Patent ID: 9701948
Date: 2017-07-11
CPC Classifications: C12N,C12P,C12Y

Claim:
1. A genetically modified Escherichia coli ( E. coli ) comprising a recombinant nucleotide sequence encoding 2-keto-acid decarboxylase; a deletion in an eutE gene: and a mutation in each of genes set forth in group (a) or group (b): (a) adhE, yqhD, adhP, eutG, yiaY, and yjgB genes, wherein said mutation reduces alcohol dehydrogenase activity of products of said genes; or (b) adhE, yqhD, adhP, eutG, fucO, and yjgB genes, and wherein said mutation reduces isobutyraldehyde reductase activity of products of said genes.