AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34706171 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 32591862 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 32591862 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 32591862 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 32591862 — Biomarker: STAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: STAT2
Study 32591862 — Biomarker: TPSAB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPSAB1; TPS1; TPS2; TPSB1
Study 32591862 — Biomarker: CD9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD9; MIC3; TSPAN29; GIG2
Study 32591862 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 32361863 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 35383463 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32779386 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 32732928 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32526634 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 35226357 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 32218418 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32218418 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 32218418 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 35897081 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 36253609 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32216086 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 32216086 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 35387813 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35387813 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33617937 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33617937 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 33617937 — Biomarker: PGR mRNA
Type: Predictive Biomarker (PRD)
Genes: PGR; NR3C3
Study 33617937 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 33617937 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32537688 — Biomarker: PF4 mRNA
Type: Predictive Biomarker (PRD)
Genes: PF4; CXCL4; SCYB4
Study 36117491 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 36117491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36117491 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36117491 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34154588 — Biomarker: CDS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDS1; CDS
Study 34154588 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 34037436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33884504 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 32107364 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36321877 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 35355382 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34003273 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 33103934 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 34015499 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34015499 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35177279 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 35091786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32458096 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33100181 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 33825687 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 32633067 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 35255096 — Biomarker: MALT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MALT1; MLT
Study 34006388 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 34006388 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35093682 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35093682 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32349193 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34263442 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 36464887 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 33160420 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 33160420 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 35115099 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 34462278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32220893 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32220893 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 32220893 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 32220893 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 33186735 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35462552 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 35462552 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35462552 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 33284944 — Biomarker: MYD88 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYD88
Study 33284944 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 34143220 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34769797 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34769797 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32203207 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32289283 — Biomarker: HSPA1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 32289283 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 32289283 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33485455 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33485455 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 33738615 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33738615 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36102618 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 32869576 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 35675149 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33599720 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32232971 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 35701314 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32747206 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 34959932 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33278328 — Biomarker: Serum asparaginase
Type: Surrogate Endpoint (SUR)
Study 32668483 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 32603956 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35030255 — Biomarker: Platelet count response
Type: Surrogate Endpoint (SUR)
Study 34210725 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 32061969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32061969 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35636031 — Biomarker: MCCC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCCC2; MCCB
Study 36357559 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33149205 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 36361100 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34933842 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 36049647 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 34791761 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34910825 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 33660386 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33660386 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 36031405 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 35177687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32270927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34850043 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34272817 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36180564 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 36180564 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 36180564 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 36180564 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35956364 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33607831 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34564893 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34686472 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 32469156 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32469156 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35986303 — Biomarker: SIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SIT1; SIT
Study 33453159 — Biomarker: AMT mRNA
Type: Predictive Biomarker (PRD)
Genes: AMT; GCST
Study 33401126 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 35848047 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33303340 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 33303340 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 33387724 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33387724 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33387724 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35621697 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 36006643 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL
Study 36006643 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36293723 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34351939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35513777 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32869151 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 33715235 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33275596 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33275596 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33521870 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33521870 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 33032658 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35147085 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35147085 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34813098 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33210302 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33210302 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35279081 — Biomarker: Sputum culture conversion to negative
Type: Surrogate Endpoint (SUR)
Study 32764524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34425554 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 32043762 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32043762 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36286977 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 34454754 — Biomarker: TJP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TJP1; ZO1
Study 34454754 — Biomarker: CLDN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN2; PSEC0059; SP82; UNQ705/PRO1356
Study 34454754 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 32915962 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36093398 — Biomarker: VIP mRNA
Type: Predictive Biomarker (PRD)
Genes: VIP
Study 34737220 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34737220 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 34737220 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34737220 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36030971 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 33269836 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33269836 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33539944 — Biomarker: Extracellular signal-regulated kinase
Type: Pharmacodynamic Biomarker (PDY)
Study 33539944 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32238947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35089384 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 35089384 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 35089384 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35438829 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33605981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35871120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35871120 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 34670954 — Biomarker: S100A12 mRNA
Type: Predictive Biomarker (PRD)
Genes: S100A12
Study 33394979 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 35380689 — Biomarker: Hemagglutination inhibition antibody
Type: Surrogate Endpoint (SUR)
Study 32285590 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 35057457 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 35057457 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34959951 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35030036 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 35030036 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 32203933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34217854 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 34217854 — Biomarker: GLS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS2; GA
Study 34853156 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33485635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33485635 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33485635 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34131267 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 34131267 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34591808 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 34111277 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 33280041 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32627474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32871952 — Biomarker: GAT1
Type: Safety Biomarker (SAF)
Genes: SLC6A1; GABATR; GABATHG; GAT-1; hGAT-1
Study 32871952 — Biomarker: SYT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SYT1; SVP65; SYT
Study 32871952 — Biomarker: COL19A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL19A1
Study 32871952 — Biomarker: RIMS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RIMS2; KIAA0751; RAB3IP3; RIM2
Study 32871952 — Biomarker: COL1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A2
Study 33589582 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34914243 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34914243 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33417292 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33405474 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 32633217 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 34489928 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36107991 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35129111 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32883514 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 34530759 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 34530759 — Biomarker: WAP four-disulfide core domain protein 2
Type: Predictive Biomarker (PRD)
Genes: WFDC2; HE4; WAP5
Study 34530759 — Biomarker: Osteopontin
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SPP1; BNSP; OPN; PSEC0156
Study 34530759 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 33651633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33904792 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 32909675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32909675 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 36081429 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32712034 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 33727257 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 32267058 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32750212 — Biomarker: PPP3R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP3R1; CNA2; CNB
Study 34407884 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34407884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32242215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32242215 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2