AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02476396 — intervention group
Intervention type: PROCEDURE
Intervention: Carotid Endarterectomy or Stenting
Description: Carotid endarterectomy is a procedure to treat carotid artery disease. This disease occurs when fatty, waxy deposits build up in one of the carotid arteries. The carotid arteries are blood vessels located on each side of your neck (carotid arteries).~This buildup of plaques (atherosclerosis) may restrict blood flow to your brain. Removing plaques causing the narrowing in the artery can improve blood flow in your carotid artery and reduce your risk of stroke.~In carotid endarterectomy, you an anesthetic. Your surgeon makes an incision along the front of your neck, opens your carotid artery and removes the plaques that are clogging your artery. Your surgeon then repairs the artery with stitches or a patch made with a vein or artificial material (patch graft).~Source: Mayo Clinic~Carotid stenting uses a expandable metal coil to prevent the artery from narrowing.
Study NCT03058068 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allo-hMSCs
Description: 1 peripheral intravenous infusion of allogeneic human mesenchymal stem cells (hMSCs)
Study NCT03058068 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 1 peripheral intravenous infusion
Study NCT03777189 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Therapy
Description: Cognitive-behavioral therapy will be delivered in line with recommendations (e.g., NICE 2017). Format will be guided self help with added content related to physical activity.
Study NCT04155996 — intervention group
Intervention type: DEVICE
Intervention: data collection
Description: Patients will receive a full data acquisition set with CGM sensors, an activity tracker and a smartphone application in which they can log daily events.
Study NCT03261349 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ledipasvir and sofosbuvir
Description: To assess whether Harvoni® (ledipasvir and sofosbuvir) could eradicate HCV and lead to durable complete remission of these lymphomas.
Study NCT02002897 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Fractional carbon dioxide laser
Description: Fractional carbon dioxide laser (10,600 nm), a session once per month, total of 3 sessions with full clinical evaluation and investigations before and one month after the last session of treatment.
Study NCT02002897 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultraviolet A1 phototherapy (UVA1)
Description: localized UVA1 phototherapy (340-400 nm), low dose irradiation, at a rate of 3 sessions per week , total of 24 sessions with full clinical evaluation and investigations before and after treatment and clinical follow up one month after treatment.
Study NCT01863446 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lighting1
Description: Ocular light exposure to a red wavelength light
Study NCT01863446 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lighting2
Description: Ocular light exposure to a blue/green wavelength light
Study NCT01222494 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Weight Loss
Description: This intervention is a family-based, behavioral weight loss program that has been employed in studies with overweight and obese children, as well as with children who have diabetes. For the proposed study, the program has been modified to fit the needs of disruptive and behaviorally disturbed youth and their families. The modified program includes 16 weeks of weekly visits with a study interventionist, and supplemental phone contacts as needed. Phone contacts will only replace in-person visits if absolutely necessary to achieve the visit.
Study NCT01222494 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Behavioral Weight Loss
Description: This intervention is a family-based, behavioral weight loss program that has been employed in studies with overweight and obese children, as well as with children who have diabetes. For the proposed study, the program has been modified to fit the needs of disruptive and behaviorally disturbed youth and their families. The modified program includes 16 weeks of weekly visits with a study interventionist, and supplemental phone contacts as needed. Phone contacts will only replace in-person visits if absolutely necessary to achieve the visit.
Study NCT01222494 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Diet and Exercise Education
Description: Participants assigned to this arm will receive monthly medically validated, individualized diet and exercise education by a trained research professional.
Study NCT01938534 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Helicobacter pylori eradication
Study NCT01938534 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Helicobacter pylori eradication
Study NCT03362840 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Early Start Denver Model
Description: The ESDM is a manualized comprehensive treatment model for young children (12-48 months). In the preschool based ESDM, learning objectives are guided by the ESDM curriculum checklist, which includes developmental skills in language, play, motor skills, personal independence, imitation and cognition. The objectives are monitored for progress during each session The sessions are conducted according to ESDM principles, and include weekly parent-coaching session, in which parents observe the therapist interact with the child while applying various teaching techniques, and then implement these techniques during the interaction with their child. Additionally, parents get acquainted with the daily objective sheet and are encouraged to work on these objectives at home as well. Finally, in this model, therapist adherence to the ESDM practices are monitored according to the ESDM fidelity rating system
Study NCT03362840 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Eclectic preschool intervention
Description: The eclectic approach consists of a combination of methods from several treatment-models. Individualized educational plans are based on multi-disciplinary assessment, and include objectives in several domains - communication, social-skills, play, emotional adjustment, adaptive daily skills, motor skills and cognition. They are presented to parents at the beginning of the year and are reviewed by the staff three times a year.~Parents attend by-weekly counseling-sessions with a professional in order to receive input regarding their child's progress, and discuss issues concerning their child's functioning. All staff members receive supervision at various intensities. However, these usually do not adhere to a single structure and are not guided by official fidelity criteria.
Study NCT02848118 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: A nasal-oral cannula of capnography
Description: After propofol infusion, the complete induction is defined when capnography shows hypoventilation and bronchoscope is then introduced to patients.
Study NCT02848118 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Observer Assessment of Alertness and Sedation scale
Description: After propofol infusion, the complete induction is defined when OAAS is 3 to 2 (conscious sedation) and bronchoscope is then introduced to patients.
Study NCT04055636 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiography with speckle tracking analysis.
Description: Transthoracic echocardiography with speckle tracking analysis.
Study NCT04055636 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: 48-hour ECG monitoring.
Description: Ambulatory 48-hour electrocardiography monitoring.
Study NCT04055636 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Blood samples analysis.
Description: Analysis of blood samples for biochemistry, biomarkers of myocardial damage, fibrosis and inflammation.
Study NCT04428138 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: In-office vascular visit
Description: Every patient will undergo a complete physical examination in order to detect any clinical or sub clinical vascular disease.
Study NCT04428138 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echo duplex scan of arterial system
Description: Every patient will undergo a complete echo duplex scan in order to detect any morphological or hemodynamic alteration of aorta, carotid arteries and lower limb arteries.
Study NCT03212677 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Ferrous sulfate
Description: Standard-of-care therapy for iron deficiency anaemia
Study NCT03212677 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ferrous sulfate
Description: Standard-of-care therapy for iron deficiency anaemia
Study NCT03212677 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: IHAT
Description: IHAT is a nanoparticle composed of three General Regarded As Safe (GRAS) substances, iron hydroxide, tartaric acid and adipic acid. The particle itself resembles the normal metabolite ferritin, which is a larger polyatomic particle. Like ferritin, IHAT can be absorbed by endocytosis, but dissociates within the enterocyte and is subsequently metabolized as ferrous iron.
Study NCT03212677 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Aspiron
Description: Aspiron is a product of the natural fermentation of Koji (Aspergillus oryzae) in the presence of ferrous sulfate. The iron-rich koji biomass is heated, harvested and dried which results in the inactivation of Koji powder that contains 8-10% iron. Koji (A. oryzae) is widely used for making such foods as soy sauce, tempeh, miso, and for producing food-grade α-amylase, and is considered safe by Joint Food and Agriculture Organization of the United Nations (FAO)/WHO Committee on Food Additives and has been accepted as a GRAS constituent of food.
Study NCT03212677 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Cornstarch
Study NCT02771639 — intervention group
Intervention type: PROCEDURE
Intervention: Hip arthroplasty
Description: Treatment with a hip arthroplasty (semi- or total hip arthroplasty) for a displaced femoral neck fracture
Study NCT01860417 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Allogenic Mesenchymal Stromal Cells
Study NCT01860417 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mepivacaine
Study NCT05298852 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: High resolution computed tomography of the chest
Description: All participants were subjected to High resolution computed tomography of the chest.
Study NCT03779997 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Video-based DOT Application
Description: Participants will be asked to record daily videos of themselves confirming daily ingestion of their buprenorphine. Clinical staff (i.e. physicians, nurses and medical assistants) of patients enrolled in the intervention group will be given training and the opportunity to review medication taking videos.
Study NCT04554433 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Ethanol with Asprin
Description: Group ( A ) which will receive the new protocol will be categorized into sub-groups according to the medical conditions , inclusion criteria , investigations and symptoms .~1. Inhaling alcohol vapor through nostrils .~2. Inhalation of Alcohol vapor driven by Oxygen .~3. Inhalation of Alcohol vapor driven by oxygen in case of ARDS.~4. Ethyl Alcohol infusion into the airway . Investigations will be made before starting the protocol and follow up data will be collected every day .~Follow up test will be done according to the schedule . PCR test will be done according to the duration of each technique to evaluate the final results .
Study NCT04086472 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Clesrovimab
Description: Single dose of clesrovimab administered via IV infusion.
Study NCT04207359 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Creatine
Description: Those randomized to receive creatine (experimental group) will be initially dosed at 20 g/day for 7 days to boost availability of creatine systemically. Thereafter, the dose will be reduced to 5 g/day for maintenance through the duration of the 12-week protocol.
Study NCT02105207 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Lung Ultrasound
Description: Lung ultrasound evaluation is performed after clinical assessment and before chest radiography
Study NCT02105207 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Chest Radiography
Description: Chest Radiography is performed after clinical evaluation without using ultrasound assessment
Study NCT04086472 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo (0.9% sodium chloride, USP sterile saline) administered via IV infusion.
Study NCT04086472 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: RSV-A Memphis 37b
Description: Approximately 4Log10 plaque-forming units (PFU)/mL RSV-A virus inoculation strain Memphis 37b administered via intranasal inoculation.
Study NCT04086472 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: RSV-A Memphis 37b
Description: Approximately 4Log10 plaque-forming units (PFU)/mL RSV-A virus inoculation strain Memphis 37b administered via intranasal inoculation.
Study NCT02624102 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Trial based cognitive therapy
Description: Patients with MDD, in use of antidepressants plus Trial Based Cognitive Therapy
Study NCT02624102 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Activation
Description: Patients with MDD, in use of antidepressants plus Behavioral Activation
Study NCT02624102 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Antidepressants
Description: Patients with MDD, in use of antidepressants (fluoxetine, citalopram, escitalopram, bupropion, etc.) without psychotherapy.
Study NCT00667342 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Bevacizumab
Description: Monoclonal Antibody against vascular endothelial growth factor (VEGF). Given intravenously (IV).
Study NCT00667342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cisplatin
Description: Given IV.
Study NCT00667342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Doxorubicin
Description: Given IV.
Study NCT00667342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: Given IV.
Study NCT00667342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ifosfamide
Description: Given IV.
Study NCT00667342 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: etoposide
Description: Given IV.
Study NCT00667342 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Participants undergo definitive surgery and assessment of histologic response at week 10.
Study NCT00667342 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: Radiation therapy delivered for positive margins or intralesional resections.
Study NCT06129812 — intervention group
Intervention type: DRUG
Intervention: Neoadjuvant treatment
Description: Intravenous gemcitabine-based combination regimens or FOLFIRINOX were included in NAC.
Study NCT03394508 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: ALK diluent 0,3% human albumin
Description: Intralymphatic injection with 0.1 ml. 3 injections with 4-5 weeks interval
Study NCT01107171 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tang-min-ling pills low dosage
Description: low dosage:6g Tang-min-ling pills every time,by 3 times every day for 12 weeks.
Study NCT01107171 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tang-min-ling pills high dosage
Description: high dosage:12g Tang-min-ling pills every time,by 3 times every day for 12 weeks.
Study NCT01107171 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Tang-min-Ling pills analogue 6g,tid,po
Study NCT03726528 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Measurements of left ventricular pressure and volume
Description: Patients with suspected Takotsubo syndrome (typical ballooning in left ventriculography without significant obstructive coronary artery disease that sufficiently explains the contraction abnormalities) will undergo continuous online measurements of left ventricular pressure and volume using conductance catheters. Cardiac magnetic resonance (CMR) imaging will be performed in patients without contraindications for optimized morphological characterization and exclusion of important differential diagnoses.
Study NCT00279435 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: visilizumab
Study NCT02930499 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Hyalomatrix extra-cellular matrix
Description: An exta-cellular matrix made from hyaluronic acid
Study NCT02930499 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Mepilex wound dressing
Description: A siliconized non-adhesive foam wound dressing
Study NCT02044263 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Internet CBT-i SHUTi
Description: Computer program SHUTi is based on the same theoretical model of insomnia and involves the same interventions as ordinary CBT-I: a structured treatment focusing on education, behaviors and cognitions. Specifically, CBT-I usually consists of one or more of the following: psychoeducation about sleep, sleep restriction therapy, stimulus control, relaxation techniques, and challenging beliefs and perception of sleep.
Study NCT02044263 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: face-to-face CBT-i
Study NCT04412941 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Myofunctional exercises
Description: Myofunctional exercises: Respiratory rehabilitation exercises with diaphragmatic breathing, thoracic mobilization exercises and manual pompage techniques, followed by manual trigger point therapy techniques, that were identified by palpation following the guidelines provided by Travell and Simons trigger point manual, the accessory inspiratory muscles like pectoralis minor muscle, scapula elevator muscle, Sternocleidomastoid muscle.~Home oropharyngeal exercises: at every patient will be taught oropharyngeal exercises to perform at home twice a day (the duration of 15 minutes each session) involving in particular exercises for soft palate, tongue, facial and genio-glosso muscle.~The rules of sleep hygiene: a list of behaviours that physiologically promote a good night's sleep.
Study NCT04412941 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: The rules of sleep hygiene
Description: The rules of sleep hygiene: a list of behaviours that physiologically promote a good night's sleep.
Study NCT04412941 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: The rules of sleep hygiene
Description: The rules of sleep hygiene: a list of behaviours that physiologically promote a good night's sleep.
Study NCT04904510 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: INDICAID™ COVID-19 Rapid Antigen Test
Description: The diagnostic assay will be compared to a EUA SARS-CoV-2 assay
Study NCT01956578 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Breathing Exercise Cohort
Description: All patients enrolled will be asked to wear a respiration band and perform a series of breathing exercises.
Study NCT01127256 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: zonisamide
Description: Initial dose was 100mg/day, increased by 100mg. The maximum dose was 600mg/day.
Study NCT01127256 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: carbamazepine
Description: Initial dose was 100mg/day, increased by 200mg every 1 week to 600mg/day. The maximum dose was 1200mg/day.
Study NCT02885545 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Watchman
Description: If the patient is randomized to the Intervention Arm of the study the Watchman device will be implanted into the left atrial appendage of the heart
Study NCT02885545 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Continued therapy with the prescribed oral anticoagulant
Description: If the patient is randomized to the control arm of the study, they will continue taking the oral anticoagulant that has been prescribed (vitamin K antagonist, Apixiban 2.5mg bid or Rivaroxaban 15mg od)
Study NCT00692692 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: DermaMatrix
Description: experimental group with DermaMatrix acellular dermis over tissue expanders in addition to skin/soft tissue and muscle to allow for more natural appearing breast and prevention of complications
Study NCT01479634 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Standard ART
Description: Standard Ugandan 3-drug antiretroviral therapy regimen consistent with current practices
Study NCT01479634 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Study-Provided ART
Description: Study provided drugs:~1. Truvada® (one tablet PO daily of fixed dose combination consisting of tenofovir disoproxyl fumarate \[TDF\] and emtricitabine \[FTC\]) PLUS~2. Efavirenz \[EFV\]
Study NCT03752723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GX-I7
Description: i.m.
Study NCT00692692 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: standard of care tissue expander breast reconstruction surgery after mastectomy
Description: standard of care using skin/soft tissue and muscle coverage of tissue expander for breast reconstruction after mastectomy without acellular dermal matrix
Study NCT03752723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab(KEYTRUDA®)
Description: i.v.
Study NCT03752723 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: i.v.
Study NCT03348761 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: rTMS group
Study NCT02200705 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Ice-Sense3TM/ ProSenseTM