AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32553077 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33822067 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 32873667 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34265044 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34265044 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33022421 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 33302661 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33400845 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34337913 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32119803 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36474395 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32463566 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 32463566 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 32463566 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32681239 — Biomarker: ROBO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROBO2; KIAA1568
Study 32681239 — Biomarker: CTNND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CTNND2; NPRAP
Study 32681239 — Biomarker: SGCZ mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCZ
Study 32681239 — Biomarker: CNTN5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTN5
Study 32681239 — Biomarker: BAIAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BAIAP2
Study 35101369 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 32648924 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34224251 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 32029355 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 36351326 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 32792679 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 32792679 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32792679 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34375387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33191846 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 616117430 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 35748715 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 35248121 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 35248121 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33615722 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36356514 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 34472754 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 34472754 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34472754 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 34472754 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34472754 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 34472754 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 32480076 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 33664161 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 33664161 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 33052760 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35344476 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 35344476 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33417663 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32379280 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 32379280 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32379280 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 34278827 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 35932065 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 35932065 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34267689 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 35301577 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 35301577 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 34341423 — Biomarker: MYB mRNA
Type: Predictive Biomarker (PRD)
Genes: MYB
Study 34341423 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 34341423 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 32660725 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33076762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32965715 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33206263 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33710154 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 36002594 — Biomarker: EMD mRNA
Type: Predictive Biomarker (PRD)
Genes: EMD; EDMD; STA
Study 35686365 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32091548 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32498561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33009241 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33775867 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 33775867 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33109240 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34426442 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34871204 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 33131126 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35763249 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32267032 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 32267032 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 32267032 — Biomarker: SLC9A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC9A1; APNH1; NHE1
Study 32779001 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 32779001 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35569763 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 33113088 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35564330 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study 34639313 — Biomarker: VAPA mRNA
Type: Predictive Biomarker (PRD)
Genes: VAPA; VAP33
Study 34639313 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32456236 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35672660 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34292493 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 35302207 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33580595 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 33580595 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 33580595 — Biomarker: Peroxisome proliferator-activated receptor alpha
Type: Safety Biomarker (SAF)
Genes: PPARA
Study 32167393 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 32167393 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 32167393 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 35064330 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32353342 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32353342 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32353342 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32661681 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 32661681 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32661681 — Biomarker: NPSR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPSR1; GPR154; GPRA; PGR14
Study 32661681 — Biomarker: Nicotinamide phosphoribosyltransferase
Type: Safety Biomarker (SAF)
Genes: NAMPT; PBEF; PBEF1
Study 34167597 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34167597 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32017817 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 32017817 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 35578268 — Biomarker: PRKAR1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKAR1B
Study 35578268 — Biomarker: PDE4C mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE4C; DPDE1
Study 35098782 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35098782 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 32732354 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 32732354 — Biomarker: CALR mRNA
Type: Predictive Biomarker (PRD)
Genes: CALR; CRTC
Study 32732354 — Biomarker: MPL mRNA
Type: Predictive Biomarker (PRD)
Genes: MPL; TPOR
Study 32732354 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 32732354 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 32732354 — Biomarker: EZH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EZH2; KMT6
Study 32732354 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 32732354 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 32732354 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32732354 — Biomarker: U2AF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study 36153457 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 36153457 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 33908285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35983524 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35983524 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35362717 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35714276 — Biomarker: SPR mRNA
Type: Predictive Biomarker (PRD)
Genes: SPR
Study 32149879 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34370327 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 35703114 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 36227238 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34702332 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 32907352 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35648204 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 35588050 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35588050 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35588050 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35588050 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 35588050 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 32223963 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32223963 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 32223963 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 32223963 — Biomarker: IER3 mRNA
Type: Predictive Biomarker (PRD)
Genes: IER3; DIF2; IEX1; PRG1
Study 32223963 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 32646561 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32646561 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34860705 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34860705 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34860705 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36108849 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36108849 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 36108849 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33928827 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34139220 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35196580 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35715806 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32333641 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 32500486 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 32500486 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32500486 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32500486 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 35726289 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35726289 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35726289 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 35726289 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32198342 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36314226 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32521736 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 32521736 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 35025152 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 35452108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33455786 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33455786 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34446480 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 36467457 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35273566 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35273566 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36182638 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33250038 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 35164833 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34676808 — Biomarker: SERPINB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINB3; SCCA; SCCA1
Study 34676808 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 34676808 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34676808 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 36120805 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 34226144 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32542906 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 32580282 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 36099069 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32910141 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 35648299 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34043229 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 33420472 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33420472 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33420472 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 33420472 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 33420472 — Biomarker: Intercellular adhesion molecule 1
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: ICAM1
Study 32423746 — Biomarker: Eosinophil cationic protein
Type: Safety Biomarker (SAF)
Genes: RNASE3; ECP; RNS3
Study 32423746 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35329235 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32470710 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33543381 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 33543381 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32921680 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32921680 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36153496 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33446564 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33878954 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 33066601 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33823285 — Biomarker: DLL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLL3
Study 36419123 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 35644960 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34946280 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35983527 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35983527 — Biomarker: MTTP mRNA
Type: Predictive Biomarker (PRD)
Genes: MTTP; MTP
Study 33231007 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 36196711 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36196711 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34336625 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32305727 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 32305727 — Biomarker: RSPO2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RSPO2; UNQ9384/PRO34209
Study 32006006 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32462483 — Biomarker: CLNK mRNA
Type: Predictive Biomarker (PRD)
Genes: CLNK; MIST
Study 32476162 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 32476162 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study 35594631 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 32675261 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 33863679 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36325594 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 34112266 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 32007230 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES