AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35764992 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32687695 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 32701903 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35933563 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34521624 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34419680 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32828825 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 32828825 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33546045 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35334923 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32501868 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32501868 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32501868 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32501868 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 32546198 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33858855 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 33858855 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 33181508 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33181508 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33181508 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34389273 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 34389273 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 33040565 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 35789270 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 35789270 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34090625 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34090625 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 33070223 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34118388 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34707496 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35373729 — Biomarker: MYB mRNA
Type: Predictive Biomarker (PRD)
Genes: MYB
Study 35373729 — Biomarker: HNF1A mRNA
Type: Predictive Biomarker (PRD)
Genes: HNF1A; TCF1
Study 35373729 — Biomarker: MAPK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK3; ERK1; PRKM3
Study 33847634 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 34650034 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34650034 — Biomarker: DSPP mRNA
Type: Predictive Biomarker (PRD)
Genes: DSPP
Study 34650034 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34650034 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 33569770 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34257640 — Biomarker: CARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARS1; CARS
Study 35332062 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32917529 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 34162831 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 33301018 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35018575 — Biomarker: MYF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: MYF6; BHLHC4; MRF4
Study 35018575 — Biomarker: DCN mRNA
Type: Predictive Biomarker (PRD)
Genes: DCN; SLRR1B
Study 34737064 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 34737064 — Biomarker: FGF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF18; UNQ420/PRO856
Study 33281083 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34526921 — Biomarker: LTB4R mRNA
Type: Predictive Biomarker (PRD)
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 32548915 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 35944747 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32701140 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32701140 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36282530 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 32673171 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 36236307 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34939397 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 32988827 — Biomarker: NKRF mRNA
Type: Predictive Biomarker (PRD)
Genes: NKRF; ITBA4; NRF
Study 35131452 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35131452 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35131452 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36191176 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 32285723 — Biomarker: EIF2AK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: EIF2AK2; PKR; PRKR
Study 33347677 — Biomarker: EMB mRNA
Type: Predictive Biomarker (PRD)
Genes: EMB
Study 33744617 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34049911 — Biomarker: PICALM mRNA
Type: Predictive Biomarker (PRD)
Genes: PICALM; CALM
Study 33151266 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33151266 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34788571 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 34788571 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34204400 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34204400 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32820334 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32820334 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32202637 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 35719236 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34023797 — Biomarker: PAM mRNA
Type: Predictive Biomarker (PRD)
Genes: PAM
Study 34563096 — Biomarker: Nucleotide triphosphate diphosphatase NUDT15
Type: Safety Biomarker (SAF)
Genes: NUDT15; MTH2
Study 34563096 — Biomarker: Thiopurine S-methyltransferase
Type: Safety Biomarker (SAF)
Genes: TPMT
Study 34530254 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 34460948 — Biomarker: Th2 cell
Type: Safety Biomarker (SAF)
Study 34370656 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34537124 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35590284 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32917784 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32917784 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 34923559 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 32184305 — Biomarker: WEE1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WEE1
Study 33955686 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 33955686 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 33955686 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 32438192 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32438192 — Biomarker: miR-30a-5p
Type: Safety Biomarker (SAF)
Genes: MIR30A
Study 33812492 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 33172883 — Biomarker: CALR mRNA
Type: Predictive Biomarker (PRD)
Genes: CALR; CRTC
Study 33172883 — Biomarker: Phospholipase A2 inhibitory protein
Type: Predictive Biomarker (PRD)
Genes: ANXA1; ANX1; LPC1
Study 33172883 — Biomarker: LRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1; A2MR; APR
Study 32319313 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35250032 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 34496669 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33497075 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33497075 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35594613 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 33006394 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 35607441 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33958973 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 33958973 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 33958973 — Biomarker: Cytotoxic T-lymphocyte protein 4
Type: Safety Biomarker (SAF)
Genes: CTLA4; CD152
Study 32772383 — Biomarker: SLC6A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC6A3; DAT1
Study 32772383 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 32772383 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 35587847 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 34282125 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 34282125 — Biomarker: FKBP5 mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: FKBP5; AIG6; FKBP51
Study 34282125 — Biomarker: NR3C1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NR3C1; GRL
Study 34282125 — Biomarker: SDK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SDK1
Study 34282125 — Biomarker: MAD1L1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAD1L1; MAD1; TXBP181
Study 34024551 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32207067 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 32186107 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32186107 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 32213768 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 36191758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33040101 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32915972 — Biomarker: IDH2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH2
Study 32915972 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 32915972 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32915972 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 32943750 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 32943750 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 32943750 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 32943750 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 32943750 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 33047455 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 33047455 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 35984171 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33693552 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33376568 — Biomarker: PIP mRNA
Type: Predictive Biomarker (PRD)
Genes: PIP; GCDFP15; GPIP4
Study 35871088 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 35560631 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33984593 — Biomarker: Cyclin-dependent kinase inhibitor 1
Type: Safety Biomarker (SAF)
Genes: CDKN1A
Study 33984593 — Biomarker: CDKN1B mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN1B; KIP1; p27
Study 33984593 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 33984593 — Biomarker: AKT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKT1; PKB; RAC
Study 32702748 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 34494112 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36228177 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33031175 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36939661 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 32493344 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 32493344 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32493344 — Biomarker: SOD2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SOD2
Study 32493344 — Biomarker: PECAM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PECAM1
Study 32493344 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32493344 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 32493344 — Biomarker: NANOS3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NANOS3; NOS3
Study 32493344 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 615261555 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 615261555 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33876883 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35511285 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35511285 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35511285 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33761625 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34709659 — Biomarker: GNS mRNA
Type: Predictive Biomarker (PRD)
Genes: GNS
Study 35963491 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 36054285 — Biomarker: HBG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HBG1; PRO2979
Study 32447618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32640097 — Biomarker: AGA mRNA
Type: Predictive Biomarker (PRD)
Genes: AGA
Study 33651091 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 34248023 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 32578850 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32578850 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34800700 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34800700 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 34800700 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33314886 — Biomarker: FGB mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGB
Study 32790701 — Biomarker: SLC4A7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 32790701 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35940551 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36315419 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36315419 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 35653145 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35653145 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35653145 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36473717 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35633027 — Biomarker: Valproic acid
Type: Pharmacodynamic Biomarker (PDY)
Study 32298662 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 35351020 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 36208780 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35930800 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35486613 — Biomarker: PYCARD mRNA
Type: Predictive Biomarker (PRD)
Genes: PYCARD; ASC; CARD5; TMS1
Study 35152576 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35152576 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33125518 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32271377 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35561963 — Biomarker: TNS1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TNS1; TNS
Study 32025830 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 36172933 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 34788822 — Biomarker: DHFR mRNA
Type: Predictive Biomarker (PRD)
Genes: DHFR
Study 34788822 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 34757487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34083576 — Biomarker: ACD mRNA
Type: Predictive Biomarker (PRD)
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35328926 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34539185 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35881893 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34303265 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 34303265 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 34303265 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32187913 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 35678134 — Biomarker: EVL mRNA
Type: Predictive Biomarker (PRD)
Genes: EVL; RNB6
Study 35678134 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35260678 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33975993 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32533723 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34167868 — Biomarker: TNF related activation protein
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 33721055 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33721055 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 33721055 — Biomarker: ARHGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF5; TIM
Study 32305794 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33453410 — Biomarker: AHNAK mRNA
Type: Predictive Biomarker (PRD)
Genes: AHNAK; PM227
Study 35460165 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 35460165 — Biomarker: SLCO1B1
Type: Safety Biomarker (SAF)
Genes: OATP-C; LST-1; OATP1B1
Study 36399721 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 36399721 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33302976 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 33302976 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35872955 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33359277 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 32729763 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)