AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05567601 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DOXIL/CAELYX
Description: 40 mg/m2 as a 90-minute IV infusion via a central venous catheter or peripheral vein
Study NCT05585268 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Medication reconciliation supplemented with MedSafer and deprescribing brochures
Description: This unit will act as an intervention unit for the MedRec where MedSafer deprescribing reports will be handed to the treating team and deprescribing brochures from the Canadian Deprescribing Network will be given to patients.
Study NCT05103085 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Rapid diagnostic orientation test (TROD) for Hepatitis C
Description: Inclusion of patients during the consultation with the gastroenterologist, before hospitalization in the digestive endoscopy department. Each consenting patient benefits from a HCV screening using TROD on the day of their hospitalization in the department.
Study NCT05854316 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Comprehensive Biomechanical assessment
Description: Magnetic resonance images, electromyography and dynamometry data will be used, together with data from the gait assessment and clinical questionnaires/measures, to characterize the biomechanics of the participants, and to develop and inform personalised musculoskeletal models
Study NCT02920762 — intervention group
Intervention type: OTHER
Intervention: on-interventional study - retrospective database review
Study NCT05179889 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mFOLFIRINOX
Description: Irinotecan 150 mg/m2 IV day 1, oxaliplatin 85 mg/m2 IV day 1, Leucovorin 400 (or levoleucovorin 200) mg/m2 IV day 1, 5-FU 1200 mg/m2/d IV x 2 days (total 2400 mg/m2 over 48 hours) continuous infusion\] 12 cycles per 2 weeks~mFOLFOX 6 \[Oxaliplatin 85 mg/m2 IV day 1, Leucovorin 400 (or levoleucovorin 200) mg/m2 IV day 1, 5-FU 400 mg/m2 IV bolus day 1, 5-FU 1200 mg/m2/d IV x 2 days (total 2400 mg/m2 over 46-48 hours) continuous infusion, 12 cycles per 2 week
Study NCT05179889 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: mFOLFOX 6
Description: Oxaliplatin 85 mg/m2 IV day 1, Leucovorin 400 (or levoleucovorin 200) mg/m2 IV day 1, 5-FU 400 mg/m2 IV bolus day 1, 5-FU 1200 mg/m2/d IV x 2 days (total 2400 mg/m2 over 46-48 hours) continuous infusion, 12 cycles per 2 weeks
Study NCT05420701 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TEE
Description: Patients in the surgical arm (LAAC) will be arranged to do TEE, which is not considered standard of care.
Study NCT05457686 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: kinesio tape
Description: According to this, the proximal part of the band is located close to the lymph node. In our study, as stated in the literature, the proximal part of the tape will be adhered to the fibular head area next to the lymph nodes without applying any stretching. Then 5-10% stretching is applied and the distal part is adhered. 2 separate tapes are applied so that the strips cross each other
Study NCT05457686 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham taping
Description: In the same procedure and time as kinesiotaping, inelastic tape will be used instead of kinesiotape.
Study NCT05457686 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise
Description: Routine exercise and physiotherapy program applied after knee arthroplasty surgery will be applied
Study NCT05457686 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Exercise
Description: Routine exercise and physiotherapy program applied after knee arthroplasty surgery will be applied
Study NCT05457686 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Exercise
Description: Routine exercise and physiotherapy program applied after knee arthroplasty surgery will be applied
Study NCT05643937 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Routine health education
Description: The control group received routine health education after catheterization, including introducing the purpose, method, advantages and complications of PICC insertion to patients before catheterization and signing informed consent. During catheterization, PICC assistant explained relevant matters needing attention and cooperative actions to the patient. After catheterization, patients were instructed to carry out grip training and limb activities.
Study NCT05643937 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Routine health education + precise health education
Description: On the basis of routine health education in the control group, the experimental group screened the high-risk behaviors of patients through the questionnaire of daily life behavior habits, and formulated the precise and concrete health education program for their high-risk behaviors
Study NCT04133701 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Time-Restricted Feeding
Description: After baseline measurements have been completed, participants will enroll in a time-restricted feeding intervention. Participants will be asked to restrict the time in which they eat each day to 10 hours, fasting for the remaining 14 hours. Participants will also be asked to finish their last meal of the day at least 2 hours prior to bedtime.
Study NCT05666037 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobile health intervention(mHealth)
Description: The intervention group will receive mobile health messaging intervention on behavior change to uptake early postpartum modern contraceptive method.
Study NCT05727280 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Progressive Relaxation Exercise Practices
Description: The intervention planned within the scope of the research are the Progressive Relaxation Exercise application. Patients in the intervention group undergoing open heart surgery will be given training on progressive relaxation exercise in the patient's room the day before the surgery. Correct breathing techniques will be taught and the relaxation exercises will be performed by using audio recordings. Afterwards, the relaxation exercise will be provided to the patient to practice the progressive relaxation exercise with mp3 accompaniment. After open heart surgery, progressive relaxation exercise will be applied to the patient on the 1st, 2nd and 3rd days of his admission to the service. The patient will be asked to perform the progressive relaxation exercise twice a day, once during the day and once in the evening.
Study NCT05203419 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MHS552
Description: MHS552 will be administered once weekly as subcutaneous injection for 4 weeks (Part A) or 12 weeks (Part B)
Study NCT05203419 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo will be administered once weekly as subcutaneous injection for 4 weeks (Part A) or 12 weeks (Part B)
Study NCT06330077 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ifenprodil
Description: Treatment administration
Study NCT06330077 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Treatment administration
Study NCT06177509 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Graded Aerobic Exercise
Description: Participants will follow a sub-symptom aerobic exercise program (approx. 30 min) 3 - 5 times pr week for twelve weeks. Sub-symptom threshold aerobic exercise means to exercise at 80-90% of the maximum threshold heart rate achieved during the BCTT. To ensure proper exercise dose and progression, participants will be retested every three weeks. During the first three weeks, the participants will be offered one weekly guided exercise session. The other 2 - 4 weekly sessions the participants will carry out on their own, choosing activities based on experience, preferences and possibilities (e.g. walking, jogging, stationary bike, swimming). The intensity of the sub-symptom threshold aerobic exercise will be monitored using a heart rate monitor and the BORG scale. Compliance with the sub-symptom threshold aerobic exercise program will be recorded by the patients in an exercise diary, which is followed up by a weekly reminder over the phone/sms by a physiotherapist in the project.
Study NCT04427540 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxytocin
Description: Oxytocin 10 micrograms IM
Study NCT04773587 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Roflumilast Cream 0.15%
Description: Roflumilast Cream 0.15% - Active
Study NCT04773587 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle Cream
Description: Cream - Vehicle
Study NCT05509972 — intervention group
Intervention type: DEVICE
Intervention: total knee prosthesis implantation
Description: Total Knee Arthroplasty (TKA) represents a well-established, reliable and successful treatment option for end-stage bicompartmental osteoarthritis or comparable conditions even in young patients compromised by knee pain and limitations of daily living
Study NCT04632628 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
Description: Participants will complete 4 web-based CBT- I sessions. Lesson 1: Sleep Hygiene and Stimulus Control Lesson 2: Sleep Restriction and Relaxation Strategies Lesson 3: Identifying and Restructuring Dysfunction Thoughts Lesson 4: Practical Recommendations, Review, and Maintenance of Change
Study NCT04559217 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Radiopharmaceutical 68Ga-DOTATATE
Description: Injection of 68Ga-DOTATATE followed by PET/CT acquisition
Study NCT06346054 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Breath analysis
Description: Detection of proteins and volatile organic compounds (oncometabolites) in the exhaled breath
Study NCT06346054 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Breath analysis
Description: Detection of proteins and volatile organic compounds (oncometabolites) in the exhaled breath
Study NCT06346054 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: Blood analysis
Description: Detection of proteins and circulating tumor DNA (oncometabolites) in the peripheral blood
Study NCT06346054 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood analysis
Description: Detection of proteins and circulating tumor DNA (oncometabolites) in the peripheral blood
Study NCT06421623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Program Including Various Workshops aiming to preserve elderly's autonomy through foot health
Description: Combination of minimalist footwear, foot massages, and workshops to re-learn walking and posture
Study NCT06394921 — intervention group
Intervention type: PROCEDURE
Intervention: 2 day cardiopulmonary exercise test
Description: Consecutive day 2 day CPET and follow up for 7 days for subjective feelings/fatigue.
Study NCT05743686 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Application
Description: The participants will have access to an app allowing them to report their adverse effects to oral chemotherapy. Basic advices will be given and the hospital pharmacists will be warned.
Study NCT05741983 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Microfracture (MFx)
Description: The ankle arthroscopy will be a standard procedure. The lesion will be identified, measured and prepared with curettage and soft tissue shaver. Preparation includes debridement of the unstable cartilage and in case of a chondral defect associated with a bone defect, the subchondral cyst is debrided. After debridement, the defect is classified and the lesion size is measured again.The microfracture will be performed with a microfracture awl. In cases of a chondral defect associated with a bone defect (osteochondral defect) the bone lesion must be treated concomitantly. Portal closure will be with steri-strips. All patients will follow the standard postoperative rehabilitation protocol including post op non-weight bearing and range of motion exercises for 6 weeks.
Study NCT05741983 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Microfracture (MFx)
Description: The ankle arthroscopy will be a standard procedure. The lesion will be identified, measured and prepared with curettage and soft tissue shaver. Preparation includes debridement of the unstable cartilage and in case of a chondral defect associated with a bone defect, the subchondral cyst is debrided. After debridement, the defect is classified and the lesion size is measured again.The microfracture will be performed with a microfracture awl. In cases of a chondral defect associated with a bone defect (osteochondral defect) the bone lesion must be treated concomitantly. Portal closure will be with steri-strips. All patients will follow the standard postoperative rehabilitation protocol including post op non-weight bearing and range of motion exercises for 6 weeks.
Study NCT05741983 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Chondro-Gide®
Description: After the microfracture is performed and before the concomitant treatment of a bony lesion (if present), the defect size will be templated, and the membrane cut into its correct size. The joint is then drained and the membrane will be applied over the defect and stabilised with Fibrin glue. In cases of a osteochondral defect the bone lesion must be treated concomitantly. Once the bone defect has been treated, the Chondro-Gide® membrane is used to cover the site, and to support new cartilage tissue formation at the joint interface. Fluid will be reintroduced, and the stability of the membrane will be confirmed arthroscopically.
Study NCT04765254 — intervention group
Intervention type: OTHER
Intervention: no intervention as it is an observational study
Description: both groups will be monitored for the disease progress or deterioration and mortality rate
Study NCT04539509 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Prescription
Description: A specific exercise prescription, based on the results of a treadmill test.
Study NCT04539509 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Treadmill Test
Description: A symptom-limited treadmill test, using the Buffalo Concussion Treadmill Test (BCTT) protocol.
Study NCT04539509 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treadmill Test
Description: A symptom-limited treadmill test, using the Buffalo Concussion Treadmill Test (BCTT) protocol.
Study NCT04539509 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Monitoring
Description: Activity monitoring using a Fitbit.
Study NCT04539509 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Monitoring
Description: Activity monitoring using a Fitbit.
Study NCT04539509 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Monitoring
Description: Activity monitoring using a Fitbit.
Study NCT06249217 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Good Nights Sleep Program
Description: The Good Nights Sleep Program arm adapts established evidence-based motivational practices to change child and family sleep environments and sleep hygiene practices. At Week 0, participants will provide a comprehensive assessment of sleep environment and sleep hygiene practices and will be issued a Fitbit watch to wear for the duration of the study. At Week 2, participants will receive information about the benefits of good sleep, feedback about their sleep environment and sleep hygiene practices based on the Week 0 assessment data to implement at home, and sleep environment modification items based on participant-identified areas of need (e.g., a fan, sound machine, bedding). At Week 4, families in the Good Nights Sleep Program arm will provide post-intervention assessment data and feedback on the intervention and families in the Waitlist-Control arm can elect to receive the intervention if they choose to.
Study NCT06285058 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: No interventions
Description: The high-throughput extraction of large amounts of quantitative image features from medical images
Study NCT05375682 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated care program
Description: Core Component 1: Fostering Collaboration and Capacity Core Component 2: Streamlined communication process for referrals and care planning Core Component 3: Coordinated Care Conferences
Study NCT04867226 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Colchicine 0.5 MG
Description: participant will be given a Colchicine regimen in a dose of 0.5mg twice daily for 14 days or until symptoms subsides,those with low body weight and develop side effect like diarrhea and vomiting dose will be reduced and supportive treatment will be given .
Study NCT04867226 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: usual care treatment
Description: control group will receive usual care COVID-19 treatment according to Iraqi protocol guideline and will not receive colchicine.
Study NCT05813249 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rybelsus Oral Product
Description: Oral Semaglutide
Study NCT06386666 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Disposable fibrous ring sutures
Description: A new disposable fibrous ring suture device developed and produced by 2020 (Beijing) Medical Technology Co., Ltd
Study NCT06568250 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: RAMP program
Description: The RAMP program is a 12-week virtual program consisting of an individual session (50 minutes) with a Whole Health Coach followed by 11 weekly interactive group sessions (90 minutes each) with pre-recorded expert led education videos, mind-body skill training and practice, and facilitated discussions.
Study NCT05555186 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BWL classrooms (Experimental)
Description: Adolescents in the BWL classrooms will be exposed to the circadian stimulating bright light (600-1000lx) to maintain alertness. The programming of the LED lighting system in the intervention group (BWL) will be tuned to provide equal stimuli to the cone and melanopsin-containing photoreceptors measured at the eye height (1.2 m above floor level for sitting position) approximately in the range 4500 -5500 K (cool white light) or between 600 and 1000 lx.
Study NCT05555186 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: DWL classrooms (Comparison)
Description: Participants in DWL classrooms will receive conventional light from the same kind of equipment as used for the intervention group, only not applying high circadian stimulation(300lx). In order to replicate conventional lighting in the classrooms, the programming of the new LED lighting system in the control group (DWL) will meet the minimum requirements according to EN12464-181, or at least 300 lx measured at table height for a light source rated at 3000 K (warm white light).
Study NCT05355831 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active Transcranial Direct Current Stimulation
Description: See arm/group description
Study NCT05355831 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham stimulation
Description: See arm/group description
Study NCT04624841 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Indocyanine Green
Description: 2.5-7.5 mg (0.05 mg/kg) injection
Study NCT02968641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lonafarnib
Description: antiviral farnesyltransferase inhibitor
Study NCT02968641 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ritonavir
Description: CYP 3A4 inhibitor, lonafarnib booster
Study NCT06521281 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Chan-Chuang qigong
Description: Twice daily, every 15 minutes Chan-Chuang qigong
Study NCT06204276 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Experimental: Asymmetrical high-flow nasal cannula
Description: Asymmetrical high-flow nasal cannula will be set at 40 and 60 L/min in a random order. Temperature will be set at 37 degree celsius and inspired oxygen fraction (FiO2) will be adjusted to maintain oxygen saturation by pulse oximetry (SpO2) >/= 94% in acute hypoxemic patients and between 92-94% in acute hypercapnic COPD patients
Study NCT06204276 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Active comparator: Conventional high-flow nasal cannula
Description: Conventional high-flow nasal cannula will be set at 40 and 60 L/min in a random order. Temperature will be set at 37 degree celsius and FiO2 will be adjusted to maintain SpO2 >/= 94% in acute hypoxemic patients and between 92-94% in acute hypercapnic COPD patients
Study NCT05439759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Condition 1: Training visual sensitivity
Description: Investigators adopt a standard PL approach to train early visual processes of discriminating the orientation of Gabor patches presented at threshold contrast. Across training blocks, Gabors will range in spatial frequency, where contrast is adapted with a 3/1 staircase. Whenever a specific contrast threshold is reached, spatial frequency will increase by 2 cycles per degree and contrast will be reset. Preliminary data from this method in normally seeing and MD participants show both feasibility and tentative evidence that this training gives rise to improvements in acuity.
Study NCT05439759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Condition 2: Training spatial integration
Description: Spatial integration involves what the investigators refer to as mid-level vision. Spatial integration is a concern in developing a PRL since an area of the visual periphery that is best suited to discriminate a simple visual feature may not be appropriate to integrate information across objects, such as in reading or recognizing facial identity or expression. The investigators address this issue with a targeted spatial integration training approach developed by MPI Seitz and based on contour integration tasks used in previous PL studies to train mid-level visual processes. Target stimuli consist of contours formed by spaced Gabors. The difficulty is manipulated by varying orientation jitter of Gabors. Several optotypes will be included to promote generalization, including shapes and facial expressions.