Patent ID: 9545397
Date: 2017-01-17
CPC Classifications: A61K,A61P,C07K,C12Q,G01N

Claim:
1. A method of treating a patient diagnosed with Pompe disease which comprises administering to the patient a therapeutically effective dose of 1-deoxynojirimycin, wherein the patient expresses a mutant a-glucosidase selected from the group consisting of the a-glucosidase mutations E262K, P266S, P285R, P285S, L291F, L291H, L291P, M318K, G377R, A445P, Y455C, Y455F, P457L, G483R, G483V, M519V, S529V, P545L, G549R, L552P, Y575S, E579K, A610V, H612Q, A644P, and AN470.