AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02497222 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Study NCT05155124 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab + trifluridin tipiracil
Description: Cetuximab will be administered at a fixed dose of 500 mg/m2 once every 2 weeks; trifluridin tipiracil will be administered in a dose de-escalation design: dose level 1: 35 mg/m2 twice daily on days 1-5 once every 2 weeks; Or dose level 0: 30 mg/m2, twice daily, Days 1-5, once every 2 weeks;
Study NCT06445699 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Photodynamic therapy
Description: A number of studies have reported that PDT can accelerate wound healing by inactivating local bacterial infection and colonization of bacterial biofilm, promoting wound re-epithelialization.
Study NCT05673824 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Huaier Granule
Description: Treatment period: oral administration, 10g each time, 3 times a day. Continuous medication until the end of the study, failure of treatment, intolerable toxicity, withdrawal from the study for any reason or death, whichever occurs first; or after researcher's judgement, patient would no longer benefit from the treatment.~If the treatment of hepatobiliary malignancies needs to be changed due to disease progression, whether to continue the medication or not should be determined by the researcher.
Study NCT05673824 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VEGFR-TKIs
Description: Treatment period: Therapeutic agents were selected according to clinical routine, including but not limited to Sorafenib, Lenvatinib, Donafenib, Regorafenib, Apatinib and Cabozantinib. Continuous medication until disease progression, intolerable toxicity, withdrawal from the study for any reason or death, whichever occurs first. Refer to drug instructions for specific usage.
Study NCT05742412 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Video streaming (smartphone camera)
Description: Adding video streaming as a technical adjunct to the otherwise audio-based-only communication during emergency medical dispatch
Study NCT05742412 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Telephone (telephone microphone)
Description: Usual care: Audio-based-only communication using telephone during emergency medical dispatch
Study NCT05316480 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nimotuzumab
Description: nimotuzumab 200mg/week
Study NCT04934449 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Occlusal splint
Description: Using occlusal splints during sleep for 2 months
Study NCT05789693 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity changes
Description: Previously an initial measure (qualitative and qualitative) will be made to know the little active adolescents. At the end of the physical activity program a retention measure will be carried out to know the scope and persistence of the variables analyzed. The intervention will be developed with a frequency of three weekly sessions, of 60 minutes, in the period of the intervention, with the exception of weeks in which there is a public holiday, where there will take measures to recover the class. A schedule for the sessions will be set according to the interests of the participants and will be the same for all.
Study NCT06436040 — intervention group
Intervention type: OTHER
Intervention: Pathological response assessment
Description: The pathological response classification in our study was based on the histopathologic examination of the surgically resected specimens reviewed by two experienced pathologists.
Study NCT04551833 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levobupivacaine
Description: Tramadol versus Dexamethasone as adjuvant to Levobupvacain
Study NCT02014207 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment
Study NCT06088056 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination use of SRT with T-DXd
Description: Radiation therapy SRT will be implemented according to investigator's clinical practice(based on brain metastases number and tumor volume). T-DXd(5.4mg/kg, once per 21 days, initiated within 2 weeks after SRT) will be provided to patients with confirmed HER2 positive breast cancer and brain metastasis until tumor progression, a severe adverse event deemed related to the study drug, or death. All dose adjustments should be based on the most severe toxicity level (CTCAE version 5.0) that occurred. Two doses are allowed to be reduced.~Dose Level 0: 5.4mg/kg Dose Level 1 :4.4mg/kg Dose Level 2: 3.2mg/kg
Study NCT05379816 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 5% DW perineural injection
Description: 5% DW perineural injection to intercostal nerve
Study NCT03180463 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#)
Description: Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#) will be injected through surgery tunnel, 2\*10\^7 cells,
Study NCT03180463 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: core decompression
Description: The surgery will drill into the femoral neck (hip bone) and through the necrotic area of the bone that died from the lack of blood flow, take out partial osseous tissue.
Study NCT03180463 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: core decompression
Description: The surgery will drill into the femoral neck (hip bone) and through the necrotic area of the bone that died from the lack of blood flow, take out partial osseous tissue.
Study NCT06554561 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: 3-5mg d1-d14 for 4-6 cycles, every 21 days as induction/consolidation chemotherapy, Then 3-5mg d1-d14 for 12 cycles, every 28 days as maintenance treatment.
Study NCT06554561 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: 375mg/m2 intravenous infusion d1, every 3 weeks for 1 cycle, 4-6 cycles will be prescribed.
Study NCT06554561 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: 3.5g/m2 intravenous infusion for 4 hours in d1, every 21 days for 1 cycle, 4-6 cycles will be prescribed.
Study NCT06164691 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Blue light
Description: Participants undergoing this intervention will be exposed to blue (442nm) light.
Study NCT06164691 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Amber light
Description: Participants undergoing this intervention will be exposed to amber (617nm) light.
Study NCT05056883 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: K-237 0.3-0.4mg/kg (once daily)
Description: Ivermectin 3mg tablet
Study NCT05056883 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo 0.3-0.4mg/kg (once daily)
Description: Placebo 3mg tablet
Study NCT04672486 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: POD Adventures
Description: Participants in the intervention arm will receive information about local services/national helplines and a brief problem-solving intervention that is delivered through a smartphone app with telephone guidance from a lay counsellor. The intervention is grounded in stress-coping theory, with a technical focus on practical problem solving. The emphasis on problem solving reflects the primacy of psychosocial stressors in adolescent help-seeking. Moreover, problem-solving is among the most commonly used practice elements in evidence-based psychological interventions for children and adolescents globally.~The content of the app comprises two sections: 'Adventures' which teaches problem-solving concepts and methods through contextually-appropriate games; and 'My POD' which scaffolds the student through the application of step-by-step problem-solving procedures to their own prioritized problems.
Study NCT05903950 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Air cleaners with HEPA filter
Description: PM 2.5 exposure reduction using in home portable air cleaners fitted with HEPA filters
Study NCT05903950 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Air cleaners without HEPA filter
Description: Simulation of PM 2.5 exposure reduction using in home portable air cleaners without HEPA filters.
Study NCT05459766 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Action observation and motor imagery
Description: Observation and imagination of functional tasks that will be performed during the postoperative rehabilitation program.
Study NCT05459766 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Participants will be educated about the postoperative rehabilitation program
Study NCT05999149 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab Plus Chemotherapy and Famitinib
Description: camrelizumab+chemotherapy (Albumin-paclitaxel plus carboplatin)+Famitinib
Study NCT05999149 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Camrelizumab Plus Chemotherapy
Description: Camrelizumab Plus Chemotherapy
Study NCT06164691 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ambient White Light
Description: This cohort will be exposed to usual, ambient white lighting of the environment during chemotherapy and radiation treatments
Study NCT06080763 — intervention group
Intervention type: PROCEDURE
Intervention: Physical Therapy Management
Description: Physical therapy management is a routine intervention provided by physical therapists at Mahidol University's Physical Therapy Center for individuals with knee osteoarthritis.
Study NCT06377280 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Navina Mini
Description: CE-marked Navina Mini, released on the market May 2023
Study NCT05156437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin
Description: Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin
Study NCT05156437 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
Description: Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
Study NCT05156437 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
Description: Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
Study NCT04807166 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: Anlotinib
Description: Anlotinib will be administered orally,once a day (12 mg) on days 1-14 of a 21-day cycle
Study NCT04807166 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Drug: Carboplatin/Paclitaxel
Description: Paclitaxel 175 mg/m2 was given intravenously for 3 hours, D1 Carboplatin AUC 5 was given intravenously for 1 hour, D1
Study NCT05388227 — intervention group
Intervention type: OTHER
Intervention: Pole Walking
Description: Group training sessions will be offered at the participating independent living/retirement communities. Training sessions will be held either indoors or outdoors, 2-3 times a week, for 20-60 min/session, over 12 weeks.
Study NCT04998916 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Real TBS to the mPFC
Description: This will be delivered with the Magventure Magpro system; 600 pulses of continuous theta burst stimulation with the active sham coil (double blinded using the integrated active sham system).
Study NCT04998916 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham TBS to the mPFC
Description: This will be delivered with the Magventure Magpro system; 600 pulses with the active sham coil (double blinded using the integrated active sham system). The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the scalp. The electrodes are placed on the left frontalis muscle under the coil for both the real and sham stimulation sessions.
Study NCT05077540 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: oxytocin
Description: 20 unit of oxytocin infusion in 500 ml lactated ringer's solution 125 ml/h (Syntocinon, Novartis, Switzerland)
Study NCT05077540 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: misoprostol
Description: 800 µg sublingual misoprostol (Cytotec Pfizer, New York, USA)
Study NCT06333002 — intervention group
Intervention type: OTHER
Intervention: machine learning analysis
Description: We will use robust machine learning approaches, such as Random Forest, Extreme Gradient Boosting, Support Vector Machine and Multilayer Perceptron.
Study NCT05300893 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No night splint
Description: Instead of the usual treatment with a night splint for three months after percutaneous needle fasciotomy patients do not receive treatment with a night splint.
Study NCT00051090 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Telbivudine
Description: Administered orally at a daily dosage of 600 mg for a period of 48 weeks
Study NCT00051090 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lamivudine
Description: Administered orally at a total daily dosage of 300 mg for Weeks 24-48
Study NCT00051090 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Efavirenz
Description: Administered orally at a daily dose of 600 mg
Study NCT00051090 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Didanosine
Description: Administered orally at a total dosage of either 400 mg or 250 mg determined by individual weight
Study NCT06445699 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hydrogel dressing
Description: Hydrogel dressing is widely applied in clinical practice to improve the regeneration ability of wound granulation tissue, promote the division and migration of epithelial cells, speed up wound healing and relieve the pain.
Study NCT06445699 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hydrogel dressing
Description: Hydrogel dressing is widely applied in clinical practice to improve the regeneration ability of wound granulation tissue, promote the division and migration of epithelial cells, speed up wound healing and relieve the pain.
Study NCT05415423 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Developing an objective measure of experienced pain
Description: At the beginning of each study, participants are randomly allocated into one of two groups.~Within each group all participants are exposed to the same painful stimulus. One group experiences a painful stimulus of higher intensity compared to that of the other group. The painful stimuli are physically identical for every subject within the same group and within the standard of previous pain research.~Participants are then asked to evaluate the painful stimulus they just received according to a self-reported scale (NRS, VAS, gLMS, NRS-MB). Participants are also asked to decide multiple times whether they prefer a larger amount of money and experience the same or more painful stimulus they received before or a smaller amount of money and no (or a less) painful stimulus. The smaller amount of money is progressively increased across choices until it matches the larger amount, similar to multiple price-list methods (MPL) which are standard in economics.
Study NCT05415423 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Developing an objective measure of experienced pain
Description: At the beginning of each study, participants are randomly allocated into one of two groups.~Within each group all participants are exposed to the same painful stimulus. One group experiences a painful stimulus of higher intensity compared to that of the other group. The painful stimuli are physically identical for every subject within the same group and within the standard of previous pain research.~Participants are then asked to evaluate the painful stimulus they just received according to a self-reported scale (NRS, VAS, gLMS, NRS-MB). Participants are also asked to decide multiple times whether they prefer a larger amount of money and experience the same or more painful stimulus they received before or a smaller amount of money and no (or a less) painful stimulus. The smaller amount of money is progressively increased across choices until it matches the larger amount, similar to multiple price-list methods (MPL) which are standard in economics.
Study NCT05415423 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Developing an objective measure of experienced pain
Description: At the beginning of each study, participants are randomly allocated into one of two groups.~Within each group all participants are exposed to the same painful stimulus. One group experiences a painful stimulus of higher intensity compared to that of the other group. The painful stimuli are physically identical for every subject within the same group and within the standard of previous pain research.~Participants are then asked to evaluate the painful stimulus they just received according to a self-reported scale (NRS, VAS, gLMS, NRS-MB). Participants are also asked to decide multiple times whether they prefer a larger amount of money and experience the same or more painful stimulus they received before or a smaller amount of money and no (or a less) painful stimulus. The smaller amount of money is progressively increased across choices until it matches the larger amount, similar to multiple price-list methods (MPL) which are standard in economics.
Study NCT05741892 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fracture reposition with 3D printed patient specific repositions guides
Description: Comminuted tibial- or/and femur shaft fractures will be treated using 3D printed patient-specific repositions guides.
Study NCT02859831 — intervention group
Intervention type: OTHER
Intervention: water samples
Study NCT04037098 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Magnesium lactate.
Description: 2 tablets orally every 12 hours (equivalent to 360 mg of elemental magnesium) for 3 months
Study NCT04037098 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 2 tablets orally every 12 hours of on inert placebo for three months
Study NCT05321017 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MEP Operant Up-conditioning of the Wrist Extensor
Description: This is a training intervention in which the brain-spinal cord-muscle pathways are strengthened in individuals with incomplete spinal cord injury. Transcranial magnetic stimulation (TMS), a type of brain stimulation, will be used to elicit a muscle response from the wrist extensor (extensor carpi radialis), the muscle the bends the wrist back.
Study NCT05412316 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention: Short-wave diathermy
Description: The SWD will be applied using a CEC M-8 shortwave thermotherapy unit (CEC Electrónica S.R.L., Argentina) that emits RF at a frequency of 27.12 MHz. The device has two rectangular capacitive applicators (18 × 12 cm), which will be placed below and above the dominant shoulder. The coplanar application will be done using the continuous wave mode. The intensity of SWD will be gradually increased until the volunteer perceives a sensation of heat, and once familiar with this perception, the intensity will be increased until a sensation of constant but tolerable pain is evoked. This sensation will be maintained throughout the SWD application, and three repetitions will be performed. Healthy volunteers will be in a lateral supine position, and a cotton towel will be used to absorb perspiration and avoid unwanted heat effects.
Study NCT06004258 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Painless Vaccination
Description: Structural adaptation of the vaccination areas and cozy decoration (colorful room, mobiles to hang on the ceiling) Nursing uniforms decorated with children's pictures Introduction of toys, stuffed animals, stamps and reward stickers, drawings and crayons, soothing music in the background~Antalgic measures by age ranges:~0-6M (FLACC scale) Breastfeed for two minutes if infant is breastfeeding Glucose 33% or 50% or if rotavirus vaccination, on mother's pacifier or gloved finger (non-nutritive sucking) Comfort between vaccinations 6-15M (FLACC scale) Position infant sitting on guardian's lap facing forward Distraction techniques: stuffed animals, toys, audiovisual devices 3-6Y (Wong-Baker scale) Involve child, explain Child sits on tutor's lap facing forward Distraction techniques: audiovisual devices, drawings 6-14Y (VAS scale)Always seated. Distraction method: audio-visual devices, breathing
Study NCT05172323 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 3DCT-scan
Description: A contrast CT-scan of the coronary arteries will be performed and 3D analyzed to determine the best angle for the C-arm during Percutaneous Coronary Intervention (PCI) for stent implantation. Furthermore determining the amount and localization of calcium in the right coronary artery (RCA) and diameter and length of RCA. The use of IVUS will be used to determine the degree of calcium.
Study NCT05172323 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Angiography guided PCI
Description: Standard of care is angiography guided PCI of the ostium of the RCA. The use of IVUS will be used to determine the degree of calcium.
Study NCT05957016 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CIETAI-R
Description: 1. phase I: (1) Chemo-Immulo-embolization via Tumor Arterial, CIETAI: DSA guided tumor artery infusion of oxaliplatin 130 mg/m2+PD-1 inhibitor (Tirelizumab) 200mg, followed by gelatin sponge particles (350-560um) embolization~2. phase II: Chemoradiotherapy: IMRT：45Gy/25f/5w+capecitabine 1000，po. Bid d1-14, q3w Tirelizumab)200mg ivggt, d1, q3w
Study NCT04953273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vigitrauma
Description: Case management algorithm using early phone contact
Study NCT05803928 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lenvatinib + anti-PD-1 antibodies
Description: A ablation treatment group B ablation+ lenvatinib + anti-PD-1 antibodies treatment group