Patent ID: 9657311
Date: 2017-05-23
CPC Classifications: A61P,C12N

Claim:
1. A lentiviral expression vector comprising: (i) 300-1100 nucleotides of an MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence, and (ii) a transgene sequence under control of an MHC class I or β2 microglobulin promoter, wherein the MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence is selected from the group consisting of a β2 microglobulin upstream promoter sequence, an HLA-A2 upstream promoter sequence, HLA-B7 upstream promoter sequence, an HLA-E upstream promoter sequence and an HLA-DRα upstream promoter sequence.