Patent ID: 9539324
Date: 2017-01-10
CPC Classifications: A61K,C07K

Claim:
1. A method of treating pain in an individual, comprising administering a therapeutically effective amount of a humanized anti-human NGF Fab, Fab′, Fv or scFv antibody fragment (i) having binding specificity for NGF that does not substantially increase the inflammatory response of a patient following administration of said humanized Fab, Fab′, Fv or scFv antibody fragment and (ii) comprising the variable light (V 1 ) chain complementarity determining regions (CDRs) of SEQ ID NO: 45; SEQ ID NO: 46; and SEQ ID NO: 47 and the variable heavy (V 11 ) chain CDRs of SEQ ID NO: 48; SEQ ID NO: 49; and SEQ ID NO: 50.