AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04919850 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: A placebo consisting of capsules containing the same excipients except the active compounds, and the same coating
Study NCT04163237 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PD-1
Description: PD-1 (programmed death receptor 1), an important immunosuppressive molecule, is an immunoglobulin superfamily and is a membrane protein of 268 amino acid residues. It was originally cloned from apoptotic mouse T cell hybridoma 2B4.11. Immunomodulation targeting PD-1 has important implications for anti-tumor, anti-infective, anti- autoimmune diseases and organ transplant survival. Its ligand PD-L1 can also be used as a target, and the corresponding antibodies can also play the same role. PD-1 and PD-L1 bind to initiate programmed cell death of T cells, allowing tumor cells to gain immune escape.
Study NCT03682666 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Kinesiotaping
Description: Kinesio tape would be applied over the extensor muscles of the affected hand for facilitating the extension of hand. We will apply the tape from the upper 1/3 length of dorsal side of the forearm and split the tape into five equal bars to the distal interphalangeal joint of each finger along the finger bones. This intervention would be executed for five days per week for three weeks.
Study NCT03682666 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Kinesiotaping
Description: Kinesio tape would be applied over the extensor muscles of the affected hand for facilitating the extension of hand. We will apply the tape from the upper 1/3 length of dorsal side of the forearm and split the tape into five equal bars to the distal interphalangeal joint of each finger along the finger bones. This intervention would be executed for five days per week for three weeks.
Study NCT03682666 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: modified Constraint Induced Movement Training
Description: A 2-hour time period would be arranged to constraint patient's unaffected hand by using a bandage by a therapist. During this two hours, patients would not be allowed to use this unaffected to do any activity, so that they will need to use the affected hand. The caregivers would also be educated to provide less help if it is not necessary. This intervention would be executed two hours a day for five days per week, for three weeks.
Study NCT03682666 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: modified Constraint Induced Movement Training
Description: A 2-hour time period would be arranged to constraint patient's unaffected hand by using a bandage by a therapist. During this two hours, patients would not be allowed to use this unaffected to do any activity, so that they will need to use the affected hand. The caregivers would also be educated to provide less help if it is not necessary. This intervention would be executed two hours a day for five days per week, for three weeks.
Study NCT03682666 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: Sham taping
Description: A short piece of kinesio tape would be cut into half and applied over the lateral side of the forearm from the lateral epicondyle till the half of the forearm. The tape would not cover the both the flexor and extensor muscle bellies.
Study NCT02151760 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 18F-DCFPyL
Study NCT00851383 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad35-GRIN/ENV
Description: This is a dose-escalation trial. Each group will receive the Ad35-GRIN/ENV vaccine at different dosage levels.
Study NCT00851383 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Ad35-GRIN
Description: This is a dose-escalation trial. Group D will receive the Ad35-GRIN vaccine.
Study NCT00881712 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: PET positive nodal disease measuring 15 mm or greater
Description: Proton radiation at 2 cobalt gray equivalent per fraction to a total of 74 cobalt gray equivalent with concomitant weekly chemotherapy.
Study NCT00881712 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: PET positive nodal disease measuring less than 15 mm
Description: Proton radiation at 2 cobalt gray equivalent per fraction to a total of 60 cobalt gray equivalent with concomitant weekly chemotherapy.
Study NCT02793505 — intervention group
Intervention type: DRUG
Intervention: metformin
Description: This is not an intervention but an observed exposure.
Study NCT00881712 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Patients considered resectable
Description: Proton radiation at 2 cobalt gray per fraction. Re-evaluation performed between days 18-22 of treatment. If considered resectable after re-evaluation, radiotherapy will discontinue after a total of 50 cobalt gray equivalent and surgery will be performed.
Study NCT03283592 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rank-Heat Plot
Description: provides a visual presentation of treatment hierarchy across multiple outcomes
Study NCT03283592 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: SUCRA Plot
Description: provides a visual presentation of treatment ranking for a single outcome.
Study NCT03900351 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Wii fit protocol of virtual reality games
Description: the Wii fit session by standing on the Wii fit board with bare feet, hands on hips and both eyes open. Pretest on Wii fit was done to make the subject familiar with the board and tasks of weight shift .
