Patent ID: 9644037
Date: 2017-05-09
CPC Classifications: C07K,C12N,C12Q,C12Y,G01N

Claim:
1. An isolated monoclonal antibody, or antigen binding fragment thereof, comprising a heavy chain variable region and a light chain variable region, wherein the heavy chain variable region comprises a heavy chain complementarity determining region (H-CDR)1, a H-CDR2, and a H-CDR3 of the heavy chain variable region set forth as SEQ ID NO: 6, and wherein the light chain variable region comprises a light chain complementarity determining region (L-CDR)1, a L-CDR2, and a L-CDR3 of the light chain variable region set forth as SEQ ID NO: 7, wherein the heavy chain complementarity determining regions and the light chain complementarity determining regions are determined using the methods of Kabat, Chothia or IMGT, and wherein the monoclonal antibody or antigen binding fragment specifically binds to an epitope comprising a phosphorylated threonine at amino acid position 1989 of SEQ ID NO: 1.