AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04697004 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Investigational Arm: SMR Stemless Reverse
Description: The SMR Stemless Reverse is intended for total, primary shoulder joint replacement by reducing pain and restoring shoulder articular mobility function.
Study NCT04697004 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Control Arm: SMR Reverse Shoulder System
Description: Conventional stemmed shoulder prostheses are commonly used in the clinical practice.
Study NCT05831696 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Powered Microprocessor-controlled Knee (PMPK)
Description: A microprocessor-controlled Knee with standardized commercial prosthetic foot
Study NCT05709353 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prolonged exposure therapy
Description: COPE represents an integration of existing evidence-based manualised CBT interventions for PTSD and substance dependence (see manual DOI: 10.1093/med:psych/9780199334513.001.0001). COPE used in the current study will represent an integration of existing evidence-based manualised CBT interventions for PTSD and substance dependence. COPE only begins when the participant in a safe environment and no longer in contact with the traumatic event/exposure.~COPE employs imaginal and in vivo exposures to treat PTSD and consists of 12 individual 90-minute sessions (i.e. 19.5 hours) delivered by a clinical psychologist.
Study NCT06205641 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xuanfei Baidu Granule
Description: Take Xuanfei Baidu Granule 1 bag in the morning and evening with boiling water for 5 days.
Study NCT06205641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Baloxavir Marboxil Tablet
Description: Take Baloxavir Marboxil Tablet 2 tablets orally, once a day, for 1 day.
Study NCT05709353 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Prolonged exposure therapy
Description: COPE represents an integration of existing evidence-based manualised CBT interventions for PTSD and substance dependence (see manual DOI: 10.1093/med:psych/9780199334513.001.0001). COPE used in the current study will represent an integration of existing evidence-based manualised CBT interventions for PTSD and substance dependence. COPE only begins when the participant in a safe environment and no longer in contact with the traumatic event/exposure.~COPE employs imaginal and in vivo exposures to treat PTSD and consists of 12 individual 90-minute sessions (i.e. 19.5 hours) delivered by a clinical psychologist.
Study NCT05709353 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MDMA
Description: Administration of 80 to 160 mg MDMA across two 'dosing' sessions. Supplemental doses (additional 40mg during first session, additional 40- 80mg during second session) will be dependent on clinician and participant consensus during preparatory period of 'dosing session'. These supplemental amounts will be dispensed 60 to 90 minutes after initial 80 mg dose.
Study NCT05709353 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Niacin
Description: Administration of niacin 250mg or niacin-matched placebo during two 'dosing' sessions.
Study NCT05146960 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Temporal summation
Description: Temporal summation will be evoked in each predetermined area
Study NCT05146960 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: PPTs will be assessed once in each predetermined area
Study NCT06038903 — intervention group
Intervention type: OTHER
Intervention: caffeine consumption expectation
Description: The group to which the Short-form caffeine expectation questionnaire (B-CaffeQ) was applied, which evaluated the expectations from caffeine consumption.
Study NCT06236360 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mediterranean Diet Intervention
Description: The primary goal is to evaluate whether tele-intervention can elevate the level of flavonoids, anthocyanins, proteins, omega-3 fatty acids, short fatty acids, fruits and vegetables, and fibers (all previously associated with a better response to immunotherapy) and limit foods with added sugars.
Study NCT05739032 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aerobic exercise and strength training
Description: Aerobic Exercise Training: The individuals in the study group were given aerobic exercise training at 70-80% of the 6MWT average speed. Patients performed exercise three days per week (twice under the supervision of a physiotherapist and once at home) for 30 minutes a day.~Strength Training: Lower and upper extremity strengthening training was performed three days a week, 3x10-12 repetitions per day, with the help of a resistance band suitable for muscle strength. Hip flexion, hip abduction, knee flexion, and knee extension exercises for the lower extremity, and shoulder flexion, shoulder extension, shoulder abduction, shoulder elevation, external rotation, horizontal shoulder abduction, and scapular adduction exercises for the upper extremity were performed.
Study NCT04868643 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: The DIMI Renal Replacement Therapy (RRT) System
Description: To demonstrate that the safety and efficacy of the DIMI RRT remains consistent when used In-Center by trained dialysis nurses versus in an In-Home environment by trained Care Partners and Subjects.
Study NCT06408922 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: prp injection
Description: intraarticular prp
Study NCT04873297 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metoclopramide 10mg
Description: Tab. Metoclopramide 10mg TDS via NG tube
Study NCT04873297 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 10 ml of plain water Via NG
Study NCT05114161 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Novel Care Pathway
Description: The novel care pathway will follow a decision tree based on several criteria to stratify patients in an appropriate risk category. Patients with large radiographic lobar consolidation OR POC CRP > 60mg/L will be deemed 'appreciable risk' while patients with CRP \< 20mg/L will be deemed 'low risk'. Patients with CRP between 20 - 60mg/L will be evaluated further, as follows: if they have an oxygen saturation of \<95%, they will be 'appreciable risk', and if not, there are further decision points: if they are not tachypneic, they will be 'low risk'; if they are tachypneic and less than 1 year of age, they will be 'appreciable risk'; if they are tachypneic, over 1 year of age, but with either complete PCV13 immunization OR detectable wheezing as per the ED clinician, they will be classified as 'low risk'. Appreciable-risk participants will be given a prescription for antibiotics at ED discharge.
Study NCT06306677 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: AI-clincial-based hybrid system for radiographic image analysis
Description: The Index test is a novel AI-clinical-based hybrid system for radiographic image analysis. Its diagnostic performance will be compared to the reference represented by a panel of experts.
Study NCT05804981 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: PRO-CS
Description: 4 questions about cognitive function added to annual wellness visit protocol
Study NCT06001827 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SelfWrap Bioabsorbable Perivascular Wrap
Description: SelfWrap is applied during arteriovenous fistula (AVF) creation surgery. It provides mechanical support to improve maturation and patency of AVFs.
Study NCT06001827 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Untreated AVF Control
Description: AVF creation surgery without any intervention
Study NCT04876651 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 177Lu-DOTA-rosopatamb
Description: Two single intravenous (IV) injections of 76 mCi each (equivalent to a 45 mCi/m2 dose in a standard 1.7m2 individual) of 177Lu-DOTA- rosopatamab, given 14 days apart, plus best SoC
Study NCT04876651 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: enzalutamide or abiraterone \[+ prednisone/prednisolone)\] or docetaxel
Study NCT05805683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcitonin
Description: patients in this group will receive 100 IU (1 ml) of calcitonin subcutaneously per day for 2 weeks starting within 48 hours after injury.
Study NCT05805683 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: patients in this group will receive 1 ml of saline placebo solution subcutaneously per day for 2 weeks starting within 48 hours after injury.
Study NCT06226142 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneous dilatational tracheostomy
Description: Percutaneous dilatational tracheostomy
Study NCT06226142 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Percutaneous dilatational tracheostomy
Description: Percutaneous dilatational tracheostomy
Study NCT05460221 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Optimized oil group
Description: This is a controlled parallel study. The patient will receive 25 mL/day of three different types of olive oils with different amouns of bioactive compounds from the olive tree, that must be consumed throughout the day at breakfast or snack (depending on the habits of each child). The doses that they do not take must be returned to the hospital staff to assess adherence to the intervention. The families will receive the same type of oil so that they can cook with it during the study period.~The control oil will be the same extra virgin olive oil washed to decrease bioactive components (approx. 125 ppm).~The intervention will take place for 6 months.
Study NCT05460221 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Functional oil group
Description: This is a controlled parallel study. The patient will receive 25 mL/day of three different types of olive oils with different amouns of bioactive compounds from the olive tree, that must be consumed throughout the day at breakfast or snack (depending on the habits of each child). The doses that they do not take must be returned to the hospital staff to assess adherence to the intervention. The families will receive the same type of oil so that they can cook with it during the study period.~The control oil will be the same extra virgin olive oil washed to decrease bioactive components (approx. 125 ppm).~The intervention will take place for 6 months.
