Patent ID: 9566251
Date: 2017-02-14
CPC Classifications: A61K,A61P

Claim:
1. A method of reducing pain in a subject in need thereof, the method comprising topically administering to the skin of the subject a composition comprising a solvent and a volatile anesthetic in an amount effective to reduce pain, wherein: (i) the solvent is at least one selected from the group consisting of dimethylsulfoxide, dimethylformamide, dimethylacetamide, N-methyl-2-pyrollidone, dimethylisosorbide, ethanol, propanol and isopropanol, (ii) the solvent is present in an amount effective to reduce the vapor pressure of the volatile anesthetic, (iii) the volatile anesthetic is in an emulsion, a liposome suspension, or a microdroplet suspension, (iv) the volatile anesthetic is at least one selected from the group consisting of isoflurane, halothane, enflurane, sevoflurane, desflurane and methoxyflurane, and (v) administration of the volatile anesthetic to the skin of the subject reduces pain in the subject.