AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 36246136 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33399016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35226532 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 34349841 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 32682457 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33288325 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 33023671 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33704435 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33982936 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 36078648 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33205064 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 33205064 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 34391872 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 32066598 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 34853883 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32466016 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 34325645 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35161508 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34580638 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35254967 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 32848379 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33217147 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34002707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33941941 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34993836 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32574096 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33653749 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 32580710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35012310 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33306213 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 33306213 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 33306213 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 32211084 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34918714 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34918714 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32894102 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34861767 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 34861767 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 34861767 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 34861767 — Biomarker: TIGIT mRNA
Type: Predictive Biomarker (PRD)
Genes: TIGIT; VSIG9; VSTM3
Study 34861767 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 34861767 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36137670 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32591103 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 32133391 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35411792 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 34942595 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33065552 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 35406083 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33278859 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32066487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32066487 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32066487 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33962504 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33962504 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 35218194 — Biomarker: PNPLA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: PNPLA3; ADPN; C22orf20
Study 34148146 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34148146 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 33109190 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35404684 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35266296 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 35320921 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 32852139 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 32976051 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 34346827 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32958697 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33334450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35689890 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35689890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35689890 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 35689890 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35689890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33075197 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33887445 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32755035 — Biomarker: CYCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CYCS; CYC
Study 34256413 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33010038 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34264000 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33955183 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 616774451 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32568876 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36102236 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 34499904 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32279416 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 32279416 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 36316511 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 32376724 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 35590219 — Biomarker: KHK mRNA
Type: Predictive Biomarker (PRD)
Genes: KHK
Study 33542908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33894583 — Biomarker: DCT mRNA
Type: Predictive Biomarker (PRD)
Genes: DCT; TYRP2
Study 35781044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32334632 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 32571411 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35089798 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35089798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34131157 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 35441463 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35441463 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 37119361 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33674633 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 33674633 — Biomarker: miR-29a
Type: Monitoring Biomarker (MOI)
Genes: MIR29A
Study 34537805 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34756997 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 34221381 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 34221381 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 34221381 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35830361 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33827478 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 35407483 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 36216304 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36216304 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 32675599 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34636474 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 36054180 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 36054180 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 34157357 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 35941553 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 32324902 — Biomarker: SLC5A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A8; AIT; SMCT; SMCT1
Study 32516351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32221489 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34425869 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34425869 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34425869 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35459911 — Biomarker: A2M mRNA
Type: Predictive Biomarker (PRD)
Genes: A2M; CPAMD5; FWP007
Study 36296939 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 33755118 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33266499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33266499 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33266499 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33531690 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 32722799 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 32722799 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34105796 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32516725 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 32516725 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 34371826 — Biomarker: RASGRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RASGRP1; RASGRP
Study 34371826 — Biomarker: BIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BIN1; AMPHL
Study 34371826 — Biomarker: LEF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LEF1
Study 34371826 — Biomarker: ANXA6 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANXA6; ANX6
Study 34371826 — Biomarker: LRRN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRRN3; Nbla10363; UNQ194/PRO220
Study 34371826 — Biomarker: PRKCQ mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKCQ; PRKCT
Study 35405087 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32894227 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 36344933 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33164978 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 32100261 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 35816301 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32795310 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 32795310 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 35180696 — Biomarker: VIM mRNA
Type: Predictive Biomarker (PRD)
Genes: VIM
Study 35158207 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34371884 — Biomarker: TXNIP mRNA
Type: Predictive Biomarker (PRD)
Genes: TXNIP; VDUP1
Study 34371884 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 34371884 — Biomarker: AGER mRNA
Type: Predictive Biomarker (PRD)
Genes: AGER; RAGE
Study 34371884 — Biomarker: MLXIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MLXIP; BHLHE36; KIAA0867; MIR; MONDOA
Study 34371884 — Biomarker: MAFF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAFF
Study 34371884 — Biomarker: MAFG mRNA
Type: Predictive Biomarker (PRD)
Genes: MAFG
Study 34371884 — Biomarker: NCF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCF1; NOXO2; SH3PXD1A
Study 34371884 — Biomarker: FTH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FTH1; FTH; FTHL6; OK/SW-cl.84; PIG15
Study 34371884 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 34371884 — Biomarker: TKT mRNA
Type: Predictive Biomarker (PRD)
Genes: TKT
Study 36006634 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33641601 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 33641601 — Biomarker: Serum intact parathyroid hormone
Type: Surrogate Endpoint (SUR)
Study 33641601 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 33641601 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 33641601 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 33641601 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34919613 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32067040 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32358544 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32358544 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34597366 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 33655432 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34048947 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32465052 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 33985364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33985364 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35658056 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 33201520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32599655 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 33239044 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 33019798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33989025 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 32804188 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34648082 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 33402230 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 32201120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36109142 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36109142 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36109142 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35201920 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 36359816 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37715688 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 33397395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33397395 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 32513313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32513313 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36018224 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 36018224 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 33528102 — Biomarker: EBF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EBF1; COE1; EBF
Study 35942633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35942633 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34105213 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 35172870 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 34033301 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 32265129 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33415354 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34020929 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 32611442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32611442 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33709262 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33709262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32065311 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 33422683 — Biomarker: SLC12A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC12A3; NCC; TSC
Study 35951718 — Biomarker: TES mRNA
Type: Predictive Biomarker (PRD)
Genes: TES
Study 35814746 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32178978 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35850080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32951632 — Biomarker: CENPJ mRNA
Type: Predictive Biomarker (PRD)
Genes: CENPJ; CPAP; LAP; LIP1
Study 35899378 — Biomarker: ICOSLG mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 35899378 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 35899378 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32654554 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32407137 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 35549845 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34951009 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 34951009 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 34951009 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 34951009 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 34719101 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 32350903 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32350903 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32350903 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2