AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05901545 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intraoperative Imaging
Description: Undergo Intraoperative Imaging
Study NCT05901545 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Near Infrared Imaging
Description: Undergo Near Infrared Imaging
Study NCT05901545 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Electrocardiography
Description: Undergo Electrocardiography
Study NCT05901545 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo blood sample collection
Study NCT06568562 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: XL092
Description: XL092 will be supplied as a tablet that will be taken at home once a day. Participants should drink at least 8 ounces of water with each dose of XL092. Participants should not eat at least 2 hours before taking the dose and 1 hour after. Participants will be given enough XL092 to take at home for a full cycle.
Study NCT05000957 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Laser Treatment
Description: Laser radiation is emitted by a series of pulses following each other through a pause. The duration of one pulse is 20-200 ns, the pause between pulses is 30 us. The energy of one pulse is about 1.5 mJ.~General laser radiation parameters for 1st and 2nd stages are: beam with diameter of 4 millimeters (mm) scans treatment area by 4 circles with step of 2 mm (50 percentage (%) overlap), average power of 10-25 Watt (W), treatment time in one point of 1-10 seconds (s), treatment step of 5 mm, from 1 to 5 repetitions of total vagina treatment. General laser radiation parameters for 3d stage are: beam diameter of 6 mm, average power of 15-30 W, duration of ns-pulses packet of 50-100 milliseconds (ms), pause between packets of 50-100 ms, treatment duration up to 65 s, treatment in permanent motion with speed of 10-50 mm/s.~The procedure is performed without anesthesia. The doctor always focuses on the participant's feeling of warmth.
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood analysis
Description: Taking blood from a vein for clinical blood analysis, glucose test, hepatitis B, C viruses, human immunodeficiency viruses and syphilis test, blood clotting tests, blood type and rhesus factor determination (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood analysis
Description: Taking blood from a vein for clinical blood analysis, glucose test, hepatitis B, C viruses, human immunodeficiency viruses and syphilis test, blood clotting tests, blood type and rhesus factor determination (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Blood analysis
Description: Taking blood from a vein for clinical blood analysis, glucose test, hepatitis B, C viruses, human immunodeficiency viruses and syphilis test, blood clotting tests, blood type and rhesus factor determination (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Сlinical urine test
Description: Urine sampling for Clinical urine test (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Сlinical urine test
Description: Urine sampling for Clinical urine test (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Сlinical urine test
Description: Urine sampling for Clinical urine test (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Electrocardiography
Description: Electrocardiography investigation to determine cardiac abnormalities (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Electrocardiography
Description: Electrocardiography investigation to determine cardiac abnormalities (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Electrocardiography
Description: Electrocardiography investigation to determine cardiac abnormalities (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Vaginal smear
Description: Vaginal smear for flora investigation, oncocytology (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal smear
Description: Vaginal smear for flora investigation, oncocytology (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Vaginal smear
Description: Vaginal smear for flora investigation, oncocytology (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Colposcopy
Description: Colposcopy investigation to determine pre-malignant and malignant lesions of cervix, vagina or vulva (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Colposcopy
Description: Colposcopy investigation to determine pre-malignant and malignant lesions of cervix, vagina or vulva (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Colposcopy
Description: Colposcopy investigation to determine pre-malignant and malignant lesions of cervix, vagina or vulva (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pelvic ultrasound
Description: Pelvic ultrasound investigation to determine pathologies of the pelvic through a gynecological probe (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic ultrasound
Description: Pelvic ultrasound investigation to determine pathologies of the pelvic through a gynecological probe (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Pelvic ultrasound
Description: Pelvic ultrasound investigation to determine pathologies of the pelvic through a gynecological probe (to include the participant in the study).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Doppler ultrasonography
Description: Ultrasound investigation for assessing blood flow in the tissues of vulva region (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Doppler ultrasonography
Description: Ultrasound investigation for assessing blood flow in the tissues of vulva region (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Doppler ultrasonography
Description: Ultrasound investigation for assessing blood flow in the tissues of vulva region (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. Potential of hydrogen (pH) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. Potential of hydrogen (pH) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Vaginal Health Index
Description: Vaginal Health Index will be investigated by clinical examination for vaginal elasticity, vaginal secretions, epithelial mucous membrane, vaginal hydration. Potential of hydrogen (pH) will be investigated by test-lines paper (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Biopsy of the vaginal wall
Description: Sampling of the vaginal wall material in the posterior fornix area including the mucous membrane and muscle layer will be performed during colporrhaphy or any pelvic surgical procedure for histological, immunohistochemical studies, and optical coherence tomography (elastography) (to evaluate procedure efficiency)
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Biopsy of the vaginal wall
Description: Sampling of the vaginal wall material in the posterior fornix area including the mucous membrane and muscle layer will be performed during colporrhaphy or any pelvic surgical procedure for histological, immunohistochemical studies, and optical coherence tomography (elastography) (to evaluate procedure efficiency)
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Biopsy of the vaginal wall
Description: Sampling of the vaginal wall material in the posterior fornix area including the mucous membrane and muscle layer will be performed during colporrhaphy or any pelvic surgical procedure for histological, immunohistochemical studies, and optical coherence tomography (elastography) (to evaluate procedure efficiency)
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire
Description: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire
Description: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire
Description: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pelvic Floor Distress Inventory Questionnaire
Description: Pelvic Floor Distress Inventory Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic Floor Distress Inventory Questionnaire
Description: Pelvic Floor Distress Inventory Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Pelvic Floor Distress Inventory Questionnaire
Description: Pelvic Floor Distress Inventory Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: International Consultation on Incontinence Questionnaire - Short Form
Description: International Consultation on Incontinence Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: International Consultation on Incontinence Questionnaire - Short Form
Description: International Consultation on Incontinence Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: International Consultation on Incontinence Questionnaire - Short Form
Description: International Consultation on Incontinence Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Pelvic Floor Impact Questionnaire
Description: Pelvic Floor Impact Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Pelvic Floor Impact Questionnaire
Description: Pelvic Floor Impact Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Pelvic Floor Impact Questionnaire
Description: Pelvic Floor Impact Questionnaire will be used to collect feedback on changes in the participants' life quality (to evaluate procedure efficiency).
Study NCT05000957 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior and/or posterior colporrhaphy
Description: Surgical procedure to repair pelvic organ prolapse followed by biopsy for histological, immunohistochemical studies, and optical coherence tomography (elastography).
Study NCT05000957 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior and/or posterior colporrhaphy
Description: Surgical procedure to repair pelvic organ prolapse followed by biopsy for histological, immunohistochemical studies, and optical coherence tomography (elastography).
Study NCT05000957 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Pelvic surgical procedure
Description: Any pelvic surgical procedure which do not affect condition of vagina, vulva and paraurethral region followed by biopsy for histological, immunohistochemical studies, and optical coherence tomography (elastography).
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical examination
Description: Pelvic examination (to include the participant in the study and observe throughout the study)
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Physical examination
Description: Pelvic examination (to include the participant in the study and observe throughout the study)
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Physical examination
Description: Pelvic examination (to include the participant in the study and observe throughout the study)
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Сonsultation
Description: Сonsultation of a therapist about the absence of contraindications for surgical treatment (to include the participant in the study)
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Сonsultation
Description: Сonsultation of a therapist about the absence of contraindications for surgical treatment (to include the participant in the study)
Study NCT05000957 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Сonsultation
Description: Сonsultation of a therapist about the absence of contraindications for surgical treatment (to include the participant in the study)
Study NCT05000957 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Buccal smear
Description: Buccal smear to performing genetic testing.~The following markers will be analyzed:~ESR1 rs2234693, ESR1 rs2228480, COL3A1 rs1800255, COL14A1 rs4870723, MMP9 rs3918253, MMP10 rs17435959, LOXL1 rs2304719, WNT4 rs3820282, MMP2 rs243865, TIMP2 rs2277698, CD31 / PECAM1 rs1131012, Ki67 rs11016076.
Study NCT06481709 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: RLF-OD032
Description: 100 mg/mL oral suspension
Study NCT06481709 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Kuvan
Description: 100 mg powder for oral solution
Study NCT06504615 — intervention group
Intervention type: DRUG
Intervention: nivolumab + chemotherapy
Description: As prescribed by the treating clinician, as per product label
Study NCT04986176 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HC-1119
Description: oral
Study NCT04986176 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral
Study NCT06221566 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Muscle Energy Technique
Description: Muscle energy technique (MET) for upper trapezius and levetor scapulae muscle of neck with 7 to 10 second hold, 3 to 5 repetitions.~Transcutaneous electrical nerve stimulation (TENS) with Cold pack.~Home exercise program (HEP) will receive by both the groups which will be not supervised by the principal investigator or any other investigator.
Study NCT06221566 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stretching Exercises
Description: Stretching exercises program for upper trapezius and levetor scapulae muscle of neck with 10 second hold, 15 repetitions.~Transcutaneous electrical nerve stimulation (TENS) with Cold pack.~Home exercise program (HEP) will receive by both the groups which will be not supervised by the principal investigator or any other investigator.
Study NCT05536362 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TCI Propofol Injection
Description: To decrease postoperative pain after cancer colon surgery
Study NCT05840432 — intervention group
Intervention type: DEVICE
Intervention: Postoperative hypotension prediction index
Description: Performance of the hypotension prediction index (HPI) in predicting hypotension episodes in the first 12 h of cardiac surgery postoperative
Study NCT06298916 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: 64Cu-LNTH-1363S
Description: 64Cu-LNTH-1363S, is a highly selective, high affinity FAP inhibitor (FAPi) that is radiolabeled with Copper-64 (64Cu) for PET/CT Imaging,
Study NCT05661734 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VX-548
Description: Tablets for oral administration.
Study NCT06102057 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: standard Radiotherapy
Description: standard FDG-PET-based radiotherapy
Study NCT06102057 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Chemotherapy
Description: concurrent standard of care chemotherapy
Study NCT06102057 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chemotherapy
Description: concurrent standard of care chemotherapy
Study NCT06102057 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Immunotherapy
Description: standard of care consolidation therapy with durvalumab (fixed dose of 1500 mg q4w) for up to 12 months or until progression of disease, unacceptable toxicity, patient´s wish, or investigator´s decision, whichever comes first.
Study NCT06102057 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Immunotherapy
Description: standard of care consolidation therapy with durvalumab (fixed dose of 1500 mg q4w) for up to 12 months or until progression of disease, unacceptable toxicity, patient´s wish, or investigator´s decision, whichever comes first.
Study NCT06102057 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Experimental Radiotherapy
Description: FDG-PET-based small volume accelerated radiotherapy
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Volrustomig
Description: MEDI5752: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pemetrexed
Description: Alimta: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pemetrexed
Description: Alimta: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carboplatin
Description: Paraplatin: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Paraplatin: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Cisplatin
Description: Platinol: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Nivolumab
Description: Opdivo: Administered as IV infusion
Study NCT06097728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ipilimumab
Description: Yervoy: Administered as IV infusion
Study NCT05534009 — intervention group
Intervention type: OTHER
Intervention: Follow up of the first known immunization event
Description: The baseline for enrolment into the study is defined by the occurrence of the first known immunization event, either natural infection or vaccination. The follow-up is planned to last 24 months with respect to this baseline. In subjects with natural infection, the viral variant must be determined for each prospective case by analysis of a nasopharyngeal swab obtained as soon as possible at diagnosis. For historical cases where the variant was not determined and a contemporary nasopharyngeal swab has not been stored, the viral variant may be inferred when a specific variant was dominating the geographic area according to official records available at local health agencies. However, the variant assignment will be labelled as putative, rather than proved.~HCWs can be enrolled in the category of:~(i) vaccination not followed by any later infection, (ii) infection followed by vaccination and (iii) vaccination followed by infection.
Study NCT06576726 — intervention group
Intervention type: OTHER
Intervention: This study involves no intervention.
Description: This study involves no intervention.
Study NCT04526795 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cytarabine
Description: Given IV