AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05127629 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Wound closure with gelatin sponge
Description: After guided bone regeneration, patient in the control group receive gelatin sponge for wound closure.
Study NCT05127629 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wound closure with collagen matrix
Description: After guided bone regeneration, patient in the control group receive collagen matrix (Mucograft Seal) for wound closure.
Study NCT06109675 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition Education
Description: All mothers in this group will be given 3 nutrition education sessions including detailed informations on Nutrition Therapy in Cystic Fibrosis. In addition to the education sessions, an informational booklet and a high-energy sample recipe booklet will be given.
Study NCT05880186 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Acute caffeine supplementation
Description: To evaluate the influence of the time of the day (i.e., morning vs evening) on the effect of caffeine on maximal fat oxidation in women.
Study NCT05880186 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Acute caffeine supplementation
Description: To evaluate the influence of the time of the day (i.e., morning vs evening) on the effect of caffeine on maximal fat oxidation in women.
Study NCT05519982 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Treatment Education Program (STEP-1)
Description: Video conference instruction on behavioral changes to improve sleep.
Study NCT05519982 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced Usual Care
Description: Video conference instruction on relaxation techniques to improve sleep.
Study NCT05877924 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NBL-020 for Injection
Description: NBL-020 for Injection, Q3W, i.v.
Study NCT05614817 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CBP-201
Description: CBP-201 subcutaneous(SC) injection
Study NCT05614817 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: subcutaneous(SC) injection
Study NCT05309070 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: N-acetyl cysteine
Description: Study group will receive N-acetyl cysteine in unmarked boxes, in a daily dose of 1200 mg during two months
Study NCT05309070 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Control group will receive a placebo, in unmarked boxes, during two months
Study NCT06231589 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sperm Selection
Description: Sperm selection using physiological intracytoplasmic sperm injection (PICSI dish) or magnetic-activated cell sorting (MACS) for selecting sperm with high-quality, better morphology and lower DNA fragmentation.
Study NCT06428968 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 160 units nasal insulin spray
Description: Initially, a series of MRI scans, including high-resolution T1-weighted anatomical images, diffusion tensor imaging, resting-state functional MRI, and arterial spin labeling, will be conducted. Subsequently, 160 units of nasal insulin spray will be administered, followed by a second round of MRI scans after a 30-minute interval, encompassing high-resolution T1-weighted anatomical images, resting-state functional MRI, and arterial spin labeling.
Study NCT05417620 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Media Campaign
Description: PrEP social influence campaign, which will use online approaches to promote PrEP within communities in addition to the standard of care activities. Messaging crafted with community input will be geographically targeted to women, parents/mentors, and male partners on Facebook, Instagram, and Whatsapp, all with the intention to promote PrEP for women at high risk of HIV infection and change community norms and influence around PrEP. A combination of static imagery and brief videos will be used to engage these groups via social media platforms. A Facebook page will be created and maintained that can be accessed by anyone anywhere, but will only be advertised/promoted in the intervention districts.
Study NCT05417620 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PrEP Champions
Description: Within venues served by the FSW and AGYW programs, the team will identify and train 1 venue-based PrEP champion per venue who will receive supplies (e.g. a hat, pin and posters, flyers, IEC material) to wear to promote PrEP, facilitate linkage between women interested in PrEP and the TB HIV Care PrEP programme. PrEP champions will be either peers with experience taking PrEP, venue managers or local influencers (e.g. women running shops next to the mobile serving AGYW) that have repeated contact with the women the programme is intended to serve. The final selection of PrEP champions will be made in consultation with the Community Advisory Groups, venues and by the programme who works closely with each of the sites.
Study NCT05417620 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Community Mobilization
Description: A PrEP community mobilization team (2 peers, including one woman and one man) will be recruited within each ward to promote PrEP. The team will present information about PrEP and the PrEP programme at the ward councilors meeting, at Learning Support Agent meetings with parents/guardians, at local events/fairs, community meetings and through engaging men, women and parents across the community through informal conversations. Teams will be wearing branded material and will focus on presenting factual information and decreasing PrEP stigma. Each team will focus on promoting PrEP within their own ward over the 6-month period.
Study NCT05417620 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard of Care
Description: Full-time peer educators employed by the TB HIV Care programme to engage women, layer PrEP promotion across prevention programs, and implement refer a friend strategies, information, education and communication (IEC) materials, service user testimonials, risk reduction posters to increase young women's perception of risk, working after hours/weekends to reach young women, working with school governing bodies, and door-to-door outreach.
Study NCT05069948 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HeadOn
Description: HeadOn is a web application which takes the participant through a 5-stage CBT programme including: (i) understanding post-concussion symptoms; (ii) sleep after a concussion; (iii) lifestyle habits and exercise; (iv) managing negative thought patterns and (v) returning to baseline. The programme is delivered through a combination of weekly tasks (such as completing symptom diary, setting exercise goals and setting up a sleep time routine), audio/video media and reading material.
Study NCT05183360 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 706321
Description: BI 706321
Study NCT05183360 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT04760808 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Baseline Clinical Examination
Description: Evaluations of Postural control; Subjective postural vertical; Subjective visual vertical; Verticality perception
Study NCT04760808 — intervention group
Intervention type: RADIATION
Intervention: Initial 3T MRI of the Brain and Spine
Description: Non-injected CSF flow MRI
Study NCT04760808 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 6-month Follow-up Clinical Examination
Description: Evaluations of Postural control; Subjective postural vertical; Subjective visual vertical; Verticality perception
Study NCT04760808 — intervention group
Intervention type: RADIATION
Intervention: 6-month Follow-up 3T MRI of the Brain and Spine
Description: Non-injected CSF flow MRI
Study NCT05121272 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: cognitive task
Description: cognitive task
Study NCT05910996 — intervention group
Intervention type: PROCEDURE
Intervention: Conversion from vv-ECMO to va-ECMO
Description: Conversion from vv-ECMO to va-ECMO
Study NCT06094478 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: HI-SPEED Protocol
Description: The HI-SPEED Protocol or Bundle consists of 7 components including 1) stroke screening scales, 2) imaging pathways, 3) telestroke operations, 4) a best practice alert, 5) stroke team communication tool, 6) door-to-needle (thrombolysis) treatment pathway, and 7) a standardized hand-off tool. This protocol will be implemented at each participating health system in clusters of 2 health systems.
Study NCT05932238 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Polyethylene glycol 400 and propylene glycol solution/drops - Preservative Free (PF)
Description: commercially available eye drops
Study NCT05932238 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Polyethylene glycol 400 and propylene glycol solution/drops - Preserved
Description: commercially available eye drops
Study NCT06573879 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eccentric Exercise
Description: It was investigated whether volleyball athlete participants would develop muscle architecture, muscle strength and performance parameters differently from the control group by performing eccentric exercises in addition to their exercise routines.
Study NCT05640193 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Lifileucel (LN-144)
Description: A portion of the patient's tumor is resected and serves as the starting material for manufacturing lifileucel. After preparative NMA-LD, patients are infused with their autologous TIL (lifileucel), followed by a short course of high-dose IL-2.
Study NCT04465344 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Implantation of trifocal IOL, Isatis TF (device under investigation)
Description: Patients will be implanted with study IOL in both eyes
Study NCT04465344 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Implantation of monofocal IOL, Isatis (control device)
Description: Patients will be implanted with Control IOL in both eyes
Study NCT06653361 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Green laser
Description: Green Laser
Study NCT06653361 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Green laser
Description: Green Laser
Study NCT06655662 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: β-globin restored autologous hematopoietic stem cells
Description: Eight transfusion-dependent β-thalassaemia subjects aged 6-35 years will be reinfused with β-globin restored autologous hematopoietic stem cells modified with LentiHBBT87Q
Study NCT06655129 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: intense pulsed light
Description: intense pulsed light (IPL) using the Medical Device Anthelia
Study NCT06655116 — intervention group
Intervention type: BEHAVIORAL
Intervention: Diabetic Foot Education
Description: Patients in the intervention group will be interviewed and their diabetic foot knowledge will be evaluated. During the interview, the individual's knowledge about the definition of diabetic foot, risk factors, symptoms, treatment, complications, care and prevention will be evaluated.~In order to systematically plan, implement and evaluate the training to be used in the intervention, it is aimed to implement androgogical training based on the 'Interpersonal Relations Theory'. In this context, the stages in the theory will be followed as follows.
Study NCT06588946 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketone monoester (KME) supplement
Description: 15g of a KME supplement orally consumed 3x daily for 14 days
Study NCT06588946 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo supplement
Description: 50mL taste-match inert calorie-free placebo drink orally consumed 3x daily for 14 days
Study NCT06590649 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Household-level effects
Description: At 3 months, participants randomized to the PILI 'Āina intervention will receive a 6-month intervention centered around the use of a raised-bed home garden as the means of engaging household members to 1) increase their access to and intake of vegetables, 2) learn culturally relevant ways of preparing/cooking fresh vegetables through hands-on cooking lessons with local experts, and 3) build family cohesion through family bonding activities. Participants will be given all the equipment and materials (e.g., soil, seeds, instructions, setup of equipment) needed to grow their vegetables using their raised-bed home garden box throughout the entire study. They will receive seeds for the vegetables that can grow in a relatively short period (i.e., within 6 weeks). The household participants will be analyzed side by side with the index participants.
Study NCT06603792 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EEG-neurofeedback
Description: Traditional neurofeedback uses one or two electrodes to modulate activity within a specific frequency band. Standardized Weighted Low Resolution Electromagnetic Tomography (swLORETA) analyzes the 3D distribution of intracortical brain electrical activity based on surface EEG recordings, enabling real-time brainwave imaging with a spatial resolution under one cubic centimeter. This divides the brain into over 12,000 voxels, offering localization similar to fMRI while maintaining EEG's faster temporal resolution. Source-localized NF can target specific, deeper brain regions, multiple Brodmann areas simultaneously, and provide feedback on connectivity between neural sources, enabling the training of specific neural networks. swLORETA metrics are compared to a normative database of neurotypical brains to produce z-scores for each area and metric. We will use the NeuroGuide normative database, FDA-approved and validated in peer-reviewed studies, widely used in clinical NF.
Study NCT06603792 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: EEG-neurofeedback
Description: Traditional neurofeedback uses one or two electrodes to modulate activity within a specific frequency band. Standardized Weighted Low Resolution Electromagnetic Tomography (swLORETA) analyzes the 3D distribution of intracortical brain electrical activity based on surface EEG recordings, enabling real-time brainwave imaging with a spatial resolution under one cubic centimeter. This divides the brain into over 12,000 voxels, offering localization similar to fMRI while maintaining EEG's faster temporal resolution. Source-localized NF can target specific, deeper brain regions, multiple Brodmann areas simultaneously, and provide feedback on connectivity between neural sources, enabling the training of specific neural networks. swLORETA metrics are compared to a normative database of neurotypical brains to produce z-scores for each area and metric. We will use the NeuroGuide normative database, FDA-approved and validated in peer-reviewed studies, widely used in clinical NF.
Study NCT06590246 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Armored and GPC3-targeted autologous CAR T-cell
Description: Armored and GPC3-targeted autologous CAR T-cells, single infusion intravenously.
Study NCT06593899 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Radiotherapy
Description: Hypofractionated radiotherapy Preoperative hypofractionated 5x5 Gy radiotherapy (5 consecutive days) prescribed on planned target volume
Study NCT06593899 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 3 cycles of AI
Description: Three courses of doxorubicin and ifosfamide (AI, doxorubicin 75 mg/sqm and ifosfamide 10 g/sqm with prophylactic mesna)
Study NCT06604312 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sacroiliac Joint Manipulation
Description: Sacroiliac manipulation was performed using manual treatment method by lying patients on their sides. First, the patient was positioned firmly on the edge of the examination table, while the restricted sacroiliac joint remains on the upper side. Then, the physician's hand was positioned on the patient's hip, and the flexion was made on the lumbar spine with the movement from the hip to the upper thigh, and the impulse given by the HVLA technique was applied in the anteroinferior direction to the iliac crest and trochanter major.
Study NCT06655688 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Commitment Therapy
Description: Acceptance and Commitment Therapy Based Intervention Program was applied to the intervention group in eight sessions online. Each session will last an average of 60-90 minutes. There will be two sessions for one group per week.
Study NCT06603766 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: IV Magnesium Sulfate
Description: MgSO₄'s mechanism in PPHN includes activating cellular processes, modulating membrane excitability, and acting as a physiological calcium antagonist. It exerts sedative, muscle relaxant, and bronchodilatory properties, while concurrently inducing a state of alkalosis.
Study NCT06603766 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Inhalational magnesium sulfate
Description: It gives us the same mechanism of action as IV MgSO4 with less side effects.
Study NCT06590597 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EDUCATIONAL INTERVENTION FOR MALARIA PREVENTION
Description: The intervention consisted of 4 modules administered in the same number of face-to-face sessions in which educational strategies such as classes, guided discussions, workshops and a booklet designed for the study were used.
Study NCT06603454 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative CT
Description: Preoperative contrast enhanced CT
Study NCT06588595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prasugrel/Ticagrelor monotherapy or aspirin plus clopidogrel
Description: After at least 30 days of DAPT \[with aspirin 81-mg qd and a potent P2Y12 inhibitor (prasugrel 10 mg qd or ticagrelor 90-mg BID)\] in chronic coronary syndrome or after at least 90 days of DAPT in acute coronary syndromes; patients with an ABCD-GENE 10 or more will continue prasugrel 10 mg qd/ticagrelor 90 mg BID and drop aspirin; and patients with an ABCD-GENE less than10 will switch from prasugrel/ticagrelor-based DAPT to aspirin 81 mg qd plus clopidogrel 75 mg qd.
Study NCT06588595 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin plus clopidogrel
Description: After at least 30 days of DAPT \[with aspirin 81 mg qd and a potent P2Y12 inhibitor (prasugrel 10 mg qd or ticagrelor 90 mg BID)\] in chronic coronary syndrome or after at least 90 days of DAPT in acute coronary syndromes; patients will switch from prasugrel/ticagrelor-based DAPT to aspirin 81 mg qd plus clopidogrel 75 mg qd, irrespective of ABCD-GENE score.
Study NCT06588309 — intervention group
Intervention type: BEHAVIORAL
Intervention: Eye movement desensitization and reprocessing (EMDR)
Description: Integrated addiction and traumafocused treatment.
Study NCT06588309 — intervention group
Intervention type: BEHAVIORAL
Intervention: CRA
Description: CRA is a comprehensive cognitive behavioural treatment that focuses on helping people discover and adopt a pleasurable, social and healthy lifestyle that is more rewarding than a lifestyle including substance use.
Study NCT05104112 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The M.E.R. program
Description: The M.E.R program is a therapeutic education intervention for mothers of children with ASD during a new pregnancy. This program, which is a pilot in France and in Europe, involves several dimensions, both pedagogical and behavioral (strategies for stimulating the baby, use of specific communication and interaction tools) and psychological (reduction of stress, anxiety, etc. in the mother).~It includes 8 individual interviews of 1h30 every 15 days. The first and the last one are for evaluation purposes, the 6 intermediate sessions constitute the accompaniment. The structure of the program and the sessions are based on what is recommended in therapeutic education. The sessions can take place on the hospital site or at home.
Study NCT06604390 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: catechin extracts (health food)
Description: Type of intervention:~1. Purified gambir ≥ 90% (+)-Catechin~2. Dosage of 224 mg catechin capsule, once daily~3. Dosage of 224 mg placebo capsule, once daily~4. Cognitive function was assessed using MoCA-Ina and gene markers APP, MAPT, BDNF, IL-10, TGF-Beta and MDA Plasma.\&#34;
Study NCT06604390 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: catechin extracts (health food)
Description: Type of intervention:~1. Purified gambir ≥ 90% (+)-Catechin~2. Dosage of 224 mg catechin capsule, once daily~3. Dosage of 224 mg placebo capsule, once daily~4. Cognitive function was assessed using MoCA-Ina and gene markers APP, MAPT, BDNF, IL-10, TGF-Beta and MDA Plasma.\&#34;
Study NCT06398977 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin
Description: Dapagliflozin10MG, PO once daily
Study NCT06604390 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: plasebo
Description: Dosage of 224 mg placebo per capsule, once daily. Cognitive function was assessed using the MoCA-Ina and biomarkers including APP, MAPT, BDNF, IL-10, TGF-Beta, and plasma MDA.
Study NCT06604390 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: plasebo
Description: Dosage of 224 mg placebo per capsule, once daily. Cognitive function was assessed using the MoCA-Ina and biomarkers including APP, MAPT, BDNF, IL-10, TGF-Beta, and plasma MDA.
Study NCT05455879 — intervention group
Intervention type: OTHER
Intervention: Impact of antenatal corticosteroid therapy on surfactants use postnatal
Description: Intervention Description: Retrospective study on preterm infants to evaluate the impact of antenatal corticosteroid therapy on surfactants use postnatal
Study NCT06475872 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Crecheck Tablet 2.5 mg
Description: 2 tablets orally once a day
Study NCT06475872 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Crestor Tablet 5 mg
Description: 1 tablet orally once a day