AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06079762 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AGE SELF CARE group visit program
Description: AGE SELF CARE: Adaptation, Growth, and Engagement; Socialization, Empowerment, Learning, and Function; and Community Activation for Resilience in Elderhood, is a virtual group visit program. It includes education and behavioral change elements in the broad areas of self/health, home environment, and community. There are 8 weekly 90-minute virtual sessions facilitated by an aging expert (e.g., geriatrician). Examples of topics include Aging Well: The Power of Movement, People Can Change, Homes Can Too, and Social World.
Study NCT06494306 — intervention group
Intervention type: BEHAVIORAL
Intervention: European Test of Olfactory Capabilities (ETOC)
Description: Investigators will collect the ETOC score in patient of both arms
Study NCT06494306 — intervention group
Intervention type: BEHAVIORAL
Intervention: Standardized Hedonicity Test
Description: To smell 20 odorant solutions and for each odor and evaluate it along five dimensions: familiarity, hedonicity, edibility, desire to smell again, perceived intensity). Each dimension is assessed with a Likert scale (from 1 (not at all) to 9 (extremely))
Study NCT06494306 — intervention group
Intervention type: BEHAVIORAL
Intervention: Questionnaires
Description: Patients with PTSD will have the following questionnaires : PTSD Checklist for Diagnostic and Statistical Manual (DSM)-V (PCL-5), Peri-trauma Dissociation Experience Questionnaire (PDEQ), Patient Health Questionnaire-9 (PHQ9), Snaith-Hamilton Pleasure Scale (SHAPS), Childhood Trauma Questionnaire (CTQ) and Apathy Evaluation Scale (AES)
Study NCT06494306 — intervention group
Intervention type: BEHAVIORAL
Intervention: Odor / trauma association questionnaire
Description: Patients with PTSD will have Odor / trauma association questionnaire
Study NCT05265156 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Plant based formula for children aged between 12 and 36 months
Description: Daily intake of plant based formula for 3 weeks (400ml-600ml per day).
Study NCT06273475 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Robot-assisted Training
Description: Gait training and functional strength training facilitated by body weight unloading robotic technology yielding a dynamic unloading force applied to the body centre of mass. Gait training will be conducted both on treadmill and overground. Functional strength training exercises include sit-to-stand, stair-walking, step-ups etc. The goal is to gradually reduce body weight unloading as participants progress through the intervention period.
Study NCT06273475 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Training
Description: Gait training and functional strength training facilitated without the use of body weight unloading robotic technology, thereby only allowing manual assistance from physiotherapists. The goal of training is the same as in the intervention group, however no body weight unloading device will be implemented in the active control group.
Study NCT06372418 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breastfeeding peer support intervention
Description: In addition to support as currently recommended by the World Health Organization (WHO) and National IMAM guidelines, care givers will receive a homebased individualized face to face support provided by breastfeeding peer supporters and phone call support upto 7 weeks post hospital discharge.
Study NCT06372418 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Care
Description: Caregivers will receive post-discharge support as currently recommended by the World Health Organization (WHO) and national IMAM guidelines.
Study NCT04823793 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Stool DNA methylation detection
Description: Stool specimens are collected from participants in the outpatient department or the inpatient department. Both FIT and stool DNA real-time PCR are performed simultaneously. To improve the sensitivity and specificity of the colorectal cancer screening, this study enrolls multiple candidate genes to distinguish whether the participant has a high risk of colorectal cancer.
Study NCT06015620 — intervention group
Intervention type: PROCEDURE
Intervention: Mini gastric bypass surgery
Description: Mini gastric bypass surgery is a common metabolic or bariatric surgery done world wide for patients suffering from morbid obesity not managed by non surgical modalities of treatment.
Study NCT05509283 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Risk Reduction
Description: Letter, patient portal, SMS and/or another modality
Study NCT04750577 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo matching BI 685509
Description: film-coated tablet
Study NCT04750577 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 685509
Description: film-coated tablet
Study NCT06646224 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CorVad Percutaneous Ventricular Assist System
Description: The CorVad Percutaneous Ventricular Assist System provides circulatory support for patients with cardiogenic shock.
Study NCT05218421 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Carotid ultrasound
Description: Carotid ultrasound with flow and elastography (strain and shear wave) measurements will be performed maximally 2 weeks prior to the CEA. Ultrasound-based flow imaging will be repeated six weeks after the CEA to assess the hemodynamic consequences of the CEA procedure.
Study NCT05218421 — intervention group
Intervention type: OTHER
Intervention: Biospecimen collection and examination
Description: The plaque excised during CEA will be histologically examined to assess the plaque composition, and therefore plaque vulnerability.
Study NCT05218421 — intervention group
Intervention type: OTHER
Intervention: Blood sample collection
Description: In the first 20 included patients in the Radboudumc, a 10 mL blood sample will be collected during surgery via the arterial line that is applied for regular care.
Study NCT06385197 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: App randomizing dosing regimen
Description: patients will receive their dimethyl fumarate treatment and the dose and time of administration will be determined using a designated app.
Study NCT04836481 — intervention group
Intervention type: OTHER
Intervention: Serum Sample Collection
Description: Each patient will have 5 serum samples collected for analysis after a minimum six consecutive doses. Patients receiving LEV8 will have sampled collected at hours 0.5, 1, 4, 6, and 8. Patients receiving LEV12 will have sampled collected at hours 0.5, 1, 4, 8, and 12.
Study NCT04789928 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gentamicins-EDTA
Description: Patients included in this study will receive daily injection (up to 10 days) of genta-EDTA-Na2 lock associated with systemic antibiotics.
Study NCT05046431 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAT2506
Description: 50mg/0.5mL
Study NCT05046431 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: EU Simponi
Description: 50mg/0.5mL
Study NCT05990959 — intervention group
Intervention type: OTHER
Intervention: No intervention for research purpose
Description: No any intervention will be applied under research purpose. All procedure or drugs would be given to the patient under best clinical judgment, not for research purpose.
Study NCT05479591 — intervention group
Intervention type: DRUG
Intervention: IDegLira
Description: Participants will be treated with IDegLira at the treating physician's discretion according to the approved IDegLira label in Croatia and independent from the decision to include the participant in the study.
Study NCT05648240 — intervention group
Intervention type: OTHER
Intervention: Blood test
Description: Venous blood samples taken at the moment of colonoscopy to test for biomarkers
Study NCT06472999 — intervention group
Intervention type: PROCEDURE
Intervention: Nephroprotective measures
Description: Due to the observational design of the study, no study specific interventions are performed. The treatment of the patients is completely guided by the responsible physicians.
Study NCT06286475 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VRG50635
Description: Specified dose on specified days
Study NCT06286475 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Specified dose on specified days
Study NCT05814705 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Protein supplement
Description: Ready-to-drink protein beverage consumed once daily for 28 days
Study NCT05814705 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein supplement with Urolithin A
Description: Ready-to-drink protein beverage with 1000 mg of Urolithin A consumed once daily for 28 days
Study NCT06389149 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LEAP therapy
Description: Knee bending from 90°-180° at 1Hz for 1 minute every 10 minutes during 2.5 hours of prolonged sitting
Study NCT06389149 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: no LEAP therapy
Description: 2.5 hours of uninterrupted prolonged sitting (no movement)
Study NCT04116723 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flexible brace
Description: Participants will be invited to undergo a fitting session of a flexible brace. After the fitting session, participants will join a two-hours wear trial of the flexible brace. Participants are required to wear the brace for two-hours and undergo assessments before and after the wear trial. The measurement outcomes of the assessment include 1) X-ray scan, 2) 3D body scan, 3) garment pressure, and 4) questionnaire.
Study NCT06057714 — intervention group
Intervention type: COMBINATION_PRODUCT
Intervention: 19F MRI
Description: Inhalation of a biologically inert contrast gas, perfluoropropane, combined with 19F-tuned MRI with image acquisition at breath-hold and during tidal breathing
Study NCT04159168 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Facial Affect Sensitivity Training (FAST)
Description: The FAST intervention program represents a novel computerized intervention for high-risk youth that strategically targets implicated facial affect sensitivity deficits directly via a computerized real-time automated feedback and incentive system to remediate callous-unemotional tendencies associated with behavioral dysfunction.
Study NCT04159168 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Implicit Gaze Training task (Active control condition)
Description: This computerized task was developed to target implicit training of eye gaze but not facial emotion recognition per se via real-time feedback and incentives. On each trial, a fixation cross is followed by an emotional face with eyes directed either left, straight ahead, or right (balanced across expressions), followed by a response key. The child's task is to say which direction the eyes are looking (e.g., 1 or left). Stimuli are black and white standardized photographs of men and women models from the Ekman Pictures of Facial Affect each displaying the 3 gaze directions for 6 emotion expressions.
Study NCT06022042 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: On1 two-stage abutment and one-stage abutment
Description: the On1 two-stage abutment has a smooth collar with a height of 1.75-2.5mm, and the Nobel implants have a smooth neck design ranging from 0-0.75mm to protect the connective tissue around the implant.
Study NCT06022042 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: On1 two-stage abutment and one-stage abutment
Description: the On1 two-stage abutment has a smooth collar with a height of 1.75-2.5mm, and the Nobel implants have a smooth neck design ranging from 0-0.75mm to protect the connective tissue around the implant.
Study NCT05768191 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: premix insulin human isophane suspension and insulin human
Description: Sequence (Premix first, then Humulin N + Humulin R): Subjects randomized to this sequence will receive premix insulin, twice per day for 16 weeks. After the first 16 weeks, subjects will cross over to the Humulin N plus Humulin R sequence for a further treatment of 16 weeks
Study NCT05768191 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Humulin N plus Humulin R
Description: Sequence (Humulin N + Humulin R first, then Premix): Subjects randomized to this sequence will receive basal bolus insulin scheme with Humulin N (twice daily) and Humulin R (before meals) for 16 weeks. After the first 16 weeks, subjects will cross over to the Premix sequence for a further treatment of 16 weeks
Study NCT05572177 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Asthma SMART
Description: The intervention is a smartphone application to improve self-management of asthma designed to appeal to adolescents. The app integrates four components to facilitate asthma self-management: 1) self-monitoring of peak-flow and symptoms; 2) graphical health user interfaces with avatars, infographics, and rewards; 3) interactive educational materials; and 4) patient-provider interactions.
Study NCT06219161 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: NAD3
Description: NAD3 supplement (per capsule): 344 mg microcrystalline cellulose,156 mg of a proprietary blend of Wasabia japonica (freeze-dried rhizome) cultivar, standardized to NLT 12,000 ppm isothiocyanates, 97.0% Theacrine, Copper Nicotinic Acid chelated complex (17-20% Copper by ICP-Mass spectroscopy)
Study NCT06219161 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: NAD3
Description: NAD3 supplement (per capsule): 344 mg microcrystalline cellulose,156 mg of a proprietary blend of Wasabia japonica (freeze-dried rhizome) cultivar, standardized to NLT 12,000 ppm isothiocyanates, 97.0% Theacrine, Copper Nicotinic Acid chelated complex (17-20% Copper by ICP-Mass spectroscopy)
Study NCT06170229 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: eHIIT
Description: Education and High intensity Interval Training (Aerobic Exercise)~The focus of the one educational session is rationale for aerobic exercise, expected physiological effects of aerobic exercise, diet when performing an exercise program, how the knee accommodates to exercise (including potential experience of muscle soreness and how that is different from joint pain), and management of potential knee OA symptom flares.~HIIT is an aerobic exercise form. The eHITT protocol consist of eight 2-minute intervals of high intensity training (with the goal to train at a heart rate of at least 80% of HRmax) followed by 2 minutes of moderate training intensity (with the goal to train at a heart rate of at least 60% of HRmax).~There will be several types of exercise modalities for aerobic exercise available (treadmills, cross-trainers, row- and cycle ergometers) and participants may choose whichever they prefer.
Study NCT06170229 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: NEMEX-e
Description: Education and Neuromuscular Exercise~The focus of the two educational sessions is on providing knowledge of OA and treatment options to the participants, with a special focus on knee OA, diet, and exercise and its benefits. Furthermore, advice about self-management is given.~The exercises are based on neuromuscular principles to improve sensorimotor control and achieve compensatory functional stability. Sensorimotor control is the ability to coordinate muscle activity and maintain functional stability during movement allowing for joint stability during physical activity. Various positions (sitting, lying, standing) are used to achieve the desired postural activity. The overall goal is to obtain muscle control and stability in situations resembling daily life and/or more strenuous activities. The focus is on achieving good quality of the performance in each exercise with appropriate postural orientation (e.g., joint positioned appropriately in relation to each other).
Study NCT05481398 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Negative Pressure Wound Therapy
Description: The wound is dressed using negative pressure wound therapy comprising of a single layer of sterile gauze followed by placement of a 18 Fr nelaton catheter and the wound further covered with 4 more layers of sterile gauze over the nelaton catheter. The wound is then covered with opsite dressing making it airtight. The nelaton catheter is attached to the wall suction port once the patient is shifted to the bed with pressure set at - 25 mm Hg.
Study NCT05055934 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1314 injection
Description: SHR-1314 injection
Study NCT05055934 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo
Study NCT05253079 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: subcostal transversus plane block
Description: Patient in TAP block group will receive oblique subcostal TAP while in supine position using a linear 6-13 MHz ultrasound transducer. The operator will place the ultrasound probe obliquely on the upper abdominal wall along the subcostal margin near the xiphisternum of the sternum in the midline of the abdomen. The landmarks, which included the rectus abdominis muscle and underlying transversus abdominis muscle, will be identified near the costal margin and xyphoid. The probe will be then moved laterally until the aponeurosis of the external, internal oblique, and transversus abdominis are seen, and then the probe will be moved further laterally until the transversus abdominis muscle is identified. The operator will direct the needle toward the transversus abdominis, and the local anesthetic solution will be injected after negative aspiration between the rectus abdominis and transversus abdominis muscles along the subcostal line (in-plane superomedial to inferolateral)
Study NCT05253079 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: erector spinae plane block
Description: Patients in ESPB group will be turned to the lateral position and receive ESPB at the level of the 7th thoracic (T7) transverse process using a linear 6-13 MHz ultrasound transducer. The transducer will be positioned vertically 3 cm to the side of the midline to visualize the muscles of the back, the transverse process, and the pleura between the two transverse processes. Then, a 22G 10-mm needle will be introduced in the cranial-caudal direction toward the transverse process (T7) using the in-plane method till the needle tip crosses all the muscles. The tip of needle should be in the plane between the transverse process and the erector spinae muscle. After ensuring negative aspiration, the local anesthetic solution will be injected below the muscle. the procedure will be repeated on the other side
Study NCT05365269 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Proactive Automatized Lifestyle intervention
Description: Multi-behavioral; including individually-tailored, theory-based, repetitive, ipsative and normative feedback.
Study NCT05742893 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Measurement of pragmatic and discourse test scores in the two scales.
Description: The aim of this study is to compare the effectiveness of a newly developed speech-language assessment tool for pragmatic and discourse skills for patients suffering from schizophrenia .
Study NCT06543550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Implantable gestrinone
Description: 1.6mg/kg of weight of gestrinone in pellets (bio meds Brasil, Florianópolis, Brazil) subcutaneously, in the gluteal region.
Study NCT06543550 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oral Dienogest
Description: Administered orally at 2 mg daily
Study NCT04795076 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Infant formula
Description: Regular infant formula will be concentrated to give a calorie density of about 90 kcal/100 mL.
Study NCT05862883 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rutan 25 mg
Description: Active ingredient: (3,6-bis-O-galloyl-1,2,4-tri-O-galloyl-β-D-glucose). Active substance: Rutan 25 mg. Excipients: potato starch, calcium stearate, lactulose.
Study NCT05862883 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control group
Description: Taking basic therapy without Rutan
Study NCT05159102 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 12-week FMS Intervention
Description: 4 sessions, no more than 3 hours per session covering 1) Sensory Integration, 2) Communication, 3) Physical activity, and 4) and Sports (during intervention)
Study NCT05159102 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activities & Activity Booklets (via FitFamilies app)
Description: expected to engage in physical activity at least 3 hours per week, parent workshops provide them with resources to engage in Physical activity
Study NCT05159102 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Physical Activities & Activity Booklets (via FitFamilies app)
Description: expected to engage in physical activity at least 3 hours per week, parent workshops provide them with resources to engage in Physical activity
Study NCT04795076 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Infant formula
Description: Regular infant formula will be concentrated to give a calorie density of about 90 kcal/100 mL.
Study NCT06288256 — intervention group
Intervention type: OTHER
Intervention: No Intervention
Description: No Intervention
Study NCT05122793 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prevention offer
Description: Improvement of outcomes through lifestyle changes and improved health literacy
Study NCT06327685 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Avapritinib
Description: Avapritinib is an oral tyrosine kinase inhibitor.
Study NCT06327685 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: Decitabine is a nucleoside metabolic inhibitor given intravenously.
Study NCT06327685 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Decitabine/Cedazuridine
Description: Decitabine/Cedazuridine is a combination medicine given orally.