AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35812198 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 35995769 — Biomarker: RARA mRNA
Type: Predictive Biomarker (PRD)
Genes: RARA; NR1B1
Study 35995769 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 35995769 — Biomarker: AADAC mRNA
Type: Predictive Biomarker (PRD)
Genes: AADAC; DAC
Study 35995769 — Biomarker: HIC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HIC1; ZBTB29
Study 35995769 — Biomarker: CYP26A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP26A1; CYP26; P450RAI1
Study 35995769 — Biomarker: GBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: GBP4
Study 35995769 — Biomarker: LYZ mRNA
Type: Predictive Biomarker (PRD)
Genes: LYZ; LZM
Study 32940404 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32940404 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32940404 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32917495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32510737 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35172859 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32776101 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 34416469 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34022474 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34022474 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 35067237 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34014249 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34014249 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34014249 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35329366 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35617826 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32470703 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 32470703 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32333510 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 35018724 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 35331534 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 35331534 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36383882 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 35405335 — Biomarker: CTLA4
Type: Predictive Biomarker (PRD)
Genes: CD152; CD; GSE; CTLA-4
Study 36112790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34602038 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 32065946 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 32065946 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 32970104 — Biomarker: CSF3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CSF3; C17orf33; GCSF
Study 34718548 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 32394652 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 32394652 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 33410359 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 36320214 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34711947 — Biomarker: ABCG2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 33094728 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33094728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33094728 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33094728 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33094728 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35113605 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 33984786 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32357081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33031169 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32075842 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33210382 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 32329438 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 32329438 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32329438 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32329438 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35970940 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 35229621 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32176107 — Biomarker: ELP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELP1; IKAP; IKBKAP
Study 32176107 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33332234 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 36064876 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 36064876 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 33800392 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35760812 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 36141561 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34351414 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32140428 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33755863 — Biomarker: CLDN18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN18; UNQ778/PRO1572
Study 33711380 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 33711380 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33711380 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32757523 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34525247 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35697571 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 35816621 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 32987892 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32987892 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35989346 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 34125135 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 32242145 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33881710 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35669738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33896388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34009291 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 33589320 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 33589320 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 32761844 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32761844 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35481935 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32352320 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35373340 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32866624 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study 32866624 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32866624 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32992785 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 36197287 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 32291360 — Biomarker: SCT mRNA
Type: Predictive Biomarker (PRD)
Genes: SCT
Study 33600092 — Biomarker: GK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GK2; GKP2; GKTA
Study 33548159 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 34031262 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 33026143 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33964325 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 34561086 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32294560 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 36371994 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33245905 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35980383 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 32997825 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 32997825 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35347399 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34070866 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 36012890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33420287 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 32006484 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 33819238 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33819238 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34029521 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34969649 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 35772219 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35422427 — Biomarker: CCL18 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 35422427 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 32114729 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 34089483 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33638801 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 34883305 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32990454 — Biomarker: DPT mRNA
Type: Predictive Biomarker (PRD)
Genes: DPT
Study 33316426 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 33777424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34987499 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32003737 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32003737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32003737 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35580621 — Biomarker: TAT mRNA
Type: Predictive Biomarker (PRD)
Genes: TAT
Study 34879449 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 33023946 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33023946 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33023946 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 33023946 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 33418231 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 32805740 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32707001 — Biomarker: ITGA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGA5; FNRA
Study 32707001 — Biomarker: CD93 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD93; C1QR1; MXRA4
Study 32707001 — Biomarker: miR-92a-3p
Type: Monitoring Biomarker (MOI)
Study 35263681 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 33441157 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33142016 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35710395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33213400 — Biomarker: FHL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FHL5; ACT
Study 34018342 — Biomarker: Mitochondrial frataxin
Type: Monitoring Biomarker (MOI)
Genes: FXN; FRDA; X25
Study 34090495 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34704877 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33887429 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 33887429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33573681 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33573681 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 32661522 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32591594 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 32618244 — Biomarker: DDT mRNA
Type: Predictive Biomarker (PRD)
Genes: DDT
Study 33067295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33208263 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 33208263 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 35720377 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35720377 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32645163 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32891918 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 33028054 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 36167610 — Biomarker: Metalloproteinase inhibitor 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TIMP1; CLGI; TIMP
Study 36167610 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 36167610 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 34634368 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32053110 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 32053110 — Biomarker: GPR55 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR55
Study 32053110 — Biomarker: Solute carrier family 29 member 1
Type: Predictive Biomarker (PRD)
Genes: SLC29A1; ENT1
Study 33001140 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 35347429 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32646462 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 35395080 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 35395080 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33979451 — Biomarker: Cyclin-dependent kinase-like 5
Type: Predictive Biomarker (PRD)
Genes: CDKL5; STK9
Study 34911462 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34911462 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 33768772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34941131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33951265 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34861374 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 35228754 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32696816 — Biomarker: SACS mRNA
Type: Predictive Biomarker (PRD)
Genes: SACS; KIAA0730
Study 33225554 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 33225554 — Biomarker: TTN mRNA
Type: Predictive Biomarker (PRD)
Genes: TTN
Study 33225554 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34959836 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 33415859 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34762375 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 33711081 — Biomarker: EEF1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EEF1A2; EEF1AL; STN
Study 32899117 — Biomarker: BMAL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 33858221 — Biomarker: CGB8 mRNA
Type: Predictive Biomarker (PRD)
Genes: CGB3; CGB; CGB5; CGB8
Study 33372185 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 35170727 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33658261 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35361446 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34555421 — Biomarker: LTA mRNA
Type: Predictive Biomarker (PRD)
Genes: LTA; TNFB; TNFSF1
Study 32548283 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 33941192 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35003321 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32037653 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 35486014 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32682793 — Biomarker: RB1
Type: Predictive Biomarker (PRD)
Genes: RB; PPP1R130
Study 32399662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32580813 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32770262 — Biomarker: TRPV2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV2; VRL
Study 36323488 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 32909326 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32909326 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33684370 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 35655124 — Biomarker: SOD3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SOD3
Study 35655124 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33761061 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33864070 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33864070 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 34167567 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 33388426 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33388426 — Biomarker: Histone acetylation
Type: Pharmacodynamic Biomarker (PDY)
Study 32389610 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 35581440 — Biomarker: AIF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AIF1; G1; IBA1
Study 32014035 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32730174 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34192430 — Biomarker: Tissue transglutaminase
Type: Monitoring Biomarker (MOI)
Genes: TGM2