AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04843072 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Evolut R/PRO bioprosthesis
Description: To compare Evolut R/PRO versus Sapien S3/Ultra in failing surgical bioprostheses
Study NCT04843072 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Edwards Sapien S3/Ultra bioprosthesis
Description: Edwards Sapien S3/Ultra bioprosthesis
Study NCT06213935 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norepinephrine
Description: after spinal anesthesia, norepinephrine will be injected intravenous as bolus at 0.05 μg/kg, followed by norepinephrine infusion at a rate of 0.05 μg/kg.min to prevent post spinal hypotension
Study NCT06213935 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midodrine
Description: 10 mg tablets of midodrine 1 hour before spinal anesthesia to prevent post spinal anesthesia hypotension
Study NCT05682898 — intervention group
Intervention type: PROCEDURE
Intervention: Timing of colorectal cancer surgery
Description: The timing of colorectal cancer surgery is different according patients' different conditions which is difined as more than 7 weeks or less than 7 weeks.
Study NCT04545411 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dapagliflozin 10 MG [Farxiga]
Description: 4-Week, double-blind, once daily oral 10mg dapagliflozin
Study NCT04545411 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dapagliflozin 10 MG [Farxiga]
Description: 4-Week, double-blind, once daily oral 10mg dapagliflozin
Study NCT04545411 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: REMD-477
Description: 4-Week, double-blind, once weekly subcutaneous injection with 35mg REMD-477 in 1mL solution.
Study NCT04545411 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 4-Week, double-blind, once weekly subcutaneous injection with placebo in 1mL solution.
Study NCT06507098 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Video-assisted training
Description: Patients received a QR code and a link for access to a YouTube video recorded to this effect where the process of setting up the respiratory polygraph was explained. The contents of the video were the same as those in the face-to-face instructions. The visualization of the video was at home, and it could be viewed as many times as necessary.
Study NCT06507098 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Nurse training
Description: A trained nurse with long experience in home sleep studies explained the setup of the respiratory polygraph. At the end of the intervention doubts about the procedure were addressed. Patients did not have access to the video.
Study NCT06225804 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABSK112
Description: In the escalation part, patients will receive a single dose of oral ABSK112 on Cycle1 Day1 only, and then patients will continuously receive ABSK112 once daily (QD) or twice daily (BID) in subsequent cycles. In the expansion part, patients will each be treated at the selected RDE dose level.
Study NCT05402904 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: nerve conduction study
Description: Routine nerve conduction study on both lower limbs as well as F- wave , Hoffman reflex and somatosensory evoked potential.
Study NCT05892536 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: dental regenerative endodontics
Description: regenerative procedures performed in necrotic mature permanent teeth
Study NCT05892536 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: dental regenerative endodontics
Description: regenerative procedures performed in necrotic mature permanent teeth
Study NCT06166290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CO2 LASER Vaporisation
Description: The CO2 LASER vaporization procedure is described as follows. Patient positioning will be done, and patient will be anesthetized. Local infiltration with 2% lidocaine, nerve block or general anesthesia will be given. The surgical field will be disinfected and draped. The perianal and anal area will be investigated for lesion. CO2 LASER from 20 cm distance in a continuous wave mode and 20 W power will be applied. After warts melts, necrotic tissue will be removed. After the operation was completed, residual debris will be wiped away with a piece of moist gauze. Bacitracin cream applied over the treated areas. Upon discharge acetaminophen 1-gram q8 and Ibuprofen 600 q8 for pain.
Study NCT06166290 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Electrosurgical Fulguration
Description: The procedure is described as follows. Patient will be administered regional or general anesthesia, placed in prone jack-knife position. Prepping and draping will be done. The perianal and anal area will be investigated for lesion. The lesions will be excised, and the bases will be fulgurated. Electrosurgery device will be used in monopolar setting (30 Cut mode, 30 Coag mode). After procedure local analgesics total MERCAINE/EPI 0.25% 20 ml on both sides of the lesion. Bacitracin cream applied over the treated areas. Upon discharge 1000 mg of Tylenol every 8 hours along with 600 mg of ibuprofen every 8 hours.
Study NCT05580185 — intervention group
Intervention type: DEVICE
Intervention: RESPINOR DXT
Description: Blinded, continuous diaphragmatic excursion measurements by DXT will be conducted during the patients' first SBT. The recording shall be initiated 15 minutes prior to the first SBT and will end 15 minutes post SBT.
Study NCT05303337 — intervention group
Intervention type: OTHER
Intervention: Stool sampling
Description: Stool samples will be collected from participants at baseline and W52
Study NCT06198218 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Scapular mobilization
Description: Group A: will be treated with manual scapular mobilization in upward rotation and downward rotation, adduction and abduction of scapula.Sets of 10 repetitions were applied with a rest interval of 30 seconds between set for 20 minutes, activity based scapular mobilization(Codman pendulum exercises, scapular pushups, band wall apart ,wall ball circles and advance study wall pushups) along with conventional physical therapy program(heating,EMS,stretching for tight muscles , strengthening exercises and graduated active exercises) for 25 min
Study NCT06198218 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical therapy program
Description: Group B:will receive conventional physical therapy program including (heating to improve circulation and release muscle tension,EMS,stretching for stiff muscle,weight bearing, strengthening exercises \& graduated active exercises)for 20 min along with activity based scapular mobilization (Codman pendulum exercises,band wall apart,wall ball circles, scapular pushups and advance study wall pushups)for 20 min with 5 min resting interval.
Study NCT05528328 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CACIPLIQ20®
Description: CACIPLIQ20®
Study NCT05528328 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (saline solution)
Description: Placebo (saline solution) administered in identic al vials
Study NCT05303337 — intervention group
Intervention type: OTHER
Intervention: Blood plasma collection
Description: Blood plasma collection to assess persistent inflammation, immune activation and HIV reservoir at baseline,W24,W52
Study NCT06293001 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT06321783 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Assessment
Description: Evaluation of cervical proprioception, hand-eye coordination, postural control and endurance of cervical muscles
Study NCT06504823 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Light level
Description: light application
Study NCT06504823 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Light level
Description: light application
Study NCT04971408 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: passive heat stress
Description: as above
Study NCT04971408 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: control
Description: participant engage in activity as usual
Study NCT05533658 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: VisionPure Dietary Supplement
Description: Subjects will consume two softgels capsules of the Treatment (VisionPure) once daily for 60 days. At Day 0, they will come in for a Comprehensive Eye Exam, a National Eye Institute Visual Functioning Questionnaire, and a series of Cognitive Function Exams. After 60 days, subjects will return and repeat the same questionnaires and exams from Day 0.
Study NCT05298631 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Stabilization exercises
Description: The activation of deep cervical muscle to reduce the activity of surface muscles is known as stabilization exercises
Study NCT05298631 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic exercises
Description: The exercises in which muscle tension remains constant but muscle length changes is known as dynamic exercises
Study NCT05329610 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Beta-alanine
Description: Slow-release beta-alanine.
Study NCT05329610 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Taste and appearance-matched placebo (tapioca starch).
Study NCT06461364 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Assessment of cuspal deflection of bulk-fill restorations
Description: To assess the performance of bulk-fill restorations on premolar teeth in class II cavities using some selected FDI criteria, a total sample size of 30 (10 for each group test) will be sufficient to detect: an effect size of 1.22 at a power (1-β error) of 0.8 and using a two-sided hypothesis test and a significance level (α error) 0.05 for data. Two teeth will be added to each group to compensate drop out samples.
Study NCT05533658 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will orally consume two softgel capsules of Placebo once daily for 60 days. At Day 0, they will come in for a Comprehensive Eye Exam, a National Eye Institute Visual Functioning Questionnaire, and a series of Cognitive Function Exams. After 60 days, subjects will return and repeat the same questionnaires and exams from Day 0.
Study NCT06385561 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tramadol
Description: Tramadol is administered orally twice daily in a dosage of 100 mg (daily total of 200 mg)
Study NCT06385561 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is administered orally twice daily.
Study NCT05620173 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Vedea Amblyopia Therapy (VAT)
Description: Children will use the VAT for 5 days per week, 30 minutes per day. They play VR-games using a VR-headset, which content is optimized for dichoptic training.
Study NCT05620173 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vedea Amblyopia Therapy (VAT)
Description: Children will use the VAT for 5 days per week, 30 minutes per day. They play VR-games using a VR-headset, which content is optimized for dichoptic training.
