AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06023290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Heart rhythm measurements with Preventicus®
Description: The sequence of the digital heart rhythm measurements is randomly assigned for each patient. The reference heart rhythm is determined by a simultaneous recording with a 12-lead ECG as gold standard.
Study NCT06023290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Heart rhythm measurements with FibriCheck®
Description: The sequence of the digital heart rhythm measurements is randomly assigned for each patient. The reference heart rhythm is determined by a simultaneous recording with a 12-lead ECG as gold standard.
Study NCT06023290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Heart rhythm measurements with Apple Watch®
Description: The sequence of the digital heart rhythm measurements is randomly assigned for each patient. The reference heart rhythm is determined by a simultaneous recording with a 12-lead ECG as gold standard.
Study NCT06023290 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Heart rhythm measurements with 6L Kardia Mobile®
Description: The sequence of the digital heart rhythm measurements is randomly assigned for each patient. The reference heart rhythm is determined by a simultaneous recording with a 12-lead ECG as gold standard.
Study NCT06322381 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Reinsertion achilles tendon
Description: Prone position, tourniquet over the thigh, direct midline incision, 2.0 cm proximal the insertion of the Achilles tendon up to 4.0 cm prolonged distal to the insertion is recommended. This is followed by a totally disinsertion of TA. At least a debridement of inflammatory or necrotic tissue as well as the removal of bony tissue is performed. tendon is re-inserted by 2-4 anchors.
Study NCT06322381 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Zadek osteotomy
Description: lateral position, under spinal anesthesia, tourniquet over the thigh, oblique lateral heel incision starting just anterior to the Achilles tendon, at a 45 angle to the long axis of the calcaneus posterior to the course of the sural nerve. A calcaneal osteotomy was then performed, two Kirschner wires, were then inserted from the posterior aspect of the calcaneus, over which cannulated screws were used for fixation of the osteotomy.
Study NCT05192187 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cross-sectional self-report (questionnaires)
Description: participants in this group will be ask to complete questionnaires on one occasion (i.e., cross-sectional investigation). The questionnaires will consist of a self-developed questionnaire and standard questionnaires. The main aspects of the self-developed questionnaires are~* perceived harmfulness of activities (selection of PHODA-SeV)~* cognitions about lifting and pain~* reasons for avoidance behaviour (lifting)~Standardised questionnaires include~* NRS for pain~* TSK-11~* FABQ~* RMDQ
Study NCT05162222 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Danicamtiv
Description: Specified dose on specified days
Study NCT05162222 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Specified dose on specified days
Study NCT05162222 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diltiazem
Description: Specified dose on specified days
Study NCT05150691 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: DB-1303/BNT323
Description: Administered IV
Study NCT05150691 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pertuzumab Injection
Description: Administered IV
Study NCT05150691 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ritonavir
Description: Administered oral
Study NCT05150691 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Itraconazole
Description: Administered oral
Study NCT05076422 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 3006337
Description: BI 3006337
Study NCT05076422 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT05806242 — intervention group
Intervention type: OTHER
Intervention: Italian Validation of the Italian Elderly Mobility Scale (EMS-I)
Description: Two physiotherapists independently evaluate the same enrolled patient with the Italian Elderly Mobility Scale (EMS-I) and Barthel Index
Study NCT04314687 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Umbilical Cord Mesenchymal Stem Cells
Description: The umbilical cord was removed from the donor and brought to cell culture facility immediately. Upon arrival, pre-sterility sample testing was performed to ensure the sample was free from contaminant. Culture processes were conducted in a laboratory room where high sterility and safety were guaranteed. Every batch of the cells was monitored by a series of quality control testing to assure the quality of the product.
Study NCT04314687 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Conditioned Medium
Description: Conditioned medium collected from umbilical cord mesenchymal stem cell (UC-MSC) cultured. Every batch of the conditioned medium was monitored by a series of quality control testing to assure the quality of the product.
Study NCT04314687 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Therapy
Description: Standard therapy for cerebral palsy such as physiotherapy
Study NCT05675709 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Training and Education
Description: Undergo group trainings
Study NCT05934188 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Microbiome analyses
Description: The Microbiome analyses will be derived from a stool sample (16S rRNA sequencing targeted metagenomic analyses).
Study NCT05934188 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Inflammatory markers
Description: Inflammatory markers will be evaluated in terms RNA expression level in plasma blood sample.
Study NCT05934188 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Alzheimer's Disease biomarkers
Description: The Alzheimer's Disease biomarkers will be measured in the plasma of prodromal Alzheimer's Disease patients.
Study NCT06484205 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: WHO QualityRights e-training
Description: WHO QualityRights training provides the necessary skills to support people with psychosocial disabilities in advocating for their rights. The QualityRights online course includes six main modules: 1) Human Rights; 2) Human rights, mental health and disability; 3) Legal capacity and the right to decide; 4) Stop coercion, violence and mistreatment; 5) Quality services and inclusion in the community; 6) Mental health, well-being and recovery and it will take approximately 8 hours for completion. QualityRights course modules can be completed at each participant's pace and needs. The training is considered concluded once the quizzes provided at the end of each of the six modules have been successfully completed and upon completion of the course it will be possible to download your official WHO certificate from the QR platform.
Study NCT06484205 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Emotional intelligence e-training
Description: This course offers caregivers resources and knowledge so that they are able to manage their emotions and gain quality in the care they provide to others and in their own lives. The course duration is similar to that of the QualityRights online course and is intended for caregivers of people with disabilities and others interested
Study NCT06522984 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tranexamic acid injection
Description: to evaluate and compare efficacy of:~* Fractional Er: YAG laser combined with topical hydroquinone.~* Intradermal injection of tranexamic acid combined with topical hydroquinone cream.~* Oral administration of tranexamic acid combined with topical hydroquinone cream. In treating refractory melasma.
Study NCT06187038 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic exercises
Description: The therapeutic exercise program will include warm-up, resistance, neuromuscular, mobility, and balance exercises. Over ten weeks, two sessions of the therapeutic exercise program will be carried out individually, lasting approximately 60 minutes each-a total of 20 therapeutic exercise sessions. Therapeutic exercise sessions will be carried out at least 24 hours between sessions. Therapeutic exercises will be performed in up to three sets of 8-12 repetitions or 30-60 seconds each, with rest intervals of 90 seconds between sets.
Study NCT06187038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic exercises
Description: The therapeutic exercise program will include warm-up, resistance, neuromuscular, mobility, and balance exercises. Over ten weeks, two sessions of the therapeutic exercise program will be carried out individually, lasting approximately 60 minutes each-a total of 20 therapeutic exercise sessions. Therapeutic exercise sessions will be carried out at least 24 hours between sessions. Therapeutic exercises will be performed in up to three sets of 8-12 repetitions or 30-60 seconds each, with rest intervals of 90 seconds between sets.
Study NCT05168930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: C4-15
Study NCT06187038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic exercises + pain neuroscience education program
Description: In addition to the therapeutic exercise protocol previously reported in the control group, research participants allocated to the experimental group will undergo an education program in the neurosciences of chronic pain carried out one day a week between the two therapeutic exercise sessions lasting ten weeks.~The chronic pain neuroscience education program will be based on three domains. Making sense of pain, Exposure with control, and Lifestyle changes also urge modifications aimed at improving sleep, stress, and anxiety.
Study NCT06275932 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interventional group
Description: Newborns will be covered with a thermal blanket during skin-to-skin contact in delivery room.
Study NCT06275932 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care group
Description: Newborns will be covered with a bed wetting mat and cotton sheet during skin-to-skin contact in delivery room.
Study NCT05168930 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanubrutinib
Description: C1-15
Study NCT06282692 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: INAVAC (Vaksin Merah Putih - UA-SARS CoV-2 (Vero Cell Inactivated) 5 µg
Description: Dose : 1 dose 0.5 ml containing 5 µg inactivated SARS-CoV-2 virus, Tween 80, histidine, Polysorbate 80, Aluminium hydroxide gel, and sodium chloride.
Study NCT05045066 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Cholecalciferol
Description: Given PO
Study NCT05045066 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Ancillary studies
Study NCT05045066 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT05650554 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Quadrivalent Influenza mRNA Vaccine MRT5413
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular injection
Study NCT05650554 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Recombinant Influenza Vaccine
Description: Pharmaceutical Form: Liquid frozen solution in a vial~Route of Administration: Intramuscular injection
Study NCT05650554 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza Standard Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular injection
Study NCT05650554 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Quadrivalent Influenza High-Dose Vaccine
Description: Pharmaceutical Form: Liquid suspension for injection in pre-filled syringe~Route of Administration: Intramuscular injection
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Near logMAR letter acuity
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Near LogMAR word acuity
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Red Green Stereoacuity
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Auckland Optotype/Auckland Vanishing Optotypes
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Vanishing Optotype Sloan Letters
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Letter Contrast Sensitivity
Description: Comparison of gold standard printed tests and computerised versions
Study NCT06224751 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Low Contrast Letter Acuity
Description: Comparison of gold standard printed tests and computerised versions
Study NCT05313217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Knee extension angle
Description: Knee Extension Angle (KEA):~* This test will be administered with an ankle-foot orthosis (AFO) maintaining the participants ankle in neutral.~* The participant will lie supine on the examination table with the contralateral lower extremity (LE) stabilized on the support surface using a mobilization strap.~* The hip of the lower being examined will be flexed to 90 degrees.~* The participant will then actively straighten their lower leg while maintaining upper leg in same position~* Once the participant feels they are at maximal knee extension (patient instructed to straighten leg as far as what is comfortable), the angle will be measured with iPhone Inclinometer.~* Participant asked to report any symptoms they are feeling and where (recorded for qualitative analysis)
Study NCT05313217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Straight Leg Raise
Description: Straight Leg Raise (SLR):~* Position the participant in supine on the plinth with knees extended and L LE strapped to the plinth~* The participant will keep the AFO donned on the R distal ankle to keep the ankle in neutral position.~* A researcher will passively lift the participant's right leg moving at a slow but consistent pace of approximately 15 degrees per second, while keeping it straight until a significant resistance is detected or the participant reports a production of symptoms, whichever occurs first.~* Measurement of the SLR angle will be assessed with iPhone inclinometer.~* Participant asked to report any symptoms they are feeling and where (recorded for qualitative analysis)
Study NCT05313217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Slump Test
Description: Slump Test Procedure:~* Participant will be instructed to sit upright with their legs over the edge of table~* AFO remains on R leg~* Participant will sequentially flex trunk, look down at the floor~* Participant will extend R knee until symptoms are felt. Measure of angle with iPhone inclinometer placed at superior aspect of medial malleolus~* Participant asked to report any symptoms they are feeling and where (recorded for qualitative analysis)
Study NCT05313217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Extended slump test
Description: Extended Slump Procedure:~* Participant will be instructed to sit upright with their legs over the edge of table~* AFO remains on R leg~* Participant is asked to arch their lower back into maximal extension in sitting, stabilized to research bench to maintain hyper-lordosis posture.~* The participant is asked first flex cervical spine, then to extend their knee until it reaches full ROM or symptoms are felt that limit ROM.~* Knee extension ROM is assessed with iPhone inclinometer at superior aspect of medial malleolus.~* Participant asked to report any symptoms they are feeling and where (recorded for qualitative analysis)
Study NCT04811794 — intervention group
Intervention type: OTHER
Intervention: Physical examination, diagnostic tests, laboratory tests
Description: Physical examination, diagnostic tests (e.g. lung function test, echocardiography, audiometry), and laboratory tests (e.g. kidney parameter, hormonal levels) depend on examined organ system.
Study NCT04811794 — intervention group
Intervention type: OTHER
Intervention: Personal history
Description: Personal history on diagnosis, treatment, and socioeconomic factors
Study NCT04215510 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: endonasal endoscopic surgery
Description: 143 patients will undergo endonasal endoscopic surgery
Study NCT04215510 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: radiation therapy(IMRT)
Description: 143 patients will undergo radiation therapy.
Study NCT04887818 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 2% Diltiazem ointment with 1.5% lidocaine
Description: 3 g of topical 2% diltiazem ointment with 1.5 % lidocaine applied in the perianal region circumferential q12h x 12 weeks
Study NCT04887818 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 0.3% Nifedipine ointment with 1.5% lidocaine
Description: 3 g of topical 0.3% nifedipine ointment with 1.5 % lidocaine applied in the perianal region circumferential q12h x 12 weeks
Study NCT04489589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midodrine
Description: 10mg PO/NG q8h
Study NCT04489589 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 10mg PO/NG q8h
Study NCT06424379 — intervention group
Intervention type: OTHER
Intervention: Histopathological analysis
Description: Morphological analysis will include the description of architectural patterns and cytological features on formalin-fixed and paraffin-embedded (FFPE) tissue samples retrieved from the routine diagnostic archives of the Pathology Department of the University Hospital Lyon Sud.~A panel of immunohistochemical staining will be analyzed including CD20, CD3, CD10, Bcl-6, Bcl-2, CD5, CD23, CD38, MUM1, Ig kappa, Ig lambda, MEF2B, LMO2, MNDA, IRTA1, P53, CMYC and Ki67 . /MIB1. Diffuse large B-cells lymphomas will be classified into two distinct subgroups: centro-germinative (GC) and non-centro-germinative (nGC), using the Hans algorithm.
Study NCT06424379 — intervention group
Intervention type: GENETIC
Intervention: Molecular analysis
Description: Next-generation sequencing (NGS) analysis will be performed on FFPE tissue samples retrieved from the routine diagnostic archives of the Pathology Department of the University Hospital Lyon Sud. A panel of 73 genes dedicated to lymphoma diagnosis determined by a consensus of French Lysa experts will be used. The identification of genetic variants will be followed by the attribution of pathogenicity class in accordance with the guidelines for validation of NGS-based oncology panels.~RNA extraction will classify DLBCLs into two distinct subgroups: germinal-centre B-cell-like (GCB-DLBCL) and activated B-cell-like (ABC-DLBCL).
Study NCT05348889 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 1A46 Injection
Description: Participants will receive IV 1A46 weekly for Cycles 1-8, then every 3 weeks (Q3W) for Cycles 9-16 (21 days/cycle).
Study NCT01393587 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Taking blood samples
Study NCT05793567 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Coronary angiogram with coronary reactivity testing (CRT)
Description: CRT is an angiography procedure (using X-ray) to examine the small blood vessels in the heart and how they respond to three drugs (adenosine, acetylcholine and nitroglycerin) as per clinical protocol.
Study NCT05293288 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EEG-guided general anesthesia
Description: pEEG monitoring will start with the beginning of induction of general anesthesia and will end with the end of surgery (surgical suture). In the EEG-guided group, depth of anesthesia will be adjusted to target PSI values between 25 and 50 and spectral edge frequency between 10 and 15. In case of contradictory values, the raw EEG waveforms, ARTF, EMG, as well as the overall clinical situation will be evaluated for decision making.
Study NCT05700214 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ropivacaine injection
Description: 30ml of 0.375% ropivacaine
Study NCT05700214 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine IV
Description: Before induction bolus of 1% lidocaine 1,5mg/kg IBW i.v., continuous infusion of 1% lidocaine intraoperatively rate 1 mg/kg IBW i.v.
Study NCT05297916 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: enteral feeding
Description: to intake oral feeding or delay it
Study NCT06429358 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Lactobacillus rhamnosus
Description: The probiotic supplement was delivered in the form of easy-to-swallow capsules.
Study NCT06429358 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control Group
Description: Participants in the control group were given a placebo that looked, tasted, and felt just like the probiotic pill.
Study NCT05249634 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jatenzo Pill
Description: oral tablet daily
Study NCT04829981 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SAFEWATER systems for drinking water disinfection
Description: A domestic water purification technology, consisting of a raw water storage tank, a pump, a filtration unit (2 cartridge filters), a UVC disinfection unit (UV lamp), a storage tank for drinking water (treated and safe water), and a distribution network inside the house for drinking water.