AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT06765681 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06766591 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06767020 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study NCT04902443 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT06769295 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05513976 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT06108479 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT06769555 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT06769555 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study NCT05578976 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT06130254 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT05446090 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT06769893 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06657534 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04927299 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05178901 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06769022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06768255 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study NCT06380140 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06380140 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT06380140 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT05080829 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study NCT06344442 — Biomarker: Arginine vasopressin
Type: Predictive Biomarker (PRD)
Genes: AVP; ARVP; VP
Study NCT05814354 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06765031 — Biomarker: FST mRNA
Type: Predictive Biomarker (PRD)
Genes: FST
Study NCT05077813 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study NCT05077813 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT05077813 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study NCT00001128 — Biomarker: Interleukin 12
Type: Safety Biomarker (SAF)
Study NCT05030857 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT04715217 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT04715217 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT04460963 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study NCT04460963 — Biomarker: CD44 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT04460963 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT04460963 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study NCT04460963 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT06085066 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT06763783 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06763783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT06763783 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study NCT05735405 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04373122 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06333782 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05085002 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05085002 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05732129 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study NCT05335941 — Biomarker: MTAP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTAP; MSAP
Study NCT04893668 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04893668 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study NCT04893668 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05806671 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05806671 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT05806671 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05770531 — Biomarker: TACSTD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05770531 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study NCT05857228 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04854005 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT04854005 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06445582 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study NCT05751031 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study NCT06365307 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05512325 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05357183 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT04632199 — Biomarker: NTSR1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NTSR1; NTRR
Study NCT02723435 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT05184257 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05175885 — Biomarker: DCD mRNA
Type: Predictive Biomarker (PRD)
Genes: DCD; AIDD; DSEP
Study NCT06420466 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06593522 — Biomarker: MTAP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTAP; MSAP
Study NCT06447454 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study NCT06656312 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study NCT04902872 — Biomarker: CBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CBX1; CBX
Study NCT06585982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05786040 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04595084 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT05660135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05660135 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04972760 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT04972760 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT04972760 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study NCT05237388 — Biomarker: APOL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APOL1; APOL
Study NCT06071013 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05574036 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study NCT05290220 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06495541 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06030622 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study NCT05522075 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04619420 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05548933 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05548933 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT05548933 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study NCT05548933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05548933 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study NCT05548933 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05528133 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05528133 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT05426343 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05426343 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05094336 — Biomarker: MTAP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTAP; MSAP
Study NCT05374785 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT05374785 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study NCT05374785 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study NCT04903223 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT05498272 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04884971 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT04974307 — Biomarker: CLN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLN3; BTS
Study NCT05562141 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT06004661 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05339516 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT06488105 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06488105 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT00002379 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04372498 — Biomarker: KCNN4 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNN4; IK1; IKCA1; KCA4; SK4
Study NCT04676243 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study NCT05290467 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06394622 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04837677 — Biomarker: Induced myeloid leukemia cell differentiation protein Mcl-1
Type: Predictive Biomarker (PRD)
Genes: MCL1; BCL2L3
Study NCT05782387 — Biomarker: MCOLN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCOLN1; ML4; TRPML1; MSTP080
Study NCT06477328 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT06335147 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04304261 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT06041776 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05476796 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05771571 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT05771571 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06010875 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04723407 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05738980 — Biomarker: FRK mRNA
Type: Predictive Biomarker (PRD)
Genes: FRK; PTK5; RAK
Study NCT04015557 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study NCT04015557 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04850950 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT04412993 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study NCT05080231 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05954104 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04757337 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study NCT05651087 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05450406 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05450406 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06730932 — Biomarker: BTLA mRNA
Type: Predictive Biomarker (PRD)
Genes: BTLA
Study NCT05233579 — Biomarker: FMR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMR1
Study NCT05764070 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04853329 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT04973657 — Biomarker: AMN mRNA
Type: Predictive Biomarker (PRD)
Genes: AMN; UNQ513/PRO1028
Study NCT04973657 — Biomarker: ABCD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCD1; ALD
Study NCT06491667 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06491667 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study NCT06491667 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05752318 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study NCT06637540 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05522933 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06206395 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT06206395 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT05661201 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT05661201 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study NCT05543434 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05646550 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06356324 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04124367 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT04124367 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT05702944 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05171829 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT04782115 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05227573 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT04817540 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04817540 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study NCT05305183 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT06668831 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT06672250 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study NCT06667076 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06667076 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06512402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05770349 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study NCT05770349 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study NCT06147973 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05244980 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study NCT06023576 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05037331 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06346912 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06346912 — Biomarker: TNFSF13B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT05065021 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT06510335 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study NCT05027269 — Biomarker: DMPK mRNA
Type: Predictive Biomarker (PRD)
Genes: DMPK; DM1PK; MDPK
Study NCT05092061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05561075 — Biomarker: Nuclear factor erythroid 2-related factor 2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: NFE2L2; NRF2
Study NCT05561075 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study NCT04789057 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04789057 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04347655 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04885738 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study NCT06513598 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study NCT06054958 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06619483 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06150378 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study NCT04712383 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05333718 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT05744297 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04798079 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05124756 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT05935709 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study NCT05530512 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05152914 — Biomarker: Tripeptidyl-peptidase I
Type: Predictive Biomarker (PRD)
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT05164965 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT04767308 — Biomarker: CD5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD5; LEU1
Study NCT04132232 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study NCT06714656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06721507 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06721507 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06721507 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06721507 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT06721507 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06395519 — Biomarker: PARG mRNA
Type: Predictive Biomarker (PRD)
Genes: PARG
Study NCT06378710 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05164523 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05164523 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT05164523 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT04881526 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06075615 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06370247 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT05675605 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05643326 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06217185 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05750667 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study NCT05965570 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05998928 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study NCT05998928 — Biomarker: GPRC5D mRNA
Type: Predictive Biomarker (PRD)
Genes: GPRC5D