Patent ID: 9707268
Date: 2017-07-18
CPC Classifications: A61K,A61P,C07K

Claim:
1. A method of treating a subject having a condition in which selective agonism of the angiotensin II type 2 (AT2) receptor is desired and/or required, comprising administering to the subject an effective amount of a cyclic peptide compound consisting of the amino acid sequence Xaa 1 -Asp-Arg-Val-Abu/Ala-Ile-His-Abu/Ala comprising a thioether-bridge linkage between the side chains of Abu/Ala at position 5 and Abu/Ala at position 8, wherein Xaa 1 is selected from the group consisting of Lys, Tyr, Asp, Ile, Asn and Ser; wherein said condition is diabetes, myocardial infarction, renal hypertension, stroke, alopecia, an inflammatory lung disorder, fibrosis, or wherein said condition requires augmentation of erythropoiesis.