Study NCT05620173 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Occlusion therapy
Description: Children are given an eye patch to occlude their dominant eye with for a prescribed number of hours per day. This may typically range anywhere between 2-8 hours per day, depending on the severity of the amblyopia.
Study NCT06131567 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Implantoplasty
Description: Implantoplasty as surface decontamination method
Study NCT06131567 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Implantoplasty
Description: Implantoplasty as surface decontamination method
Study NCT05484648 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Dexamethasone has been used to generally favorable results in peripheral nerve blocks as adjunct. Several studies have reported prolongation in the duration of ropivacaine, mepivacaine and bupivacaine when used in combination with dexamethasone.~Various mechanisms for the beneficial adjunctive effect of dexamethasone with Local Anesthetics (LA) have been proposed. One theory suggests that the improved analgesia and increased blockade duration is due to its anti-inflammatory properties. It also acts as a local vasoconstrictor and thus may act by reducing LA absorption. Furthermore, it also increases the activity of inhibitory potassium channels on nociceptive C-Fibers.
Study NCT05484648 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine is another promising drug being used as a local anaesthetic adjuvant in peripheral nerve blocks. It is an alpha-2 agonist, which has shown to have prolonged duration of postoperative analgesia when given with LA for peripheral nerve blocks with other beneficial effects such as reducing the opioid consumption. Alpha-2-agonists such as dexmedetomidine cause hyperpolarization-activated cation currents which inhibit the transmission of nociceptive fibers.
Study NCT04699786 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Arm A , Arm B, Arm C, & Arm D
Description: All arms will receive the same intervention, but at different time points. All arms will be offered the option to learn their research results in personalized five-year risk estimate of getting Alzheimer disease dementia. Arms A \& C participants will receive their risk estimate about two weeks after consent is signed and Arms B\& D will receive their risk estimate about one year after consent is signed. The risk estimate returned to participants is based on research results from individual genotyping results, imaging or plasma amyloid testing \& demographic characteristics. All arms will complete psychosocial and cognitive testing. Also, surveys used in this study will ask about participants' experiences and feelings after learning their risk estimate. All arms will receive follow up calls at one week post disclosure of the risk estimate and surveys two, six, and twelve months post disclosure. Arms A \& C will have extra surveys at twenty-four months post disclosure.
Study NCT05493644 — intervention group
Intervention type: OTHER
Intervention: Remedial treatment within 3 months
Description: Remedial therapy was performed within 3 months
Study NCT05493644 — intervention group
Intervention type: OTHER
Intervention: Remedial treatment within 3 to 6 months
Description: Remedial therapy was performed within 3 to 6 months
Study NCT05493644 — intervention group
Intervention type: OTHER
Intervention: Remedial treatment within 6 to 12 months
Description: Remedial therapy was performed within 6 to 12 months
Study NCT05493644 — intervention group
Intervention type: OTHER
Intervention: Remedial treatment after 12 months
Description: Remedial therapy was performed after 12 months
Study NCT04739137 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: DDiVAT Testing
Description: Participants will self examine his/her distance visual acuity via application in a simulation room of our department with certain predetermined environmental lighting conditions using the same smart devices.
Study NCT04739137 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Distance visual acuity assessment via ETDRS chart
Description: The distance visual acuity of each participant will be measured with the conventional method via ETDRS chart
Study NCT06108024 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: SM-020 gel 1.0%
Description: SM-020 gel 1.0% will be applied topically. Subjects will be treated with twice daily application to 5 to 10 SKTLs for approximately 28 days.
Study NCT06108024 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle gel
Description: Vehicle gel will be applied topically. Subjects will be treated with twice daily application to 5 to 10 SKTLs for approximately 28 days.
Study NCT05057936 — intervention group
Intervention type: BIOLOGICAL
Intervention: COVID vaccine
Description: The enrolled patients will received COVID-19 vaccine according to the vaccine protocol in Thailand ie The ChAdox-1 nCOV-19 vaccine (day 1, day 84, 12 weeks duration) or Corona vac 2 doses (day 2, day 21, 3 weeks duration) of the study. All the participants underwent blood drawn for antibody and cellular immunity measurement before the final dose of vaccination, with 7 days before first vaccine dose and eight weeks after the second doses
Study NCT04521582 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine
Description: The facility-based community health worker will receive protocol-driven training to initiate amlodipine for hypertensive patients. These patients will receive lifestyle counseling by Female Community Health Volunteer through home visits (5 times \[including baseline and end of the study\] in the active municipality and 3 times \[including baseline and end of the study\] in the control municipality).
Study NCT04521582 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle counselling
Description: Female Community Health Volunteer will provide lifestyle counseling at the participant's home
Study NCT05388331 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT05628532 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Use of the DBLG1 system
Description: During the treatment period, the patient will use the DBLG1 system (consisting of a DBLG1 handset with an embedded software named loop mode, a TERUMO MEDISAFE WITH patch pump and a Dexcom continuous glucose monitoring (CGM) G6). The main function of DBLG1 System is to adjust the insulin delivery at the correct time in order to maintain the patient's blood glucose in the target range and thus minimize both hypoglycaemic events and long-term complications associated with elevated average glycemia.
Study NCT05923437 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Feeding model group with a chronobiological approach
Description: Breast milk will be given to the newborns in the intervention group for 3 days in line with the feeding model with a chronobiologic approach simultaneously with the provision from the mother, and the newborn will be ensured to receive breast milk in accordance with the day cycle. Within the scope of the study, firstly, mothers and nurses in the NICU will be informed about the study. Mothers will be asked to put the milk mothers express between 06:00-17:59 in the daytime breast milk storage bag and the milk mothers express between 18:00-05:59 in the nighttime breast milk storage bag and bring them to the unit. The brought breast milk will be prepared by the nurses by matching day and night milk according to the dates, with the first milk brought in priority, and the newborns will be fed by using the time of day factor (cycle so that the milk collected during the day will be given during the day and the milk expressed at night will be given at night).
Study NCT04521582 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle counselling
Description: Female Community Health Volunteer will provide lifestyle counseling at the participant's home
Study NCT04972695 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Fundus Photographs (retinographies)
Description: Fundus photographs under mydriasis
Study NCT06266169 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: making artificial intelligence based decisions of gamete, embryo and endometrial potential
Description: The method of Raman spectroscopy is based on the registration of inelastic scattering of photons. Each compound has its own spectral pattern when using a certain type of monochromatic radiation (laser). With this method, it is possible to obtain metabolic fingerprints from the objects being studied. Luminescent spectroscopy is a type of spectroscopy used to register emission from objects that occurred after absorbing the exciting (primary) radiation. Spectrophotometry is the detection of radiation in the visible area of the spectrum. Raman spectroscopy is used for the spent medium and semen to build artificial intelligence model and make prognosis of function for each object. For endometrium, luminescent spectroscopy and spectrophotometry are used to build the model and test its clinical relevance
Study NCT04614064 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London Underground ambient particulate matter
Description: Exposure to particulate matter on the London Underground
Study NCT04614064 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exposure to London air ambient particulate matter
Description: Exposure to ambient particulate matter on the London Overground (as a proxy as a proxy for a clean air London area while maintaining other aspects of a train journey)
Study NCT06282107 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: BiSAAE
Description: SAAE is a catheter-based percutaneous transluminal procedure which selectively injects ethanol into bilateral adrenal artery to ablate part of the adrenal gland for suppression of excessive aldosterone and catecholamines
Study NCT06282107 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: traditional triple antihypertensive treatment
Description: traditional triple antihypertensive treatment
Study NCT05862415 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: therapeutic Exercise
Description: The circular training method was used in the resistance training phase. During the aerobic training phase, a series of movements from moderate intensity to vigorous intensity was performed. The step loading periodization principle was taken into account in both resistance training and aerobic exercises.~The RT lasted approximately 20-25 min per session and included two sets of 8-20 repetitions, with a rest interval of 1-2 min. The RT exercises included: squat, barbell bent-over row, overhead press, plank, lateral pull down, triceps push down, barbell curl, leg extension, leg curl, lunge, barbell bench press, crunches etc.~For the aerobic training: Intensity was established between 50-65% and 80-85% of HRmax for both groups (SAG and ASG). Aerobic training includes walking and running periods and was carried out on a 400 m outdoor track. In periodization, especially 1st-4th.