Patent ID: 9683015
Date: 2017-06-20
CPC Classifications: C07K

Claim:
1. The peptide C α -amide having the general formula (II): in which: Peptide1 represents the R k is an integer ranging from 1to 100, Xaa represents, independently of one another, an amino acid residue originating from an amino acid of formula H—Xaa-OH, and when k is greater than or equal to 2, each of said Xaa is connected to its neighboring Xaa via a peptide bond, R one of R D represents a hydrogen atom or a solid support suitable for solid phase peptide synthesis (SPPS), C is absent or represents an arm that can be used for SPPS, B represents: in which E is absent or represents the -(Xaa) i represents an integer ranging from 1 to 20, each Xaa represents, independently of one another, an amino acid residue, and when i is greater than or equal to 2, each of said Xaa is connected to its neighboring Xaa via a peptide bond, the others of said R A represents an aryl or heteroaryl radical chosen from the group comprising in which * indicates the point of attachment of A in the compound of formula (II), R R in which * indicates the point of attachment of A in the compound of formula (II), at least one of X the radical of formula: in which * indicates the point of attachment of A in the compound of formula (II), at least one of X Y one of said Y thereby promoting an intramolecular rearrangement of said peptide C