AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05328921 — intervention group
Intervention type: DRUG
Intervention: Antihypertensive Agents
Description: Patients with narrow angle glaucoma and on systemic antihypertensive drugs.
Study NCT05328921 — intervention group
Intervention type: DRUG
Intervention: Antihistaminics
Description: Patients with narrow angle glaucoma and on systemic antihistaminic drugs.
Study NCT05947305 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Surgical Blade
Description: Using a 15c blade to de-epithelialize the soft tissue extra-orally
Study NCT05947305 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Mucotome
Description: Using Megagen Mucotome to de-epithelialize the soft tissue intra-orally
Study NCT05947305 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diamond Bur
Description: Using a surgical diamond bur to de-epithelialize the soft tissue intra-orally
Study NCT05947305 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Er:YAG Laser
Description: Using an Er:YAG Laser to de-epithelialize the soft tissue intra-orally
Study NCT06760429 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Subserratus Plane Block
Description: In the RISS group,the linear ultrasound probe was placed in the sagittal plane at the level of the 5th to 6th thoracic vertebrae (T5-6), just medial to the scapula, to identify the trapezius, rhomboid major, and intercostal muscles. A 21-gauge puncture needle was inserted in a cranial-to-caudal direction into the plane between the rhomboid major and intercostal muscles. When there was no blood aspiration, 20 mL of 0.375% ropivacaine was injected. After that, the ultrasound probe was moved caudally and laterally to identify the tissue plane between the serratus anterior and external intercostal muscles for performing the subserratus block at the level of the 8th to 9th thoracic vertebrae (T8-9). The puncture needle was advanced from the previous position, and when there was no blood aspiration again, an additional 20 mL of 0.375% ropivacaine was injected.
Study NCT04881318 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Waist-High Compression Tights
Description: Waist-high compression tights providing 15-40 mmHg of pressure.
Study NCT04881318 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Abdominal Compression Garments
Description: Abdominal compression garment compressing the abdomen, buttocks, and upper thighs.
Study NCT06759883 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: local dishes using the my plate concept
Description: The intervention in this study consists of replacing the ready-to-use therapeutic foods prescribed in phase 2 of the management of acute severe malnutrition with balanced local dishes.
Study NCT06759545 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dietary MOH recommendations and daily addition of 42 ml (three tablespoon) at each morning of EVOOEH
Description: Dietary intervention study: high-risk pregnant women receiving a link to MOH general dietary recommendations for pregnancy (MOH recommendations) with addition of three tablespoon (42 ml) EVOOEH (up to 0.8% free acidity) per day at each morning for four weeks during the first half of pregnancy (gestational ages between 8 to 16 weeks)
Study NCT06759545 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Dietary MOH recommendations
Description: Dietary intervention study: high-risk pregnant women receiving a link to MOH general dietary recommendations for pregnancy (MOH recommendations) for four weeks during the first half of pregnancy (gestational ages between 8 to 16 weeks)
Study NCT06759480 — intervention group
Intervention type: PROCEDURE
Intervention: Laparoscopic radical hysterectomy based on space anatomy
Description: This is a modified laparoscopic radical hysterectomy based on space anatomy. By identifying the vesicouterine ligament and four associated special spaces, the ureter can be completely liberated from the external aspect of the uterus. This skill not only reduces rate of surgical complications but also facilitates optimal tumor resection.
Study NCT06759480 — intervention group
Intervention type: PROCEDURE
Intervention: Abdominal radical hysterectomy
Description: This producre is a classic and traditional radical hysterectomy.
Study NCT06760494 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: the MAPUSE model
Description: Using the MAPUSE model to predict MVI status before surgical resection for HCC patients
Study NCT06759376 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Vibration massage
Description: * Initiation of the stopwatch with the onset of intradialytic muscle cramp,~* Taking a salivary cortisol test,~* Performing vibration massage with a vibration massage device for 10 minutes,~* VAS questioning every 2 minutes during intradialytic muscle cramp,~* Stopping the stopwatch as soon as the patient states that the intradialytic muscle cramp has ended,~* Repeat salivary cortisol test at 20 minutes from the onset of intradialytic muscle cramp.
Study NCT06759376 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static stretching exercise
Description: * Initiation of the stopwatch with the onset of intradialytic muscle cramp,~* Taking a salivary cortisol test,~* Perform static stretching exercise for 10 minutes,~* VAS questioning every 2 minutes during intradialytic muscle cramp,~* Stopping the stopwatch as soon as the patient states that the intradialytic muscle cramp has ended,~* Repeat salivary cortisol test at 20 minutes from the onset of intradialytic muscle cramp.
Study NCT06759376 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Usual Care
Description: * Initiation of the stopwatch with the onset of intradialytic muscle cramp,~* Taking a salivary cortisol test,~* Usual care,~* VAS questioning every 2 minutes during intradialytic muscle cramp,~* Stopping the stopwatch as soon as the patient states that the intradialytic muscle cramp has ended,~* Repeat salivary cortisol test at 20 minutes from the onset of intradialytic muscle cramp.
Study NCT06759363 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sodium-Butyrate
Description: 1000 mg/day of sodium-butyrate
Study NCT04881318 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Medications that modulate heart rate and blood pressure
Description: Medications that modulate heart rate and blood pressure that participants regularly take. These medications include beta-blockers, midodrine, ivabradine and stimulants.
Study NCT06759363 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium Butyrate
Description: 1000 mg/day of calcium-butyrate
Study NCT06760169 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgery with ELIOS laser
Description: This surgery involves visualizing the iridocorneal angle before or after cataract surgery, inserting the ELIOS laser probe into the anterior chamber to come into slight contact with the trabecular meshwork, then pressing the foot pedal, the surgeon activates the laser, which creates a microchannel by photoablating the trabecular meshwork and inner wall of Schlemm´s canal (trabeculostomy) ± 210 um in diameter. This gesture is repeated until 10 microchannels are created. The creation of these microchannels enhances the natural outflow of aqueous humor by bypassing the site of major resistance in the system. The usual duration of the ELIOS procedure is typically few minutes). The rest of the surgery does not deviate from standard phacoemulsification.
Study NCT06760104 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Dental Plaque Detection Using AI Models
Description: 1. AI Model Analysis:~   Description: Intraoral images of participants will be captured using standardized imaging techniques. These images will then be analyzed using various artificial intelligence models specifically designed for detecting dental plaque. The AI models will process the images to identify and quantify the presence of dental plaque.~2. Clinical Assessment:~Description: A qualified dentist will perform a traditional clinical examination of the participants to assess dental plaque using standard examination techniques. This will serve as the reference standard against which the AI models will be compared.~Study Procedures Image Acquisition: Intraoral images will be taken of each participant using \[ intraoral camera\].~AI Model Evaluation: The captured images will be analyzed using different AI algorithms, which may include.
Study NCT06759155 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: de-intensified radiation
Description: Adjuvant radiation will be administered on a de-intensified schedule.
Study NCT05047341 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR0302、[14C]SHR0302
Description: 8 mg SHR0302/ 80 µCi \[14C\]SHR0302, once, D1
Study NCT06009120 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Education
Description: The education program emphasized the characteristics of the oral stage, positive traits that can be acquired when the baby's needs are met during this stage, negative traits that may develop in the baby when their needs are not met, and the relationship between the oral stage and breastfeeding.
Study NCT06552702 — intervention group
Intervention type: OTHER
Intervention: There is no intervention
Description: There is no intervention.
Study NCT04613024 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Topamax
Description: Experiment randomized group will be prescribed Topamax before and after surgery with follow up at regular interval
Study NCT04613024 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gabapentin
Description: Control group will be prescribed gabapentin after surgery with follow up at regular interval
Study NCT06339489 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Testing the serum levels of bone metabolic markers
Description: Testing serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.
Study NCT06231069 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Multi-nutrient supplement
Description: 12 weeks of supplement intake of milk proteins, N-3 PUFAs, creatine, and vitamin D at levels previously shown to augment muscle protein synthesis in young individuals.
Study NCT06231069 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: 12 weeks of short-duration mixed endurance and resistance exercise.
Study NCT06231069 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Exercise
Description: 12 weeks of short-duration mixed endurance and resistance exercise.
Study NCT06758687 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Kinesiotape Application
Description: Before the appropriate taping is applied to the waist area, a small piece of kinesio tape will be attached to the participant's thigh area and an allergy test will be performed. If the participant does not have any complaints within 5-10 minutes, the participant will be taped. The tape to be used in this study will be waterproof, porous, breathable, 5 cm wide and 0.5 mm thick.~After the initial evaluation is completed, kinesio taping will be applied to the paravertebral muscles. First, the participant will be asked to perform trunk flexion while standing with their forearms supported by a table. While the participant is in this position, two I shaped tapes will be attached to the right and left sides of the spine (in the cranial direction) along the paravertebral muscle line without applying tension. Then, the field correction technique will be applied. While the participant is standing with their forearms supported on the table, four I tapes overlapping in
Study NCT05305547 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: S-217622
Description: Administered as a round tablet.
Study NCT05305547 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered as a round tablet.
Study NCT05463263 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STP938
Description: Small molecule
Study NCT04462302 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet-based pain coping skills program
Description: The purpose of this study is to determine if an 8-session Internet-based pain management program can help you better manage your cancer-related pain.
Study NCT06302491 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AND017 capsules
Description: Administer AND017 capsules once per day (QD)
Study NCT06302491 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: AND017 Placebo
Description: Administer AND017 matching placebo capsules once per day (QD)
Study NCT05543837 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capsaicin
Description: Patients will receive a fixed dose of capsaicin
Study NCT05650125 — intervention group
Intervention type: OTHER
Intervention: Biosampling
Description: Biosampling of blood/tumour/adjacent normal tissue
Study NCT05633134 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arteriography and precision preoperative embolization
Description: Arteriography and transcatheter arterial embolization of pelvic tumors 0-24 hours prior to surgery.
Study NCT05633134 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Arteriography
Description: Arteriography of pelvic tumors 0-24 hours prior to surgery.
Study NCT04756596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: DDVIT testing
Description: One randomly selected eye will be included for each study participant. Participants respond to the DDVIT test in standard environmental lighting conditions at 4 m viewing distance. Visual acuity will be evaluated.
Study NCT04756596 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ETDRS testing
Description: The same eye is included for each study participant. Participants respond to the standard ETDRS chart of our Ophthalmology Department in standard environmental lighting conditions at 4 m viewing distance. Visual acuity will be evaluated.
Study NCT04689347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Bevacizumab 5 mg/kg intravenous infusion every 2 weeks
Study NCT05026164 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: CHI-202
Description: Blend of cannabinoids \& other ingredients
Study NCT05026164 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: CHI-101
Description: Placebo
Study NCT01916031 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Study NCT04949607 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Inulin fructooligosaccharide
Description: Subjects will be administered inulin at a starting dose of 1g twice daily (2g/day) and ramping up an additional 2g/day until the final dose of 4g twice daily (8g/day), which will continue on until the end of month 3 (week 12). After the month 3 study visit, inulin dosing will begin to ramp down over the next week.
Study NCT05651399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remimazolam
Description: Patients receive remimazolam at a rate of 1 mg/kg/hr. When a patient's MOAA/S reaches 3 or less, the rate of remomazolam is maintained at a rate between 0.3 mg/kr/hr and 1.0 mg/kg/hr until the end of surgery.
Study NCT05651399 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Patients are administered propofol with an effect-site concentration of 1.0 mcg/mL to 2.5 mcg/mL by target controlled infusion.
Study NCT05505071 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DANTE SPACE sequence
Description: investigational MRI sequence less than 15 minutes
Study NCT04689347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Irinotecan
Description: irinotecan 165 mg/sqm intravenous infusion every 2 weeks
Study NCT04689347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leucovorin
Description: leucovorin 200 mg/sqm intravenous infusion every 2 weeks
Study NCT04689347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 5Fluorouracil
Description: 48-hours continuous intravenous infusion of 5-fluorouracil (5-FU) 3200 mg/sqm every 2 weeks
Study NCT04689347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Temozolomide
Description: Oral temozolomide with progressive dose escalation at inter-patient level over days 1-5 every 28 days. (75 mg/sqm; 100 mg/sqm; 125 mg/sqm or 150 mg/sqm)
Study NCT06305520 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Investigational medical device (SkinPlus-HYAL Implant Lidocaine)
Description: \* In this investigation, the same subject receives both test and control treatments, one on each side of the nasolabial folds (matched pairs design).
Study NCT06305520 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Comparator: Active Comparator Medical Device (RESTYLANE Lidocaine)
Description: \* In this investigation, the same subject receives both test and control treatments, one on each side of the nasolabial folds (matched pairs design).
Study NCT05962502 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab and irinotecan
Description: chemotherapy plus targeted therapy
Study NCT05263440 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial direct current stimulation (tDCS)
Description: Participants will complete a single 30 minutes tDCS session targeting the left DLPFC while sitting in a comfortable position. At the end of the tDCS session possible side effects experienced during the tDCS session will be recorded along with their intensity (rated using the visual analogue scale, 0-10) and duration. The session can be aborted at any time for any reason if the participant wishes.The MINDD STIM tDCS system is composed of a management component, treatment module, single-use sponge patches and supporting patches, a headband to hold in position the sponge patches, and 2 cables. A trained study technician will program the stimulation device through the management component setting to the following stimulation parameters:Stimulation intensity: 2.0 mA or 1.5 mA; Stimulation duration: 30 minutes;Ramp up duration: 30 seconds (beginning of stimulation);Ramp down duration: 30 seconds (end of stimulation)
Study NCT04476355 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Select and Tailor implementation interventions
Description: Based on previously adapted guidelines and the assessment of innovation, adopters and practice environment for barriers and supports, the interventions mainly include patients education, practioners education and system changes.
Study NCT05717452 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Blueberry drink
Description: 22 g freeze-dried wild blueberry (Vaccinium angustifolium) powder mixed with 250 ml water.
Study NCT05717452 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo drink
Description: 22 g placebo powder matched for macronutrients, color, and flavor mixed with 250 ml water.
Study NCT04894084 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: CP321
Description: The primary objective is to evaluate the system performance of the test product. This is done by asking subjects to answer questions throughout the study
Study NCT05072548 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The ABCs of SLEEPING
Description: The intervention is comprised of three components. The first is a sleep check-in which is a questionnaire that is evidence based and evaluates what areas of sleep parents can work on. The second component is the sleep report which summarizes to the parent what areas they're doing well in (i.e., within the ABCs of SLEEPING mnemonic described above) and what areas they can improve on. The third component of this intervention are the sleep tips which are sleep recommendations that are customized based on the identified areas of sleep the parents are suggested to work on.
Study NCT05669846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fecal Microbiota Transplant (FMT)
Description: FMT is a procedure in which fecal matter or stool is collected from a tested donor, mixed with a saline or other solution, strained and infused into the colon by performing a colonoscopy and sigmoidoscopy. The FMT consists of introducing normal bacterial flora contained in the stool collected from a donor into the small intestine. In this case, the donors are patients with advanced metastatic non-small cell lung cancer (NSCLC) who have undergone PD-1 therapy (nivolumab or pembrolizumab) and are currently in a durable remission that is ongoing. The FMT will be performed on Cycle 1 Day 1 and Cycle 3 Day 1 during Treatment Phase 1 and every 9 weeks starting with Cycle 4 Day 1 during Treatment Phase 2.
Study NCT05669846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: Pembrolizumab, 200mg, will be administered as a 30-minute IV infusion every 3 weeks starting Cycle 1 Day 1 (same day as the FMT), and continue on Day 1 of each 21-day cycle.
Study NCT05252455 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: pelvic and abdominal mechanics exercise
Description: starting from 24 weeks of pregnancy, participate in the pelvic and abdominal mechanics exercises offered by the Good Pregnancy College of Shanghai Tongren Hospital once a week. Each class lasts one hour until the 38th week of pregnancy (attend at least 10 times)
Study NCT03624413 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social Media Intervention
Description: The social media intervention is a behavioral intervention developed by the study investigators and is delivered via mobile phones. The intervention uses the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) model, highlighting modifiable targets of intervention that can be addressed through a social media platform. The SMART model incorporates modifiable factors such as knowledge, skills/self-efficacy, relationships and social support that can be targets of interventions to improve transition care. The SMART model emphasizes eight modifiable factors, three key stakeholders (adolescents, caregivers, and clinicians) and their interconnected relationship in influencing successful transition to adult care. The intervention is designed to overcome barriers and enhance facilitators to transitioning care among adolescents living with HIV who are transitioning to adult care in South Africa.