Patent ID: 9649342
Date: 2017-05-16
CPC Classifications: A61K,A61L,A61P

Claim:
1. A process for creating a composition for disc regeneration, said process comprising: (a) morselizing donor disc material, wherein the donor disc material comprises healthy cells obtained from a non-degenerative level of a spine of a person in need of disc regeneration; (b) extruding the donor disc material to form an extruded material that comprises chondrocytes and an extracellular matrix; (c) sequestering platelets from whole blood or bone marrow in order to obtain platelet rich plasma; (d) extracting and concentrating the platelets from the platelet rich plasma into a platelet lysate through a cell membrane lysis procedure that uses at least one of thrombin and calcium chloride; and (e) mixing the chondrocytes, the extracellular matrix, a bone marrow aspirate from the person, and the platelet lysate, wherein the bone marrow aspirate comprises stem cells, to form a composition for disc regeneration wherein the composition for disc regeneration is a mixture, wherein the mixture comprises growth factors and within the mixture there is socialization between the chondrocytes and the stem cells due to cell-to-cell signaling, thereby initiating differentiation of the stem cells into chondrocytes.