AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34726293 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 34726293 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34726293 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 34726293 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 35115003 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35115003 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35115003 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35115003 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 32305012 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 32305012 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34126291 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33657443 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36256926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34429137 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 33079971 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 34493311 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32506857 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33716034 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 33716034 — Biomarker: NFKB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKB2; LYT10
Study 33079935 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33079935 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33079935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36424116 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 34097854 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 34154896 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34518101 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34518101 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 36225301 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 32250418 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 32250418 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35162622 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34898916 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33870762 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 33870762 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 33609624 — Biomarker: BORA mRNA
Type: Predictive Biomarker (PRD)
Genes: BORA; C13orf34
Study 32488909 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32488909 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32488909 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34224858 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 34224858 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 34224858 — Biomarker: miR-155
Type: Safety Biomarker (SAF)
Genes: MIR155
Study 35352014 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33589759 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35276789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35961692 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34613339 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36188617 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 32778175 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32778175 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33040778 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33040778 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 33040778 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35217236 — Biomarker: GDF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: GDF9
Study 35217236 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 33091433 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34419285 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34476847 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 32469138 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 34324231 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34324231 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33352723 — Biomarker: CHEK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK1; CHK1
Study 33352723 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 33352723 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 35525132 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32859608 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34324138 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 32847923 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 35560407 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33836990 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33836990 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36124638 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 32835687 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 34920291 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 36396522 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 36240638 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 36240638 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 36240638 — Biomarker: CA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA2
Study 36240638 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 36240638 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32369546 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33663739 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34156097 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33548002 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 32143061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32794131 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32794131 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 32794131 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32579403 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 35598597 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 35598597 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32390731 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33082202 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 33486990 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 33486990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32868661 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32868661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35390727 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 32211907 — Biomarker: GAL3ST1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAL3ST1; CST
Study 35488808 — Biomarker: MFF mRNA
Type: Predictive Biomarker (PRD)
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 36442482 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 36442482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34031547 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34031547 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35912517 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 35912517 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33794080 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33794080 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35065931 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33982949 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2
Study 33688713 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 33688713 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 35349835 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33431358 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 34423361 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34325134 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34325134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34325134 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 32990607 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35448942 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 35448942 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33169175 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32685258 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33827781 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 33152119 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 33152119 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35422208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33638248 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32594135 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 34320250 — Biomarker: FAIM mRNA
Type: Predictive Biomarker (PRD)
Genes: FAIM; FAIM1
Study 33374465 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 33374465 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 33098992 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 33098992 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 33098992 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 32151211 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35608106 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 33070288 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 36271804 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 36271804 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 36271804 — Biomarker: CCL24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL24; MPIF2; SCYA24
Study 33903925 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34302514 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 34302514 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 34724045 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32507136 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 33307546 — Biomarker: OAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAS1; OIAS
Study 33307546 — Biomarker: OAS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAS2
Study 33307546 — Biomarker: OAS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: OAS3; P/OKcl.4
Study 33307546 — Biomarker: TYK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYK2
Study 33307546 — Biomarker: DPP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPP9; DPRP2
Study 33307546 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 36175722 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 32498637 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32498637 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 34186201 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33742652 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35834624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35451096 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32039840 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 34329947 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34263416 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34615782 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 34496751 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 35233984 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 35373021 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 33715648 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study 33715648 — Biomarker: MAP3K10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K10; MLK2; MST
Study 32985369 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 32985369 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 35060544 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 34000245 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 34000245 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 34000245 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 34475187 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33567888 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33567888 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36085679 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 34547013 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 36274214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36274214 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36274214 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35584872 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 35584872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34271175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34271175 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33016688 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34184784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34010180 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33259846 — Biomarker: PON2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON2
Study 33259846 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 33303575 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 33303575 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36168844 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36168844 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36168844 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32880602 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32880602 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32880602 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32880602 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 32880602 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33510373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33610736 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 34182194 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 34182194 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33972573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32776907 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 35410182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36268614 — Biomarker: HINT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 33980184 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35184297 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 35184297 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 34649747 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36302893 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33955714 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33955714 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33506388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32248825 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 32248825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34969619 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34077684 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 34077684 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 34077684 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 33574564 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 33574564 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 32664290 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32664290 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 32072763 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 32072763 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34961782 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 33203880 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 34414672 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 34414672 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33730928 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33730928 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34080044 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 34080044 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34599865 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34599865 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 34521417 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33183463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33183463 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32726514 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1