AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06442943 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Multi-domain Cognitive Intervention
Description: * Cognitive rehabilitation includes home-based exercise, three times per week, for 30 minutes each session.~  * Cognitive stimulation involves art therapy, once a week, for 90 minutes per session.~    * Cognitive training encompasses memory, attention, executive function, and visuospatial training, conducted three times per week, with each session lasting 30 minutes.~      * Health education, once a week, covering the prevention and treatment of chronic diseases in the elderly, as well as healthy lifestyles for the elderly.
Study NCT06522620 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block
Description: All nerve blocks were performed under ultrasound guidance，single supragluteal approach sciatic nerve block using a nerve stimulator, 20 ml of drug was injected around the sciatic nerve, the extent of drug diffusion was observed, the needle tip was turned into the deep surface of the gluteus maximus muscle below the deep gluteal artery and 5 ml of drug was injected, followed by a retractile canal saphenous nerve block injected with 15 ml of drug, and the difference in sensation of the posterior thighs of the bilateral thighs was measured after 15 min to ensure posterior femoral cutaneous nerve were blocked
Study NCT06522620 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Simple Sciatic and Saphenous Nerve Blocks
Description: All nerve blocks were performed under ultrasound guidance，single subgluteal approach sciatic nerve block using a nerve stimulator, with 25 ml of drug injected around the sciatic nerve, followed by a retractile canal saphenous nerve block with 15 ml of drug injection
Study NCT06513871 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Social perception tasks
Description: social perception tasks
Study NCT05246592 — intervention group
Intervention type: PROCEDURE
Intervention: Branches Sparing
Description: The patients will undergo axillary lymph node dissection with preserved axillary vein branches
Study NCT05246592 — intervention group
Intervention type: PROCEDURE
Intervention: None Branches Sparing
Description: The patients will undergo axillary lymph node dissection without preserved axillary vein branches
Study NCT05561478 — intervention group
Intervention type: DEVICE
Intervention: Implantation of Synthesis Plus IOL (control device)
Description: Synthesis Plus IOLs are indicated for primary implantation for the visual correction of aphakia in adult patients.
Study NCT05561478 — intervention group
Intervention type: DEVICE
Intervention: Implantation of Synthesis Plus Toric IOL (investigational device)
Description: Synthesis Plus Toric IOLs are indicated for primary implantation for the visual correction of aphakia in adult patients with pre-existing astigmatism.
Study NCT05138757 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prebiotic
Description: A prebiotic is a purified fiber of plant origin that has digestive health benefits by fostering the growth of beneficial microbes.
Study NCT05138757 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A placebo is a substance that has no therapeutic effects used as a control while testing new drugs.
Study NCT05855798 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Bupivacain
Description: Bupivacaine is a local anesthetic agent commonly used in ESP block.
Study NCT05855798 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Magnesium sulfate
Description: Magnesium is an adjuvant agent that can be added to the local anesthetic agent to increase analgesic effectiveness..
Study NCT05855798 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ketamine Hydrochloride
Description: Ketamine Hydrochloride is an also adjuvant agent that can be added to the local anesthetic to increase analgesic effectiveness.
Study NCT04895839 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient Empowerment Program
Description: The 6 months at home program focuses on aerobic and strength training, pelvic floor muscle exercises, meditation, social connection, and overall healthy lifestyle practices supported with daily text message/email reminders. The aerobic (5 times/week) and strength (2 times/week) program will comprise of a single 30-minute session daily and will be individualized to each participant. Pelvic floor muscle training will include three, 10-minute sessions and mediation for 10 minutes daily. Intimacy and Connection component of PC-PEP consists of engaging in at least one form of intimacy practice prescribed, per day. Social connection will be fostered by pairing participants up with peers from the study. To encourage program compliance, study participants will receive 3 daily reminders to do their pelvic floor muscle exercises per day plus an additional motivational email daily containing helpful tips.
Study NCT05902910 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: LUNA-EMG Robot
Description: During phase B, patients will benefit from functional rehabilitation of their upper limbs and from 30mn of training assisted by the LUMA-EMG robot.
Study NCT05636748 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 18F-GP1 PET/CT
Description: Patient will receive 1 18F-GP1 PET/CT
Study NCT05636748 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Agitated Contrast Echocardiogram
Description: Agitated saline and ultrasound contrast will be performed to assess for intracardiac shunts and left ventricular thrombus.
Study NCT05636748 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: MRI Head
Description: Where necessary, if the CT head is normal or the clinical diagnosis of a stroke is not definite, a research MRI head will be undertaken if this has not already been performed as part of standard care.
Study NCT05636748 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: ECG Monitoring
Description: All patients who do not have evidence of atrial fibrillation or atrial flutter on their 12-lead ECG will undergo an ECG Holter monitor for up to 7 days. This will be part of their standard care. If this has not been arranged by the usual care team this will be performed as a research procedure.
Study NCT06226740 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Single Visit Non Surgical Root Canal Treatment Protocol
Description: The current study aimed to compare the effects of different obturation techniques on postoperative pain level and radiographic healing in non-surgical endodontic treatment applied in a single visit in teeth with single root canal and apical periodontitis.
Study NCT05576259 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: oVRcome phone app with headset
Description: The intervention oVRcome is self-help VRET for social anxiety, that is delivered through a smartphone application (app) in combination with headset that holds the smartphone and uses 360º video. oVRcome includes 6 modules of psychoeducation, relaxation, mindfulness, cognitive techniques, exposure through VR, and a relapse prevention module which are aimed to be completed weekly.
Study NCT06021171 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially hydrolyzed guar gum + bifidobacterium lactis
Description: Synbiotic Supplement: Contains 5 grams of prebiotic fiber (Sunfiber®) and 8 billion active probiotics (Bifidobacterium lactis).
Study NCT06021171 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Partially hydrolyzed guar gum
Description: 5 g Partially hydrolyzed guar gum
Study NCT06021171 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Maltodextrin
Description: 5 g Maltodextrin
Study NCT04705129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanubrutinib
Description: 160mg Bid, D1-21, po
Study NCT04705129 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tislelizumab
Description: 200mg, D1, ivgtt
Study NCT06238518 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Intravascular Lithotripsy
Description: The size of the IVL balloon catheter is selected in a 1:1 ratio to the distal reference vessel diameter. The balloon catheter is then inflated to 4 atm, and 10 impulses are delivered. Subsequently, the balloon is inflated to 8 atm and then deflated to re-establish blood flow. Up to 100 impulses can be delivered, and the balloon can be repositioned within the lesion. In cases involving multiple lesions with different reference vessel diameters, various sizes of IVL balloons may be employed. If the IVL balloon catheter is unable to pass through the lesion, pre-dilatation can be performed using a smaller diameter noncompliant balloon or rotational atherectomy.
Study NCT06238518 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Conventional lesion preparation strategy
Description: Conventional lesion preparation strategy includes the use of Compliant, noncompliant, cutting, or scoring balloons, Excimer laser coronary atherectomy, or Rotational atherectomy at the discretion of the operator.
Study NCT06238518 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional lesion preparation strategy
Description: Conventional lesion preparation strategy includes the use of Compliant, noncompliant, cutting, or scoring balloons, Excimer laser coronary atherectomy, or Rotational atherectomy at the discretion of the operator.
Study NCT04987736 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: RT-PCR
Description: COVID 19 diagonostic test
Study NCT05111054 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Exercise
Description: Acute leg-based resistance exercise bout (3 sets performed to volitional failure on leg extension and leg curl machines)
Study NCT05111054 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance Exercise
Description: Acute leg-based resistance exercise bout (3 sets performed to volitional failure on leg extension and leg curl machines)
Study NCT06520800 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treatment and handling obesity-related comorbidities in adolescents through exercise
Description: Tailor-made, one-to-one, physical exercise program
Study NCT05105451 — intervention group
Intervention type: OTHER
Intervention: Collecting clinical data, EGG，arterial blood gas data and venous blood sample
Description: Collecting clinical data(before induction of anesthesia and first day after surgery), EGG（first day after surgery），arterial blood gas data(before induction of anesthesia and first day after surgery) and venous blood sample （before induction of anesthesia and first day, third day and 7th day after surgery）
Study NCT05773729 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: BD211
Description: Genetically modified CD34+ autologous stem cells were transfused intravenously with single dosing.
Study NCT04232358 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Corticosteroid injection
Description: Corticosteroid injections are administered ultrasound guided in the bursa adjacent to the achilles tendon insertion every 4 weeks until symptoms resolve with at maximum of 3 injections.
Study NCT05361525 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: modified saldhana's technique
Description: tummy tuck with anatomic definition using liposuction
Study NCT05361525 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Traditional abdominoplasty
Description: uses the traditional technique of abdominoplasty with liposuction with v-shaped dissection till the coastal margin
Study NCT04897906 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education Group
Description: Mother care, newborn care and breastfeeding education will be provided to pregnant women in the third trimester of pregnancy.
Study NCT05406076 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: oral motor therapy
Description: Rigorous Chinese language oral motor therapy, including treatment of oral perceptual disorders and treatment of oral motor disorders. The treatment follows three basic principles: a combination of basic training and specific treatment; a combination of self-help and assisted treatment; and a combination of exercises, cues, and stimulation techniques. 30-40 min/session, 1 session/day, 5 sessions/week.
Study NCT05406076 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: ABA
Description: The mainstream ASD intervention approach with evidence-based support is currently recognized worldwide. Treatment follows the operational core principles of ABA, which are to establish learning goals based on the child's ability level, design teaching situations and select reinforcers for them, change the child's behavior problems with operational constraints, and to eliminate or improve problem behaviors through appropriate interventions to shape new adaptive behaviors. The training time is at least 20 hours per week.
Study NCT05727969 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Dexmedetomidine at a a rate of 0.5 μg/kg/hour will be infused with induction of anesthesia.
Study NCT05727969 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lactated Ringer
Description: Lactated ringer solution at a a rate of 0.5 μg/kg/hour will be infused with induction of anesthesia.
Study NCT05727969 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Hypospadias
Description: Children who will undergone hypospadias surgery
Study NCT05727969 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hypospadias
Description: Children who will undergone hypospadias surgery
Study NCT05727969 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Surgical pleth index
Description: The SPI value will be measured using Datex-Ohmeda (GE Healthcare,Madison,WI 53707-7550 USA) monitoring system.
Study NCT05727969 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Surgical pleth index
Description: The SPI value will be measured using Datex-Ohmeda (GE Healthcare,Madison,WI 53707-7550 USA) monitoring system.
Study NCT04806217 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Theory of Mind
Description: Patients will be submitted to different neuropsychological tests used in routine and the non-verbal false belief task through in the Theory of Mind
Study NCT04232358 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Local anesthesia injections
Description: Local anesthesia injections are administered ultrasound guided in the bursa adjacent to the achilles tendon insertion every 4 weeks until symptoms resolve with at maximum of 3 injections.
Study NCT06473181 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Core stability exercises
Description: Exercises applied to trunk , pelvis and abdomen to improve ability to stand , walk and balance.
Study NCT04906811 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: AuraGen 1-2-3 with AuraClens system (BK190433)
Description: Fat grafting to the breast in patients undergoing an aesthetic procedure without a breast implant. Device used: AuraGen 1-2-3 with AuraClens system
Study NCT04906811 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Revolve System (K120902)
Description: Fat grafting to the breast in patients undergoing an aesthetic procedure without a breast implant. Device used: Revolve System
Study NCT05584514 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sentence Stimulus
Description: The sentences are designed such that a specific target word is either (a) Plausible (normal), (b) a semantic pragmatic violation, or (c) a morpho-syntactic violation. Example: e.g., Every morning at breakfast, the boys would (A: EAT)/ (B.PLANT )/ (C. EATS ) eggs...
Study NCT05584514 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Auditory Noise
Description: The sentences will be presented either A) in quiet, or B) with speech- shaped stationary background noise presented 3dB below the speech.
Study NCT05894109 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: zinc citrate 50 mg
Description: will take zinc citrate 4 days before and 1 week after botulinum toxin injection
Study NCT05894109 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo Microcrystalline Cellulose
Description: will take placebo 4 days before and 1 week after botulinum toxin injection
Study NCT05686603 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece
Description: Picosecond laser is a novel technology characterized by ultra-short, picosecond pulse duration which can be effective for many skin conditions, such as pigmentation, photoaging and wrinkles reduction. When combined with micro-lens array (MLA) optics, high-intensity, micro-injury zones can be generated in the epidermis and dermis, causing optical breakdown of surrounding tissue and stimulating of dermal remodeling with mild side-effects. Previous studies had showed the picosecond lasers with MLA afforded better or similar clinical outcomes as well as fewer side-effects in treating acne scar than non-ablative lasers.
Study NCT05686603 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: a ablative fractional 2940-nm Er:YAG laser
Description: 2940-nm erbium yttrium aluminum garnet (Er:YAG) laser is one of the most commonly used treatments for atrophic acne scars, which can remove the damage tissue of the scars and allow collagen remodeling and re-epithelialization.
Study NCT05542420 — intervention group
Intervention type: OTHER
Intervention: No treatment given
Description: The study will be based on data already recorded in the medical record
Study NCT04243564 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Supraglottic device (SGD)
Description: Positioning of SGD as temporary ventilatory device before tracheal intubation
Study NCT05208177 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SHR-1802＋camrelizumab + famitinib
Description: SHR-1802 for injection，q3w； Camrelizumab for injection, q3w; Famitinib malate capsules, qd.
Study NCT05354180 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: navicular mobilization
Description: Plantar glide combined with rotation of navicular bone against the talus The glide will be given in 20 repetitions of 3 sets, for 5 days a week
Study NCT05354180 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rigid tapping
Description: A non-elastic zinc oxide sports tape will be applied to patients. Patient will be advised to protect the tape from getting wet.~Tape will be changed on every 3rd day (48 hours) on Wednesday and Friday.
Study NCT05354180 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Navicular Mobilization and Rigid Taping
Description: Plantar glide combined with rotation of navicular bone against the talus The glide will be given in 20 repetitions of 3 sets, for 5 days a week.~A non-elastic zinc oxide sports tape will be applied to patients. Patient will be advised to protect the tape from getting wet.~Tape will be changed on every 3rd day (48 hours) on Wednesday and Friday.
Study NCT06288997 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active transcranial alternating current stimulation
Description: Hi-tACS with a current level of 15mA with a patented frequency of 77.5Hz.
Study NCT06288997 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham transcranial alternating current stimulation
Description: The device for the sham group has the same appearance and technical settings as the one used in the active group, designed to produce similar sensations on the scalp, but without effective penetration of the electric field into the brain.
Study NCT05714410 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: PHGG
Description: PHGG
Study NCT05714410 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: PHGG
Description: PHGG
Study NCT05893186 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Deep Brain Stimulation, STN
Description: DBS of the STN, within FDA-approved limits and labeling, for symptoms of PD
Study NCT05893186 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: GP Deep Brain Stimulation
Description: PD with GP DBS, within FDA-approved limits and labeling, for symptoms of PD.
Study NCT06583876 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Coriofix System
Description: Treatment of functional mitral regurgitation by reducing the mitral valve annular area through ablation of the posterior annulus.
Study NCT05804136 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Duramesh
Description: Laparotomy closure with Duramesh
Study NCT05804136 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Polydioxanone suture
Description: Laparotomy closure with standard PDS
Study NCT06122831 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQ05105 Tablets
Description: TQ05105 Tablets is a Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) Inhibitor.
Study NCT06122831 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TQB3617 Capsules
Description: TQB3617 Capsules is a Bromodomain and Extra-Terminal (BET) Inhibitor
Study NCT06166992 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 1291583
Description: BI 1291583
Study NCT06166992 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]-BI 1291583
Description: \[14C\]-BI 1291583
Study NCT05731986 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Orthostatic challenge
Description: Designed to invoke an orthostatic response. It begins with the participants lying supine on a specialized bed. The bed is then converted into a chair by raising the head of the bed by 90° and dropping the base of the bed by 90° from the knee.~This position will be maintained for 15 minutes, while hemodynamic measures are continuously recorded. Some of these sessions will be accompanied by spinal stimulation.