AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Indirect calorimetry test
Description: Both resting metabolic rate and respiratory quotient will be measured after a 10-hour fast by indirect calorimetry. The test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Indirect calorimetry test
Description: Both resting metabolic rate and respiratory quotient will be measured after a 10-hour fast by indirect calorimetry. The test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Well-being questionnaire
Description: Participants will be asked to complete a well-being questionnaire (nausea, fatigue, etc) during visits 2, 3 and 4.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Well-being questionnaire
Description: Participants will be asked to complete a well-being questionnaire (nausea, fatigue, etc) during visits 2, 3 and 4.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Diet appreciation questionnaire
Description: Participants will be asked to complete a diet appreciation (appetite, fullness, etc) questionnaire during visits 3 and 4.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet appreciation questionnaire
Description: Participants will be asked to complete a diet appreciation (appetite, fullness, etc) questionnaire during visits 3 and 4.
Study NCT04758858 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Pedometer (PiezoRxD)
Description: Participants will be asked to wear a pedometer (PiezoRxD) that will record their steps every day during the whole trial. Also, they will have to install Piezo: Achieve the Guidelines!, a free mobile application, on their smartphone or tablet. It will connect to their pedometer via bluetooth and will help the research assistant track their data remotely
Study NCT04758858 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pedometer (PiezoRxD)
Description: Participants will be asked to wear a pedometer (PiezoRxD) that will record their steps every day during the whole trial. Also, they will have to install Piezo: Achieve the Guidelines!, a free mobile application, on their smartphone or tablet. It will connect to their pedometer via bluetooth and will help the research assistant track their data remotely
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Hepatic imaging (MRI)
Description: Imaging of participants' liver will be done by MRI at the Centre Hospitalier de l'Université de Montréal (CHUM). The test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hepatic imaging (MRI)
Description: Imaging of participants' liver will be done by MRI at the Centre Hospitalier de l'Université de Montréal (CHUM). The test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Glucagon efficiency test
Description: The glucagon efficiency test will be done twice, before (visit 2) and after (visit 4) the intervention phase. A subcutaneous insulin injection based on individual insulin correction factor will be given to induce hypoglycemia down to 3 mmol/L (based on plasma glucose). A subcutaneous injection of 300 µg of glucagon will be administered.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Glucagon efficiency test
Description: The glucagon efficiency test will be done twice, before (visit 2) and after (visit 4) the intervention phase. A subcutaneous insulin injection based on individual insulin correction factor will be given to induce hypoglycemia down to 3 mmol/L (based on plasma glucose). A subcutaneous injection of 300 µg of glucagon will be administered.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Body composition : Dual Energy X-ray absorptiometry (DEXA)
Description: Lean body mass and fat mass will be measured by Dual Energy X-ray absorptiometry (DEXA). The DEXA test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Body composition : Dual Energy X-ray absorptiometry (DEXA)
Description: Lean body mass and fat mass will be measured by Dual Energy X-ray absorptiometry (DEXA). The DEXA test will be done twice, before (visit 2) and after (visit 4) the intervention phase.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Blood tests
Description: Blood tests will be done to assess participants' diabetes control as well as to assess other biochemical markers (blood lipids as well as markers of inflammation and liver function). Blood will be collected and analyzed during all visits (visits 1 to 4).
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood tests
Description: Blood tests will be done to assess participants' diabetes control as well as to assess other biochemical markers (blood lipids as well as markers of inflammation and liver function). Blood will be collected and analyzed during all visits (visits 1 to 4).
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Stool sample collections (optional)
Description: Participants will be asked to collect and immediately freeze their stool sample until it is given to the study team (for intestinal microbiota composition analysis). This will be done three times during the study, during phase 1, between week 1 and 6 of phase 2 and between week 6 and 12 of phase 2.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stool sample collections (optional)
Description: Participants will be asked to collect and immediately freeze their stool sample until it is given to the study team (for intestinal microbiota composition analysis). This will be done three times during the study, during phase 1, between week 1 and 6 of phase 2 and between week 6 and 12 of phase 2.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Hypoglycemia journal
Description: During the whole trial, participants will be asked to keep a log of their hypoglycemia episodes, which are defined by the need to consume CHO. They will be asked to note the time, symptoms (including time taken for disappearance after treatment), capillary glucose measurement and the amount of CHO consumed.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hypoglycemia journal
Description: During the whole trial, participants will be asked to keep a log of their hypoglycemia episodes, which are defined by the need to consume CHO. They will be asked to note the time, symptoms (including time taken for disappearance after treatment), capillary glucose measurement and the amount of CHO consumed.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Ketone journal
Description: During the intervention phase, participants will be asked to measure their ß-hydroxybutarate level (mmol/L) with their Abbott's Freestyle-Libre scanner at least twice per week before breakfast. Participants will be asked to check their ketone bodies for sensor or capillary glucose levels exceeding 15 mmol/l, when their sensor indicates high without a specific glucose value and when they have symptoms of ketoacidosis (regardless of glucose reading).
