AIM-Harvard/TrialPanorama-filtered huggingface dataset:
Study 37428653 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37429637 — Biomarker: B-type natriuretic peptide
Type: Safety Biomarker (SAF)
Genes: NPPB
Study 37429637 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37429923 — Biomarker: TBXT mRNA
Type: Predictive Biomarker (PRD)
Genes: TBXT; T
Study 37430233 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37430359 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37430546 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37431558 — Biomarker: FEV mRNA
Type: Predictive Biomarker (PRD)
Genes: FEV; PET1
Study 37431838 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37431838 — Biomarker: Matrix metalloproteinase 9
Type: Pharmacodynamic Biomarker (PDY)
Genes: MMP9; CLG4B
Study 37432736 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37432736 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 37432736 — Biomarker: Forkhead box protein P3
Type: Predictive Biomarker (PRD)
Genes: FOXP3; IPEX; JM2
Study 37432736 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37432736 — Biomarker: KLRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 37432736 — Biomarker: PDCD1
Type: Safety Biomarker (SAF)
Genes: CD279; PD1; hSLE1; PD-1
Study 37432736 — Biomarker: EOMES mRNA
Type: Predictive Biomarker (PRD)
Genes: EOMES; TBR2
Study 37433173 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37433173 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37433436 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37433436 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37433436 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37433698 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37433698 — Biomarker: High density lipoprotein cholesterol
Type: Pharmacodynamic Biomarker (PDY)
Study 37433698 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37433734 — Biomarker: TKTL1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TKTL1; TKR; TKT2
Study 37433788 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37434027 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37434027 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 37434165 — Biomarker: SP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: SP4
Study 37434306 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37434306 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37435073 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37435938 — Biomarker: Dipeptidyl peptidase 4
Type: Pharmacodynamic Biomarker (PDY)
Genes: DPP4; ADCP2; CD26
Study 37437694 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37438071 — Biomarker: SPDEF mRNA
Type: Predictive Biomarker (PRD)
Genes: SPDEF; PDEF; PSE
Study 37438197 — Biomarker: CFTR mRNA
Type: Predictive Biomarker (PRD)
Genes: CFTR; ABCC7
Study 37438722 — Biomarker: SERPINA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 37438734 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 37438734 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37438741 — Biomarker: Mitochondrial DNA
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37438853 — Biomarker: SLC5A2 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A2; SGLT2
Study 37438853 — Biomarker: GATA-type zinc finger protein 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: ZGLP1; GLP1
Study 37438853 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37439373 — Biomarker: MBTPS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 37439373 — Biomarker: Free fatty acids
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37439701 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37440099 — Biomarker: NF1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF1
Study 37440099 — Biomarker: NF2 mRNA
Type: Predictive Biomarker (PRD)
Genes: NF2; SCH
Study 37440217 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 37440239 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37440239 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 37440239 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 37441104 — Biomarker: Complement C5
Type: Pharmacodynamic Biomarker (PDY)
Genes: C5; CPAMD4
Study 37441104 — Biomarker: AQP4 mRNA
Type: Predictive Biomarker (PRD)
Genes: AQP4
Study 37441546 — Biomarker: Hyaluronic acid
Type: Safety Biomarker (SAF)
Study 37442152 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 37442748 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37442917 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37442917 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 37443083 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37443452 — Biomarker: Thyroid stimulating hormone
Type: Safety Biomarker (SAF)
Study 37443809 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37444406 — Biomarker: PAFAH1B1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 37444551 — Biomarker: RANGAP1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RANGAP1; KIAA1835; SD
Study 37449424 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37449424 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37449568 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37449573 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37449658 — Biomarker: TNFRSF11A mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFRSF11A; RANK
Study 37449716 — Biomarker: Epidermal growth factor
Type: Monitoring Biomarker (MOI)
Genes: EGF
Study 37450351 — Biomarker: DIABLO mRNA
Type: Predictive Biomarker (PRD)
Genes: DIABLO; SMAC
Study 37450351 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37450351 — Biomarker: MFSD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: MFSD11; ET
Study 37450351 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37450351 — Biomarker: Interferon gamma
Type: Safety Biomarker (SAF); Monitoring Biomarker (MOI)
Genes: IFNG
Study 37451295 — Biomarker: MCC mRNA
Type: Predictive Biomarker (PRD)
Genes: MCC
Study 37451297 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37451695 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 37451877 — Biomarker: TMPRSS11D mRNA
Type: Predictive Biomarker (PRD)
Genes: TMPRSS11D; HAT
Study 37451930 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37451930 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37452151 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37452174 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37452279 — Biomarker: Transmembrane glycoprotein NMB
Type: Pharmacodynamic Biomarker (PDY)
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 37452341 — Biomarker: Placenta growth factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Genes: PGF; PGFL; PLGF
Study 37452374 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 37452707 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37452707 — Biomarker: Interleukin 1
Type: Safety Biomarker (SAF)
Study 37452707 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37452849 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37453736 — Biomarker: PON1 mRNA
Type: Predictive Biomarker (PRD)
Genes: PON1; PON
Study 37453737 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37454014 — Biomarker: Ki-67
Type: Predictive Biomarker (PRD)
Genes: MKI67; MIB-1; PPP1R105
Study 37455345 — Biomarker: TET2 mRNA
Type: Predictive Biomarker (PRD)
Genes: TET2; KIAA1546; Nbla00191
Study 37455345 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37455345 — Biomarker: JAK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK2
Study 37455345 — Biomarker: PTPN11 mRNA
Type: Predictive Biomarker (PRD)
Genes: PTPN11; PTP2C; SHPTP2
Study 37455345 — Biomarker: RUNX1 mRNA
Type: Predictive Biomarker (PRD)
Genes: RUNX1; AML1; CBFA2
Study 37455588 — Biomarker: JAK3 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK3
Study 37456358 — Biomarker: Multidrug resistance protein 1
Type: Predictive Biomarker (PRD)
Genes: ABCB1; MDR1; PGY1
Study 37456507 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37457622 — Biomarker: Serum creatinine
Type: Surrogate Endpoint (SUR)
Study 37457966 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37458272 — Biomarker: Amyloid beta peptide (1-40)
Type: Pharmacodynamic Biomarker (PDY)
Genes: APP; A4; AD1
Study 37458583 — Biomarker: HBV DNA
Type: Monitoring Biomarker (MOI)
Study 37459141 — Biomarker: Microtubule-associated protein tau
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37459153 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37459248 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37459335 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37459335 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37459335 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37460024 — Biomarker: SLC5A8 mRNA
Type: Predictive Biomarker (PRD)
Genes: SLC5A8; AIT; SMCT; SMCT1
Study 37460603 — Biomarker: Synuclein alpha
Type: Pharmacodynamic Biomarker (PDY)
Genes: SNCA; NACP; PARK1
Study 37460683 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37460683 — Biomarker: Epidermal growth factor receptor
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: EGFR; ERBB; ERBB1; HER1
Study 37460683 — Biomarker: ERBB3 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB3; HER3
Study 37460683 — Biomarker: ERBB4 mRNA
Type: Predictive Biomarker (PRD)
Genes: ERBB4; HER4
Study 37460782 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 37461034 — Biomarker: CHM mRNA
Type: Predictive Biomarker (PRD)
Genes: CHM; REP1; TCD
Study 37461089 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37461207 — Biomarker: CD4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD4
Study 37461659 — Biomarker: Transforming growth factor beta 1
Type: Safety Biomarker (SAF)
Genes: TGFB1; TGFB
Study 37461954 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37461987 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37462430 — Biomarker: PVR mRNA
Type: Predictive Biomarker (PRD)
Genes: PVR; PVS
Study 37462430 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37462430 — Biomarker: Pulmonary vascular resistance
Type: Surrogate Endpoint (SUR)
Study 37462798 — Biomarker: AFP mRNA
Type: Predictive Biomarker (PRD)
Genes: AFP; HPAFP
Study 37463054 — Biomarker: Vitamin D-binding protein
Type: Predictive Biomarker (PRD)
Genes: GC
Study 37463054 — Biomarker: Complete renal response
Type: Surrogate Endpoint (SUR)
Study 37463058 — Biomarker: Granulocyte-macrophage colony-stimulating factor
Type: Safety Biomarker (SAF)
Genes: CSF2; GMCSF
Study 37464355 — Biomarker: DES mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: DES
Study 37464378 — Biomarker: Vascular endothelial growth factor A
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: VEGFA; VEGF
Study 37464378 — Biomarker: Microsatellite instability
Type: Predictive Biomarker (PRD)
Study 37464378 — Biomarker: Vascular endothelial growth factor
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY)
Study 37464390 — Biomarker: SLC6A3
Type: Safety Biomarker (SAF)
Genes: DAT
Study 37464448 — Biomarker: EBPL mRNA
Type: Predictive Biomarker (PRD)
Genes: EBPL; EBRP; ERP
Study 37464978 — Biomarker: CYP3A4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP3A4; CYP3A3
Study 37464978 — Biomarker: CYP2C9 mRNA
Type: Predictive Biomarker (PRD)
Genes: CYP2C9; CYP2C10
Study 37464978 — Biomarker: Cytochrome P450 2C19
Type: Safety Biomarker (SAF)
Genes: CYP2C19
Study 37466151 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37466221 — Biomarker: Neutralizing antibody
Type: Surrogate Endpoint (SUR)
Study 37467213 — Biomarker: IGFALS mRNA
Type: Predictive Biomarker (PRD)
Genes: IGFALS; ALS
Study 37467318 — Biomarker: FOXO1 mRNA
Type: Predictive Biomarker (PRD)
Genes: FOXO1; FKHR; FOXO1A
Study 37467318 — Biomarker: GDA mRNA
Type: Predictive Biomarker (PRD)
Genes: GDA; KIAA1258
Study 37467452 — Biomarker: RAD51 mRNA
Type: Predictive Biomarker (PRD)
Genes: RAD51; RAD51A; RECA
Study 37467452 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 37467458 — Biomarker: Cell-free DNA
Type: Monitoring Biomarker (MOI)
Study 37467498 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37467930 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37468185 — Biomarker: INVS mRNA
Type: Predictive Biomarker (PRD)
Genes: INVS; INV; NPHP2
Study 37468836 — Biomarker: CAMLG mRNA
Type: Predictive Biomarker (PRD)
Genes: CAMLG; CAML; GET2
Study 37468836 — Biomarker: GALNT2 mRNA
Type: Predictive Biomarker (PRD)
Genes: GALNT2
Study 37468836 — Biomarker: SPINDOC mRNA
Type: Predictive Biomarker (PRD)
Genes: SPINDOC; C11orf84
Study 37468836 — Biomarker: THOC5 mRNA
Type: Predictive Biomarker (PRD)
Genes: THOC5; C22orf19; KIAA0983
Study 37468836 — Biomarker: SAMD11 mRNA
Type: Predictive Biomarker (PRD)
Genes: SAMD11
Study 37468890 — Biomarker: DMD mRNA
Type: Predictive Biomarker (PRD)
Genes: DMD
Study 37468918 — Biomarker: RCN3 mRNA
Type: Predictive Biomarker (PRD)
Genes: RCN3; UNQ239/PRO272
Study 37468918 — Biomarker: FSTL3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FSTL3; FLRG; UNQ674/PRO1308
Study 37468918 — Biomarker: SCRG1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SCRG1; UNQ390/PRO725
Study 37468918 — Biomarker: NPDC1 mRNA
Type: Predictive Biomarker (PRD)
Genes: NPDC1
Study 37468918 — Biomarker: Apolipoprotein E
Type: Predictive Biomarker (PRD)
Genes: APOE
Study 37468918 — Biomarker: Cystatin C
Type: Safety Biomarker (SAF)
Genes: CST3
Study 37468978 — Biomarker: BDNF mRNA
Type: Predictive Biomarker (PRD); Monitoring Biomarker (MOI)
Genes: BDNF
Study 37468978 — Biomarker: BDNF
Type: Safety Biomarker (SAF)
Study 37470057 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 37470295 — Biomarker: Nerve growth factor
Type: Predictive Biomarker (PRD)
Genes: NGF; NGFB
Study 37470445 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37470772 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37471135 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37473964 — Biomarker: SARS1 mRNA
Type: Predictive Biomarker (PRD)
Genes: SARS1; SARS; SERS
Study 37474180 — Biomarker: TNFSF10 mRNA
Type: Predictive Biomarker (PRD)
Genes: TNFSF10; APO2L; TRAIL
Study 37474184 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37474184 — Biomarker: Interleukin 6
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL6; IFNB2
Study 37474720 — Biomarker: BRCA1 mRNA
Type: Predictive Biomarker (PRD)
Genes: BRCA1; RNF53
Study 37474720 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 37474729 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37474729 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1
Study 37474784 — Biomarker: GPT mRNA
Type: Predictive Biomarker (PRD)
Genes: GPT; AAT1; GPT1
Study 37474829 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37474971 — Biomarker: Bacteroidetes phylum
