AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06561594 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: recombinant human follicle-stimulating hormone-CTP Fusion protein injection
Description: IF Weight > 60kg，150ug, H. Administer the drug once every 14 days for 64 weeks；IF Weight >≤60kg，100ug, H. Administer the drug once every 14 days for 64 weeks
Study NCT06561594 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: recombinant human follicle-stimulating hormone-CTP Fusion protein injection Placebo
Description: 0.5ml, H. Administer the drug once every 14 days for 64 weeks
Study NCT05025085 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AGEN1777
Description: An immunoglobulin gamma (IgG1) antibody
Study NCT05025085 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: a PD-1 inhibitor
Description: Anti-programmed cell death protein 1 (Anti-PD-1) antibody monoclonal antibody
Study NCT05502679 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Weight bearing as tolerated
Description: Bearing weight on lower limb extremity
Study NCT05502679 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pragmatic Exercise protocol
Description: Designed exercise prescriptions according to the patients' needs
Study NCT05502679 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pragmatic Exercise protocol
Description: Designed exercise prescriptions according to the patients' needs
Study NCT04660864 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Nasal cavity cooling device.
Description: The RhinoChill® system cools by intranasal evaporation of a liquid coolant sprayed onto the surface of the nasal cavity. The RhinoChill® system is intended for use for the relief of pain and symptoms associated with acute migraine attack.
Study NCT05905276 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ERAS Protocol
Description: The ERAS protocol for ambulatory TURBT has been designed based on patient and provider input, a needs assessment of 150 patients in the hours after TURBT, a review of the literature, and experience with other ambulatory ERAS protocols already implemented at Johns Hopkins Hospital. The ERAS protocol for ambulatory TURBT aims to optimize care delivered in the pre, intra and postoperative settings.
Study NCT05905276 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: Patients in the usual care arm of the EMBRACE trial will experience the present-day care pathway of ambulatory TURBT at Johns Hopkins Hospital.
Study NCT06656286 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intra-Uterine suturing by X-TACK device and hysteroscope
Description: After general anesthesia and entering the abdomen with the laparoscope, Truclear hysteroscope with X-tack attached will be inserted to the uterine cavity. Insertion of normal saline to the cavity and applying 4 points suturing to the uterus. The procedure will be monitored by external laparoscopic camera located in the abdominal cavity. After the hysterectomy the uterus will be opened and the suture will be examine.~A preoperative intrauterine incision using a hysteroscope, followed by suturing, will be considered based on the success of the first procedure.
Study NCT06656949 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: injecting indocyanine green (ICG) dye Intraoperative
Description: injecting indocyanine green (ICG) dye Intraoperative for patients with endometrial cancer
Study NCT06656949 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: injecting indocyanine green (ICG) dye Intraoperative
Description: injecting indocyanine green (ICG) dye Intraoperative for patients with endometrial cancer
Study NCT06658808 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Promoting Community Conversations About Research to End Suicide
Description: Promoting Community Conversations About Research to End Suicide (PC CARES) trains local community health workers to facilitate a series of five 3-hour Learning Circles (LCs) over \~6 months to develop a 'community of practice' (CoP), whereby trusted adults of youth (a) learn about SPBPs; (b) tailor the SPBPs to their culture and community; (c) build cross-sector relationships (parents, teachers, etc.), and (d) do more to prevent suicide. Each session shares evidence-based, actionable ways to enhance social support, reduce harm/risk, and promote help seeking, which participants adapt and apply in their daily interactions with youth.
Study NCT06672250 — intervention group
Intervention type: OTHER
Intervention: CTCs/CTMs culture
Description: Collect the thrombosis from participants underwent catheter-based thrombectomy.To characterized by cancer-specific surface markers successfully and identify within the culture
Study NCT06737471 — intervention group
Intervention type: OTHER
Intervention: Intensive rehabilitation treatment
Description: A 3-hour daily rehabilitation treatment will be delivered to each patient 5 days a week for 5 weeks (45 hours) in the care units of the Hospital.~Rehabilitation will address the following macro goals: gross motor, manipulative, visual and visual-cognitive.
Study NCT06315881 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample and oral mucosa sample collection
Study NCT05464563 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroencephalogram
Description: An electroencephalogram is recorded during a task of rest then self-compassion and then empathy.
Study NCT05979597 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suprainguinal fascia iliaca block
Description: After the operation is completed, the fascia iliaca will be separated from the iliacus muscle. With ultrasound guidance, the local anesthetic injection will be made between the fascia and the muscle.
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cigarette
Description: Smoke usual brand cigarette
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Oral Pouch
Description: Insert low FBN R/S ONP
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Oral Pouch
Description: Insert low FBN > 99% S ONP
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Oral Pouch
Description: Insert high R/S ONP
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine Oral Pouch
Description: Insert high FBN > 99% ONP
Study NCT06315881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Smokeless Tobacco
Description: Insert ST
Study NCT06315881 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Survey Administration
Description: Ancillary studies
Study NCT06315881 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Text Message-Based Navigation Intervention
Description: Receive text with a link to daily diary surveys
Study NCT04707872 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MMDx diagnostic test
Description: Microarray test of gene expression in heart biopsies
Study NCT04707872 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Prospera
Description: Donor derived cell-free DNA in patient blood
Study NCT04707872 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: HLA antibody
Description: Centralized measurement of HLA antibodies in patient blood
Study NCT04617873 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bilateral STN-DBS and T10-T12 SCS
Description: simultaneous stimulation of bilaterally-STN-DBS combined with spinal cord stimulation
Study NCT04652596 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Produce prescription program
Description: A monthly $150 stipend will be provided to participants for 6 consecutive months to purchase fresh food items at mobile markets and independent farmers markets across Boston.
Study NCT04652596 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Grocery store gift cards
Description: A monthly value of $150 in grocery store gift cards redeemable at conventional grocery stores will be provided to participants for 6 consecutive months.
Study NCT06512402 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: patients will receive norepinephrine infusion at rate of 0.05 mcg/Kg/min
Study NCT06512402 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine
Description: patients will receive epinephrine infusion dose of 0.03 mcg/Kg/min
Study NCT06374810 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conscious Connected Breathwork
Description: Participants were taught the Conscious Connected Breathwork Technique. 2 facilitators were monitoring and coaching the participants to ensure adherence to the technique
Study NCT06374810 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo waitlist
Description: Participants were told the study was full and that they were placed on a waiting list until the 1st cohort had completed the breathwork program
Study NCT04939493 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rhythmic Auditory Cueing
Description: Patients will perform the same movement sequence in time with the metronome beat. The frequency of the rhythmic auditory stimulation will be matched to the participants preferred movement speed, which will be assessed prior to the start of the trial, and participants typically started moving after they had heard the metronome beat two to three times. Participants will be given sufficient practice trials to ensure full understanding before the actual recording of data, and will be given 3-minutes break between trials.~On the 3rd and 5th week, the rhythm frequency was increased by 5%.
Study NCT04939493 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bilateral arm training
Description: Training will consist of 20 minutes of bilateral arm training In each session, patients will be seated comfortably at a table in the following limb positions: ankles in neutral dorsiflexion, knees and hips placed at 90°, shoulders in 0° flexion, elbows in 60° flexion, and wrists in neutral position of flexion/extension
Study NCT04939493 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bilateral arm training
Description: Training will consist of 20 minutes of bilateral arm training In each session, patients will be seated comfortably at a table in the following limb positions: ankles in neutral dorsiflexion, knees and hips placed at 90°, shoulders in 0° flexion, elbows in 60° flexion, and wrists in neutral position of flexion/extension
Study NCT04939493 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy program
Description: Scapular mobilization. Thoracic spine mobilization. Mechanical assisted (active and passive) exercises. Therapeutic positioning as weight bearing on the paretic arm. Opening and closing closed fist. Strengthening exercise. Stretching of spastic muscles.
Study NCT04939493 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional physical therapy program
Description: Scapular mobilization. Thoracic spine mobilization. Mechanical assisted (active and passive) exercises. Therapeutic positioning as weight bearing on the paretic arm. Opening and closing closed fist. Strengthening exercise. Stretching of spastic muscles.
Study NCT05446675 — intervention group
Intervention type: PROCEDURE
Intervention: Endoscopic eTEP
Description: Endoscopic extended view totally extraperitoneal prosthesis repair.
Study NCT05446675 — intervention group
Intervention type: PROCEDURE
Intervention: Open Rives-Stoppa
Description: Open Rives-Stoppa repair with retromuscular mesh placement.
Study NCT05979597 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suprainguinal fascia iliaca block+dexamethasone
Description: After the operation is completed, the fascia iliaca will be separated from the iliacus muscle. With ultrasound guidance, the local anesthetic+dexamethasone injection will be made between the fascia and the muscle.
Study NCT06423027 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nature-Oriented Chatbots
Description: Nature-oriented chatbots are an intervention with nature-based video delivered by self-developed chatbots
Study NCT05528276 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Repair surgery
Description: 1. a circumscribing skin incision was made 2 mm below the hypospadias meatus,~2. penile degloving,~3. the para-urethral plate incision was made,~4. A vertical midline incision of the urethral plate was made from within the hypospadiac meatus and extended up to the mid-glans.~5. The urethral plate was tubularised, beginning proximally, and closed in two layers using 6/0 polyglactin 910 suture.~6. The neomeatus was formed on a catheter 2 F larger than the urethral stent.~7. A flap was harvested from the prepuce to cover the neourethra and finally glanuloplasty.~8. A suitable urethral stent was left in situ for 7-10 days, with a compressive dressing applied.~   * Grafted tubularised incised-plate .~1.Same steps but adding a graft (dorsal inlay) , 2. The graft will be taken from the inner preputial skin . 3. The graft will be sutured to overlying plate incision line from the old meatus to the tip of the glans.
Study NCT05442931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pregabalin 150mg
Description: The oral tablet half an hour preoperative 150 milligrams
Study NCT05442931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Magnesium Sulfate
Description: Intravenous administration half an hour preoperative 2 grams
Study NCT05442931 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nitroglycerin
Description: measure total dose of nitroglycerine in milligrams using a syringe pump
Study NCT05442931 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: surgeon satisfaction
Description: surgeon satisfaction measured according to Likert's scale
Study NCT03909503 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Porcine-derived collagen wound dressing
Description: Patients who meet the inclusion criteria will be treated with porcine-derived collagen dressings. The dressing will be used in accordance with its label. After cleansing the wound, the dressing will be placed on the wound. Appropriate primary and secondary dressings will be placed over the intervention product. Patients will visit the clinic once per week to have their dressings re-applied. Wound evaluations will take place once per week with the intervention lasting up to twelve weeks. Concomitant standard of care such as compression for venous ulcers will be provided according to individual patient needs.
Study NCT05647213 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: iPSC-CL
Description: Autologous IPSCL
Study NCT06265896 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesio taping
Description: Tape will be applied on rectus abdominis muscles using muscles facilitation technique from origin to insertion of muscle with a tension between 15-35%. Band will start on symphysis pubis with no tension and then women make stretch on the abdominal region by deep abdominal inspiration and will end at xiphoid process. Tape will be applied on the right and left external oblique muscles; the procedure will start without tension from bottom and of 6-12 ribs, then the hip will be placed in flexion and rotation to opposite direction and the tape will be attached to pubic bone with tension between 15-35%. Finally, the tape will be performed on the right and left internal oblique muscles; the procedure will start without tension from anterior superior iliac spine and then the hip will be placed in extension position and the tape will be attached to lower 4 ribs and linea alba with tension between 15-35%.
Study NCT06265896 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pelvic floor exercise training
Description: The intervention will be applied by a trained physical therapist. First of all, each participant will be instructed to relax thighs, bottom and abdomen musculature, then squeeze pelvic floor muscles 'focus on tightening without flexing abdomen, thighs or buttocks- avoid holding breath' 10 repetitions, 3 to 5 times a day (morning, afternoon, and night). Rest for 4 seconds and then repeat each contraction. Build up pelvic floor musculatures strength until each participant be able to do 10 slow contractions each time, holding them for 10 seconds each with rests of 4 seconds in between. Then do not hold your breath or tighten your stomach, bottom or thigh muscles at the same time. Will instruct participants to try holding each squeeze for a few seconds.
Study NCT06265896 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic floor exercise training
Description: The intervention will be applied by a trained physical therapist. First of all, each participant will be instructed to relax thighs, bottom and abdomen musculature, then squeeze pelvic floor muscles 'focus on tightening without flexing abdomen, thighs or buttocks- avoid holding breath' 10 repetitions, 3 to 5 times a day (morning, afternoon, and night). Rest for 4 seconds and then repeat each contraction. Build up pelvic floor musculatures strength until each participant be able to do 10 slow contractions each time, holding them for 10 seconds each with rests of 4 seconds in between. Then do not hold your breath or tighten your stomach, bottom or thigh muscles at the same time. Will instruct participants to try holding each squeeze for a few seconds.
Study NCT06346912 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD19-BAFF Targeted CAR T-cells
Description: Each subject receive CD19-BAFF Targeted CAR T-cells by intravenous infusion
Study NCT06334835 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: lncRNA signature analyses
Description: Evaluation of a signature of identified lncRNA in a cohort of childhood T-ALL patients in comparison with healthy subjects.
Study NCT05057624 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo GC-MRT
Description: Participants will hear music continuously throughout the trials, without regard to the faces they look at.
Study NCT05057624 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: GC-MRT
Description: Participants will hear music as a reward for looking at neutral faces and the music will stop when they focus on angry faces.
Study NCT05057624 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure
Description: Participants will hear music of their choice when they focus on angry faces, and when they look at neutral faces the music will stop.
Study NCT06177613 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blank culture transfer
Description: A maximum of 0.1 ml of gassed embryo culture medium preheated to 37°C is injected into the uterine cavity transcervically using an embryo transfer catheter placed just beyond the internal os, two to 3 days before transfer of the thawed embryo
Study NCT06177613 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham transfer
Description: An intermediate transfer step is added two or three days before the planned transfer of the frozen embryo but with an empty catheter.
Study NCT06016621 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Improvisational Music Therapy
Description: The therapist engages with the child by playing and sharing musical instruments, and/or sings while being attuned to the child's behaviour and expression. Various improvisational techniques are employed to engage the child. There are opportunities for pulse, rhythmic, dynamic or melodic patterns, and timbre to be mirrored, reinforced, or complemented, which allows for moments of synchronization between the therapist and the child, giving the child's musical expressions a pragmatic meaning within this context. The therapist may also gently provoke the child by violating expectations or patterns that have been jointly developed in order to elicit specific social communication behaviours. Further, there are opportunities for the child to develop and enhance social communication skills such as joint attention, sharing affect, reciprocity, shared history, scaffolding, imitation and turn-taking. These have been shown to develop social competency and also resilience.
Study NCT05065021 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: Niraparib works by blocking poly(ADP-ribose) polymerases (PARP) 1 and PARP 2 from working. PARP 1 and PARP 2 are proteins that are involved in cell growth, cell survival, and cell death, including cancer cells. It is believed that blocking PARP1 and PARP 2 from working will slow or stop the growth of cancer cells.
Study NCT05065021 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dostarlimab
Description: Dostarlimab is a monoclonal antibody. Antibodies are proteins that are naturally found in the blood stream that fight infections. A monoclonal antibody is a special kind of antibody that is created in a laboratory that seeks out specific proteins in the body that may be involved in cancers to stop tumor growth. Dostarlimab attaches to PD-1 and inhibits the interaction of PD-L1 and PD-L2 with PD-1.
Study NCT05065021 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab is a chemotherapy drug commonly used for the treatment of various cancers.
Study NCT05065021 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Paclitaxel
Description: Paclitaxel is a chemotherapy drug commonly used for the treatment of various cancers.
Study NCT06231108 — intervention group
Intervention type: OTHER
Intervention: Kinesio Taping
Description: Three different taping applications will be applied, namely ankle correction, quadriceps facilitation, and gluteus maximus facilitation.~1. Taping: Functional correction technique will be used to facilitate dorsal flexion movement.~2. Taping: Quadriceps Femoris (QF) Facilitation Technique - In taping to activate the QF muscle and regulate muscle tone, the patient will be placed in a supine position with hips and knees in neutral.~3. Taping: Gluteus Maximus (GM) Facilitation Technique - For taping to facilitate the GM muscle, a double-band application will be performed.