AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06040138 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: End expiratory occlusion maneuver
Description: An end expiratory occlusion maneuver will be performed during pressure support ventilation in patients with prolonged weaning.
Study NCT05057078 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: mindfulness-based stress reduction program
Description: groups of 10 people will be formed among the patients included in the mindfulness program group. A mindfulness-based stress reduction program will be done once a week for eight weeks and will take approximately 60-120 minutes. A plan will be made with the patients for the day and time of the session. During this process, no application will be made to the control group. Meetings will be held as an online session via Zoom Video Communications.
Study NCT06599684 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: INV-102
Description: 0.7% Ophthalmic Solution
Study NCT05186493 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: robot-assisted total pelvic exenteration
Description: Patients with locally advanced pelvic cancer that require pelvic exenteration considered eligble, are operated minimmally invasive robot-assisted
Study NCT06650137 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: diaphragmatic ultrasound
Description: The examination is performed with a phased array probe, also known as a cardiac probe. The technique used will be that described and validated in anterior studies: the patient is in the Fowler position: half-seated, at an angle of around 45 degrees. The patient is ventilating spontaneously, and no participation is required. The probe is positioned in the sub-costal region between the mid-clavicular and anterior axillary line on the right, and between the anterior and middle axillary line in the sub- or intercostal region on the left. The liver is used as an acoustic window for the right hemi-diaphragm. The probe is oriented medially, cranially and dorsally.~The operator switches to time-motion (TM) mode when an angle of over 70° is achieved between the upper part of the diaphragm and the analysis axis in the most cephalic part of the diaphragm. The image is frozen when 6 respiratory cycles have been measured.
Study NCT05756868 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time restricted feeding
Description: In the time-restricted nutrition intervention, the first meal is scheduled at 10:00 and the last meal at 18:00 (ad libitum). Eating for 8 hours and fasting for 16 hours are targeted.
Study NCT04906473 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KY100001
Description: KY100001; Tablet; Oral route; Dose escalation and dose extension
Study NCT05744531 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-based Parenting Education based on the information -Motivation-Behavioral Skills (IMB) Model
Description: Internet-based Parenting Education based on the information -Motivation-Behavioral Skills (IMB) Model
Study NCT06012344 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: post facilitation stretch
Description: PFS Post-Facilitation Stretch Participants in this arm received the intervention of post-facilitation stretch technique. Post-facilitation stretch involves the application of manual stretching techniques to the targeted muscles after a facilitation phase, which aims to enhance muscle extensibility. The participants underwent a standardized post-facilitation stretch protocol focusing on the hamstring muscles.
Study NCT06012344 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: post isometric relaxation
Description: Participants in this arm of the study received the intervention of post-isometric relaxation technique. Post-isometric relaxation involves the application of isometric contraction followed by a relaxation phase to promote muscle lengthening and improve flexibility. The participants underwent a standardized post-isometric relaxation protocol targeting the hamstring muscles.
Study NCT06012344 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: hamstring nordic lower
Description: Participants in this arm received the intervention of hamstring Nordic lower exercise. The hamstring Nordic lower exercise is a challenging eccentric exercise that specifically targets the hamstring muscles. Participants performed the exercise under supervision and followed a standardized protocol for the number of repetitions, sets, and rest intervals.
Study NCT05643703 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Suture method
Description: One-layered Suture: Single layer intermittent suture; Two-layered Suture:Single layer intermittent suture plus U type reinforcement stitching
Study NCT06209424 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Habitual Activity
Description: Participants will maintain habitual levels of physical activity (inclusive of structured physical activity).
Study NCT06209424 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Step-Reduction
Description: Participants will be required to reduce their daily step-counts to \<2,000 steps/day. Further, they will be required to refrain from structured physical activity.
Study NCT06529653 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: autogenous bone wedge
Description: autogenous bone block harvested from chin and adjusted to be wedged intercortical in split ridge
Study NCT04870801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Respirogen Micro-Oxygen
Description: Enteral (rectal) delivery of Respirogen Micro-Oxygen
Study NCT05808725 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine Freeze-Dried Powder for Oral Solution 5 mg
Description: Amlodipine Oral Solution 5 mg is given to T1 Fasting and T2 Fed
Study NCT05808725 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Norvasc 5 mg tablets of Pfizer Labs
Description: Norvasc 5 mg is given to R Fasting
Study NCT06060457 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 0.9% sodium chloride (normal saline) injection
Study NCT06060457 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: mRNA-1345
Description: Suspension for injection
Study NCT06060457 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Fluzone HD
Description: Suspension for injection
Study NCT06608459 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PEX010-Assisted Therapy
Description: The investigational medicinal product PEX010 is a capsule for oral administration that contains the drug substance PYEX.
Study NCT06668077 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: iTBS of the left DLPFC
Description: Participants will receive a 3 minutes active theta burst transcranial magnetic stimulation (iTBS) of the DLPFC of the left hemisphere while not performing any other task
Study NCT06668077 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: iTBS of the left DLPFC
Description: Participants will receive a 3 minutes active theta burst transcranial magnetic stimulation (iTBS) of the DLPFC of the left hemisphere while not performing any other task
Study NCT06668077 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: iTBS of the vertex
Description: Participants will receive a 3 minutes active theta burst transcranial magnetic stimulation (iTBS) of the vertex while not performing any other task
Study NCT06668077 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Inhibitory control training
Description: Computerized cognitive training. Participants will perform the task of the FoodT app for 10 minutes during two weeks (taking advantage of time of maximum brain potentiation after the iTBS, Rossi et al., 2009). Images of food and non-food appear on the left, right or centre of the smart phone screen and participants must touch it (or not, depending on the cue) with their index finger as quickly as possible. Participants earn points for correct tap responses and lose points for incorrect tap responses. If the image has a green border around it, participants must tap the image and win 1 point. But if the image has a red border around it, participants must inhibit the tapping response, otherwise 1 point will be lost. Participants must respond as quickly and accurately as possible. Pictures of healthy and unhealthy foods are always paired with the Go and the No-Go signal, respectively. Non-food images are paired 50% of the time with the Go and the No-Go signal
Study NCT06519981 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HRS-9231or matching placebo
Description: HRS-9231 injection or matching placebo will be administered through IV injection.
Study NCT06209424 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Resistance Exercise
Description: Participants will undergo a 50-minute resistance exercise protocol, which includes multiple sets of different exercises using weights. Each set will consist of 10 repetitions at 75% of their 1 repetition maximum (1RM). The exercises include bench press superset with lat pulldowns, overhead press superset with seated cable rows, leg press, and leg extensions with 90s rest in between sets. Before the exercise protocol, there will be a standardized 10-minute warm-up that involves cycling, leg swings, arm circles, bodyweight squats, and bench push-ups
Study NCT04586010 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fenebrutinib
Description: Participants will receive fenebrutinib.
Study NCT04586010 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Teriflunomide
Description: Participants will receive teriflunomide.
Study NCT04586010 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: Participants will receive teriflunomide-matching placebo or fenebrutinib-matching placebo.
Study NCT04586010 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: Participants will receive teriflunomide-matching placebo or fenebrutinib-matching placebo.
Study NCT05430074 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: HM Cast
Description: Subjects assigned to this arm will be treated via cast immobilisation with the use of HM casts.
Study NCT05430074 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Fibreglass Cast
Description: Subjects assigned to this arm will be treated via cast immobilisation with the use of Fibreglass casts.
Study NCT06095492 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin 25 MG
Description: Patient will get Empagliflozin 25
Study NCT06095492 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Linagliptin
Description: linagliptin 5 mg once a day
Study NCT06632418 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RhPDGF-BB
Description: 0.3 mg/mL rhPDGF-BB
Study NCT04320602 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Eculizumab
Description: Participants must have been prescribed and be receiving a stable dose of eculizumab 1200 milligrams (mg) every 2 weeks (q2w) for at least 3 months prior to the Screening Period. During the Screening Period, participants will continue to receive eculizumab 1200 mg q2w.
Study NCT04320602 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ravulizumab
Description: During the Treatment Period, participants will receive a loading dose of ravulizumab on Day 1, followed by maintenance doses on Day 15 and every 8 weeks, administered by intravenous infusion. Ravulizumab loading and maintenance doses will be based on participants' body weight per approved dose regimen.
Study NCT06715787 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: FEAST Perinatal Support Program
Description: The intervention will include the core perinatal support program (PSP) with $15 weekly grocery gift cards for healthful food (fruit, vegetables, whole grains), The PSP will be completed during weekly group sessions over 16 weeks. The core PSP includes the two primary behavior change techniques: group-based nutrition education based on current United States Department of Agriculture (USDA) national guidelines for pregnant individuals and guided group sharing and engagement.
Study NCT06721741 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nusmile bioflex crowns
Description: The Bioflex crown is a new synthetic crown that has been introduced in pediatric practice. This crown is believed to offer better adaptation, durability, and ease of handling, along with improved aesthetic properties when compared to conventional crowns
Study NCT06721741 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Stainless steel crowns
Description: Preformed metal crowns are a popular and affordable option as a treatment for dental caries. They offer full crown coverage and help to prevent recurrent caries. However, their aesthetic limitation is a notable drawback
Study NCT06720987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: KQB365
Description: Intravenous KQB365
Study NCT06720987 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cetuximab
Description: Intravenous cetuximab
Study NCT06721611 — intervention group
Intervention type: DEVICE
Intervention: Optical Blood Pressure Monitoring Device (Aktiia G1)
Description: Non-hypertensive Nucor employees that accept to wear an optical blood pressure monitoring device (Aktiia 24/7 device) to screen for and identify potential undiagnosed hypertension.~100 participants. Each participant will wear the device continuously for 28 days.
Study NCT06721325 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: THERAPEUTIC EDUCATION IN PHYSIOTHERAPY
Description: Educational program of physiotherapy for women survivors of sexual violence and female genital mutilation.
Study NCT06721325 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Psychotherapy and legal advice
Description: Usual psychological and legal advice therapy for this population
Study NCT06721325 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychotherapy and legal advice
Description: Usual psychological and legal advice therapy for this population
Study NCT06719830 — intervention group
Intervention type: PROCEDURE
Intervention: Radiofrequency ablation
Description: Radiofrequency ablation of the septal accessory pathway
Study NCT06719843 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACT-based intervention
Description: Participants in the intervention group will receive the face-to-face ACT-based intervention weekly for 4 weeks (each session lasting approximately 90 minutes), with each group consisting of 6-8 older adults. The intervention consists of 4 sessions:~Session 1 (acceptance and cognitive fusion) Session 2 (contact with the present moment and self-as-context) Session 3 (values) Session 3 (committed action)
Study NCT04947215 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: stress biomarkers
Description: used to estimate the reference values of putative biomarkers of birth stress such asCTnT, CTnI, copeptin, NT-proBNP and hs-CRP in the cord blood of full term neonates
Study NCT05241197 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low Load Training with Blood Flow Restriction
Description: A 12-cm-wide pneumatic nylon tourniquet will be proximally positioned with a snug fit on each thigh. Previously, arterial occlusion pressure (AOP) will be determined using a handheld Doppler Ultrasound in a standing position for each participant. For training routines, cuff pressure will be set to 50% of each individual´s AOP and will be keep inflated during the entire session including the interset rest period of 1 minute. Between the two exercises, the cuff will be deflated for 3 minutes.
Study NCT05976217 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: 100 mg daily by mouth for 3 weeks This drug inhibits a protein (Bcl-2) that protects cells from undergoing programmed cell death.
Study NCT04793438 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motive-specific intervention
Description: Three appointments are made with the patients of the intervention group within two weeks. With an adaptation of the Autobiographical Memory Test (AMT) participants will be asked to recall events from the past and to imagine future events. The time frame of 45 minutes for each intervention must be strictly adhered to. Patients are additionally asked to complete tasks between the sessions. All appointments take place in the Psychiatric University Hospital directly on the ward.
Study NCT04793438 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Supportive conversations
Description: Since we want to check whether the patients benefit from the specific intervention and not only from getting more speaking time, patients without the motive-specific intervention should also be given three sessions, in which no intervention takes place. They will be carried out in the sense of supportive conversations (i.e. conversations that do not follow a specific psychotherapy concept). All appointments take place in the Psychiatric University Hospital directly on the ward.
Study NCT06253754 — intervention group
Intervention type: OTHER
Intervention: MRI examination
Description: All included subjects will be examined with MRI
Study NCT05706727 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intravenous bolus dose of Mephentermine and mephentermine
Description: intravenous bolus dose of mephenteramine 6mg
Study NCT05706727 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: intravenous bolus dose of phenylephrine 50 mcg
Description: intravenous bolus dose of phenylephrine 50 mcg
Study NCT05046912 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Yoga
Description: 8 weeks of online weekly yoga or chair yoga class
Study NCT05759598 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Rehabilitation protocol + guided spontaneous breathing exercises
Description: Standard integrated metabolic rehabilitation protocol + guided spontaneous breathing exercises
Study NCT05759598 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation protocol + specific respiratory muscle training program
Description: Standard integrated metabolic rehabilitation protocol + specific respiratory muscle training program according to the protocol recently proposed by Spengler et al. (Wuthrich et al., 2015; Schaer et al., 2018), adapted according to the baseline characteristics of the respiratory function of the subjects
Study NCT05319327 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Nutritional intervention
Description: A nutritional intervention program aimed to reduce UPF consumption. Nutritional intervention will not modify basal caloric intake but will record energy intake along the intervention. Nutritional counseling will be based on nutritional educational material such as encouraged and discouraged food items, recipes, menus and food shopping lists based on unprocessed or minimally processed foods.~Total intervention will last 6 months for both groups. During the intervention phase, a monthly interview with nutritionist/dietitian is scheduled. Face-to-face interviews will be carried out in months 2 and 4. Phone interviews will be carried out in months 1, 3 and 5. In the baseline and final visits (months 0 and 6) a sample and data collection will be performed.
Study NCT05319327 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: General counseling to adhere to a healthy Mediterranean diet
Study NCT05603273 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: non-weight bearing exercise
Description: exercise on a non-weight bearing device at 50% of peak capacity, 3 days per week for 6 weeks
Study NCT05046912 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Yoga
Description: 8 weeks of online weekly yoga or chair yoga class
Study NCT05046912 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness
Description: 8 weeks of online weekly mindfulness class
Study NCT05046912 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mindfulness
Description: 8 weeks of online weekly mindfulness class
Study NCT04939831 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Total Laparoscopic or Robotic Radical Hysterectomy
Description: Radical hysterectomy with bilateral pelvic lymph node dissection is performed as standard type C RH by Q-M classification, including cardinal ligaments divided at pelvic sidewall and uterosacral ligaments divided at near the sacral origin and the upper 1/4 to 1/3 of the vagina.
Study NCT04939831 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Total Abdominal Radical Hysterectomy
Description: Radical hysterectomy with bilateral pelvic lymph node dissection is performed as standard type C RH by Q-M classification, including cardinal ligaments divided at pelvic sidewall and uterosacral ligaments divided at near the sacral origin and the upper 1/4 to 1/3 of the vagina.
Study NCT05154045 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Experimental Formula
Description: Diabetes-specific study formula
Study NCT05787210 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventiional Physiotherapy
Description: The Control group will be administered with Conventional Physiotherapy that Includes 5 minutes of trunk control training, 5 minutes walking in the hall with And without the therapist assistance, walker or crutches, and finally 5 minutes of Breathing exercises for Relaxation
Study NCT05787210 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventiional Physiotherapy
Description: The Control group will be administered with Conventional Physiotherapy that Includes 5 minutes of trunk control training, 5 minutes walking in the hall with And without the therapist assistance, walker or crutches, and finally 5 minutes of Breathing exercises for Relaxation