Patent ID: 9676827
Date: 2017-06-13
CPC Classifications: A61K,A61P,C07K,C12N,C12Y,Y02A

Claim:
1. A fusion protein comprising: (a) an antigen-presenting cell (APC)-binding domain or a CD91 receptor-binding domain, located at the N-terminus of the fusion protein; (b) a protein transduction domain, located at the C-terminus of the APC-binding domain or the CD91 receptor-binding domain, wherein the protein transduction domain is a fusion polypeptide consisting of: (c) an antigen of a pathogen or a cancer cell, located at the C-terminus of the protein transduction domain; wherein: the pathogen is at least one selected from the group consisting of human papillomavirus (HPV), PRRSV, HIV-1, flu virus, Dengue virus, hepatitis C virus (HCV), hepatitis B virus (HBV), and porcine circovirus 2 (PCV2); and further wherein: the cancer cell is at least one selected from the group consisting of non-small cell lung cancer, breast carcinoma, melanoma, lymphomas, colon carcinoma, and hepatocellular carcinoma.