AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04833023 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Haldol 2mg/ml oral solution
Description: Starting dose: 1mg~Maximum Dose within 24 hours: 6mg~Doses can be escalated every 2 hourly to the maximum doses allowed within 24 hours. If maximum dose of Haloperidol has been reached for the day (within 24 hours), rescue dose of Midazolam 2mg can be used (2mg Q2H PRN).
Study NCT04833023 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Olanzapine Actavis 5mg orodispersible tablet
Description: Starting dose: 2.5mg~Maximum Dose within 24 hours: 15mg~Doses can be escalated every 2 hourly to the maximum doses allowed within 24 hours. If maximum dose of Olanzapine has been reached for the day (within 24 hours), rescue dose of Midazolam 2mg can be used (2mg Q2H PRN).
Study NCT06530407 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Static streching exercise
Description: Static stretching exercises were applied to the M. Gastrocnemious and M. Hamstring muscle groups. The exercises were applied as a set, with three repetitions for 15 seconds on each leg, with a 20-second rest between repetitions. Static stretching was applied by slowly stretching the relevant muscle group to the point of sensitivity, without straining the pain threshold, and waiting in that position. All stretching exercises lasted an average of 6 minutes.
Study NCT06535672 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kamishibai education
Description: Patients in the intervention group will be given Kamishibai diabetes education.
Study NCT06535672 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: routine education
Description: Patients in the control group will be given routine diabetes education.
Study NCT05360875 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Endometrial scratching
Description: An intrauterine procedure that causes mild endometrial injury
Study NCT05006365 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcranial Pulse Stimulation
Description: A total of 30 participants (both TPS group and the waitlist control group) will receive six 30 minute-TPS sessions (300 pulse in each session, total: 1800 pulse) in 2 weeks' time (i.e., 3 sessions (Monday, Wednesday, Friday) per week, total: 3 hours), on a 1: 1 allocation ratio. Participants will be followed up at 3-month period after the intervention. A 2-week TPS intervention alongside with 3-month follow-up is sufficient enough to test the effects of TPS on depressive symptoms.
Study NCT05006365 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Transcranial Pulse Stimulation
Description: A total of 30 participants (both TPS group and the waitlist control group) will receive six 30 minute-TPS sessions (300 pulse in each session, total: 1800 pulse) in 2 weeks' time (i.e., 3 sessions (Monday, Wednesday, Friday) per week, total: 3 hours), on a 1: 1 allocation ratio. Participants will be followed up at 3-month period after the intervention. A 2-week TPS intervention alongside with 3-month follow-up is sufficient enough to test the effects of TPS on depressive symptoms.
Study NCT04773171 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Computer-assisted Cognitive Remediation
Description: Drill practice and bridging activities
Study NCT04773171 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional training programmes
Description: Existing conventional activities in the settings
Study NCT06254391 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Low-dose aspirin
Description: Implementation of low-dose aspirin (30 mg)
Study NCT04725565 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Genetics ADvISER Decision Aid Plus Standard Genetic Counselling
Description: The decision aid will educate patients about the types of incidental finding they can learn from genomic sequencing and will give them opportunity select what types of results they would like to receive.
Study NCT04725565 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Genetic Counseling
Description: Standard Genetic counseling to learn about and select incidental results from genomic sequencing.
Study NCT04858074 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hypoestoxide
Description: Its active pharmaceutical ingredient (API) is Hypoestoxide, discovered in 1983, which was recently shown to be active against alpha synuclein and was very effective in modifying disease progression in a transgenic mouse model of PD
Study NCT04858074 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Hypoestoxide
Description: Its active pharmaceutical ingredient (API) is Hypoestoxide, discovered in 1983, which was recently shown to be active against alpha synuclein and was very effective in modifying disease progression in a transgenic mouse model of PD
Study NCT05713890 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Home-based Action Observation Treatment with virtual-reality for upper limb rehabilitation
Description: Observation of a VR scenario depicting multiple repetitions of a specific upper limb motor task belonging to typical activities of daily living, followed by mental imagination of the action observed and then by the execution of the same task, using objects provided in a kit.~In each session, patients will watch 2 different videos and will perform the two corresponding actions. The time scheduled for observation, imagery and execution of each action will be of 5, 3, and 7 minutes, respectively, so that each session will last about 30 minutes. New actions, chosen from a dataset of 50 stimuli showing progressively increasing levels of difficulty, will be weekly administered on the basis of patient's degree of motor impairment, to involve different manual skills.~30 minutes sessions, 5 times a week for 3 consecutive weeks (15 sessions in total).
Study NCT05713890 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Home-based landscape observation with virtual-reality for upper limb rehabilitation
Description: Observation of virtually explorable landscapes followed by rest with eyes closed without focusing on any thought in particular and then execution of the same actions requested to VR-AOT-group. In each session, patients will explore 2 different landscapes and perform 2 different actions. The time scheduled for observation, rest and action execution will be of 5, 3, and 7 minutes, respectively, so that each session will last about 30 minutes.New actions, chosen from a dataset of 50 stimuli showing progressively increasing levels of difficulty, will be weekly administered on the basis of patient's degree of motor impairment, to involve different manual skills.~30 minutes sessions, 5 times a week for 3 consecutive weeks (15 sessions in total).
Study NCT04817098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Journey of Life
Description: The concept underlying the JoL intervention is that caregivers and community members can support each other and their children through reflection, dialogue, and action. JoL addresses children's and adolescents' ecologies by working with caregivers, educators, and community members to understand the importance of their support in protecting children.
Study NCT04817098 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Journey of Life
Description: The concept underlying the JoL intervention is that caregivers and community members can support each other and their children through reflection, dialogue, and action. JoL addresses children's and adolescents' ecologies by working with caregivers, educators, and community members to understand the importance of their support in protecting children.
Study NCT05243654 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metformin
Description: Metformin 1000mg XR OD + standard-of-care MDT
Study NCT05243654 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo + standard-of-care MDT
Study NCT06053879 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biofeedback electrical stimulation
Description: biofeedback stimulation for faecal incontinence post Posterior Sagittal Anorectoplasty
Study NCT06352788 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Modular Carbon Fiber Custom Dynamic Orthosis (CDO)
Description: The CDO will use a modular design that includes a full length foot plate, a posterior carbon fiber strut, and a proximal cuff that wraps around the leg just below the knee.
Study NCT06352788 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
Description: The CDO will use a mono design that includes a full length foot plate, a posterior carbon fiber strut, and a proximal cuff that wraps around the leg just below the knee.
Study NCT06345859 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Heart rate variability biofeedback
Description: This is a Phase 2 parallel intervention design with random assignment. We will randomly assign participants to one of two biofeedback conditions. Both conditions involve completing breathing exercises at home, 30 minutes per day for 10 days, while receiving continuous feedback about parasympathetic activity from the computer.
Study NCT06345859 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Heart rate variability biofeedback
Description: This is a Phase 2 parallel intervention design with random assignment. We will randomly assign participants to one of two biofeedback conditions. Both conditions involve completing breathing exercises at home, 30 minutes per day for 10 days, while receiving continuous feedback about parasympathetic activity from the computer.
Study NCT05302401 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: intrapartum uninterrupted midwife support
Description: Prenatal women will be trained about the birth process and psychological and physical support will be provided to women during childbirth. Among these supports, healthy women will be exercised during the labor action, given positions that facilitate childbirth, their hands will be held when they need them, their oral intake will not be restricted, and warm showers will be applied according to their wishes. (These applications can be increased.)
Study NCT05370950 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1209
Description: SHR-1209，single subcutaneous injection of 450mg
Study NCT05220852 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Dry needling with exercise
Description: At the initial session, dry needling will be given to their upper trapezius muscles' hyperactive trigger sites, and EX will continue for a minimum of three times per week.~1. Cranio-cervical spine flexion is the exercise.~2. Extension of the cranio-cervical spine Exercice 3 Shoulder Elevation 4-Retraining of the scapular muscles Every exercise should be done for 30 se
Study NCT05220852 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise
Description: patients in this group are going to have onley neck exercise for 2 weeks minimum 3 times a week.~1. Cranio-cervical spine flexion is the exercise.~2. Extension of the cranio-cervical spine Exercice 3 Shoulder Elevation 4-Retraining of the scapular muscles Every exercise should be done for 30 se
Study NCT05820815 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: in-bed self-exercises based on EMG-sensor feedback intervention
Description: It presents the exercise method and amount of exercise for self-exercise and performs self-exercise while receiving feedback from muscle activity during self-exercise.
Study NCT05528289 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AIRVO 2, with conventional symmetric nasal cannula
Description: The patients will be asked to breathe with HFNC at flow of 40 L/min with the standard cannula~The size of nasal cannula will be selected to occlude patient's nostril of about 2/3.~Temperature will be set according to the patient's tolerance starting from 31°C, up to 37°C, while FiO2 is adjusted to maintain SpO2 between 88 and 92%.
Study NCT05528289 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AIRVO 2, the new asymmetric nasal cannula
Description: The patients will be asked to breathe with HFNC at flow of 40 L/min with the new asymmetric nasal cannula~The size of nasal cannula will be selected to occlude patient's nostril of about 2/3.~Temperature will be set according to the patient's tolerance starting from 31°C, up to 37°C, while FiO2 is adjusted to maintain SpO2 between 88 and 92%.
Study NCT06004076 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Release of upper track of deep front fascial line
Description: I will work on upper track of deep front fascial line, I will make release to diaphragm,mediastinum,scalene muscles, scalene fascia,Fascia endothoracic, transversus thoracis,Infrahyoid muscles, fascia pretracheal and Suprahyoid muscles.
Study NCT06004076 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Corrective exercises for upper crossed syndrome
Description: strength for scapular muscles and deep neck flexor
Study NCT06004076 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Corrective exercises for upper crossed syndrome
Description: strength for scapular muscles and deep neck flexor
Study NCT04998773 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Theta Burst Transcranial Magnetic Bilateral Stimulation
Description: TMS protocol of 22 sessions of bilateral active 1800 pulses.
Study NCT04998773 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Theta Burst Transcranial Magnetic Sham Stimulation
Description: TMS protocol of 22 sessions of sham bilateral 1800 pulses.
Study NCT04998773 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Theta Burst Transcranial Magnetic Unilateral Stimulation
Description: TMS protocol of 22 sessions of left active 1800 pulses and right sham 1800 pulses.
Study NCT04343040 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: carbohydrate supplement (Preload™)
Description: carbohydrate supplement (Preload™) will be administered 4-hours prior to bariatric surgery (experimental treatment) Preload™ is a neutral-tasting carbohydrate loading drink mix specifically designed for use before elective surgery. Preload is presented in 50g pre-measured sachets which when added to water (400ml) produces a solution with low osmolality.
Study NCT04343040 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: 6 hours of preoperative fasting
Description: Standard of care. In this group, patients continue the standard of care treatment before surgery with fasting recommended 6 hours before surgery.
Study NCT05006079 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: immediate release oral 15mg dose
Study NCT05006079 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alprazolam
Description: oral 0.25mg dose
Study NCT05006079 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Lactose
Study NCT05361954 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: STI-1386
Description: Second generation oncolytic virus
Study NCT05321121 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedotomidine for Acute Pain Control in Patients with Multiple Rib Fractures
Study NCT05321121 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The control arm will receive an infusion of normal saline
Study NCT05634226 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hands-free oral-positive pressure device (oPEP)
Description: This is a pilot study using a novel, minimal risk, portable, hands-free oral-positive pressure device (oPEP) in patients with Fontan palliation that will examine whether using this device in both the acute and chronic phase will alter Fontan hemodynamics and create pulsatility in the Fontan circuit and thereby increasing cardiac output. This device is easy to use and poses no significant risk to human subjects. We will measure this through echocardiographic measures including pulsatility in different aspects of the Fontan circuit including IVC, hepatic veins, the Fontan conduit, and pulmonary arteries and aortic blood flow measurements. After demonstration of how to use the device appropriately, we will have patients use the device after their clinical echocardiogram for their clinic appointment. We will ask them to use the device at home 3-4 times a day for 10-15 mins and have them return in approximately 4 weeks to have another echocardiogram done with the same measurements.
Study NCT06634667 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: third-generation EGFR-TKI combined with anlotinib
Description: third-generation EGFR-TKI combined with anlotinib as maintenance therapy following 4 to 6 cycles of chemotherapy and immunotherapy until progressive disease.
