Patent ID: 9632085
Date: 2017-04-25
CPC Classifications: C12Q,G01N,Y02A

Claim:
1. A method for determining antibiotic susceptibility of a microbe, the method comprising: (i) obtaining a sample comprising a microbe, wherein the microbe is bound to a microbe-targeting substrate, wherein the microbe-targeting substrate comprises a solid substrate and a microbe-binding molecule on a surface of the solid substrate, wherein the microbe-binding molecule comprises at least one carbohydrate recognition domain and N-terminus of the microbe-binding molecule is linked to the solid substrate; (ii) incubating the solid substrate-bound microbe in the presence of at least one antibiotic agent for a pre-determined period of time; and (iii) detecting the growth, viability, or functional response of the microbe to the antibiotic agent, wherein reduced growth, viability, or function in the presence of the antibiotic agent relative to a reference or control sample indicates that the microbe is susceptible to the antibiotic agent.