AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06347250 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: routine therapy
Description: All the participants are provided with the comprehensive rehabilitation (routine rehabilitation and swallowing function training). The routine rehabilitation included intervention for risk factors (blood pressure, blood lipids, blood glucose, smoking and alcohol restriction, exercise, etc.).~Regrading swallowing function training, both groups are given swallowing function training, including 1) exercises of closure of the vocal folds, pharyngeal, and laryngeal muscles exercises, and respiratory muscle strength training, for 15 min each time and twice per day. 2) isotonic／isometric swallowing exercises, supraglottic swallowing exercises, for 20 min each time and twice per day. 3) effortful swallowing exercises, and cough reflex training, for 10 min each time and twice per day.
Study NCT06347250 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: placebo block
Description: the patients were provided with normal saline. The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.
Study NCT06455397 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Building Emotional Awareness and Mental Health (BEAM) Program
Description: The BEAM Program builds on mHealth best practices and evidence-based program design principles with the core objectives of improving maternal mental health and fostering supportive parenting. Program content draws on transdiagnostic emotion-focused mental health and third wave Cognitive Behavioural Therapy principles such as Dialectical Behavioural Therapy, Acceptance and Commitment Therapy, and the Unified Protocol.~Program delivery will be facilitated through a mobile application. The BEAM program uses a stepped care model to address the pressing need for accessible and effective mental health interventions. Stepped care is a framework that provides mental health services in a tiered manner, ensuring that participants receive appropriate levels of support based on the severity of needs. At the heart of this model are BEAM peer coaches, who will have the most direct contact with participants. Peer coaches are trained to escalate concerns to the program clinical team as required.
Study NCT06362434 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Audiovisual stimulation
Description: The MOT IVR audiovisual stimulation task involves the 3D multiple-object-tracking paradigm composed of 6-8 high-contrast spheres which features are adapted to the visual ability of individuals with low-vision (luminosity = 80 nits, size = 1° to 3° visual angle). The spheres move for 20s. following random linear paths, bouncing on one another and on the walls of a virtual 3D cube when collisions occur. The participant, comfortably seated, is asked to track the moving cued target among moving distractors for 20s. A spatial sound is correlated to the movement of the cued target. After 20s., the movement stops and the participant is asked to select, using a laser pointer, the cued sphere among the distractors (mark-all procedure). Speed of the spheres is regulated by a staircase 1:1 procedure. The stimulation can here be stopped by the participant if required. After 3 blocks of 15x20s., the system stops and goes on stand-by mode until the next session. Data are collected in real time.
Study NCT05202418 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biofeedback Enhanced Treatment
Description: The intervention involves biofeedback enhanced cognitive behaviorally based coping skills treatment. Treatment will consist of a 6-visit group intervention conducted online, via Emory zoom. Groups will include 5-8 patients each. Sessions will include brief, daily homework to facilitate mastery that is developmentally tailored to youth (e.g., practice skills with support from phone or tablet apps). Groups will meet approximately every week for 6 weeks. Advanced Ph.D. students in clinical psychology and Principal Investigator will deliver the treatment protocol. Participants will complete questionnaires before and after each session to measure autonomic reactivity, lifetime stress, depression, anxiety in response to stress induction, and coping strategies.
Study NCT04518254 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood collection
Description: A blood sample will be collected before and after treatment administration
Study NCT04518254 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-Tyrosine 500 Mg
Description: The participants will be administered 4 capsules of L-Tyrosine 500 mg per oral route
Study NCT04518254 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: The participants will be administered 4 capsules of Lactose 500 mg (placebo) per oral route
Study NCT04518254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive tasks
Description: The participants will perform cognitive decision-making tasks: Simon task and masking task after treatment administration
Study NCT04518254 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stress exposure
Description: Unpleasant but not painful skin stimulations will be administered to the participants at variable intervals on the left leg during the cognitive tasks
Study NCT04518254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Anxiety scale
Description: Spielberger's State Trait Anxiety Inventory (STAI) will be filled by the participants before and after cognitive tasks
Study NCT05458661 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Clinical Prototype BioBase (SN 07 and SN 08)
Description: Scheimpflug- or OCT based corneal tomographers with the ability to measure anterior and posterior corneal curvature maps >6mm diameter and corneal pachymetry maps >6mm.
Study NCT06141837 — intervention group
Intervention type: OTHER
Intervention: Observation
Description: No intervention: observational study
Study NCT04518254 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electromyography (EMG)
Description: Electromyography measurements will be performed during cognitive tasks.
Study NCT04867694 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BCC
Description: Behavior change communication on Nutrition, Health \& Hygiene, including (but not limited to) awareness of dietary diversification from 6 months of age and adequate complementary feeding; and raising awareness of good water and hygiene practices.
Study NCT04867694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Preventive supplement
Description: Monthly delivery of a nutritional supplement: enriched flour (CSB++), at a dose of 3 kg/month/beneficiary child. The nutritional supplement is limited to \[6-11\] months old children diagnosed as non-wasted (green MUAC); or children \[12-59\] months old for 6 months after discharge from a CMAM treatment or consolidation program.
Study NCT04867694 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: MNP
Description: Delivery of micronutrient powders to \[12-23\] months old children (30 sachets per month for 2 months, every 6 months, according to international recommendations).
Study NCT04867694 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Water purification input
Description: Monthly delivery of a water purification input: bleach or flocculant/decontamination sachets for the potabilization of the water of the whole household. The water treatment input is limited to households with \[6-11\] months old children, or children \[12-59\] months old enrolled in a CMAM treatment program and for 6 months after discharge.
Study NCT04867694 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family MUAC
Description: One-time delivery of a mid-upper arm circumference (MUAC) measuring tape and training of families in its use, and actions to be taken based on the results. This will involve distributing Shakir bands to all households with \[6-59\] months old children and training mothers/guardians, or any other family members who express an interest, in screening for wasting using the MUAC criteria, and explaining the procedure to follow if the child tests positive in the family.~Formative supervision of MUAC measurement in families. The training will be carried out by the members of the care groups and at each home visit, they will be able to ensure that the MUAC measurement technique is well mastered by the mother (or another member) and correct the technique if necessary.
Study NCT04867694 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Screening by care group
Description: Monthly screening by the care group volunteers of the children they follow, using the MUAC.~Referral to the health center of \[6-59\] months old children screened as malnourished (result of MUAC orange or red), and follow-up on referral to confirm child was enrolled
Study NCT04867694 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CMAM compliance
Description: Weekly follow-up of \[6-59\] months old children under treatment and for 6 months after discharge from the national treatment and consolidation program : care group volunteers follow children under treatment until they recover and for the whole duration of their consolidation (for children cured of severe emaciation) through weekly home visits.~They monitor treatment adherence (i.e., families follow the planned schedule of visits and receive inputs for treatment or consolidation) and treatment compliance (i.e., the malnourished or consolidating child receives the planned dose of therapeutic or supplementary food each day).
Study NCT05577949 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Structured aerobics exercise
Description: A 12 week structured aerobics exercise program will be offered. The patient has to perform exercise five times a week , 30 minutes a day
Study NCT04518254 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electroencephalography (EEG)
Description: Electroencephalography measurements will be performed during cognitive tasks.
Study NCT05047575 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: REASSURE
Description: REASSURE utilizes remote patient-reported outcomes assessments to comprehensively assess symptoms, promotes practice change by providing feedback reports to oncologists and engaging primary care providers (PCPs) in survivorship care, and reduces the burden of follow-up by substituting an oncology visit for thriving survivors with reassurance messaging and encouragement to pursue preventive care.
Study NCT05589883 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: EMPOWER-Latinx
Description: EMPOWER-Latinx will be delivered in Spanish by videoconferencing (i.e., Zoom, WebEx) with a trained study interventionist. Intervention modules will be audio- and video-recorded (videorecording optional).
Study NCT05524610 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sexual Function Screening Approach
Description: The screening approach will consist of:~1. Standardized use of the PROMIS SexFS Brief in a clinic setting. This tool assesses sexual interest/desire, arousal, discomfort/pain, climax, and satisfaction, among other SD concerns and has comparable sex-specific versions. It has been validated in adult cancer populations.~2. An implementation package to aid in successful implementation. The implementation package will be finalized in the non-trial portion of this study, which will include iterative intervention adaptation. The protocol will be amended as needed to include any relevant updates to the screening approach. Some components may vary per site.
Study NCT05135637 — intervention group
Intervention type: OTHER
Intervention: Mobile health services
Description: Mobile health services (MHS) will be deployed with one team per UC. MHS will focus on underserved areas to provide basic health services, immunization, \& health and nutrition counseling for under-five children \& WRAs.
Study NCT05135637 — intervention group
Intervention type: OTHER
Intervention: Private practitioner engagement for immunization
Description: Private healthcare providers (HCPs) will be taken on board to increase coverage of immunization. HCPs will offer routine vaccination to all under-five children visiting their clinics. Project team will liaison with EPI to arrange vaccines for them.
Study NCT05135637 — intervention group
Intervention type: OTHER
Intervention: Community engagement and mobilization
Description: Community engagement \& mobilization will focus on immunization, breastfeeding practices, \& optimal care-seeking for both pregnant women and young children. Opinion leaders will be engaged to gain support for activities.
Study NCT05135637 — intervention group
Intervention type: OTHER
Intervention: Sehat Nishani - a health, nutrition and immunization app
Description: Sehat Nishani App will be launched to assess feasibility of a health, \& immunization app to capture information on birth, nutrition, immunization \& growth records. Lady health workers (LHWs), lady health visitors (LHVs) in government health facilities, EPI vaccinators \& HCPs will be engaged to use app.
Study NCT06247462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ibuprofen 600 mg
Description: 600 mg of ibuprofen was ingested 12- and 1-hours prior to exercise.
Study NCT06247462 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Corn Starch
Description: 600 mg of corn starch (placebo) was ingested 12- and 1-hours prior to exercise.
Study NCT06547866 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: zanubrutinib + BGB-11417
Description: The investigational medicinal products (IMP) are Zanubrutinib (BGB- 3111) and BGB-11417.Treatment will be administered for a total of twenty 28 day cycles:~Cycle 1 with zanubrutinib only~Cycle 2 with zanubrutinib plus BGB-11417 ramp-up cycle 2, day 1 : 10mg cycle 2, day 2 : 20 mg cycle 2, day 3 : 40mg cycle 2, day 4-7 : 80md daily cycle 2, day 8 and beyond : 160 mg daily~Cycles 3-20 with zanubrutinib plus BGB-11417 full dose
Study NCT04566315 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Arteriography knee arteriography
Description: arteriography and an injection of inert microparticles of 75 μm in neovessels
Study NCT05173649 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Calisthenic Training
Description: Calisthenic Training Performed thrice a week after baseline assessment Standard Physical therapy treatment along with following exercises.~1. Abductor-Adductor leg raise~2. Alternate toe touch~3. Knee Bend~4. Prone leg extension~5. Forward Lunges~6. Toe Raise/ Calf raise Progressive training include following exercises.~1. Leg Lifts 2. Jack Twists 3. Side Lunges 4. Short bridge 5. Calf Raise with weight.
Study NCT05173649 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Neuromuscular Training
Description: Neuromuscular Training Performed thrice a week after baseline assessment Standard Physical therapy treatment along with following exercises.~1. Up and down step exercise in posterior and lateral directions.~2. Walking in anterior and posterior~3. Directions with eyes opened and eyes closed.~4. Walking in lateral direction with eyes opened and eyes closed.~5. Standing on one extremity~6. Inclination in anterior and lateral direction with eyes opened and closed. Progressive training includes following exercises.~1. Up and down on Bosu exercise. 2. Plantar flexion on minitrampoline. 3. Standing on one extremity on Bosu. 4. Standing on one extremity on minitrampoline
Study NCT05980533 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ultrasound
Description: Ultrasound at hospital discharge and at follow up at 7-10 days
Study NCT04949165 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Iron Supplementation
Description: low dose ferrous sulphate (65mg elemental iron) supplements
Study NCT06064890 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrathalamic AAV.PGRN administration
Description: One-time MRI-guided stereotaxic infusion of AAV.PGRN into the brain
Study NCT06064890 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Intrathalamic AVB-101
Description: AVB-101 is made from an adeno-associated virus, serotype 9 (AAV9). AAVs are small viruses that are naturally occurring and do not cause illness or infection on their own. AVB-101 has been modified to contain a copy of the correct (non-mutated) GRN gene, plus some other genetic material to enable the GRN gene to function inside neurons (cells within the brain). AVB-101 has also been modified so that it cannot divide and make new copies of itself (known as 'replication'), which means that it cannot cause disease or a large immune response in your body.
Study NCT06214650 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Radiofrequency
Description: Experimental group will receive the common exercise program associated with a radiofrequency treatment using INDIBA® (INDIBA Activ 7, Barcelona, INDIBA S.A.) at a frequency of 448 hertz. It will use the capacitive electrode as a method of preparation and vascularization of the superficial tissues and immediately, within the same session, the resistive electrode to stimulate deep tissues. This treatment is based on the protocols established by INDIBA® S.A.~It will consist of one weekly diathermy session of thirty minutes during ten weeks. The use of diathermy will not be interrupted throughout the session.~The common exercise program consist in a ten abdominal exercises (including recti abdominis, transversus and obliques). It will practised at home only just three days at week.
Study NCT06214650 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Control group will receive a weekly INDIBA® session in the abdominal area with the same protocol as the experimental group in athermic mode (placebo treatment) and the common exercise program. The session will last thirty minutes and will be carried out by the research physiotherapist during ten weeks.
Study NCT04796649 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: B-Cure laser pro
Description: The B-Cure laser Pro is a portal, non-invasive, low level laser therapy device, that emits light in the near infrared (808nm) over an area of 1X4.5 cm2 with power output of 250mW, and energy dose of 5J/min.
Study NCT04796649 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Sham
Description: The sham device is externally identical to the B-Cure Pro and emit the same guiding light, but does not emit the therapeutic near infrared rays.
Study NCT06335979 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PIT565
Description: In each cohort, there will be 3 sentinel participants. Additional participants might be added depending on safety and observed biological activity.
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EEG recording 1
Description: Multichannel EEG recording in eyes opened and eyes closed relaxed state and during imagined movement (all one experimental session). EEG device usbamp (company Guger Technologies, Austria) will be used.
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EEG recording 2
Description: Multichannel EEG recording in eyes opened and eyes closed relaxed state and during imagined movement (all one experimental session). This intervention will take place six month after EEG recording 1. EEG device usbamp (company Guger Technologies, Austria) will be used.
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Sensory Test
Description: Test for mechanical sensations of the feet and shins of both legs as well as on the trapezoidal muscle on both sides. Semmes-Weinstein Monofilaments will be used
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Brief Pain Inventory 1
Description: This questionnaire that ask about any acute or chronic pain
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Multidimensional health locus of control
Description: Questionnaire that test personal belief about control of one's own health
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Sensory test thermal
Description: Test of thermal sensations (thermal roller) of the feet and shins of both legs as well as on the trapezoidal muscle on both sides. A Somedic SenseLab Rolltemp device will be used
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Neuropathic pain symptoms
Description: Questionnaire that test for neuropathic pain symptoms
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: McGill pain questionnaire
Description: Questionnaire assess three separate components of experiencing pain; the sensory intensity, the emotional impact and the cognitive evaluation of pain.
Study NCT04665492 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pain Catastrophising Scale
Description: Questionnaire use to identify individual pain experience.
Study NCT05079100 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: postpartum contraception method counselling
Description: It will be face-to-face counseling with females about the use of postpartum contraception methods within 6 weeks postpartum.
Study NCT04401982 — intervention group
Intervention type: DRUG
Intervention: Netarsudil ophthalmic solution 0.02% one drop nightly for 1-2 weeks
Description: Netarsudil ophthalmic solution 0.02% one drop nightly for 1-2 weeks will be administered
Study NCT05487092 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Description: Letrozole 2.5mg daily for 6 months
Study NCT05487092 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05241522 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Tc-99m-Tilmanocept
Description: Administration of 3 different doses of Tc-99m-Tilmanocept prior to SPECT-CT imaging of the kidney in order to determine the safety and efficacy of tilmanocept imaging for differentiating diabetic kidney disease from other causes of kidney disease.
Study NCT04571580 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal Saline
Description: intracoronary infusion with normal saline
Study NCT04571580 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Reteplase Injection 9mg
Description: low-dose intracoronary fibrinolytic therapy with reteplase 9mg