AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05870566 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Corneal Crosslinking
Description: Riboflavin isotonic, 0,1 % Vitamin B2, with Dextran 20,0%, for epi-off procedure or Riboflavin isotonic 0,1% (Vitamin B2), 1,1% HPMC without Dextran for epi-off) 0.1% riboflavin-5-phosphate and 20% dextran T-500) will be applied to the cornea after epithelial debridement every 2 min for 10 minutes before irradiation and every 2 minutes during the course of a 10 minute exposure to 365 nm UV-A with an irradiance rate of 9 mW/cm2. This dose, mode and scheme of the intervention follows the internationally recognized accelerated CXL protocol (Elbaz et al. 2014). The data existing shows equivalent outcome regarding efficacy and safety compared to the standard protocol. To avoid any damage to the limbal stem cells, the limbus will not be irradiated during the procedure, as a CXL device (with maximal diameter of 11 mm) will be used. Furthermore, the limbal area will additionally be protected by a custom-cut LSC protection shield. (Protocol V04_0 Page 45-46)
Study NCT04690946 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive Behavioral Therapy
Description: 14-18 sessions of CBT
Study NCT04690946 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Emotion-Focused Therapy
Description: 14-18 sessions of EFT
Study NCT06650657 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: touchpoint method
Description: Touchpoint is a quality approach that can be applied to increase the sense of personal connection with the instructor, ensure that students are making satisfactory progress, increase instructor-student and student-instructor interactions, and increase student satisfaction, unlike traditional learning models.
Study NCT06650891 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Quercetin
Description: oral quercetin prior to surgery
Study NCT06650891 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: capsule identical looking to quercetin
Study NCT01395940 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KLH-2109
Study NCT05795894 — intervention group
Intervention type: BEHAVIORAL
Intervention: STAI-Y
Description: Situational Anxiety and Trait Anxiety Inventory
Study NCT05795894 — intervention group
Intervention type: BEHAVIORAL
Intervention: BDI scale
Description: • Beck Depression Inventory scale
Study NCT05795894 — intervention group
Intervention type: BEHAVIORAL
Intervention: M.I.N.I.Kid
Description: Suicidal risk module of the Mini-International Neuropsychiatric Interview child/adolescent version
Study NCT05795894 — intervention group
Intervention type: BEHAVIORAL
Intervention: PCL-5
Description: Post-traumatic Check List Scale
Study NCT04887922 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MIR Spirobank G
Description: FDA-approved, Bluetooth digital spirometer
Study NCT04887922 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ZEPHYRx®
Description: ZEPHYRx® has developed a 1) digital Bluetooth-enabled IS that allows for the continuous and objective remote monitoring of patient compliance with pre- and postoperative IS via a smartphone app and online provider dashboard.
Study NCT04887922 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional spirometer
Description: Will be provided to participants
Study NCT04887922 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Conventional spirometer
Description: Will be provided to participants
Study NCT06004986 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Administering Dupilumab 300 mg at different dosing intervals.
Study NCT05265208 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine will given at 1250mg/m², 2 times a day with an interval of about 12 hours between two intakes, 2 weeks on, 1 week off, for 4 pre-surgery cycles.
Study NCT05265208 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Selective Internal Radiotherapy (SIRT)
Description: During the first week of cycle 2 of capecitabine, patients will receive SIRT using Yttrium-90 glass microspheres. Treatment with Yttrium-90 glass microspheres requires two steps, one or two weeks apart. Both stages are performed under local anesthesia after a short hospitalization : the treatment simulation and therapeutic angiography.
Study NCT05265208 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Surgery will be performed according to local practice.
Study NCT05265208 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Surgery
Description: Surgery will be performed according to local practice.
Study NCT06271798 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Life style modification advice
Description: The lifestyle modification advice involves several key elements: reducing daily standing periods, avoiding excessive flexion of the knee joint during sitting, weight reduction, addressing cardio-respiratory conditions, incorporating venotonic agents, and utilizing below-knee elastic compression devices. These measures collectively aim to mitigate the development and progression of varicose veins, potentially preventing complications such as deep venous thrombosis and improving overall circulatory health.
Study NCT06271798 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistive exercise
Description: Participants in group A will perform resistive exercise. The patients will be instructed to do seated toe raises exercise or standing toe raise exercise. The exercise will be performed for 30 minutes, three times per week for six weeks.
Study NCT06271798 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercises
Description: Participants in group B will perform aerobic exercise. Each session will begin with 10 min of low-intensity treadmill walking for a warm-up. The subsequent aerobic component will involve incline treadmill walking for 20 min at a perceived exertion of 6-7 (i.e., somewhat hard) on Borg's 3-10 scale followed by 10 min of low-intensity treadmill walking for cool down. The exercise will be performed for 30 minutes, three times per week for six weeks.
Study NCT05137431 — intervention group
Intervention type: OTHER
Intervention: HFNO and NIV
Description: Patients meeting the inclusion criteria will be treated alternately with 2 hours of HFNO and 1 hour of NIV (HFNO-NIV for the same patient in turn). In 24 hours, there will be 16 hours of HFNO, 8 hours of NIV.~Parameters to record~* Respiratory parameters (respiratory rate)~* SpO2~* Ventilator settings~* Patient's tolerance (VAS; between 0-100)~* Arterial blood gas (HFNO and NIV at 1 hour)~* Clinical parameters (D dimer, CRP, ROX index)~Intubation criteria~* Loss of consciousness~* Agitation~* Persistent hypotension~* Need for fluid resuscitation~* Need for vasopressor~* Respiration rate ≥40/min~* SpO2 \<92~* pH\<7.30
Study NCT06650176 — intervention group
Intervention type: BEHAVIORAL
Intervention: Lifestyle Management
Description: The Metrikamind intervention features a unique digital ecosystem designed to manage mental health specifically in workplace contexts, with a focus on aiding recovery and facilitating the return to work for employees on sick leave. This innovative tool employs bifactor models to enhance the accuracy of self-reported data, effectively countering potential faking behaviors. Through continuous, real-time data collection on a user-friendly platform, Metrikamind tracks and assesses various mental health conditions, including stress, anxiety, and depression. The intervention\&amp;#39;s advanced analytics enable personalized feedback and targeted interventions, improving the detection, management, and ultimately, the mitigation of mental health issues. By focusing on individuals currently unable to work due to mental health challenges, Metrikamind aims to support their recovery and accelerate their readiness to return to work, thus addressing both immediate and long-term recovery trajectories.
Study NCT04258826 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LY3154207
Description: LY3154207 administered orally.
Study NCT04258826 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered orally.
Study NCT05491382 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Uphill running
Description: Participants will run at 70% of their maximal oxygen consumption for 60 min at a 10 degree (17.6%) incline.
Study NCT05491382 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Flatland running
Description: Participants will run at 70% of their maximal oxygen consumption for 60 min at a 0 degree (0%) incline.
Study NCT05491382 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Downhill running
Description: Participants will run at 70% of their maximal oxygen consumption for 60 min at a -10 degree (-17.6%) decline.
Study NCT05673954 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: C-Read test
Description: C-Read is a reliable and valid clinical tool for quantitatively testing the reading ability of readers of simplified Chinese characters.
Study NCT06346743 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fenofibrate
Description: Single dose of Fenofibrate will be given at dose of 10mg/Kg along with phototherapy for 24 hours before next blood sampling
Study NCT06346743 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Phototherapy
Description: only phototherapy will be given for 24 hours before next blood sampling
Study NCT06346743 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Phototherapy
Description: only phototherapy will be given for 24 hours before next blood sampling
Study NCT04269161 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Automatic control of inspired oxygen
Description: A device will be used to automatically adjust the blend of oxygen and air with the ability to return to manual control as needed.
