AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06245070 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sham transcranial direct current stimulation
Description: HD electrodes (diameter of 1.2 cm) will be placed on the participants' skull using an HD-tDCS cap (Soterix Medical Inc. New York) and based on 5-10 international montage. Sham stimulations will be delivered by a 9 MxN Soterix HD-tES device. In the sham tDCS condition, the current is only on for 30 seconds before it is ramped back down to 0 milliamps (mA), although the electrodes are still worn for 20 minutes.
Study NCT06531603 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bupivacaine wound infilteration
Description: drug was given at the end of surgery
Study NCT06531603 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bupivacaine plus dexmedetomidine wound infilteration
Description: drug was given at the end of surgery
Study NCT05131893 — intervention group
Intervention type: DRUG
Intervention: Docetaxel
Description: chemotherapy
Study NCT05512221 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GBAT+I, GBAT+E - Phase I
Description: Phase I is the development phase, which is informed by the study team's previous pilot study and autistic advisors. It will include the development of engagement booster materials. Booster materials will be tested in 2 groups (GBAT+I and GBAT+E) of six participants each. Groups include GBAT+Individual (GBAT+I; individual sessions to supplement the 10 group sessions) and GBAT+Engagement Booster (GBAT+E; supplemental materials). The first 4-6 eligible adults recruited will participate in GBAT+I and the second 6 eligible adults recruited will participate in GBAT+E. Both groups will consist of 10 weekly 60-90-minute GBAT group sessions. Participants in the GBAT+I group will also attend 30-minute individual booster sessions, approximately between Weeks 4-5, 5-6, 6-7, and 7-8. Participants in the GBAT+E group will be asked to use booster materials in between group sessions (e.g., worksheets, goal trackers, interactive learning activities).
Study NCT05512221 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Watchful Waiting and Groups - Phase 2
Description: Phase 2a will include a watchful waiting (WW) condition and assignment to 1 of 2 treatment conditions: GBAT+I or GBAT+E.~Participants will be assigned to WW for 10 wks. They will not receive specific therapeutic services during WW, but a member of the study team will contact them at weeks 1, 2, 4, 6, and 8 to maintain engagement and monitor for clinical deterioration.~After WW, participants will be randomly assigned to one of the treatment conditions (GBAT+I or GBAT+E). All groups will consist of 10 weekly 60-90-minute GBAT group sessions. GBAT+I participants will attend four 30-minute individual booster sessions. GBAT+E participants will be asked to use booster materials between group sessions (e.g., worksheets, goal trackers, interactive learning activities)~WW group size is based on study feasibility and availability of resources. Additional participants will also be recruited at the end of the WW period to supplement group sizes.
Study NCT05512221 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GBAT+IE
Description: Phase 2b will include assignment to GBAT+IE, which includes components of both GBAT+I (individual sessions) and GBAT+E (supplemental materials)~All groups will consist of 10 weekly 60-90-minute GBAT group sessions. Participants in the GBAT+I group will also attend 30-minute individual booster sessions, approximately between Weeks 4-5, 5-6, 6-7, and 7-8. Participants in the GBAT+E group will be asked to use booster materials in between group sessions (e.g., worksheets, goal trackers, interactive learning activities). Participants in GBAT+IE will participate in both the individual sessions and use of booster materials.
Study NCT05953077 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Conversational recasting
Description: The treatment procedure uses 24 treatment doses embedded into child-friendly activities (crafts, book reading, play). Each each consists of a clinician eliciting use of a targeted grammatical form, a child's attempt (correct or incorrect) to use that form, and an immediate clinician repetition of the child's attempt (a recast), correcting any ungrammatical elements as needed. Clinicians must also attempt to gain the child's attention before providing the recast. Treatment sessions are approximately 30 minutes in duration.
Study NCT05953077 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Conversational recasting
Description: The treatment procedure uses 24 treatment doses embedded into child-friendly activities (crafts, book reading, play). Each each consists of a clinician eliciting use of a targeted grammatical form, a child's attempt (correct or incorrect) to use that form, and an immediate clinician repetition of the child's attempt (a recast), correcting any ungrammatical elements as needed. Clinicians must also attempt to gain the child's attention before providing the recast. Treatment sessions are approximately 30 minutes in duration.
Study NCT05390502 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: manual monitoring and general education on use
Description: Patients will receive a standard blood pressure monitor and education on how to use it. Data will be reported as part of usual care.
Study NCT05390502 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: integrated monitoring and local wrap-around hypertension program
Description: Patients will receive a standard blood pressure monitor and a local wrap-around hypertension program. Data will be sent directly to their participating health system.
Study NCT05714527 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Close-loop FiO2 controller
Description: Close-loop FiO2 controller software option provides automated adjustment of the ventilator Oxygen setting to maintain the patient's SpO2 in a defined target range. When using the software option, the user defines the SpO2 target range, as well as the SpO2 emergency limits, and the device adjusts the FiO2 setting to keep the patient's SpO2 in the target range.
Study NCT05714527 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional
Description: Conventional FiO2 adjustment by the clinician according to SpO2 values, by using the manual FiO2 knob.
Study NCT05424471 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Family Spirit Nurture (FSN)
Description: The FSN intervention lesson is taught to participants previously randomized into the FSN intervention group during the PECO 1 study. Intervention group participants receive 1 Family Spirit Nurture lesson taught by Family Health Coaches. Mothers will receive the 1 - 45 minute lesson within 1-2 weeks of completing the 4-year Follow-up Assessment. The lesson focuses on age-appropriate parental feeding practices, including snack routines, avoidance of SSBs and promotion of water consumption. The lesson is highly visual and interactive, and incorporates cultural teachings related to child feeding and nutrition that support aims. The Family Health Coaches also provide social support and will facilitate referrals to community resources.
Study NCT05424471 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control Group - Vehicle Safety
Description: The control (vehicle safety) lesson is taught to participants previously randomized into the control group during the PECO 1 study. Control group participants receive 1 - 30 minute lesson with vehicle safety information, taught by Family Health Coaches. Mothers will receive the lesson within 1-2 weeks of completing the 4-year Follow-up Assessment. The Family Health Coaches also provide social support and will facilitate referrals to community resources.
Study NCT05544461 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: eNutri personalised nutrition advice
Description: eNutri is a web-based app that administers an FFQ and delivers PN advice to the user. The advice is generated from their responses in the FFQ and considers their sex and dietary restrictions (such as whether they eat meat) so the reports are unique to each participant. This report (referred to as a 'healthy eating report') will also include an interactive component, allowing the participant to reflect on the advice received and set personal healthy eating goals to motivate behaviour change. The messages presented in the report have been developed by the eNutri Team, including a registered dietitian and registered nutritionist and are in line with UK dietary guidelines (primarily the EatWell Guide).
Study NCT05933434 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Allogenic adipose derived mesenchymal stem cells (AD-MSC)
Description: Laboratory isolated, cultivated and cryopreserved allogenic adipose derived mesenchymal stem cells (AD-MSC) from health donors undergoing cometic plastic surgery will be thawed on the injection day and formulated in 10 mL saline. The AD-MSCs will then be intraarticular injected using ultrasonic guidance.
Study NCT05933434 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: 10 mL saline will be intraarticular injected using ultrasonic guidance.
Study NCT05875038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video system
Description: The video surveillance system will analyze the position of subjects in real time using algorithms based on artificial intelligence. The system works continuously without video capture and sends an alert with a photo if a person is lying down after a fall. The alert is confirmed after an operator has checked the photo capture on a dedicated platform.
Study NCT05875038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tele-alarm
Description: Tele-alarm
Study NCT05875038 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tele-alarm
Description: Tele-alarm
Study NCT05131893 — intervention group
Intervention type: DRUG
Intervention: paclitaxel
Description: chemotherapy
Study NCT05131893 — intervention group
Intervention type: DRUG
Intervention: trastuzumab
Description: biological treatment
Study NCT05131893 — intervention group
Intervention type: DRUG
Intervention: pertuzumab
Description: biological treatment
Study NCT05131893 — intervention group
Intervention type: DRUG
Intervention: Capecitabine
Description: chemotherapy
Study NCT05838729 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RiMO-301
Description: A single dose of RiMO-301 will be administered via an intratumoral injection.~PD-1 inhibitor (pembrolizumab or nivolumab) will be administered via a 30-minute intravenous infusion until disease progression or unacceptable toxicity.~Patients will receive hypofractionated radiation in 5 fractions.
Study NCT05524324 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: CRT ON (biventricular pacing) / CRT OFF (inactive or univentricular pacing)
Description: Patients randomized to the CRT ON / CRT OFF arm will undergo a first intervention to activate their device and then a second intervention for 3 months to inactivate their device.
Study NCT05524324 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: CRT OFF (inactive or univentricular pacing) / CRT ON (biventricular pacing)
Description: Patients randomized to the CRT OFF / CRT ON arm will undergo a first intervention to inactivate their device and then a second intervention for 3 months to activate their device.
Study NCT06573671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Chitotriosidase
Description: The amount of patients with increased chitotriosidase, and the extent of elevation of chitotriosidase
Study NCT06573671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Mass spectrometry
Description: to show PVP presence in histiocytes of injecting drug users compared to controls
Study NCT06573671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: X-ray spectromicroscopy
Description: to show PVP presence in histiocytes of injecting drug users compared to controls
Study NCT06573671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Fluorescence microscopy
Description: to show PVP presence in histiocytes of injecting drug users compared to controls
Study NCT06573671 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Transcriptomics
Description: To describe pathologic signals of PVP-exposed in vitro histiocytes of injecting drug users compared to control samples
Study NCT05660616 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: The study includes patients with unresectable malignant pleural mesothelioma who received at least 4 cycles of first line platinum (Cisplatin or Carboplatin) and pemetrexed combination chemotherapy~* Response after first line treatment will be assessed by the modified Response Evaluation Criteria in Solid Tumors (mRECIST) version 1.1 for pleural mesothelioma.~* Patients will be randomized according to a (1:1) ratio to either Arm 1: Administration of maintenance gemcitabine (1000 mg/m²) on days 1 and day 8, in cycles of 21 days plus supportive care Arm 2 (control arm): best supportive care alone.~* Cases will be evaluated every cycle clinically and every three cycles radiologically with CTs.
Study NCT05660616 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: supportive care
Description: supportive care
Study NCT05660616 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: supportive care
Description: supportive care
Study NCT06000839 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: (D0) Intradermal injection - micropapula technique
Description: First injection of the product (3ml) in the medium and lower third of the face (whole face excepted forehead)
Study NCT06000839 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: (D14) Intradermal injection - micropapula technique
Description: Second injection of the product (3ml) in the medium and lower third of the face (whole face excepted forehead)
Study NCT06000839 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: (D28) Intradermal injection - micropapula technique
Description: Third injection of the product (3ml) in the medium and lower third of the face (whole face excepted forehead)
Study NCT06364124 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: evolocumab
Description: Preoperative subcutaneous injection of Evolocumab (420mg)，Atorvastatin 40mg per day
Study NCT06364124 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: standard post-treatment for STEMI
Description: standard post-treatment for STEMI
Study NCT06364124 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: standard post-treatment for STEMI
Description: standard post-treatment for STEMI
Study NCT06236958 — intervention group
Intervention type: DEVICE
Intervention: Transnasal jejunal tube
Description: A naso-jejunal tube was placed in the operation, which is placed 15 cm below Traitz's ligament. A short-peptide enteral nutrient solution was heated by an enteral nutrient pump and infused into the patients within 24 hours after the operation. Before and at the end of the infusion, physiological saline was given to flush the tube, and at the end of the infusion, the catheter was closed to prevent liquid reflux and blockage of the tube. The catheter should be clamped shut at the end of the infusion. During the infusion period, the patient's gastrointestinal tolerance was dynamically evaluated. According to the results of a regular review of nutritional indicators, including hemoglobin, albumin, electrolytes, liver and kidney function, etc., increase the amount of enteral nutrients; remove the nasojejunal tube when the patient has no abdominal distension after exhaustion and feeding; and change to feeding through the mouth.
Study NCT06236958 — intervention group
Intervention type: OTHER
Intervention: Transvenous access
Description: A uniform drip of nutritional solution was started 24 hours postoperatively. Configuration of nutritional solution: glucose and medium/long-chain fat emulsion as the main energy substances to provide calories, calculated at 30 \~ 35 kcal/(kg-d), glucose-fat ratio is 6:4, pancreatic glucose ratio for those without a history of diabetes mellitus is 1:6 \~ 8, and for diabetic patients depending on the level of glucose, pancreatic glucose ratio is 1:3 \~ 4, and then assisted with subcutaneous injections of insulin to control glucose, if necessary. Pay attention to the total amount of rehydration fluid, electrolytes, vitamins, and trace elements supplemented. Mix the nutrient solution evenly in the laminar flow clean table and infuse it through the route at 2500\~3000 ml/d; the infusion time is 8\~12 h/d. After exhaustion, start to eat through the mouth.
Study NCT05627895 — intervention group
Intervention type: OTHER
Intervention: Neurofeedback
Description: Participants will be shown their brain activity measured in real-time using an MRI scanner. They can then use mental strategies, such as imagination to influence and regulate this activity.
Study NCT06361511 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Linoleic Acid Foods
Description: Two food products containing 6g of high linoleic safflower oil each will be consumed each day for a total of 12g daily
Study NCT06361511 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: High Oleic Acid Foods
Description: Two food products containing 6g of high oleic safflower oil each will be consumed each day for a total of 12g daily
Study NCT05040711 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Coach
Description: This study will use Mindfulness Coach, an iOS- and Android-based app designed to deliver a mindfulness training course centered on Veteran's Affairs (VA) protocols. Developed by the VA's National Center for PTSD, the app provides an engaging introduction to MT, regardless of specific psychiatric illness or patient population. The app provides a training plan with 14 sequential levels, a practice now area with evidence-based mindfulness audio exercises, assessments using the Five-Factor Mindfulness Questionnaire Short Form (FFMQ-SF)90, and education about mindfulness. To progress to the next level, the user must interact with every element. The training plan levels include psychoeducation and exercises (guided meditations and seated practices), which increase in duration as users progress. Levels 1,7 and 14 also include an assessment with the FFMQ-SF. The practice now area has guided meditations to practice new skills.
Study NCT05040711 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator
Description: A a widely available health and wellness app that provides users with daily content on general health, WebMD, will serve as the attention control. Similar health-based apps have been used as controls in other mHealth psychotherapy intervention trials.100,101 The control group will be instructed to access the app 4x/week (same as intervention group) and will receive an orientation and 2 booster sessions as well. I considered other control group options including treatment as usual, but attention control was selected due to the variability of treatment as usual.
Study NCT06572826 — intervention group
Intervention type: OTHER
Intervention: Cardiac Rehabilitation intervention
Description: The cardiac rehabilitation program for post-CS patients includes respiratory physiotherapy, muscle strengthening and endurance training such as walking, treadmill exercises, and cycling, all tailored to the patient's capabilities. Cardiovascular training involves interval and continuous aerobic exercises to improve heart function. The program emphasizes secondary prevention strategies, including lifestyle changes and medication management. Neuromotor rehabilitation addresses sarcopenia and polyneuropathies through targeted exercises like balance training, gait retraining, and the use of advanced technologies like functional electrical stimulation (FES), robotic devices, and virtual/augmented reality. Cognitive-behavioral therapy (CBT) helps manage the psychological effects of severe cardiovascular events. The program also includes speech and occupational therapy, planning for home reintegration, and telerehabilitation to ensure long-term recovery.
Study NCT04962659 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Music and Songwriting
Description: The Mindfulness-Based Music and Songwriting (MBMS) program involves up to 8 weekly sessions (\~1 hour each) delivered via telehealth. During sessions, the participant works with a therapist (e.g., board-certified music therapist) to learn and apply mindfulness practices via music-based meditations and mindful songwriting. Supported by the therapist, participants write two songs during the program.
Study NCT06002425 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Clinician-Directed Treatment Plan
Description: In this approach, clinicians do not employ any technological assistance and rely solely on their professional expertise and experience to formulate treatment plans for participants.
Study NCT06002425 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ChatGPT-Assisted Treatment Plan
Description: In this approach, clinicians utilize the ChatGPT technological tool, formulating treatment plans for participants based on its suggestions and their own professional expertise.
Study NCT04678700 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest physiotherapy post-covid19
Description: The sessions are divided into the following modules;~* Directed abdominal-diaphragmatic ventilation (10 times).~* Costal expansion exercises with the help of flexion and abduction of the upper limbs. (10 times)(1).~* Self-passive stretching of the ribcage and neck muscles, accessory to inspiration. The purpose of the stretching will be to increase the flexibility of the muscles to improve the vital capacity as has already been evidenced in other respiratory diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (25)(26).~Relaxation time;Jacobson's progressive relaxation; we scan the body's condition.~Post-session evaluation by taking the respiratory frequency/ min and the Borg's dyspnea index, and level oxigen after the exercises.