Patent ID: 9598496
Date: 2017-03-21
CPC Classifications: A61P,C07K

Claim:
1. An antibody which specifically reacts with human transferrin receptor (TfR), wherein said antibody inhibits cell growth on TfR-expressing tumor cells, and wherein said antibody comprises a heavy chain variable region having CDR consisting of the heavy chain first complementarity determining region (VH CDR1) of SEQ ID NO: 31, the heavy chain second complementarity determining region (VH CDR2) of SEQ ID NO: 32, and the heavy chain third complementarity determining region (VH CDR3) of SEQ ID NO: 33, and a light chain variable region having CDR consisting of the light chain first complementarity determining region (VL CDR1) of SEQ ID NO: 34, the light chain second complementarity determining region (VL CDR2) of SEQ ID NO: 35, and the light chain third complementarity determining region (VL CDR3) of SEQ ID NO: 36.