AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 32511981 — Biomarker: KIT mRNA
Type: Predictive Biomarker (PRD)
Genes: KIT; SCFR
Study 32511981 — Biomarker: PDGFRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 35225819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35585281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34862643 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 34862643 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34862643 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35661214 — Biomarker: ACR mRNA
Type: Predictive Biomarker (PRD)
Genes: ACR; ACRS
Study 35661214 — Biomarker: Gamma-Histone H2AX
Type: Pharmacodynamic Biomarker (PDY)
Genes: H2AX; H2AFX
Study 35661214 — Biomarker: Urokinase plasminogen activator surface receptor
Type: Monitoring Biomarker (MOI)
Genes: PLAUR; MO3; UPAR
Study 34796837 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34796837 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 34796837 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34796837 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 34796837 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 34796837 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 34796837 — Biomarker: C-X-C motif chemokine 11
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 34796837 — Biomarker: C-X-C motif chemokine 5
Type: Safety Biomarker (SAF)
Genes: CXCL5; ENA78; SCYB5
Study 34796837 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 33068146 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35549460 — Biomarker: RAF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAF1; RAF
Study 33076805 — Biomarker: C2 mRNA
Type: Predictive Biomarker (PRD)
Genes: C2
Study 33076805 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 34581765 — Biomarker: HP mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HP
Study 34581765 — Biomarker: PNP mRNA
Type: Predictive Biomarker (PRD)
Genes: PNP; NP
Study 34581765 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 34921497 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32687296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34643642 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33248590 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33248590 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33082712 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32955138 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32955138 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33595905 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35770578 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 32109005 — Biomarker: Immunoglobulin E
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33496330 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 33962026 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 33225982 — Biomarker: Serum triglycerides
Type: Surrogate Endpoint (SUR)
Study 33225982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34174187 — Biomarker: TRIM63 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 32444091 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32164507 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32915796 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 32789528 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34690065 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36347450 — Biomarker: CARM1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CARM1; PRMT4
Study 36347450 — Biomarker: miR-192
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 36347450 — Biomarker: miR-192-5p
Type: Safety Biomarker (SAF)
Genes: MIR192
Study 35646354 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33025645 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 33338415 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 32147751 — Biomarker: OPRM1
Type: Safety Biomarker (SAF)
Genes: MOR1; MOP
Study 32147751 — Biomarker: Hypoxia-inducible factor 1-alpha
Type: Predictive Biomarker (PRD)
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 32147751 — Biomarker: EPAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 34328029 — Biomarker: STAR mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: STAR; STARD1
Study 35381069 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 34485814 — Biomarker: Mucin-1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MUC1; PUM
Study 32587591 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 32587591 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 35493119 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 33567080 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33567080 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33823506 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 32866619 — Biomarker: Nqo1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: NQO1; DIA4; NMOR1
Study 32866619 — Biomarker: Heme oxygenase 1
Type: Monitoring Biomarker (MOI)
Genes: HMOX1; HO; HO1
Study 32866619 — Biomarker: GCLC mRNA
Type: Predictive Biomarker (PRD)
Genes: GCLC; GLCL; GLCLC
Study 32929756 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 33356790 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35130850 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35130850 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 35340239 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33539242 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35796695 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 35796695 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34621327 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 34621327 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 36076498 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36076498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36076498 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37449542 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34032997 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33032071 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 34504990 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34504990 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 34504990 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 34504990 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 34504990 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 34504990 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 34504990 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 34504990 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 35691448 — Biomarker: LCT mRNA
Type: Predictive Biomarker (PRD)
Genes: LCT; LPH
Study 36229863 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 36229863 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36229863 — Biomarker: IL6
Type: Predictive Biomarker (PRD)
Genes: IL-6; BSF2; HGF; HSF
Study 36229863 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 36229863 — Biomarker: Matrix metalloproteinase 8
Type: Monitoring Biomarker (MOI)
Genes: MMP8; CLG1
Study 33401223 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 32213141 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34068848 — Biomarker: Matrix metalloproteinase 1
Type: Monitoring Biomarker (MOI)
Genes: MMP1; CLG
Study 34068848 — Biomarker: MMP-1
Type: Safety Biomarker (SAF)
Genes: MMP1
Study 35098466 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 36002048 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 32097932 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 35507141 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 34193503 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 34193503 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 32875927 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34313633 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32293463 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34906660 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 34883184 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 34883184 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36341846 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 32529884 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33613861 — Biomarker: APC mRNA
Type: Predictive Biomarker (PRD)
Genes: APC; DP2.5
Study 34115061 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35640246 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 32778788 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32093785 — Biomarker: SP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP3
Study 33486403 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 35912731 — Biomarker: HPV E2
Type: Predictive Biomarker (PRD)
Study 33589758 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33259892 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36221338 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32749459 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 35982162 — Biomarker: Vitamin B12
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 34341098 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 34341098 — Biomarker: APOB mRNA
Type: Predictive Biomarker (PRD)
Genes: APOB
Study 34341098 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35554396 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33415448 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 33940126 — Biomarker: SST mRNA
Type: Predictive Biomarker (PRD)
Genes: SST
Study 35901049 — Biomarker: FBP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBP1; FBP
Study 33682983 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 32044205 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33287715 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32825020 — Biomarker: EVC mRNA
Type: Predictive Biomarker (PRD)
Genes: EVC
Study 35334791 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 33166694 — Biomarker: NNT mRNA
Type: Predictive Biomarker (PRD)
Genes: NNT
Study 34531293 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 33789010 — Biomarker: Urinary oxalate
Type: Surrogate Endpoint (SUR)
Study 33124156 — Biomarker: TSPAN31 mRNA
Type: Predictive Biomarker (PRD)
Genes: TSPAN31; SAS
Study 33124156 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 32946590 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 34538125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32865597 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 34605319 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 32435011 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35654052 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 35654052 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 35654052 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 36314570 — Biomarker: Heat pain threshold
Type: Pharmacodynamic Biomarker (PDY)
Study 36314570 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36314570 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33130949 — Biomarker: HGS mRNA
Type: Predictive Biomarker (PRD)
Genes: HGS; HRS
Study 35767384 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 35767384 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32247951 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 32247951 — Biomarker: Mitochondrial membrane potential
Type: Pharmacodynamic Biomarker (PDY)
Study 33368307 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 36091030 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36091030 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 34047371 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32067691 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36100672 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 32569024 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 36071284 — Biomarker: FGA mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: FGA
Study 34480060 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 34480060 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35863669 — Biomarker: Interleukin 5
Type: Predictive Biomarker (PRD)
Genes: IL5
Study 35863669 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 34459060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34068687 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34269503 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 34016024 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 35001501 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35001501 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36089810 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 36089810 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 36089810 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33007353 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 34600178 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 36397221 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 36397221 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36397221 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 35341647 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 33780274 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 33780274 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 34603765 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 32147925 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 36028073 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 36028073 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 36028073 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 34307194 — Biomarker: LOX mRNA
Type: Predictive Biomarker (PRD)
Genes: LOX
Study 34307194 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 32797085 — Biomarker: CFP mRNA
Type: Predictive Biomarker (PRD)
Genes: CFP; PFC
Study 32797085 — Biomarker: PLXNA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 32797085 — Biomarker: AMD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: AMD1; AMD
Study 36112590 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 34075589 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34425071 — Biomarker: MAP3K5 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 34425071 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 34425071 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 33419872 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32217148 — Biomarker: PPARA mRNA
Type: Predictive Biomarker (PRD)
Genes: PPARA; NR1C1; PPAR
Study 32217148 — Biomarker: UCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP1; SLC25A7; UCP
Study 32217148 — Biomarker: UCP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: UCP2; SLC25A8
Study 32217148 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 32217148 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 36266163 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33766837 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32138501 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 32138501 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33461302 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35730409 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 33142467 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 33142467 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32123205 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 37045502 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 32576229 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34536258 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32156136 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32156136 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 32156136 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 33840387 — Biomarker: BNC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BNC1; BNC
Study 35605429 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32472357 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 35172440 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 35303160 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 34002910 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 35039269 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 32969605 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)