Patent ID: 9687464
Date: 2017-06-27
CPC Classifications: A61K,A61P

Claim:
1. A conjugate comprising: (a) at least one polymer selected from the group consisting of amine-terminated poly(ethylene glycol) and succinimide-terminated poly(ethylene glycol), and (b) at least one flavonoid selected from the group consisting of amine-terminated (−)-epigallocatechin gallate, carboxyl-terminated (−)-epigallocatechin gallate, and succinimide-terminated (−)-epigallocatechin gallate (EGCG); wherein the polymer is conjugated at the C6 and/or C8 of the A ring of the flavonoid; and wherein the flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation.