Patent ID: 9643174
Date: 2017-05-09
CPC Classifications: B01J,C07K,C08F

Claim:
1. A temperature responsive adsorbent capable of separating a physiologically active substance comprising a copolymer containing at least N-isopropylacrylamide immobilized to a support material surface, wherein at least a portion of monomer units of the copolymer has a sulfonic acid group, and the sulfonic acid group is introduced into the copolymer by polymerizing monomer compositions by a surface graft polymerization method to form the copolymer, each of the monomer compositions containing a monomer having the sulfonic acid group and/or a precursor monomer for introducing the sulfonic acid group in a ratio of 0.01 to 5 mol % relative to the N-isopropylacrylamide, wherein at least a portion of the monomer units of the copolymer having the sulfonic acid group is an acrylic acid derivative or a methacrylic acid derivative and has a group represented by the following chemical formula (4) or (5):