AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06593444 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thalamic Ventral Intermediate-DBS
Description: Participants will undergo Thalamic Ventral Intermediate-DBS ON with the individual stimulation parameters determined in the parameter determination period, then continue to receive stimulation for the remainder of the study.
Study NCT05546827 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical resection
Description: Surgical resection after receiving neodjuvant combination immunotherapy followed by radiation therapy.
Study NCT06604702 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Autologous Fat Injection for Rectocele
Description: In this procedure, autologous fat is harvested from the patient\&#39;s lower abdomen using a multiport cannula. The fat is then processed via centrifugation to separate the viable fat cells, which are emulsified into nanofat. This nanofat is injected into the submucosal layer of the rectocele through the posterior vaginal wall, using an anoscope for guidance. The procedure is intended to reinforce the rectovaginal fascia, alleviate rectocele symptoms such as obstructive defecation and vaginal bulge, and reduce prolapse recurrence.
Study NCT06587880 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chlorhexidine Gluconate
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction, the patient is instructed to pour 10 ml of the mouthwash into a measuring cup, rinse for 1 minute at an alternative time to teeth brushing. Do not eat or drink for 30 min after use.
Study NCT06587880 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bone Bioactive Liquid
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction.
Study NCT06587880 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Hyaluronic Acid mouthwash
Description: Prescribed for 7 days period 3-4 times a day starting 24 hours post-extraction, the patient is instructed to pour 20 ml of the mouthwash into a measuring cup and rinse for 1 minute, at an alternative time to teeth brushing. Do not eat or drink for 30 mins after use.
Study NCT06587880 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Warm Saline Mouth Rinse
Description: Prescribed for 7 days period 2 times a day starting 24 hours post-extraction.
Study NCT06586944 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Nursing Practices Based On Roy Adaptation Model Integrated With Virtual Reality
Description: After the research groups were formed, a six-session interview programme was created for the participants included in the experimental group (Table...). In the sessions, nursing and psychiatric nursing interventions (psychoeducation, relaxation, awareness, effective coping, cognitive restructuring) based on the Roy Adaptation Model were carried out for the negative situations caused by anxiety and anxiety experienced by individuals. Subjective goals were determined for adaptive or maladaptive behaviour, attitude and thought patterns caused by anxiety-causing stimulus(s) and appropriate nursing interventions from the Nursing Interventions Classification System (NIC) were applied for these goals.Virtual reality-based intervention was effectively used as an important intervention tool in the implementation of the interventions and in the evaluation of the implemented interventions in four sessions of a total of six sessions.
Study NCT06586944 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Roy Adaptation Model
Description: After the research groups were formed, a six-session interview programme was created for the participants included in the experimental group. In the sessions, nursing and psychiatric nursing interventions (psychoeducation, relaxation, awareness, effective coping, cognitive restructuring) based on the Roy Adaptation Model were carried out for the negative situations caused by anxiety and anxiety experienced by individuals. Subjective goals were determined for adaptive or maladaptive behaviour, attitude and thought patterns caused by anxiety-causing stimulus(s) and appropriate nursing interventions from the Nursing Interventions Classification System (NIC) were applied for these goals
Study NCT06591663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Therapy Rating Scale (CTRS)
Description: CBT is the Cognitive Therapy Rating Scale (CTRS), an important assessment tool designed to assess the quality and effectiveness of cognitive therapy sessions.~Mental health professionals, such as therapists and psychologists, commonly use the CTRS to evaluate various aspects of a therapy session. This includes the extent to which the therapist adheres to CBT principles, their skill in applying cognitive and behavioral techniques, their ability to develop a therapeutic relationship with the client, and the overall quality of the session. The scale may also include specific criteria or items that another trained therapist or researcher observes based on their observations during the therapy session (Pingol, 2023).
Study NCT06587126 — intervention group
Intervention type: DEVICE
Intervention: Curie Artificial Intelligence (AI) cough monitor
Description: All patients are given nighttime cough monitors for home use for 3-4 months
Study NCT06594978 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dual-site anodal tDCS over the M1
Description: M1: motor cortex
Study NCT06594978 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: dual-site anodal tDCS over the DLPFC
Description: DLPFC: dorsolateral prefrontal cortex
Study NCT06594978 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham tDCS
Description: sham stimulation
Study NCT06595355 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bevacizumab with oral curcumin
Description: According to the recommendation of the American Association of Ophthalmologists, intravitreal injection of bevacizumab with a standard dose of 1.25mg/0.05ml in each group will be performed three times consecutively at one-month intervals. In the simultaneous intervention group, patients will take daily curcumin tablets (sinacurcumin product) at a dose of 40 mg twice a day for three months (at the same time as the start of bevacizumab intravitreal injection treatment).
Study NCT06595355 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: bevacizumab with oral placebo
Description: Intravitreal injection of bevacizumab with a standard dose of 1.25mg/0.05ml in each group will be performed three times consecutively at one-month intervals. In the control group, patients will be taking daily placebo tablets twice a day for three months (at the same time as the start of bevacizumab intravitreal injection treatment).
Study NCT06599814 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: vital pulp therapy
Description: vital pulp therapy using two bioactive materials TheraCal and RetroMTA as direct pulp caping materials conventionally and test using Diode laser before application of these materials
Study NCT06600529 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Photo-Biomodulation
Description: Application at acupuncture points for 20 seconds each week. using 810nm Laser probe
Study NCT06600529 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Autologous PRP
Description: IV injection of Autologous Plasma Rich Platelets (PRP) on Days 0, 15, 30, and 45.
Study NCT06600529 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Exosome Therapy
Description: IV injection of Umbilical Cord-Derived Exosomes at laser acupuncture points Umbilical Cord-Derived Exosomes
Study NCT06600529 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard Care (in control arm)
Description: Routine conventional including Applied Behavioral Analysis (ABA) for Autism Spectrum Disorder (ASD)
Study NCT06590831 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lactoferrin
Description: to compare between efficacy of lactoferrin alone and lactoferrin with iron for treatment of iron deficiency anemia during 3rd trimester of pregnancy
Study NCT06593028 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Veggie Vouchers pilot
Description: This intervention aims to increase awareness and use of a Supplemental Nutrition Assistance Program (SNAP) fruit and vegetable incentive program in South Carolina among families with young children experiencing food insecurity. To do so, brief education about this SNAP program is delivered by pediatricians to caregivers during well-child visits. Subsequently, caregivers are given 3 free produce boxes as a free trial of this program to incentivize first time use.
Study NCT04895644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: No Hard Collar
Description: The patient in the intervention arm will not wear a Hard Collar for 12 weeks post injury
Study NCT05978167 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methylphenidate
Description: Oral administration of 20 mg Methylphenidate
Study NCT05978167 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methylphenidate
Description: Oral administration of 20 mg Methylphenidate
Study NCT05978167 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Memory reconsolidation
Description: Retrieval of drug-cue memories before extinction.
Study NCT05978167 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Memory reconsolidation
Description: Retrieval of drug-cue memories before extinction.
Study NCT05978167 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Matching placebo pill
Study NCT05978167 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Matching placebo pill
Study NCT05446272 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NIV-NAVA
Description: Infants in the intervention arm will be managed with non-invasive neurally adjusted ventilatory assist (NIV-NAVA) using FDA-approved servos with associated FDA-approved Edi catheter.
Study NCT05446272 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: NS-NIPPV
Description: Infants in the active comparator arm will be treated with non-synchronized non-invasive positive pressure ventilation (NIPPV) through FDA-approved ventilators currently in use at each site.
Study NCT04971954 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nicotine gum
Description: Nicotine (6 mg) will be administered in the form of polacrilex gum that is available as an over-the-counter medication
Study NCT04971954 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo gum
Description: The placebo will also be a commercially available gum that resembles the nicotine gum in flavor, size, shape, color, and texture.
Study NCT06588959 — intervention group
Intervention type: OTHER
Intervention: validity and reliability study
Description: Determination of strength, endurance and exercise capacity of the upper extremities is an important issue in scleroderma management. 6PBRT, which is one of the tests serving this purpose, has been found to be valid and reliable in patients with chronic obstructive pulmonary disease and asthma, but when the literature is reviewed, it is seen that 6PBRT has not been studied in patients with scleroderma. This study was planned as a non-interventional safety study. The study will investigate the validity and reliability of 6PBRT in patients with scleroderma. In this context, the test will be performed 2 times with a 1-hour rest break. Dyspnea and fatigue will be assessed using the Borg scale and muscle oxygenation, heart rate and blood pressure will be recorded before and after 6PBRT. The level of dyspnea and fatigue and baseline values of heart rate will be checked before the second trial to ensure patients are stable. All assessments will be performed by the same physiotherapist.
Study NCT06591559 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Permobil Explorer Mini
Description: The Explorer Mini (Permobil AB, Sweden) is a commercially available, FDA approved powered mobility device intended for young children between 12-36 months of age with mobility limitations (weight limit: 35 lbs; height limit: 39.4 inches). It is lightweight (52 lbs. including battery) and fits in most automobiles (length: 25 inches; width: 19 inches; adjustable height: 29-37 inches). The Explorer Mini runs on a 12-volt battery with a driving range of 3.5 miles and a maximum speed of 1.5 mph, is controlled via a joystick with a 360-degree turning radius, has proportional speed control with 5 speed options, and can be used in a seated or standing position.
Study NCT06591559 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Portable Mobility Aid for Children (PUMA)
Description: The Portable Mobility Aid for Children (PUMA; Enliten LLC) is a portable canopy system that utilizes an overhead support rail structure and a counterweight. The rail structure consists of two rigid parallel beams that mount to the canopy structure and one perpendicular mobile beam that allows for freedom of movement in one direction. Freedom of movement in the opposite direction is achieved by a system of pulleys along the movable beam that connects the harness to a counterweight. The counterweight provides a passive vertical force, counteracting gravity. The PUMA provides 2-dimensional mobility support over 81 ft2 (9 ft x 9 ft). The overhead bar is connected at 4 points to a child-worn harness. Children are free to move through many postures including sitting, crawling, standing, and walking.
Study NCT06587620 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tranexamic acid
Description: Start IV infusion of a loading dose of tranexamic acid 10 mg/kg completed to 50 ml saline over 10 min before induction of anesthesia. IV infusion of tranexamic acid at a dose of 1 mg/kg/h immediately after induction till 15 min before the end of surgery.
Study NCT06587620 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Dexmedetomidine
Description: Start IV infusion of a loading dose of dexmedetomidine 1ug/kg completed to 50 ml saline over 10 min before induction of anesthesia. IV infusion of dexmedetomidine 0.3-0.7 µg/kg/h immediately after induction to maintain Mean Arterial Pressure (MAP) between 60-70 mmHg till 15 min before the end of surgery.
Study NCT06587620 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline (NaCl 0,9 %) (placebo)
Description: IV infusion of 50 ml saline over 10 min before induction of anesthesia. IV saline infusion immediately after induction till 15 min before the end of surgery.
Study NCT06588452 — intervention group
Intervention type: OTHER
Intervention: RECTIFIER - a generative artificial intelligence screening tool
Description: RECTIFIER is a large-language model based, generative artificial intelligence-enabled inclusion and exclusion criteria assessment tool.
Study NCT06588452 — intervention group
Intervention type: OTHER
Intervention: Manual clinical trial screening by study staff
Description: The current gold standard - study staff manually review potentially eligible patients through chart review.
Study NCT06604585 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Parenthood - a journey together. Digital tool to increase security in parenthood, a way to promote public health..
Description: The project involved the development of an internet-based parental support program to be delivered via the national Support and Treatment (Sob) platform and used in primary care to enhance traditional parental support within child healthcare, as needed. The innovation has been developed in collaboration with the Innovation Fund in Västra Götaland. The aim is to increase the experience of parental competence and a sense of security in parenting by reflecting on attitudes and approaches in interaction with the child through an interactive, digital parental support program. The four themes in the parental support program, Parenthood a journey together, are named: Being a good enough parent, understanding one's child, interacting with one's child, and meeting daily challenges as a parent regarding food, sleep, play, screen time, and physical activity. The four modules will include explanatory and psychoeducational texts, written exercises, videos, and homework.
Study NCT06147037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: FPI-2053
Description: FPI-2053 is a bispecific antibody that targets EGFR and cMET
Study NCT06147037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [111In]-FPI-2107
Description: \[111In\]-FPI-2107 is an imaging agent in which indium-111 is conjugated to FPI-2053.~Participants will have a fixed dose of \[111In\]-FPI-2107 followed by imaging scans (with or without pre-administration of FPI-2053).
Study NCT06147037 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [225Ac]-FPI-2068
Description: \[225Ac\]-FPI-2068 is a radiopharmaceutical therapy in which an alpha emitter, actinium-225, is conjugated to FPI-2053.~Participants will be dosed through IV administration every 56 days for up to 3 cycles of the Treatment Period.
Study NCT06599164 — intervention group
Intervention type: OTHER
Intervention: Anthrogenic Muscle Inhibition (AMI) Assessment Protocol
Description: This study involves evaluating Anthrogenic Muscle Inhibition (AMI) of the vastus medialis muscle in futsal players. The intervention includes assessments of muscle strength, AMI using electromyography, ultrasound evaluation, and single-leg vertical jump tests. These evaluations are conducted at different stages throughout the season: pre-season, 4 months in, and at the end of the season. The goal is to compare AMI levels and muscle function between players with ACL injuries and those without.
Study NCT06171009 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Coping Information
Description: A 4-minute audio recording providing common pain coping techniques (e.g., ice, rest, medication, surgery).
Study NCT06171009 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindful Pain Management
Description: A 4-minute audio recording consisting of a 1-minute introduction to mindfulness followed by a 1-minute and 30-second mindful breathing practice and a 1-minute and 30-second mindfulness of pain practice.
Study NCT06587477 — intervention group
Intervention type: OTHER
Intervention: Hormonal profile
Description: Blood for FSH, LH, testosterone
Study NCT06587477 — intervention group
Intervention type: OTHER
Intervention: Semen analysis
Description: Semen analysis
Study NCT06587477 — intervention group
Intervention type: OTHER
Intervention: Questionnaire
Description: The European Male Ageing Study (EMAS) questionnaire
Study NCT04815876 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transperineal MRI-guided prostate biopsy
Description: Transperineal prostate biopsy will be performed under local anesthesia in the office. This approach avoids transrectal needle tracking.
Study NCT04815876 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Transrectal MRI-guided prostate biopsy
Description: Transrectal prostate biopsy is currently the most popular approach to evaluate a positive screening test for prostate cancer.
Study NCT04815876 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antibiotic (prophylaxis)
Description: For men undergoing transrectal biopsy, antibiotic prophylaxis will be administered in accordance with guidelines from the American Urological Association (AUA).~No antibiotic prophylaxis will be administered for men undergoing transperineal biopsy.
Study NCT06705452 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Additional 4D Flow MRI or additional 4D Flow sequence
Description: Additional 4D Flow MRI or additional 4D Flow sequence
Study NCT06704685 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Butylphthalide
Description: Subjects who were initially diagnosed with STEMI and scheduled for PCI were randomly assigned to one of two groups in a 1:1 ratio: a butylphthalide group and a placebo group.
Study NCT06704685 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Butylphthalide placebo
Description: Butylphthalide placebo
Study NCT05232682 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Seed DS-01 Daily Synbiotic
Description: Daily administration of Seed DS-01 Daily Synbiotic (dietary supplement)
Study NCT05444348 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Advance consultation concerning your life and treatment (ACT )
Description: The ACT intervention consists of: an 8 h training day for clinicians including clinical materials such as a conversation aid and conversations guide. 6o minutes ACT-intervention sessions in daily clinic. the patients and caregivers will receive preparatory material prior for the ACT-intervention sessions, and a 30 min follow-up telephone call from the nurse within one week after the ACT-session. Clinicians will receive five sessions of followup supervision within the 24 months of intervention. The 60 min ACT-intervention session is an interdisciplinary conversation with nurse, physician, patient, and caregiver discussing issues of importance of patient and caregiver. The issues are based on the preparatory material focusing on information level and prognosis, patient's and caregiver's values, hopes, fears and worries regarding the future care with progressive disease.
Study NCT04794855 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: laboratory tests
Description: routine laboratory tests and biomarkers tests
Study NCT05413759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmaceutical care in multiprofessional collaboration
Description: In addition to usual practices: medication reconciliation and pharmaceutical motivational interviews with patients (discharge, 2 \& 6 months).~Objective of medication reconciliation (admission): to detect and resolve unintended medication discrepancies between home medication list and treatment and hospital admission medication orders. Objective of medication reconciliation (discharge): to obtain an exact list of medication, to explain the medication modifications during hospitalization.~Objective of the Disease-Modifying Antirheumatic Drugs information interview (discharge): to provide information and to answer questions on the management of treatment, to deal with practical situations to assess patients' self-management skills.~Objective of interviews (2 \& 6 months): to evaluate medications and their daily management, benefits and problems that patient may encounter, to assess the patient's ability to manage the treatment.