AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT02320422 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Behavioral Telehealth
Description: The telemetric intervention (administered via telephone, or interactive video chat applications such as FaceTime ® or Skype ®) will enable the intervention team (IT) to address non-adherence from a remote location, using a structured, tailored approach
Study NCT03848702 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Distal radius fracture brace
Description: The distal radius fracture brace is constructed from biocompatible materials (like polylactic acid; PLA) and the skin is protected by commercially available and approved waterproof padding (like Aquacast®). The major brace components are connected and reinforced with carbon rods and plastic bolt-nut connections. PLA is extensively used, for example in surgical implants, but also as biological alternative for plastics. Aquacast® is approved and used as waterproof padding in swim plaster. The biomechanical function of the distal radius brace has been tested successfully in an ex vivo setting (results to be published). The DRFB includes the distal forearm, wrist an base of the hand. The thumb and fingers are free and the DRFB provides more movement than classical casting.
Study NCT03090867 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Relatives or surrogates are encouraged to perform care
Description: The relative or surrogate will perform at least two cares a week among feeding, mouth care, hair wash, shaving, eye care, hand, foot and face massage.~All care are planned and perform under the supervision or/and in collaboration with a caregiver.~The relative or surrogate will give his opinion by completing the study questionnaires.
Study NCT03090867 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional ,care
Description: The relative or surrogate will not be encouraged to perform care. The management of the relative or surrogate wi ll not changed from the regular standard of the ICU.
Study NCT03036384 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HB Prilocaine 2% (varying dose)
Description: Varying dose of hyperbaric (HB) prilocaine 2% according to sensitive response of previous subjects. The dose of hyperbaric prilocaine 2% will be administrated intrathecally with 100µg of morphine and 2.5µg of sufentanyl
Study NCT02295046 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Amlodipine besylate/Atorvastatin calcium
Description: Amlodipine besylate/Atorvastatin calcium 10/80 mg
Study NCT02295046 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Amlodipine besylate/Atorvastatin calcium
Description: Amlodipine besylate/Atorvastatin calcium 10/80 mg
Study NCT03573557 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Pink Pad
Description: Pink Pad made by Xodus Medical Inc. used for patients in steep Trendelenburg position during surgery.
Study NCT03573557 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bean Bag
Description: Vac-Pac Bean Bag made by Olympic used for patients in steep Trendelenburg position during surgery.
Study NCT00536926 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Home spirometer with BT-cellphone
Description: Data transfer of home spirometry recordings via bluetooth to clinical database.
Study NCT00536926 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Home spirometer w/o BT
Description: Standard home spirometry
Study NCT03573557 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Gel Pad
Description: Gel Pad used for patients in steep Trendelenburg position during surgery.
Study NCT00815490 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Desaturation
Description: Reduction in blood oxygen saturation by sequential reduction in inspired gas composition. Steps are of 6 minutes duration with reduction in pulse oximeter oxygen saturation from 100 to 70%.
Study NCT02189083 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: TSD
Description: TSD is composed of 15 individual Chinese medicines: Astragalus Membranaceus, Semen Coicis, Poria, Curcuma longa L, and Fritillaria Thunbergii Miq, Cassia twig, Pollen typhae, Resina draconis, Lithospermum erythrorhizon, Halloysitum Rubrum, Rhizoma Corydalis processed with vinegar, Hirudo, Calcined corrugated sub , Oyster Shell and Laminaria Japonica Aresch.~High dose (127g) or Low dose (69g) TSD decoction boiled as 200ml per bag; 2 bags per day, 6 days per week; Orally in-take one bag of TSD decoction in morning and another in evening after meal; The whole treatment lasts for 16 weeks.
Study NCT02189083 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: TSD
Description: TSD is composed of 15 individual Chinese medicines: Astragalus Membranaceus, Semen Coicis, Poria, Curcuma longa L, and Fritillaria Thunbergii Miq, Cassia twig, Pollen typhae, Resina draconis, Lithospermum erythrorhizon, Halloysitum Rubrum, Rhizoma Corydalis processed with vinegar, Hirudo, Calcined corrugated sub , Oyster Shell and Laminaria Japonica Aresch.~High dose (127g) or Low dose (69g) TSD decoction boiled as 200ml per bag; 2 bags per day, 6 days per week; Orally in-take one bag of TSD decoction in morning and another in evening after meal; The whole treatment lasts for 16 weeks.
Study NCT02506166 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Positive Airway Pressure Therapy
Description: Positive Airway Pressure Therapy will be used in Group 3 for treatment of predominant obstructive sleep apnea
Study NCT04366609 — intervention group
Intervention type: DRUG
Intervention: Methylphenidate
Description: Treatment with methylphenidate through dose escalation
Study NCT04164953 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Surgical treatment
Description: Surgical treatment of Dupuytren's disease. Average from 2 to 4 joints per hand operated on simultaneously
Study NCT02277769 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dupilumab
Description: Subcutaneous injection alternated among the different quadrants of the abdomen, upper thighs and upper arms.
Study NCT02697526 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Terumo
Study NCT02697526 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Tensoplast
Study NCT03424772 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Whole genome sequencing
Description: WGS will be performed for the trio
Study NCT03036384 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: HB Prilocaine 2%
Description: The dose of 45mg of hyperbaric (HB) prilocaine 2% will be administrated intrathecally with 100µg of morphine and 2.5µg of sufentanyl
Study NCT03036384 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sufentanil
Description: 2.5µg sufentanyl
Study NCT02277769 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo (for Dupilumab)
Description: Subcutaneous injection alternated among the different quadrants of the abdomen, upper thighs and upper arms.
Study NCT02277769 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (for Dupilumab)
Description: Subcutaneous injection alternated among the different quadrants of the abdomen, upper thighs and upper arms.
Study NCT03069274 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Intervention
Description: General nutritional recommendations, change drinking habits
Study NCT03069274 — intervention group
Intervention type: BEHAVIORAL
Group type: OTHER
Intervention: General nutritional recommendations
Description: Only general nutritional recommendations were given
Study NCT03120156 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: sensomotoric insoles
Description: sensomotoric insoles were published by Jahrling (2007) and have a certain shape that could improve balance abilities. The toes 2-4 are higher that toe 1, so that the tendons of the toe-flectors are pre-stressed.
Study NCT03120156 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: normal standard insoles
Description: Normal standard insole like you will get them by receipe from an orthotic shop
Study NCT03652571 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nortriptyline
Description: Nortriptyline escalating dose regimen:~Week 1-2: 10mg Week 3-4: 25mg Week 5-12: 50mg
Study NCT03652571 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo
Study NCT02524743 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: acetaminophen
Description: The venous drainage was occluded for 120 seconds by using a rubber tourniquet on the upper arm and the patients were pretreated acetaminophen (50mg and 25 mg IV) before the injection of rocuronium.Twenty seconds after the administration of rocuronium, 5 mg/kg of thiopental was administered IV. After orotracheal intubation, anesthesia was continued with sevofluorane during 40 % oxygen and 60 % air. Twenty-four hours after the operation, the injection site was checked for any complications, such as pain (absent/ present), swelling or allergic reaction by an anesthesiologist who did not know which drug was administered.
Study NCT02524743 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lidocaine
Description: The venous drainage was occluded for 120 seconds by using a rubber tourniquet on the upper arm and the patients were pretreated lidocaine (20 mg and 40 mg IV) before the injection of rocuronium.Twenty seconds after the administration of rocuronium, 5 mg/kg of thiopental was administered IV. After orotracheal intubation, anesthesia was continued with sevofluorane during 40 % oxygen and 60 % air. Twenty-four hours after the operation, the injection site was checked for any complications, such as pain (absent/ present), swelling or allergic reaction by an anesthesiologist who did not know which drug was administered.
Study NCT02524743 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: The venous drainage was occluded for 120 seconds by using a rubber tourniquet on the upper arm and the patients were pretreated 5 ml iv normal saline before the injection of rocuronium.Twenty seconds after the administration of rocuronium, 5 mg/kg of thiopental was administered IV. After orotracheal intubation, anesthesia was continued with sevofluorane during 40 % oxygen and 60 % air. Twenty-four hours after the operation, the injection site was checked for any complications, such as pain (absent/ present), swelling or allergic reaction by an anesthesiologist who did not know which drug was administered.
Study NCT04255680 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Buccal Swabs and Blood Draws
Description: Buccal Swabs - Frataxin \& specific RNA markers Blood Draws - Lipid panel, Uric Acid, Protein Marker Analysis and PAX Gene RNA Analysis
Study NCT01333904 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PUR118
Description: inhaled
Study NCT02355938 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fidaxomicin 200 mg
Description: Fidaxomicin 200 mg every 12 hours
Study NCT02355938 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 1 dose of placebo every 6 hours x 2 doses
Study NCT02355938 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vancomycin
Description: Vancomycin 125 mg every 6 hours
Study NCT02180139 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: transcranial direct current stimulation
Description: tDCS using a constant current of 2 mA via two 35 cm2 saline soaked sponge electrodes. Treatment is 1x/day for 4 days.
Study NCT02180139 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: transcranial direct current stimulation
Description: tDCS using a constant current of 2 mA via two 35 cm2 saline soaked sponge electrodes. Treatment is 1x/day for 4 days.
Study NCT02246543 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Water, Toast \& Egg (Yolk only) + 0.1g 13C Octanoic Acid
Study NCT02246543 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: HPL
Description: High Protein Smoothie (Liquid): 30% protein; 30% fat and 40% CHO + 0.1g 13C Octanoic Acid
Study NCT02246543 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: LPL
Description: Low Protein Smoothie (Liquid): 15% protein; 30% fat and 55% CHO + 0.1g 13C Octanoic Acid
Study NCT02246543 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: HPS
Description: High Protein Milk Jelly (Solid): 30% protein; 30% fat and 40% CHO + 0.1g 13C Octanoic Acid
Study NCT02246543 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: LPS
Description: Low Protein Milk Jelly (Solid): 15% protein; 30% fat and 55% CHO + 0.1g 13C Octanoic Acid
Study NCT00949403 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Radio pharmaceuticals C-11 Acetate, and C-11 Palmitate
Description: injection of C-11 Palmitate and C-11 Acetate during PET/CT to determine Liver metabolism
Study NCT03036384 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Morphine
Description: 100 µg Morphine
Study NCT02807298 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 4%articaine
Description: intraligamentary injections of 0.9 ml of 4%articaine and 1:100,000 epinephrine
Study NCT02807298 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: 2% Lignocaine
Description: Intraligamentary injections of 1.8 ml of lidocaine and 1:100,000 epinephrine
Study NCT02807298 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Epinephrine
Description: Intraligamentary injections of 1.8 ml of lidocaine and 1:100,000 epinephrine
Study NCT02807298 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Epinephrine
Description: Intraligamentary injections of 1.8 ml of lidocaine and 1:100,000 epinephrine
Study NCT04126902 — intervention group
Intervention type: OTHER
Intervention: interleukin-6, presepsin and pentraxin-3
Description: measurements and compare
Study NCT01612689 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accelerometer Device
Description: A sensor platform that enables physiological monitoring in routine, home or office environments.
Study NCT02834702 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Sinew acupuncture
Description: The subject is asked to be on sitting posture. The skin around the needling points is disinfected with a 75% alcohol swap. A tube-guided, sterilized, disposal needle is then inserted (at a small angle to the skin) into the acupoint at 0.5-1 cun (depending on point location and body size of the subject). No needle sensation (deqi sensation) is required. A piece of surgical adhesive tape will be applied to the needle immediately after insertion.
Study NCT02834702 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture
Description: The procedure in the sham acupuncture group will be as similar to that of the acupuncture group as possible. In the sham acupuncture group, however, a mock plastic needle guiding tube is tapped on the surface of each acupoint (Ashi point and traditional acupoints) to produce some discernible sensation. A piece of adhesive tape is immediately applied to fix the needle on the dermal surface tapped, without needle insertion. In addition, a plastic tube-guided needle is superficially inserted at the sham point at less than 5mm in depth.
Study NCT03291743 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Capsule endoscopy
Description: PillCam(TM) CROHN'S CAPSULE
Study NCT02809547 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Dried Blood Spot device
Study NCT03291743 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Capsule endoscopy
Description: PillCam(TM) CROHN'S CAPSULE
Study NCT02430467 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Caregiver-guided pain management training (CG-PMT)
Description: Patient-caregiver dyads in the CG-PM arm of the study will receive 3 50-minute sessions via Skype with a masters-level therapist over a 3-week period. The intervention integrates educational information about cancer pain and its management with a behavioral training program to teach patients and caregivers pain coping skills including relaxation, imagery, and activity pacing, and to teach caregivers how to guide and coach the patient in the practice and application of these pain control techniques.
Study NCT02430467 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Enhanced treatment-as-usual (TAU)
Description: Patient-caregiver dyads in the Enhanced TAU condition will receive the same educational video and booklet on cancer pain and its management that is used as part of the CG-PMT intervention. They will also receive iPads with icons linked to reputable websites that provide educational information on cancer including cancer pain (e.g., ACS, NCI) and will be encouraged to utilize them for information and support. However, they will not meet with a study interventionist nor receive any training in behavioral pain coping skills.
Study NCT01346319 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: ABT-SLV361
Description: For dose groups 1, 2 and 3 medication is taken 1 time per day the first day followed by 2 times per day for 14 days. For dose groups 4 and 5, medication is taken 1 time per day for the first day followed by 2 times per day for 28 days.
Study NCT01346319 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: placebo
Description: For dose groups 1, 2 and 3 medication is taken 1 time per day the first day followed by 2 times per day for 14 days. For dose groups 4 and 5, medication is taken 1 time per day for the first day followed by 2 times per day for 28 days.
Study NCT02809547 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Dried Blood Spot device
Study NCT03333798 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive-Behavioral Intervention
Description: A Cognitive-Behavioral intervention will be delivered by psychologists with LPCWs support. LPCWs who will be under the supervision and guidance of psychologists.~Volunteers will receive 11 weekly sessions of which six will be provided by psychologists and five by LPCWs.~The Cognitive-Behavioral component will be delivered through a set modules that will cover the following components:~* The Cognitive-Behavioral model~* Tackling traumatic events~* Cognitive reprocessing~* Relaxation techniques~* Prevention of revictimization~* Behavioral reactivation for the start of a new life The intervention will be given within the health system and volunteers will be seen if necessary by an interdisciplinary team including social workers, general physicians and psychiatrists.
Study NCT03333798 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard psychosocial care
Description: The active control group will receive standard psychosocial care for intimate partner violence, provided by the participating health centers. Standard care is delivered by psychologists, social workers, general physicians and psychiatrists. Additionally, patients receive extramural support which includes telephone calls or domiciliary visits from a variety of health professionals (doctors, nurses, social workers and nursing assistants).~Psychology consultations typically occur every four weeks in each health center. Psychologists use a variety of approaches according to their personal preferences, including humanist, psychoanalytic, psychodynamic and cognitive-behavioral approaches. At the end of the intervention psychologists will be asked which approach or approaches they used.
Study NCT00259064 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gefitinib
Study NCT00259064 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT04077619 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Modern pain neuroscience approach
Description: Modern pain neuroscience approach. The modern pain neuroscience approach includes 3 sessions (1 group and 2 individual sessions) of therapeutic pain neuroscience education followed by 15 individual sessions of dynamic and functional cognition-targeted exercise therapy and stress management techniques. In addition, participants will be instructed to perform a daily set of home exercises. The exercises will be performed in a time-contingent way. The 18 sessions will be spread over a period of 16 weeks.
Study NCT04077619 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Usual care physiotherapy
Description: Usual care evidence-based physiotherapy The usual care evidence-based physiotherapy includes 3 sessions (1 group and 2 individual sessions) of neck school followed by 15 individual sessions of graded and active exercise therapy focusing on strength, flexibility, endurance, and ergonomic principles. In addition, participants will be instructed to perform a daily set of home exercises. The exercises will be performed in a symptom-contingent way. The 18 sessions will be spread over a period of 16 weeks.
Study NCT03233529 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Crisaborole ointment 2% BID
Description: Crisaborole ointment 2% BID for 15 days (double blind); additional 28 days (open label)
Study NCT03233529 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo ointment (vehicle)
Description: Placebo ointment (vehicle) BID for 15 days (double blind)
Study NCT01075256 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 5% calcium sodium phosphosilicate toothpaste
Description: Low concentration calcium sodium phosphosilicate tubule occlusion agent
Study NCT01075256 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: 7.5% calcium sodium phosphosilicate toothpaste
Description: High concentration calcium sodium phosphosilicate tubule occlusion agent
Study NCT03120156 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: No insoles
Description: control group with no insoles in the shoes