AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT05583201 — Biomarker: CLDN18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN18; UNQ778/PRO1572
Study NCT05583201 — Biomarker: KLRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRK1; D12S2489E; NKG2D
Study NCT05451784 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06546566 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT06147570 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05555251 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05555251 — Biomarker: FCGR2B
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study NCT05007834 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT04908176 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study NCT05145335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06500676 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT04727151 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04727151 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06736119 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study NCT05484570 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT05264025 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05930340 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04703478 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04624880 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study NCT05109169 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT06322056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06549556 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05043090 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT05043090 — Biomarker: PRCC mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCC; TPRC
Study NCT05043090 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study NCT06096909 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT05315700 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05315700 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04590664 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04830137 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT04773951 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study NCT06273644 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study NCT01261026 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT01261026 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT02577094 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT06272422 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06288945 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study NCT05845905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05184998 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT05549778 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study NCT05785585 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT06491082 — Biomarker: NOX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOX4; RENOX
Study NCT06491082 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT04936841 — Biomarker: NKTR mRNA
Type: Predictive Biomarker (PRD)
Genes: NKTR
Study NCT04936841 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04813926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06032026 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT04494334 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study NCT00002037 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT05667584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04743453 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05146284 — Biomarker: AMN mRNA
Type: Predictive Biomarker (PRD)
Genes: AMN; UNQ513/PRO1028
Study NCT05146284 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study NCT06618859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06735508 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study NCT06735820 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study NCT06734182 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06735599 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06736054 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04836832 — Biomarker: PI3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PI3; WAP3; WFDC14
Study NCT04836832 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT05880758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03025360 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT03025360 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study NCT03025360 — Biomarker: NTRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK3; TRKC
Study NCT05999396 — Biomarker: CD276 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05449821 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06503432 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05465161 — Biomarker: STING1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT05111561 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study NCT05111561 — Biomarker: MAP2K2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT05111561 — Biomarker: RAS pathway
Type: Safety Biomarker (SAF)
Study NCT05178550 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study NCT05178550 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT05178550 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT06682520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05264974 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04921241 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04921241 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04921241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04868604 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05104567 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT05104567 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05104567 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06732492 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study NCT06528691 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT06528691 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT06018337 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06018337 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06018337 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06018337 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05897541 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05309668 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study NCT05109364 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT04962191 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04930445 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05290922 — Biomarker: CDO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDO1
Study NCT05290922 — Biomarker: CELF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CELF4; BRUNOL4
Study NCT06428487 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT04979052 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT05101096 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05101096 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05101096 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05101096 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT05944016 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT06578078 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT06668272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06495333 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study NCT05640830 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06356922 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study NCT06356922 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT06590779 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study NCT06592092 — Biomarker: CD276 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05086627 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT06593145 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06472583 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06472583 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05248256 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT05393791 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study NCT06615206 — Biomarker: MECP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MECP2
Study NCT06483048 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT05069129 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT01852682 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05527301 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study NCT06706414 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT06155604 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05204329 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT05241873 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05031988 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06095505 — Biomarker: BBC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BBC3; PUMA
Study NCT06718452 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT06734273 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05103943 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT06491433 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06472518 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study NCT06178419 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06490380 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study NCT05679570 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05542524 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study NCT06397001 — Biomarker: SAA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAA1
Study NCT06550011 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT06011395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04912648 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT05605496 — Biomarker: Netrin-1
Type: Safety Biomarker (SAF)
Genes: NTN1; NTN1L
Study NCT04970134 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04970134 — Biomarker: SH3PXD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT05961358 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06480513 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04759274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05384119 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study NCT05384119 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05384119 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05384119 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04866628 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05228470 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT05200104 — Biomarker: AMN mRNA
Type: Predictive Biomarker (PRD)
Genes: AMN; UNQ513/PRO1028
Study NCT05200104 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study NCT06341166 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study NCT06261034 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04752293 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04752293 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04752293 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT04679233 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05940610 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT05442749 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05007652 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT05987566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05799287 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05131204 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT05131204 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05380284 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05874323 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study NCT05874323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04746118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06474104 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT06564961 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study NCT05338099 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study NCT06220721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06620029 — Biomarker: BMX mRNA
Type: Predictive Biomarker (PRD)
Genes: BMX
Study NCT06620029 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT05906953 — Biomarker: RPE65 mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE65
Study NCT05224960 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT06138964 — Biomarker: SPARC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPARC; ON
Study NCT06138964 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study NCT06561620 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02860559 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study NCT05159778 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05159778 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT05173259 — Biomarker: Salivary secretion
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06114615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05189613 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT04501159 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05834309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06467617 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT05604040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06453044 — Biomarker: CD79B mRNA
Type: Predictive Biomarker (PRD)
Genes: CD79B; B29; IGB
Study NCT06333314 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study NCT06223750 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT06049082 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT05603884 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT04886401 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05805566 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06644469 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT06704620 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06116149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06586658 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05080946 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study NCT05080946 — Biomarker: PTGS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGS1; COX1
Study NCT05080946 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study NCT04715191 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study NCT04715191 — Biomarker: IL15 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL15
Study NCT04715191 — Biomarker: IL21 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL21
Study NCT06734533 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT06734533 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06734533 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT06734533 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT06736080 — Biomarker: UNC13D mRNA
Type: Predictive Biomarker (PRD)
Genes: UNC13D
Study NCT06736080 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT06444217 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT06235801 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT06525675 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06525675 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06228924 — Biomarker: PKP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PKP2
Study NCT05259150 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05244707 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05244707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05244707 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04557865 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study NCT04557865 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04557865 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT04557865 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study NCT04557865 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study NCT04557865 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE