AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02449746 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Plasma Exchange
Description: PLEX is a procedure in which the subject's blood is passed through a medical device which separates out plasma from the other blood components, and replaces the plasma with albumin or plasma or other colloid. PLEX therefore removes circulating pathogenic antibodies, and furthermore therapeutic benefit after PLEX supports an antibody mediated pathogenesis of disease. In PLEX, 200-250 mL plasma per kg body weight is exchanged typically over 7-14 days using 5% albumin as replacement, often at alternate days which increases the amount of immunoglobulin removed due to equilibrium effects. PLEX modality (centrifugation or filtration), type of anticoagulation, and dose scheduling will be determined by local centre practice.
Study NCT02449746 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous immunoglobulin
Description: Active Comparator: Intravenous Immunoglobulin (IVIG) IVIG is a pooled blood product from 3000-100,000 human blood donors with direct immunomodulatory effects.~IVIG will be given at a dose of 2g/kg over 4 days. Dosing at 2g/kg is established in neurological disorders, with limited evidence that lower doses are less effective although adequate dosing studies have not been performed.
Study NCT03834558 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mixed exercise program
Description: A progressive program of high intensity strength and myofascial conditioning will be carried out in 2 non-consecutive weekly sessions (24 weeks). Each session will include:~A) Warm up on a cycle ergometer~B) Strength circuit: 6 exercises will be included to strengthen different muscle groups (2 in the upper extremities, 2 in the trunk and 2 in the lower extremities). 3 sets of 10-15 repetitions until the failure. The load will be set to 70% of 1 maximal resistance.~C) Self-myofascial conditioning: 10 repetitions, in the direction of the fibres of each muscle group, with different materials. 7 muscle groups will be worked (quadriceps, hamstrings, abductors, gluteus, pectoralis, full back and trapezius).~D) At the end, static stretches will be performed
Study NCT01988701 — intervention group
Intervention type: OTHER
Intervention: Ancillary-Correlative
Description: Blood samples are analyzed for activation status of B lymphocytes, T lymphocytes, and NK lymphocytes via flow cytometry, ELISA, ELISPOT, immunoblot, and microarray assays.
Study NCT02190019 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neurostar repetitive transcranial magnetic stimulator
Description: The active procedure will stimulate at 120% motor threshold for 4 seconds at a frequency of 10 Hz, with an inter-train interval of 26 seconds for a total of 3,000 pulses. 10 treatment sessions are given over a two week period.
Study NCT03878433 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Glisodin
Description: 500 mg/day between 12 weeks
Study NCT03878433 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: Placebo group (20 patients) will receive 2 pills of placebo per day + sunscreen for 6 months
Study NCT02870322 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Fruit and Vegetable CSA Prescription
Description: Study Participants will collect and use fruit and vegetable CSA boxes given to them weekly for 10 weeks.
Study NCT02870322 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Bikeshare Prescription
Description: Study participants will use bikeshare for transportation and physical activity for 10 weeks
Study NCT04214652 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDP-126 Gel
Description: IDP-126 Gel applied topically to the face once daily for 12 weeks.
Study NCT03835416 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Foods rich in high quality protein
Description: Along with a weight reduction diet (by instruction), participants will receive high quality protein foods provided to them to include in their daily diet (see study arm description).
Study NCT01699347 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Intracystic injection of OK432 under US guiding
Description: Intracystic injection of OK432 under US guiding
Study NCT00313183 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: pramlintide acetate
Description: single subcutaneous doses of 15mcg and 30mcg
Study NCT00583713 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: BLI-800
Description: BLI-800 oral solution (two doses)
Study NCT00583713 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BLI-800
Description: BLI-800 oral solution (two doses)
Study NCT04214652 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: IDP-126 Vehicle Gel
Description: IDP-126 Vehicle Gel applied topically to the face once daily for 12 weeks.
