AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05889598 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ballistic Resistance Lower Body Strength Training
Description: The exercise programme involves two supervised sessions per week at University. Each session will involve 30-40 minutes of exercise, comprising warm-up , two main exercises: a hack squat and calf raise using a hack squat machine, and core exercises. After a warm-up period involving 5 minutes cycling and one set of 5 conventional repetitions at 40%1RM, the ballistic training group will complete eccentric phase hack squat exercise in approximately 3 seconds and the concentric phase as fast as possible with throwing type contractions. If participants can, participants will be allowed to take off in the concentric phase. To maintain high velocity in this group, lower loads will be used compared to the conventional group. The load will be decided according to regular maximal muscular strength test (1RM) to use of the correct weight for training (in proportion to the strength). Participants will start off using light weights and these will increase as participants become stronger.
Study NCT05889598 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Resistance Lower Body Strength Training
Description: The exercise programme involves two supervised sessions per week at Loughborough University. Each session will involve 30-40 minutes of exercise, comprising warm-up , two main exercises: a hack squat and calf raise using a hack squat machine, and core exercises. After a warm-up period involving 5 minutes cycling and one set of 5 conventional repetitions at 40% of 1RM, the conventional training group will complete eccentric and concentric phases of hack squatting exercises for approximately 3 seconds each, with appropriate breathing techniques. The load will be decided according to regular maximal muscular strength test (1RM) to use of the correct weight for training (in proportion to the strength). Participants will start off using light weights and these will increase as participants become stronger.
Study NCT05707117 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tendon neuroplastic training (TNT)
Description: Subjects will attend physical therapy for three non-consecutive days per week for a total 4 consecutive weeks. Exercise would involve isolated flexion, extension with a dumbbell. This exercise would be paced with external audio/visual cue on smart phone using proMetronome app. Patients will listen to the sound and track the movement of metronome with the eyes. Pace of metronome will be set at 20 beats per minute such that each beat will be 3 sec apart. This will allow a 3sec concentric and 3 sec eccentric phases.4 sets of 8 repetitions would be completed with a 2-minute rest between each set. Exercise will begin with 3 pounds weight, but it would be made sure that this wouldn't cause pain during exercise (more than 5/10), gradual progression in weight to 5 pounds after 2nd weeks.
Study NCT05707117 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: group B Conventional treatment
Description: Subjects assigned to this group will undergo static stretching of Extensor carpi radialis brevis and myofascial release for 4 weeks, 3 sessions a week. Myofascial release technique will be applied for 5 minutes and 2 reptations per session
Study NCT04871672 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home Exercise program
Description: home exercise
Study NCT06158113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Baricitinib 4 milligram Oral Tablet
Description: 4 milligrams once daily
Study NCT04712552 — intervention group
Intervention type: PROCEDURE
Intervention: deep brain stimulation
Description: On the day of surgery, under general anesthesia, a Fischer ZD frame will be attached to the skull. A T1-weighted 3D MRI with gadolinium will be performed.~Investigators will plan on this MRI, anatomical targets and deep brain trajectories using the NeuroInspire surgical planning software.~The patient will be attached to the base of the robot through the frame. Registration will be performed using the Neurolocate method after the acquisition of 3D CT images using the O-arm. The Neurolocate recording is based on radiographic images.The 3D MRI will be merged with the 3D tomography images taken with the O-arm to co-register the trajectories planned on the MRI in the robot space The surgical procedure will be performed as usual by milling the bone at the entry point and inserting under robotic guidance an electrode through a guide tube to the intended target.
Study NCT01671631 — intervention group
Intervention type: OTHER
Intervention: Measurement of intracoronary pressure
Study NCT05080374 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Manipulation + exercise program
Description: high-speed, low-amplitude spinal manipulation plus a trunk exercise program
Study NCT05080374 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal manipulation + Kinesiotaping
Description: high-speed, low-amplitude spinal manipulation plus elastic bandage (Kinesiotaping) application to the trunk area
Study NCT05080374 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: spinal manipulation + respiratory exercise
Description: high-speed, low-amplitude spinal manipulation plus a breathing exercise program for the diaphragmatic muscles
Study NCT06372899 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: E-cigarettes
Description: Participants randomized to ECIGS are instructed to switch from smoking combustible cigarettes to using e-cigarettes for 6 weeks. They will be provided with an e-cigarette device and nicotine pods.
Study NCT06036316 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Language assessment
Description: The proposed speech and language therapy assessment will consist of a battery of standardized tests that speech and language therapists can use to assess the language skills in reception and expression of adult patients.~Concerning the assessment of the interactions between working memory and semantic abilities, a complete protocol has been developed.
Study NCT06036316 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: TLC - Scale for the Assessment of Thought, Language, and Communication
Description: This scale is frequently used in psychiatry and is used to measure formal thought disorders in patients suffering from psychosis. As part of this study, it will be intended for patients suffering from schizophrenia
Study NCT06036316 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MINI - Mini International Neuropsychiatric Interview
Description: This scale corresponds to a rapid assessment of the psychiatric and psychological state of patients. It helps detect any psychiatric disorders. Here, it will be offered to volunteers who are part of the control group.
Study NCT06036316 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: CAST - Cannabis Abuse Screening Test
Description: The purpose of this questionnaire is to approximate participants' cannabis consumption and to assess any disorders associated with cannabis consumption. It will be offered to all participants, patients and healthy controls
Study NCT05286866 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dental implant bed preparation
Description: Drilling an osteotomy for placement of a dental implant
Study NCT05286866 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dental implant bed preparation
Description: Drilling an osteotomy for placement of a dental implant
Study NCT05761665 — intervention group
Intervention type: OTHER
Intervention: Evaluation
Description: Kinesiophobia=Tampa scale Balance=Berg Balance Scale Falling=The Fall Activity Scale( Tinetti) Walking speed=Timed Get Up and Walk Test ,Two-Minute Walking Test Fragility=Frail Fragility Questionnaire, Clinical Fragility Scale
Study NCT06372899 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral nicotine pouches
Description: Participants randomized to ONPS are instructed to switch from smoking combustible cigarettes to using nicotine pouches for 6 weeks. They will be provided with nicotine pouches.
Study NCT06253962 — intervention group
Intervention type: OTHER
Intervention: coronary agiongraphy
Description: severity of coronary atherosclerosis
Study NCT05460156 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bridges Self-management Support
Description: Self-management support intervention tailored for people with neuromuscular diseases
Study NCT04915417 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic Ablative Body Radiotherapy (SABR)
Description: Patients will receive 27-30 Gy in 3 fractions to the planning target volume (PTV) with a simultaneous in-field boost to the metabolically active areas of the gross tumor volume (GTV) to a maximum of 45 Gy. Patients will be treated every other day.
Study NCT05434520 — intervention group
Intervention type: PROCEDURE
Intervention: Preoperative biliary drainage (ERC og PTC-aided)
Description: Placement of biliary stent (plastic, covered SEMS, uncovered SEMS) endoscopic by ERC or placement of plastic catheter by PTC
Study NCT06435533 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: low energy argonplasma coagulation
Description: see above
Study NCT05324124 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Selpercatinib
Description: Administered orally.
Study NCT05408026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Daratumumab (and hyaluronidase) will be given over 3-5 minutes subcutaneously (under the skin) in the clinic at alternating left/right abdominal sites. Patient will take dexamethasone orally (by mouth) either before coming to clinic or in clinic, before other medications.~Only for the first cycle, patient will receive on Day 1 daratumumab (which is mixed with a compound called hyaluronidase) and dexamethasone, 1 day before patient start the other 2 medications.
Study NCT05408026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pomalidomide
Description: On day 2 of cycle 1, patient will start the other medications and will therefore receive bortezomib administered subcutaneously (SC) over 3-5 minutes and dexamethasone given orally (by mouth), either before coming to clinic or in clinic, before bortezomib. Patient will also start pomalidomide on the same day, which patient will take that evening at home and every evening for 21 days.
Study NCT06515262 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Anti-BCMA-GPRC5D CAR-T cells infusion
Description: Subiects who meet the enrollment conditions will receive intravenous infusion of anti-BCMA-GPRC5D CAR-T Cells after lymphodepleting therapy.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Colgate Cavity Protection Toothpaste
Description: Participants will use Colgate Cavity Protection Toothpaste for brushing teeth twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Colgate Cavity Protection Toothpaste
Description: Participants will use Colgate Cavity Protection Toothpaste for brushing teeth twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: American Dental Association (ADA) Ref Toothbrush
Description: Participants will use soft bristled Toothbrush for brushing teeth twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: American Dental Association (ADA) Ref Toothbrush
Description: Participants will use soft bristled Toothbrush for brushing teeth twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 1 Mouth Rinse
Description: Participants will use 20 mL of Prototype 1 Mouth Rinse for 30 seconds after brushing twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 2 Mouth Rinse
Description: Participants will use 20 mL of Prototype 2 Mouth Rinse for 30 seconds after brushing twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Prototype 3 Mouth Rinse
Description: Participants will use 20 mL of Prototype 3 Mouth Rinse for 30 seconds after brushing twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Listerine Cool Mint Mouth Rinse
Description: Participants will use 20 mL of Listerine Cool Mint Mouth Rinse for 30 seconds after brushing twice daily.
Study NCT05120141 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Hydroalcohol Mouth Rinse
Description: Participants will use 20 mL of Hydroalcohol Mouth Rinse for 30 seconds after brushing twice daily.
Study NCT05009667 — intervention group
Intervention type: DEVICE
Intervention: Angiography-derived Index of Microcirculatory Resistance
Description: caIMR will be measured by pressure sensors which are produced by Suzhou Rainmed Medical Technology Co., Ltd.~caIMR is calculated based on angiography images and Hyperemic Pa estimated from resting Pa according to prespecified equation.
Study NCT05009667 — intervention group
Intervention type: DEVICE
Intervention: Pressure wire-based Index of Microcirculatory Resistance
Description: IMR will be measured by thermodilution method with pressure wire and arterial physiological detector which are produced by St. Jude Medical.~IMR = Pd ∙Tmn
Study NCT05186649 — intervention group
Intervention type: OTHER
Intervention: WARFARIN
Description: 5 mg of daily dosage
Study NCT05790317 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical Procedure with ERAS Protocol
Description: It covers the period before, during and after the surgery.
Study NCT05034588 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiac magnetic resonance scan
Description: Multiparametric cardiac magnetic resonance, including functional and structural parameter
Study NCT05208788 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biomarker test
Description: collection of 500µl to 1 ml of a spot urine sample
Study NCT05647642 — intervention group
Intervention type: DRUG
Intervention: Precedex and dormicum
Description: Premedication
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Whole-genome genotyping
Description: Using Whole-genome genotyping from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Whole-genome sequencing
Description: Using whole-genome sequencing from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease to investigate the difference among the genetic variant, gene copy number, single nucleotide variation, chromosomal recombination, and very low-level gene expression differences.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: TCM pattern
Description: We want to use TCM pattern to investigate the difference among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease.
Study NCT06281951 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl - Inhalation by facial nebulization
Description: 3 administrations based on a weight-dependent threshold (40 µg per administration for a weight \< 70kg and 50 µg per administration for a weight ≥ 70kg).
Study NCT06281951 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fentanyl - Nebulisation
Description: 3 administrations based on a weight-dependent threshold (20 µg/administration and for a weight \< 70kg and 30 µg/administration for a weight ≥ 70kg). The dose of each bolus will be distributed at equivalent volume in both nasal pits
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: DNA Exome sequencing
Description: The DNA of dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease will take to do the DNA Exome sequencing.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Physical examination indicators, blood, urine and biochemical function test
Description: To investigate the difference of Physical examination indicators, blood, urine and biochemical function test among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Demographics, personal health behavior, living environment, dietary status, family history
Description: To investigate the difference among the demographics, personal health behavior, living environment, dietary status, family history of among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease.
Study NCT05117541 — intervention group
Intervention type: OTHER
Intervention: Interview
Description: Participate in interviews
Study NCT05117541 — intervention group
Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo collection of hair samples
Study NCT05117541 — intervention group
Intervention type: OTHER
Intervention: Electronic Health Record Review
Description: Medical records are reviewed
Study NCT01376765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aluminum hydroxide adjuvant (Alhydrogel®)
Description: Aluminum hydroxide adjuvant (Alhydrogel®);given with SARS vaccine; 2 intramuscular doses, 28 days apart, Cohort 1: 12 subjects given vaccine with adjuvant at 5 micrograms per dose; Cohort 2: 12 subjects given vaccine with adjuvant at 15 micrograms per dose; Cohort 3: 12 subjects given vaccine with adjuvant at 45 micrograms per dose
Study NCT01376765 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Phosphate buffered saline Placebo
Description: Phosphate buffered saline Placebo; 2 intramuscular doses, 28 days apart. Cohort 1: 4 subjects given placebo at 5 micrograms per dose; Cohort 2: 4 subjects given placebo at 15 micrograms per dose; Cohort 3: 4 subjects given placebo at 45 micrograms per dose
Study NCT01376765 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Recombinant S protein SARS vaccine
Description: Recombinant S protein severe acute respiratory syndrome (SARS) vaccine given with adjuvant or without adjuvant; 2 intramuscular doses, 28 days apart, Cohort 1: 12 subjects given vaccine only or vaccine with adjuvant at 5 micrograms per dose; Cohort 2: 12 subjects given vaccine only or vaccine with adjuvant at 15 micrograms per dose; Cohort 3: 12 subjects given vaccine only or vaccine with adjuvant at 45 micrograms per dose
Study NCT04597840 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Incisional hernia repair with reinforcement of biosynthetic mesh
Description: The biosynthetic mesh (Phasix or Bio-A meshes) will be placed as a sublay in the retromuscular position to reinforce midline fascial closure. All the surgical procedure (including placement and fixation of the mesh) will be performed according to a standardized protocol.
Study NCT04597840 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Incisional hernia repair with simple suture or synthetic mesh reinforcement.
Description: Based on the discretion of the surgeon, the incisional hernia repair will be done by simple suture or by synthetic mesh reinforcement. All the surgical procedure (including placement and fixation of the mesh if applicable) will be performed according to a standardized protocol.
Study NCT05384509 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: solid organ malignancies treatment
Description: Major inclusion criteria for this cohort of the study included: (1) age above 20 years; (2) presence of solid organ malignancies treated with immunotherapy, chemotherapy, Target therapy irrespective of the treatment phase; and (3) eligibility for vaccination.
Study NCT06295757 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Cigarettes
Description: Participants will smoke their own usual brand cigarettes. Cigarette butts will be collected.
Study NCT05231291 — intervention group
Intervention type: OTHER
Intervention: hand grip strength
Description: Observational study
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: HLA typing
Description: Using HLA typing from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease to investigate the difference among the genetic variant, gene copy number, single nucleotide variation, chromosomal recombination, and very low-level gene expression differences.
Study NCT05464849 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Evaluation of systemic skin microvascular endothelial function
Description: Laser-based method for evaluating non-invasive, operator-independent systemic microvascular function that detects microvascular flow in the skin for the evaluation of systemic vascular endothelial function.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Full-length 16S Amplicon Sequencing
Description: Using Full-length 16S Amplicon Sequencing from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease to investigate the difference among the genetic variant, gene copy number, single nucleotide variation, chromosomal recombination, and very low-level gene expression differences.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Epigenomic
Description: Using Epigenomic from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease to investigate the difference among the genetic variant, gene copy number, single nucleotide variation, chromosomal recombination, and very low-level gene expression differences.
Study NCT03938207 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Metabolomics
Description: Using Metabolomics from Taiwan Biobank among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease to investigate the difference among the genetic variant, gene copy number, single nucleotide variation, chromosomal recombination, and very low-level gene expression differences.
Study NCT05257902 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: choline alphoscerate
Description: 400mg bid/day
Study NCT05257902 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo 1T bid/day
Study NCT05095168 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CAN106
Description: CAN106 is a selective inhibitor of complement activation, which binds to the complement component C5.
Study NCT05095168 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo