AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02434835 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [14C]KWA-0711
Study NCT05528237 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Flocked swab paired with Roche Cobas 4800
Description: Consenting individuals will insert the sterile flocked swab into the vagina, rotate at least once, and store in the provided dry tube. The sample will be stored at ambient temperature and routed to the lab for HPV testing with Roche Cobas 4800.
Study NCT05197504 — intervention group
Intervention type: DRUG
Intervention: atezolizumab plus bevacizumab
Description: 1200 mg of atezolizumab plus 15 mg/kg of body weight of bevacizumab intravenously every 3 weeks
Study NCT05352828 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nivolumab
Description: Dose: 480 mg or 6 mg/kg Q4W
Study NCT05352828 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous CD30.CAR-T
Description: Dose: 2 x 10e8 cells/m2
Study NCT05352828 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: Dose: 30 mg/m2/day x 3 days
Study NCT05352828 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bendamustine
Description: Dose: 70 mg/m2/day x 3 days
Study NCT06361199 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proximod
Description: Multiple-dose to establish the safety and PK profile in both healthy subjects and patients with rheumatoid arthritis
Study NCT06361199 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo controlled
Study NCT05378620 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Project Dulce + Dulce Digital
Description: Project Dulce will consist of a group diabetes self-management program consisting of a 5-week curriculum delivered by a peer educator in Tagalog. The curriculum provides new knowledge as well as skills and tools needed to adapt to a life with diabetes and change behaviors. The curriculum covers diabetes and its complication, the role of diet, exercise, and medication, and the importance of self-monitoring. It is presented over 5 weeks where participants will learn and practice self-management skills, and help one another address family, cultural, or health system barriers to managing your diabetes. Following the 5-week curriculum, participants will be enrolled in the digital texting platform, Dulce Digital, in which they will receive on-going support via text messages derived from the curriculum, medication reminders, and blood glucose monitoring prompts in Tagalog.
Study NCT06582979 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computer-Based Game Therapy
Description: Computer-based game intervention will be done three times a week, every morning before school lessons begin or during break time. Researchers will give a brief explanation of the rules on how to play the game before the intervention begins. In the game, participants will act as a fruit truck delivery driver and will have to sort out fruit delivery to different houses according to the instructions of the game. For example, the instruction starts with delivering a yellow-colored banana to a house with a red-colored roof, or delivering a purple-colored grape to a house with a blue-colored roof. Participants will first have to finish a minimum of three tutorial rounds reaching ≥75% correct delivery. Instructions will be divided into four stages; visual stimulus, auditory stimulus, visual stimulus with an obstacle, auditory stimulus with an obstacle. Each round will last for 2 minutes. Total time needed to complete a single computer-based intervention session is around 30-45 minutes.
Study NCT06582979 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High-Intensity Interval Training
Description: HIIT will be done two times a week during physical education hours (in the school's sports field) led by the school's physical education teacher and also certified physical trainers who have undergone training supervised by a sports medicine physician. Before the start of each HIIT session, participants will have their pulse rate assessed with a pulse oximetry and then undergo warm-up for 5 minutes. The duration of each HIIT session will be continuously extended starting at around 4 minutes (1 tabata block/8 moves) during the first week to 8 minutes (2 tabata block/16 moves) during the final week. A single tabata block moveset incorporates 8 total moves; squat jump, push up, high skipping, burpees, isometric front plank, multi jumps on bench, mountain climber in hand plank and lateral sprint (5m). Each move will be done for 20 seconds, followed by a 10 second rest. Pulse rate will be assessed again after the HIIT session and then participants will undergo cooling down and relaxation.
Study NCT06322784 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Oat bran (dietary fiber)
Description: Dietary fiber, known as the seventh type of nutrients, refers to carbohydrate polymers that have health benefits for the human body, mainly derived from plant cell walls such as grains, fruits, and vegetables.Mediterranean cuisine is a dietary pattern
Study NCT06581458 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: tDCS
Description: The immediate intervention group will continue to receive five tDCS treatments per week for 6 months. The late intervention group will receive five sham treatments per week for 3 months and then begin receiving five weekly tDCS treatments for an additional 3 months.
Study NCT06255535 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: active iTBS treatment
Description: Participants will undergo three iTBS sessions per day, with 1800 pulses per session, over a 12-week period. Individualized targets will be generated using the pBFS technique.
Study NCT06255535 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: sham iTBS treatment
Description: Participants will undergo three iTBS sessions per day, with 1800 pulses per session, over a 12-week period. Sham stimulation will be delivered through a sham coil with the identical appearance as real coil. Individualized targets will be generated using the pBFS technique.
Study NCT06098976 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Manual toothbrush
Description: Manual toothbrush: The patients were taught to use the modified vertical method, and the patient brushed the teeth of the upper and lower jaws using traditional toothbrushes (Diamond, JolleyDent, Damascus, Syria), and anti-plaque toothpaste (Elgydium, UniPharma Co., Ltd, Ashrafiyat Sahnaya, Syria).
Study NCT04914182 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: LASER
Description: Laser will be applied in specific points for perineal lacerations.
Study NCT04914182 — intervention group
Intervention type: RADIATION
Group type: SHAM_COMPARATOR
Intervention: CONTROL
Description: A control group of sham laser will create for the patients the impression that laser is being played, with the lights of the instrument of on mode turned on, without biological effects.
Study NCT06581458 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tDCS
Description: The immediate intervention group will continue to receive five tDCS treatments per week for 6 months. The late intervention group will receive five sham treatments per week for 3 months and then begin receiving five weekly tDCS treatments for an additional 3 months.
Study NCT06583070 — intervention group
Intervention type: RADIATION
Intervention: Radiation therapy
Description: Administer radiation therapy to achieve as complete coverage as possible of all identifiable primary and metastatic lesions in conjunction with targeted and immunotherapy
Study NCT05959278 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: App for vestibular rehabilitation
Description: This app is a platform for performing conventional vestibular rehabilitation remotely
Study NCT04941092 — intervention group
Intervention type: OTHER
Intervention: no intervention
Description: no intervention, retrospective comparison
Study NCT06094075 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Resistance training based on DSI value
Description: The intervention consist of modifying the ongoing resistance exercises. Those with low DSI values will perform ballistics, explosive exercises. Those with high DSI will perform heavy-load training. The resistance training program will consist of 2 sessions per week for 5 weeks (10 sessions in total). The sessions will be separated by a minimum of 48 hours. The strength training group will consist mostly of exercises with high load, whereas the ballistic training group will perform ballistic exercises with low load or without any additional load. The training principle will be the same for both subgroups, consisting of 3 exercises per training session and a total of 6 exercises per week, with four of the exercises being bilateral, one unilateral, and one quasi-unilateral (Bulgarian split squat and scissor jumps).
Study NCT06094075 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Normal training group
Description: The participants will do a general training program (not based on DSI values). The resistance training program will consist of 2 sessions per week for 5 weeks (10 sessions in total). The sessions will be separated by a minimum of 48 hours. The strength training group will consist mostly of exercises with high load, whereas the ballistic training group will perform ballistic exercises with low load or without any additional load. The training principle will be the same for both subgroups, consisting of 3 exercises per training session and a total of 6 exercises per week, with four of the exercises being bilateral, one unilateral, and one quasi-unilateral (Bulgarian split squat and scissor jumps).
Study NCT06115525 — intervention group
Intervention type: OTHER
Intervention: mNUTRIC score
Description: The mNUTRIC score is a useful means of gauging the nutritional risk of patients in intensive care. Originally designed for IC unit patients, the score is calculated even when patient cooperation is unfeasible, making it applicable for intubated patients. Information necessary for calculation can be obtained from the patient's kin. The mNUTRIC score (without IL-6) classifies patients according to predefined metrics. The following information is necessary: (1) the patient's age, (2) their APACHE II score, (3) their SOFA score, (4) their comorbidities, and (5) the number of days they were hospitalized before being admitted to ICU.
Study NCT06115525 — intervention group
Intervention type: OTHER
Intervention: NRS-2002
Description: The NRS-2002 score is a tool utilised to measure the nutritional risk of patients in intensive care units. This tool was specifically developed for the purpose of evaluating intensive care unit patients and can be calculated without requiring the patient's active involvement. Additionally, it can be applied to patients who have been intubated and the required information can be sourced from their family members or relatives. The Nutritional Risk Screening (NRS)-2002 assesses a patient's nutritional risk based on five variables: (1) recent unexplained weight loss, (2) appetite, (3) BMI, (4) disease-related stress factors (comorbidities), and (5) age over 70 years which is an additional risk factor.
Study NCT05320172 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous platelet rich plasma eye drops
Description: Fifty milliliters of patient's own whole blood will be placed in five 10-ml vacutainer tubes containing anticoagulant-citrate-dextrose solution (1.4 ml) and centrifuged at 200g for 11 min. The upper two layers of the centrifuged blood, the plasma and buffy coat layer will be separated in a sterile manner and diluted to 20 % (v/v) with a sterile saline solution. The final preparation is divided into 5-ml bottles wrapped in aluminum foil for protection from ultraviolet light. The patients are instructed to store these bottles at -20 °C until required. The bottles being used will be maintained under refrigerated conditions at 4 °C.
Study NCT04826640 — intervention group
Intervention type: OTHER
Intervention: Observational
Description: Observational
Study NCT05330260 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: neurocognitive test battery
Description: Assessment of the incidence of late postoperative cognitive decline (LPOCD)
Study NCT06394414 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: YL201
Description: YL201 (High dose, medium dose and low dose; Q3W) in Combination with Serplulimab (4.5mg/kg; Q3W) with or without Platinum(70 mg/m2; Q3W)-based Chemotherapy.
Study NCT05516355 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction
Description: The MBSR is an 8-week standardized program (Kabat-Zinn,1990).~During the retreat, participants will receive intensive training during 3 days (from 4:00pm to 9pm the first day and from 7 am to 10 pm including breaks, the second and third days), including focused attention on the breath, open monitoring of awareness in body-scanning, prosocial meditation (i.e. loving kindness and compassion) and gentle yoga. Training is delivered by certified instructors by the University of Massachusetts Centre for Mindfulness (https://www.umassmed.edu/cfm/).
Study NCT06131931 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CLP Intervention
Description: 4 weekly sessions lasting approximately 60 minutes that will be audio recorded for quality assurance. Each couple will be assigned one RA who will serve as their facilitator and guide them through the Connecting Latinxs en Pareja (CLP) sessions. The RA will deliver the appropriate intervention in either Spanish or English at the couple's preference. Sessions will be delivered via zoom (or comparable secure platform), using established procedures from the team's prior studies. Each participant will complete Qualtrics assessments at baseline, 3-, 6- and 9-months post randomization and biological (hair biomarkers for PrEP and ART adherence) and behavioral and psychosocial data collected.
Study NCT06131931 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: WP Intervention
Description: 4 weekly sessions lasting approximately 60 minutes that will be audio recorded for quality assurance. Each couple will be assigned one RA who will serve as their facilitator and guide them through the Wellness Promotion (WP) sessions. The RA will deliver the appropriate intervention in either Spanish or English at the couple's preference. Sessions will be delivered via zoom (or comparable secure platform), using established procedures from the team's prior studies. Each participant will complete Qualtrics assessments at baseline, 3-, 6- and 9-months post randomization and biological (hair biomarkers for PrEP and ART adherence) and behavioral and psychosocial data collected.
Study NCT05852574 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CP-101
Description: CP101 is an investigational oral microbiome drug designed to deliver a complete and functional microbiome to durably repair intestinal dysbiosis, which is being evaluated for the prevention of recurrent CDI.~CP101 contains live microbial communities, derived from rigorously screened human donor stool that is tested, stabilized, characterized, and formulated into capsules designed specifically for delivery into the small bowel for release, to avoid potential degradation by gastric acid.
Study NCT05852574 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: CP-101 + Placebo
Description: The placebo in this trial will be presented in capsules that are identical in size, smell, texture, and appearance to those of the CP101 capsules. These will be produced by the BWH investigational drug service
Study NCT05546515 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Suvorexant (dual orexin receptor antagonist)
Description: Participants will be prescribed up to 30 days of SUVO.
Study NCT05546515 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be prescribed up to 30 days of placebo medication.
Study NCT06150664 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CTX-8371
Description: Intravenous (IV) infusion (0.1-10.0 mg/kg) every two weeks.
Study NCT05514158 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC48-ADC
Description: RC48 for injection is a novel antibody-drug conjugate, with a her-2-targeting antibody and a microtube inhibitor
Study NCT05514158 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RC98
Description: RC98 is a recombinant humanized IgG1 monoclonal antibody targeting programmed cell death-Ligand 1 (PD-L1)
Study NCT06180109 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Empagliflozin film coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin
Study NCT06180109 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Empagliflozin film coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin
Study NCT06180109 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Jardiance film-coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin
Study NCT06180109 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Jardiance film-coated tablets
Description: 1 film coated tablet of 25 mg Empagliflozin
Study NCT05629663 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AR guidance with Hololens 2
Description: The AR instructions were developed as a step-by-step guide, utilizing the dynamic 365 Guide (Software, Microsoft Corporation, Redmond, WA, USA). The AR instructions were delivered using the Microsoft HoloLens 2.
Study NCT05096000 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: InterMob: a randomized controlled trial aimed at reducing car use in regular car users
Description: Intermob is a theory- and evidence-based behavioral intervention that combines public transport/bicycle and motivational techniques (action planning, personalized transport advice, goal setting).
Study NCT05096000 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Active control: Air pollution information
Description: The active control intervention is based on a discussion about air pollution, the effects of air pollution on health, the association between air pollution and transport.
Study NCT05870878 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Standard care
Description: Individual lifestyle consultation
Study NCT05870878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standard care
Description: Individual lifestyle consultation
Study NCT05870878 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lifestyle program
Description: Lifestyle program focusing on lifestyle advice, coping with stress and adherence to a healthy(er) lifestyle. This program consists of 3 group sessions and an online platform.
Study NCT05880498 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness Intervention
Description: Self-guided mindfulness training using a customized version of the Healthy Minds app
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Counseling
Description: Receive call from health coach
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Exercise Intervention
Description: Undergo routine exercise
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Internet-Based Intervention
Description: Receive Android tablet
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Interview
Description: Complete a qualitative interview
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Medical Device Usage and Evaluation
Description: Wear Garmin Vivofit and Nonin 3150 WristOx2 pulse oximeter
Study NCT04307628 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Walnut
Description: Study participants will eat 2 ounces of walnuts each day.
Study NCT04307628 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Nut-Free
Description: Study participants will not eat nuts.
Study NCT05407038 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT06385054 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Probiotic
Description: Participants will be taking 1 sachet a day, at a similar time every day, dissolved in 10 ml of lukewarm water.
Study NCT06385054 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants will be taking 1 sachet a day, at a similar time every day, dissolved in 10 ml of lukewarm water.
Study NCT06297382 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ChatGPT Based Nursing Process Training
Description: ChatGPT Based Nursing Process Training topics:~Lesson 1: Use of artificial intelligence and ChatGPT in healthcare Lesson 2: Using ChatGPT in determining nursing diagnoses and goals Lesson 3: Using ChatGPT to determine nursing interventions Lesson 4: Things to consider and ethical principles when using ChatGPT when creating a nursing process.
Study NCT05310812 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Biochemical evaluation.
Description: Blood will be taken for biochemical evaluation-ELISA.
Study NCT06181513 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Probiotic Blend Capsule
Description: 20 million CFU (Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus helveticus, Bifidobacterium breve)
Study NCT06181513 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Probiotic Blend Capsule
Description: 20 million CFU (Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus helveticus, Bifidobacterium breve)