AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34531823 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 36482620 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32028411 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 33524876 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33524876 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 32988721 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32067098 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 35576915 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32302757 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 35354306 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 32862592 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32862592 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35180646 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 33781141 — Biomarker: LPAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPAR1; EDG2; LPA1
Study 33781141 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32106642 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34582449 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 36153583 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 36153583 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 33381795 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33381795 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34482412 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 32366244 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32452085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34159412 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35765946 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35086141 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 35086141 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33190420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32176166 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33720089 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 36315917 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36315917 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 33858668 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 32481510 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 33333055 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 33333055 — Biomarker: Leucine-rich alpha-2-glycoprotein
Type: Predictive Biomarker (PRD)
Genes: LRG1; LRG
Study 32697889 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 35908849 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 35753247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34171465 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32062371 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32062371 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32062371 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 32584367 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34836179 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 33418429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32354366 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36030888 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 33145643 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33145643 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36152382 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 33099812 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35057420 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33506054 — Biomarker: SLPI mRNA
Type: Predictive Biomarker (PRD)
Genes: SLPI; WAP4; WFDC4
Study 33506054 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 33506054 — Biomarker: BPIFA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BPIFA1; LUNX; NASG; PLUNC; SPLUNC1; SPURT; UNQ787/PRO1606
Study 33506054 — Biomarker: BPIFB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
Study 33506054 — Biomarker: BPIFB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BPIFB2; BPIL1; C20orf184; LPLUNC2; UNQ2489/PRO5776
Study 33506054 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 33506054 — Biomarker: LYZ mRNA
Type: Predictive Biomarker (PRD)
Genes: LYZ; LZM
Study 33506054 — Biomarker: S100A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A8; CAGA; CFAG; MRP8
Study 33506054 — Biomarker: Calgranulin B
Type: Predictive Biomarker (PRD)
Genes: S100A9; CAGB; CFAG; MRP14
Study 33506054 — Biomarker: H2BC10 mRNA
Type: Predictive Biomarker (PRD)
Genes: H2BC4; H2BFL; HIST1H2BC;; H2BC6; H2BFH; HIST1H2BE;; H2BC7; H2BFG; HIST1H2BF;; H2BC8; H2BFA; HIST1H2BG;; H2BC10; H2BFK; HIST1H2BI
Study 32705177 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 35139273 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 34617567 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 34617567 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34375712 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 36199177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34116144 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 36372355 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 35606099 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34302571 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33545781 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 36163903 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 36163903 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 34521461 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35687604 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 32808239 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32808239 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33668309 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 33668309 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 33668309 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 33274466 — Biomarker: AQP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP1; CHIP28
Study 33274466 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 33274466 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 34843657 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33712909 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 33949052 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 36357459 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34154321 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33653118 — Biomarker: KCNQ2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ2
Study 33689525 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33689525 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33689525 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33073938 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33073938 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32878112 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32386001 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34383143 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32967799 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 34409637 — Biomarker: NT5E mRNA
Type: Predictive Biomarker (PRD)
Genes: NT5E; NT5; NTE
Study 34409637 — Biomarker: GLDC mRNA
Type: Predictive Biomarker (PRD)
Genes: GLDC; GCSP
Study 34409637 — Biomarker: NUDT17 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUDT17
Study 34409637 — Biomarker: MSH4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSH4
Study 34409637 — Biomarker: PTER mRNA
Type: Predictive Biomarker (PRD)
Genes: PTER
Study 34409637 — Biomarker: SERPINB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB6; PI6; PTI
Study 32513294 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 33812699 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 33812699 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 33812699 — Biomarker: SLC22A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC22A1; OCT1
Study 33812699 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 33812699 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 33812699 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 36198259 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32466773 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33536010 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34472504 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 34472504 — Biomarker: PPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPA1; IOPPP; PP
Study 33070154 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 35752551 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 35126199 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33727659 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33727659 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 32419549 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 32419549 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 32419549 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33710344 — Biomarker: IL1R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 33710344 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 32606097 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33802559 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 33067279 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 35192016 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 34776140 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 35579951 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35579951 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33675447 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33675447 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33290971 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33290971 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32529506 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34709363 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34709363 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34969074 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 35365148 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35610083 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35610083 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32046467 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 35909384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33222598 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34888612 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33638625 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 35793110 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34526104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34526104 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 32998940 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 32998940 — Biomarker: TMEM37 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM37; PR
Study 32998940 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 32998940 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32998940 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34450192 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32804345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32644829 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 32644829 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32644829 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33188651 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33188651 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 33236509 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33236509 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33236509 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32604288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 616497285 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32348985 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32348985 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33880021 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33880021 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35134817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35075138 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35075138 — Biomarker: FLT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT1; FLT; FRT; VEGFR1
Study 35075138 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 35110894 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35341689 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32492138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35334836 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 32673309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33646464 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32134035 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 35623869 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35623869 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33822328 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 33850272 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34787298 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34117621 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32770972 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32770972 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32770972 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33752070 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33752070 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 33752070 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study 33752070 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study 32303198 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 33616345 — Biomarker: Connecting peptide
Type: Safety Biomarker (SAF)
Genes: AHSG; FETUA; PRO2743
Study 33616345 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33616345 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33616345 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33616345 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32101256 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 32975061 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 35188581 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35188581 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32147955 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 35227250 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 34464996 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 32393654 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33769656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32876488 — Biomarker: RETN mRNA
Type: Predictive Biomarker (PRD)
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 32876488 — Biomarker: PTPRU mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPRU; FMI; PCP2; PTPRO
Study 32876488 — Biomarker: STXBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STXBP2; UNC18B
Study 32876488 — Biomarker: XAB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: XAB2; HCNP; KIAA1177; SYF1; PP3898
Study 34174137 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34146045 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33970955 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34164944 — Biomarker: SRI mRNA
Type: Predictive Biomarker (PRD)
Genes: SRI
Study 35067488 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32567372 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33378515 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 35760393 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 35760393 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 32357239 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33507202 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36370961 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 36370961 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34684324 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP