AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sleep Monitoring
Description: Sleep will be assessed by wrist-based acceleration with cloud technology (Polar Unite™, Polar USA). This monitor is less burdensome than other sleep monitoring technologies and less likely to interfere with normal sleep and activity demands of the cadets.Each participant will be fitted with the watch for acclimatization and then establish 3-day baseline patterns for 3 nights before the sleep loss protocol.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Sleep Monitoring
Description: Sleep will be assessed by wrist-based acceleration with cloud technology (Polar Unite™, Polar USA). This monitor is less burdensome than other sleep monitoring technologies and less likely to interfere with normal sleep and activity demands of the cadets.Each participant will be fitted with the watch for acclimatization and then establish 3-day baseline patterns for 3 nights before the sleep loss protocol.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet
Description: Diet will be included and the same meals will be available for all subjects while controlling for caffeine. Participants will be given food during each intervention week.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Diet
Description: Diet will be included and the same meals will be available for all subjects while controlling for caffeine. Participants will be given food during each intervention week.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Performance
Description: Since weight training is now a crucial part of any warfighter's physical preparation, we will have subjects perform weight training workouts emphasizing all major muscle groups on Days 2, 3 and 4
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Exercise Performance
Description: Since weight training is now a crucial part of any warfighter's physical preparation, we will have subjects perform weight training workouts emphasizing all major muscle groups on Days 2, 3 and 4
Study NCT05519644 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Surveys, McGill Pain Questionnaire, Shortened Profile of Mood States, Pittsburg Sleep Index
Description: These will be administered on Days 1 and 5 of each intervention trial to assess different behavioral outcomes.
Study NCT05519644 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Surveys, McGill Pain Questionnaire, Shortened Profile of Mood States, Pittsburg Sleep Index
Description: These will be administered on Days 1 and 5 of each intervention trial to assess different behavioral outcomes.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Cognitive performance
Description: Automated Neuropsychological Assessment Metrics (ANAM), Cambridge Neuropsychological Test Automated Battery. (CANTAB),Gradual-onset Continuous Performance Task (GRAD-CPT),Face-Name Task will be used to assess cognitive function and performance.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Cognitive performance
Description: Automated Neuropsychological Assessment Metrics (ANAM), Cambridge Neuropsychological Test Automated Battery. (CANTAB),Gradual-onset Continuous Performance Task (GRAD-CPT),Face-Name Task will be used to assess cognitive function and performance.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Marksmanship Performance
Description: The Virtual Training Simulator (VirTra V-100) system (VirTra Corporate HQ, Tempe, AZ) is used by both military and law enforcement agencies to provide training. The V-100 and associated compatible weapons are equipped with recoil kits for unsurpassed live-fire simulation, at distances up to 2,000-m, authoring capabilities for the creation of customized scenarios on 4 individual firing lanes. Multiple metrics of marksmanship (total number of shots fired/silhouette target presentation, percentage of targets successfully hit/min, the radial distance of a shot from the center on target, shot group tightness, and time from target presentation to trigger pull) will be collected during each visit.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Marksmanship Performance
Description: The Virtual Training Simulator (VirTra V-100) system (VirTra Corporate HQ, Tempe, AZ) is used by both military and law enforcement agencies to provide training. The V-100 and associated compatible weapons are equipped with recoil kits for unsurpassed live-fire simulation, at distances up to 2,000-m, authoring capabilities for the creation of customized scenarios on 4 individual firing lanes. Multiple metrics of marksmanship (total number of shots fired/silhouette target presentation, percentage of targets successfully hit/min, the radial distance of a shot from the center on target, shot group tightness, and time from target presentation to trigger pull) will be collected during each visit.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Quick Board
Description: Upper body and lower body reaction tests will be assess using Quick Board Analysis on days 1 and 5 of the sleep restriction intervention.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Quick Board
Description: Upper body and lower body reaction tests will be assess using Quick Board Analysis on days 1 and 5 of the sleep restriction intervention.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Advanced Medical Technologies Inc, Jump Test
Description: Whole body power will be assessed with a repetitive jump test. Power (peak, average, curve functions) will be assessed using an AMTI force plate with Accupower 2.0 software (Advanced Mechanical Technology Inc, Watertown, MA).
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Advanced Medical Technologies Inc, Jump Test
Description: Whole body power will be assessed with a repetitive jump test. Power (peak, average, curve functions) will be assessed using an AMTI force plate with Accupower 2.0 software (Advanced Mechanical Technology Inc, Watertown, MA).
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CGM/CKM
Description: Continuous Ketone/Glucose Monitor will be applied at the start of Test Day 1. The sensor will be checked by the study team at each test day and will be removed and replaced by a fresh sensor at \~2- week intervals during the study. The sensor will be removed at the end of the final test day.
Study NCT05519644 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: CGM/CKM
Description: Continuous Ketone/Glucose Monitor will be applied at the start of Test Day 1. The sensor will be checked by the study team at each test day and will be removed and replaced by a fresh sensor at \~2- week intervals during the study. The sensor will be removed at the end of the final test day.
Study NCT05519644 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Blood Draw
Description: Blood samples will be collected according to the schedule in Figure 1.
Study NCT05519644 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Blood Draw
Description: Blood samples will be collected according to the schedule in Figure 1.
Study NCT05519644 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ketone Supplement
Description: Participants will take a diester of hexanoic acid (a ketogenic medium chain fatty acid) and (R)-1,3 butanediol (C6 Di-ester) during one of the trial interventions
Study NCT05519644 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ketone Supplement
Description: Participants will take a diester of hexanoic acid (a ketogenic medium chain fatty acid) and (R)-1,3 butanediol (C6 Di-ester) during one of the trial interventions
Study NCT05597501 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: manual-based group interventions
Description: weekly group interventions (90min) following manuals of either CBT, integrative therapy or existential analysis\&logotherapy
Study NCT05228899 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zofin
Description: 1mL of Zofin will be administered intravenously, containing 2-5 x 10\^11 particles/mL. Zofin will be diluted in 100 mL of sterile saline.
Study NCT05228899 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1mL of Placebo (normal saline) will be diluted in 100 mL of sterile saline and administered intravenously.
Study NCT05095272 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HMPBS02-Pv
Description: The blood-stage P. vivax master cell bank HMPBS02-Pv was also produced using blood collected from a consenting patient with naturally acquired malaria infection. The malaria infection was confirmed to be P. vivax by species-specific PCR at Pathology Queensland (accredited by the Australian National Association of Testing Authorities) and further confirmed by deep sequencing at the Sanger Institute. The clinical response to antimalarial chemotherapy was also demonstrated with this donor, who was successfully cured with artemether/lumefantrine.
Study NCT05681325 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: green tea
Description: It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.
Study NCT05681325 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: matcha tea
Description: It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.
Study NCT05122390 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Contraction Coper
Description: Digital application built on the Birth without fear method, based on four different tools to be used during labour. Breathing, relaxation, voice and mind.
Study NCT05122390 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Contraction Coper
Description: Digital application built on the Birth without fear method, based on four different tools to be used during labour. Breathing, relaxation, voice and mind.
Study NCT05122390 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Contraction Coper Plus
Description: Digital application built on the Birth without fear method, based on four different tools to be used during labour. Breathing, relaxation, voice and mind. Clinical guidance from a midwife during two different occasions is added to the group.
Study NCT05097846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group1 Vonoprazan Fumarate + amoxicillin + doxycycline
Description: Vonoprazan Fumarate + amoxicillin + doxycycline
Study NCT05097846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group2 Vonoprazan Fumarate + furazolidone + doxycycline
Description: Vonoprazan Fumarate + furazolidone + doxycycline
Study NCT05097846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group3 esomeprazole + colloidal bismuth tartrate + amoxicillin + doxycycline
Description: esomeprazole + colloidal bismuth tartrate + amoxicillin + doxycycline
Study NCT05097846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Group4 esomeprazole + colloidal bismuth tartrate + furazolidone + doxycycline
Description: esomeprazole + colloidal bismuth tartrate + furazolidone + doxycycline
Study NCT05165342 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Rexon-eye
Description: a technique in which low-intensity, high-frequency (a spectrum of frequencies ranging from 4 MHz to 64 MHz) electric currents are administered to a biological tissue through contact electrodes
Study NCT05165342 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Rexon-eye
Description: a technique in which low-intensity, high-frequency (a spectrum of frequencies ranging from 4 MHz to 64 MHz) electric currents are administered to a biological tissue through contact electrodes
Study NCT05950893 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: pressure support level
Description: Baseline ventilators were set by the principle of keeping VT/PBW at 6-8ml/kg and RR at 20-30 breaths/min and the decision of the responsible ICU physician. After then the fraction of inspired oxygen (FiO2), positive expiratory end pressure (PEEP), trigger sensitivity, and cycle-off criteria remain unchanged. Downward PS level titration was performed from 20 cmH2O to 2 cmH2O at a 2cm H2O interval. Every PS level was maintained for 20 minutes and then three end-inspiratory holdings (2-3seconds) and three end-expiratory holdings were performed. To avoid additional injury to the lung and diaphragm, the airway peak pressure (Ppeak) was limited to 30cmH2O.Inspiratory effort is measured as pressure generated by inspiratory muscles using esophageal pressure monitoring.
Study NCT05750329 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: assisted liver transplantation combined with two-stage hepatectomy
Description: Stage 1 Surgery: Left Hepatectomy, Left Lateral Graft Implantation, Portal Shunt to Graft Intermediate stage: continuous monitoring of liver function indexes and liver transplant donor volume after the first stage of surgery. Until the graft size reaches 0.8% of body weight (GBWR), or 35%-45% of the standard liver volume.~Stage 2 Surgery: Residual Right Hepatectomy
Study NCT06412627 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: 4°C frozen normal saline gauze
Description: Soak two 4x4 gauze pads in 15 ml of normal saline, refrigerate at 4°C, and then apply in the oral cavity for 15 minutes before removal.
Study NCT05886400 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: SCAT6
Description: The SCAT6 is a standardized assessment tool to diagnose a concussion. This tool will be used for the experiment utilizing the 6th edition to recreate the methods used in an athletic situation. The SCAT6 is broken down into multiple subtests to focus on specific aspects of a person's wellbeing that could be affected by a possible concussion. The assessments are created to measure an athlete's subjectively experienced symptoms, cognitive functioning and balance and postural stability (mBESS).
Study NCT05886400 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: SCAT6
Description: The SCAT6 is a standardized assessment tool to diagnose a concussion. This tool will be used for the experiment utilizing the 6th edition to recreate the methods used in an athletic situation. The SCAT6 is broken down into multiple subtests to focus on specific aspects of a person's wellbeing that could be affected by a possible concussion. The assessments are created to measure an athlete's subjectively experienced symptoms, cognitive functioning and balance and postural stability (mBESS).
Study NCT05886400 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual/ Auditory Distraction
Description: The purpose of this study is to examine the effect of environmental distractions on one's ability to complete the SCAT6. The environmental distractions will be visual and auditory by playing a sports event or sports clips during the completion of the assessment. The goal of this is to simulate the distraction of a sideline like a SCAT6 is typically used within athletic training.
Study NCT04894201 — intervention group
Intervention type: RADIATION
Intervention: Dental Panoramic Radiographs
Description: Exposure to dental panoramic radiographs
Study NCT05389566 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Quantative Sensory Testing
Description: Evaluation of small fiber neuropathy
Study NCT05389566 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: NCStat-DPN-Check
Description: Evaluation of large fiber neuropathy
Study NCT05389566 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Composite Autonomic Symptom Score 31
Description: Evaluation of autonomic neuropathy
Study NCT05072925 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Tobacco products
Description: Products will be used under defined (10 puffs, 30 seconds apart) and ad libitum puffing conditions
Study NCT05072925 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Tobacco products
Description: Products will be used under defined (10 puffs, 30 seconds apart) and ad libitum puffing conditions
Study NCT06296836 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: Continuation of home metformin
Study NCT05933759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Telemedical coaching
Description: Individual telemedical coaching delivered by a nutritional consultant
Study NCT05933759 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Low-Insulin-Method
Description: Lifestyle intervention with education via the Low-Insulin-App, low-carb diet, self-monitoring of weight and steps
Study NCT05933759 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Low-Insulin-Method
Description: Lifestyle intervention with education via the Low-Insulin-App, low-carb diet, self-monitoring of weight and steps
Study NCT05388500 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Paclitaxel + Trastuzumab
Description: Regarding neoadjuvant treatment :~- 9 to 12 weeks of neoadjuvant treatment Trastuzumab IV (8mg/kg loading dose followed by 6 mg/kg maintenance dose) or SubCutaneous (SC) (600mg fixed dose) every 3 weeks + weekly Paclitaxel IV : 80 to 90 mg/m2~Regarding adjuvant treatment patients will receive one of the following anti-HER2 therapy following the current standard to complete 1 year of anti-HER2 therapy in total :~* in case of pCR : patient will receive trastuzumab~* in case of non pCR : patients will receive trastuzumab emtansine (T-DM1)
Study NCT05388500 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Trastuzumab
Description: Regarding neoadjuvant treatment :~- 9 to 12 weeks of neoadjuvant treatment Trastuzumab IV (8mg/kg loading dose followed by 6 mg/kg maintenance dose) or SC (600mg fixed dose) every 3 weeks~Regarding adjuvant treatment patients will receive one of the following anti-HER2 therapy following the current standard to complete 1 year of anti-HER2 therapy in total :~* in case of pCR : patient will receive trastuzumab~* in case of non pCR : patients will receive trastuzumab emtansine (T-DM1)
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Docetaxel
Description: Docetaxel 50 mg/m2 intravenously on day 1
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxaliplatin
Description: Oxaliplatin 85 mg/m2 on Day 1
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Oxaliplatin
Description: Oxaliplatin 85 mg/m2 on Day 1
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium folinate
Description: 200 mg/m2 2-hour intravenous infusion on day 1
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium folinate
Description: 200 mg/m2 2-hour intravenous infusion on day 1
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Fluorouracil
Description: 2600 mg/m2 x intravenous infusion 24-hours (infusion of the samee of the total dose of fluorouracil for 48 hours) on day 1.
Study NCT06313801 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorouracil
Description: 2600 mg/m2 x intravenous infusion 24-hours (infusion of the samee of the total dose of fluorouracil for 48 hours) on day 1.
Study NCT06313801 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Diagnostic laparoscopy
Description: Access to the abdominal cavity by Hassen (3 trocars). Carboxyperitoneum - 12 mm of water column - stable pressure maintenance throughout the operation. Revision. Photo recording of 4 quadrants of the abdominal cavity from the paraumbilical port. The evaluation of the PCI index. The evaluation of other distant dissemination. Standard peritoneal lavage of 300 ml Sol. NaCl 0.9 % (37 ºС), with the exposure of 3-5 minutes (with Trendelenburg and Fowler position alternately) and the lavage aspiration, the transfer of the lavage for the cytological examination. Biopsy of perioneal lessions if needed.The operation is completed as standard with the extraction of laparoports and suturing of laparoport wounds.
Study NCT06313801 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Diagnostic laparoscopy
Description: Access to the abdominal cavity by Hassen (3 trocars). Carboxyperitoneum - 12 mm of water column - stable pressure maintenance throughout the operation. Revision. Photo recording of 4 quadrants of the abdominal cavity from the paraumbilical port. The evaluation of the PCI index. The evaluation of other distant dissemination. Standard peritoneal lavage of 300 ml Sol. NaCl 0.9 % (37 ºС), with the exposure of 3-5 minutes (with Trendelenburg and Fowler position alternately) and the lavage aspiration, the transfer of the lavage for the cytological examination. Biopsy of perioneal lessions if needed.The operation is completed as standard with the extraction of laparoports and suturing of laparoport wounds.
Study NCT06313801 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: dPIPAC ( The description of the standard diagnostic laparoscopy procedure and the session of PIPAC (dPIPAC)).
Description: Diagnostic laparoscopy described earlier and PIPAC session. The drugs for PIPAC - Docetaxel 50 mg/ m2 diluted with saline sodium chloride to a total volume of 200 ml. The rate of administration is 30 ml per minute. The maximum pressure in the injector system is 250 PSI. After the spray stage, the exposure is 30 minutes while maintaining the declared intraperitoneal pressure. After the exposure stage, only gas is removed from the abdominal cavity. The operation is completed as standard with the extraction of laparoports and suturing of laparoport wounds.
Study NCT04745481 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Trunk stabilization training device
Description: Conventional rehabilitation 30min daily, 20times 4weeks~+Trunk stabilization training device 30min daily, 20time 4weeks
Study NCT04745481 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Conventional rehabilitation
Description: Conventional rehabilitation 30min daily, 20times 4weeks~+Conventional rehabilitation 30min daily, 20times 4weeks