AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05210023 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: NUTRIGENETIC DIET INTERVENTION
Description: Weekly, personalized meal plans (menus) will be provided, prepared based on the anthropometric needs of the patients, with a caloric reduction (-500 kcal). These weekly menus (Sunday to Monday) consist of 5 meal times (breakfast, snack, lunch, snack and dinner). The distribution of the macronutrients: carbohydrates, proteins and fats, as well as the percentages of polyunsaturated, monounsaturated and saturated fatty acids, will be established according to certain nutrigenetic recommendations identified in the reference bibliography.~Participants included in this group will receive remote (virtual) nutritional counseling every 15 days.
Study NCT05210023 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CONVENTIONAL DIET INTERVENTION
Description: Weekly, personalized meal plans (menus) will be provided, prepared based on the anthropometric needs of the patients, with a caloric reduction (-500 kcal). These weekly menus (Sunday to Monday) consist of 5 meal times (breakfast, snack, lunch, snack and dinner). The distribution of the macronutrients: carbohydrates, proteins and fats, as well as the percentages of polyunsaturated, monounsaturated and saturated fatty acids, will be in accordance with the recommendations made by the WHO (World Health Organization), the AHA (American heart association) and the NOM (Official Mexican Standards) for the treatment of obesity and dyslipidemias.~Participants included in this group will receive remote (virtual) nutritional counseling every 15 days.
Study NCT06543641 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Coronary computed tomography angiography
Description: All patients received coronary computed tomography angiography.
Study NCT06543641 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Invasive coronary angiography
Description: According to the study criteria some of the patients received confirmation imaging with invasive coronary angiography.
Study NCT06434272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early exercise with partial Blood Flow Restriction
Description: The intervention comprises of 12 weeks of blood flow restriction exercise in weeks 1-12 after injury. Three weekly exercise sessions are performed. Six supervised sessions are provided during the 12 weeks.~Blood flow restriction of 80% of the limb occlusion pressure required to fully restrict the arterial blood flow is employed.~The intervention comprises three exercises: Seated leg extension, standing knee flexion, and seated heel-rise performed at home as an adjunct to usual care treatment.~Each exercise is performed in four sets of 30, 15, 15, +1 repetitions, with the fourth set (+1) being as many repetitions as possible.~Pause in between sets is 30 seconds. Pause in between exercises are 120 seconds.~In weeks 13-24, patients in this arm follow usual care treatment.
Study NCT06434272 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Late exercise with partial Blood Flow Restriction
Description: The intervention comprises of 12 weeks of blood flow restriction exercise in weeks 13-24 after injury. Three weekly exercise sessions are performed. Six supervised sessions are provided during the 12 weeks.~Blood flow restriction of 80% of the limb occlusion pressure required to fully restrict the arterial blood flow is employed.~The intervention comprises three exercises: Leg press in machine, heel-rise in machine, knee flexion in machine performed at training facilities as an adjunct to usual care treatment. If facilities are unavailable, three home-based exercises will be provided.~Each exercise, regardless of study arm, is performed in four sets of 30, 15, 15, +1 repetitions, with the fourth set (+1) being as many repetitions as possible.~In weeks 1-12, patients in this arm follow usual care treatment.
Study NCT05968014 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PENG vs FICB
Description: pericapsular nerve group block versus fascia iliaca compartment block
Study NCT04987632 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: Letrozole, an aromatase inhibitor, is considered to be the first-line drug for ovulation induction in PCOS.
Study NCT04987632 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Letrozole
Description: Letrozole, an aromatase inhibitor, is considered to be the first-line drug for ovulation induction in PCOS.
Study NCT04987632 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: acupuncture
Description: Domestic and foreign studies suggest that acupuncture and electroacupuncture can improve the menstrual cycle of PCOS and reduce the level of total testosterone; Acupuncture can regulate glucose homeostasis by stimulating the autonomic nervous system of PCOS patients. Our previous studies and a large number of literatures have proved that acupuncture can improve insulin resistance in PCOS, and acupuncture can improve the pregnancy rate in PCOS.
Study NCT04987632 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Governor vessel moxibustion
Description: It can warm the kidney, promote digestion and absorption, remove dampness and promote blood circulation
Study NCT05878392 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: bone filling materials
Description: the buccal jumping gap was packed using PRF in group 1 the buccal jumping gap was packed using xenograft in group 2 the buccal jumping gap was packed using Alloplastic β-tricalcium phosphate in group 3
Study NCT06360432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Participants will receive an 8-week program consisting of exercise training. It entails weekly group sessions, with each lasting an hour for 8 weeks. These sessions, designed for groups of approximately 10, will blend resistance and aerobic workouts to enhance muscle mass and strength while reducing fat in individuals with SO. Each session includes a 10-minute warm-up and cool-down, 20 minutes of resistance training using elastic bands, followed by a 20-minute brisk walking segment. Participants will also receive a YouTube link and a pamphlet describing the exercises, encouraging them to maintain at least 30 minutes of exercise five times a week during and beyond the supervised programme.
Study NCT06360432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The EatWellLog App
Description: Only participants in the M-health group will be instructed to use the EatWellLog app for daily diet self-management. This App supports participants with SO by providing a structured approach to managing a diet that encourages steady weight loss while maintaining muscle mass, in line with current nutritional recommendations for this demographic. The EatWellLog App has the following features: i) tracking participants' dietary habits by logging meals and snacks from a food list, ii) personalized online coaching and reminders by a multidisciplinary healthcare team, iii) participation of family caregivers through an interactive messaging function, iv) accessing health information via multiple channels, including animations, an at-a-glance display, and a reminder, and v) utilization of game elements, such as educational animations and video games to disseminate health and nutritional information related to SO.
Study NCT06061523 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sotorasib
Description: Oral Tablet
Study NCT04865601 — intervention group
Intervention type: OTHER
Intervention: resectomy of the colon
Description: The patient scheduled for colon resectomy are included in the study
Study NCT06545747 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: DCE-MRI based split-course hypo-RT
Description: Tumor delineation will be based on DCE-MRI and CT. MRI help define the tumor boundary. Different radiation doses will be delivered based on the Ktrans value of the tumor area on DCE-MRI.
Study NCT06545747 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: CT based split-course hypo-RT
Description: Tumor delineation will be based on CT. The total dose for both the first and boost courses of hypo-RT to the tumor area will be constant.
Study NCT06545747 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Concurrent chemotherapy
Description: Concurrent Chemotherapy consists of weekly albumin-bound paclitaxel 50mg/m2, d1 plus cisplatin 25mg/m2，d1.
Study NCT06545747 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Concurrent chemotherapy
Description: Concurrent Chemotherapy consists of weekly albumin-bound paclitaxel 50mg/m2, d1 plus cisplatin 25mg/m2，d1.
Study NCT06545747 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Consolidative immunotherapy
Description: Consolidative PD-1/PD-L1 inhibitors
Study NCT06545747 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Consolidative immunotherapy
Description: Consolidative PD-1/PD-L1 inhibitors
Study NCT06483581 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: M-TAPA block with bupivacaine 25%
Description: Following sterile conditions for bilateral M-TAPA block application, the transducer will be inserted on the chondrium in the sagittal plane at the 9-10th rib level. Subsequently, a deep angle will be created with the probe for visualization of the underside of the costochondrium. The sonovisible needle tip will be placed just below the chondrium and saline (5 ml) will be injected for site confirmation. After the confirmation, 20 ml of 0.25% bupivacaine will be administered for each group for a total of 40 ml of local anesthetic. Blocks will be applied using an 80 mm sonovisible needle with a 6-10 MHz linear probe under the guidance of a portable ultrasound. M-TAPA block with the same standard technique and drug dose will be applied to the contralateral side for each group of M-TAPA patients.
Study NCT06483581 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TAP block with bupivacaine 25%
Description: After the necessary sterilization conditions established, the linear ultrasound probe will be placed in the middle of the iliac crest with the end limit of the ribs. Starting with skin, the layers in descending order, subcutaneous adipose tissue, external oblique muscle, internal oblique muscle, transversus abdominis muscle, and peritoneum will be identified. As the tip of the 80 mm sonovisible needle passes through the muscular layers and fascia, the needle will be advanced in a controlled manner. After receiving the click sensation (passage of the fascia of the internal oblique muscle), the location of the needle will be fixed and 20 ml of 0.25% bupivacaine will be injected between internal oblique and transversus abdominis muscles. Same procedure will be performed to the other site. (40 ml local anesthetics in total)
Study NCT04948450 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity intervention
Description: Progressive resistance training (PRT) for the physical intervention will be provided at the nursing home for 45 minutes twice a week. The sessions will be organized in groups (10 patients/ group) and supervised by 2 physiotherapists. Within each small group (maximum 10), participants will follow the program tailored to their individual functioning level, with constant oversight by trainers.~People with dementia and care staff will be instructed to follow the prescribed PRT exercises for the rest of the week. Subjects will be encouraged to exercise daily.
Study NCT04948450 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive stimulation intervention
Description: The study subjects will receive cognitive intervention based on Cognitive Stimulation Therapy with rehabilitation experts. The intervention involves 14 sessions of themed activities, which typically run twice weekly. The sessions will be organized in groups (10 patients/ group).~People with dementia and their care staff will be instructed on how to practice the various activities at their nursing home for the rest of the week.
Study NCT04948450 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social intervention
Description: Social intervention will be combined with physical and cognitive interventions through doing these in a group, playing games during exercises (dancing, throwing ball to each other) or doing cognitive stimulation therapy in a group.
Study NCT04948450 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Management of metabolic and vascular risk factors
Description: Study physicians will assess the risk of developing new chronic diseases, change in blood pressure, weight and BMI, and hip and waist circumference, blood test (glucose, lipid parameters, fasting glucose, and HbA1C if the person with dementia has diabetes) at 3 and 6 months.~Participants in the intervention group will be provided with information on the importance of reducing risk factors, guidance on lifestyle changes and prescribing treatment if necessary by cardiologists and endocrinologists. The target for blood pressure is less than 120/90 mmHg and the target for HbA1c is less than 7.5 %.
Study NCT06038513 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transnasal Thermal Regulating Device
Description: Placement of transnasal thermal regulating device to reduce temperature in febrile patients for a period of 24 hours
Study NCT06203899 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Op Volle Kracht
Description: This is a preventive group training based on cognitive behavioural therapy for depression.
Study NCT06203899 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gatekeeperstraining
Description: This is a training for teachers to detect and address depressive symptoms and suicidality in their students .
Study NCT06203899 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Gatekeeperstraining
Description: This is a training for teachers to detect and address depressive symptoms and suicidality in their students .
Study NCT06014684 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Timing of exercise
Description: High Intensity Interval Training (HIIT) program for 12 weeks (3 per week/36 sessions in total)
Study NCT04860830 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 425809
Description: BI 425809
Study NCT05702177 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daridorexant 25 mg
Description: A single-dose of daridorexant 25 mg will be administered in the evening 30 minutes prior to bedtime.
Study NCT04860830 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05702177 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daridorexant 50 mg
Description: A single-dose of daridorexant 50 mg will be administered in the evening 30 minutes prior to bedtime.
Study NCT05702177 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A single-dose of placebo matching daridorexant will be administered in the evening 30 minutes prior to bedtime.
Study NCT06255015 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Breastfeeding toolkit card
Description: The card is delivered at 24 weeks and is also referred to in the 32 and 36 week antenatal meetings. It will also be referred to in the first 24 hours post-partum and in home visits.
Study NCT06350266 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Information about healthcare resources
Description: Text messages will be sent following discharge from the emergency department; text may also be modified in the (online and/or printed) discharge summary packet.
Study NCT05316311 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CERENOVUS ENTERPRISE 2 Intracranial Stent
Description: CERENOVUS ENTERPRISE 2 Intracranial Stent will be used to treat severe symptomatic intracranial artery stenosis.
Study NCT05576038 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: L-Tryptophan
Description: L-tryptophan is an essential amino acid responsible for activating the aryl hydrocarbon receptor (AhR). Dietary tryptophan is metabolized by the gut microbiota producing several 'indoles' such as (indole-3-aldehyde (IAld), indole-3-acetic acid (IAA), indole-3 propionic acid (IPA), indole-3-acetaldehyde (IAAld), indole-3-lactic acid (ILA) and indole-acrylic acid) and tryptamine, which are ligands for the AhR, a nuclear transcription factor involved in activating target genes responsible for maintaining gut integrity. Prior literature suggests that patients with active celiac disease have a lower functional capacity to produce these AhR ligands, which further impairs the AhR pathway. Hence, the aim of this study is to assess the effects of tryptophan supplementation in patients with celiac disease, non-responsive to a GFD for more than 1 year compared with the effects of an inactive, placebo comparator, L-leucine.
Study NCT05576038 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Freedom SimpleCap Powder
Description: Freedom SimpleCap Powder is a high functionality capsule and tablet excipient composite comprised of filler, glidant, disintegrant and lubricant (ingredients include: Microcrystalline Cellulose, Silicon Dioxide Colloidal, Sodium Starch Glycolate, Sodium Stearyl Fumarate). This capsule is dye, lactose and gluten free and will not interfere with the AhR pathway. Freedom SimpleCap Powder makes oral capsule formulation convenient, quick and simple Thus, this SimpleCap Powder will be an appropriate placebo comparator for this study.
Study NCT05582551 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Highlighting Patients at Risk for Sensory Screening (HPARSS)
Description: Collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the HPARSS document.
Study NCT05331755 — intervention group
Intervention type: DRUG
Intervention: Dupilumab
Description: start medication in cohort
Study NCT05590897 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Teeth Brushing
Description: All 52 participants were instructed through a lecture on how to perform toothbrushing with a fluoridated toothpaste (Colgate T®) and dental flossing three times per day after meals for 30 days. The Bass technique was taught, by which the bristles should be positioned at an approximate angle of 45º to the gingival pocket on both the free and proximal faces, with the performance of short, slightly circular vibrating movements.
Study NCT05590897 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dental Flossing
Description: All 52 participants were instructed to floss, 3 times a day after meals for 30 days.
Study NCT05590897 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tongue Scraping
Description: Tongue scraping was performed by the same operator for all participants. Posteroanterior movements were performed with the scraper on the dorsum of the tongue, followed by the cleaning of the scraper with gauze. The procedure was performed ten times on each participant to standardize mechanical removal.
Study NCT05590897 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Antimicrobial Photodynamic Therapy (aPDT)
Description: One session of aPDT was performed. The annatto photosensitizer was mixed at a concentration of 20% (Fórmula e Ação®, Brazil) in spray form, applied with a sufficient quantity to coat the middle third of the dorsum of the tongue (five sprays) and left for two minutes for incubation. The excess was removed with an aspirator. \|The surface of the tongue remained moist with the photosensitizer itself without the use of water. Six points were irradiated with a distance of 1 cm between points, considering the spread of the light and effectiveness of aPDT. The device was previously calibrated at a wavelength of 395-480 nm. Light was irradiated to ensure a beam area of 2 cm in diameter per point. Energy was 9.6 J and exposure time was 20 seconds per point.
Study NCT06194851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin nasal spray
Description: Veteran participants will self-administer 40 IU of intranasal oxytocin 30 minutes before the start of each bCBCT session.
Study NCT06194851 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline nasal spray
Description: Veteran participants will self-administer 40 IU of the placebo (intranasal saline spray) 30 minutes before the start of each bCBCT session.
Study NCT06194851 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Cognitive-Behavioral Conjoint Therapy
Description: Eight sessions of standardized bCBCT, a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning.
Study NCT06194851 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Brief Cognitive-Behavioral Conjoint Therapy
Description: Eight sessions of standardized bCBCT, a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning.
Study NCT05274841 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Support of relatives
Description: Screening of the support needs of relatives
Study NCT04936802 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcatheter tricuspid valve repair system (Trialign)
Description: To assess the Trialign System to treat subjects with moderate to severe tricuspid regurgitation
Study NCT04916964 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Test and exercise home-based program
Description: Eight home-based physiotherapy sessions will occur in two months, once a week, to activate the preserved implicit memory (PIM). The recommendations are to train three weeks with the same exercise program, three times a week (one time coached by the attributed physiotherapist and two times coached by a natural or family caregiver). After three weeks, the participants can choose if they want to keep the same exercises or change all or some of these, in testing other tasks. Every training session will be planned to last 45 minutes. During each training session, the participant will note on his/her own Training booklet each task performed. The Training booklet will be used to plane, organize, and remember details for the next training session.
Study NCT03770299 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Specified dose on specified days