Patent ID: 9623415
Date: 2017-04-18
CPC Classifications: B01L

Claim:
1. A molecular diagnostic test device, comprising: a housing; a sample preparation module including a sample input module and a filter assembly disposed within the housing, the sample input module including an inlet port and an outlet port, the inlet port configured to receive an input sample; a sample actuator operatively coupled to the sample input module, the sample actuator configured to apply a force to the sample input module to convey the input sample from the outlet port through the filter assembly when the sample actuator is moved from a first position to a second position, the sample actuator including a tab configured to irreversibly engage a portion of the housing when the sample actuator is moved to the second position to maintain the sample actuator in the second position; an amplification module configured to receive the input sample from the sample preparation module, the amplification module defining a reaction volume and including a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample; and a detection module defining a detection channel configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample, wherein the amplification module, the sample preparation module, and the detection module are integrated within the housing.