Study NCT04787900 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iPhone measurement application
Description: The iPhone measurement application will be used to ensure validity and reliability.
Study NCT04787900 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bubble inclinometer
Description: Bubble inclinometer with proven validity and reliability will be used for this study.
Study NCT05460221 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: This is a controlled parallel study. The patient will receive 25 mL/day of three different types of olive oils with different amouns of bioactive compounds from the olive tree, that must be consumed throughout the day at breakfast or snack (depending on the habits of each child). The doses that they do not take must be returned to the hospital staff to assess adherence to the intervention. The families will receive the same type of oil so that they can cook with it during the study period.~The control oil will be the same extra virgin olive oil washed to decrease bioactive components (approx. 125 ppm).~The intervention will take place for 6 months.
Study NCT05250531 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: multicomponent therapy
Description: patient education,Exercise training,Private Psychotherapy,relaxation
Study NCT05250531 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: multicomponent therapy
Description: patient education,Exercise training,Private Psychotherapy,relaxation
Study NCT05081843 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: AD IT UP media literacy intervention
Description: AD IT UP was originally developed in 2006 as a classroom-based cigarette prevention program focused on traditional media influences, and was converted to a web-based program in 2011. In 2019, the AD IT UP program was updated substantially to include other forms of tobacco, such as e-cigarettes, and other forms of media, such as social media.
Study NCT05081843 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual health education curriculum
Description: The schools' regular health education curriculum includes classroom lectures, hands on activities and group work.
Study NCT05081843 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Usual health education curriculum
Description: The schools' regular health education curriculum includes classroom lectures, hands on activities and group work.
Study NCT04827082 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diacutaneous fibrolysis
Description: Diacutaneous fibrolysis is a physiotherapeutic instrumental technique, used to treat musculoskeletal conditions causing pain and/or movement restriction. It is applied by means of metallic hooks, ending in a spatula with beveled edges. Regardless of its own dominance, diacutaneous fibrolysis will be applied to de following muscles and intermuscular septums: gluteus maximus, biceps femoris and semitendinosus to de lower experimental limb. A single session of 10 minutes will be applied.
Study NCT05210465 — intervention group
Intervention type: OTHER
Intervention: speckle tracking mode of the stress ECHO test with dobutamine
Description: speckle tracking mode of the stress ECHO test with dobutamine
Study NCT04981834 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT04981834 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT04981834 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04981834 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT04981834 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radical Prostatectomy
Description: Undergo RARP
Study NCT04981834 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radical Prostatectomy
Description: Undergo RARP
Study NCT04981834 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vesicopexy
Description: Undergo vesicopexy
Study NCT06482723 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mGlobal L+AS
Description: The investigated dermal filler mGlobal L+AS is intended to be used as a temporary filler, administered by intradermal or subcutaneous injections, to correct small skin defects, such as wrinkles or scars.
Study NCT04079257 — intervention group
Intervention type: OTHER
Intervention: Blood collection for measurement of eculizumab peak concentrations
Description: collection of blood
Study NCT06492265 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Emergency Stroke Unit based on 0.23-T MRI
Description: The participants with hyperacute ischemic stroke (between 4.5-6 hours after onset of symptoms) who are eligible to receive reperfusion therapy will be managed by Emergency Stroke Unit process based on low-field magnetic resonance imaging.
Study NCT06492265 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Standard stroke unit adherent to guidelines
Description: The participants with hyperacute ischemic stroke (between 4.5-6 hours after onset of symptoms) who are eligible to receive reperfusion therapy will be managed by standard stroke unit process adherent to guidelines.
Study NCT05885295 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI brain, Blood tests, cognitive assessments
Description: observational study examining cognition post stroke using behavioural tests, MRI brain and blood tests
Study NCT05971134 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acupreesure applied
Description: Acupressure was applied to the LI4 acupuncture point for 3 minutes by the researcher for the intervention group
Study NCT04151875 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Extraction orthodontic treatment
Description: orthodontic treatment with teeth extraction
Study NCT04151875 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Non-extraction orthodontic treatment
Description: Non-extraction orthodontic treatment
Study NCT05262218 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PBF-680 10mg
Description: PBF-680 10mg administered orally once a day
Study NCT05262218 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo administered orally once a day
Study NCT05915013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Description: Intravenous ketamine
Study NCT05915013 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ketamine
Description: Intravenous ketamine
Study NCT05915013 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Perampanel
Description: Oral perampanel (6 mg)
Study NCT05915013 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Oral placebo
Study NCT06386068 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Values-based Cognitive Behavioral Therapy (V-CBT)
Description: The intervention offers a 10-session treatment for chronic Whiplash-Associated Disorder (WAD). The manualized adapted version of value-based cognitive behavioral treatment (V-CBT) is conducted by interdisciplinary teams of psychologists and physiotherapists. The program, based on V-CBT principles, focuses on psychoeducation, fostering self-efficacy, and setting value-based goals in the initial three sessions. The subsequent seven sessions involve physiotherapists trained in V-CBT, addressing psychological, physical, social, and practical barriers hindering engagement in participants' lives. Each session combines psychologically informed themes and supervised exercises, aiming to enhance engagement in values-based activities.
Study NCT06423963 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: Each participant will receive a Fitbit device with instruction and encouragement to self-monitor physical activity using step counts.
Study NCT06423963 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nutrition Counseling
Description: Participants will receive nutritional counseling with a registered dietician.
Study NCT06423963 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resistance Training
Description: Participants will engage in progressive, full-body resistance training based on American College of Sports Medicine (ACSM) guidelines.
Study NCT04789291 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1595043
Description: Single dose of 30 milligram (mg) BI 1595043 as film coated tablets (1x 5mg tablet and 1x 25mg tablet).
Study NCT05622682 — intervention group
Intervention type: OTHER
Intervention: Observational only: Serology and flow cytometry for ALL cohort participants
Description: Blood samples from ALL cohort participants will be tested to measure antibodies to vaccine-preventable diseases and immune recovery
Study NCT05622682 — intervention group
Intervention type: OTHER
Intervention: Observational only: Infection rates
Description: Number of infections during the study period will be obtained from both ALL cohort and healthy control participants and captured for comparison and evaluation of infection rates during the first year off-chemotherapy.
Study NCT05748392 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Wound and per-wound assessments While using Device
Description: 3D imaging and wound and per-wound skin characteristics will be conducted initially, at dressing changes and at end of treatment/study.
Study NCT06144736 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Robot-assisted retroperitoneal lymph node dissection
Description: Robot-assisted, if possibe ipsilateral nerve-sparing, retroperitoneal lymph node dissection and metastasis resection in a unilateral dissection field (template)
Study NCT06144736 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin
Description: The patient is given the option for an adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin two to four weeks after RA-RPLND
Study NCT04738097 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ticagrelor 90mg
Description: ASA 325 mg stat and ticagrelor 180 mg stat, then ASA 80 mg daily and ticagrelor 90 mg BID for 21 days.Treatment will be continue with ASA 80 until 3 months.
Study NCT04738097 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Clopidogrel 75 mg
Description: ASA 325 mg stat and clopidogrel 300 mg stat, then ASA 80 mg and clopidogrel 75 mg daily for 21 days.Treatment will be continue with ASA 80 until 3 months.
Study NCT06302231 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dietary and Exercise Approaches
Description: Intermittent fasting plus energy restriction combined with aerobic exercise performed in a fasted state.
Study NCT06302231 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Dietary and Exercise Approaches
Description: Intermittent fasting plus energy restriction combined with aerobic exercise performed in a fed state.
Study NCT06302231 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Dietary Approach
Description: Intermittent fasting plus energy restriction without aerobic exercise training.
Study NCT06325878 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Genome-wide association study
Description: Alleles/haplotypes evidence through GWAS will be compared between patients with CIDP and control subjects without CIDP