AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05759065 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele-Brief Behavioral Treatment for Insomnia
Description: Brief Behavioral Treatment for Insomnia (BBTI) comprises of up to five weekly intervention visits by phone, delivered by a variety of practitioners without formal training in sleep.
Study NCT05759065 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Tele-Cognitive-Behavioral Therapy for Insomnia
Description: Cognitive-Behavioral Therapy for Insomnia (CBTI) is a multicomponent strategy delivered by trained mental health clinicians over 6 to 12 weeks.
Study NCT05114564 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens A (comfilcon A lens)
Description: 1 month
Study NCT05114564 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lens B (lehfilcon A lens)
Description: 1 month
Study NCT04611139 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SP-2577
Description: Daily oral doses
Study NCT04611139 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: 200mg Q3W by IV infusion
Study NCT05740813 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-CLS-7262 Dose 1
Description: ABBV-CLS-7262 is administered orally once per day for 24 weeks.
Study NCT05740813 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ABBV-CLS-7262 Dose 2
Description: ABBV-CLS-7262 is administered orally once per day for 24 weeks.
Study NCT05740813 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Matching Placebo
Description: Matching placebo is administered orally once per day for 24 weeks.
Study NCT05338385 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mental Skills Coaching
Description: Participants will partake in a 1-hour pre-op initial intake, followed by five 30-min follow-up sessions at 2 weeks, 6 weeks, 3 months, 6 months and 9-months post-op. All sessions will be one-on-one with the same master's-level mental skills coach. At each session, the provider will allow time for participants to share their current injury experience to date (i.e. how they are doing, challenges they have encountered). Following this, participants will be introduced to a series of mental skills tools, including but not limited to mindset awareness, motivation, cognitive restructuring, goal setting, and objective performance assessment. Participants will be provided with handouts outlining the strategies addressed to help maintain consistency of mental skills engagement between sessions.
Study NCT04742881 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Low pressure + microsurgical instruments
Description: Low pressure pneumoperitoneum ((≤ 8 mmHg) and use of microsurgical instruments (3mm and 5mm instruments)
Study NCT04742881 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Low pressure + standard instruments
Description: Low pressure pneumoperitoneum ((≤ 8 mmHg) and use of standard instruments (5mm and 10mm instruments)
Study NCT06296277 — intervention group
Intervention type: OTHER
Intervention: Intraoperative mechanical ventilation for surgery
Description: Any IMV during general anesthesia for surgery
Study NCT05485714 — intervention group
Intervention type: OTHER
Intervention: Reviewing records retrospectively of patients undergoing screening endoscopy
Description: Reviewing records retrospectively of patients undergoing screening endoscopy to assess Baveno VI, expanded Baveno VI, Platelet count/spleen diameter and other non-invasive predictors of esophageal varices or varices needing treatment
Study NCT05174156 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination therapy
Description: SHR-1210 (camrelizumab) + albumin-bound paclitaxel + Carboplatin
Study NCT05567042 — intervention group
Intervention type: OTHER
Intervention: No intervention
Description: No intervention
Study NCT05822492 — intervention group
Intervention type: PROCEDURE
Intervention: Group QLB3
Description: Patients who applied the QLB3 block before PCNL surgery were included in this group~Multimodal analgesia protocol is applied to all patients undergoing PCNL surgery in our clinic. According to this protocol, patients are administered iv tenoxicam 20mg after induction of general anesthesia and iv paracetamol 1 gr intraoperatively. Postoperative analgesia: iv paracetamol 1gr every 8 hours and iv PCA of 0,2mg/ml morphine (the bolus dose is 20 mcg/kg, the lock-in time of 6-10 minutes, and the 4-hour limit is adjusted to be 80% of the calculated total dose). In cases where rescue analgesia is required (VAS score ≥4), 100 mg tramadol is administered to patients. The prophylaxis for postoperative nausea and vomiting (PONV) involved the routine administration of 8 mg IV dexamethasone to patients before induction and 0.15 mg/kg IV ondansetron 20 minutes before the end of the procedure.
Study NCT05822492 — intervention group
Intervention type: PROCEDURE
Intervention: Group ESPB
Description: Patients who applied ESP block before PCNL surgery were included in this group~Multimodal analgesia protocol is applied to all patients undergoing PCNL surgery in our clinic. According to this protocol, patients are administered iv tenoxicam 20mg after induction of general anesthesia and iv paracetamol 1 gr intraoperatively. Postoperative analgesia: iv paracetamol 1gr every 8 hours and iv PCA of 0,2mg/ml morphine (the bolus dose is 20 mcg/kg, the lock-in time of 6-10 minutes, and the 4-hour limit is adjusted to be 80% of the calculated total dose). In cases where rescue analgesia is required (VAS score ≥4), 100 mg tramadol is administered to patients. The prophylaxis for postoperative nausea and vomiting (PONV) involved the routine administration of 8 mg IV dexamethasone to patients before induction and 0.15 mg/kg IV ondansetron 20 minutes before the end of the procedure.
Study NCT05822492 — intervention group
Intervention type: OTHER
Intervention: Group Control
Description: Patients who did not use block before PCNL surgery were included in this group.~Multimodal analgesia protocol is applied to all patients undergoing PCNL surgery in our clinic. According to this protocol, patients are administered iv tenoxicam 20mg after induction of general anesthesia and iv paracetamol 1 gr intraoperatively. Postoperative analgesia: iv paracetamol 1gr every 8 hours and iv PCA of 0,2mg/ml morphine (the bolus dose is 20 mcg/kg, the lock-in time of 6-10 minutes, and the 4-hour limit is adjusted to be 80% of the calculated total dose). In cases where rescue analgesia is required (VAS score ≥4), 100 mg tramadol is administered to patients. The prophylaxis for postoperative nausea and vomiting (PONV) involved the routine administration of 8 mg IV dexamethasone to patients before induction and 0.15 mg/kg IV ondansetron 20 minutes before the end of the procedure.
Study NCT06520150 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Regional anaesthetic combined fascial plane block
Description: Prior to the procedure, the anaesthetists will receive an envelope from a person not related to the project (a hospital administrative staff member). This envelope will contain a randomly indicated method of anaesthesia based on simple randomisation. This will determine the type of regional block used during the procedure. It is important to note that the patient will not know which study group they have been classified in. Furthermore, the operator performing the procedure will not be informed of the type of anaesthesia performed. This is to ensure double-blinding. In order to ensure the highest standards of objectivity, the operator performing the procedure will not be informed about the type of block performed. This will allow us to assess the extent and quality of anaesthesia after the procedure, We will use a proprietary scale of subjective operator comfort scale.
Study NCT06520150 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ropivacaine 0.125% Injectable Solution +Lignocaine 0,25% Injectable Solution
Description: administration under ultrasound guidance of a mixture of 2 local anaesthetics in a fixed total volume
Study NCT05006118 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Radio-labeled rodatristat ethyl 600 mg
Description: Single dose of rodatristat ethyl 600 mg as an oral suspension containing a mixture of \[12C\]-rodatristat ethyl and \[14C\]-rodatristat ethyl to contain approximately 600 microcuries (uCi) of radioactivity
Study NCT04972669 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electrical Acupuncture Stimulation
Description: Participants received acupuncture at bilateral Baliao. After skin disinfection, sterile adhesive pads were placed on bilateral Baliao, and acupuncture needles were inserted through the adhesive pads. Following needle insertion, small, equal manipulations of twirling, lifting, and thrusting were performed on all needles to reach de qi. Electrodes from the electroacupuncture apparatus were attached transversely to the needle handles. The electroacupuncture stimulation lasted for 30 minutes with a continuous wave of 2-15 Hz. Participants received 3 treatment sessions per week (ideally every other day) for 6 consecutive weeks, 18 sessions in total.
Study NCT04972669 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham Acupuncture
Description: Participants received sham acupuncture at locations one inch besides bilateral Baliao without needle insertion. Electrodes from the electroacupuncture apparatus were attached transversely to the needle handles. The electroacupuncture stimulation lasted for 30 minutes with a continuous wave of 2-15 Hz. Participants received 3 treatment sessions per week (ideally every other day) for 6 consecutive weeks, 18 sessions in total.
Study NCT05342805 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Narrow gastric tube
Description: At the lesser curvature, the resection began at the point that was 5-cm from the pyloric, toward to the greater curvature, then the stomach was divided along 3 cm from the greater curvature using linear stapler
Study NCT05342805 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Narrow gastric tube
Description: At the lesser curvature, the resection began at the point that was 5-cm from the pyloric, toward to the greater curvature, then the stomach was divided along 3 cm from the greater curvature using linear stapler
Study NCT05276089 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video message
Description: The five-minute video will be sent to the patient's mobile phone, outlining reasons to reduce opioid use and highlighting the support available. It invites patients to consider 3 responses:~1. I would like to reduce my opioid medication with support.~2. I understand this video but I want to continue my current dose.~3. I would like to speak to someone to understand more. Option 1) will enable the GP practice to initiate existing opioid reduction support, Option 2) will continue care and support as usual, and Option 3) will enable the team to offer more information.
Study NCT05941247 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hemay005 60 mg
Description: The eligible healthy adult participants will enter Single-dose Administration Period, receiving a single administration of Hemay005 tablets orally at a dose of 60 mg on Day 1 morning under fasted condition.~On Day 3, those participants will receive Hemay005 tablets at dose of 60 mg for 7 consecutive days, which will be administrated twice daily (BID) during Day 3 to Day 8 and only in the morning on Day 9.
Study NCT06068764 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etomidate
Description: The type of general anesthesia induction agent for CABG surgery
Study NCT06068764 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propofol
Description: The type of general anesthesia induction agent for CABG surgery
Study NCT03867162 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Live Attenuated Tularemia Vaccine
Description: Subjects will be vaccinated with a bifurcated needle; approximately 0.06 mL of the reconstituted vaccine will be placed on the volar surface of the forearm and applied by multiple puncture.
Study NCT05312346 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: seum zinic,vit B12, parathyriod function
Description: seum zinic,vit B12, parathyriod function
Study NCT04571190 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Prenatal MBSR
Description: Prenatal MBSR is an adaptation to the original MBSR program. The essential program elements characterizing MBSR is maintained and integrated with the particular context and specific needs of this group of pregnant women. Adaptations to the MBSR program draw upon both empirical data as well as existing research and theory.
Study NCT05837377 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control- standard medication education
Description: Common Procedure:~- Student Information and Consent Form will be obtained from the students.~For the control group~* Theoretical training in drug administration skills is provided.~* Skill training: Skill training on intramuscular and subcutaneous injection and intravenous medication administration using task trainers in the simulation laboratory.~* After the skill evaluation phase, a safe drug administration scenario will be applied.
Study NCT05837377 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experiment- cognitive load theory based on medication education
Description: For the experiment group~* Theoretical training will be provided based on the results of both the knowledge test and the self-efficacy test, and will be designed according to the principles of cognitive load theory.~* Skills training: includes the necessary skill applications for students with task trainers and a virtual simulation designed according to the cognitive load theory for these skills.~* After the skill evaluation phase, a safe drug administration scenario will be applied.
Study NCT05779787 — intervention group
Intervention type: PROCEDURE
Intervention: TAVR Aligned
Description: Investigate the feasibility of coronary re-engagement after commissural alignment technique in terms of success rate (%) and procedure complexity taking into account radiations, time and contrast used.
Study NCT05779787 — intervention group
Intervention type: PROCEDURE
Intervention: TAVR Random
Description: TAVR Random Feasibility comparison of coronary re-engagement between the randomly implanted Navitor valve (unaligned) and the others implanted with the commissural alignment technique in terms of success rate (%) and complexity of the procedure, taking into account radiation, time and contrast used
Study NCT05982197 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Curcumin Gel
Description: Curcuma longa oral gel for prevention radiation induced oral mucositis
Study NCT05982197 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard Preparation
Description: Standard preparation for prevention radiation induced oral mucositis
Study NCT05156996 — intervention group
Intervention type: DEVICE
Intervention: Supersaturated O2 Therapy of the Therox Downstream System®
Description: SuperSaturated Oxygen Therapy (SSO2 Therapy) to targeted ischemic regions perfused by the patient's left anterior descending coronary artery immediately following revascularization by means of percutaneous coronary intervention (PCI) with stenting that has been completed within 6 hours after the onset of anterior myocardial infarction (AMI) symptoms caused by a left anterior descending artery infarct lesion.
Study NCT05156996 — intervention group
Intervention type: PROCEDURE
Intervention: PCI alone
Description: Percutaneous Coronary Intervention for treatment of acute MI
Study NCT04990609 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA)
Description: Endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) consists of the application of an alternating current with a frequency of 350-500 kilohertz (kHz) to the target tissue via a special electrode located at the tip of an echoendoscope. The alternating current causes the vibratory movement of ionic particles in the abutting and adjoining tissue and results in the generation of heat. However, RFA induces not only local disruption of the tumor by heat, but it also produces localized coagulation necrosis of the tumor; which induces the release of large amounts of cellular debris. This cellular debris represents a source of tumor antigens that can trigger a host adaptive immune response against the tumor.
Study NCT04990609 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Neoadjuvant Chemotherapy (NAC)
Description: The NAC regimen will be determined clinically by the participant's physician \[possible regimens are either mFOLFIRINOX or Gemcitabine Nab-Paclitaxel +/- Cisplatin (GemAbraxane)\].
Study NCT04400149 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: amniocentesis
Description: amniocentesis will be performed to the pregnant women at 16-20 weeks who had a high-risk antenatal test. Furthermore, these women also give a blood sample (at 16-20 weeks) to compare the amniotic fluid and serum progesterone levels in association with pregnancy outcomes. We perform amniocentesis to evaluate genetic disorders in pregnant women who had his risk in the antenal test.
Study NCT05234268 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Manual Cervical Traction
Description: Time: 20 minutes Duration: thrice a week for 4 weeks.~Position:~The patient is in supine lying. The head and neck of patient are held in the hands of the practitioner, and then a gentle traction of a pulling force is applied. Intermittent periods of traction can be applied, holding each position for about 10 seconds. Traction is usually applied at about 20-30 degrees of neck flexion.
Study NCT05234268 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Passive Accessory Intervertebral Movements
Description: Time: 20 minutes Duration: thrice a week for 4 weeks~Position:~Patient lying in prone. Therapist stands to side of patient placing their pisiform/ulnar surface of hand over the selected spinous process (SP) with their wrist in full extension.~Other hand placed on top of hand to reinforce. Therapist's shoulders should be directly above the SP with elbows slightly bent. Therapist uses their body weight to apply a PA force to the selected SP by leaning their body over their arms and performing rocking movements to provide oscillatory movements of the vertebra.
Study NCT05234268 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Active Strength Training
Description: Time: 20 minutes Duration: thrice a week for 4 weeks. The progression of exercises will be done using different colors of Thera-band indicating varied resistance. (A) Resistive lateral flexion of uninvolved side.~Position:~The patient is in sitting position. By the help of thera-band patient will actively flex the neck against resistance on the uninvolved side.
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Family Letter (Standard of Care)
Description: The family letter is given to probands in the standard of care arm and provides information on the familial mutation and serves to encourage first degree relatives to complete genetic testing.
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Educational Video
Description: The educational video is provided by the clinical genetic testing laboratory and explains the importance and implications of genetic testing. This educational video is shared with first degree relatives in the intervention arm
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Educational Video
Description: The educational video is provided by the clinical genetic testing laboratory and explains the importance and implications of genetic testing. This educational video is shared with first degree relatives in the intervention arm
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mailed Saliva Kit for Genetic Testing
Description: The FDR's email will be sent to the genetic testing lab, Invitae, which will allow them to log on to the online portal, create a unique account, and order a genetic testing saliva kit free of charge. The FDR will receive the kit and instructions in the mail. The FDR will collect the saliva sample and send the sample back to the genetic testing laboratory.
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Mailed Saliva Kit for Genetic Testing
Description: The FDR's email will be sent to the genetic testing lab, Invitae, which will allow them to log on to the online portal, create a unique account, and order a genetic testing saliva kit free of charge. The FDR will receive the kit and instructions in the mail. The FDR will collect the saliva sample and send the sample back to the genetic testing laboratory.
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Telephone Counseling
Description: The FDR's will be contacted and receive post genetic testing phone counseling
Study NCT04613440 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Telephone Counseling
Description: The FDR's will be contacted and receive post genetic testing phone counseling
Study NCT06071546 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MAIA
Description: MAIA is a visual field testing device combining visual field tests, fixation loss correction by a real-time retinal tracker and confocal TrueColor fundus imaging (P/N AHMACME001)
Study NCT06223308 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HB0028
Description: Patients will be assigned to dose regimens in the order of enrollment, and they will receive their assigned fixed dose of HB0028 via intravenous infusion. HB0028 IV every 3 weeks (q3w).
Study NCT05552742 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conservative rehabilitation
Description: The conservative rehabilitation program includes a patient-specific conservative exercise program comprising exercises that strengthen the paralyzed side, increase joint range of motion and strengthen muscles, stretch spastic muscles, and ensure balance rehabilitation that enhances balance performance and coordination. The patients in both groups received conservative rehabilitation program for 8 weeks, 4 days a week for 1 h.