Patent ID: 9744138
Date: 2017-08-29
CPC Classifications: A61K,A61P,C12Y

Claim:
1. A method for the treatment of uterine fibroids in a patient comprising: injecting or inserting into the uterine fibroid a composition comprising: (a) a thermally responsive polymer having a lower critical solution temperature (LCST) that is less than or equal to the body temperature of said patient; and (b) collagenase, wherein said composition is formulated such that the thermally responsive polymer entraps and maintains the stability of the collagenase and is non-toxic and biodegradable, wherein the collagenase is from wherein said composition is injected at a temperature that is less than said lower critical solution temperature (LCST) to provide about 0.06 to about 1 mg collagenase per 1 cm