AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02583737 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: lyophilized bone allograft
Description: sinus lifting filling procedure employing lyophilized bone allograft from tissue bone bank.
Study NCT01386359 — intervention group
Intervention type: DRUG
Intervention: No Intervention
Description: No Intervention. Subjects are previously treated with Nulojix (belatacept)
Study NCT02282943 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Laser
Description: Vapourisation/excision of endometriosis AFS stages I-III using CO2 laser
Study NCT02282943 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Harmonic scalpel
Description: Excision of endometriosis using Harmonic scalpel
Study NCT00088374 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 17 allylamino-17-demethoxygeldanamycin
Description: 17 allylamino-17-demethoxygeldanamycin (17 AAG) given intravenously at a dose of 300 mg/m2 on days 1,8 and 15 of 28 day cycles.
Study NCT00088374 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18 FDG (Fludeoxyglucose 18F)
Description: 18FDG PET performed at baseline and 12 weeks after treatment. At each timepoint participants can receive 250mCi 0-15 water and 15 mCi F18-FDG.
Study NCT00088374 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [15-O] H2O
Description: \[15-0\] H20 performed at baseline and 12 weeks after treatment. At each time point participants can receive 250mCi 0-15 water and 15 mCi F18-FDG. The water scans were done as several intravenous injections for several scans but not over a total of 250 mCi.
Study NCT00088374 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: EPL diluent
Description: 17AAG is formulated with this diluent. Supplied in a 50 mL flint vial containing 48 mL of 2% egg phospholipids, and 5% dextrose in Water for Injection, USP. Patients with a history of serious allergic reactions to eggs should not receive this agent.
Study NCT03730116 — intervention group
Intervention type: DRUG
Intervention: bisoprolol/perindopril FDC
Description: the first and only single-pill combination of beta-blocker and ACE inhibitor
Study NCT02457637 — intervention group
Intervention type: OTHER
Intervention: Standary therapy
Description: Standary therapy for chronic liver disease with ALI and/or AD
Study NCT00987038 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: PF-04171327 25 mg
Description: One 25 mg tablet administered once a day for 15 days
Study NCT00987038 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Midazolam 2 mg
Description: Midazolam oral syrup 2mg dose administered once on Day 1 and once on Day 15
Study NCT04017260 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: open and closed approach
Description: The patients were hospitalized, and the site of the operation was shaved on the day of the surgery. All Patients were operated on under spinal anesthesia. Antibiotic was administered to all patients as prophylaxis 60 minutes prior to the surgery. An adhesive tape was used to part the buttocks. The patients were placed in the jack-knife position. (Fig. 1). Methylene blue was injected without pressure through the external opening to delineate the sinus. The operation site was cleaned with 10% povidone-iodine. All sinus tracts were resected en bloc via elliptical incision down to presacral fascia with meticulous hemostasis.~Group A:The wound was closed with 0 polypropylene u-shaped sutures .
Study NCT04017260 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rhomboid flap technique
Description: The patients were hospitalized, and the site of the operation was shaved on the day of the surgery. All Patients were operated on under spinal anesthesia. Antibiotic was administered to all patients as prophylaxis 60 minutes prior to the surgery. An adhesive tape was used to part the buttocks. The patients were placed in the jack-knife position. (Fig. 1). Methylene blue was injected without pressure through the external opening to delineate the sinus. The operation site was cleaned with 10% povidone-iodine. All sinus tracts were resected en bloc via elliptical incision down to presacral fascia with meticulous hemostasis.Rhomboid flap technique: involve closure of the defect after excision of all sinuses with Rhomboid flap of skin and subcutaneous tissue
Study NCT04017260 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Karydakis technique
Description: The patients were hospitalized, and the site of the operation was shaved on the day of the surgery. All Patients were operated on under spinal anesthesia. Antibiotic was administered to all patients as prophylaxis 60 minutes prior to the surgery. An adhesive tape was used to part the buttocks. The patients were placed in the jack-knife position. (Fig. 1). Methylene blue was injected without pressure through the external opening to delineate the sinus. The operation site was cleaned with 10% povidone-iodine. All sinus tracts were resected en bloc via elliptical incision down to presacral fascia with meticulous hemostasis.the long axis of the ellipse is parallel to the midline and 2cm from it.undercutting incision is made along the whole length 1cm below the skin surface then unrolling the flap over the midline.
Study NCT04017260 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: open technique
Description: The patients were hospitalized, and the site of the operation was shaved on the day of the surgery. All Patients were operated on under spinal anesthesia. Antibiotic was administered to all patients as prophylaxis 60 minutes prior to the surgery. An adhesive tape was used to part the buttocks. The patients were placed in the jack-knife position. (Fig. 1). Methylene blue was injected without pressure through the external opening to delineate the sinus. The operation site was cleaned with 10% povidone-iodine. All sinus tracts were resected en bloc via elliptical incision down to presacral fascia with meticulous hemostasis.Open procedure involved a wide excision of the pilonidal sinus tract and healing by secondary intention.
Study NCT01201239 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: raltegravir
Description: RAL 400 mg twice daily plus OBT (optimized background therapy) for 48 weeks
Study NCT02604277 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Interpersonal and Social Rhythm Therapy (ISRT)
Description: Interpersonal and Social Rhythm Therapy (ISRT) will be given once a week over a six week period for 55-60 minutes. ISRT emphasizes identifying and maintaining a regular routine in daily life. It includes addressing sleep and solving interpersonal concerns and conflicts by focusing on daily routine.
Study NCT02604277 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Bipolar-Specific Cognitive Behavioral Therapy (CBT)
Description: Bipolar-Specific Cognitive Behavioral Therapy (CBT) will be given once a week over a six week period for 55-60 minutes.The therapy is directly focused on eliminating or managing specific problems experienced by people with Bipolar Disorder. As part of this intervention, participant's maladaptive thoughts, behaviors and emotions are identified followed by learning how to challenge negative thoughts and reframing into positive, more adaptive thoughts. Additionally, the intervention involves enhancing the participant's coping skills and the ability to view a situation more objectively.
Study NCT02604277 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mindfulness-Based Stress Reduction (MBSR)
Description: Mindfulness-Based Stress Reduction (MBSR) will be given once a week over a six week period for 55-60 minutes. MBSR is a structured intervention that utilizes mindfulness meditation to reduce suffering associated with physical and psychiatric illnesses. MBSR is nonreligious in nature and aims to encourage an enhanced awareness of moment-to-moment experience of noticeable mental processes.
Study NCT02604277 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Psycho-education & Understanding Bipolar Medications Therapy
Description: Psycho-education \& Understanding Bipolar Medications Therapy will be given once a week over a six week period for 55-60 minutes. Psycho-education \& Understanding Bipolar Medications Therapy aims to provide psycho-education about Bipolar Depression as well as provide a platform for participants to address concerns about managing their illness. Issues such as managing symptoms, reducing relapses and hospitalizations as well as maintaining gains will be discussed
Study NCT04503278 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CLDN6 CAR-T
Description: administered as an intravenous (i.v.) infusion.
Study NCT04503278 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CLDN6 uRNA-LPX/CLDN6 modRNA-LPX
Description: administered as an i.v. injection at protocol-specified intervals.
Study NCT04499443 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GST-HG131 tablets
Description: This trial includes single-dose studies and multiple-dose studies, The single-dose study included six dose groups of 10 mg, 30 mg, 60 mg, 100 mg, 150 mg, 200 mg, 250mg and 300 mg. Based on the results of a single dose, select 1 to 3 doses to conduct multiple dose studies.
Study NCT04499443 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: This trial includes single-dose studies and multiple-dose studies, The single-dose study included six dose groups of 10 mg, 30 mg, 60 mg, 100 mg, 150 mg, 200 mg, 250mg and 300 mg. Based on the results of a single dose, select 1 to 3 doses to conduct multiple dose studies.
Study NCT03705728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Propofol
Description: Propofol will be automatically administered according to the EasyTIVA device algorythm to maintain the BIS value within the 40-60 interval
Study NCT03705728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sevoflurane
Description: Sevoflurane will be manually administered to maintain the BIS value within the 40-60 interval
Study NCT03705728 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Remifentanil automatic
Description: Remifentanil will be automatically administered according to the EasyTIVA device algorythm to maintain the BIS value within the 40-60 interval
Study NCT03705728 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Remifentanil manual
Description: Remifentanil will be manually administered to maintain the BIS value within the 40-60 interval
Study NCT00872807 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle counseling in groups
Description: The activity school in Finnmark. Lifestyle counseling (physical activity and dietary modification) in groups both at the hospital and in their own municipality.~They meet a multidisciplinary team, receive organized physical activity in the municipality and are invited to a 3 days camp after 4-6 months.
Study NCT00872807 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Individual intervention
Description: Conventional lifestyle counseling individually by single health professionals, both in hospital and in municipality.
Study NCT00872807 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Individual intervention
Description: Conventional lifestyle counseling individually by single health professionals, both in hospital and in municipality.
Study NCT02385630 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Standardized 400kcal semi-liquid meal
Description: Used to assess post-prandial gut hormone response pre-operatively and at 10 days, 4 weeks, 6 months and 12 months post-operatively.
Study NCT04539210 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Electric Welded Metal Framework
Description: Screw-retained Maxillary Complete Denture With Electric Welded Metal Framework
Study NCT02358642 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Angiotensin converting enzyme inhibitor (Lisinopril)
Study NCT02358642 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT01745770 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mesalazine - TID 1000 mg
Study NCT01745770 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Mesalazine - TID 2x 500 mg
Study NCT03861754 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Lifestyle modification
Study NCT02408471 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Ascension® MCP Finger Implant
Description: Patients who meet inclusion/ exclusion criteria are treated with the Ascension® MCP.
Study NCT02594306 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Emotional pictures stimulation system
Description: Emotional pictures stimulation system is component of neutral and drug-related images.
Study NCT02594306 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Emotional pictures stimulation system
Description: Emotional pictures stimulation system is component of neutral and drug-related images.
Study NCT02594306 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Deep brain stimulation
Description: Deep brain stimulation of bilateral NAc/ALIC
Study NCT02594306 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: adjacent contact stimulation
Description: The electrode of deep brain stimulation has four contacts.We stimulate one contact,and record the local field potential of other contacts.
Study NCT02594306 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: microelectrode
Description: We put the microelectrodes into bilateral nucleus accumbens and anterior limb of the internal capsule,to record the waveform of bilateral NAc/ALIC.
Study NCT03685266 — intervention group
Intervention type: OTHER
Intervention: Observation
Description: There are no specific interventions in this study; it is observational only. One could argue that the act of observing the participants may change their behavior (the Hawthorne effect).
Study NCT01740375 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: esophagectomy
Description: esophagectomy
Study NCT03254420 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Calypso beacon implant
Description: Calypso beacon implant before radiotherapy
Study NCT03254420 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: moderate hypofractionation Radiotherapy
Description: moderate hypofractionation Radiotherapy
Study NCT03254420 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: moderate hypofractionation Radiotherapy
Description: moderate hypofractionation Radiotherapy
Study NCT03205462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorothyazinone 300 mg
Description: Fluorothyazinone in a dosage of 300 mg (1 tablet)
Study NCT03205462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorothyazinone 600 mg
Description: Fluorothyazinone in a dosage of 600 mg (2 tablets) is received per os (oral administration) as a single dose
Study NCT03205462 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fluorothyazinone 3900 mg
Description: The total dose of Fluorothyazinone per treatment course is 3900 mg.
Study NCT03169985 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rosuvastatin 10 mg plus ezetimibe 10 mg orally once a day
Description: After the initial 12 months, randomized intervention will be stopped and then this arm will be received either usual dose rosuvastatin plus ezetimibe or high-dose rosuvastatin during the next 24 months by clinical judgement.
Study NCT03169985 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Rosuvastatin 20 mg orally once a day
Description: After the initial 12 months, randomized intervention will be stopped and then this arm will be received either usual dose rosuvastatin plus ezetimibe or high-dose rosuvastatin during the next 24 months based by clinical judgement.
Study NCT00858858 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ursodeoxycholic Acid
Description: 8 weeks of oral UDCA treatment 10 mg/kg qd
Study NCT01547455 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atorvastatin(Lipitor)
Description: participants take 80mg Atorvastatin orally 12h before surgery with another 40mg 2h before surgery
Study NCT01547455 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Participants randomized to Control arm take 80mg placebo 12h before surgery with another 40mg 2h before surgery
Study NCT00264238 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Memantine
Description: pharmacological dosing of memantine as adjunctive therapy for treatment-resistant obsessive-compulsive disorder
Study NCT06491758 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PENFS- Percutaneous Electrical Nerve Field Stimulation
Description: PENFS- Percutaneous Electrical Nerve Field Stimulation (PENFS) has been shown to be an effective treatment for abdominal pain in adolescent patients with irritable bowel syndrome (1). The mechanism is unclear. PENFS is thought to stimulate branches of several cranial nerves in the external ear (V, VII, IX and X) that project to the brainstem. However, the mechanism responsible for the clinical effect is unclear and speculative. We propose to determine whether PENFS 1) stimulates the vagus nerve and produces measurable vagus nerve compound actions potentials, 2) causes changes in parasympathetic and sympathetic nerve activity, and 3) produces changes in the human electrogastrogram (EGG).
Study NCT01806779 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Chantix
Study NCT06491758 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: wrist worn Corsano Cardio Watch 287-2B)-
Description: Use of wearable device (wrist worn Corsano Cardio Watch 287-2B)- It will be used in the next phase to gather critical data that describe the study participant physiology during their normal daily activities (Fig 1A). Wearable-sensor derived biometrics that describe changes in heart rate, respiration rate, blood oxygen saturation, noninvasive blood pressure, physical activity, electrodermal activity (EDA), and sleep will be paired with daily symptom diaries and weekly surveys to assess quality of life and autonomic dysfunction (Fig 1B). The aim is to capture the nature, type, frequency, and severity of common EDS symptoms, such as posture-related tachycardic or hypotensive events, sleep disturbances, musculoskeletal pain, severe fatigue, and gastrointestinal distress.
Study NCT01806779 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Zyban
Study NCT01806779 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotine patches
Description: All participants will receive 21 mg/24 h dose nicotine (nic.) patches for 1 week.
Study NCT06491758 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Gastroelectric Stimulator (GES)
Description: This procedure is where patients with GES already implanted will have EKG readings and blood draws taken for baseline, experimental (stimulator turned off) and Recovery (Stimulator turned on) Blood Draws are for obtaining levels of Insulin, C-Peptides and Glucose levels to track changes.
Study NCT00861744 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: GSK Biological's investigational vaccine 209762
Description: Subcutaneous injection, one dose
Study NCT06491758 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: TaVNS (Transcutaneous Auricular Vagal Nerve Stimulation) Device
Description: • Two MRI compatible electrodes will be placed in the auricle of the left ear, fixed by a plastic armature that wraps around the ear. The leads from the electrodes are connected to a stimulator.• Two ECG electrodes are placed on both sides of the neck overlying the area near the carotid artery where the vagus nerve is superficial. This is to measure the vagal action potentials in the neck.• Two ECG electrodes are placed one on each arm and one on the chest for measurement of the electrocardiogram.• Three ECG electrodes are placed on the abdomen in a line parallel to the longitudinal axis of the stomach to record the ECG
Study NCT04897243 — intervention group
Intervention type: DRUG
Intervention: Biktarvy
Description: B/F/TAF (Biktarvy®) is a fixed-dose combination of bictegravir (50 mg), emtricitabine (200 mg), and tenofovir alafenamide (25 mg), administered orally, once daily, without food requirements. Participating patients will receive the medication free of charge.
Study NCT04897243 — intervention group
Intervention type: BEHAVIORAL
Intervention: Patient Experience
Description: To capture and integrate the patient experience, this study will collect patient-reported experience measures, conduct qualitative interviews, and engage patients as well as providers.
Study NCT00861744 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: M-M-R® II (Merck and Co)
Description: Subcutaneous injection, one dose
Study NCT00861744 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Varivax®
Description: Subcutaneous injection, one dose
Study NCT02137798 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Radio-frequency catheter ablation
Description: Radio-frequency atrial fibrillation catheter ablation includes circumferential PV isolation and voltage-map guided substrate modification, which means low voltage zone (amplitude \< o.5 mV) will also be ablated.
Study NCT00861744 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Varivax®
Description: Subcutaneous injection, one dose
Study NCT02137798 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Radio-frequency catheter ablation
Description: Radio-frequency atrial fibrillation catheter ablation includes circumferential PV isolation and voltage-map guided substrate modification, which means low voltage zone (amplitude \< o.5 mV) will also be ablated.
Study NCT02030873 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Virtual simulation training
Description: Virtual simulation training in the Visible Ear Simulator.
Study NCT00359476 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vinflunine
Description: solution for injection, IV, 280/320 mg/m2, every 3 wks, variable duration
Study NCT00861744 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Havrix®
Description: Intramuscular injection, one dose