AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06347081 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Nd- YAG laser at 532nm wavelength
Description: Nd-YAG laser at 532nm wavelength every 2 weeks for 14 sessions. patients will also receive standard medical care, nursing, physiotherapy
Study NCT06125821 — intervention group
Intervention type: OTHER
Intervention: questionnaire
Description: questionnaire
Study NCT05954481 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Stress echocardiography
Description: After a rest trans thoracic echocardiography (usual follow-up), eligible patients will have a stress ultrasound echocardiography on a dedicated cycle ergometer
Study NCT05713032 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulsed radiofrequency on lumbar dorsal root ganglion
Description: voltage of pulsed radiofrequency on DRG
Study NCT05154448 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Non-Invasive Thermal Ablation of the Medial Branch Nerves (Neurolyser XR)
Description: Thermal ablation of the medial nerve branch using High Intensity Focused Ultrasound
Study NCT05154448 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham procedure
Description: Sham procedure done in an identical manner to the treatment arm, but without deploying acoustical energy
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: smart soup
Description: Severe AD, mild or moderate AD and MCI will be given smart soup
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Donepezil
Description: Severe AD and mild or moderate AD will be given donepezil
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Donepezil
Description: Severe AD and mild or moderate AD will be given donepezil
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Memantine
Description: Severe AD will be given memantine
Study NCT05755880 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intrathecal dexamethason
Description: After general anesthesia intrathecal dexamthasone will be added
Study NCT04618211 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Deucrictibant
Description: deucrictibant soft capsules for oral use
Study NCT04618211 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Placebo
Description: Matching placebo capsules for oral use
Study NCT06132373 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer delivered problem solving therapy
Description: PST uses a straightforward approach amenable to use in new settings given its focus on idiographic problems, therefore session content is driven by the adolescent's presenting problem causing the most distress or impairment. We will use the standardized, core steps of PST and existing manualized protocols including from the Friendship Bench study and the WHO protocol for Problem Management Plus. The peers will deliver PST through 5 structured counseling sessions of 30-60 minutes over a 4-6 week period. There are 5 core components of PST which including problem listing and identification, problem exploration, developing an action plan, implementation, and follow up. The components will be introduced in the first session and be reviewed in an iterative process across the session to help participants use this model for different problems.
Study NCT05190445 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel
Description: HER2/4-1BB
Study NCT05190445 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cinrebafusp alfa (PRS-343) in combination with tucatinib
Description: HER2/4-1BB
Study NCT05405816 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: laparoscopic sleeve gastrectomy
Description: laparoscopic sleeve gastrectomy for obesity
Study NCT06528379 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical Activity
Description: The exercise programme is a 6-month progressive tailored-based exercise regime comprising~* aerobic exercises (40-60%)~* resistance exercises (20-40%)~* balance with resistance exercises (20%) .~This is peformed 3 times weekly, it is tailored to each individual but delivered in a small group-based manner. Two sessions are supervised by physiotherapist /exercise scientist and one session is unsupervised, home-based.
Study NCT05132621 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Smear
Description: A smear of the posterior vaginal fornix collected with a gynecological speculum.
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Memantine
Description: Severe AD will be given memantine
Study NCT05538507 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Placebo
Description: patients with MCI will be given placebo
Study NCT05417932 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SCG101
Description: Infusion of HBsAg-specific TCR autologous T cells at assigned dose levels.
Study NCT05307653 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Penile block
Description: Penile block was performed in supine position. The penis was retracted caudally and then fixed with a leucoplast. After identifying the symphysis pubis (SP), a 22-gauge needle was inserted vertically about 1 cm lateral to the SP, and bupivacaine 0.5% (0.1 ml/kg, maximum 2.5 ml) was injected on each side after penetrating the Scarpa's fascia.
Study NCT05521581 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Hand massage
Description: Hand massage will be applied to primiparous mothers who gave birth by cesarean section and its effect on pain, comfort and gas release times will be evaluated.
Study NCT05870384 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Group Interpersonal Psychotherapy
Description: Ten sessions of IPT-G, which focuses on the common problem area of patient relatives, will be applied.
Study NCT05307653 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Erector spinea plain block
Description: Ultrasound guided ESPB was performed in prone position by Philips © (CX50 Extreme edition). The superficial probe was placed longitudinally at the midline just above the sacrum, and both erector spinae muscles and median sacral crests were identified. Using the in-plane approach, a 22-gauge needle was inserted in a craniocaudal direction till reaching the tip of the fourth median sacral crest. After negative aspiration to avoid intravascular or intrathecal puncture, bupivacaine 0.25% (1 ml/kg, maximum 20 ml) was administered.
Study NCT05091307 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad26.COV2.S
Description: Ad26.COV2.S will be administered as an IM injection.
Study NCT05091307 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Ad26.COV2.S
Description: Ad26.COV2.S will be administered as an IM injection.
Study NCT05091307 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Placebo will be administered as an IM injection.
Study NCT05091307 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered as an IM injection.
Study NCT05091307 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Influenza Vaccine
Description: Influenza vaccine high and standard dose will be administered as IM injection.
Study NCT05091307 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Influenza Vaccine
Description: Influenza vaccine high and standard dose will be administered as IM injection.
Study NCT06225089 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: pericapsuler nerve block
Description: -Ultrasound Guided pericapsuler nerve block: will be externally rotated and abducted to 45 degrees. The shoulder area will be sterilized with povidone-iodine. High-frequency linear ultrasound perpendicularly between the coracoid and the humeral head probe. The deltoid muscle, subscapular muscle and tendon, and humeral head will be identified on the ultrasound screen. With the in-plane technique, a 22 gauge, 50 millimeter (mm) simplex A peripheral nerve block needle will be used. After passing the deltoid muscle, the needle will contact the tendon of the subscapularis muscle. The needle will be slightly withdrawn and directed between the deltoid muscle and the tendon of the subscapularis muscle and a local injection consisting of will be applied.
Study NCT06502288 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 625 mg of amoxicillin with combined clavulanic acid tablet
Description: The intervention group must take 625 mg of amoxicillin with combined clavulanic acid tablets three times a day after meals for 7 days following extraction.
Study NCT05697042 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MY-Skills for Long COVID
Description: 8 week online intervention with therapeutic yoga and self-management education
Study NCT05371600 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Midazolam
Description: midazolam IV at 0.04 mg/kg
Study NCT05371600 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: an equal volume of saline IV
Study NCT05307653 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caudal block
Description: Caudal block was performed in the left lateral position. A 22 G needle was inserted through the sacral hiatus. The loss of resistance method was used to pass through the sacrococcygeal membrane and enter the caudal epidural space. Negative aspiration was then performed. When no blood or cerebrospinal fluid was observed, bupivacaine 0.25% (1 ml/kg, maximum 20 ml) was administered. The patient was returned to the supine position after the procedure was completed.
Study NCT05494346 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Measurement of peak nasal flow.
Description: Peak nasal flow measurements will be performed before and after the first use of the spray at D0, as well as after the use of the spray at the medical office at D3 (only for arm A).
Study NCT06473571 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Intervention Protocol (The 3GT)
Description: Participants will be asked to identify three things that went well that day and their role for this occurring \[What went well today, and what was your role in making it happen? as adapted from (Sexton \& Adair, 2019)\]. They will be asked to engage in this exercise for 15 days during the evening.
Study NCT06473571 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Group
Description: Participants will be asked to reflect on early memories of their life, with no specific prompts provided, for 15 days during the evening. This activity is consistent with prior efficacy studies of 3GT (Seligman et al., 2005).
Study NCT06426511 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab+Chemotherapy
Description: After surgical resection, patients received 4 cycle of toripalimab (240 mg) in combination with platinum-based adjuvant treatment. Administration of standard postoperative adjuvant chemotherapy for stage IB disease was not mandatory; decisions about whether patients with IB disease would receive adjuvant chemotherapy were made by the physicians.
Study NCT06426511 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Toripalimab+Chemotherapy followed by consolidation toripalimab
Description: After surgical resection, patients received 4 cycle of toripalimab (240 mg) in combination with platinum-based adjuvant treatment, and then maintenance treatment with single-agent toripalimab (240 mg) once every 3 weeks for up to 13 cycles.~Administration of standard postoperative adjuvant chemotherapy for stage IB disease was not mandatory; decisions about whether patients with IB disease would receive adjuvant chemotherapy were made by the physicians.
Study NCT05172843 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Surgical knee arthroplasty
Description: Surgery will be performed 3 months from inclusion in the trial (at week 13). The procedure and type of prosthesis and postoperative program will be at the discretion of the involved surgeon and the participating department.~Post-surgical care and rehabilitation will follow current clinical standards.
Study NCT05172843 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Supervised weight loss
Description: The supervised intensive dietary weight loss program will be initiated 3 months from inclusion in the trial (at week 13) and lasts for 12 weeks.~The program includes full meal replacement by a standard liquid energy intake in a supervised dietary program. Participants will attend the nutrition department weekly. They will be weighed on a decimal scale, given nutritional and dietetic instructions by an experienced dietitian and formula diet products are handed in sessions of 1-2 h. The participants will be taught to make diet plans.~Following the 12 weeks intensive dietary weight loss program participants will be scheduled for two booster follow-up sessions with a dietician at weeks 39 and 51.
Study NCT05200676 — intervention group
Intervention type: DEVICE
Intervention: SmartPill
Description: SmartPill is swallowed and passes through the digestive system while sending information to a recording device. The pill is passed in the stool and not reused.
Study NCT05490576 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: [18F] PI-2620 Tau Ligand
Description: Tau binding ligand
Study NCT04872595 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Personalized rATG (P-rATG)
Description: P-rATG days (always starting on Day -12 to -10)
Study NCT04872595 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Hyper fractionated total body irradiation
Description: (1375 - 1500cGy\*) Day -9 to -6~\*TBI dose in 125cGy fractions (with lung shielding) and total dose to be determined by treating physician/radiation oncology and is based off age, stage of disease, and anesthesia requirements.
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thiotepa
Description: (5mg/kg/day x 2 day) Day -5 to -4
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: (60mg/kg/day x 2 days) Day -3 to -2
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GCSF
Description: Day +7
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Busulfan
Description: Day -9 to -7 doses 2-3 to be adjusted per PK for target cumulative exposure of 65 mg\*h/L
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Melphalan
Description: (70mg/m2/day x 2 days) Day -6 to -5
Study NCT04872595 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: (25mg/m2/day x 5 days) Day -6 to -2
Study NCT05642702 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peptide complexed HA Age Defying Gel with Vitamin C & Niacinamide
Description: Semi Solid, Hydrophilic - Gel, A 0.04 mL of test sample will be dispensed onto the center of an appropriately sized filter paper will be placed in the designated IQ/Finn chambers prefixed to a micropore tape.
Study NCT05642702 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peptide complexed HA Age Defying Gel with Natural Extracts
Description: Semi Solid, Hydrophilic - Gel, A 0.04 mL of test sample will be dispensed onto the center of an appropriately sized filter paper will be placed in the designated IQ/Finn chambers prefixed to a micropore tape.
Study NCT05642702 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peptide complexed HA Age Defying Gel with Vitamin C & Natural Extracts
Description: Semi Solid, Hydrophilic - Gel, A 0.04 mL of test sample will be dispensed onto the center of an appropriately sized filter paper will be placed in the designated IQ/Finn chambers prefixed to a micropore tape.
Study NCT05642702 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 1% w/v Sodium Lauryl Sulphate (SLS) solution
Description: 1g of Sodium Lauryl Sulphate will be dissolved in distilled water and made up to 100 mL solution using distilled water. A 0.04 mL of test sample will be dispensed onto the center of an appropriately sized filter paper will be placed in the designated IQ/Finn chambers prefixed to a micropore tape.
Study NCT05642702 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sodium chloride (Isotonic Saline Solution) Injection IP 0.9 % w/v
Description: A 0.04 mL of 0.9% w/v solution of Isotonic Saline Solution will be dispensed on the center of an appropriately sized filter paper, which will be further placed in the designated IQ/Finn chambers prefixed to a micropore tape.
Study NCT05426070 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Strength training-based exercise
Description: Participants will take part in two group-based Zoom exercise sessions and two individual exercise sessions per week for three months. Exercise sessions will include a combination of various aerobic (e.g., jogging in place, high knees) and muscle strengthening exercises (e.g., burpees, push-ups, lunges, body weight squats) designed to keep heart rate in the 60-85% range of maximum heart rate. Participants will choose from a variety of options for their two individual sessions (e.g., online exercise video, jogging or walking outside, prescribed exercise session listed on the website, or any other exercise) and modifications for each exercise will be made depending on the participant's ability and current fitness and strength level. Participants will be instructed to stop exercising if problems occur and will receive training and handouts on how to recognize problems such as angina and myocardial infarction.
Study NCT04770038 — intervention group
Intervention type: BEHAVIORAL
Intervention: Dialectical Behavior Therapy (DBT)
Description: Evidence-based psychotherapy for the treatment of Borderline Personality Disorder
Study NCT05719363 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Inogen Rove 6 Portable Oxygen Concentrator
Description: The Inogen Rove 6 POC is designed to provide a flow of high-purity oxygen. Inogen Rove 6 is a highly versatile and robust concentrator which offers patients the option to use up to 6 different flow settings.~The unit weighs just under 5 pounds. Utilizing an Intelligent delivery technology, the unit can provide patients with required oxygen therapy on a 24/7 basis. The Inogen Rove 6 POC will be used for patients with chronic heart failure as an investigational device. It supplies a high concentration of oxygen and is used with a nasal cannula which channels oxygen from the concentrator to the patient.
Study NCT05719363 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inogen Rove 6 Portable Oxygen Concentrator
Description: The Inogen Rove 6 POC is designed to provide a flow of high-purity oxygen. Inogen Rove 6 is a highly versatile and robust concentrator which offers patients the option to use up to 6 different flow settings.~The unit weighs just under 5 pounds. Utilizing an Intelligent delivery technology, the unit can provide patients with required oxygen therapy on a 24/7 basis. The Inogen Rove 6 POC will be used for patients with chronic heart failure as an investigational device. It supplies a high concentration of oxygen and is used with a nasal cannula which channels oxygen from the concentrator to the patient.
Study NCT06034509 — intervention group
Intervention type: OTHER
Intervention: No intervention. This is an observational study.
Description: There are no interventions being tested in the Cognitive and Vascular Functioning Following TBI study.
Study NCT06311890 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: N-chlorin e6 triglumine
Description: a photodynamic therapy with chlorin-e6
Study NCT06311890 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: acne removal surgery
Description: acne removal surgery will be given before red light exposure
Study NCT06311890 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: acne removal surgery
Description: acne removal surgery will be given before red light exposure
Study NCT05595993 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cilostazol
Description: Study participants will be allocated to receive oral administration of 200 mg cilostazol.
Study NCT05595993 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants will be allocated to receive oral administration of placebo.
Study NCT05357222 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Straw phontion
Description: Pitch Glides: (1 minute) Vocalize through the straw starting from as low as possible to as high as possible. As the participant you will want to get as much as your vocal range as possible. But, don't let the voice get growly at the bottom or press it into a painful range at the top.~2. Accents: (1 minute) Vocalize progressive little hills or accents. It sounds like a revving engine of the car.~3. Song: (1 minute) Pick a favorite song and vocalize it through the straw. Examples: National Anthem, Happy Birthday, Mary had a Little Lamb. These are great songs because they have a range of pitches and one can build some accents in, as well.~4. Reading passage: (1 minute) Vocalize a reading passage through the straw. Be as dramatic as possible, using a lot of inflection.
Study NCT06409143 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HD-tES
Description: The intensity of HD-tES is set at 2 mA, the current intensity ramps up to 2 mA within 5 seconds, remains at 2 mA for 10 minutes, and then ramps down to zero within 5 seconds. For the sham stimulation, the current intensity ramps up and down at the first and last 10 seconds, with the remaining 10 minutes set at 0 mA. The inhibitory and excitatory waveform will be selected based on results of sub-project 1.