Patent ID: 9645144
Date: 2017-05-09
CPC Classifications: G01N,G01Q

Claim:
1. A biomolecular measurement apparatus, which enables to measure the intermolecular forces arising from the interaction between two biomolecules or the intramolecular forces of a single biomolecule by using an atomic force microscope, comprising: at least one cantilever which remains fixed; at least one cantilever tip to which the single biomolecule can bind; at least one magnetic nanowire to the end of which the single biomolecule can bind; the single molecule which can hind to the end of the magnetic nanowire can bind to an other biomolecule which can bind to the cantilever tip or to the cantilever tip so that the two biomolecules bound together or the single biomolecule can be located between the magnetic nanowire and the cantilever tip, wherein the cantilever tip is pointed and has a radius of curvature at an apex of the cantilever tip that allows binding of only a single biomolecule; at least one laser source which projects light on the cantilever; at least one photodetector on which the light reflected from the cantilever is projected; at least one actuator which, by applying magnetic force to the magnetic nanowire, enables to pull and push the magnetic nanowire on x, y, z axes, wherein, the magnetic nanowire moves by means of the magnetic force exerted by the actuator and enables to move the single biomolecule or the two biomolecules attached to the end of the magnetic nanowire; and the cantilever makes a movement at any coordinate on the x, y and z axes in the direction of the single biomolecule or the two biomolecules without using any actuator, only by means of the movement of the single biomolecule or the two biomolecules actuated by the actuator, wherein the end of the magnetic nanowire that is the area of attachment for the single biomolecule or one of the two biomolecules is produced from gold or polymer, and other parts of the magnetic nanowire are made of a magnetic material which does not bind to the single biomolecule.