AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32759236 — Biomarker: NOTCH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTCH1; TAN1
Study 32759236 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33457425 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32905642 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 34619106 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33020051 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34994685 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35759826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34386597 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34372849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32028804 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34716085 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 35483093 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32505378 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35385395 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35365139 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33756250 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 33756250 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33756250 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 32620917 — Biomarker: MLH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MLH1; COCA2
Study 32620917 — Biomarker: RNF43 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNF43
Study 32620917 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 32620917 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 32620917 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 32620917 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32620917 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 32620917 — Biomarker: CTNNB1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 32620917 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 32620917 — Biomarker: TGFBR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TGFBR2
Study 32620917 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 36174744 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 35175317 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 33069714 — Biomarker: DNMT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT1; AIM; CXXC9; DNMT
Study 33069714 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 33069714 — Biomarker: DNMT3B mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3B
Study 33069714 — Biomarker: TET1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET1; CXXC6; KIAA1676; LCX
Study 33069714 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 33069714 — Biomarker: TET3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET3; KIAA0401
Study 35708706 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35708706 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32228238 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35437929 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32910197 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35430680 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32688143 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 33358790 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33358790 — Biomarker: CCS mRNA
Type: Predictive Biomarker (PRD)
Genes: CCS
Study 32942924 — Biomarker: HFE mRNA
Type: Predictive Biomarker (PRD)
Genes: HFE; HLAH
Study 33121228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35224034 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35224034 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34235608 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 32186106 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 36494329 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 34065454 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35300814 — Biomarker: LPAR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LPAR4; GPR23; LPA4; P2RY9
Study 35300814 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33125080 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 33125080 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 33125080 — Biomarker: IGFBP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP4; IBP4
Study 33125080 — Biomarker: IGFBP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP6; IBP6
Study 33125080 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 33125080 — Biomarker: IGFBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP1; IBP1
Study 33125080 — Biomarker: IGFBP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP3; IBP3
Study 35337143 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35337143 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33411684 — Biomarker: Ataxin-2
Type: Pharmacodynamic Biomarker (PDY)
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 32441643 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32690008 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32569126 — Biomarker: HTR2A mRNA
Type: Predictive Biomarker (PRD)
Genes: HTR2A; HTR2
Study 32569126 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 33379851 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33379851 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 33379851 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33151286 — Biomarker: Indoleamine 2,3-dioxygenase 1
Type: Predictive Biomarker (PRD)
Genes: IDO1; IDO; INDO
Study 33151286 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35574743 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32065000 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 32065000 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 35400584 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 35400584 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 35400584 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 36270309 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 32016466 — Biomarker: SLC2A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC2A1; GLUT1
Study 35791276 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32741099 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34446053 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 34446053 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 36196729 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32556602 — Biomarker: WEE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WEE1
Study 32155622 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 32155622 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 35868849 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 35868849 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 35868849 — Biomarker: PALB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PALB2; FANCN
Study 34496743 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study 32518098 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 32518098 — Biomarker: MCTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MCTS1; MCT1
Study 32518098 — Biomarker: SLC16A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC16A4; MCT4; MCT5
Study 32260470 — Biomarker: ABCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA1; ABC1; CERP
Study 32423239 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 32915523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36346079 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 32729802 — Biomarker: Cytochrome c
Type: Safety Biomarker (SAF)
Study 33030064 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32988525 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32988525 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 32988525 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34604936 — Biomarker: PISD mRNA
Type: Predictive Biomarker (PRD)
Genes: PISD
Study 32047951 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35324270 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 35878838 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34706567 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 33054121 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 33491438 — Biomarker: ACKR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACKR1; DARC; FY; GPD
Study 35277011 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32147060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35562713 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 34803872 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 32967430 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 36456969 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34237250 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33403890 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33512755 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 35504446 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33734030 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 35429480 — Biomarker: Cyclin-dependent kinase-like 5
Type: Predictive Biomarker (PRD)
Genes: CDKL5; STK9
Study 33998590 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 32800391 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 35258786 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33934542 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33422431 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35446628 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32792359 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32792359 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32792359 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 35691258 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33722477 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 35277461 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 32840311 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 34252252 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34636852 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33432367 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32686744 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 34334142 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34334142 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34865009 — Biomarker: MAG mRNA
Type: Predictive Biomarker (PRD)
Genes: MAG; GMA
Study 35402989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34117867 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 34117867 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 33480087 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 33480087 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 33480087 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 33480087 — Biomarker: PAX5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX5
Study 33480087 — Biomarker: CD68 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD68
Study 33480087 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 33317479 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 33482902 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34006508 — Biomarker: CNGA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNGA3; CNCG3
Study 33040631 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33040631 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 32170867 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 36075246 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 33283485 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 35559241 — Biomarker: PCSK7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 34258270 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34253679 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 34253679 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 34253679 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 35733519 — Biomarker: FBXO8 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 33775313 — Biomarker: ITGAM mRNA
Type: Predictive Biomarker (PRD)
Genes: ITGAM; CD11B; CR3A
Study 33049412 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 35586118 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34345377 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 35115825 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32989795 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 33407788 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 35370460 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34225535 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33277982 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33277982 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35703882 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35703882 — Biomarker: CPE mRNA
Type: Predictive Biomarker (PRD)
Genes: CPE
Study 33854050 — Biomarker: SLC10A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC10A3; DXS253E; P3
Study 33434094 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 33888367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35771961 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 33040810 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33040810 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32011301 — Biomarker: TPO mRNA
Type: Predictive Biomarker (PRD)
Genes: TPO
Study 32011301 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 32011301 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 32012411 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34971040 — Biomarker: AMIGO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMIGO1; ALI2; AMIGO; KIAA1163
Study 32266572 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 33565237 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34332584 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34332584 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33547487 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35775723 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 33043353 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34256031 — Biomarker: TSLP mRNA
Type: Predictive Biomarker (PRD)
Genes: TSLP
Study 34256031 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32359153 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35953719 — Biomarker: Cholesteryl ester transfer protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: CETP
Study 35953719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35953719 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32051386 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35114340 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 35114340 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35114340 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32380449 — Biomarker: SEMG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMG1; SEMG
Study 35524415 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34463434 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 35202553 — Biomarker: SULT1A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SULT1A3; STM
Study 33592607 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 35490599 — Biomarker: FADS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FADS1; FADSD5
Study 33455792 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33567127 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32150085 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33622079 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 35614518 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 35788622 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35085503 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 35085503 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34325186 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34598813 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 32119714 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 35347281 — Biomarker: COL7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL7A1
Study 35347281 — Biomarker: Complement C7
Type: Monitoring Biomarker (MOI)
Genes: C7
Study 33508990 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34476629 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 33975039 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33975039 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32004709 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33958657 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35217575 — Biomarker: LAG3 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAG3; FDC
Study 34518266 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32940187 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32940187 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 33683019 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT