Patent ID: 9624152
Date: 2017-04-18
CPC Classifications: A61K,A61P,C07C,C07D,C07F

Claim:
1. A method of inhibiting sterol synthesis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a compound of formula I and a pharmaceutically acceptable vehicle, to thereby inhibit sterol synthesis in the patient, wherein formula I is represented by: or a pharmaceutically acceptable salt thereof, wherein: (a) each occurrence of m is independently an integer ranging from 0 to 5; (b) each occurrence of n is independently an integer ranging from 3 to 7; (c) X is (CH 2 ) z , wherein z is an integer from 0 to 4; (d) each occurrence of R 1 , R 2 , R 11 , and R 12 is independently H, (C 1 -C 6 )alkyl, or phenyl, wherein R 1 , R 2 , R 11 , and R 12 are not each simultaneously H; and (e) each occurrence of Y 1 and Y 2 is independently OH, COOH, COOR 3 , wherein: R