AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04989530 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporeal Shock Wave Therapy
Description: different energy levels of ESWT
Study NCT05415527 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Presence of sarcopenia evaluated prior to neoadjuvant chemotherapy and during chemotherapy as part of optimised management(dietician and APA).
Description: Sarcopenia will be evaluated by CT-scan. This method will be combined with a bone mineral density test which is also a way of entering into a more specific approach to sarcopenia screening.~The patients will receive optimised treatment by nutritional monitoring and adapted physical activity (APA) in addition to follow-up for sarcopenia.
Study NCT06667128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rapid Uptitration of Guideline-Directed Medical Therapy
Description: Rapid up-titration of GDMT guided by protocol-specific guideline.
Study NCT06667128 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Elecsys® NT-proBNP - Roche Diagnostics
Description: An assay provided by Roche (Elecsys® NT-proBNP - Roche Diagnostics) will be used to assess NT-proBNP levels in the Rapid Up-Titration GDMT Group with Point-of-Care (PoC) Monitoring, with the purpose of evaluating any differences in marker dosage between the indicated method and the monitoring by the hospital laboratory analysis.
Study NCT06667128 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rapid Up-Titration GDMT Group with Hospital Monitoring
Description: Rapid Up-Titration GDMT Group guided by protocol-specific guideline and hospital monitoring.
Study NCT06661759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinic-based and technology-supported sleep intervention
Description: CATS sleep intervention: The in-person sleep education and consultation will consist of 3 face-to-face, one-on-one sessions held 3 months apart during the child's routine clinic visit.The digital component of the sleep intervention will extend in-person education by providing ongoing support. Participants will receive one digital session per week for four weeks after the baseline, 3-month, and 6-month clinic visits, totaling 12 sessions.
Study NCT06667804 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laughter yoga
Description: Laughter yoga was applied to the experimental group for 4 weeks, 2 days a week, for 8 sessions (each session duration is 30-45 minutes on average). - The researcher is certified as an International Leader of Laughter Yoga. As a nursing intervention, patients with T2DM were made to do laughter yoga by the researcher. The laughter yoga program was conducted online (Google meet online) due to the ongoing COVID-19 pandemic at the time of the study. - The sessions were organized as follows: Monday-Thursday 10:00-10:45, Tuesday-Friday 10:00-10:45, Wednesday-Saturday 10:00-10:45. Participants participated in two sessions that were suitable for them within a week. A participant in a group was not allowed to change days in the following weeks.
Study NCT06668870 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supplemental Text Messaging
Description: Will receive education about the collection of patient-generated data, training in using the data collection tools, and guidance on the standard frequency for collection and sharing of information. Supplemental text messages will be sent to engage patients and deliver personalized reminders to complete monitoring tasks.
Study NCT06668870 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education and Training for Patient-Generated Data
Description: Will receive education about the collection of patient-generated data, training in using the data collection tools, and guidance on the standard frequency for collection and sharing of information.
Study NCT06672640 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote Exercise Program
Description: Participants in this group will engage in an eight-week exercise program conducted via video conferencing software. The sessions, which focus on balance, lower limb strength, and gait function, will be held twice weekly for 50 minutes each. Licensed physical therapists will supervise the sessions, and participants will exercise at home, with assistance from caregivers if necessary. The program aims to evaluate the effectiveness of remote exercise interventions in improving physical function and reducing the risk of falls in pre-frail older adults.
Study NCT06672640 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In-Person Exercise Program
Description: Participants in this group will take part in an eight-week in-person exercise program at a senior welfare center. The sessions will be held twice weekly for 50 minutes and will be led by a licensed physical therapist. The exercise program, which includes balance, lower limb strength, and gait training, is identical to that of the remote exercise group, with the primary difference being the mode of delivery (in-person at the welfare center). This group aims to assess the effectiveness of direct supervision in a controlled environment.
Study NCT06672640 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Physical Activity Education
Description: Participants in this group will receive educational materials about physical activity, including a booklet and one educational session. They will not participate in any structured exercise program but will be encouraged to maintain their usual activities. The control group serves as a baseline to compare the outcomes of exercise interventions against no structured exercise, focusing on evaluating usual care versus targeted exercise programs.
Study NCT05319535 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Implementation Strategy: Foundational REP
Description: Among Caregivers FIRST sites that do not meet implementation adoption benchmarks, the goal is to test implementation intensification approaches, specifically Foundational REP vs. Enhanced REP. The investigators propose that low intensity implementation support that promotes adapting Caregivers FIRST for context and provides tools for ongoing Caregivers FIRST evaluation (defined as foundational REP), will be sufficient for some but not all sites to successfully incorporate Caregivers FIRST into routine practice.
Study NCT05319535 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Implementation Strategy: Enhanced REP
Description: Among Caregivers FIRST sites that do not meet implementation adoption benchmarks, the goal is to test implementation intensification approaches, specifically Foundational REP vs. Enhanced REP. The investigators posit that higher intensity strategies (defined as Enhanced REP) that directly influence teams' capacity and skills to effectively self-organize and problem-solve will lead to higher implementation adoption, penetration, fidelity, and value.
Study NCT04333290 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [11C]MeDAS
Description: PET radiotracer
Study NCT06489678 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Robotic Assisted Bronchoscopy
Description: Cone-beam computed tomography (CBCT) technology and robotic-assisted bronchoscopy (RAB) present promising methods to enhance biopsy accuracy and procedural safety through 3-dimensional reconstructions and increased bronchoscope tip flexibility. Additionally, the transfer of navigational data between CBCT and RAB may further improve diagnostic yield. Given their distinct approaches to enhancing diagnostic outcomes, two separate study arms are warranted for CBCT and RAB.
Study NCT05188235 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acoustical Resonance Device
Description: Infants will be studied for 15 min using an electronic tuning fork to transmit sound through the hip from a point on the skin while transmitted sounds FDA-approved stethoscope
Study NCT05188235 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Acoustical Resonance Device
Description: Infants will be studied for 15 min using an electronic tuning fork to transmit sound through the hip from a point on the skin while transmitted sounds FDA-approved stethoscope
Study NCT05144542 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Participants smoke their usual brand of cigarettes for 26 weeks.
Description: Participants smoke their usual brand of cigarettes for 26 weeks.
Study NCT05144542 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Participants will vape electronic cigarettes for 26 weeks.
Description: Participants will vape electronic cigarettes for 26 weeks.
Study NCT05144542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Replacement
Description: Smoke usual brand of cigarettes
Study NCT05144542 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Replacement
Description: Vape e-cigarettes
Study NCT05144542 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Use smartphone to answer questions about nicotine cravings and mood, and log daily smoking activity every day.
Study NCT06049316 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scapular stabilization exercises
Description: In Scapular stabilization exercise, following treatment protocol will involve.~* In supine position, for the relaxation of body, patient will take a deep breath.~* In sitting position, patient will sit on the chair, placed both feet on the floor while bending knee at 90 degree. After this patient will raise his hand overhead with 90 degree flexion and elbow extension and also perform scapular retraction. (10 sec hold, 10 reps, 20 sec break).~* In quadrupled position with 120 degree flexion and shoulder abduction patient will lifted his hands. (10 sec hold, 10 reps, 20 sec break) TYI exercises will be administered~* T shape: Place both arms horizontal with thumbs up. (10 times, 5 sec hold, 3 sets)~* Y-shape: In prone lying place arms in 45 degree. (10 times, 5 sec hold, 3 sets)~* I-shape: In prone position patients will place his both arms overhead. (10 times, 5 sec hold, 3 sets).~These above exercises will perform 3 times a week for eight weeks.
Study NCT06462872 — intervention group
Intervention type: OTHER
Intervention: observational study
Description: It is an observational study
Study NCT03640377 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Praziquantel
Description: Praziquantel given as crushed tablets (40 or 80 mg/kg)
Study NCT05873621 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: ICG-guided lymphadenectomy
Description: Excision of ICG-fluorescent lymph nodes in addition to standard laparoscopic total mesorectal excision in rectal cancer patients after neoadjuvant chemoradiation
Study NCT05654207 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: WeCare
Description: WeCare combines two evidence-based strategies -- universal screening using the Computerized Adaptive Screen for Suicidal Youth and an adapted version of the SAFETY-ACUTE, which incorporates PI Lindsey's extensive work with Black youth, their families, and community stakeholders to develop culturally tailored strategies for addressing treatment barriers.
Study NCT04995926 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Labial mucosal epithelium grafting for corneal limbus substitution
Description: Labial mucosa epithelium grafting for corneal limbus substitution will be used to treat limbal stem cell deficiency by way of corneal surface re-epithelization
Study NCT01084486 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Study NCT05280808 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental phone app used for self-fitting of hearing aids
Description: This software allows participants to set up hearing aids as appropriate for their hearing loss
Study NCT04853537 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: intermittent fasting diet
Description: intermittent fasting diet to obese pregnant women >30 BMI and incidence of gestational diabetes
Study NCT05496738 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07264660 intravenous single ascending dose
Description: PF-07264660 will be administered intravenously in single ascending doses
Study NCT05496738 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-07264660 subcutaneous multiple ascending dose
Description: PF-07264660 will be administered subcutaneously in multiple ascending doses
Study NCT05496738 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Intravenous placebo
Description: Placebo will be administered intravenously in single ascending doses
Study NCT05496738 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: subcutaneous placebo
Description: Placebo will be administered subcutaneously in multiple ascending doses
Study NCT06049316 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Scapular functional exercises
Description: In Scapular functional exercises, following treatment protocol will involve~* Press-up (in a chair).~* Push-up plus, Grade 1, in oblique position exercise will be performed with the support of a table. After progression perform this in horizontal plane.~* Lateral pull down~* Horizontal pull apart~* Prone flexion: in prone position on plinth. Both arms placed overhead, and then raise arms towards ceiling.~* Prone rows: in prone position, with elbow straight, slowly raise arms towards ceiling while bending the elbows.~These all above exercises will perform by holding dumbbells in hands (20RM at first week, 10RM at last week) with 3 sets, 3 times a week for eight weeks.
Study NCT05028088 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sugammadex
Description: This study is a prospective, double-blind, low-intervention, non-randomized controlled clinical trial involving 99 patients with American Society of Anesthesiologists Ⅰ-Ⅲ, body mass index 18.5-24.9 kg/m2, who will undergo laparoscopic radical resection of liver cancer under general anesthesia in the Wuhan Union Hospital. Ultrasonography will be applied to monitor the change rate of diaphragm thickness at different time after extubation to evaluate the recovery rate of muscle relaxant, which indirectly reflects the dose-effect relationship of SUG antagonizing against rocuronium in patients with different liver Child-Pugh grades preoperatively.
Study NCT06209125 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: hybrid aesthetic functional appliance
Description: treatment of class II division one malocclusion
Study NCT04708054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Busulfan
Description: Given IV
Study NCT04708054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cladribine
Description: Given IV
Study NCT04708054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine Phosphate
Description: Given IV
Study NCT04708054 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hematopoietic Cell Transplantation
Description: Undergo stem cell transplantation
Study NCT04708054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thiotepa
Description: Given IV
Study NCT04708054 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT06519175 — intervention group
Intervention type: OTHER
Intervention: Conservative treatment
Description: Patients are provided with physiotherapy support and the provision of prostheses with the goal of ensuring as much walking functionality as possible.
Study NCT06519175 — intervention group
Intervention type: PROCEDURE
Intervention: Single or multi-stage surgery
Description: Correction of the deformity is pursued by one or more surgical procedures with the timing and the techniques (growth modulation, acute correction, gradual correction, soft tissues procedures, combined techniques) chosen according to the surgeon's preference to achieve the maximum possible walking functionality without orthopedic aids.
Study NCT06519175 — intervention group
Intervention type: PROCEDURE
Intervention: Amputation
Description: Limb surgery, whether or not associated with realignment or soft-tissue surgery, is performed, aimed at providing the maximum possible walking function through a prosthesis.
Study NCT05348694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Pendulum WBF-038
Description: All bacteria contained in Pendulum WBF-038 are commensal organisms that have been repeatedly documented to inhabit the human gastrointestinal tract under normal circumstances. Pendulum's WBF-038 is a proprietary formulation of the following strains: Akkermansia muciniphila, Clostridium butyricum, Clostridium beijerinckii, Anaerobutyricum hallii, Bifidobacterium infantis, plus chicory inulin and magnesium stearate. The organisms were grown under controlled conditions consistent with Good Manufacturing Practices (GMP) and employ no animal-derived products. All ingredients utilized during manufacturing were food grade and qualified as generally recognized as safe (GRAS).~The product is provided as acid-resistant capsules in bottles that are to be stored refrigerated at 4℃.
Study NCT05348694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Pendulum Placebo
Description: Pendulum placebo capsules containing magnesium stearate
Study NCT05034354 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Remote physiological monitoring
Description: Participants will be provided with a Bluetooth capable weight scale (A\&D Medical UC-352BLE or Beurer BY90), oxygen saturation monitor (Contec Medical Systems CMS50D-BT) and automatic blood pressure monitor (A\&D Medical UA- 651BLE) to use daily for at least 10 days of a 14-day trial period. Data will be sent via the Sphygmo App to the pediatric cardiology for monitoring. Parents and healthcare providers will be asked to participate in a qualitative interview and the end of the 14-day period to provide feedback on the devices and Sphygmo™ platform.
Study NCT04889651 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR9004
Description: BR9004: Abiraterone acetate 200mg, Boryung Pharmaceutical Co., Ltd.
Study NCT04889651 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR9004-1
Description: BR9004-1: Zytiga Tab. 500mg (Abiraterone acetate 500mg), Janssen Korea
Study NCT05948982 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Human Umbilical Cord Mesenchymal Stem Cells
Description: The stem cell infusion route is peripheral intravenous infusion, once every 4 weeks for a total of 3 infusions. All subjects received experimental drugs and conventional treatment during the study period.
Study NCT05648357 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fluarix Tetra Vaccine
Description: A single dose of Fluarix Tetra vaccine administered intramuscularly (IM) on day 1.
Study NCT04197505 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FLIR E95 camera
Description: Video will be recorded during the thermal reading for later computer analysis. The following variables will be analyzed: (1) the difference between the mean temperature between the injured and healthy extremities, (2) the difference between the maximum temperatures of both the injured and healthy extremities (ΔTmax), and (3) the difference between the area covered by each isotherm in both the injured and uninjured extremities (Δpix). FLIR software tools and MATLAB software will be used for the analysis.
Study NCT06066515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: survodutide
Description: once weekly subcutaneous injection
Study NCT06066515 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: once weekly subcutaneous injection
Study NCT05412420 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient Self-Reporting of Symptoms
Description: At baseline, clinical research staff will:~* verify the possibility of an internet connection at the patient's home~* help the patient to fill in the 1st questionnaire (baseline questionnaire - frailty)~Every two weeks for 3 months:~* patients complete questionnaires via app (toxicity; quality of life, medication adherence)~* responses are verified by clinical research staff~* In case of severe symptoms, the clinician contacts the patient and arranges for management.~At the end of the study :~- patients answer a satisfaction questionnaire
Study NCT06358677 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topical Tretinoin
Description: Topical tretinoin will be applied to one half of the face, either left or right side. The side the topical tretinoin will be applied to will be randomized.
Study NCT06358677 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: A placebo (topical moisturizer) will be applied to the other half of the face, either left or right side. The side the topical tretinoin will be applied to will be randomized.
Study NCT05524909 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genetic Risk Estimate
Description: The genetic risk information includes individual remaining-lifetime and 10-year genetic risk estimates for T2D as well as a dichotomized genetic risk category: 'increased genetic risk' (if their genetic risk is higher than the average population risk) or 'no increased genetic risk' (if their genetic risk is not higher than the average population risk).
Study NCT05524909 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Genetic Risk Estimate + Fitbit Functions
Description: The genetic risk information includes individual remaining-lifetime and 10-year genetic risk estimates for T2D as well as a dichotomized genetic risk category: 'increased genetic risk' (if their genetic risk is higher than the average population risk) or 'no increased genetic risk' (if their genetic risk is not higher than the average population risk).~The two unique Fitbit functions are step goal setting and prompts. Individualized daily step goals will be set to be 10% higher than participants' own baseline Fitbit step counts. The 'Reminder To Move' function of Fitbit will be used as a prompt to remind participants to reduce sedentary time and walk at least 250 steps/hour within a specified timeframe (i.e., from 9am to 10pm in the proposed research). If the user has not accumulated at least 250 steps/hour, a reminder (for example, 150 steps to go) will appear on the Fitbit screen at 10 minutes before the hour (for example, at 10:50 a.m.) and cause the device to vibrate.