Patent ID: 9656020
Date: 2017-05-23
CPC Classifications: A61M,G16H

Claim:
1. A controller for controlling a glucagon pump, the controller comprising: an input arranged to receive an input signal indicative of a measured blood glucose concentration; an output arranged to provide a pulsed glucagon pump drive signal, each pulse being arranged to cause a glucagon pump to deliver a volume of glucagon; and a processing unit arranged to set a pulse frequency of the pump drive signal in dependence upon the input signal, such that when the input signal indicates that the measured blood glucose concentration is above a threshold concentration the pulse frequency is zero and when the input signal indicates that the measured blood glucose concentration is below the threshold concentration the pulse frequency is increased as the measured blood glucose concentration decreases, wherein the processing unit comprises a CMOS based circuit arranged to implement an integrate and fire model to simulate the electrical response of a pancreatic alpha cell to blood glucose concentration, the CMOS based circuit comprising metal-oxide-semiconductor field-effect transistors (MOSFETs), wherein the CMOS based circuit is conductively coupled to said input, said input being conductively coupled to an output of a glucose sensor and arranged to receive an output current from the glucose sensor, and further arranged to generate action potentials approximating action potentials of alpha cells and wherein said action potentials determine said pulsed glucagon pump drive signal.