tongue to palate The measures 2.3 and 2.4 will be realized via the Quick Tongue-Tie assessment tool
Study NCT06464081 — intervention group
Intervention type: OTHER
Intervention: Tongue strength assessment
Description: 3. Tongue pressure while swallowing. 4. Tongue peak pressure during tongue elevation. 5. Tongue peak pressure during tongue protrusion. These measures will be realized via the IOPI (Iowa Oral Performance Instrument) device.
Study NCT06464081 — intervention group
Intervention type: OTHER
Intervention: Tongue endurance assessment
Description: 6. The tongue endurance during tongue elevation. 7. The tongue endurance during tongue protrusion. These measures will be realized via the IOPI (Iowa Oral Performance Instrument) device and a timer.
Study NCT06464081 — intervention group
Intervention type: OTHER
Intervention: Orofacial praxis assessment
Description: 8. Motricité Bucco-Linguo-Faciale (MBLF) test.
Study NCT06559033 — intervention group
Intervention type: BIOLOGICAL
Intervention: Evaluation of the presence and number of mutated alleles of the GBA/PSAP genes in patients with MM or MGUS
Description: Estimation of the frequency of variants in the PSAP/GBA genes in patients with MM or MGUS, then comparison with a reference frequency from databases such as the Exome Aggregation Consortium, the Exome Sequencing Project, the 1000 Genomes Project and the dbSNP.
Study NCT06087822 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IMD SiPore21®
Description: The intended use/purpose to improve blood glucose control, as measured by a reduction in HbA1c
Study NCT06087822 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: IMD SiPore21®
Description: The intended use/purpose to improve blood glucose control, as measured by a reduction in HbA1c
Study NCT06482515 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time-restricted eating
Description: Participants will be asked to eat all their food in a self-selected 10-hour eating window every day.
Study NCT06482515 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition counseling
Description: Participants will meet with a nutritionist to discuss their dietary habits and how they compare to the American Cancer Society nutrition guidelines.
Study NCT06482515 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Nutrition counseling
Description: Participants will meet with a nutritionist to discuss their dietary habits and how they compare to the American Cancer Society nutrition guidelines.
Study NCT06268288 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: GammaCore intervention
Description: Use of the vagal nerve stimulator, GammaCore, on the right side of the neck for two 2 minute stimulations performed 3 times a day
Study NCT06268288 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: STEPS management protocol
Description: STEPS is the acronym for the standard management program for our patients with POTS. It includes liberal use of salt, taking in 90-100 ounces of fluid, gradually increasing the duration of aerobic exercise, possible use of one of two prescription medications (metoprolol, and midodrine), and encouragement to set priority and goals
Study NCT06268288 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: STEPS management protocol
Description: STEPS is the acronym for the standard management program for our patients with POTS. It includes liberal use of salt, taking in 90-100 ounces of fluid, gradually increasing the duration of aerobic exercise, possible use of one of two prescription medications (metoprolol, and midodrine), and encouragement to set priority and goals
Study NCT05959551 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: high definition transcranial direct current stimulation (HD-tDCS)
Description: HD-tDCS will be provided for 20 minutes for each stimulation with peak intensity of 2mA.
Study NCT05959551 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high definition transcranial direct current stimulation (HD-tDCS)
Description: HD-tDCS will be provided for 20 minutes for each stimulation with peak intensity of 2mA.
Study NCT06165471 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online and offline blended teaching
Description: The Chaoxing app is an interventional tool, a professional mobile learning platform for smartphones, tablet computers, and other mobile terminals. They will learn the online course on the Chaoxing app and carry out offline classroom learning. The online courses focus on teaching design to make teaching PowerPoint, teaching videos, micro-lessons, homework library, and so on.
Study NCT06165471 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Traditional teaching
Description: The researchers will implement the traditional teaching intervention of a surgical nursing practice course to the control group, and the teacher will demonstrate the operation procedure to the students face to face offline, and the students will practice. The whole intervention time is two months.
Study NCT05307302 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Force Sense
Description: A measure of proprioception, using a handheld dynamometer (MicroFET2-hoggan Health Industries Inc.), in a sitting position in a standardized position of the elbow joint of the dominant upper extremity (90 degree of flexion). Measurement of the elbow joint flexion force sense will be expressed as percentages. Each of the targeted trials will be calculated as a percentage of the maximum voluntary contraction (MVC) reference measure. The difference between the targeted and the actual percentage of MVC for each of the trials will be then calculated as a percentage of the targeted MVC, to reflect the proportion of error.
Study NCT06171633 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: E-STOP online educational program (treatment condition)
Description: Participants access online video modules through an online learning platform. Program includes modules on civility and upstander interventions and education about sexual harassment, microaggressions, and implicit bias.
Study NCT06171633 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: E-STOP online educational program (control condition)
Description: Participants access online video modules through an online learning platform. Program includes authorship ethics only.
Study NCT06268964 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Trimebutine
Description: Prescription of trimebutine at pediatric dosage (15 mg/kg/day), divided into 2 daily doses, for 8 weeks.
Study NCT06268964 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trimebutine
Description: Prescription of trimebutine at pediatric dosage (15 mg/kg/day), divided into 2 daily doses, for 8 weeks.
Study NCT06268964 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Lactobacillus rhamnosus
Description: Prescription of Lactobacillus rhamnosus 5 billion CFUs in chewable tablets, a single dose (night) for 8 weeks.
Study NCT06268964 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus rhamnosus
Description: Prescription of Lactobacillus rhamnosus 5 billion CFUs in chewable tablets, a single dose (night) for 8 weeks.
Study NCT06268964 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Prescription of a placebo, 250 mg microcrystalline cellulose tablets, a single dose (night) for 8 weeks.
Study NCT05787925 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical corticosteroid and Vitamin E
Description: 26 patients who will administrate topical corticosteroid: triamcinolone acetonide 1% oral gel Kenacort-A Orabase \* three times daily for 8 weeks applied after meals and at night with avoidance of foods and drinks for 30 minutes after the application. In addition to one capsule of 400 mg oral systemic vitamin E supplement\* will be prescribed once daily at the morning
Study NCT06658041 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioural therapy (CBT)-based intervention with stepped-care
Description: After initial clinical assessment, participants will be offered interventions based on their depressive symptom severity (Patient Health Questionnaire-9-item \[PHQ-9\]).~Mild symptoms (PHQ-9\<5) without major risks (\*see above): 4 weekly CBT-informed intervention sessions led by trained Emotional Support Assistants (Peer Supporters with 80hrs mental health training + 15hrs intensive clinical training).~Mild symptoms (PHQ-9\<5) with major risk factors or moderate-to-moderately severe symptoms (PHQ-9=10-19): 6 weekly CBT-based intervention sessions led by trained clinical social workers, with 2 booster sessions as necessary. Individual CBT-based intervention will be provided to those unsuitable for group interventions.~In cases of non-remission (PHQ-9≥5): a second intervention trial will be provided. Those needing additional support will be referred to a partnered General Practitioner (if PHQ-9=10-19) or referred to more intensive psychological or psychiatric services as needed.
Study NCT06658041 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Care-as-usual
Description: Following an initial interview session with research assessments, participants continue with their usual care at their primary care setting.
Study NCT05307302 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Joint Reproduction Sense
Description: A measure of proprioception, using a smart phone goniometer (Android Clinometer) application, in a sitting position in a standardized position of the elbow joint of the dominant upper extremity. Measurement of the elbow joint position reproduction will be expressed as degrees of reproduced angle. Absolute Error (AE) score will be calculated by the absolute value of the difference in degrees of the angle reproduced after subtracting the angle targeted.
Study NCT04854356 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise with blood flow restriction (BFR)
Description: All participants completed high-intensity interval exercise plus (1) BFR applied during exercise phase, or (2) BFR applied during interval phase, or (3) no BFR applied.
Study NCT04854356 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise with blood flow restriction (BFR)
Description: All participants completed high-intensity interval exercise plus (1) BFR applied during exercise phase, or (2) BFR applied during interval phase, or (3) no BFR applied.
Study NCT05307302 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Seated Medicine Ball Throw
Description: A measure of upper limb physical performance, using 2-kg medicine ball and a standardized protocol, throwing distance expressed in meters.
Study NCT05307302 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Closed Kinetic Chain Upper Extremity Stability Test
Description: A measure of upper limb physical performance, using body weight and a standardized protocol, touches between hands expressed in number of touches.
Study NCT05307302 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Passing Accuracy
Description: A measure of the basketball passing skills, passing of The American Alliance for Health, Physical Education, Recreation and Dance (AAHPERD) test battery will be used in a standardized protocol. Accurate passes will be expressed in points.
Study NCT05787925 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical corticosteroid
Description: 26 patients will administrate topical corticosteroid: triamcinolone acetonide 1% oral gel Kenacort-A Orabase three times daily for 8 week that will be applied after meals and at night with avoidance of foods and drinks for 30 minutes after the application
Study NCT06454578 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adebrelimab + Apatinib
Description: the first 6 months or 8 cycles: Adebrelimab 1200 mg, every 3 weeks； Apatinib 250 mg/day~Maintenance phase： Adebrelimab 1200 mg, every 3 weeks, Maximum maintenance up to 2 years
Study NCT05658133 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Survey of sports nutrition knowledge
Description: Questionnaire
Study NCT05707702 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Probiotic oral lozenges
Description: Participants in this arm will be be instructed to take a lozenge daily for 6 weeks. They will also receive oral dysplasia standard of care.
Study NCT05707702 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care for oral dysplasia
Description: Oral dysplasia standard of care includes clinical surveillance and risk factor reduction (such as smoking cessation).
Study NCT05386706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Digital Intervention
Description: This study developed a mini-program that combined diet, exercise, sleep, and mood interventions for PCOS women.
Study NCT05386706 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Traditional metformin monotherapy.
Study NCT06165133 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mesh inguinal hernia repair performed by Non-Surgeon Physicians (NSP)
Description: Mesh inguinal hernia repair performed by Non-Surgeon Physicians (NSP) through an accredited training programme prior to commencing participation in the study
Study NCT04844268 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cohort 1 VACCINE RNA MCTI CIMATEC HDT (HDT-301) vaccine
Description: Intramuscular injections of 1 µg of novel Lipid-Inorganic Nanoparticle (LION) formulated replicating RNA-based vaccine (VACCINE RNA MCTI CIMATEC HDT (HDT-301)) at a dose of 1 µg on days 1 and 28 (group 1) or 1 and 56 (group 2), or a schedule of single dose administration (group 3).
Study NCT04844268 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cohort 2 RNA VACCINE MCTI CIMATEC HDT(HDT-301) vaccine
Description: Intramuscular injections of 5 µg of novel Lipid-Inorganic Nanoparticle (LION) formulated replicating RNA-based vaccine (VACCINE RNA MCTI CIMATEC HDT(HDT-301)) at a dose of 5 µg on days 1 and 28 (group 1) or 1 and 56 (group 2), or a schedule of single dose administration (group 3).
Study NCT04844268 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cohort 3 VACCINE RNA MCTI CIMATEC HDT(HDT-301) vaccine
Description: Intramuscular injections of 25 µg of novel Lipid-Inorganic Nanoparticle (LION) formulated replicating RNA-based vaccine (VACCINE RNA MCTI CIMATEC HDT(HDT-301)) at a dose of 25 µg on days 1 and 28 (group 1) or 1 and 56 (group 2), or a schedule of single dose administration (group 3).
Study NCT04844268 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Intramuscular (IM) injection of saline (0.9% sodium chloride) on days 1 and 28 (group 1) or 1 and 56 (group 2), or a schedule of single dose administration (group 3), in each cohort.
Study NCT06165133 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Mesh inguinal hernia repair performed by fully trained surgeons
Description: Mesh inguinal hernia repair performed by fully trained surgeons, recognised by the Ghana College of Surgeons and Physicians and other recognised Surgical Colleges around the globe.
Study NCT04844268 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intramuscular (IM) injection of saline (0.9% sodium chloride) on days 1 and 28 (group 1) or 1 and 56 (group 2), or a schedule of single dose administration (group 3), in each cohort.
Study NCT05512416 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dalpiciclib plus letrozole
Description: Six 4-week cycles of dalpiciclib orally, 150mg, day 1-21, and letrozole orally, 2.5 mg, day 1-28
Study NCT04871958 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Continuous glucose monitoring (CGM, Dexcom G6)
Description: The Dexcom G6 sensor will be placed on the back of the upper arm at admission and changed after 10 days. In the participants randomized to Real-time CGM, glucose values will be transmitted through Bluetooth to a mobile phone at the bedside. From this phone data are transmitted to a tablet in the nursing station.~In the blinded CGM group, sensor readings will be blinded to patient and healthcare providers.~The MDI groups will be managed with basal/bolus insulin regimen, as clinically indicated.~V-Go will be placed on the abdomen each morning. Insulin-naïve patients randomized to the V-Go system will start at the lowest basal rate (20 UI/24h).~On daily basis, expert diabetologists will retrospectively review CGM data and provide indications for insulin therapy adjustments.
Study NCT05011669 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lurasidone
Description: Oral administration with a meal or within 30 min after eating in the evening. The dosage could be adjusted from Day 8.
Study NCT04797364 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pharmacogenetic Testing
Description: Participants will donate a 2ml (teaspoon) sample of saliva. DNA extracted from the saliva sample will be used for genotyping. Genotyping results will be translated into an interpretative clinical report using evidence-based software (Sequence2Script) developed by our group and delivered to the treating physician for use in their clinical decision-making. The report will contain genotyping results, predicted phenotype, and evidence-based drug selection and dosing recommendations relevant to the child's current and future care
Study NCT05962658 — intervention group
Intervention type: OTHER
Intervention: qEEG
Description: qEEG data was collected with patients and healthy individuals in resting eyes-closed: the relative spectral power of the frequency bands delta, theta, alpha and beta was evaluated.
Study NCT06056076 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mini Squats Training
Description: Mini Squats at a rate of ten squats at minimum range around 10-15 degrees at start along with Interferential Therapy for 10 minutes.
Study NCT06056076 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Endurance Training
Description: Endurance training by the use of medium resistance therapeutic band at start along with Interferential Therapy for 10 minutes.
Study NCT06122038 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Tart Cherry Extract Powder
Description: Tart Cherry Extract Powder (NordicCherry, SpecNova, LLC). Dispensed during visit 1. Participants will consume 1 dose per day for 10 days.