AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT01704339 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: QUTENZA
Description: Single treatment with topical capsaicin 8%
Study NCT04023006 — intervention group
Intervention type: DEVICE
Intervention: Removable prostheses
Description: Full dentures created by Additive manufacturing (Carbon Printers)
Study NCT02465229 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Multimodal tissue-sampling methods before and after stricture dilation
Description: Each participant will receive the following tissue-sampling methods in order : 1)intraductal suction, 2)intraductal forceps biopsy, 3)brushing cytology, 4)stricture dilation, 5)intraductal suction, 6)intraductal forceps biopsy and 7)brushing cytology during endoscopic retrograde cholangiopancreatography.
Study NCT01958151 — intervention group
Intervention type: OTHER
Intervention: State-Trait Anxiety Inventory Scores
Description: Patients are evaluated before the procedure with State-Trait Anxiety Inventory scores to determine the anxiety level.
Study NCT00793208 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: semi-allogeneic human fibroblasts (MRC-5) transfected with DNA
Description: Each vaccine consists of 1 x 10e7 DNA-transfected irradiated fibroblasts. A total of 4 weekly immunizations will be delivered to each patient. Each vaccine will be administered i.d. using a 1 mL syringe and a 25 gauge needle.~Subjects will have immunizations administered at 4 different sites for each vaccination as follows:~Site #1: Right arm Site #2: Left arm Site #3: Right thigh Site #4: Left thigh Approximately equal numbers of transfected fibroblasts will be administered at each site.
Study NCT00438516 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: nurse home visitation
Description: Nurse home visits from midway through pregnancy to child age 2
Study NCT03989817 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Vasoactive Intestinal Peptide (VIP) and Saline
Description: 12 healthy volunteers of both genders will be included in the main study. Participants will meet twice, with at least one week in between. The main study is a double-blind, randomized, cross-over trial among placebo (sterile saline, non-active substance) and VIP. Intravenous infusion of VIP / placebo (saline) will be conducted over 120 minutes. Patients will be asked after each trial day to record headache strength, accompanying symptoms, and drug use for up to 24 post-infusion.
Study NCT03989817 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vasoactive Intestinal Peptide (VIP) and Saline
Description: 12 healthy volunteers of both genders will be included in the main study. Participants will meet twice, with at least one week in between. The main study is a double-blind, randomized, cross-over trial among placebo (sterile saline, non-active substance) and VIP. Intravenous infusion of VIP / placebo (saline) will be conducted over 120 minutes. Patients will be asked after each trial day to record headache strength, accompanying symptoms, and drug use for up to 24 post-infusion.
Study NCT04638010 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Cancer control navigation (CNN)
Description: Cancer Control Navigators (CNNs) housed at 2-1-1 call centers aid callers. CNNs receive electronic summary profiles of participants assigned to navigation. Navigators call the participant, build a collaborative relationship with them, identify their needs, work with them to identify barriers to services and coordinate solutions, and provide logistic (e.g., making appointments) and emotional support. Navigation services are provided by telephone only.
Study NCT04638010 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: General referral (usual care)
Description: Information Specialists at the 2-1-1 call center provide cancer control referrals specific to participant's screening or prevention needs.
Study NCT04638010 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: General referral (usual care)
Description: Information Specialists at the 2-1-1 call center provide cancer control referrals specific to participant's screening or prevention needs.
Study NCT03594994 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Sleep extension
Description: Extend time-in-bed by one hour
Study NCT05274945 — intervention group
Intervention type: RADIATION
Group type: ACTIVE_COMPARATOR
Intervention: Radiotherapy
Description: radiotherapy 45 Gy/ 25 fractions then boost 5.4 Gy/3 fractions with concurrent bolus 5-fluorouracil
Study NCT05274945 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: Radiotherapy
Description: radiotherapy 45 Gy/ 25 fractions then boost 5.4 Gy/3 fractions with concurrent bolus 5-fluorouracil
Study NCT05274945 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: consolidation chemotherapy
Description: 6 cycles of FOLFOX or CAPOX
Study NCT05274945 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: TME or APR
Description: total mesorectal excision or abdominoperineal resection
Study NCT05274945 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: TME or APR
Description: total mesorectal excision or abdominoperineal resection
Study NCT01745263 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D3
Description: 2000 IU/d
Study NCT04155957 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Rapid Recovery Rehabilitation Programme
Description: Usual intervention at Hospital Clínic de Barcelona for post-operative rehabilitation of TKA patients. Participants, already at home after hospital discharge, must perform 5 different exercises 4 times a day (twice in the morning, twice in the afternoon).~Participants are also encouraged to walk and stretch their legs. Domiciliary visits by a physiotherapist start at approximately 2 weeks after the surgery to help participants do the exercises.
Study NCT04155957 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ReHub
Description: Participants use a telerehabilitation platform, ReHub, as a guide to perform the TKA rehabilitation exercises of the Rapid Recovery Rehabilitation Programme intervention.~The exercise plan in ReHub is carried out by a site physiotherapist on the first day after discharge by using ReHub to acquire the participant's movement pattern with a wearable inertial sensor that transmits data to the platform.~The wearable inertial sensor participants must wear tracks movement while they do the TKA rehabilitation exercises. Movement is analysed and feedback is given in real time. At the end of each exercise, participants can select if they have felt pain in a scale from 1 to 10. A physiotherapist monitors the participants' progress remotely.
Study NCT04160676 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Hydrocortisone, Ascorbic acid, Thiamine
Description: Combination of hydrocortisone, ascorbic acid, and thiamine
Study NCT04160676 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Normal saline
Description: Normal saline
Study NCT03970382 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: NeoTCR-P1 adoptive cell therapy
Description: The investigational agent in this protocol is NeoTCR P1, an autologous adoptive T cell therapy (ACT) for patients with solid cancer. NeoTCR P1 is composed of apheresis derived CD8 and CD4 T cells that are precision genome engineered to express one autologous TCR of native sequence that targets a neoepitope (neoE) presented by human leukocyte antigen (HLA) receptors exclusively on the surface of that patient's tumor cells and not on other cells in the body.
Study NCT03970382 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: nivolumab
Description: Nivolumab is a human IgG4 anti-PD-1 monoclonal antibody
Study NCT03970382 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: IL-2
Description: IL-2 is a biologic response modifier. It is a type of protein called a cytokine.
Study NCT04722081 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: physical therapy
Description: physical therapy-specific exercises
Study NCT03628222 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: ENB-TBLB
Description: ENB Guidance: The iLungTM SuperNavigator system will be used, it comprises of iLungTM ENB system, location catheter and guide catheter. The guide catheter can supply a 1.9 mm working channel for biopsy tools.~The location catheter is inserted into the guide catheter beforehand, then both are introduced via the working channel of the bronchoscope. Under guidance of ENB system, the location catheter reaches the lesion, and actual distance is confirmed by the X-ray.~TBLB: Location catheter is retracted, then the biopsy forceps and brush was introduced, and pathologic specimens are obtained.
Study NCT03628222 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: X-ray-TBLB
Description: Based on chest CT, the physician determines the lesion location. Under X-ray guidance, via the bronchoscope's working channel, the biopsy forceps and brush are introduced and pathologic specimens are obtained.
Study NCT04093973 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: bicycle stress echocardiography
Description: Study subjects will perform supine bicycle exercise with echocardiography performed before, during, and after exercise. Definity (perflutren microbubble contrast agent) will be used as needed to enhance echo images.
Study NCT02453100 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Mobility and pelvic floor exercise
Description: Mobility and pelvic floor exercises
Study NCT02453100 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Education
Description: Education on simple ways to manage incontinence
Study NCT02453100 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Education
Description: Education on simple ways to manage incontinence
Study NCT03163069 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: in-office bleaching with the conventional whitening dentifrice
Description: Participants will receive in-office tooth bleaching with 40% hydrogen peroxide (Opalescence Boost PF 40%) for the maxillary anterior teeth (2 sessions, with a 1-week interval). During the tooth bleaching procedure and 3 weeks after the procedure, the participants will be instructed to brush their teeth twice with the conventional whitening dentifrice.
Study NCT03163069 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: in-office bleaching with the whitening dentifrice containing blue covarine
Description: Participants will receive in-office tooth bleaching with 40% hydrogen peroxide (Opalescence Boost PF 40%) for the maxillary anterior teeth (2 sessions, with a 1-week interval). During the tooth bleaching procedure and 3 weeks after the procedure, the participants will be instructed to brush their teeth twice with the whitening dentifrice containing blue covarine.
Study NCT03163069 — intervention group
Intervention type: COMBINATION_PRODUCT
Group type: EXPERIMENTAL
Intervention: in-office bleaching with the regular dentifrice
Description: Participants will receive in-office tooth bleaching with 40% hydrogen peroxide (Opalescence Boost PF 40%) for the maxillary anterior teeth (2 sessions, with a 1-week interval). During the tooth bleaching procedure and 3 weeks after the procedure, the participants will be instructed to brush their teeth twice with the regular dentifrice.
Study NCT02786186 — intervention group
Intervention type: DRUG
Intervention: Secikinumab
Study NCT00694031 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Hemodialysis
Description: 3 times per week
Study NCT00694031 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: On-line hemodiafiltration
Description: 3 times per week
Study NCT04261322 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: x ray exposure
Description: exposure of whole body to x ray
Study NCT00755937 — intervention group
Intervention type: OTHER
Intervention: Data collection post infusion
Study NCT02595541 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: milrinone
Description: IV milrinone (0.75 mcg/kg) loading dose over one hour started during re-warming of the patient (before weaning from CPB) and followed by a maintenance dose of 0.75 mcg/kg/minutes till the end of the study.
Study NCT02595541 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Sildenafil
Description: IV milrinone (0.75 mcg/kg) loading dose over one hour started during re-warming of the patient (before weaning from CPB) and followed by a maintenance dose of 0.75 mcg/kg/minutes till the end of the study. After baseline measurements, sildenafil (1mg/kg) administered in ICU via a nasogastric tube, to be repeated every 4 hours via a nasogastric tube or orally. Sildnafil is presented in tablet form which was dissolved in water to make a concentration of 1 mg/ml.
Study NCT03547531 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Natural Tooth Brushing Method
Description: Natural tooth brushing method is the method that is naturally used by the people with horizontal, rotary, or simple up and down motions and any position of the brush without any instruction of particular tooth brushing method.
Study NCT03547531 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Modified Circular Tooth Brushing Method
Description: Modified Circular tooth brushing method is a combination of small circular motion of brushing with the position of the brush slightly reach underneath the gingival that are applied for each jaw in all facial surfaces and posterior lingual of tooth arches.
Study NCT02613416 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Denosumab
Description: monthly subcutaneous injections
Study NCT04717232 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blended learning approach to mentoring education for dental health care professionals
Description: The participants in the intervention group are dentists´ and dental hygienists´. The mentoring education for dental health care professionals (3 ECTS credits) will be organized by the program leader in Dentistry at the place-blinded. The aim of the mentoring education is to build understanding of how to support a student's professional development (both basic education and specialization) and transfer skills that are relevant to working as an independent expert in oral health care.
Study NCT04717232 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Blended learning approach to mentoring education for dental health care professionals
Description: The participants in the intervention group are dentists´ and dental hygienists´. The mentoring education for dental health care professionals (3 ECTS credits) will be organized by the program leader in Dentistry at the place-blinded. The aim of the mentoring education is to build understanding of how to support a student's professional development (both basic education and specialization) and transfer skills that are relevant to working as an independent expert in oral health care.
Study NCT04717232 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: The interprofessional online mentoring education
Description: The participants in the intervention group are dentists´ and dental hygienists´. The interprofessional online mentoring education (3 ECTS credits) will be organized in collaboration with the Finnish Dental Association in an online environment. The aim of the intervention is to in-crease mentors' competence in guidance processes and interactions, supporting students´ goal-oriented learning and professional evaluation, and providing constructive feedback.
Study NCT04717232 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: The interprofessional online mentoring education
Description: The participants in the intervention group are dentists´ and dental hygienists´. The interprofessional online mentoring education (3 ECTS credits) will be organized in collaboration with the Finnish Dental Association in an online environment. The aim of the intervention is to in-crease mentors' competence in guidance processes and interactions, supporting students´ goal-oriented learning and professional evaluation, and providing constructive feedback.
Study NCT02394600 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: one tablet daily for four months
Study NCT02545569 — intervention group
Intervention type: DEVICE
Group type: ACTIVE_COMPARATOR
Intervention: hearing aid (MD class IIa) - ITE, BTE, RIC
Description: Hearing aid means any wearable instrument or device designed for, offered for the purpose of, or represented as aiding persons with or compensating for, impaired hearing.
Study NCT02545569 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: hearing aid (MD class IIa) - ITE, BTE, RIC
Description: Hearing aid means any wearable instrument or device designed for, offered for the purpose of, or represented as aiding persons with or compensating for, impaired hearing.
Study NCT01662492 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Botulinum toxin type A Dose 1
Description: Botulinum toxin type A Dose 1 intramuscular injections into specified muscles.
Study NCT01662492 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: Botulinum toxin type A Dose 2
Description: Botulinum toxin type A Dose 2 intramuscular injections into specified muscles.
Study NCT01662492 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo (Normal Saline)
Description: Placebo (Normal Saline) intramuscular injections into specified muscles.
Study NCT02174640 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Coffee
Description: Coffee Beverage
Study NCT02174640 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: PLACEBO_COMPARATOR
Intervention: Water
Description: Water
Study NCT04407182 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Viusid and Asbrip
Description: Patients will be randomized to receive daily doses of 30 ml of Viusid and 10 ml of Asbrip every 8 hours plus standard care. Viusid and Asbrip will be administered orally.~Treatment duration: 21 days.
Study NCT02853877 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Weekly Incentive
Description: The tailored incentives intervention aims to assess the impact of tailored messaging and financial incentives on weight loss among obese employees.
Study NCT02050386 — intervention group
Intervention type: OTHER
Intervention: Cold pressor stimulation
Description: Immersion of the foot in 0-2 degrees C water for 50 seconds
Study NCT02050386 — intervention group
Intervention type: OTHER
Intervention: Sham Stimulation
Description: Immersion of the foot in room temperature water for 50 seconds
Study NCT01808417 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Near Infrared Imaging
Description: The intervention to be administered is the drug indocyanine green.
Study NCT00053027 — intervention group
Intervention type: BIOLOGICAL
Group type: EXPERIMENTAL
Intervention: rituximab
Study NCT00053027 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: cladribine
Study NCT03455647 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ASF promotion plus Girinka
Description: Behavior change communication promoting the consumption of milk produced in the household and other optimal maternal and child nutrition practices. The intervention will be implemented by government of Rwanda Community Health Workers.
Study NCT01979588 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: What's Going Around tool
Description: Provider has access to the What's Going Around tool
Study NCT01979588 — intervention group
Intervention type: OTHER
Group type: PLACEBO_COMPARATOR
Intervention: Control
Description: Provider does not have access to the What's Going Around tool but received information regarding the tool prior to study initiation
Study NCT04040959 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Nicotinamide riboside
Description: Nicotinamide riboside is a naturally occurring vitamin B3 derivative found in yeast, bacteria, and mammalian tissues, and also has been detected in cows' milk.
Study NCT04040959 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Nicotinamide riboside
Description: Nicotinamide riboside is a naturally occurring vitamin B3 derivative found in yeast, bacteria, and mammalian tissues, and also has been detected in cows' milk.
Study NCT01745263 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Omega 3 fatty acids
Description: Ratio EPA:DHA = 1:2~1 g/d
Study NCT01745263 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Strength Home Exercise
Study NCT00944008 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: DepoCyte
Study NCT02119182 — intervention group
Intervention type: BEHAVIORAL
Intervention: In-Person Outcome Assessment
Description: NIH Flexible Outcome Assessment Battery Framework Measures In-Person at 2 Weeks, 6 Months, and 12 Months, and by Phone at 3 Months.
Study NCT02119182 — intervention group
Intervention type: BEHAVIORAL
Intervention: Phone Outcome Assessment
Description: NIH Flexible Outcome Assessment Battery Framework Measures by Phone at 2 Weeks, 3 Months, 6 Months, and 12 Months.
Study NCT02119182 — intervention group
Intervention type: PROCEDURE
Intervention: 3T Magnetic Resonance Imaging (MRI)
Description: 3T Research MRI at 2 weeks and 6 months.
Study NCT02119182 — intervention group
Intervention type: PROCEDURE
Intervention: Blood Draw for Plasma, DNA, Serum, RNA
Description: Blood Draw for Plasma, DNA, Serum, RNA at baseline, in hospital (if applicable), 2 weeks, and 6 months (DNA at baseline only).
Study NCT02546037 — intervention group
Intervention type: DEVICE
Intervention: FX100 dialyzer
Description: comparison of dialyzers
Study NCT02546037 — intervention group
Intervention type: DEVICE
Intervention: SOLACEA 21H
Description: comparison of dialyzers
Study NCT03859570 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pentoxifylline
Description: Pentoxifylline (PTX) is a methylxanthine derivative that is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE). This enzyme, which has at least 5 subtypes, is responsible for inactivation of the important second messengers, Cyclic adenosine monophosphate (AMP) and cyclic guanosine monophosphate (GMP)
Study NCT03859570 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebos
Description: Placebo