Patent ID: 9562113
Date: 2017-02-07
CPC Classifications: A61K,C07B,C07D,C07F,C08B

Claim:
1. An alginate conjugate having the formula: wherein X is —(CH L is a linker selected from the group consisting of: wherein n, n′ and n″ are each independently a number from 0 to 10; Alg is alginic acid or an alginate salt; and Y is a spacer directly attached to the reducing end unit of alginate or the carboxyl groups of the alginate polymer chain via the active nitrogen, and has the following structure: wherein R is selected from the group consisting of hydrogen, alkyl, benzyl or an aromatic group; or a pharmaceutically acceptable salt or solvate thereof; and, wherein the alginate conjugate comprises a metal ion chelated by the 1,4,7-triazacyclononane-1,4,7-triacetic acid moiety.