Patent ID: 9533012
Date: 2017-01-03
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method for enhancing the therapeutic effect of a stem cell on digestive diseases, hepatic diseases, renal diseases, neurological diseases, bone degeneration, periodontitis, tendonitis, spinal injury, head trauma, plastic surgery, alopecia, skin whitening and/or wrinkle eliminating, comprising: a) pre-treating the stem cells by culturing the stem cells in a culture medium comprising 0.1 μg/ml to 20 μg/ml of ligustilide to increase the expression of differentiation-promoting genes in the stem cells, increase the expression of homing-promoting genes in the stem cells, and/or decrease the expression of inflammatory genes in the stem cells, wherein the culture medium does not comprise insulin; and b) administering an effective amount of stem cells pre-treated in step a) to a subject suffering from digestive diseases, hepatic diseases, renal diseases, neurological diseases, bone degeneration, periodontitis, tendonitis, spinal injury, head trauma and/or alopecia or to a subject in need of plastic surgery, skin whitening and/or wrinkle eliminating.