AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 33993740 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 35059248 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 34839601 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32584199 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32584199 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32584199 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32584199 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32584199 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35114798 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36311525 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 35847786 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 33675342 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35436142 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32540725 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33196921 — Biomarker: CD37 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD37; TSPAN26
Study 32512262 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35039206 — Biomarker: FDPS mRNA
Type: Predictive Biomarker (PRD)
Genes: FDPS; FPS; KIAA1293
Study 33556442 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33630072 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35176038 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 35176038 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35728577 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32124801 — Biomarker: TLR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR2; TIL4
Study 32124801 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 32124801 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 32124801 — Biomarker: IL4 mRNA
Type: Monitoring Biomarker (MOI)
Genes: IL4
Study 32124801 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 32124801 — Biomarker: RLN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: RLN2
Study 32199708 — Biomarker: Serum sodium
Type: Surrogate Endpoint (SUR)
Study 36243884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34635114 — Biomarker: Plasma ammonia
Type: Surrogate Endpoint (SUR)
Study 33429977 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 33429977 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 33573042 — Biomarker: NRG4 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRG4
Study 33423267 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 33423267 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 32712674 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study 32921111 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 35874678 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35850110 — Biomarker: C1QL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 32054473 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34481017 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 33757723 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34427156 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34708639 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34708639 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32041914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32041914 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 34429149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35292490 — Biomarker: ZDHHC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZDHHC2; REAM; REC; ZNF372
Study 33143764 — Biomarker: NPY mRNA
Type: Predictive Biomarker (PRD)
Genes: NPY
Study 33143764 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 36079902 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33874993 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 36274326 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34081076 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 32875383 — Biomarker: RUNX1T1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 34310044 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35851507 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34085474 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34085474 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 34085474 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33414406 — Biomarker: OMG mRNA
Type: Predictive Biomarker (PRD)
Genes: OMG; OMGP
Study 36301337 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 36301337 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 36195687 — Biomarker: SEMA4D mRNA
Type: Predictive Biomarker (PRD)
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study 33494805 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 34209600 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33040141 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35507017 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 35507017 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 35507017 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33649927 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 36224375 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33283667 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 33291798 — Biomarker: DMTN mRNA
Type: Predictive Biomarker (PRD)
Genes: DMTN; DMT; EPB49
Study 33220004 — Biomarker: LRRC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRRC4; BAG; NAG14; UNQ554/PRO1111
Study 33871558 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 36444922 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36135380 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34781136 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35309285 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study 32312223 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 32312223 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32312223 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35136033 — Biomarker: ATAD3B mRNA
Type: Predictive Biomarker (PRD)
Genes: ATAD3B; KIAA1273; TOB3
Study 35136033 — Biomarker: SKIL mRNA
Type: Predictive Biomarker (PRD)
Genes: SKIL; SNO
Study 35707974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32045493 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 33586924 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 34987601 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 33327260 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33382448 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 34301751 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34301751 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 33856729 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33856729 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35192645 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 33180211 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32476236 — Biomarker: BLM mRNA
Type: Predictive Biomarker (PRD)
Genes: BLM; RECQ2; RECQL3
Study 33540206 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 33144354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33486203 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32309857 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 32779141 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 35760319 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 34653398 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 35728909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32363929 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 32363929 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study 32363929 — Biomarker: CCR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 33059105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34471542 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33416918 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34004448 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35104057 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33397249 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33397249 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33397249 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33397249 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33397249 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33397249 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 32800508 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32800508 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 32800508 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35404972 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 32312326 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 32813842 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34259565 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36017934 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 36017934 — Biomarker: IL-6 and IL-10
Type: Safety Biomarker (SAF)
Study 36017934 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 35872770 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 35762321 — Biomarker: PLA2G1B mRNA
Type: Predictive Biomarker (PRD)
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 35762321 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35762321 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35762321 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33288862 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 35058583 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34363033 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 32202330 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32202330 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35457683 — Biomarker: PTBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTBP2; NPTB; PTB; PTBLP
Study 35596636 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36368914 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32578813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32578813 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32473378 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 34130029 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34130029 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34130029 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36229975 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 36229975 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 32909259 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 32909259 — Biomarker: MCIDAS mRNA
Type: Predictive Biomarker (PRD)
Genes: MCIDAS; IDAS; MCI; MCIN
Study 35290813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 616702026 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34635066 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34635066 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35835616 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 35835616 — Biomarker: NRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NRN1; NRN
Study 35803469 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 35482790 — Biomarker: ERFE mRNA
Type: Predictive Biomarker (PRD)
Genes: ERFE; C1QTNF15; CTRP15; FAM132B
Study 33536190 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 33536190 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 33536190 — Biomarker: AKT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT2
Study 33536190 — Biomarker: AKT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT3; PKBG
Study 34195574 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 35475975 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 32588760 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 32588760 — Biomarker: AZU1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZU1
Study 32588760 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32588760 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 32588760 — Biomarker: VGF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: VGF
Study 35853975 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 32014581 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 34987129 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34987129 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33849138 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33849138 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32278195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32278195 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 32278195 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 32278195 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36220809 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 36053828 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32171508 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33998210 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33215209 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35509099 — Biomarker: TRPA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPA1; ANKTM1
Study 35509099 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study 36113828 — Biomarker: APCS mRNA
Type: Predictive Biomarker (PRD)
Genes: APCS; PTX2
Study 36113828 — Biomarker: SDC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDC2; HSPG1
Study 36113828 — Biomarker: SFRP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study 34592949 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 33568368 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32801130 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34407626 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36181990 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36181990 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36644821 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 36644821 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33755862 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33755862 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 33755862 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 33755862 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34514701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33101444 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33101444 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33101444 — Biomarker: TRAF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF6; RNF85
Study 33101444 — Biomarker: FN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FN1; FN
Study 33101444 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 33101444 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34626550 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33263641 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35706488 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 34106303 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36351465 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32761160 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)