AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06621901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05337787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06344845 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06467708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05046847 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study NCT05046847 — Biomarker: NTRK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK2; TRKB
Study NCT05046847 — Biomarker: NTRK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NTRK3; TRKC
Study NCT05656768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05132712 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04776018 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT05189093 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study NCT05958004 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04963985 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT05491018 — Biomarker: PIM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIM3
Study NCT04183738 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05427136 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT05077033 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT05563012 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05722873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05375968 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT03761511 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study NCT06075342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05418673 — Biomarker: Leucine-rich repeat kinase 2
Type: Pharmacodynamic Biomarker (PDY)
Genes: LRRK2; PARK8
Study NCT05774925 — Biomarker: Leucine-rich alpha-2-glycoprotein
Type: Predictive Biomarker (PRD)
Genes: LRG1; LRG
Study NCT05774925 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06052163 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study NCT05570058 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT04520711 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study NCT05111444 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05111444 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT00113776 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT05991414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05043571 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study NCT04870411 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05842616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05551715 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study NCT05288595 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05487898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05896514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04482660 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04918030 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study NCT04865276 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT05642455 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT00001069 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT06466031 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT05905120 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study NCT05666336 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study NCT04425967 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT05641870 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT06332079 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05800210 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04852328 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT06490627 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study NCT06490627 — Biomarker: BCL11A mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study NCT05970588 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04569747 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04569747 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT04932876 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06035861 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04887935 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05847192 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05759728 — Biomarker: LGR5 mRNA
Type: Predictive Biomarker (PRD)
Genes: LGR5; GPR49; GPR67
Study NCT05065957 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study NCT05361655 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05361655 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05361655 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05361655 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT05177653 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT05123040 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04382950 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05684406 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT05846243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06580535 — Biomarker: PLCE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLCE1; KIAA1516; PLCE; PPLC
Study NCT06580535 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT05764265 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05764265 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT04770389 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05645874 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study NCT05679388 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05675540 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT05294289 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study NCT05390112 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT05525416 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06366711 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06204042 — Biomarker: ITGA2B mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGA2B; GP2B; ITGAB
Study NCT06204042 — Biomarker: ITGB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGB3; GP3A
Study NCT06204042 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study NCT04992689 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04992689 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT06652425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06653712 — Biomarker: PAICS mRNA
Type: Predictive Biomarker (PRD)
Genes: PAICS; ADE2; AIRC; PAIS
Study NCT04701138 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05182567 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05388110 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06201897 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05562479 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04560166 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT06487988 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05983965 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study NCT05729399 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT05729399 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT06543745 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05367778 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT06652152 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study NCT06652152 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study NCT06396884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06313515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06313086 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05538741 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05623930 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06066346 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT05387122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04095546 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04095546 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study NCT04095546 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study NCT04095546 — Biomarker: MAOA mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOA
Study NCT04095546 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study NCT04095546 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT04628338 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study NCT06261073 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study NCT06261073 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT06261073 — Biomarker: STAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT1
Study NCT06261073 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT06261073 — Biomarker: CXCR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR3; GPR9
Study NCT06603168 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study NCT06593717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06600958 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05797987 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT06586294 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06586294 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06489496 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06158542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06186076 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05374226 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study NCT04778436 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study NCT06598995 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study NCT06588023 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04945668 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study NCT06119737 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study NCT04986306 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04986306 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study NCT06542302 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study NCT05263869 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05461976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04998331 — Biomarker: Lymphocyte activation antigen CD30
Type: Predictive Biomarker (PRD)
Genes: TNFRSF8; CD30; D1S166E
Study NCT05539768 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT04852965 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04852965 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study NCT06706687 — Biomarker: Guanine nucleotide exchange factor C9orf72
Type: Pharmacodynamic Biomarker (PDY)
Genes: C9orf72; DENND9; DENNL72
Study NCT06701903 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT04040660 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study NCT05377788 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05135000 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05135000 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT05732090 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT06333574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04920162 — Biomarker: ITGBL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGBL1; OSCP; TIED
Study NCT05138016 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT05138016 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT06156631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05148234 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT05854745 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study NCT06600347 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06095362 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT04846075 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04846075 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study NCT04846075 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT06281756 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04457323 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05839652 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06429215 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06120400 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05620628 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT06612099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05165342 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05165342 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT06001658 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study NCT05839275 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05743465 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT06419465 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04544475 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04756505 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04756505 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT06619353 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06621303 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04763577 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04763577 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT06494696 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06236126 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05094206 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05094206 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT05351437 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05502042 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study NCT05783622 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06054191 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study NCT05725070 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06169371 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06169371 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05902988 — Biomarker: KIF18A mRNA
Type: Predictive Biomarker (PRD)
Genes: KIF18A; OK/SW-cl.108
Study NCT06194864 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05140655 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05140655 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05182463 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT05863078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06544265 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04765345 — Biomarker: PCDH15 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCDH15; USH1F
Study NCT05249556 — Biomarker: Cyclin-dependent kinase-like 5
Type: Predictive Biomarker (PRD)
Genes: CDKL5; STK9
Study NCT06490913 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06136377 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06080191 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06567977 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study NCT06072326 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study NCT04981470 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05142475 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study NCT05607368 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study NCT06098612 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study NCT04931784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06567132 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study NCT06567132 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06567132 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study NCT06567132 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT06157515 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05388500 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04798027 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04798027 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05344794 — Biomarker: PNOC mRNA
Type: Predictive Biomarker (PRD)
Genes: PNOC; OFQ
Study NCT05134740 — Biomarker: MAGEA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA4; MAGE4
Study NCT05134740 — Biomarker: PRAME mRNA
Type: Predictive Biomarker (PRD)
Genes: PRAME; MAPE; OIP4
Study NCT06433609 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05079022 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05079022 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT06653881 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05280418 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study NCT05007951 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05970900 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR