AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03577158 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Closed-loop controller without exercise mitigation module
Description: On the second arm, participants will receive Sliding Mode Reference Conditioning (SMRC) Closed-loop insulin administration without a mitigation mode, based on subcutaneous continuous glucose monitoring (Second arm, Closed-loop study without mitigation module).~Commercial insulin infusion systems and continuous glucose monitoring devices will be used.
Study NCT02506647 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Gan & Lee insulin glargine followed by Lantus
Description: 0.4 IU/kg Gan \& Lee insulin glargine injection SC, Lantus 0.4 IU/kg injection SC
Study NCT02506647 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Lantus followed by Gan & Lee insulin glargine
Description: Lantus 0.4 IU/kg injection SC, 0.4 IU/kg Gan \& Lee insulin glargine injection SC,
Study NCT00780026 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: insulin
Description: bolus or infusion 80 to 110 mg/dl
Study NCT02417090 — intervention group
Intervention type: DRUG
Intervention: Insulin
Description: Pregnant women who used insulin to treat gestational diabetes
Study NCT02417090 — intervention group
Intervention type: DRUG
Intervention: Metformin
Description: Pregnant women who used metformin to treat gestational diabetes
Study NCT03213756 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Isometric exercises using Hand grip and elastic bands
Description: * Isometric exercises using hand-grip. This exercise consists of two sets of 30 hand-grip contractions with the hand of the upper arm candidate for AVF (in case of doubts about the most appropriate arm for AVF the exercise will be performed with both arms). The patient will rest one minute every 10 contractions and 5 minutes between both sets. The patient will repeat this protocol twice a day, morning and night (Approximately 15 minutes each session). The contraction intensity will start with half of the maximum force obtained by dynamometry and will be increased or decreased to be placed on an effort intensity 2-3 in the Borg scale.~* Isometric exercise using elastic bands. At noon the patient will perform a slow contraction session using elastic band with 20 slow repetitions with the arm in flexion and 20 repetitions with the arm in extension. (Total duration: less than 10 minutes)
Study NCT01875575 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT01875575 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Glucose 25g
Study NCT01875575 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Glucose 10g
Study NCT01022788 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Home-based counselling
Study NCT03577158 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Open-loop insulin infusion system
Description: Standard subcutaneous insulin infusion based on the individual insulin sensibility. Commercial insulin infusion systems and continuous subcutaneous glucose monitoring devices will be used.
Study NCT03577158 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Open-loop insulin infusion system
Description: Standard subcutaneous insulin infusion based on the individual insulin sensibility. Commercial insulin infusion systems and continuous subcutaneous glucose monitoring devices will be used.
Study NCT04340128 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Meglumine antimoniate
Description: Intra-lesional injection once a week, 0.1/cm2
Study NCT04340128 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Meglumine antimoniate
Description: Intra-lesional injection twice a week, 0.1/cm2
Study NCT04041765 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: IgM-enriched IVIG
Description: Contains human plasma protein 50mg/ml. With composition of Immunoglobulin M (IgM) 6mg, Immunoglobulin A (IgA) 6mg, Immunoglobulin G (IgG) 38mg (IgG subcl. approx. 63 % IgG1, 26 % IgG2, 4 % IgG3 and 7 % IgG4), Glucose monohydrate, sodium chloride, water for injections
Study NCT04041765 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: IgM-enriched IVIG
Description: Contains human plasma protein 50mg/ml. With composition of Immunoglobulin M (IgM) 6mg, Immunoglobulin A (IgA) 6mg, Immunoglobulin G (IgG) 38mg (IgG subcl. approx. 63 % IgG1, 26 % IgG2, 4 % IgG3 and 7 % IgG4), Glucose monohydrate, sodium chloride, water for injections
Study NCT01684566 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: episil(R)
Description: episil® is a lipid-based liquid that spreads onto mucosal surfaces and transforms into a protective, strongly bioadhesive FluidCrystal® film after intraoral administration.
