AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06436456 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Online psychological intervention
Description: The online intervention constitutes a psychological intervention rooted in therapeutic principals of Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT). Comprising 7 obligatory modules and 4 optional modules, the intervention is facilitated through an online platform, offering a text-based self-help program. Patients receive written guidance from a psychologist at Steno Diabetes Center Odense (SDCO). While undergoing intervention, patients have the option to seek clarification or assistance from the psychologist if encountered with queries or difficulties. It is anticipated that patients will progress through approximately one module per week. Following completion of the intervention, patients retain access to the online intervention for a duration of 3 months.
Study NCT06436456 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Individual psychological intervention
Description: In the individual intervention, patients undergo personalized therapy administered by the assigned psychologist from SDCO. This treatment approach is grounded in the principles of Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT). Delivery of treatment can occur through various modalities, including telephone, video conferencing, or in-person sessions, tailored to accommodate the preferences and requirements of the patient. A maximum of 10 treatment sessions are available for each patient.
Study NCT05758090 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: NIPE monitor
Description: Procedure/Surgery: NIPE protocol. Give intraoperative fentanyl according to NIPE value. NIPE score 50-70 indicates optimal narcotic effect. NIPE score > 70 indicated overdosage of narcotic and narcotic should be withheld. NIPE score \< 50 indicates inadequate narcotic and narcotic should be given.
Study NCT05758090 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Procedure/Surgery: Standard protocol. Give intraoperative fentanyl according to vital signs.
Study NCT05734729 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EFFIDRAIN
Description: . Effidrain is a progammable, light-weight, portable drain regulator that can control the rate and volume of body fluid being drained, while empowering the user with information on dynamic changes of pressure within the body cavity being drainged. It is able to adapt to existing drainage systems via a standard medical luer taper connector, and comes with a failsafe system to alert users of drainage irregularities.
Study NCT05734729 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Manual drainage system
Description: drainage systems required manual control and are unautomated; consequent unintended rapid intravascular and extravascular fluid shifts may result in clinical instability.
Study NCT05236998 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SID1903 (FDC)
Description: Single oral administration of SID1903 (FDC) after an overnight fast
Study NCT05236998 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapagliflozin and Sitagliptin
Description: Single oral administration of Dapagliflozin and Sitagliptin after an overnight fast
Study NCT05572463 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Sintilimab + IBI110
Description: IBI110 infusion in combination with Sintilimab (IBI308) infusion will be given on a Q3W schedule
Study NCT06348563 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: AGED Multiple Target Assay in Healthy Controls
Description: Analysis of blood based cfDNA/cfRNA biomarkers found at defined concentrations in participant samples that correlates to healthy controls
Study NCT06348563 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: AGED Multiple Target Assay in NAFLD Participants
Description: Analysis of blood based cfDNA/cfRNA biomarkers found at defined concentrations in participant samples that correlates to NAFLD participants (defined as simple steatosis through NASH)
Study NCT06348563 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: AGED Multiple Target Assay in Fibrosis Participants
Description: Analysis of blood based cfDNA/cfRNA biomarkers found at defined concentrations in participant samples that correlates to liver fibrosis stage (F0-F4)
Study NCT06061198 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: a virtual reality device
Description: the patient will wear a masque tht will provide a virtual reality experience using a VR Gear connected to a mobile phone through an application installed on the mobile phone
Study NCT05158634 — intervention group
Intervention type: OTHER
Intervention: Evaluations
Description: Within the scope of the study, the participants will be evaluated for 30 minutes in a single session. The participants' trunk stabilization and endurance, balance, functional mobility, upper extremity endurance, functional health and quality of life will be questioned by questionnaires, scales and tests. Evaluation will begin with a literature-supported demographic data form prepared for the participants.~Assessments to be made are listed below. Trunk Control Measurement Scale (TCMS) Pediatric Balance Scale (PBS) Time Up and Go test (TUG) Trunk Flexor Test (TFT) The Pediatric Outcomes Data Collection Instrument (PODCI)
Study NCT05344833 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isatuximab
Description: Isatuximab 10mg/kg IV Days 1,8, 15, 22 Cycle 1 (all cycles 28 days). Isatuximab 10mg/kg Days 1, 15 Cylces 2 and 3. Isatuximab 10mg/kg Day 1, Cylces 4-39.
Study NCT05344833 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Lenalidomide 15mg PO Days 1-21 Cycle 4 and can continue until disease progression.
Study NCT06238622 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1015550
Description: BI 1015550
Study NCT05520528 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language intervention with group sessions and independent tasks with emphasis on improving reading and writing skills among persons with aphasia
Description: The participants will read through a designated book incrementally across multiple weeks at home and complete reading, writing, and discussion related to weekly readings in a group setting.
Study NCT05087537 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Valve ablation
Description: Valve ablation
Study NCT05087537 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Valve ablation and bladder neck incision
Description: Valve ablation and bladder neck incision
Study NCT01132105 — intervention group
Intervention type: DEVICE
Intervention: Vestibular myogenic evoked potential analyzer
Study NCT06312891 — intervention group
Intervention type: DRUG
Intervention: Ivabradine
Description: heart rate lowering therapy
Study NCT05191160 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Soy Milk
Description: 250 mL, single-serve shelf-stable pack (Alpro Soya) 100 Kcal, 8g of soy protein
Study NCT05191160 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cow's Milk
Description: 250 mL, single-serve shelf-stable pack (Organic Meadows) 130 Kcal, 8g of casein/whey protein
Study NCT05191160 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sugar Sweetened Beverages
Description: 355 mL, single-serve cans 130-140 Kcal, 0g of protein
Study NCT06444529 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apraclonidine Hydrochloride Ophthalmic Solution
Description: Investigational ophthalmic solution applied topically to the eye with a dropper bottle
Study NCT06444529 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Vehicle (inactive ingredients) applied topically to the eye with a dropper bottle
Study NCT03883139 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: JASPER
Description: JASPER is a developmentally anchored behavioral intervention that assumes that communication develops from social interactions in which specific social engagement strategies, symbolic representations, and early communication forms are modeled and naturally reinforced by the adult's responses to the child.
Study NCT05512871 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personalized mHealth intervention to promote short-term metabolic and mental health among women with a history of Gestational Diabetes Mellitus (GDM)
Description: The study aim to conduct lifestyle intervention trials to examine the feasibility, efficacy, and cost-effectiveness of the mHealth approach in preventing them from developing Type 2 Diabetes in the future. This pilot study will primarily aim to determine the feasibility of our intervention approaches as well as enhance health literacy and promote healthy lifestyle in the study participants. In the longer term, we hope that the proposed mHealth intervention can be translated to include women from the community setting and involve wider healthcare setting to come together and reduce the burden of Type 2 Diabetes in Singapore.
Study NCT05512871 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Personalized mHealth intervention to promote short-term metabolic and mental health among women with a history of Gestational Diabetes Mellitus (GDM)
Description: The study aim to conduct lifestyle intervention trials to examine the feasibility, efficacy, and cost-effectiveness of the mHealth approach in preventing them from developing Type 2 Diabetes in the future. This pilot study will primarily aim to determine the feasibility of our intervention approaches as well as enhance health literacy and promote healthy lifestyle in the study participants. In the longer term, we hope that the proposed mHealth intervention can be translated to include women from the community setting and involve wider healthcare setting to come together and reduce the burden of Type 2 Diabetes in Singapore.
Study NCT05222633 — intervention group
Intervention type: DRUG
Intervention: Ranibizumab
Description: Ranibizumab 0.5mg/0.05ml intravitreal injection
Study NCT03883139 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: DTT (Discrete Trial Training)
Description: DTT is an adult-led, highly structured, behavioral teaching approach, is considered to have the strongest evidence as a standard of care for young children with autism. DTT emphasizes didactic, adult-led instruction.
Study NCT05067764 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Aponeurectomy with grafting
Description: The lipofilling is performed, once the incisions are closed and is performed with the Puregraft® system.~The fat graft is taken from the posterior, medial and anterior sides of the arm, by skin puncture. Approximately 10 cc are harvested, allowing a reinjection of about 2 cc per digital radius treated. After conditioning, the fat graft is redistributed to the curettage areas through the skin incisions.
Study NCT05067764 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Aponeurectomy alone
Description: The patient is installed in dorsal decubitus position and the arm to be treated is anesthetized by axillary block. The procedure is performed in the operating room, respecting all the rules of asepsis and safety in force. A tourniquet is placed on the arm to be treated and inflated to 250mmHg. Broken incisions are then made opposite the cords to be excised, which are located by palpation. Once the noble elements have been identified, the excision of the cords and fibrous nodules can be done as completely as possible. Sometimes an arthrolysis procedure is necessary in order to restore extension to a joint that has been fixed in a flexion position for several years. Skin closure is most often possible by direct suture or by means of local fatty skin flaps. In some cases, the surgeon may use total skin grafts, or directed healing in certain areas where direct skin suture is not possible.
Study NCT05222633 — intervention group
Intervention type: DRUG
Intervention: Aflibercept
Description: Aflibercept 2.0mg/0.05ml intravitreal injection
Study NCT05222633 — intervention group
Intervention type: DRUG
Intervention: Conbercept
Description: Conbercept 0.5mg/0.05ml intravitreal injection
Study NCT05587751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spirometry
Description: Pulmonary function test to measure lung function
Study NCT05587751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Plethysmography
Description: Pulmonary function test to measure lung volume
Study NCT04622943 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: firearms safety
Description: interactive and engaging website with videos and educational games to teach children firearms, hunting and shooting safety
Study NCT04622943 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: nutrition
Description: interactive and engaging website with videos and educational games to teach children about nutrition and exercise
Study NCT05034822 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ruxolitinib cream
Description: Ruxolitinib 1.5% cream applied twice daily.
Study NCT05030688 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Postoperative analgesia management
Description: Intravenous 0.5 mg/kg tramodol and 400 mg ibuprofen will be administered to all patients 30 minutes before the end of the surgical procedure. In the postoperative period, patients will be administered ibuprofen iv 400 mg 3x1. If the NRS score is ≥ 4, 0.5 mg kg-1 iv meperidine will be administered as a rescue analgesic.
Study NCT05149170 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 monoclonal antibody
Description: inductive Anti-PD-1 antibody + concurrent Anti-PD-1 antibody with RT
Study NCT05401266 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: mild hypercapnia
Description: Ventilation parameters were adjusted to achieve and maintain ETCO2 50-55 mmHg until spontaneous respiration was restored
Study NCT05919706 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Education with Game-Based Mobile Technology and Motivational Interviewing
Description: Education program, game-based mobile technology and motivational interview were applied to the patients in the experimental group. The patients' self-management, quality of life, and satisfaction level scores for the intervention were determined.
Study NCT03899701 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PEC I and PEC II blocks
Description: Participants will get a PEC I block with 10ml of 0.375% ropivacaine and a PEC II block with 20ml of 0.375% ropivacaine using ultrasound guidance.
Study NCT06496373 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Personalized tumor preventive vaccines
Description: Personalised mRNA vaccine combined with PD-1 inhibitor treatment every 3 weeks, 3 weeks as a treatment cycle, a total of 13 cycles.
Study NCT05299073 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MB09
Description: Single dose of 35mg SC administered
Study NCT05299073 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: US-sourced Xgeva
Description: Single dose of 35mg SC administered
Study NCT05299073 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: EU-sourced Xgeva
Description: Single dose of 35mg SC administered
Study NCT05587283 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental: Low dose LABTHERA-001 capsule
Description: Low dose LABTHERA-001 capsule, 0.2 x 10\^9 CFU/capsule with excipients.
Study NCT05587283 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental: Medium dose LABTHERA-001 capsule
Description: Medium dose LABTHERA-001 capsule, 1 x 10\^9 CFU/capsule with excipients.
Study NCT05587283 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Experimental: High dose LABTHERA-001 capsule
Description: High dose LABTHERA-001 capsule, 5 x 10\^9 CFU/capsule with excipients.
Study NCT05587283 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Low dose Placebo capsule
Description: Medium dose Placebo capsule, filled with excipients; Lactose, and magnesium stearate.
Study NCT05587283 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: Medium dose Placebo capsule
Description: Medium dose Placebo capsule, filled with excipients; Lactose, and magnesium stearate.
Study NCT05587283 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator: High dose Placebo capsule
Description: High dose Placebo capsule, filled with excipients; Lactose, and magnesium stearate.
Study NCT04958538 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Methylprednisolone 2 mg/kg/day MTX (5-10 mg/day) was given on days 1, 3, and 8, and repeated weekly until aGVHD was less than grade II
Study NCT06087757 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Open Label Clemastine with a blinded randomize withdrawal
Description: Clemastine will be given in doses as the maximum dose recommended for allergy condition. Age 6-12 years 4.02 mg/day, age 12-30 years 8.04 mg/day.
Study NCT04804592 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Tactile Esthesiometer Prototype
Description: A round plastic nozzle (1.8mm diameter) used as a stimulus for corneal sensation threshold measurement
Study NCT04804592 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Liquid Jet Esthesiometer Prototype
Description: Balanced salt solution with a pH value similar to the tear film uesd as a liquid jet stimulus for corneal sensation threshold measurement
Study NCT04804592 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cochet Bonnet esthesiometer
Description: A nylon thread (0.12mm diameter) used as a stimulus for corneal sensation threshold measurement
Study NCT04738357 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HSK21542
Description: HSK21542：1 µg/kg
Study NCT04738357 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05065398 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HLX208
Description: 450mg bid, take orally
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin
Description: 40 mg non-enteric-coated tablet taken twice daily.
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Aspirin
Description: 40 mg non-enteric-coated tablet taken twice daily.
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Aspirin Placebo
Description: non-enteric-coated tablet taken twice daily.
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Aspirin Placebo
Description: non-enteric-coated tablet taken twice daily.
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine
Description: 0.5 mg tablet taken once daily
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Colchicine
Description: 0.5 mg tablet taken once daily
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine Placebo
Description: tablet taken once daily.
Study NCT05633810 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Colchicine Placebo
Description: tablet taken once daily.
Study NCT05483153 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Infant-Directed Singing Coaching
Description: At-risk mothers will receive four, 30-minute, in-person infant-directed singing coaching intervention sessions that take place over two weeks. Mothers will learn how to better read infant cues and respond with sensitive singing. Infants will gain experience in self-regulation of arousal states.
Study NCT05000515 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High-resistance inspiratory muscle strength training
Description: Participants will perform inspiratory muscle strength training.
Study NCT05000515 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercise
Description: Participants will perform brisk walking.
Study NCT06156865 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention to address late talking
Description: this intervention is designed to support both speech and language development in children who are toddlers. Given the age group of children their parents are part of the intervention program. Importantly the frequency of the intervention can range from once to twice per week, with timing also designed to complement the particular agency
Study NCT05325320 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SMI/SIA Stigma Reduction Intervention
Description: Online course designed to reduce stigma behaviors towards serious mental illness and suicide ideation and attempt among medical students. It aims to improve medical students' healthcare delivery skills.
Study NCT05325320 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Disaster Preparedness Course
Description: Online course designed to improve professionals' skills and competencies for engaging in disaster preparedness.
Study NCT05097586 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active tDCS
Description: 2mA of direct current delivered in 15 sessions lasting 30 minutes each over 3 weeks
Study NCT05097586 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: workbook
Description: Self-directed depression in pregnancy workbook completed during each session to control the in-session brain state
Study NCT05097586 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: workbook
Description: Self-directed depression in pregnancy workbook completed during each session to control the in-session brain state