AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 33405051 — Biomarker: CD28 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD28
Study 33405051 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 36429402 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33305643 — Biomarker: F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: F3
Study 33305643 — Biomarker: PSD mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36171282 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32151220 — Biomarker: Insulin receptor substrate 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: IRS1
Study 33069172 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33386756 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 35568049 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32700421 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33542371 — Biomarker: FBN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FBN1; FBN
Study 33292982 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33452595 — Biomarker: FGF21 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGF21; UNQ3115/PRO10196
Study 34922061 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34922061 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 36469833 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 33481813 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 33931884 — Biomarker: HSPB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: HSPB1; HSP27; HSP28
Study 32381158 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 32381158 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32282021 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 35141806 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 32228267 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 33022991 — Biomarker: FFAR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FFAR2; FFA2; GPCR43; GPR43
Study 34972191 — Biomarker: GZMB mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 33600826 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 32240892 — Biomarker: Ovarian carcinoma antigen CA125
Type: Monitoring Biomarker (MOI)
Genes: MUC16; CA125
Study 33745962 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 35354637 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32749942 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 32749942 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 35883115 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33976543 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33022197 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 33810414 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35430494 — Biomarker: MHC class I polypeptide-related sequence A
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MICA; PERB11.1
Study 32397113 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 32397113 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 32397113 — Biomarker: WNT3A mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: WNT3A
Study 32397113 — Biomarker: Induced myeloid leukemia cell differentiation protein Mcl-1
Type: Predictive Biomarker (PRD)
Genes: MCL1; BCL2L3
Study 34881510 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32916063 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36506062 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 36163945 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 36163945 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 32223446 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 32223446 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 35966733 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35966733 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 35401060 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35785965 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33243443 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 34103439 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33407801 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32583957 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34063455 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 34220825 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 34023405 — Biomarker: HHIP mRNA
Type: Predictive Biomarker (PRD)
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 35791295 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 33038531 — Biomarker: IL1RL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IL1RL1; DER4; ST2; T1
Study 33170536 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 34587941 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 36223105 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35710560 — Biomarker: CYP24A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP24A1; CYP24
Study 35710560 — Biomarker: SLC34A3 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC34A3; NPT2C; NPTIIC
Study 34526950 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33544719 — Biomarker: GGT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GGT1; GGT
Study 33544719 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33544719 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33544719 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32492734 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33025690 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 34256550 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 34256550 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32057907 — Biomarker: USP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: USP2; UBP41
Study 34618687 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 34618687 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 34618687 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32097286 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 35616304 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 34688915 — Biomarker: CES2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CES2; ICE
Study 34688915 — Biomarker: TRIT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TRIT1; IPT; MOD5
Study 34781656 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34114138 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 32853281 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32346959 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 35092347 — Biomarker: Liver iron
Type: Predictive Biomarker (PRD)
Study 34919248 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34103538 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34103538 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34103538 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 36378660 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 35705139 — Biomarker: CAV1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAV1; CAV
Study 35705139 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 35870380 — Biomarker: Error related negativity
Type: Pharmacodynamic Biomarker (PDY)
Study 34806261 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 34763309 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34763309 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 36508996 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36508996 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 36508996 — Biomarker: Platelet to lymphocyte
Type: Safety Biomarker (SAF)
Study 36508996 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 33507248 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 34476450 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34476450 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33711095 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32376702 — Biomarker: HLA-DRB1
Type: Safety Biomarker (SAF)
Genes: HLA-DR1B
Study 32376702 — Biomarker: HLA-DQA1
Type: Safety Biomarker (SAF)
Genes: CELIAC1
Study 33531453 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35942813 — Biomarker: Intact parathyroid hormone
Type: Predictive Biomarker (PRD)
Study 35942813 — Biomarker: Serum calcium
Type: Surrogate Endpoint (SUR)
Study 34819261 — Biomarker: MME mRNA
Type: Predictive Biomarker (PRD)
Genes: MME; EPN
Study 35933224 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 35105177 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32023606 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 32023606 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32023606 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33731305 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 32438787 — Biomarker: RPE mRNA
Type: Predictive Biomarker (PRD)
Genes: RPE; HUSSY-17
Study 32717294 — Biomarker: 5HTT
Type: Predictive Biomarker (PRD)
Genes: SLC6A4; 5-HTT; SERT1
Study 32717294 — Biomarker: OXTR mRNA
Type: Predictive Biomarker (PRD)
Genes: OXTR
Study 33099898 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 35729493 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35273107 — Biomarker: CDA mRNA
Type: Predictive Biomarker (PRD)
Genes: CDA; CDD
Study 33038066 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35502340 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 35840747 — Biomarker: NRM mRNA
Type: Predictive Biomarker (PRD)
Genes: NRM; NRM29; UNQ555/PRO1112
Study 32107343 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35906662 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 33155236 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 36060969 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 36060969 — Biomarker: SHBG mRNA
Type: Predictive Biomarker (PRD)
Genes: SHBG
Study 34134812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34472693 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 32700461 — Biomarker: Anti-acetylcholine receptor antibody
Type: Predictive Biomarker (PRD)
Study 32369191 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32369191 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32533792 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 32533792 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 32533792 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 35768774 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36282988 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 34545949 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 34545949 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 32369571 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 36207891 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33536253 — Biomarker: Serum testosterone
Type: Surrogate Endpoint (SUR)
Study 33485162 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35643956 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 33881472 — Biomarker: FOS mRNA
Type: Predictive Biomarker (PRD)
Genes: FOS; G0S7
Study 34347775 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 35366393 — Biomarker: PRKRA mRNA
Type: Predictive Biomarker (PRD)
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 33720069 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35149701 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32090389 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 33887343 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 34302324 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 34302324 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36306479 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33507592 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33507592 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 33749762 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 36307161 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33755227 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 33755227 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 34000119 — Biomarker: PGD mRNA
Type: Predictive Biomarker (PRD)
Genes: PGD; PGDH
Study 33248586 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 36325128 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36325128 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 32959588 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 35461434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35791582 — Biomarker: Clusterin
Type: Safety Biomarker (SAF)
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 35791582 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 35791582 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 35791582 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 33047116 — Biomarker: TNFRSF11B mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11B; OCIF; OPG
Study 33249003 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 32878963 — Biomarker: ANTXR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANTXR1; ATR; TEM8
Study 33035599 — Biomarker: SAT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAT1; SAT
Study 34757657 — Biomarker: ALK tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ALK
Study 36206054 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 36206054 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32826409 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 32574722 — Biomarker: HSD3B1 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: HSD3B1; 3BH; HSDB3A
Study 34758731 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34758731 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 34942136 — Biomarker: Survival motor neuron protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 37365436 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37365436 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 32824394 — Biomarker: CPM mRNA
Type: Predictive Biomarker (PRD)
Genes: CPM
Study 32824394 — Biomarker: CNP mRNA
Type: Predictive Biomarker (PRD)
Genes: CNP
Study 37164603 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 32667286 — Biomarker: TLR8 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR8; UNQ249/PRO286
Study 35380672 — Biomarker: LPP mRNA
Type: Predictive Biomarker (PRD)
Genes: LPP
Study 32275365 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 32222857 — Biomarker: Superoxide dismutase Cu-Zn
Type: Pharmacodynamic Biomarker (PDY)
Genes: SOD1
Study 35645167 — Biomarker: Exhaled nitric oxide
Type: Predictive Biomarker (PRD)
Study 33586796 — Biomarker: SI mRNA
Type: Predictive Biomarker (PRD)
Genes: SI
Study 32086272 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 35921122 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 36353918 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 33990958 — Biomarker: Natriuretic peptides A
Type: Safety Biomarker (SAF)
Genes: NPPA; ANP; PND
Study 36548296 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33485960 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35582947 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34062937 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36341216 — Biomarker: PCSK9 mRNA
Type: Predictive Biomarker (PRD)
Genes: PCSK9; NARC1; PSEC0052
Study 36341216 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33039478 — Biomarker: Interleukin 7 receptor alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: IL7R
Study 33039478 — Biomarker: Interleukin 2 receptor alpha
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: IL2RA
Study 32977831 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 32977831 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 32164563 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 32164563 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 33221776 — Biomarker: NXF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NXF1; TAP
Study 35380713 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 34825307 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 32471770 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 33234638 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 35974369 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 32698121 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 32698121 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 36110573 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 36110573 — Biomarker: TK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TK1
Study 33075806 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 35953433 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 36347387 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 36347387 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 34433000 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 34582545 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 32657253 — Biomarker: GPR17 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPR17
Study 33082214 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 33082214 — Biomarker: CCND1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCND1; BCL1; PRAD1
Study 33082214 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33082214 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 33082214 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 33082214 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 32324130 — Biomarker: Ornithine transcarbamylase
Type: Safety Biomarker (SAF)
Genes: OTC
Study 34358343 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402