Patent ID: 9724292
Date: 2017-08-08
CPC Classifications: A61K,A61Q

Claim:
1. A stable skin care composition for improving the appearance of aging skin, the stable skin care composition comprising: a. about 0.001% to about 5% of an artichoke leaf extract; b. about 0.001% to about 5% of a carob fruit extract, wherein the carob fruit extract comprises an oligogalactomannan; c. a dermatologically acceptable carrier; d. a pH of less than 7; e. wherein the composition excludes materials that complex with the artichoke leaf extract and the carob fruit extract; and f. wherein the artichoke leaf extract and the carob fruit extract are present at an amount to provide a synergistic increase in the up-regulation of at least one epidermal-associated gene selected from the group consisting of KRT2, KRT6A, CLDN1, LOR, FLG, IVL, KRT10, AQP3, and KRT14 according to an ex vivo tissue analysis.