AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 36099091 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36099091 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32472001 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32472001 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 33532956 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36036107 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 32423457 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36070590 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33390654 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36216309 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 36216309 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 36216309 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 33533820 — Biomarker: ASPSCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 36290823 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34382434 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33038338 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33038338 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 33038338 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 33038338 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33038338 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33038338 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 32925908 — Biomarker: MCAT mRNA
Type: Predictive Biomarker (PRD)
Genes: MCAT; MT
Study 34363558 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 32164886 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35297744 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 35063242 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 32622610 — Biomarker: HTR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR4
Study 32622610 — Biomarker: SLC4A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A4; NBC; NBC1; NBCE1
Study 32622610 — Biomarker: HTR2B mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2B
Study 33788296 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 35606010 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35308141 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 35308141 — Biomarker: Urinary microalbumin
Type: Safety Biomarker (SAF)
Study 35761219 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32183736 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32183736 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 33514329 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33514329 — Biomarker: IL1RN mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RN; IL1F3; IL1RA
Study 32018062 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 36235569 — Biomarker: BSG mRNA
Type: Predictive Biomarker (PRD)
Genes: BSG; UNQ6505/PRO21383
Study 35512620 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 32802833 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 36335191 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 32144319 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32144319 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32144319 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36173415 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35862120 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35726351 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34195988 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 34195988 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 32545056 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36102943 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 33044684 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 33044684 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 33596883 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35738494 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 35738494 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 35738494 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 34403608 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33704351 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33554371 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32513231 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33151364 — Biomarker: CORIN mRNA
Type: Predictive Biomarker (PRD)
Genes: CORIN; CRN; TMPRSS10
Study 34961793 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 33234846 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36388925 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36388925 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34961418 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35258533 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32301053 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32314939 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 36141488 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34595804 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33189900 — Biomarker: TRPV4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV4; VRL2; VROAC
Study 32197373 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32197373 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34989804 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35240678 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34674750 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33506798 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32529811 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 33206786 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33206786 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32520900 — Biomarker: BCHE
Type: Safety Biomarker (SAF)
Genes: E1
Study 33783488 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36271193 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 36271193 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32681996 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33385417 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 33385417 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 33385417 — Biomarker: CHAF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: CHAF1A; CAF; CAF1P150
Study 35667065 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35661487 — Biomarker: POSTN mRNA
Type: Predictive Biomarker (PRD)
Genes: POSTN; OSF2
Study 35661487 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 616774602 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 35648053 — Biomarker: TNNT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNNT1; TNT
Study 35648053 — Biomarker: AWAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 34264439 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 34264439 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 34264439 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 34264439 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 36052414 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 36052414 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study 33302270 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35253582 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 35101086 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34579146 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33119156 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35241003 — Biomarker: ADORA2A
Type: Safety Biomarker (SAF)
Genes: RDC8
Study 36200674 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 32407216 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33983512 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 33983512 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 32164439 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 32679568 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35384630 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 32398304 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 34865278 — Biomarker: Major prion protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRNP; ALTPRP; PRIP; PRP
Study 33804738 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33804738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34321278 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34321278 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 34990776 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32707342 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 32556481 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 36253765 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 36404171 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32059710 — Biomarker: NRF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRF1
Study 36079806 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 33814247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34124840 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34258913 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 34258913 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34284351 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 36132545 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32734461 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 33455117 — Biomarker: WWOX mRNA
Type: Predictive Biomarker (PRD)
Genes: WWOX; FOR; SDR41C1; WOX1
Study 32363972 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35728875 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35728875 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35728875 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35728875 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 35728875 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36418750 — Biomarker: miR-142
Type: Safety Biomarker (SAF)
Genes: MIR142
Study 35940738 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32712103 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32892184 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 35711602 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35657028 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 35657028 — Biomarker: NELFCD mRNA
Type: Predictive Biomarker (PRD)
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 32042073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32398091 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36271264 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33568343 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 35335885 — Biomarker: GEM mRNA
Type: Predictive Biomarker (PRD)
Genes: GEM; KIR
Study 35335885 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 32410705 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32503662 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32503662 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33316649 — Biomarker: L1CAM mRNA
Type: Predictive Biomarker (PRD)
Genes: L1CAM; CAML1; MIC5
Study 33316649 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 33316649 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33022918 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33022918 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34216468 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32009491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35449818 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35449818 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32022434 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 35501846 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35501846 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35645070 — Biomarker: DSP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSP
Study 32608989 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 32868138 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 32791048 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 32456512 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33471240 — Biomarker: Total kidney volume
Type: Surrogate Endpoint (SUR)
Study 35997713 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 35256446 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32443139 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 33974725 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33974725 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32529467 — Biomarker: APEX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 33278562 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 34024811 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 33232804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32496365 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32496365 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34752723 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33969434 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 33969434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35751895 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36011639 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 32447858 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 32447858 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 34528132 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 33185325 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 35323106 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 36004709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34774485 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35016629 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 35016629 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35016629 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 33132345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34391532 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34391532 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32209963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35660501 — Biomarker: SQSTM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SQSTM1; ORCA; OSIL
Study 35660501 — Biomarker: LAMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMP2
Study 33196574 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32147362 — Biomarker: MAP3K5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 36246987 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 36246987 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 36334013 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36414931 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 33770195 — Biomarker: SLC2A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC2A4; GLUT4
Study 33770195 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 33583066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35325622 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 35338353 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 35845740 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 32360666 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 35379563 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33570647 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 33955229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35501676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32249637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32249637 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 32249637 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34360036 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33819336 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36149935 — Biomarker: miR-1
Type: Safety Biomarker (SAF)
Study 36149935 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 34156521 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 34787258 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32388647 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 33485731 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33485731 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33485731 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33485731 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 33220095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36474274 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35435086 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE