AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06612099 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mat Pilates Exercise
Description: Individuals in this group will perform mat pilates exercises under the supervision of a physiotherapist for a period of 8 weeks, consisting of a total of 24 exercise sessions. During the exercise sessions, individuals will undergo a 50-minute mat pilates exercise program. In addition to the mat pilates exercise group, on the days when he does not come to the session, resistance exercises will be taught in the form of 2 sets of 8 repetitions, 60-80% of 1 maximum repetition, according to the guidelines of the American Sports Medicine Association, and will be given as home exercises.
Study NCT06667869 — intervention group
Intervention type: DRUG
Intervention: Sedative
Description: Patients admitted to intensive care units who require sedation and mechanical ventilation for more than 24 hours.
Study NCT06621043 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NTI164
Description: Full-Spectrum Medicinal Cannabis Plant Extract containing 0.08% THC, administered orally starting with a dose of 5 mg/kg, titrated up to 20 mg/kg based on tolerance, followed by a maintenance phase at the maximum tolerated dose, and concluding with a gradual dose reduction.
Study NCT06617910 — intervention group
Intervention type: RADIATION
Intervention: SBRT by Cyberknife
Description: The patients with sinonasal maliganacy receive curative surgery then receive adjuvant RT by the method of SBRT by Cyberknife.
Study NCT06621381 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Concentrated exposure and response prevention
Description: The intervention consists of: Psychoducation for the patients (1 session, 2-3h in group format), psychoeducation for the legal guardians (1 session, 3h in group format), exposure and response prevention (3-4 sessions, 9-12h over the course of one week, individual format), group reunions for sharing experiences, motivational work and relapse prevention ( 2 sessions, 3h)
Study NCT06618937 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Treatment medication withdrawal strategy
Description: The study aims to compare early biomarkers-guided versus conventional unguided drugs withdrawal strategy.
Study NCT06621433 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: T-PRF with CAF
Description: Blood sample will be obtained from the patient, conveyed into a titanium tube and immediately centrifuged at 2700 rpm for 12 mins at room temperature using fixed angle centrifuge (PRF Process, Tangkula800-1, China). The fibrin clot will be collected and placed in the PRF compression device (PRF GRF box) and condensed to produce a uniform T-PRF membrane which will be inserted over the recession area and covered by the coronally advanced flap.
Study NCT06621433 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SECTG with CAF
Description: Sub epithelial connective tissue graft will be obtained from the donor site (hard palate), placed into recipient site and secured by sutures, then covered by a coronally advanced flap.
Study NCT06618508 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual debridement
Description: Traditional technique which consists of scraping off the irregular epithelium to allow a new layer to form.
Study NCT06618508 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Phototherapeutic keratectomy
Description: New technique which has been increasingly used and which consists of a 193nm excimer laser that breaks molecular bonds between cells on the epithelial surface.
Study NCT06620991 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phentolamine
Description: A loading dose of 1-5 mg IV bolus over 1 minute is given followed by an IV infusion of a rate of 0.1-2 mg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over a volume of 10ml
Study NCT06620991 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Esmolol
Description: A loading dose of 1 mg/kg IV infused over 1 minute is given followed by an IV infusion of 0.15-0.3 mg/kg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over total volume of 10ml
Study NCT06620718 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: coronectomy
Description: The inferior alveolar nerve and buccal nerve were blocked with maxicaine anaesthetic solution (articaine hydrochloride 40 mg, epinephrine hydrochloride 0.006 mg). Incisions were applied uniformly across all patients, and a triangular flap technique was employed. After elevating the flap and exposing the bone, the bone overlying the crown of the tooth was removed using a bone round bur to fully visualize the tooth\&#39;s crown. Once the crown was fully exposed, the crown preparation was initiated at the enamel-dentin junction using a fissure bur. The crown preparation was completed without leaving any sharp edges, and the crown was extracted. Then, the exposed pulp was washed with sterile serum without any further intervention. The surgical area was sutured using 5/0 silk. Analgesic (25 mg of dexketoprofen trometamol twice a day) and antibiotic (125 mg clavulanic acid, 875 mg amoxicilin twice a day) drugs were described.
Study NCT06619353 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood Sample
Description: Patients' blood samples are tested at 1 month, and then annually for 3 years post-intervention to assess residual thrombotic, metabolic, and inflammatory risk.
Study NCT06619353 — intervention group
Intervention type: OTHER
Intervention: DICOM Dataset
Description: Patients' DICOM dataset is evaluated using artificial intelligence-based quantitative coronary analysis to assess a procedural risk.
Study NCT06622993 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychotherapy
Description: The experimental group will receive the SKILLS program, i.e. 10 group psychotherapy sessions.
Study NCT06621303 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Diabetic foot ulcer treatment
Description: The trial is designed to last up to 26 weeks, including a screening period of 1 week, a treatment period of 1 week, and an observation period of 24 weeks. According to the inclusion criteria, 10 diabetic patients with ulcers will be clinically screened, and after signing the informed consent form, they will be assigned a number. Post-injection of OPM cells, wound assessments are conducted weekly, with physical examinations and vital signs (pulse, blood pressure) recorded at weeks 4, 8, 12, 16, 20, and 24. Clinical laboratory tests (routine blood tests, tumor markers, etc.) are performed at week 12. Vascular CTA and immune cell count in wound lavage fluid are conducted at week 24 post-cellular intervention, followed by a final examination at week 24.
Study NCT06621550 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Interval Training
Description: Participants will receive a single session of HIIT, which last for 19 minutes in duration. During the HIIT session, participants will complete 2 minutes stretching warm-up exercise, followed by a video of exercises which will be projected on the screen to facilitate the participants to follow. The exercise in the video involves various combinations of aerobic and core resistance exercise such as squat jump, jump lunge, push up, burpee, mountain climber etc. The exercise involved bodyweight or minimal basic equipment only, the workout to rest ratio is 45 secs: 15 secs. Participants' heart rate will be kept surveillance and to maintain their respective heart rate attained 85% of aged predicted maximal heart rate during the workout period.
Study NCT06622421 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Piezoelectric surgery
Description: Patients enrolled and randomized into one of the two groups will all undergo surgery to remove necrotic bone on an outpatient basis by the same operator with a decade of experience in the treatment of MRONJ. As per clinical routine, a marginal bone resection procedure will be performed using rotary instruments or piezoelectric instruments (depending on the assignment to one of the two groups). Both surgical procedures involve complete closure of the wound by primary intention using sutures
Study NCT06622421 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Conventional surgery
Description: Patients enrolled and randomized into one of the two groups will all undergo surgery to remove necrotic bone on an outpatient basis by the same operator with a decade of experience in the treatment of MRONJ. As per clinical routine, a marginal bone resection procedure will be performed using rotary instruments or piezoelectric instruments (depending on the assignment to one of the two groups). Both surgical procedures involve complete closure of the wound by primary intention using sutures
Study NCT06622915 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Tissue Doppler imaging and Conventional Echocardiography
Description: non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
Study NCT06618768 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Consumption of an aronia-mixture to prevent Urinary Tract Infections in female patients
Description: The present pilot study will assess the feasibility of methods and procedures to be used in a larger study and contribute to establish power calculations required to conduct a randomised clinical trial which will examine whether consumption of 1 dL aronia-mixture/day for six months will reduce prevalence of symptomativ UTi episodes among adult women with a recent history of uncomplicated, recurrent UTIs.
Study NCT05248113 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electrical stimulation of cochlear nerve
Description: Intraoperative electrical stimulation of the cochlear nerve in patients undergoing surgery for resection of vestibular schwannoma. Activation of the auditory system monitored with scalp recording of auditory brainstem response.
Study NCT06665880 — intervention group
Intervention type: OTHER
Intervention: Routine clinical treatment
Description: Routine clinical treatment is based on the latest international guidelines for DRE.
Study NCT06393257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oscillation and Lung Expansion
Description: A novel airway clearance technology
Study NCT06393257 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Postural drainage
Description: A type of physical therapy used to treat respiratory diseases by changing the patient's body position so that sputum is drained down the respiratory tract so that it can be more easily expelled from the body.
Study NCT06393257 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-infective therapy
Description: Antibiotics were used in these patients.
Study NCT06393257 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Anti-infective therapy
Description: Antibiotics were used in these patients.
Study NCT06393257 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mucolytic
Description: Mucolytics were used in these patients.
Study NCT06393257 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mucolytic
Description: Mucolytics were used in these patients.
Study NCT05172869 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suprainguinal Performed FICB
Description: Linear ultrasound probe places above inguinal ligament sagittally, close to the femoral crease and superior-lateral to the femoral artery. It is aimed to spreading local anesthetics under the fascia iliaca medial-laterally
Study NCT05172869 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Infrainguinal Performed FICB
Description: Linear ultrasound probe places below inguinal ligament transversally, close to the femoral crease and lateral to the femoral artery. It is aimed to spreading local anesthetics under the fascia iliaca medial-laterally
Study NCT06413056 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Micafungin
Description: Preterm neonate with fungal infection provened by fungal culture and who received fluconazole for at least one week will be divided into two groups. Will receive either micafungin or amphotericin B
Study NCT06413056 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amphotericin B
Description: Preterm neonate with fungal infection provened by fungal culture and who received fluconazole for at least one week will be divided into two groups.
Study NCT05883774 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive Transcranial Magnetic Stimulation
Description: rTMS is applied using a transcranial magnetic stimulator with a figure-of-8 coil once per day for 10 consecutive days. rTMS is delivered to the right dorsolateral prefrontal cortex (DLPFC) at a frequency of 1 Hz for 20 minutes (1200 total pulses).
Study NCT05883774 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Repetitive Transcranial Magnetic Stimulation
Description: Sham-rTMS is performed in the same way as the treatment group except that the coil is rotated 90° away from the scalp.
Study NCT04181515 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo oral tablet
Description: placebo stressor
Study NCT04181515 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo oral tablet
Description: placebo stressor
Study NCT04181515 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Yohimbine + Hydrocortisone
Description: Yohimbine 54mg + Hydrocortisone 20mg
Study NCT04181515 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham rTMS
Description: sham rTMS (inactive coil)
Study NCT04181515 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: sham rTMS
Description: sham rTMS (inactive coil)
Study NCT04181515 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active rTMS
Description: active rTMS (10 Hz dlPFC stimulation in group 1; 1 Hz mPFC stimulation in group 2)
Study NCT04561011 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-delivered Cognitive Behavioural Therapy(ICBT)
Description: ICBT provides online structured self-help modules over several months based on the principles of CBT in combination with weekly guidance through emails and telephone calls. The course comprises 6 online lessons that provide psychoeducation about: 1) symptom identification and the cognitive behavioural model; 2) thought monitoring and challenging; 3) de-arousal strategies and pleasant activity scheduling; 4) graduated exposure/pacing; 5) memory and attention; and 6) relapse prevention. Participants will also have the opportunity to ask any questions regarding the content of the program materials and will receive a response from their Guide within 48-72 hours. Guide will spend \~15 mins. per week/per participant. All Guides have completed a university program (psychology or social work) and are registered clinicians or students working under supervision of a registered clinician.
Study NCT04707131 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LEM-S401
Description: siRNA encapsulated in DegradaBALL®
Study NCT04707131 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT04874376 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IOL implantation experimental (Isopure 1.2.3.)
Description: Implantation of Premium Monofocal Isopure 12.3 with retrospective data collection
Study NCT05540093 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: high power pain threshold ultrasound
Description: After explaining the procedure, and the trigger points will be marked by a physical therapist that . Then, the hand placed next to the prone position with the head in the neutral position, and the hands placed next to the body. The frequency was set to 1 MHz, and the intensity increased from 0.5 to 2 until the patient reported an unpleasant sensation. The probe will be held there for 4 s; then, the intensity was reduced by 50%, and the probe was moved over and around the trigger point. This process is done several times for three minutes.
Study NCT05540093 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional therapy
Description: the patients will receive traditional therapy in the form of postural correction exercise, active range of motion and stretching exercise for cervical muscles
Study NCT05540093 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional therapy
Description: the patients will receive traditional therapy in the form of postural correction exercise, active range of motion and stretching exercise for cervical muscles
Study NCT05036889 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Mind.Px Report
Description: Use of Mind.Px report as a reference for potential better matching of biologics to patients.
Study NCT04967625 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: A humanized anti-PD-1 monoclonal antibody
Study NCT04967625 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anlotinib hydrochloride
Description: A tyrosine kinase inhibitor selectively targeting VEGFR-2
Study NCT04310943 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: Tislelizumab, 200mg, Q3W ,use until disease progression
Study NCT05123092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound guided lumbar erectae spinae block
Description: One group by using ultrasound for making erectae spinae block
Study NCT05123092 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intrathecal Morphine injection
Description: Injecting intrathecal morphine
Study NCT05426382 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A digital care solution for patients with NAFLD
Description: A digital solution that provides remote symptom monitoring and support of healthy lifestyle choices through tasks that are made more attractive with gamification and rewards.
Study NCT06495255 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Human Milk Oligosaccharides (HMOs)
Description: HMOs will be applied as a neutral-flavoured powder
Study NCT06495255 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Control
Description: will be applied as powder
Study NCT06251258 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Facial emotion recognition test with and without eye-tracking and Cognitive Emotion Regulation. Questionnaire (CERQ)
Description: Facial emotion recognition test without eye-tracking (explicit test, without time limit) and facial emotion recognition test with eye tracking (implicit test, with observation of fixation points)
Study NCT06251258 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Facial emotion recognition test with and without eye-tracking and Cognitive Emotion Regulation. Questionnaire (CERQ)
Description: Facial emotion recognition test without eye-tracking (explicit test, without time limit) and facial emotion recognition test with eye tracking (implicit test, with observation of fixation points)
Study NCT05024149 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: infrared thermography (IRT)
Description: The temperature and infrared thermography (IRT) images of the facial acupoints of three groups will be recorded by an infrared thermal-imaging camera.
Study NCT05429437 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Injectable platelet rich fibrin .
Description: i-PRF with maxillary canine retraction that will be performed two times on intervention sides according to a standardized protocol.
Study NCT05429437 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Injectable platelet rich fibrin .
Description: i-PRF that will be performed four times on intervention sides according to a standardized protocol.
Study NCT06289634 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Man-made sounds
Description: Participants will be asked to listen to the assigned sounds (relaxing music) for 30 minutes a day for 15 days.
Study NCT06289634 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Natural sounds
Description: Participants will be asked to listen to the assigned sounds (birds, ocean, wind) for 30 minutes a day for 15 days.
Study NCT04785326 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DMB-3115
Description: 45mg or 90mg dose subcutaneous administration
Study NCT04785326 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DMB-3115
Description: 45mg or 90mg dose subcutaneous administration
Study NCT04785326 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Stelara
Description: 45mg or 90mg dose subcutaneous administration
Study NCT04878016 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: ZKAB001
Description: Patients will receive ZKAB001 5mg/kg administered by IV infusion every 21days，
Study NCT04878016 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients will receive placebo administered by IV infusion every 21days.
Study NCT04878016 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin should be administered after completion of placebo/ZKAB001 by IV infusion over 30-60 minutes to achieve an initial target AUC of 5 mg/mL/min. Carboplatin and etoposide will be used for a total of 4 cycles， followed by placebo/ZKAB001 maintenance therapy.
Study NCT04878016 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Carboplatin
Description: Carboplatin should be administered after completion of placebo/ZKAB001 by IV infusion over 30-60 minutes to achieve an initial target AUC of 5 mg/mL/min. Carboplatin and etoposide will be used for a total of 4 cycles， followed by placebo/ZKAB001 maintenance therapy.