Patent ID: 9713623
Date: 2017-07-25
CPC Classifications: A61K,C08G,C08L,C12N

Claim:
1. A compound of Formula I or Formula II: wherein: T and V are each independently selected from the group consisting of an amphiphilic moiety, a hydrophobic moiety, a hydrophilic moiety, and a therapeutic moiety and W is a cationic moiety selected from the group consisting of a small amine and a polyamine, wherein: (a) the amphiphilic moiety is selected from the group consisting of a jeffamine, a polysorbate, a poloxamer and a lipoloxamer; (b) the hydrophilic moiety is selected from the group consisting of an amine-terminated polyethylene glycol (NH (c) the hydrophobic moiety is selected from the group selected from the group consisting of an amine-terminated polypropylene glycol (NH (d) the therapeutic agent is selected from the group consisting of oligonucleotides and oligomers capable of complementary binding to DNA or RNA sequences; and X is a linker, wherein at least one of T, V or W is a polymer and at least one W is always present.