Patent ID: 9700648
Date: 2017-07-11
CPC Classifications: A61L,A61P,C08L

Claim:
1. A composition comprising a substantially dry, free-flowing powdered mixture of about 10 to about 90 wt. % at least partially solvatable chitosan particles containing amino groups and about 90 to about 10 wt. % at least partially solvatable oxidized polysaccharide particles containing aldehyde groups, which mixture is sterilized and in sealed packaging and wherein the amino group functionality and molecular weight of the chitosan and the aldehyde group functionality and molecular weight of the oxidized polysaccharide are such that the particles when deposited onto a surgical site or wound moistened with bodily fluids will adhere to such site or wound and will adhere to one another by inter-particle crosslinking reaction of amino groups on the chitosan particles with aldehyde groups on the polysaccharide particles, and thereby form an uncohesive, solid sheet-like body having an inhomogeneous surface appearance and an inhomogeneous internal structure that breaks apart into smaller pieces if peeled away from the surgical site or wound, wherein substantially dry means the powder contains less than 10 wt. % water.