AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06266767 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Levobupivacaine and Fentanyl
Description: Programmed Intermittent Epidural Bolus
Study NCT05306730 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ECHOcardiography, Point-of-Care UZ
Description: Emergent echocardiography is reproducible method providing clinically significant information during primary survey of acute cardiovascular diseases. Possible benefit is the risk stratification of acute non-stemi coronary syndromes and differentiation from other serious conditions, such as pulmonary embolism or aortic dissection. The aim of interest is to consider riscs and benefits of the ultrasound of heart done by non-cardiologist after standardized course.
Study NCT05816850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EZH2 mutations/CNAs by droplet digital PCR (ddPCR)
Description: Test of EZH2 mutations/CNAs by droplet digital PCR (ddPCR) in peripheral blood and in unsorted bone marrow aspirate samples at enrolment
Study NCT05816850 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: EZH2-derived gene expression signature by RNA-Seq
Description: Test of EZH2-derived gene expression signature by RNA-Seq in a subset of diagnostic FFPE samples
Study NCT05873868 — intervention group
Intervention type: OTHER
Intervention: Six minutes walk test
Description: Six minutes walk test just before first intake of treatment and after 1 and 2 years
Study NCT05873868 — intervention group
Intervention type: OTHER
Intervention: Kansas City questionnaire
Description: Kansas City questionnaire just before first intake of treatment and after 1 and 2 years
Study NCT05873868 — intervention group
Intervention type: OTHER
Intervention: COMPASS31 self questionnaire
Description: Compass31 self questionnaire assessing dysautonomia just before first intake of treatment and after 1 and 2 years
Study NCT05884658 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: vNOTES : natural vaginal orifice transluminal endoscopic system for hysterectomies
Description: hysterectomy via the vaginal approach by vNOTES (natural vaginal orifice transluminal endoscopic system for hysterectomies)
Study NCT05884658 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: laparoscopic hysterectomy
Description: laparoscopic hysterectomy uses a standardized procedure with or without surgical robot
Study NCT06407817 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spencer technique
Description: No of repetitions; 3 sets for 10 repetitions with 1 minute rest between sets No Of Sessions Per Week: 3 Per Weeks for 6 weeks (40 Min per Session)
Study NCT06407817 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Spencer technique
Description: No of repetitions; 3 sets for 10 repetitions with 1 minute rest between sets No Of Sessions Per Week: 3 Per Weeks for 6 weeks (40 Min per Session)
Study NCT06407817 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: reverse distraction technique
Description: No of repetitions; 10 ( Shoulder Abduction)10 ( Shoulder Flexion) 10 (Shoulder External Rotation) No Of Sessions Per Week: 3 Per Weeks for 6 weeks (40 Min Per Session)
Study NCT06407817 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: reverse distraction technique
Description: No of repetitions; 10 ( Shoulder Abduction)10 ( Shoulder Flexion) 10 (Shoulder External Rotation) No Of Sessions Per Week: 3 Per Weeks for 6 weeks (40 Min Per Session)
Study NCT05728723 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Android Application
Description: Android Application for 3 months
Study NCT05728723 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pharmacy education
Description: Pharmacy education in hypertensive patients
Study NCT05728723 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pharmacy education
Description: Pharmacy education in hypertensive patients
Study NCT06166927 — intervention group
Intervention type: DEVICE
Intervention: Cuffed endotracheal tube
Description: Patients will be intubated using a cuffed ETT with its OD determined by US measurement of the epiphyseal diameter of the distal radius.
Study NCT06166927 — intervention group
Intervention type: DEVICE
Intervention: UnCuffed ETT
Description: Patients will be intubated using an uncuffed ETT (Flexicare-UK) with its OD determined by US measurement of the epiphyseal diameter of the distal radius.
Study NCT05189977 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Propranolol
Description: Propranolol (tablet, oral ): 40 mg QD Day 3 and Day 21~Intervention 1 is a single dose of prazosin administered in the presence of sertraline alone at steady state or in the presence of sertraline + brexpiprazole at steady state.
Study NCT05189977 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Prazosin
Description: Prazosin (tablet, oral): 1 mg QD Day 2 and Day 20~Intervention 2 is a single dose of propranolol administered in the presence of sertraline alone at steady state or in the presence of sertraline + brexpiprazole at steady state.
Study NCT05374837 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Infant and young child feeding voice messaging intervention
Description: A mobile voice and text messaging intervention aimed at improving IYCF practices will be delivered to mothers and fathers with young children (6-23 months). A total of 16 voice and text message, with the same content, will be sent over a 16-week period (1 voice + 1 text messages (with same content) per week x 16 weeks). Two types of messages will be included: 1) eight scripted and 2) eight unscripted messages from positive deviants. The content of the messages include: breastfeeding until two years of age, consuming a variety of foods within a given meal, the consistency of porridge (thick rather than thin), limiting sweets and fried foods, the importance of animal source foods, consuming vitamin A rich fruits and vegetables, consuming leafy greens, handwashing and feeding infants and young children fruits and vegetables produced by the household.
Study NCT05311956 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Active tDCS
Description: The study intervention will be participants self-applying 40 tDCS active stimulations with in-person supervision provided by trained study personnel. The self-applied intervention will continue 5 times per week over eight consecutive weeks. Treatment will occur in the home.
Study NCT05311956 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham tDCS
Description: In this arm of the study participants will self-apply 40 sham tDCS stimulations with in-person supervision provided by trained study personnel. The self-applied intervention will continue 5 times per week over eight consecutive weeks. Treatment will occur in the home.
Study NCT05757063 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sedation with propofol
Description: After spinal anesthesia, patients will be sedated with propofol.
Study NCT05757063 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: sedation with dexmedetomidine
Description: After spinal anesthesia, patients will be sedated with dexmedetomidine.
Study NCT05731414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioural Therapy for Psychosis (CBTp)
Description: Individual formulation-based CBT will be delivered for one hour per week using a manual that has been validated in over 1000 individuals with schizophrenia-spectrum disorders across all stages of illness. This approach has demonstrated moderate to large improvements on symptoms and small to moderate effects on functioning. The first four sessions are devoted to building therapeutic rapport and developing collaborative treatment goals. The following phase focuses on developing formulations of why difficulties persist and using cognitive and behavioural change strategies. A longitudinal formulation is then offered to better understand how their difficulties developed. The final 2-4 sessions focus on consolidating the learning that occurred during treatment so that participants can maintain their improvement. Therapy homework is collaboratively assigned at the end of sessions to promote new learning in between sessions.
Study NCT05731414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Remediation Therapy (CR)
Description: Action-based cognitive remediation (ABCR) will be delivered in group sessions one hour per week. ABCR was developed by Dr. Bowie (CI) and Dr. Best (PI) and has been found efficacious for schizophrenia-spectrum disorders in three clinical trials. ABCR involves practicing computerized training exercises with difficulty level dynamically titrated to improve neurocognitive abilities. Then participants engage in strategy discussions with other group members to develop new cognitive strategies. Finally, participants complete role-play simulations of real-world activities to practice their cognitive strategies in simulations of everyday life. ABCR is more effective for improving functioning than traditional approaches to CR. Homework consists of additional cognitive training and practicing cognitive strategies in everyday life.
Study NCT05731414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Befriending
Description: Befriending will be delivered according to a manual validated to control for the non-specific effects of CBT, such as duration of therapeutic contact, client expectancy effects, therapeutic alliance, and therapist warmth. Befriending consists of 1-hour individual sessions once per week and involves a series of conversations similar to those one might have with a social acquaintance. These conversations involve discussion of neutral topics without problem-solving, coping strategies, or exploration of emotion. If emotional or mental health-related topics are brought up therapists redirect back to a neutral topic.
Study NCT05731414 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sham Cognitive Remediation
Description: Sham CR was developed by Dr. Best and Dr. Bowie (CI) to control for the non-specific effects of CR such as computer practice and group discussion. Participants practice similar computerized exercises to ABCR, however, the exercises do not increase in difficulty. Participants then discuss enjoyment of the exercises but any discussion of cognitive strategies is redirected back to a neutral topic. We have previously found this condition to be an effective control for CR, with similar engagement to the active training group.
Study NCT06310278 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Ossicular mobility measurement
Description: Measurements of ossicular mobility i.e. the dynamic velocity of middle ear structures (umbo of malleus and incus at the incudostapedial joint) normalized to sound pressure incident on the tympanic membrane.
Study NCT05254288 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chlorhexidine
Description: In-office and domiciliary use of chlorhexidine for 14 days.
Study NCT05254288 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ozoral gels
Description: In-office administration of Ozoral Pro and domiciliary use of Ozoral gel for 14 days.
Study NCT06546280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Camrelizumab
Description: Camrelizumab 200 mg will be administered by IV infusion on Day 1 of each 21-day cycle.
Study NCT05981105 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ambIT pump with catheter
Description: 0.2% ropivacaine will be infused through a catheter pump at a rate of 10 ml/hr, 600 ml reservoir.
Study NCT05981105 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: ambIT pump with sham catheter
Description: sham catheter with no infusion
Study NCT06361147 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Psychoeducational program for ASD
Description: 6 psychoeducation trainings for Autism Spectrum Disorder
Study NCT06509919 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood draw
Description: Before undergoing a prostate biopsy, participants will have about 10 mLs of venous blood drawn. Blood will be sent to Geneseeq Technology Inc. for whole genome high-throughput sequencing of plasma cfDNA.
Study NCT06392776 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Early diagnosis and treatment
Description: Early diagnosis of previously undiagnosed asthma or COPD and subsequent treatment by a primary care practitioner
Study NCT04060355 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Savvy program
Description: Caregiver program (Savvy) is an evidence-based dementia family caregiver psychoeducation program. Provided to groups of 8-12 (typically) individuals caring for family members living with Alzheimer's disease or related dementias (PLWD), Savvy employs a mechanism of action based in Social Cognitive theory to promote caregivers' solution-focused coping behaviors through the acquisition of appropriate knowledge, skills, and outlook and the enhancement of caregiving mastery.
Study NCT04060355 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Semi-structured video interviews
Description: Semi-structured video interviews will assess the preliminary efficacy of programs led by system-trained interventionists in producing anticipated outcomes in caregiver participants - reduced depression and burden and enhanced caregiving mastery. It will also focus on sense of the completeness and adequacy of the training program, including the training methods, videos, and materials
Study NCT05369065 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Ablation Treatment
Description: Denervation of renal and common hepatic arteries by ethanol ablation with the Neurotronic Infusion Catheter
Study NCT05369065 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: SHAM_COMPARATOR
Intervention: Arterial Angiography Only
Description: Arterial Angiography Only without Intervention
Study NCT05369065 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Single Arm non-Randomized Ablation Treatment
Description: Denervation of renal and common hepatic arteries by ethanol ablation with the Neurotronic Infusion Catheter
Study NCT06546280 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Apatinib
Description: Apatinib 250 mg will be taken orally once daily.
Study NCT06045481 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: administration of single dose of doxycycline
Description: Postexposure prophylaxis with Single Dose doxycycline
Study NCT03887741 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Plasmapheresis
Description: Patient will have monthly plasma exchange with young ApoE 33 plasma. Each exchange will be 1.5 volume of patient's plasma
Study NCT03887741 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Plasma infusion
Description: Infuse every two weeks with ApoE33 young plasma (1unit) for 6 months
Study NCT05468905 — intervention group
Intervention type: OTHER
Intervention: None of intervention
Description: None of intervention
Study NCT06132113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BI 764532
Description: BI 764532
Study NCT06132113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carboplatin
Description: Standard of care
Study NCT06132113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etoposide
Description: Standard of care
Study NCT06132113 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Standard of care
Study NCT04758312 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: MY-Skills Mobile
Description: Yoga and Self-Management Education
Study NCT06577701 — intervention group
Intervention type: DRUG
Intervention: traditional Chinese medicine (TCM)
Description: Regulated use of Chinese medicine treatment protocols is included as an exposure factor. Exposure was defined as taking the medication continuously for more than 3 months per year, or taking the medication intermittently for more than 6 months per year. According to the standardised use of TCM protocols, the group was divided into an exposed group (TCM protocols cohort) and a non-exposed group (non-TCM protocols cohort).
Study NCT06577701 — intervention group
Intervention type: DRUG
Intervention: non traditional Chinese medicine (non-TCM)
Description: Regulated use of Chinese medicine treatment protocols is included as an exposure factor. Exposure was defined as taking the medication continuously for more than 3 months per year, or taking the medication intermittently for more than 6 months per year. According to the standardised use of TCM protocols, the group was divided into an exposed group (TCM protocols cohort) and a non-exposed group (non-TCM protocols cohort).
Study NCT06171087 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Domperidon
Description: oral
Study NCT06171087 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: oral tablet
Study NCT05414656 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Saddle contoured metal matrix, Pre-contoured self-adhesive matrix
Description: Saddle contoured metal matrix placed with the small clipper. The -contoured self-adhesive matrix has self adhesive ability.
Study NCT05414656 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Saddle contoured metal matrix, Pre-contoured self-adhesive matrix
Description: Saddle contoured metal matrix placed with the small clipper. The -contoured self-adhesive matrix has self adhesive ability.
Study NCT04910061 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Nicotinamide mononucleotide (NMN-C)
Description: Daily supplementation with NMN-C at 400 mg for 29 days in total
Study NCT06296771 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Dietary energy restriction group (D)
Description: The participants allocated to the dietary energy restriction group will receive instructions to change their usual dietary intake and maintain their regular physical activity routine for the duration of eight weeks.~The dietary energy restriction depends on a total calorie deficit of 5000 kcal per week, achieved by the consumption of reduced meal portions. This deficit is computed by subtracting the participants\&#39; energy expenditure, as measured by ActiheartTM, rather than relying on reported energy intake. This approach is employed to reduce potential difficulties arising from participants under-reporting their food consumption. The energy deficit is calculated by multiplying the weight of each food item recorded over a 5-day period by an individual factor obtained from energy expenditure data. This calculation enables the determination of the required energy intake for the intervention period.
Study NCT06269796 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Little Developmental Coordination Disorder Questionnaire (LDCDQ)
Description: The Little Developmental Coordination Disorder Questionnaire (LDCDQ) is a parent questionnaire consisting of 15 items designed to screen for motor coordination difficulties in 3- and 4-year-old children. It comprises 15 items grouped into two distinct factors: gross motor skills and fine motor skills. A Likert scale is used, ranging from one to five, where one (1) indicates Not at all like your child and five (5) indicates Very much like your child. The total of the 15 items is added up to obtain a total score of 75.
Study NCT05080166 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview with Clinicians
Description: One time, qualitative interview of clinicians for feedback on UPLYFT intervention
Study NCT05080166 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Field Test of UPLYFT with Lymphoma Survivors
Description: 6 session of UPLYFT intervention with Lymphoma Survivors for feedback
Study NCT05080166 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pilot of UPLYFT with Lymphoma Survivors
Description: 6 session of UPLYFT intervention with Lymphoma Survivors
Study NCT06269796 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Bruininks- Oseretsky Test of Motor Proficiency 2nd Edition (BOT-2)
Description: The BOT-2 is standardized for children and adolescents aged 4 to 21 years and 11 months, and the full test takes 45 to 60 minutes to perform. The BOT-2 test was used to detect deviation from the norm and the likelihood of a diagnosis for DCD. The BOT-2 measures fine and gross motor proficiency, with subtests focusing on stability, mobility, strength, coordination, and object manipulation.
Study NCT04946097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: gross Myofascial Release
Description: Gross Myofascial Release : is amanual technique in form of Stretch of the Posterior Cervical Musculature and Gross stretch of gross Myofascial Release upper quarter: Arm Pull for duration of 10-15 min per session each stretch position was healed for 90sec
Study NCT04946097 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: conventional selected exercise program
Description: stretching exercises for cervical muscles and pectoralis major and source of heat in form of hot packs for 15 minutes
Study NCT04946097 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Transcutaneous electrical nerve stimulation (TENS)
Description: Transcutaneous electrical nerve stimulation (TENS) is a method of pain relief involving the use of electrical current, the electrode placement on the course of pain for 15 minutes
Study NCT06213766 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive assessment
Description: Group 1: Cognitively healthy subject:~After signing the consent form, during the only visit of the study, the investigator will administer to cognitively healthy subjects two cognitive screening tests to ensure that they meet the criteria for group 1. If performance on the cognitive scales prove to be borderline or below current standards (Montreal Cognitive Assessment ≥ 26/30 and MacNair Cognitive Difficulties Self-Rating Scale ≥15) for at least one of the 2 tests, the participant will prematurely end the study and may be offered an in-depth cognitive assessment as part of routine care.~Group 2: Patients suffering from Alzheimer's disease:~After signing the consent form, during the only visit of the study, the investigator will administer to patients the Montreal Cognitive Assessment to assess cognitive status.