Patent ID: 9631016
Date: 2017-04-25
CPC Classifications: A61K,A61P,C07K

Claim:
1. A pen-injector device containing a liquid pharmaceutical formulation comprising an isolated IL-6 antibody having a light chain variable region and a heavy chain variable region, said light chain variable region comprising: a complementarity determining region light chain 1 (CDRL1) amino acid sequence of SEQ ID NO:132 comprising the sequence S-X a CDRL2 amino acid sequence of SEQ ID NO:133 comprising the sequence D-X a CDRL3 amino acid sequence of SEQ ID NO:134 comprising the sequence X said heavy chain variable region comprising: a complementarity determining region heavy chain 1 (CDRH1) amino acid sequence of SEQ ID NO:135 comprising the sequence G-F-X a CDRH2 amino acid sequence of SEQ ID NO:136 comprising the sequence K-X a CDRH3 amino acid sequence of SEQ ID NO:137 comprising the sequence Q-L-W-G-X24-Y-A-L-D-X