AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05712018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxyethyl starch coload - 5 ml/kg
Description: 5 ml/kg 6% Hydroxyethyl starch (130/0.4) coload combined with an initial infusion dose of prophylactic norepinephrine (0.025 ug/kg/min) simultaneous with spinal anesthesia. The dose administered to subsequent patients varied by increments or decrements of 0.005 ug/kg/min of prophylactic norepinephrine according to the responses of previous patients according to the up-down sequential allocation.
Study NCT05712018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydroxyethyl starch coload - 10 ml/kg
Description: 10 ml/kg 6% Hydroxyethyl starch (130/0.4) coload combined with an initial infusion dose of prophylactic norepinephrine (0.025 ug/kg/min) simultaneous with spinal anesthesia. The dose administered to subsequent patients varied by increments or decrements of 0.005 ug/kg/min of prophylactic norepinephrine according to the responses of previous patients according to the up-down sequential allocation.
Study NCT05830929 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Ovarian tissue freezing and subsequent auto-transplantation after thawing
Description: Removal of the ovarian tissue will be retrieved via laparoscopic surgery under general anesthesia. The ovarian cortical tissue obtained will be transferred on ice to the laboratory for cryopreservation. After medical treatment, if the patient would like to start a family but has experienced premature ovarian failure, she will have ovarian tissue auto-transplantation after thawing.
Study NCT04931238 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JS016
Description: Single Intravenous Injection of JS016 with a dose of 50mg/kg
Study NCT05498493 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Rehabilitation
Description: The virtual small group format will include two to five participants and one facilitator per group. The three individual sessions are distributed at the beginning, middle, and towards the end of the training program. Individual Session 1 occurs after Group Session 1. It covers orientation to the training program, including orientation to and clarification of the Participant Handbook. Individual Session 2 occurs after Group Session 5 and involves review and implementation of training strategies. Individual Session 3 occurs after Group Session 9 and covers review of learned strategies, implementation of training strategies in daily life, and review of execution, obstacles, and adjustments required for individual projects.
Study NCT05498493 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brain Health Education Program
Description: The active control group will control for non-specific effects inherent to supervised CR. Participants will receive a manualized brain health education (BHE) training program, matched with the adapted CR intervention for therapist time and homework. Once these participants complete the 12 weeks of the control intervention and undergo the post-intervention assessments, participants will be offered the 12 weeks active intervention to ensure that all study participants have the potential of benefitting from CR.
Study NCT04445792 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Pharmacogenetic testing
Description: Genetic testing of CYP2D6 and CYP2C19
Study NCT04445792 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacogenetic testing
Description: Genetic testing of CYP2D6 and CYP2C19
Study NCT04445792 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical decisions support
Description: Prescribing recommendations to the provider based on the pharmacogenetic testing results
Study NCT06329791 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AZR-MD-001
Description: AZR-MD-001 sterile ophthalmic ointment 0.5%
Study NCT06329791 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: AZR-MD-001 Vehicle
Study NCT05619159 — intervention group
Intervention type: DEVICE
Intervention: microscopic pathological evaluation
Description: description of moesin expression between endometrial hyperplasia and endometrial carcinoma
Study NCT05053061 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Application program for pulmonary rehabilitation
Description: Exercise videos for pulmonary rehabilitation
Study NCT04856527 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical therapist support
Description: Participants will receive physical therapist support to reduce postural sway variability while completing an upper limb precision aiming task in virtual reality.
Study NCT05196035 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Finerenone (Kerendia, BAY94-8862)
Description: Finerenone in different doses, treatment duration will be 180±7 days
Study NCT05196035 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo to finerenone, treatment duration will be 180±7 days
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided face to face
Description: Feedback will be provided face-to-face.
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided by electronic mail
Description: Feedback will be provided by electronic mail.
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided by researchers
Description: Feedback will be provided by researchers.
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided by authoritative bodies
Description: Feedback will be provided by authoritative bodies.
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided with peer comparision
Description: Feedback will be provided with peer comparison.
Study NCT06480487 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Feedback provided without peer comparision
Description: Feedback will be provided without peer comparision.
Study NCT05428046 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MHL intervention
Description: The current MHL intervention is a brief online intervention and comprises two modules. The first module is a short video introducing a teenage girl with bulimia nervosa. The second module is an online lecture comprising information about eating disorders including the prevalence, symptoms, type, cause, treatment, a related symptom checker, and sources of help. The above two modules are implemented in a single session lasting approximately 2 hours.
Study NCT05574946 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Anterior Cruciate Ligament Reconstruction
Description: Anterior Cruciate Ligament Reconstruction with four strand semitendinosus graft
Study NCT05574946 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anterior Cruciate Ligament Reconstruction
Description: Anterior Cruciate Ligament Reconstruction with four strand semitendinosus graft
Study NCT06607939 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ORB-021
Description: ORB-021 is dosed via IV infusion
Study NCT06609161 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tedizolid Phosphate Oral Formulation 1 (Reference)
Description: Formulation 1 (FM1) powder for oral suspension.
Study NCT06609161 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tedizolid Phosphate Oral Formulation 2 (Test)
Description: Formulation 2 (FM2) powder for oral suspension.
Study NCT06612229 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Conservative surgical treatment of liver echinococcosis, verification of occult biliary fistulas and their elimination by weaving and using medical cyanoacrylate glue
Description: In conservative surgical operations for liver echinococcosis, the biliary fistula is identified, onto which a U-shaped suture is applied, after which medical cyanoacrylate glue is applied between the suture stitches to the fibrous capsule in the fistula area and the suture threads are tied.
Study NCT04895709 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-986340
Description: Specified dose on specified days
Study NCT04895709 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BMS-936558-01
Description: Specified dose on specified days
Study NCT04895709 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Docetaxel
Description: Specified dose on specified days
Study NCT06615856 — intervention group
Intervention type: OTHER
Intervention: Questionnaire
Description: Two questionnaires will be provided to participants to complete before their routine tests (which they would already be having regardless of the study and are not affected by their participation in the study).~The questionnaires include: A Gastro-Oesophageal Reflux Symptom Questionnaire; and the ROME-IV Diagnostic IBS Module Questionnaire
Study NCT05911750 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Anal pap smear and oral swab for cytology and HPV testing
Description: Anal and oral swab sampling for HPV detection (polymerase chain reaction) and cytology
Study NCT05211063 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Saffron extract (Crocus sativus)
Description: Daily intake of one tablet for 42 days.
Study NCT05211063 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Daily intake of one tablet for 42 days.
Study NCT06678646 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Elbow ultrasound-guided surgery
Description: Percutaneous Ultrasound-Guided Release of the Lacertus Fibrosus for Median Nerve Entrapment at the Elbow
Study NCT05037773 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention targeting parental reminiscing style
Description: 8-session intervention (i.e., 1 session/week) targeting 3 main aspects of parental reminiscing: the promotion of child participation, the structure of discussions about the past and the content addressed during these discussions. Different learning techniques are used: psychoeducation, modeling and supervised practice.
Study NCT03557697 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: At the end of the study the control group will be provided with the opportunity to receive counseling videos delivered via SMS
Study NCT03557697 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: SMS Intervention
Description: Participants in the intervention group will receive SMS based video counseling which include both educational and SCT=-based behavioral content. In addition, participants will receive biweekly phone calls from study community health workers to review the video content and clarify questions, set goals, and problem-solve barriers to achieving the goals.
Study NCT06193954 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: VasoStar guidewire system
Description: The VasoStar Vibrational Guidewire System vibrates longitudinally at the distal segment of a wire with an electromagnetic source.
Study NCT05878704 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GBT021601
Description: Oral
Study NCT04847596 — intervention group
Intervention type: OTHER
Intervention: Ofatumumab
Description: Prospective observational cohort study. There is no treatment allocation. Patients administered Ofatumumab by prescription that have started before inclusion of the patient into the study will be enrolled.
Study NCT04847596 — intervention group
Intervention type: OTHER
Intervention: Covid-19 vaccine
Description: Prospective observational cohort study. There is no treatment allocation. Participants will obtain the COVID-19 FDA approved Emergency Use mRNA vaccine through their HCP (private insurance) or appropriate federal, state or local program.
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zanzalintinib
Description: Next generation tyrosine kinase inhibitor (TKI) with the target inhibition proﬁle identical to cabozantinib but with a superior pharmacokinetic proﬁle.
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Zanzalintinib
Description: Next generation tyrosine kinase inhibitor (TKI) with the target inhibition proﬁle identical to cabozantinib but with a superior pharmacokinetic proﬁle.
Study NCT06467643 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: non-instrumented root canal treatment with passive ultrasonic activation of heated sodium hypochlorite
Description: Root canals were irrigated with room temperature 5.25% sodium hypochlorite which was activated ultrasonically for 30 seconds and then intra-canal heated using a heat carrier to a temperature fixed at 150 degree celsius. Three consecutive cycles of PAU and intra-canal heating of sodium hypochlorite were performed. After the first and the last cycle, root canals were irrigated with 5 mL of 17% ethylenediaminetetraacetic acid (EDTA) and kept in the canal for 60 seconds and then flushed out with 5 mL of saline. Root canals of this group were kept un-instrumented.
Study NCT06467643 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: conventional root canal treatment with passive ultrasonic activation of heated sodium hypochlorite
Description: Root canals were convetionally prepared using Reciproc Blue rotary files according to the manufacturer's instructions. Once the instrumentation was done, the canal was irrigated with 5 mL of 17% ethylenediaminetetraacetic acid (EDTA) kept for 60 seconds and then flushed with 5 mL of saline. NaOCl was placed in the canal and PUA followed by intracanal heating was performed three times as described for group 1 (IHAN).
Study NCT05329987 — intervention group
Intervention type: OTHER
Intervention: Rehabilitation
Description: Intervention focused on balance, gait and postural transfers rehabilitation. 20 session of 90 minutes (60 minutes of physiotherapy and 30 minutes of occupational therapy), 2 times a week, for 10 weeks.
Study NCT05764356 — intervention group
Intervention type: GENETIC
Intervention: Detection of genotype and RNA profile in platelet and white blood cell
Description: Detection of genotype by next generation sequencing Detection of RNA profile in platelet and white blood cell by RNA sequencing
Study NCT05764356 — intervention group
Intervention type: OTHER
Intervention: Indicators test related to coagulation function
Description: Indicators test including prothrombin time (PT), activated partial thrombin time (APTT), thrombin time (TT), diluted TT (dTT), snake vein enzyme coagulation time (ECT), anti-XA or IIa activity, etc.
Study NCT05764356 — intervention group
Intervention type: OTHER
Intervention: Indicators test related to platelet function
Description: Indicators test related to platelet function. Platelet reactivity was measured by VASP. Platelet aggregation rate was measured by turbidimetric method. Platelet and fibrinolytic function were measured by thrombologram, etc.
Study NCT06382974 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cyst enucleation and bone grafting
Description: cyst enucleation followed by bone grafting the residual bone defects using Atorvastatin combined with β-TCP.
Study NCT01603810 — intervention group
Intervention type: OTHER
Intervention: OCT
Description: Optical coherence tomography of periocular basal cell carcinoma
Study NCT05428046 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Waiting list
Description: Participants assigned to the waiting list group will not receive any intervention until the end of the 12 weeks follow-up. They received the same intervention as the MHL intervention group after the 12 weeks follow-up test.
Study NCT06547099 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical tau PET
Description: Tau PET (flortaucipir)
Study NCT06508619 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Corsano CardioWatch 287-2 non-invasive blood pressure (NIBP) monitoring
Description: Patients receive Corsano CardioWatch 287-2 for continous NIBP monitoring and perform several spot-checks using an automated BP cuff as a reference during the start or uptitration of BP lowering medication
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Durvalumab
Description: Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 (CD279)
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Durvalumab
Description: Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 (CD279)
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tremelimumab
Description: Tremelimumab is a fully human monoclonal antibody used for the treatment of hepatocellular carcinoma designed to attach to and block CTLA-4, a protein that controls the activity of T cells
Study NCT06698250 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tremelimumab
Description: Tremelimumab is a fully human monoclonal antibody used for the treatment of hepatocellular carcinoma designed to attach to and block CTLA-4, a protein that controls the activity of T cells
Study NCT06547099 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Clinical amyloid test
Description: Amyloid PET (florbetapir), CSF amyloid test, or blood amyloid test
Study NCT06547099 — intervention group
Intervention type: OTHER
Intervention: Research blood collection
Description: Research blood assays for amyloid, tau, and neurodegeneration
Study NCT04491578 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACP programme Have a Say
Description: Each dyad of participants will receive a 4-session ACP programme, which consists of educational components, guided reflection, and dyadic ACP discussion, guided by ACP facilitators and an ACP booklet. It is composed of 2 group-based sessions and 2 dyadic discussions. One hour for each session. The group-based sessions are nurse-led, in which dyads of participants will be provided with information about the trajectory of dementia, their future healthcare needs and caring options. Their values and care preferences on future care will be elicited in a consistent manner. The dyadic sessions are led by trained ACP facilitator. Dyads of participants will be supported to have an individualized ACP discussion. By the end of the programme, each dyad of participants will be given an ACP booklet documenting the ACP process.
Study NCT05365152 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Meal Replacement
Description: Meal Replacement
Study NCT05327647 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bicalutamide
Description: Induction intravesical BCG with bicalutamide 150 mg for 90 days
Study NCT05327647 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Control Arm
Description: Induction BCG
Study NCT05632575 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Virtual Promotoras Program
Description: Participants will receive a unique participant code from the virtual promotoras (i.e., patient educators and navigators), to access the VIP mobile phone app intervention. This will give them access to the three main components of the VIP intervention:~1. Educational Modules (8 evidence-based educational modules made by the VPs),~2. Sexual and Reproductive Health Plan (SRHP): Quiz-style instrument to help the participant set goals for her sexual health and develop a set of questions to ask her provider.~3. Virtual Promotora's (VP) chat room.: Opportunity for participant to ask any questions that she may have about sexual health (SH) or sexual healthcare access (SHCA), refine her SRHP. The VP will also help her make her appointment for her clinical visit with one of the local free clinics which do not require insurance and are youth-friendly, and practice having the conversation that she wants to have with her clinical provider.
Study NCT06564558 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Spinal Strengthening Exercises
Description: Individuals in the experimental group will carry out 3 sets of 10 repetitions or what is tolerated within a Borg scale intensity of 4-5 with 70-80% of perceived exertion with appropriately picked elastic bands. The exercises include: Shoulder horizontal abduction; Shoulder elevation; Back Extensions over a plinth; Shoulder extension exercises; One arm and opposite leg lifts from quadruped; and finally bilateral arm lifts with upper thoracic extension from prone (superman exercise).
Study NCT06564558 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thoracic Spine Stretching
Description: Participants will be instructed to do two exercises: Firstly, to lay supine with and hinge the thoracic spine over a roller placed in a way that would ensure the patient is forward lying and not completely supine. The participant will be instructed to maintain hinging until a stretch or pressure feeling is felt in the midback and hold this position for 3 sets of 30 seconds. Secondly, the patient was asked to be in a seated position, clasp the hands together and behind the head while arching backward over the chair and looking up. This exercise will be done for 3 sets of 20-30 repetitions with a slight hold time at the end of the movement. All interventions will be carried out for 45 minute sessions 3 times per week.
Study NCT06564558 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Thoracic Spine Mobilization
Description: The patient will be seated with both hands clasped at shoulder level. An experienced and blinded therapist standing homolateral to the patient supports the clasped hands with one arm while placing the other hand was placed at different thoracic regions until the thoracolumbar junction. Specifically, the dorsal aspect of the index finger and pad of the thumb were used to create a fixation point at the junction. Following that, gentle extension-directed glides (postero-anterior) will be done by the therapist for 3 sets of 10 repetitions or until tolerated by the patient.
Study NCT06564558 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham Postural Correction
Description: comprised an hour of social interaction with similar participants where a blinded therapist will provide educational tips for dealing with kyphosis along with educational reading material for each participant.