AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 38746275 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38746861 — Biomarker: CCL17 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL17; SCYA17; TARC
Study 38746861 — Biomarker: CCL26 mRNA
Type: Predictive Biomarker (PRD)
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 38746861 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 38747749 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38748319 — Biomarker: TLR7 mRNA
Type: Predictive Biomarker (PRD)
Genes: TLR7; UNQ248/PRO285
Study 38748596 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38748596 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38748596 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 38748596 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38748939 — Biomarker: BTC mRNA
Type: Predictive Biomarker (PRD)
Genes: BTC
Study 38749033 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 38750034 — Biomarker: Carcinoembryonic antigen CEA
Type: Monitoring Biomarker (MOI)
Genes: CEACAM5; CEA
Study 38750102 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 38750142 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 38750351 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 38750351 — Biomarker: BRCA2 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA2; FACD; FANCD1
Study 38751488 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38751523 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38752352 — Biomarker: PAH mRNA
Type: Predictive Biomarker (PRD)
Genes: PAH
Study 38752418 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38752577 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38752577 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 38752650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38752972 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38753174 — Biomarker: BCO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCO1; BCDO; BCDO1; BCMO1
Study 38753448 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38753813 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38754046 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 38754046 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 38754046 — Biomarker: PLCG2 mRNA
Type: Predictive Biomarker (PRD)
Genes: PLCG2
Study 38754068 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38754125 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38754459 — Biomarker: CNTNAP2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNTNAP2; CASPR2; KIAA0868
Study 38754780 — Biomarker: Pathological complete response
Type: Surrogate Endpoint (SUR)
Study 38754881 — Biomarker: ACAD8 mRNA
Type: Predictive Biomarker (PRD)
Genes: ACAD8; ARC42; IBD
Study 38754888 — Biomarker: GFAP mRNA
Type: Predictive Biomarker (PRD)
Genes: GFAP
Study 38755096 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38755201 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38755201 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 38755568 — Biomarker: miR-106b
Type: Predictive Biomarker (PRD)
Genes: MIR106B
Study 38755568 — Biomarker: miR-122
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR122
Study 38755568 — Biomarker: miR-143
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR143
Study 38755568 — Biomarker: miR-16
Type: Safety Biomarker (SAF)
Study 38755568 — Biomarker: miR-181a
Type: Safety Biomarker (SAF)
Study 38755568 — Biomarker: miR-25
Type: Predictive Biomarker (PRD)
Genes: MIR25
Study 38755568 — Biomarker: miR-485-3p
Type: Predictive Biomarker (PRD)
Genes: MIR485
Study 38755568 — Biomarker: miR-629
Type: Safety Biomarker (SAF)
Genes: MIR629
Study 38755568 — Biomarker: miR-92a-3p
Type: Monitoring Biomarker (MOI)
Study 38755568 — Biomarker: miR-34a
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: MIR34A
Study 38755585 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 38755585 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 38756107 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38756738 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38756738 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38757982 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 38758370 — Biomarker: SV2A mRNA
Type: Predictive Biomarker (PRD)
Genes: SV2A; KIAA0736; PSEC0174
Study 38758581 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38758815 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 38758815 — Biomarker: WWTR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: WWTR1; TAZ
Study 38758815 — Biomarker: MAGI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 38758815 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38758815 — Biomarker: ATG5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ATG5; APG5L; ASP
Study 38758815 — Biomarker: FADD mRNA
Type: Predictive Biomarker (PRD)
Genes: FADD; MORT1; GIG3
Study 38758815 — Biomarker: Signal transducer and activator of transcription 3
Type: Pharmacodynamic Biomarker (PDY)
Genes: STAT3; APRF
Study 38758815 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38758967 — Biomarker: MB mRNA
Type: Predictive Biomarker (PRD)
Genes: MB
Study 38759905 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 38759910 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38760029 — Biomarker: MARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MARS1; MARS
Study 38760075 — Biomarker: TPBG mRNA
Type: Predictive Biomarker (PRD)
Genes: TPBG; 5T4
Study 38760098 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 38760098 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 38760589 — Biomarker: TNFR1B
Type: Predictive Biomarker (PRD)
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 38760804 — Biomarker: Type I cytoskeletal 18 Keratin
Type: Safety Biomarker (SAF)
Genes: KRT18; CYK18; PIG46
Study 38761800 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 38761816 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38761976 — Biomarker: Myeloperoxidase
Type: Safety Biomarker (SAF)
Genes: MPO
Study 38761976 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38761976 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38761976 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38762090 — Biomarker: FH mRNA
Type: Predictive Biomarker (PRD)
Genes: FH
Study 38762090 — Biomarker: LDLR mRNA
Type: Predictive Biomarker (PRD)
Genes: LDLR
Study 38762090 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 38762348 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 38762348 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38762348 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38762353 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38762353 — Biomarker: TPI1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPI1; TPI
Study 38762522 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38762708 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 38762719 — Biomarker: Growth/differentiation factor 15
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 38762719 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 38762720 — Biomarker: BPI mRNA
Type: Predictive Biomarker (PRD)
Genes: BPI
Study 38762797 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 38763104 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38763104 — Biomarker: Proto-oncogene c-Met
Type: Predictive Biomarker (PRD)
Genes: MET
Study 38763257 — Biomarker: COMT mRNA
Type: Predictive Biomarker (PRD)
Genes: COMT
Study 38764430 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38764430 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 38764430 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38764430 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38764445 — Biomarker: Fibroblast growth factor 23
Type: Pharmacodynamic Biomarker (PDY)
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 38764445 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 38764682 — Biomarker: Aurora kinase A
Type: Predictive Biomarker (PRD)
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 38765202 — Biomarker: O-6-methylguanine-DNA-alkyltransferase
Type: Predictive Biomarker (PRD)
Genes: MGMT
Study 38766125 — Biomarker: C8G mRNA
Type: Predictive Biomarker (PRD)
Genes: C8G
Study 38766125 — Biomarker: PPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1
Study 38766125 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 38766125 — Biomarker: Interleukin 8
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CXCL8; IL8
Study 38766125 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38766126 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38766126 — Biomarker: CCND1
Type: Predictive Biomarker (PRD)
Genes: U21B31
Study 38767193 — Biomarker: PPT1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PPT1; CLN1; PPT
Study 38767196 — Biomarker: CAPS mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPS
Study 38767248 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 38767248 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 38767614 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 38767614 — Biomarker: IL4
Type: Safety Biomarker (SAF)
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 38767614 — Biomarker: Interleukin 13
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: IL13; NC30
Study 38767650 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38767650 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 38767694 — Biomarker: ABO mRNA
Type: Predictive Biomarker (PRD)
Genes: ABO
Study 38767937 — Biomarker: REL mRNA
Type: Predictive Biomarker (PRD)
Genes: REL
Study 38767985 — Biomarker: PYY mRNA
Type: Predictive Biomarker (PRD)
Genes: PYY
Study 38767985 — Biomarker: Gastric inhibitory polypeptide
Type: Pharmacodynamic Biomarker (PDY)
Genes: GIP
Study 38768299 — Biomarker: GLS mRNA
Type: Predictive Biomarker (PRD)
Genes: GLS; GLS1; KIAA0838
Study 38768428 — Biomarker: TNFRSF17 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF17; BCM; BCMA
Study 38768428 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 38769431 — Biomarker: ARC mRNA
Type: Predictive Biomarker (PRD)
Genes: ARC; KIAA0278
Study 38769543 — Biomarker: Tumor-infiltrating lymphocyte
Type: Predictive Biomarker (PRD)
Study 38769543 — Biomarker: Interleukin 2
Type: Safety Biomarker (SAF)
Genes: IL2
Study 38769643 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38769923 — Biomarker: ARCN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ARCN1; COPD
Study 38769923 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 38769974 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38770592 — Biomarker: C-X-C motif chemokine 9
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: CXCL9; CMK; MIG; SCYB9
Study 38770592 — Biomarker: C-X-C motif chemokine 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CXCL10; INP10; SCYB10
Study 38770592 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38770592 — Biomarker: Matrix metalloproteinase 3
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: MMP3; STMY1
Study 38770818 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 38770818 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 38771986 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 38771995 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38771995 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38771995 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38772935 — Biomarker: MSN mRNA
Type: Predictive Biomarker (PRD)
Genes: MSN
Study 38772998 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 38773189 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 38773224 — Biomarker: THBS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: THBS1; TSP; TSP1
Study 38773457 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 38773528 — Biomarker: Glucose-6-phosphate dehydrogenase
Type: Safety Biomarker (SAF)
Genes: G6PD
Study 38773563 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 38773563 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38773662 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38774367 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38774381 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38774484 — Biomarker: MAS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAS1; MAS
Study 38775253 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 38775255 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 38775255 — Biomarker: NLRP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 38775275 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38775302 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 38775718 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38775718 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 38775718 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 38775718 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 38775718 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 38776275 — Biomarker: Tripeptidyl-peptidase I
Type: Predictive Biomarker (PRD)
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 38776334 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38776391 — Biomarker: CLDN6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CLDN6; UNQ757/PRO1488
Study 38776484 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 38776484 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38776498 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 38777393 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38777421 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 38777939 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38778345 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38780499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38780604 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 38780927 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38780927 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38781013 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 38781564 — Biomarker: CD37 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD37; TSPAN26
Study 38781564 — Biomarker: Interleukin 18
Type: Safety Biomarker (SAF)
Genes: IL18; IGIF; IL1F4
Study 38781591 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38781664 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38781965 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38781965 — Biomarker: KRAS mRNA
Type: Predictive Biomarker (PRD)
Genes: KRAS; KRAS2; RASK2
Study 38781965 — Biomarker: Serine/threonine-protein kinase STK11
Type: Safety Biomarker (SAF)
Genes: STK11
Study 38781965 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 38781965 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 38782542 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38782549 — Biomarker: JAK1
Type: Predictive Biomarker (PRD)
Genes: JAK1A; JTK3
Study 38783176 — Biomarker: MAF mRNA
Type: Predictive Biomarker (PRD)
Genes: MAF
Study 38784916 — Biomarker: SNAP25 mRNA
Type: Predictive Biomarker (PRD)
Genes: SNAP25; SNAP
Study 38785259 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38787613 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 38788664 — Biomarker: SMPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SMPD1; ASM
Study 38788744 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38788907 — Biomarker: CYP2A6 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2A6; CYP2A3
Study 38788907 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 38788907 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 38788907 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 38789460 — Biomarker: TIGIT mRNA
Type: Predictive Biomarker (PRD)
Genes: TIGIT; VSIG9; VSTM3
Study 38789635 — Biomarker: Cyclic guanosine monophosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 38789635 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 38789848 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 38789924 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38789924 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 38789992 — Biomarker: MSC mRNA
Type: Predictive Biomarker (PRD)
Genes: MSC; ABF1; BHLHA22
Study 38790057 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38793748 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 38794639 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 38794639 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 38794892 — Biomarker: CD38 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD38
Study 38795650 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 38795703 — Biomarker: TAPBP mRNA
Type: Predictive Biomarker (PRD)
Genes: TAPBP; NGS17; TAPA
Study 38795747 — Biomarker: FURIN mRNA
Type: Predictive Biomarker (PRD)
Genes: FURIN; FUR; PACE; PCSK3
Study 38795859 — Biomarker: TG mRNA
Type: Predictive Biomarker (PRD)
Genes: TG
Study 38795859 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38796193 — Biomarker: BCL6 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 38796193 — Biomarker: CXCL13 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCL13; BCA1; BLC; SCYB13
Study 38796193 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38796193 — Biomarker: ICOS mRNA
Type: Predictive Biomarker (PRD)
Genes: ICOS; AILIM
Study 38796326 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 38796422 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38796619 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 38796655 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 38796655 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 38797190 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 38797460 — Biomarker: RHD mRNA
Type: Predictive Biomarker (PRD)
Genes: RHD
Study 38797482 — Biomarker: BCO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BCO1; BCDO; BCDO1; BCMO1