Patent ID: 9675644
Date: 2017-06-13
CPC Classifications: A01N,A61K,A61L,C08L,C12N

Claim:
1. A biological composition suitable for implantation or grafting to a human patient comprising: a mixture of mechanically selected biologic material derived from bone marrow from cut vertebral bodies including cortical and cancellous bone of a human cadaver donor having non expanded whole cells and non-whole cellular components including each of vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, and extracellular components wherein the mixture is cleaned and packed for processing in a cold media of DMEM without L-glutamine or HEPES; and wherein the mixture further comprises a protectant or cryoprotectant of polyampholyte to form a coating on the mixture including the non-whole cellular components of the mixture prior to cryopreservation to create a poiyampholyte coated mixture, the coated mixture when prepared for implantation by thawing is compatible with biologic function.