AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05906654 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sharing History through Active Reminiscence and Photo-imagery (SHARP)
Description: Behavioral intervention to increase physical and social activity. In triads, participants walk 1-mile neighborhood routes three times per week and engage in image-based conversational reminiscence.
Study NCT02297425 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-06459988
Description: The study will evaluate PF-06459988 PO (tablets) continuous daily dosing in 21 day cycles. The starting dose for PF-06459988 will be 50 mg PO daily. The escalation/de-escalation rules will follow the modified toxicity probability interval method with adjustments using the DLT rate and maximum size per dose level of 10 patients
Study NCT02670421 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Face to Face Heart SMART Program
Description: The Heart SMART stress management program survey consists of Perceived Stress Scale (PSS), Brief Resilience Scale (BRS), Patient Health Questionnaire (PHQ - 9) and Generalized Anxiety Disorder (GAD - 7), followed by email communication every three weeks.
Study NCT02670421 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: On-line Heart SMART Program
Description: The Heart SMART stress management program survey consists of PSS (Perceived Stress Scale), BRS (Brief Resilience Scale), PHQ-9 (Patient Health Questionnaire) and GAD-7 (Generalized Anxiety Disorder) taken on-line in twelve, 10 minutes sessions.
Study NCT02670421 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Mayo Clinic Guide to Stress Free Living
Description: All subjects will be provided with a copy of the book entitled Mayo Clinic Guide to Stress Free Living and encouraged to read it over the twelve week study period.
Study NCT03461783 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Zorflex Activated Carbon Dressing
Description: Antimicrobial dressing
Study NCT03461783 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Standard of Care
Description: foam, calcium alginate, hydrogel, or compressive dressings
Study NCT02604823 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Peginterferon alfa-2a
Description: Peginterferon alfa-2a will be administered at a dose of 180 mcg subcutaneously once weekly for 48 weeks.
Study NCT00135707 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for Vitamin C and Vitamin E
Description: Placebo two capsules daily between randomization (at 9 - 16 weeks gestation) up to delivery.
Study NCT00922974 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: External beam radiation therapy
Description: Single fraction dose of 8 Gy external beam radiation therapy
Study NCT00922974 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiosurgery/SBRT
Description: Single fraction dose image-guided radiosurgery / stereotactic body radiotherapy (SBRT). The phase II component uses 16 Gy. The phase III component allows 16 or 18 Gy as preferred by the treating physician.
Study NCT03260764 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: short term Multifocal Contact Lenses
Description: wearing Multifocal Contact Lenses for one week
Study NCT03260764 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: short term Multifocal Contact Lenses
Description: wearing Multifocal Contact Lenses for one week
Study NCT03260764 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: short term Bifocal Spectacles
Description: wearing Bifocal Spectacles for one week
Study NCT03260764 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: short term Bifocal Spectacles
Description: wearing Bifocal Spectacles for one week
Study NCT01871688 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: pelvic floor rehabilitation program with neuromodulation
Description: pelvic floor rehabilitation program with neuromodulation
Study NCT03924700 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Biportal endoscopy
Description: Biportal endoscopic spine surgery (BESS)
Study NCT03924700 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Microdiscectomy
Description: Using microscope for discectomy
Study NCT01067846 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Seromycin (D-cycloserine, DCS)
Description: 250 mg DCS once weekly for 4 weeks prior to the initiation of a Computerized Cognitive Behavioral Therapy (CBT) session for drug relapse intervention.
Study NCT03260764 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: long term Multifocal Contact Lenses
Description: wearing Multifocal Contact Lenses for one year
Study NCT01067846 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo identical looking to the 250 mg DCS once weekly for 4 weeks prior to the initiation of a Computerized Cognitive Behavioral Therapy (CBT) session for drug relapse intervention.
Study NCT01067846 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Computerized Cognitive Behavioral Therapy
Description: All participants received Computerized Cognitive Behavioral Therapy sessions 3 times per week for 4 weeks as a drug relapse intervention.
Study NCT01067846 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Computerized Cognitive Behavioral Therapy
Description: All participants received Computerized Cognitive Behavioral Therapy sessions 3 times per week for 4 weeks as a drug relapse intervention.
Study NCT01396772 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: PREPARE education program
Description: PREPARE stands for Prediabetes Research and Education Promoting Activity and Responsible Eating and is a 6-month community-based prediabetes lifestyle and behaviour change intervention program. It includes a series of six interactive education sessions of two hours each on healthy eating and physical activity.
Study NCT01396772 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: standard of care presentation
Description: A one-time 2-hour group prediabetes education session, offered as the standard for individuals referred for prediabetes in London, Ontario (Canada)
Study NCT01791972 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albuterol Spiromax
Description: Albuterol Spiromax is an inhalation-driven, multi-dose dry powder inhaler (DPI) containing a blend of albuterol sulfate with alpha-lactose monohydrate. Each actuation represents a dose of 90 mcg of albuterol sulfate. Participants received one dose of two inhalations (180 mcg).
Study NCT01791972 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo Spiromax
Description: Placebo Spiromax is an inhalation-driven, multi-dose dry powder inhaler (DPI) delivering placebo to match the experimental drug. Participants received one dose of two inhalations.
Study NCT01422473 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: EnSeal Trio Tissue Sealing Device
Description: For surgery in ligating and dividing vascular tissue during abdominal surgery.
Study NCT04047173 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: stereotactic body radiotherapy (SBRT)
Description: Radiotherapy dose is 36-54 Gy, irradiated in 3 times, every other day, completed within 1 week.
Study NCT04047173 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Radiofrequency ablation (RFA)
Description: RFA with a safe margin, RFA again if residual, no more than 2 times.
Study NCT03508401 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Passive leg raising (PLR)
Description: PLR is a test that predicts whether cardiac output will increase with volume expansion. By transferring a volume of around 300 mL of venous blood from the lower body toward the right heart, PLR mimics a fluid challenge. However, no fluid is infused and the hemodynamic effects are rapidly reversible, thereby avoiding the risks of fluid overload.~PLR starts from the semi-recumbent and not the supine position. PLR is performed by adjusting the bed and not by manually raising the patient's legs
Study NCT03508401 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Echo-Doppler measurements
Description: Echo-Doppler measurements are performed with Vivid S6 model (GE Healthcare France, Lyon, France). All measurements are recorded at the end of expiration. Echo-Doppler measurements are performed in the upper part of the SVC, approximately 1 to 2 cm below the brachiocephalic vein. From this view, pulse Doppler is performed. Pulse Doppler waves obtained in the SVC are used to obtain velocity time integrals (VTI). Expiratory VTI is named VTImax and inspiratory VTI is named VTImin. These values will allow the calculation of Respiratory variations of the superior vena cava flow (ΔSVCf).~ΔSVCf is calculated as (VTImax- VTImin )/(1/2(VTImax+ VTImin)).
Study NCT02193490 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: DNase
Description: DNase 0.1% eye drops four times a day for 8 weeks
Study NCT02193490 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vehicle
Description: Drug vehicle eye drops four times a day for 8 weeks
Study NCT04332055 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: ERVIN
Description: ERVIN is state of the art for IT systems, which uses artificial intelligence (AI) and real-time patient-specific PRO data to support patients and doctors in clinical decision-making. The system is designed for surgical OA treatment of knee and hip replacement, and can be used to predict outcome scores for the actual choice OA patients face in the patient trajectory; to choose surgery or not.
Study NCT04197375 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Thermal stress and performance using a pre-cooling protocol
Description: One hour before a tennis match, participants were wearing a Cooling Cap (WElkins Sideline Cooling System, SCS) for 45 minutes. During the tennis match the following variables were monitored: heart rate, core temperature, skin temperature, thermal sensation and comfort, rating of perceived exertion and hydration status.
Study NCT04197375 — intervention group
Intervention type: BIOLOGICAL
Group type: SHAM_COMPARATOR
Intervention: Thermal stress and performance without a pre-cooling protocol
Description: During a tennis match the following variables were monitored: heart rate, core temperature, skin temperature, thermal sensation and comfort, rating of perceived exertion and hydration status.
Study NCT02002377 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aflibercept
Description: Aflibercept 2 mg (0.05 mL or 50 microliters) will be administered by intravitreal injection every 4 weeks for the first 8 weeks, followed by 2 mg (0.05 mL) via intravitreal injection once every 8 weeks for 36 weeks
Study NCT01250795 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HAI-05 Influenza Vaccine
Description: injection, vaccine, twice every 3 weeks
Study NCT01250795 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Saline
Study NCT05038605 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Topical metronidazole
Description: Topical application of metronidazole cream on the anal verge every 8 hours after surgery
Study NCT05038605 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: oral metronidazole
Description: Patients received oral metronidazole 500 mg tablets every 8 hours after surgery
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam Injectable Solution
Description: intravenous
Study NCT03534895 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Normal saline
Description: intravenous
Study NCT03534895 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Normal saline
Description: intravenous
Study NCT03534895 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Spinal anesthesia
Description: 8mg of heavy bupivacaine 0.5% injected in the subarachnoid space, during lateral decubitus
Study NCT03534895 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Spinal anesthesia
Description: 8mg of heavy bupivacaine 0.5% injected in the subarachnoid space, during lateral decubitus
Study NCT03534895 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Surgery
Description: Open inguinal hernia repair, varicose vein stripping, knee arthroscopy or hallux valgus surgery
Study NCT03534895 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgery
Description: Open inguinal hernia repair, varicose vein stripping, knee arthroscopy or hallux valgus surgery
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Postoperative analgesia
Description: IV acetaminophen 1g + IV ketorolac 30mg
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Postoperative analgesia
Description: IV acetaminophen 1g + IV ketorolac 30mg
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Rescue analgesia
Description: Tramadol 2mg/Kg IV in 100mL of normal saline, if pain NRS>3.
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rescue analgesia
Description: Tramadol 2mg/Kg IV in 100mL of normal saline, if pain NRS>3.
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Wound infiltration
Description: Wound infiltration with 10mL of ropivacaine 0.75%, in open inguinal hernia repair
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Wound infiltration
Description: Wound infiltration with 10mL of ropivacaine 0.75%, in open inguinal hernia repair
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Analgesia at home
Description: Oral acetaminophen 1g 6/6h + ibuprofen 400mg 8/8h (+ rescue analgesia with tramadol 50mg 6/6h)
Study NCT03534895 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Analgesia at home
Description: Oral acetaminophen 1g 6/6h + ibuprofen 400mg 8/8h (+ rescue analgesia with tramadol 50mg 6/6h)
Study NCT03066882 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: NCD
Description: negative calorie diet
Study NCT03066882 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: LCD
Description: low calorie diet
Study NCT03230604 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Filtek Bulk Fill Composite and Tetric N Ceram Bulk Fill Composite
Description: Restorative cavities one, two and five with material Filtek Bulk Fill Composite
Study NCT03230604 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Z 350 Xt Composite
Description: Restorative cavities one, two and five with material Z 350 XT Composite
Study NCT02214875 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: CQI/BTS
Description: Application of CQI/BTS interventions through employing rapid structured cycles of data collection, testing of solutions and review of changes will be implemented. At each site a Quality Improvement Team (QIT) will be established from among the facility staff. Local Government and State level QI teams will provide oversight function of the health facilities' QI initiatives. BTS as a collaborative learning approach will be conducted quarterly in each study state at a central location with participants from the intervention sites. The sessions will provide opportunity for teams to learn from each other and to adapt and implement changes using the Plan-Do-Study-Act (PDSA) model.
Study NCT02214875 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Control
Description: Facilities in control will continue will routine unstructured, irregular continuous quality improvement. Break Through Collaborative will not be applied to the control facilities.
Study NCT00277095 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ProACT (Adjustable Continence Therapy)
Description: Implantable device to reduce urinary stress incontinence
Study NCT01930097 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: 14 hours intervention
Description: Subjects will be admitted at the IRCM at 6:30. Subjects will be asked to fast from midnight. At 8:00, a standardized (50g CHO for males; 30g CHO for females) meal will be served. At 12:00, a standardized (120g CHO for males; 90g CHO for females) meal will be served. At 17:00, a standardized (70g CHO for males; 50g CHO for females) meal will be served. Between meals, patients will be allowed to do sedentary activities (reading, watching television, and playing video games, etc).
Study NCT03568643 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Azithromycin
Description: Children enrolled in the trial and randomized to azithromycin will receive a single directly observed dose of oral azithromycin at 20 mg/kg up to the maximum adult dose of 1 g. Oral azithromycin will be administered at the time of enrollment. Enrolled children will also receive RUTF.
Study NCT03568643 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amoxicillin
Description: Children enrolled in the trial and randomized to azithromycin will receive a 7-day course of oral amoxcillin given in twice-daily doses of 50-100 mg/kg, per the Burkina Faso guidelines for the management of severe acute malnutrition. The first dose will be administered at the time of enrollment and the remaining dose will be administered by the caregiver at home. Enrolled children will also receive RUTF.
Study NCT03541681 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Glucocorticoid Injections
Description: 1 ml Dexamethasone + 0,5 ml Bupivacain
Study NCT03541681 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Anesthetic Injections
Description: 0,5 ml Bupivacain
Study NCT02465151 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Protein-based beverage
Description: protein-based beverage
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: educational intervention
Description: Undergo Bilingual Breast Cancer Educational Intervention
Study NCT01043003 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: quality-of-life assessment
Description: Ancillary studies
Study NCT01043003 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: quality-of-life assessment
Description: Ancillary studies
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Questionnaire Administration
Description: Ancillary studies
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: psychosocial support for caregiver
Description: Support for caregiver
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: psychosocial support for caregiver
Description: Support for caregiver
Study NCT01043003 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: assessment of therapy complications
Description: Ancillary study
Study NCT01043003 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: assessment of therapy complications
Description: Ancillary study
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: informational intervention
Description: Undergo evaluation sessions
Study NCT01043003 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: informational intervention
Description: Undergo evaluation sessions
Study NCT04036851 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Peer support intervention
Description: Peer support groups will meet monthly for the duration of follow-up, with separate groups for pregnant and postpartum women. Groups will be facilitated by women who are living with HIV and have experience of PMTCT services in this setting. Group sessions will include brief information and a structured discussion about a relevant topic, followed by opportunities for unstructured discussion.
Study NCT02593799 — intervention group
Intervention type: PROCEDURE
Intervention: Endoscopy
Description: Upper gastrointestinal endoscopy to evaluate the presence of any grade varices and high-risk varices.
Study NCT00955890 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexrazoxane hydrochloride
Description: pink power 250mg/bottle DEX:EPI,10:1 every 3 weeks
Study NCT00955890 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexrazoxane hydrochloride
Description: pink powder 250mg/bottle DEX:EPI,15:1 every 3 weeks
Study NCT03682185 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Attention-Control Condition
Description: This condition will contain no active elements beyond its nonspecific components, and no theoretical basis to support an effect on CRDs. The attention-control group will also involve 4 in-home visits and 4 brief telephone education sessions. The attention control group will receive printed educational and training materials from the Alzheimer's Association and the NIH on home modification, health promotion, talking to your doctor, and advanced care planning that coincide with session content.
Study NCT03682185 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Timed Activity Intervention
Description: The timed activity group will involve 4 in-home visits and 4 brief telephone education sessions provided over 4 weeks. The timed activity intervention provides activities delivered at specific times in the daily cycle. The in-home sessions are spaced weekly so that the participants can have the opportunity to practice the activity with the interventionist and then on their own. During each session, the interventionist will reinforce activity use, review problem-solving approaches, and provide education.