AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04015986 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Microbiota Directed Complementary Food-2
Description: MDCF prototype with four complimentary food ingredients without powdered milk (rationale: lead with evidence from the recently completed pre-POC clinical trial of promoting growth promoting microbiota and positive effects on growth
Study NCT04015986 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: ACTIVE_COMPARATOR
Intervention: Ready to Use Supplementary Food
Description: Rice-lentil based RUSF (rationale: reference standard of care for post-SAM, MAM; based on knowledge of its effects on child growth and the gut microbiota)
Study NCT01619254 — intervention group
Intervention type: BEHAVIORAL
Group type: PLACEBO_COMPARATOR
Intervention: Hand washing with soap and hand finger nail clipping
Description: Assess the impact of hand washing with soap and nail clipping on child health
Study NCT01619254 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Hand washing with soap and hand finger nail clipping
Description: Assess the impact of hand washing with soap and nail clipping on child health
Study NCT03605329 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: to explore the severity of NAC in case of OSAS
Description: After overnight polysomnography, cardiovascular autonomic neuropathy will be evaluated by different methods: study of HRV, cardiovascular autonomic reflex test (Ewing), measurements of urinary levels of catecholamines and measurements of sweat gland dysfunction using Sudoscan.~The severity of CAN will be evaluated in T1D patients with moderate to severe OSAS (apnea hypopnea index (IAH) ≥15 / hour) compared to T1D patients with IAH \<15 / hour.
Study NCT03680014 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: CUSH
Description: Machine learning assisted remote monitoring/ telehealth platform to predict and prevent falls
Study NCT02929108 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Facebook
Description: Participants will be enrolled in a Secret Facebook group for social support and education
Study NCT02929108 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: ACCESS
Description: Intervention will have two components.~1. Participants will be enrolled in a Secret Facebook group for social support and education~2. Participants will use web conferencing technology to participate in their interdisciplinary team meeting
Study NCT03742713 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: CPC634 (CriPec® docetaxel)
Description: Docetaxel containing CriPec® nanoparticles
Study NCT01394809 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: motor cognitive therapies
Description: pre-test; 6 weeks intervention: week 1-3: 5 times per week 60 minutes a day. Week 4-6: 3 times per week 60 minutes a day; post-test; follow-up)
Study NCT01394809 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: motor cognitive therapies
Description: pre-test; 6 weeks intervention: week 1-3: 5 times per week 60 minutes a day. Week 4-6: 3 times per week 60 minutes a day; post-test; follow-up)
Study NCT06076343 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: DBT skills-training and Family Connections interventions
Description: DBT skills-training program includes four modules: 1. Mindufulness, 2. Distress Tolerance, 3. Emotion Regulation, 4. Interpersonal effectiveness.~FC program includes six modules: 1. Introduction, 2. Family Education, 3. Relationship Mindfulness Skills, 4. Family Environment Skills, 5. Validation Skills, 6. Problem Management Skills.
Study NCT00742573 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antidepressants through Texas Medication Algorithm (TMA)
Description: Treatment with medication will follow the TMA for depression. Antidepressant medications may include any of the following: citalopram, escitalopram, paroxetine, sertraline, venlafaxine XR, bupropion SR, duloxetine, nortriptyline, and mirtazapine.
Study NCT00742573 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Antidepressants through Texas Medication Algorithm (TMA)
Description: Treatment with medication will follow the TMA for depression. Antidepressant medications may include any of the following: citalopram, escitalopram, paroxetine, sertraline, venlafaxine XR, bupropion SR, duloxetine, nortriptyline, and mirtazapine.
Study NCT00742573 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Brief Interpersonal Psychotherapy (IPT-B)
Description: IPT-B consists of twelve 50-minute sessions, divided into three phases, focusing on an interpersonal problem or problems.
Study NCT03681730 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Virtual Reality
Description: Participants wear a Virtual Reality headset that consists of a ASUS phone and a VOX+ Z3 3D Virtual Reality Headset. The phone runs the VR Roller Coaster app to produce the virtual environment.
Study NCT03378479 — intervention group
Intervention type: DRUG
Group type: OTHER
Intervention: SOC +Posaconazole 18 MG/ML (milligram/milliliter)
Description: .2\*300mg/d IV on day 1, followed by 1\*300mg/d IV from day 2 for 7 days (total 7 days)
Study NCT03378479 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: standard of care (SOC)
Description: treatment for influenza pneumonia at the investigators discretion
Study NCT00609349 — intervention group
Intervention type: DEVICE
Group type: OTHER
Intervention: ETED, CPET, RHC
Description: exercise tricuspid echo doppler (ETED): allows the estimation of systolic pulmonary arterial pressure at exercise cardiopulmonary exercise test (CPET) allows to measures exercise capacity (peakVO2)~right heart catheterisation (RHC): is the gold standard for the measurement of pulmonary arterial pressure values
Study NCT02998320 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Genvoya
Description: Oral use (one tablet each day); 150/150/200/10 mg; 28 days
Study NCT02860091 — intervention group
Intervention type: DRUG
Intervention: Ropivacaine infusion
Description: Delivered via paravertebral nerve block catheter.
Study NCT03298087 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: radical prostatectomy
Description: surgical removal of the prostate
Study NCT03298087 — intervention group
Intervention type: RADIATION
Group type: EXPERIMENTAL
Intervention: stereotactic body radiotherapy
Description: Highly targeted radiation
Study NCT03968367 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Magnetic activated sperm sorting
Description: MACS is a technique which allows the spermatozoa with the best characteristics to be selected for use in assisted reproduction treatments. This technique removes apoptotic spermatozoa - those which will die without achieving fertilisation - and selects the healthy ones, thus increasing the possibility of pregnancy.
Study NCT02545296 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: In-vitro Diagnostics
Description: Ex-vivo performed diagnostic blood based test.
Study NCT01737255 — intervention group
Intervention type: OTHER
Intervention: Psychological questionnaires
Description: All recruits will complete questionnaires at 6 time points to assess psychological impact
Study NCT02179593 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 2-Segment SARPE
Description: Le Fort I osteotomy with oppening of the median palatal suture and SARPE.
Study NCT02179593 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: 3-Segment SARPE
Description: Le Fort I osteotomy with two parallel osteotomies symetrically positioned with reference to the median palatal suture and SARPE.
Study NCT01830153 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: RAD001
Study NCT03495427 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: F-DCFPyL Injection
Description: F-DCFPyL Injection is a radioactive diagnostic imaging agent indicated for imaging of patients with recurrent prostate cancer.
Study NCT03495427 — intervention group
Intervention type: DIAGNOSTIC_TEST
Group type: EXPERIMENTAL
Intervention: PSMA PET
Description: PSMA PET imaging (for men with high GC >0.45) will be done after 2 years post-treatment, then yearly up to 5 years.
Study NCT04027465 — intervention group
Intervention type: DIETARY_SUPPLEMENT
Group type: EXPERIMENTAL
Intervention: Egg allergy oral desensitization
Description: Subjects in the treatment will begin treatment by undergoing an egg oral challenge. This will confirm that the subject is still allergic to egg and establish the dose of egg the subject can tolerate. The last dose of egg tolerated during the challenge will serve as the first desensitization dose Subjects will then come to the research center every two weeks to receive their dose increases until they reach the maintenance dose of 300 mg. Subjects will then enter the maintenance phase for one year. During this period they will undergo another oral food challenge one month after attaining the maintenance dose
Study NCT04636450 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Rotatory technique pulpectomy
Description: Primary mandibular molars treated with a rotatory technique pulpectomy and a K3 system or a Kedo-S system.
Study NCT04636450 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Rotatory technique pulpectomy
Description: Primary mandibular molars treated with a rotatory technique pulpectomy and a K3 system or a Kedo-S system.
Study NCT03298087 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Leuprolide
Description: Lowers serum testosterone
Study NCT03298087 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: apalutamide
Description: antiandrogen
Study NCT03298087 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: abiraterone
Description: Inhibits androgen synthesis
Study NCT04636450 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: Manual pulpectomy
Description: Primary mandibular molars treated with a manual pulpectomy and a K-file system or a Kedo-SH system.
Study NCT04636450 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Manual pulpectomy
Description: Primary mandibular molars treated with a manual pulpectomy and a K-file system or a Kedo-SH system.
Study NCT05222360 — intervention group
Intervention type: OTHER
Intervention: Education
Description: 3 educational sessions about body image and nutrition
Study NCT04931160 — intervention group
Intervention type: OTHER
Group type: OTHER
Intervention: Blood, fluid, sells and urine samples
Description: Blood, fluid, sells and urine samples will be collected.
Study NCT04931160 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Blood, fluid, sells and urine samples
Description: Blood, fluid, sells and urine samples will be collected.
Study NCT04556734 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etrasimod
Description: Etrasimod 2 mg tablet by mouth, once daily
Study NCT04556734 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Etrasimod
Description: Etrasimod 3 mg (1 mg and 2 mg tablets) by mouth, once daily
Study NCT04556734 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Placebo
Description: Etrasimod matching placebo tablet by mouth, once daily
Study NCT02335372 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wide-Field White Light Imaging
Description: Initial wide-field white light images acquired of cervix in unpolarized and cross-polarized modes during cervical colposcopy.
