AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 35113046 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34462887 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 34684481 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32212801 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 33410912 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 33595776 — Biomarker: ACSM3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACSM3; SAH
Study 36163929 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 33604379 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34039560 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 34032505 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32830553 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 35098970 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35793982 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study 35793982 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32651132 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 35295073 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35411074 — Biomarker: TRIM32 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM32; HT2A
Study 32524424 — Biomarker: Neurofilament light polypeptide
Type: Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: NEFL; NF68; NFL
Study 33720272 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 36363460 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 32250057 — Biomarker: VDR mRNA
Type: Predictive Biomarker (PRD)
Genes: VDR; NR1I1
Study 33638612 — Biomarker: DDR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 32235773 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32235773 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33984356 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35060389 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 32018252 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34112656 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32925765 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33225995 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 32557731 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 32883322 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 34667294 — Biomarker: Mismatch negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 34667294 — Biomarker: Auditory steady-state response
Type: Pharmacodynamic Biomarker (PDY)
Study 34052211 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33135737 — Biomarker: LEAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: LEAP2
Study 35134170 — Biomarker: ANG mRNA
Type: Predictive Biomarker (PRD)
Genes: ANG; RNASE5
Study 35134170 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34321316 — Biomarker: FFAR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR1; GPR40
Study 35857127 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33568088 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32559272 — Biomarker: Serum LDL cholesterol
Type: Surrogate Endpoint (SUR)
Study 34602349 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 34602349 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 32723264 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32773013 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34096894 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 35963369 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 35920250 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 35859928 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35859928 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34313232 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32444035 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32444035 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34516655 — Biomarker: HSPA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPA2
Study 34516655 — Biomarker: Sperm parameters
Type: Surrogate Endpoint (SUR)
Study 35656824 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 35656824 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33484896 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35241434 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 35988194 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35988194 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35988194 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 32918135 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33252489 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 616277788 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33526728 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34814819 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34474433 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34474433 — Biomarker: RAB11FIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAB11FIP1; RCP
Study 32967775 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32219386 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32219386 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 33465658 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 33465658 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33465658 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33465658 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 35688618 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35988343 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 33590947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34890069 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35876047 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32403934 — Biomarker: Pentraxin-related protein PTX3
Type: Safety Biomarker (SAF)
Genes: PTX3; TNFAIP5; TSG14
Study 32403934 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32403934 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32554646 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36357960 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 36130275 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36130275 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study 32915800 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 33854404 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 33854404 — Biomarker: CD80 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 33854404 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32480364 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 34120912 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 33272980 — Biomarker: IGF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGF1; IBP1
Study 33272980 — Biomarker: Antithrombin-III
Type: Safety Biomarker (SAF)
Genes: SERPINC1; AT3; PRO0309
Study 35467561 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34431828 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34960037 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34960037 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34453873 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34453873 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34405232 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 36495185 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36495185 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33259482 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33285652 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 35332291 — Biomarker: ETV5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ETV5; ERM
Study 35332291 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 34323164 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 32827162 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 33598693 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 35385061 — Biomarker: DOCK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DOCK3; KIAA0299; MOCA
Study 33085170 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 33081788 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33896590 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33896590 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 36178169 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 34183565 — Biomarker: SERPINA7 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA7; TBG
Study 34183565 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 34183565 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 35567872 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34110902 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 34187938 — Biomarker: LARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LARS1; KIAA1352; LARS
Study 34340708 — Biomarker: HIPK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: HIPK2
Study 34340708 — Biomarker: PPP1CC mRNA
Type: Predictive Biomarker (PRD)
Genes: PPP1CC
Study 34765938 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 36075590 — Biomarker: DLL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: DLL4; UNQ1895/PRO4341
Study 36075590 — Biomarker: Adrenomedullin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: ADM; AM
Study 35842871 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 36107485 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 35639038 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32077525 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34368894 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 34368894 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 34368894 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 34368894 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34368894 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 32605893 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34562081 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34774089 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32228673 — Biomarker: EMP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EMP1; B4B; TMP
Study 32471729 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 32700098 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 34462286 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 34285006 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32278278 — Biomarker: SLC6A4 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: SLC6A4; HTT; SERT
Study 36017028 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 36017028 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 32768592 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 35499569 — Biomarker: TNFRSF18 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 33553097 — Biomarker: EED mRNA
Type: Predictive Biomarker (PRD)
Genes: EED
Study 33156550 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 35226949 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34960007 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34960007 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 32736776 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 32736776 — Biomarker: Plasminogen activator inhibitor
Type: Safety Biomarker (SAF)
Genes: SERPINE1; PAI1; PLANH1
Study 32966830 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 33711671 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 616497225 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 616497225 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34783447 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 34783447 — Biomarker: HMGCR mRNA
Type: Predictive Biomarker (PRD)
Genes: HMGCR
Study 33795720 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 34028298 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 35648242 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34077644 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 32000559 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 33232739 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32755254 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33740276 — Biomarker: CBS mRNA
Type: Predictive Biomarker (PRD)
Genes: CBS
Study 34887572 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33663581 — Biomarker: KLHL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLHL17; AF
Study 33663581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33663581 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32152335 — Biomarker: ADIPOQ mRNA
Type: Predictive Biomarker (PRD)
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 32492302 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35973626 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32666238 — Biomarker: TPR mRNA
Type: Predictive Biomarker (PRD)
Genes: TPR
Study 35467140 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 32324197 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 34267006 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34980810 — Biomarker: TLR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR4
Study 34980810 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 33372280 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 32019575 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 34274848 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34274848 — Biomarker: CFH mRNA
Type: Predictive Biomarker (PRD)
Genes: CFH; HF; HF1; HF2
Study 35700741 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 32034070 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 37027131 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37027131 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33522249 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 33522249 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 33522249 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 34821943 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35186297 — Biomarker: ERAS mRNA
Type: Predictive Biomarker (PRD)
Genes: ERAS; HRAS2; HRASP
Study 34152804 — Biomarker: MYCN mRNA
Type: Predictive Biomarker (PRD)
Genes: MYCN; BHLHE37; NMYC
Study 34152804 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 34019661 — Biomarker: Serum alkaline phosphatase
Type: Surrogate Endpoint (SUR)
Study 34920097 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 36972981 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34620312 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35998839 — Biomarker: MAP3K15 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K15; ASK3
Study 35998839 — Biomarker: MAPK10 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAPK10; JNK3; JNK3A; PRKM10; SAPK1B
Study 35998839 — Biomarker: ADAMTS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ADAMTS1; KIAA1346; METH1
Study 34224503 — Biomarker: UBB mRNA
Type: Predictive Biomarker (PRD)
Genes: UBB
Study 36153281 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36153281 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36098670 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 33666540 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 35881420 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32119192 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 33342316 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33059620 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 34087678 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33357480 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 32699180 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 32623925 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35915733 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32638504 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32638504 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 33298617 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32527283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32306007 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36434692 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 34738551 — Biomarker: Neutrophil gelatinase-associated lipocalin
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: LCN2; HNL; NGAL
Study 34738551 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 34738551 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 34738551 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 32543706 — Biomarker: BMP6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BMP6; VGR