Type: Safety Biomarker (SAF)
Study 37475004 — Biomarker: HR mRNA
Type: Predictive Biomarker (PRD)
Genes: HR
Study 37475004 — Biomarker: Erbb2 tyrosine kinase receptor
Type: Predictive Biomarker (PRD)
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37475004 — Biomarker: CDK4 mRNA
Type: Predictive Biomarker (PRD)
Genes: CDK4
Study 37475004 — Biomarker: Cellular tumor antigen p53
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: TP53; P53
Study 37475004 — Biomarker: Retinoblastoma-associated protein
Type: Pharmacodynamic Biomarker (PDY)
Genes: RB1
Study 37475004 — Biomarker: Estrogen receptor
Type: Predictive Biomarker (PRD)
Genes: ESR1; ESR; NR3A1
Study 37475004 — Biomarker: Phosphatase and tensin homolog
Type: Predictive Biomarker (PRD)
Genes: PTEN; MMAC1; TEP1
Study 37475004 — Biomarker: KMT2C mRNA
Type: Predictive Biomarker (PRD)
Genes: KMT2C; HALR; KIAA1506; MLL3
Study 37475004 — Biomarker: Hormone receptor
Type: Predictive Biomarker (PRD)
Study 37475033 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37475033 — Biomarker: Bone mineral density
Type: Surrogate Endpoint (SUR)
Study 37475689 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37476372 — Biomarker: Lactate dehydrogenase
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37476372 — Biomarker: C-reactive protein
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: CRP; PTX1
Study 37477106 — Biomarker: Homologous recombination deficiency
Type: Predictive Biomarker (PRD)
Study 37478283 — Biomarker: GPC3 mRNA
Type: Predictive Biomarker (PRD)
Genes: GPC3; OCI5
Study 37478401 — Biomarker: CD34 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD34
Study 37478401 — Biomarker: Interleukin 10
Type: Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: IL10
Study 37479372 — Biomarker: Lysosomal acid glucosylceramidase
Type: Pharmacodynamic Biomarker (PDY)
Genes: GBA1; GBA; GC; GLUC
Study 37479483 — Biomarker: Programmed cell death 1 ligand 1
Type: Predictive Biomarker (PRD)
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37479812 — Biomarker: Blood pressure
Type: Surrogate Endpoint (SUR)
Study 37479853 — Biomarker: TPH1 mRNA
Type: Predictive Biomarker (PRD)
Genes: TPH1; TPH; TPRH; TRPH
Study 37479853 — Biomarker: DDC mRNA
Type: Predictive Biomarker (PRD)
Genes: DDC; AADC
Study 37480005 — Biomarker: CD14 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD14
Study 37480005 — Biomarker: CCR2 mRNA
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY)
Genes: CCR2; CMKBR2
Study 37480005 — Biomarker: CD40 mRNA
Type: Predictive Biomarker (PRD)
Genes: CD40; TNFRSF5
Study 37480005 — Biomarker: T-lymphocyte activation antigen CD86
Type: Pharmacodynamic Biomarker (PDY)
Genes: CD86; CD28LG2
Study 37480005 — Biomarker: Hemoglobin scavenger receptor
Type: Safety Biomarker (SAF)
Genes: CD163; M130
Study 37480005 — Biomarker: CX3CR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CX3CR1; CMKBRL1; GPR13
Study 37480164 — Biomarker: FLT3 mRNA
Type: Predictive Biomarker (PRD)
Genes: FLT3; CD135; FLK2; STK1
Study 37480164 — Biomarker: Myeloid cell surface antigen CD33
Type: Predictive Biomarker (PRD)
Genes: CD33; SIGLEC3
Study 37480391 — Biomarker: Cardiac troponin I
Type: Safety Biomarker (SAF)
Genes: TNNI3; TNNC1
Study 37480520 — Biomarker: Tumor necrosis factor
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: TNF; TNFA; TNFSF2
Study 37481477 — Biomarker: CHEK2 mRNA
Type: Predictive Biomarker (PRD)
Genes: CHEK2; CDS1; CHK2; RAD53
Study 37481477 — Biomarker: MUTYH mRNA
Type: Predictive Biomarker (PRD)
Genes: MUTYH; MYH
Study 37481608 — Biomarker: B-lymphocyte surface antigen B4
Type: Predictive Biomarker (PRD)
Genes: CD19
Study 37481608 — Biomarker: CARTPT mRNA
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Genes: CARTPT; CART
Study 37481608 — Biomarker: ENTPD1 mRNA
Type: Predictive Biomarker (PRD)
Genes: ENTPD1; CD39
Study 37481816 — Biomarker: Angiotensin-converting enzyme
Type: Pharmacodynamic Biomarker (PDY)
Genes: ACE; DCP; DCP1
Study 37482172 — Biomarker: Fatty acid amide hydrolase 1
Type: Pharmacodynamic Biomarker (PDY)
Genes: FAAH; FAAH1
Study 37482172 — Biomarker: CNR1 mRNA
Type: Predictive Biomarker (PRD)
Genes: CNR1; CNR
Study 37482217 — Biomarker: Low-density lipoprotein
Type: Pharmacodynamic Biomarker (PDY)
Study 37482512 — Biomarker: Glutamate carboxypeptidase II
Type: Predictive Biomarker (PRD)
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37482564 — Biomarker: JAK1 mRNA
Type: Predictive Biomarker (PRD)
Genes: JAK1; JAK1A; JAK1B
Study 37482646 — Biomarker: White blood cell
Type: Predictive Biomarker (PRD); Safety Biomarker (SAF)
Study 37482646 — Biomarker: Neutrophil to lymphocyte
Type: Safety Biomarker (SAF)
Study 37482878 — Biomarker: Probing pocket depth
Type: Surrogate Endpoint (SUR)
Study 37483161 — Biomarker: Complement C3
Type: Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI)
Genes: C3; CPAMD1