AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 33609277 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 36422222 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34507573 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35864562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35864562 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35452273 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 33295083 — Biomarker: IL5RA mRNA
Type: Predictive Biomarker (PRD)
Genes: IL5RA; IL5R
Study 33295083 — Biomarker: ALOX15 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALOX15; LOG15
Study 33295083 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 33295083 — Biomarker: CLC mRNA
Type: Predictive Biomarker (PRD)
Genes: CLC; LGALS10; LGALS10A
Study 33295083 — Biomarker: PDE4D mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4D; DPDE3
Study 34954967 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34010611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35902939 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 35222585 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35222585 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 35837133 — Biomarker: ESD mRNA
Type: Predictive Biomarker (PRD)
Genes: ESD
Study 35051142 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 34488646 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34362344 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34362344 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 32271710 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34556722 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 34667023 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34667023 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34667023 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33642566 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 34052785 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33047449 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32497779 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33235112 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36418455 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33122892 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34516312 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 34516312 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33839205 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33839205 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33055122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33730454 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 35112416 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 34043029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34043029 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 35055603 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35656988 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34581911 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 32024944 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 32024944 — Biomarker: VKORC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 34348355 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 32493447 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 35766564 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35261113 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 35261113 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32592578 — Biomarker: FANCC
Type: Predictive Biomarker (PRD)
Genes: FAC; FA3
Study 33314365 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33389313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32652112 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 32652112 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 33217618 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33246482 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 34578981 — Biomarker: MAX mRNA
Type: Predictive Biomarker (PRD)
Genes: MAX; BHLHD4
Study 33413212 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35552287 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35552287 — Biomarker: BAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAG3; BIS
Study 34478863 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 33811051 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study 32425222 — Biomarker: CPZ mRNA
Type: Predictive Biomarker (PRD)
Genes: CPZ
Study 35232215 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35232215 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35418080 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32479794 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32479794 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34201795 — Biomarker: MC1R mRNA
Type: Predictive Biomarker (PRD)
Genes: MC1R; MSHR
Study 34454580 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 34454580 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35966092 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 32208960 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32208960 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 33498461 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 33789001 — Biomarker: Glycerol backbone
Type: Safety Biomarker (SAF)
Study 34951042 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 36372094 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 32376628 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32376628 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 33155295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32694412 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32988930 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study 33142117 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 35469509 — Biomarker: CPD mRNA
Type: Predictive Biomarker (PRD)
Genes: CPD
Study 33128722 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35505117 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 35710164 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 35710164 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35710164 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32932244 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 35131614 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33736819 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33712030 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 36441433 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32005283 — Biomarker: DST mRNA
Type: Predictive Biomarker (PRD)
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 35094695 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33915363 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33721439 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 35859328 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 35859328 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 616667359 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32053254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33946085 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32321350 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 35509490 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35509490 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 33647946 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 33647946 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33647946 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35278336 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 35278336 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35278336 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35077296 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36176927 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34170932 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33246428 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 35728369 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35728369 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 36302567 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 33809392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33809392 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 32933470 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35905418 — Biomarker: ADAM17 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAM17; CSVP; TACE
Study 32178701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32178701 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32178701 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 32178701 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32178701 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32178701 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 32178701 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 34830950 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 35432383 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33527809 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32232767 — Biomarker: miR-146b
Type: Safety Biomarker (SAF)
Genes: MIR146B
Study 34203476 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32381843 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32830463 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 32830463 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 34913186 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 34913186 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 32294652 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 32294652 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 32294652 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32294652 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34182967 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 36160152 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33111932 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 36035633 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35684022 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35684022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32350172 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32350172 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34635569 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 35167505 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33180001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34776874 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 34984851 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34632798 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 34632798 — Biomarker: TLR2
Type: Predictive Biomarker (PRD)
Genes: TIL4; CD282
Study 35674747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33504211 — Biomarker: Hydroxyphenylpyruvate dioxygenase
Type: Safety Biomarker (SAF)
Genes: HPD; PPD
Study 34339851 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33577373 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34645147 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 34645147 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34645147 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35731737 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 33789616 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34549356 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 34549356 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 35812820 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32546431 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 36412685 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34366306 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33119010 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 33119010 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34460132 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34460132 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35536547 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33215434 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 33483965 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 32432556 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34561890 — Biomarker: ABCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 32556865 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 32556865 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 32556865 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 32556865 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35642490 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33436709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35915198 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 33331923 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34049857 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 34696998 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 34368848 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35060417 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35643392 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32020725 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 34514678 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 35560363 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 35045098 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 34435273 — Biomarker: miR-142
Type: Safety Biomarker (SAF)
Genes: MIR142
Study 34435273 — Biomarker: miR-125b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32964458 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35314635 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35314635 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32594779 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34607519 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34607519 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32463456 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32463456 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 33761288 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33093616 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33093616 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32829060 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 32829060 — Biomarker: UCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCN3; SPC
Study 35258271 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36051936 — Biomarker: ITK mRNA
Type: Predictive Biomarker (PRD)
Genes: ITK; EMT; LYK
Study 32768001 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 35987076 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 35987076 — Biomarker: HOXA10 mRNA
Type: Predictive Biomarker (PRD)
Genes: HOXA10; HOX1H
Study 34261483 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33857750 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34202690 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34202690 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32967704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34083615 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 32897437 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34779837 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 36026840 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33514760 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT