AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04761302 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Use of non-steroid anti-inflammatory drugs (NSAIDS) as an alternative for post-operative pain management after a femur and tibia fracture
Description: This is a randomized controlled, single blind, parallel groups, opioid control trial of all patients (total of 150 patients) who suffered tibial and femoral shaft fractures and were treated with intramedullary nailing. Patients will be aleatory assigned to two study groups: Group-1 will receive non-opioid medications, and Group-2 will receive opioid medications. During the inpatient postoperative period, patients will undergo subjective evaluation of pain utilizing a previously validated questionnaire, the Visual Analogue Score (VAS). The first questionnaire will be completed twelve hours after surgery and during subsequent twelve-hour intervals until discharge. Secondary outcomes will include efficiency such as time to gastrointestinal motility, time to weight bearing of affected limb, resumption of ambulation, and length of hospital stay. The evaluation will take approximately 15 minutes to complete each time, we the entire participation time to be 60 minutes.
Study NCT06475443 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pyrotinib plus capecitabine
Description: oral
Study NCT05873426 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] ZSP1273
Description: 600 mg suspension containing 50μCi of \[14C\]ZSP1273
Study NCT05206019 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albuvirtide
Description: Long-Acting HIV-1 Fusion Inhibitor (chemically modified peptide targeting HIV-1 gp41)
Study NCT01452698 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Placebo
Description: TAK-438 placebo-matching tablets, orally, once daily for up to 8 weeks.
Study NCT05399043 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Multidisciplinary Conventional Neuromotor Rehabilitation
Description: Patients will receive conventional treatment consisting of two daily one-hour session (4 weeks) and including traditional rehabilitation activities like range of motion exercises (passive, active assisted and active), progressive resistive exercises, balance and strength training, and aerobic conditioning. The intervention procedures will follow the routine multidisciplinary clinical practice of the Institute where the study will be carried out. Procedures will be adapted according to patient's medical diagnosis, disability severity, and to the consequent rehabilitation objectives in favor of an individualized rehabilitation project and program. If necessary, patients might therefore undergo parallel rehabilitation activities (ie, occupational therapy, speech therapy, cognitive stimulation) that will be kept under control throughout data collection and analyses.
Study NCT05399043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multidisciplinary Conventional Neuromotor Rehabilitation
Description: Patients will receive conventional treatment consisting of two daily one-hour session (4 weeks) and including traditional rehabilitation activities like range of motion exercises (passive, active assisted and active), progressive resistive exercises, balance and strength training, and aerobic conditioning. The intervention procedures will follow the routine multidisciplinary clinical practice of the Institute where the study will be carried out. Procedures will be adapted according to patient's medical diagnosis, disability severity, and to the consequent rehabilitation objectives in favor of an individualized rehabilitation project and program. If necessary, patients might therefore undergo parallel rehabilitation activities (ie, occupational therapy, speech therapy, cognitive stimulation) that will be kept under control throughout data collection and analyses.
Study NCT05399043 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Technology-based Rehabilitation
Description: According to their individualized rehabilitation project, patients will undergo RAT or non-immersive VR-based rehabilitation.~RAT will consist of three times a week one-hour session (4 weeks) and will be conducted by the implementation of an exoskeleton device for the upper limbs (Armeo-Spring™) or for the lower limbs (Lokomat™).~VR-based rehabilitation will consist of one daily one-hour session (4 weeks) and will be conducted by the implementation of a single non-immersive VR device among the Riablo™ (Corehab, Italy), the ProKin 252™ (TechnoBody SRL, Italy), the D-Wall™ (TechnoBody SRL, Italy), the Walker View™ (TechnoBody SRL, Italy).~Part of the duration of the whole treatment will be dedicated to the use of the device, resulting in the same amount of rehabilitation for all participants.
Study NCT06256406 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: in the field of rehabilitation and neonatal care: the combination of Kangaroo care method and music therapy
Description: Kangaroo care is a practice involving skin-to-skin contact between the infant and a caregiver,. Music therapy is a therapeutic approach that utilizes the expressive and emotional qualities of music to address physical, emotional, cognitive needs of individuals.
Study NCT04862871 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Physical Activity - Pediatric Pain Rehabilitation Center
Description: While admitted to the Pediatric Pain Rehabilitation Center program, patients receive 1-3 hours of individual and group physical therapy 5 times per week and completed a 30-60 minute home exercise program 9 times per week. The median length of stay for the program is 5 weeks. The amount of aerobic exercise prescribed is individualized to each patient and ranged from 10-20 minutes per session. The duration of aerobic exercise prescribed progressed by 5-10 min weekly until the child reached 20-30 minutes. Patients are instructed to reach a moderate to vigorous intensity of exercise (defined at 5-7/10 rate of perceived exertion). The mode of exercise varied dependent on patient ability and interest. Typical modes of exercise included: walking, running, stationary biking, swimming, sports (i.e., soccer, dance), and online aerobic workouts. Patients were prescribed an individualized 30-60 minute discharge home program using the same structure upon completing the program.
Study NCT06110325 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cawthorne and Cooksey exercise program
Description: Participants in this group will receive an exercise program based on Cawthorne and Cooksey exercises. The intervention will last for 4 weeks, taking place three times a week, with the first session conducted in person and the remaining two assisted via video from their homes.
Study NCT06110325 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control
Description: Control group will receive counseling focused on fall prevention and promotion of an active, healthy lifestyle through informational leaflets.
Study NCT05615090 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Arm I (Prepectoral),
Description: The intervention will be delivered through a smartphone app. The app provides users with ED symptom self-monitoring, psycho-education and relapse prevention in an evidence-based CBT-E.
Study NCT05615090 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Arm II (Subpectoral)
Description: The intervention will be delivered through a smartphone app. The app provides users with ED symptom self-monitoring, psycho-education and relapse prevention in an evidence-based CBT-E.
Study NCT05504863 — intervention group
Intervention type: DRUG
Intervention: Ferric carboxymaltose
Description: As part of the RAPIDIRON Trial, maternal participants randomized to intervention arm 1 were given a single dose of ferric carboxymaltose between 14 and 17 weeks of pregnancy.
Study NCT05504863 — intervention group
Intervention type: DRUG
Intervention: Iron isomaltoside
Description: As part of the RAPIDIRON Trial, maternal participants randomized to intervention arm 2 were given a single dose of iron isomaltoside between 14 and 17 weeks of pregnancy.
Study NCT05504863 — intervention group
Intervention type: DRUG
Intervention: Ferric Sulfate
Description: As part of the RAPIDIRON Trial, maternal participants randomized to the active comparator arm were given 200 ferrous sulfate tablets immediately after randomization (\~12 weeks of pregnancy). Participants were instructed to take two tablets a day, with each tablet containing 60mg elemental iron.
Study NCT06115551 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Fasting Mimicking Diet
Description: FMD is a 5-day low calorie fasting-mimicking diet.
Study NCT01114061 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Insupatch
Description: Applying heat to the infusion site using the insupatch device
Study NCT05446688 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 6MW3211
Description: 6MW3211 injection, 45mg/kg, Q2W
Study NCT05975203 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: skin-to-skin contact
Description: Immediately after delivery the infant will receive skin-to-skin contact with the mother.
Study NCT04662489 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Pulmonary vein electrical isolation
Description: Electrical isolation of the pulmonary veins from the left atrium with cryoablation therapy
Study NCT04662489 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radial ablation
Description: Electrical isolation of the pulmonary veins from the left atrium plus radial ablation of rotational activity sites with radiofrequency ablation.
Study NCT05397951 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Multi-modality Noninvasive Biosensor
Description: The wearable sensor devices will be placed on the finger, wrist, temple, subclavian, arm, neck, and thigh of the participant and will provide continuous tissue mechanics, heart rate, respiration rate, blood flow, and pulse oxygenation measurements continuously throughout the experimental period.
Study NCT05397951 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Oximeter
Description: The oximeter device will be placed on the right middle finger of the participant and will provide continuous pulse oxygenation and heart rate measurements continuously throughout the experimental period.
Study NCT05158582 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SPECIFIC MODIFIED EXERCISE PROGRAM GROUP
Description: The modified exercise program group will perform following exercises:~Resisted static Squats SLER Banded rows SL Banded Jumps Resisted explosive reverse lunges 5hurdle Jumps Elevated single leg Swiss ball Bosu Banded Stars RLE Barbell lunge Static shoulder Abd.with banded leg Add Ant.Banded static squat with medball press Bosu banded superman Sit ups
Study NCT05158582 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CONVENTIONAL EXERCISES PROGRAM GROUP
Description: The conventional exercise program group will perform the same exercises as they doing for their low back pain.
Study NCT06323577 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Restricted kinematic alignment
Description: TKA using restricted kinematic alignment under robotic assisted surgery (MAKO).
Study NCT06323577 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical alignment
Description: TKA using mechanical alignment under robotic assisted surgery (MAKO).
Study NCT04984525 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYNB1934
Description: SYNB1934 is formulated as a nonsterile solution intended for oral administration
Study NCT04984525 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SYNB1618
Description: SYNB1618 is formulated as a nonsterile solution intended for oral administration
Study NCT04664439 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: CT-FFR
Description: CCTA examination will be performed by qualified medical imaging technicians, and patients will be scanned with 256rows of CT, according to standard operating norms. The coronary artery physiological function evaluation software(Keya Medical Technology, Beijing, China)will be configured in the core laboratory in advance, and the relevant imaging analysts will be trained. The core laboratory will receive the CCTA inspection data and evaluate the CCTA image quality. According to the standard operation flow of the software specification, the CT-FFR analysis will be carried out on the images that meet the requirements, and the CT-FFR value of the lesions will be measured.
Study NCT05397951 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Portable Blood Pressure Monitor
Description: The blood pressure monitor device will be placed on the left arm of the participant and will take a blood pressure measurement every 5 minutes throughout the 15 minute experimental period, and every 15 minutes throughout the 2 hour experimental period.
Study NCT06088212 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Disease management program
Description: The components of our DMP include:~1. Intensive post-discharge education~2. Home surveillance of signs and symptoms will be reviewed (weekly in the first month and monthly thereafter) in a telehealth consultation with patient and/or carer.~3. Medical treatment involves a planned up-titration of cardioprotective medications that will proceed in the absence of advice from the general practitioner (GP) to the contrary. Close observation and frequent appointments are organised by the nurse with the patient's GP during up-titration period.~4. Exercise program delivered by an exercise physiologist~5. Maintenance phase of the DMP: During this maintenance phase, Intervention patients should have been fully transitioned to home care where they are managed by their GP at optimal doses of their medications. Repeated education and exercise guidance will continue with the carer, supported by our cardiac nurse and exercise physiologist via telehealth consultation bimonthly.
Study NCT05397951 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Vicorder Pulse Wave Velocity Monitor
Description: The pulse wave velocity monitor device will be placed on the right side of the neck and the right thigh and will provide measurements continuously throughout the experimental period.
Study NCT03206814 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Antihypertensive therapy is adjusted every 3 months on the basis of office blood pressure values.
Study NCT03206814 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: POST-strategy
Description: Antihypertensive therapy is adjusted every 15 days on the basis of home blood pressure values.
Study NCT05135767 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Brief Motivational Interviewing with Personalized Feedback
Description: A brief motivational interviewing (MI) intervention will target drinking. The intervention will leverage in-depth personalized feedback to identify areas of progress and barriers to change. The personalized feedback will include results of laboratory diagnostic tests, summary reports of timeline followback interviews, and graphical depictions of self-monitoring reports collected on smartphones in daily life. The brief intervention will include an initial 60-minute videoconference session, two brief, 5-10 minute phone-call check-ins completed one and two weeks after the initial intervention, and a 30-minute videoconference booster session completed three weeks after the initial intervention.
Study NCT04845568 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Experience
Description: The virtual reality experience includes psychoeducation content about healthy eating and consideration of future consequences. It includes a game where participants are in a go kart and pick up healthy or unhealthy foods on the road. Participants play in the present and in the future.
Study NCT06269432 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Precision Antiplatelet Therapy Trial Group
Description: Use SPCM method to detect platelet aggregation function in patients, adjust antiplatelet drugs based on the test results, and receive precise antiplatelet treatment for 12 months. Non resistant patients with aspirin will continue to receive aspirin 100mg qd; Patients with aspirin resistance were given clopidogrel 75mg qd; Clopidogrel resistant patients were given ticagrelor 90mg bid.
Study NCT06269432 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Traditional Antiplatelet Therapy Control Group
Description: No adjustment of antiplatelet medication is required, and routine treatment with aspirin 100mg qd is given for 12 months.
Study NCT05030987 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Renal Denervation
Description: Renal denervation in patients with HFpEF and uncontrolled hypertension
Study NCT05030987 — intervention group
Intervention type: PROCEDURE
Group type: SHAM_COMPARATOR
Intervention: Sham
Description: Sham Treatment. After six months, cross-over is planned in all sham-treated patients and this patients will also receive a renal denervation.
Study NCT05760339 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time-restricted feeding
Description: Subjects in the will be instructed to follow a TRF regimen consisting of a daily 8h ad libitum eating period and 16h water fasting period during the last 2 weeks before surgery. Participants will be encouraged to begin their eating period at 08:00h and end it at 16:00h, since the metabolic benefits of TRF appear to be considerably more pronounced when the eating period starts early in the day.
Study NCT05760339 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Carbohydrate loading
Description: Subjects will continue their usual diet and will receive two quantities of a clear beverage containing 12.5 g/100 mL maltodextrin (50 kCal/100 mL, pH 5.0); 800 mL at 22.00h on the evening before surgery and 400 mL two hours before anaesthesia induction.
Study NCT04924543 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Online self-learning training module
Description: Training module in optical diagnosis of IBD-associated dysplastic lesions during gastrointestinal endoscopy
Study NCT04924543 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Refresher training
Description: Brief refresher training in optical diagnosis of IBD-associated dysplastic lesions during gastrointestinal endoscopy
Study NCT06336954 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Adibelimab
Description: Adibelimab (1200mg, IV, every 3 weeks) combined with Famitinib (20mg, daily, orally) and Albumin-bound Paclitaxel (260mg/m2, Day 1, every 3 weeks)
Study NCT06340399 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: BCAA
Description: patients administering BCAA
Study NCT06340399 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: patient not administered BCAA
Description: patients not administered BCAA
Study NCT04833699 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: rubber water bag
Description: bboiled tap water (80 °C) was put in a rubber water bag with a fluffy cover (Fig. 1), and placed on the patient's abdomen at 3, 6, 9, and 12 h after the surgical procedure for 30 minutes in addition to clinical standard postoperative care (ERAS protocol)
Study NCT05720988 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azacitidine
Description: Given SC
Study NCT05720988 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Tagraxofusp-erzs
Description: Given IV
Study NCT05720988 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Tagraxofusp-erzs
Description: Given IV
Study NCT06222385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Device measurements during overnight sleep and morning wake
Description: Overnight period and morning period device measurements
Study NCT06222385 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Device measurements during overnight wake and morning sleep
Description: Overnight period and morning period device measurements
Study NCT06033014 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PM HeartIHD prediction
Description: The calculated prediction and the explainability factors will be made available to the physician, which the physician then can decide to take into his/hers evaluation about further treatment.
Study NCT04869943 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Enobosarm
Description: Oral Enobosarm 9mg per day
Study NCT04869943 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Exemestane
Description: Exemestane monotherapy, exemestane plus everolimus, or selective estrogen receptor modulator (SERM)
Study NCT04896112 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: LNK01002
Description: LNK01002 will be administrated orally.
Study NCT04507126 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bacillus Calmette-Guerin (BCG)
Description: Vaccine
Study NCT04977141 — intervention group
Intervention type: OTHER
Intervention: Decisional Conflict Scale
Description: Decisional Conflict Scale
Study NCT05835284 — intervention group
Intervention type: DEVICE
Intervention: Investigational Edge-on Silicon Photon Counting CT device
Description: Administration of IV contrast material, if applicable, shall be done according to the hospital's SOC. Administration of oral contrast material, if applicable, shall also be done according to the hospital's SOC. Images will then be compared with the previously acquired CT conducted as standard of care. The investigational scan will take approximately 60-120 minutes.
Study NCT04969978 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Academic Detailing
Description: * Group training of clinic staff prior to activation of the eReferral system and 12 months post-activation~* Follow-up booster sessions~* Monthly performance audit and feedback
Study NCT04969978 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Informational Intervention
Description: Receive overview of Quitline services and use of Quitline eReferral via online materials
Study NCT04969978 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Informational Intervention
Description: Receive overview of Quitline services and use of Quitline eReferral via online materials