AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05460559 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Group B (s-ECIRS) procedure
Description: The patients will be in Galdakao-Modified Supine Valdivia (GMSV) position . Under fluoroscopic guidance, the desired calyces will be punctured using an 18 G coaxial needle. Then 0.038 mm hydrophilic guidewires will be passed percutaneously through the needle into the pelvis. Using metal dilators dilatation will be carried out till 30 Fr. Amplatz sheath will be inserted to allow a 26 Fr nephroscope to enter the collecting system. Retrograde intrarenal surgery will be applied simultaneously by a second surgeon using flexible ureteroscopy. The stones will be fragmented with holmium-yttrium-aluminum-garnet (YAG) laser and stone fragments will be evacuated by basket or removed through PCNL tract under nephroscopy.
Study NCT05417360 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Akkermansia muciniphila
Description: During the weight management period (weeks 8 to 32), the pasteurized A. muciniphila product will be orally consumed in water at least 15 min before breakfast for a period of 6 months (24 weeks) capsules. It appears as a white homogenous powder.~.
Study NCT05417360 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: During the weight management period (weeks 8 to 32), the placebo product will be orally consumed in water at least 15 min before breakfast for a period of 6 months (24 weeks). It appears as a white homogenous powder.
Study NCT06375252 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Central Jugular Vein Catheter Lumen Holder Apparatus
Description: Participants will experience the central jugular vein catheter lumen holder apparatus, perform walking, sitting, supine, right and left side lying activities and fill out the evaluation forms prepared by the researcher. They will then experience the same activities without the apparatus.
Study NCT04641819 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Yangzheng Compound Mixture
Description: At the end of the treatment period, the investigator can decide whether to continue the medication based on the improvement of the subjects' sleep disturbance.~Medication during the follow-up period: subjects will enter the follow-up period after completing one course of Yangzheng Compound Mixture treatment or the end of the treatment period. Visits will be conducted once every 3 weeks, at least 2 times and no more than 4 times. For subjects in the experimental group, doctors can decide whether the patients should continue to receive Yangzheng Compound Mixture therapy in the follow-up period according to the improvement of sleep disorders, while for subjects in the control group, the patients can choose to start receiving Yangzheng Compound Mixture therapy in the follow-up period according to their own wishes and doctors' suggestions.
Study NCT04641819 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Conventional Treatment
Description: Including treatment of sleep disorders and tumor which shall follow the clinical guidelines.
Study NCT04641819 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Conventional Treatment
Description: Including treatment of sleep disorders and tumor which shall follow the clinical guidelines.
Study NCT05833217 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Adipose Tissue Biopsy
Description: After an overnight fast, approximately 1-2 grams of subcutaneous fat will be removed by a needle. Participants will have a local anesthetic prior to the procedure. The needle fat biopsy will be repeated at quarterly intervals for one year (every 3 months). We will also draw 1 10mL tube of blood at each biopsy for measurement of inflammatory cytokines.
Study NCT04871542 — intervention group
Intervention type: PROCEDURE
Intervention: Biospecimen Collection
Description: Undergo collection of blood sample
Study NCT04871542 — intervention group
Intervention type: OTHER
Intervention: Questionnaire Administration
Description: Complete questionnaires
Study NCT05833217 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Steady State Plasma Glucose (SSPG) Test
Description: An Insulin Sensitivity Test (SSPG: Steady State Plasma Glucose) is performed to determine if participants are insulin sensitive or insulin resistant. This test is approximately 5-6 hours in length. Participants will be asked to fast for 12 hours. The insulin sensitivity test is designed to measure how well your cells remove glucose from your blood in response to insulin. During this test participants will have two small catheters (tubing) placed in their veins (I.V. lines). The total amount of blood that will be drawn during this test will be 140 mL of blood (approximately 9.5 tablespoons). Insulin is a natural hormone, and octreotide (a synthetic hormone) is a drug that temporarily blocks the secretion of insulin from your pancreas. A member of the research team is present and monitoring the results along with the nursing staff.
Study NCT06283173 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ColActive Plus Collagen Matrix Dressing
Description: Induction phase: Test article applied with Hill Top chamber every 48+ hours over 3 weeks. Rest phase: 10-day rest period with no application.~Challenge phase: Test article applied for 48 hours and evaluated through 48 hours post removal.~The positive control is evaluated at Induction 1 only. The negative control is applied following the same schedule as the test article.
Study NCT05312242 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) MMS
Description: Introduction of UNIMMAP MMS along with novel counseling strategies to increase acceptability and adherence to prenatal supplementation
Study NCT05312242 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Iron Folic Acid Supplement
Description: Standard of Care Intervention
Study NCT06063759 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: VitalDetect
Description: measurement of microcirculating blood flow, SpO2 (mmHg or %), heart rate (beats/min)
Study NCT05850247 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]DPA-714 PET
Description: To assess the association between plasma ficolin-2 levels and plaque and brain inflammation assessed by \[18F\]DPA-714 PET/MRI in patients managed for transient ischaemic attack or ischaemic stroke related to carotid stenosis.
Study NCT03995160 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Use of closed suction drainage following total knee arthroplasty
Description: Use of closed suction drainage following total knee arthroplasty
Study NCT03995160 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Abstain of using a closed suction drainage
Description: Abstain of using a closed suction drainage following total knee arthroplasty
Study NCT04699344 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: The level of CNV
Description: The extracted DNA from morning urine will be analyzed by PROUD to determine the level of CNV.
Study NCT05816824 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Symptom monitoring software via visual feedback
Description: With PhysioAnalyst software, individuals are evaluated using clinical tools (questionnaire, scale). These evaluations provide visual feedback to individuals in the form of tables and graphs. In this way, patients can observe the changes in their clinical status.
Study NCT05816824 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Symptom monitoring software via visual feedback
Description: With PhysioAnalyst software, individuals are evaluated using clinical tools (questionnaire, scale). These evaluations provide visual feedback to individuals in the form of tables and graphs. In this way, patients can observe the changes in their clinical status.
Study NCT06006871 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The Secret Trail of Moon (MOON): Cognitive training with Serious Video Game
Description: Patients are pharmacologically stable and receive a cognitive intervention with our videogame twice a week in the hospital (10 sessions) and twice a week in their home with a computer video game (other 10 sessions).
Study NCT06006871 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Usual treatment for ADHD
Description: All patients continue with their stable pharmacological treatment and do not receive any additional cognitive intervention.
Study NCT06006871 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Usual treatment for ADHD
Description: All patients continue with their stable pharmacological treatment and do not receive any additional cognitive intervention.
Study NCT05465525 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Quadratus Lumborum Block Type III
Description: Patients will receive ultrasound-guided quadratus lumborum block type III with 60 ml of bupivacaine 0.25% followed by general anesthesia.
Study NCT05465525 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Erector Spinae Plane Block
Description: Patients will receive ultrasound-guided erector spinae plane block type III with 60 ml of bupivacaine 0.25% followed by general anesthesia.
Study NCT05465525 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: No Block
Description: The patients will receive general anesthesia.
Study NCT04841954 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: hemp prick-test
Description: hemp seed and flower prick-test
Study NCT06110403 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TRIXEO AEROSPHERE
Description: BGF 160 (Breztri Aerosphere™ in USA, Trixeo™ in France) Inhalation aerosol: pressurized metered dose inhaler containing a combination of budesonide (160 mcg), glycopyrrolate (9 mcg) and formoterol fumarate (4.8 mcg) as an inhalation aerosol. Oral inhalation: 2 inhalations of BGF 160 twice daily for 30 days.
Study NCT05504759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: splint
Description: Resting is the first step of treatment in lateral epicondylitis. Patients will be given a 2 weeks rest protocol (works that may cause strain on the wrist and increase elbow pain will be described and it will be advised to stay away, and a home exercise program will be prepared, which includes the use of a resting splint during the daytime for 2 weeks). The goal of exercise therapy will be to stretch the muscles, strengthen them and maintain flexibility. Home exercises during the treatment of lateral epicondylitis will be beneficial when performed twice a day for at least three months, and stretching exercises will be performed first, and then strengthening exercises will be started in a controlled manner.
Study NCT05987345 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: PEF
Description: PEF device treated in the trial.
