Patent ID: 9669007
Date: 2017-06-06
CPC Classifications: A61K,A61P,A61Q

Claim:
1. Process for producing an aqueous gel comprising hyaluronic acid, vitamin C, and a stabilizing agent selected from the metabisulfites, comprising the following steps: a. preparing a mixture comprising crosslinked or non-crosslinked hyaluronic acid and/or a salt thereof with a molar mass of between 1000 Da and 10 MDa, from 0.1 to 20.0% by weight of vitamin C in its acid form, or its equivalent in ascorbate derived from a vitamin C salt, from 0.01 to 1.00% by weight of a stabilizing agent selected from the metabisulfites, and an aqueous solution added so that the hyaluronic acid content is between 0.01 and 100 mg/ml, in order to form a hydrogel, and wherein the hydrogel optionally further comprises an additive or base; b. degassing the mixture before the hydrogel being formed is completely swollen.