AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06250478 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Dynamic ultrasound of the calf muscles
Description: Dynamic changes of the calf muscles during walking will be assessed in persons after stroke and compared to healthy controls
Study NCT06250478 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Dynamic ultrasound of the calf muscles
Description: Dynamic changes of the calf muscles during walking will be assessed in persons after stroke and compared to healthy controls
Study NCT06277518 — intervention group
Intervention type: PROCEDURE
Intervention: Surgery for malignant tumors of the digestive system
Description: Related treatment or palliative surgery under general anesthesia for digestive system malignancies
Study NCT04635085 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Empowerment-based Cognitive behavioral therapy for insomnia for MCI
Description: Participants in the intervention group will participate in a 12-week empowerment-based CBT-I comprising face-to-face sessions supplemented with telephone follow-ups. In total, six face-to-face sessions (90 minutes/session) will be conducted in a small group format with 6-8 participants in a group.
Study NCT05591170 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cholecalciferol 120 000 IU
Description: single, oral administration of high dose of vitamin D
Study NCT06478576 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: multibranched stent graft system
Description: To evaluate the feasibility of multibranched stent graft system for Endovascular Treatment of Thoracoabdominal Aortic Aneurysm(TAAA)
Study NCT05546736 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iCanWork Intervention
Description: Participants will receive RTW support from the VRC and OT.
Study NCT05980143 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Metacognitive Therapy
Description: The transdiagnostic Metacognitive model suggests that psychological difficulties arise from the activation of a thinking style called the CAS (Cognitive Attentional Syndrome). Metacognitive Therapy (MCT) aims to bring the CAS under control. The therapist helps the patient to learn new ways of relating to stressful thoughts.
Study NCT05162196 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: SBRT
Description: 24Gy/3F
Study NCT05162196 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab 240mg, ivgtt, d1, q3w.
Study NCT05162196 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Niraparib
Description: 200mg qd
Study NCT05992636 — intervention group
Intervention type: PROCEDURE
Intervention: pneumoperitoneum insufflation (flow) rate
Description: Patiens who initiate with low insufflation flow (10 lt/min)~Patiens who initiate with high insufflation flow (40 lt/min)
Study NCT06400797 — intervention group
Intervention type: OTHER
Intervention: estimation of patient outcome by health care providers
Description: On day 1 after study inclusion as well as day 4-7, the responsible health-care providers (at least one nurse, one resident and one consultant with the board certification intensive care medicine) will estimate the patient's expected functional outcome at 6 and 12 months after the start of ECMO therapy. Health-care providers responsible for the patient at that time will be surveyed (multiple questionnaires to detect specific differences within one person are not planned). For the purpose of functional outcome estimation, the modified Rankin scale (mRS) is used.
Study NCT04775550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab
Description: Subcutaneous, dosage per protocol, dose days vary per cycle. Cycle =28 days
Study NCT04775550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bortezomib
Description: Subcutaneous, dosage per protocol, dose days vary per cycle. Cycle =28 days
Study NCT04775550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lenalidomide
Description: Oral, dosage per protocol, days 1-21 per cycle
Study NCT06067022 — intervention group
Intervention type: OTHER
Intervention: observation
Description: Planned measurements and scales will be applied
Study NCT05673499 — intervention group
Intervention type: DEVICE
Intervention: NIRS/EEG monitoring
Description: The study intervention will be monitoring NIRS and EEG for one hour before surgery, during surgery, and up to 8-24 hours after surgery.
Study NCT04775550 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexamethasone
Description: Oral, dosage per protocol, dose days vary per cycle. Cycle =28 days
Study NCT06304740 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMG-007
Description: Subcutaneous injection of IMG-007
Study NCT06304740 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Subcutaneous Injection of Placebo
Study NCT06338215 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Moderate Alcohol Drinking Pattern
Description: Remotely Intensive intervention by specialized coaches (psychologists, dietitians, and other health professionals) to promote a behavior change on alcohol consumption. Repeated quarterly small group sessions and periodical personal interviews and educational videos, during up to 4 years with 1 contact every 3 months.~Goals of intervention:~1. moderate consumption (7 or less drinks/wk for women, 14 or less drinks/wk for men) of red wine (a drink=150 ml).~2. always during meals~3. spread out throughout the whole week, and~4. avoidance of binge-drinking episodes. No participant will be invited to start or increase his/her alcohol intake.
Study NCT06338215 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Moderate Alcohol Drinking Pattern
Description: Remotely Intensive intervention by specialized coaches (psychologists, dietitians, and other health professionals) to promote a behavior change on alcohol consumption. Repeated quarterly small group sessions and periodical personal interviews and educational videos, during up to 4 years with 1 contact every 3 months.~Goals of intervention:~1. moderate consumption (7 or less drinks/wk for women, 14 or less drinks/wk for men) of red wine (a drink=150 ml).~2. always during meals~3. spread out throughout the whole week, and~4. avoidance of binge-drinking episodes. No participant will be invited to start or increase his/her alcohol intake.
Study NCT06338215 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Abstention
Description: Remotely Intensive intervention by specialized coaches (psychologists, dietitians, and other health professionals) to promote a behavior change on alcohol consumption. Repeated quarterly small group sessions and periodical personal interviews and educational videos, during up to 4 years with 1 contact every 3 months.~Goals of intervention:~Abstention. Message of 0 alcohol.
Study NCT06338215 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Abstention
Description: Remotely Intensive intervention by specialized coaches (psychologists, dietitians, and other health professionals) to promote a behavior change on alcohol consumption. Repeated quarterly small group sessions and periodical personal interviews and educational videos, during up to 4 years with 1 contact every 3 months.~Goals of intervention:~Abstention. Message of 0 alcohol.
Study NCT05276011 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: TG-C
Description: 2 mL injection of non-transduced human chondrocytes and irradiated transduced human GP2-293 cells expressing TGF-B1.
Study NCT05276011 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Control
Description: 2 mL normal saline injection
Study NCT06274710 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ODYSSEE-KH
Description: Automated digital counselling program
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: decitabine
Description: Solution for intravenous infusion
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: spartalizumab
Description: Solution for intravenous infusion
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sabatolimab
Description: Solution for intravenous infusion
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: azacitidine
Description: Solution for subcutaneous injection or intravenous infusion
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: venetoclax
Description: Tablet for oral administration
Study NCT05201066 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INQOVI (oral decitabine)
Description: Tablet for oral administration. HMA = azactidine or decitabine INQOVI = decitabine (oral)
Study NCT05701722 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flourish HEC Vaginal Care System
Description: BioNourish, a component of the Flourish HEC system, is a class II medical device. In addition to BioNourish, the system includes Balance intimate wash and BiopHresh homeopathic vaginal suppository with probiotics. All products are available over the counter and have been on the market for several years.
Study NCT05576441 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: volume stable collagen matrix
Description: Volume stable collagen matrix will be placed at recipient site and suturing will be done with a 5-0 vicryl suture.
Study NCT05576441 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: subepithelial connective tissue graft
Description: SCTG will be harvested from donor site as per the requirement and will be placed at the recipient and suturing will be done with 5-0 vicryl suture.
Study NCT05686915 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MARS MRI
Description: metal artifact reduction sequence (MARS) MRI to assess for fluid collections, ATLRs or other abnormalities
Study NCT05686915 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Titanium Labs
Description: Labs to look at titanium levels in blood
Study NCT05686915 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cobalt Labs
Description: Labs to look at cobalt levels in blood
Study NCT05686915 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Chromium Labs
Description: Labs to look at chromium levels in blood
Study NCT06420102 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biophysical and biochemical skin assessment
Description: Measurements are taken from the skin surface including transepidermal water loss, skin hydration and pH. In addition, non-invasive biofluid (sebum) is sampled from the skin to profile local inflammation. Skin surface cells were also stripped to assess corneocyte properties over the pressure ulcer and surrounding healthy skin.
Study NCT04837521 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Unified Protocol
Description: Five session psychotherapy
Study NCT05046977 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Single osteotomy
Description: Single tibial osteotomy
Study NCT05046977 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Double Osteotomy
Description: Double Tibial Osteotomy
Study NCT05199896 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral protocol
Description: A touch sensitive computer screen either displaying a downscaled (45cm long) image of the rod (for the sighted), or supporting a same sized wooden rod (for the blind), will be placed on the table in front of the participant to record their localization performance. They will be instructed to use their left index fingertip to indicate on the image of the screen (for sighted) or on the wooden rod (for the blind) the position where they have felt the touch provided to the 90 cm long they held in their right dominant hand. Participants will wear a headset playing white noise to prevent any auditory localization cues when the long rod will be touched. The rod will be touched by a computer controlled solenoid. Thus, participants will respond with a hand gesture on the image or rod and will be asked to validate the position by pressing a foot-pedal with their left foot.
Study NCT05199896 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EEG protocol
Description: The EEG protocol will be similar as the behavioral one described above, with the distinction of taking place in two separate sessions: one where the rod are touched, and one where their hand is touched. The participant will hold a rod in each hand and he will have to indicate on which rod he felt the touch.~Additionally electrophysiological responses will be continuously recorded using a 65 channel ActiCap system (Brain Products).
Study NCT05199896 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: fMRI protocol
Description: The same behavioral task and procedures of the behavioral protocol described above will be applied, adapted to take into account the constraints posed by the magnetic environment of the MR scanner. The participant will be placed on the scanner bed and provided with earphones that will both protect against the noise of the machine (80dB) and ensure a continuous communication with the participant.~During the fMRI sessions, the participant will solve the same rod localization behavioral task while we will record brain activations by measuring the brain oxygen level dependent signal via Echo Planar Imaging sequences. We will use an MRI compatible tactile stimulator to touch the hand-held rod and participants location judgement will be recorded by using an MRI-compatible tablet, positioned on their abdomen, where the participant will have to indicate the judged position.
Study NCT05306236 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: LLL therapy , postural correction ex
Description: study group: will receive low level laser therapy 2 sessions per week for 6 weeks in addition to posture correction exercises.~control group: will be treated by posture correction ex only.
Study NCT05570370 — intervention group
Intervention type: OTHER
Intervention: This is an observational study
Description: This is an observational study
Study NCT05495919 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Control
Description: No intervention was perfomed to reduce anxiety in control group
Study NCT05495919 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: video interaction
Description: Before the training, educational materials were given to the students, and they were discussed with the students in the lesson.
Study NCT05495919 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: flipped training
Description: Before the training, the students took videos and during the lesson, the videos were evaluated and feedback was given.
Study NCT05858801 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PRIMUS
Description: PRIMUS system
Study NCT05135923 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Randomized, controlled trial (RCT) with parallel arms and double blinded
Description: Experiment group receive optimized gluten free products (high in fiber and whole grain) compared to comparable benchmark gluten free products (control group).
Study NCT05135923 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Randomized, controlled trial (RCT) with parallel arms and double blinded
Description: Experiment group receive optimized gluten free products (high in fiber and whole grain) compared to comparable benchmark gluten free products (control group).
Study NCT05475496 — intervention group
Intervention type: OTHER
Intervention: Measurements of quality of life and burnout
Description: WHOQOL-Bref questionnaire to assess the health related quality of life of the elderly cardiac patients. WHOQOL-Bref assesses Physical health (7 items), Psychological health (6 items), Social relationships (3 items) and the environment ( 8 items ), in addition to two items asking about overall perception of life and general health. Items are rated on a 5 point ordinal scale, domain scores are scaled in a positive direction (i.e. higher scores denote higher quality of life).~Maslach Burnout Inventory questionnaire to measure burnout among caregivers, it includes 3 components: emotional exhaustion (9 items), depersonalization(5items) and personal accomplishment(8 items).
Study NCT04927338 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BacoMind® (Bacopa monnieri standardized extract)
Description: BacoMind® (Bacopa monnieri standardized extract) 300 mg daily capsule.
Study NCT04927338 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Daily placebo capsule identical in size, color, and shape to that of the Bacopa capsules.
Study NCT04868253 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EMB-01
Description: EMB-001 is a proprietary combination of metyrapone (a cortisol synthesis inhibitor) and oxazepam (a short to medium acting benzodiazepine).
Study NCT05884983 — intervention group
Intervention type: PROCEDURE
Intervention: participants will undergo dual-energy CT and endoscopy
Description: Diagnostic Test: P85-Ab,EBNA1-IgA,and VCA-IgA. Detect P85-Ab, EBNA1-IgA, VCA-IgA for all participants and select serological high-risk participants DiagnosticTest: dual-energy CT, endoscopy and biopsy. serological high-risk participants will refer to dual-energy CT, endoscopy and biospy
Study NCT05816577 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: EcN Colibactin knockout
Description: E coli Nissle strain with ClbP-gene removed and therefore not producing colibactin
Study NCT05816577 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: E Coli Nissle
Description: E Coli wildtype strain
Study NCT05727033 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Participatory teaching group
Description: The intervention will be called FEDE-ITS® methodology. This methodology is self-designed and self-developed and draws on previous work in equivalent populations. It is based on teaching in a participatory way knowledge and healthy attitudes related to the five most prevalent STIs in the province of Barcelona and Lleida, the methods to avoid contagion, and the health resources that can be consulted in case of infection, contact with an infected person or concerns. In addition, a gender perspective is incorporated to contribute to freer and more egalitarian relationships and reduce the likelihood of violence against women which develops in adolescence.~The cross-cutting themes of the training are: health, pleasure, self-esteem, knowledge-based freedom of choice, equality between people and respect for sexual freedom. Therefore, the ultimate goal is to prevent abusive power relations and macho violence.
Study NCT05727033 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Sham control group
Description: The Health and School program was implemented to promote health in schools, and for this reason the program's nurse attends annually to address problems related to sexual affective health within the curricular itinerary of each school, but not specifically on sexually transmitted infections or gender perspective.
Study NCT06291532 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rehabilitation with VRRS
Description: The patients underwent an experimental intervention lasting two months (9 sessions lasting about 40 minutes) integrated into the regular activity of a semi-residential center for autistic adolescents and young adults.~The proposed exercises were 2D and the patient interacted with the scenarios through the touch screen. For all participants, the tasks were the same, but difficulty and duration varied according to the needs and goals to be achieved.
Study NCT05170230 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Terlipressin
Description: intracapsular injection of Terlipressin versus Carbetocin for decreasing blood loss in women undergoing laparoscopic myomectomy
Study NCT05170230 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Terlipressin
Description: intracapsular injection of Terlipressin versus Carbetocin for decreasing blood loss in women undergoing laparoscopic myomectomy
Study NCT05808790 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Minimally invasive pulmonary metastasectomy
Description: Surgical margin is equal to tumor size, if possible The goal is a parenchymal-sparing resection
Study NCT05808790 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic ablative radiotherapy
Description: Depending on tumor location, 54 Gy in 3 fractions, 55 Gy in 5 fractions, 60 Gy in 8 fractions.
Study NCT05123391 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: External beam image guided radiotherapy
Description: Volumetric modulated arc therapy (VMAT)-Image-guided radiation therapy (IGRT)
Study NCT05264272 — intervention group
Intervention type: OTHER
Intervention: Prospective serological assays
Description: 1. Investigators will measure the levels of hemogram, AST, ALT, Bilirubine-total,Platelet, ALP, rGT, Albumin, GluAC, HBA1C, Albumin, INR, AFP, Creatinine, eGFR, HBsAg, quantitative HBsAg, anti-HBc, HBeAg, anti-HBe, HBV DNA, HBV genotype, anti-HDV, HDV RNA, and HDV RNA genotype at the enrollment of the study.~2. BMI data, and Child-Pugh score (in cirrhotic patients) at the enrollment of the study. The smoking status, alcohol, coffee and green tea consumption, diabetes, family history of HCC will be collected.
Study NCT05264272 — intervention group
Intervention type: OTHER
Intervention: Retrospective serological assays
Description: 1. Investigators will measure hemogram, AST, ALT, Bilirubine-total,Platelet, ALP, rGT, Albumin, GluAC, HBA1C, Albumin, INR, AFP, Creatinine, eGFR, HBsAg, quantitative HBsAg, anti-HBc, HBeAg, anti-HBe, HBV DNA, HBV genotype, anti-HDV, HDV RNA, HDV RNA genotype BMI data, and Child-Pugh score (in cirrhotic patients) at the enrollment of the study.~2. The smoking status, alcohol, coffee and green tea consumption, diabetes, family history of HCC will be collected.
Study NCT04885400 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: iJobs
Description: During the program, the participants will learn and exercise successful job search strategies. The web-based adaptation of the Jobs program will allow self-administration. After each session, they will receive written feedback from trainers on the platform.