AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05977127 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Comirnaty
Description: Administration of Comirnaty vaccine
Study NCT06241196 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Vestibular Socket Therapy
Description: tunnel incision will be made in labial vestibule
Study NCT05686161 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: SW-BIC-213;SARS-Cov-2.
Description: The study will be performed in people receiving two doses of Sinopharm vaccine over 180 days (± 30 days) after the second dose prior to enrollment. The three study groups who will receive the booster dose will be assigned as follows:~Subjects (N≈600) Group 1: (N≈200) - Stemirna(SW-BIC-213) Group 2: (N≈200) - Pfizer(BNT162b2) Group 3: (N≈200) -Sinopharm (BIBP) Study groups: There will be three study groups. Study Group Assignment: Randomization (1:1:1) will be applied for subjects to account for the different number of doses per vial for different vaccines and short shelf life.
Study NCT05686161 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Sinopharm (BIBP);SARS-Cov-2.
Description: The study will be performed in people receiving two doses of Sinopharm vaccine over 180 days (± 30 days) after the second dose prior to enrollment. The three study groups who will receive the booster dose will be assigned as follows:~Subjects (N≈600) Group 1: (N≈200) - Stemirna(SW-BIC-213) Group 2: (N≈200) - Pfizer(BNT162b2) Group 3: (N≈200) -Sinopharm (BIBP) Study groups: There will be three study groups. Study Group Assignment: Randomization (1:1:1) will be applied for subjects to account for the different number of doses per vial for different vaccines and short shelf life.
Study NCT05686161 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Pfizer(BNT162b2);SARS-Cov-2.
Description: The study will be performed in people receiving two doses of Sinopharm vaccine over 180 days (± 30 days) after the second dose prior to enrollment. The three study groups who will receive the booster dose will be assigned as follows:~Subjects (N≈600) Group 1: (N≈200) - Stemirna(SW-BIC-213) Group 2: (N≈200) - Pfizer(BNT162b2) Group 3: (N≈200) -Sinopharm (BIBP) Study groups: There will be three study groups. Study Group Assignment: Randomization (1:1:1) will be applied for subjects to account for the different number of doses per vial for different vaccines and short shelf life.
Study NCT06241196 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Alloderm
Description: allogenic soft tissue substitute
Study NCT06241196 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Xenogenic bone membrane shield
Description: xenogenic bone membrane
Study NCT06241196 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Xenogenic bone membrane shield
Description: xenogenic bone membrane
Study NCT06241196 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Connective tissue graft
Description: soft tissue harvesting from palate
Study NCT06274580 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: embolization of the middle meningeal artery
Description: Embolization of the MMA is occluded with PVA particles or liquid embolizing materials
Study NCT06428838 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Eptinezumab
Description: The study treatment consists of a single infusion of eptinezumab (100mg/mL).
Study NCT06428838 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard of Care
Description: SoC may include a combination of Toradol, Metoclopramide, and/or Benadryl. Ketamine and/or Midazolam may also be used, according to a stepwise approach, at the discretion of the treating physician. The timing and dose of all medication(s) administered in the ED will be recorded.
Study NCT06428838 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard of Care
Description: SoC may include a combination of Toradol, Metoclopramide, and/or Benadryl. Ketamine and/or Midazolam may also be used, according to a stepwise approach, at the discretion of the treating physician. The timing and dose of all medication(s) administered in the ED will be recorded.
Study NCT04824248 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Pain Neuroscience Education
Description: Increase pain coping skills and educating the patients that pain is in the brain, and that hypersensitivity of the central nervous system rather than local tissue damage contributes to their symptoms.
Study NCT04824248 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Pain Neuroscience Education
Description: Increase pain coping skills and educating the patients that pain is in the brain, and that hypersensitivity of the central nervous system rather than local tissue damage contributes to their symptoms.
Study NCT04824248 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Cognition-targeted exercise therapy
Description: Daily (physical) activity and exercise therapy. To confront the patient with movements and activities that are feared, avoided and/or painful using a gradual and cognition-targeted approach.
Study NCT04824248 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognition-targeted exercise therapy
Description: Daily (physical) activity and exercise therapy. To confront the patient with movements and activities that are feared, avoided and/or painful using a gradual and cognition-targeted approach.
Study NCT04824248 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral weight reduction program
Description: Changes in diet, behavior and a physical exercise to reach weight loss. It will include a lifestyle approach, incorporating behavioral theories and constructs to assist and facilitate healthy energy balance related behavior.
Study NCT05806567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Belumosudil
Description: Pharmaceutical form: Tablet; Route of administration: Oral
Study NCT05806567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: UGT1A1 victim drug
Description: Pharmaceutical form: Tablet; Route of administration: Oral
Study NCT05806567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: P-gp victim drug
Description: Pharmaceutical form: Capsule; Route of administration: Oral
Study NCT05806567 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: OATP1B1/BCRP victim drug
Description: Pharmaceutical form: Tablet; Route of administration: Oral
Study NCT05051605 — intervention group
Intervention type: BIOLOGICAL
Intervention: COVID-19 Vaccine
Description: Severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2)vaccine according to vaccine availability in the Egyptian ministry of health.
Study NCT04973059 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SmartDrive Summer
Description: The SmartDrive is a power assist accessory for a manual wheelchair
Study NCT04973059 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: SmartDrive Winter
Description: The SmartDrive is a power assist accessory for a manual wheelchair
Study NCT05490602 — intervention group
Intervention type: PROCEDURE
Intervention: Running subcutaneous sutures technique
Description: The Running subcutaneous sutures consist of running sutures in the profound and superficial dermis without knotting the thread (suture).
Study NCT05490602 — intervention group
Intervention type: PROCEDURE
Intervention: Classical closures
Description: Classical closures
Study NCT01596153 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Go Live
Description: Enhanced Probiotic, one packet bid until 7 days after discontinuation of antibiotic
Study NCT01596153 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Go Live
Description: Enhanced Probiotic, one packet bid until 7 days after discontinuation of antibiotic
Study NCT04995653 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Pre-Treatment
Description: Four times daily dosing with Vancomycin
Study NCT04995653 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vancomycin Placebo
Description: Four times daily dosing with Vancomycin Placebo
Study NCT04995653 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SER-155
Description: Once daily dosing with SER-155
Study NCT04995653 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: SER-155 Placebo
Description: Once daily dosing with SER-155 placebo
Study NCT04891211 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D deficiency
Description: Ocular significance of vitamin D deficiency in pediatric cases
Study NCT05073328 — intervention group
Intervention type: OTHER
Intervention: COVID-19 required hospitalisation
Description: Patients who contracted a COVID19 required hospitalisation
Study NCT06660745 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: telenursing-based family empowerment program
Description: The intervention was conducted in two sections. The first part included a one-day educational workshop conducted through Skype for the child and their caregiver and was planned to introduce the members of the intervention group to each other and provide information on how to deliver and receive the content. In the second part of the intervention, the content was prepared based on a scheduled plan. It was in the form of a 5-10-minute audio file, video, or educational text and was uploaded on the SendBig website. Once the upload is complete, a link is provided to the user. The link was sent to the phone numbers of children with cystic fibrosis and their caregivers so that they could watch the weekly content over three months. Once it was confirmed that the link had been received (acknowledged in the Cystic Fibrosis Companions group) and the content had been viewed, remote follow-ups were scheduled twice a week, on Sundays and Tuesdays between 6:00 PM and 8:00 PM, using Skype messenger.
Study NCT06602349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine 10 MG/ML
Description: administration of lidocaine in posterior perineal block infiltration
Study NCT06602349 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Description: administration of salin solution in posterior perineal block infiltration
Study NCT06617728 — intervention group
Intervention type: PROCEDURE
Intervention: Intervention 1: Regional Analgesia
Description: Regional analgesia techniques like epidural or peripheral nerve blocks.
Study NCT06617728 — intervention group
Intervention type: DRUG
Intervention: Intervention 2: Intravenous (IV) Analgesia
Description: IV medications used for pain control, including opioids and non-opioid analgesics.
Study NCT06016569 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Exhaled breath condensate sampling
Description: Patient will breath for approx. 10 minutes to a breath condenser. The exhaled breath sample will be condensed and freezed.
Study NCT06016569 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Blood sampling
Description: A venous blood sample will be taken for further biomarker analysis.
Study NCT06016569 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: LDCT
Description: LDCT scan will be performed.
