AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05951348 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Delayed cord clamping for 30 seconds
Description: waiting for 30 seconds after delivery of the fetus or milking of the cord in the direction of the fetus 10 times in time frame 10-15 seconds
Study NCT06053242 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CELZ-201-DDT
Description: Subjects enrolled in the trial will receive CELZ-201-DDT at the specified dose into the lumbar paraspinal musculature. Each subject will receive a total of six injections, three injections on each side, under direct ultrasound guidance.
Study NCT05665959 — intervention group
Intervention type: OTHER
Intervention: Reiki
Description: Reiki is based on the belief that disease occurs when an energy center is blocked, and that the energy is transmitted through touch. In distant Reiki, Reiki practitioners followed the traditional Usui Reiki protocol for distant healing.
Study NCT06053242 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subjects will receive a placbeo injection into the lumbar paraspinal musculature. Each subject will receive a total of six injections, three injections on each side, under direct ultrasound guidance.
Study NCT05572294 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness meditation, breathing exercises (including incentive spirometry), and yoga therapy
Description: Sickle cell patients admitted with a vaso-occlusive pain crisis over a consecutive 12-week period will be offered participation in the study. After providing informed consent, participants will have access to 4 videos containing guided mindfulness meditation, breathing exercises, and gentle yoga therapy. The videos are 5-12 minutes long and taught by a physical therapist who is also certified in yoga therapy. Participants may turn off the video at any time. Participants will have access to the videos for the duration of their hospitalization, and they may watch the videos as many times as they desire.
Study NCT05518916 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nonfarmacology method
Description: Yakson Method and Swaddling
Study NCT06562985 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3018250 Dose 1
Description: Infusion, single dose
Study NCT05647044 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: intermittent theta burst stimulation
Description: intermittent theta burst stimulation (iTBS) will be delivered with the Magventure MagProX100 with MagOption stimulation and Magpro Cool Coil B65 A/P. The Magpro Cool Coil B65 A/P can be switched to active or placebo. The Magventure C-B60 coil will be used to deliver single TMS pulses for motor threshold determination.
Study NCT06562985 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: BAY3018250 matching placebo, infusion
Study NCT06562985 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: BAY3018250 matching placebo, injection
Study NCT06562985 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3018250 Dose 2 infusion
Description: Infusion, single dose
Study NCT06562985 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BAY3018250 Dose 2 injection
Description: Injection, single dose
Study NCT05862636 — intervention group
Intervention type: BEHAVIORAL
Intervention: Mindfulness Training
Description: All participants will follow a mindfulness course consisting of group sessions of 2-3h duration that are organized (nearly) weekly and are spread over a period of eight weeks. The specific timeline and organisation of the course may differ between the participating sites but all courses will involve a comparable amount of contact hours with the mindfulness trainer. Each session consists of guided experiential mindfulness exercises (e.g., body scan, breathing space, breath focus, walk meditation), sharing of experiences of these exercises, reflections in small groups, psychoeducation, and review of home practices.~The mindfulness courses are based on one of the two most well-known MBIs, Mindfulness-Based Cognitive Therapy (Segal et al., 2002) and Mindfulness-Based Stress Reduction (Kabat-Zinn, 1990), or a combination thereof. Courses follow a standardised protocol with group sessions and daily homework tasks taught by experienced and certified mindfulness trainers.
Study NCT05162729 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Game-like online working memory training
Description: Participants in the WM group will be receiving two types of WM training tasks (two mini-games) in each session. Half of the training time will be spent on playing a game that requires visual-spatial WM, and the other half of the training time will be spent on playing a game that demands verbal WM. In both the games, the participant is asked to remember the pictures or audios (numbers) presented, and then recall them and select them on the screen.
Study NCT05162729 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Game-like online social emotional training
Description: Participants in the SE group will be also receiving two types of SE training tasks in each session, to match with the ones in the WM training. There are two mini-games for training.~To match with the spatial-visual WM training, participants in the SE group will be asked to first look at a picture that depicts a daily social scenario (i.e., a child who fell down and hurt himself), and then to choose an emotion that the child in the picture may feel from four options of facial emotions displayed on the screen. The other mini-game, with the aim to match with the auditory WM training, will first tell a short story of a social scenario (i.e. David accidentally fell down and got hurt), and then will ask the child to choose the emotion that the character in the story may feel from the four options displayed on the screen. Each mini game lasts for about 7 minutes in each training session.
Study NCT05082324 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Adapted physical activity
Description: Patient participates in an adapted physical activity program for 3 months, with 2 one-hour sports sessions per week
Study NCT05664217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-255 at 1.5 µg/kg
Description: NKTR-255 at 1.5 µg/kg
Study NCT05664217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-255 at 3.0 μg/kg
Description: NKTR-255 at 3.0 μg/kg
Study NCT05664217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NKTR-255 at 3.0/6.0 μg/kg
Description: NKTR-255 at 3.0/6.0 μg/kg
Study NCT05664217 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Comparator
Description: Commercially available 0.9% Sodium Chloride Solution for Injection (USP)
Study NCT05647044 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: placebo intermittent theta burst stimulation
Description: intermittent theta burst stimulation (iTBS) will be delivered with the Magventure MagProX100 with MagOption stimulation and Magpro Cool Coil B65 A/P. The Magpro Cool Coil B65 A/P can be switched to active or placebo. The Magventure C-B60 coil will be used to deliver single TMS pulses for motor threshold determination.
Study NCT04729582 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Primary human muscle stem cells (Satori-01)
Description: Primary human muscle stem cells are isolated from patient's muscle tissue and expanded ex-vivo. They are injected into the urethral sphincter region as a one-time autologous treatment.
Study NCT04729582 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo is the injection solution without muscle stem cells.
Study NCT04937816 — intervention group
Intervention type: DRUG
Intervention: Placebo
Description: Placebo
Study NCT04937816 — intervention group
Intervention type: DRUG
Intervention: Empagliflozin
Description: Empagliflozin once daily
Study NCT06203834 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: I-Fiber Pearl
Description: Eat 200g for once, and once a day.
Study NCT05987072 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sisunatovir
Description: Will be given as a single dose on Day 1 in a fasted state followed by repeated twice daily doses (200 mg BID, Q12 hours) from Days 4-7 plus 1 morning dose on Day 8 in a fed state
Study NCT05339243 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ES 1
Description: Two capsules orally once daily after breakfast for 84 days
Study NCT05339243 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: HT ES1
Description: Two capsules orally once daily after breakfast for 84 days
Study NCT05339243 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Two capsules orally once daily after breakfast for 84 days
Study NCT06203834 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Eat 200g for once, and once a day.
Study NCT06323915 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: intraocular lens implantation in cataract surgery
Description: Implantation of intra ocular lenses in both patient's eyes in remplacement of the natural cataracted cristallin that has been removed from the patient's eye during the cataract surgery
Study NCT06291116 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: standard care + rotigotine at 4 mg/24h for 24 months.
Description: standard care + rotigotine at 4 mg/24h for 24 months.
Study NCT06291116 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: standard care for 24 months.
Description: standard care for 24 months.
Study NCT06312943 — intervention group
Intervention type: OTHER
Intervention: Collection of joint fluid or tissue sample
Description: During a puncture or joint surgery planned as part of the routine care of the patient, a part of the joint fluid or tissue sample will be collected in order to carry out the analyzes planned for the research.
Study NCT05717114 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Pecs block
Description: (Pecs block):the block will be performed with the patients in the supine position.The infraclavicular and axillary regions will be cleaned with antiseptic solution. the inplane technique will be used from proximal and medial to distal and lateral in an oblique manner at dermatome level T2and T3.The puncture site was infiltrated with 2%lidocaine and once the structures is identified with ultrasound.
Study NCT05717114 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pecs block
Description: (Pecs block):the block will be performed with the patients in the supine position.The infraclavicular and axillary regions will be cleaned with antiseptic solution. the inplane technique will be used from proximal and medial to distal and lateral in an oblique manner at dermatome level T2and T3.The puncture site was infiltrated with 2%lidocaine and once the structures is identified with ultrasound.
Study NCT06086080 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard care
Description: Bracing and physical therapy
Study NCT06086080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: Bracing and physical therapy
Study NCT06086080 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Taping
Description: The patient is treated with tape in special configuration (McConell modified) for the patella + standard care
Study NCT06086080 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Sham taping
Description: Taping with no treatment disposition
Study NCT05093712 — intervention group
Intervention type: OTHER
Intervention: Educational Intervention
Description: Watch educational video
Study NCT05093712 — intervention group
Intervention type: OTHER
Intervention: Survey Administration
Description: Complete surveys
Study NCT06372912 — intervention group
Intervention type: PROCEDURE
Intervention: Sleeve gastrectomy, Roux-en-Y gastric bypass, mini-gastric bypass, SADIS, intragastric balloon insertion, and gastric band placement are bariatric surgeries.
