AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05612659 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcranial Electrical stimulation
Description: Noninvasive electrical stimulation of lateral frontal cortex.
Study NCT05612659 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transcutaneous direct current stimulation
Description: Noninvasive electrical stimulation of the T10 spinal column.
Study NCT02774694 — intervention group
Intervention type: DEVICE
Intervention: nociceptive flexion reflex (NFR) threshold (Paintracker, Dolosys GmbH, Berlin, Germany)
Description: measurement of the NFR threshold using the Paintracker device
Study NCT05522699 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cough suppressive therapy
Description: The cough suppressive therapy based on the treatment regime Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough (PSALTI) developed by S. Chamberlain et al (Thorax. 2017 Feb;72(2):129-136).
Study NCT05522699 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General healthy lifestyle instructions
Description: The general healthy lifestyle instructions are based on the recommendations from the The Public Health Agency of Sweden.
Study NCT05257733 — intervention group
Intervention type: OTHER
Intervention: None, pure observationnal study
Description: pure observationnal study
Study NCT06316622 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ultrasound
Description: measured by ultrasound
Study NCT03785769 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: HVGIC restoration with pre-etching
Description: Pre-etching of the surface with polyacrylic acid for 10 s, followed by washing and drying the cavity with cotton balls; and fill with HVGIC, inserted into the cavity with the aid of an insertion spatula and adapted to the cavity by the digital pressure technique.
Study NCT03785769 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: HVGIC restoration with non pre-etching
Description: Restoration with HVGIC, inserted into the cavity with the aid of an insertion spatula and adapted to the cavity by the digital pressure technique.
Study NCT05676983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spiky balance disc
Description: Balance discs consist of smooth and rough surface. Balance training is given to children with cerebral palsy on these two surfaces. Thanks to its balance disc structure, it plays an active role in the development of balance.
Study NCT05676983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pediatric neurodevelopmental therapy
Description: Bobath therapy
Study NCT05676983 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: smooth balance disc
Description: Balance discs consist of smooth and rough surface. Balance training is given to children with cerebral palsy on these two surfaces. Thanks to its balance disc structure, it plays an active role in the development of balance.
Study NCT04323462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Insulin Glargine
Description: Three times bolus insulin with regular or Shorter acting insulin
Study NCT04323462 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Diabetic DM
Description: Previously receiving OADs and/or basal insulin
Study NCT05367765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Flumatinib
Description: Flumatinib 600mg orally daily
Study NCT05367765 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Imatinib
Description: Imatinib 400mg orally daily (Reference drug instructions)
Study NCT05212441 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Light emitting diode therapy (LED therapy)
Description: The patient's forearm is positioned on table with palm facuing upward during the therapy. For LEDT, the center of the light spot located at approximately 50% of landmark line from the medial epicondyle to the styloid process of the ulna, which is the center belly of ﬂexor digitorum superﬁcialis. The subject's forearm maintained in the rest state without moving during the therapy. LED is performed before exercise.
Study NCT05212441 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient/family education program (Home program)
Description: Patients and their families will instructed to learn the anti contracture positioning/splinting, scar massage and exercises program, application of the custom garments and inserts, and functional training to perform them on their own at home. Written and illustrative instructions and reciprocal demonstration sessions will be provided to the children and their families to ensure successful acquisition and delivery of rehabilitation skills at home program. The therapist will be reported about compliance with the home program every couple of days
Study NCT05212441 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Patient/family education program (Home program)
Description: Patients and their families will instructed to learn the anti contracture positioning/splinting, scar massage and exercises program, application of the custom garments and inserts, and functional training to perform them on their own at home. Written and illustrative instructions and reciprocal demonstration sessions will be provided to the children and their families to ensure successful acquisition and delivery of rehabilitation skills at home program. The therapist will be reported about compliance with the home program every couple of days
Study NCT05212441 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Positioning & Splinting
Description: The wrist joint is splinted at 30 hyperextension, the MCP joint in 90 of flexion, the IP joints in extension, and the thumb in abduction. The webs of fingers kept in abduction. The hands are elevated above the level of the heart to minimize post-burn edema.~Splinting: Splints are tailored to help to maintain the functional or anti-contracture position of the injured body parts.The intervals for monitoring vary from once every hour to once every 4-6 hours, depending on types of splints and skin conditions. It is described as 10 hours on and two hours off. When the splint is taken off, active and/or passive ROM should be carried out.
Study NCT05212441 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Positioning & Splinting
Description: The wrist joint is splinted at 30 hyperextension, the MCP joint in 90 of flexion, the IP joints in extension, and the thumb in abduction. The webs of fingers kept in abduction. The hands are elevated above the level of the heart to minimize post-burn edema.~Splinting: Splints are tailored to help to maintain the functional or anti-contracture position of the injured body parts.The intervals for monitoring vary from once every hour to once every 4-6 hours, depending on types of splints and skin conditions. It is described as 10 hours on and two hours off. When the splint is taken off, active and/or passive ROM should be carried out.
Study NCT05212441 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Therapeutic Exercises
Description: 1. Passive ROM (PROM).~2. Active ROM (AROM) \& Active-assistive ROM (AAROM): The exercise will focus on extending the wrist to 45 degrees, flexing the MCP joints to 90 degrees and keeping the IP joints in full extension, while maintaining a thumb web space. The exercises will performed in the following sequences; (1) MCP joints flexion and extension with the wrist in neutral or slight extension and the IP joints in neutral position. (2) IP joints flexion to only 30-40 degrees with the wrist stabilized in the neutral or slight extension, while the MCP joints held in full extension, (3) thumb and fingers abduction and adduction, and (4) thumb opposition (tip of the thumb to tip of the small finger). Each exercise was performed for 8-10 repetition, daily, for 6 days/week.~3. Stretching exercises: A low-load (low-intensity), long-duration stretch~4. Strengthening exercises: done in static mode initially and progress to dynamic strengthening using elastic bands.
Study NCT05212441 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Therapeutic Exercises
Description: 1. Passive ROM (PROM).~2. Active ROM (AROM) \& Active-assistive ROM (AAROM): The exercise will focus on extending the wrist to 45 degrees, flexing the MCP joints to 90 degrees and keeping the IP joints in full extension, while maintaining a thumb web space. The exercises will performed in the following sequences; (1) MCP joints flexion and extension with the wrist in neutral or slight extension and the IP joints in neutral position. (2) IP joints flexion to only 30-40 degrees with the wrist stabilized in the neutral or slight extension, while the MCP joints held in full extension, (3) thumb and fingers abduction and adduction, and (4) thumb opposition (tip of the thumb to tip of the small finger). Each exercise was performed for 8-10 repetition, daily, for 6 days/week.~3. Stretching exercises: A low-load (low-intensity), long-duration stretch~4. Strengthening exercises: done in static mode initially and progress to dynamic strengthening using elastic bands.
Study NCT06296498 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Leukocyte Platelet-rich fibrin
Description: Leukocyte-PRF (L-PRF) contains neutrophils and macrophages that facilitate bacteria and necrotic tissue elimination via phagocytosis
Study NCT06296498 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard of care OFD
Description: Open flap debridement (OFD) is one periodontal surgical procedure that is used to improve periodontal health by providing access to the tooth roots and alveolar bone.
Study NCT05199870 — intervention group
Intervention type: DEVICE
Intervention: Echo FX Stem with RingLoc Bipolar Acetabular Cup and Femoral Head
Description: Patients that have been implanted with a Echo FX stem with RingLoc Bipolar acetabular cup and femoral head.
Study NCT05840913 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
Description: Local anesthetic injection for intra- operative pain control
Study NCT04722276 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: positive end expiratory pressure
Description: 7cmH2O of positive end expiratory pressure with fraction of inspired oxygen 80% applied during induction of anesthesia
Study NCT04722276 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: fraction of inspired oxygen 80%
Description: fraction of inspired oxygen 80% applied during induction of anesthesia
Study NCT05121727 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: Erector Spinae Plane Block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, when the patient is placed in the lateral decubitus position. 20 ml of 0.25% bupivacaine will be used in applications.
Study NCT05121727 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Deep and Superficial Serratus Anterior Plane Block
Description: Combined Deep and Superficial Serratus Anterior Plane Block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, when the patient is placed in the lateral decubitus position. 20 ml of 0.25% bupivacaine will be used in applications.
Study NCT04968106 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Doxorubicin will administered by intravenous infusion on day 1 every 3 weeks (75 mg/m²) up to 3 cycles
Study NCT04968106 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Doxorubicin
Description: Doxorubicin will administered by intravenous infusion on day 1 every 3 weeks (75 mg/m²) up to 3 cycles
Study NCT04968106 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ifosfamide
Description: Ifosfamide will be administered by intravenous infusion over 3 days every 3 weeks (9 g/m²) up to 3 cycles
Study NCT04968106 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Ifosfamide
Description: Ifosfamide will be administered by intravenous infusion over 3 days every 3 weeks (9 g/m²) up to 3 cycles
Study NCT04968106 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INCMGA00012
Description: Retifanlimab will be administered by intravenous infusion on day 1every 3 weeks (375 mg) up to 3 cycles
Study NCT05872464 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Artificial saliva containing cumin and ginger extract
Description: Artificial saliva containing cumin and ginger extract in spray bottle
Study NCT05872464 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo containing composition close to the test group without cumin and ginger extract in spray bottle
Study NCT06307041 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Dental floss+Gengigel
Description: 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses
Study NCT06307041 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Dental Floss
Description: Dental Flosses
Study NCT05587257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fractional CO2 laser
Description: Each patient will receive 6 sessions 2 weeks apart, after the laser treatment, a topical 5% minoxidil tincture will immediately applied.~All patients will advised not to use any other treatment during the study
Study NCT05587257 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Derma pen
Description: , will be treated by microneedling using dermapen ( automated Derma Pen, DR Pen Ultima A6, China) which under complete aseptic precaution with a cartridge containing 12 needles moved diagonally, vertically, and horizontally for 4-5 times in each direction with 1.5 mm depth and speed 4-5(new cartridge every session), the application has been extended 1-2 cm perilesionally. The pinpoint bleeding will be considered an endpoint. topical 5% minoxidil tincture will immediately applied. Each patient will receive 6 sessions 2 weeks apart.
Study NCT05587257 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niosome minoxidil
Description: The patient of alopecia areata will be treated by topical nanominoxidil preparation twice daily for 3 months with no other treatment.
Study NCT05587257 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Minoxidil Topical Spray
Description: The patient of alopecia areata will be treated by topical minoxidil 5% preparation twice daily for 3 months with no other treatment.
Study NCT06312423 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oligonucleotides, Phosphorothioate
Description: Group 1: 20 mg/day single dose Group 2: 20 mg/day for 3 days Group 3: 20 mg/day for 5 days
Study NCT06461793 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients
Description: this researcher performed biodegradable material injection during radical radiotherapy in combination with hormone therapy in high - risk prostate cancer patients. after subdivision radical received radiation therapy We plan to conduct a phase II clinical study to evaluate the safety of prostate cancer patients.
Study NCT05295082 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: guided trephination-based drilling protocol
Description: the implant site preparation in this group will be done by guided trephination protocol which uses the surgical guide to trephine the implant site then remove the guide and continue the drilling in a freehand manner
Study NCT06255470 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Non-surgical periodontal treatment
Description: Non-surgical periodontal treatment involves the removal of microbial dental plaque and calculus by mechanical debridement using manual and ultrasonic instruments. Motivating and educating patients about oral hygiene procedures is another important part of the treatment. The aim is to stop the progression of the disease and to prevent the occurrence of active clinical inflammation.
Study NCT04808154 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SNP-630
Description: Subjects will receive one single dose of SNP-630 at Day 1. Blood and urine samples will be obtained to determine the PK of orally administered SNP-630.
Study NCT06074614 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Hypercapnic ventilatory response
Description: Control of breathing is predominantly regulated by feedback of the central chemoreceptors. All chemoreceptors are sensitive to changes in partial pressure of carbon dioxide and via acid-base reactions to hydrogen concentration. The hypercapnic ventilatory response test shows the relationship between end-tidal PCO2 and the resulting minute ventilation.
Study NCT06074614 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Respiratory related evoked potential
Description: The RREP is a measure of cerebral cortical activity elicited by short inspiratory occlusion or breathing against inspiratory resistive loads and quantifies the initial arrival and further processing of sensory afferent respiratory information in the cortex.
Study NCT06074614 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Transcranial magnetic stimulation
Description: Transcranial magnetic stimulation of the diaphragm is an established tool for investigating the cortical excitability related to breathing. TMS will be delivered over the vertex using a magnetic stimulator and a 110mm double cone coil.
Study NCT04684550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Stabilized hypochlorous acid
Description: Application of 2 puffs and gargles every 8 hours of a solution with low concentrations of S-HCLO (3-5 ppm).
Study NCT04684550 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Application of 2 puffs and gargles every 8 hours of a solution with low concentrations of S-HCLO (3-5 ppm).
Study NCT06055881 — intervention group
Intervention type: OTHER
Intervention: Non-Interventional Study
Description: Non-interventional study
Study NCT05412719 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: THE EFFECT OF FINGER PUPPET MANIPULATION ON PAİN AND PHYSİOLOGıCAL PARAMETERS DURING URINARY CULTURE WITH URINARY CATHETERIZATION IN INFANTS
Description: the effect of finger puppet manipulation on pain and physiological parameters during urinary culture with urinary catheterization
Study NCT04509427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Instructional handouts
Description: Handouts will include written instructions for each aspect of the multifaceted exercise/posture training program
Study NCT04509427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical therapist instruction and monitoring via teleconferencing
Description: The intervention physical therapist (PT) meets with them via Zoom for 60 minutes to help them start the program in the first week. This PT will meet with them again in week 2 to complete initial instructions. The PT will meet with them week 3 and then every other week for 15-minutes to help individuals safely progress the program.
Study NCT04509427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Web-based instructional videos
Description: Instructional videos that will lead participants through every part of the intervention - like a commercial exercise video.
Study NCT04509427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Posture training
Description: Participants will learn how to hold a neutral spine posture during sitting, forward leaning in sitting, sit-to-stand-to-sit, standing, forward leaning in standing, supine-to-sit-to-supine, supine-to-prone-to-supine, and lifting. Principles learned with these functional movement patterns will then be put to practice in common tasks like sweeping, washing dishes, dusting, and gardening. This will be taught over two sessions in the first two weeks of the program. To reinforce holding neutral spine with all activities, participants will perform a 5-minute posture warm-up routine prior to exercising.
Study NCT04692779 — intervention group
Intervention type: OTHER
Intervention: Lung Ultrasound (LUS)
Description: Enrolled subjects will undergo LUS 1 hour before and 1 hour after prone positioning by a trained clinician and will be assessed using a LUS score based on LUS pattern. LUS will then be performed again 1 hour before supination (16 hours) and assessed by a LUS score. This process will be repeated on the first 3 prone sessions. Patients will be enrolled in the study for 4 weeks in order to observe patient outcomes.
Study NCT05745961 — intervention group
Intervention type: RADIATION
Intervention: TSPO PET scan (11C-PBR28)
Description: PET scan
Study NCT04509427 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Marching in place
Description: Participants will perform marching in place five times a week. Participants will be instructed to slowly progress to a goal of performing 30 minutes of marching in place per session. They will be instructed to lift their knees to a height that is between their waist and knee when marching. They will be instructed to march between a rating of 10 -14 on the 20-point Borg scale for rate of perceived exertion
Study NCT04600323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sodium Bicarbonate Tablets
Description: Participants will be given sodium bicarbonate at 0.5 mEq/kg-LBW/day for 12 months
Study NCT05338736 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: LIAISON SARS-CoV-2 TrimericS IgG (DiaSorin)
Description: Kit to test the concentration of Immunoglobulin G anti-SARS-CoV-2 in the plasma of included patients
Study NCT05338736 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: LIAISON SARS-CoV2-IgM (DiaSorin)
Description: Kit to test the concentration of Immunoglobulin M anti-SARS-CoV-2 in the plasma of included patients
Study NCT05338736 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Human IFN-g ELISpot PLUS (ALP) (AUROGENE)
Description: Kit to test the cellular immunity response by measuring the Interferon gamma released by mononuclear cells (PBMCs)