AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35656881 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34118980 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32423462 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34472497 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34380099 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35693290 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32823594 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 32823594 — Biomarker: ADORA2A mRNA
Type: Predictive Biomarker (PRD)
Genes: ADORA2A; ADORA2
Study 32488672 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35543679 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 36364960 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35183790 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 35183790 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34426106 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34740861 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32273183 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34045018 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34045018 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 34045018 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33356977 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34881512 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34437607 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 34937600 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 32875492 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32875492 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 32875492 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33789252 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32326719 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 35022501 — Biomarker: IVNS1ABP mRNA
Type: Predictive Biomarker (PRD)
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 32445975 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 35179758 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33097026 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 33112511 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 36348476 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33992189 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33000618 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36047376 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 33663487 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33532874 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33550259 — Biomarker: CSF1R mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF1R; FMS
Study 35914112 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33419461 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32035487 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 32035487 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32035487 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32035487 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32382922 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 32598997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35565903 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33491305 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 33491305 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 33491305 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 33491305 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 33491305 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33814890 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33814890 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 34996409 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32267348 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32267348 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 32267348 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 32267348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32267348 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33932873 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33885930 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 32049789 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32049789 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32049789 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33561514 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 37941802 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32470515 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34405256 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32813947 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32813947 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32246106 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 32246106 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 34116394 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34116394 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34116394 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35710247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35672161 — Biomarker: DPEP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPEP1; MDP; RDP
Study 34284783 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34284783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32019599 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 32019599 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 32019599 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 34165199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35010881 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34237249 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 34109364 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33308259 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36031952 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 34242246 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 34242246 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 35264075 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36450626 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 36450626 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 36450626 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34772434 — Biomarker: Plasma phenylalanine
Type: Surrogate Endpoint (SUR)
Study 34772434 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 35902299 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35902299 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35766041 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34584881 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 32514012 — Biomarker: miR-29a
Type: Monitoring Biomarker (MOI)
Genes: MIR29A
Study 34962679 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33583347 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 36058253 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33915514 — Biomarker: WARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WARS1; IFI53; WARS; WRS
Study 34888663 — Biomarker: KITLG mRNA
Type: Predictive Biomarker (PRD)
Genes: KITLG; MGF; SCF
Study 32909497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36429761 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34783882 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 34899426 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 34960005 — Biomarker: MNT mRNA
Type: Predictive Biomarker (PRD)
Genes: MNT; BHLHD3; ROX
Study 32147880 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 36036731 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 33794182 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33891907 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33302991 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 33302991 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35156255 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 35751657 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 35751657 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 33637368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32020185 — Biomarker: ISG15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ISG15; G1P2; UCRP
Study 32020185 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 32020185 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32020185 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 32020185 — Biomarker: IRF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRF9; ISGF3G
Study 32020185 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 32020185 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 32020185 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 32020185 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 32020185 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34605384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32219719 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 33310502 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 33128677 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35107113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35179770 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35321653 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32326980 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 36069668 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 33749317 — Biomarker: SCGB1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCGB1A1; CC10; CCSP; UGB
Study 33749317 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34006898 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34006898 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 34006898 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32059692 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32059692 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32059692 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 32951084 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35091170 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34902089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34476568 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34476568 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33884978 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 36052527 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36522805 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 36522805 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 36522805 — Biomarker: LCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCAT
Study 34409753 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35030335 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33413636 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34120160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34227468 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 34227468 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32419245 — Biomarker: SNN mRNA
Type: Predictive Biomarker (PRD)
Genes: SNN
Study 33835842 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34214136 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32623650 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32623650 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33308471 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 32554072 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33734131 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 34480861 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 34282598 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 34282598 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34371102 — Biomarker: PEG10 mRNA
Type: Predictive Biomarker (PRD)
Genes: PEG10; EDR; KIAA1051e; MAR2; MART2; MEF3L1; RGAG3
Study 35763041 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 35763041 — Biomarker: GPX3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX3; GPXP
Study 35763041 — Biomarker: ACTR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACTR3; ARP3
Study 35763041 — Biomarker: ARHGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGAP1; CDC42GAP; RHOGAP1
Study 35763041 — Biomarker: VPS13A mRNA
Type: Predictive Biomarker (PRD)
Genes: VPS13A; CHAC; KIAA0986
Study 35763041 — Biomarker: KALRN mRNA
Type: Predictive Biomarker (PRD)
Genes: KALRN; DUET; DUO; HAPIP; TRAD
Study 33951448 — Biomarker: GSS mRNA
Type: Predictive Biomarker (PRD)
Genes: GSS
Study 32552731 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 33028396 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 33028396 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35733213 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 33674988 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 32333877 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35187164 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32987917 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34438242 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 34438242 — Biomarker: TLE4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLE4; GRG4; KIAA1261
Study 32798050 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 32798050 — Biomarker: GNL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNL3; E2IG3; NS
Study 32243009 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32243009 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33207093 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36318438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32672829 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 36027496 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 36027496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33640203 — Biomarker: Guanine nucleotide exchange factor C9orf72
Type: Pharmacodynamic Biomarker (PDY)
Genes: C9orf72; DENND9; DENNL72
Study 33640203 — Biomarker: G2E3 mRNA
Type: Predictive Biomarker (PRD)
Genes: G2E3; KIAA1333
Study 33640203 — Biomarker: Ataxin-3
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 33640203 — Biomarker: CLCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLCN3
Study 33640203 — Biomarker: GGNBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGNBP2; LCRG1; LZK1; ZNF403
Study 32387055 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35499570 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 34531304 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 35351253 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34380811 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34774052 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33302654 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33302654 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36116480 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34032151 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34032151 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35737911 — Biomarker: CLEC4D mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC4D; CLECSF8; MCL
Study 35737911 — Biomarker: ZFP36 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 35737911 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32503727 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8