AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01517321 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo, MK-0431/ONO-5435
Description: Double-blind period (12 wks); placebo QD. The double-blind period will be followed by a 40 wk open label extension period where MK-0431/ONO-5435 could be titrated from 50 mg to 100 mg QD.
Study NCT05893641 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A lower exercise volume group
Description: Participate will conduct 85% of the control group weekly training volume (i.e., 30h/week)
Study NCT05893641 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: A longer rest group
Description: Participate will maintain the 35 h/week of exercise training
Study NCT04307563 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Mindfulness session
Description: 1.5 hour weekly session with health educator
Study NCT04928300 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: low dose dexmedetomidine infusion 0.2 µ/kg/hour IV for 5 days.
Study NCT04928300 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: low dose ketamine infusion 2.5 µ/kg/min for 5 days.
Study NCT04928300 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: 0.9% saline
Description: the same dose and duration of normal saline will be given for 5 days.
Study NCT06279286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HS-10506
Description: HS-10506, tablets (10mg, 20mg, 40mg and 80mg) at night once daily from Day 1 to Day 5 in phase Ib study, and from Day 1 to Day 28 in phase II study.
Study NCT06270615 — intervention group
Intervention type: OTHER
Intervention: Ambispective validation of machine learning-based predictive model
Description: Retrospective and prospective validation of a machine learning model to predict major haemorrhage in trauma patients compared to clinician prediction
Study NCT06378970 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audio Book Application
Description: The Audio Book Application Preference Form asked about book preferences other than horror and thriller genres. The selected audiobook was played with headphones via tablet/smartphone. Separate headphones were used for each patient. Patient Follow-up Form and Facial Anxiety Scale evaluations; the initial measurement (M0) was evaluated before the intervention, the first measurement (M1) at the 15th minute of the intervention, the second measurement (M2) at the 30th minute of the intervention, and the third measurement (M3) 30 minutes after the end of the intervention. Care was taken to ensure that there was no deterioration in the comfort of individuals due to the intervention. In the selection of audio books, language fluency, spelling rules and accessibility were taken into consideration and audiobook platforms to which the researchers were members were used.
Study NCT06192316 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3x3 between-subjects experimental exposure
Description: Participants will be randomly assigned to conditions in a 3 (Nicotine Concentration: None on label, Low, High) x 3 (Nicotine Source Claim: None, Tobacco Free, Synthetic Nicotine) between-subjects design. We will stratify randomization by young adult susceptible non-users and adult tobacco users for balance across the conditions. Participants will view 16 oral nicotine pouch pack images in random order that correspond to the nicotine concentration and source claim condition they are randomized to. Within each condition, pack images will vary by 4 brands and 4 flavors per brand. While viewing the images, we will collect psychophysiological data including heart rate, galvanic skin response, and eye tracking.
Study NCT06343324 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-based education
Description: Patients using noninvasive ventilation at home will receive detailed information about accessing, logging in and using web-based training. Pretest data will be collected, then week 4 and week 8 data will be collected.
Study NCT04858711 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ketamine-lidocaine-dexmedetomidine
Description: In the KLD group, patients will be administered 0,25 mcg/kg Dexmedetomidine in 100 mL of normal saline within 10 minutes. Followingly, they will receive 1mL/10 kg of the solution containing ketamine, lidocaine and dexmedetomidine at predefined concentrations. As maintenance, they will be receiving 1mL/10kg/h of the aforementioned solution.
Study NCT04858711 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: fentanyl
Description: In the fentanyl group, patients will be administered 2 mcg/kg fentanyl in 100 mL of normal saline within 10 minutes. Followingly, they will receive 1mL/10 kg of normal saline solution 0.9%. As maintenance, they will be receiving 1mL/10kg/h of normal saline solution 0.9%.
Study NCT05483647 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Local infiltrative anaesthesia
Description: In prone position, before the skin incision, patients in G1 underwent local infiltrative anaesthesia et the level of incision. The skin, subcutaneous tissue and muscles up to the foramen intervertebral were anesthetized by the surgeon employing forty millilitre solution of Lidocaine 1% with Dexamethasone 0.02% and Epinephrine 0.00018%.
Study NCT05483647 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spine plane block
Description: The transverse vertebral process of the required level of spine was identified using the mobile C-arm X-ray System. When the tip of the 22G needle reached to the transverse vertebral process 3 cm lateral to the spinous process, a solution of 40 millilitres of Lidocaine 1% with Dexamethasone 0.02% and Epinephrine 0.00018% was injected under the erector spinae muscle bilaterally.
Study NCT02716090 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adapalene and Benzoyl peroxide Dalap Duo®
Study NCT02716090 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Adapalene and Benzoyl peroxide Epiduo®
Study NCT05391438 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Meal-timing
Description: We propose a cross-over, proof-of-concept study to measure glycemic and metabolic responses to a test meal (controlled for macronutrient profile and caloric amount) administered at various times of the day (early vs. afternoon vs. late) in thirty Latino adolescents (ages 13-19 years), with obesity, without diabetes, to determine how timing of eating impacts glycemic response to the test meal after a 16-h fasting period. All participants will consume three standard test meals administered in random order at different times of day over two-weeks: (1) Early: test meal consumed at 8 AM; (2) Afternoon: test meal consumed at 12 PM; (3) Late: test meal consumed at 4 PM. A continuous glucose monitor (CGM) will be placed on the participant for the duration of the 2-week period. Baseline and post-meal samples will be assayed for glucose, insulin, c-peptide, GLP-1, GIP, PP at times -10, -5, 0, 10, 20, 30, 45, 60, 90, 120, 150 and 180 minutes after glucose.
Study NCT06545227 — intervention group
Intervention type: DEVICE
Intervention: continuous blood glucose monitoring in a subset of women (n=25) in the early monitoring group.
Description: To continuously monitor blood glucose from baseline to 28 weeks to determine if if there is hyperglycaemia in a subset of women (n=25)
Study NCT06279286 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo, placebo tablets matching the HS-10506 tablets
Study NCT06545227 — intervention group
Intervention type: OTHER
Intervention: Collection of urine, maternal blood at baseline and 28 weeks in a subset of women (n=25)
Description: To study maternal metabolome
Study NCT06545227 — intervention group
Intervention type: OTHER
Intervention: Collection of umbilical cord blood, placental samples and cord tissue in a subset of women (n=25)
Description: To study mesenchymal stem cell differentiation, change in fetal epigenetic and placental signalling pathways.
Study NCT06545227 — intervention group
Intervention type: OTHER
Intervention: Maternal and neonatal outcome data collection for all women in the study
Description: Data for maternal and neonatal outcomes will be collected
Study NCT04790383 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Advanced Self-Adhesive resin composite hybrid restorations (Surefil one (Dentsply Sirona)).
Description: Hybrid resin composite that doesn't need bonding system and releases calcium and flouride.
Study NCT04790383 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional resin composite restoration. (Sphere Tec, (Dentsply Sirona
Description: Conventional Nanohybrid resin composite
Study NCT05843227 — intervention group
Intervention type: OTHER
Intervention: questionnaire on the organizational management
Description: Data are collected through a questionnaire on the organizational management of the pre-operative / intraoperative / postoperative periods.
Study NCT05145972 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Guided Superior Hypogastric Plexus
Description: The division of abdominal aorta into common iliac arteries will be identified by using longitudinal sonography , and the body of the fifth (5th) Lumbar vertebra will be identified by placing the transducer transversely. A skin wheal will be raised with subcutaneous infiltration with 2% lidocaine solution nearly 3-4 cm below the umbilicus. A 15-cm Long 22-G Chiba needle will be used with out of plane technique, and the needle will be advanced under USG-guidance to reach the anterior- most point of the fifth Lumber vertebral body avoiding the vascular structures. The needle will be withdrawn nearly 1-2 mm after hitting the vertebral body to avoid injecting the drug into the periosteum. After confirming a negative aspiration of blood, known amount of neurolytic agent according to the grouping will be injected for the neurolysis of superior hypogastric plexus. The uniform spread of the drug will be confirmed under real-time sonography.
Study NCT05166096 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rho-11
Description: Subjects will be administered 325 mg aspirin by rapid IV push
Study NCT05166096 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: aspirin 325mg
Description: Subjects will be administered 325 mg aspirin orally
Study NCT05230732 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: neuromodulation device
Description: Active LLTS will be performed by use of a neuromodulation device with electrodes attached to the tragus of the ear. Stimulator will be applied continuously for 1 hour daily for 12 weeks
Study NCT05230732 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SHAM
Description: Sham LLTS will be performed by use of a neuromodulation device with electrodes attached to the ear lobule. Stimulator will be applied continuously for 1 hour daily for 12 weeks
Study NCT01014676 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic
Study NCT01014676 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT05055596 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tai Chi
Description: Qigong/Tai Chi Easy is a manualized intervention with formal training for instructors through the Institute of Integral Qigong and Tai Chi (IIQTC). The protocol can be modified based on participant needs and physical abilities. Qigong/Tai Chi Easy uses a series of repeated and simple-to-learn movements (rather than long forms with complicated choreography).
Study NCT05055596 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Health Coaching
Description: The Health Education group will be adapted from a previously developed time and attention control condition used in HIV research. Additional health education material will be based on information learned in the qualitative interviews conducted prior to the start of this study. Examples of session material include the following: sleep hygiene, healthy diet, sun safety, and healthy homes.
Study NCT05179629 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: M TAPA block
Description: Under aseptic conditions, a high frequency linear probe will be placed on the costochondral angle in the sagittal plane. Then the probe will be slightly angled deeply to visualize the lower view of the perichondrium. We will perform M-TAPA with totally 30 ml (15 ml for each side) of %0,25 bupivacaine.
Study NCT06272097 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention program based on TIME-CDST tool led by wound specialist nurses
Description: Based on the TIME CDST tool led by wound specialist nurses, which includes the following four areas: A. Assess patient, well-being and wound; B. Bring in multidisciplinary team and informal carers to promote holistic patient care; C. Control or treat underlying causes and barriers to wound healing; D. Decide appropriate treatment.
Study NCT06272097 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: A routine wound care program
Description: A routine wound care program of wound cleaning and dressing changes
Study NCT04708587 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: dual anti-platelet therapy at least 6 months
Description: Patients enrolled in dual antiplatelets at least 6 months arm would be administered with aspirin 100mg plus clopidogrel 75mg or prasugrel 10mg once daily for at least 6 months after randomization. Clopidogrel or prasugrel should be maintained after 6 months.
Study NCT04708587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dual anti-platelet therapy 3months or less
Description: Patient enrolled in the dual antiplatelet therapy less than 3 months arm would be administered with aspirin 100mg plus clopidogrel 75mg or prasugrel 10mg once daily for less than 3 months after randomization. After 3 months clopidogrel or prasugrel should be maintained.
Study NCT06238063 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led Advance Care Planning (ACP) Intervention
Description: An ACP discussion between the participating resident, family members, and the trained nurse will be incorporated into the annual review. The proposed ACP intervention will be divided into three parts (three weekly sessions, 1.5 hours each): 1) preparatory, 2) discussion, and 3) follow-up sessions.
Study NCT05733819 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Subject-specific optimized RAS
Description: Walking with metronome-based RAS cueing
Study NCT05733819 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active Walking
Description: Walking without RAS cueing
Study NCT05733819 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Walking
Description: Walking without RAS cueing
Study NCT06077669 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: Single oral dose of methylphenidate (5mg or 10 mg)
Study NCT06077669 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral placebo
Study NCT04783051 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sulfadoxine pyrimethamine
Description: Intermittent Preventive Treatment in pregnant women with Sulfadoxine-Pyrimethamine
Study NCT04783051 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pyramax
Description: Intermittent screening using ultra-sensitive malaria Rapid Diagnostic test and treatment using Pyronaridine - Artesunate (PYRAMAX®)
Study NCT06122298 — intervention group
Intervention type: OTHER
Intervention: fMRI
Description: A brain imaging technique that measures in vivo the activity of brain areas by detecting local changes in blood flow.
Study NCT06122298 — intervention group
Intervention type: OTHER
Intervention: Ecological Momentary Assessment
Description: studies people's thoughts and behaviour in their daily lives by repeatedly collecting data in an individual's normal environment, at or close to the time they carry out that behaviour
Study NCT04312165 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Duramesh Laparotomy Closure
Description: Closure of midline laparotomy incision with experimental suture
Study NCT04312165 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional suture closure
Description: Closure of midline laparotomy incision with standard suture
Study NCT04862572 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI scanning
Description: In the audiological assessment, participants will undergo various audiometric test, such as pure tone audiometry with extended high-frequency range, speech audiometry, tympanometry, and auditory reflex threshold. These tests are all noninvasive and aim to assess participants hearing threshold, speech-in-noise difficulty, whether or not they have conductive hearing loss, and test efferent auditory function. The appointment will take around 60-90 minutes. An experienced audiologist on-site will be in charge of this procedure.~In the MRI appointment, participant will undergo MRI scanning. Before the MRI scan, a researcher with experienced radiographer will re-check that the participant is safe to be scanned, with the standard University of Nottingham safety questionnaire. This rechecking step is necessary to make sure that participants are still eligible for the scanning. An experience radiographer will be in charge of this procedure.
Study NCT04814875 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ATX-101 + Carboplatin + Pegylated liposomal doxorubicin (ACD)
Description: Pegylated liposomal doxorubicin (30 mg/m²) will be administered intravenously on Day 1 of each 28-day cycle; carboplatin (AUC5) will be administered intravenously on Day 1 of each cycle.~ATX-101 will be administered intravenously on Day 2 of each cycle in three escalation cohorts: 20, 30, and 45 mg/m² according to a 3+3 design.
Study NCT05552274 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ECC4703
Description: ECC4703 will be administered as 1 mg, 10 mg and 40 mg capsules. ECC4703 will be administered as oral capsules during each dosing day.
Study NCT05552274 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching Placebo will be administered as oral capsules. Matching Placebo will be given orally during each dosing day.
Study NCT05405556 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: eGFR reporting
Description: To test the proportion of patients successfully completing the protocol according to different eGFR reporting strategies, randomization in a 1:1 fashion at the patient level (n=50) will occur as follows:~1. only study-related eGFR values >25% below baseline will be reported to patients and providers~2. all study-related eGFR will be provided to patients and providers
Study NCT05405556 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: eGFR reporting
Description: To test the proportion of patients successfully completing the protocol according to different eGFR reporting strategies, randomization in a 1:1 fashion at the patient level (n=50) will occur as follows:~1. only study-related eGFR values >25% below baseline will be reported to patients and providers~2. all study-related eGFR will be provided to patients and providers
Study NCT06023407 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Water Immersion Heat Therapy
Description: 10-weeks of 3 days per week in 1 of the 2 arms
Study NCT06023407 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Water Immersion Heat Therapy
Description: 10-weeks of 3 days per week in 1 of the 2 arms
Study NCT05574985 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)
Description: Injected one dose of research vaccine
Study NCT05574985 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Inactivated COVID-19 vaccine (Vero Cell)
Description: Injected one dose of control vaccine
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Intensity Laser Therapy
Description: HILT is applied per session, with a maximum of 10.0 W, a mean of 5.7 W, a dose of 99 J/cm², and a total energy flux of 2079 J were applied over 6 minutes and 5 seconds on a 21 cm² field on the medial aspect of the knee joint.
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Transcutaneous Electrical Nerve Stimulation
Description: TENS is an analgesic modality of physical therapy
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Transcutaneous Electrical Nerve Stimulation
Description: TENS is an analgesic modality of physical therapy
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Hotpacks
Description: Hotpacks is a thermoanalgesia modality of physical therapy
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hotpacks
Description: Hotpacks is a thermoanalgesia modality of physical therapy
Study NCT06549543 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: SHAM - High Intensity Laser Therapy
Description: for control group, sham HILT was applied, with lights on but no laser beam
Study NCT06051708 — intervention group
Intervention type: OTHER
Intervention: standard AKI care bundle
Description: AKI care bundle include use of iv fluids, diuretics, antihyperkalemic drugs, sodium bicarbonate, antibiotics in septic patients.
Study NCT06051708 — intervention group
Intervention type: OTHER
Intervention: standard care for hospitalized patients
Description: this includes iv fluids, diuretics, antibiotics in septic patients, other measures according to original disease
Study NCT06416995 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: first trimester serum diagnostic test
Description: First trimester serum vasohibin-1, vasohibin-2, cardiotropin-1 and endocan concentrations predict adverse perinatal outcomes
Study NCT06364293 — intervention group
Intervention type: OTHER
Intervention: Observational design does not include interventional behavior.
Description: Observational design does not include interventional behavior.