AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06425705 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo capsule three times a day alongside their standard treatment with renin-angiotensin system inhibitors.
Study NCT06012929 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ONC201
Description: ONC201 is an oral medication given once per week
Study NCT06322407 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate Ganglion Block (SGB)
Description: All SGB procedures will be performed by the same experienced physicians. Patients will be positioned in a supine position with the neck slightly hyperextended and receive a SGB procedure using the B-ultrasound visualization technique (Aurora A5 Ultrasound, Risco Tech Co., Ltd.). 1% lidocaine 5mL (Shanxi Jinxin Shuanghe Pharm Co., Ltd.) will be injected below the prevertebral fascia on the surface of longus colli muscle
Study NCT06322407 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standardized drug treatment
Description: Topiramate(Topiramate, Xi'an Yangsen Pharmaceutical Co., Ltd) will be started at a low dose and then increased gradually until optimally effective, side effects become intolerable, or the maximum recommended dose is reached. During the 4-week up-titration phase, the intention will increase dose weekly in 25 mg increments with the aim of reaching 50-100 mg/day. Ibuprofen((Fenbid, Tianjin Shike Pharmaceutical Co., Ltd)will be chosen as acute treatment, but no more than 10 times per month to avoid medication overuse headache.
Study NCT06322407 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standardized drug treatment
Description: Topiramate(Topiramate, Xi'an Yangsen Pharmaceutical Co., Ltd) will be started at a low dose and then increased gradually until optimally effective, side effects become intolerable, or the maximum recommended dose is reached. During the 4-week up-titration phase, the intention will increase dose weekly in 25 mg increments with the aim of reaching 50-100 mg/day. Ibuprofen((Fenbid, Tianjin Shike Pharmaceutical Co., Ltd)will be chosen as acute treatment, but no more than 10 times per month to avoid medication overuse headache.
Study NCT06441019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HAIC（Oxaliplatin+ Raltitrexed）、TQB2868、Ramucirumab
Description: The patient will receive combined treatment with HAIC, TQB2868, and Ramucirumab. After enrollment, the patient will undergo routine hepatic artery angiography via femoral artery catheterization and placement of a hepatic artery catheter，they will then receive 150ml of 5% sodium bicarbonate + Oxaliplatin (85mg/m2) for 4-6 hours + Raltitrexed (2mg/m2) for 2-4 hours . This will be done every 3-4 weeks for at least 2 cycles. Systemic treatment will be administered every 21 days, with TQB2868 injection given on the first day of each cycle (1-7 days after HAIC). The fixed dose of TQB2868 will be 300mg, and Ramucirumab will be given at a dose of 500mg (initial intravenous infusion for 60 minutes, followed by 30 minutes if tolerated).
Study NCT05012072 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Mastery Lifestyle Intervention
Description: Combination cognitive behavioral intervention of phase 3 CBT using ACT and PST
Study NCT05579366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rina-S
Description: Intravenous infusion of Rina-S
Study NCT06286852 — intervention group
Intervention type: BEHAVIORAL
Intervention: Administration of ChEDE- Child Version of the EatingDisorder Examination
Description: Administration of ChEDE- Child Version of the EatingDisorder Examination
Study NCT05579366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin intravenous infusion
Study NCT05579366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab intravenous infusion
Study NCT05579366 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab intravenous infusion
Study NCT06689774 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Staff Tobacco Quit Line Referral Implementation Support
Description: Salvation Army personnel will receive training and will be engaged in efforts to plan, evaluate, adapt, and sustain tobacco treatment referral as part of the social services they provide to adult Salvation Army service consumers who use tobacco. Implementation support will take the form of ongoing engagement of an outreach specialist with a team of Salvation Army personnel and consumers who lead Quit Line referral efforts in the Salvation Army.
Study NCT06689774 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Consumer Incentives for Immediate Referral to a Tobacco Quit Line
Description: Salvation Army personnel will offer an incentive to adult consumers who use tobacco to encourage immediate acceptance of a live call with the Wisconsin Tobacco Quit Line. The incentive will be designed by Salvation Army personnel to fit the local context and to be sustainable over time, such as extra access to existing support or resources.
Study NCT06687135 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: KOKU
Description: KOKU is a digital strength and balance programme designed to prevent physical decline and frailty KOKU provides access to personalised, progressive strength and balance exercises.~More information can be found at: https://kokuhealth.com/
Study NCT05938439 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MAGUS placement
Description: An upper endoscopy will be performed with the use of fluoroscopy under general anaesthesia with orotracheal intubation. The delivery system will be placed over a guidewire, under fluoroscopy. The main steps are the following:~* Placement through the endoscope of a soft guidewire through the upper GI tract;~* Insertion of the MAGUS system on the guidewire;~* Advancement of the MAGUS system until proximal magnet reach the top of the septum;~* Release and placement of the proximal magnet at the bottom of the septum, pouch side;~* Meeting of the distal and proximal magnet on both sides of the septum, by pulling on the delivery system;~* Release of the distal magnet and activate the retractable wire;~* Insure that wire is not blocked and unblocked it if applicable.~Endoscopy and contrast injection will be performed before and after placement to ensure the correct positioning of the magnets.
Study NCT06687135 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: FaME / OTAGO leaflet and AGE UK Stay Steady Leaflet
Description: A leaflet with information on a combination of strength and balance exercises and walking programs, performed on a weekly basis by older adults at home, or community settings. The exercises can be done individually or in a group setting and are aimed at reducing falls in older adults.~More information can be found at: https://fameexercise.com/ and https://www.livestronger.org.nz/assets/Uploads/acc1162-otago-exercise-manual.pdf https://www.ageuk.org.uk/information-advice/health-wellbeing/exercise/staying-steady-download-page/#:\~:text=This%20guide%20outlines%20things%20you%20can
Study NCT06689657 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive behavioral group therapy for adolescents and non violent resistance group for parents
Description: In the adolescents group, this cognitive-behavioral group therapy will include emotion regulation skills, distress tolerance skills, cognitive strategies, work on values and problem-solving strategies~Those sessions will include psychoeducation about adolescents, about suicidal ideation and suicidal behavior, coping with adolescent emotional distress, support on how to be a parent today (screen regulation...) and manage daily life
Study NCT05866822 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: APA
Description: 24 APA sessions
Study NCT05866822 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: APA
Description: 24 APA sessions
Study NCT05866822 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PAE
Description: 8 individuals sessions of PAE
Study NCT06689657 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Adolescent group therapy (CARES) and parent group therapy (RNV)
Description: In the adolescent group, they will attend 8 group sessions during 1 month (2 sessions/week). There also will be a boost session 3 month after the last session. Parents will attend 4 group sessions during 1 month too (1 session/week). There will be 2 boost sessions : 1 month and 3 month after the last session Patients will be randomized in each group with blinded assessment
Study NCT06686082 — intervention group
Intervention type: DRUG
Intervention: Biologics
Description: The ultrasonic changes of synovitis and enthesitis were observed after 12 weeks of treatment with biologic agents
Study NCT06691074 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Catheter ablation of cavotricuspid isthmus using flower configuration of the Farapulse catheter
Description: catheter ablation
Study NCT06691074 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Catheter ablation of cavotricuspid isthmus using basket configuration of the Farapulse catheter
Description: Catheter ablation of cavotricuspid isthmus using basket configuration of the Farapulse catheter
Study NCT06695520 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caudal epidural block
Description: Ultrasound Guidance: Using ultrasound improves the accuracy of the block by allowing real-time visualization of the anatomy and needle placement . injection: .5-1mg/kg of 25% bupivacaine according to the needed block level.
Study NCT06695455 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Swallowing rehabilitation by rhythmic auditory cue
Description: Three assessments, each spread over two days, will be administered at three different time points during the study: before the experiment (T0), after 7 weeks of the experiment (T1), and 3 months after the intervention (T2). The evaluation will include a pharyngography as well as a clinical assessment of swallowing and rhythmic abilities.~Each subject will be invited to participate in 3 individual rehabilitation sessions per week for 7 weeks, conducted by a speech therapist at La Musse Hospital. Each session will be structured similarly: the subject will be asked to swallow their saliva, followed by a nectar-like texture (IDDSI 2) and a pudding-like texture (IDDSI 4), timed to the rhythm of a metronome. The rhythm will vary throughout the sessions. The goal will be to get as close as possible to the rhythm of a healthy swallow.
Study NCT06695221 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Traditional Kefir
Description: 350 mL/day of traditional fermented/prepared kefir
Study NCT06695221 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Milk (placebo)
Description: 350 mL/day of commercial 2% fat milk
Study NCT06688292 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Taneasy 600mg granules
Description: Treatment of respiratory affections characterized by thick and viscous hypersecretion due to acute bronchitis,chronic bronchitis and its exacerbation, plumonary emphysema,mucoviscidosis and bronchiectasis.
Study NCT06688292 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Actein effervescent 600mg
Description: Treatment of respiratory affections characterized by thick and viscous hypersecretion due to acute bronchitis,chronic bronchitis and its exacerbation, pulmonary emphysema, mucoviscidosis and bronchiectasis.
Study NCT06689904 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nanodropper
Description: One eye is randomly selected to be dilated with the nanodropper
Study NCT06689904 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard eye drop bottle
Description: eye is dilated with the standard eye drop bottle
Study NCT06690073 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Relearning Program
Description: Total duration of the intervention is 45 minutes per session (30 minutes of CPT treatment followed by 15 minutes MRP), three sessions per week.~MRP of sitting and standing activities: The physical therapist will instruct the participant, who will be seated in an armrest-equipped chair, to keep their feet back and position their trunk forward.. The participant will then be guided to press down through the affected foot, stand up quickly, and move their hips forward. The therapist will suggest pressing down through the participant's knee along the leg while moving it forward through the affected foot.~MRP of standing to sitting: The participant will stand while the physiotherapist assists with anterior shoulder movement and knee bending at the start of the transition. The therapist will then help maintain weight on the affected leg while sitting. The participant will progress by standing and sitting at different seat heights, stopping at various points in the ROM, and changing speed.
Study NCT06690073 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Physical Therapy
Description: Conventional Physical Therapy (CPT) will be administered to the control group three times per week for six weeks (45 minutes per session). CPT treatments such as mat activities, assisted movements, weight-bearing strategies, and gymnasium training will be given to the control group.
Study NCT06686251 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App LuAna
Description: Inclusion of chest x-ray images in the LuAna app to receive feedback on lung findings.
Study NCT06688019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: conventional oxygenation (nasal cannula)
Description: conventional oxygenation arm will receive oxygen at 2 L/min via nasal cannula, while Optiflow THRIVE arm will receive oxygen at 50 L/min via Optiflow THRIVE during the procedure.
Study NCT06688019 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: high-flow humidified oxygen-delivery system (OptiFlow THRIVE)
Description: conventional oxygenation arm will receive oxygen at 2 L/min via nasal cannula, while Optiflow THRIVE arm will receive oxygen at 50 L/min via Optiflow THRIVE during the procedure.
Study NCT06687018 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kaltenborn mobilisation
Description: Kaltenborn mobilisation Grade 3 along with common treatment for 3 minutes, repeated 3 sets with rest of 1 minutes, three sessions per week for four weeks. Conventional treatment comprises a hot pack for 10 minutes, SWD for 5 minutes, and nerve and tendon gliding exercises.
Study NCT06687018 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mulligan mobilisation
Description: Mulligan mobilisation with 10 repetitions with 3 sets and three sessions per week for four weeks. Conventional treatment comprises a hot pack for 10 minutes, SWD for 5 minutes, and nerve and tendon gliding exercises
Study NCT06690749 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Negative pressure therapy, NPT
Description: We designed the experiment based on current clinical cases involving negative pressure therapy (NPT) for wounds and related animal studies. In this study, we applied three levels of negative pressure: -105 mmHg, -125 mmHg, and -145 mmHg, each for 10 minutes.~The -125 mmHg dosage was chosen based on findings from a previous study. Similar studies that utilized increments and decrements of 20 mmHg informed our research.~Moreover, to prevent any damage to new capillaries, we established a base dosage of -125 mmHg and refrained from using negative pressure levels exceeding -150 mmHg.
Study NCT06691087 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Influence of the parameters of the sound timbre on the perception of a sound
Description: The experiment consists of evaluating the sound level of n complex stimuli, then equalising them in loudness, in order to measure a loudness curve in function of timbre descriptors.~The stimuli will then be listened to again in pairs. The task is there to compare the stimuli using a VAS to indicate how different the two sounds are.
Study NCT06691087 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Influence of the parameters of the sound timbre on the perception of a sound
Description: The experiment consists of evaluating the sound level of n complex stimuli, then equalising them in loudness, in order to measure a loudness curve in function of timbre descriptors.~The stimuli will then be listened to again in pairs. The task is there to compare the stimuli using a VAS to indicate how different the two sounds are.
Study NCT06691087 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Complex sound scene comprehension test
Description: The experiment consists in identifying the parameters of the sound timbre that most disturb the understanding of complex sound scenes, by asking the participants to identify sounds whose timbre has been modified.
Study NCT06691087 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Complex sound scene comprehension test
Description: The experiment consists in identifying the parameters of the sound timbre that most disturb the understanding of complex sound scenes, by asking the participants to identify sounds whose timbre has been modified.
Study NCT06691087 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Complex sound scene comprehension test with hearing aids
Description: The experiment will be identical to intervention 2. This time, the modification of the stimulus timbres will focus on the most problematic dimensional modifications, i.e. those where the difference between normal-hearing and hearing-impaired listeners is greatest. We will then modify the signal processing parameters of the hearing aid simulator (for example, the size of the averaging window or the gain balance of the filters), to observe their impact on the salience of certain stimuli.
Study NCT06689150 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Drospinetta
Description: To evaluate the three different types of POPs, the new POPs Drosperinon 4 mg, Desogestrel 75 pg, and Levonorgestrel 30 pg in healthy female subjects as regard to the contraceptive efficacy, bleeding pattern, acceptability and safety
Study NCT06691711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ASPIRE support package
Description: The ASPIRE support package has a modular structure with core modules that all participating families are encouraged to complete initially, followed by optional modules which the family is supported to select from according to their strengths and needs. Core modules provide psychoeducation for the caregiver and optional modules contain information on the selected positive psychology topic together with instructions for suggested activities to be completed by the caregiver with their child to implement evidence-based positive psychology strategies. All resources can be accessed both electronically via an online portal or via the printed resource pack. Each caregiver is supported through the programme by a trained practitioner who offers regular support sessions (up to 8 in total) to provide information, advice and encouragement. Support sessions can take place face-to-face, by video call or over the phone according to participant preference.
Study NCT06688305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga-NI-FAPI
Description: Intravenous injection of one dosage of 111-148 MBq (3-4 mCi) 68Ga-NI-FAPI.
Study NCT06686069 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: bioarginina zero
Description: treatment
Study NCT06686069 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: bioarginina zero
Description: treatment
Study NCT06686069 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: absence of treatment
Study NCT06686069 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: absence of treatment
Study NCT05978128 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Health Education
Description: Access electronic patient portal with educational material
Study NCT05978128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Health Promotion and Education
Description: Receive materials on breast/lung cancer screening
Study NCT05978128 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Navigation
Description: Interact with a patient navigator
Study NCT05978128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT04211870 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: LED clusters
Description: Each LED board contains six (6) LEDs with a wavelength of 660nm and a duration of seven (7) minutes in each muscle. The treatment was carried out in a total of four (4) sessions, one (1) session per week.
Study NCT05472987 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ventral Hernia Repair
Description: Patients will undergo retromuscular ventral hernia repair
Study NCT05618626 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical exercise and dietary intervention for NAFLD
Description: Investigators will assess the efficiency of the intervention by measuring adherence to physical exercise and nutritional diet.
Study NCT06495554 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Measurement of circulating tumor-DNA
Description: Liquid biopsies will be collected at baseline and prospectively during follow-up to measure circulating tumor-DNA.
Study NCT06495554 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Collection of patient-reported outcomes
Description: Patient-reported outcomes will be collected at baseline and prospectively during follow-up.
Study NCT06495554 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Algorithmically determined telephone interview with a nurse
Description: Dependent on the patient's responses on the patient-reported outcome measures.
Study NCT05228015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IK-930
Description: tablets for oral administration
Study NCT05228015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Osimertinib
Description: tablets for oral administration