AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04749108 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Early tumor response evaluation by MRI volumetry
Description: Two weeks after the CT completion, the tumor volume will be measured by MRI with specific software which automatically borders the tumor so as to determine the early tumor response. A centralized reassessment of all MRI exams will be systematically performed by two radiologists of the coordinator center.
Study NCT04749108 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiochemotherapy Cap 50
Description: RCT Cap 50 will combine radiotherapy at a dose of 50 Gy by either conventional 3D or Intensity-Modulated RadioTherapy (IMRT) (2 Gy per fraction, 5 fractions per week during 5 weeks / 44 Gy in mini pelvis, and boost 6 Gy on reduced peritumoral volume) with concomitant oral capecitabine at 1600 mg/m2 per day delivered the days of radiotherapy treatment (2 daily intake).
Study NCT04749108 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radical proctectomy with total mesorectal excision
Description: The proctectomy can be performed by laparoscopic surgery or conventional laparotomy.
Study NCT04749108 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radical proctectomy with total mesorectal excision
Description: The proctectomy can be performed by laparoscopic surgery or conventional laparotomy.
Study NCT05962164 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Passive Heat Therapy
Description: The intervention will consist of 6 weeks of repeated (3x/week) 45-min lower-leg immersions.
Study NCT05962164 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham Immersion
Description: The sham intervention will consist of 6 weeks of repeated (3x/week) 45-min lower-leg immersions.
Study NCT05179408 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Waitlist
Description: 8-week waiting period prior to targeted telerehabilitation
Study NCT06782464 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Treatment
Description: Treatment
Study NCT06782464 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Treatment
Description: Treatment
Study NCT06017128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: sexual counseling based on the PLISSIT model
Description: In the initial follow-up, the experimental group will receive information about total hip replacement surgery and its impact on sexual life based on the PLISSIT model. An educational booklet containing information about total hip replacement surgery, the rehabilitation process, and post-operative sexual life will also be prepared and distributed. In the second follow-up (5-7 days after surgery), the experimental group will be provided with information about home care before discharge and returning to sexual life.
Study NCT06782009 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calorie restriction
Description: Participants will be provided with a food menu guide for fifteen days with a 30% energy restriction (kcal) according to their usual diet, with a macronutrient distribution of 20-30% protein, 50-60% carbohydrates and 20-30% fat.
Study NCT06782009 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intermittent fasting 16/8
Description: Participants will be provided with a food menu guide for fifteen days with an energy intake according to the energy expenditure determined by indirect calorimetry with normal distribution of macronutrients. Intermittent fasting will be used with a time-restricted model of 16:8. For 16 hours, they will not be able to eat or drink calories. In the other 8 hours, they need to adhere to the energy-restricted diet.
Study NCT06782009 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: Participants will be provided with a food menu guide for 15 days with an energy intake according to the energy expenditure determined by indirect calorimetry, with the following distribution of macronutrients: 20-25% protein, 5-10% carbohydrates, 70-80% fat.
Study NCT06781788 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Making room for climate emotions in the classroom
Description: The Making room for climate emotions in the classroom program is designed to address emotions as students learn (formally or informally) about climate change. Each session features a drawing, photography, Lego sculpture, rock painting or collage/drawing workshop to address themes, explore emotions/feelings/experiences and initiate discussions on topics related to climate change.
Study NCT05751668 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Given IV
Study NCT05751668 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Paclitaxel
Description: Given IV
Study NCT05751668 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Monosialotetrahexosylganglioside
Description: Given IV
Study NCT05751668 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary Studies
Study NCT05751668 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary Studies
Study NCT05751668 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-life assessment
Description: Ancillary Studies
Study NCT05751668 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Quality-of-life assessment
Description: Ancillary Studies
Study NCT05751668 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Administration
Description: Given IV
Study NCT05720884 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: Acupuncture of a disposable, sterilized, stainless steel needle of 0.20 mm \* 30 mm size (Dongbang medical, Boryeong, Rep of Korea) will be used.
Study NCT05720884 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: placebo acupuncture
Description: Acupuncture of a disposable, sterilized, stainless steel needle of 0.20 mm \* 30 mm size (Dongbang medical, Boryeong, Rep of Korea) will be used but in differene location.
Study NCT06474117 — intervention group
Intervention type: OTHER
Intervention: Gait analysis coupled with ultrasound
Description: Measure the lengths of the Achilles tendon and gastrocnemius medialis muscle
Study NCT06474117 — intervention group
Intervention type: OTHER
Intervention: Isokinetic dynamometer with simultaneous ultrasound
Description: Measure the force/length profile of the gastrocnemius medialis muscle
Study NCT05175443 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Participants will be trained, by a physical therapist, to perform a set of four daily exercises requiring 1 sets of 2 minutes for each exercise totaling 8 minutes of targeted exercise per day for 8 weeks of the intervention. These exercises will be progressed or modified every 2-4 weeks to assure the participant is receiving maximal benefit for their exercise intervention.
Study NCT05935280 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Room temperature
Description: Room temperature injection
Study NCT05935280 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Cold temperature
Description: Cold temperature injection
Study NCT05935280 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cold temperature
Description: Cold temperature injection
Study NCT05935280 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cold temperature
Description: Cold temperature injection
Study NCT05935280 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocain
Description: Unspecific sodium channel blocker
Study NCT05935280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-05105679
Description: Specific antagonist of the TRPM8 ion channel
Study NCT05935280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A967079
Description: Specific antagonist of the TRPA1 ion channel
Study NCT05935280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-05089771
Description: Specific antagonist of the Nav1.7 sodium channel
Study NCT05935280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-06305591
Description: Specific antagonist of the Nav1.8 sodium channel
Study NCT05174650 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Infusion i.v. of atezolizumab on day 1 of a 3-week cycle, first infusion rate over 60 minutes, subsequent infusion rates 30 minutes if tolerated for a maximum of 20 cycles in total
Study NCT05174650 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Derazantinib
Description: Oral intake of 300 mg derazantinib continuously on day 1 to day 21 of a 3-week cycle for a maximum of 20 cycles in total
Study NCT06369324 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain education
Description: It consisted of holding information sessions on each of the days that the subjects were scheduled for treatment. These sessions will be supported by supplementary material in the form of brochures, posters and videos which briefly explain interesting knowledge about spondyloarthropathies.
Study NCT06369324 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise supervised by external focus
Description: This therapeutic exercise involves proprioceptive training with external feedback to enhance exercise execution and promote optimal postural control, particularly for individuals with back pain. The method, based on research by Abdollahipour et al. and Chiviacowsky et al., focuses on automatic control, reducing the cognitive load during exercises and improving movement retention. The Motion Guidance Clinician Kit will be utilized, consisting of a panel and laser guide for precise cervical movement. Exercises progress in difficulty over 12 sessions, targeting cervical and lumbopelvic stabilization, flexion-extension, rotations, and lateral flexions. Sessions start with seated exercises and progress to standing, with increasing distance between laser targets to expand cervical range of motion. Thoracic and lumbar exercises involve 10 repetitions each. The entire program lasts around 20 minutes and follows Tidier recommendations for intervention.
Study NCT06369324 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapy by means of electrical stimulation (electro-massage)
Description: This technique combines manual therapy (massage) with interferential current. Following a supervised therapeutic exercise program, this intervention targets the spine for 15 minutes. Using a Sonopuls 692® device, a bipolar current mode with specific frequencies is applied. The physiotherapist moistens sponges with warm water and administers the current through them while performing manual soft tissue therapy on the neck, shoulders, scapulae, thoracic, lumbar, and sacral areas. The intensity is adjusted to provide a strong but comfortable tingling sensation, without muscle twitching. The therapy sequence includes superficial stroking, deep gliding movements, trapezius kneading, muscle stretching, and deep rubbing on the thoracic and lumbar areas. The electro-massage protocol lasts 14 minutes.
Study NCT05555030 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iCura COVID-19 Antigen Rapid Home Test
Description: Candidate Ag self-test kit anterior nasal specimen collection and testing will be done under the supervision of qualified site personnel in person. Comparator NP samples shall be collected at least 15 minutes prior to Ag samples with at least 15 minutes between nasal collections including collections that may occur prior to study enrollment. Comparator samples will be collected first by qualified personnel at a study site or physician's office using an FDA authorized nasopharyngeal swab collection kit and SARS-CoV-2 molecular assay.
Study NCT05555030 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: RT-PCR Test
Description: High sensitivity RT-PCR COVID-19 Test
Study NCT06488326 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mulberry leaf extract 6 mg capsule
Description: Take one capsule of the sample one time.
Study NCT06488326 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mulberry leaf extract 12 mg capsule
Description: Take one capsule of the sample one time.
Study NCT06488326 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mulberry leaf extract 18 mg capsule
Description: Take one capsule of the sample one time.
Study NCT06488326 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsule
Description: Take one capsule of the sample one time.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrigenomix, personalized dietary plan
Description: Personalized dietary plan.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Activity
Description: Participate in an exercise program to work up to 300 min/week of moderate-intensity activity.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Participate in an exercise program to work up to 300 min/week of moderate-intensity activity.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral counseling
Description: Review behavioral counseling videos and participate in worksheets to assist with behavioral change.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral counseling
Description: Review behavioral counseling videos and participate in worksheets to assist with behavioral change.
Study NCT05956574 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Dietary plan
Description: Receive a standard dietary plan
Study NCT06340737 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CD22CART Infusion
Description: Dosing and Administration Participants will be hospitalized to receive treatment with CD22CART, if not previously hospitalized, and will remain hospitalized for approximately 5 to 7 (±2) days. Patients may be discharged once all AEs have resolved to Grade 1 or better, or at the discretion of the treating physician. Participants may be discharged with non critical and clinically stable or slowly improving toxicities (e.g., renal insufficiency, cytopenias) even if > Grade 1, if deemed appropriate by the investigator.
Study NCT05941182 — intervention group
Intervention type: OTHER
Intervention: online questionnaires
Description: Before and after online questionnaires
Study NCT05212116 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SDI-118
Description: SDI-118 is presented as low dose, and high dose capsules.
Study NCT06289621 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: False Safety Behavioral Elimination Treatment (FSET)
Description: 5-session transdiagnostic treatment for anxiety disorders and post-traumatic stress disorder (PTSD)
Study NCT06289621 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Enhanced Standard Care
Description: Participants in the enhanced standard care control group will receive treatment as usual and a list referrals.
Study NCT04676555 — intervention group
Intervention type: DRUG
Intervention: Ocrelizumab
Description: There is no treatment allocation. Patients administered Ocrelizumab by prescription that have started before inclusion of the patient into the study will be enrolled.
Study NCT04676555 — intervention group
Intervention type: DRUG
Intervention: Ofatumumab
Description: There is no treatment allocation. Patients administered Ofatumumab by prescription that have started before inclusion of the patient into the study will be enrolled.
Study NCT05606653 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Measurement of critical airway closing pressure
Description: Measurement of critical airway closing pressure
Study NCT05606653 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Respiratory function tests
Description: CO2 response test
Study NCT05606653 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: pharyngometry
Description: measure of the pharyngometry
Study NCT05993975 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacain 0.5%
Description: Bupivacaine hydrochloride was given without any adjuvant
Study NCT05993975 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain 0.5%
Description: Bupivacaine hydrochloride was given without any adjuvant
Study NCT05993975 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine Hydrochloride
Description: Use of Dexmedetomidine Hydrochloride 5 micrograms (1 mL) as an adjuvant with bupivacaine hydrochloride
Study NCT05212116 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The Matching Placebo for SDI-118 is mannitol in capsules.
Study NCT05623592 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: 17,5/15/10 mg Methotrexate subcutaneously
Study NCT05623592 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Sodium chloride
Description: Sodium chloride subcutaneously
Study NCT04876716 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azole
Description: Dosing according to the SPC
Study NCT06325475 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: labor with neuraxial labor analgesia
Description: Pregnant women in Group A will receive neuraxial labor analgesia (dural puncture epidural or combined spino epidural analgesia).~If postpartum analgesic needs arise, patients in Group A will receive 0.0625% bupivacaine via epidural route.
Study NCT06325475 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: labour without noroaxial labor analgesia
Description: Pregnant women in Group B will not receive neuraxial labor analgesia (dural puncture epidural or combined spino epidural analgesia).~If postpartum analgesic needs arise, patients in Group B will receive iboprufen and acetaminophen.
Study NCT05802849 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetazolamide
Description: Acetazolamide is a diuretic with a mild diuretic effect. Inhibits the enzyme carbonic anhydrase in the proximal convoluted tubule of the nephron. Increases urinary excretion of sodium, potassium, bicarbonate ions, does not affect the excretion of chlorine ions; causes an increase in urine pH.
Study NCT05156814 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Femoston® 1, Femoston® 2
Description: Femoston® 1 (1 mg estradiol / 10 mg dydrogesterone), Femoston® 2 (2 mg estradiol / 10 mg dydrogesterone)
Study NCT05156814 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Duphaston
Description: Duphaston®, 10 mg
Study NCT05156814 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Klimadynon
Description: Cimicifuga racemosa rhizomatum extract
Study NCT05156814 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Divigel
Description: Divigel, 0.1%
Study NCT06458660 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: LPP+: Mindfulness Meditation Delivered
Description: During the 6-week intervention period, participants will receive reminder SMS text messages at a time selected by the participant at 48 and 24-hrs before each scheduled study visit. Within 24 hours after every session, participants will receive an SMS text reminder to complete a session satisfaction survey. If the satisfaction surveys are not completed within 48 hours after each session, participants will receive an additional SMS text message once per day for three consecutive days after each planned study visit. Twenty-four hours before each scheduled study visit after study visit number 1, participants will an SMS text requiring a one-character response (1= yes, 2=no), asking if participants practiced any mindfulness meditation techniques since the last session. Participants who have not interacted with the app during the previous week will receive an accountability call to assess barriers to participation.
Study NCT06458660 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: LP
Description: LinkPositively is a culturally tailored, trauma-informed smartphone app for Black women living with HIV/AIDS affected by interpersonal violence. Core components of LinkPositively include: a) Virtual Peer Navigation that includes phone and text check-ins and 4 weekly one-on-one video sessions to build skills to cope with barriers and navigate care; b) Social Networking platform to receive peer support; c) Educational and Self-care database with healthy living and self-care tips; d) GPS-enabled Resource Locator for HIV care and ancillary support service agencies; and e) ART self-monitoring and reminder system.
Study NCT06269549 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Non-training Real Dietary Supplement (G1)
Description: One Active Joint capsule thrice daily, and one sachet (10g) Collagen Powder Blend once daily
Study NCT06269549 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Training Placebo Dietary Supplement (G2)
Description: One Active Joint placebo capsule thrice daily, and one sachet (10g) Collagen Powder Blend placebo once daily + physical exercise (60 minutes per session twice a week)
Study NCT06269549 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Training Real Dietary Supplement (G3)
Description: One Active Joint capsule thrice daily, and one sachet (10g) Collagen Powder Blend once daily + physical exercise (60 minutes per session twice a week)
Study NCT06111573 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: Study group using Vitamin D for myofascial pain treatment. Diagnostic Criteria for Temporomandibular Disorders was used in the diagnosis of patients with myofascial pain. Study group usind Vitamin D for myofascial pain treatment. Medical treatment with Vitamin D (10,000 IU/day) + Occlusal Splint treatment was applied. Occlusal Splints were made of hard acrylic with a flat surface and were used only for 8 hours during sleep for 3 months. 500 mg Paracetamol tablet was prescribed to the patients as a rescue painkiller if they needed painkillers.