Patent ID: 9599612
Date: 2017-03-21
CPC Classifications: G01N

Claim:
1. A method of analyzing an analyte, the method comprising: (A) exposing a target-receptor layer that comprises a plurality of target receptors adapted to bind a target substance selected from bacteria and spores in a fluid that comprises the analyte including the target substance; and (B) performing label-free interrogation of the target-receptor layer for a presence of the target substance bound thereto while subjecting the target-receptor layer to a laminar flow of the fluid flowing at a flow speed in a range of from 2.7 mm/s to 4.05 mm/s that is controlled based on calibration data for the selectivity of binding of the target substance relative to binding of at least one non-target substance that can interfere with detection of the target substance by binding to the target receptors thereby providing a higher specificity of detection of the target substance in the analyte compared to a corresponding specificity of detection with the fluid being stationary, and wherein the target substance is a spore of