AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06734273 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sleeve Gastrectomy
Description: Subjects in both the interventional group (n=21) and the control group (n=21) will undergo sleeve gastrectomy.
Study NCT06734273 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sleeve Gastrectomy
Description: Subjects in both the interventional group (n=21) and the control group (n=21) will undergo sleeve gastrectomy.
Study NCT06735157 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Repetitive transcranial magnetic stimulation
Description: Repetitive transcranial magnetic stimulation (intermittent theta burst stimulation) will be delivered using a Magstim Rapid 2 stimulator (Magstim, Whitland, UK) guided using neuronavigation (Brainsight, Rogue Research, Montreal, QC, Canada) to target primary motor cortex. Participants will receive 14 days of stimulation over a 3-week period. Stimulation will use a protocol called accelerated iTBS (Duprat et al., 2016) whereby iTBS will be delivered three times during the same study session. Each iTBS session will deliver 600 pulses in 50 Hz bursts of 3 pulses for a total of 1800 pulses delivered each day. iTBS sessions will each be separated by 15 minutes (Duprat et al., 2016; Wu et al., 2013). Stimulation will be delivered at 70% of the participant's resting motor threshold. Immediately following each 600-pulse period of iTBS, individuals will participate in 5 to 10 minutes of AR vestibular rehabilitation therapy.
Study NCT06735157 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Augmented reality vestibular rehabilitation therapy
Description: Participants will complete the vestibular training through Nreal Air AR Glasses (Nreal, China). The vestibular training task was custom-made in Unity V2021.3.14fI software using C+ script language. Participants will be standing upright for the AR training, with a safety bar positioned directly in front of them should they need to hold onto something. A large cross-shaped target will be positioned approximately 3 feet in front of the participant's head with its vertical center aligned with the participant's midline. This will act as a visual starting point. The training is adapted from clinical vestibular rehabilitation training methods used in PCD. The vestibular training task consists of locating and tracking a series of moving 3-dimensional balls presented at random within the participant's field of view.
Study NCT06735157 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Augmented reality vestibular rehabilitation therapy
Description: Participants will complete the vestibular training through Nreal Air AR Glasses (Nreal, China). The vestibular training task was custom-made in Unity V2021.3.14fI software using C+ script language. Participants will be standing upright for the AR training, with a safety bar positioned directly in front of them should they need to hold onto something. A large cross-shaped target will be positioned approximately 3 feet in front of the participant's head with its vertical center aligned with the participant's midline. This will act as a visual starting point. The training is adapted from clinical vestibular rehabilitation training methods used in PCD. The vestibular training task consists of locating and tracking a series of moving 3-dimensional balls presented at random within the participant's field of view.
Study NCT06735157 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: SHAM repetitive transcranial magnetic stimulation
Description: Sham repetitive transcranial magnetic stimulation will be delivered using a Magstim Rapid 2 sham stimulator (Magstim, Whitland, UK) guided using neuronavigation (Brainsight, Rogue Research, Montreal, QC, Canada) to target primary motor cortex. Participants will receive 14 days of sham stimulation over a 3-week period. Stimulation will use a protocol called accelerated iTBS (Duprat et al., 2016) whereby sham iTBS will be delivered three times during the same study session. Each sham iTBS session will sound and feel identical to real iTBS delivery, but will not deliver a stimulating current. Sham iTBS sessions will each be separated by 15 minutes (Duprat et al., 2016; Wu et al., 2013). Sham stimulation will be delivered at 70% of the participant's resting motor threshold. Immediately following each 600-pulse period of sham iTBS, individuals will participate in 5 to 10 minutes of AR vestibular rehabilitation therapy.
Study NCT06735105 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Scanning parameter
Description: Based on abdominal scanning, TSE-DWI,ZOOMIT DWI and EPI-DWI scans were performed, and the study was divided into two steps according to the nanomotion criteria. The first step was self-controlled, which was divided into experimental group and control group. The experimental group included TSE-DWI,ZOOMit DWI, and the control group included EPI-DWI. Then the image quality was evaluated by subjective and objective evaluation indexes. In the second step, the three DWI stages were performed separately by four diagnosticians, with an interval of 1 month, and statistical analysis was performed at the end.
