AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06042140 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NEOX Cord 1K applied fetoscopically
Description: Under general anesthesia and tocolysis, in-utero repair begins with a laparotomy that is followed by exteriorization of the uterus. The fetus is then positioned by external cephalic version. Uterine entry will be accessed using 3 cannulas, followed by heated-humidified carbon dioxide insufflation for visualization. Then, fetoscopically the placode will be examined and dissected. The lesion will be repaired using NEOX Cord 1K® (HUC) for closure of the first layer over the neural placode. Primary closure of the skin will then occur, or NEOX Cord 1K® (human umbilical cord) will be used for skin closure at the discretion of the Pediatric Neurosurgeon. Finally, the laparotomy site will be sutured in multiple layers.
Study NCT04802837 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ridinilazole
Description: Ridinilazole 200mg dosed BID for 10 days.
Study NCT04802837 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: Vancomycin 125mg dosed QID for 10 days.
Study NCT04827355 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: External Upper Esophageal Sphincter (UES) Compression Device
Description: External Upper Esophageal Sphincter (UES) Compression Device fit to manufacturer guidelines.
Study NCT04827355 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham Device
Description: External Upper Esophageal Sphincter (UES) Compression Device fit to pressure known not to provide treatment.
Study NCT06498921 — intervention group
Intervention type: OTHER
Intervention: Darolutamide (Nubeqa, BAY1841788) in combination with androgen deprivation therapy (ADT) and docetaxel
Description: No treatment will be provided to participants in the study. The decision on initiation of darolutamide (Nubeqa, BAY1841788) in combination with ADT and doctaxel and duration of treatment is solely at the discretion of the treating physician, guided by the recommendations outlined in the local product information.
Study NCT05338008 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intrawound administration of vancomycin after closure of the arthrotomy
Description: After closure of the arthrotomy, 1 g of vancomycin powder suspended in 30ml of normal saline was injected directly into the joint with an 18-gauge needle.
Study NCT04628117 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oral nutritional supplementation for kidney disease
Description: 237 mls per day for 8 weeks.
Study NCT05592340 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure to calorie information
Description: Calories for all foods and beverages
Study NCT05519150 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: low dose radiation abdomen/pelvis CT scan (stone protocol)
Description: Kidney donors who consent will undergo a low dose radiation abdominal CT scan to identify new kidney stones in the remaining kidney. The will come to an IU Health Hospital for a low dose radiation abdomen/pelvis CT scan (stone protocol).
Study NCT05519150 — intervention group
Intervention type: PROCEDURE
Intervention: Blood draw
Description: To compare the changes changes in eGFR in evaluated kidney donors Blood will be draw by a trained phlebotomist.
Study NCT06432439 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: microneedling followed by CAF procedures
Description: microneedling will be done on gingiva of RT1 recession tooth in 4 sessions followed by CAF 2months later for root coverage
Study NCT05592340 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Exposure to calorie information
Description: Calories for all foods and beverages
Study NCT06432439 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: CAF procedure
Description: RT1 gingival recession coverage by CAF procedures alone.
Study NCT04739709 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APP13007, 0.05%
Description: APP13007 eye drop, 0.05%
Study NCT04739709 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Vehicle Placebo for APP13007, 0.05%
Description: Matching vehicle placebo eye drop
Study NCT05410067 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cervicothoracic Junction Mobilization Technique
Description: It is a part of manual therapy technique. Patient would be in prone position with his forehead in the palm of the therapist. Maitland mobilization to the C7- T1 level, according to their primary movement restriction (for flexion-extension restriction- central PA glide, for rotation restrictions unilateral PA glide) is given. For central PA glide, a central pressure angled towards the participant's head was given with overlapping thumbs of the therapist placed on the spinous process of C7. The therapist's thumbs were placed on the posterior surface of the articular process to be mobilized (C7 on the side of restriction), and anteriorly directed oscillatory pressure was applied for unilateral PA mobilization.
Study NCT05410067 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Eccentric Muscle Energy Technique
Description: Eccentric muscle energy technique would be applied to the patient's cervical spine. The cervical spine would be brought to the barrier of motion in each plane i.e. flexion/extension, lateral bending and rotation. Then patient would be asked to push their heads into the direction opposite that of the barrier.
Study NCT02860078 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound
Description: Location and function of sacral epidural space with ultrasound
Study NCT02860078 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radioscopy
Description: Location and puncture of the sacral epidural space only with fluoroscopy
Study NCT06377917 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Laser Assisted Hatching
Description: Routine assisted hatching procedure will be performed on both groups at the different embryo developmental phases.
Study NCT06377917 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Laser Assisted Hatching
Description: Routine assisted hatching procedure will be performed on both groups at the different embryo developmental phases.
Study NCT05519150 — intervention group
Intervention type: OTHER
Intervention: 24 hour urine collection
Description: To compare the changes in metabolic kidney stone risk parameters in 24-hour urine assessments to pre-donation urine studies in evaluated kidney donors.
Study NCT05878483 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Venipuncture Device (VD)
Description: The Venipuncture Device is a pre-market medical device that fully automates the blood drawing procedure (also called phlebotomy or venipuncture). It automatically detects a vein using near-infrared and ultrasound imaging technology, robotically inserts a needle, automatically connects blood tubes and applies pressure to the puncture site.~During the ADOPT Study, the technology is further improved over time; for example features are released (such as: automated tourniquet). Initially, several manual steps are required to be performed by a device supervisor and operator. At the final stage of the ADOPT Study, Phase C2, the device has full functionality and only limited manual steps are required to be performed by a device supervisor.
Study NCT06439680 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: HASCV-R Health Programme
Description: HASCV-R program Healthy nutrition, Active life, Ways to cope with Stress, Cancer and cancer screening, Vaccination - Reproductive health Training programme
Study NCT06439680 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: HASCV-R Health Programme
Description: HASCV-R program Healthy nutrition, Active life, Ways to cope with Stress, Cancer and cancer screening, Vaccination - Reproductive health Training programme
Study NCT04100057 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy for Insomnia (CBT-I)
Description: CBT-I improves sleep through a combination of behavioral interventions (stimulus control (SC), sleep restriction (SR)), cognitive therapy (CT) as well as additional components such as mindfulness training and sleep hygiene education. SC is an intervention that re-establishes the connection between the bed/bedroom with sleep to help develop a more consistent sleep/wake pattern. SR leads to higher quality sleep by reducing excessive time spent in bed to the actual amount of sleep, thereby creating mild sleep deprivation and increasing the homeostatic sleep drive. Like CT for other disorders, CT for insomnia targets maladaptive thoughts and cognitions that may interfere with sleep.
Study NCT04100057 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Desensitization Therapy for insomnia (DT-I)
Description: DT-I is a quasidesensitization treatment presented as a means of eliminating the conditioned arousal, which prolongs nocturnal awakenings. DT-I has been validated as an active-placebo control condition. Therapists help each DT-I recipient develop a chronological 12-item hierarchy of common activities he/she does on awakening at night (e.g., opening eyes, clock watching). Therapists also help them develop 6 imaginal scenes of themselves engaged in neutral activities (e.g., reading the newspaper). Each session, DT-I recipients are taught to pair neutral scenes with items on the 12-item hierarchy so, by the end of the sixth session, all hierarchy items have been practiced with therapist assistance. Each session, the exercise is tape recorded and the patient is given this tape locked in a player. The patients are told to practice their exercises at home once each day, no less than 2 hours before bedtime, but to avoid using the tape or exercise during sleep periods.
Study NCT05592340 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exposure to carbon footprint information
Description: Carbon footprint labels for all foods and beverages
Study NCT04698876 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Self-tonometry by means of ICareHOME
Description: Outpatient measurement of intraocular pressure at home
Study NCT04698876 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intraocular measurement by means of rebound tonometry or Goldmann applanation tonometry
Description: Stationary measurement of intraocular pressure in a clinic
Study NCT04698876 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Blood pressure
Description: Blood pressure measurement for 24 h
Study NCT04698876 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Blood pressure
Description: Blood pressure measurement for 24 h
Study NCT05931783 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: skeletonized harvesting technique
Description: In patients who are randomized to this treatment arm, the left internal thoracic artery will be harvested in skeletonized technique. Thereby, only the artery itself is harvested.
Study NCT05931783 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: pedicled harvesting technique
Description: In patients who are randomized to this treatment arm, the left internal thoracic artery will be harvested in pedicled technique. Thereby, the artery will be harvested together with the accompanying veins, the endothoracic fascia and fatty tissue in order to create an 1-2 cm broad pedicle.
Study NCT05154474 — intervention group
Intervention type: OTHER
Intervention: Standard
Description: Standard follow-up with clinical exams, functionnal test at baseline, Ct scan MNA, IPAQ, SARC-F and SarQOL questionnaires
Study NCT05211167 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Human Erythropoiesis Injection (CHO cell)
Description: Human Erythropoiesis Injection (CHO cell) is a recombinant human erythropoietin with the same biological effects as natural erythropoietin
Study NCT05211167 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant Erythropoiesis Stimulating Protein Injection(CHO cell)
Description: rESP is a high glucose medium and long-acting recombinant protein products, containing 165 amino acids by adding 3 glycosylation sites
Study NCT05102565 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sleep education program
Description: A multicomponent behavioral sleep program, consisting of sleep hygiene, stimulus control, sleep compression, pleasurable activity, daily walking, and light exposure.
Study NCT04733885 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental
Description: Current application will be made in the frequency range of 20-50 Hz. The Chattanooga (Intelect Neo) device with interfering current will be used for treatment, vacuum electrodes will be made in the form of 4 pole application. Two electrodes to the outside of the inguinal ligament, the other two electrodes will be placed on the upper inner part of the thigh.ES applications will be performed in the supine position with head and knee pillow supported.
Study NCT04733885 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Control
Description: The Chattanooga (Intelect Neo) device with interfering current will be used for treatment, vacuum electrodes will be made in the form of 4 pole application. Two electrodes to the outside of the inguinal ligament, the other two electrodes will be placed on the upper inner part of the thigh. The same device used in ES application to the sham group will be attached to the patients, however, active ES will not be issued from the device and only vacuum will turn on. ES applications will be performed in the supine position with head and knee pillow supported.
Study NCT06255548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Immersive virtual reality group
Description: The children in the IVR group were offered two video games from the Oculus Quest gallery. These games were Ocean Rift and Epic Roller Coaster-T-Rex Kingdom. Ocean Rift is the world's first VR water safari park. It has 12 different marine animals such as dolphins, sharks, and turtles and a habitat. Here one can visit a vibrant underwater world that extends all the way to the Arctic and Atlantis. Epic Roller Coaster-T-Rex Kingdom takes one on a roller coaster ride through the Age of Dinosaurs. There are more than 10 species of dinosaurs such as terrestrial, flying, herbivorous and carnivorous.
Study NCT06255548 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music group
Description: In musical interventions, it is recommended to play music chosen by individuals. Disposable ear pads were used for each child and the headphones were cleaned after each intervention.
Study NCT06323993 — intervention group
Intervention type: PROCEDURE
Intervention: Piezoelectric osteotomy
Description: The piezoelectric technique, another window preparation procedure that does not use a round bur, was first introduced to LSFE in 2001 for its high accuracy of osteotomy and low rate of membrane perforation. Later studies demonstrated that the operation time, postoperative reactions, and perforation rate of this procedure are considered to be acceptable compared with rotary bur. Moreover, the piezoelectric technique allows for the lateral bone window to be cut and preserved relatively completely.
Study NCT05202951 — intervention group
Intervention type: OTHER
Intervention: questionnaires
Description: Electronic case report form integrating questionnaires on chronic pain related to haemophilia, associated-comorbidities, sociodemographic characteristics and analgesic treatments used.
Study NCT05548374 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: The acupoints of Shangyintang, Danzhong(RNl7), Jvque(RN14), Liangmen(ST21), Zhongwan(RNl2), Hegu(LI4), Waiguan(SJ5), Zusanli(ST36), Sanyinjiao(SP6), Taichong(LR3) are selected as main acupoints and used per treatment. The other three acupoints will be chosen one each session according to the syndrome differentiation: Taixi (KI3) for liver and kidney deficiency, Fenglong (ST40) for spleen deficiency and phlegm coagulation, and Xuehai (SP10) for qi-stagnation and blood-stasis. Sterile adhesive pads will be placed on the acupoints after skin disinfection. Hwato-brand disposable acupuncture needles (size 0.30×40mm) will be inserted into the acupoints through the adhesive pads. Afterwards, the acupuncture will be lifted, thrusted and twirled gently for 3 times to achieve deqi sensation and manipulated every ten minutes during 30-minute maintenance.
Study NCT05548374 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture
Description: The acupoints of Shangyintang, Danzhong(RNl7), Jvque(RN14), Liangmen(ST21), Zhongwan(RNl2), Hegu(LI4), Waiguan(SJ5), Zusanli(ST36), Sanyinjiao(SP6), Taichong(LR3) are selected as main acupoints and used per treatment. The other three acupoints will be chosen one each session according to the syndrome differentiation: Taixi (KI3) for liver and kidney deficiency, Fenglong (ST40) for spleen deficiency and phlegm coagulation, and Xuehai (SP10) for qi-stagnation and blood-stasis. Sterile adhesive pads will be placed on the acupoints after skin disinfection. The needles (with the handle identical to the needles in the acupuncture group and the body at a size 0.30 × 25 mm) will be inserted into adhesive pads without skin penetration. Needles will be lifted, thrusted and twirled gently for 3 times to mimic real acupuncture. No manipulation will be conducted during 30-minute maintenance.
Study NCT06532773 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nite2Day+
Description: Mindfulness-based sleep strategies and cognitive-behavioral symptom coping skills.
Study NCT06355349 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Reference Drug or Test Drug
Description: Tablet, Oral, QD for 1 Day, Washout period is more than 21 days after administration
Study NCT06381583 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EMERALD (Esophageal MicroRNAs for BaRRett's esophagus, Adenocarcinoma, and Dysplasia)
Description: A panel of circulating microRNA, whose expression level is tested in cell-free derived samples.
Study NCT04755985 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AD-213-B
Description: 1 tablet administered before the breakfast during 5 days
Study NCT04755985 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AD-2132
Description: 1 tablet administered before the breakfast during 5 days
Study NCT05835700 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Gasdermin-d
Description: Maternal serum Gasdermin-D levels in preterm labor and healthy pregnant women.
Study NCT05057702 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Specialized Tumor Board Treatment Plan
Description: Specialized Treatment Plan of up to four FDA approved drugs based on participant's screening results will be assigned by PNOC specialized tumor board
Study NCT06475924 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Caesarean scar defect evlauation by ultraosund
Description: Women will be examined in the lithotomy position with an empty bladder. The uterus will be examined in a standardized way excluding causes of abnormal uterine bleeding or pelvic pain (myoma, polyp, pelvic inflammatory disease, adenomyosis).~Upon detection of the SCD, the following will be measured:~In the midsagittal plane: the depth (the vertical distance between the base and apex of the defect), width (the length of the widest gap along the cervicoisthmic canal), residual myometrial thickness (RMT) overlying the defect, and the adjacent myometrial thickness fundal to the defect.~In the transverse plane: the length of the defect.~The uterine position will be classified as anteverted or retroverted.~Clinical symptoms of the patients will be reviewed such as :Postmenstrual spotting, Abnormal uterine bleeding, Pain, Secondary infertility.
Study NCT06215976 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin Hydrochloride 500 MG
Description: Metformin 500mg tablets twice daily
Study NCT04988464 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep Scholar
Description: A single-session, internet-based insomnia intervention for college students
Study NCT04988464 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Building Healthy Habits
Description: A single-session, self-guided, internet-based intervention focused on healthy eating and exercise
Study NCT05378724 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hospital Fit 2.0, HFITAPP0, release 05, Maastricht Instruments B.V., the Netherlands
Description: Hospital Fit consists of a smartphone app combined to the MOX accelerometer. Hospital Fit provides patients and physiotherapists direct feedback on patients' physical activity behavior. Individual goals regarding the number of minutes per day spent walking can be set by the therapist. Hospital Fit also gives patients insight into their own recovery process. During every treament, the physiotherapist will evaluate the extent of functional recovery. In addition, Hospital Fit will give physiotherapists the option of creating a patient-specific exercise program supported by videos. During every treatment session, the patient and physiotherapist will evaluate (and if necessary adapt) the amount of activity performed since the previous treatment, the extent of functional recovery and the exercise program.
Study NCT05884190 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Remote Medical Model (RMM)
Description: Remote home blood pressure (BP) monitoring once a day for the first 7 days and then at least weekly or more frequently as per a standardized blood pressure protocol up to six weeks and weekly virtual visits for 6 weeks and up to 12 weeks as needed by a physician extender (e.g. Nurse Practitioner, Pharmacist, etc.), and screening for social determinants of health and anxiety/ depression with referral for services if positive
Study NCT05884190 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Community Health Model (CHM)
Description: Utilization of community health workers trained in a strength-based trauma informed dyadic evidence-based approach.
Study NCT05884190 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SoC
Description: SoC for Postpartum Hypertension
Study NCT05884190 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SoC
Description: SoC for Postpartum Hypertension
Study NCT05200663 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tab Tamoxifen 10 mg
Description: Tablet tamoxifen 10mg twice a day for 6 months.