AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ustekinumab IV Infusion
Description: Participants will receive a single IV infusion dose of ustekinumab (dosage to be decided based on body weight) on Day 8.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ustekinumab SC Injection
Description: Participants will receive a Ustekinumab 90 mg SC maintenance dose on Day 64. A second optional maintenance dose may be administered on Day 120 based on participants clinical response assessed by investigator.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Midazolam 2 mg
Description: Participants will receive 2 milligram per milliliter (mg/ml) syrup of midazolam as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Warfarin 10 mg
Description: Participants will receive 10 mg tablet of warfarin as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin K 10 mg
Description: Participants will receive 10 mg tablet of vitamin K as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT02164162 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Lokomat (Hocoma, Zurich, Switzerland)
Description: Patients allocated to the Experimental group performed a Robotic Assistested Gait Training by means of the Lokomat. The Lokomat is robotic device set up as an exoskeleton on the lower limbs of the patient. The system uses a dynamic body weight-support system to support he participant above a motorized treadmill synchronized with the Lokomat.
Study NCT02164162 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Conventional physical treatment
Description: Patients allocated to the Control Group performed a general exercise program and a conventional gait training. The general exercise program consisted in cardiovascular warm-up exercises, muscle stretching exercises, active-assisted or active isometric and isotonic exercises for the main muscles of the trunk and limbs, relaxation exercises, coordination and dual task activities and balance exercises. The conventional gait therapy was based on the proprioceptive neuromuscular facilitation (PNF) concept (lasting 30 minutes), with rhythmic initiation, slow reversal, and agonistic reversal exercises applied to the pelvic region, each 10 minutes long. The same trained therapist treated all the patients in this group and standardized the duration of each part of the treatment.
Study NCT03251404 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Injury prevention exercise programs
Description: The two intervention programs contain exercises aiming to increase lower extremity strength, core stability, balance and neuromuscular function.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Omeprazole 20 mg
Description: Participants will receive 20 mg capsule of omeprazole as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Dextromethorphan 30 mg
Description: Participants will receive 30 mg capsule of dextromethorphan as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT03358706 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Caffeine 100 mg
Description: Participants will receive 100 mg tablet of caffeine as a component of the Cytochrome P 450 probe cocktail orally.
Study NCT03478683 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: placebo to match tiotropium
Description: Subjects will receive tiotropium matching placebo via Handihaler once daily in the morning
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: ELLIPTA
Description: Subjects will receive FF/UMEC/VI 100/62.5/25 mcg and matching placebo via ELLIPTA in the treatment period. Budesonide/formoterol plus tiotropium once daily plus placebo will be administered via ELLIPTA during the run-in period.
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ELLIPTA
Description: Subjects will receive FF/UMEC/VI 100/62.5/25 mcg and matching placebo via ELLIPTA in the treatment period. Budesonide/formoterol plus tiotropium once daily plus placebo will be administered via ELLIPTA during the run-in period.
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: MDI
Description: Subjects will receive budesonide/formoterol and placebo to match budesonide/formoterol via MDI in the treatment period.
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: MDI
Description: Subjects will receive budesonide/formoterol and placebo to match budesonide/formoterol via MDI in the treatment period.
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: HandiHaler
Description: Subjects will be administered tiotropium (18 mcg) or placebo to match tiotropium via HandiHaler during the treatment period.
Study NCT03478683 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: HandiHaler
Description: Subjects will be administered tiotropium (18 mcg) or placebo to match tiotropium via HandiHaler during the treatment period.
Study NCT01263028 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ergocalciferol supplementation
Description: Vitamin D in the form of ergocalciferol will be the drug utilized in the study. This medication is a Vitamin D analog and is normally used in the current study population to help augment those who are deficient in Vitamin D.
Study NCT04108260 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Albutrepenonacog Alfa 1 UNT [IDELVION]
Description: Clinical data will be collected from patients who suffered from hemophilia B, and switch from other FIX products to Idelvion as prophylaxis, prevention of bleeding (e.g. surgery) or treatment of bleeding.
Study NCT03888482 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Verofilcon A contact lenses
Description: Investigational daily disposable soft contact lenses
Study NCT04361110 — intervention group
Intervention type: RADIATION
Intervention: Computerized tomography scan of the abdomen
Description: Non-specific abdominal ct´s with different phases and contrast +/-.
Study NCT03888482 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: Somofilcon A contact lenses
Description: Commercially available daily disposable soft contact lenses
Study NCT02438085 — intervention group
Intervention type: OTHER
Intervention: prospective collection of data and follow-up
Description: prospective collection of data and follow-up of all patients admitted to hospital for ACS
Study NCT02510599 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: solithromycin
Study NCT02646436 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: HD treatment
Description: Patients with absolute contraindication to the PD method will be treated with HD. HD will be performed after implantation of central venous catheter using Seldinger technique by nephrology team.
Study NCT02646436 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: PD treatment
Description: Patients without absolute contraindication to the PD method will be treated with PD. PD will be performed after implantation of peritoneal catheter using Seldinger technique by nephrology team.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mattis Dementia Rating Scale
Description: This scale was developed to assess the cognitive status of patients with neurodegenerative diseases. There are 37 items that are presented in a fixed order and grouped into five sub-scales: attention, initiation, construction, conceptualization and memory. Patients and healthy subjects with a score below 125 are not included because of major cognitive impairment.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Unified Parkinson 's Disease Rating Scale-III
Description: This scale is used to rate the severity of extra-pyramidal symptoms (akinesia, rigidity and tremors). These symptoms may be the cause of reduction of motor activity apart from any reduction in motivation, they onstitute a confounding factor that it should be controlled.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Mini Neuropsychiatric Investigation
Description: This is a structured interview that allows rapid screening in about 20 minutes of troubles Psychiatric. It is based on short questions to which the patient must answer yes or no and on a decision tree. Patients must validate clinical diagnoses of depression.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Mini Neuropsychiatric Investigation
Description: This is a structured interview that allows rapid screening in about 20 minutes of troubles Psychiatric. It is based on short questions to which the patient must answer yes or no and on a decision tree. Patients must validate clinical diagnoses of depression.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Montgomery and Asberg depression Rating Scale
Description: This scale is composed of 10 items from 0 to 6 from a semi-structured interview, to obtain a total depression score of 0 to 60 (0 no depression, 60 maximum intensity of depression).
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Montgomery and Asberg depression Rating Scale
Description: This scale is composed of 10 items from 0 to 6 from a semi-structured interview, to obtain a total depression score of 0 to 60 (0 no depression, 60 maximum intensity of depression).
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Clinical Global Impression
Description: heterosexual assessment that rates the severity of symptoms suicidal and changes in suicidal symptoms. Any subject with a score greater than 4 is not included.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Clinical Global Impression
Description: heterosexual assessment that rates the severity of symptoms suicidal and changes in suicidal symptoms. Any subject with a score greater than 4 is not included.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Apathy diagnostic criteria
Description: The clinical criteria make it possible to make a diagnosis of apathy with a functional repercussion. It is based on a lack of motivation felt by the patient, causing a functional or social impact that is not the consequence of a disturbance of consciousness or a disability engine. The cognitive, emotional and behavioral dimensions are affected.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: walking speed test
Description: The patient is timed to walk 10m. A speed \<1m / sec is a criterion exclusion because it shows severe sarcopenia and constitutes a bias.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: accelerometer presentation
Description: accelerometer presentation and pose
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: accelerometer presentation
Description: accelerometer presentation and pose
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: data acquisition from the accelerometer
Description: withdrawal of the accelerometer and data acquisition from the accelerometer
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: data acquisition from the accelerometer
Description: withdrawal of the accelerometer and data acquisition from the accelerometer
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Apathy Evaluation Scale,
Description: clinician version and near-helping version. It's a hetero rating scale from an interview semi structured by a trained clinician. It assesses cognitive, emotional and behavioral apathy than three items of various apathy. The total score ranges from 18 (total absence of apathy) to 72.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: fatigue Visual Analog Scale
Description: To date, there is no valid fatigue scale in the depression of the elderly subject, a fortiori in French. The fatigue scale in adult depression includes has been validated with an EVA (Visual Analogue Scale) (38). We therefore propose to use this type of evaluation to control this aspect.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: executive function
Description: * Modified Card Sorting Test MCST(Modified Card Sorting Test) (Wisconsin Test): This test assesses conceptualization, attention and mental flexibility using a deck of cards.~* Trail Making Test (TMT): This test is used to assess mental flexibility.~* Fluences verbal: This test tests the capacities of setting up search strategies in memory semantics and oral language.~* Stroop Paradigm: This test is used to evaluate the resistance to interference, ie the patient's ability to inhibit some over-learned and automated responses.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: executive function
Description: * Modified Card Sorting Test MCST(Modified Card Sorting Test) (Wisconsin Test): This test assesses conceptualization, attention and mental flexibility using a deck of cards.~* Trail Making Test (TMT): This test is used to assess mental flexibility.~* Fluences verbal: This test tests the capacities of setting up search strategies in memory semantics and oral language.~* Stroop Paradigm: This test is used to evaluate the resistance to interference, ie the patient's ability to inhibit some over-learned and automated responses.
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: MRI
Description: An MRI lasting 30 minutes is programmed
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: MRI
Description: An MRI lasting 30 minutes is programmed
Study NCT03807167 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Apathy Motivation Index
Description: This is a self-questionnaire of 18 items, each side on a 5-level Likert scale (0: not everything at 4: very often). It differentiates between behavioral apathy and social apathy.~Emotional.
Study NCT00825175 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Treadmill Training
Description: Parents hold their infants on an infant treadmill for 8 minutes a day, 5 days a week. The treadmill speed is set at 0.2 m/s.
Study NCT00825175 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Treadmill Training
Description: Parents hold their infants on an infant treadmill for 8 minutes a day, 5 days a week. The treadmill speed is set at 0.2 m/s.
Study NCT00825175 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Supramalleolar Orthoses
Description: In addition to treadmill training the infants receive Supramalleolar orthoses. They wear the orthoses for 8 hours a day, 5 days a week.
Study NCT03657407 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Belladonna Opium
Description: Belladonna Opium 16.2-60mg rectal suppository
Study NCT03657407 — intervention group
Intervention type: DRUG
Group type: SHAM_COMPARATOR
Intervention: Glycerin Suppository
Description: Glycerine rectal suppository
Study NCT04958590 — intervention group
Intervention type: RADIATION
Intervention: whole spine X-ray
Description: Group 1 underwent whole spine X-ray in standing and sitting positions.
Study NCT03468946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: salty taste perception
Description: salty taste perception in high caries risk, medium caries risk, low caries risk.~The aim of this study was to evaluate salty taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors(high caries risk, medium caries risk, low risk ).
Study NCT03251404 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Injury prevention exercise programs
Description: The two intervention programs contain exercises aiming to increase lower extremity strength, core stability, balance and neuromuscular function.
Study NCT03468946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: bitter taste perception
Description: bitter taste perception in high caries risk, medium caries risk, low caries risk.~The aim of this study was to evaluate bitter taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).
Study NCT03468946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: sour taste perception
Description: sour taste perception in high caries risk, medium caries risk, low caries risk. The aim of this study was to evaluate sour taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).
Study NCT03468946 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: sweet taste perception
Description: sweet taste perception in high caries risk, medium caries risk, low caries risk.~The aim of this study was to evaluate sweet taste perceptions of school children and compare them with demographic, clinical, microbiologic and biochemical caries-risk factors (high caries risk, medium caries risk, low risk ).
Study NCT02366130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ra-223 dichloride
Description: 55 kBq/kg by vein on Day 1 of each 28 day cycle, and then every four weeks thereafter for 6 cycles.
Study NCT02366130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Denosumab
Description: 120 mg by subcutaneous (SC) injections on Day 1 of Cycles 2-5.
Study NCT02366130 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hormone Therapy
Description: A single hormonal agent administered daily while on study. Physician to decide what type of hormone therapy participant will receive.
Study NCT04201405 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Autologous CD34+ cells transduced with a lentiviral vector containing the human SGSH gene
Description: Autologous CD34+ haematopoietic stem cells from MPS IIIA patients will be genetically modified ex vivo using CD11b.SGSH Lentiviral vector (LV), a self-inactivating LV expressing the SGSH gene codon optimized for human use and regulated by a human CD11b myeloid-specific promoter. Cells will be cryopreserved prior to patient administration.
Study NCT04934774 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: CD7 CAR T cells
Description: Non-gene edited anti-CD7 CAR T cells administered to patients, will be either fresh or thawed CAR T cells by IV injection after receiving lymphodepleting chemotherapy.
Study NCT04063137 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Anthocyanin fortified bread with beef patty (35% fat)
Description: Bread is fortified at a 4% level using 25% (w/w) anthocyanin black rice extract. It is served with a beef patty (35% fat) to simulate a high-fat diet.
Study NCT04063137 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Anthocyanin fortified bread with beef patty (35% fat)
Description: Bread is fortified at a 4% level using 25% (w/w) anthocyanin black rice extract. It is served with a beef patty (35% fat) to simulate a high-fat diet.
Study NCT03512158 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Non-invasive respiratory support mode
Description: A mode of providing respiratory support via nasal masks or prongs
Study NCT02256774 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: BILR 355 BS
Study NCT03512158 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Non-invasive respiratory support mode
Description: A mode of providing respiratory support via nasal masks or prongs
Study NCT03947021 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Computed tomography (CT) scan
Description: A CT scan of thorax and heart will be performed in the CT+BSPM group.
Study NCT03947021 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Body-surface potential mapping
Description: Measurement of 256-lead body-surface electrocardiogram
Study NCT03306290 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: Serum dosage of antibiotic prophylaxis CEFOXITIN
Description: Three blood samples will be collected. These samples are specific for the research, and will be performed on the forearm opposite to the one used for Cefoxitin infusion.~1. Blood sample at the start of surgery (t0): at the end of the Cefoxitin infusion (\~30 min), 1 tube (5 ml) of blood will be withdrawn~2. Blood sample at half way surgery (t1): 1 tube (5 ml) of blood will be withdrawn (if applicable)~3. Blood sample at skin closure (t2): 1 tube (5 ml) of blood will be withdrawn
Study NCT02223130 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cognitive Behavioral Therapy techniques
Description: Participants attend 9 weekly group sessions. Each of the weekly sessions is led by a mental health professional and a peer facilitator who use Cognitive Behavioral Therapy techniques to work with participants in tracking their cognitions, emotions and behaviors in response to stressful/discrimination experiences.
Study NCT01217515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diltiazem hydrochloride 4% cream
Description: 3 times daily
Study NCT01217515 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Diltiazem hydrochloride 2% cream
Description: 3 times daily
Study NCT01217515 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: 3 times daily
Study NCT00362323 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: fenofibrate (F) + metformin (M) hydrochloride fixed combination
Description: F80mg/M500mg - per os - twice a day during 24 weeks / or / F80mg/M850mg - per os - twice a day during 24 weeks /or / F54mg/M850mg - per os - three times a day during 24 weeks
Study NCT00362323 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Metformin
Description: 500mg - per os - twice a day during 24 weeks /or / 850mg - per os - twice a day during 24 weeks /or / 850mg - per os - three times a day during 24 weeks