AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SOC-REC/SOC-OIC
Description: Standard of care - routine education and counseling (SOC-REC)/SOC-Outreach and Intensified Counseling (OIC). SOC-REC is a stage 1 intervention to prevent lapses in HIV engagement through routine care. If an adolescent (1) misses an appointment >14 days, or (2) who have unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. SOC-OIC is a stage 2 intervention to treat lapses in HIV engagement through routine care which may include tracing and counseling to return to the clinic.
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SOC-REC/CCT
Description: SOC-REC/Conditional Cash Transfer (CCT). SOC-REC is a stage 1 intervention to prevent lapses in HIV engagement through routine care. If an adolescent (1) misses an appointment >14 days, or (2) who have unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. CCT is a stage 2 intervention to treat lapses in HIV engagement by providing a small cash incentive for on-time clinic attendance and/or viral load suppression (following per current MOH guidelines).
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SOC-REC/IP-NAV
Description: SOC-REC/In-Person Peer Navigation (IP-NAV). SOC-REC is a stage 1 intervention (routine care) to prevent lapses in HIV engagement. If an adolescent (1) misses an appointment >14 days, or (2) who have unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. IP-NAV is a stage 2 intervention to treat lapses in HIV engagement. Trained peer navigators will develop rapport with the participants and provide psychosocial support, case management, and assess retention and adherence barriers in a systematic manner and work with the participant to develop social support and clear, feasible plans to address barriers. The peer navigator will meet with the participant at least monthly, and no more than weekly, until HIV care engagement is demonstrated.
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: E-NAV/SOC-OIC
Description: E-Nav is a stage 1 intervention to prevent lapses in HIV engagement. Trained e-peer navigators will develop rapport and provide support through phone calls and/or patient preferred social media platforms. They will meet once in person and then weekly electronically for 8 weeks, and then monthly. If an adolescent (1) misses an appointment >14 days, or (2) who have unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. SOC-OIC is a stage 2 intervention to treat lapses in HIV engagement through routine care which may include tracing and counseling to return to the clinic.
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: E-NAV/CCT
Description: E-Nav is a stage 1 intervention to prevent lapses in HIV engagement. Trained e-peer navigators will develop rapport and provide support through phone calls and/or patient preferred social media platforms. They will meet once in person and then weekly electronically for 8 weeks, and then monthly. If an adolescent (1) misses an appointment >14 days, or (2) who have unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. CCT is a stage 2 intervention to treat lapses in HIV engagement by providing a small cash incentive for on-time clinic attendance and/or viral load suppression (following current MOH guidelines).
Study NCT04432571 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: E-Nav/IP-NAV
Description: E-Nav is a stage 1 intervention to prevent lapses in HIV engagement. Trained e-peer navigators will develop rapport and provide support through phone calls and/or patient preferred social media platforms. They will meet once in person and then weekly electronically for 8 weeks, and then monthly. If an adolescent (1) misses an appointment >14 days, or (2) has unsuppressed HIV RNA as per current MOH viral load threshold or (3) clinically documented non-adherence after >3 months of treatment he/she is re-randomized to a stage 2 intervention. IP-NAV is a stage 2 intervention to treat lapses in HIV engagement by providing in person navigation and counseling to a cash incentive for on-time clinic attendance and/or viral load suppression (MOH guidelines). Trained peer navigators will provide psychosocial support, case management, assess retention and adherence barriers in a systematic manner and work with the participant to develop social support and clear, feasible plans to address barriers
Study NCT05045105 — intervention group
Intervention type: OTHER
Intervention: Time necessary for ICP catheter placement by Intensive Care Physician vs Neurosurgeon following indication
Description: Time necessary for ICP catheter placement by Intensive Care Physician vs Neurosurgeon following indication and complications related to the maneuver between the two cohorts will be evaluated and compared.
Study NCT05407324 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dazucorilant 300 mg
Description: 300 mg of dazucorilant will be administered once daily in 4 softgel capsules of 75 mg dazucorilant/capsule.
Study NCT05407324 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dazucorilant 150 mg
Description: Dazucorilant and placebo will be administered once daily in 4 softgel capsules, 2 capsules with 75 mg dazucorilant/capsule and 2 capsules of placebo equivalent.
Study NCT05407324 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered once daily in 4 softgel capsules of placebo equivalent.
Study NCT05626439 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Staccato alprazolam
Description: Study participants will receive single dose of Staccato alprazolam by inhalation at pre-specified time points.
Study NCT05626439 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oral alprazolam
Description: Study participants will receive single dose of oral alprazolam at pre-specified time points.
Study NCT05321511 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Triptorelin acetate (a-GnRH)
Description: Adminsitration of triptoreline acetate 0.2 mg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.
Study NCT05321511 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ovitrelle® (hCG)
Description: Adminsitration of coriogonadotropine alfa 250 mcg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.
Study NCT05321511 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decapeptyl 0.1 mg® (a-GnRH) and Ovitrelle® (hCG) used together
Description: Adminsitration of triptoreline acetate 0.2 mg and coriogonadotropine alfa 250 mcg for final oocyte maturation in the second ovarian stimuation inthe Double stimulation protocol.
Study NCT04918498 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: early physiotherapy programs
Description: establishment of multidisciplinary teams, safety assessment, early activity physiotherapy and respiratory physiotherapy
Study NCT04918498 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: routine treatment
Description: provide routine nursing and rehabilitation program
Study NCT05173675 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empathy in Action for life with diabetes.
Description: In Phase 1 (Months 1-6) participants receive (Program):~1. Empathetic communications: A dedicated partner (lightly-trained lay person) who communicates with them via phone with timing and frequency defined by the participant within certain parameters. Two letters mailed during the 6 months that compile anonymized learnings from all participants in the callers panel of 10-20 participants, written as a newsletter to share back with the participant.~2. Material Incentives: One choice of health tool (weight scale or pedometer) selected with the caller in week 1 and expected to be received in weeks 3-5. Two small recognition gifts (valued at US$25) chosen by the caller based on their understanding of the participants preferences, and sent at month 2.5 and 4.5.~3. Educational Materials: Printed DM management educational materials mailed right after enrollment and randomization, and expected to be received in weeks 1-2.
Study NCT05173675 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Control Phase 2 Materials Only
Description: 1. Material Incentives:~   a. Choice of health tool (weight scale or pedometer) and 2 health promoting gifts chosen by the caller at the end of their 6 month measurement visit.~   i. Health tool is mailed out within the 7th month ii. Health promoting gifts are mailed out in the 8th and 10th month~2. Educational Materials a. The same educational materials mailed to participants in the intervention arm Program will be mailed to control arm participants after they complete their 6 months visit
Study NCT05837013 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Spinal anesthesia (with nerve block)
Description: Spinal Anesthesia and Nerve Block: No premedication will be applied. Spinal anesthesia will be administered to the patients in this group in the sitting position with a 27G Quincke needle (15 mg hyperbaric 0.5% bupivacaine) to be entered through the L2-L3 or L3-L4 interval. If hypotension develops, it will be corrected with a crystalloid infusion and ephedrine. These patients will be administered intravenous sedation with increasing doses of midazolam to provide adequate sedation. According to Hadzic, II and IH nerve block will be performed by applying 10 mL of 0.75% ropivacaine 2 cm above and 2 cm medial to the anterior superior iliac spine.
Study NCT05837013 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: General anesthesia (GA)
Description: General anesthesia: No premedication will be applied. In the waiting room, 10 mL/kg of Ringer's lactate solution will be infused IV in 30 minutes. In Group I, 2-2.5 mg/kg propofol and 1 μg/kg fentanyl IV will be given for induction; 0.6 mg/kg rocuronium will then be used to provide the muscle relaxation needed for intubation. After intubation, the tidal volume will be set to 6-8 mL/kg and the respiratory frequency PetCO2 32-36 mmHg in volume-controlled ventilation (VCV) mode. Anesthesia will continue to be provided with sevoflurane (1.5%-2%), oxygen-air mixture (FiO 2 = 0.4) and repeated doses of rocuronium (0.015 mg/kg). At the end of the surgery, neostigmine (2-2.5 mg) and atropine (1 mg) will be given IV to antagonize the residual neuromuscular block.
Study NCT05420870 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: exercise
Description: Six weeks of exercise intervention~To meet weekly 150 min of moderate to vigorous physical activity and twice weekly strength exercise General description of the exercise program~Main goal of the supervised exercise (1 hour per session, twice a week) are three folds. 1) Instruct participants to correctly perform prescribed exercises. 2) Encourage participants to be compliant to exercise program. 3) Participants were encouraged to hand in their exercise diary~Main goal of the home-based exercise is to perform calisthenics exercise daily. Participants were encouraged to perform at least one set of exercise (8-12 different exercises) and stretching (At least 3 days per week, but preferably most of the days) daily~Basic 8 exercises which increase ROM and strength of shoulder, lower back, Hip, Knee and ankle Additional 4 exercise to increase core strength and stability
Study NCT05941455 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Venus-Neo Surgical Aortic Valve
Description: Implant of a Venus-Neo Surgical Aortic Valve
Study NCT04468516 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: KKT
Description: Vibroacoustic sound waves applied focally.
Study NCT04468516 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: sham KKT
Description: sham KKT
Study NCT05553301 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Influenza mRNA Vaccine MRT5407
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular Injection
Study NCT05553301 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Recombinant Influenza Vaccine
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular Injection
Study NCT05553301 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza Standard Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular Injection
Study NCT05553301 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza High-Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular Injection
Study NCT05661851 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Investigational Lubricating Eye Drop in a Novelia® bottle
Description: Investigational Product
Study NCT05661851 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Blink® Tears eye Drops
Description: Control Product
Study NCT06103188 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The placebo pill will be given to the patients 1 hour prior to their planned surgery.
Study NCT06103188 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Diazepam
Description: Diazepam will be given to the patients 1 hour prior to their planned surgery.
Study NCT06103188 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melatonin
Description: Melatonin will be given to the patients 1 hour prior to their planned surgery.
Study NCT06343805 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AJ1-11095
Description: Type II JAK2 Inhibitor
Study NCT06040866 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise training
Description: Exercise training will be applied in the non-menstrual period during 2 menstrual cycles as stretching and relaxation exercises. Stretching exercises will include general stretching and specific stretching exercises and will take approximately 20 minutes in total. After the stretching exercises, relaxation exercise will be performed with diaphragmatic breathing for 10 minutes. The exercises will be performed with music accompanied by a physiotherapist once a week, and it will be recommended to do the exercises as a home program for 2 sessions a week.
Study NCT06040866 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise training
Description: Exercise training will be applied in the non-menstrual period during 2 menstrual cycles as stretching and relaxation exercises. Stretching exercises will include general stretching and specific stretching exercises and will take approximately 20 minutes in total. After the stretching exercises, relaxation exercise will be performed with diaphragmatic breathing for 10 minutes. The exercises will be performed with music accompanied by a physiotherapist once a week, and it will be recommended to do the exercises as a home program for 2 sessions a week.
Study NCT06040866 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pain neuroscience education
Description: Participants in the first research arm will be given pain neuroscience education once a week for 2 weeks after their first menstruation. The training will be repeated with a reminder session at the end of the 2nd menstruation.
Study NCT06040866 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Biomedical pain education
Description: Participants in the second research arm will be given biomedical pain education once a week for 2 weeks after their first menstruation. The training will be repeated with a reminder session at the end of the 2nd menstruation.
Study NCT05869903 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Orforglipron
Description: Administered orally.
Study NCT06407986 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: pulmonary function test
Description: Whether the estimated value of FEV1 and FVC is greater than 80%.
Study NCT05869903 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered orally.
Study NCT05083130 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: a wake prone positioning
Description: The team will give written and verbal advice and if necessary aid patients' positioning themselves in the prone position for at least 8 hours per day. The exact duration of prone sessions will be determined according to ward schedules to take account of nursing procedures, meal times and mitigation strategies. Other methods to encourage the maintenance of prone position includes phone calls to patients, carers or education of carers.
Study NCT05962580 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Isolated anterior cruciate ligament reconstruction with lateral extra articular tenodesis
Description: Anatomical single bundle ACLR with modified Lemiere technique
Study NCT05962580 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Isolated anterior cruciate ligament reconstruction only
Description: arthroscopic anatomical single bundle ACL Reconstruction
Study NCT06345989 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Alginate impression
Description: Alginate impression
Study NCT06345989 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Intraoral scan
Description: Intraoral scan with Trios 3Shape Scanner
Study NCT05231785 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ALN-APP
Description: ALN-APP will be administered intrathecally (IT)
Study NCT05231785 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered IT
Study NCT05006768 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Barcimiant
Description: 1 tablet contains 4 mg Barcitinib
Study NCT05006768 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olumiant (first dose)
Description: 1 tablet contains 4 mg Barcitinib
Study NCT05006768 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olumiant (second dose)
Description: 1 tablet contains 4 mg Barcitinib
Study NCT05509816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam
Description: Administered orally.
Study NCT05509816 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imlunestrant
Description: Administered orally.
Study NCT05913089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2450 injection + Chemotherapy
Description: TQB2450 injection is a humanized monoclonal antibody targeting programmed death ligand -1 (PD-L1).~Chemotherapy is a systematic treatment that kill fast growing cells.
Study NCT05913089 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB2450 injection + Anlotinib Hydrochloride Capsule
Description: TQB2450 injection is a humanized monoclonal antibody targeting programmed death ligand -1 (PD-L1).~Anlotinib hydrochloride is a muti-target tyrosine kinase inhibitor.
Study NCT05448183 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab, Gemcitabine,Oxaliplatin
Description: Toripalimab, 240mg, IV infusion, every 3 weeks (q3w), combined withTACE (Gemcitabine 1000mg/m2 , Oxaliplatin 135mg/m2) in a cycle of 3 weeks(q3w).
Study NCT05475132 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exergaming
Description: exercise games will be done for a total of 8 weeks ,100min of exergaming/week (5 days × 20 min).
Study NCT05475132 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Dexterity Exercises
Description: Exercises traditionally used for dexterity will be done for 8 weeks, 100min of exercises/week (5days × 20 min)
Study NCT04800354 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led Mindfulness Based Intervention
Description: Nurses will read patients a brief (1 minute) scripted, introduction to mindfulness and then have them listen to a very brief (1 minute 30 second) guided mindfulness practice validated in our prior research to encourage focused attention on breath and body sensations and open monitoring and acceptance of discursive thoughts, negative emotions, and pain. Finally, patients will be given an audio recording of the mindful pain management technique for use any time they experience intense pain or take pain medication before and after surgery.
Study NCT04800354 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nurse-led Pain Psychoeducation
Description: Nurses will provide psychoeducation about pain along with common pain coping strategies, such as rest, ice, and elevation, for use any time they experience intense pain or take pain medication before and after surgery.
Study NCT04800354 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Nurse-led Pain Psychoeducation
Description: Nurses will provide psychoeducation about pain along with common pain coping strategies, such as rest, ice, and elevation, for use any time they experience intense pain or take pain medication before and after surgery.
Study NCT05754931 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep neck flexors training + Conventional therapy
Description: Hold for 10 sec and repeated 10 times.Patients will be treated 3 times a week for 4 consecutive weeks
Study NCT05754931 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Muscles energy techniques + conventional therapy
Description: position of patient is in maximal comfort and lengthening After engaging the barrier use of an isometric contraction Feel the release and lengthen the muscle repeated for 4 time per session Patients will be treated 3 times a week for 4 consecutive weeks