AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05868369 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iVR Group
Description: On the day of surgery, the iVR group will receive a 30-minute sessions or dose of iVR therapy in the ambulatory post-anesthesia care unit (PACU) during their stay. The three distraction-based or skills-based iVR modules will consist of either 1) Mindful Escape; 2) Empowered Breathing; or 3) Relaxation videos. The iVR group will be sub-randomized into receiving only one of the three types of modules. The modules will start approximately 30 minutes upon arriving in PACU and will last approximately 30 minutes.
Study NCT05868369 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard pain management regimen
Description: In the ambulatory post-anesthesia care unit (PACU) during their stay with have standard postoperative pain protocol (including a pre-operative local field block).
Study NCT05868369 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Standard pain management regimen
Description: In the ambulatory post-anesthesia care unit (PACU) during their stay with have standard postoperative pain protocol (including a pre-operative local field block).
Study NCT06724263 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: B1962
Description: B1962 has higher VEGF anti angiogenic activity than its competitors. Phase I clinical trials have shown that B1962 has excellent safety and promising therapeutic effects. Large scale clinical studies may achieve better therapeutic effects than similar competitors targeting the same target
Study NCT06723769 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: rTMS treatment
Description: Repetitive transcranial magnetic stimulation (rTMS) is a new physiotherapy technique for the treatment of PSD Compared to other strategies, it has the advantages of simple operation, non-invasive, painless, and safe. Studies have comprehensively shown that rTMS can effectively improve depressive symptoms in PSD patients
Study NCT06723769 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: conventional treatment
Description: general treatment of stabilizing vital signs (such as antidepressants, stabilizing blood pressure, stabilizing blood sugar, etc. ) and conventional rehabilitation treatment (hemiplegic limb comprehensive training, swallowing speech training, cognitive perception training, etc. ).
Study NCT06722456 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Analysis of protein signatures in stool samples
Description: Stool protein signatures are to be established in parallel to standard clinical evaluation of the intestinal inflammatory activity.
Study NCT06721988 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: oxycodone and parecoxib sodium combinations
Description: Participants will receive 0.1ml/kg oxycodone (1mg/ml) and 2 ml parecoxib sodium (20 mg/ml) combinations after the anesthesia induction but before the surgical incision. Oxycodone is administered 5 minutes after parecoxib sodium administration.
Study NCT06721988 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo and parecoxib sodium combinations
Description: Participants will receive 0.1ml/kg placebo (0.9% saline) and 2 ml parecoxib sodium (20 mg/ml) combinations after the anesthesia induction but before the surgical incision. Placebo is administered 5 minutes after parecoxib sodium administration.
Study NCT06722040 — intervention group
Intervention type: OTHER
Intervention: Implementation of a pediatric triage track
Description: In 2023, a pediatric triage track was implemented at MH1813 to route calls concerning children to specialists in pediatrics, ensuring better expertise.
Study NCT06722794 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Novel Technique for Fixating the Plate of Ahmed Valve to the Sclera Using a Single Flanged Prolene Suture
Description: This novel technique of fixating the plate of Ahmed glaucoma valve to the sclera using a single flanged prolene suture is an efficient, safe, fast, and reproducible technique that combines the benefits of both fixing the plate providing excellent stability without the complications of free plate techniques and at the same time, minimizing both the risks of conventional old valve plate fixation techniques and the concerns of the relative technical difficulty of suturing due to the difficult access to the posterior globe
Study NCT06722001 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Brief insomnia intervention interactive e-book
Description: The control group learned through paper health education leaflets and traditional oral explanations; the experimental group used interactive e-books to intervene in learning Brief Behavioral Treatment of Insomnia.
Study NCT06722001 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: traditional paper handout
Description: The control group learned through paper health education leaflets and traditional oral explanations; the experimental group used interactive e-books to intervene in learning Brief Behavioral Treatment of Insomnia.
Study NCT06722144 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Animal-assisted Therapy
Description: By the professor leader makes social interaction, and helping residents with rehabilitation through the Doctor dogs.
Study NCT06723730 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Upper Quadrant Core Strengthening protocol
Description: Upper Quadrant Core Strengthening protocol Core strengthening protocol will comprise of following four week protocol.~1. Week one Scapular postural correction and shoulder shrugging exercises~2. Week two External rotation at 0 degree~3. Week three Internal rotation at 0 degree~4. Week four Standing row at 45 and 90 degree , Anterior shoulder stretch and Thoracic exercise in sitting
Study NCT06723730 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mobilization with movement
Description: In addition to upper quadrant core strengthening protocol participants will also perform mobilization with movement.~Mobilization with movement protocol will comprise of following forms.~1. Acromioclavicular joint glides~2. Scapular glides~3. Glenohumeral joint glides ( inferior glides, postero-lateral glides, postero-inferior)
Study NCT06722313 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Gametes (sperm or second polar bodies, MI eggs) or arrested embryos were reserved for identification of a proband
Description: 1. Targeted deep sequencing for mosaicism detection for patients with suspected gonadal mosaicism, eg. Repeated similar abortion due to the same variant while the couple were tested negative for the variant in the peripheral blood.~2. Ovarian stimulation, embryo culture, biopsy and vitrification as routinely used in the IVF clinical practice.~3. Gametes and arrested embryo preservation by the embryo laboratory during embryo culture.~4. Genetic testing, including multiple displacement amplification for WGA, variant sequencing in WGA products and Infinium Chip protocol for amplified DNA and haplotype analysis
Study NCT06722105 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 2 infusions of MSC
Description: 1 MSC(AT) (2x10\^6 cells/kg) injection at M0 and 1 MSC(AT) (2x10\^6 cells/kg) injection at M3
Study NCT06722105 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: 1 infusion of MSC
Description: 1 MSC(AT) (2x10\^6 cells/kg) injection at M0 and 1 placebo injection at M3
Study NCT06722105 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo at M0 and M3
Study NCT06724354 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
Description: Surgical site infections are a preventable cause of morbidity following surgical procedures. Strategies to reduce SSI rates should address preoperative, perioperative and postoperative factors, and multiple interventions can be combined into 'bundles'. Adoption of these measures may reduce SSIs, but this is dependent on a high level of package compliance. The aim of this study was to evaluate the change in SSI rates after the implementation of the SSI prevention package after neurosurgical operations. It is thought that if the results of our study are positive, the package form created will be pioneered for use in other patient groups. In addition, reducing SSI rates will shorten the postoperative recovery time of patients and reduce hospital costs.
Study NCT06219733 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vactosertib
Description: 200 mg PO BID 5 days on / 2 days off
Study NCT06219733 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Imatinib
Description: Imatinib 400 mg PO QD daily
Study NCT06161766 — intervention group
Intervention type: DRUG
Intervention: terlipressin or noradrenalin plus albumin
Description: Patients with clinical suspicion of HRS-AKI or HRS-AKI-like syndrome in case of previously diagnosed CKD who had received vasoactive treatment for the management of HRS, as defined by the administration of terlipressin or noradrenalin plus albumin.
Study NCT05869188 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Isotretinoin
Description: * Evaluate serum irisin level in acne vulgaris and compare it with healthy control .~* Evaluate the effect of systemic isotretinoin on serum irisin in acne vulgaris patients .
Study NCT06456424 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Phage therapy
Description: Bacteriophage cocktail consisting of phages BP13 and J1P3
Study NCT04726787 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Bridging Radiotherapy
Description: Bridging Radiotherapy will start immediately after leukapheresis and before Tisagenlecleucel treatment
Study NCT06063538 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CardiaMend in Combination with Amiodarone
Description: The first three patient will receive 600 mg amiodarone into the intact pericardial space. Amiodarone serum levels will be tested at post operative days 2 and 6. The study will only proceed if there is a serum amiodarone level less than 25% of the normal therapeutic level. This should insure lack of systemic toxicity. After the first 3 patients have demonstrated low amiodarone blood levels, a total of up to 60 patients will be enrolled in the study.~The CardiaMend patch will saturated per the instructions and be sutured into place. Amiodarone will be dripped directly over the heart.
Study NCT06039449 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VYD222 (pemivibart)
Description: Participants will be dosed on Day 1 followed by redosing at Month 3 (approximately 90 days) with VYD222.
Study NCT06039449 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: Participants will be dosed on Day 1 followed by redosing at Month 3 (approximately 90 days) with Placebo.
Study NCT04321525 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive-behavioral therapy
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session
Study NCT04321525 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personal Construct Therapy
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session
Study NCT04321525 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Personal Construct Therapy with virtual reality
Description: 10 individual one-hour sessions, with one or two booster sessions at about three months after the tenth session
Study NCT05257876 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing exercise
Description: Participants will receive breathing exercise training, and a 4-week self exercise
Study NCT06096532 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 75 gm oral glucose load
Description: Consumption of 75 gm oral glucose load in order to test nutrient responsiveness
Study NCT06096532 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 75 gm oral glucose load
Description: Consumption of 75 gm oral glucose load in order to test nutrient responsiveness
Study NCT05748145 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metronidazole Oral
Description: Metronidazole will be administered per os at 500 mg x 3/day, for 10 days prior to surgery.
Study NCT06023472 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: microfluidic chip
Description: Microfluidic chip method has been used for sperm sorting in order to select the most motile and morphologically normal sperm for use in assisted reproductive technologies (ART) such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Study NCT03003195 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: P10s-PADRE
Description: All research participants will receive the Mimotope P10s-PADRE/MONTANIDE ISA 51 VG vaccine via subcutaneous (SC) injection for a total of 4 vaccinations.
Study NCT06048952 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Music Therapy
Description: Huseyni maqam, Pentatonic music
Study NCT05560607 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZD7503 Intervention
Description: Part A: Participants will be screened for histologic evidence of NAFLD or NASH and all eligibility criteria in part A prior to enrollment in part B.~Part B: Participants consented to part B will be administered the study drug over the course of 31 days. At the end of the study a liver biopsy will be collected to measure for endpoints.
Study NCT06551285 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ovapro (Lifepro)
Description: Dietary supplement that contains inositol, vitamin D, zinc, and curcumin.
Study NCT06023472 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: density gradient centrifugation
Description: Density-gradient centrifugation is a commonly used method for sperm separation and purification. It is a technique that involves layering a semen sample on top of a gradient of different densities of a solution, typically a mixture of colloidal silica and sucrose, and then centrifuging the sample. The centrifugal force causes the sperm to migrate through the gradient, where they become separated based on their density.
Study NCT05670158 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: Blood will be collected into 2 EDTA and 1 heparin tube. The 2 EDTA tubes (4ml of blood in each) will be transported on ice to the proteomics platform in the next three hours, centrifuged and stored on -80 degrees Celcius in low-binding tubes for further molecular analysis. 1 heparin tube (5mL) will be sent to the Bacteriology-Virology Department for the active PBMC counting.
Study NCT05670158 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Blood sampling
Description: Blood will be collected into 2 EDTA and 1 heparin tube. The 2 EDTA tubes (4ml of blood in each) will be transported on ice to the proteomics platform in the next three hours, centrifuged and stored on -80 degrees Celcius in low-binding tubes for further molecular analysis. 1 heparin tube (5mL) will be sent to the Bacteriology-Virology Department for the active PBMC counting.
Study NCT05670158 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Perilymph sampling
Description: The perilymph collection will be performed during the cochlear implantation surgery at the same time as the round window opening. 5 to 15 microliters will be aspirated using an atraumatic spinal needle mounted onto 1 ml insulin syringe.
Study NCT05433025 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cervigard Neck Collar
Description: A device used to treat neck pain caused by forward head posture
Study NCT05253885 — intervention group
Intervention type: DEVICE
Intervention: Smartphone use
Description: * Smartphone addiction scale (short version) higher than 33~* Smartphone users of 4-5 inches screen size smartphones, weighing 140-160 grams and dimensions less than 159\*79\*9 mm.
Study NCT06309589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: experimental group received UDCA combined with vitamin D3 (1200 IU per day) treatment
Study NCT06369402 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cerebral haemodynamic testing using transcranial Doppler
Description: Measurement of cerebral haemodynamics using transcranial Doppler to insonate the middle cerebral arteries bilaterally testing neurovascular coupling with selected domains from the Addenbrooks cognitive examination III and the digit span forward and backwards.
Study NCT06369402 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ankle-brachial pressure index
Description: Ratio of ankle to brachial blood pressure measured using handheld Doppler at rest and after exercise (six-minute walk test).
Study NCT06369402 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Six-minute walk test
Description: Supervised brisk walk for six minutes. Time and distance to onset of claudication pain and total distance walked (and total time walked if did not complete the full six minutes).
Study NCT05338905 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Palliative Therapy
Description: Receive standard symptom management
Study NCT05338905 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quality-of-Life Assessment
Description: Complete quality of life questionnaire
Study NCT05338905 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Complete quality of life questionnaire
Study NCT05423275 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Negative ion therapy
Description: Negative ion generator
Study NCT05423275 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Light therapy
Description: Fluorescent light box
Study NCT05854719 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Speechreading training with an application
Description: The Optic Track application developed for this intervention will be used in speechreading training. The target is that, during the eight intervention weeks, it would be used for 15 minutes at least three times a week.
Study NCT06260995 — intervention group
Intervention type: OTHER
Intervention: Social Prescribing Link Worker Intermediary Intervention
Description: Social prescribing link workers \[SPLW\] receive referrals from healthcare professionals, community services, or through self-referral. Individuals are referred for social isolation or social needs, frequent healthcare attendance, or to address a pre-existing health issue. SPLW carry out an in-depth assessment of the individual's needs, and then work with the individual over weeks and months to connect them to community services and supports, which can include local physical activities. They use several strategies during this follow-up period, such as instrumental support (doing things for the individual), empowerment and motivation techniques and/or attending activities with the individual. After the SPLW establishes a connection to a local physical activity, the individual enrols and participates in the chosen activity. Local physical activities can include walking groups, local gyms and leisure centres, chair-based exercise, outdoor activities, yoga and tai chi.
Study NCT06260995 — intervention group
Intervention type: OTHER
Intervention: Local Sports Partnership Community Development Officer Intervention
Description: Local sports partnership community development officers \[LSPO\] mainly receive self-referrals, or can receive referrals, to improve physical activity levels of individuals through participation in physical activity groups delivered by the partnership. LSPO do not carry out an in-depth assessment but may carry out screening before explaining/signposting to local physical activities. They use several strategies to connect the individual to local physical activities, such as attending the first session of the group, providing reassurance and practical support, and keeping the person updated and informed as to upcoming groups. After the LSPO establishes a connection to a local physical activity, the individual enrols and participated in the chosen activity. The LSPO continues to support this engagement during the follow-up period. Local physical activities can include walking groups, local gyms and leisure centres, chair-based exercise, outdoor activities, yoga and tai chi amongst others.
Study NCT05679401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Imlifidase
Description: Imlifidase is an immunoglobulin G (IgG)-degrading enzyme of Streptococcus pyogenes that is highly selective towards IgG. The cleavage of IgG generates one F(ab')2- and one homodimeric Fc-fragment and efficiently neutralizes Fc-mediated activities of IgG.
Study NCT05679401 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Plasma exchange (PLEX)
Description: PLEX removes the patient's pathogenic anti-GBM antibodies, by replacement of deficient plasma with a replacement fluid.
Study NCT05679401 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Plasma exchange (PLEX)
Description: PLEX removes the patient's pathogenic anti-GBM antibodies, by replacement of deficient plasma with a replacement fluid.
Study NCT05679401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide (CYC)
Description: Cyclophosphamide's main mechanism of action (i.e. crosslinking of strands of DNA and RNA) results in inhibition of protein synthesis. Hence treatment prevents formation of new anti-GBM antibodies.
Study NCT05679401 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cyclophosphamide (CYC)
Description: Cyclophosphamide's main mechanism of action (i.e. crosslinking of strands of DNA and RNA) results in inhibition of protein synthesis. Hence treatment prevents formation of new anti-GBM antibodies.
Study NCT05679401 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glucocorticoids
Description: Glucocorticoids inhibit the inflammation process.
Study NCT05679401 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoids
Description: Glucocorticoids inhibit the inflammation process.