Study NCT06635278 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness meditation
Description: The experimental group received eight 60-minute weekly sessions of mindfulness meditation over eight weeks in a private and quiet room at the hospital, according to Smith's (2005) recommendation. The study intervention was an audio based MBI sent to them by the WhatsApp application. It is a free, self-paced program developed by a study researcher based on the Smith's (2005) protocol.~The theory-based program (Smith, 2005) includes the ABC standardized versions of MBI (Smith, 2005), described as follows:~* Meditation of the body (Body sense meditation)~* Meditation of the body (Rocking meditation)~* Meditation of the body (Breathing meditation)~* Meditation of mind (Mentra meditation)~* Meditation of mind (visual Image)~* Meditation of sense (External image)~* Meditation of the senses (A sound)~* Open monitoring (Mindfulness)
Study NCT05040815 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: chemo-radiation treatment
Description: Radiotherapy (RT) with concurrent 5-fluorouracil and mitomycin-C (5FU/MMC) combination is the treatment of choice for non-metastatic locally advanced anal squam
Study NCT05622552 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: active group of tDCS
Description: Transcranial direct current stimulation(tDCS) is a neurostimulation that has aroused concern in psychiatry. As a non-invasive brain modulation that delivered a weak direct current (0.5-2 mA) via two scalp electrodes (an anode and a cathode) overlying targeted cortical areas. It can produce polarity-dependent effects, like inducing functional changes in resting membrane potential and cerebral blood flow. Specifically, a depolarization of the neurons membranes by anodal stimulation and thus invokes an increase of the spontaneous neuronal firing rate, whereas cathodal stimulation induces neuronal hyperpolarization.~In the active group, current stimulations were gradually ramped up to 2 mA (in 30 seconds) intensity for 20 minutes, once a day, for 10 days.
Study NCT05622552 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham group of tDCS
Description: Transcranial direct current stimulation(tDCS) is a neurostimulation that has aroused concern in psychiatry. As a non-invasive brain modulation that delivered a weak direct current (0.5-2 mA) via two scalp electrodes (an anode and a cathode) overlying targeted cortical areas. It can produce polarity-dependent effects, like inducing functional changes in resting membrane potential and cerebral blood flow. Specifically, a depolarization of the neurons membranes by anodal stimulation and thus invokes an increase of the spontaneous neuronal firing rate, whereas cathodal stimulation induces neuronal hyperpolarization.~For sham stimulation, the procedure was identical, except that the current was gradually ramped up to 2mA and rapidly down to zero (in 30 seconds), thus leading to the same initial sensations of tDCS.
Study NCT06319521 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: Rehabilitation therapy includes Diet management: Avoiding consumption of irritant foods and beverages, such as spicy foods, caffeine, alcohol, and acidic foods. Controlling portion sizes and meal timing, and adopting smaller, more frequent meals.~Lifestyle adjustments: Avoiding lying down or bending immediately after meals, maintaining a sitting or upright position for at least 2 hours. Adjusting sleeping positions by elevating the head of the bed to reduce nighttime acid reflux. Avoiding excessive exertion and managing stress levels.~Rehabilitation training: Strengthening the control of esophageal and gastric muscles through rehabilitation exercises to improve the function of the gastroesophageal sphincter and prevent gastric fluid reflux.
Study NCT06319521 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Rehabilitation therapy
Description: Rehabilitation therapy includes Diet management: Avoiding consumption of irritant foods and beverages, such as spicy foods, caffeine, alcohol, and acidic foods. Controlling portion sizes and meal timing, and adopting smaller, more frequent meals.~Lifestyle adjustments: Avoiding lying down or bending immediately after meals, maintaining a sitting or upright position for at least 2 hours. Adjusting sleeping positions by elevating the head of the bed to reduce nighttime acid reflux. Avoiding excessive exertion and managing stress levels.~Rehabilitation training: Strengthening the control of esophageal and gastric muscles through rehabilitation exercises to improve the function of the gastroesophageal sphincter and prevent gastric fluid reflux.
Study NCT06319521 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stellate ganglion block
Description: The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.