Patent ID: 9616031
Date: 2017-04-11
CPC Classifications: A61K,B01J,C09B

Claim:
1. A method for encapsulating particles of a water-insoluble material within a capsule of a water-insoluble polymer, comprising: (a) dispersing particles of the water-insoluble material or a solution containing the water-insoluble material in a first aqueous phase containing a first surfactant to obtain a first dispersion, wherein the water-insoluble material comprises or consists of at least one polymer; (b) collecting the particles of the water-insoluble material coated with the first surfactant; (c) washing the collected particles; (d) adding an aqueous suspension containing the washed surfactant-coated water-insoluble material particles to a polymer solution containing the water-insoluble polymer of the capsule to obtain a polymer mixture; and (e) dispersing the polymer mixture in a second aqueous phase containing a second surfactant to obtain a second dispersion comprising the particles of the water-insoluble material encapsulated within the capsule of the water-insoluble polymer, wherein the polymer of the water-insoluble material and the water-insoluble polymer are different, and wherein the water-insoluble polymer has a faster degradation rate than the polymer of the water-insoluble material.