Study NCT03900351 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Regular exercise rehabilitation protocol
Description: It will be according to the criterion of Adams et al. (2012).
Study NCT03900351 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Regular exercise rehabilitation protocol
Description: It will be according to the criterion of Adams et al. (2012).
Study NCT00258245 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: ascorbic acid
Description: Ascorbic Acid (Vit C)- 1000 mg IVPB after Arsenic Trioxide \[ATO\] days 1, 4, 8, 11
Study NCT00258245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: arsenic trioxide
Description: Arsenic Trioxide (Trisenox)- 0.10→0.15→0.25 mg/kg/dose IVPB days 1, 4, 8, 11
Study NCT00258245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: bortezomib
Description: Bortezomib (Velcade)- 0.7→1.0 mg/m2 IVP days 1, 4, 8, 11
Study NCT00258245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexamethasone
Description: Dexamethasone (Decadron)- 40 mg/days IVPB or PO d 1, 4, 8, 11
Study NCT00258245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: thalidomide
Description: Thalidomide (Thalomid) - 50 mg/day by mouth (PO)
Study NCT00258245 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: Aspirin - 325 mg by mouth (PO) every day
Study NCT01634971 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Internal Drainage of Pancreatic Duct after pancreatomy
Description: the Intervention name is: Internal Drainage of Pancreatic Duct after pancreatomy, a stent was placed in the pancreatic duct, external drainage of the stent is defined as control group(the stent will be tans-abdomen and as a drainage of pancreatic fluid), and internal drainage of the stent is defined as interventional(or experimental) group, with the stent very short(2cm) and placed in jejunum.
Study NCT04942691 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical activity
Description: training with trampoline. Each session lasted sixty minutes. Organization: a 5 minutes warm-up with breathing and mobility exercises from upper to lower body, central phase with jumping exercises involving the total body and 5 minutes of cool-down phase with total body active stretching exercise.
Study NCT01689701 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hizikia Fusiformis extract
Description: Hizikia Fusiformis extract(1.3g/d)
Study NCT04163237 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sorafenib
Description: Sorafenib tosylate is a novel multi- target anti-tumor drug developed by Bayer Pharmaceuticals, Germany, which acts on both tumor cells and tumor blood vessels. It has a dual anti-tumor effect: it directly inhibits tumor cell proliferation by blocking RAF/MEK/ERK-mediated cell signaling pathways, and also by inhibiting VEGFR and platelet- derived growth factor (PDGF) receptors. Blocking the formation of tumor neovascularization, indirectly inhibiting the growth of tumor cells.
Study NCT04163237 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Sorafenib
Description: Sorafenib tosylate is a novel multi- target anti-tumor drug developed by Bayer Pharmaceuticals, Germany, which acts on both tumor cells and tumor blood vessels. It has a dual anti-tumor effect: it directly inhibits tumor cell proliferation by blocking RAF/MEK/ERK-mediated cell signaling pathways, and also by inhibiting VEGFR and platelet- derived growth factor (PDGF) receptors. Blocking the formation of tumor neovascularization, indirectly inhibiting the growth of tumor cells.
Study NCT04242212 — intervention group
Intervention type: BEHAVIORAL
Intervention: Misoprostol sourced from clinics
Description: One cohort of women using misoprostol sourced from clinics
Study NCT04242212 — intervention group
Intervention type: BEHAVIORAL
Intervention: Misoprostol sourced from PMVs
Description: One cohort of women using misoprostol sourced from PMVs
Study NCT05561231 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation with C blade
Description: Intubation with C blade of CMAC videolaryngoscope
Study NCT05561231 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Intubation with D blade
Description: Intubation with D blade of CMAC videolaryngoscope
Study NCT00856700 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: GLP-1 infusion
Description: Participants will receive intraarterial infusion of GLP-1 (20 pmol/ml solution) for 100 min.
