Patent ID: 9567636
Date: 2017-02-14
CPC Classifications: A61P,C12Q

Claim:
1. A method for treating a condition selected from the group consisting of an infectious disease, a chronic inflammatory disease characterized by abnormal infiltration of neutrophils or eosinophils, rheumatic arthritis and acute ischemic stroke in a subject in need thereof, said method comprising: (a) obtaining a sample from the subject, said sample comprising nucleic acids, which comprise a polynucleotide encoding an HLA-B allele; (b) detecting the absence of a HLA-B*1301 allele in the polynucleotide encoding the HLA-B allele in the sample from the subject by analyzing the nucleic acids in the sample; and (c) administering dapsone to the subject, thereby treating the condition in the subject, wherein the subject has a reduced risk of developing dapsone hypersensitivity syndrome (DHS) in response to the administering of the dapsone as compared to a subject with at least one allele of HLA-B*1301.