AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 37878497 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37878624 — Biomarker: CXCR4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CXCR4
Study 37878624 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37878624 — Biomarker: Stromal cell-derived factor 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 37879047 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37879393 — Biomarker: FTCD mRNA
Type: Predictive Biomarker (PRD)
Genes: FTCD
Study 37879536 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37879536 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37879695 — Biomarker: SSTR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SSTR2
Study 37879886 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 37880076 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37880303 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37880499 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37880581 — Biomarker: FMN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FMN1; FMN; LD
Study 37880682 — Biomarker: MMRN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 37880704 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37880931 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37881307 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37881306 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 37882432 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37882668 — Biomarker: MYC mRNA
Type: Predictive Biomarker (PRD)
Genes: MYC; BHLHE39
Study 37882668 — Biomarker: Apoptosis regulator Bcl-2
Type: Predictive Biomarker (PRD)
Genes: BCL2
Study 37882668 — Biomarker: Induced myeloid leukemia cell differentiation protein Mcl-1
Type: Predictive Biomarker (PRD)
Genes: MCL1; BCL2L3
Study 37882668 — Biomarker: TP53RK mRNA
Type: Predictive Biomarker (PRD)
Genes: TP53RK; C20orf64; PRPK
Study 37882706 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37882974 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37883003 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 37883003 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37883059 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37883073 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 37883723 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37883723 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37883723 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 37883727 — Biomarker: CD22 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD22; SIGLEC2
Study 37883795 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37883795 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37883795 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37883784 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37883803 — Biomarker: SCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SCD; FADS5; SCD1; SCDOS
Study 37884063 — Biomarker: CP mRNA
Type: Predictive Biomarker (PRD)
Genes: CP
Study 37884680 — Biomarker: FTO mRNA
Type: Predictive Biomarker (PRD)
Genes: FTO; KIAA1752
Study 37885041 — Biomarker: WNT10A mRNA
Type: Predictive Biomarker (PRD)
Genes: WNT10A
Study 37885041 — Biomarker: GATA3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GATA3
Study 37885482 — Biomarker: HAL mRNA
Type: Predictive Biomarker (PRD)
Genes: HAL; HIS
Study 37885795 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37885796 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37886601 — Biomarker: CAPN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: CAPN3; CANP3; CANPL3; NCL1
Study 37886601 — Biomarker: ANO5 mRNA
Type: Predictive Biomarker (PRD)
Genes: ANO5; GDD1; TMEM16E
Study 37886601 — Biomarker: DYSF mRNA
Type: Predictive Biomarker (PRD)
Genes: DYSF; FER1L1
Study 37886601 — Biomarker: DNAJB6 mRNA
Type: Predictive Biomarker (PRD)
Genes: DNAJB6; HSJ2; MRJ; MSJ1
Study 37886601 — Biomarker: SGCA mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCA; ADL; DAG2
Study 37886601 — Biomarker: SGCB mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCB
Study 37886601 — Biomarker: SGCD mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCD
Study 37886601 — Biomarker: SGCG mRNA
Type: Predictive Biomarker (PRD)
Genes: SGCG
Study 37886601 — Biomarker: FKRP mRNA
Type: Predictive Biomarker (PRD)
Genes: FKRP
Study 37886645 — Biomarker: POMC
Type: Predictive Biomarker (PRD)
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 37886880 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37887530 — Biomarker: SLN mRNA
Type: Predictive Biomarker (PRD)
Genes: SLN
Study 37887871 — Biomarker: TCP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TCP1; CCT1; CCTA
Study 37889107 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37889298 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37889298 — Biomarker: VPS39 mRNA
Type: Predictive Biomarker (PRD)
Genes: VPS39; KIAA0770; TLP; VAM6
Study 37889298 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 37889308 — Biomarker: von Willebrand factor
Type: Safety Biomarker (SAF)
Genes: VWF; F8VWF
Study 37889308 — Biomarker: Forced vital capacity
Type: Surrogate Endpoint (SUR)
Study 37889382 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 37889382 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 37889382 — Biomarker: Fibroblast growth factor receptor
Type: Pharmacodynamic Biomarker (PDY)
Study 37889382 — Biomarker: Serum phosphate
Type: Pharmacodynamic Biomarker (PDY)
Study 37889487 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37890035 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37890143 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37890351 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37890351 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37890671 — Biomarker: SLC40A1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 37890839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37890839 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37891072 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 37891072 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37891146 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37891226 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37891549 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 37891608 — Biomarker: MZB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 37891608 — Biomarker: PIK3CA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PI3K
Study 37891608 — Biomarker: 5'-AMP-activated protein kinase subunit beta-1
Type: Pharmacodynamic Biomarker (PDY)
Genes: PRKAB1; AMPK
Study 37892656 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37893050 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37893050 — Biomarker: Procalcitonin
Type: Monitoring Biomarker (MOI)
Study 37894732 — Biomarker: ULK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ULK1; KIAA0722
Study 37895218 — Biomarker: OMD mRNA
Type: Predictive Biomarker (PRD)
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 37896812 — Biomarker: D-dimer
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Study 37897452 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 37897866 — Biomarker: FGFR3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR3; JTK4
Study 37897866 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 37898184 — Biomarker: SRL mRNA
Type: Predictive Biomarker (PRD)
Genes: SRL
Study 37898410 — Biomarker: CS mRNA
Type: Predictive Biomarker (PRD)
Genes: CS
Study 37898410 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37898410 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37898434 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37898434 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37898434 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 37899145 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 37899297 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 37899477 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37899477 — Biomarker: EPX mRNA
Type: Predictive Biomarker (PRD)
Genes: EPX; EPER; EPO; EPP
Study 37900149 — Biomarker: Serum uric acid
Type: Surrogate Endpoint (SUR)
Study 37901478 — Biomarker: CGA mRNA
Type: Predictive Biomarker (PRD)
Genes: CGA
Study 37902726 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37902733 — Biomarker: LAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: LAD1; LAD
Study 37902819 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37902861 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37902861 — Biomarker: NPEPPS mRNA
Type: Predictive Biomarker (PRD)
Genes: NPEPPS; PSA
Study 37903324 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37903325 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37903465 — Biomarker: Serum luteinizing hormone
Type: Surrogate Endpoint (SUR)
Study 37903483 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37903504 — Biomarker: Circulating tumor DNA
Type: Monitoring Biomarker (MOI)
Study 37903590 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37903607 — Biomarker: SMS mRNA
Type: Predictive Biomarker (PRD)
Genes: SMS
Study 37903607 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37903679 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37903861 — Biomarker: COX2 mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: PTGS2; COX2
Study 37903899 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37903899 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37903899 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37905704 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 37905734 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37905734 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37906406 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37906649 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37906649 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37906649 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37907210 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37907305 — Biomarker: PTS mRNA
Type: Predictive Biomarker (PRD)
Genes: PTS
Study 37908359 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37909020 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37909020 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 37914483 — Biomarker: CD70 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 37914594 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37914804 — Biomarker: NLRP3 mRNA
Type: Predictive Biomarker (PRD)
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 37914804 — Biomarker: Interleukin 1 beta
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL1B; IL1F2
Study 37914804 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 37914976 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37915546 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 37915938 — Biomarker: Huntingtin
Type: Pharmacodynamic Biomarker (PDY)
Genes: HTT; HD; IT15
Study 37916028 — Biomarker: LBP mRNA
Type: Predictive Biomarker (PRD)
Genes: LBP
Study 37916028 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37916028 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37916266 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37916266 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37916517 — Biomarker: TTR mRNA
Type: Predictive Biomarker (PRD)
Genes: TTR; PALB
Study 37916517 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37916620 — Biomarker: TNFSF13 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 37916745 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37916926 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37916926 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37917058 — Biomarker: POLE mRNA
Type: Predictive Biomarker (PRD)
Genes: POLE; POLE1
Study 37917058 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 37917063 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37917187 — Biomarker: IDH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: IDH1; PICD
Study 37917187 — Biomarker: 2-hydroxyglutarate
Type: Pharmacodynamic Biomarker (PDY)
Study 37918066 — Biomarker: CAT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CAT
Study 37918404 — Biomarker: SLC25A21 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC25A21; ODC
Study 37918675 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37918933 — Biomarker: STS mRNA
Type: Predictive Biomarker (PRD)
Genes: STS; ARSC1
Study 37919456 — Biomarker: Plasma DNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37919742 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37919791 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 37919816 — Biomarker: Serum albumin
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37920921 — Biomarker: CYP3A5 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A5
Study 37921755 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37921755 — Biomarker: GNRH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GNRH1; GNRH; GRH; LHRH
Study 37921755 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 37921769 — Biomarker: DCC mRNA
Type: Predictive Biomarker (PRD)
Genes: DCC; IGDCC1
Study 37921846 — Biomarker: REST mRNA
Type: Predictive Biomarker (PRD)
Genes: REST; NRSF; XBR
Study 37922035 — Biomarker: SRCIN1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 37922035 — Biomarker: ROS1
Type: Predictive Biomarker (PRD)
Genes: MCF3; ROS; c-ros-1
Study 37922035 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 37922035 — Biomarker: Reactive oxygen species
Type: Safety Biomarker (SAF)
Study 37922035 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 37922438 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37922692 — Biomarker: PIK3CA mRNA
Type: Predictive Biomarker (PRD)
Genes: PIK3CA
Study 37922692 — Biomarker: FGFR2 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR2; BEK; KGFR; KSAM
Study 37922692 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37922692 — Biomarker: Tumor mutational burden
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37922692 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 37922930 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37922989 — Biomarker: Leukocyte surface antigen Leu-16
Type: Predictive Biomarker (PRD)
Genes: MS4A1; CD20
Study 37922989 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37924084 — Biomarker: PC mRNA
Type: Predictive Biomarker (PRD)
Genes: PC
Study 37924154 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37926085 — Biomarker: RAPGEF5 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 37926336 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 37928434 — Biomarker: MAP3K1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MAP3K1; MAPKKK1; MEKK; MEKK1
Study 37928434 — Biomarker: miR-320b
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37928895 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37928922 — Biomarker: CAMP mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMP; CAP18; FALL39; HSD26
Study 37929602 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37929602 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37929840 — Biomarker: PDE5A mRNA
Type: Predictive Biomarker (PRD)
Genes: PDE5A; PDE5
Study 37929952 — Biomarker: NUCB1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NUCB1; NUC
Study 37930156 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37930781 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 37931445 — Biomarker: ASCL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ASCL1; ASH1; BHLHA46; HASH1
Study 37931445 — Biomarker: NEUROD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NEUROD1; BHLHA3; NEUROD
Study 37931445 — Biomarker: POU2F3 mRNA
Type: Predictive Biomarker (PRD)
Genes: POU2F3; OTF11; PLA1
Study 37931480 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 37931480 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 37931481 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37931629 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 37932009 — Biomarker: Tyrosine-protein kinase BTK
Type: Pharmacodynamic Biomarker (PDY)
Genes: BTK; AGMX1; ATK; BPK
Study 37932258 — Biomarker: AOC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: AOC3; VAP1
Study 37932443 — Biomarker: SLC35A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC35A2; UGALT; UGT; UGTL
Study 37932648 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 37932650 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37932961 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37932961 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 37933882 — Biomarker: EFS mRNA
Type: Predictive Biomarker (PRD)
Genes: EFS; CASS3
Study 37934000 — Biomarker: RET mRNA
Type: Predictive Biomarker (PRD)
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 37934000 — Biomarker: FGFR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 37934000 — Biomarker: Tropomyosin-related kinase A
Type: Pharmacodynamic Biomarker (PDY)
Genes: NTRK1; MTC; TRK; TRKA
Study 37934948 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 37935477 — Biomarker: GAD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: GAD1; GAD; GAD67
Study 37935564 — Biomarker: CD46 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD46; MCP; MIC10
Study 37935564 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 37935631 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37935631 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 37935631 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37935839 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37935839 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1