Study NCT02335372 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Acetic Acid
Description: 3-6% acetic acid applied to cervix after wide-field while light imaging during colposcopy.
Study NCT02335372 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Proflavine Solution
Description: Topical application of 0.01% proflavine solution applied for 1 minute to cervix after sites for biopsy have been identified during colposcopy.
Study NCT03070834 — intervention group
Intervention type: DEVICE
Group type: EXPERIMENTAL
Intervention: Cook 'Celect' retrievable inferior vena cava filter
Description: Cook 'Celect' device will be deployed If randomized to rIVCF insertion
Study NCT03842280 — intervention group
Intervention type: DEVICE
Intervention: Diaphragm ultrasound assessment & Esophageal pressure measurement
Description: Diaphragm ultrasound assessment and/or Esophageal pressure measurement before, during and after spontaneous breathing trial
Study NCT02220400 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Ketamine
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phentermine-Topiramate
Description: Extended Release at dose of 7.5/46 mg oral daily
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Phentermine-Topiramate
Description: Extended Release at dose of 7.5/46 mg oral daily
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Liraglutide
Description: dose of 3 mg subcutaneous daily
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Liraglutide
Description: dose of 3 mg subcutaneous daily
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Naltrexone/bupropion
Description: Oral naltrexone extended-release/bupropion extended-release at dose of 32/360 mg oral daily (divided in 2 tables in morning and 2 tablets in evening)
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Naltrexone/bupropion
Description: Oral naltrexone extended-release/bupropion extended-release at dose of 32/360 mg oral daily (divided in 2 tables in morning and 2 tablets in evening)
Study NCT03374956 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Phentermine
Description: 15-37.5 mg oral daily
Study NCT00752219 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ceftazidime/NXL104 + metronidazole
Description: IV TID
Study NCT00752219 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: meropenem
Description: IV TID
Study NCT03847519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: ADXS-503
Description: A live attenuated Listeria monocytogenes (Lm)-based immunotherapy bioengineered to elicit T cell responses against shared tumor antigens commonly found in patients with squamous and non-squamous NSCLC.
Study NCT03847519 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pembrolizumab
Description: a programmed death receptor-1 (PD-1)- blocking antibody.
Study NCT01242085 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: trumatch group
Description: these patient will have CT based customized knee instruments used for surgery
Study NCT01242085 — intervention group
Intervention type: PROCEDURE
Group type: ACTIVE_COMPARATOR
Intervention: control group
Description: these patients will have standard instrumentation used for for knee replacement
Study NCT04056221 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Acupuncture
Description: Acupuncture stimulation was done manually, using single-use acupuncture needles that will be inserted on the selected acupoints (R6, E6, E2, Ig4, VC24, TA23, B2) once a week,for 8 weeks, 20 minutes sessions with 12 weeks of follow up.
Study NCT04056221 — intervention group
Intervention type: OTHER
Group type: SHAM_COMPARATOR
Intervention: Sham acupuncture
Description: The sham acupuncture consists of needles that achieves no skin penetration and are holden on the points by an adhesive pad.
Study NCT02096289 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Thioridazine
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Rocaltrol
Description: tablet, Vitamin 1-OH-D3, total 1.25-2.5 mg daily
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Vitamin D
Description: tablets, vitamin D3, 30 microgram daily
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Vitamin D
Description: tablets, vitamin D3, 30 microgram daily
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Calcium
Description: tablets, 400 mg calcium, 3 times daily
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: PLACEBO_COMPARATOR
Intervention: Calcium
Description: tablets, 400 mg calcium, 3 times daily
Study NCT00990678 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Calcium
Description: tablets, 400 mg calcium, 3 times daily
Study NCT02637271 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Low calorie total meal replacement
Description: Participants will be provided instruction in the appropriate use of the meal replacement product. The participants will be directed to refrain from all items of food for a period of 21 days except for the meal replacement products and vitamin supplements provided by the investigators (1120 kcal/day). Optifast™ 800 total meal replacement shakes will be provided to the participants for the 21 day intervention period.
Study NCT02637271 — intervention group
Intervention type: OTHER
Group type: ACTIVE_COMPARATOR
Intervention: Low calorie typical diet
Description: Participants will be directed to use portion control to maintain a calorie level no greater than 1120 kcal per day. The participants will be directed to continue to consume food and beverage items that are representative of their typical diet (with the exception of reduced portions). Participants will be provided resources to assist them in determining caloric content of foods eaten.
Study NCT02973919 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Eye Movement Desensitization and Reprocessing Therapy
Description: In 1989, Shapiro discovered that while talking about negative life events or thoughts, rhythmic eye movements on a horizontal axis can alleviate the associated vividness and burden (Shapiro, 1989). She established the psychodynamic-behavioral Eye Movement Desensitization and Reprocessing (EMDR) Therapy, which includes the induction of rhythmic eye movements as a central feature. EMDR is regarded as an efficient treatment tool. Several times it has also been successfully applied in the field of specific phobias (de Jongh, ten Broeke, \& Renssen, 1999; de Jongh, Holmshaw, Carswell, \& van Wijk, 2011; Lapsekili \& Yelboga, 2014; Muris, Merckelbach, van Haaften, \& Mayer, 1997) and there is a standard protocol for using EMDR on specific fears and phobias (de Jongh, 2015).
Study NCT02973919 — intervention group
Intervention type: BEHAVIORAL
Group type: ACTIVE_COMPARATOR
Intervention: Virtual Reality Exposure Therapy
Description: Exposure to fear-evoking stimuli is conducted more often in virtual environments using simulators or similar computer-technologies (Virtual Reality Exposure Therapy, VRET). One great advantage of using VR-technologies is that it is possible to create an environment which is highly controllable by its creators. Feared stimuli or scenarios can be varied on individual purposes and presented several times. This facili- tates the practice of exposure-based treatments especially for situations or places diffi- cult to access or requiring a considerable amount of time and/or money (e.g. being in war zones or a passenger on a flight), where in vivo exposures have often not been con- ducted or only in a limited manner (Mühlberger \& Pauli, 2011).
Study NCT02973919 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Virtual Reality Exposure Therapy
Description: Exposure to fear-evoking stimuli is conducted more often in virtual environments using simulators or similar computer-technologies (Virtual Reality Exposure Therapy, VRET). One great advantage of using VR-technologies is that it is possible to create an environment which is highly controllable by its creators. Feared stimuli or scenarios can be varied on individual purposes and presented several times. This facili- tates the practice of exposure-based treatments especially for situations or places diffi- cult to access or requiring a considerable amount of time and/or money (e.g. being in war zones or a passenger on a flight), where in vivo exposures have often not been con- ducted or only in a limited manner (Mühlberger \& Pauli, 2011).
Study NCT02335372 — intervention group
Intervention type: PROCEDURE
Group type: EXPERIMENTAL
Intervention: Wide-Field Fluorescence Imaging
Description: Wide-field imaging in fluorescence mode performed during cervical colposcopy after topical proflavine solution applied.
Study NCT00623922 — intervention group
Intervention type: BEHAVIORAL
Group type: EXPERIMENTAL
Intervention: Patient education with individual nurse consultations
Description: 3 group meetings followed by 1-2 individual nurse consultations.
Study NCT00232011 — intervention group
Intervention type: DRUG
Group type: EXPERIMENTAL
Intervention: Pimecrolimus Cream 1%
Description: Pimecrolimus cream 1 %
Study NCT00679276 — intervention group
Intervention type: PROCEDURE
Intervention: Prolift
Description: surgical repair of vaginal prolapse
Study NCT04954430 — intervention group
Intervention type: DIAGNOSTIC_TEST
Intervention: pupillometer
Description: The dynamic changes of PLR were measured using the PLR-3000 pupillometer (NeurOptics, CA, USA), a hand-held portable device. Determination of PLR with automated pupillometry can be performed with a rubber cup covering the measured eye and the subject's hand covering the non-measured eye. A flash of visible white light with a duration of 0.8 sec and a pulse intensity of 50 µW is delivered to induce a pupillary reflex, and repeated video images at more than 30 frames/sec are stored for 6.65 sec. The device provided the examiner with maximum and minimum pupil size (Init and End), constriction percentage (%PLR), latency (LAT), constriction and dilation velocity (CV and DV), and T75.
Study NCT02205931 — intervention group
Intervention type: OTHER
Group type: EXPERIMENTAL
Intervention: Ketogenic diet
Description: The ketogenic diet is a high fat diet designed to mimic the effects on the body of starvation. The premise is the main energy intake is fat, which is utilised in the body and produces ketones.
Study NCT02205931 — intervention group
Intervention type: DRUG
Group type: ACTIVE_COMPARATOR
Intervention: Antiepileptic drug therapy
Description: The control intervention will be drug therapy with the most appropriate further antiepileptic drug for a particular child, depending on their presenting seizures and syndrome and previous drugs used, and chosen by the expert clinician responsible for management of the patient's epilepsy.