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Ketone journal
Description: During the intervention phase, participants will be asked to measure their ß-hydroxybutarate level (mmol/L) with their Abbott's Freestyle-Libre scanner at least twice per week before breakfast. Participants will be asked to check their ketone bodies for sensor or capillary glucose levels exceeding 15 mmol/l, when their sensor indicates high without a specific glucose value and when they have symptoms of ketoacidosis (regardless of glucose reading).
Study NCT05973578 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: Stereotactic radiotherapy
Description: Single-session high dose stereotactic radiotherapy
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Adherence to the diet (Keenoa)
Description: During the whole dietary intervention phase (phase 2), participants will confirm that they have followed their menus by taking before and after pictures of their meals every day and indicating the percentage of their meal consumed (25-50-75-100%) via the Keenoa mobile application.
Study NCT04758858 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Adherence to the diet (Keenoa)
Description: During the whole dietary intervention phase (phase 2), participants will confirm that they have followed their menus by taking before and after pictures of their meals every day and indicating the percentage of their meal consumed (25-50-75-100%) via the Keenoa mobile application.
Study NCT06358521 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physiotherapist-led primary care model for hip and knee pain
Description: 1. Initial assessment and screening: The PT will provide a comprehensive assessment according to established clinical practice guidelines.~2. Brief individualized intervention at first visit: The PT intervention will be at the discretion of the PT to reflect real-world PT intervention.~3. Health services navigation: Participants will be provided with options available to them in their community for rehabilitation. For example, they may be referred to community PT for ongoing management. Participants will be assessed regarding the need for specialist referrals or resources available to manage complex clinical presentations. Participants may be referred to the primary care provider if no specialized services are needed or when the PT cannot provide a direct referral.~4. Additional PT care: Patients who require community PT but do not have the appropriate coverage for community-based services will be managed by the PT who provided the assessment in the primary care setting.
Study NCT06358521 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual physician-led primary care model for hip and knee pain
Description: The physician led primary care intervention will be unstandardized to best reflect standard clinical practice in Canada.
Study NCT06070337 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: H-Guard
Description: A novel Haemodialyser primer used for one treatment only
Study NCT06176391 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Spinal Cord Stimulation
Description: Single lead placement in the posterior thoracic epidural space (T1-T4) connected to a subcutaneous battery
Study NCT05580614 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: MRI (Magnetic Resonance Imaging) paired ERP/Sham YBOCs(Yale-Brown Obsessive Compulsive Scale) (4,8,12) OCI-R (every other session). YBOCs and OCI-R will also be administered at intake and 4 weeks post treatment.
Study NCT05580614 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: tVNS
Description: MRI (Magnetic Resonance Imaging) paired ERP/tVNS YBOC's (Yale-Brown Obsessive Compulsive Scale) (4, 8, 12) OCI-R (every other session). YBOCs and OCI-R will also be administered at intake and 4 weeks post treatment.
Study NCT05343988 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Percutaneous Electrical Nerve Field Stimulation (PENFS) device application
Description: PENFS device will be used to treat children with paroxysmal sympathetic hyperactivity (PSH) due to acute severe brain injury.
Study NCT06457737 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IPS Empress Direct
Description: Resin composite will be heated and used to lute a ceramic partial coverage restoration.
Study NCT06457737 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bisco Duo-Link Universal
Description: Dual cure adhesive resin cement will be used to lute a ceramic partial coverage restoration.
Study NCT05560789 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity (cycling on a stationary bicycle ergometer or walking on a treadmill)
Description: At time 0, exercise will be initiated and intensity will be increased at 2 minute intervals to achieve low intensity for 30 minutes (as defined by heart rate target 50-55% of maximum heart rate determined as 220-age). Next, intensity will be increased at 2 minute intervals until the heart rate target for moderate intensity exercise is achieved (55-65% of max heart rate), or the total duration of exercise of up to 60 minutes is achieved.
Study NCT05033912 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CST-2032, matching placebo for CST-2032, CST-107
Description: CST-2032 and matching placebo oral liquid; CST-107 white capsules
Study NCT04293978 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CalmPlace
Description: Self-contained VR application allowing the user to build and custom a relaxation session, with options to vary session length (9-20 minutes), music/sound, relaxation exercises, and specific nature environment (three available) including time of day and events (e.g. rain). Delivered using an Oculus Go devices in kiosk-mode.
Study NCT06181799 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Mass spectrometry using the PTR TOF-1000 (IONICON PTR-TOF-MS - Trace VOC Analyzer, Eduard-Bodem-Gasse 3, 6020 Innsbruck, Austria (Europe).
Description: Once enrolled in the study, all participants are scheduled to undergo the following tests:~The analysis of volatile organic compounds obtained from exhaled air will be carried out by a combination of real-time analytical methods, the use of a real-time mass spectrometer with ionization by the proton transfer method. Machine learning models will be employed to analyze the patterns identified in the exhaled air volatilome data.~Before and immediately after the exercise test, all patients are scheduled to record a single-lead ECG and pulse wave, using a portable single-lead recorder (Cardio-Qvark) (Russia, Moscow). Single lead-ECG and pulse wave parameters will be interpreted using machine learning models.
