AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34299780 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32542695 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35634695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32731259 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 32976702 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33883288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33883288 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34668331 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 34668331 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 35483774 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 35483774 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 35839004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34209561 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35133634 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 36049225 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35749148 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34656412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33309774 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33309774 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34452971 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 33539664 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 35724306 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32268897 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35221104 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35221104 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33657976 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33657976 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 33657976 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 33657976 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 34407046 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33002633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33002633 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34178834 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32113648 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 32113648 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 33806616 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 32471186 — Biomarker: GSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GSTM1; GST1
Study 32471186 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32471186 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32471186 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 36253825 — Biomarker: COL7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL7A1
Study 36005859 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 36005859 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 36005859 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 32489675 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35069013 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 35069013 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 35069013 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33720857 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32441198 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 32441198 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33844054 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33161737 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33161737 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33317156 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33317156 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32034072 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33630453 — Biomarker: PHLDA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 36305926 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 34626502 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 32299513 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34319398 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34741886 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34741886 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 33715064 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33715064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32236507 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34769704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32394686 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 33233275 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 35388330 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35388330 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35388330 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35251584 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35251584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32815661 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34416229 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 35287112 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 33848805 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34123370 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33675399 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 33675399 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 33675399 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33675399 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 33175128 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 34196874 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34196874 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32985088 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32985088 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35710594 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32725873 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36293771 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 33946565 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34525119 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34324472 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34823444 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34823444 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34803913 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34803913 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34674348 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 36501009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32303180 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35362378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33129099 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33894834 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 33894834 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33310293 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33310293 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 36197757 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32048133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34772609 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 32343641 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 34028859 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 33078386 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 35124650 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 35124650 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34999143 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 35793884 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 35793884 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34279749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34322126 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32015461 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 32665162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34051428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33685838 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33685838 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32620379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34941608 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 34188449 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35066982 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 36308124 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33034157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34688944 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33152284 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33152284 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33080002 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34622567 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 33100131 — Biomarker: C7orf50 mRNA
Type: Predictive Biomarker (PRD)
Genes: C7orf50; FP15621
Study 33100131 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 33434227 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 33860313 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 34001059 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35339280 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 35339280 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35339280 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33755924 — Biomarker: KDM1A mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 33755924 — Biomarker: MAOB mRNA
Type: Predictive Biomarker (PRD)
Genes: MAOB
Study 32644875 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32644875 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32644875 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32988567 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 32988567 — Biomarker: FUT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FUT1; H; HSC
Study 34269885 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34269885 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34872102 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33607802 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33512079 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32521891 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 35427471 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 32459666 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33727797 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36460017 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32702363 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32562310 — Biomarker: miR-328a-3p
Type: Safety Biomarker (SAF)
Genes: MIR328
Study 32562310 — Biomarker: miR-20a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR20A
Study 32562310 — Biomarker: miR-17-5p
Type: Safety Biomarker (SAF)
Genes: MIR17
Study 32562310 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 32562310 — Biomarker: miR-10a
Type: Safety Biomarker (SAF)
Genes: MIR10A
Study 32562310 — Biomarker: miR-21-5p
Type: Predictive Biomarker (PRD)
Genes: MIR21
Study 32562310 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 32562310 — Biomarker: miR-26b-5p
Type: Monitoring Biomarker (MOI)
Genes: MIR26B
Study 34181712 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 34181712 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 34181712 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33141921 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 33141921 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34185278 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 35411981 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33677827 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33677827 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32914569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35872847 — Biomarker: NR3C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C2; MCR; MLR
Study 36029105 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33155824 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 33891615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33154085 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33154085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34277507 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34277507 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32444968 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 33793743 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 36416000 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 36194950 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35551978 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 32160755 — Biomarker: ACTG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTG1; ACTG
Study 33320296 — Biomarker: LARP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARP1; KIAA0731; LARP
Study 33354953 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32542644 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33327746 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33327746 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34791007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33221618 — Biomarker: DAP mRNA
Type: Predictive Biomarker (PRD)
Genes: DAP; DAP1
Study 32706428 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 35979216 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34906572 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35772861 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32512234 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33217063 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33217063 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 33235439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33235439 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35908130 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 35372992 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35372992 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32021087 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 32345356 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 35135967 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35135967 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35922124 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35922124 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35508860 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 33455137 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 33020204 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33789243 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 35859277 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32915843 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 32643361 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 32643361 — Biomarker: HPSE mRNA
Type: Predictive Biomarker (PRD)
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 32643361 — Biomarker: SYNM mRNA
Type: Predictive Biomarker (PRD)
Genes: SYNM; DMN; KIAA0353; SYN
Study 32643361 — Biomarker: KDM5D mRNA
Type: Predictive Biomarker (PRD)
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 34338105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32867959 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36209129 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34551895 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125