Study NCT01697683 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Probiotic Lactobacilli
Description: Two capsules per day containing either probiotic lactobacilli or placebo for 12 weeks
Study NCT01697683 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT01310166 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fingolimod
Study NCT03733275 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Lidocaine
Description: for experimental arm, lidocaine spray and lidocaine bupivacine mixture-soaked nasal packing vs. for placebo arm, normal saline spray and packing
Study NCT03733275 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Lidocaine
Description: for experimental arm, lidocaine spray and lidocaine bupivacine mixture-soaked nasal packing vs. for placebo arm, normal saline spray and packing
Study NCT03478969 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Accu-Chek® Solo micropump system
Description: Medical device for subcutaneous delivery of insulin in a personalized way.
Study NCT03478969 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: mylife™ OmniPod® Insulin Management System
Description: A patch pump system delivering insulin.
Study NCT03374800 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (0.9% saline)
Description: normal saline
Study NCT03374800 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Pantoprazole
Description: 40 mg powder for injection reconstituted with 0.9% saline
Study NCT02793505 — intervention group
Intervention type: DRUG
Intervention: any drug not known as a major teratogen or major fetotoxicant
Description: This is not an intervention but an observed exposure.
Study NCT01012310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-04531083 or Placebo
Description: Subjects will receive multiple oral doses of less than or equal to 100mg PF-04531083 or placebo for 14 days.
Study NCT01012310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-04531083 or Placebo
Description: Subjects will receive multiple oral doses of less than or equal to 300mg PF-04531083 or placebo for 14 days.
Study NCT01012310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-04531083 or Placebo
Description: Subjects will receive multiple oral doses of less than or equal to 500mg PF-04531083 or placebo for 14 days.
Study NCT01012310 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PF-04531083 or Placebo
Description: A fourth cohort may be used to investigate alternative dosing regimens, formulations or food effects.
Study NCT01689701 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo(1.3g/d)
Study NCT01605877 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
Description: Multifocal IOL with extended secondary focal point implanted for long-term use over the lifetime of the cataract patient
Study NCT03854305 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: PRV-6527
Description: Treatment
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PedsQL Cancer Module
Description: The PedsQL cancer module acute version is a 27 item assessment that includes eight scales including pain (2 items), nausea (5 items), anxiety related to procedures (3 items), anxiety related to treatment (3 items), worry (3items), cognitive problems (5 items), perceived physical appearance and communication (3 items). This assessment will take approximately 15-30 minutes to complete.
Study NCT03854305 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Comparator
Study NCT03478969 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Multiple Daily Injections (MDI) therapy
Description: Injecting insulin as per participant's need.
Study NCT00759798 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Fludarabine
Description: 25 mg/m\^2 given intravenously on Days 2-4 of Cycle 1 and Days 1-3 of Cycles 2 and beyond.
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PedsQL Multidimensional Fatigue Scale
Description: The Multidimensional Fatigue Scale is an 18 item questionnaire encompassing 3 subscales including general fatigue (6 items), sleep and rest fatigue (6 items) and cognitive fatigue (6 items). This assessment will take approximately 10-20 minutes to complete.
Study NCT02473523 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Biodex System 3 Dynamometer
Description: The Biodex System 3 Dynamometer will be used to measure isometric quadriceps muscle contractions. Participants will be stabilized in the chair with abdominal and shoulder straps. The isometric tests for knee extension will be done on both dominant and non-dominant leg. The tests consist of 3 maximal muscle contractions each lasting five seconds separated by 40 second rest intervals. This assessment will take approximately 10 minutes to complete.
Study NCT02473523 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Jamar Hydraulic Hand Dynamometer
Description: A calibrated Jamar hydraulic hand dynamometer will be used to measure grip strength. The participant will be seated in a chair with elbow flexion to 90 degrees against torso and the forearm in neutral. The participant will grasp the device and the handle will be adjusted so that digits are able to comfortably grasp the device. The maximum score after 2 trials will be recorded as grip strength for both right and left hand. This assessment will take no more than 5 minutes to complete.
Study NCT00759798 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Cyclophosphamide
Description: 250 mg/m2 given intravenously on Days 2-4 of Cycle 1 and Days 1-3 of Cycles 2 and beyond.
Study NCT00759798 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rituximab
Description: 375 mg/m2 given intravenously on Day 1 of Course 1~All subsequent Courses: 500 mg/m2 given intravenously on Day 1 (Weeks 5,9,13,17,21)
Study NCT00864006 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Divalproex Sodium
Study NCT00864006 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Depakote DR Tablets
Study NCT02132520 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: rTMS
Description: Low frequency rTMS (either real or sham) will be applied to the contralesional hemisphere at a rate of 1Hz for 10 minutes.
Study NCT02132520 — intervention group
Intervention type: DEVICE
Group type: SHAM_COMPARATOR
Intervention: rTMS
Description: Low frequency rTMS (either real or sham) will be applied to the contralesional hemisphere at a rate of 1Hz for 10 minutes.
Study NCT02132520 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: BCI Training
Description: BCI training will consist of a series of EEG-based motor-imagery tasks with virtual feedback presented on a computer screen.
Study NCT02132520 — intervention group
Intervention type: BEHAVIORAL
Group type: SHAM_COMPARATOR
Intervention: BCI Training
Description: BCI training will consist of a series of EEG-based motor-imagery tasks with virtual feedback presented on a computer screen.
Study NCT03022968 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: [18F]T807 PET
Description: Imaging with \[18F\]T807 PET
Study NCT00859300 — intervention group
Intervention type: GENETIC
Intervention: Blood sample
Description: Blood sample Determination of genetic background
Study NCT02797743 — intervention group
Intervention type: OTHER
Intervention: Whole blood
Description: * Adults ≥18 yrs of age: up to 50 mL (5 tubes)~* Adolescents 12-17 yrs of age: up to 30 mL (3 tubes)~* Children 0-11 yrs of age: single tube (1 tube, 10 mL)
Study NCT02927249 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Given PO
Study NCT02927249 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Aspirin
Description: Given PO
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Sit and Reach Test
Description: Hamstring flexibility will be assessed by the Sit and Reach Test. The sit and reach is a test to measure hip, hamstring and lower back flexibility. To measure flexibility participants will perform the YMCA sit and reach test. Participants will sit down without shoes or socks with the soles of their feet against the vertical platform of the sit-and-reach box located at the 26 cm (a little over 10 inches) mark. Participants keep their legs straight and their hands overlapped, while reaching for a less than maximum distance twice as a warm-up. This test will take no more than 5 minutes to complete.
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Test of Motor Proficiency
Description: The Bruininks-Oseretsky Test of Motor Proficiency is a 9 item standardized assessment that includes standing with feet on a line with eyes open and closed, standing on a line with one foot with eyes open and closed, standing on a balance beam on one leg with eyes open and closed and standing heel to toe on a balance beam. These tests will be administered no more than two times with a maximum score of 10 seconds. Two additional subtests include walking forward on a line and walking heel to toe on a line for a maximum of 6 steps for both tasks. Total time to complete this test is approximately 10-20 minutes.
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Verbal Numeric Pain Scale
Description: The verbal numeric pain scale will be administered before and after each yoga session. The principal investigator (PI) will ask the participant about his/her pain on a scale of 0-10 and the PI will record the number. This will take less than 10 seconds.
Study NCT02473523 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: :Yoga Therapy
Description: Those who consent will participate in 60-minute yoga sessions 2-3 times per week for 4-6 weeks. Only specified yoga poses will be implemented during the classes. Additional detail is included in the Description sections of this registration. The principal investigator is a Certified Yoga Therapist (CYT) and is a registered yoga teacher with 500 hours of training (RYT 500).
Study NCT04038424 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Art therapy
Description: Art therapy including coloring, painting and listening to music
Study NCT03673566 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: NICU Dashboard
Description: The NICU Dashboard is displayed on a touch screen display mounted to the wall or on a rolling cart that will be placed near the bedside. The Dashboard will integrate information from various hospital/device sources in order to provide clinicians with one location to access and collectively interpret clinical findings and environmental factors. Parents will have their own view on the Dashboard that will allow them view their baby's progress, view educational materials, and have access to other resources at their fingertips.
Study NCT00916760 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Depigoid Parietaria judaica 1000DPP/ml
Description: Subcutaneous monthly treatment
Study NCT04638738 — intervention group
Intervention type: DEVICE
Intervention: SensiumVitals wearable patch sensor
Description: Wearable sensor which measures heart rate, respiratory rate, and temperature continuously.