Study NCT06492200 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psyllium husks
Description: Patients in the intervention group will receive nutritional counseling and will be asked to take 10g (one tablespoon) of ground psyllium husks daily to significantly increase the fiber content of their diet.
Study NCT06289803 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: probe confocal laser endomicroscopy
Description: probe confocal laser endomicroscopy will be used to identify the tumor behavior
Study NCT04594746 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amiodarone Hydrochloride
Description: Amiodarone hydrochloride 2000 mg PO to be given as a 10-capsule dose pack and ingested in a single sitting with food
Study NCT04594746 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo to be given as a 10-capsule dose pack and ingested in a single sitting with food
Study NCT05922930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TROP2-CAR-NK
Description: Given by IP (intraperitoneal)
Study NCT05922930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: Given by IV (vein)
Study NCT05922930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Given by IV (vein)
Study NCT06219252 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Intraoperative aberrometer
Description: the patient intraocular lens will be optimized during the aphakic period after cataract extraction and before intraocular lens implantation, this will produce a possible change in the dioptric power of the intraocular lens
Study NCT06219252 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Preoperative intraocular lens calculation
Description: the intraocular lens in this group will be calculated preoperatively with Barrett Universal II formula
Study NCT06119503 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Elongating Time HOrizons for Reentry (ETHoR)
Description: The adapted episodic future thinking (EFT) intervention will focus on generation of vivid, substance-free, rewarding events that could happen in an incarceration free future.
Study NCT06119503 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standardized Episodic Thinking (SET)
Description: In the standardized episodic thinking (SET) condition, the participant will instead describe in vivid details events that have occurred in the recent past.
Study NCT06654037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Abemaciclib
Description: Given PO
Study NCT06654037 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo tissue biopsy
Study NCT06654037 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT06654037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: Given IV
Study NCT06376864 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activity Breaks
Description: The Activity Breaks intervention is a 5-minute Activity Breaks programme that allows classroom teachers of all ages and ability levels to lead simple movement activities within their classrooms, negating the need for additional personnel or space.
Study NCT06007027 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy
Description: The laser probe is gently inserted up to the top of the vagina, and subsequently withdrawn and rotated in order to deliver a complete treatment of the vaginal wall.
Study NCT06007027 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy
Description: The laser probe is gently inserted up to the top of the vagina, and subsequently withdrawn and rotated in order to deliver a complete treatment of the vaginal wall.
Study NCT05278520 — intervention group
Intervention type: PROCEDURE
Intervention: Total hip arthroplasty
Description: Hip joint replacement surgery. Elective for RA and OA cases.
Study NCT06715722 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: hexed non hexed
Description: A 3-unit screw-retained implant bridge over two conical internal hex implants will be supported using one hexed and one non-hexed abutment.
Study NCT06715722 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: non-hexed non-hexed
Description: a 3-unit screw-retained implant bridge over two conical internal hex implants will be supported using two non-hexed abutments
Study NCT06715995 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
Description: Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.
Study NCT06715995 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
Description: Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.
Study NCT06719466 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: low linoleic acid (LA)
Description: diet guidance with low linoleic acid (LA) diet
Study NCT06715657 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine intrathecal
Description: patients intrathecal anaesthesia with morphine
Study NCT06715657 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Morphine intrathecal
Description: patients intrathecal anaesthesia with morphine
Study NCT06715657 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: propofol
Description: patients will receive 0.5 mg/kg propofol diluted in 10 ml saline 0.9% IV injection 15 min before the end of surgery
Study NCT06715657 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: propofol
Description: patients will receive 0.5 mg/kg propofol diluted in 10 ml saline 0.9% IV injection just before intrathecal anaesthesia
Study NCT06716684 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Approach Based Psychoeducation Program
Description: A 6 session cognitive-behavioral approach based psychoeducation program developed in line with the literature review is applied in the research. Group training sessions have been held once a week with each session 90 minutes on average. The techniques such as automatic thought recording, finding cognitive errors, thought-stopping, forming alternative thoughts, daydreaming, countdown, problem solving, role playing, modeling, deep breathing, relaxation exercises, summarizing, explaining, informing, homework were used in the sessions.
Study NCT06717373 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: AutoAS
Description: AutoAS is an artificial intelligence algorithm that will be tested retrospectively on the images acquired as part of the study
Study NCT06718192 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Bleomycin injection
Description: Wart injection (0.2 mL \<5 mm; 0.5 mL 5-10 mm; 1ml for >10 mm) were injected at a depth of 1.5mm, diluted with normal saline at a concentration of 3u/ml=3mg/ml, and the maximum amount of each wart was 1ml until the wart turned white
Study NCT06718192 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cryotherapy
Description: The wart was frozen by liquid nitrogen until a circle of frozen tissue appeared around the wart for about 10s, with an interval of 30s, for a total of 2 times