AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35638392 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35638392 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32842955 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35491532 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34749770 — Biomarker: COL7A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: COL7A1
Study 32101872 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 32101872 — Biomarker: ADRB2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADRB2; ADRB2R; B2AR
Study 32101872 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32991991 — Biomarker: LYZ mRNA
Type: Predictive Biomarker (PRD)
Genes: LYZ; LZM
Study 32991991 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 32991991 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32991991 — Biomarker: CASP9
Type: Predictive Biomarker (PRD)
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 34763914 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 34252573 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33191854 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 33191854 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35440941 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 34952447 — Biomarker: GDNF mRNA
Type: Predictive Biomarker (PRD)
Genes: GDNF
Study 33166032 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33166032 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33166032 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35932536 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 35932536 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35932536 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34430349 — Biomarker: GAGE7 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAGE7; GAGE12I; GAGE7B
Study 34430349 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 34091804 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 34044633 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 34044633 — Biomarker: IL19 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL19; ZMDA1
Study 32055002 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 35995418 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35995418 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32548286 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33636027 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 33636027 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32883328 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32883328 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32883328 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34436521 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 33189801 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 32800891 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32800891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32051312 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33871635 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34475868 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34551650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36094783 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35631257 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34186278 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35630079 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 35630079 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32178765 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32178765 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33055515 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 32198301 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 32725073 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 32725073 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 34496928 — Biomarker: SP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP6; KLF14
Study 32965787 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 33071982 — Biomarker: FABP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP4
Study 33071982 — Biomarker: FABP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP5
Study 35384909 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35384909 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33992229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34791068 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34785078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32601973 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 33830898 — Biomarker: AWAT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 35778473 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34503985 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 35364051 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 34247040 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33248975 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32429680 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32429680 — Biomarker: Cyclic adenosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 35678328 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33657282 — Biomarker: BMPER mRNA
Type: Predictive Biomarker (PRD)
Genes: BMPER; KIAA1965
Study 33657282 — Biomarker: TMEM43 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMEM43; UNQ2564/PRO6244
Study 33657282 — Biomarker: XPC mRNA
Type: Predictive Biomarker (PRD)
Genes: XPC; XPCC
Study 33657282 — Biomarker: TOMM40 mRNA
Type: Predictive Biomarker (PRD)
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 33657282 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 34276288 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 33030846 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 33030846 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33437904 — Biomarker: T-cell specific protein RANTES
Type: Safety Biomarker (SAF)
Genes: CCL5; D17S136E; SCYA5
Study 33437904 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33437904 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 35719707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32687612 — Biomarker: ALDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ALDH2; ALDM
Study 32687612 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32520623 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32520623 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 32520623 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34856759 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 32677982 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32306943 — Biomarker: POMP mRNA
Type: Predictive Biomarker (PRD)
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 35889834 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 33335323 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33335323 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34836240 — Biomarker: 40S ribosomal protein S6
Type: Predictive Biomarker (PRD)
Genes: RPS6; OK/SW-cl.2
Study 33371107 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35020038 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34684312 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34684312 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34002611 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34133348 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 33559895 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33390481 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33390481 — Biomarker: DNA topoisomerase I
Type: Pharmacodynamic Biomarker (PDY)
Genes: TOP1
Study 36395695 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 32991656 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 35647831 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35647831 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35647831 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34213061 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 33764994 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 33764994 — Biomarker: HSPA5 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA5; GRP78
Study 33764994 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32613329 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33744327 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 33744327 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 32140784 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35036429 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35036429 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34965945 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34965945 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34965945 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36378778 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36378778 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35367070 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 35367070 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 33676590 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35861762 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34936984 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34936984 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34936984 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32888339 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 35670658 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 34559058 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34559058 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35026070 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35183242 — Biomarker: Nerve excitability testing
Type: Pharmacodynamic Biomarker (PDY)
Study 36457073 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33421230 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34536949 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 32621877 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 32938620 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32938620 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34694437 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 34915109 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34915109 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 34654905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32347777 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 32347777 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 34871580 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 35791734 — Biomarker: F2RL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F2RL3; PAR4
Study 33148479 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33148479 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33148479 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33941921 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33941921 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 33941921 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 32172602 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32469260 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32469260 — Biomarker: SELENBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENBP1; SBP
Study 32912274 — Biomarker: FES mRNA
Type: Predictive Biomarker (PRD)
Genes: FES; FPS
Study 32912274 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32912274 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 36366308 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 34086514 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33068349 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35473348 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34187853 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 36165862 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36165862 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36165862 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34153543 — Biomarker: MBP mRNA
Type: Predictive Biomarker (PRD)
Genes: MBP
Study 34364385 — Biomarker: Carbonic anhydrase IX
Type: Predictive Biomarker (PRD)
Genes: CA9; G250; MN
Study 34364385 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 34364385 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 34364385 — Biomarker: GAS6 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAS6; AXLLG
Study 34364385 — Biomarker: AXL mRNA
Type: Predictive Biomarker (PRD)
Genes: AXL; UFO
Study 34364385 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34364385 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 35500450 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 32033078 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32033078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33090910 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34154433 — Biomarker: Fibroblast growth factor 1
Type: Safety Biomarker (SAF)
Genes: FGF1
Study 35555099 — Biomarker: DMRT1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DMRT1; DMT1
Study 34453952 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33909773 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33909773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33547218 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 33040439 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 33294804 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34949538 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study 33834520 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33059108 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 33059108 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33989767 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33538790 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34487750 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 34487750 — Biomarker: ASRGL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASRGL1; ALP; CRASH
Study 33929389 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 32389532 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35405991 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33184627 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34762376 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 33386898 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33386898 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34265631 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33684086 — Biomarker: IGFBP7 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP7; MAC25; PSF
Study 33168806 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34889205 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 34889205 — Biomarker: IGFBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFBP2; BP2; IBP2
Study 32816246 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 34637478 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32651892 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35829980 — Biomarker: AZIN2 mRNA
Type: Predictive Biomarker (PRD)
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 33675347 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32273169 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 35792881 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 35667420 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33789284 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33789284 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32539076 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 34245777 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34245777 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34570596 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2