Patent ID: 9650379
Date: 2017-05-16
CPC Classifications: A61P,C07D

Claim:
1. A compound of the following formula I, an isomer thereof, or a pharmaceutically acceptable salt thereof: wherein X is C or N; Rh is hydrogen, halogen, —CF A is selected from the group consisting of Rm and Rn are each independently hydrogen, halogen, C B is selected from the group consisting of aryl, heteroaryl, C 3-12 cycloalkyl, and C 3-12 cycloalkenyl, wherein the aryl, heteroaryl, C 3-12 cycloalkyl and C 3-12 cycloalkenyl may each independently be unsubstituted or substituted with halogen, —C 1-5 alkyl, —NH 2 , —OH, —OC 1-5 alkyl or —CF 3 at one or more hydrogen atoms thereof, and the dotted line denotes a single or double bond; Q is aryl, heteroaryl, —C R R R k Ra and Rb are each independently hydrogen, halogen, —C m is 0, 1 or 2; Rc and Rd are each independently hydrogen, halogen, ═O, —C n is 0, 1 or 2; and Re is hydrogen, halogen, —CF