AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 37368929 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 37368929 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37368929 — Biomarker: Hepatocyte growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HGF; HPTA
Study 37369099 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37369125 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37369421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37369602 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 37369826 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 37369826 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 37370032 — Biomarker: MYRF mRNA
Type: Predictive Biomarker (PRD)
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 37370032 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 37370135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37370204 — Biomarker: GZMB mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 37372153 — Biomarker: IGHMBP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: IGHMBP2; SMBP2; SMUBP2
Study 37372153 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 37373853 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37376989 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37377385 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37377605 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37378404 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 37378860 — Biomarker: c-Jun N-terminal kinase
Type: Safety Biomarker (SAF)
Study 37378860 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 37378860 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 37378983 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 37378983 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 37379158 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 37379430 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37379430 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37379495 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 37379502 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37379764 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37380091 — Biomarker: TBCB mRNA
Type: Predictive Biomarker (PRD)
Genes: TBCB; CG22; CKAP1
Study 37380301 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37381014 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37381988 — Biomarker: TF mRNA
Type: Predictive Biomarker (PRD)
Genes: TF; PRO1400
Study 37381988 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 37382961 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 37383243 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 37384412 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37384848 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37385272 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 37385280 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 37385724 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 37385855 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37385905 — Biomarker: Serum potassium
Type: Surrogate Endpoint (SUR)
Study 37385995 — Biomarker: ROS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ROS1; MCF3; ROS
Study 37385995 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 37385995 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 37386016 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37386016 — Biomarker: MDM2 mRNA
Type: Predictive Biomarker (PRD)
Genes: MDM2
Study 37386016 — Biomarker: TP53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: p53; LFS1
Study 37386016 — Biomarker: Induced myeloid leukemia cell differentiation protein Mcl-1
Type: Predictive Biomarker (PRD)
Genes: MCL1; BCL2L3
Study 37386485 — Biomarker: C6 mRNA
Type: Predictive Biomarker (PRD)
Genes: C6
Study 37386512 — Biomarker: MAL mRNA
Type: Predictive Biomarker (PRD)
Genes: MAL
Study 37387213 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37387213 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37387213 — Biomarker: TACSTD2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study 37387272 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 37387272 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37388640 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 37388902 — Biomarker: YAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YAP1; YAP65
Study 37388902 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37390310 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37390360 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37390764 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37390764 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37390764 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 37390764 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37390800 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 37390836 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37391470 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 37391667 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 37391938 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37393120 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 37393269 — Biomarker: FMOD mRNA
Type: Predictive Biomarker (PRD)
Genes: FMOD; FM; SLRR2E
Study 37393757 — Biomarker: Vascular endothelial growth factor receptor 2
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: KDR; FLK1; VEGFR2
Study 37393757 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37394115 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37394115 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 37394627 — Biomarker: CYP1A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP1A2
Study 37394627 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 37394920 — Biomarker: F2RL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F2RL3; PAR4
Study 37395286 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 37395286 — Biomarker: TFPI mRNA
Type: Predictive Biomarker (PRD)
Genes: TFPI; LACI; TFPI1
Study 37395286 — Biomarker: TIMP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: TIMP4
Study 37395586 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37395780 — Biomarker: LSS mRNA
Type: Predictive Biomarker (PRD)
Genes: LSS; OSC
Study 37395974 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37395974 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37396307 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 37396586 — Biomarker: IVL mRNA
Type: Predictive Biomarker (PRD)
Genes: IVL
Study 37396808 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 37397078 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37397985 — Biomarker: ZNF335 mRNA
Type: Predictive Biomarker (PRD)
Genes: ZNF335
Study 37397985 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37398043 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 37398079 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 37398992 — Biomarker: YES1 mRNA
Type: Predictive Biomarker (PRD)
Genes: YES1; YES
Study 37398992 — Biomarker: SRC mRNA
Type: Predictive Biomarker (PRD)
Genes: SRC; SRC1
Study 37398992 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 37399099 — Biomarker: C-C motif chemokine 19
Type: Safety Biomarker (SAF)
Genes: CCL19; ELC; MIP3B; SCYA19
Study 37399099 — Biomarker: CCL21 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study 37399355 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 37399355 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 37399355 — Biomarker: CAMLG mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMLG; CAML; GET2
Study 37399355 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 37399456 — Biomarker: CXADR mRNA
Type: Predictive Biomarker (PRD)
Genes: CXADR; CAR
Study 37400162 — Biomarker: TAC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TAC1; NKA; NKNA; TAC2
Study 37400771 — Biomarker: NOTUM mRNA
Type: Predictive Biomarker (PRD)
Genes: NOTUM; OK/SW-CL.30
Study 37400771 — Biomarker: Chitinase-3-like protein 1
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: CHI3L1
Study 37400844 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 37400844 — Biomarker: MAP2K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP2K1; MEK1; PRKMK1
Study 37401523 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 37401523 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 37401523 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37401618 — Biomarker: Serum bactericidal antibody
Type: Surrogate Endpoint (SUR)
Study 37401774 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37402092 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 37402144 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 37402153 — Biomarker: BCR mRNA
Type: Predictive Biomarker (PRD)
Genes: BCR; BCR1; D22S11
Study 37402471 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37402471 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37403057 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 37403410 — Biomarker: Endothelin-1
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: EDN1
Study 37404160 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37405504 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37405822 — Biomarker: EP300 mRNA
Type: Predictive Biomarker (PRD)
Genes: EP300; P300
Study 37406106 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37406106 — Biomarker: MT1H mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1H
Study 37406106 — Biomarker: MT1E mRNA
Type: Predictive Biomarker (PRD)
Genes: MT1E
Study 37406106 — Biomarker: MT2A mRNA
Type: Predictive Biomarker (PRD)
Genes: MT2A; CES1; MT2
Study 37406106 — Biomarker: MSMB mRNA
Type: Predictive Biomarker (PRD)
Genes: MSMB; PRSP
Study 37406106 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 37406106 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 37406106 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37406251 — Biomarker: SDS mRNA
Type: Predictive Biomarker (PRD)
Genes: SDS; SDH
Study 37406350 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37406760 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37406777 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37407001 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37407001 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 37407040 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 37407058 — Biomarker: SLC40A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 37407113 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 37407142 — Biomarker: Tyrosine-protein kinase ABL1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ABL1; ABL; JTK7
Study 37407154 — Biomarker: Angiotensinogenase renin
Type: Pharmacodynamic Biomarker (PDY)
Genes: REN
Study 37407326 — Biomarker: Cytochrome P450 2D6
Type: Safety Biomarker (SAF)
Genes: CYP2D6; CYP2DL1
Study 37407950 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37407989 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37408044 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 37408044 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 37408044 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 37408044 — Biomarker: Macrophage inflammatory protein 1-alpha
Type: Monitoring Biomarker (MOI)
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 37408044 — Biomarker: C-C motif chemokine 4
Type: Monitoring Biomarker (MOI)
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 37408044 — Biomarker: CXCL1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 37408044 — Biomarker: CXCL2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 37408044 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 37409229 — Biomarker: CXCR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR1; CMKAR1; IL8RA
Study 37409229 — Biomarker: C-C motif chemokine 2
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CCL2; MCP1; SCYA2
Study 37409229 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37409229 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37409270 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 37409565 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 37409613 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37409757 — Biomarker: MTHFR
Type: Safety Biomarker (SAF)
Study 37409780 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 37409892 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 37410476 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 37410699 — Biomarker: Cervical intraepithelial neoplasia
Type: Surrogate Endpoint (SUR)
Study 37411039 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 37414012 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 37414060 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 37414060 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 37414062 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 37414137 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37414215 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 37414422 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 37414705 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 37414923 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37415001 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 37415001 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 37415239 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37415239 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37415246 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37415381 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 37416926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37417650 — Biomarker: PRRC2A mRNA
Type: Predictive Biomarker (PRD)
Genes: PRRC2A; BAT2; G2
Study 37417725 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37417824 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37417948 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 37417970 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 37418263 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37418304 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37418643 — Biomarker: EYS mRNA
Type: Predictive Biomarker (PRD)
Genes: EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591
Study 37419394 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 37419969 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37420006 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 37420006 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 37420006 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 37420274 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37420274 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37421291 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37421604 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 37421604 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37422688 — Biomarker: NEDD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEDD8
Study 37422688 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37422688 — Biomarker: MECOM mRNA
Type: Predictive Biomarker (PRD)
Genes: MECOM; EVI1; MDS1; PRDM3
Study 37422688 — Biomarker: PMAIP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PMAIP1; NOXA
Study 37422688 — Biomarker: Platelet glycoprotein 4
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CD36; GP3B; GP4
Study 37422772 — Biomarker: AKR1C3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 37423231 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 37423801 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37423882 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37424311 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 37424386 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 37424386 — Biomarker: CDK6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK6; CDKN6
Study 37424386 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 37424386 — Biomarker: CCND2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND2
Study 37424386 — Biomarker: CCND3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND3
Study 37424386 — Biomarker: CDKN2A mRNA
Type: Predictive Biomarker (PRD)
Genes: CDKN2A; CDKN2; MTS1
Study 37425372 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 37425721 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 37426179 — Biomarker: AR mRNA
Type: Predictive Biomarker (PRD)
Genes: AR; DHTR; NR3C4
Study 37426430 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 37426430 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37426947 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37427145 — Biomarker: DDIT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 37427145 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37428195 — Biomarker: ELN mRNA
Type: Predictive Biomarker (PRD)
Genes: ELN
Study 37428273 — Biomarker: SMAD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMAD4; DPC4; MADH4
Study 37428347 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)