Patent ID: 9717736
Date: 2017-08-01
CPC Classifications: A61K,A61P,C07D

Claim:
1. A pharmaceutical composition for treating cancer ameliorated by inhibition of mTOR in a warm blooded animal having said cancer comprising a therapeutically-effective amount of a compound of formula 1ap: or a pharmaceutically acceptable salt thereof, in association with a pharmaceutically-acceptable diluent or carrier, in combination with a cytostatic agent selected from: tamoxifen, fulvestrant, toremifene, raloxifene, droloxifene, iodoxyfene, bicalutamide, flutamide, nilutamide cyproterone acetate, goserelin, leuprorelin, buserelin, metestrol acetate, anastrozole, letrozole, vorazole, exemestane, and finasteride.