AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32543706 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35006243 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32125188 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 32125188 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35074904 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33271891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34881930 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 34819115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34611065 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34611065 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 32319204 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33122738 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33122738 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33122738 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 33122738 — Biomarker: IL16
Type: Safety Biomarker (SAF)
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 32794259 — Biomarker: Fibroblast growth factor 19
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF19; UNQ334/PRO533
Study 34521108 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32948200 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 33247306 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 32291620 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33034409 — Biomarker: RNPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RNPC3; KIAA1839; RBM40; RNP; SNRNP65
Study 33509019 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 32597565 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32546648 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32546648 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32710602 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 36170550 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32726200 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32176092 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36468403 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36317751 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 33017456 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33017456 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33017456 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32195538 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32195538 — Biomarker: ANGPTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32195538 — Biomarker: Angiopoietin-related protein 4
Type: Predictive Biomarker (PRD)
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 32195538 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 32195538 — Biomarker: GCKR mRNA
Type: Predictive Biomarker (PRD)
Genes: GCKR
Study 32195538 — Biomarker: LPL mRNA
Type: Predictive Biomarker (PRD)
Genes: LPL; LIPD
Study 35287025 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 32865108 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35608639 — Biomarker: TNFRSF9 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF9; CD137; ILA
Study 35608639 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34648847 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 32996010 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33351781 — Biomarker: TIGIT mRNA
Type: Predictive Biomarker (PRD)
Genes: TIGIT; VSIG9; VSTM3
Study 33351781 — Biomarker: KLRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 33351781 — Biomarker: GZMB mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 33351781 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 34506606 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32791692 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33938492 — Biomarker: RALA mRNA
Type: Predictive Biomarker (PRD)
Genes: RALA; RAL
Study 34544820 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 35083878 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33121452 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 33744088 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 36219809 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32473563 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 32473563 — Biomarker: CNTF mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTF
Study 32473563 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 32473563 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34935407 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33315342 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 33652129 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 32132590 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 33301990 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32147440 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 36090495 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33343579 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 33343579 — Biomarker: HLA-A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33343579 — Biomarker: HLA-C
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HLA-JY3, D6S204, PSORS1
Study 33343579 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 35397367 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35397367 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33113535 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 32067218 — Biomarker: MANF mRNA
Type: Predictive Biomarker (PRD)
Genes: MANF; ARMET; ARP
Study 35608580 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35608580 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35608580 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35608580 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32409838 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34341520 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 34341520 — Biomarker: Annualized growth velocity
Type: Surrogate Endpoint (SUR)
Study 33923532 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 35242209 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 35242209 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 32491923 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 35120199 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33059911 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 32681739 — Biomarker: Hematologic response
Type: Surrogate Endpoint (SUR)
Study 33503302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34962559 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34811502 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 34880957 — Biomarker: TSN mRNA
Type: Predictive Biomarker (PRD)
Genes: TSN
Study 34880957 — Biomarker: miR-205
Type: Safety Biomarker (SAF)
Genes: MIR205
Study 35986934 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 35484744 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35484744 — Biomarker: miR-106a
Type: Predictive Biomarker (PRD)
Genes: MIR106A
Study 35484744 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32295092 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 33574076 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 616063739 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35897022 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33977310 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 35873227 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 32861275 — Biomarker: TNFRSF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32861275 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32861275 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35561315 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33295397 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32740409 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34344427 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34344427 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34246303 — Biomarker: PAX7 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAX7; HUP1
Study 34246303 — Biomarker: MYOD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 33256456 — Biomarker: PCSK5 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK5; PC5; PC6
Study 35662283 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 35662283 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33761458 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33761458 — Biomarker: AIP mRNA
Type: Predictive Biomarker (PRD)
Genes: AIP; XAP2
Study 33761458 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33761458 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33761458 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36342113 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33323188 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 34445008 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 33866774 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 33548084 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35969408 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33186774 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33186774 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36727153 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 36350593 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32609331 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34620496 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 33268527 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35819787 — Biomarker: FANCE mRNA
Type: Predictive Biomarker (PRD)
Genes: FANCE; FACE
Study 33780749 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33027448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33027448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33452059 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 33212268 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 33212268 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32737344 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32975556 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32789480 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 32789480 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 32789480 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34515079 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 33407848 — Biomarker: Exhaled carbon monoxide
Type: Surrogate Endpoint (SUR)
Study 35809206 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34792562 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 34792562 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34792562 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32168067 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 32212089 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32212089 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32402609 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 33060491 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33060491 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 33060491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35389428 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35279972 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32060260 — Biomarker: DLEU7 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLEU7; LEU7
Study 32060260 — Biomarker: MSRB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MSRB3; UNQ1965/PRO4487
Study 32063059 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32267205 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32532687 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32167794 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32167794 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 33686407 — Biomarker: POR mRNA
Type: Predictive Biomarker (PRD)
Genes: POR; CYPOR
Study 35477876 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36240972 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33614699 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 33614699 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32392715 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33470646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32367437 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 32367437 — Biomarker: TERT mRNA
Type: Predictive Biomarker (PRD)
Genes: TERT; EST2; TCS1; TRT
Study 32367437 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 35098682 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33076902 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35021015 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32517192 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 32517192 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32517192 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 33037656 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 33037656 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34150674 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34150674 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 35833298 — Biomarker: CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CR1; C3BR
Study 34228086 — Biomarker: PRCP mRNA
Type: Predictive Biomarker (PRD)
Genes: PRCP; PCP
Study 32755065 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 32375688 — Biomarker: PTGDS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTGDS; PDS
Study 32375688 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32375688 — Biomarker: IDS mRNA
Type: Predictive Biomarker (PRD)
Genes: IDS; SIDS
Study 35569564 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35569564 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 32762115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32762115 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 33516644 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 33516644 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 33516644 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36454825 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33704913 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36169441 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36169441 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36169441 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35389424 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32118823 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32118823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32382745 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 32382745 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32202490 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36174028 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 36174028 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32564482 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35115706 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32349779 — Biomarker: KMT2D mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2D; ALR; MLL2; MLL4
Study 32349779 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 32349779 — Biomarker: CREBBP mRNA
Type: Predictive Biomarker (PRD)
Genes: CREBBP; CBP
Study 32349779 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 35100493 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 35568917 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 35872936 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 35872936 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 35872936 — Biomarker: miR-137
Type: Safety Biomarker (SAF)
Genes: MIR137
Study 33840495 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35486013 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35486013 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35486013 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 34299780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34299780 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)