AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04859751 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VB4-845 Injection
Description: Intravesical administration of VB4-845 Injection.
Study NCT05824533 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: onlay patella button
Description: Total knee arthroplasty (TKA) with a patella onlay button placed with a CORI Robotics System based on pre-operative 4DCT-imaging.
Study NCT05824533 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional procedure; NO onlay patella button
Description: Total knee arthroplasty (TKA) placed with a CORI Robotics System based on pre-operative 4DCT-imaging.
Study NCT05629806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin plus pioglitazone
Description: After the screening period, eligible subjects were admitted to two tablets of fixed mixture of metformin plus pioglitazone (15mg pioglitazone plus 500mg metformin) for 12 weeks. Then the subjects were titrated onto the alternative treatment of 50mg acarbose three times daily for 12 weeks. During this timeframe, all patients were instructed to monitor their blood glucose fluctuations with a FreeStyle Libre Pro Sensor (FGM system) before and after the study and the time point of drug replacement.
Study NCT06325007 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Induction of labor
Description: The study group only will drink a mixture of 60 ml of castor oil mixed with 140 ml of orange juice. Thirty minutes later, in both groups, an extraamniotic single balloon catheter will be inserted above the internal cervical os and filled with 60 mL of normal saline. Following removal, artificial rupture of the membranes will be performed as long as it is safe with regards to fetal head position. Oxytocin infusion will be commenced at once if contraction has not begun spontaneously (2 to 3 regular uterine contractions per 10 minutes). Continuous electronic fetal monitoring will be used throughout labor. Labor will be managed by the attending obstetricians and midwives. Labor progress abnormalities will be diagnosed and managed according to the department protocol based on the recommendations of the American College of Obstetricians and Gynecologists.
Study NCT05891483 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1905 Injection
Description: SHR-1905 Injection
Study NCT05891483 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: SHR-1905 Placebo Injection
Description: SHR-1905 Placebo Injection
Study NCT05064033 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pragmatic Set of intervention and posterior capsular stretch
Description: Group 1 will receive a pragmatic set of interventions, including Serratus Anterior Stretch,Rotator Cuff Facilitation,Acromilcalavicular joint Mobilization,Stretch of Pectoralis Major and Minor,Thoracic Manipulation and posterior capsular stretch.
Study NCT05064033 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pragmatic Set of intervention and Sleeper Stretch
Description: Group 2 will receive a pragmatic set of interventions, including Serratus Anterior Stretch, Rotator Cuff Facilitation, Acromilcalavicular joint Mobilization, Stretch of Pectoralis Major and Minor, Thoracic Manipulation and sleeper stretch.
Study NCT05319795 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Effortful Swallow Maneuver
Description: Repeated practice of the Effortful Swallowing Maneuver generated by pushing the tongue with increased effort against the palate at the point of swallow initiation.
Study NCT04682184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propranolol
Description: Administered orally.
Study NCT04682184 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pseudoephedrine
Description: Administered orally.
Study NCT04682184 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Wearable Biosensor Patch Device
Description: Biosensor patch device attached to the chest and worn throughout the trial with replacement of biosensor every 7 days.
Study NCT05629806 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acarbose
Description: After the screening period, eligible subjects were admitted to 50mg acarbose three times daily for 12 weeks. Then the subjects were titrated onto the alternative treatment of two tablets of fixed mixture of metformin plus pioglitazone (15mg pioglitazone plus 500mg metformin) for 12 weeks. During this timeframe, all patients were instructed to monitor their blood glucose fluctuations with a FreeStyle Libre Pro Sensor (FGM system) before and after the study and the time point of drug replacement.
Study NCT04345588 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexamethasone injection
Description: we use injection lignocaine 10 mL, injection bupivacaine 0.5% 20 mL, 5 mL normal saline (NS). In group , injection dexamethasone 0.05 mg/kg will be added to the solution along with IV NS 1cc while the other group will receive 0.05 mg/kg injection dexamethasone intravenously.
Study NCT05458544 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [177Lu]Ludotadipep 3.7 GBq
Description: Phase 1:~Patients will receive a single dose of 3.7 GBq of \[177Lu\]Ludotadipep~* Test article code/name: \[177Lu\]Ludotadipep~* Administration route: intravenous injection~* Total dose strength: 3.7 GBq~* Dosage form: solution for injection~Phase 2a:~Patients will receive 3.7 GBq of \[177Lu\]Ludotadipep every 8 \[±1\] weeks (4 to 6 times)~* Test article code/name: \[177Lu\]Ludotadipep~* Administration route: intravenous injection~* Total dose strength: 4 to 6 x 3.7 GBq~* Dosage form: solution for injection
Study NCT05446012 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: thyroid function tests
Description: blood sample for thyroid function tests (TSH,T3,T3,Anti peroxidase antibody, anti thyroglobulin antibody)
Study NCT06582992 — intervention group
Intervention type: OTHER
Intervention: RRBS
Description: Measure of genomic regions with differentially methylated profiles and differentially expressed protein
Study NCT04862910 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinect Based Virtual Reality Training
Description: The participant will receive the game instructions from the examiner.Protocol will be implemented 3 steps Warm Up phase Activity phase and cool down phase. The games will be played under the supervision and guidance of the therapist.Games are selected from Kinect games Kinect Sports Kinect Adventures and Your Shape Fitness Evolved. Three treatment sessions per week will be given to each participant. Total duration of each treatment session will be 45 Minutes.Participants will be instructed to walk outdoors for 30 Minutes daily. Routine Medication and routine diet will be continued.
Study NCT04862910 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: * They will be instructed to walk outdoors daily for 30 Minutes.~* They will continue their daily activities with a routine diet and routine Medication
Study NCT03455725 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: CardiAMP Cell Therapy System
Description: The CardiAMP Cell Therapy system consists of the CardiAMP Potency Assay, the Helix/Morph intramyocardial delivery catheter system, and the CardiAMP Cell Separator. The system allows the investigator to identify patients with a high chance to respond to im autologous stem cell therapy (using the CardiAMP Cell Potency Assay), to isolate the stem cells from a bone marrow harvest at the point of care (using the CardiAMP CS system), and to percutaneously inject the autologous cells into the myocardium using the Helix/Morph delivery catheters.
Study NCT03455725 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Treatment
Description: Patients will receive sham bone marrow procedure and a ventriculogram. A scripted sham percutaneous procedure will be performed
Study NCT05167799 — intervention group
Intervention type: DEVICE
Intervention: Cardiac Contractility Modulation (CCM)
Description: Patients will be implanted with CCM device according to indications, to improve Heart Failure symptoms and then enrolled in the Registry if they fullfil Inclusion and Exclusion Criteria (First of all if they are diagnosed with TTR Amyloidosis)
Study NCT01223053 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketoprofen 10% cream
Description: 100 mg (10%) in 1 gram of topical cream applied three times per day for 7 days. Safety follow up on day 14.
Study NCT01223053 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo cream containing identical constituents as the active comparator except for ketoprofen
Study NCT06506890 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Use of C-Polar coated HVAC Filter versus conventional HVAC Filter
Description: comparing the difference in reduction of bioaerosols between HVAC filters.
Study NCT05347849 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BPL-003
Description: A single dose of BPL-003 will be administered intranasally
Study NCT05347849 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A single dose of placebo will be administered intranasally
Study NCT04640805 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Protein supplementation
Description: Liquid protein fortifier (Similac) will be added at 1ml per 25ml of PDHM at 130ml/kg/day of feed volume.
Study NCT04640805 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Analysis with Miris Human Milk Analyzer
Description: PDHM macronutrient content will be analyzed using the Miris Human Milk Analyzer and PDHM with fat content of 3.8g/dL or higher will be selected and provided.
Study NCT05916794 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Cervical Retraction Exercises (MCRE)
Description: Group A includes Modified cervical retraction exercise The patient is in sitting OR standing position and faces the physical therapist. The MCRE program consisted of alternating head position( neutral, side bending and rotation) while pushing their chin backward patients maintained an upright posture and tried to pull back their shoulders while maintaining this retracted position patient side bend OR rotate their head respectively hold the position for 20 sec.subject performed 5 sets of 10 repetition for 3-4 days per week. Rest intervals of 30 seconds were provided after the completion of 10 repetitions for each pattern and between sets, respectively. The total duration of MCRE will be of approximately 15-20 minutes
Study NCT05916794 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Motor Control therapeutic exercise(MCTE)
Description: Motor control therapeutic exercises will be guided for the retraining of cervical muscles.it include craniocervical flexor exercise,craniocervical extensor exercise, co-contraction of flexors and extensor, a synergy exercise for retraining the strength of the deep neck flexors. Each of these four exercises will be performed for 3 sets of 8 to 10 repetitions, taking an approximate total duration of 15-20 minutes for, 3 days a week
Study NCT05421572 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Fibrotouch
Description: Fibrotouch will be performed showing the stiffness and fat content of liver
Study NCT05118867 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iPREPARED
Description: iPREPARED is a mobile health technology that can be accessed via the web, tablet, or phone. It contains a preparatory video that outlines what to expect during the hospitalization. Instructional videos and examples are provided for the patient and their recovery partner to use to do their own reorientation, distraction techniques, physical activity, and sleep hygiene.
Study NCT06160375 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: pain assessment after video assisted thoracoscopic lung surgeries
Description: a scalp needle with an extended tube will be inserted into the paravertebral space at the T4 level under thoracoscopic direct vision before closing the chest. One centimeter adjacent to the vertebrae will be inserted vertically 0.5 cm under the parietal pleura with the needle, and 20 ml 0.25% bupivacaine will be injected then the field will be observed for 5 min to make sure that there is no hemorrhage or hematoma.
Study NCT06356883 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IA Carboplatin + IA Caelyx
Description: Intraarterial infusion of carboplatin combined with liposomal doxorubicin
Study NCT05484284 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: two-stage primary total knee arthroplasty with low-dose antibiotics
Description: Briefly, investigators completely debrided all necrotic soft tissue in the first stage of the operation. The surgical site was flushed twice with hydrogen peroxide, iodine, and saline solutions. Then, the antibiotic-loaded cement spacer was inserted. After surgery, a 10-day course of intravenous organism-specific antibiotics or vancomycin was administered, followed by oral antibiotic therapy. Second-stage reimplantation was performed once there was no sign of infection. The spacer was removed and the new prosthesis was implanted without the use of antibiotic-containing bone cement.
Study NCT05548985 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midodrine Oral Tablet
Description: oral midodrine tablet (5 mg) 90 min before performing spinal block
Study NCT05548985 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Metoclopramide
Description: oral placebo (metoclopramide 10 mg tablet). 90 min before performing spinal block
Study NCT06356883 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IA Carboplatin + IA Etoposide Phosphate
Description: Intraarterial infusion of carboplatin combined with etoposide phosphate
Study NCT06105723 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pathway to Healthy Aging care
Description: The ICOPE-based personalized care planning comprises two home visits. In 1st visit, a comprehensive assessment proposed by the WHO-ICOPE model is conducted to identify eight possible health problems including malnutrition, reduced physical fitness, fall risk, cognitive decline, insomnia, pain, psychological distress and social loneliness. After health problem identification, each participant receives a personalized care prescription. 2nd visit adopts a goal-oriented empowerment 3-step cycle to personalize the care planning: 1) communicating assessment results to increase healthy self-awareness; 2) supporting setting person-directed goals to address health problems; 3) identifying health actions and personalizing goal setting to participants' contexts. The 12-week healthy aging empowerment comprises three core activities for healthy aging promotion, including interactive health education, health message broadcasts, and three case conferences for goal monitoring and health counseling.
Study NCT04580264 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: REINTERVENTION
Description: This self-applied online program will take three months and comprise 9 behavioural modules developed gradually, achieving the changes needed on eating and physical activity habits, supported by audiovisual instructions given by an hypertension specialist doctor.
Study NCT05843747 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sampling
Description: During thier bariatric surgery, samples of adipose tissue will be done
Study NCT06326294 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Thermal ablation
Description: Thermal ablative uses heat (100°C to 120°C) to cause localized tissue damage at the cervical transformation zone and destroy the abnormal epithelium.
Study NCT06326294 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: LOOP ELECTROSURGICAL EXCISION PROCEDURE
Description: Cervical tissue excision
Study NCT05582668 — intervention group
Intervention type: PROCEDURE
Intervention: Bariatric surgery
Description: Bariatric surgery
Study NCT05749042 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sintilimab
Description: Concurrent Chemoradiotherapy Based of Cisplatin Plus Sintilimab.
