AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32618695 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36573450 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 34773261 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33516014 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34106648 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33208739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33927126 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33927126 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 33927126 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 33743283 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 36137626 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 35677096 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35725294 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 32163637 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 32163637 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32163637 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32163637 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35659704 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 35659704 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35659704 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32102506 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33176381 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34808751 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 34494931 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 32585332 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 32585332 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 33871596 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36472197 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32345650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36004368 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 36004368 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36004368 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35894681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35856361 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 35856361 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 35295200 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32622071 — Biomarker: DLK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLK1; DLK
Study 32622071 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34772324 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 34543068 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35133617 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33546622 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 33624806 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 33742316 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 33398922 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 35619283 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 32178668 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 34638611 — Biomarker: DUSP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP6; MKP3; PYST1
Study 33577618 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 36266431 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33782049 — Biomarker: TFF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TFF2; SML1
Study 33782049 — Biomarker: MUC5B mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC5B; MUC5
Study 33782049 — Biomarker: REG3A mRNA
Type: Predictive Biomarker (PRD)
Genes: REG3A; HIP; PAP; PAP1
Study 33782049 — Biomarker: PAX9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX9
Study 33782049 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 33782049 — Biomarker: MUC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC2; SMUC
Study 33782049 — Biomarker: Fatty acid binding protein 1
Type: Safety Biomarker (SAF)
Genes: FABP1; FABPL
Study 33782049 — Biomarker: CDX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDX1
Study 32236953 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 32893790 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32893790 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 35712800 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35712800 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35032224 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34256199 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 34817321 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34817321 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34791009 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 35565929 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 35565929 — Biomarker: SLC2A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A5; GLUT5
Study 35565929 — Biomarker: SLC2A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A2; GLUT2
Study 35565929 — Biomarker: HMGCS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCS2
Study 35565929 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 34980609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33271319 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 36055978 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 36055978 — Biomarker: HTR3A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR3A; 5HT3R; HTR3
Study 36004653 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32291277 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 35410292 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 34383954 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35551086 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 34086911 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33579804 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study 35698432 — Biomarker: FANCC
Type: Predictive Biomarker (PRD)
Genes: FAC; FA3
Study 34670215 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34670215 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 34670215 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 34670215 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 34670215 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36216089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34002944 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 32465510 — Biomarker: CD63 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD63; MLA1; TSPAN30
Study 32465510 — Biomarker: CD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD9; MIC3; TSPAN29; GIG2
Study 32465510 — Biomarker: CD81 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD81; TAPA1; TSPAN28
Study 32465510 — Biomarker: CD24 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD24; CD24A
Study 32842812 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33491528 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33023661 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32702849 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32702849 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 32702849 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35298060 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35298060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36333720 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34022051 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 34022051 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34933950 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32383366 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32387453 — Biomarker: Epiregulin
Type: Safety Biomarker (SAF)
Genes: EREG
Study 32387453 — Biomarker: Amphiregulin
Type: Safety Biomarker (SAF)
Genes: AREG; AREGB; SDGF
Study 32387453 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 32160019 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 35701094 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 35770339 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 34174082 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 36027311 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32505529 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 32505529 — Biomarker: DMD
Type: Predictive Biomarker (PRD)
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 33740926 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 33740926 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 32223057 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33685923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32093379 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35900311 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 35900311 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 34167897 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34167897 — Biomarker: CNTNAP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTNAP3; CASPR3; KIAA1714
Study 34167897 — Biomarker: CNTN4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTN4
Study 34167897 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 34167897 — Biomarker: TNXB mRNA
Type: Predictive Biomarker (PRD)
Genes: TNXB; HXBL; TNX; TNXB1; TNXB2; XB
Study 34167897 — Biomarker: CTSE mRNA
Type: Predictive Biomarker (PRD)
Genes: CTSE
Study 34167897 — Biomarker: OLFM4 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLFM4; GW112; UNQ362/PRO698
Study 34167897 — Biomarker: KRT5 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT5
Study 34167897 — Biomarker: KRT6A mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT6A; K6A; KRT6D
Study 34167897 — Biomarker: IDO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDO2; INDOL1
Study 32299845 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34089122 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 32641220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32641220 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 36319521 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36319521 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34333030 — Biomarker: RBM20 mRNA
Type: Predictive Biomarker (PRD)
Genes: RBM20
Study 33171431 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33478571 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35072287 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 34962159 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36134465 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 616774622 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33675475 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33675475 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34706819 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34706819 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34775965 — Biomarker: PLB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLB1; PLB
Study 35430584 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 35430584 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 32842974 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 35282662 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35282662 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32833484 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 32220069 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 35544369 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33161773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33586254 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 33586254 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 33456366 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32144735 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 35651610 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 35651610 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35651610 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 32654663 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33885235 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 33885235 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 33885235 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 33840085 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 33840085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35222267 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 34235780 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34371381 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33398627 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 35147719 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36172955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32146259 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 36279690 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 35871944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32107188 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33352495 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33352495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32448782 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 32057627 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33191181 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36238481 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 36238481 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 33232476 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 33232476 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 34821105 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34821105 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 33115783 — Biomarker: FOSL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOSL1; FRA1
Study 33115783 — Biomarker: WNT11 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: WNT11
Study 33115783 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33090083 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 36384662 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 35019120 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 33321462 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34090987 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34090987 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32948369 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 36268462 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34842573 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33609741 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 32063531 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32894044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33592868 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 36306168 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 33680312 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 34840503 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32312261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32581409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35790787 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33895559 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35260450 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34735908 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35149326 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34396784 — Biomarker: PLIN5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLIN5; LSDP5; OXPAT; PAT-1
Study 35689881 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 34497027 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 34497027 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34953185 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35960116 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35411939 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 36224521 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 33161159 — Biomarker: GRHL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRHL3; SOM; TFCP2L4
Study 33685044 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33685044 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33685044 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 32772509 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36445624 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 36231251 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR