AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 38213637 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 38213637 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38213637 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38213637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38214149 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 38214149 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 38214539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38214552 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38215355 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 38215395 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 38215438 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 38215546 — Biomarker: NOX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOX4; RENOX
Study 38216290 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38216319 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 38216543 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38216554 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 38216566 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 38216728 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 38216728 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 38216766 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38216766 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38216831 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 38216905 — Biomarker: Beta-secretase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: BACE1; BACE; KIAA1149
Study 38216971 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 38216985 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38217361 — Biomarker: RTEL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 38218924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38218979 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 38218979 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 38218979 — Biomarker: CD47 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD47; MER6
Study 38220413 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38220592 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 38220592 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 38222312 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38222312 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 38224415 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 38224478 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38224478 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 38225549 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 38225551 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 38225579 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38225633 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 38226507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38226511 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38226511 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38227033 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38227033 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 38227034 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 38227034 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 38227621 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 38227933 — Biomarker: CCR9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR9; GPR28
Study 38227933 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38228054 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 38228467 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 38229199 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 38231282 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 38231590 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38231777 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38232095 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38232336 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 38232336 — Biomarker: NRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: NRAS; HRAS1
Study 38232682 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38232682 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38232692 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38233075 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38233075 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 38233512 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38233570 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 38233575 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38233586 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 38233586 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 38233608 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 38233810 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38233810 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 38233816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38233816 — Biomarker: ARHGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF5; TIM
Study 38233908 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38235421 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38235421 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38235512 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38235741 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 38236249 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 38236249 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38236575 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38236581 — Biomarker: HOXB13 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXB13
Study 38236581 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 38236590 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38236590 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38236602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38237075 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 38237077 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 38237620 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 38237675 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 38237796 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 38238055 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 38238060 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 38238620 — Biomarker: NUBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUBP1; NBP; NBP1
Study 38238616 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 38238759 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 38238788 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 38240024 — Biomarker: SOCS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOCS1; SSI1; TIP3
Study 38240024 — Biomarker: CD207 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD207; CLEC4K
Study 38240024 — Biomarker: IL37 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
Study 38240778 — Biomarker: MOXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 38240778 — Biomarker: NTM mRNA
Type: Predictive Biomarker (PRD)
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 38240843 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38240916 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38241058 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 38241058 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 38241059 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38241354 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 38241661 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38242333 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 38242575 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 38242717 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38242720 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38242720 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38243011 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 38243752 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 38243906 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 38243998 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study 38244708 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38244708 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 38245818 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38246526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38247010 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38247384 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 38249336 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 38249987 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 38250270 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 38250270 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 38250275 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 38251524 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38251563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38251576 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 38251576 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38251576 — Biomarker: FCGR2B
Type: Predictive Biomarker (PRD)
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 38251590 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 38251590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38252211 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38252211 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 38252907 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38252910 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 38252910 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38253245 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38253701 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 38253914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38253933 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 38254073 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 38254266 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 38254266 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 38254266 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 38258270 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38258270 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38258362 — Biomarker: HPR mRNA
Type: Predictive Biomarker (PRD)
Genes: HPR
Study 38258369 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 38258566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38258600 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 38259250 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 38259304 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 38259304 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38260556 — Biomarker: C8G mRNA
Type: Predictive Biomarker (PRD)
Genes: C8G
Study 38260556 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 38260556 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 38260556 — Biomarker: PPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1
Study 38260556 — Biomarker: KRT9 mRNA
Type: Predictive Biomarker (PRD)
Genes: KRT9
Study 38260556 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 38260556 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38260556 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 38260663 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 38261313 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 38261316 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 38261444 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 38261958 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38261958 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 38261983 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 38262005 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38262242 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38262617 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38263021 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 38263021 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38263321 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 38263321 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 38263353 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study 38263486 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38263652 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 38263652 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 38264276 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38264520 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 38264697 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38265633 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38266104 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 38266104 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 38266104 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 38266154 — Biomarker: Coagulation factor VIII
Type: Predictive Biomarker (PRD)
Genes: F8; F8C
Study 38267108 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 38267108 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 38267533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38267634 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38267987 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 38267987 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 38268157 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 38268157 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38269049 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38269302 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 38270822 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 38271925 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38272375 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 38272555 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38272555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38272561 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38273214 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38273214 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38273319 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 38273390 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38273408 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 38273597 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38273597 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38273625 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 38273639 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 38274236 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38274292 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 38274389 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 38274398 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 38274398 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 38274398 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1