AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03083028 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open reduction internal fixation of the ankl
Description: The specific procedure for each patient managed operatively, both in the observational study and the RCT, will be determined by the operating surgeon. Any adverse intra-operative or post-operative event will be recorded. This includes but is not limited to death, infection and neurovascular injury. Post operatively, all patients will be NWB (non weight bearing) and placed in a POP (plaster of paris) below knee cast or walking boot. Discharge from hospital will be determined by the patient walking 25m unaided by standby assistance. The treating surgeon will review the patients after 10-14 days for a wound review, removal of sutures and change of cast to a fibreglass cast or walking boot (cam walker). The patient will be WBAT (weight bearing as tolerated) for a further 4 weeks.
Study NCT00626093 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Cardiac Resynchronization Therapy - Defibrillator (CRT-D)
Description: * Patients in the study who receive Cardiac Resynchronization Therapy - Defibrillator (CRT-D) are indicated for Cardiac Resynchronization Therapy (CRT).~* Patient undergoes Defibrillation threshold (DFT) testing at implant and at 6 months. Defibrillation threshold (DFT) testing will include 3 ventricular fibrillation (VF) inductions.
Study NCT03708055 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Exercise Intervention
Description: Undergo weight bearing exercise program
Study NCT02396810 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: intra-operative MRI
Description: Intra-operative magnetic resonance imaging under general anesthesia
Study NCT02396810 — intervention group
Intervention type: PROCEDURE
Group type: PLACEBO_COMPARATOR
Intervention: Transsphenoidal resection of pituitary macroadenoma
Description: Routine transsphenoidal resection of pituitary macro adenomas
Study NCT02396810 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Transsphenoidal resection of pituitary macroadenoma
Description: Routine transsphenoidal resection of pituitary macro adenomas
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: DPP-4 inhibitors
Description: Current exposure to DPP-4 inhibitors (ATC A10BH, A10BD07-A10BD13) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: GLP-1 analogs
Description: Current exposure to GLP-1 analogs (ATC A10BX04, A10BX07) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Insulins
Description: Current exposure to insulin (ATC A10A) will be defined as any use of insulin between base cohort entry and the index day.
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Biguanides
Description: Current exposure to biguanides (ATC A10BA) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Sulfonylureas
Description: Current exposure to sulfonylureas (ATC A10BB or A10BC) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT03216434 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: MRI using DaTscan
Description: A standard, non-contrast-enhanced structural/anatomic brain MRI will be performed. It will be used to exclude potential subjects and controls with significant and potentially confounding structural/anatomic findings. It will also be used as an anatomic overlay with the functional DaTscan image to aid in anatomic/physiologic correlation. At the same imaging session, a brief functional MRI (not requiring the subject to perform any tasks) will also be performed.
Study NCT02500056 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Optilene LP mesh
Description: Lichtenstein hernioplasty
Study NCT02500056 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Ultrapro mesh
Description: Lichtenstein hernioplasty
Study NCT02760225 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: 89Zr-Pembrolizumab
Description: In part A of the imaging trial, a dose finding imaging study will be performed to assess the optimal tracer protein dose of 89Zr-pembrolizumab and the optimal interval between tracer injection and scanning. Approximately 3 cohorts of about 2-3 patients each will undergo 89Zr-pembrolizumab-PET imaging before start of treatment with pembrolizumab. In part B, 12 eligible patients will undergo 89Zr-pembrolizumab-PET imaging at baseline, with the optimal tracer protein dose and scanning schedule as determined in part A.
Study NCT02760225 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: 89Zr-Pembrolizumab PET
Description: In part A of the imaging trial, a dose finding imaging study will be performed to assess the optimal tracer protein dose of 89Zr-pembrolizumab and the optimal interval between tracer injection and scanning. Approximately 3 cohorts of about 2-3 patients each will undergo 89Zr-pembrolizumab-PET imaging before start of treatment with pembrolizumab. In part B, 12 eligible patients will undergo 89Zr-pembrolizumab-PET imaging at baseline, with the optimal tracer protein dose and scanning schedule as determined in part A.
