AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06620601 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Treatment
Description: Based on the decision aid, patient preference, and CADTH recommendations, the sleep physicians will recommend the participant to use Auto-CPAP or MAD for six months.
Study NCT06620601 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: Participants will complete eleven questionnaires: Stop-Bang, Insomnia severity index, Epworth sleepiness score (ESS), quality of life (FOSQ-10), Beck Depression Inventory (BDI), Chalder Fatigue Scale (CFQ), primary care post-traumatic stress disorder (PTSD) scale (PC-PTSD-5), Asthma control questionnaire (ACQ), OHIP-14, and Participant demographics. The RA will help the participants complete the questionnaires (\~one and a half hours in total).
Study NCT06620601 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Questionnaires
Description: Participants will complete eleven questionnaires: Stop-Bang, Insomnia severity index, Epworth sleepiness score (ESS), quality of life (FOSQ-10), Beck Depression Inventory (BDI), Chalder Fatigue Scale (CFQ), primary care post-traumatic stress disorder (PTSD) scale (PC-PTSD-5), Asthma control questionnaire (ACQ), OHIP-14, and Participant demographics. The RA will help the participants complete the questionnaires (\~one and a half hours in total).
Study NCT06619925 — intervention group
Intervention type: BEHAVIORAL
Intervention: after-school extended sports service
Description: Impact of voluntary participation in different types (e.g. outdoor physical activities, indoor physical activities, ball games, calisthenics, etc.), intensity and duration of after-school extended physical education services on children\&#39;s myopia and other physical and psychological well-being
Study NCT06619925 — intervention group
Intervention type: BEHAVIORAL
Intervention: non-after school extended sports service
Description: Students in the same grade as the exposure group but participating in after-school non-physical education extended services (e.g., homework help, static activities such as calligraphy, chess, etc.) served as a control group, aiming to maximise the control of the influence of potential factors other than physical activity on the results of the study.
Study NCT06620887 — intervention group
Intervention type: OTHER
Intervention: Evaluate the impact of HEMAGO program on maternal morbidity and mortality in sickle cell disease patients during their pregnancies.
Description: HEMAGO pregnancy monitoring is a joint consultation program between the sickle cell disease hematologist and an obstetrician. This program was implemented in April 2016 at the Croix-Rousse maternity Hospital. This program offers close, complete and personalized pregnancy monitoring for each patient with major sickle cell syndrome.~These are follow-up consultations once a month until 24 weeks then every 15 days until delivery. At each consultation, doctors evaluate a general and obstetric clinical examination. The team establishes a precise schedule adapted to each patient for pregnancy monitoring : monthly blood tests, monthly ultrasounds with maternal and fetal Doppler, adaptation of basic treatment, transfusion exchange program according to eligibility criteria, and organization of childbirth.
Study NCT06621693 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical diaphragmatic stimulation intervention
Description: It will be applied on diaphragm, 30 min per session ,3 days/week for 4 weeks at a stimulation frequency of 30 Hz, pulse width of 400 μs, the intensity was gradually increased until visible muscle contraction was observed.
Study NCT06621693 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: traditional physiotherapy program
Description: The participants will receive traditional physiotherapy ( postural drainage, percussion , diaphragmatic breathing, phase 1 cardiac Rehabilitation and balance training ) three times per week for 4 weeks
Study NCT06621693 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: traditional physiotherapy program
Description: The participants will receive traditional physiotherapy ( postural drainage, percussion , diaphragmatic breathing, phase 1 cardiac Rehabilitation and balance training ) three times per week for 4 weeks
Study NCT06621134 — intervention group
Intervention type: OTHER
Intervention: AI Chatbot
Description: Participants will be required to provide consent for randomization when they first access our system. Users can ask questions covered by the question bank, as well as specific questions not covered by the bank, through an AI chatbox. The aim is to understand the significant difference between using AI chatbots and telephone hotlines to assist parents, as well as the effectiveness of AI chatbots compared to telephone hotlines.
Study NCT06621134 — intervention group
Intervention type: OTHER
Intervention: Telephone hotline
Description: Participants will be asked to consent to randomization on their first access to our system. Users ask questions covered by the question bank and specific questions not covered by the question through a telephone hotline.
Study NCT06621030 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MIB Breath Analyzer
Description: Going through visit-specific blood glucose excursions by the administration of glucose and insulin (clamp), monitoring physiological processes, and measuring reference blood glucose values and VOC measurements in the breath using a GC IMS and the MIBs (investigational devices). Going through visit-specific blood glucose excursions by consuming a standardized meal, monitoring physiological processes, and measuring reference blood glucose values and VOC measurements in the breath using a GC-IMS and the MIBs (investigational devices) Imitating the glucose excursion from the meal excursion by infusing glucose and insulin (clamp), monitoring physiological processes, and measuring reference blood glucose values and VOC measurements in the breath using a GC-IMS and the MIBs (investigational devices).
Study NCT06623708 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SMARTCLOTH
Description: The intervention consists of using SMARTCLOTH. This device makes it possible to monitor dietary intake throughout the day and record it in a database that, through a website, allows to track it. SMARTCLOTH is a digital tablecloth consisting of a scale, several buttons and a screen. The device allows weighing the food to be consumed and recording its nutritional value (macronutrients in grams, macronutrient servings and kilocalories). The latter is achieved because SMARTCLOTH allows the patient to select to which food group the food being weighed belongs, increasing the accuracy of the nutritional estimation.
Study NCT06622382 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bariatric endoscopic antral myotomy
Description: A mucosal incision is performed using a triangle-tip knife J at the level of the incisura along the level of the greater curvature. Submucosal tunneling is then performed and stopped immediately proximal to the pylorus. Two parallel lines of partial thickness myotomy are then performed from the distal to proximal antrum using the same endoscopic knife. The myotomy is stopped approximately 2 cm distal to the mucosal incision site. Finally, the mucosal incision is closed using endoclips after haemostasis is confirmed.
Study NCT06622759 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: CTG
Description: Connective Tissue Graft has been widely used around implants to increase either the thickness of the soft tissues or the width of keratinized tissues. It is considered the gold standard for soft tissue grafting. The main drawbacks are the donor morbidity and the limit amount of intraoral donor sites. In this study it will be used in the test 1 group in order to compare its clinical results with the other groups.
Study NCT06622759 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Collagen Matrix
Description: Collagen matrix has been used in several studies in order to evaluate its clinical properties over the last years. In this study, the graft will be placed buccally at the time of implant placement in the aesthetic zone in order to assess its clinical and radiographic properties in terms of buccal bone resorption and soft tissue augmentation. Histological assessment and Patient Reported outcomes will also be evaluated.
Study NCT06622759 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Control group
Description: In the control group, the implant will be placed without any kind of soft tissue graft in order to compare this treatment modality that many clinicians apply at the clinical practice.
Study NCT06622837 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: implant overdenture
Description: With the assistance of these stereolithographic surgical guides and submerged surgical technique, 4 dental implants (IS III Active Implant, Neo BioTech) were placed in the canines and premolars regions of the maxillary arch, and 2 dental implants were placed in the canines region of the mandibular arch.
Study NCT06622057 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: D07001-Softgel Capsules
Description: D07001-softgel capsule is an oral gemcitabine.
Study NCT06622057 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo has the same excipient with D07001-softgel but without active pharmaceutical ingredients (APIs)
Study NCT06622057 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine, a fluoropyrimidine carbamate derivative, is an oral tumor activator and selective cytotoxic agent.
Study NCT06622057 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Capecitabine
Description: Capecitabine, a fluoropyrimidine carbamate derivative, is an oral tumor activator and selective cytotoxic agent.
Study NCT06621901 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: High Protein Diet
Description: Individuals will be placed on a high protein diet for 10 days.
Study NCT06621901 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal Protein Diet
Description: Individuals will be placed on a normal protein diet for 10 days.
Study NCT06622174 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Pulse radiotherapy
Description: Pulsed radiotherapy combined with PD(L)-1 inhibitors targeting 2 to 5 progressive extracranial lesions per cycle
Study NCT06624280 — intervention group
Intervention type: PROCEDURE
Intervention: single-event multilevel surgery
Description: surgical orthopedic approach where multiple deformities are corrected in one solution, often involving both lower limbs, to improve walking performance
Study NCT06623825 — intervention group
Intervention type: DEVICE
Intervention: teleconsultation by Augmented Reality smart glasses
Description: The device operated on Android 9.0 and it connected to 5G connection with a bandwidth speed 30-mbps delivering a very low latency. The device supported real time screen sharing and therefore the data were collected from smart glasses including visual and audio with real-time two-way communications. Physicians at the hospital can access the information and video via a mobile app, enabling continuous monitoring of patients. The features facilitate healthcare providers at SRRSH and medical personnel in the HAG2022 polyclinic to discuss the patient's condition, exchange, and deliberate on the pre-hospital medical examinations of the patient.
Study NCT06623825 — intervention group
Intervention type: DEVICE
Intervention: teleconsultation by two-way radio connection.
Description: adhering to the standard conventional triage process without the AR tool, only using a two-way radio connection.
Study NCT06623513 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Parecoxib Sodium
Description: Parecoxib Sodium 40 mg administered intravenously 30 minutes before the ERCP procedure.
Study NCT06623513 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Indomethacin suppository
Description: Indomethacin suppository 100 mg administered rectally 30 minutes before the ERCP procedure.
Study NCT06619977 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Analgesia nociception monitoring (ANI)
Description: Analgesia nociception index (ANI; MetroDoloris Medical Systems, Lille, France) is a noninvasive tool for monitoring the intraoperative state of the autonomic nervous system, in particular - the parasympathetic nervous system. The ANI algorithm uses data from one lead ECG trace. Heart rate variability, or the beat-to-beat alterations in heart rate, is a well-known and recognised noninvasive indicator of autonomic nervous system activity.
Study NCT05132712 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Losartan Potassium
Description: ACE inhibitor
Study NCT05132712 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: multi-vitamins
Description: placebo drug
Study NCT04776018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TAK-981
Description: TAK-981 IV infusion.
Study NCT04776018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mezagitamab
Description: Mezagitamab SC injection.
Study NCT04776018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daratumumab and Hyaluronidase-fihj
Description: Daratumumab and Hyaluronidase-fihj SC injection.
Study NCT05186636 — intervention group
Intervention type: OTHER
Intervention: KPI reports
Description: Quarterly
Study NCT05186636 — intervention group
Intervention type: OTHER
Intervention: Prescriber reports
Description: Individualized prescriber reports for acute RRT initiation patterns along with targeted education to ensure that align with best evidence-based practices
Study NCT05293873 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: autologous bone marrow-derived mononuclear cell transplantation
Description: Bm-MNC will be transplanted at baseline, and the second transplantation will be performed 6 months after the first transplantation
Study NCT05293873 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Rehabilitation therapy
Description: Rehabilitation therapy
Study NCT05293873 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rehabilitation therapy
Description: Rehabilitation therapy
Study NCT06382441 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: tele-exercise
Description: It is a prospective and pilot study of RCT. It will be a pilot to test acceptability and feasibility of a two-armed tele-exercise RCT to mitigate symptoms and improve health for breast cancer survivors. In this study, outcome assessors and data analysts will be masked from the allocation results. The pilot will recruit 24 patients and randomly assign them to an intervention group (Group A) and an active control group (Group B). All participants in both groups will continue receiving usual care from the study hospital during the study period. Additionally, those in Group A (intervention) will receive the tele-exercise (12 home-based online training sessions + 4 psychological counselling sessions), while those in Group B (active control) will receive 4 essays on exercise and health. Outcome measurements will be repeatedly performed before and after the intervention.
Study NCT04719663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Biological illness and treatment rationale
Description: Depression is described as a brain disorder and the role of monoamine, brain structures, and brain functions are reported as central mechanisms of relevance for its etiology and treatment. Biological processes are illustrated using typical charts and visualizations. Psychological influences are mentioned, but only as a byproduct of the disorder.
Study NCT04719663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psychological illness and treatment rationale
Description: Depression is described as a psychological disorder resulting from emotion regulation deficits. The suppression of emotions receives a special role in explaining depression. The psychological processes are illustrated using charts and visualizations. Biological aspects are mentioned, but only as a byproduct of the disorder.
Study NCT04719663 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Active pharmacological placebo
Description: The active placebo pill does not have direct effects on the brain. Buscopan (butylscopolamine, 10 mg daily, 1 pill in the morning) does not cross the blood-brain barrier, yet induces some smaller side effects that resemble those of antidepressants (e.g., mouth dryness, fatigue, nausea). Treatment duration is 4 weeks. The rationale is briefly explained to participants as stimulating the biological balance in humans with depression, using a well-tolerated drug similar to Buscopan, which is well-known from pain treatments.
Study NCT04719663 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Active psychological placebo
Description: Emotional writing consists of writing about emotional experiences (4 sessions, one per week, 30 minutes each). The study instructor will be present displaying standard psychotherapeutic attitudes but will not read the participant's notes. The rationale for this treatment is briefly explained as improving the dealing with emotions to achieve a psychological balance in humans with depression.
Study NCT05565274 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pentazocine plus placebo
Description: 30mg of pentazocine and 2milliLitre of injection water
Study NCT05565274 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentazocine plus placebo
Description: 30mg of pentazocine and 2milliLitre of injection water
Study NCT04937426 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Fluorescent-labeled Urease Inhibitor Marker to Detect Helicobacter Pylori
Description: Diagnostic laboratory test for detection of helicobacter pylori
Study NCT04799860 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: health promotive work-way
Description: Clinical intervention: The patient is asked to fill in a screening form with life-style related questions. The caregiver takes adequate measures according to the recommendations of the national guideline and the filled in screeing form. The caregiver documents the measures taken.~Implementation intervention as described previously: using tailored strategies to support implementation of the gudieline-based recommendations
Study NCT04856943 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Smartconsent application
Description: Patients asigned to smartconsent group will sign informed consent through a Tablet.
Study NCT04856943 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control group
Description: Patient asigned to control group will sing the informed consent in papel, as it is performed in clinical practice
Study NCT05357144 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Loyalty card program at drug shops & supply of HIVST and SRH products
Description: Consenting drug shops will receive:~* training on Malkia Klabu implementation;~* HIVST training (same as comparison drug shops);~* procedures for referring to youth-friendly HIV/SRH services;~* a monthly supply of HIVST reserved for free distribution to AGYW, with free price stickers and pre-packaged with referral information; and~* reimbursement for SRH products given to AGYW (e.g., birth control pills).
Study NCT05357144 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Comparison drug shops
Description: Consenting drug shops in the comparison arm catchment areas will have access to the Maisha Meds inventory management application system for offline digital recording of HIVST, HIVST kits earmarked for free to AGYW, guidance on HIV care referral plan to facilitate linkage to nearby health facilities for AGYW. These control drug shops will not participate in Malkia Klabu (Queen Club) program implementation.
Study NCT05189093 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Recombinant humanized anti-CD47/PD-1 bifunctional antibody HX009 injection
Description: There will be a total of 4 cohorts, each cohort will explore 1-2 dose levels, i.e. 10 mg/kg and 15 mg/kg, with an expected enrollment of 40-80 cases. The 10 mg/kg dose level will be enrolled first, the After discussion between the sponsor and the DSC, the 15 mg/kg dose level will be enrolled if necessary. Based on the DMC analysis, the no-trend cohort will be enrolled in a maximum of 10 cases (with the possibility of stopping enrollment halfway through).
Study NCT04183738 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: NRTIs
Description: In SOC arm, choice of NRTIs determined by clinician, guided by either genotypic resistance testing or use of a protocol-specified algorithm for N(t)RTI selection.~In D2N arm, NRTIs are predetermined.
Study NCT04183738 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: NRTIs
Description: In SOC arm, choice of NRTIs determined by clinician, guided by either genotypic resistance testing or use of a protocol-specified algorithm for N(t)RTI selection.~In D2N arm, NRTIs are predetermined.
Study NCT04183738 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Darunavir
Description: 800mg tablet by mouth once daily for 96 weeks.
Study NCT04183738 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Darunavir
Description: 800mg tablet by mouth once daily for 96 weeks.
Study NCT04743375 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: wound dressing application
Description: Sericin dressing with collagen or Bactigras will be used as a primary dressing for treating the STSG donor site.
Study NCT04743375 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: wound dressing application
Description: Sericin dressing with collagen or Bactigras will be used as a primary dressing for treating the STSG donor site.
Study NCT05238532 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: CT303
Description: Once a time, intravenous injection~* CT303 Starting Dose : 1.0\*10\^6 cells/kg~* CT303 Increasing Quantity Dose : 2.0\*10\^6 cells/kg
Study NCT05261932 — intervention group
Intervention type: PROCEDURE
Intervention: AI-assisted guided biopsy
Description: The surface of the adenoma was classified and identified by the AI system, and different areas of the adenoma were marked by distribution to guide the endoscopist for biopsy to obtain the poorly differentiated portion of the lesion.
Study NCT04744181 — intervention group
Intervention type: DRUG
Intervention: Ferric carboxymaltose
Description: administration of a single dose of ferric carboxymaltose in those patietns who fulfill the inclusion criteria