Patent ID: 9539301
Date: 2017-01-10
CPC Classifications: A61K,A61L,C07K

Claim:
1. A topical composition for transdermal delivery of a gamma melanocyte stimulation hormone (MSH) analogue, said topical composition comprising: a. the gamma MSH analogue selected from the group consisting of: b. at least one non-toxic solvent; c. a solute modifier comprising at least one compound selected from the group consisting of 3,3′-thiodipropionic acid or an ester or salt thereof, an oxindole alkaloid, a polyphenolic flavonoid, a sugar adduct of a gluconuride, an isoflavone, phosphatidyl serine, phosphatidyl choline, Vitamin D d. at least one substance that induces in situ generation of cAMP or cGMP; and e. a skin stabilizer comprising at least one compound selected from the group consisting of an aliphatic carboxylic acid having from about 8 to 32 carbon atoms, an ester of said aliphatic carboxylic acid with an aliphatic alcohol having about 2 to 20 carbon atoms, wherein said ester has a total of about 9 to 36 carbon atoms, and Vitamin D