Study NCT04159883 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: strengthening exercise program for lower-extremity muscles (knee extensor and hip abductor muscles)
Description: Simple progressive strengthening exercise program for lower-extremity muscles (knee extensor and hip abductor muscles), the program has been evident to be significantly effective in improving self-reported knee pain and function. This program included: 1) Isometric quadriceps contraction, 2) Isotonic quadriceps contraction, 3) Isotonic hamstring contraction, 4) Isotonic quadriceps contraction with resistance band, 5), straight leg raising, 6) Side-lying hip abduction, 7) Partial Squats,
Study NCT04159883 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: strengthening exercise program for lower-extremity muscles (knee extensor and hip abductor muscles)
Description: Simple progressive strengthening exercise program for lower-extremity muscles (knee extensor and hip abductor muscles), the program has been evident to be significantly effective in improving self-reported knee pain and function. This program included: 1) Isometric quadriceps contraction, 2) Isotonic quadriceps contraction, 3) Isotonic hamstring contraction, 4) Isotonic quadriceps contraction with resistance band, 5), straight leg raising, 6) Side-lying hip abduction, 7) Partial Squats,
Study NCT04159883 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: My Dear Knee smart phone application
Description: The innovative app has been designed for Android and iPhone Operating System (iOS). The app provides guides with the Arabic language. It designed to be attractive for the older adult and easy to use. the exercises are demonstrated with colorful animated images to make easy to follow by the patients.~The app supports features such as alerts, monitoring system by the physical therapist and remote follow-up. The app provides automatic recording of exercise adherence, including the time and the number of sessions completed for the week in the physical therapist's account.
Study NCT03189979 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity and healthy eating intervention
Description: Using a community-based participatory approach, BGC staff and academic researchers developed intervention components informed by formative studies and based on a social ecological theory framework. Components included healthy eating and physical activity policy implementation, staff training, a challenge/self-monitoring program for healthy behaviors, a peer-coaching program for healthy behaviors, and a social marketing campaign.
Study NCT04453735 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Atorvastatin mylan 40 Mg Oral Tablet
Description: Oral tablet on regular prescription
Study NCT01256216 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Total Knee Replacement with Vanguard Total Knee
Description: Patients indicated for a total knee replacement utilizing the Vanguard Total Knee System.
Study NCT04224688 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rozanolixizumab
Description: Study participants receive rozanolixizumab by subcutaneous infusion at pre-specified time points.
Study NCT04224688 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Study participants receive placebo by subcutaneous infusion at pre-specified time points.
Study NCT01860729 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Anacetrapib
Study NCT02334150 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CSEA (ropivocaine and sufentanil)
Description: Women in the CSEA group received CSEA during labor. An intravenous line was established when the uterine opening measured 1-2 cm. Then sufentanil (5-7 μg) was injected intrathecally. When the visual analogue pain score was 3 or higher, a mixture of ropivocaine (0.143%) and sufentanil (0.3 μg/ml) was continuously infused into the epidural space using an analgesia pump until the cervix was fully dilated. Load capacity was 5 ml. The analgesic plane was controlled under T10.
Study NCT04113967 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Biodanza program
Description: Biodanza is a form of intervention aimed at promoting health and well-being through the promotion of self-expression and self-regulation through interaction through music and dance. The music accompanied by the movement of the body induces some experiences that present the ability to modify the organism itself both at an organic level, as affective-motor and existential. This intervention constitutes a means for the correct development of human qualities, whose purpose is to integrate the potentials of bond, health and harmony, as well as to develop new alternatives for the life of each individual.
Study NCT03863314 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Simulation
Description: Virtual simulation of workplace-related scenarios of pre-recorded videos using the same actors
Study NCT03863314 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: In-person Simulation
Description: In-person simulation of workplace-related scenarios with live actors
Study NCT03871686 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Internet-based Behavioral Activation Intervention
Description: A brief Internet-based behavioral activation intervention consisting of 4 sessions.
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Worsening of olfaction from enrollment visit to 6 months
Description: Worsening of olfaction from enrollment visit to 6 months will be evaluated for association with the primary and secondary outcomes
Study NCT02911805 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Aerobic exercise
Description: Stationary bicycle ergometer @ 50-80% of maximal heart rate reserve for 20 minutes to 45 minutes
Study NCT02911805 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Balance exercise
Description: Instructor-led exercises done in a group setting for strengthening, balance, flexibility
Study NCT02664805 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: LEO 124249 ointment
Description: Ointment
Study NCT02664805 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: LEO 124249 ointment vehicle
Description: Ointment vehicle
Study NCT01351220 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational program and FOBT kits
Description: Subjects will participate in a CRC small group educational program and receive FOBT kits from community health advisors who have received a one-time training session.
Study NCT01351220 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Educational program and FOBT kits, and technical assistance
Description: In addition to subjects' receipt of a CRC small group educational program and FOBT kits, leadership training and technical support will be provided to the community health advisors and selected leaders and members of the organization.
Study NCT05172622 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: JP-2266
Description: * Single Ascending Dose: Single administration on Day 1~* Food effect cohort: Single administration on Day 1 of each period~* Multiple Ascending Dose: Repeated administrations from D1 to D15
Study NCT05172622 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: JP-2266 Placebo
Description: * Single Ascending Dose: Single administration on Day 1~* Food effect cohort: Single administration on Day 1 of each period~* Multiple Ascending Dose: Repeated administrations from D1 to D15
Study NCT01924091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapivirine gel
Study NCT01924091 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dapivirine film
Study NCT01860729 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT01606917 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Intensive lifestyle counseling
Description: Both dietary advice and individualized advice on increased regular physical activity
Study NCT04048278 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine Hydrochloride
Description: IV Lidocaine a 1.0 - 1.5 mg/kg loading infusion for perioperative pain control
Study NCT04048278 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Saline Solution for Injection
Description: IV Saline a 1.0 - 1.5 mg/kg loading infusion for perioperative pain control
Study NCT00946140 — intervention group
Intervention type: PROCEDURE
Intervention: DCE-MRI scans
Description: Initially you will be given safety information about MRI scans and a questionnaire to determine your compatibility with the MRI scanner. For each patient, DCE-MRI data sets will be acquired three times - at baseline just prior to the start of the drug therapy, within 24-48 hours of the start of the therapy, and within 6-8 weeks of the start of the therapy.
Study NCT03002467 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PESI score
Study NCT00028145 — intervention group
Intervention type: BEHAVIORAL
Intervention: Adherence assessment
Description: Adherence will be assessed using questionnaires at all study visits.
Study NCT01608022 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF804
Description: 45 mg p.o. daily and continuously (28-day treatment as one treatment cycle)
Study NCT03278119 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: PET Scan and nocturnal polysomnography
Description: Amyloid PET scans will be used to assess amyloid burden in the brain, and nocturnal polysomnography will be used to assess sleep and cardiopulmonary variables
Study NCT02322853 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Tamoxifen
Description: hormonotherapy
Study NCT02322853 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamoxifen
Description: hormonotherapy
Study NCT02322853 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ralimetinib (LY2228820 dimesylate)
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Worsening of taste from enrollment visit to 6 months
Description: Worsening of taste from enrollment visit to 6 months will be evaluated for association with the primary and secondary outcomes
Study NCT01291485 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Life Steps for Medication Adherence
Description: The intervention was adapted into an electronic version of the empirically supported Life Steps intervention for HIV medication adherence. Education about HIV and medication adherence, motivational interviewing, cognitive behavioral techniques, and problem-solving strategies to improve medication adherence and clinical outcomes in people living with HIV were also included in the intervention.
Study NCT04769180 — intervention group
Intervention type: OTHER
Intervention: Evaluation of extraintestinal manifestations
Description: The researchers evaluated the prevalence and kind of extraintestinal symptoms in NCWS patients and the possible relationship between the clinical, serological, genetic and histological characteristics of the NCWS patients and the number and kind of extraintestinal manifestations, using, as control groups, CD and IBS patients.
Study NCT03756493 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Periodontal Surgery with OFD+ABG+L-PRF
Description: Patients will be treated by periodontal surgical flaps with the addition of L-PRF+ Autogenous Bone Graft filling material.
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Serum Zinc
Description: Serum zinc will be evaluated for association with taste and/or smell impairment
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Chronic rhinosinusitis
Description: Chronic rhinosinusitis will be evaluated for association with smell impairment
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Dialysis adequacy
Description: Dialysis adequacy will be evaluated for association with taste and/or smell impairment
Study NCT03043144 — intervention group
Intervention type: OTHER
Intervention: Decayed missing filled teeth index (DMFT)
Description: DMFT will be evaluated for association with taste impairment
Study NCT03002597 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: BrainPort V200 Device
Description: To see if the device can be used in a pediatric population by measuring the subjects' improvement over baseline in any of the following areas: light detection, light localization, movement perception, and standardized object recognition tasks after use of the BrainPort.
Study NCT01646359 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 1.Esophageal doppler monitor
Description: 1.Esophageal doppler monitor (CARDIO Q®, DELTEX MEDICAL. Brighton, U. K.)-inserted into the esophagus and positioned approximately 35-40 cm from the teeth. The position of OED prove was confirmed by continuously measuring blood flow velocity in the descending thoracic aorta and focused to find the optimum peak velocity and waveform signal.
Study NCT01646359 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 2. philips Intelivue MP70 monitors
Description: 2.philips Intelivue MP70 monitors (Intellivue MP70, philips medical Systems, Suresnes, France) -a radial arterial cannula was inserted and arterial pressure waveforms were monitored through Philips Intelivue MP70 monitors. In the monitor, PPVauto was displayed in real-time. It based on automatic detection algorithms, kernel smoothing, and rank-order filters.
Study NCT02532348 — intervention group
Intervention type: OTHER
Intervention: Blood samples
Description: Blood samples
Study NCT02870725 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: CBT Individual Psychotherapy
Description: The 4-session CBT treatment will include receipt of a manualized cognitive behavioral intervention, delivered individually, to treat the depression symptoms (e.g. cognitive restructuring, behavioral activation) and teach adaptive coping strategies to manage their depression. Ideally, the intervention will also positively affect their chronic headaches (i.e. reduction of headache frequency, severity and level of disability). Each session is approximately 60 minutes with specific, reflective and guided activities related to a specific module within the intervention.
Study NCT02764541 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Letrozole
Study NCT02764541 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Tamoxifen
Study NCT02764541 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Palbociclib
Study NCT02764541 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Endocrine Therapy
Study NCT00360997 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Conventional UK physical therapy
Study NCT01990261 — intervention group
Intervention type: DRUG
Intervention: Erlotinib
Description: Erlotinib at a dose determined by the investigator, guided by the recommendation in the Summary of Product Characteristics.
Study NCT02853760 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: walking
Study NCT02853760 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: walking
Study NCT02853760 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Treadmill
Study NCT04452890 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Sonourethrography
Description: Ultrasound of the urethra.
Study NCT00360997 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Con UK PT + Mobilisation & tactile stimulation (MTS)
Description: Con UK PT + Mobilisation \& Tactile Stimulation (MTS) which is further randomised to 30, 60 or 120 mins/day
Study NCT04355104 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: A one hour educational session per week for 4 weeks. In a total of 4 sessions of education, the content based on LBP Clinical Practice Guidelines which recommended that education and counseling strategies for patients with low back pain.~Education session will be through video lecturing as a motivated tool of education for all subject who are in experimental group, this video will repeated the same in every educational session and will be sent for all participants.~The neuroscience education will be by the therapist using interactive slide show and hand-drawing images.~In addition to the education video, slide show, we will specify the education for every patient to give him all that he need, questions and details, mention his case on real spine to explore it and to determine the expected goal from what he need and what we have.
Study NCT04355104 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Standard physical therapy
Description: Two session physical therapy per week for 4 weeks. The physical therapy will be based on patients case.
Study NCT04355104 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard physical therapy
Description: Two session physical therapy per week for 4 weeks. The physical therapy will be based on patients case.
Study NCT03756493 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Periodontal Surgery with OFD+ABG
Description: Patients will be treated by periodontal surgical flaps with the addition of Autogenous Bone Graft filling material.