Study NCT04228159 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Balance Tutor Biofeedback Rehabilitation System
Description: Balance Tutor system is a unique technology which allows for several postural control ability assessments as well as reactive response training in both standing and walking using controlled perturbation in simple task or multitask performance. Together with proactive training the system allows for optimal rehabilitation outcome and recovery
Study NCT04228159 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Balance and strengthening exercise
Description: exercise training programs for fall prevention including walking and balance exercises, functional tasks, strength, flexibility and endurance
Study NCT02720354 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: [11C]-DMDPA
Study NCT03816709 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Therapeutic Ultrasound
Description: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes.
Study NCT04158843 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Radical resection
Description: Radical resection is performed, and the cutting edge is negative.
Study NCT04158843 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radical radiotherapy
Description: Radical local radiotherapy is feasible (cumulative radiotherapy dose is greater than or equal to 50Gy).
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Thiazolidinediones
Description: Current exposure to thiazolidinediones (ATC A10BG) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT04158843 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Palliative treatment
Description: Including palliative internal fixation, radiotherapy, systemic chemotherapy, endocrine therapy or targeted therapy
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Alpha-glucosidase inhibitors
Description: Current exposure to alpha-glucosidase inhibitors (ATC A10BF) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index day.
Study NCT02456428 — intervention group
Intervention type: DRUG
Intervention: Meglitinides
Description: Current exposure to meglitinides (ATC A10BX02, A10BX03) will be defined as a prescription duration plus a 30-day grace period (to account for non-adherence and the biological half-lives of these drugs) that overlaps with the index (event)day.
Study NCT00911989 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: NOTES toolbox
Description: Using SFT for endoscope access during Transvaginal Sleeve Gastrectomy procedure. Visualization will occur through endoscope
Study NCT00214123 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: radiation therapy (radiotherapy)
Description: Bin assignment based on tumor volume
Study NCT02811874 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: diabetes education
Description: Diabetes education program includes: 4 theoretical sessions, 60 minutes long, taught once a week for 4 weeks, developed in the form of group classes, and given by one of the authors. The educational program content comprises (1) definition of diabetes, and identification of modifiable risk factors for type 2 diabetes, (2) non-pharmacological treatment, with emphasis on diet and exercise, (3) pharmacological therapy, including mechanism of action and side effects of anti-diabetic medications provided by the Brazilian public health system and (4) an overview of chronic diabetes complications.
Study NCT04761211 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: smart bra
Description: This is a patented infrared breast examination bra
Study NCT02025296 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: U-healthcare
Description: use of a public switched telephone network (PSTN)-connected glucometer to measure their blood glucose level at the same frequency as the SMBG group
Study NCT02007707 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Tobacco LHW
Description: Quit Smoking For a Healthy Family - This is a family-based psycho-education intervention using lay health worker (LHW) outreach. LHW will be trained to recruit smoke-family dyads and provide education and information about tobacco and health, and smoking cessation resources through 2 small-group education sessions and 2 individual phone calls over a 2-month period.
Study NCT02007707 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Healthy Eating
Description: Eating Healthy and Physically Active for You and Your Family - This is a attention-control comparison group using a family-based psycho-education intervention delivered through lay health worker (LHW) outreach. LHW will be trained to recruit smoke-family dyads and provide education and information about healthy eating and physical activity through 2 small-group education sessions and 2 individual phone calls over a 2-month period. Participants will receive writing information about smoking cessation resources.
Study NCT02811874 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: education in other areas
Description: Four theoretical sessions related to education in other health areas, not related to diabetes, administered during 4 weeks
Study NCT01298908 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Operative treatment
Description: In operative treatment the great saphenous vein will be removed after flush ligation by femoral vein and stripping of the trunk.