Description: Sleeve gastrectomy: reduces stomach size. Roux-en-Y gastric bypass: limits calorie absorption. Mini gastric bypass: achieves weight loss with fewer incisions. SADIS: combines sleeve gastrectomy with small bowel bypass. Intragastric balloon: reduces stomach volume. Gastric banding: restricts food intake.
Study NCT05470322 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Er: YAG laser
Description: Patients will be treated with laser for their HS scarring.
Study NCT05403957 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: TID video
Description: Main intervention: A video introducing the tobacco industry's marketing tactics to attract children and adolescents to smoke and their manipulation of tobacco control policy formation.~Booster intervention: 6 screenshots from the video and 6 true or false questions.
Study NCT05403957 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: TID worksheet
Description: Main intervention: A worksheet using pictures and texts to introduce the tobacco industry's marketing tactics to attract children and adolescents to smoke and their manipulation of tobacco control policy formation.~Booster intervention: 8 pictures from the TID worksheet in the main intervention and 6 true or false questions.
Study NCT05403957 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: SSB worksheet
Description: Main intervention: A worksheet using pictures and texts to introduce the beverage industry's marketing tactics to attract children and adolescents to drink SSBs and the health risks of SSBs.~Booster intervention: 8 pictures from the SSB worksheet in the main intervention and 6 true or false questions.
Study NCT05002725 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocain
Description: 300mg (20ml) will be injected
Study NCT05002725 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocain
Description: 300mg (20ml) will be injected
Study NCT06537791 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-Based Rehabilitation Program
Description: Physical Therapy: 32 sessions, 60 minutes each Occupational Therapy: 8 sessions, 60 minutes each Nutrition Counseling: 4 sessions, 60 minutes each Psychological Support: 8 sessions, 60 minutes each Nursing and Podiatry Care: 4 sessions, 60 minutes each Total Duration: Approximately 4 months
Study NCT05790356 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fecal Microbial transplant
Description: Fecal microbial transplant will be investigated for its effect on gut bacterial composition in patients with rheumatoid arthritis.
Study NCT05790356 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsules
Description: The placebo capsules will not contain FMT but will have the same appearance.
Study NCT04743973 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Muse S™ Headband system
Description: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Study NCT06720350 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Romosozumab and Denosumab Combination Therapy
Description: Romosozumab 210mg per month and denosumab 60mg per 6 months will be applied
Study NCT06720350 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Romosozumab Prefilled Syringe [Evenity]
Description: Romosozumab 210mg subcutaneously per month
Study NCT06720350 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Denosumab (Prolia)
Description: Denosumab 60 mg subcutaneously per 6 months
Study NCT06719856 — intervention group
Intervention type: DRUG
Intervention: 18-FDG
Description: All study participants will undergo one 18F-FDG PET/ CT scan.
Study NCT06707389 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: autologous blood monocyte vesicles (lower dose)
Description: 20 ml peripheral venous blood was extracted from each patient, anticoagulated with heparin and diluted with PBS. Peripheral blood mononuclear cells were isolated by Ficoll stratified solution. Extracellular vesicles of mononuclear cells were extracted by gradient centrifugation (800g centrifugation at 4 ℃ for 10 minutes, then 2000g centrifugation at centrifuged at 4 ℃ for 10 minutes and then 16000g centrifugation at 4 ℃ for 30 minutes. The precipitate was taken as monocyte vesicle and stored in refrigerator at 4 ℃. For intratympanic injection, precipitate was dissolved in 0.2 ml of lidocaine and 0.8 ml of sterilized injection water. Intratympanic injection of apoVs was performed three times a week.
Study NCT06707389 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Methylprednisolone
Description: 40mg of methylprednisolone was dissolved in 0.2 ml of lidocaine injection and 0.8 ml of sterilized injection water. Intratympanic injection of methylprednisolone was performed three times a week.
Study NCT06707389 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: autologous blood monocyte vesicles (higher dose)
Description: 50 ml peripheral venous blood was extracted from each patient, anticoagulated with heparin and diluted with PBS. Peripheral blood mononuclear cells were isolated by Ficoll stratified solution. Extracellular vesicles of mononuclear cells were extracted by gradient centrifugation (800g centrifugation at 4 ℃ for 10 minutes, then 2000g centrifugation at centrifuged at 4 ℃ for 10 minutes and then 16000g centrifugation at 4 ℃ for 30 minutes. The precipitate was taken as monocyte vesicle and stored in refrigerator at 4 ℃. For intratympanic injection, precipitate was dissolved in 0.2 ml of lidocaine and 0.8 ml of sterilized injection water. Intratympanic injection of apoVs was performed three times a week.
Study NCT06732258 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Low-dose radiotherapy
Description: The LDRT deals with primary tumour in a 15 Gy of 5 fractions over five days, starting from Day 1 in the first cycle.
Study NCT06732258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tifcemalimab injection
Description: 100 mg or 200 mg q3w until disease progression or intolerable toxicity;
Study NCT06732258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: 240 mg q3w until disease progression or intolerable toxicity;
Study NCT06732258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: 75 mg/m2 q3w for 4-6 cycles;
Study NCT06732258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: AUC = 5, q3w for 4-6 cycles;
Study NCT06732258 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: 100 mg/m2, d1, d2, d3, q3w for 4-6 cycles;
Study NCT06751056 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cervical Traction Device
Description: Participants will use their home neck traction devices daily for 12 weeks, while continuing their prescriptions for gabapentin or pregabalin.~At study initiation and every 2 weeks thereafter for a total of 12 weeks, they will receive an electronic survey assessing their itch score. Based on survey results, they will receive a call from the study team to adjust their dosage of gabapentin or pregabalin by up to 33%.
Study NCT06749015 — intervention group
Intervention type: OTHER
Intervention: Non interventional study
Description: Non interventional study
Study NCT06750419 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 89Zr-TLX250 PET/CT
Description: 89Zr-TLX250, is a chimeric monoclonal antibody (INN name: girentuximab) with specificity for the CAIX (carbonic anhydrase 9) antigen, radiolabelled with the positron emitting radiometal zirconium- 89. Girentuximab has a CAS number of 916138-87-9. The chemical formula, without the 89Zr and the desferrioxamine, is C6460H1006N1718O2018S48 with a molecular mass of 146.5 kg/mol.~89Zr-TLX250 is formulated as a solution for IV administration in glass vials at the nominal dosage strength of 37 MBq (±10%) for single IV use. The mass dose of 89Zr-TLX250 to be used in this Phase 3 study will be 10 mg, labelled with 37 MBq (±10%) 89Zr per dose.
Study NCT05969665 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fitbit Inspire 2
Description: A smartwatch (Fitbit Inspire 2) with its respective app will be worn by the patients in the intervention group for 3 months.
Study NCT05969665 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Abbott Freestyle Libre 3
Description: A continuous glucose measuring device (Abbott Freestyle Libre 3) with its respective app will be worn by the patients in the intervention group for 3 months.
Study NCT04704778 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Transcutaneus electrostimulation therapies
Description: Sterile steel acupuncture needles of 0.25x13mm, disposable AcuBEST brand, and portable electro-stimulator equipment KWD- will be used. The superficial area of the skin of the masseter muscle will be cleaned with alcohol.~Two needles will be placed in each masseter muscle, the area to be punctured is the origin of the masseter muscle or superficial area of the mandibular condyle anterior to the atrial tragus approximately 1cm away, insertion of the masseter muscle at the angle of the mandible. The two double alligator cables will be connected to the head of the needles. The positive pole will be connected at the origin of the masseter muscle and the negative pole at the insertion.~The parameters to be used will be are two frequency bands (210Hz-10140Hz.); amplitude 3050 volts, pulse duration: 40100 msec; and the output intensity: 0.70 (for 100Hz). The treatment time will be 20 minutes.
Study NCT04704778 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Percutaneus electrostimulation therapies
Description: Kendall® MediTrace 100 conductive adhesive ECG electrodes (pediatric) 2.4 cm in diameter, and portable KWD-808 electrostimulator equipment will be used.~The superficial area of the skin will be cleaned, two electrodes will be placed on each muscle (superficial area of the mandibular condyle and at the angle of the jaw). The current leads will then be connected to the KWD-808 electroacupuncturist to the patient.~Current will be transmitted with a square waveform, 210Hz-10140Hz of frequency, 3050 volts of amplitude and 40100 msec pulse time. The treatment time will be 20 minutes.