Study NCT05749042 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiotherapy
Description: Concurrent Chemoradiotherapy Based of Cisplatin
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Education
Description: Education about health benefits of physical activity, 2018 US Physical Activity Guidelines, assigned goals tailored to baseline step counts, and worksheet to develop action and coping plans (three of each)
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Education about health benefits of physical activity, 2018 US Physical Activity Guidelines, assigned goals tailored to baseline step counts, and worksheet to develop action and coping plans (three of each)
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Activity tracker
Description: Fitbit activity tracker and mobile app to provide ad libitum behavioral feedback and self-regulatory support
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Activity tracker
Description: Fitbit activity tracker and mobile app to provide ad libitum behavioral feedback and self-regulatory support
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Text messaging (random timing and selection)
Description: Four text messages/day at random times within a participant's availability window and drawn at random from one of three content libraries (move more \[40%\], sit less \[40%\], inspirational quotes \[20%\])
Study NCT05794178 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Text messaging (precision dosing)
Description: Up to four text messages/day within a participant's availability window, timed and selected from one of three content libraries (move more, sit less, inspirational quotes) based on a person-specific dynamic model and contextual data
Study NCT04420260 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Group A: oropharygeal spray and immunostimulant emulsion
Description: Intervention 1: Preparation in a liquid solution to be used for oropharyngeal spray, composed of 3 natural bioactive substances of routine use in humans, that feature homologous molecular structures to the native viral receptor.~Intervention 2. Preparation in an emulsion functional food presentation for oral administration, that contains the 8 bioactive compounds that have demonstrated antiviral activity and modulation of the inflammatory response recognized at the moment in the immune activation against the virus.
Study NCT04420260 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Group D:Placebo oropharyngeal spray + Placebo taken PO
Description: Intervention 1: Preparation in a liquid solution to be used for oropharyngeal spray, composed of Placebo substances of routine use in humans.~Intervention 2. Preparation in an emulsion presentation for oral administration that contains the Placebo compounds
Study NCT06259682 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Paradoxical Intention
Description: Paradoxical intention (PI). PI is described as instructing patients with sleep onset insomnia to try to remain awake for as long as possible rather than to focus on trying to fall asleep
Study NCT06129929 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hospital Jujutsu Group, HJJ Group
Description: The aim of this study, procedures, methodology, and the subject's rights were well explained to the eligible nursing staff according to the informed consent form. Written informed consent was obtained from each participant before data collection.
Study NCT06129929 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Hospital Jujutsu Group, HJJ Group
Description: The aim of this study, procedures, methodology, and the subject's rights were well explained to the eligible nursing staff according to the informed consent form. Written informed consent was obtained from each participant before data collection.
Study NCT06277648 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: PENG block
Description: PENG block was performed by the primary investigator (B.C) following proper skin disinfection with the patient in the supine position. Under the guidance of a low-frequency curvilinear ultrasound probe, the iliopubic eminence and the psoas tendon were identified, and local anaesthetic as 30 mL 0.375% bupivacaine was injected between the periosteum and psoas tendon following negative aspiration.
Study NCT06277648 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: SIFIB
Description: The high-frequency linear probe was placed medial to the anterosuperior iliac spine in a parasagittal orientation to visualize the bow tie appearance formed by the sartorius's internal oblique and iliacus muscles. The needle tip was placed under fascia iliaca through an in-plane approach, and local anaesthetic as 30 mL 0.375% bupivacaine was injected from the caudad to the cephalic direction.
Study NCT06508008 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: continuous negative pressure suction
Description: (1) Open the mouth with a tongue depressor; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) Insert a suction tube into the mouth to aspirate phlegm.
Study NCT06508008 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intermittent negative pressure sputum suction through oral pharyngeal airway
Description: (1) Insert the oropharyngeal airway parallel into the oral cavity; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) The suction tube is inserted into the deep oral cavity through the middle lumen of the oropharyngeal airway; (4) Intermittent negative pressure for suction and suction of sputum
Study NCT05754593 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Anti-Mullerian hormone (AMH) level
Description: Measure of Anti-Mullerian hormone (AMH) level by blood sample
Study NCT05754593 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-Mullerian hormone (AMH) level
Description: Measure of Anti-Mullerian hormone (AMH) level by blood sample