AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05854758 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional treatment
Description: A detailed musculoskeletal examination of lumbar spine will be performed before the start of treatment. Oswestry Low Back Pain Disability Questionnaire for pain will be noted. An expert physical therapist with more than 7 years clinical experience will assist the patients in performing core stabilization exercise with conventional physical therapy protocol and routine physical therapy exercise. The session with the physical therapist will usually last for up to 40 minutes.~This group will perform knee to chest, pelvic rotation, bridge and back extension exercises after baseline treatment of therapeutic hot pack and transcutaneous electrical nerve stimulation. continuous mode for 10 minutes. Each exercise will be repeated 10 times, with 10 second holds, followed by a five-minute rest interval
Study NCT05197166 — intervention group
Intervention type: OTHER
Intervention: Acute Clinical Settings
Description: Acute clinical settings, like hospitals, where students are exposed to normal daily shift activities, involving prolonged walking and standing positions.
Study NCT04609306 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: H2O2 application to incision
Description: A lap sponge soaked in 3% H2O2 will be applied to the incision and allowed to sit for 3 minutes.
Study NCT06063018 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48 + Tislelizumab
Description: RC48: intravenous drip, 2mg/kg, D1, repeated once every 2 weeks. Tislelizumab: intravenous drip, fixed dose 600 mg, D1, repeated once every 6 weeks.
Study NCT05451836 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Patient education leaflets
Description: Patients who attend the emergency department with upper respiratory tract infections will be provided with patient education leaflets on appropriate antibiotic use and antimicrobial resistance. The leaflets are available in the four national languages in Singapore.
Study NCT05451836 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physician feedback
Description: All physicians working in the emergency department will receive a text message from their department head on their antibiotic prescribing rates every two months.
Study NCT05528016 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Upper Eyelid Blepharoplasty
Description: Blepharoplasty is a procedure that the skin, orbicularis oculi muscle, and fat pads are excised to treat visual field loss caused by dermatochalasis.
Study NCT04661800 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Sniffin's stick test
Description: The sniffin's stick test is a three-part test consisting of smelling odor pens: 1) determining a detection threshold, 2) discriminating ability, 3) ability to identify odors. It lasts about 30 minutes, is achievable in the room.
Study NCT05223127 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Aloe vera
Description: The leaves of Aloe vera (Aloe barbadensis) will be identified and verified by Selçuk University Faculty of Agriculture. Aloe vera leaves will be washed with antiseptic solution and cut crosswise using gloves and sterile knife. The thick epidermis will be removed from the middle of the leaf. The gel will be obtained from the parenchyma of the thick juicy leaves of aloe vera.
Study NCT05157373 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Endometrial sampling and Peripheral blood collection
Description: The endometrial biopsy will be performed with a pipette. The pipelle will be inserted gently through the cervix and into the uterus. The pipelle procedure takes approximately one minute and involves gently moving the pipelle back and forth to obtain a sample. Then 10cc of peripheral blood will be collected.
Study NCT05157373 — intervention group
Intervention type: BEHAVIORAL
Intervention: FSFI Scale
Description: The participants will fill up the Female Sexual Function Index (FSFI) questionnaire.~The FSFI is a 19-item self-report questionnaire designed to measure sexual functioning in women. It assesses six domains of sexual function: sexual desire, sexual arousal, lubrication, orgasm, satisfaction, and pain (i.e., pain associated with vaginal penetration).
Study NCT05993104 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Intrachamber ultrasound
Description: Ultrasound left atrial geometry collecting using AcQMap.
Study NCT05993104 — intervention group
Intervention type: OTHER
Intervention: Statistical shape analysis
Description: Statistical shape analysis tools used to investigate left atrial geometry
Study NCT06037980 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: ◦ Gemcitabine 800 mg/mq iv, day 1 and 8 of 21-day cycles, for 3 cycles
Study NCT06037980 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nab paclitaxel
Description: ◦ Nab-paclitaxel 100 mg/mq, day 1 and 8 of 21-day cycles, for 3 cycles
Study NCT06037980 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: ◦ Cisplatin 25 mg/mq iv, day 1 and 8 of 21-day cycles, for 3 cycles
Study NCT06037980 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Curative Surgery
Description: Curative surgery on primary tumor
Study NCT06037980 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Curative Surgery
Description: Curative surgery on primary tumor
Study NCT06037980 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: 1250 mg/m2 given orally twice daily on days 1 to 14 of a 3 weekly cycle for a total of 8 cycles
Study NCT06037980 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Capecitabine
Description: 1250 mg/m2 given orally twice daily on days 1 to 14 of a 3 weekly cycle for a total of 8 cycles
Study NCT05534438 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Stereotactic body radiotherapy
Description: SBRT will be initiated as soon as possible, at not beyond 8 weeks of baseline measurements. Recommended dosing is per department standards for oligometastatic disease (ie, 10 Gy x 3 or 7-8 Gy x 5 fractions daily, excluding weekends and departmental holidays)
Study NCT05313308 — intervention group
Intervention type: DRUG
Intervention: Midazolam
Description: Midazolam oromucosal solution
Study NCT06294470 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Ballon expulsion test
Description: Rectal latex balloon probe filled with saline solution. Patients expelled balloon and time recorded (\<1 or >1 min).
Study NCT06294470 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ballon expulsion test
Description: Rectal latex balloon probe filled with saline solution. Patients expelled balloon and time recorded (\<1 or >1 min).
Study NCT06294470 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Colonic transit time
Description: Patients ingested capsules with 24 radiopaque markers and underwent standing abdominal radiographs on Day 3 and Day 5. Over 80% expulsion within five days was considered normal, while retention indicated defecatory obstruction.
Study NCT06294470 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Colonic transit time
Description: Patients ingested capsules with 24 radiopaque markers and underwent standing abdominal radiographs on Day 3 and Day 5. Over 80% expulsion within five days was considered normal, while retention indicated defecatory obstruction.
Study NCT06294470 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Stapled hemorrhodopexy
Description: Circumferential stapled hemorrhoidopexy with a 34mm circular stapler is a surgical procedure used to treat mucohemorrhoidal prolapse.
Study NCT06294470 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Stapled hemorrhodopexy
Description: Circumferential stapled hemorrhoidopexy with a 34mm circular stapler is a surgical procedure used to treat mucohemorrhoidal prolapse.
Study NCT05712772 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blue Light
Description: Blue light exposure
Study NCT05712772 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Red Light
Description: Red light exposure
Study NCT04976725 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Osteopathic Manipulative Therapy
Description: 75 individuals will be included in our study, including 3 groups: control group (N= 25), osteopathic manipulative technique (n= 25), myofascial relaxation group (n=25). Which group of individuals will be determined by randomizing them with closed envelope method.~Osteopathic Manipulative Therapy and myofascial relaxation treatment applications will be applied 2 days a week, for periods of 30 min for 4 weeks.
Study NCT04559230 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sacituzumab Govitecan
Description: Sacituzumab Govitecan will be administered by IV infusion over 3 hours for first administration and over 1 hour if tolerated. Subjects will be allowed to continue treatment until they have evidence of significant treatment-related toxicity or progressive disease.
Study NCT04820218 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: With Try-on glasses
Description: Subjects will be asked to measure their visual acuity with their try-on glasses
Study NCT05352243 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Expressive Disclosure
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their writing will remain confidential. Three writing sessions will be spaced 1-2 weeks apart. A weekly writing prompt will instruct participants to write about their deepest thoughts and feelings surrounding their bereavement experience.
Study NCT05352243 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Expressive Helping
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their first two writing will remain confidential, and their final essay will be de-identified before being provided to newly bereaved young adults. Three writing sessions will be spaced 1-2 weeks apart. In the first two writing sessions, participants will receive a writing prompt that will instruct them to write about their deepest thoughts and feelings surrounding their bereavement experience. For the final writing session, participants will receive a writing prompt instructing them to provide advice and support for a newly bereaved young adult.
Study NCT05352243 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: Fact-Writing
Description: Prior to each writing session, participants will receive general instructions for completing the writing (e.g., write continuously for 20 minutes, do not worry about grammar, sentence structure, repetition), and be reminded that their writing will remain confidential. Three writing sessions will be spaced 1-2 weeks apart. A weekly writing prompt will instruct participants to write objectively about different time frames (e.g., routine for getting up in the morning, routine for going to sleep at night).
Study NCT06380569 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: KF-STRIDE®
Description: Treatment group will receive 10 web based sessions of a strength-based training tool (once or twice a week). Sessions are approximately 60 minutes long.
Study NCT05724992 — intervention group
Intervention type: GENETIC
Group type: OTHER
Intervention: Saliva swab testing
Description: 41 pancreatic cancer predisposition genes will be tested through a saliva-based swab
Study NCT05623527 — intervention group
Intervention type: DEVICE
Intervention: cardiac electronic implants
Description: Cardiac electronic implants(CIED) includes permanent pacemaker (PPM), implantable cardioverter defibrillator (ICD), three-chamber pacemaker for cardiac resynchronization therapy defibrillator, lead free pacemaker, etc.
Study NCT05110027 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enpatoran
Description: Participants will receive single oral dose of enpatoran tablet on Day 1
Study NCT05110027 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]enpatoran microtracer
Description: Participants will receive single oral dose of non-labeled enpatoran solution spiked with microtracer of \[14C\]enpatoran on Day 1 of Period 1.
Study NCT05110027 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]enpatoran microdose
Description: Participants will receive intravenous \[14C\]enpatoran microdose administered at 1.5 hours after the oral dose of enpatoran on Day 1 of Period 2.
Study NCT05076084 — intervention group
Intervention type: PROCEDURE
Intervention: QUICK questionnaire and 6 additional questions
Description: QUICK questionnaire and 6 additional questions
Study NCT05076084 — intervention group
Intervention type: OTHER
Intervention: Retrospective collection of clinical data from the patients' medical records
Description: Retrospective collection of clinical data from the patients' medical records
Study NCT05565027 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dynamic digital radiography
Description: The use of advanced dynamic X-ray photography and acquisition technology can obtain high-definition dynamic lung images of patients throughout the respiratory cycle for analysis.
Study NCT05565027 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pneumotachograph
Description: The pneumotachograph monitors the flow rate, and the lung volume is calculated by integrating.
Study NCT05489042 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Repetitive Transcranial Magnetic Stimulation (rTMS)
Description: 5 Sessions of rTMS - brief single pulse TMS or short TMS pulse bursts consisting of 2-5 pulses delivered per second at a standard intensity. If a brief single pulse TMS is applied, a standard single pulse TMS procedure will be used - This procedure consists of 10 trains of 180 seconds duration and each train will be separated by at least 30 seconds. If short TMS pulse bursts are applied, a standard theta-burst TMS procedure will be used - This procedure consists of TMS triplets (i.e., 3 pulses) that repeat for 10 trains of a total duration of 40-190 seconds and these bursts will be separated by at least 6 seconds and each train will be separated by at least 30 seconds
Study NCT05489042 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham rTMS
Description: 5 sessions of sham rTMS
Study NCT05901974 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Venetoclax
Description: Venetoclax orally once daily (100 mg d1, 200 mg d2, 400 mg d3-28);
Study NCT05901974 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: azactidine
Description: azacitidine 75 mg/m2 subcutaneously once daily on days 1-7
Study NCT04616534 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biopsy
Description: Undergo biopsy (dose expansion cohort only)
Study NCT04616534 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biospecimen Collection
Description: Undergo collection of blood samples
Study NCT04616534 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic Imaging
Description: Undergo medical imaging scans
Study NCT04616534 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Elimusertib
Description: Given PO
Study NCT04616534 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gemcitabine
Description: Given IV
Study NCT05203185 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pulmonary Embolism Risk Kalculator (PERK)
Description: Nudges are applications of behavioral science, defined as positive reinforcement and indirect suggestions that have a non-forced effect on decision making. Nudges will be to the PE CALC CDS tool to develop the new CDS tool, PERK.
Study NCT05869474 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Iodine125-Seeds implantation
Description: Endoscopic ultrasound-guided intratumoral iodine125-Seeds implantation
Study NCT05869474 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gem/nab-P Chemotherapy
Description: nab-paclitaxel (125 mg per square meter of body-surface area) followed by gemcitabine (1000 mg per square meter) on days 1, 8 every 3 weeks
Study NCT05869474 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gem/nab-P Chemotherapy
Description: nab-paclitaxel (125 mg per square meter of body-surface area) followed by gemcitabine (1000 mg per square meter) on days 1, 8 every 3 weeks
Study NCT05172570 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Gabapentin
Description: Gabapentin is a common medication used preoperatively and postoperatively as part of multimodal analgesia to help with acute pain.
Study NCT05147844 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Toripalimab
Description: Toripalimab: 240mg, iv. Q3W for 1 year or until disease progression/intolerable toxicity~Radiotherapy:~Newly diagnosed patients: IMRT for nasopharynx lesions and cervical lymph nodes, pGTVnx 70 Gy, pGTVnd 99Gy, pCTV1, 60 Gy, pCTV2, 54 Gy, 33 times, completed in 7 weeks.~Relapsed patients: IMRT for nasopharynx lesions and cervical lymph nodes, pGTVnx 60Gy, pGTVnd 60Gy, 20-25 times, completed in 4-5 weeks.~Newly diagnosed and relapsed patients: SBRT for oligometastatic lesions, pGTV 25-40 Gy, 3-5 times, completed in 1-2 weeks.
Study NCT04948047 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pathological examinations as the golden diagnosis criteria
Description: Pathological diagnosis, as the golden standard for diagnosing pulmonary nodules, is achieved by two experienced pathologists and validated by the third senior pathologist.
Study NCT05108129 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: M-TAPA block
Description: After tracheal intubation, a high-frequency linear probe will be placed in the sagittal direction at the 10th costal margin, and transversus abdominis, internal oblique, and external oblique muscles will be identified. A block needle will be inserted with in-plane technique and 25 ml 0.25% bupivacaine will be injected between the transversus abdominis muscle and the lower aspect of the costal cartilage. The same procedure will be repeated on the contralateral side.~Standard perioperative and postoperative multimodal analgesia The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). Patients will receive standard multimodal analgesia comprising paracetamol, dexketoprofen, and tramadol.
Study NCT05108129 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: OSTAP block
Description: The patients will receive oblique subcostal TAP block in the supine position immediately after the endotracheal intubation. The anesthesiologist of the operating room will place the ultrasound with a linear probe subcostally and from the xiphoid to the right iliac crest obliquely. Rectus abdominis muscle and underlying transversus abdominis muscle, will be identified near the costal margin. The needle will be directed to the transversus abdominis fascia. Local anesthetic solution of 25 ml 0.25% will be injected to between rectus abdominis and transversus abdominis muscles along the oblique subcostal line. The same procedure will repeated to the contralateral side.~Standard perioperative and postoperative multimodal analgesia The pain intensity during rest and motion will be evaluated with the 0-10 Numeric Rating Scale (NRS). Patients will receive standard multimodal analgesia comprising paracetamol, dexketoprofen, and tramadol.
Study NCT04472559 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Self-acupressure
Description: Self-acupressure
Study NCT06473805 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: VISTA technique and 3D printed PMMA implant
Description: Intraoral scanning and radiographic examination (CBCT) will be performed to assess the anatomy of the sub nasal area and plan the position, size and thickness of PMMA implant The data will be transferred to 3D planning software to create digital model that fit in the defect followed by 3D printing of the implant using VISTA technique
Study NCT06473805 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: VISTA technique and 3D printed PEEK implant
Description: Intraoral scanning and radiographic examination (CBCT) will be performed to assess the anatomy of the subnasal area and plan the position, size and thickness of PEEK implant The data will be transferred to 3D planning software to create digital model that fit in the defect followed by 3D printing of the implant using VISTA technique
Study NCT04948047 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Breath test combined with computed tomography
Description: Exhaled breath of each participant will be collected with Tedlar bags. The volatile organic compounds will be detected by a high-resolution high-pressure photon ionization time-of-ﬂight mass spectrometry (HPPI-TOFMS).~The Imaging markers of pulmonary nodules, including the size, three-dimensional shape, and appearance characteristics, are derived from the chest computed tomography within 2 weeks before surgery resection.
Study NCT05502913 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antibiotics
Description: Recipients will undergo bowel preconditioning with antibiotics (Rifaximin) following randomization.
Study NCT05502913 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: FMT (Fecal Microbiota Transplantation)
Description: FMT involves the transplantation of fecal bacteria from a screened donor to a recipient. This will be achieved per os in the form of a capsule containing freeze-dried stool obtained from the donor.