AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05676216 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Bicarbonate
Description: Sodium bicarbonate 66.4 mEq in 100 mL normal saline intravenous dripping when vertigo patients visit Emergency Department
Study NCT05445765 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: anti-CD33 CAR T cells
Description: Anti-CD33 CAR T cells are used to treat patients. Patient will be administered either fresh or thawed CAR T cells by IV injection after receiving lymphodepleting chemotherapy.
Study NCT05836207 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Abstinence-focused Contingency Management (CM) - stand alone
Description: Outpatient abstinence-focused contingency management (CM) as stand-alone treatment (12 weeks). Monetary incentives (vouchers) are provided for cannabis abstinence, based on twice-weekly rapid test urinalysis and an escalating reward scheme with bonuses. Urine samples are collected at the treatment centre during 15-minute sessions by a trained CM-practitioner. For each cannabis-negative urine, patients receive a monetary voucher starting at €5 and escalating to max. €35 after eight consecutive weeks of cannabis abstinence, with an additional €10 bonus after two consecutive cannabis-negative urines. The voucher-value is reset to €5 after a cannabis-positive urine test. Total earnings can be max. €675 for 12 weeks of consecutive cannabis abstinence (average: €8 p/day). Youths sign an agreement stating that vouchers must be spent on recovery-oriented goals.
Study NCT05836207 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Outpatient Cognitive Behavioural Therapy (CBT)
Description: CBT is the usual care first line treatment for CUD in youth, in the Netherlands. CBT for CUD is focused on learning cognitive, emotional, motivational and behavioral skills to reduce or cease cannabis use, and generally consists of 12 once-weekly 60-minute sessions and 'homework' exercise assignments, provided by a psychologist.~Youths receive 12 weeks of outpatient usual care CBT consisting of once-weekly 60-minute sessions according to the standard CBT youth protocol by a trained psychologist. CBT-youths receive the same cannabis urine-testing procedures as CM-youths, but test results will not be disclosed to treatment staff or patient, and no rewards will be given for cannabis abstinence.
Study NCT05431426 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CH6001
Description: CHF6001 will be administered using the NEXThaler® DPI device
Study NCT04811170 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Counselling
Description: Participants with mild to moderate mood symptoms will receive a maximum of 6 counselling sessions and will be assessed at baseline (T0, W1), at post-treatment for counselling group (T1, W8), and after 2 booster sessions. Participants in the waiting list control group will receive the same counselling service after the counselling group completed the intervention. Participants with severe mood symptoms will receive a maximum of 10 counselling sessions and will be assessed at baseline (T0, W1), at post-treatment for counselling group (T1, W12), and after 2 booster sessions. Participants in the waiting list control group will receive the same counselling service after the counselling group completed the intervention.
Study NCT04811170 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Counselling
Description: Participants with mild to moderate mood symptoms will receive a maximum of 6 counselling sessions and will be assessed at baseline (T0, W1), at post-treatment for counselling group (T1, W8), and after 2 booster sessions. Participants in the waiting list control group will receive the same counselling service after the counselling group completed the intervention. Participants with severe mood symptoms will receive a maximum of 10 counselling sessions and will be assessed at baseline (T0, W1), at post-treatment for counselling group (T1, W12), and after 2 booster sessions. Participants in the waiting list control group will receive the same counselling service after the counselling group completed the intervention.
Study NCT05676216 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diphenhydramine + Sodium Bicarbonate
Description: Diphenhydramine 30 mg in 100 mL normal saline intravenous dripping with Sodium bicarbonate 66.4 mEq intravenous push when vertigo patients visit Emergency Department
Study NCT05978063 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: difelikefalin 0.25 mg tablets
Description: Oral difelikefalin 0.25 mg administered twice daily
Study NCT05978063 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo tablets
Description: Oral Placebo administered twice daily
Study NCT04470362 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Isokinetic dynamometer
Description: an isokinetic strengthening program for the quadriceps muscles. Twenty-four strengthening session will be performed using an isokinetic device. The exercise program begins with 60% of the mean peak torque, and the patient reaches this intensity by auditory biofeedback. An increasing dose program will be used in the first 5 sessions (1 set to 5 sets), and a dose of 6 sets will be applied from the sixth to twenty-fourth sessions, with the density rising from 60% to 80% of the mean peak torque according to the patient tolerance. Each set consisted of 5 repetitions of concentric (Con/Ecc) contraction in angular velocities of 30°/second and 120°/second for extensors. This program accomplished significant results in increasing the quadriceps power and strength.
Study NCT04470362 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Isokinetic dynamometer
Description: an isokinetic strengthening program for the quadriceps muscles. Twenty-four strengthening session will be performed using an isokinetic device. The exercise program begins with 60% of the mean peak torque, and the patient reaches this intensity by auditory biofeedback. An increasing dose program will be used in the first 5 sessions (1 set to 5 sets), and a dose of 6 sets will be applied from the sixth to twenty-fourth sessions, with the density rising from 60% to 80% of the mean peak torque according to the patient tolerance. Each set consisted of 5 repetitions of concentric (Con/Ecc) contraction in angular velocities of 30°/second and 120°/second for extensors. This program accomplished significant results in increasing the quadriceps power and strength.
Study NCT05473117 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary Magnetic Resonance Angiography (CMRA)
Description: A highly optimised CMRA protocol integrating advanced, automated software for detection of coronary artery stenosis
Study NCT06259240 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Prone plank exercises
Description: Patients in this group will recieve prone plank exercises, three times a week, for eight weeks, and with a moderate hard intensity. During the first four weeks, the exercises session began with light walking for five minutes followed by corrected exercises. Firstly, women will perform stable prone plank exercises. Secondly, women will be asked to apply the unilateral position of prone plank. Thirdly, using a 65 cm diameter Swiss ball, women will be asked to assume the prone bridge position. During the last four weeks, women will be asked to repeat the same program noting that the progressive prone plank exercises should be applied in a dosage of 20 repetitions, three sets, holding the contraction for one minute, and taking a break for two minutes.
Study NCT06259240 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Electrical Stimulation
Description: Electrical Stimulation
Study NCT05145244 — intervention group
Intervention type: OTHER
Intervention: NO intervention
Description: No intervention
Study NCT04029298 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Lifestyle Interventions
Description: Educational based intervention to enhance lifestyle modifications such as diet, exercise, patient activation, and medication adherence
Study NCT04029298 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle Interventions
Description: Educational based intervention to enhance lifestyle modifications such as diet, exercise, patient activation, and medication adherence
Study NCT06019377 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Stronger Youth Networks and Coping (SYNC)
Description: SYNC is a 10-module online curriculum adapted from evidence-based cognitive change methods, including Coping Effectiveness Training (CET), co-facilitated by service providers in Independent Living Programs (ILPs; federally-funded transition skill-building services accessed by most foster youth in the US) and near-peers (have lived experience in foster care). SYNC aims to increase youth capacity to appraise stress and regulate emotional responses, to flexibly select adaptive coping strategies, and to specifically promote informal and formal help-seeking as an effective coping strategy.
Study NCT06050785 — intervention group
Intervention type: DRUG
Intervention: Vancomycin
Description: ACL graft will be soaked in vancomycin versus gentamycin
Study NCT05949827 — intervention group
Intervention type: DEVICE
Intervention: Dynamic Light Therapy Device, LSA-1
Description: Dynamic Light Therapy
Study NCT05949827 — intervention group
Intervention type: DEVICE
Intervention: Dynamic Light Therapy Device, LSA-2
Description: Dynamic Light Therapy
Study NCT05949827 — intervention group
Intervention type: DEVICE
Intervention: Dynamic Light Therapy Device, LSA-3
Description: Dynamic Light Therapy
Study NCT05028270 — intervention group
Intervention type: PROCEDURE
Intervention: Balloon technology;Microcatheter technology
Description: Describe each group's intervention in sufficient detail, including how and when to give the intervention Suspend or modify the criteria for interventions that have been assigned to the subject (such as changing the dose of the drug due to hazards or subject requirements or improvement/deterioration of the condition, etc.) Strategies to improve the compliance of intervention programs, and other measures to monitor compliance (such as the return of drug tablets, laboratory inspections, etc.) Related care and interventions allowed or prohibited during the trial
Study NCT05647785 — intervention group
Intervention type: DEVICE
Intervention: Long-term follow-up of cerena™
Description: Long term follow-up for eligible participants from the RESTORE study
Study NCT05647785 — intervention group
Intervention type: DEVICE
Intervention: Long-term follow-up of attune™
Description: Long term follow-up for eligible participants from the RESTORE study
Study NCT06218290 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxylanthanum Carbonate
Description: Phosphate Binder to Reduce Hyperphosphatemia
Study NCT05551195 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: WB001
Description: WB001 is a digital therapeutic for postpartum depression.
Study NCT05551195 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: ED001
Description: ED001 is a digital therapeutic for postpartum depression.
Study NCT05286034 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Decision aid tailored to women with lower educational attainment,accessible via artificial intelligence-based Chatbot platforms
Description: Non-compliant women those that have not been screened for more than 4 years and living in the disadvantaged areas will be sent screening reminder letters to perform HPV self-sampling (HPVss) test, with access to decision aid tailored to women with lower education attainment and available via Chatbot platforms.~ChatBot will deliver information in a responsive, conversational way via text and spoken language in multiple languages through multiple mobile channels.
Study NCT04717154 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: 4 courses of 1mg/kg q3w
Study NCT04717154 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: 4 courses of 3mg/kg q3w, followed by maintenance flat dose (480mg, q4w, for 10 doses)
Study NCT05186220 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cardioneuroablation
Description: After 3D mapping of the surface of the left and right atrium and the superior vena cava (Ensite Navx, Carto), localization of ganglion plexus (GP) will be performed either anatomically and/or by means of high frequency stimulation (HFS). The anterior and superior right sided GP will always be ablated per protocol. Other GP will be ablated according to interventional electrophysiologist judgement. The endpoint of the ablation procedure will be 1) absence of a vagal response after HFS from the right jugular vein and 2) an increase in at least 10 bpm as compared to baseline.
Study NCT05186220 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Permanent dual chamber pacemaker implantation
Description: Under local anesthesia and using a subclavian or cephalic vein approach a dual chamber pacemaker implantation with a lead in the right atrium and a lead in the right ventricle will be performed. The device will be programmed in a AAI-DDDR mode to avoid unnecessary ventricular pacing.
Study NCT04783077 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WhatsApp
Description: Participants assigned to the WhatsApp group will receive weekly messages developed by communication specialists aimed to motivate blood donation, be encouraged to discuss their blood donation experiences, and share their own motivations for donating blood in a moderated, closed group over a six-month duration. The moderator will provide guidelines on acceptable use of WhatsApp in the group, including images they can or cannot share. Participants will also receive standard NBSG communications for first-time donors.
Study NCT04783077 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Participants in this group will receive the standard NBSG communications for first-time donors: 1) a thank you phone call and 2) and a reminder phone call two-weeks prior to the second blood donation eligibility. The second blood donation eligibility is four months after the first donation.
Study NCT04783077 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Docudrama
Description: Participants will be exposed to a document-drama related to blood donation.
Study NCT04830488 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: e-learning didactic module
Description: Participants utilize e-learning
Study NCT04830488 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personal reflection activities
Description: Participants complete questionnaires
Study NCT05876273 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Neural-net Artificial Pancreas
Description: NAP is a neural-net implementation of the previously tested UMPC algorithm (below).
Study NCT05876273 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: University of Virginia Model Predictive Control
Description: A previously tested artificial pancreas control algorithm, based on a differential-equation model of the human metabolic system in diabetes.
Study NCT05945160 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Alpha Lipoic Acid 300mg
Description: A naturally occuring mitochondrial antioxidant
Study NCT05945160 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Coenzyme Q10 200mg
Description: A naturally occuring mitochondrial antioxidant
Study NCT05401318 — intervention group
Intervention type: PROCEDURE
Intervention: Tumor tissue sampling for organoid development
Description: Fresh tissue from colorectal tumors will be sampled and cultivated in 3D cultures for drug testing.
Study NCT05032885 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physiotherapy
Description: Patients in the intervention group will receive early physiotherapy treatment. This intervention will consist of exercises and physiotherapy techniques commonly used and aimed at improving the patient's respiratory and motor conditioning.~At the respiratory level: diaphragmatic and costal targeted ventilation, pursed-lip breathing and bronchial hygiene techniques if required.~At the motor level: passive, active-assisted kinesitherapy and analytical and global potentiation of the upper and lower limbs that will allow the maintenance and improvement of the articular pathway and will prevent muscle weakness; retraining of transfers and balance; gait reeducation.
Study NCT04882527 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-invasive brain stimulation
Description: Stimulation will be applied once per subject with one mA for 20 minutes over either the left inferior frontal lobe, the right inferior frontal lobe or the right superior parietal lobe.
Study NCT04882527 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: The electrode positions and the attachment procedures correspond to those of real tDCS but the electrical current will only be ramped up to 1 mA and switched off completely after 30 s of stimulation.
Study NCT06287983 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Inspiratory Muscle Trainer (IMT) (POWERbreathe Medic Classic)
Description: Inspiratory muscle training will be started at an intensity of 50% of the patient's measured PIMAX value and will be increased by 2 cm/H20 per day according to patient tolerance, and will be applied for a total of 6 weeks / 5 days per week / 3 sessions per day / 10 breaths per session.
Study NCT06287983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The Sample Spondylitis Exercise Program
Description: The Sample Spondylitis Exercise Program recommended by the Spondylitis Association of America will be translated into Turkish and each exercise will be applied in 3\*10 sets. The exercise program will be applied to both groups, 3 sessions a week for 60 minutes for 6 weeks.
Study NCT04843228 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Bias Modification
Description: There will be four sessions of CBM. Each session will consist of two different part. The first part of the intervention will be the training based on the ambiguous scenario paradigm for perfectionism developed by Dodd (2019). Participants will need to complete word fragments in the last part of the scenario to resolve the ambiguity of the scenario. Then, a comprehension question will be presented to them to underscore the interpretation condition. Feedback will be given after each question. For the second part of the intervention aimed to intervene intolerance to uncertainty, word sentence association paradigm for intolerance to uncertainty developed by Oglesby (2017) will be used. In this intervention, participants will be asked to judge the relatedness of words and sentences which will be presented to them. Feedback will be given after each word-sentence.
Study NCT04843228 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Cognitive Bias Modification for Control Group
Description: For the first part of the intervention, the control group will be presented with the same procedures as the active group; however, feedbacks will be given to resolve the scenarios in a neutral way. When it comes to the second part of the intervention, different word-sentence pairings will be presented to the control group.
Study NCT05539664 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03
Description: The experimental group used the experimental medical device Hydrogen-Oxygen Generator with Nebulizer(Shanghai Asclepius Meditec Co., Ltd. ) The flow rate was 3L/min, and the cumulative treatment time was not less than 6 hours per day.
Study NCT05539664 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: the hospital routine oxygen supply equipment (wall oxygen or cylinder oxygen)
Description: the hospital routine oxygen supply equipment (wall oxygen or cylinder oxygen). The flow rate was 3L/min, and the cumulative treatment time was not less than 6 hours per day.
Study NCT05411731 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy treatment
Description: The control group (group A) will receive the exercise program which focused on improving the arm function as well as shoulder abduction and external rotation for 10 week.~stretching Aeroplan positioning
Study NCT06017869 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: MNV-201
Description: Autologous CD34+ cells are isolated from the participant's peripheral blood after mobilization by leukapheresis. Allogeneic mitochondria are isolated under aseptic conditions from healthy donor placenta, cryopreserved and qualified before use.
Study NCT05975060 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: XBB.1.5 Vaccine (Booster)
Description: Omicron sub variant XBB.1.5 SARS-CoV-2 rS /Matrix-M Adjuvant the monovalent \[5 μg/50 μg\] NVX-CoV2601) XBB.1.5 Vaccine (Booster)
Study NCT05975060 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: XBB.1.5 Vaccine (single dose)
Description: Omicron sub variant XBB.1.5 SARS-CoV-2 rS /Matrix-M Adjuvant the monovalent \[5 μg/50 μg\] NVX-CoV2601) XBB.1.5 Vaccine ( single dose)
Study NCT06526559 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Barbed suture
Description: Use of two absorbable barbed sutures for each arm in the ureteropelvic anastomosis in minimally invasive dismembered pyeloplasty
Study NCT06526559 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: PGA suture
Description: Use of two absorbable polyglactin sutures for each arm in the ureteropelvic anastomosis in minimally invasive dismembered pyeloplasty
Study NCT06545695 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Erlotinib
Description: Part B will be the dose escalation component, in which the subject will initiate 50 mg erlotinib,8 weeks later escalate to 75 mg, and then 8 weeks later to 100 mg erlotinib pending tolerance after each 8-week period.
Study NCT05727800 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-668
Description: Suspension for oral administration.
Study NCT05727800 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Suspension for oral administration.
Study NCT05727514 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: music composition
Description: 4-session music composition program for participants lead by a composer-mentor, includes optional viewing of online string quartet performances of final musical scores