AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04137653 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel+carboplatin
Description: Paclitaxel (Yangtze River Pharmaceutical Co., Ltd., Taizhou, Jiangsu Province, China; drug license No. Guoyao Zhunzi H20053001), 125 mg/m2, intravenous drip for 30 minutes once, on days 1 and 8, 21 days as a session for a total of 6 sessions; at the same time, carboplatin, AUC=2 mg•min/mL, intravenous infusion for 120 minutes once, on days 1 and 8, 21 days as a session for a total of 6 sessions.
Study NCT05093907 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BEY1107
Description: Administer once daily, PO, 3-week continuous dose.
Study NCT05093907 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Administer twice daily, PO, 2-week continuous dose, followed by 1-week rest period.
Study NCT05566431 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ICP
Description: The intervention is a management protocol that includes ICP monitoring for children with severe traumatic brain injury
Study NCT05566431 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CREVICE
Description: The intervention is a management protocol that is based on imaging and clinical examinations without ICP monitoring for children with severe traumatic brain injury
Study NCT04902404 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: First Pathways Game
Description: The First Pathways Game is a free, online parenting education program. Parents watch short videos (approximately 30 seconds) on the First Pathways Game website to receive neuroscience knowledge and ideas for age-appropriate game ideas to play with their child. The game ideas employ common household items, such as measuring cups and paper.
Study NCT04837989 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Diabetes Body Project
Description: Six virtually delivered Diabetes Body Project groups over six weeks (one hour a week); 5-6 participants and 2 group facilitators
Study NCT04837989 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychoeducation
Description: Individuals assigned to the psychoeducational control condition will receive an educational brochure, and complete similar assessments and assessment time points as the experimental condition. Individuals in the control group will be offered Diabetes Body Project group participation after six months.
Study NCT05973773 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAS6417
Description: oral tablets
Study NCT04872348 — intervention group
Intervention type: DEVICE
Intervention: OMNI® Surgical System
Description: The OMNI® Surgical System is indicated for canaloplasty (microcatheterization and transluminal viscodilation of Schlemm's canal) followed by trabeculotomy (cutting of trabecular meshwork) to reduce intraocular pressure in adult patients with primary open-angle glaucoma.
Study NCT05976763 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Computed Tomography
Description: Undergo CT
Study NCT05976763 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05976763 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic Resonance Imaging
Description: Undergo MRI
Study NCT05976763 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Esophagogastroduodenoscopy
Description: Undergo EGD
Study NCT06687148 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham manipulation
Description: The participants will receive one session of sham manipulation if in the sham group. For instance, to correct right anterior innominate rotation, the participant will be made to lie on the side so that the affected side is upward. The physiotherapist will stand in front of the participant; first we will put their shoulders, pelvis and lower limbs in neutral position and place the right hand on the anterior superior iliac spine (ASIS) and the left hand on the ischium tuberosity and with a rotational movement of the hands, the physiotherapist will rotate the ilium posteriorly. At the end of the range, we will replace the position of hands and place the left forearm on the ischium tuberosity and place the right hand on the upper participant's shoulder and will move it toward the bed at the end of the range in exhalation, the physiotherapist will pretend to execute a thrust.
Study NCT05976763 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Esophagogastroduodenoscopy
Description: Undergo EGD
Study NCT06697431 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anakinra
Description: Patients who fulfill the eligibility criteria a will be randomized 1:1 to receive either~1. IVIG 2g/kg administered in 10-12 hours as per local standard of care (standard treatment) OR~2. Anakinra 2mg/kg intravenously, max 100 mg/dose 4 times/day (investigational treatment)~Patients showing fever, between 36 hours and 72 hours from the end of first line treatment will be considered failures. Failures from the investigational treatment arm will receive a dose of IVIG and they will drop from the study.~Children who remained afebrile between the 36th and 72nd hour will be considered as responders, and they will proceed into the study.~Patients in the standard treatment arm will continue ancillary treatment and follow-up .~Patients in the investigational treatment arm will enter the tapering phase.
Study NCT06520852 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Group using artificial intelligence tools in addition to traditional tools in preparing educational materials
Description: Students in the intervention group used AI tools in addition to tools such as books, journals, and websites.
Study NCT06506227 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low risk experimental group
Description: Guiding + Manipulation + Traditional Chinese Medicine
Study NCT06506227 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Medium risk experimental group
Description: Guiding + Manipulation + Traditional Chinese Medicine + Specific Exercise Therapy + Orthopedic Braces
Study NCT06506227 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: High risk experimental group
Description: Guiding + Manipulation + Traditional Chinese Medicine + Specific Exercise Therapy + Orthopedic Braces + Specialized Inpatient Rehabilitation
Study NCT06506227 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control group COBB 10-20°
Description: Specific Exercise Therapy
Study NCT06506227 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control group COBB 20-45°
Description: Orthopedic Braces + Specific Exercise Therapy
Study NCT06506227 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Control group COBB >45°
Description: Orthopedic Braces + Specific Exercise Therapy + Recommended Surgery
Study NCT06506227 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental group (AIS group)
Description: Molecular marker exploration and validation
Study NCT06506227 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control group (healthy control)
Description: Molecular marker exploration and validation
Study NCT06506227 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Controlled follow-up before and after AIS
Description: Construction and validation of AIS risk prediction model completed
Study NCT05893173 — intervention group
Intervention type: BEHAVIORAL
Intervention: Sleep Deprivation
Description: Ten individuals (aged 18-85) with a DSM-V diagnosis of MDD will undergo baseline GluCEST imaging prior to and following approximately 30 hours of total sleep deprivation.
Study NCT06697431 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous Immunoglobulins, Human
Description: see previous section
Study NCT06699147 — intervention group
Intervention type: DEVICE
Intervention: Hyaluronic Acid (HA)
Description: 6 types of hyaluronic acid(HA) fillers that are differ in HA concentration and lidocaine were used for this study. Each type was applied to different condition or group depending on the investigators medical diagnosis
Study NCT05120297 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AK101
Description: Subjects will receive AK101 subcutaneous injection at week 0 and week 4, and will follow up to week 16.
Study NCT05120297 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subjects will receive placebo subcutaneous injection at week 0 and week 4, and will follow up to week 16.
Study NCT04924647 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lenalidomide and dexamethasone
Description: lenalidomide 25mg d1-21 and dexamethasone 20-40mg d1，8，15，22
Study NCT04432662 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Darbepoetin Alfa
Description: Administration of Darbepoetin Alpha (10 mcg/kg) IV x2 doses following cooling therapy.
Study NCT05193656 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Al_bladder
Description: Detection of bladder tumor with help of Artificial intelligence
Study NCT05778747 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Heart to Heart Yoga
Description: The Heart to Heart Yoga intervention is a therapeutic and standardized form of yoga intervention that is adapted from MediYoga designed to fit the needs of patients with HF and family caregivers who have physical limitations and depressive symptoms and to fit cultural and social norms in Kentucky. The intervention will use a gradual, physical/ psychological yoga adaptation approach, and it will be delivered two times per week (40 -60 minutes per session) via videoconference technology for 12 weeks (total 24 sessions). Real-time, face-to-face, video conferencing technology is used.
Study NCT06700122 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D
Description: non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D
Study NCT06700122 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D
Description: non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D
Study NCT06698484 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAR-T cells
Description: 2×10\^6 CAR T cells/kg
Study NCT05379517 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Pulsed ectromagnetid field therapy
Description: Pulsed electromagnetic field therapy is an innovative therapy. The technology is based on a high intensity electromagnetic field, which positively influences human tissue. It is a form of non-invasive treatment, with good tolerance by patients. High-intensity electromagnetic fields excite neural and muscle cells, which stimulates the human body.
Study NCT05379517 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary rehabilitation program (PRP)
Description: This type of physiotherapy program includes: respiratory muscle training, coughing exercises, diaphragmatic training, aerobic training and strength training.
Study NCT04284735 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Quantitative ATX and LPA determination in plasma and sputum
Description: Determination of ATX and LPA levels in plasma and sputum from RA-ILD patients (cases) and in plasma and sputum from RA patients without ILD (controls) after sputum induction using hypertonic saline inhalation
Study NCT06277986 — intervention group
Intervention type: OTHER
Intervention: cachexia
Description: Cachexia mainly manifests as weight loss. 1)weight loss >5% over past 6 months. 2)BMI\<20 and any degree of weight loss >2%. 3)Appendicular skeletal muscle index consistent with sarcopenia and any degree of weight loss >2%.
Study NCT06698666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rosuvastatin 10 mg tablet.
Description: The dose of rosuvastatin was derived from literature describing the doses at which the agents' targeted actions are effective and safe. The 10- mg rosuvastatin dose reflects the lowest prescribed therapeutic dose A serum cholesterol level will be drawn from the whole participants and sent to the central laboratories of El-Demerdash hospital at baseline and at week 12.~At each visit, participants will be requested to return all unused investigational products. Adherence to medication will be assessed by a pill count.
Study NCT06698666 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Sertraline Pill
Description: Both control and intervention group will receive the sertraline as a standard therapy
Study NCT06698666 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline Pill
Description: Both control and intervention group will receive the sertraline as a standard therapy
Study NCT06700161 — intervention group
Intervention type: OTHER
Intervention: Obtaining CGF from patients
Description: Periodontal clinical parameters and Annexin and Lipoxin parameters in CGF will be compared between the test and control groups
Study NCT06698393 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Suture 3.0 Group
Description: The extent of the depth of the recession will be reported on the anatomical papillae and, after adding 1 mm, 2 horizontal incisions of approximately 3 mm will be made at the base of the surgical papillae laterally to the recession.Two divergent releasing incisions will be made extending approximately 2-3 mm into the alveolar mucosa.The surgical papillae will be detached in partial thickness. A full thickness dissection will be performed from the bottom of the recession to expose approximately 3mm of the crest bone.A partial thickness dissection will be performed in the most apical portion of the flap until complete passivation of the flap is obtained.The harvesting of the epithelial-connective graft will be performed at the la. The de-epithelialised graft will be sutured at the level of the de-epithelialised anatomical papillae.The flap will be repositioned coronally suturing the anatomical papillae on the surgical ones, using a Non-Resorbable Polyamide Suture of 3.0 Diameter.
Study NCT06698393 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suture 6.0 Group
Description: The extent of the depth of the recession will be reported on the anatomical papillae and, after adding 1 mm, 2 horizontal incisions of approximately 3 mm will be made at the base of the surgical papillae laterally to the recession.Two divergent releasing incisions will be made extending approximately 2-3 mm into the alveolar mucosa.The surgical papillae will be detached in partial thickness. A full thickness dissection will be performed from the bottom of the recession to expose approximately 3mm of the crest bone.A partial thickness dissection will be performed in the most apical portion of the flap until complete passivation of the flap is obtained.The harvesting of the epithelial-connective graft will be performed at the la. The de-epithelialised graft will be sutured at the level of the de-epithelialised anatomical papillae.The flap will be repositioned coronally suturing the anatomical papillae on the surgical ones, using a Non-Resorbable Polyamide Suture of 6.0 Diameter.
Study NCT05629624 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Chickpea based RUSF
Description: One group will receive locally produced RUSF, approximate at 50-100 kcal/kg/day, two of 50g packets daily (42) until anthropometric recovery ( WHZ > - 1SD) has been achieved or for maximum 3 months then immediately 1 packet / day SQLNS will be given throughout the study till the end of 2 years of follow-up.
Study NCT05629624 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: E-RUSF
Description: The other group will receive the E-RUSF at 50-100 kcal/kg/day which in this age group approximates one 92 g sachet daily until anthropometric recovery ( WHZ > - 1SD) has been achieved or for a of maximum 3 months, then immediately E-SQLNS 1 packet daily provided throughout the study till the end of 2 years of follow-up.
Study NCT05629624 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Outcome reference group/RUSF
Description: We will also recruit 70 three-year-old previously untreated MAM children WHZ \<-2 and ≥-3 z-score, and/or MUAC \<12.5 and ≥11.5 cm as an outcome reference group for a singular assessment. All children (both case \& control) will undergo a baseline nutritional, medical, biological and neuropsychological assessment (EF, ER, EEG and fNIRS). After all the assessments chick-pea based RUSF will be given for 2 months for nutritional rehabilitation.
Study NCT05830201 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: No Dog Present
Description: Dog is not present during pin removal
Study NCT05830201 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Dog is Present
Description: Dog is present during pin removal
Study NCT05424042 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: In-Person Caloric Restriction
Description: 20% CR delivered in-person by dietitian/coach
Study NCT05424042 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Remote Caloric Restriction
Description: 20% reduction in caloric intake, meeting schedule, and physical activity goal delivered remotely.
Study NCT05424042 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time-restricted
Description: 8-hour TRE with ad libitum caloric intake. This group will undergo a 9-month dietary intervention targeting consumption of all daily caloric intake within an 8-hour window of time, with no restrictions on caloric intake.
Study NCT05160519 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Class IV Laser
Description: 30 participants will be irradiated with Class IV laser therapy over the left parasternal area to examine the efficacy of class IV laser on ejection fraction, Cardiac Biomarker and functional outcomes.~Device: Litecure LCT-1000C Class IV laser will be used in contact method over the left parasternal area in 2nd, 3rd intercostal space and apex. Dosage and Parameters for the irradiation will be calculated. Parameters: 1. Wavelength: 980nm, 2. Power/ Energy density: 6W/6J/cm2 3. Frequency: CW 4. Energy delivered at each spot: 360J 5. irradiation spots: 3 6. Irradiation time: 60 sec at each spot.~Both the patient and laser giver will use the laser protected eye wears to ensure standard practice for the laser.
Study NCT05160519 — intervention group
Intervention type: RADIATION
Group type: SHAM_COMPARATOR
Intervention: Sham Class IV Laser
Description: 30 participants in sham control group will be suppose to irradiate with Class IV laser therapy over the left parasternal area, but the radiation will not be delivered.~Device: Litecure LCT-1000C Class IV laser will be placed over the left parasternal area in 2nd, 3rd intercostal space and apex without switching on the instrument.~Both the patient and laser giver will use the laser protected eye wears to ensure standard practice for the laser.
Study NCT06024850 — intervention group
Intervention type: OTHER
Intervention: Datas collected
Description: Datas collected by medical record: medical data (weight, height, smoking status, history) and socio-demographic data (age, occupation, type of injury) information, assessment of knee function before surgery, at 6 months and 1 year after surgery, magnetic resonance imaging (MRI) and radiological imaging at 1 year after surgery, results of the Iso-kinetic Muscle Assessment Test at 1 year after surgery to objectively determine the recovery of muscle function~The data collected will be used to perform a statistical analysis to evaluate the factors predicting a good long-term post-surgical evolution
Study NCT05424666 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Harvesting method and Fat graft preparation method
Description: The procedure begins by identifying the areas where the fat will be collected Then the sample is collected by micro-incision using a fine suction cannula or during conventional liposuction. The fat cells are taken from an area of the body where there is a reserve (generally, in the abdomen, hips, knees, inner thighs, buttock) The collected fat cells are then subjected to a sterile centrifugation for a few minutes so as to separate the cells that will be injected (intact fat cells) from the elements that must not be injected (fat cells destroyed by the sample, non-fat cells such as than blood cells).~Injection of fat cells into the breasts The reinjection of fat (lipofilling) is performed using micro-cannulas allowing incisions of the order of 1-2 mm in different angles and in multiple directions so as to increase the contact area between the grafted cells and the recipient tissues allowing a good grip of the injection.
Study NCT06523478 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intratonsillar immunotherapy (ITIT)
Description: During injection, the operator needs to gently shake the injection bottle about 20 times, the drug must be mixed to ensure the consistency of allergen concentration, and carefully check the patient's name and concentration on the bottle. Allergy extracts should not be injected intravenously, so the syringe will be aspirated to avoid inadvertent intravascular injection. Before each injection, after inserting the needle into the selected tonsil, before injecting the dose, the investigator will slightly pull the plunger of the syringe. If blood returns from the syringe, the syringe, and its contents will be discarded. The other tonsil will be selected and a new syringe will be prepared.
Study NCT06523478 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Subcutaneous immunotherapy (SCIT)
Description: Injection requires shaking bottle 20x to mix drug for consistency. Verify patient name \& concentration. Use 1 ml skin test syringe for deep subcutaneous injection at 45° angle, 1 cm into outer upper arm. Lift skin folds for deeper injection, avoid subcutaneous, muscular or intravascular. Inject slowly, 1 min for 1 ml. Avoid shallow injections which may cause local side effects. Alternate between left \& right arm for 5 min after injection for compression.
Study NCT05098925 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biological testing
Description: Blood sampling, microcapillary sampling, temperature monitoring, saliva testing, EHI questionnaire