Patent ID: 9617157
Date: 2017-04-11
CPC Classifications: A61K,A61P,B82Y,C01B,C01P,C07K,Y02A,Y10S

Claim:
1. A method for providing a stable pore in a lipid bilayer membrane comprising: positioning one or more elements at one or more of an intracellular end and an extracellular end of a tubular nanostructure, positioning the tubular nanostructure across a lipid bilayer membrane, wherein the tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions configured to form a pore in the lipid bilayer membrane and including at least one ligand configured to bind one or more cognates on the membrane, and reversibly blocking the pore with the one or more elements to control transport of molecules through the tubular nanostructure.