AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05941897 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ceralasertib
Description: Participants will receive ceralasertib oral tablets.
Study NCT05941897 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Participants will receive durvalumab as an intravenous infusion
Study NCT04246112 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Handwriting intervention
Description: children will practice handwriting 5 days p/week, 15-20 minutes p/day for 12 weeks using the movalyzer software program.
Study NCT04387617 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cannabidiol
Description: The product is a liquid formulation that will be prescribed at a dosage of 20 mg per day for a total of 3 days.
Study NCT04387617 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The product is a liquid formulation placebo that will be prescribed at an equivalent volume as active drug for 3 days
Study NCT04831606 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: debridement
Description: Cleaning of the wound area
Study NCT04831606 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: debridement
Description: Cleaning of the wound area
Study NCT04831606 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Offloading
Description: Offloading performed with a standard brace to the calf (Optima Diab, from Molliter).
Study NCT05548127 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARV-471
Description: Daily oral dosages of ARV-471 continuously, dose escalation/de-escalation in Phase 1b until the recommended phase 2 dose (RP2D) determined, cycles lasting 28 days
Study NCT05548127 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Daily oral dosages of Abemaciclib continuously, cycles lasting 28 days
Study NCT06119087 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mechanical insufflation
Description: Mechanical insufflation (MI) is a chest physiotherapy exercise that will be performed using a type of mechanical insufflator-exsufflator (MI-E) known as the BiWaze Cough device. The device connects to a tube that can interface with a patient using either a facemask or mouthpiece.~Mechanical insufflation is a chest physiotherapy exercise that passively inflates the chest with positive pressure that is delivered in coordination with the patient's own inspiratory timing until maximal inflation capacity (MIC), determined by the patient or maximal chest rise on visual inspection. At MIC, the patient passively exhales, which completes one cycle. Prior literature has used a dose of 5 sets of 5 cycles once or twice daily. The maneuver is usually performed with assistance of a caregiver to hold the mask or mouthpiece in place.
Study NCT04863898 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Drug-use stigma reduction intervention for HIV care and treatment clinic staff
Description: We will adapt the HP+ health facility HIV stigma-reduction intervention to focus on drug stigma in HIV CTCs. The intervention will address key stigma drivers, including fear, awareness of stigma, and stigmatizing attitudes and beliefs, through a participatory training approach that involves all levels of staff and is grounded in social cognitive theory principles. The approach seeks to reduce stigma through fostering empathy, interpersonal interactions (contact strategies) and building efficacy for stigma reduction through awareness, skills, and knowledge building. The intervention consists of five-2.5 hour participatory training sessions.
Study NCT04831606 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Offloading
Description: Offloading performed with a standard brace to the calf (Optima Diab, from Molliter).
Study NCT04831606 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Advanced dressing
Description: Protect the wound with Advanced dressing
Study NCT04771767 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: Patients will receive 6 sub-anesthetic IV ketamine infusions over 8 weeks, each one lasting 40 minutes.
Study NCT04771767 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online Trauma-Focused Cognitive Behavioural Therapy
Description: Participants will enrol in a 12-week online CBT program mirroring in-person trauma-focused CBT.
Study NCT05453708 — intervention group
Intervention type: OTHER
Intervention: Survey
Description: One 15-20-minute survey
Study NCT02894827 — intervention group
Intervention type: BIOLOGICAL
Intervention: Blood sample
Study NCT02894827 — intervention group
Intervention type: OTHER
Intervention: Flow cytometry
Study NCT02894827 — intervention group
Intervention type: OTHER
Intervention: western blot
Study NCT04832334 — intervention group
Intervention type: OTHER
Intervention: Kinesthetic and Visual Imagery Questionnaire, Box and Block Test, Hand Lateralization Test.
Description: Imagery ability was determined.
Study NCT04832334 — intervention group
Intervention type: OTHER
Intervention: Berg Balance Scale, Functional Reach Test
Description: Balance level was determined.
Study NCT04832334 — intervention group
Intervention type: OTHER
Intervention: Timed Up and Go Test, Functional Independence Scale
Description: Functionality was evaluated.
Study NCT04622930 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Smartphone-delivered CBT for SAD
Description: 12-week Smartphone-delivered CBT for SAD. In-person cognitive-behavioral therapy (CBT) is an empirically supported treatment for SAD. The app-delivered CBT in this project includes modules such as cognitive skills (e.g., cognitive restructuring, core belief work), behavioral skills (e.g., exposure with ritual prevention), and perceptual retraining/mindfulness skills.
Study NCT04622930 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Smartphone-delivered CBT for SAD
Description: 12-week Smartphone-delivered CBT for SAD. In-person cognitive-behavioral therapy (CBT) is an empirically supported treatment for SAD. The app-delivered CBT in this project includes modules such as cognitive skills (e.g., cognitive restructuring, core belief work), behavioral skills (e.g., exposure with ritual prevention), and perceptual retraining/mindfulness skills.
Study NCT05606328 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Emergency Department Delirium Screening and Detection Program (ED-DDP)
Description: Champions will participate in a 1-day workshop, consisting of patient testimonials, small group discussions, delirium and screening tool use (didactics), and role-playing. Following the workshop, champions will receive 3 tele-training sessions; 2 to provide direct observation/feedback while the champion performs a bedside delirium screen, and 1 to provide direct observation/feedback of the champion providing training to the nurse. Once delirium champions complete training, they will provide bedside delirium training for all ED nurses. No adaptations to the ED-DDP will occur between implementation sites and no data will be collected during implementation phases.
Study NCT06021106 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing exercise application with virtual reality glasses
Description: In adapting breathing exercises to virtual reality glasses; The exercise video was first shot by the researcher in front of a green screen. Then, a 3D background design was made by a software developer, a 360-degree printout was taken, and it was converted into a form that can be viewed with glasses. The exercise video is prepared as 20 minutes. Exercises were performed at patients' homes through home visits. A total of 24 sessions of exercises were performed three days a week.
Study NCT06021106 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: routine treatment and care
Description: routine treatment and care
Study NCT04831606 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Advanced dressing
Description: Protect the wound with Advanced dressing
Study NCT04831606 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blue Light Photobiomodulation
Description: 2 minutes irradiation of blue light performed with EmoLED device
Study NCT05736770 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Respiratory rehabilitation and out of bed mobilization
Description: The Respiratory rehabilitation and out of bed mobilization group will perform following exercises: pre operative out of bed mobilization, active cycle breathing techniques, forced expiratory technique and volume based incentive spirometery
Study NCT05736770 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: The conventional exercise program group will perform :Flow based Incentive spirometery, Chest percussion if needed
Study NCT06481930 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Detection of Cervical Lesions by Fluorescence Photoelectric Image
Description: The enrolled patients underwent fluorescence photoelectric cervical lesion image detection, followed by colposcopy and biopsy to obtain histopathological results. The results of fluorescence photoelectric image detection were compared with histopathological results, and at the same time compared with HPV and TCT results at the time of enrollment.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 50 mg qd
Description: JYP0322 is administered orally at a dose of 50 mg qd for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 100 mg qd
Description: JYP0322 is administered orally at a dose of 100 mg qd for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 200 mg qd
Description: JYP0322 is administered orally at a dose of 200 mg qd for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 100 mg bid
Description: JYP0322 is administered orally at a dose of 100 mg bid for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 150 mg bid
Description: JYP0322 is administered orally at a dose of 150 mg bid for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT06128148 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JYP0322 200 mg bid
Description: JYP0322 is administered orally at a dose of 200 mg bid for a specified duration until unacceptable toxicity, disease progression, or study completion.
Study NCT05697965 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin
Description: applying 1 gm of vancomycin powder intracapsularly during primary total knee and hip arthroplasty to prevent periprosthetic joint infection
Study NCT05697965 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Total knee or total hip arthroplasty
Description: Primary total knee or total hip arthroplasty without using local vancomycin
Study NCT04805645 — intervention group
Intervention type: OTHER
Intervention: No intervention (Retrospective Cohort Observational)
Description: No intervention as this study is a Retrospective Cohort Observational
Study NCT05335135 — intervention group
Intervention type: OTHER
Intervention: TriageGO-MDW Clinical Decision Support
Description: TriageGO-MDW is non-device clinical decision support that provides patient-level clinical risk estimates based on clinical data derived from the electronic health record
Study NCT05335135 — intervention group
Intervention type: OTHER
Intervention: Usual Care
Description: Clinical care without decision support provided by TriageGo-MDW
Study NCT04813211 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: mobile artificial cervical vertebrae replacement
Description: 1. Position: The patient is in a supine position with the neck hyperextended, ensuring his/her neck and shoulders in a stable and neutral position before surgery and the cervical spine in a physiological curvature position.~2. Anesthesia: General anesthesia via oral tracheal intubation.~3. Surgical approach: Anterior cervical spine approach through the space between the visceral sheath and the vascular sheath.~4. Surgical method: Two intervertebral discs with adjacent lesions and part of the vertebral body between them will be removed. A curette is used to carefully strike off the annulus fibrosus and cartilage on the surface of the adjacent upper and lower endplates. Intraoperatively, the midlines of the segment and the vertebra to be replaced should be mapped out. When decompression, the midline for decompression should not be deviated from the planned midlines.
Study NCT04813211 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: anterior cervical corpectomy and fusion
Description: 1. Position: The patient is in a supine position with the neck hyperextended.~2. Anesthesia: General anesthesia via oral tracheal intubation.~3. Surgical approach: Anterior cervical spine approach through the space between the visceral sheath and the vascular sheath.~4. Surgical method: Two intervertebral discs with adjacent lesions and part of the vertebrae between them will be removed. A curette will be used to carefully strike off the annulus fibrosus and cartilage on the surface of the adjacent upper and lower endplates. The removed vertebral bone will be trimmed into cancellous bone particles and filled in a cervical titanium cage with an appropriate size. The titanium cage will be implanted into the vertebral space, and fixed with adjacent vertebrae using anterior cervical titanium plates and screws.
Study NCT05926791 — intervention group
Intervention type: OTHER
Intervention: Cosmetic product
Description: The educated group receives the cosmetic product SPF50+ according to the randomization list established at V1 and returns the products at V2
Study NCT05233085 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD4041
Description: Participants will receive oral solution of AZD4041 as stated in arm description.
Study NCT05233085 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive oral solution of placebo as stated in arm description.
Study NCT05012930 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baby Foods - Meat
Description: Commercially available baby foods
Study NCT05012930 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baby Foods - Dairy
Description: Commercially available baby foods
Study NCT05012930 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Baby Foods - Plant
Description: Commercially available baby foods
Study NCT05012930 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Foods from the home
Description: Caregiver will provide participant with usual foods from the home
Study NCT06592443 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LvL UP
Description: The LvL UP app includes four lifestyle intervention components centred around three core pillars, Move More (physical activity), Eat Well (healthy nutrition), and Stress Less (mental well-being), as follows: (i) conversational agent-delivered health literacy coaching sessions, (ii) daily Life Hacks (healthy habit suggestions), (iii) therapeutic Tools including step-based activity tracker, food diary, and journal and (iv) gamified slow-paced breathing training (Breeze). These components are delivered using an innovative engagement approach that combines storytelling, MI, feedback on progress, just-in-time adaptive notifications and gamification.~As part of the LvL UP app onboarding, participants are asked to nominate a 'LvL UP Buddy' (e.g., a friend, family member, or spouse) to provide additional support. Buddies are expected to complete different tasks, such as sending messages of encouragement or engaging in intervention-related activities together with the participant.
Study NCT06592443 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LvL UP + MI
Description: After 4 weeks, participants categorized as non-responders from the LvL UP group will be re-randomized into second-stage conditions: (i) continuing with the initial intervention (LvL UP) or (ii) additional human-delivered motivational interviewing (MI) support sessions (LvL UP + MI). The MI-informed sessions for non-responders will consist of four sessions delivered via WhatsApp, lasting between 30 and 40 minutes. The content of support will include various MI-based strategies such as use of ask-offer-ask framework and strategic use of communication skills (open-ended questions, reflections, affirmations and summaries) as per four MI processes:~* Engaging (foster collaboration and trust the research staff-user relationship)~* Focusing (conversation to focus on lifestyle changes)~* Evoking (elicit and strengthen participants' motivation towards lifestyle changes), and~* Planning (when the participant is ready, commitment to a change plan aimed at adopting a healthy lifestyle).
Study NCT06592443 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Comparison
Description: Participants randomised to the comparison condition will receive a study pack including physical activity, diet and mental well-being content extracted from existing Health Promotion Board (HPB) resources. Established in 2001, the HPB (https://hpb.gov.sg/) is a government organisation under the Ministry of Health committed to promoting healthy living in Singapore. HPB's organises health promotion and disease prevention programmes covering various health domains. HPB-developed resources were selected as the comparator because they are the 'go-to', nation-wide health resources in Singapore which cover LvL UP's domains.
Study NCT06615024 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: G6pd enzyme sickling test
Description: Measuring the enzyme level of G6PD and presence of Hbs
Study NCT06615024 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: G6PD enzyme and sickling test
Description: Measuring enzyme level of G6PD and level of HbS
Study NCT06615024 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: G6PD enzyme and HPLC
Description: Measuring G6PD enzyme level in neonates and measuring level of HbS
Study NCT06672900 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carbamazepine
Description: Commercially available supply.
Study NCT06672900 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole (Sporanox)
Description: Commercially available supply.
Study NCT06672900 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALG-000184
Description: Study Investigational Product
Study NCT06621329 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Transnasal sphenopalatine ganglion block
Description: Transnasal sphenopalatine ganglion blocks will be performed using the Tx360 device. Medications used during the procedure include 0.75% bupivacaine with or without 1 mg of preservative free dexamethasone.
Study NCT05621655 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Mid dose Recombinant Trivalent Subunit Rotavirus Vaccine
Description: 0.5 mL of vaccine containing a total of 60 µg of protein (20 µg of each P type) adjuvanted with 0.5 mg aluminum hydroxide.
Study NCT05621655 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: High dose Recombinant Trivalent Subunit Rotavirus Vaccine
Description: 0.5 mL of vaccine containing a total of 90 µg of protein (30 µg of each P type) adjuvanted with 0.5 mg aluminum hydroxide.
Study NCT06410885 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Thermal Anisotropy Measurement Device
Description: The study device is a non-invasive sensor that is placed on the study subject's skin overlying an existing implanted CSF shunt. It uses an integrated thermal actuator and temperature sensors to assess shunt flow.
Study NCT05380414 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tumor samples (archival FFPE) and blood samples
Description: Molecular screening
Study NCT06638996 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: CBG Intervention
Description: 50 mg CBG Administered
Study NCT06638996 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Intervention
Description: Participants will be administered a placebo
Study NCT05951751 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TRI-MOM intervention
Description: The TRI-MOM strategy includes 4 main activities:~1. Training of healthcare professionals in charge of maternal health (nurses, midwives and doctors in charge of maternal health services)~2. Triple screening of HIV, Syphilis and HBV by rapid diagnostic tests~3. Assessment and treatment of women positive for any of the 3 targeted infections~4. Raising awareness on MTCT among pregnant women visiting antenatal services and empowering women infected with at least one of the three infections
Study NCT05083468 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SR750 tablet
Description: The volunteers will be orally administrated by single or multiple dose of SR750 tablet with 240 mL water.
Study NCT05621655 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 0.5 mL per dose, containing 0.5 mg aluminium hydroxide adjuvant.
Study NCT06614556 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: Participants in the training groups performed bilateral hand grip resistance training three times per week for four weeks using a specialized hand-grip kit provided to them. Participants were provided with pictures and instructions for each exercise upon completion of the initial testing (PRE) session. They were asked to perform 12 training sessions (approximately 30-45 mins) over the 4 weeks according to their schedule. Each participant was asked to keep a training log to assist with accountability. Those assigned to the control groups were asked to maintain their normal daily activities throughout the four weeks.
Study NCT06616636 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Given by IV