AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34404427 — Biomarker: PAG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAG1; CBP; PAG
Study 34404427 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 36117055 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 33023684 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33299898 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32324435 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 32324435 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32324435 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34971795 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 34971795 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 32304015 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 32304015 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 35817957 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 32333541 — Biomarker: ST7 mRNA
Type: Predictive Biomarker (PRD)
Genes: ST7; FAM4A1; HELG; RAY1
Study 32333541 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34883037 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 32912276 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33164956 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 33164956 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 37286262 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 32541548 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32541548 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35749144 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32332617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35773633 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 35773633 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35773633 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 35773633 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33764445 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33768619 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35798534 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study 36041126 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 34335840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34385543 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32684486 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34061883 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 33538417 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 32074419 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33979838 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34051124 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33751636 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 34230150 — Biomarker: ITFG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITFG1; LNKN-1; TIP; CDA08
Study 33694196 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 35770629 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35770629 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32450869 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 36143879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33080005 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32847020 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33841399 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33526633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35493500 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34259423 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 35304048 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34086101 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32548624 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 34526250 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33590901 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32315461 — Biomarker: DBI mRNA
Type: Predictive Biomarker (PRD)
Genes: DBI
Study 32844557 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34287900 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 34125503 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34125503 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 34630155 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 34247582 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 33974170 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33974170 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35095084 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 36283254 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 34542654 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32034016 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 32138790 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32138790 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32957816 — Biomarker: HEATR5A mRNA
Type: Predictive Biomarker (PRD)
Genes: HEATR5A; C14orf125; KIAA1316
Study 32957816 — Biomarker: PRRC2B mRNA
Type: Predictive Biomarker (PRD)
Genes: PRRC2B; BAT2L; BAT2L1; KIAA0515
Study 32957816 — Biomarker: RBM25 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBM25; RNPC7
Study 32957816 — Biomarker: ZC3H13 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZC3H13; KIAA0853
Study 32957816 — Biomarker: LRRK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRRK1; KIAA1790
Study 32741773 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 33711262 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32129141 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33832352 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35511258 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35272940 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 35241246 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34648948 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33727409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32851636 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 35037057 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 33164259 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35397122 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 36419389 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 36419389 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 34052121 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34151818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32106141 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 34027030 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32402681 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 34118609 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35235659 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 35835685 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 34693933 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33966435 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 33966435 — Biomarker: PDGFRB mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRB; PDGFR; PDGFR1
Study 32330183 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32744441 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32744441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33280953 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35954922 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35954922 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 32145111 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 32145111 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 32145111 — Biomarker: CD81 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD81; TAPA1; TSPAN28
Study 33913511 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33913217 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35596774 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32744373 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32553151 — Biomarker: DGAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 33211592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34914868 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33295137 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33258566 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 33769666 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 33769666 — Biomarker: SCN8A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN8A; MED
Study 32975159 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35405482 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35405482 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 33278235 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35691791 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 35691791 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 34003364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34003364 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35670063 — Biomarker: DRD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DRD2
Study 35670063 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 36184545 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36184545 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 32148083 — Biomarker: SH2B3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SH2B3; LNK
Study 32148083 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32148083 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34554643 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32286392 — Biomarker: ANGPTL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL5; UNQ5795/PRO19600
Study 32286392 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32286392 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34601410 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 34601410 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 34966064 — Biomarker: PTPRF mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRF; LAR
Study 34966064 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 33766805 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33179154 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32359741 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 32359741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34871182 — Biomarker: TNFSF14 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 32722015 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32722015 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34514770 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 35644166 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 34733346 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33720873 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 35478978 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 35478978 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 35552172 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32558052 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32003938 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32003938 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33357247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35896083 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 33253354 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 35834528 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34608929 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 34004483 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 34004483 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 34004483 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34455435 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34455435 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32931919 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32147182 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36131603 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 36131603 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 35725494 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34652968 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 32634774 — Biomarker: OCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: OCA2; D15S12; P
Study 34227954 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34606387 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 32747497 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32747497 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 33203707 — Biomarker: SLC23A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC23A1; SVCT1; YSPL3
Study 33203707 — Biomarker: SLC23A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC23A3; E2BP3; SVCT3
Study 33203707 — Biomarker: CHPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHPT1; CPT1; MSTP022
Study 33203707 — Biomarker: BCAS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCAS3
Study 33203707 — Biomarker: SNRPF mRNA
Type: Predictive Biomarker (PRD)
Genes: SNRPF; PBSCF
Study 33203707 — Biomarker: RER1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RER1
Study 33203707 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 33203707 — Biomarker: RGS14 mRNA
Type: Predictive Biomarker (PRD)
Genes: RGS14
Study 33203707 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 33203707 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 33992032 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33992032 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 33992032 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 33992032 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33883079 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33883079 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35553356 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33957242 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 33957242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32057567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32057567 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33653757 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 32196623 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 33756239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34275830 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34275830 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34275830 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 33196606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33196606 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32815921 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35690783 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 616120383 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33092618 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 36028843 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 36028843 — Biomarker: ADH1B mRNA
Type: Predictive Biomarker (PRD)
Genes: ADH1B; ADH2
Study 33803814 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34559129 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35413644 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33155868 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32467417 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32467417 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32467417 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 32740347 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 36442902 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33620419 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 33620419 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)