Patent ID: 9675708
Date: 2017-06-13
CPC Classifications: A61K,A61P,B60R,B82Y,G01N

Claim:
1. A functionalized biocompatible nanoparticle for penetrating through a mammalian cell membrane and delivering intracellularly a bioactive molecule for modulating a cellular function, said functionalized biocompatible nanoparticle comprising: a central nanoparticle having one or more functional groups attached thereto, a cell penetrating peptide for penetrating through a membrane of said mammalian cell, wherein said cell penetrating peptide is attached via a first linker molecule to a first functional group on said central nanoparticle, and a bioactive molecule for modulating a function of said mammalian cell, wherein said bioactive molecule is attached via a second linker molecule to a second functional group on said central nanoparticle; wherein said cell penetrating peptide and said bioactive molecule are independently attached to said central nanoparticle via attachment of said cell penetrating peptide to said first linker molecule and attachment of said bioactive molecule to said second linker molecule.