AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03239600 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Placebo solution will be administered by IV infusion.
Study NCT03239600 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Methotrexate
Description: MTX dose between 7.5 to 15 mg will be administered in tablet form once in a week till last dose of GSK2618960 to all subjects in Part I and Part II.
Study NCT03239600 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Methotrexate
Description: MTX dose between 7.5 to 15 mg will be administered in tablet form once in a week till last dose of GSK2618960 to all subjects in Part I and Part II.
Study NCT01927627 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: enzalutamide
Description: oral therapy with enzalutamide at 160mg (4 capsules) orally once daily (QD).
Study NCT03090438 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Varicocele embolization
Description: Ultrasound guided right internal jugular vein access with placement of a vascular sheath. Fluoroscopically guided selective catheterization of the left and right (if bilateral) spermatic veins to the level of the inguinal ligament. Occlusion of the spermatic vein(s) by embolization coils and a sclerosing agent (sodium tetradecyl sulphate 3%).
Study NCT02212470 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Drug Eluting Balloon Angioplasty
Description: Angioplasty with Drug eluting balloon after pre dilatation
Study NCT02212470 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Nitinol stenting
Description: Nitinol stent deployment
Study NCT04197531 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Irrigation Method
Description: Irrigation Method
Study NCT00384254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 5 A
Description: Dental providers are trained to provide Ask, Advise, Assess, Assist and Arrange to all tobacco using patients. Written materials are provided, including information on local cessation resources, pharmacotherapy and tobacco quitlines.
Study NCT00384254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: 3 A
Description: Providers are trained to provide Ask, Advise and Arrange intervention to all tobacco using patients. Written materials, prescription for NRT and a Fax-to-Quit referral are provided.
Study NCT04203810 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Ectoin® Mouth and Throat Spray Althaea Honey (ERS09)
Description: 4 puffs to be administered as needed several times a day for patients aged ≥ 12 years. A maximum of 10 applications per day should not be exceeded.
Study NCT04203810 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: EMSER® Hals-und Rachenspray (throat spray)
Description: 1 to 3 puffs to be administered several times a day
Study NCT00586651 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: lestaurtinib
Description: 60 mg bid - 120 mg bid for an 18 weeks (126 days) treatment duration
Study NCT03576495 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: PACTS curriculum
Description: The cultural dexterity curriculum, known as PACTS (Provider Awareness Cultural Dexterity Toolkit for Surgeons) focuses on developing cognitive skills to adapt to individual patients' needs to ensure personal, patient-centered surgical care.~The curriculum is comprised of four educational modules on establishing trust in the physician-patient relationship, communicating effectively with patients with limited English proficiency, discussing informed consent, and issues surrounding pain management. Each module consists of an independent learning activity, an interactive role-play, and a post-lesson assessment.
Study NCT03576495 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Standard Residency Curriculum
Description: The standard residency curriculum consists of previously scheduled resident didactic sessions at all academic medical centers that may or may not include topics on cultural competency or cross-cultural care.
Study NCT04016883 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Problem Solving Therapy offered through a web platform
Description: Problem Solving Therapy offered through a web platform. There will be four sessions, during the first four weeks of treatment, and subsequent sessions are dedicated to refining problem-solving skills. Participants set treatment goals; different ways to reach goals are discussed and evaluated; action plans are created, and its effectiveness is evaluated to achieve the objectives. Participants are expected to implement plans and apply the problem-solving model to additional problems between sessions. In the last two sessions, participants create a relapse prevention plan using the problem-solving therapy model.
Study NCT04016883 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Conventional web platform
Description: The conventional web platform, which will contain the general content on stress coping techniques.
Study NCT04229446 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Music based caregiving
Description: The intervention (MBC) consists of daily individualized prerecorded music integrated with activity with about 30 minutes duration, combined with a one hour active session in groups twice weekly. The music will be selected based on individualized preferences from the patients or their family. The music will also be adapted to the day rhythm; awakening in the morning, support activities during the day, or for sleep in the evening. The healthcare worker will bring playback equipment e.g. a CD-player to the patient room. In addition will two weekly sessions in groups be performed (each on one hour) with music and movement.
Study NCT03801304 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Atezolizumab
Description: Atezolizumab in IV infusions
Study NCT03801304 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vinorelbine
Description: Vinorelbine capsules
Study NCT03684161 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: Cardiopulmonary function
Description: Body composition measurements; Pulmonary function tests; Cardiopulmonary exercise test; Force frequency releationship, ultrasound
Study NCT04473443 — intervention group
Intervention type: OTHER
Intervention: FEops HEARTguideTM
Description: A patient-specific computer simulation that aims to improve the outcomes after TAVI by suggesting THV platform, THV size and implantation depth with the use of the pre-procedural CT-scan.
Study NCT05057585 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Turning in bed, arm and leg exercises
Description: Exercises (arm and leg exercises, turning in bed) were applied only to the experimental group. It was applied for 15 minutes 12-24 hours before the operation.
Study NCT01617681 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VAL489
Description: Valsartan 3mg/kg oral solution
Study NCT01617681 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: VAL489 matching placebo
Description: Valsartan 3 mg/kg oral solution
Study NCT04838691 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: interpersonal counseling
Description: In the intervention group, it will be administered for 40 minutes for 8 weeks to people with symptoms of premenstrual syndrome.
Study NCT04475185 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MakAir
Description: MakAir artificial ventilator
Study NCT03081910 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Autologous CD5.CAR/28zeta CAR T cells
Description: Three dose levels will be evaluated:~Dose level one: 1×10\^7 cells/m2~Dose level two: 5×10\^7 cells/m2~Dose level three: 1×10\^8 cells/m2
Study NCT03081910 — intervention group
Intervention type: GENETIC
Group type: EXPERIMENTAL
Intervention: Allogeneic CD5.CAR/28zeta CAR T cells
Description: Three dose levels will be evaluated:~Dose level one: 1×10\^7 cells/m2~Dose level two: 5×10\^7 cells/m2~Dose level three: 1×10\^8 cells/m2
Study NCT03120559 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: New Floss Holder - Gum Chucks
Description: Dental inter-proximal control with GumChucks floss holder
Study NCT03120559 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: New Floss Holder - Gum Chucks/SMS
Description: Dental inter-proximal control with GumChucks floss holder and receiving 16 SMS during first 4 months.
Study NCT02831244 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Agili-CTM
Description: Consenting individuals will be selected from the population of patients with osteoarthritis of the great toe examined by a participating investigator. Following signing an informed consent, candidates will be evaluated by an adjudication committee for possible inclusion in the trial based on medical history and Standing Foot X-ray. Candidates that are approved or conditionally approved by the adjudication committee will undergo Agili-CTM implantation procedure
Study NCT02108782 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: dovitinib lactate
Description: Given PO
Study NCT02108782 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: pharmacological study
Description: Correlative studies
Study NCT02108782 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: laboratory biomarker analysis
Description: Correlative studies
Study NCT05576675 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: sufentanil + nalbuphine
Description: sufentanil 100 μ g + nalbuphine 40 mg
Study NCT05576675 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Sufentanil
Description: sufentanil 200 μ g
Study NCT05576675 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: hydromorphone + nalbuphine
Description: hydromorphone 10 mg+ nalbuphine 40 mg
Study NCT05868759 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Roentgen Stereophotogrammetric Analysis (RSA)
Description: Roentgenstereophotogrammetric analysis (RSA) is a radiographic technique, highly accurate both to evaluate the primary stability of the implant, then the micromovements between bone and implant prosthetic, both for the evaluation of the kinematics of the prosthetic components. The RSA technique in dynamics is able to obtain, with patient in motion, a series of radiographic frames in sequence in two projections, which are captured simultaneously. Each pair of orthogonal projections corresponds to a specific moment of the movement carried out by the patient and will be used to obtain, through dedicated software, a reconstruction three-dimensional instant defined RSA scenes.
Study NCT05868759 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Delos Postural Proprioceptive System (computerized oscillating platform)
Description: The Delos Postural Proprioceptive System uses electronic tilting tables (on a single axis or three axes) with high frequency that allows very short stop and reversal times that allow both to study the proprioception and the patient's response to the modification of movement of the inclined plane
Study NCT05868759 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: Modified Star Excursional Balance Tests
Description: The Star Excursional Balance Test (SEBT) is a clinical test designed for the evaluation of dynamic physical performance of the tibiotarsica. The first literary references date back to 1998 and the test, remaining in balance with the ankle in the studio, the achievement of the maximum possible distance with the contralateral foot along well-defined axes.
Study NCT05868759 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Inertial sensors Xsens MVN
Description: The inertial motion acquisition system Xsens MVN is easy to use and economic to detect the movement of different anatomical districts. MVN is based on inertial sensors in miniature through communication solutions combined with advanced fusion algorithms sensors, using hypotheses of biomechanical models.~This MVN system is a system of inertial kinematic measurement of the whole body, which incorporates synchronized data. Instant graphic output is provided, including angles of motion articular.
Study NCT05868759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: American Orthopaedic Foot and Ankle Score (AOFAs)
Description: American Orthopaedic Foot and Ankle Score (AOFAs) is a clinical trial commonly used in scientific literature which serves to assess, in terms of value from 0 to 100, the autonomy, pain, stability, ankle alignment and back foot of the patient.
Study NCT05868759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Visual Analogue Scale (VAS)
Description: The Visual Analogue Scale (VAS) is a visual representation of the extent of pain that the patient subjectively warns. The VAS is represented by a 10 cm long line in the original version validated, with or without notches at each centimeter. One end indicates the absence of pain and corresponds to 0, the other end indicates the worst pain imaginable and corresponds to 10.
Study NCT05868759 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: 12-Item Short Form Survey (SF-12)
Description: The 12-Item Short Form Survey (SF-12) is a self-reported outcome measure assessing the impact of health on an individual's everyday life.
Study NCT03814473 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Diet
Description: Participants provided with a brochure providing a thorough description of the diet, \~8 example recipes for each meal (i.e. breakfast, lunch, dinner, and snacks) included as a sample menu, and guidance to assist in shopping and self-preparation of food for the prescribed diet and to improve adherence. Diet consisted of following the popular paleolithic diet
Study NCT00224848 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Palm-Pilot Intervention
Description: Both groups received guideline dissemination, patient activation materials, continuing education (CE) and feedback based on baseline chart audit. The intervention included academic detailing (AD) and a hand-held computerized decision support tool that provided patient-specific, ATPIII-based risk stratification and treatment recommendations. CE sessions offered information relevant to ATPIII and JNC7 and focused on the evidence base. AD offerings focused on strategies to apply concepts to practice and were specific to the randomized arm. Investigators visited each practice at baseline to educate physicians about the guideline and evidence supporting prevention of CVD, and to provide training on use of the Palm tool. Visits were conducted as lunch and learn sessions. The tool was a modified version of NHLBI's PDA decision support program and indicates specific drug therapies and dosages needed to achieve cholesterol reduction and prints documentation. A user's manual was developed.
Study NCT01864642 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: osteopathic manipulative treatment (OMT)
Study NCT01864642 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: osteopathic manipulative treatment (OMT)
Description: OMT is a form of manual medicine performed by osteopathic physicians
Study NCT00224848 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Palm-Pilot Intervention
Description: Both groups received guideline dissemination, patient activation materials, continuing education (CE) and feedback based on baseline chart audit. The intervention included academic detailing (AD) and a hand-held computerized decision support tool that provided patient-specific, ATPIII-based risk stratification and treatment recommendations. CE sessions offered information relevant to ATPIII and JNC7 and focused on the evidence base. AD offerings focused on strategies to apply concepts to practice and were specific to the randomized arm. Investigators visited each practice at baseline to educate physicians about the guideline and evidence supporting prevention of CVD, and to provide training on use of the Palm tool. Visits were conducted as lunch and learn sessions. The tool was a modified version of NHLBI's PDA decision support program and indicates specific drug therapies and dosages needed to achieve cholesterol reduction and prints documentation. A user's manual was developed.
Study NCT01090284 — intervention group
Intervention type: DEVICE
Intervention: Inguinal hernioplasty
Description: A conventional Prosthetic Inguinal Hernioplasty (Trabucco's Technique) will be performed by using polypropylene mesh.
Study NCT02004600 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Photodynamic therapy (PDT)
Description: 1 session of Photodynamic therapy (PDT) on epidermis dysplasia
Study NCT02155881 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ciclesonide
Description: Ciclesonide nasal spray 50 mcg/actuation
Study NCT02155881 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Ciclesonide Placebo
Description: Ciclesonide placebo-matching nasal spray
Study NCT00715455 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REG1
Description: ii. The REG1 anticoagulation system consists of a drug (RB006) and antidote (RB007). The drug (RB006) is administered via IV bolus to achieve anticoagulation. The antidote (RB007) is administered as an IV bolus dose at approximately 10% the total reversal dose followed by the remaining dose several hours later to counteract RB006 induced anticoagulation.
Study NCT00715455 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: REG1
Description: ii. The REG1 anticoagulation system consists of a drug (RB006) and antidote (RB007). The drug (RB006) is administered via IV bolus to achieve anticoagulation. The antidote (RB007) is administered as an IV bolus dose at 100% of the total reversal dose to counteract RB006 induced anticoagulation.
Study NCT00715455 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Unfractionated Heparin
Description: Heparin will be administered per standard of care at sites
Study NCT04357782 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: L-ascorbic acid
Description: 50 mg/kg L-ascorbic acid infusion given every 6 hours for 4 days (16 total doses)
Study NCT04143893 — intervention group
Intervention type: DEVICE
Intervention: Mechanical circulatory support
Description: Patients with cardiogenic shock who underwent MCS
Study NCT03949049 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Citicoline
Description: Citacoline as neuroprotector
Study NCT03949049 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: placebo group
Study NCT03704597 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: cryotherapy
Description: Cooling of oral mucosa
Study NCT03704597 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: cryotherapy
Description: Cooling of oral mucosa
Study NCT03764215 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nilotinib 150 MG
Description: 10 participants will receive an oral dose of 150mg Nilotinib once daily for 3 months (group 1). If this dose is tolerated another 10 participants will receive an oral dose of 300mg Nilotinib once daily (group 2) for 3 months.
Study NCT02531373 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: V114 Medium Dose
Description: 15-valent pneumococcal conjugate vaccine with serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19F, 19A, 22F, 23F, 33F (2 mcg each), serotype 6B (4 mcg) and Merck Aluminum Phosphate Adjuvant (125 mcg) in each 0.5 mL dose
Study NCT02531373 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: V114 High Dose
Description: 15-valent pneumococcal conjugate vaccine with serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19F, 19A, 22F, 23F, 33F (4 mcg each), serotype 6B (8 mcg), and Merck Aluminum Phosphate Adjuvant (250 mcg) in each 0.5 mL dose
Study NCT02531373 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: V114 Medium Dose with Alternative Carrier Protein
Description: 15-valent pneumococcal conjugate vaccine with serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19F, 19A, 22F, 23F, 33F (2 mcg each), serotype 6B (4 mcg), and Merck Aluminum Phosphate Adjuvant (125 mcg) with alternative carrier protein in each 0.5 mL dose
Study NCT02531373 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: V114 High Dose with Alternative Carrier Protein
Description: 15-valent pneumococcal conjugate vaccine with serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19F, 19A, 22F, 23F, 33F (4 mcg each), serotype 6B (8 mcg), and Merck Aluminum Phosphate Adjuvant (250 mcg) with alternative carrier protein in each 0.5 mL dose
Study NCT02531373 — intervention group
Intervention type: BIOLOGICAL
Group type: ACTIVE_COMPARATOR
Intervention: Prevnar 13™
Description: 13-valent pneumococcal conjugate vaccine with serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19A, 19F, 23F (2.2 mcg) and 6B (4.4 mcg) in each 0.5 ml dose
Study NCT01031758 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 3H-Cholesterol
Description: A single dose of 25-50 μCi 3H free cholesterol -albumin complexes (containing approximately 0.1 - 0.3 mg of cholesterol) will be administered intravenously as a slow bolus injection within 1-2 minutes.
Study NCT01563562 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Bardoxolone Methyl
Description: Oral, Single dose
Study NCT04099056 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: Neurostimulation
Description: Participants will be seated comfortably in a chair and asked to complete simple computer tasks. Participants will receive neurostimulation in the form of Transcranial Magnetic Stimulation (TMS) or Temporal Interference (TI).~TMS: Either during, or just before any of the tasks, participants will receive either repetitive transcranial magnetic stimulation (rTMS) or single pulse TMS. During this, the researchers place a small plastic coil next to the participant's head. The coil will then generate a magnetic pulse, and stimulation will occur during presentation of the visual stimuli on which subjects will conduct behavioral or cognitive tasks.~TI: Either during, or just before, any of the above tasks, participants will receive stimulation with TI. To do so, commercially available gel-based electrodes will be placed on the scalp to target the relevant brain region. The position targeted by the electrodes will be guided by previously defined coordinates.