Patent ID: 9592203
Date: 2017-03-14
CPC Classifications: A61K,H05K

Claim:
1. A tablet oral formulation for enhancing release of budesonide in the colon, consisting essentially of: a tableted extended release core comprising 9 mg of budesonide, hydroxypropyl cellulose and optionally other excipients, wherein the tableted extended release core is macroscopically homogeneous; and a gastro-resistant coating on the tableted extended release core, the gastro-resistant coating comprising a copolymer of methacrylic acid and methyl methacrylate in a 1:1 ratio, a copolymer of methacrylic acid and methyl methacrylate in a 1:2 ratio, and optionally other excipients to control the release of said budesonide from the solid oral formulation, wherein following oral administration of a single dose to a human, the formulation provides a mean AUC