Patent ID: 9556243
Date: 2017-01-31
CPC Classifications: A61K,A61M,C07K,G01N

Claim:
1. A system for the production of a solution rich in interleukin-1 receptor antagonist (IL-1ra) from a multiple component material, comprising: a filter configured to filter a first component from the multiple component material and to allow a remaining multiple component material to pass; a separation system to receive the remaining multiple component material, including; wherein a second component comprising a buffy coat of the remaining multiple component material is operable to be separated from a third component of the remaining multiple component material within the separation container by the buoy system; a withdrawal container connected to the filter; non-centrifugal means for isolating cytokine-producing cells; and a solid extraction material for producing a liquid volume comprising a solution rich in IL-1ra; wherein the withdrawal container is configured to be connected to the withdrawal port and draw the second component from the separation container through the withdrawal port and through the filter into the withdrawal container; wherein the first component includes cytokine-producing cells; and wherein the second component is operable to separate the cytokine-producing cells from the filter to obtain a liquid volume comprising cytokine-producing cells.