AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06444646 — intervention group
Intervention type: OTHER
Intervention: Patient phenotyping
Description: Length and weight will be measured to calculate body mass index (BMI). Waist and hip circumference will be assessed, as well as blood pressure (both systolic and diastolic) and heart rate at rest. Body composition will be determined using a bioelectrical impedance analysis (BIA) in the hospital. Medication use and comorbidities (that are allowed within the in-/exclusion criteria) will also be derived from the patient's medical files with patient's permission.
Study NCT05752214 — intervention group
Intervention type: OTHER
Intervention: WEB Register
Description: Observational, non-profit, multicentre longitudinal study on the assessment of quality of life and its association with demographic variables and visual function of visually impaired patients attending the visual rehabilitation service.
Study NCT05902000 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Carotid Stenting
Description: Emergent carotid stenting will be performed if the patient is randomized in the intervention arm. The order to treat (head first or neck first) the extracranial carotid artery lesion will be left to the interventionist discretion.
Study NCT05902000 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Thrombectomy
Description: Intracranial thrombectomy is an endovascular procedure. In the experimental group, thrombectomy will be completed with extracranial carotid stenting.
Study NCT05902000 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dual antiplatelet treatment
Description: Dual antiplatelet therapy is administered after 24 hours of imaging follow-up excluding intracranial hemorrhagic complications. Aspirin Enteric-coated Tablets (Bay Aspirin) 100mg once a night+Clopidogrel Sulfate Tablets (Plavix) 75mg once daily. If there is no contraindication, maintain for more than 1 month, then adjust the dosing regimen according to the guidelines.
Study NCT05902000 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intraoperative Drug Treatment
Description: Tirofiban is used as an adjunct to endovascular therapy. The currently recommended dosing regimen is a combined intra-catheter arterial administration of a loading dose of 0.4 μg/(kg-min) for 30 min (total dose not to exceed 1 mg)， followed by intravenous pumping of 0.1μg/(kg-min) for 24-48h, and adjustment of dosing in conjunction with CT.
Study NCT05070377 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: 1. structured physical activity sessions by physical education (school), twice a week, with twenty-minute each lesson;~2. self-monitoring plus goal setting by pedometer (out-of-school), progressive goals to achieve weekly;~3. healthy lifestyle guidance ( parents social support).
Study NCT05481372 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Imaging
Description: Trans-perineal ultrasound and Magnetic resonance image acquisition
Study NCT05204043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Peter Hess® sound massage
Description: The Peter Hess® sound massage uses sound vibrations generated by therapeutic singing bowls. Peter Hess' methods act far from a traumatised area, far from the pain. It will be given on the patient's bed for 30 minutes.
Study NCT05204043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Music relaxation Music Care®
Description: The patient chooses his music preferences and receive the music relaxation in bed for 30 minutes.
Study NCT05204043 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaires
Description: * State Trait Anxiety Inventory (STAI)~* Pain assessment - Visual Analogic Scale (from 0 to 10).
Study NCT06251986 — intervention group
Intervention type: OTHER
Intervention: ofatumumab
Description: This is an observational study, there is no treatment allocation.
Study NCT06358274 — intervention group
Intervention type: OTHER
Intervention: Thru-hiking
Description: planning to embark on the Colorado Trail
Study NCT04972045 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CuminUP60®
Description: 4 capsules, 400 mg / capsule
Study NCT04972045 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Curcumin capsules
Description: 4 capsules, 400 mg / capsule
Study NCT05010460 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Roxadustat
Description: orally 100mg every other day for 5-8 days prior to CABG
Study NCT05010460 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: orally 100mg every other day for 5-8 days prior to CABG
Study NCT04825730 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JOINTSTEM
Description: JOINTSTEM is an OA treatment that uses autologous adipose-derived mesenchymal stem cells. As it does not use allogenic tissues and is incubated without additional genetic modification or mechanical and chemical modification through differentiation, it is classified as 'autologous cell therapy' and is completely free of immunologic rejection.
Study NCT05072613 — intervention group
Intervention type: OTHER
Intervention: Malaria screening
Description: Participants are screened for malaria and a dried blood spot is collected from malaria positive cases
Study NCT04848857 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Colchicine
Description: colchicine is a potent anti-inflammatory drug which is currently recommended for the treatment of pericarditis and acute gout attacks, but also familial Mediterranean fever and Behçet disease. This drug acts on inflammation through inhibition of microtubule polymerization by binding free tubule dimers. Colchicine blunts monocyte and neutrophil invasion at the site of inflammation and reduces intracellular trafficking and thus the release of cytokine and production of reactive oxygen species and a variety of proteolytic enzymes.
Study NCT04848857 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: the placebo is a drug with no chemical effects but with the same physical characteristics as the experiment drug colchine.
Study NCT05099367 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Microdialysis, current induced vasodilation
Description: CIV will be applied over all microdialysis fibers: one perfused with saline, one perfused with a preferential COX-1 blocker; and one perfused with a preferential COX-2 blocker.~CIV will be applied over all fibers in the following conditions: one perfused with saline, one perfused with fluconazole and L-NMMA, and the last one perfused with lidocaine.Dialysate collection will be performed after each CIV: dermal PGI2 metabolite (6-ketoPGF1α) and other COX-dependent prostanoids or metabolite (e.g. 11-dehydroTXB2) will be collected in the dialysate fluid and quantified. One hour after the last condition, treprostinil will be perfused over all fibers.
Study NCT05099367 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Skin biopsy
Description: Skin biopsy will be proposed. It will be performed on the internal superior calf (medial gastrocnemius), at a reasonable distance from the foot
Study NCT05099367 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: peri-ulcerated skin biopsy
Description: Non-ulcerated skin from the peri-wound area will be collected. These patient will not undergo all the procedures included in this protocol.
Study NCT05873166 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Bilateral pressure release in Flexor Brevis Digitorum in subjects with latent trigger point
Description: Bilateral pressure release in Flexor Brevis Digitorum in subjects with latent trigger point
Study NCT05873166 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Bilateral non emission Laser in latent trigger points of the Flexor digitorum Brevis Muscle
Description: Bilateral non emission Laser in latent trigger points of the Flexor digitorum Brevis Muscle
Study NCT04827667 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: bronchoalveolar lavage
Description: Bronchoalveolar lavage is performed by instillation and suction of saline in the middle lobe during bronchoscopy. Cytological examination and flow cytometry will be performed to assess PD-1lymphoctes.
Study NCT05006014 — intervention group
Intervention type: PROCEDURE
Intervention: Tooth guided immediate implant placement
Description: The technique of implant insertion consisted of a progressive preparation of the implant site using the anatomy of the root of the single rooted teeth to be extracted as a reference and as aid for apical engagement
Study NCT06025266 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Evaluation of Viscoelastic and mechanical properties with MyotonPRO
Description: MyotonPro™, a handheld, non-invasive and painless device, is used for non-invasive measurement of the biomechanical and viscoelastic properties of soft biological tissues such as superficial skeletal muscles, fascia, tendons and ligaments. The properties of the structures can be measured from different regions during complete rest or contraction.
Study NCT06531434 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Docetaxel, Cisplatin, fluorouracil, Radiation
Description: Induction chemotherapy with Docetaxel, Cisplatin, and fluorouracil for 4 to 8 cycles, followed by concurrent chemoradiotherapy with Cisplatin and Radiation 30.6-40 Gy.
Study NCT05352633 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intensive BP Arm
Description: Participants in the Intensive BP treatment group have a goal of SBP \<120 mmHg. It is recommended to provide long-acting antihypertensive medications, that is once daily, unless other medication delivery frequency is needed. The local investigator may select among the available study antihypertensive medications. Other drugs not supplied by the trial may also be used as the investigator determines appropriate. One or more medications from the following classes of agents will be provided by the study for use in managing participants in both randomization groups to achieve study goals: Angiotension converting enzyme (ACE)-inhibitors;Angiotension receptor blockers (ARBs); Thiazide-type diuretics; Loop diuretics; Potassium-sparing diuretics; Beta-blockers; Calcium channel blockers (CCBs); Direct vasodilators; Alpha1-receptor blockers; Sympatholytics
Study NCT05352633 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard BP Arm
Description: Participants in the Standard BP treatment group have a goal of SBP \<140 mmHg. The same medications used in the Intensive BP treatment group will be used for the Standard BP treatment group.
Study NCT04626401 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Forearm immobilization
Description: Two days of forearm immobilization
Study NCT04626401 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Forearm immobilization
Description: Two days of forearm immobilization
Study NCT05054452 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Echocardiographic assessment
Description: At baseline before standardized volume expansion, a first set of echocardiographic measurements will be performed. Then, we will perform 15-second end-expiratory and end-inspiratory occlusions. Occlusions will be separated by 1 minute to allow the cardiac index to return to its baseline value. A last set of measurements will be performed after fluid administration. Ventilatory settings and other treatments will remain unchanged during the study period.
Study NCT05867589 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 68Ga/18F-FAPI-04
Description: Subjects will receive one injection of 68Ga/18F-FAPI-04 (0.1\~0.15mCi/Kg), a PET radiopharmaceutical selective for fibroblast activation protein. 68Ga/18F-FAPI-04 injection will be followed by a 10 ml saline flush.
Study NCT06065085 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: mobile education
Description: The study was conducted as a randomized controlled trial with 134 individuals with hypertension (68 experimental, 66 controlled) who applied a university hospital. The data were collected by Patient Information Form, Healthy Lifestyle Behaviour Scale II, EQ-5D General Quality of Life Scale, Mindful Attention Awareness Scale and Percieved Stress Scale were used. An education application was installed on the mobile phones of the experimental group. Individuals with hypertension were provided with a training for three months through the mobile application. Data collection forms were filled in by the individuals with hypertension in the experimental and controlled groups at the beginning and at the 3rd month via the mobile application.
Study NCT06180187 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Electrical mallet
Description: elevation of the Schneiderian membrane of maxillary sinus using electrical mallet and place bone graft material to augment the residual alveolar ridge and then place dental implant .
Study NCT06180187 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Osseo-densification burs
Description: elevation of the Schneiderian membrane of maxillary sinus using osseodensification burs and place bone graft material to augment the residual alveolar ridge and then place dental implant .
Study NCT04696887 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tele Tai Chi Intervention for Persons Aging with Long-Term Mobility Disabilities
Description: • 8-week Tele Tai Chi intervention, participants will use a tablet or computer to join a small-group, online class (1hr, twice weekly) from home; during each session, participants will exercise as a group along with the pre-recorded video lessons and have the opportunity for social interaction (via video chat) before and after class.
Study NCT04950296 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group I: L. plantarum UALp-05TM,
Description: One capsule to be taken orally before lunch with a glass of water. In case the dose is missed, advise participant to take before dinner.
Study NCT04950296 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Group II: L. plantarum UALp-05TM,
Description: One capsule to be taken orally before lunch with a glass of water. In case the dose is missed, advise participant to take before dinner.
Study NCT04950296 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Microcrystalline cellulose
Description: One capsule to be taken orally before lunch with a glass of water. In case the dose is missed, advise participant to take before dinner.
Study NCT06269939 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: STEM
Description: Memory technique training
Study NCT06269939 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: STEM
Description: Memory technique training
Study NCT04728685 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Mechanical Traction
Description: Mechanical Traction will be applied to the lumbar region using a traction unit.
Study NCT04660643 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tirzepatide
Description: Administered SC
Study NCT04660643 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Administered SC
Study NCT06244238 — intervention group
Intervention type: OTHER
Intervention: Observational study
Description: Observational study
Study NCT04731935 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sparrow Therapy System
Description: Transcutaneous auricular neurostimulation
Study NCT04481997 — intervention group
Intervention type: OTHER
Intervention: Exposure to Anti-thrombotic treatment agents and glucose lowering therapy
Description: Exposure to Anti-thrombotic treatment agents and glucose lowering therapy
Study NCT04651387 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ozonized oil (HOO
Description: In addition to the routine standard treatments for COVID-19, in the intervention group, combined use of HOO capsules and HOO oropharyngeal and nasal spray will be administered 3 times per day (after breakfast, lunch, dinner, possibly with a delay of one hour from the routine treatment) and will be prescribed for 2 weeks (14 days).~Posology: 3 HOO capsules plus 3 HOO intranasal administrations for each naris plus 3 HOO oropharyngeal administrations.
Study NCT04704479 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Russian current
Description: For application of Russian current, 2 channels with 2 electrodes each will positioned on the oblique muscles and rectus abdominis motor points using wet spongy pads to enhance electrical activity. Russian current will be a carrier frequency 2500 Hz with frequency of 5 Hz for 5 minutes of muscular conditioning, 40 Hz for 10 minutes for training of slow contraction muscular fibers and 120 Hz for 5 minutes for training of fast contraction muscular fibers with On time (contraction time) 4 secs and Off time (relaxation time) 2 secs. The contraction phase will be at time of patient's expiration while relaxation will be at time of patient's inspiration
Study NCT04704479 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EMT
Description: patients in both groups trained 3 times a week, each session consisting of 1/2 h by the end of sessions. Initially, repeated cycles of 3 min of work followed by 2 min of rest were conducted (total work- time 18 min). The length of work intervals was increased on a weekly basis while rest periods were shortened to obtain a total work time of 30 min in the last week of the program. The valve opening pressure was continuously monitored at the mouthpiece to ensure the achievement of the target pressure. Patients will receive EMT with a threshold expiratory muscle trainer (Threshold; HealthScan), started breathing through the expiratory port of the threshold muscle trainer at a resistance equal to 15% of their Pemax for 1 week. The resistance will then increase incrementally, 5 to 10% each session, to reach 60% of their baseline Pemax at the end of the first month then continued at 60% of the Pemax, will be adjusted weekly to the new Pemax achieved
Study NCT04704479 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EMT
Description: patients in both groups trained 3 times a week, each session consisting of 1/2 h by the end of sessions. Initially, repeated cycles of 3 min of work followed by 2 min of rest were conducted (total work- time 18 min). The length of work intervals was increased on a weekly basis while rest periods were shortened to obtain a total work time of 30 min in the last week of the program. The valve opening pressure was continuously monitored at the mouthpiece to ensure the achievement of the target pressure. Patients will receive EMT with a threshold expiratory muscle trainer (Threshold; HealthScan), started breathing through the expiratory port of the threshold muscle trainer at a resistance equal to 15% of their Pemax for 1 week. The resistance will then increase incrementally, 5 to 10% each session, to reach 60% of their baseline Pemax at the end of the first month then continued at 60% of the Pemax, will be adjusted weekly to the new Pemax achieved
Study NCT04789356 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Adsorbed SARS-CoV-2 (inactivated) vaccine
Description: 600 SU/dose; Two doses separated by 28 days (± 7 days). Intramuscular (deltoid) administration.
Study NCT05984069 — intervention group
Intervention type: OTHER
Intervention: observational prospective data collection
Description: Collection of data from medical records.
Study NCT04813029 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Straight leg raise maneuver
Description: With the patient in supine position, one leg is raised to form an angle of at least 45 degrees with the bed. The patient will be asked to keep that position for at least 5 seconds. The maneuver will be repeated after 20-30 seconds. The first adequate maneuver will be considered for the study. Intra-esophageal and intra-abdominal pressure will be analyzed both during baseline and SLR maneuver. Intra-esophageal pressure is measured as peak and mean over 5 seconds, 1 cm and 5 cm above the proximal margin of the LES. Intra-abdominal pressure will be measured as peak and mean over 5 seconds 1 cm below the distal margin of the diaphragm notch.
Study NCT05253261 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Preoperative Cone Beam Computed Tomography (CBCT) scan
Description: CBCT scans (Green X, Vatech, Hwaseong, Korea) are carried out prior to cystostomies. The scanning conditions are constant at 200 µm isotropic voxel size with 360° rotation, 94 kV tube voltage, 7.2 mA tube current and 9 s exposure time with a 15 × 8 cm field of view field of view (FOV).
Study NCT05253261 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: tooth removal and cystostomy
Description: Surgical interventions are carried out in local anaesthesia. If it is deemed that a tooth or teeth included in the odontogenic cyst is of hopeless prognosis, it is removed at the time of cystostomy procedure. During cystostomy a bony window is created to accessthe cyst. The lining of the cyst is opened to accomodate the tube of the decompression appliance. A sample from the lining of the cyst is sent for histologic evaluation to confirm the diagnosis of odontogenic cyst.
Study NCT05253261 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Decompression
Description: The decompression appliances is delivered in the same sitting as the cystostomy. Patients are instructed on how to wear and clean their decompression device and are recalled for clinical examinations.
Study NCT05253261 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Postoperative Cone Beam Computed Tomography (CBCT) scan
Description: Postoperative CBCT examination is performed six months into the decompression period using the same scanning conditions as those used for the preoperative CBCT scan.
Study NCT05253261 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cyst Enucleation
Description: Following the decompression period enucleation of the remaining cyst is carried out in local anaesthesia.
Study NCT06399497 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: spinal manipulation
Description: A high-velocity low-amplitude spinal manipulation at the L5 level will be performance by means of the lumbar roll technique, with the subject in right lateral decubitus.