AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 39011963 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39012221 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39012233 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 39012250 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 39012630 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39012717 — Biomarker: COL1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A1
Study 39012717 — Biomarker: COL1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL1A2
Study 39012717 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39012717 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39012843 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 39012946 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39013470 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39013654 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 39013870 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 39014136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39014463 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 39014551 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 39015176 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 39015189 — Biomarker: F2R mRNA
Type: Predictive Biomarker (PRD)
Genes: F2R; CF2R; PAR1; TR
Study 39015350 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39016010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39016053 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 39016381 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 39017806 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 39018038 — Biomarker: IL13RA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL13RA1; IL13R; IL13RA
Study 39018053 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39018053 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39018053 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39018531 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39019119 — Biomarker: IGFBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP4; IBP4
Study 39019119 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39019119 — Biomarker: Vitamin K-dependent protein S
Type: Safety Biomarker (SAF)
Genes: PROS1; PROS
Study 39019150 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 39019496 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39019657 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39019875 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 39019979 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 39019979 — Biomarker: CYP17A1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CYP17A1; CYP17; S17AH
Study 39019979 — Biomarker: SRD5A2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SRD5A2
Study 39020305 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 39020446 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 39020503 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 39020518 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 39021216 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 39022168 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 39022429 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 39022796 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39022889 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 39023142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39023253 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39023253 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39023287 — Biomarker: KLRC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC1; NKG2A
Study 39023418 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 39023418 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39023568 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study 39023568 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39023568 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 39023568 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 39023568 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 39023568 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 39023880 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 39024777 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39025066 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39025092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39025264 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 39025264 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 39025948 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39025948 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 39025948 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 39025948 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39026154 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39026154 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39026154 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 39026154 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39026552 — Biomarker: GCA mRNA
Type: Predictive Biomarker (PRD)
Genes: GCA; GCL
Study 39027419 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 39027664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39028412 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 39028763 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39028916 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39028916 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 39028923 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39028931 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 39028931 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 39029241 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 39029295 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 39029568 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39029876 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 39029876 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 39030063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39030183 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 39030183 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 39031189 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 39031276 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39031276 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39031356 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 39031356 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 39031356 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 39031356 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 39033240 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39033369 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39033692 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 39033692 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 39033767 — Biomarker: Chromosome 5q
Type: Predictive Biomarker (PRD)
Study 39033770 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 39033774 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 39033774 — Biomarker: DNA mismatch repair protein MSH2
Type: Predictive Biomarker (PRD)
Genes: MSH2
Study 39033774 — Biomarker: EPCAM mRNA
Type: Predictive Biomarker (PRD)
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study 39033924 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 39033994 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39034414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39034493 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 39035044 — Biomarker: NEO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEO1; IGDCC2; NGN
Study 39035044 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 39035614 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39035725 — Biomarker: Thymidylate synthase 
Type: Predictive Biomarker (PRD)
Genes: TYMS; TS; OK/SW-cl.29
Study 39035774 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39036069 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39037824 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 39037964 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39037964 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 39037964 — Biomarker: CD69 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD69; CLEC2C
Study 39037964 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39038251 — Biomarker: KLK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLK2
Study 39038251 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 39038404 — Biomarker: REM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: REM1; GES; REM
Study 39038917 — Biomarker: MAGEA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGEA1; MAGE1; MAGE1A
Study 39038917 — Biomarker: Human leucocyte antigen
Type: Safety Biomarker (SAF)
Study 39039086 — Biomarker: JUN mRNA
Type: Predictive Biomarker (PRD)
Genes: JUN
Study 39039086 — Biomarker: ZAP70 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZAP70; SRK
Study 39039086 — Biomarker: EPHB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO5
Study 39039449 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 39039509 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 39039516 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39039609 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39041200 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 39041200 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 39041351 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 39041351 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39041411 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 39042017 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 39042292 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39042613 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 39042613 — Biomarker: NFKBIA mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 39042613 — Biomarker: NFKBIZ mRNA
Type: Predictive Biomarker (PRD)
Genes: NFKBIZ; IKBZ; INAP; MAIL
Study 39042613 — Biomarker: FOSL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOSL2; FRA2
Study 39042613 — Biomarker: JDP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JDP2
Study 39042613 — Biomarker: PIK3R1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3R1; GRB1
Study 39042613 — Biomarker: CLEC7A mRNA
Type: Predictive Biomarker (PRD)
Genes: CLEC7A; BGR; CLECSF12; DECTIN1; UNQ539/PRO1082
Study 39042613 — Biomarker: DUSP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: DUSP6; MKP3; PYST1
Study 39042613 — Biomarker: NCF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NCF2; NOXA2; P67PHOX
Study 39042613 — Biomarker: PLCB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLCB1; KIAA0581
Study 39042770 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 39042892 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39043009 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39043348 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39043397 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39043682 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39043682 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 39043682 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 39043871 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 39043915 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39044019 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 39044659 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 39044797 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 39044861 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 39045200 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39045484 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39045544 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 39045758 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39045758 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 39045758 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39046150 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39046616 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39046616 — Biomarker: GP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GP2
Study 39046616 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39046647 — Biomarker: ADCY10 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADCY10; SAC
Study 39046695 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 39046695 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 39046727 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 39046727 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 39046783 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 39046783 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 39046783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39046783 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 39046783 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 39047180 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 39047219 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39047288 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 39048547 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39048549 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39048549 — Biomarker: MIF mRNA
Type: Predictive Biomarker (PRD)
Genes: MIF; GLIF; MMIF
Study 39048549 — Biomarker: ELANE mRNA
Type: Predictive Biomarker (PRD)
Genes: ELANE; ELA2
Study 39048549 — Biomarker: DEFA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DEFA4; DEF4
Study 39048549 — Biomarker: OLFM4 mRNA
Type: Predictive Biomarker (PRD)
Genes: OLFM4; GW112; UNQ362/PRO698
Study 39049042 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 39049073 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 39049073 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39049092 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 39049121 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 39049803 — Biomarker: Ribonucleoside-diphosphate reductase large subunit
Type: Predictive Biomarker (PRD)
Genes: RRM1; RR1
Study 39049803 — Biomarker: RRM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RRM2; RR2
Study 39049828 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 39050403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39050802 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 39050802 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 39052241 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 39052242 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 39052330 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39052718 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39052726 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39053010 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 39053611 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 39053611 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 39053948 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39053954 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 39053957 — Biomarker: SLC25A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 39054420 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 39054460 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 39054462 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 39054476 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39054479 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 39054485 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 39054485 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39054491 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 39054765 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 39054765 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 39055379 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 39055495 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39055703 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39055703 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39055703 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 39056160 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39056338 — Biomarker: RXFP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RXFP1; LGR7
Study 39058972 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)