AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01018394 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: nicotine lozenges
Description: 4 mg nicotine lozenges for a maximum duration of 12 weeks used ad lib - up to 8 nicotine lozenges per day.
Study NCT01018394 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tobacco-free snuff
Description: Tobacco-free snuff used ad lib for a maximum of 12 weeks
Study NCT04113122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Skin biopsy
Description: A 4 mm skin biopsy will be performed at the upper leg of the patient. Before the skin biopsy local anesthesia is applied subcutaneously. In these skin biopsies senescent cells will be detected by p16, p21 and yH2Ax staining. Furthermore, we will measure platinum levels in the skin biopsies.
Study NCT04113122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Skin biopsy
Description: A 4 mm skin biopsy will be performed at the upper leg of the patient. Before the skin biopsy local anesthesia is applied subcutaneously. In these skin biopsies senescent cells will be detected by p16, p21 and yH2Ax staining. Furthermore, we will measure platinum levels in the skin biopsies.
Study NCT04113122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Subcutaneous fat biopsy
Description: An abdominal subcutaneous fat biopsy will be performed 7-10 cm on the right side of the umbilicus. Before the fat biopsy local anesthesia is applied subcutaneously. An amount of 30 mg fat tissue will be collected using needle aspiration.~In these fat biopsies senescent cells will be detected by p16, p21 and yH2Ax staining. Furthermore, we will measure platinum levels (ICP-MS), adipocytokines (leptin, adiponectin, interleukin-6, PAI-1, TNF-α), p53 activation indirectly by measuring p21 or mdm2 expression using immunohistochemistry, microRNA regulation of insulin signaling in adipose tissue: miR-103, miR-107, miR-29.
Study NCT04113122 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: OTHER
Intervention: Subcutaneous fat biopsy
Description: An abdominal subcutaneous fat biopsy will be performed 7-10 cm on the right side of the umbilicus. Before the fat biopsy local anesthesia is applied subcutaneously. An amount of 30 mg fat tissue will be collected using needle aspiration.~In these fat biopsies senescent cells will be detected by p16, p21 and yH2Ax staining. Furthermore, we will measure platinum levels (ICP-MS), adipocytokines (leptin, adiponectin, interleukin-6, PAI-1, TNF-α), p53 activation indirectly by measuring p21 or mdm2 expression using immunohistochemistry, microRNA regulation of insulin signaling in adipose tissue: miR-103, miR-107, miR-29.
Study NCT03176836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Whole body STIR MRI
Description: Standard technique that detects abnormalities related to excess of water in tissues (edema).
Study NCT03176836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: DW-MRI
Description: MRI technique that analyzes areas of dead cells within tissues, present in some types of tumor.
Study NCT03176836 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PET-MRI
Description: MRI technique that detect's the cells' use of glucose, more intensely in harmful cells.
Study NCT01441102 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextromethorphan hydrobromide
Description: Participants instructed to take 60 mg dextromethorphan capsules orally two times a day for 24 months.
Study NCT04084314 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Erenumab
Description: Erenumab was supplied as a pre-filled pen (auto-injector) for subcutaneous injection.
Study NCT01218126 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: losmapimod
Description: comparison of different dosages of drug 2.5 mg, 7.5 mg or 15 mg
Study NCT01218126 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: placebo comparison with active
Study NCT01752673 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visualized pulmonary embolism computer task model
Description: This group of participants was presented and trained to use a visual representation of diagnostic pathway for pulmonary embolism. The design of this visual representation is based on Bayes theorem and cognition enhancing visual design principles.
Study NCT01752673 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Didactic review lecture
Description: This group of participants was presented with a didactic lecture covering the diagnostic approach of pulmonary embolism.
Study NCT05243758 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group video fiberscope of experienced practitioner
Description: One of the classical alternatives to laryngoscopy in difficult endotracheal intubation is video laryngoscopyvideo fiberscope( Karl Storz GmbH \&Co. KG, Tuttlingen, Germany). Reaching the image from the patient with pre- and from the cervical point of view, or from the cervical point of view, to be completed with a good view from a large screen to be completed with an image before and within intubation. It also facilitates learning in education.
Study NCT05243758 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group video laryngoscope of experienced practitioner
Description: Intubation Pending Difficult as well as challenging . Fiberoptic (fiberscope) intubation is the gold standard in difficult airway. Lacking this supplement, it will be widely used for practice, as it is suitable for video laryngeal.
Study NCT05243758 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group video fiberscope of less experienced practitioner
Description: One of the classical alternatives to laryngoscopy in difficult endotracheal intubation is video laryngoscopy video fiberscope( Karl Storz GmbH \&Co. KG, Tuttlingen, Germany). Reaching the image from the patient with pre- and from the cervical point of view, or from the cervical point of view, to be completed with a good view from a large screen to be completed with an image before and within intubation. It also facilitates learning in education.
Study NCT05243758 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Group video laryngoscope of less experienced practitioner
Description: Entubation pending difficult as well as challenging . Fiberoptic (fiberscope) intubation is the gold standard in difficult airway. Lacking this supplement, it will be widely used for practice, as it is suitable for video laryngeal.Storz DCI Video Laryngoscope (Karl Storz GmbH \&Co. KG, Tuttlingen, Germany)
Study NCT03157518 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Seeking Health Probiota Bifido
Description: • This is a proof of concept study to demonstrate that oral probiotic use can modulate the airway microbiome. After informed consent has been obtained, this study will consist of 2 visits over a four week time period. Each visit will include a blood draw (30ml) and a research bronchoscopy/ bronchoalveolar lavage (BAL) (200ml) visit . A urine pregnancy test will be done on all females of childbearing potential prior to the first BAL as well as a CBC, BMP, and blood clotting tests in all participants. Following the first BAL, subjects will be asked to take an over the counter probiotic supplement (Seeking Health Probiota Bifido) nightly which will be provided to the participant by the study coordinator until the 2nd BAL is performed 4 weeks after the first BAL.
Study NCT03732183 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Podcast SMART-3RP
Description: 28 daily podcasts, each 15 minutes.
Study NCT01761097 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Endocuff attachment
Description: Endocuff
Study NCT04653766 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ir-CPI - Dose 1
Description: 6 participants received a single intravenous dose of 1.5 mg/kg of Ir-CPI during 6 hours
Study NCT04653766 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ir-CPI - Dose 2
Description: 6 participants received a single intravenous dose of 3.0 mg/kg of Ir-CPI during 6 hours
Study NCT04653766 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ir-CPI - Dose 3
Description: 6 participants received a single intravenous dose of 6.0 mg/kg of Ir-CPI during 6 hours
Study NCT04653766 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ir-CPI - Dose 4
Description: 6 participants received a single intravenous dose of 9.0 mg/kg of Ir-CPI during 6 hours
Study NCT04653766 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: For each dose group, 2 additional participants received a single intravenous dose of placebo during 6 hours (8 in total).
Study NCT02381886 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IDH305
Study NCT03088826 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Morphine Sulfate
Description: 15mg PO morphine sulfate
Study NCT03088826 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Oxycodone
Description: 10mg Oxycodone
Study NCT05566093 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: EUS-guided ethanol ablation
Description: After puncturing with the needle, 95% ethanol under the guidance of EUS was injected into the tumor. The injection volume of ethanol was estimated according to the following principles: (1) The injection volume was not larger than the tumor spherical volume. (2) Injection volume was reduced when the tumor was adjacent to the pancreatic duct or vessel. (3) Injection volume for the lesions with repeated EUS-FNI was reduced.
Study NCT05566093 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: EUS-guided lauromacrogol ablation
Description: After puncturing with the needle, lauromacrogol under the guidance of EUS was injected into the tumor. The injection volume of lauromacrogol was estimated according to the following principles: (1) The injection volume was not larger than the tumor spherical volume. (2) Injection volume was reduced when the tumor was adjacent to the pancreatic duct or vessel. (3) Injection volume for the lesions with repeated EUS-FNI was reduced.
Study NCT03088826 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Acetaminophen
Description: 650 mg Acetaminophen
Study NCT01163370 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: creatine supplementation
Description: 20g/d for 7 days followed by 5g/d for 23 weeks
Study NCT01163370 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: exercise training
Description: resistance training twice a week for 24 weeks
Study NCT01163370 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: exercise training
Description: resistance training twice a week for 24 weeks
Study NCT01163370 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: placebo (dextrose)
Description: 20g/d for 7 days followed by 5g/d for 23 weeks
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vincristine
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Daunorubicin
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Prednisone
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: L-asparaginase
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciclophosphamide
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Metotrexate
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARA-C
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hidrocortisone
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Mercaptopurine
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VP-16
Study NCT02036489 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexametasone
Study NCT00808275 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Dietary calcium
Description: Dairy and non-dairy calcium provided as a part of diet in the amounts of 500 mg/day and 1500 mg/day. Diet contained 70% of daily caloric requirements.
Study NCT06580639 — intervention group
Intervention type: OTHER
Intervention: No intervention.
Description: Blood sampling for analysis of mycobacterial growth inhibition assay (MGIA) analysis.
Study NCT03207659 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Basketing in RIRS
Description: Treament of renal stones by fragmentation of stone under direct vision through a flexible ureteroscope and then actively extracting them using a basket
Study NCT03207659 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Dusting in RIRS
Description: Treament of renal stones by dusting the stone under direct vision through a scope and then leaving them to pass spontaneously
Study NCT02780700 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nintedanib
Study NCT02780700 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Capecitabine
Study NCT02944643 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mindfulness and Support Groups
Study NCT02768623 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Pharmacist led Asthma Management
Study NCT02768623 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Pharmacist Intervention (when requested by patient)
Study NCT03230708 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Erythrocytes derived MPs containing MTX
Description: General conventional treatment and peritoneal drainage, additional peritoneal perfusion with erythrocytes derived MPs containing MTX
Study NCT03230708 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: convention drugs
Description: according to usage method of drugs
Study NCT01769300 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Clinical decision support for medication titration
Description: Electronic health record-based clinical decision support for ADHD medication titration.
Study NCT04445636 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dexmedetomidine
Description: Caudal block with Dexametomedine as an adjuvant to bupivacaine.
Study NCT04445636 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: Addition of morphine as adjuvant to bupivacaine during caudal block.
Study NCT03058588 — intervention group
Intervention type: GENETIC
Intervention: Analysis with molecular biology
Description: Molecular screening by next generation sequencing (NGS) platform, for known and unknown mutations potentially associated with the disease
Study NCT03965897 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Acceptance and Committment Therapy (ACT)
Description: Overall, the goal of the ACT intervention is to cultivate psychological flexibility: to help Veterans respond to life events in ways which do not exacerbate difficulties or restrict engagement in meaningful activities. It increases patients' awareness of behaviors that exacerbate the pain (such as struggling with it) and recognition of avoidance strategies that interfere with life engagement.
Study NCT03965897 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Attention Control (AC)
Description: Information on any other coping practices will be omitted. The group facilitators will present one topic at a time, using the Pain Manual, and the participants will discuss and reflect about issues and experiences related to each topic. If necessary, the group facilitators will raise specific discussion questions to facilitate group dialogue and participant involvement.
Study NCT02414191 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Benchmarked Feedback
Description: Participants receive data, during the 6 month intervention phase, regarding their monthly temperature management performance in the form of benchmarked feedback, which is the measure of their performance in comparison the standard set by the hospital.
Study NCT02414191 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: Ranked Feedback
Description: Participants receive data, during the 6 month intervention phase, regarding their monthly temperature management performance in the form of ranked feedback, which is the measure of their performance in comparison to their peers.
Study NCT03694639 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: ganglion impar block
Description: CT sections were done in the axial plane 4 mm slice thickness to detect the site of sacrococcygeal disk. After a suitable section was confirmed, two distances were measured, one from patient's spine to the proper site of entry and the other from the site of entry to the target point.22 gauge spinal needle 12 cm was introduced until reach anterior to sacrococcygeal disk. When the needle tip location was ideal, 2 ml lidocaine mixed with1ml of radiopaque dye was injected. CT sagittal section was done to verify the retroperitoneal distribution of the dye. After good contrast spread confirmation, 5 ml bupivacaine 5% with 14 mg/2 ml betamethasone was injected
Study NCT00680511 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Adolescent Methamphetamine Treament (AMT)
Description: AMT Group Therapy plus Functional Family Therapy (FFT)
Study NCT00680511 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Functional Family Therapy (FFT)
Description: FFT
Study NCT03332368 — intervention group
Intervention type: OTHER
Intervention: Traditional Chinese medicine
Description: Chinese medicine has a long history of prevention and treatment of breast cancer, the effect is obvious. Chinese medicine its mechanism of action is from the whole, adjust the body yin and yang, blood, viscera function balance, emphasizing the combination of governance and external treatment of the combination of thinking, according to different clinical syndromes, using syndrome differentiation.
Study NCT04866212 — intervention group
Intervention type: BEHAVIORAL
Intervention: Beery- Buktenica Developmental Test of Visual Motor Integration
Description: Investigation of visual motor integration, motor coordination and visual perception by Beery- Buktenica Developmental Test of Visual Motor Integration.
Study NCT04866212 — intervention group
Intervention type: BEHAVIORAL
Intervention: Jebsen Taylor Hand Function Test
Description: Investigation of hand skills by Jebsen Taylor Hand Function Test
Study NCT04866212 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Participation and Environment Measure - Children and Youth
Description: Investigation of participation by Participation and Environment Measure - Children and Youth
Study NCT03278418 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Tricuspid Valve Repair
Description: It will be performed according to the surgeon preference
Study NCT03278418 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Left-sided valve surgery
Description: It will be performed according to the surgeon preference
Study NCT03278418 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Left-sided valve surgery
Description: It will be performed according to the surgeon preference
Study NCT03538015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carvedilol 3.125 mg
Description: Participants will receive a 3.125 mg oral dose of carvedilol twice daily during the 4-week treatment period
Study NCT03538015 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Carvedilol 2.5 mg
Description: Participants will receive a 2.5 mg oral dose of carvedilol twice daily during the 4-week treatment period
Study NCT03538015 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo capsule
Description: Participants will receive a matching oral dose of placebo capsule twice daily during the 4-week treatment period
Study NCT00387855 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: SOS program
Description: screening and didactic programming to raise awareness of depression suicidality
Study NCT00912548 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: goserelin
Description: 1. Zoladex™ administration:~   Zoladex™ depot is available as a sterile disposable syringe. The depot is administered subcutaneously under the abdominal skin under sterile conditions. If necessary the injection site may be pre-treated with a local anaesthetic.~2. Sequence of administration Zoladex depot:~   The substance is administered for 24 months (2 years) at 28-day intervals (a period of 34 days between 2 administrations must not be exceeded).~3. Dosage:~   Each depot contains 3.6mg Zoladex. The substance Zoladex is contained in a while cylindrical rodlet .~4. Storage instructions for Zoladex™ Zoladex™ is kept a room temperature.
Study NCT00912548 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: tamoxifen
Description: 1. Dose and period of Tamoxifen therapy:~   Tamoxifen is administered in tablet form. Each day 2 X 10 mg or 1 X 20 mg Tamoxifen are taken in the form of the respective tablet.~2. Storage instructions for Tamoxifen Tamoxifen is stored at room temperature away from light.
Study NCT00912548 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tamoxifen
Description: 1. Dose and period of Tamoxifen therapy:~   Tamoxifen is administered in tablet form. Each day 2 X 10 mg or 1 X 20 mg Tamoxifen are taken in the form of the respective tablet.~2. Storage instructions for Tamoxifen Tamoxifen is stored at room temperature away from light.