Patent ID: 9746468
Date: 2017-08-29
CPC Classifications: C12Q,G01N

Claim:
1. A sensor device for detecting a target molecule, comprising: a detecting electrode having a surface capable of attaching a thiol; a sensor chip substrate on which the detecting electrode is located; a reference electrode located on the sensor chip substrate that is electrically coupled to the detecting electrode; and a ternary self-assembled monolayer formed on the surface that includes a molecular capture probe having a thiol region, a linear alkanethiol molecule having one thiol region, and a linear alkanedithiol molecule having two thiol regions, wherein each of the molecular capture probe, the linear alkanethiol molecule, and the linear alkanedithiol molecule is immobilized on the surface, and wherein the molecular capture probe includes a region for receiving a target substance having a complimentary region that couples with the region of the molecular capture probe to generate a detectable electrical signal measured between the detecting electrode and the reference electrode during a coupling event.