AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 34558847 — Biomarker: Type I cytoskeletal 18 Keratin
Type: Safety Biomarker (SAF)
Genes: KRT18; CYK18; PIG46
Study 34558847 — Biomarker: Glutamate dehydrogenase
Type: Safety Biomarker (SAF)
Study 34907265 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34907265 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34907265 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 34907265 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36315274 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32646638 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35360482 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 35560310 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 34023008 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 34023008 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 34023008 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study 34001166 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 33932804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33040829 — Biomarker: TPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPT1
Study 33040829 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 34900568 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36304175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36304175 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34803922 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 616062932 — Biomarker: RAD51AP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51AP1; PIR51
Study 33016996 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34344482 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32475902 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 33769243 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33769243 — Biomarker: GPX4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPX4
Study 33769243 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33769243 — Biomarker: PRDX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PRDX1; PAGA; PAGB; TDPX2
Study 33769243 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 33769243 — Biomarker: BAX mRNA
Type: Predictive Biomarker (PRD)
Genes: BAX; BCL2L4
Study 32902561 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 35747142 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34962665 — Biomarker: TNF-related weak inducer of apoptosis
Type: Predictive Biomarker (PRD)
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 34962665 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35818255 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34416294 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 616222542 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 616222542 — Biomarker: VASP mRNA
Type: Predictive Biomarker (PRD)
Genes: VASP
Study 35672455 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32737420 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32737420 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32737420 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32969531 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34959861 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34959861 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 35836365 — Biomarker: Dermal blood flow
Type: Pharmacodynamic Biomarker (PDY)
Study 32290852 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33640422 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33640422 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 32555927 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33804123 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33734306 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33734306 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35501626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33270531 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 32869659 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32869659 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34903696 — Biomarker: NRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRP1; NRP; VEGF165R
Study 34903696 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32506135 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33586539 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32275191 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32275191 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35896969 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32101262 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34275501 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 36195338 — Biomarker: OAT mRNA
Type: Predictive Biomarker (PRD)
Genes: OAT
Study 34751928 — Biomarker: TAAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAAR1; TA1; TAR1; TRAR1
Study 34751928 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 34105866 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34082176 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32773737 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34128083 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 36368677 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34006044 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 34006044 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32902207 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 32902207 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 33991471 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35379247 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33335310 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 32867830 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33543797 — Biomarker: OMG mRNA
Type: Predictive Biomarker (PRD)
Genes: OMG; OMGP
Study 33248560 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 36313769 — Biomarker: IGF2BP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF2BP2; IMP2; VICKZ2
Study 36313769 — Biomarker: DPYSL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPYSL5; CRMP5; ULIP6
Study 36313769 — Biomarker: PDHX mRNA
Type: Predictive Biomarker (PRD)
Genes: PDHX; PDX1
Study 36313769 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 36313769 — Biomarker: COBLL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COBLL1; KIAA0977
Study 36313769 — Biomarker: SLC17A9 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC17A9; C20orf59
Study 36313769 — Biomarker: FOXA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXA2; HNF3B; TCF3B
Study 36313769 — Biomarker: GLIS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GLIS3; ZNF515
Study 36313769 — Biomarker: WARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WARS1; IFI53; WARS; WRS
Study 36313769 — Biomarker: MTR mRNA
Type: Predictive Biomarker (PRD)
Genes: MTR
Study 36313769 — Biomarker: CDKAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKAL1
Study 34602386 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 33602945 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36364765 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 34428832 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36005837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36005837 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34047697 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33560411 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32809002 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32809002 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33704530 — Biomarker: MVD mRNA
Type: Predictive Biomarker (PRD)
Genes: MVD; MPD
Study 33704530 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 33704530 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 33039693 — Biomarker: Coagulation factor IIa
Type: Safety Biomarker (SAF)
Genes: F2
Study 33002704 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 36059000 — Biomarker: Chromodomain-helicase-DNA-binding protein 1
Type: Predictive Biomarker (PRD)
Genes: CHD1
Study 34363051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33582687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33239951 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34691212 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 32777383 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 34086194 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 34086194 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 32187464 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 36471427 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36245373 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 36245373 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35465733 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35465733 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 35465733 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35465733 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35465733 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 33264163 — Biomarker: SVOP mRNA
Type: Predictive Biomarker (PRD)
Genes: SVOP
Study 35685522 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32783912 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35472391 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33183969 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32645162 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34789340 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 36403976 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36403976 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 32596393 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32596393 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34044760 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 36002368 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32613718 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 32613718 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 33864832 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 32829105 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 35742443 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33086234 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32469184 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 35820835 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32805700 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35014061 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 34514890 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34514890 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34514890 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33755846 — Biomarker: GLA
Type: Predictive Biomarker (PRD)
Genes: GALA
Study 33746023 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34435469 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34435469 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32076569 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33368960 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32389013 — Biomarker: C1QA mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QA
Study 32389013 — Biomarker: C1QB mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QB
Study 32389013 — Biomarker: C1QC mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QC; C1QG
Study 32389013 — Biomarker: C1R mRNA
Type: Predictive Biomarker (PRD)
Genes: C1R
Study 32389013 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 32389013 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 32389013 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 32389013 — Biomarker: ITGAM mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGAM; CD11B; CR3A
Study 32389013 — Biomarker: ITGAX mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGAX; CD11C
Study 32164785 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32164785 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32164785 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35524006 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 32326806 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32591250 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34025637 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 36327047 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 33466131 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32111230 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 35023557 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35332040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32384727 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32384727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32635877 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32948867 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32948867 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32854834 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35458181 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 34387520 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 33941219 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 33941219 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34202464 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 35715946 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34424530 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36208853 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36208853 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 36208853 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32979074 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34082251 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34082251 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34297338 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 34810217 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34810217 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34810217 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33085058 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34261793 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34526397 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 33337698 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 33355713 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32217612 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34076752 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36194846 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33095682 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33780276 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 36660974 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32616309 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 32616309 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 32616309 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33308348 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35785139 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 35785139 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 33306634 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33306634 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 35791020 — Biomarker: CGAS mRNA
Type: Predictive Biomarker (PRD)
Genes: CGAS; C6orf150; MB21D1
Study 34545997 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34545997 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34545997 — Biomarker: TAFA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAFA5; FAM19A5; UNQ5208/PRO34524
Study 32481584 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32481584 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 32481584 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36078292 — Biomarker: CPOX mRNA
Type: Predictive Biomarker (PRD)
Genes: CPOX; CPO; CPX
Study 32552857 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 34422261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34589205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33377701 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 33291088 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34211322 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34211322 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)