AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06169761 — intervention group
Intervention type: OTHER
Intervention: Assessment of motor skills of the tongue and others muscles, see below) and risk for sleep apnea
Description: The following items will be assessed:~1. Risk for sleep apnea, through the STOP-BANG Questionnaire.~2. Anthropometric data: Height, weight, neck circumference, maximal mouth opening and maximal mouth opening with tongue to palate (with the Quick Tongue-Tie Assessment tool).~3. Tongue peak pressure (i.e., the maximal pressure - Pmax - exerted against the IOPI bulb in kPa) during 3 sec. of tongue protrusion and elevation.~4. Tongue endurance (i.e., the time to task failure in maintaining a pressure equal to a fixed percentage of Pmax against the IOPI bulb) during tongue protrusion and elevation~5. Tongue mobility restriction measured with the Quick Tongue-Tie Assessment Tool~6. Maximum inspiratory and expiratory pressures measured with MicroRPM in cmH2O~7. Handgrip strength (measured with a JAMAR dynamometer in kg)~Tongue skills measurements will be repeated 2 to 4 weeks after baseline to assess the reliability of these measurements.
Study NCT04848207 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Digital impression technique
Description: 3D printed generic Scan bodies with unified shape and length replacing the traditional transfer copings will be press fitted on the trans-mucosal abutments and pickup cylinders that are screwed on the implants to capture their position and intra-oral scanning will be done.
Study NCT04848207 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Open tray impression technique
Description: Transfer copings will be screwed to the multiunit abutments on the existing implants, and splinted together using pre-cured printed resin splinting framework that will be fixed to the copings using flowable composite .~A one step impression technique using putty and light addition silicon will be made, where light impression material will be injected all around transfer copings and putty silicon will be loaded in tray and then will be seated intra-orally making sure to fully expose the screws of transfer copings through the impression material.
Study NCT04842019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KRN23
Description: KRN23 is a sterile clear colourless and preservative free solution supplied in single use 5 mL vials containing 1 mL of KRN23 at a concentration of 30mg/mL
Study NCT05773352 — intervention group
Intervention type: DEVICE
Intervention: Tornier Perform® Humeral System - Fracture
Description: A replacement of shoulder joints for anatomic and reverse shoulder arthroplasty.~A replacement of other shoulder joints devices in case of revisions if sufficient bone stock remains.
Study NCT04853381 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment (low FODMAP)
Description: The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.
Study NCT04853381 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment (gluten free)
Description: The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.
Study NCT04853381 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment (low FODMAP+gluten free)
Description: The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.
Study NCT04853381 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dietary treatment (Traditional diet recommendations)
Description: The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.
Study NCT05616806 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iENDURE
Description: Two delivery modes: computer and text message. The intervention provides introductory strategies for managing physical and emotional distress associated with Long COVID through a computer-delivered session followed by 4-weeks of theoretically-informed text messages intended to promote distress tolerance (DT).~Computer - the initial intervention will be delivered online via the Qualtrics survey tool following informed consent. The intervention provides strategies to better tolerate emotional and physical discomfort to persist with behavioral goals. Text Message - The text message intervention will be delivered using Marigold Health (a HIPAA compliant platform for secure text messaging). Participants will receive daily text messages that focus on emphasizing adaptive strategies for tolerating physical and emotional discomfort in order to work toward behavioral goals. The text messages will be personalized and offer skills training (reminders of previously learned DT skills).
Study NCT04630639 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sparkle
Description: The Sparkle device is a single-use device intended to aid the diagnosis of sleep-disordered breathing; however, this study is intended only to validate the respiratory effort signal and does not assess diagnostic performance.
Study NCT05797480 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Real Dry needling
Description: Real dry needling will be applied to the pelvic floor, hip and lower back muscles.
Study NCT05797480 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Non penetrating dry needling
Description: Sham non penetrating dry needling (fixed needle in an introducer tube) will be applied to the pelvic floor, hip and lower back muscles.
Study NCT06246591 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Extracorporeal Shockwave Therapy (Group A)
Description: Each patient was evaluated before treatment for trigger points; patients underwent focal ESWT (PulseWave 2 - Mectronic Medicale s.r.l.) with a specific program for muscle contractures and myofascial pain (80-100 mJ with 2250 pulses of 5-10 Hz).
Study NCT06497634 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 25 PP
Description: Spinal anesthesia will be performed in sitting position, with 25 G pencil point needle (Whitacre -Egemen®) midline through the L4-5 or L5-S1 interspace, parallel to the dural fibers. Upon clear cerebrospinal fluid (CSF) detection, the needle apertures will be turned towards the cephalad direction, and 3 ml (15 mg) of 0.5% hyperbaric bupivacaine (Marcaine Heavy ®) will be injected into the intrathecal space.
Study NCT06497634 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 25 Q
Description: Spinal anesthesia will be performed in sitting position, with 25 G sharp edge needle (Quincke -Egemen®) midline through the L4-5 or L5-S1 interspace, parallel to the dural fibers. Upon clear cerebrospinal fluid (CSF) detection, the needle apertures will be turned towards the cephalad direction, and 3 ml (15 mg) of 0.5% hyperbaric bupivacaine (Marcaine Heavy ®) will be injected into the intrathecal space.
Study NCT06497634 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: 27 Q
Description: Spinal anesthesia will be performed in sitting position, with 27 G sharp edge needle (Quincke -Egemen®) midline through the L4-5 or L5-S1 interspace, parallel to the dural fibers. Upon clear cerebrospinal fluid (CSF) detection, the needle apertures will be turned towards the cephalad direction, and 3 ml (15 mg) of 0.5% hyperbaric bupivacaine (Marcaine Heavy ®) will be injected into the intrathecal space.
Study NCT06497634 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Optic Nerve Sheath Measurement
Description: Sonographic measurement of ONSD (EsaoteMyLabFive, Cenova, Italy) for all patients will be performed by a single experienced anesthesiologist. After a thin gel layer apply to the upper eyelid, the patient in the supine position and with the eyes closed, using a 6-13 MHz linear probe, optic sheath nerve measurement will be done 3 mm behind the optic globe, with a total of three measurements of which the final value will be recorded.The measurement will be repeated five times using US guidance at the following time points: T0 (pre-anesthesia), T1 (5 minutes after spinal block), T2 (15 minutes after spinal block, T3 (tourniquet opening), and T4 (24 hours after spinal block ) respectively.
Study NCT06246591 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mesotherapy (Group B)
Description: Each patient was evaluated before treatment for trigger points; after disinfection with Chlorhexidine 2% and sterile gauze, Thiocolchicoside fl 4mg/2ml, and a local anesthetic, Mepivacaine fl 10mg/1ml, diluted in 0.9% NaCl saline, for a final volume of 10 ml, were inoculated mesodermally; 6 to 12 microinjections with needle 26G 0.40x4mm, were performed.
Study NCT06385964 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-4597
Description: SHR-4597 by dry powder inhalation
Study NCT06385964 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo by dry powder inhalation
Study NCT05536960 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 68Ga-Dotatate PET/CT
Description: One 68Ga-Dotatate PET/CT to determine uptake of tracer in the arterial wall.
Study NCT04881188 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Survey
Description: Patients with chronic low back pain in in-patient multimodal pain therapy. Three survey times, questionnaires
Study NCT05991362 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GFH312 100 mg
Description: Participants receive single dose of GFH312 100 mg orally
Study NCT05991362 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GFH312 200 mg
Description: Participants receive single dose of GFH312 200 mg orally
Study NCT05991362 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GFH312 120mg
Description: Participants receive daily dose of GFH312 120mg orally for fourteen consecutive days
Study NCT05991362 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants receive placebo matching with GFH312
Study NCT05662605 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: W-PPMA
Description: W-PPMA is a digital health tool designed specifically for the postpartum experience and is accessed through a mobile application which delivers evidence-based therapy through brief conversations with a fully automated relational agent called Woebot.
Study NCT06468904 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: cervical stabilization exercises and integrated neuromuscular technique.
Description: Patients received cervical stabilization exercises and integrated neuromuscular inhibition technique. Cervical stabilization protocol included strengthening exercises of deep cervical flexors muscles which included chin tucks, isometric holds, ball squeeze, as well as deep cervical extensors muscles which included cranio-cervical flexion from neutral, upper cervical rotation and extension of cervical spine.~integrated technique includes ischemic compression, muscle energy technique and strain counter strain.
Study NCT06468904 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: cervical stabilization exercises and integrated neuromuscular technique.
Description: Patients received cervical stabilization exercises and integrated neuromuscular inhibition technique. Cervical stabilization protocol included strengthening exercises of deep cervical flexors muscles which included chin tucks, isometric holds, ball squeeze, as well as deep cervical extensors muscles which included cranio-cervical flexion from neutral, upper cervical rotation and extension of cervical spine.~integrated technique includes ischemic compression, muscle energy technique and strain counter strain.
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STELLA-R Curriculum
Description: The STELLA-R curriculum is presented utilizing the ABC analytic approach to address care recipient's distressing behaviors. Using the scaffold of the ABC pyramid, they will receive video instructions on how to fully define the Behaviors they want to address by observing, describing, and writing about them. The care partners will learn to identify the Activators, the triggers for the behaviors. Next, care partners will learn to consider what happens after the behaviors, the Consequences. This is an 8-week self-directed, online weekly curriculum.
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: STELLA-R Curriculum
Description: The STELLA-R curriculum is presented utilizing the ABC analytic approach to address care recipient's distressing behaviors. Using the scaffold of the ABC pyramid, they will receive video instructions on how to fully define the Behaviors they want to address by observing, describing, and writing about them. The care partners will learn to identify the Activators, the triggers for the behaviors. Next, care partners will learn to consider what happens after the behaviors, the Consequences. This is an 8-week self-directed, online weekly curriculum.
Study NCT06380387 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Meal
Description: Liquid meal
Study NCT04476277 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Biotin label
Description: Autologous cells will be collected and biotin-labeled ex vivo and reinfused to measure red cell survival
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Unrestricted Access
Description: Following the STELLA-R curriculum, care partners will receive 8 weeks of unrestricted access to all lessons and resources.
Study NCT05128136 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Impact of ring size on adherence
Description: The study design is a randomized, open-label, parallel group 3-way crossover study comparing adherence, preference and overall acceptability of 3 different-sized placebo IVRs (IVRs A, B and C) in 24 US couples. At enrollment, each couple will be randomly assigned to 1 of 6 sequences of IVR use: A-B-C, A-C-B, B-A-C, B-C-A, C-A-B or C-B-A. Each couple will use each of the 3 IVRs (IVRs A, B and C) for 30 days per IVR, 90 days total.
Study NCT04840927 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: E7386
Description: Regimen A: 40 milligram (mg) IR Oral Tablet.
Study NCT05485051 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 2% chlorhexidine digluconate solution with surface-active agents
Description: Bathing will be performed at least daily using 2% chlorhexidine digluconate solution with surface-active agents on all applicable bathing surfaces, which consists of the entire body surface of the patient except eyes, inner ear, oral mucosa, and areas of loss of skin continuity (such as burnt areas, pressure injuries, etc.); These areas will be bathed according to each center current practice.
Study NCT05485051 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual Baths
Description: Bathing will be performed at least daily using soap and water (performed according to the current practice in each center) on all applicable bathing surfaces, which consists of the entire body surface of the patient except eyes, inner ear, oral mucosa, and areas of loss of skin continuity (such as burnt areas, pressure injuries, etc.); These areas will be bathed according to each center current practice.
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Unrestricted Access
Description: Following the STELLA-R curriculum, care partners will receive 8 weeks of unrestricted access to all lessons and resources.
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Limited Access
Description: Experimental and Waitlist Control group will experience 8 consecutive weeks of limited access to the STELLA-R website and resources. Waitlist Control will experience this from Week 1 to Week 8 while the Experimental Group will reach this phase from Week 17 to Week 24.
Study NCT06460012 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Limited Access
Description: Experimental and Waitlist Control group will experience 8 consecutive weeks of limited access to the STELLA-R website and resources. Waitlist Control will experience this from Week 1 to Week 8 while the Experimental Group will reach this phase from Week 17 to Week 24.
Study NCT04798105 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Effects of tDCS of dlPFC on Probabilistic Selection Task
Description: Predictors of Probabilistic Selection Task Performance including anodal tDCS of dlPFC, eye blink rate, extraversion and impulsiveness
Study NCT04798105 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Effects of tDCS of dlPFC on Probabilistic Selection Task
Description: Predictors of Probabilistic Selection Task Performance including anodal tDCS of dlPFC, eye blink rate, extraversion and impulsiveness
Study NCT05414565 — intervention group
Intervention type: DEVICE
Intervention: Vivity IOL
Description: Commercially available extended vision IOL
Study NCT05414565 — intervention group
Intervention type: DEVICE
Intervention: Aspheric monofocal IOL
Description: Commercially available aspheric IOL
Study NCT05713305 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Online-based self-help psychological intervention
Description: Daily members of the intervention group were thought to provide three different forms of daily sessions each day, averaging 10-20 minutes. These sessions included psycho-educational and cognitive-behavioral exercises, music therapy, sleep hygiene, stress relief methods. Weekly online lecture sessions presented by professional mental health therapists
Study NCT05713305 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Provide online mental health knowledge
Description: They will receive official mental health recommendations on how to cope mentally with the pandemic. These recommendations inform about the importance of a daily structure, social contact, acceptance of negative emotions and strengthening of positive emotions, and stimulus control to assimilate SARS-CoV-2 Omicron-related news
Study NCT05228912 — intervention group
Intervention type: DRUG
Intervention: COVID-19 Vaccines
Description: Each group will receive a complete scheme of the vaccine according to local government assignation
Study NCT05646069 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Storz Flex-XC1 Disposable Flexible Ureteroscope
Description: Patients will receive flexible ureteroscopy with the Storz Flex-XC1 disposable flexible ureteroscope.
Study NCT05646069 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Storz Flexible Digital Ureteroscope
Description: Patients will receive flexible ureteroscopy with the Storz flexible Digital ureteroscope.
Study NCT05438485 — intervention group
Intervention type: OTHER
Intervention: Registry
Description: Observational (Registry)
Study NCT06671847 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: THERABand resistance exercise bands
Description: The training will be performed using THERABand resistance exercise bands.Participants will be instructed to perform the exercises twice per week at home, for the 24 weeks duration. Each exercise session will entail 1 set of 15 repetitions of 9 different exercises
Study NCT05847270 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior and posterior treatment strategy
Description: Before surgery, a large weight traction of 1/6 body weight was used to determine the reversibility of atlantoaxial dislocation. After determining that it is difficult to restore the dislocation, a technique of anterior oral release and posterior fixation fusion was used for reduction, with sequential release of the longus colli and longus capitis, the anterior longitudinal ligament, the blitateral lateral mass joints, the contracted soft-tissue mass between the odotiod and the anterior C1 tubercle, and the peri-odontoid ligaments (i.e., the alar ligaments and the apical ligament), followed by posterior internal fixation and bone grafting was used between C1 and C2 lamina.
Study NCT05847270 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Simple posterior approach treatment strategy
Description: Preceding the surgical procedure, an assessment was conducted utilizing 1/6 weight traction to ascertain the reducibility of atlantoaxial dislocation. Upon confirmation of IAAD, the chosen approach involved the utilization of a specially designed spreader, tailored to the patient's atlanto-axial joint morphology. Upon entering the joint space, the spreaders were skillfully maneuvered to gently open the joint through rotational and prying actions. Subsequently, two cages, pre-filled with autogenous bone grafts, and designed with the appropriate angle and height, were meticulously placed between the Atlanto-axial joints via a posterior approach. This procedure facilitated direct distraction and reduction of the dislocated joint. In the final step of the surgical process, stabilization was achieved by securing the atlas and axis with screws and rods. This surgical approach was selected to address the unique challenges posed by IAAD, with the aim of achieving optimal patient outcomes.
Study NCT06671275 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cell therapy
Description: Subjects were placed sequentially into three different dose groups, 5.0×107 cells/time (low-dose group), 1.5×108 cells/time (medium-dose group), and 5.0×108 cells/time (high-dose group) for dose escalation
Study NCT06671249 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Laparoscopic breast-conserving surgery
Description: Use laparoscopic surgery to treat breast cancer patients who want and have the opportunity to preserve their breast
Study NCT06671249 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Traditional open breast-conserving surgery
Description: Treat breast cancer patients who want and have the opportunity to preserve their breast with traditional open breast-conserving surgery.