AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 37978951 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 37979048 — Biomarker: ABR mRNA
Type: Predictive Biomarker (PRD)
Genes: ABR
Study 37979133 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37979594 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 37980367 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 37980367 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 37980875 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 37981049 — Biomarker: SLC5A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A1; NAGT; SGLT1
Study 37981049 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 37981090 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37981564 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 37981564 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 37981596 — Biomarker: TYK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TYK2
Study 37981665 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 37981892 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 37981892 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37982276 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37982276 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37982388 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37982547 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37982547 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37982575 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 37982575 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37982575 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37982827 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 37982827 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37982827 — Biomarker: GNAQ mRNA
Type: Predictive Biomarker (PRD)
Genes: GNAQ; GAQ
Study 37982827 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 37982827 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 37982827 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 37982827 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37982966 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 37983082 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 37983823 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37984453 — Biomarker: CCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCR4; CMKBR4
Study 37984741 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37984741 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37984741 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37984940 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37984956 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37985359 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37985386 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 37985817 — Biomarker: FABP5 mRNA
Type: Predictive Biomarker (PRD)
Genes: FABP5
Study 37985994 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 37986021 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37986149 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37986911 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 37986940 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 37986940 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37987186 — Biomarker: AKR1B10 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1B10; AKR1B11
Study 37987186 — Biomarker: CCL20 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL20; LARC; MIP3A; SCYA20
Study 37987893 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37987893 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37988294 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 37988449 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 37988449 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37988648 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37989943 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 37989943 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37990162 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37990163 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 37990223 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 37990224 — Biomarker: GPI mRNA
Type: Predictive Biomarker (PRD)
Genes: GPI
Study 37990670 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 37991122 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37991178 — Biomarker: STC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: STC1; STC
Study 37991639 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37991778 — Biomarker: ARHGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARHGEF5; TIM
Study 37991939 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37991939 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37993062 — Biomarker: EVC mRNA
Type: Predictive Biomarker (PRD)
Genes: EVC
Study 37993168 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study 37993199 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37993199 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37993201 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37993666 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study 37993889 — Biomarker: CA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CA3
Study 37993961 — Biomarker: KCNK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNK3; TASK; TASK1
Study 37993961 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37994400 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 37994400 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37994980 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 37995070 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37996787 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37996787 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37997800 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37997800 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 37997800 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37999656 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 37999854 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 38000815 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 38001310 — Biomarker: PTN mRNA
Type: Predictive Biomarker (PRD)
Genes: PTN; HBNF1; NEGF1
Study 38001469 — Biomarker: SLC38A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 38001469 — Biomarker: SLCO1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 38001474 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38001507 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 38004228 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38006908 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 38006908 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 38006908 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38007349 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38008001 — Biomarker: LAMA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA2; LAMM
Study 38008001 — Biomarker: SELENON mRNA
Type: Predictive Biomarker (PRD)
Genes: SELENON; SELN; SEPN1
Study 38008001 — Biomarker: SRCIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 38008001 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 38009200 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 38009241 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38009310 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38009662 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38009933 — Biomarker: CYP2B6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2B6
Study 38009933 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 38009933 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 38009933 — Biomarker: UGT2B7 mRNA
Type: Predictive Biomarker (PRD)
Genes: UGT2B7; UGTB2B9
Study 38010260 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38010260 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 38010394 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 38010394 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 38011131 — Biomarker: FAP mRNA
Type: Predictive Biomarker (PRD)
Genes: FAP
Study 38011704 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38011922 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 38011968 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38011968 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38012285 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38012327 — Biomarker: KLRC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRC2; NKG2C
Study 38012327 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38012534 — Biomarker: Adenosine deaminase
Type: Monitoring Biomarker (MOI)
Genes: ADA; ADA1
Study 38012534 — Biomarker: Antidrug antibody
Type: Pharmacodynamic Biomarker (PDY)
Study 38012534 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 38012534 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 38012795 — Biomarker: DRD2
Type: Safety Biomarker (SAF)
Study 38012835 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 38012835 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38013523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38013594 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 38014146 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 38014479 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 38014676 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38014691 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 38014691 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 38014691 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38015039 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 38015220 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38015467 — Biomarker: ERCC2
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 38015901 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38016160 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38016322 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38016482 — Biomarker: KMT2D mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2D; ALR; MLL2; MLL4
Study 38016482 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 38016718 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38016718 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38016718 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38017103 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 38017103 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 38017103 — Biomarker: WT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WT1
Study 38017103 — Biomarker: ASXL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASXL1; KIAA0978
Study 38017103 — Biomarker: U2AF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study 38017103 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 38017103 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 38017325 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 38017432 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38017482 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 38017482 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 38019014 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 38019014 — Biomarker: BCOR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCOR; KIAA1575
Study 38019014 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 38019014 — Biomarker: DNMT3A mRNA
Type: Predictive Biomarker (PRD)
Genes: DNMT3A
Study 38019014 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 38019014 — Biomarker: LRP1B mRNA
Type: Predictive Biomarker (PRD)
Genes: LRP1B; LRPDIT
Study 38019014 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 38019014 — Biomarker: KMT2C mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2C; HALR; KIAA1506; MLL3
Study 38019014 — Biomarker: NFE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NFE2
Study 38019116 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38019116 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38019287 — Biomarker: TH mRNA
Type: Predictive Biomarker (PRD)
Genes: TH; TYH
Study 38019356 — Biomarker: CCK mRNA
Type: Predictive Biomarker (PRD)
Genes: CCK
Study 38019356 — Biomarker: TRPC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPC4
Study 38019444 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 38019512 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38020201 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 38020522 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 38020587 — Biomarker: 14-3-3 protein sigma
Type: Predictive Biomarker (PRD)
Genes: SFN; HME1
Study 38023564 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38024244 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38025217 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38025971 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38025971 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38026295 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38026375 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 38027064 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 38027106 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 38027217 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 38027469 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 38028143 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38028429 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 38029357 — Biomarker: DHFR
Type: Safety Biomarker (SAF)
Genes: DHFR1
Study 38029625 — Biomarker: CACNA1C mRNA
Type: Predictive Biomarker (PRD)
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 38029807 — Biomarker: TRAF6 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRAF6; RNF85
Study 38029807 — Biomarker: MAP3K7 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K7; TAK1
Study 38030318 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 38030318 — Biomarker: Complement factor D
Type: Safety Biomarker (SAF)
Genes: CFD; DF; PFD
Study 38030318 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38030558 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 38030971 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38030975 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38031088 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 38031156 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38032247 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38032582 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38032624 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38032644 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38032644 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38033615 — Biomarker: GRIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GRIN1; NMDAR1
Study 38034378 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38034378 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38035176 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 38035363 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 38035725 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38035747 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study 38035747 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38035997 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38036712 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38036720 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 38036720 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38036930 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 38037188 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study 38037749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38037804 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38037804 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38037804 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38037839 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38037839 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38037839 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 38037839 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)