Study NCT05348343 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Autologous platelet-rich plasma
Description: PRP created using a commercially available system will be used for treatment. PEFA-PRP will be created by subjecting PRP to a pulsed electrical field in a specially designed instrument developed by sponsor. Two 9 cm2 contralateral regions of interest (ROI) on the scalp will be treated with approximately 6mL of either PRP or PEFA-PRP by subcutaneous injection.
Study NCT05048368 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Larotinib
Description: Capsules, Oral, 350 mg, single dose, one day
Study NCT06529549 — intervention group
Intervention type: OTHER
Intervention: Organoid-Based Drug Sensitivity Screening
Description: Residual tissue of bone metastatic sites from biopsies for genetic testing will be collected to culture organoid and perform drug sensitivity screening
Study NCT06016569 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Vital signs
Description: Blood pressure, weight, height, pulse, oxygen saturation will be measured.
Study NCT06016569 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Spirometry
Description: Spirometry will be performed.
Study NCT06620445 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interventiion or CBT Group
Description: This RCT aims to evaluate the effect of Cognitive Behavioral Therapy (CBT) compared to usual care (UC) in pediatric oncology patients. We hypothesize that those receiving CBT will report lower depression and anxiety and improved QoL six months post-enrollment.
Study NCT06622122 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Intervention for Emotional Distress(MIED)-normal version
Description: Mindfulness Intervention for Emotional Distress (MIED) program provides standard audio instructions for mindfulness exercises, introduces the nature and law of anxiety, depression, and other emotions, the source of anxiety, depression, and other emotional distress, and the strategies and methods to alleviate emotional distress. These exercises, knowledge and strategies are based on the latest progress in the field of psychological counseling and treatment, and their application in daily life can help alleviate anxiety, depression and other emotional problems.
Study NCT06622122 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Intervention for Emotional Distress(MIED)-increase cognitive flexibility
Description: Increase the intervention dose of cognitive flexibility in Mindfulness Intervention for Emotional Distress (MIED). For example, including more cognitive reappraisal practice, psychoeducational content and practice about regarding thoughts just as thoughts.
Study NCT06618625 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: nasotracheal intubation
Description: For nasotracheal intubation, the nasal RAE tube will be inserted with it rotated by 90 degrees in counter-clockwise direction for patients in the 'Rotation' arm.~For nasotracheal intubation, the nasal RAE tube will be inserted without tube rotation for patients in the 'Neutral' arm.
Study NCT06618625 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: nasotracheal intubation
Description: For nasotracheal intubation, the nasal RAE tube will be inserted with it rotated by 90 degrees in counter-clockwise direction for patients in the 'Rotation' arm.~For nasotracheal intubation, the nasal RAE tube will be inserted without tube rotation for patients in the 'Neutral' arm.
Study NCT06618248 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: Sirolimus coated balloon angioplasty
Description: This study involves the use of a Sirolimus-Coated Balloon (SCB) for the treatment of coronary artery disease, specifically targeting coronary bifurcation lesions. The SCB is coated with sirolimus, an antiproliferative drug that helps to prevent restenosis by inhibiting smooth muscle cell proliferation. The balloon is inflated at the target lesion site, delivering the drug directly to the arterial wall. This intervention aims to achieve vessel dilation while reducing the risk of restenosis, providing a potential alternative to stent placement.
Study NCT06618248 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel coated balloon angioplasty
Description: This study involves the use of a Paclitaxel-Coated Balloon (PCB) for the treatment of coronary artery disease, specifically targeting coronary bifurcation lesions. The PCB is coated with paclitaxel, an antiproliferative drug that helps to prevent restenosis by inhibiting smooth muscle cell proliferation. The balloon is inflated at the target lesion site, delivering the drug directly to the arterial wall. This intervention aims to achieve vessel dilation while reducing the risk of restenosis, providing a potential alternative to stent placement.
Study NCT06620978 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Low pressure: Operative hysteroscopy without anesthesia with normal Saline medium in low pressure..
Description: Low pressure: Operative hysteroscopy without anesthesia with normal Saline medium in low pressure..~Operative hysteroscopy without anesthesia using normal Saline as medium with different pressure according to the arm allocated. The procedure is done for endometrial polyp removal, retained products of conception removal, intrauterine adhesyolisis and intrauterine device removal.
Study NCT06620978 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: High pressure: Operative hysteroscopy without anesthesia with normal Saline medium in High pressure.
Description: High pressure: Operative hysteroscopy without anesthesia with normal Saline medium at high pressure.
Study NCT06621797 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Intervention 1: Dietary Supplement - Caffeine Supplement
Description: Participants in this group will receive a caffeine supplement (3 mg/kg body weight) taken orally 45 minutes before performance testing. No additional interventions will be administered.
Study NCT06621797 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Intervention 2: Dietary Supplement - Caffeine + L-Theanine Supplement
Description: Participants in this group will receive a caffeine supplement (3 mg/kg body weight) along with L-theanine in a 1:2 ratio taken orally 45 minutes before performance testing.
Study NCT06621797 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention 3: Dietary Supplement - Caffeine Supplement + Diaphragmatic Breathing Exercises
Description: Participants in this group will receive a caffeine supplement (3 mg/kg body weight) 45 minutes before performance testing, followed by a 10-minute session of diaphragmatic breathing exercises.
Study NCT06620900 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated Model of Care
Description: The Integrated Model of Care was developed and piloted by the study team provide support for individuals seeking care in an interdisciplinary intensive outpatient program for mild traumatic brain injury to receive support for co-occurring substance use-related needs.
Study NCT06619340 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Exparel
Description: 20 milliliter (mL) EXPAREL with 20mL bupivacaine hydrochloride (HCL) 0.5% will be expanded. An 18-gauge bevel needle will be introduced through the capsular pocket at 1 to 2cm proximal to the adductor tubercle at the proximal border of the posteromedial femoral condyle. The needle will be angled proximally and posteriorly, and then advanced to contact the posteromedial capsule. A 20mL bolus of the study drug admixture will be administered. The remaining 20mL of the study drug admixture will be administered to the anterior and lateral knee structures with approximately 1 to 1.5mL administered with each stick to the intended area.
Study NCT06618261 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Caffeine + Resistance exercise
Description: Acute caffeine intake (3 mg/kg) prior each resistance training session of a 8 weeks training program.
Study NCT06618261 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo + Resistance exercise
Description: Acute placeb intake (3 mg/kg of maltodextrin) prior each resistance training session of a 8 weeks training program.
Study NCT06623838 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Evolutionarily informed case conceptualization
Description: Case conceptualization of personality functioning of a few transcripts of initial sessions and report of psychometric measures of patients diagnosed with personality disorder.
Study NCT06622200 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-based Intervention
Description: In the present research, the standardized, theory based MBI was introduced to the experimental group (Smith, 2005). This 30-minute protocol involves a series of activities, including paying attention to and being aware of breath, body sensations, thoughts, and sounds without judgment. This protocol is a widely recognized and utilized method due to its simplicity and accessibility, making it an ideal choice for this study.~Participants in the experimental group completed three weekly sessions of MBI for five weeks during their hemodialysis treatments (Alhawatmeh et al., 2022). Participants were provided with audio recordings of the MBI protocol, which they could practice during hemodialysis sessions. These recordings were delivered via email and WhatsApp, depending on their preference. This audio recording was developed based on the Smith's protocol by a certified study researcher who had a higher degree in nursing and extensive experience in practicing and delivering MBIs.
Study NCT06618209 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: physical and chemical methods
Description: Salivary flow rate, pH
Study NCT06618209 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: biochemical methods
Description: Total oxidant and antioxidant capacities, Lactoperoxidase, Oxidative Stress Index, Glutathione, Superoxide Dismutase
Study NCT06618209 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Oral Findings
Description: DMFT/dft Index: Measures decayed, missing, and filled teeth. ICDAS II: International Caries Detection and Assessment System, used for detecting and assessing dental caries. DDE Index: Developmental Defects of Enamel index.GI (Gingival Index): Assesses the severity of gingivitis based on inflammation.PI (Plaque Index): Assesses the severity of plaque based on inflammation. basic erosive wear examination: measures dental erosion
Study NCT06618209 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Pediatric Oral Health Quality of Life
Description: The Pediatric Oral Health Quality of Life (POQL) Scale is a tool used to assess the impact of oral health conditions on the overall quality of life in children.
Study NCT06621628 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: stretching, strengthening exercises and active exercises
Description: Bioptron light therapy device, resisted exercises and stretching exercises