Patent ID: 9738690
Date: 2017-08-22
CPC Classifications: A61K,A61P,C07K,C12N,C12Q

Claim:
1. A method of treating progressive multifocal leukoencephalopathy (PML) or progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome (PML-IRIS) in a subject, the method comprising: providing a VP1 protein of polyoma virus JC (JCV), administering the VP1 protein of JCV to the subject, and administering an TLR-7 agonist or an TLR-8 agonist, thereby treating progressive multifocal leukoencephalopathy (PML) or progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome (PML-IRIS) in the subject.