Patent ID: 9533993
Date: 2017-01-03
CPC Classifications: A61P,C07D

Claim:
1. A process for the preparation of a compound of Formula VI(a), VI(b) or VI(c): wherein R R R the process comprising: (a) reacting a compound of Formula VII(a), VII(b) or VII(c), respectively: wherein R with a compound of Formula VIII(a): wherein LG X is selected from C(O)R R under conditions to provide a compound of Formula IX(a), IX(b) or IX(c), respectively: wherein R R R (b) reacting the compound of Formula IX(a), IX(b) or IX(c) with a metal catalyst in the presence of an oxidant under conditions to provide the compound of Formula VI(a), VI(b) or VI(c), respectively, wherein in the compounds of Formulae VI(a)-(c), VII(a)-(c), VIII(a) and IX(a)-(c), one or more available hydrogens in R