Study NCT00217087 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Endoscopic Mucosal Resection
Description: Endoscopic mucosal resection at time of endoscopy if indicated.
Study NCT00217087 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Photodynamic Therapy
Description: Porfimer sodium 2mg/kg
Study NCT00911846 — intervention group
Intervention type: OTHER
Intervention: interview
Description: interview using questionnaires
Study NCT04525105 — intervention group
Intervention type: GENETIC
Intervention: SMAD2
Description: a family of structurally related cytokines
Study NCT03359876 — intervention group
Intervention type: DRUG
Intervention: Rivaroxaban (Xarelto, BAY59-7939)
Description: 15 mg, once daily
Study NCT03359876 — intervention group
Intervention type: DRUG
Intervention: Warfarin sodium
Description: Individually adjusted dose
Study NCT04696588 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Complex set of kinesiotherapy of cervical spine and delicate massage
Description: Intervention:- A complex neck therapy.Treatment comprises 10 sessions performed on consecutive working days, includes four parts.~1. Active exercises of the neck, 5 minutes, first demonstrated by the physiotherapist and next the patient performs them under supervision, 5 repetitions of each of the following: cervical flexion, rotation to the left and to the right, side bending to the left and to the right, torsion to left and right.~2. Massage of cervical interspinales muscles performed by therapist 3 minutes.~3. Post Isometric Relaxation (PIR) performed by physiotherapist. 15 minutes.~4. Active neck exercises - the same as mentioned in step 1. 5 minutes. Total duration of one treatment session is around 30 minutes.
Study NCT01450423 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Physical activity
Description: Participation in a 10-week supervised cardio exercise program two-three times a week. Each training session consists of 10 minutes of warm-up, 20 minutes treadmill run/walk and 30 minutes cycling. Heart rate (HR) is monitored during each session. Week 1-5: at least 15 minutes above 75% of HRmax in each session. Week 6-10: at least one session above 75% HRmax.
Study NCT00713362 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Video-assisted thoracoscopic surgery
Description: VATS for bullectomy and mechanical pleurodesis
Study NCT00713362 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: chest tube drainage
Description: Chest tube drainage for pneumothroax
Study NCT01055535 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Microplasmin
Description: 125 µg intravitreal injection
Study NCT02558374 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: AR-13324 Ophthalmic Solution 0.02%
Description: 1 drop once daily (QD), PM, OU
Study NCT02558374 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Timolol Maleate Ophthalmic Solution 0.5% BID
Description: 1 drop BID, AM/PM, OU
Study NCT02558374 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Placebo
Description: 1 drop QD, AM, OU
Study NCT04616469 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Root canal treatment using TruNaomy rotary files
Description: Trunatomy rotary files will be used for the process of cleaning and shaping of the root canal system
Study NCT04616469 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Root canal treatment using race rotary instruments
Description: Race rotary files will be used for the process of cleaning and shaping of the root canal system
Study NCT03906500 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: High schools High on Life
Description: The intervention consist of three main components.~Environmental factors of the school environment~The component targeting the high school environment consisted of two separate elements:~* Revision of school alcohol policy~* Appointment of coordinator(s) of student committees organizing events, where alcohol is sold, and student introduction committee.~Student component~The Student components consisted of three main elements:~* Online education for the student committees organizing events where alcohol is sold and the student introduction committee~* Pocket movie campaign competition~* Social norms campaign~Parent component~The parent component consisted of three separate elements:~* Parent Information Meeting~* Parent Information Folder~* Parent Information Website
Study NCT03208231 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: VRC01
Description: 40 mg/kg of VRC01 administered by subcutaneous injection.
Study NCT03208231 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Combination Antiretroviral Therapy (cART)
Description: All infants received non-study provided cART selected by their primary care provider and supplied through non-study sources (i.e., cART not provided through the study).
Study NCT03208231 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Combination Antiretroviral Therapy (cART)
Description: All infants received non-study provided cART selected by their primary care provider and supplied through non-study sources (i.e., cART not provided through the study).
