Patent ID: 9561212
Date: 2017-02-07
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound selected from: dimethyl ((R,S,R,1S,1′S)-((2S,2′S,5S,5′S)-5,5′-(5,5′-([1,1′-biphenyl]-4,4′-diyl)bis(1H-imidazole-5,2-diyl))bis(2-methylpyrrolidine-5,1-diyl))bis(1-((2R,4R,6S)-2-cyclopropyl-6-methyltetrahydro-2H-pyran-4-yl)-2-oxoethane-2,1-diyl))dicarbamate; dimethyl ((S,R,R,1S,1′S)-((2S,2′S,5S,5′S)-5,5′-(5,5′-([1,1′-biphenyl]-4,4′-diyl)bis(1H-imidazole-5,2-diyl))bis(2-methylpyrrolidine-5,1-diyl))bis(1-((2S,4R,6R)-2-cyclopropyl-6-methyltetrahydro-2H-pyran-4-yl)-2-oxoethane-2,1-diyl))dicarbamate; dimethyl ((S,R,S,1S,1′S)-((2S,2′S,5S,5′S)-5,5′-(5,5′-([1,1′-biphenyl]-4,4′-diyl)bis(1H-imidazole-5,2-diyl))bis(2-methylpyrrolidine-5,1-diyl))bis(1-((2R,4S,6S)-2-cyclopropyl-6-methyltetrahydro-2H-pyran-4-yl)-2-oxoethane-2,1-diyl))dicarbamate; dimethyl (4,4′-biphenyldiylbis(1H-imidazole-4,2-diyl((2S,5S)-5-methyl-2,1-pyrrolidinediyl)(1-(3-cyano-3-methylcyclobutylidene)-2-oxo-2,1-ethanediyl)))biscarbamate; and dimethyl (4,4′-biphenyldiylbis(1H-imidazole-4,2-diyl((2S,5S)-5-methyl-2,1-pyrrolidinediyl)(1-(3-cyano-3-methylcyclobutylidene)-2-oxo-2,1-ethanediyl)))biscarbamate; or a pharmaceutically acceptable salt thereof.