AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06164314 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Dexmedetomidine
Description: In Dex group, dexmedetomidine will continue to be used during and after surgery, with a infusion of 0.4ug/kg/ h from anesthesia induction to dural closure, and then 0.08ug/kg/ h to 48 hours postoperatively.In placebo group, equivalent normal saline will be injected during operation, and the intravenous analgesia pump will not contain dexmedetomidine after operation
Study NCT04858542 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Educational Vocal Health Modules
Description: We have developed four educational health modules (total duration of approximately 30 minutes). First, these modules explain how masks impact communication and voice, then they describe health strategies to improve communication and voice, and finally, they give real-life examples of how the strategies can be implemented into the work setting.
Study NCT04669028 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NE3107
Description: NE3107 is an investigational orally bioavailable, blood-brain barrier permeable anti-inflammatory agent with a new mechanism of action targeting multiple mechanisms of pathology in Alzheimer's disease.
Study NCT04669028 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: capsules that do not contain NE3107
Study NCT05512858 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: sensory room
Description: the room has dimmed lighting, sensing games, essential oils, picture books and cookbooks, two heavy blankets (weighing 9 kg and 11 kg), a rocking chair, and a vestibular plate. The occupational therapist will accompany the first entry into the room to create a sensory profile, adjust and instruct on the means, and write a treatment card. The treatment card will record the patient's choices and instructions for arranging the room, and it will be used by the staff members who will admit the patient as needed. Each patient will be able to stay in the room for self-treatment according to the individual treatment card prepared at the first sensory room treatment, up to half an hour.
Study NCT04834908 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Equine COVID-19 Antiserum
Description: Equine COVID-19 antiserum is a polyclonal antibody and it contains Equine COVID-19 immune globulin G.
Study NCT04834908 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard of care
Description: Standard of care for COVID 19 infection based on the current guidelines and institutional practice will be provided
Study NCT04834908 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard of care
Description: Standard of care for COVID 19 infection based on the current guidelines and institutional practice will be provided
Study NCT05296317 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dense dose epirubicin-cyclophosphamide chemotherapy and G-CSF (filgrastim, lenograstim)
Description: - Arm 1: 2 cycles of chemotherapy with administration of G-CSF (filgrastim or lenograstim) on D2, D4 to D7 or D8..~Realization of blood sampling at D1, D4, D8 and D14
Study NCT05296317 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dense dose epirubicin-cyclophosphamide chemotherapy with administration of peg-G-CSF (pegfilgrastim)
Description: - Arm 2: 2 cycles of chemotherapy with administration of peg-G-CSF (pegfilgrastim) on D2.~Realization of blood sampling at D1, D4, D8 and D14
Study NCT06199804 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Toy Hygiene Training
Description: The training was given to the mothers in 2 sessions (morning and afternoon), each lasting approximately 30 minutes, accompanied by the Toy Hygiene Guide. The sessions were presented face to face in the mother's room in the form of explaining, showing, question and answer and power point, at a time convenient for the mother and the child, outside the morning and afternoon treatment and care hours. After the first session was completed, an appointment was made with the mother for the afternoon session. In the second session, the information in the book that was not given in the first session was presented to the mothers face to face in the mother's room, outside the treatment and care hours, at a time convenient for the mother and the child. After the training was completed, a final five-minute discussion was held with the mothers in the form of a general question and answer session. The training book was given to the mothers in the experimental group on the first day.
Study NCT06302803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intermittent fasting plus time-restricted eating
Description: Participants in the mTRE group will be instructed to eat during a window of 8 h (8 am to 4 pm) 5 days and fast (approximately 500-600 kcal per day) 2 days per week.
Study NCT06302803 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Calorie restriction
Description: Participants will follow receive a diet of 1500-1800kcal/d for men and 1200-1500kcal/d for women, without restriction on eating time.
Study NCT04755764 — intervention group
Intervention type: DRUG
Intervention: Labetalol
Description: Beta blocker
Study NCT04755764 — intervention group
Intervention type: DRUG
Intervention: Atenolol
Description: Beta blocker
Study NCT04755764 — intervention group
Intervention type: DRUG
Intervention: Nifedipine
Description: Calcium channel blocker
Study NCT06266559 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chang Geng Healthy Drink
Description: Chang Geng Healthy Drink consists of Zingiberis Rhizoma, Codonopsis pilosula, Atractylodis Macrocephalae Rhizoma, Poria cocos, Citri reticulatae Pericarpium
Study NCT06357845 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Survey
Description: Participants will complete a brief web-based survey asking about their experiences related to the February 3, 2023 train derailment, health experiences and concerns following the derailment, and background information regarding their health history. The survey will last approximately 15 minutes.
Study NCT06357845 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Biological specimen collection
Description: Participants may possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings. Participants will be asked which samples they are interested in providing. Participants will receive a specific sample collection kit based on their selection. For blood samples, participants will receive a mailed collection kit at their mailing address. A member of the research team will reach out to schedule blood sample collection, which may take place at home with a trained phlebotomist or at a designated collection site. A total of 1-2 teaspoons of blood (5-10 milliliters) will be collected at a one-time blood draw. For either saliva, hair, and/or toenail clippings, participants will be sent a sample collection kit and receive instructions at their mailing address. This kit also includes a return mailing envelope. Participants will provide the selected samples in the collection kits, place them in the return mailing envelope, and send them back to the research team.
Study NCT06357845 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Communications about study updates and future research opportunities
Description: By consenting to participate in this study, the research team will send updates about the research results and any additional study opportunities to participants.
Study NCT06357845 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Qualitative interview
Description: A total of 40 study participants will be recruited to participate in a 90-minute interview with open-ended questions. The interviews will be video and audio-recorded.
Study NCT04651205 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: vitamin B1 and magnesium supplements
Description: vitamin B1 - 100 mg/day magnesium - 400 mg/day
Study NCT05362357 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: iSTART Web-app
Description: 30-day substance prevention web-app for students at a Hispanic Serving Institution.
Study NCT05362357 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iSTART Web-app
Description: 30-day substance prevention web-app for students at a Hispanic Serving Institution.
Study NCT04408677 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Zilia Ocular
Description: Measurement of the oxygen saturation in the eye fundus
Study NCT04824703 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxygen
Description: * Decreasing fraction of inspired oxygen and its effect on mortality and myocardial function~* administered by invasive mechanical ventilation with fraction of inspired oxygen between 0.21 and 1
Study NCT04824703 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Oxygen
Description: * Decreasing fraction of inspired oxygen and its effect on mortality and myocardial function~* administered by invasive mechanical ventilation with fraction of inspired oxygen between 0.21 and 1
Study NCT04861311 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness/Acceptance-Based Smartphone App (MABSA) Intervention
Description: The intervention is based on the principles of Acceptance and Commitment Therapy (ACT). Therefore, the intervention is an ACT-based smartphone app delivered for 6 weeks in which participants will be applying the mindfulness and acceptance exercises embedded in the app. The mindfulness and acceptance exercises are audio-guided mindfulness meditations and video lessons about ACT.
Study NCT04766151 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Transdermal glyceryl trinitrate 10mg patches
Description: Transdermal patches applied to skin 30 minutes before cardiac catheterization
Study NCT04766151 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo patches
Description: Transdermal placebo patches applied to skin 30 minutes before cardiac catheterization
Study NCT04990375 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: tDCS
Description: 5 sessions of 20-minute tDCS at 2 mA over the dorsolateral prefrontal cortex (35cm² sponge)
Study NCT04990375 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: tDCS
Description: 5 sessions of 20-minute tDCS at 2 mA over the dorsolateral prefrontal cortex (35cm² sponge)
Study NCT06028425 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LOXO-783
Description: Administered orally.
Study NCT06287372 — intervention group
Intervention type: OTHER
Intervention: Cardioplegic solution
Description: Patients were randomly assigned to undergo surgery using one of two methods for myocardial protection
Study NCT05572346 — intervention group
Intervention type: OTHER
Intervention: Home-based telerehabilitation program delivered through digital devices
Description: To evaluate the effects of digital home-based telerehabilitation program on functional and spirometric measures as well as on quality of life in patients with chronic respiratory disease
Study NCT04902898 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Circumcision in adults using sterile single-use circular stapling device
Description: Circumcision in adults using sterile single-use circular stapling device CIRCCURER II (Jiangxi Langhe Medical Instrument Co., Ltd., Guangzhou, China)
Study NCT04783974 — intervention group
Intervention type: DEVICE
Intervention: Dental implants
Description: Treatment of total or partial edentulism through the placement of osseointegrated dental implants
Study NCT04902898 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Circumcision in adults
Description: Circumcision in adults
Study NCT01003405 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KUC-7483
Study NCT06186583 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pimicotinib（ABSK021）
Description: A standard meal should be given to the subjects in the evening before dosing. Then, the subjects should fast for at least 10 hours. Water is not prohibited overnight. The next morning, the subjects should administer study drug in fasted state with warm water. The total volume of warm water and suspension is approximately 240 mL. Water is prohibited from 1 hour before dosing to 1 hour after dosing. No food is allowed within 4 hours after dosing. During the study, subjects will receive standardized meals at approximately the same time each day.
Study NCT04074226 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector Spinae Plane block
Description: The Erector Spinae Plane (ESP) block is a new block first described in 2016 which blocks terminal branches of the lower thoracic and lumbar nerve roots. It is performed by injection of local anesthetic in the fascial plane below the erector spinae muscle group.
Study NCT04074226 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus Lumborum Block
Description: Ultrasound-guided QL block has been reported to provide effective analgesia in patients undergoing lower abdominal surgical procedures, including in patients undergoing abdominal hysterectomy. Ultrasound guidance offers a number of advantages, including the ability to visualize the anatomy, perform real-time navigation, and direct observation of local anesthetic spread. The QL block is performed via ultrasound-guided injection of local anesthetic in the fascial planes above or below the QL muscle
Study NCT05600829 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: BWLT+CR
Description: Patients will attend twelve 2-hour group-based weekly sessions (over Zoom) in addition to their twice-weekly CR exercise sessions, followed by biweekly follow-up sessions alternating between individual phone-based sessions with a facilitator, and group-based sessions for an additional 12 weeks. The empirically validated ASPIRE BWLT was recently adapted for an AF population with obesity. Briefly, the BWLT was modified to incorporate education and practical strategies requested by patients, including AF risk factor management, pathophysiology, medications, and disease course; exercising with AF; and coping with difficult emotions regarding AF. Weekly treatment goals focus on nutrition and moderate calorie reduction while emphasizing adherence to an individualized CR exercise prescription. The BWLT program will be delivered by senior clinical psychology PhD students and supervised by a registered Clinical Health Psychologist.
Study NCT05600829 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: CR-Only
Description: The CR program consists of education, medication management, risk factor modification and 12 weeks of twice-weekly supervised cardiovascular exercise sessions. Patients with AF undergo a symptom-limited graded exercise stress test at intake, 12-weeks, 24-weeks, and 1-year post-randomization, where cardiorespiratory fitness (i.e., peak metabolic equivalents \[METS\]) and cardiometabolic risk factors (blood pressure, blood lipid profile, BMI, waist circumference, depression and anxiety symptoms, tobacco use, and exercise volume) are assessed.
Study NCT06209294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK104
Description: AK104(10 mg/kg) d1,22
Study NCT06209294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: AUC=2 d1,8,15,22, 29, 36
Study NCT06209294 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: 125mg／m2 d1,8,15,22,29,36
Study NCT06172816 — intervention group
Intervention type: OTHER
Intervention: SARS-CoV-2
Description: a virus infection
Study NCT05325229 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel for injection (Albumin-bound)
Description: Docetaxel for injection (Albumin-bound), by intravenous infusion，75 mg/m\^2 or 100 mg/m\^2 once every 3 weeks.
Study NCT05325229 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab, by intravenous infusion, 15 mg/kg once every 3 weeks.
Study NCT04680624 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Fecal sample collection
Description: During the study, patients will be ask to collect fecal samples using sample collection kits. A total of 4 stool samples per patient will be collected.
Study NCT04603469 — intervention group
Intervention type: OTHER
Intervention: Non invasive blood pressure
Description: measurement of blood pressure during induction of general anesthesia
Study NCT05077618 — intervention group
Intervention type: OTHER
Intervention: sampling of dental plaque and blood sample during the treatment
Description: sampling of dental plaque and blood sample analysed on day 1
Study NCT05351424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audiovisual Intervention- Radiation Therapy Education
Description: A video with educational information will be shown regarding radiation therapy.
Study NCT05351424 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ASTRO Radiation Therapy for Breast or Prostate Cancer Brochure
Description: Brochure with written information will be given to the subject regarding radiation therapy.
Study NCT05351424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Audiovisual Intervention- Cancer Clinical Trials Education
Description: A video with educational information will be shown regarding cancer clinical trials.
Study NCT05351424 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: NCI Taking Part in Cancer Research Studies Brochure
Description: Brochure with written information will be given to the subject regarding cancer clinical trials.
Study NCT04056624 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: High carotenoid juice
Description: Juice with high carotenoids
Study NCT04056624 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo control - Apple juice
Description: Juice with negligible carotenoids
Study NCT04771780 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KHK7791
Description: oral administration
Study NCT05441540 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Internal Jugular Vein Compression Collar
Description: The current FDA approved internal jugular vein compression collar, marketed as the Q collar, is manufactured by Q30 Innovations Home. It is designed to be worn around the neck of individuals aged 13 and older. It functions by lightly compressing the internal jugular vein's bilaterally, safely increasing intracranial volume and intracranial pressure. The FDA approved neck collar device is made of a thermoplastic elastomer that is specifically fitted to an individual to provide mild internal jugular vein compression. The product was developed and confirmed with ultrasonography to confirm appropriate fit and compression of the vein based on an athlete's neck circumference.
Study NCT05399108 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ultrasound Guided Lateral Approach Catheterization of Jugular Internal Vein
Description: The jugular internal vein is displayed on its short axis. On the image are displayed the trapezius muscle and layers of skin. Just above the trapezius muscle using the in-plane technique is done puncture of the vein. By Seldinger's technique, catheterization is done. The whole procedure is done according to the newest international recommendations for central vein catheterization.
Study NCT05399108 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrasound Guided Conventional Approach Catheterization of Jugular Internal Vein
Description: The jugular internal vein is displayed on its short axis. The cannulation is done by the conventional approach (middle approach - the most frequently used).
Study NCT06168825 — intervention group
Intervention type: OTHER
Intervention: Mind Over Matter (MOM)
Description: Each participant's involvement in the study will include:~* Attending a Pre-Program Orientation which will be held a week before the first MOM Session.~* Completing 5 weekly sessions of MOM~* Completing 2 surveys; one will be given before the start of the intervention (a pre-test) and the other will be given after the last MOM Session (a post-test)~Participants will also have the option to participate in an optional Focus Group session which will occur a week after the last MOM Session ends~Participants will spend about 6 weeks in this study. If they decide to participate in the optional session, they will spend about 7 weeks in this study.~Please note, this entire Intervention will be offered online. There will be no in-person sessions or visits.
Study NCT05016804 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: AlloRx
Description: cultured allogeneic adult umbilical cord derived mesenchymal stem cells
Study NCT05666440 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Visco-Circumferential-Suture-Trabeculotomy in Primary Open Angle Glaucoma.
Description: A superior limbal-based conjunctival flap and a paracentesis. A superficial rectangular scleral flap 4×4 mm was fashioned and dissected forward toward the limbus. A deep sceral flap (2×2 mm) was then created toward the limbus underneath the superficial flap exposing the scleral spur and deroofing SC. Viscoelastic (Healon GV, Pfizer, NY) was injected (using a standard 30 G viscocanalostomy cannula) into the ostia of SC Then, the 5/0 polypropylene suture tip was cauterized into a blunt tip (to ensure atraumatic probing of SC). The tip was inserted into the left ostium of SC using a microsurgical forceps and advanced through the whole circumference of the canal. When the tip presented to the right ostium the AC was filled with a viscoelastic through the paracentesis and traction was applied to approximate both ends of the 5/0 polypropylene suture, thus creating a visco-360-degree trabeculotomy.
Study NCT05666440 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
Description: A fornixbased conjunctival incision followed by creation of a partial thickness (about 50% thickness) triangular (4×4×4 mm) scleral fap, followed by localization of Schlemm's canal by radial incisions straddling the limbus. High viscosity sodium hyaluronate (Healon GV, Pfzer) was then slowly injected into both ends of Schlemm's canal. Trabeculotomy was completed using the standard Harm's trabeculotome (Geuder Instruments), the scleral fap was then secured tightly with interrupted 10/0 Nylon sutures and conjunctival closure ensued.
Study NCT00818246 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham light