AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 39525887 — Biomarker: GCNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GCNT2; GCNT5; II; NACGT1
Study 39526078 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 39526855 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39526855 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 39527056 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39527097 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39527097 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 39527097 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 39527236 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 39527236 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 39528489 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 39528916 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 39529054 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 39529054 — Biomarker: PRX mRNA
Type: Predictive Biomarker (PRD)
Genes: PRX; KIAA1620
Study 39529169 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 39530130 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 39530262 — Biomarker: High-frequency oscillations
Type: Pharmacodynamic Biomarker (PDY)
Study 39530558 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 39530558 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 39530627 — Biomarker: DLL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLL3
Study 39531369 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 39531903 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 39532185 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 39532238 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 39532835 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 39532861 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39533015 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 39533015 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 39533186 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39533194 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39533204 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 39533349 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39533349 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 39533412 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 39534481 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39534593 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 39534856 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 39535306 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 39536433 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39536433 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39536455 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39536455 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39536691 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 39536847 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 39536847 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39537191 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 39537385 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 39537648 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39538139 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39538139 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 39540799 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 39541094 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39541169 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 39541169 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39541202 — Biomarker: KMT2D mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2D; ALR; MLL2; MLL4
Study 39541202 — Biomarker: COL4A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL4A4
Study 39541202 — Biomarker: CTNNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTNNA2; CAPR
Study 39541202 — Biomarker: SCN4A mRNA
Type: Predictive Biomarker (PRD)
Genes: SCN4A
Study 39541377 — Biomarker: SDHA mRNA
Type: Predictive Biomarker (PRD)
Genes: SDHA; SDH2; SDHF
Study 39541377 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 39541377 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 39541377 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study 39541993 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 39542642 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 39542655 — Biomarker: CKM mRNA
Type: Predictive Biomarker (PRD)
Genes: CKM; CKMM
Study 39542655 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 39542655 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 39543304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39543527 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 39543578 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 39544897 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 39544899 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 39545451 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 39546040 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39546129 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 39546748 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 39546748 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 39546931 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 39546931 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39546957 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39547230 — Biomarker: ARSB mRNA
Type: Predictive Biomarker (PRD)
Genes: ARSB
Study 39547694 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39548016 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39548016 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39548306 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 39548306 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 39548414 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 39548414 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39548423 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39548423 — Biomarker: FASN mRNA
Type: Predictive Biomarker (PRD)
Genes: FASN; FAS
Study 39548560 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 39549554 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39549554 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 39549678 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 39549678 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 39549719 — Biomarker: POMC mRNA
Type: Predictive Biomarker (PRD)
Genes: POMC
Study 39549719 — Biomarker: PCSK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK1; NEC1
Study 39549719 — Biomarker: LEPROT mRNA
Type: Predictive Biomarker (PRD)
Genes: LEPROT; LEPR; OBR
Study 39550530 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39550716 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 39551007 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 39551040 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39551040 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39551040 — Biomarker: LRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRIT1; LRRC21; PAL
Study 39551093 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 39551167 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39551469 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 39551469 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 39551469 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 39551470 — Biomarker: SERPINA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 39551600 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 39551600 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 39551791 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39551891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39551891 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39554793 — Biomarker: ALDH1A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 39554793 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 39555818 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 39555823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39555827 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39555828 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 39555828 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 39556016 — Biomarker: LAMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMP2
Study 39556016 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 39556016 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 39556389 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 39556768 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39557058 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39560075 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 39560398 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 39561184 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 39561225 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 39561281 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study 39561359 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 39561689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39561689 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 39562048 — Biomarker: miR-106b
Type: Predictive Biomarker (PRD)
Genes: MIR106B
Study 39562048 — Biomarker: miR-146a
Type: Safety Biomarker (SAF)
Genes: MIR146A
Study 39562048 — Biomarker: miR-15a
Type: Safety Biomarker (SAF)
Genes: MIR15A
Study 39562048 — Biomarker: miR-18a
Type: Safety Biomarker (SAF)
Genes: MIR18A
Study 39562048 — Biomarker: miR-21
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR21
Study 39562048 — Biomarker: miR-93
Type: Predictive Biomarker (PRD)
Genes: MIR93
Study 39562502 — Biomarker: FANCA mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCA; FAA; FACA; FANCH
Study 39562502 — Biomarker: FANCD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCD2; FACD
Study 39563035 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39563035 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 39563094 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 39563102 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 39563248 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 39563319 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 39563886 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 39563886 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 39565276 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 39565449 — Biomarker: Lactotransferrin
Type: Safety Biomarker (SAF)
Genes: LTF; GIG12; LF
Study 39565495 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39565495 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 39565905 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 39566404 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 39566467 — Biomarker: TP63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study 39566600 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 39567210 — Biomarker: LILRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LILRB2; ILT4; LIR2; MIR10
Study 39567211 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 39568009 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 39568724 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 39568724 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 39568724 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 39568724 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 39569196 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 39570031 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 39570213 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39570398 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39570545 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39570590 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 39570620 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 39571113 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39571171 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 39571171 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39571171 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39571342 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 39571744 — Biomarker: GAST mRNA
Type: Predictive Biomarker (PRD)
Genes: GAST; GAS
Study 39572264 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39572264 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 39572264 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 39572264 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 39572264 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 39572264 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 39572681 — Biomarker: ANXA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D
Study 39572739 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 39572763 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 39572763 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 39574155 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 39574505 — Biomarker: MXD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MXD1; MAD
Study 39574523 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 39575028 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 39575188 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 39575188 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 39575565 — Biomarker: CD27 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD27; TNFRSF7
Study 39575565 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 39575727 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39575854 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39576675 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39576683 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39576798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39577214 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39577214 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 39577511 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 39577691 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 39577708 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 39577867 — Biomarker: NR2E1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR2E1; TLX
Study 39577975 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39578309 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 39578347 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 39578778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 39578778 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 39578819 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 39578819 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 39579274 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 39580145 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 39580145 — Biomarker: Angiopoietin-2
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ANGPT2
Study 39580437 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 39580468 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39580468 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 39580601 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 39580622 — Biomarker: RARB mRNA
Type: Predictive Biomarker (PRD)
Genes: RARB; HAP; NR1B2
Study 39580622 — Biomarker: LRP1B mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1B; LRPDIT
Study 39580793 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 39581180 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 39581330 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 39581380 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 39581380 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 39581887 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 39581892 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 39581892 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39581892 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 39582029 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 39582544 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 39582666 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 39582898 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39583653 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 39583952 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 39583952 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 39583953 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 39583953 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 39584380 — Biomarker: C12orf57 mRNA
Type: Predictive Biomarker (PRD)
Genes: C12orf57; C10
Study 39584464 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)