AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05345067 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-3
Description: Section 3: Childish games (10 minutes): Childish games are used that will help to laugh for no reason, just like a child. Imagining these games and plays, the arms are raised upwards in the form of a Y with palms facing the sky, motivating the group by saying very good (clap), very good (clap), yes. The leader of laughter yoga speaks out very good (clap), very good (clap), hey (arms to the right and left) to keep the group's energy high and generate enthusiasm in the deep breathing exercises and laughter exercises sections. According to the energy and desire of the group, this section is completed after about 10 minutes.
Study NCT05345067 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Experimental: Laughter yoga session parts-4
Description: Section 4: Laughter exercises (15 minutes): This section contains a variety of laughter exercises that will laugh, such as greetings, laughter cream, exploding balloon laughter, preparing and drinking strawberry milk, bonuses, hot soup, lion, aloha, bird, appreciation, elevator, and cream pie. A laugh is raised by doing only laughter exercises for no reason at all. At the end of this section, relaxation is achieved for about three minutes using deep breathing exercises. The group is given verbal guidance Put your hand on your heart, feel your heartbeat, let's exhale with a smile, make a wish or pray, smile as if we had achieved our wish, and the laughter yoga session is terminated.
Study NCT05357989 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: buntanetap/posiphen
Description: HPMC (vegetarian source) capsule shells
Study NCT05357989 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: HPMC (vegetarian source) capsule shells
Study NCT05950061 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sertraline
Description: Sertraline (200 mg/day) capsule
Study NCT05950061 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Escitalopram
Description: Escitalopram (10 mg/day) capsule
Study NCT05676151 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music Therapy
Description: 20-minute music-therapy-informed interventions (musical bingo, songwriting, lyric scramble) guided by a music therapist
Study NCT04695054 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Buzzy device plus EMLA cream
Description: EMLA cream will be applied 60 minutes before the needle procedure; the Buzzy device will be used during the procedure
Study NCT04695054 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Only EMLA cream
Description: EMLA cream will be applied 60 minutes before the needle procedure
Study NCT05577936 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: XPERIENCE Advanced Surgical Irrigation
Description: A clear, colorless, aqueous solution that is indicated for use in the cleansing and removal of debris, including microorganisms, from wounds. Soak for 3 minutes for a total volume of 1L
Study NCT05577936 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care Irrigation
Description: 17.5 mL povidone-iodine with 500 mL normal saline: solution (0.35%) for 3 minutes for a total volume of 1L (including a normal saline rinse)
Study NCT05811273 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical readiness training
Description: Bend and Reach:5 repetitions, Rear Lunge:5 repetitions per leg, High Jumper:5 repetitions, Rower:5 repetitions, Squat Bender:5 repetitions, Windmill:5 repetitions, Forward Lunge:5 repetitions per leg, Prone Row:5 repetitions, Bent-Leg Body Twist:5 repetitions per side, Push-Up:5 repetitions.
Study NCT05811273 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control group
Description: general exercises
Study NCT05590559 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine
Description: Opiates
Study NCT05590559 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided erector spinae plane block
Description: PVB
Study NCT05758584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intervention
Description: Vibrating tourniquet
Study NCT05758584 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Distraction card
Description: Distraction card
Study NCT04809376 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium twice weekly
Description: Subcutaneous Injection, 1.5mg/kg Ideal body Weight (IBW)
Study NCT04809376 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (Sodium Chloride Injection, 0.9%)
Description: Placebo to match PPS
Study NCT04809376 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Sodium Chloride Injection, 0.9%)
Description: Placebo to match PPS
Study NCT04809376 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium Fixed Dose
Description: Subcutaneous Injection, 100/150/180 mg if \<65kg/ ≥ 65 kg and ≤ 90kg/ >90 kg IBW
Study NCT04809376 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentosan Polysulfate Sodium once weekly
Description: Subcutaneous Injection, 2.0mg/kg Ideal body Weight (IBW)
Study NCT05001126 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 1x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 1x/week represents a dose of one HIFT workout per week.
Study NCT05001126 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 2x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 2x/week represents a dose of two HIFT workouts per week.
Study NCT05001126 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HIFT 3x/week
Description: HIFT is a time-efficient modality of exercise combining high-intensity aerobic and resistance training using minimal equipment. HIFT 3x/week represents a dose of three HIFT workouts per week.
Study NCT04603300 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: INT301
Description: INT301 is an allergy immunotherapy delivered in the form of a fully functional toothpaste
Study NCT04603300 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Fully functional toothpaste containing no immunotherapy agents
Study NCT04309188 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Senaptec Strobe Glasses
Description: The glasses use liquid crystal technology that causes a flicker from clear to opaque to enhance vision.
Study NCT04309188 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard softball drills
Description: Control group, which will perform normal hitting and fielding drills without stroboscopic training
Study NCT04950920 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Y-2 sublingual tablets
Description: 30mg Edaravone+6mg d-borneo OR， Bid
Study NCT04950920 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: d-borneol
Description: 60 μg d-borneol OR， Bid
Study NCT05062343 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dilapan-S
Description: Osmotic dilator
Study NCT05062343 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Cook Cervical Ripening Balloon
Description: Double balloon catheter for cervical ripening
Study NCT06399978 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brain Blossom - Gamified Differential Outcome Training
Description: Digital cognitive training with a gamified DOT task for 20 minutes per day 3-4 times a week for 6-8 weeks.
Study NCT06399978 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Gamified Non-Differential Outcome Training
Description: Digital cognitive training with a gamified NDOT task for 20 minutes per day 3-4 times a week for 6-8 weeks.
Study NCT05991076 — intervention group
Intervention type: OTHER
Intervention: Latin Dance
Description: The Activate Bailando class is a dance-focused exercise class that is offered once per week for one hour. The program has been developed by dance educators in the Madison area.
Study NCT06362811 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Sacral Erector Spinae Plane Block
Description: Ultrasound-guided bilateral injection of 1ml/kg 0.25% bupivacaine into the plane underneath the erector spinae muscles over sacral crests. The needle is inserted with in-plane technique from cranial to caudal direction over S3-4.
Study NCT05773287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Targeted Health Coaching Group
Description: Participants in the THC group will receive an exercise prescription (steps/day) based on their last cardiac rehabilitation session exercise prescription. Participants will be provided a Garmin wearable device to track steps/day. Additionally, participants will partake in 6 virtual or in-person health coaching sessions lasting approximately 30-60 minutes in duration. These sessions will take place approximately every other week during the 3-month intervention period.
Study NCT05773287 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Standard Care Group
Description: Participants in the SC group will receive an exercise prescription (steps/day) based on their last cardiac rehabilitation session exercise prescription. Participants will be provided a Garmin wearable device to track steps/day. Additionally, participants will be provided with a single virtual or in-person education session, lasting approximately 30 minutes, at the beginning of the 3-month intervention period.
Study NCT06437860 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MIND Diet
Description: Daily meals designed to increase adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) dietary pattern.
Study NCT06437860 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Control Diet
Description: Daily meals designed to increase fruit, vegetable, and whole grain intake consistent with a healthy American diet.
Study NCT05693441 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Active berry product
Description: Subjects should consume the active product containing nordic berries daily during the 12 week intervention period.
Study NCT05693441 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Reference berry-like product
Description: Subjects should consume a reference product (isocaloric to active product, containing berry aromas and colouring but no actual berry compounds) daily during the 12 week intervention period.
Study NCT06501482 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Postoperative reintroduction of FOLFIRI based chemotherapy
Description: Postoperative reintroduction of FOLFIRI: irinotecan 180 mg/m2 + leucovorin 400 mg/m2 at day 1 then 5-FU 400 mg/m2 bolus followed by 2400 mg/m2 continuous infusion over 46 h biweekly. For a total of 12 cycles of perioperative chemotherapy including the preoperative chemotherapy
Study NCT03810898 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radioligand [¹¹C]CHDI-00485180-R
Description: Intravenous injection of radioligand in the arm with PET imaging of the brain.
Study NCT03810898 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radioligand [¹¹C]CHDI-00485626
Description: Intravenous injection of radioligand in the arm with PET imaging of the brain.
Study NCT06286904 — intervention group
Intervention type: DEVICE
Intervention: Skiin Garment system
Description: Individuals will be asked to wear a Skiin Garment system for the duration of their hospitalization (minimum one day).The system will collect accelerometer, ECG, temperature, heart rate, steps and sleep metrics data if enable. Then, they will be asked to answer a questionnaire about their experiences with the device and the study.
Study NCT04219319 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Efficacy of LCAR-T2C CAR-T cells
Description: CD4-directed CAR-T cells administered with lymphodepletion, and to obtain the preliminary efficacy results in subjects who have been diagnosed with relapsed or refractory CD4 positive T lymphocyte tumor
Study NCT06234007 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib, Adebrelimab, Oxaliplatin, Capecitabine
Description: Safety run-in phase: Fruquintinib 4mg/d, oral, once daily, continuous treatment for 2 weeks, 1 week off, q3w, 6 cycles; If the number of patients experiencing dose-limiting toxicity (DLT) was ≤1, the study would continue at that dose level. If the number of patients with DLTs was >1, the dose of fruquintinib was decreased to 3mg/d, qd po, d1-14, q3w, and the dose expansion phase was continued；Adebrelimab 1200mg, d1, IV infusion, q3W, 6 cycles; Capecitabine 1000 mg/m2, twice a day, po, d1-14, followed by 7 days of rest, q3W, 6 cycles; Oxaliplatin 130 mg/m2, d1, q3W, 6 cycles;~Dose expansion phase: Fruquintinib RP2D, qd po, d1-14, q3w, 6 cycles; Adebrelimab 1200mg, d1, IV infusion, q3W, 6 cycles; Capecitabine 1000 mg/m2, twice a day, po, d1-14, followed by 7 days of rest, q3W, 6 cycles; Oxaliplatin 130 mg/m2, d1, q3W, 6 cycles;
Study NCT04406818 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Carbon Dioxide
Description: Participants inhale carbon dioxide while in magnetic resonance imaging scan to measure cerebrovascular reactivity
Study NCT04873232 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Engensis
Description: Injections with Engensis in study VMDN-003-2
Study NCT04873232 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Injections with Placebo in study VMDN-003-2
Study NCT04657211 — intervention group
Intervention type: OTHER
Intervention: prospective observational cohort study
Description: prospective observational cohort study
Study NCT05571098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: individualized colorectal cancer education
Description: Subjects taught within the scope of individualized colorectal cancer education:~* Common symptoms and management related to disease and treatment,~* Importance of nutrition in the treatment process.
Study NCT05571098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: psycho-oncological counseling
Description: Topics discussed within the scope of psycho-oncological counseling:~* Psychological state (anxiety, depression, etc.),~* Coping strategies about the process,~* Presence of fear about the disease and/or treatment,~* Lifestyle changes/problems,~* Changes in body image,~* Family/friendship/work-related concerns,~* Additional issues, comments he wishes to convey
Study NCT05571098 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: telephone support hotline service
Description: Within the scope of the NNP, a telephone support hotline service was provided to the participants, where they could consult at any time about the subject they wanted.
Study NCT06118541 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Vestibular Rehabilitation therapy
Description: Vestibular rehabilitation exercises of 30 to 60 minutes twice a week for eight weeks~Vestibular rehabilitation exercise program:~1. Eye-Head Coordination exercise~2. Sitting balance exercises~3. Standing Static balance exercises~4. Standing Dynamic balance exercises~5. Ambulation exercises
Study NCT05718752 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Maximal incremental exercise test
Description: Gas exchange are measured during all the test on ergocycle until oxygen consumption reach its maximum value
Study NCT05718752 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 30-min submaximal exercise test
Description: A 30-min submaximal test on ergocycle. Gas exchange are measured during all the test. Blood samples are collected before, at the end of exercise and after 3 hours of recovery
Study NCT05353712 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SUCROSE
Description: 50g sweet creme composed of 14.3g vegetable fat and 35.7g sucrose.
Study NCT06335914 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Ga 68 PSMA-11 PET
Description: Positron emission tomography (PET) imaging using Ga68 PSMA 11 radiotracer
Study NCT06335914 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: 18F-DCFPyL PET
Description: Positron emission tomography (PET) imaging using 18F-DCFPyL radiotracer.
Study NCT06335914 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: FDG PET
Description: Positron emission tomography (PET) imaging using (18) F-fluorodeoxyglucose radiotracer.
Study NCT06494839 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Bipolar electrocautery tonsillectomy technique
Description: The BED tonsillectomy procedures were done under general anesthesia, and the patient's position was the same as in the other method. The bipolar machine was adjusted to 30 watts, and a mucosal incision was cauterized with a single straight or stepped bipolar forceps. After carefully cauterizing the tissue, the palatine tonsil was located and removed from the superior to the inferior pole. Most of the identifiable vessels supplying the tonsil were cauterized before being separated from the tonsil. Point coagulation was used to maintain hemostasis. By using point coagulation, hemostasis was maintained. To avoid bias stemming from competence, consultants performed all of these tonsillectomies.
Study NCT06494839 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Cold steel dissection technique
Description: The cold steel blunt dissection tonsillectomy was carried out under general anesthesia while the patient was in the Rose position and had an endotracheal intubation. The tonsil was retracted medially with a tonsil holding forceps, and in the upper pole, the mucosal incision was made. To protect the tonsillar pillars, a delicate dissection was performed, and the suction tip was used to stop the hemorrhage. The tonsillar fossa was packed with swabs. The other palatine tonsil was then similarly removed. Hemostasis was secured by silk ligation and bipolar electrocautery.
Study NCT04208984 — intervention group
Intervention type: DEVICE
Intervention: Study
Description: After consent and assent the child and parent will be introduced the Lullabreath in pre-op. The purpose of Lullabreath will be explained and the Lullabreath will be taught (15 minutes). The parent will complete the PROMIS Proxy Anxiety short form. The children are then taken to the operating room (leave parents) with the Lullabreath. The anesthesiologist will hook the device up to the anesthesia circuit and start the Lullabreath. The child will then undergo induction of anesthesia while playing the Lullabreath.
Study NCT04208984 — intervention group
Intervention type: OTHER
Intervention: Music Video
Description: After consent and assent the child and parent will be introduced to the game in pre-op. The purpose of the game will be explained and the game will be taught (15 minutes). The parent will complete the PROMIS Proxy Anxiety short form. The children are then taken to the operating room (leave parents) with the game. The anesthesiologist will hook the device up to the anesthesia circuit and start the game. The child will then undergo induction of anesthesia while playing the game. The child can choose to watch one of two music videos (Frozen, Lion King)
Study NCT05255406 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Furmonertinib (160mg)
Description: 160mg/day orally on a continuous dosing schedule. If subjects suffer from AEs, they can get declined dosage (80mg).
Study NCT05647265 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Given IV
Study NCT04894903 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diabetes Care Gaps Patient Portal Intervention
Description: The Diabetes Care Gaps Patient Portal Intervention is embedded within an existing patient web portal (My Health at Vanderbilt). The intervention (a) notifies patients when selected, clinically meaningful, evidence-based diabetes monitoring \& preventative care (e.g., annual urine microalbumin) are due and (b) allows patients to initiate orders for the care.
Study NCT03649464 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OKN-007
Description: Dose escalation/PK cohort (Phase Ib): 1000mg twice daily (BID), 1000mg thrice daily (TID), 1500mg thrice daily (TID).~Expansion cohort (Phase 2): MTD defined in the dose escalation (Phase Ib) study.
Study NCT05850572 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fecal microbiota transplantation(FMT)
Description: Subjects will receive FMT capsules (10\^12 CFU/capsule) in addition to their usual antidepressant treatment. Subjects will continue to receive FMT capsules for 8 weeks. New SSRI antidepressants (fluoxetine, citalopram, escitalopram, sertraline, paroxetine, and fluvoxamine) recommended by current treatment guidelines can be used during this period, and the effective therapeutic dose of the drugs can be added within 1 week.
Study NCT05850572 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will receive a placebo capsule with the same color, appearance, and smell as the FMT capsule, in addition to their usual antidepressant treatment. Placebo capsules contained the food probiotic Lactobacillus (10\^12 CFU per capsule). Subjects will continue to receive placebo capsules for 8 weeks. New SSRI antidepressants (fluoxetine, citalopram, escitalopram, sertraline, paroxetine, and fluvoxamine) recommended by current treatment guidelines can be used during this period, and the effective therapeutic dose of the drugs can be added within 1 week.
Study NCT06509646 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tia Chi Exercise
Description: • Yang style 24-posture short-form (16) for 30 minute It consists of 24 unique movements that are performed in a sequence. The form is designed to be easy to learn and can be completed in about six minutes.~Treatment dosage will be 1 session per day of 1 hour class, 2 sets per session, and 5 repetitions per set, 3 times per week and for 12 weeks