Study NCT05198739 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video Interaction Project (VIP) program
Description: Video Interaction Project (VIP) is a strengths-based, family-centered intervention designed to enhance parenting practices/relationships and child development by promoting positive parenting practices such as pretend play, shared reading, and daily routines. In VIP's core component, a VIP coach video-records the parent / child for 3-5 minutes playing/reading with a provided toy and/or book, then reviews the video with the parent to facilitate self-reflection on the interaction and identifies and reinforces strengths. In the US, VIP is delivered in the context of pediatric primary care visits, with a COVID-19 remote adaptation (see Section 6 for details). Research staff will delivery VIP through video calls with subjects in Brazil.
Study NCT05177497 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1701
Description: SHR-1701 administered by iv
Study NCT05059366 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Manual Ventilation Grip Device
Description: Manual Ventilation Grip Device is an add-on device placed on a standard valve mask to assist ventilation.
Study NCT05059366 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 2VE
Description: the standard 2VE technique for ventilation
Study NCT04713488 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Sputnik Light
Description: solution for intramuscular injection Composition for 1 dose (0.5 ml)
Study NCT06433323 — intervention group
Intervention type: OTHER
Intervention: Anti-aging cosmetic care product
Description: This is an intra-individual comparison study.~* frequency of application: Once a day (in the evening)~* modalities of application: Apply the cream on the tested area determined by the randomization~* duration of investigational product application: 56 days (a window of + 72 hours is allowed)
Study NCT06263894 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Experimental group
Description: Alexander technique will be applied to the experimental group.
Study NCT06263894 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental group
Description: Alexander technique will be applied to the experimental group.
Study NCT05817838 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Financial Incentives
Description: For six months, families will receive weekly, $15 financial incentives to purchase healthy foods and beverages at a partnering Southeast Asian grocery store
Study NCT05817838 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Financial Incentives and Multilevel Multicomponent
Description: For six months, families will receive weekly, $15 financial incentives to purchase healthy foods and beverages at a partnering Southeast Asian grocer store, in-person, group-based nutrition education with other Southeast Asian families, text messages and motivational interviewing
Study NCT05817838 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: School Engagement
Description: For six months, families will attend in-person, group-based school engagement education with other Southeast Asian families designed to improve youths' academic outcomes. Families will receive text messages and motivational interviews. At the end of the six months, families will receive the equivalent of the six months worth of weekly, $15 financial incentives.
Study NCT05745311 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: The KPCXM18 injection
Description: Intravenous infusion
Study NCT05745311 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Intravenous infusion
Study NCT05340738 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: LyssnCBT
Description: LyssnCBT is a technology that allows therapists and supervisors access to tools that assist with assessing CBT session fidelity, including speech-to-text transcription, annotation tools, and AI-generated metrics.
Study NCT06437262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.20% CHX gel on saliva
Description: In vivo application of a gel on the vestibular and palatal/lingual gingival mucosa of both arches at minute 0 for posterior saliva collection at different time-points.
Study NCT06437262 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.20% CHX and Cymenol gel on saliva
Description: In vivo application of a gel on the vestibular and palatal/lingual gingival mucosa of both arches at minute 0 for posterior saliva collection at different time-points.
Study NCT06437262 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.20% CHX gel on oral biofilm
Description: Ex vivo application of a gel on the glass disks of the removable intraoral appliance at minute 0 for subsequent one-by-one disk removal from the device at different time-points.
Study NCT06437262 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 0.20% CHX and Cymenol gel on oral biofilm
Description: Ex vivo application of a gel on the glass disks of the removable intraoral appliance at minute 0 for subsequent one-by-one disk removal from the device at different time-points.
Study NCT05319509 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: gameChange
Description: Staff will explain the rationale behind gameChange, and briefly explain the different scenarios: a doctor's office, a waiting room, a pub, a café, a grocery store, a public street and a bus. Each scenario contains five levels, each increasing with anxiety stimuli and certain tasks the participant must complete. The participant will put on the Oculus headset, and go through a preliminary orientation game. The headset will be casted to an external monitor. Once they start gameChange, it will take the participants to the virtual therapist's room. They will be asked to choose which scenario they would like to participate in first and will complete all five levels for one scenario. Research staff will be taking event sampling-style observations of the participant. After completion of the levels, the participant will return to the virtual therapist's room for debriefing, and then will be asked to exit the game.
Study NCT05666765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isotretinoin ,silymarin
Description: 20mg/day isotretinoin for 3 months. 140 mg/day silymarin for 3 months. 20mg/day isotretinoin and 140mg/day silymarin for 3 months.
Study NCT06333795 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Faecal Microbiota Transplantation (FMT)
Description: Treatment is given as capsules.
Study NCT06333795 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Treatment is given as capsules.
Study NCT05273320 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nabilone
Description: Nabilone capsules at a maximum dose of 1 mg twice a day
Study NCT06457061 — intervention group
Intervention type: OTHER
Intervention: Survey Study
Description: Barthel Index for Activities of Daily Living Scale, Beck Depression Inventory and Star Cancellation Test questionnaires were applied to hemiplegia patients.~Beck Depression Inventory and Zarit Caregiver Burden Interview surveys were administered to caregivers.
Study NCT05201508 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Polyglactin mesh
Description: Polyglactin mesh is used in keyhole manner to enforce hiatal closure
Study NCT05201508 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sutures only
Description: Traditional hiatal closure with non-absorbable sutures.
Study NCT06409910 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Non-institutional-standard radiotherapy
Study NCT05597033 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise
Description: walking and handgrip exercise
Study NCT05204212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Left Atrial Appendage closure
Description: Percutaneous closure of the LAA
Study NCT04933383 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AQ001S 0.125 mg/ml
Description: administered by nebulization once daily
Study NCT04933383 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: AQ001S 0.125 mg/ml
Description: administered by nebulization once daily
Study NCT04933383 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Budesonide 0.125 mg/ml inhalation suspension
Description: administered by nebulization once daily
Study NCT04933383 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Budesonide 0.125 mg/ml inhalation suspension
Description: administered by nebulization once daily
Study NCT05385653 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: experimentation of the virtual reality RevBED
Description: ReVBED is a VR-based exposure scenario for CBT for the induction of food craving in patients with bulimia nervosa and binge eating disorder.~The use of ReVBED requires no VR experience and only generic and commonly used virtual reality tools (a computer with VR software, a wireless virtual reality headset, two controllers and headphones), all with a CE mark, allowing its users to move in and interact with a specially designed virtual environment.~This exhibit scenario takes place in a VR environment built to represent a standard apartment consisting of four exhibit rooms (a bedroom, a teenager's bedroom, a living room and a kitchen) in which the ReVBED user moves sequentially through the scenario. In each room, specific cues of craving are displayed. These cues are not only visual, but also audio, emotional and socio-environmental. A central hall connects the other rooms and serves as a safe place for debriefing, where measures such as craving are assessed.
Study NCT05385653 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: experimentation of the virtual reality RevBED
Description: ReVBED is a VR-based exposure scenario for CBT for the induction of food craving in patients with bulimia nervosa and binge eating disorder.~The use of ReVBED requires no VR experience and only generic and commonly used virtual reality tools (a computer with VR software, a wireless virtual reality headset, two controllers and headphones), all with a CE mark, allowing its users to move in and interact with a specially designed virtual environment.~This exhibit scenario takes place in a VR environment built to represent a standard apartment consisting of four exhibit rooms (a bedroom, a teenager's bedroom, a living room and a kitchen) in which the ReVBED user moves sequentially through the scenario. In each room, specific cues of craving are displayed. These cues are not only visual, but also audio, emotional and socio-environmental. A central hall connects the other rooms and serves as a safe place for debriefing, where measures such as craving are assessed.
Study NCT06582238 — intervention group
Intervention type: OTHER
Intervention: Dentists in Clinical Practice
Description: Experience in managing Dentine Hypersensitivity
Study NCT05597033 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control
Description: seated rest
Study NCT05432284 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (ambient air)
Study NCT05432284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: THC
Description: Pure THC vapor
Study NCT05432284 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Beta-Myrcene
Description: Pure beta-myrcene vapor
Study NCT05478356 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: low-dose atropine eye drops
Description: low-dose atropine eye drops
Study NCT05478356 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: orthokeratology
Description: orthokeratology, ortho-K lenses