Patent ID: 9668967
Date: 2017-06-06
CPC Classifications: A61K

Claim:
1. A depot formulation comprising: i) a lipid matrix; ii) at least one thiolated antioxidant; iii) optionally at least one bioactive agent; and iv) optionally at least one chelating agent; wherein said lipid matrix comprises: a) at least one diacyl glycerol and/or tocopherol; b) at least one phospholipid; c) at least one oxygenated organic solvent; and d) optionally at least one fragmentation agent; wherein the formulation may comprise up to 20 wt. % water provided that at least 3% wt. % of c) is also present; and wherein the formulation generates at least one non-lamellar phase upon exposure to an aqueous fluid.