Patent ID: 9717762
Date: 2017-08-01
CPC Classifications: A61K,C12N,G01N

Claim:
1. A method for determining atrial and/or ventricular cardiomyocytes in a sample comprising cardiomyocytes, the method comprising the steps: a) contacting said sample: b) contacting said sample with an agent that is distinguishably distinct from the antigen binding moieties used in step (a), whereby the agent specifically labels cardiomyocytes in the sample, c) determining atrial and/or ventricular cardiomyocytes in the sample by detecting and comparing the intensity of labeling of cells in the sample for the CD49e antigen and/or the CD49f antigen with the intensity of labeling of the same cells by the agent, wherein ventricular cardiomyocytes are determined as being labeled with the agent and having more intense labeling of CD49e and/or less intense labeling of CD49f; and/or atrial cardiomyocytes are determined as being labeled with the agent and having more intense labeling of CD49f and/or less intense labeling of CD49e.