Study NCT05987345 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anti-PD-1 monoclonal antibody
Description: Anti-PD-1 monoclonal antibody administered on Day 7 then routinely.
Study NCT05504759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: steroid
Description: Betamethasone Dipropionate + Betamethasone Sodium Phosphate-1 ml will be administered once at the beginning of the study to patients who will receive steroid injection, one of the local injection treatments. Steroid injection will be applied to the most sensitive point on the lateral epicondyle. Afterwards, patients will be given a 2 weeks rest protocol (works that may cause strain on the wrist and increase elbow pain will be described and it will be advised to stay away, and a home exercise program will be prepared, which includes the use of a resting splint during daytime hours for 2 weeks). The goal of exercise therapy will be to stretch the muscles, strengthen them and maintain flexibility. Home exercises during the treatment of lateral epicondylitis will be beneficial when performed twice a day for at least three months, and stretching exercises will be performed first, and then strengthening exercises will be started in a controlled manner.
Study NCT05504759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: dry needling
Description: The needle will be guided to painful trigger points detected by palpation. Stainless steel 25x30 mm needles will be used for dry needling. Dry needle treatment will be applied to the painful trigger points in the forearm extensor group muscles with the stick-pull technique, 1 session per week, for a total of 2 sessions. Afterwards, the patients will be given a 2 weeks rest protocol (works that may strain the wrist and increase elbow pain will be described and it will be advised to stay away, and a home exercise program will be prepared, which includes the use of a resting splint during the daytime for 2 weeks). The purpose of exercise therapy will be to stretch the muscles, strengthen them and maintain flexibility. During the treatment of lateral epicondylitis, home exercises will be beneficial when performed twice a day for at least three months, and stretching exercises will be performed first, and then strengthening exercises will be started in a controlled manner.
Study NCT05415345 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Cecolin
Description: Bivalent HPV Vaccine
Study NCT05415345 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Cecolin
Description: Bivalent HPV Vaccine
Study NCT05415345 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Hecolin
Description: Hepatitis E vaccine
Study NCT05415345 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Hecolin
Description: Hepatitis E vaccine
Study NCT05510518 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: oral glucose tolerance test (OGTT)
Description: • The OGTT involves assessing fasting blood glucose, drinking a solution comprising 100 g of glucose, and three glucose tests at one, two, and three hours following glucose load.
Study NCT05314361 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 1-Day Cognitive Behavioural Therapy-Based Workshop
Description: The Online Workshop is a day-long intervention delivered by two trained public health nurses consisting of 6 hours of instruction delivered in 4 modules. The 1st contains information on PPD etiology with a focus on modifiable cognitive risk factors (e.g., negative thoughts, maladaptive core beliefs). The 2nd module focuses on cognitive skills including cognitive restructuring. The 3rd builds behavioural skills such as problem solving, behavioural activation, assertiveness, sleep strategies, and using supports. The final module provides an opportunity for goal setting/action planning. Teaching methods include didactic sections, group exercises, and role-plays. Regular breaks are incorporated. Each participant is given a professionally designed manual to facilitate learning. We also provide a list of region-specific PPD resources and a copy of the Canadian Practice Guidelines for the treatment of PPD (written by the NPA).
Study NCT06211699 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Omentopexy with Laparoscopic Sleeve Gastrectomy
Description: Patients with omentum sewed to the remnant gastric staple line during laparoscopic sleeve gastrectomy.
Study NCT06211699 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Clips with Laparoscopic Sleeve Gastrectomy
Description: Patients performed clips to the remnant gastric staple line during laparoscopic sleeve gastrectomy
Study NCT05013554 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR443216 IV
Description: Pharmaceutical form: Powder for solution; Route of administration: IV infusion
Study NCT05013554 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SAR443216 SC
Description: Pharmaceutical form: Powder for solution; Route of administration: SC injection
Study NCT06362460 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C] RAY1216
Description: 400 mg suspension containing 100μCi of \[14C\]RAY1216
Study NCT05389059 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: CAF+CM
Description: Periodontal surgery including CAF+CM application
Study NCT05389059 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: I-PRF
Description: Periodontal surgery including CAF+CM application with i-PRF
Study NCT05010629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 9-ING-41
Description: Intravenous infusion
Study NCT05010629 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Intravenous infusion
Study NCT04526119 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acotiamide hydrochloride hydrate
Description: A white film-coated tablet containing 100 mg Z-338 Administered orally, one tablet a time and three times a day before meals for 28 days in the double-blind phase Administered orally, one tablet a time and three times a day before meals for 28 days in the open-label phase
Study NCT04526119 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A white film-coated tablet not containing 100 mg Z-338 Administered orally, one tablet a time and three times a day before meals for 28 days in the double-blind phase
Study NCT04721977 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tucatinib
Description: Tucatinib 300 mg administered BID via oral tablet
Study NCT04721977 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: Trastuzumab 8 mg/kg loading dose followed by 6 mg/kg maintenance dose, administered via IV infusion
Study NCT04721977 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Description: Capecitabine 1000 mg/m\^2 administered BID via oral tablet
Study NCT05902429 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cladribine 10 mg oral tablet
Description: Cladribine tablets (Mavenclad®, Merck KGaA, Darmstadt, Germany) will be given according to the label with a cumulative dose of 3.5 mg/kg body weight distributed over 2 years as one treatment course of 1.75 mg/kg per year. Each treatment course will consist of 2 weeks of treatment, one at the beginning of the first month and one at the beginning of the second month of the respective year of treatment. Each treatment week will consist of 4 or 5 days in which the participant will receive 10 mg or 20 mg (1 or 2 tablets, respectively) as a single daily dose, depending on body weight, according to the tables available in label. Upon completion of the two treatment courses, no further courses will be required in years 3 and 4.
Study NCT04918303 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: SKNA recording
Description: The coupled recording of the sympathetic nervous activity of the skin and of an ECG will be carried out using the ME6000 device, CE marked, from the Bittium company.~It will be performed for a maximum period of one hour at Day 1, Post-procedure between Day 1 and discharge from hospital, and month 6
Study NCT05089474 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Streamline Surgical System
Description: The Streamline System is a device that delivers viscoelastic into Schlemm's Canal.
Study NCT04874675 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: diclofenac / acetaminophen /codeine
Description: routine pain medication used post extraction of third molars
Study NCT04874675 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ibuprofen/acetaminophen/codeine
Description: routine pain medication used post extraction of third molars
Study NCT06464432 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Enhanced Skills Training in Affective and Interpersonal Regulation
Description: Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR); Psychotherapeutic manual for the treatment of Complex Post-Traumatic Stress Disorder (CPTSD) consisting of 4 therapeutic modules: 1. Emotion Regulation, 2, Self-concept, 3. Relationship Patterns, 4. Prolonged Exposure.
Study NCT06010862 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA CAR-T cells
Description: After lymphodepletion with Fludarabine and Cyclophosphamide,CAR T cells were transfused intravenically
Study NCT06010862 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CEA CAR-T cells
Description: After lymphodepletion with Fludarabine and Cyclophosphamide,CAR T cells were injected intraperitoneally
Study NCT04962503 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Afamelanotide
Description: Six adult patients with clots located in the higher segments of the brain and who are ineligible for alternative treatments will be enrolled in the study and evaluated for six weeks. The study will assess patients' brain injury with computed tomography (CT) scans and magnetic resonance imaging (MRI), as well as using recognised methods of clinical evaluation to measure changes in patients' neurological and cognitive function following treatment.
Study NCT06280248 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Endoscopic ultrasound guided cystogastrostomy of symptomatic pancreatic pseudocyst
Description: The technical success rates, clinical success rates, and potential complications of the different endoscopic ultrasound-guided techniques for the best drainage of pancreatic fluid collections (PFCs) as regard type, caliber, and number of plastic stents and the ideal timing for stent removal will be assessed.~Also compare early vs. late intervention for complete endoscopic necrosectomy of walled off pancreatic necrosis (WOPN ) as regard to technical success rates, clinical success rates, potential complications, and the number of sessions needed will be done.~In order to evaluate total resolution or a reduction in cyst diameters with clinically significant improvement in symptoms, patients will be monitored for one month and six months following the insertion of the stent.