AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04963673 — intervention group
Intervention type: OTHER
Intervention: calcineurin inhibitor dosage
Description: The dosage of calcineurin inhibitors will be done as usual by the toxicology pharmacology laboratory of the CHU Amiens-Picardie. If the patient does not object, the determination of protein-bound uremic toxins from the rest of the collected blood tube will be performed using high performance liquid chromatography.
Study NCT06131541 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: autogenous tooth graft
Description: undemineralized autogenous tooth graft will augment the gap between the splitted ridge and the simultaneously \[laced implant fixture
Study NCT06131541 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: autogenous bone graft
Description: autogenous bone graft will augment the gap between the splitted ridge and the simultaneously \[laced implant fixture
Study NCT05414838 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Curcumin, Omega-3 and Vitamin-D (COD)
Description: Acumin™ Turmeric Complex (Dr. D's Ultra BioTurmeric) 500 mg daily (NPN 80087842)~Omega-3 supplements (combination of DHA and EPA) 900 mg daily (NPN 80019234)~Vitamin D3 supplements 2500 IU daily (NPN 80108995)
Study NCT05406206 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fruquintinib
Description: Fruquintinib is a capsule in the form of 1mg and 5mg, once a day, 3 week on/1 week off.
Study NCT05406206 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Hepatic Arterial Infusion Chemotherapy
Description: HAIC is a locoregional therapy for colorectal cancer liver metastasis. Oxaliplatin 85 mg/m\*2 + 5-FU 2000 mg/m\*2, Q4W
Study NCT05889819 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Almond orange potato cookies for stunted under-five children
Description: Trained enumerator distributed 50 g cookies three times a week during 30 days to the treatment group.~Anthropometry measurement: weight and height measured at pre study, during study (once a week), and post study.
Study NCT05889819 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Almond orange potato cookies for stunted under-five children
Description: Trained enumerator distributed 50 g cookies three times a week during 30 days to the treatment group.~Anthropometry measurement: weight and height measured at pre study, during study (once a week), and post study.
Study NCT05412459 — intervention group
Intervention type: DRUG
Intervention: 99mTc-DARPinG3
Description: Diagnostic test (99mTc-DARPinG3-based SPECT) is used for the assessment of the effect of anticancer therapy.
Study NCT05258747 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Olaparib tablets, 150 mg
Description: Olaparib tablets, 150 mg of Lek Pharmaceuticals d.d., Slovenia
Study NCT05258747 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Lynparza® (olaparib) tablets 150 mg
Description: Lynparza® (olaparib) tablets 150 mg Manufactured for: AstraZeneca Pharmaceuticals LP, Wilmington, Delaware (DE).
Study NCT06211062 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Floradapt Intensive GI
Description: one capsule daily for the eight week intervention
Study NCT06211062 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: one capsule daily for the eight week intervention
Study NCT05905991 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Enhanced Stress Resilience Training
Description: The ESRT intervention will consist of 1) five weekly one-hour sessions (in-person or virtual) led by a certified instructor; 2) smartphone-based exercises that bring informal practice into daily life; 3) videos on principles and concepts taught each week; and 4) meditation recordings of various lengths and styles supporting the prescribed daily practice of up to 20 min/day. Weekly didactic and experiential activities will cover mindfulness-based intervention concepts and skills, such as cultivating resilience, awareness of the body, managing thoughts, responding versus reacting, transforming circumstances, and advocacy through mindful communication. The ESRT smartphone app (Mindful Brian) houses all course materials (pre-class materials and post-class materials) and sends class reminders and messages. Considering nurses' shifts, ESRT will be offered in two separate sessions each week.
Study NCT05905991 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Enhanced Stress Resilience Training
Description: The ESRT intervention will consist of 1) five weekly one-hour sessions (in-person or virtual) led by a certified instructor; 2) smartphone-based exercises that bring informal practice into daily life; 3) videos on principles and concepts taught each week; and 4) meditation recordings of various lengths and styles supporting the prescribed daily practice of up to 20 min/day. Weekly didactic and experiential activities will cover mindfulness-based intervention concepts and skills, such as cultivating resilience, awareness of the body, managing thoughts, responding versus reacting, transforming circumstances, and advocacy through mindful communication. The ESRT smartphone app (Mindful Brian) houses all course materials (pre-class materials and post-class materials) and sends class reminders and messages. Considering nurses' shifts, ESRT will be offered in two separate sessions each week.
Study NCT05625581 — intervention group
Intervention type: DRUG
Intervention: tofacitinib
Description: All subjects were treated immediately after non randomized enrollment. The treatment scheme of the experimental group: glucocorticoid+tropitib; the treatment scheme of the control group: glucocorticoid+cyclophosphamide.
Study NCT05235763 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: activity coach
Description: The activity coach educates the patient about physical activity, offers means of manually tracking physical activity, and provides trends of registered activity. Furthermore, it provides weekly summaries of registered physical activity and provides means of setting goals for the following week.
Study NCT05235763 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: sham activity coach
Description: The visual appearance of Optilogg is changed as to make the patient aware that something has happened to it, hence not knowing if it is the real activity coach or not. No new functionality is added, however.
Study NCT06341426 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Single Psychedelic Dose Psilocybin
Description: One psychedelic dose (1mg of psilocybin + 25mg of psilocybin) taken in conjunction with psilocybin-assisted psychotherapy
Study NCT06341426 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Two Psychedelic Doses Psilocybin
Description: Two psychedelic doses (25 mg of psilocybin + 25mg of psilocybin) taken in conjunction with psilocybin-assisted psychotherapy
Study NCT04706741 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Izokibep
Description: Izokibep is an Interleukin-17 Inhibitor that will be administered subcutaneously
Study NCT04706741 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone/Prednisolone
Description: Background Corticosteroid
Study NCT06437730 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Integrated Neuromuscular Inhibition Technique:
Description: MTrPs points will be released with ischemic compression, position of ease will be acquired, and in the last METs will be performed. Ischemic compression applied through thumb on trigger point present in any muscle around the knee joint. Compression will be increased gradually until first resistance will feel and maintained until it resolves, further increases then until no tissue resistance will be felt under thumb. This process is maintained for 30sec and repeated 3-5 times per session. Positional release technique: after applying pressure on trigger point, patient will acquire position of ease that is maintained for 20 sec whether its extension or flexion of knee. This process is repeated 3-5 times per session. Muscle Energy Technique will be applied on the muscle in which isometric contraction is maintained for 7-10sec against 20-25% strength. After completion of muscular contraction, the limb is moved away for muscular stretch and then position is maintained for 30 seconds
Study NCT06437730 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Dry needling:
Description: Dry needle will be targeting trigger points (TrPs) using in-and-out techniques such as 'pistoning' or 'sparrow pecking'. 0.25x25mm needle is inserted.~For vastus laterals patient is supine line with knee extended performing an isometric quadriceps contraction, maintaining a clean technique by using gloves and performing an alcohol wipe down bracket the tissue to be treated and inserting needle with direct approach towards the femur, performing pistoning. For vastus medialis patient is supine line with 30 degrees of knee flexion. A headless 0.25x25mm needle fixed between the fingers of non-dominant hand and inserted perpendicularly to the MTrPs with metacarpophalangeal flexion extension of 1st and 2nd fingers of dominant hand. For Gastrocnemius patient is prone lying and bolstered supported slight knee bend, for the upper part anterior medial approach is used and center of muscle belly slight medial anterior approach is used.
Study NCT05522751 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: DBS
Description: Bilateral DBS electrodes will be implanted into the limbic pallidum of participants with severe alcohol use disorder and advanced but compensated liver disease.
Study NCT05591469 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: IR Camera
Description: the respiration parameters are measured using an IR camera.
Study NCT05591469 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electrical Impedance Tomography
Description: the respiration parameters are measured using an electrical impedance tomograhy.
Study NCT05521295 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention in this study
Study NCT05540743 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: biologic DMARDs
Description: follow up the clinical response in Egyptian population to the drug
Study NCT05913206 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Complexity
Description: The intervention is a novel communication approach to communicate complexity related to the potential risks and benefits associated with clinical decision making for parents and caregivers of children with medical complexity.
Study NCT05913206 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Normalizing language
Description: The intervention is a novel communication approach to normalize and explain the inherent uncertainty faced by parents of children with medical complexity during clinical decision making.
Study NCT05913206 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Narrative
Description: Parent and caregiver narratives about their decision making experiences for the care of their child with medical complexity.
Study NCT06271603 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: diagnosis based on deepLive™ LC-OCT device
Description: Management of BCC with an initial diagnosis based on the deepLive™ device using LC-OCT technology.
Study NCT06271603 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: ACTIVE_COMPARATOR
Intervention: diagnosis based on skin biopsy
Description: Control Arm: Standard management with an initial diagnosis based on skin biopsy
Study NCT06215924 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Reverse Kegel exercise
Description: In addition to the training given by the physician, patients will be taught the 'Reverse Kegel' exercise. The 'Reverse Kegel' exercise is an exercise that is used to relax the pelvic floor muscles. To practice the exercise, patients will be asked to lie in a supine position with a support under the knees. In this position, patients will be asked to relax the pelvic floor muscles while breathing through their nose, maintain this movement for 5 seconds, and tighten the pelvic floor muscles while exhaling. Patients will be advised to do this exercise for 5 sets, 10 repetitions during the day. On the day of the training, initial evaluations will be made to the patients before the exercise training is given. Evaluations will be repeated at the end of the second and fourth week.
Study NCT05116865 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HH-120 Dose 1
Description: Dose level 1 of HH-120
Study NCT06215924 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Postisometric Relaxation Technique
Description: In addition to training given by the physican, internal digital Postisometric Relaxation method will be applied to the patients in this group from the anal region. Application will be made to the muscles where muscle spasm, movement restriction and pain are detected. The patient will be asked to perform a contraction against the digital resistance with maximum force and maintain this contraction for 5 seconds, actively relax after 5 seconds. During relaxation, stretching will be applied for 30 seconds by digitally supporting the movement of the pelvic floor muscles. The process will be performed with 5 repetitions. The application will be made 2 days a week for 4 weeks. On the day of the training, initial evaluations will be made to the patients before the exercise training is given.Evaluations will be repeated at the end of the second and fourth week.
Study NCT05700812 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Sound sparing levonorgestrel 52 mg IUD placement
Description: In phase one, the IUD will be placed in a standard fashion with the use of a uterine sound to obtain baseline data.~In the experimental phases of the study (phase 2 and 3) the levonorgestrel 52 mg IUD will be placed without the use of a uterine sound. In phase 2 the IUD will be placed under abdominal ultrasound guidance. In phase 3 the IUD will be placed without abdominal ultrasound guidance.
Study NCT06629298 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 5Hz Stochastic Resonance Whole-Body Vibration Training
Description: Both the experimental group and the control group performed their training on an SRT Zeptor® Medical plus noise device (Frei Swiss AG, Zurich). The device featured two independent foot plates that vibrated stochastically in all three dimensions, resulting in multidimensional movement. During the training, participants were instructed to stand on the foot plates with both feet, keep their arms relaxed at their sides, maintain a slight bend in their knees, and focus their gaze on a fixation cross on the wall. Following the protocol used in Faes et al. (2018), each training session consisted of three series, each comprising one minute of vibration training followed by one minute of rest.~The vibration frequency for the intervention group was set at 5 Hz.
Study NCT06629298 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: 2 Hz Stochastic Resonance Whole-Body Vibration Training
Description: Both the experimental group and the control group performed their training on an SRT Zeptor® Medical plus noise device (Frei Swiss AG, Zurich). The device featured two independent foot plates that vibrated stochastically in all three dimensions, resulting in multidimensional movement. During the training, participants were instructed to stand on the foot plates with both feet, keep their arms relaxed at their sides, maintain a slight bend in their knees, and focus their gaze on a fixation cross on the wall. Following the protocol used in Faes et al. (2018), each training session consisted of three series, each comprising one minute of vibration training followed by one minute of rest.~The vibration frequency for the intervention group was set at 2 Hz.
Study NCT05387460 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: radiomics
Description: Radiomics refers to high-throughput mining of quantitative image features from medical imaging. Radiomics derived data, when combined with other pertinent clinicopathological features, can produce accurate and robust evidence-based decision-making systems. Multimodal radiomics can provide more imaging feature information than single modal radiomics, which showed better diagnostic performance in previous study of kinds of cancer diseases.
Study NCT04826887 — intervention group
Intervention type: OTHER
Intervention: SOLTIVE Thulium Laser
Description: Use of SOLTIVE Thulium laser for HoLEP
Study NCT04826887 — intervention group
Intervention type: OTHER
Intervention: Standard of Care (Holmium Laser)
Description: Use of Holmium laser for HoLEP
Study NCT06292858 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IMB071703 injection
Description: Intratumoral injection
Study NCT05729399 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GT201
Description: Autologous tumor infiltrating lymphocyte injection
Study NCT05146986 — intervention group
Intervention type: DEVICE
Intervention: Non surgical and Surgical
Description: For non-surgical group, patients will receive non-surgical treatment (analgesia and symptomatic management treatment).~For surgical group, patients will receive surgical treatment using RibFix Blu Thoracic Fixation System.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Fiberoptic Endoscopic Evaluation of Swallowing
Description: This procedure involves inserting a flexible laryngoscope that contains a light source and video camera on the end through the open passage of the nose towards the back of the throat in order to visualize the swallowing mechanism.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Videofluoroscopic Swallowing Study
Description: Videofluoroscopic swallowing study will be performed to measure oropharyngeal swallowing. This is like a moving x-ray of the swallow.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Voluntary Peak Cough Flow Testing
Description: Voluntary peak cough flow testing will be performed to determine the peak expiratory flow (PEF) and volume of air expelled (FEV1) during voluntary coughing.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Iowa Oral Performance Instrument
Description: The Iowa Oral Performance Instrument (IOPI) is a device that measures the peak pressure performance of lingual strength and endurance via the action of a bulb placed on the hard palate.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Capsaicin Challenge
Description: A capsaicin challenge with three randomized blocks of 0, 50, 100, 200, and 500 μM capsaicin. The capsaicin will be dissolved in a vehicle solution consisting of 80% physiological saline, and 20% ethanol. Participants will be given the instruction cough if you need to prior to capsaicin delivery.The solution will be administered automatically upon detection of an inspired breath and there will be a minimum of one minute between each trial. This is to test the reflexive cough testing for upper airway sensitivity and motor thresholds.
Study NCT04773184 — intervention group
Intervention type: PROCEDURE
Intervention: Pulmonary Function Testing
Description: Pulmonary Function testing will be performed using conventional methods and will include the following outcomes: forced vital capacity (FVC), maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP) expressed as a percentage of predicted values.
Study NCT04773184 — intervention group
Intervention type: OTHER
Intervention: Voicing Tasks
Description: Voicing tasks will be completed to assess vocal ability.
Study NCT06313086 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DP303c
Description: intravenous injection
Study NCT06313086 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: trastuzumab emtansine
Description: intravenous injection
Study NCT06329960 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ultrasound-guided injection combined with needle release
Description: Ultrasound-guided PIT using D5W HD for dorsal scapular nerve combined with needle release of major and minor rhomboideus
Study NCT05853367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-0472
Description: Oral Administration
Study NCT05853367 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: IV infusion
Study NCT05853367 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: MK-1084
Description: Oral Administration
Study NCT05728853 — intervention group
Intervention type: RADIATION
Intervention: Assessment of body composition
Description: Assessment of body composition using BIA and DXA
Study NCT06514053 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Full pulpotomy
Description: A full pulpotomy will be performed by removing the entire roof of the pulp chamber and the remaining pulp tissue will be covered by Biodentine.
Study NCT06514053 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Root canal treatment
Description: The regular procedure of root canal treatment will be performed on teeth with irreversible pulpitis
Study NCT06066346 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Talquetamab
Description: Talquetamab will be administered SC until disease progression
Study NCT05856994 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tacrolimus ointment
Description: For the active comparator group, the wound(s) will be cleaned and bacitracin ointment will be applied to the wound. External dressings on all treated wounds will be placed based on the current standard of care. For the control group, the wound(s) will be cleaned and a hydrocolloid Dressing will be affixed to the burn and treated area. For the treatment group, the wound(s) will be cleaned and tacrolimus (0.03%) ointment will be applied over the burn. Hydrocolloid Dressing will be affixed to the burn and treated area. External dressings on all treated wounds will be placed based on the current standard of care.
Study NCT05497388 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Serious Game
Description: using Serious Game for HCV education
Study NCT06232057 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Women in the intervention group will be given a pre-test (STAI) before cesarean. Then, they will be shown a relaxing video (video with nature views accompanied by nature sounds) through virtual reality glasses for a maximum of 20 minutes. After a cesarean, women's anxiety levels (STAI) will be evaluated within the first 4 hours postoperatively. Pain levels (VAS) will be assessed postoperatively at the 2nd, 4th, and 6th hours.