AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06548178 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: T-DXd
Description: T-DXd (5.4 mg/kg Q3W on Day 1) ×6 cycles.
Study NCT06548178 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: THP
Description: Docetaxel (75 mg/m2 Q3W on Day 1) concurrent with trastuzumab (8 mg/kg loading dose followed by 6 mg/kg Q3W on Day 1) and pertuzumab (840 mg loading dose followed by 420 mg Q3W on Day 1) × 6 cycles.
Study NCT05070819 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: pro-ANP
Description: pro-ANP samples and fluid status assessment with functional tests (Teboul test) will be used 8 times intraoperatively.
Study NCT04830774 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: ILR, PMK, ICD
Description: * Patients receive a newly implanted ILR, PMK, or ICD during COVID-19 hospitalization or within 30 days after hospital discharge and are followed by daily automated remote transmissions.~* Patients have a previously implanted ILR, PMK, or ICD and are followed by daily automated remote transmissions
Study NCT05677724 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: HBV DNA Sequencing
Description: Clinical surgical specimens were obtained, cleaned briefly and transported to the laboratory.~Single-cell suspension preparation and blood cell separation were performed, single-cell sorting suspension was prepared and put on the machine, sorting and library construction were performed, and mRNA sequencing adaptor was docked.~Single cell data analysis. Based on the findings of single cell analysis, functional verification tests of tumor immune microenvironment cell groups and functional changes of tumor cells were designed.
Study NCT05739955 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sani24
Description: 24-hour continuously acting quaternary ammonium salt disinfectant
Study NCT05739955 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard EPA-registered disinfectant
Description: Standard EPA-registered disinfectant
Study NCT05739955 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Routine Disinfection
Description: Routine disinfection at the study hospital
Study NCT05033860 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Read leaflets containing knowledge of COVID-19 and vaccination.
Description: Leaflets containing knowledge of COVID-19 and vaccination were distributed, and participants are asked to read the leaflets.
Study NCT06504043 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HST101
Description: Biological: HST101
Study NCT06298110 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Platelets Rich plasma of the same patient
Description: on the morning of surgery, 30 mL of venous blood will be drawn from the patient in anticoagulant-containing PRP tube for preparation of PRP solution. The drawn blood will be centrifuged at 1,200 rpm for 12 minutes to be separated into three layers: an upper layer that contains platelets and white blood cells, an intermediate thin layer (the buffy coat) that is rich in white blood cells, and a bottom layer that contains red blood cells. The upper and intermediate buffy layers will be transferred to an empty sterile tube. The plasma will be centrifuged again at 3,300 rpm for 7 minutes to help with the formation of soft pellets (erythrocytes and platelets) at the bottom of the tube. Pellets are homogenized in the lower third (5 mL) of the plasma to create the PRP. The prepared PRP solution will be transferred within sterile single use syringe (3cm) from the laboratory to the operation room, then applied and spread over the subcutaneous space before skin closure
Study NCT05715034 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Compassionate Care
Description: Single-session web-based program
Study NCT05715034 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Relaxing with Nature
Description: Single-session web-based program
Study NCT05388383 — intervention group
Intervention type: DEVICE
Intervention: Ti-robot
Description: Tianji ROBOT--Orthopedic surgery robot led by Beijing Jishuitan Hospital
Study NCT05312385 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Isoflurane
Description: Inhaled isoflurane administered by Sedaconda ACD-S
Study NCT05312385 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: Intravenous infusion of propofol
Study NCT06279052 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Phone interview
Description: Phone interview during which the experience of the transition to adulthood among adolescents and young adults with Prader Willi Syndrome will be retrieved
Study NCT05503368 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: surgical treatment of vitiligo using NCES
Description: NCES is the standard technique for surgical treatment of vitiligo, herein we compare the standard technique, to added autologous cellular micro-grafts and to follicle cell suspension
Study NCT05503368 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: surgical treatment of vitiligo using NCES
Description: NCES is the standard technique for surgical treatment of vitiligo, herein we compare the standard technique, to added autologous cellular micro-grafts and to follicle cell suspension
Study NCT04526444 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fitness tracker
Description: Fitness tracker Mi Smart Band 5 with the computational algorithm PAI
Study NCT04526444 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Online training
Description: Les Mills On Demand
Study NCT04526444 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peer support via social media
Description: Facebook group
Study NCT06290466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Low dose group
Description: 300 mg,single dose.
Study NCT06290466 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Low dose group
Description: 300 mg,single dose.
Study NCT06290466 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: High dose group
Description: 400 mg, single dose.
Study NCT06290466 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: High dose group
Description: 400 mg, single dose.
Study NCT04188067 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ACTIVE rTMS
Description: All study participants will receive one block of ACTIVE rTMS. Each block will consist of daily sessions of active rTMS delivered to the left dorsolateral prefrontal cortex over ten days (Monday through Friday).
Study NCT04188067 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SHAM rTMS
Description: All study participants will receive one block of SHAM rTMS. Each block will consist of daily sessions of SHAM rTMS delivered to the left dorsolateral prefrontal cortex over ten days (Monday through Friday).
Study NCT06482099 — intervention group
Intervention type: BIOLOGICAL
Intervention: RSVpreF vaccine
Description: Injection in the muscle, 1 dose 0.5mL
Study NCT05052255 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RVU120
Description: RVU120 will be administered as a single oral dose every other day over a 3 week treatment cycle until disease progression or unacceptable toxicity and an alternative daily dosing schedule will also be tested.
Study NCT05071300 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Eplontersen
Description: Eplontersen will be administered by SC injection.
Study NCT05111002 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lefamulin
Description: 600mg tablet orally twice daily
Study NCT05111002 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxycycline
Description: 100mg tablet orally twice daily
Study NCT06539338 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: INT2104
Description: INT2104 is a lentiviral vector delivering a transgene for a chimeric antigen receptor specific for CD20 (CAR20)
Study NCT05911243 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupressure Therapy
Description: Undergo auricular acupressure
Study NCT05911243 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Best Practice
Description: Receive usual care
Study NCT05466955 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Free eye glasses for un or under-corrected myopia
Description: All participants randomised to the intervention group will be provided with free eye glasses
Study NCT04819893 — intervention group
Intervention type: BIOLOGICAL
Intervention: Maternal blood sampling
Description: 5 mL sample of venous blood on arrival at the maternity ward in accordance with standard protocols
Study NCT04819893 — intervention group
Intervention type: BIOLOGICAL
Intervention: Umbilical cord blood sampling
Description: 0.5mL sample from the umbilical cord after childbirth standard protocols
Study NCT04819893 — intervention group
Intervention type: BIOLOGICAL
Intervention: Placenta sampling
Description: Sampling of 3 cotyledons by cutting across the thickness of the placenta
Study NCT04819893 — intervention group
Intervention type: OTHER
Intervention: Data collection
Description: Newborn, Maternal and Premature Retinopathy Screening Data Collection
Study NCT05182294 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AIRVO 2, the new asymmetric nasal cannula
Description: The AIRVO 2 is a humidifier with integrated flow generator that delivers warmed and humidified respiratory gases to spontaneously breathing patient through a variety of patient interfaces. This is an FDA-approved 510k device for use in hospitals and nursing homes. During HFNT, oxygen will be passed through a heated humidifier (AIRVO 2, Fisher and Paykel Healthcare) and applied continuously through conventional large-bore binasal symmetric prongs or the new asymmetric prongs cannula device, with a gas flow rate of 20-35 liters per minute or as high as the patient will tolerate and an FiO2 to keep SaO2 ≥ 90% (Airvo 2, Fisher and Paykel Healthcare). Gas flow temperature will be adjusted based on patient's comfort and range from 34-37 degrees centigrade. After completion of the study, patients will be switched back to oxygen therapy administered by nasal prongs or mask..
Study NCT05247515 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Endoscopic mucosal resection with nexpowder
Description: At the end of the EMR procedure, the patient will be randomized. In the treated group, Nexpowder will be sprayed thanks to a catheter inserted through the operating channel of the endoscope.
Study NCT05093244 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SeQuent Please ReX
Description: The SeQuent Please ReX is a conventional rapid exchange balloon tip catheter with a drug-coated balloon (DCB). The surface of the SeQuent Please ReX balloon is coated with paclitaxel, embedded in a soluble matrix (resveratrol).
Study NCT05093244 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Plain old balloon angioplasty (POBA)
Description: Any commercially available semi-compliant PTCA balloon may be used per the investigator's discretion.
Study NCT06305923 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: colostrum cream
Description: the intervention in our study is everyday using a cream with active ingridient
Study NCT06305923 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo cream
Description: using a placebo cream
Study NCT06375811 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Elagolix 200 MG
Description: Elagolix tablet
Study NCT06375811 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Placebo or SOC IVF
Description: Sugar pill manufactured to mimic Elagolix 200mg
Study NCT05932654 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BSI-045B
Description: Patients will be treated with BSI-045B.
Study NCT05851534 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Preoperative optimisation program
Description: Preoperative screening of all patients scheduled for pancreatic resection on (aerobic) fitness level, malnutrition risk, psychological resilience, haemoglobin, iron and HbA1c concentration, frailty, and alcohol and smoking behaviour. All patients are provided with a patient-tailored, multimodal prehabilitation program, in which these potentially (partly) modifiable factors are preoperatively addressed
Study NCT05805696 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Impostor tasks
Description: Tasks to do every week
Study NCT05810571 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: preoperative remifentanil consumption
Description: continuous remifentanil infusion will applied for peroperative analgesia
Study NCT05810571 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: preoperative remifentanil consumption
Description: continuous remifentanil infusion will applied for peroperative analgesia
Study NCT05810571 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: postopeartive controlled anlagesia with morphine
Description: postoperative morphine patient controlled analgesia will be applied for postoperative analgesia
Study NCT05810571 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: postopeartive controlled anlagesia with morphine
Description: postoperative morphine patient controlled analgesia will be applied for postoperative analgesia
Study NCT06659055 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: DXA Imaging
Description: DXA imaging: lumbar spine, bi-lateral femoral necks
Study NCT06659055 — intervention group
Intervention type: RADIATION
Group type: OTHER
Intervention: EOSedge imaging
Description: Full body or full spine image
Study NCT06658860 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Modified Socket Shield Technique
Description: The modified socket shield technique involves partial retention of the buccal aspect of the tooth root during extraction to preserve the surrounding alveolar bone and soft tissue. This technique is used to optimize the condition for delayed implant placement by preventing resorption of the alveolar ridge.
Study NCT06658860 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional Tooth Extraction
Description: Conventional tooth extraction involves the complete removal of the tooth without the use of the socket shield technique. This arm served as the control group, with alveolar ridge changes observed and compared with those in the experimental arm over time.
Study NCT06660043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical activity
Description: 40 min circuit training session
Study NCT06660043 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: analgesic physical therapy
Description: physical therapy with massage and Transcutaneous Electrical Nerve Stimulation in a 40min session
Study NCT06660043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: analgesic physical therapy AND physical activity
Description: 25 min circuit training session and 15 min physical therapy
Study NCT06660056 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Recurrent or Progressive Gliomas of the Brain
Description: Use of Ommaya capsules
Study NCT06660329 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Janus Kinase Inhibitor
Description: Tofacitinib is used according to weight: 5\~\<7kg，2mg；7\~\<10kg，2.5mg；10\~\<15kg，3mg；15\~\<25kg，3.5mg；25\~\<40kg，4mg；≥40kg，5mg. All is twice a day.
Study NCT06658691 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multidisciplinary approach
Description: The study investigated a multidisciplinary approach consisting of an endocrinologist, a diabetes specialized nurse, and a clinical pharmacist to assess and improve diabetic foot care by systematic screening, patients' risk categorization, therapy optimization, and tailored education.~Risk of Diabetic Foot Ulcer (DFU) occurrence was assessed and evaluated by the endocrinologist, and the nurse based on the 2019 International Working Group on Diabetes Mellitus (IWGDF). At that point, only the clinical pharmacist knew about patients' allocations.~According to risk stratification, the clinical pharmacist provided intervention patients with educational sessions and tailored materials during scheduled three months follow-up interviews at Jordan University Hospital (JUH) DFU-related clinics.~Moreover, the study evaluated the impacts of the multidisciplinary approach on health-related Quality of Life (QoL) at baseline and at the end of the study. Economic impacts were also further analyzed.
Study NCT06660017 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Patients in this arm will receive unmedicated syrup solution dispensed as 20mg/5ml 4 times a day in addition to receiving one of the following standard treatments; Magic Mouthwash, saliva substitute rinses, over-the-counter remedies including honey or salt and soda rinses, non-steroidal anti-inflammatory drugs (NSAIDS), or opioid medications.
Study NCT06660017 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine Topical
Description: Patients in this arm will receive ketamine oral rinse dispensed as 20mg/5ml 4 times a day in addition to receiving one of the following standard treatments; Magic Mouthwash, saliva substitute rinses, over-the-counter remedies including honey or salt and soda rinses, non-steroidal anti-inflammatory drugs (NSAIDS), or opioid medications.
Study NCT05014763 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: connective tissue graft
Description: Connective tissue graft surgery will be done for increasing soft tissue volume. In this methods connective tissue will be harvested from lateral palate or tuberosity area.
Study NCT05014763 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: connective tissue graft
Description: Connective tissue graft surgery will be done for increasing soft tissue volume. In this methods connective tissue will be harvested from lateral palate or tuberosity area.
Study NCT06484842 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The combined psychological resilience and self-efficacy intervention
Description: Based on the content of the literature analysis and the group's previous research, a joint intervention programme on psychological resilience and self-efficacy for patients undergoing surgery for oesophageal cancer has been developed. The programme consists of 6 sessions in total, including preoperative period and one month after discharge, covering the period when patients' postoperative symptoms occur most severely. The intervention will be conducted in an individual, offline face-to-face format during the patients' hospital stay; considering the smooth implementation of the intervention after the patient will be discharged from the hospital, we will conduct the intervention in an individual, offline face-to-face format during the patient's outpatient review, and set up a WeChat group in case the patients are at home to conduct the intervention in the form of an online punch card.
Study NCT05911243 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Best Practice
Description: Receive usual care
Study NCT05911243 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT06484842 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The mindfulness intervention
Description: The oesophageal cancer surgery patients in the single intervention group will receive 5 sessions of mindfulness intervention consistent with the mindfulness intervention component of the combined intervention programme. The intervention will be conducted in an individual, offline face-to-face format during the patients' hospitalisation; we will conduct the intervention in an individual, offline face-to-face format during the patients' outpatient review, and set up a WeChat group in case the patients are at home in the form of an online punch card. Each session will include a pre-session reflection and post-session homework. The whole process will be supervised and reminded by interventionists, who will respond to patients' questions in a timely manner to ensure patients safety and the smooth implementation of the intervention. Adjustments and improvements will be made at any time according to the needs of patients undergoing oesophageal cancer surgery.
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bosutinib Monohydrate
Description: Given PO
Study NCT06245395 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Virtual Reality
Description: Meta Quest 2 Headset
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Decitabine
Description: Given IV
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enasidenib Mesylate
Description: Given IV
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gilteritinib Fumarate
Description: Given PO
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Glasdegib Maleate
Description: Given PO
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ivosidenib
Description: Given PO
Study NCT04655391 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Given PO
Study NCT05911243 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT05911243 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies