Patent ID: 9572781
Date: 2017-02-21
CPC Classifications: A61K,A61P

Claim:
1. A pharmaceutical composition comprising a first population of non-opioid analgesic/opioid analgesic drug-containing microparticles, wherein the drug-containing microparticles comprise: (a) a first core comprising a non-opioid analgesic drug; (b) a first coating disposed over the first core, comprising an opioid analgesic drug; and (c) a second coating disposed over the first core, comprising a water-insoluble polymer; and further comprising a second population of non-opioid analgesic drug-containing particles, wherein the second population of non-opioid analgesic drug-containing particles comprise: (i) a second core comprising the non-opioid analgesic drug; and (ii) a third coating comprising a water-insoluble polymer disposed over the second core, wherein the water-insoluble polymer of the third coating is the same as or different from the water-insoluble polymer of the second coating.