Study NCT02154087 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: HP802-247
Description: 260 µL (130 µL, one spray, of each component) containing 0.5 x 10.6 cells per mL, alternating weekly with Vehicle
Study NCT03354182 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Open flap surgery
Description: Elevation of a flap in order to access the treated furcation
Study NCT03354182 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bio-oss collagen
Description: Biomaterial for periodontal surgery
Study NCT03354182 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Bio-gide
Description: Biomaterial for periodontal surgery
Study NCT01724528 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Febuxostat
Description: Standard dose PO (per os) from Day 1 to Day 7 (can be continued up to DAY 9 at investigator's discretion)
Study NCT01724528 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Allopurinol
Description: Standard dose, low dose or high dose (as per investigator's judgement at the time of randomization) from DAY 1 to DAY 7 (can be continued up to DAY 9 at investigator's discretion)
Study NCT05153057 — intervention group
Intervention type: OTHER
Intervention: Observational study
Description: The goal of the study is purely observational. Treatment decisions will be made by physicians according to the grading of the intraocular inflammation related to birdshot chorioretinopathy and to their consequences on visual function. These treatment decisions will be independent from the observational study.
Study NCT02474329 — intervention group
Intervention type: OTHER
Intervention: Clinical assessment
Description: During the 13 week follow-up, trained physiotherapists will perform a standardized clinical assessment, based on the PPMI protocol (www.ppmi-info.org) for every included patient. This assessment will last for 60 minutes, and it will be done once.
Study NCT02474329 — intervention group
Intervention type: DEVICE
Intervention: Fox Insight self-monitoring android app and falls detector
Description: Patients will be asked to wear a smartwatch and a pendant movement sensor, both with triaxial accelerometers, during day and night, for a period of 13 weeks. Additionally, a self-monitoring App on a Smartphone is used, where the patient reports when (s)he takes any PD medication. An additional, optional button allows the patient to report general feeling.
Study NCT00183690 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Prolonged Exposure Therapy
Description: Prolonged exposure therapy includes a trauma focused protocol and cognitive behavioral treatment for PTSD. Cognitive behavioral treatment includes psychoeducation, in vivo exposures, and imaginal exposures.
Study NCT00183690 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Active Psychotherapy
Description: Active psychotherapy includes non-trauma focused therapy, based on time-limited psychodynamic treatment, which includes a formulation of a central issue and open-associative sessions exploring main conflicts and drives.
Study NCT03213873 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: HiBalance
Description: Intervention of highly challenging balance training for 10 weeks.
Study NCT01298908 — intervention group
Intervention type: PROCEDURE
Group type: OTHER
Intervention: Laser ablation
Description: In intravenous laser treatment a thin laser fiber is inserted through a tiny distal entry point. The probe is guided into place using ultrasound and the procedure is performed under local tumescence anesthesia. Laser energy is delivered to seal the faulty vein.
Study NCT03213873 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Speech and communication therapy
Description: Intervention conducted by speech and language therapist for 10 weeks.
Study NCT01106846 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Group A: Saline Group
Description: Saline continuous infusion
Study NCT01106846 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Group B: 1% Ketamine group
Description: Administration of 1% ketamine intravenously.
Study NCT00931216 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Integrated ANC, PMTCT, HIV services
Description: Of the 12 study clinics, 6 will be randomized to receive the intervention. At these 6 facilities, health care providers within the ANC department will be trained to also provide HIV/PMTCT care. Women testing positive within ANC clinics at integrated facilities will receive ANC, PMTCT and HIV services within the same visit/same service provider rather than being referred for HIV care and treatment.
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: asparaginase
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cyclophosphamide
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cytarabine
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: daunorubicin hydrochloride
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dexamethasone
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: doxorubicin hydrochloride
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: mercaptopurine
Study NCT00002744 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: methotrexate