Patent ID: 9668959
Date: 2017-06-06
CPC Classifications: A61K,A61P,A61Q

Claim:
1. A method for decreasing melanin production, secretion, accumulation, or a combination thereof for treating or ameliorating a hyper-pigmentation skin condition or for cosmetic lightening of skin in a human subject, the method comprising contacting a skin cell with an effective amount of an A3 adenosine receptor antagonist, wherein the A3 adenosine receptor antagonist is selected from the group consisting of a dihydropyridine, a pyridine, a pyridinium salt, a triazoloquinazoline, an imidazoquinoline, an isoquinoline, a triazolopurine, a deazapurine, a pyrazolo-triazolo-pyrimidine, a triazolo-triazolo-pyrimidine, imidazolo-triazolo-pyrimidine, a xanthine, a flavonoid, and derivatives thereof, and wherein the skin condition is other than vitiligo.