AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35446936 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 33462752 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 33462752 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 32460816 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32460816 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 32450154 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32256955 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 32209396 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 32209396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32209396 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 32209396 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 32209396 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33793979 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33793979 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32869451 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 33596357 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33596357 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34053111 — Biomarker: ID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ID1; BHLHB24; ID
Study 34053111 — Biomarker: NID1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NID1; NID
Study 34053111 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34053111 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 34053111 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34144995 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33002071 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35247908 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35247908 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32216011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32216011 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35222898 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 35222898 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 35222898 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 35818134 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 34800399 — Biomarker: Lysosomal alpha-glucosidase
Type: Safety Biomarker (SAF)
Genes: GAA
Study 34800399 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34800399 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 34087752 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 33741218 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32048900 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 32048900 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34716791 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34716791 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32660609 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32660609 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32660609 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36477733 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 36477733 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32095884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32696396 — Biomarker: DHODH mRNA
Type: Predictive Biomarker (PRD)
Genes: DHODH
Study 32696396 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33741010 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 35699175 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 32495059 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32495059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32495059 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34809581 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34466041 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 34021585 — Biomarker: MMD mRNA
Type: Predictive Biomarker (PRD)
Genes: MMD; PAQR11
Study 34844978 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34844978 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34844978 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34844978 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 35554859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36397173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35704124 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34040607 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32927677 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32202124 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 34529156 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32393980 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 32393980 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 34228592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32783769 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34024173 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 34879822 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33010188 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 34284381 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32453116 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 35002817 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32573426 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36349701 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 36349701 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33768310 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 36455187 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 32168870 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 33332778 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33759644 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32646941 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32646941 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 36128889 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36128889 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33266022 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 33266022 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 33266022 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36228567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34732114 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34814584 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33441158 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34015241 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32160058 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35051263 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 35051263 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 32207354 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32207354 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34126053 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32236602 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 33634831 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34849536 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32359376 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32359376 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33160266 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 35443789 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34535522 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34535522 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35101183 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34607344 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 32771002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35416502 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 32959502 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32413284 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 32413284 — Biomarker: SARM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARM1; KIAA0524; SAMD2; SARM
Study 32413284 — Biomarker: SNX32 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNX32; SNX6B
Study 32413284 — Biomarker: CTSH mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSH; CPSB
Study 32413284 — Biomarker: Netrin-1
Type: Safety Biomarker (SAF)
Genes: NTN1; NTN1L
Study 36261812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35986421 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35986421 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35986421 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32498088 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 32279529 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32599106 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 33953123 — Biomarker: OPRD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: OPRD1; OPRD
Study 32233959 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 35037278 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 36306283 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 34029555 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 34309427 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 34098827 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34098827 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34098827 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 34098827 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35254665 — Biomarker: MVP mRNA
Type: Predictive Biomarker (PRD)
Genes: MVP; LRP
Study 34425776 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 33310698 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33493393 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33086239 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32780946 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 35977807 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34338136 — Biomarker: miR-216b
Type: Safety Biomarker (SAF)
Genes: MIR216B
Study 33378478 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 35165387 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35165387 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 35165387 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 32907904 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35631137 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35631137 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33739852 — Biomarker: ETV6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV6; TEL; TEL1
Study 33739852 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 32921069 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33253933 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32602362 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 35234092 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33399273 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 32452344 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 32452344 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32299093 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 32299093 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 32299093 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 35235653 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 35235653 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35084948 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35084948 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 34398667 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 32166899 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 32166899 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 32166899 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 32166899 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34407667 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34351608 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34353696 — Biomarker: Interleukin 6 receptor alpha
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: IL6R
Study 34353696 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36265753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36265753 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32857933 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 32857933 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 32857933 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 36147166 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34340595 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36371180 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 34684393 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34684393 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34684393 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35344737 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 35344737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32696178 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32696178 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32696178 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34554368 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 34380150 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34380150 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 32994187 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32544011 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32544011 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32544011 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32544011 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 33455201 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 32641320 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34921121 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 32877576 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36099876 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 36099876 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36331328 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 36331328 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36331328 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 36331328 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 36331328 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 36331328 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 34006921 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34006921 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 34006921 — Biomarker: CSF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1
Study 34006921 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36206152 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 35176724 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 33150385 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36394384 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34628740 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34628740 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34159451 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 32928387 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 32001832 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32001832 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32001832 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105