AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35190584 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 34493431 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34493431 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36394838 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 34347093 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 34347093 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 36215414 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36215414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33350678 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 32466446 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32466446 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35484607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32826114 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 32559474 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32559474 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35264106 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32627438 — Biomarker: F7 mRNA
Type: Predictive Biomarker (PRD)
Genes: F7
Study 34389701 — Biomarker: SIRT6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIRT6; SIR2L6
Study 34086190 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34086190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32107818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34048641 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34086518 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 34701458 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32924561 — Biomarker: MMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMP2; CLG4A
Study 32924561 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 33318079 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32960272 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 32960272 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35030530 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33835084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35392908 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32051972 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33349641 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32952230 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 36137691 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 33657007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36278359 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33096356 — Biomarker: AFF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 36401445 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33955628 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 33078649 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36375479 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33592815 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 36159170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36159170 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 36159170 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32037254 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32248805 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32248805 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32198616 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33283766 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36334050 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 34438976 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34438976 — Biomarker: Bacterial count
Type: Surrogate Endpoint (SUR)
Study 34397104 — Biomarker: TNR mRNA
Type: Predictive Biomarker (PRD)
Genes: TNR
Study 32032923 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32032923 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 33784428 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35280426 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36239883 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33572416 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 33332813 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32861377 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35320494 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35320494 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32521538 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34825613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32062048 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 34971614 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 32127255 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34402887 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33509035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32959586 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 32959586 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34643650 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 34643650 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 34643650 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 35775789 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35637845 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35637845 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35637845 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33686683 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 33686683 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 36197213 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 35238614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33448139 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 33448139 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 33448139 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 33448139 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33448139 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33448139 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32815405 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 32815405 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 32815405 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 35451612 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 33386040 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 33982141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35401282 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 35401282 — Biomarker: L3MBTL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: L3MBTL4
Study 33663489 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35397664 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 35397664 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 32210349 — Biomarker: Protein AMBP
Type: Safety Biomarker (SAF)
Genes: AMBP; HCP; ITIL
Study 33450335 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33450335 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34897499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35275761 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34508090 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32514677 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34729862 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35073825 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33469276 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35048253 — Biomarker: NES mRNA
Type: Predictive Biomarker (PRD)
Genes: NES; Nbla00170
Study 36136603 — Biomarker: MYOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 36136603 — Biomarker: MYF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYF5; BHLHC2
Study 36136603 — Biomarker: MYF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYF6; BHLHC4; MRF4
Study 33040817 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33040817 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34130243 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 616026366 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35216619 — Biomarker: LAMB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMB2; LAMS
Study 35216619 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 33082181 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35582957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34559182 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33763720 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33832307 — Biomarker: ITIH3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITIH3
Study 34995935 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34995935 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34995935 — Biomarker: Argininosuccinate synthase
Type: Safety Biomarker (SAF)
Genes: ASS1; ASS
Study 33256760 — Biomarker: KL mRNA
Type: Predictive Biomarker (PRD)
Genes: KL
Study 36168187 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 36168187 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 36168187 — Biomarker: TTLL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TTLL5; KIAA0998; STAMP
Study 35176163 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 35176163 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 33785752 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33785752 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34237809 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 34237809 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34237809 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35038612 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33459692 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 34232005 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 36241502 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32090516 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 32131656 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32131656 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 32131656 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32131656 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 34801353 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33989763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35685661 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35685661 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 35685661 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35313858 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33125033 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 32583886 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34528669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34250456 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34271286 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 36237142 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 34613430 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 34613430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35030040 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 32961319 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32961319 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 32892604 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32892604 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33422518 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33355818 — Biomarker: PIR mRNA
Type: Predictive Biomarker (PRD)
Genes: PIR
Study 34787952 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33219136 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34637055 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 34637055 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 36137949 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 33847022 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 34785763 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 33539582 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32305093 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 32807252 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32807252 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 32807252 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 32807252 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 32807252 — Biomarker: Small-inducible cytokine A11
Type: Predictive Biomarker (PRD)
Genes: CCL11; SCYA11
Study 32807252 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 35813842 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 35813842 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 35813842 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 35813842 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 35813842 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34181564 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33290405 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33290405 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32078064 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 32078064 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 32576559 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32186048 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35997173 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 35997173 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35997173 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32964434 — Biomarker: NUCB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB2; NEFA
Study 33682286 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 32698903 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 34520506 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33168966 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 33168966 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33168966 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 33168966 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 32358398 — Biomarker: RASA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RASA1; GAP; RASA
Study 32507863 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 34508654 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34508654 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33353965 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35292232 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 34371004 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 34371004 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32902075 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 33560891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34459400 — Biomarker: DNER mRNA
Type: Predictive Biomarker (PRD)
Genes: DNER; BET; UNQ262/PRO299
Study 32619792 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34748169 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 32885808 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32885808 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35090047 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33577375 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 32084431 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 32084431 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 32084431 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32379635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34324430 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35176141 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 32952009 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32952009 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32952009 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34229554 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35240966 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32156204 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)