AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04935255 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT04923243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04923243 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study NCT04767698 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06611839 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study NCT06611839 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study NCT06676215 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study NCT06676124 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study NCT06178367 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04735315 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06512610 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study NCT06315777 — Biomarker: GREM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GREM1; CKTSF1B1; DAND2; DRM; PIG2
Study NCT06315777 — Biomarker: HAS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HAS2
Study NCT06315777 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study NCT06307249 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT06307249 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT06307249 — Biomarker: VEGF
Type: Predictive Biomarker (PRD)
Genes: VEGFA; VEGF-A; VPF
Study NCT06307249 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT05686434 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04369495 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06440603 — Biomarker: KLF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF1; EKLF
Study NCT05842486 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study NCT04780529 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study NCT04780529 — Biomarker: GUCY2C mRNA
Type: Predictive Biomarker (PRD)
Genes: GUCY2C; GUC2C; STAR
Study NCT05303415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05988918 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study NCT04303975 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05312606 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05312606 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT06709872 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT06709872 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study NCT06715098 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study NCT05346328 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04887675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06484504 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06484504 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04853771 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05221008 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT06000592 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06478238 — Biomarker: CYP2U1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2U1
Study NCT05140434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05188430 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06498115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04867083 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT05362110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06375668 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT06677385 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study NCT06677255 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT04484701 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06014775 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT06014775 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT05384834 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06392451 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study NCT04712851 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT05939752 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT06255795 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06360744 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study NCT04960072 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT05547386 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05211089 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study NCT00100737 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT06154668 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05728008 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06715020 — Biomarker: TACSTD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT06718309 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06718309 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT06717828 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04969172 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study NCT05249036 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04812431 — Biomarker: NCAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCAM1; NCAM
Study NCT05226416 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04861779 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT06218303 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study NCT05290662 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT04847440 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT06107543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06405295 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT05500807 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT06302803 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04755764 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05015010 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT06677034 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT06677034 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT05348096 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT06076161 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT05896319 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT06426823 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT05377567 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT05377567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05325229 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT04603469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04998227 — Biomarker: LTBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LTBP4
Study NCT04895930 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06436144 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06436144 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT06436144 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study NCT06436144 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT05372588 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05603013 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT05932082 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05076058 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study NCT05076058 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT06307301 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT00211419 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT05407805 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06437860 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT03810898 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study NCT05985707 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05208372 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT04965298 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT05249205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05266846 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT05000216 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06292377 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06292377 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT05043181 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study NCT05043181 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06071598 — Biomarker: MFSD2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD2A; MFSD2; NLS1; HMFN0656; PP9177; UNQ300/PRO341
Study NCT06071598 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study NCT05748301 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05609825 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT05207748 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT05075083 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05766969 — Biomarker: DIAPH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: DIAPH2; DIA
Study NCT05316246 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT05255302 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05426317 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05426317 — Biomarker: Beta-2-microglobulin
Type: Safety Biomarker (SAF)
Genes: B2M; CDABP0092; HDCMA22P
Study NCT00000900 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04927481 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06243614 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT05886153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04797377 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT06252844 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT06252844 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06252844 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT05968859 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05274412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04746131 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04868942 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06448975 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04722003 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT04891835 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04891835 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT04646902 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study NCT06206824 — Biomarker: DYRK1A mRNA
Type: Predictive Biomarker (PRD)
Genes: DYRK1A; DYRK; MNB; MNBH
Study NCT05605548 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT05484466 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT05146375 — Biomarker: TGFBR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR2
Study NCT04769817 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04380155 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study NCT04380155 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study NCT06224907 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study NCT05789771 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05789771 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05255692 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study NCT06549465 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04143581 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT04143581 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT06335914 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06251622 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study NCT06314763 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT06327386 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study NCT04847570 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT00002343 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04972188 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04972188 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT06370312 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study NCT04526834 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT06124066 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06124066 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04796129 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05252208 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04853602 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study NCT04901936 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT06287021 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT05420090 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT05420090 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT05133375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05654467 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05518253 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06285149 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06007508 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT06185166 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT04581733 — Biomarker: TK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK2
Study NCT05237453 — Biomarker: BBC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BBC3; PUMA
Study NCT06238752 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06554756 — Biomarker: ANXA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D
Study NCT06149923 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT05169372 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06199908 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study NCT05302895 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04644341 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06137105 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT05685420 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study NCT04925336 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06401499 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study NCT05282875 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study NCT05402813 — Biomarker: GJB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GJB2
Study NCT05402813 — Biomarker: OTOF mRNA
Type: Predictive Biomarker (PRD)
Genes: OTOF; FER1L2
Study NCT05794880 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05588115 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study NCT05394506 — Biomarker: LMNA mRNA
Type: Predictive Biomarker (PRD)
Genes: LMNA; LMN1
Study NCT04766320 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT03633955 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT05881317 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04348617 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06416267 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study NCT04727840 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study NCT06387069 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study NCT06387069 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study NCT06319209 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03938987 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06100146 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT06010862 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT04831190 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05247684 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT06300424 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05059093 — Biomarker: FGR mRNA
Type: Predictive Biomarker (PRD)
Genes: FGR; SRC2
Study NCT06518668 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05572060 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05573542 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT05725135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05640180 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05841719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05136157 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT05869968 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05869968 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05711914 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1