Study NCT01684566 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Oral hygiene procedures
Description: Oral hygiene by using toothbrush, toothpaste, lip balm and dental floss (if available)
Study NCT01684566 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Oral hygiene procedures
Description: Oral hygiene by using toothbrush, toothpaste, lip balm and dental floss (if available)
Study NCT03007654 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Mediclore
Description: apply medical device fully around intrauterine surgery area
Study NCT03007654 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Adept
Description: apply medical device fully around intrauterine surgery area
Study NCT02408666 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Interview
Study NCT00026104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: gemcitabine hydrochloride
Description: Given IV
Study NCT00026104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: paclitaxel
Description: Given IV
Study NCT00026104 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: tipifarnib
Description: Given orally
Study NCT00026104 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: radiation therapy
Description: Undergo radiation therapy
Study NCT00860314 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: external electrical cardioversion (with antero-posterior electrode position)
Description: external biphasic electrical cardioversion with step-up-protocol of 50-75-100-150-200 Joules if necessary with antero-posterior electrode position until restoration of normal sinus rhythm
Study NCT00860314 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: external electrical cardioversion (with antero-lateral electrode position)
Description: external biphasic electrical cardioversion with step-up protocol of 50-75-100-150-200 Joules if necessary with antero-lateral electrode position until restoration of normal sinus rhythm
Study NCT02851290 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Caudal block anesthesia
Description: After induction of general anesthesia, a caudal block will be performed using 0.75-1 mL/kg of 0.2% ropivacaine without epinephrine
Study NCT02851290 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Dorsal penile nerve block anesthesia
Description: After induction of general anesthesia, a dorsal penile nerve block will be performed using 0.75-1 mL/kg of 0.2% ropivacaine without epinephrine
Study NCT04145908 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: midline mesh reinforcement
Description: augmentation of midline closure by nonabsorbsble mesh
Study NCT00600197 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: back school
Description: A kind of educational program for low back pain
Study NCT02368847 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Diagnostic tests
Description: C Reactive Protein (CRP) measurement on capillary blood using a point-of-care test to determine C Reactive Protein level in the blood
Study NCT02368847 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Diagnostic tests
Description: Uricult dipslide: Easy-to-perform bacterial culture test for dectecting urinary tract infections in point of care settings
Study NCT02354300 — intervention group
Intervention type: DEVICE
Intervention: TCD Ultrasound
Description: Transcranial doppler ultrasound monitoring will occur during flow diverter placement.
Study NCT03537781 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Food labelling versus no food labelling
Description: Food labelling availability and satiety status
Study NCT04224090 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Echocardiographic assessment of coronary arteries origin and proximal course
Description: Echocardiographic assessment of CAA utilizing 4 specific echocardiographic acoustic windows: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views.
Study NCT01987622 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: The patients in this group will receive individualized acupuncture prescribed by a certified Korean Medicine Doctor (KMD) with at least three years of clinical experience. The acupuncture formulas will be determined based on the individual patient's symptoms and at the KMD's discretion. The acupuncture treatment will be applied one to three times a week for six weeks (a total of 12 sessions and an additional four sessions are allowed). Acupuncture will be manually stimulated at first, and then electrical stimulation will be allowed at the KMD's discretion. Retention time will be equal to or less than 20 minutes. Examples of acupuncture points to be used might include LI4, LI11, TE5, SI3, TE3, ST36, SP6, SP9, LR3, GB34, Gb39, BL40, BL57, EX-B2, and BL23.
Study NCT01987622 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Usual care
Description: Usual care consists of patient education for a healthier lifestyle, including diet, exercise, self-management of symptoms, and the use of other treatments as needed. Participants will receive a three-page leaflet of patient education material. Optional regular physical therapies, including interferential current therapy (ICT) and local heat application, will be provided only for the control group at the participants' request . Physical therapy will be provided one to three times a week for six weeks (a total of 12 sessions and an additional four sessions are allowed). All kinds of conservative interventions for lumbar spinal stenosis, including analgesics and non-study physical treatments,will be allowed. However, surgical treatments, non-study acupuncture, or herbal medicine will not be allowed.
Study NCT01987622 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Usual care
Description: Usual care consists of patient education for a healthier lifestyle, including diet, exercise, self-management of symptoms, and the use of other treatments as needed. Participants will receive a three-page leaflet of patient education material. Optional regular physical therapies, including interferential current therapy (ICT) and local heat application, will be provided only for the control group at the participants' request . Physical therapy will be provided one to three times a week for six weeks (a total of 12 sessions and an additional four sessions are allowed). All kinds of conservative interventions for lumbar spinal stenosis, including analgesics and non-study physical treatments,will be allowed. However, surgical treatments, non-study acupuncture, or herbal medicine will not be allowed.
Study NCT03992287 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Hydrolysed Red Ginseng Extract
Description: 10 ml/day, 2.4g/day for 12 weeks
Study NCT03992287 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo for 12 weeks
Study NCT05053698 — intervention group
Intervention type: OTHER
Intervention: Aqueous flare measurement
Description: Aqueous flare was measured preoperatively and postoperatively with a laser flare-cell meter (LFCM ; Kowa FM-500, Kowa Company Ltd, Tokyo, Japan).
Study NCT01948505 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Intravenous acetaminophen
Study NCT01948505 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo for IV acetaminophen
Study NCT02829671 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Clinical and biological assessment
Description: Blood sample, clinical assessment with questionnaires
Study NCT03997747 — intervention group
Intervention type: OTHER
Intervention: cytology specimen
Description: Biopsy and Genetic: DNA analysis;Genetic: RNA analysis;Genetic: microarray analysis; Genetic: mutation analysis; Genetic: polymorphism analysis
Study NCT01477437 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Teens Taking Charge: Managing Hemophilia Online- Online self-management intervention
Description: The content will be delivered on a password-protected website, as part of the About Kids Health interface developed and maintained at the Hospital for Sick Children, Toronto, Canada. The website has been developed as eight discrete educational modules for adolescents. Each module takes approximately 30 to 45 minutes to complete. Content has been written and reviewed by experts from comprehensive hemophilia care clinics across Canada (physicians, nurses, physiotherapists and social workers) and edited by a medical writer to ensure that it is written at the suggested grade 6 reading level for patient education materials. Content has been written in English and will be translated into French prior to program launch. The format is geared towards adolescents and includes narratives with video components and interactive illustrations. In addition, each module will have quiz questions with real-time feedback to promote interactivity and knowledge retention.
Study NCT01977261 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Opening-wedge HTO
Description: Opening-wedge high tibial osteotomy fixated with a Puddu plate
Study NCT00405457 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Restasis, Optive Tears
Description: Restasis and Optive Tears use twice daily more frequently if needed
Study NCT04477421 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: FS-SMILE
Description: Femtosecond small incision lenticule extraction
Study NCT04477421 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: S-LASIK
Description: Femtosecond laser Insitu keratomileusis
Study NCT03160287 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Motivaltional interviews and infrequent motivational text messages
Description: A self-management intervention will integrate use of mobile technology to prompt older adults to be physically active, provides ongoing monitoring of the amount of their physical activity and includes self-efficacy enhancements is a novel non-pharmacological intervention both for prevention and treatment of sleep deficiency in persons with OA
Study NCT00390195 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RAD001 (everolimus)
Description: Arm 1: 2.5, 5, 7.5 or 10 mg of RAD001 daily
Study NCT00390195 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RAD001 (everolimus)
Description: Arm 2: 20, 30, 50 or 70 mg of RAD001 daily
Study NCT01991821 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: APD421
Study NCT01991821 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Study NCT02476955 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ 092 + carboplatin + paclitaxel (Closed)
Description: Subjects will receive ARQ 092 orally at dose levels specified for their respective dose cohorts plus carboplatin (AUC6, intravenously, Day 1) plus paclitaxel (175 mg/m2, intravenously, Day 1) on a 21-day schedule.
Study NCT02476955 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ 092 + paclitaxel (Closed)
Description: ARQ 092 will be administered orally at 200 mg twice a day (BID) weekly (Cohort 1P) of a 28-day cycle in combination with an intravenous (IV) infusion of paclitaxel (80 mg/m2). ARQ 092 will be administered once a week on Day 1, Day 8, Day 15, and Day 22 of each 28-day cycle; paclitaxel will be administered once a week on Day 1, Day 8, and Day 15 for three consecutive weeks followed by one week off of each 28-day cycle.
Study NCT02476955 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ARQ 092 + anastrozole
Description: ARQ 092 will be administered orally at 150 mg QD, 5 days on/9 days of a 28 day cycle in combination with anastrozole which will be administered orally at 1 mg QD continuously.
Study NCT02459223 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Nutritional biscuits and khichadi
Description: Nutritional biscuits and Khichadi.
Study NCT02459223 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Khichadi
Description: Khichadi.
Study NCT02410993 — intervention group
Intervention type: PROCEDURE
Intervention: CABG surgery
Study NCT01544959 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: fentanyl
Description: Use of esmolol and metoprolol compared to use of fentanyl for hemodynamic control during general anesthesia. At induction, fentanyl (2 mcg/kg) is replaced by esmolol (1 mg/kg). During the case, with a standardised anesthesia, response to surgical stimulation will be medicated either by fentanyl (50 mcg aliquot) or metropolol (2.5 mg), for a maximum of 6 doses. After this, fentanyl will be given unblindly.
Study NCT01544959 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: beta-blocker (esmolol, metropolol)
Description: esmolol is used at induction and lopressor during surgery instead of fentanyl in response to surgical stimulation.
Study NCT02382718 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: FAST fish mCyp c 1
Description: Subcutaneous immunotherapy
Study NCT02382718 — intervention group
Intervention type: BIOLOGICAL
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Subcutaneous immunotherapy
Study NCT04671433 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Genetic: AAV5-hRKp.RPGR
Description: Bilateral, sub-retinal administration of AAV5-hRKp.RPGR - immediate treatment group
Study NCT04671433 — intervention group
Intervention type: BIOLOGICAL
Group type: OTHER
Intervention: Genetic: AAV5-hRKp.RPGR
Description: No intervention - deferred treatment group (Bilateral, sub-retinal administration of AAV5-hRKp.RPGR to be administered in the follow-up study)
Study NCT01304121 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Bioactive glass (SP53P4)
Description: Commercial resorbable bone graft substitute (Vioxid Ltd)
Study NCT01140334 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Voucher Reinforcement
Description: Patients in this condition will be able to earn a voucher for each week that they have attended all scheduled psychiatric sessions. These sessions may include individual therapy appointments, group therapy appointments, or psychiatrist appointments. Each voucher will be worth $25, and can be exchanged for goods and services that will be purchased by a research assistant. The maximum amount of voucher earnings over the study is $300.
Study NCT02864342 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Arm 1: BreatheMate device with application
Description: The service known as 'BreatheMate' is a patient support tool that monitors daily Symbicort inhaler use. The BreatheMate service includes a bluetooth monitoring device that is attached to subjects' Symbicort pMDI inhaler which automatically detects and logs their maintenance medication use. Subjects will receive audio-visual daily reminders (beeps and flashes) on the BreatheMate Bluetooth device. The bluetooth device transmits this data to a cellular phone that is provided to all subjects in the study. Subjects in the intervention group will also receive audio-visual alerts (beeps, flashes) from the bluetooth device to take their medication.
Study NCT02864342 — intervention group
Intervention type: DEVICE
Group type: PLACEBO_COMPARATOR
Intervention: Arm 2: BreatheMate device without application
Description: The service known as 'BreatheMate' is a patient support tool that monitors daily Symbicort inhaler use. The BreatheMate service includes a bluetooth monitoring device that is attached to subjects' Symbicort pMDI inhaler which automatically detects and logs their maintenance medication use. The functionality of audio-visual daily reminders (beeps and flashes) is deactivated for this control group.~The BreatheMate service also includes a cellular phone that will display whether the Bluetooth monitoring device is paired and communicating with the cellular phone. The Bluetooth device will transmit data regarding medication usage to the cellular phone.
Study NCT01140334 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Standard Control
Description: Patients assigned to this condition will be treated at ATS for psychological problems. They will be scheduled to participate in individual therapy sessions with a psychiatrist and with their substance abuse counselor. They will also be referred to attend group therapy one time per week. No voucher incentive will be offered in this condition.
Study NCT04176341 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: a systematic proposal for non pharmacological interventions targeting the subject's empowerment among slackline, mindfulness, adapted physical activity, self-hypnosis, and Qi Gong
Description: chronic pain patient consulting in Grenoble Alps University Hospital, and Hospital Mutualist Group who will one non pharmacological intervention between slackline, mindfulness, adapted physical activity, self-hypnosis, Qi Gong during 6 to 8 weeks.
Study NCT02993887 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Resourcefulness Training
Description: This intervention will include a one time face to face instruction on Resourcefulness Training that entails 8 self-help and help-seeking skills plus viewing short video vignettes of caregivers describing application of the resourcefulness skills. In addition, participants will use daily journaling to describe application of the resourcefulness skills in their daily caregiving with their technology-dependent child.