AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study NCT04784182 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04962022 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05718323 — Biomarker: SLFN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLFN11
Study NCT05703815 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study NCT05703815 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study NCT06277466 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT05403346 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05064852 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study NCT05326984 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study NCT05326984 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study NCT06540924 — Biomarker: LBX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LBX1; LBX1H
Study NCT06540924 — Biomarker: TIMP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP2
Study NCT06540924 — Biomarker: CHD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHD7; KIAA1416
Study NCT05711004 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05833763 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study NCT06431152 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT04513223 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04695795 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study NCT04695795 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05265091 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05132907 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05530265 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04951817 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06700876 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study NCT05493917 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06703008 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04639310 — Biomarker: KCNQ2 mRNA
Type: Predictive Biomarker (PRD)
Genes: KCNQ2
Study NCT00002369 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT06048718 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06048718 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04938583 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT04353180 — Biomarker: TMPRSS2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS2; PRSS10
Study NCT04353180 — Biomarker: ACE2 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACE2; UNQ868/PRO1885
Study NCT04353180 — Biomarker: TLR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR3
Study NCT04353180 — Biomarker: MAVS mRNA
Type: Predictive Biomarker (PRD)
Genes: MAVS; IPS1; KIAA1271; VISA
Study NCT04353180 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04353180 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04353180 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05489991 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05855707 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT06029348 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06035016 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06035016 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06035016 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study NCT06354972 — Biomarker: ASPRV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASPRV1; SASP
Study NCT06189521 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05098067 — Biomarker: TRPV1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRPV1; VR1
Study NCT06318949 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03473288 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04869826 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05557487 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05557487 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT05557487 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study NCT06105008 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06105008 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06105008 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT06105008 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT04432090 — Biomarker: GPR119 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR119
Study NCT05910996 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study NCT06643416 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06643416 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study NCT06643416 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT06183658 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06183658 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study NCT05494723 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT05995028 — Biomarker: CD7 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD7
Study NCT05640193 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06653361 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05489523 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study NCT06655662 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study NCT06588946 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06590246 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study NCT06586372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06587074 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05304351 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06604390 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06604390 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study NCT06604390 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study NCT06604390 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04949490 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT00016783 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study NCT04948554 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04753073 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT04806464 — Biomarker: IL15 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL15
Study NCT06300476 — Biomarker: ABCA4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ABCA4; ABCR
Study NCT05133388 — Biomarker: HBB mRNA
Type: Predictive Biomarker (PRD)
Genes: HBB
Study NCT04484077 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT06213857 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT06213857 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study NCT06567483 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05998421 — Biomarker: Blood coagulation
Type: Pharmacodynamic Biomarker (PDY)
Study NCT04557891 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study NCT06380491 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04316442 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT05596032 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT05809024 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study NCT05809024 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT05809024 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05210998 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study NCT05753943 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT06266247 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study NCT04586283 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05046509 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT06243536 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study NCT05362955 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study NCT06651255 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study NCT06118086 — Biomarker: MYB mRNA
Type: Predictive Biomarker (PRD)
Genes: MYB
Study NCT05304702 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT04971434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05039086 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study NCT04737655 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study NCT05994274 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study NCT04578444 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04578444 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study NCT03206814 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04591483 — Biomarker: ELOVL4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ELOVL4
Study NCT06451406 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT06653972 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06587503 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study NCT03492918 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study NCT03492918 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT05075070 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06366139 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study NCT06007300 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study NCT06601153 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study NCT06591793 — Biomarker: MYO7A mRNA
Type: Predictive Biomarker (PRD)
Genes: MYO7A; USH1B
Study NCT04743102 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study NCT06543199 — Biomarker: FGG mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGG; PRO2061
Study NCT06543199 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05520970 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06617351 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT06586359 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study NCT06620913 — Biomarker: DPYSL5 mRNA
Type: Predictive Biomarker (PRD)
Genes: DPYSL5; CRMP5; ULIP6
Study NCT05650736 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT05522491 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT06620588 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study NCT06620588 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study NCT05080023 — Biomarker: CFI mRNA
Type: Predictive Biomarker (PRD)
Genes: CFI; IF
Study NCT06408454 — Biomarker: Interleukin 17
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: IL17A; CTLA8; IL17
Study NCT06678191 — Biomarker: LAMA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAMA1; LAMA
Study NCT04697875 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study NCT04697875 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04365517 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study NCT04365517 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT06011187 — Biomarker: AFM mRNA
Type: Predictive Biomarker (PRD)
Genes: AFM; ALB2; ALBA
Study NCT06541860 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT05430399 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04824924 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study NCT05895136 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04322383 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study NCT05828147 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study NCT05828147 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study NCT05599893 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study NCT06201780 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study NCT06201780 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study NCT06201780 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study NCT06201780 — Biomarker: JAK2
Type: Predictive Biomarker (PRD)
Genes: JTK10
Study NCT05684627 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study NCT05445778 — Biomarker: Folate receptor alpha
Type: Predictive Biomarker (PRD)
Genes: FOLR1; FOLR
Study NCT05517252 — Biomarker: MIP mRNA
Type: Predictive Biomarker (PRD)
Genes: MIP; AQP0
Study NCT06234605 — Biomarker: VHL mRNA
Type: Predictive Biomarker (PRD)
Genes: VHL
Study NCT04633278 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05085626 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05308602 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT06567080 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT06517667 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT05928195 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06236269 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06236269 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06236269 — Biomarker: TACSTD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT04098718 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study NCT05447767 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study NCT05761028 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study NCT04886232 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT04960774 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study NCT04960774 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study NCT06200103 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06041425 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT05964582 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05858307 — Biomarker: AMH mRNA
Type: Predictive Biomarker (PRD)
Genes: AMH; MIF
Study NCT04640909 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study NCT05601401 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06498076 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT04989231 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study NCT05092451 — Biomarker: IL15 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL15
Study NCT04978675 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04815356 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study NCT05893927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06087055 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study NCT05785754 — Biomarker: CD93 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD93; C1QR1; MXRA4
Study NCT06286748 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05376514 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study NCT05376514 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT06654154 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT06654154 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study NCT06655259 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study NCT06591416 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study NCT06586177 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study NCT06497270 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT04829422 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05606913 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study NCT03063710 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study NCT03063710 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study NCT04907760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study NCT05165771 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study NCT03976973 — Biomarker: MUC2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC2; SMUC
Study NCT03976973 — Biomarker: MUC4 mRNA
Type: Predictive Biomarker (PRD)
Genes: MUC4
Study NCT03976973 — Biomarker: MUC5AC mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MUC5AC; MUC5
Study NCT03976973 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study NCT05919329 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06518278 — Biomarker: CAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAP1; CAP
Study NCT05756972 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study NCT05756972 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05169541 — Biomarker: MBL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBL2; COLEC1; MBL
Study NCT05949333 — Biomarker: Duration of severe neutropenia
Type: Surrogate Endpoint (SUR)
Study NCT04951024 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study NCT04951024 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study NCT04676386 — Biomarker: PIR mRNA
Type: Predictive Biomarker (PRD)
Genes: PIR
Study NCT05374538 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study NCT05374538 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT06095063 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05461209 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study NCT05382351 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study NCT05953701 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study NCT06548919 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study NCT06548919 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study NCT06277427 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA