AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05517447 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Observational cohort study
Description: Observational cohort study
Study NCT05517447 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Batoclimab
Description: Batoclimab is a fully human anti-neonatal fragment crystallizable receptor (FcRn) monoclonal antibody
Study NCT05429476 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tissue Plasminogen Activator (Alteplase)
Description: Tissue Plasminogen Activator (Alteplase) 0.9 mg/kg up to a maximum of 90mg, intravenous, 10% as bolus and the remainder over 1 hour~Other Names:~Actilyse Activase tPA r-tPA
Study NCT05459571 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Axicabtagene Ciloleucel
Description: Administered intravenously
Study NCT05459571 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Administered intravenously
Study NCT05459571 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Administered intravenously
Study NCT05459571 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Administered orally or intravenously
Study NCT05918835 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: High-frequency repetitive transcranial magnetic stimulation (active rTMS)
Description: HF-rTMS is applied with a figure-of-8 coil using the Magstim TMS System. Participants receive one administration of HF-rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). HF-rTMS is delivered at a frequency of 10 Hz for approximately 37 minutes (3000 total pulses).
Study NCT05918835 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham repetitive transcranial magnetic stimulation (sham rTMS)
Description: Sham rTMS is applied with a figure-of-8 sham coil using the Magstim TMS System, which is identical to the active coil, replicates the sounds of HF-rTMS, and is designed to mimic sensations of HF-rTMS. Participants receive one administration of sham rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). Sham rTMS is delivered for approximately 37 minutes (3000 total pulses).
Study NCT05859425 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Real-time rehabilitative ultrasound imaging (RUSI)
Description: Τhe ultrasound equipment used was B-K Μedical Mini Focus 1402 equipped with high frequency linear probe (8670, 5-12MHz) using standard musculoskeletal settings and the software: V 1.01.01.137. Ultrasound gel (AQUASONIC® 100, Parker Inc., Orange, NJ) was used as coupling agent. TrA imaging was initially performed with participants in crook lying, with the US head positioned along the lateral abdominal wall with reference points at the lower point of the rib cage (last rib) and the anterior superior iliac spine, on the right side of the person, midway between these two points. The US head was moved until tester (investigator) had the best possible visualization of the lateral abdominal muscles (external oblique, internal oblique and TrA). During the execution of the exercises, the participants could watch the ultrasound screen along with the therapist's guidance, thus receiving information (US-visual feedback) of their TrA activation
Study NCT05859425 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tactile feedback (control intervention)
Description: Palpatory-guided (manual) feedback for TrA activation
Study NCT06324825 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fuzhegn Nizeng Decoction
Description: Subjects taking prepared Fuzhegn Nizeng granules twice daily for 6 month.
Study NCT05023005 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Strain-Counterstrain treatment of piriformis muscle
Description: Participant will lay prone on table with affected leg close to edge of table. Piriformis muscle tender point is identified and palpated. Then patient leg is passively moved off table and passive hip flexion, abduction, and possible internal/external rotation is added to reduce tender point by 70% or more. This is done passively. This position is held for 90 seconds and then participant is passively returned back to neutral prone position with leg on table. Tender point is palpated again to reassess for change in pain (using subjective visual analog scale). An algometer is also used pre and post to assess objective change in pressure pain threshold.
Study NCT05023005 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Strain-Counterstrain treatment of piriformis muscle
Description: Participant will lay prone on table with affected leg close to edge of table. Piriformis muscle tender point is identified and palpated. Then patient leg is passively moved off table and passive hip flexion, abduction, and possible internal/external rotation is added to reduce tender point by 70% or more. This is done passively. This position is held for 90 seconds and then participant is passively returned back to neutral prone position with leg on table. Tender point is palpated again to reassess for change in pain (using subjective visual analog scale). An algometer is also used pre and post to assess objective change in pressure pain threshold.
Study NCT04757363 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: regorafenib
Description: regorafenib (80 mg on days 1-21 of the 28-day cycle)
Study NCT04757363 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: nivolumab
Description: nivolumab (240 mg on days 1 and 15 of the 28-day cycle).
Study NCT04757363 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FOLFOX chemotherapy with oxaliplatin
Description: FOLFOX chemotherapy with oxaliplatin (85 mg/m2 IV), leucovorin (400 mg/m2 IV), 5-FU (400 mg/m2 IV bolus), and 5-FU (2400 mg/m2/day continuous IV infusion over 48 h).
Study NCT06279923 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD19-BAFF Targeted CAR T-cells
Description: Each subject receive CD19-BAFF Targeted CAR T-cells by intravenous infusion
Study NCT04902248 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: The OTSC® System Set
Description: The endoscope was extracted and equipped with the OTSC system. OTSC system is deployed on the lesion with suction to target lesion
Study NCT04902248 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: angiographic embolization
Description: Transcatheter selective embolization to bleeding arteries
Study NCT04329806 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Moxonidine 0.2 MG
Description: Moxonidine 0.2 MG twice daily
Study NCT04329806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amlodipine 5 MG
Description: Amlodipine 5 MG twice daily
Study NCT06324825 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Moluodan granules
Description: Subjects taking prepared Moluodan granules 9g twice daily for 6 month.
Study NCT05413460 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcutaneous electrical acupoint stimulation
Description: Electrodes are placed at acupoints and connected to the stimulator. Electrical stimulation is given during surgery.
Study NCT04842682 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Combi 1 group
Description: CD40.HIVRI.Env and Poly-ICLC (Hiltonol), respectively at 1.0 and 1.0 mg/injection, i.e. 1 ml subcutaneous route in right deltoid; and combined with DNA at 4.0 mg/injection, i.e. 1 ml intramuscular route in left deltoid at weeks 0, 4 and 24~Or, NaCl at 0.9%, i.e 1 ml subcutaneous route in right deltoid and 1 ml intramuscular route in left deltoid at weeks 0, 4 and 24.
Study NCT04842682 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Combi 3 group
Description: CD40.HIVRI.Env and Poly-ICLC (Hiltonol), respectively at 3.0 and 1.0 mg/injection, i.e. 1.2 ml subcutaneous route in right deltoid; and combined with DNA at 4.0 mg/injection, i.e. 1 ml intramuscular route in left deltoid at weeks 0, 4 and 24~Or, NaCl at 0.9%, i.e 1.2 ml subcutaneous route in right deltoid and 1 ml intramuscular route in left deltoid at weeks 0, 4 and 24.
Study NCT06239311 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methotrexate
Description: Solution for injection in prefilled pen
Study NCT06239311 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Solution for injection in prefilled pen
Study NCT06106490 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: the effect of adding pulsed radiofrequency (PRF) modality to suprascapular nerve injection with ultrasound glenohumeral steroid in chronic shoulder pain patients
Description: Suprascapular nerve block group: Patients will receive ultrasound guided intra articular Gleno-humeral steroid injection of Diprofos® (betamethasone 14 mg/ 2ml) and ultrasound guided suprascapular nerve block US SSN with 10mL of 0.25% preservative-free bupivacaine~Pulsed radiofrequency group: Patients will receive ultrasound guided intra articular Gleno-humeral steroid injection of Diprofos® (betamethasone 14 mg/ 2ml) and ultrasound guided suprascapular nerve block US SSN with 10mL of 0.25% preservative-free bupivacaine with application of pulse PRF at 42 Celsius of suprascapular nerve for 480 seconds.
Study NCT06376331 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: washed microbiota transplantation
Description: The prepared microbiota suspension was infused into the participates' lower gut.
Study NCT06563336 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: EMG-driven hand robot training
Description: Robot rehabilitation program was applied with Hand of Hope®(Rehab-Robotics Company, Hong Kong), and EMG-driven exoskeleton. The biggest advantage of this system is that it measures the residual muscle activity values with surface EMG(sEMG) sensors. The residual muscles activity is used by giving feedback to the patient.~This treatment program, which was applied to both groups in the study, consisted of joint range of motion (ROM) exercises, stretching exercises for burn scars, strengthening exercises using putty or bands, and fine motor training such as writing and using a chopstick.
Study NCT06563336 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional occupational training
Description: This treatment program, which was applied to both groups in the study, consisted of joint range of motion (ROM) exercises, stretching exercises for burn scars, strengthening exercises using putty or bands, and fine motor training such as writing and using a chopstick.
Study NCT06563336 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional occupational training
Description: This treatment program, which was applied to both groups in the study, consisted of joint range of motion (ROM) exercises, stretching exercises for burn scars, strengthening exercises using putty or bands, and fine motor training such as writing and using a chopstick.
Study NCT06562452 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Injectable platelet rich fbirin
Description: fter the leveling and alignment phase, the canines were retracted with 150gm forces. The i-PRF was prepared from the blood of each patient then injected immediately before canine retraction on the buccal and palatal aspects of the extraction sites. Digital model were obtained at five time points: before tooth extraction (T0) and in the fourth week (T1), eighth week (T2), twelfth week (T3), sixteenth week (T4) from the beginning of distalization.
Study NCT06045546 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 5-5-5-8 technique
Description: the new technique of 5-5-5-8 for laparoscopic cholecystectomy
Study NCT06045546 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 10-10-10-5 technique
Description: the standard technique of 10-10-10-5 for laparoscopic cholecystectomy
Study NCT04821349 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Capsule endoscopy
Description: A consecutive series of patients recruited by 12 European centers based on the indication of OGIB will undergo capsule endoscopy examination.~Capsule endoscopy will be performed in each site according to local rules and requirements, and the study protocol will concern only the post-procedure analysis on reading modalities for each patient.
Study NCT05384769 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Liquid Biopsy
Description: Undergo liquid biopsy
Study NCT05384769 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low Dose Computed Tomography of the Chest
Description: Undergo low dose CT
Study NCT05384769 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT05959499 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR6002A
Description: One tablet administered alone
Study NCT05959499 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BR6002B
Description: One tablet administered alone
Study NCT05959499 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BR6002
Description: One capsule administered alone
Study NCT04718064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fingolimod
Description: fingolimod (Gilenya, Novartis) at a dosage of 0.5 mg once daily, for three consecutive days
Study NCT04718064 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo once daily, for three consecutive days,
Study NCT06069063 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zafirlukast
Description: Oral zafirlukast is approved to treat asthma and been shown in previous trials to be effective in blocking or mitigating the symptoms of people allergic to cat dander
Study NCT05434910 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Changes in mean arterial pressure
Description: MAP set at 65 mmHg for 25 min by infusion of noradrenaline. MAP set at 80 mmHg for 25 min by infusion of noradrenaline. MAP set at 95 mmHg for 25 min by infusion of noradrenaline.
Study NCT06205134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: A: Epinephrine injection
Description: Autoinjector for intramuscular, single-use, 0.3mg
Study NCT06205134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: B: FMXIN002 3.6mg
Description: Nasus Pharma nasal powder spray 3.6 mg, single use in one nostril
Study NCT06205134 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: C: FMXIN002 4.0mg
Description: Nasus Pharma nasal powder spray 4.0 mg, single use in one nostril
Study NCT05522361 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Risdiplam
Description: administered to participants per product label insert
Study NCT06081569 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: gait video; speech video; facial expression video;
Description: The videos of participants' gait, facial expression, and speech will be recorded and analyzed further. Other routine diagnostic tests will also be performed such as imaging of MRI, cognitive scales, etc.
Study NCT05355545 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtually supervised exercise
Description: Participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.
Study NCT05355545 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtually supervised exercise
Description: Participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.
Study NCT05355545 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health education
Description: Participants will first participate in a once weekly live health education class that they will access through a computer connected to the Internet. During the second half of the study, participants will participate twice weekly in an live exercise program that they will access through a computer connected to the Internet.
Study NCT06133933 — intervention group
Intervention type: DEVICE
Intervention: Pain Threshold using algometer/dolorimeter
Description: These patients who consent to participation in the study will receive a preoperative pain threshold measured using a pain algometer/dolorimeter. We will rely on the completion of the questionnaires, opioid consumption journal, and surveys to establish a correlation between pre-operative pain threshold and post-operative outcomes.
Study NCT05929352 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Musical Intervention
Description: A trained musician-facilitator will convene a series of four weekly two-hour sessions to which groups of five participants will be invited. The facilitator provides keyboard, professional microphone, recording interface, headphones, guitar, computer and a Digital Audio Workstation (DAW) for recording.
Study NCT04801589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: For patients in the dexmedetomidine group, dose will range from 0.2-2.0 mcg/kg/hr. For example, a 10 kg patient on an infusion of 1 mcg/kg/hr of dexmedetomidine would receive 10 mcg of study drug per hour. This dose range have been selected after literature review and discussions with critical care practitioners, investigational pharmacists, and the mini-MENDS study steering committee.
Study NCT04801589 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: For patients in the midazolam group, dose will range from 0.025-0.25 mg/kg/hr. For example, a 10 kg patient on an infusion of 0.15 mg/kg/hr of midazolam would receive 1.5 mg of midazolam per hour. This dose range have been selected after literature review and discussions with critical care practitioners, investigational pharmacists, and the mini-MENDS study steering committee.
Study NCT06560060 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: There are no interventions. The only medical procedure is a blood draw
Study NCT05548504 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Photon
Description: 50-66Gy/ 24 fractions, inhomogeneous dose distribution photon therapy
Study NCT05548504 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Proton
Description: 50-66Gy/ 24 fractions, inhomogeneous dose distribution proton therapy
Study NCT05087186 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Guided imagery and FLASH technique
Description: Five virtual group sessions delivered by psychological therapists;~* Sessions 1 and 2: Guided imagery~* Sessions 3 and 4: FLASH technique~* Session 5: Refresher on guided imagery and FLASH technique
Study NCT05401786 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ipilimumab
Description: Anti-CTLA-4
Study NCT06457932 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heart rate variability biofeedback training
Description: An 8-week intervention based on daily 10-minute HRV biofeedback training at rest using the Pulse HRV smartphone application.
Study NCT06457932 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Guided meditation
Description: An 8-week intervention based on daily 10-minute guided meditation sessions led by an instructor with over 20 years of experience in teaching meditation.
Study NCT05401786 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cemiplimab
Description: PD-1 inhibition
Study NCT05401786 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: Stereotactic Body Radiotherapy
Study NCT04772547 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vigabatrin Only Product
Description: enteral medication administration, serial blood draws, and outcome assessment
Study NCT05962372 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Culturally tailored food and diet advice
Description: Puerto Rico-tailored education includes strategies for healthy eating, preferences for traditional healthy foods, recommendations for limiting unhealthy traditional foods, portion sizes, etc.
Study NCT05962372 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard healthy eating advice
Description: Standard healthy eating education includes strategies, foods, portions, and cooking and eating tips included in the My Plate For A Healthy Puerto Rico dietary recommendations.
Study NCT05619419 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-enhanced positive affect induction
Description: Participants will receive brief psychoeducation about biopsychosocial pain management and practice with the MPAI via guided audio recording. They will then listen to the audio recording a final time before beginning the cold pressor test for experimental pain induction. They will be instructed to continue using the MPAI to manage pain during the cold pressor test.
Study NCT05619419 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Breathing Meditation
Description: Participants will receive brief psychoeducation about biopsychosocial pain management and practice with the BM via guided audio recording. They will then listen to the audio recording a final time before beginning the cold pressor test for experimental pain induction. They will be instructed to continue using the BM to manage pain during the cold pressor test.
Study NCT05838872 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Minuteful - Kidney Urine Analysis Test System
Description: Urine samples were collected and tested by a lay user, using the Minuteful - Kidney test device. The lay user test results were compared to the results obtained by testing the same urine sample on the comparison device, the URiSCAN Optima.