AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32965623 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32560181 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 32560181 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 35272404 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 34702773 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 34702773 — Biomarker: FCGR1A mRNA
Type: Predictive Biomarker (PRD)
Genes: FCGR1A; FCG1; FCGR1; IGFR1
Study 34702773 — Biomarker: PTK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTK2; FAK; FAK1
Study 35898448 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 35898448 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32853242 — Biomarker: AHR mRNA
Type: Predictive Biomarker (PRD)
Genes: AHR; BHLHE76
Study 33740332 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32817282 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 32817282 — Biomarker: NFKBIA mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 32767163 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35634285 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35634285 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 35634285 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36031855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32646282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35405088 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35405088 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35405088 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35405088 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 33711991 — Biomarker: COMP mRNA
Type: Predictive Biomarker (PRD)
Genes: COMP
Study 33711991 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33711991 — Biomarker: CXCL16 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 33711991 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 32814717 — Biomarker: PITX2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PITX2; ARP1; RGS; RIEG; RIEG1
Study 34508594 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36051928 — Biomarker: PRND mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PRND; DPL; UNQ1830/PRO3443
Study 34897099 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 33789909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32067585 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33421309 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 36294463 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32698457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34014615 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 33526730 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33526730 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35796876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32434467 — Biomarker: ACAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAT1; ACAT; MAT
Study 32206987 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32206987 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32206987 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34465810 — Biomarker: SMOX mRNA
Type: Predictive Biomarker (PRD)
Genes: SMOX; C20orf16; SMO; UNQ3039/PRO9854
Study 33302685 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33302685 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33302685 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34225270 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 32198596 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 32198596 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 33801767 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34864766 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33112481 — Biomarker: REG1B mRNA
Type: Predictive Biomarker (PRD)
Genes: REG1B; PSPS2; REGL
Study 32482611 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 35050952 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32842644 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34841615 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 34841615 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 34841615 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34735643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32596729 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34160347 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 33066857 — Biomarker: SP9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP9
Study 33066857 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 32473678 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 2012036615 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 2012036615 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 2012036615 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34035100 — Biomarker: NUBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBP1; NBP; NBP1
Study 36378768 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35852035 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 35852035 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35135037 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 35135037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35473780 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32919280 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 32919280 — Biomarker: APOA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOA1
Study 34582653 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35576286 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33940347 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 34082792 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 36345809 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36130612 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35575766 — Biomarker: LSR mRNA
Type: Predictive Biomarker (PRD)
Genes: LSR; ILDR3; LISCH
Study 32379982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34536714 — Biomarker: CAST mRNA
Type: Predictive Biomarker (PRD)
Genes: CAST
Study 34028012 — Biomarker: S100B mRNA
Type: Predictive Biomarker (PRD)
Genes: S100B
Study 34028012 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32503652 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32503652 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35949922 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33592011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32416072 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 35377723 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34505019 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 33861738 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 33861738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33861738 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 33861738 — Biomarker: IL37 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
Study 32434362 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 33992812 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33558193 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33481251 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34290294 — Biomarker: FLNA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FLNA; FLN; FLN1
Study 34290294 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 34290294 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 34590570 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 36220354 — Biomarker: CALD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CALD1; CAD; CDM
Study 33856337 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 32103280 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 35035537 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 615709281 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 34464358 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34085881 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32529788 — Biomarker: HBEGF mRNA
Type: Predictive Biomarker (PRD)
Genes: HBEGF; DTR; DTS; HEGFL
Study 36285551 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32701239 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 34924360 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35713772 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 35241098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34247263 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35180190 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32357133 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 36216962 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35501751 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 616117228 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 616117228 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 36062851 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33517316 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35286033 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 34902765 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34902765 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34902765 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35079806 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 35079806 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33408462 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32928328 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32928328 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33927176 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 33927176 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33927176 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35332042 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 35472112 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 33799486 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 33965556 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 33965556 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 33965556 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33965556 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33965556 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33965556 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35783486 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34237271 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 32876804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32876804 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32876804 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35904638 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35904638 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33159256 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32862697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32448171 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32931308 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34607479 — Biomarker: ITIH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITIH4; IHRP; ITIHL1; PK120; PRO1851
Study 33788480 — Biomarker: HOXA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA10; HOX1H
Study 33455938 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32517739 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 35791797 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 34374027 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 33089619 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 35142560 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34059090 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 36038984 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33093133 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32313940 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35102203 — Biomarker: GSR mRNA
Type: Predictive Biomarker (PRD)
Genes: GSR; GLUR; GRD1
Study 36401133 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 36401133 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33499572 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 33277845 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 33277845 — Biomarker: Aminopeptidase N
Type: Safety Biomarker (SAF)
Genes: ANPEP; APN; CD13; PEPN
Study 34344672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34076333 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35765728 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32235839 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34180245 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 32086599 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 35356935 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35873768 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 33115487 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34420261 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 34420261 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 33855355 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36260786 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 36288581 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 33824389 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 33824389 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 36038003 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 34606933 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 34491446 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 33755280 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 32730216 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33794293 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 33794293 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 33794293 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 33794293 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 32046384 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 32046384 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 32046384 — Biomarker: KLF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF9; BTEB; BTEB1
Study 32046384 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32046384 — Biomarker: KLF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLF4; EZF; GKLF
Study 32046384 — Biomarker: DKK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DKK1; UNQ492/PRO1008
Study 35557278 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 32827501 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 32810383 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 35960044 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36163987 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 36163987 — Biomarker: IRAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IRAK1; IRAK
Study 36163987 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 34533774 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34533774 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33605982 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 32173896 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32173896 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36386386 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32544773 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 35416361 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 33390054 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32447799 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 32447799 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33540180 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33852720 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 33852720 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 33852720 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 33852720 — Biomarker: CD8A mRNA
Type: Predictive Biomarker (PRD)
Genes: CD8A; MAL
Study 33852720 — Biomarker: CRTAM mRNA
Type: Predictive Biomarker (PRD)
Genes: CRTAM
Study 33852720 — Biomarker: GZMA mRNA
Type: Predictive Biomarker (PRD)
Genes: GZMA; CTLA3; HFSP
Study 33852720 — Biomarker: ADGRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADGRG1; GPR56; TM7LN4; TM7XN1; UNQ540/PRO1083