Study NCT06734546 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise intervention
Description: The exercise intervention entails 6 months of supervised exercise on a hometrainer at high or moderate intensity, 3 times per week
Study NCT05168124 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Acceptance Commitment Therapy for chronic fatigue
Description: ACT was originally developed for the treatment of depression and anxiety. Recently, a single study investigated ACT as a therapeutic approach in CFS/ME and showed no negative effects on disease progression. ACT is characterized by acceptance- and mindfulness-based techniques, serves to promote acceptance and the development of new value goals, and can thereby open up new perspectives on life, which would be promising in terms of a reduction of symptom focus that seems to be a crucial effective factor for an improvement in exhaustion states. The intervention involves psychoeducation and teaching coping strategies for dealing with symptoms, most notably fatigue, postexertional malaise, unrestful sleep, cognitive decline, and orthostatic dysregulation. For this purpose, the therapy manual designed for anxiety disorders is adapted to the needs of patients with CFS, the exercises and worksheets that teach the acceptance- and mindfulness-based techniques are adapted to the symptoms.
Study NCT05168124 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Micro breaks in everyday life for chronic fatigue
Description: In terms of break design in the work context, research in recent years has increasingly focused on so-called micro breaks (MB) - mini breaks of one to five minutes in length. Transferred to mini breaks in everyday life (MBEL), there have been found fundamentally positive effects in terms of performance, vitality and well-being, which could also have a positive impact on the clinical picture of CFS/ME. However, practically no research results are yet available with regard to the implementation of MB in everyday life of patients with CFS/ME. The effects of MB, on the other hand, have been tested several times in everyday work settings and showed desirable effects on mood, attention, fatigue, vitality, performance, and well-being.
Study NCT05736159 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Method of assessment of school maturity
Description: Psychophysiological examination of the functional readiness of the child for admission to school.
Study NCT05736159 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Assessment of school adaptation
Description: Psychophysiological examination of the success of school education of first graders.
Study NCT06548750 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intrinsic and Ectrinsic Exercise
Description: Intrinsic and extrinsic muscle strengthening exercises
Study NCT06548750 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intrinsic Exercise
Description: Intrinsic muscle strengthening exercises
Study NCT05103943 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SPECT MPI
Description: SPECT MPI including dynamic acquisitions for stress, rest MBF and MFR
Study NCT04642599 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bimanual motor skill learning with the REAplan® rehabilitation robot
Description: REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Study NCT04642599 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bimanual motor skill learning with the REAplan® rehabilitation robot
Description: REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Study NCT06177028 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide 10 mg
Description: Lenalidomide is a cancer drug, It is also known by it's brand name Revlimid.
Study NCT06177028 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lenalidomide 10 mg
Description: Lenalidomide is a cancer drug, It is also known by it's brand name Revlimid.
Study NCT04678323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lifestyle Management
Description: Participants in this group will receive lifestyle management.
Study NCT04678323 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lifestyle Management
Description: Participants in this group will receive lifestyle management.
Study NCT04793269 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: no intervention
Study NCT06272292 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: EOS
Description: Every subject in this study will undergo a radiographic analysis of the hip and spine using a low-dose, full-body biplanar X-ray acquisition (in standing, sitting and squatting position, EOS imaging).
Study NCT06272292 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 3D motion lab analysis
Description: A hip-specific 3D motion analysis will be performed. The 3D motion protocol will be divided into 2 main sections.~First section: Consist of movements categorized within the activities of daily living (walking at self-selected speed, uphill walking, standardized deep squat and non-standardized deep squat)~Second section: Consists of movements that are categorized within athletic training and have been specifically chosen to induce large hip ranges of motion (Sumo squats, dead lifts, forward lunges, running uphill and downhill)~Each movements will be repeated 6 times. Three times with the dominant foot/opposite leg on the force plate to collect kinetic data. All data will be captured using two 10-15 camera 3D motion capture systems and one capturing an instrumented treadmill (M-gait)
Study NCT05597709 — intervention group
Intervention type: PROCEDURE
Intervention: Ultrasound attenuation parameter measurement, fasting blood glucose and fasting insulin determination
Description: Eligible participants will receive ultrasound attenuation parameter with iLivTouch, fasting blood glucose and fasting insulin determination
Study NCT04628468 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: moveUp
Description: Mobile application for use in the rehabilitation of primary knee and hip arthroplasty
Study NCT04628468 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Predefined number of traditional physiotherapy sessions
Description: exercises with a physiotherapist being physically present
Study NCT06465719 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Minimally invasive basal ganglion hematoma evacuation with Tract-based AI Robot Guiding System
Description: Basal ganglion hemorrhage patients will be operated on hematoma puncture and aspiration with Tract-based AI Robot Guiding System
Study NCT06465719 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Hemocoagulase Bothrops Atrox for Injection；Nicardipine
Description: Basal ganglion hemorrhage patients will be managed with guideline-based medications without surgery. Hemocoagulase Bothrops Atrox for Injection belongs to the drug class of Hemostatic Agents. Nicardipine is a calcium channel blocker (CCB) drug to control blood pressure.
Study NCT06259396 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: The 8x5 Diet
Description: A virtual, dietitian-counselled, healthy dietary pattern defined by its fat intake, its daily eating pattern, keeping adequately hydrated, having a variety of whole grains, fruit and vegetables, and use of certain plant fibres.
Study NCT05267587 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hypofractionated Stereotactic Radiosurgery
Description: Participants will be given hypofractionated stereotactic radiosurgery (fSRS) in 9 Gray Units (Gy) per fraction x 3 consecutive daily fractions (27 Gy total) to the index metastasis that will be resected.
Study NCT04457076 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LevoCept
Description: Levonorgestrel-Releasing Intrauterine System
Study NCT05855941 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: FDG-PET/CT and FDG-PET/MRI
Description: Intravenous injection of FDG 3 MBq/kg. Intravenous injection of Dotarem 279.3 mg/ml, 0.2 ml/kg.
Study NCT06480513 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: live yoga
Description: following live yoga classes twice a week and using yoga video's at home once a week
Study NCT06480513 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: live remote yoga
Description: The control group will be offered live remote yoga classes after the intervention period
Study NCT04500041 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Casting
Description: Use of casts applied using corrective maneuvers
Study NCT04500041 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bracing
Description: Use of full-time spinal orthosis
Study NCT06038825 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: topical vibration
Description: topical vibration (Aprilla brand, giving 6000 vibrations per minute) is a device for pain relief during injection of local anesthetic.
Study NCT05739942 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [177Lu]Lu-NeoB
Description: Radiopharmaceutical solution for infusion
Study NCT05739942 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [68Ga]Ga-NeoB
Description: Either provided as Kit for the radiopharmaceutical preparation of \[68Ga\]Ga-NeoB or as ready to use radiopharmaceutical solution for injection
Study NCT05739942 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Capsules/ lyophilized powder in single-dose vial for reconstitution.
Study NCT05977946 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Volta System
Description: The Volta System is a wearable, battery-operated, neurostimulation system designed to deliver tAN or taVNS. The device will be used to deliver two 30-minute sessions of active or sham therapy according to the participant's randomization group (taVNS or tAN).
Study NCT06105788 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Arm exercise will be an arm ergometer for 20 minutes, preceded by a 5-minute warm-up.~Leg exercise will be a cycling ergometer for 20 minutes, preceded by a 5-minute warm-up.~The exercise intensity will be set at 70% of the heart rate reserve (HRR) for each type of exercise.
Study NCT06105788 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: Arm exercise will be an arm ergometer for 20 minutes, preceded by a 5-minute warm-up.~Leg exercise will be a cycling ergometer for 20 minutes, preceded by a 5-minute warm-up.~The exercise intensity will be set at 70% of the heart rate reserve (HRR) for each type of exercise.
Study NCT05366920 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: dissection of gallbladder in laparoscopic cholecystectomy
Description: Laparoscopic cholecystectomy with diathermy hook starting from triangle of Calot
Study NCT05366920 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: dissection of gallbladder in laparoscopic cholecystectomy
Description: laparoscopic cholecystectomy with 5mm suction irrigation blunt dissection starting from fundus
Study NCT05958368 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Avocado
Description: The Hass Avocado group will consume 7 avocados a week (1 / day; \~240 kcals/d).
Study NCT05958368 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Other Fruit(s)
Description: The other fruits group will consume fruit(s) matched to the avocado in energy and form (i.e., solid fruit).
Study NCT05788822 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Mevalproic acid
Description: Methovalerate pathway is a metabolism of cholesterol and isoprenoid synthesized from acetyl coenzyme A Pathway, which plays a key role in human health and disease, is also necessary for human cells to maintain normal functions. There are a series of important metabolic intermediates in the mevalproate pathway, such as farnesyl diphosphate and incense Folyl vanillin diphosphates, which modify proteins through isoprene, play an important role in regulating cell function. In addition, the latest research shows that valproic acid, the key metabolic intermediate of valproic acid pathway, being the synthetic precursor of cholesterol and isoprene, it can activate insulin growth factor (IGF)1-R and mTOR signals and maintain cell function by mediating histone function
Study NCT06343012 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Caring leadership Intervention program
Description: Caring leadership intervention program
Study NCT06343012 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Caring leadership Intervention program
Description: Caring leadership intervention program
Study NCT05746481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tiragolumab
Description: Tiragolumab (an investigational novel immune checkpoint inhibitor): 600 mg IV for induction treatment administered on Day 1 of each 21-day cycle for 4 cycles. Maintenance therapy will continue with tiragolumab on Day 1 of each 21-day cycle.
Study NCT05746481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab (monoclonal antibody): 1200 mg IV administered on Day 1 of each 21-day cycle.
Study NCT05746481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Pemetrexed (antifolate antineoplastic agent chemotherapy): 500 mg/m2 administered IV on Day 1 of each 21-day cycle.
Study NCT05746481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Carboplatin AUC 5 (alkylating agent chemotherapy): injection administered on Day 1 of each 21-day cycle.
Study NCT06335524 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Finger puppet
Description: The intervention group will receive finger-puppets and additional training pertaining to infant parent interaction and developmentally appropriate infant communication training.
Study NCT06335524 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bookworm reading intervention training and routine EDI care.
Description: Routine EDI care including Bookworm training.
Study NCT06335524 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Bookworm reading intervention training and routine EDI care.
Description: Routine EDI care including Bookworm training.
Study NCT04997187 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Bacillus coagulans group
Description: Bacillus coagulans 400 mg/day for 12 weeks
Study NCT04997187 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: Placebo 400 mg/day for 12 weeks
Study NCT05200104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PXL065
Description: PXL065 22.5 mg QD
Study NCT04582370 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: theater program
Description: 10-week theory-based theater program designed to improve their physical functioning and reduce emotional stress.
Study NCT05615844 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotic Cement Bead Pouch
Description: The antibiotic bead pouch provides an antibiotic delivery mechanism. It is made by combining polymethyl methacrylate (PMMA) cement with generic forms of vancomycin and tobramycin powder.
Study NCT05615844 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Negative Pressure Wound Therapy
Description: Standard application of negative pressure wound therapy
Study NCT05589064 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Dietetic counseling
Description: Patients will receive dietary counselling to increase caloric and nutrient intake, stabilize glycemia, and optimize hydration.
Study NCT05589064 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Active Comparator: Omega-3, vitamin D3 and creatine monohydrate
Description: Patients will be prescribed dietary supplements which will be taken daily for 8 weeks, as per the supplement protocol.
Study NCT05589064 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: Omega-3, vitamin D3 and creatine monohydrate
Description: Patients will be prescribed dietary supplements which will be taken daily for 8 weeks, as per the supplement protocol.
Study NCT05589064 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Other : Physiotherapy treatment
Description: Patients will receive weekly physiotherapy treatment.
Study NCT05589064 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Other : Physiotherapy treatment
Description: Patients will receive weekly physiotherapy treatment.
Study NCT05589064 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Other : Physiotherapy treatment
Description: Patients will receive weekly physiotherapy treatment.