Patent ID: 9730879
Date: 2017-08-15
CPC Classifications: A61K,A61Q,C07H

Claim:
1. A solventless process for the production of carbohydrate partial esters, comprising the steps of: (a) mixing, in the absence of solvent, C (b) adding, with continuous stirring, one or more glycoses containing 5 to 12 carbon atoms, and one or more emulsifiers comprising carbohydrate partial esters, to said catalytically-active system from step (a), wherein an esterification reaction dispersion is formed; wherein the improvement comprises increasing the esterification reaction rate by the steps of: (c) adding sodium hypophosphite prior to mixing in step (a) or prior to stirring in step (b); (d) removing water from the resulting mixture with continuous stirring at a temperature of up to 100° C., and under a pressure of up to 50 mbar; and (e) continuing the esterification reaction under a pressure of up to 50 mbar and at a temperature of up to 125° C., with continuous stirring, until the content of the C wherein the potassium carbonate is mixed in an amount of 0.06 mol to 0.16 mol per mol of glycoses; wherein the sodium hypophosphite is added in an amount of 0.01 mol to 0.1 mol per mol of glycoses; and wherein the so-produced carbohydrate partial esters have an average degree of esterification of 1 to 4.