Patent ID: 9676847
Date: 2017-06-13
CPC Classifications: A61K,C07K,C12N,C12P,G01N

Claim:
1. An isolated interleukin-17 (IL-17) antibody which binds, as a major epitope, an epitope consisting of a sequence of the human interleukin-17A (IL-17A) as set forth in SEQ ID NO: 8, the antibody comprising: a Kabat heavy chain complementarity determining region-1 (VH-CDR1) amino acid sequence which is identical to the VH-CDR1 of the VH region comprising the amino acid sequence as set forth in SEQ ID NO: 3 or SEQ ID NO: 5; a Kabat heavy chain complementarity determining region-2 (VH-CDR2) amino acid sequence which is identical to the VH-CDR2 of the VH region comprising the amino acid sequence as set forth in SEQ ID NO: 3 or SEQ ID NO: 5; a Kabat heavy chain complementarity determining region-3 (VH-CDR3) amino acid sequence which is identical to the VH-CDR3 of the VH region comprising the amino acid sequence as set forth in SEQ ID NO: 3 or SEQ ID NO: 5; a Kabat light chain complementarity determining region-1 (VL-CDR1) amino acid sequence which is identical to the VL-CDR1 of the VL region comprising the amino acid sequence as set forth in SEQ ID NO: 4; a Kabat light chain complementarity determining region-2 (VL-CDR2) amino acid sequence which is identical to the VL-CDR2 of the VL region comprising the amino acid sequence as set forth in SEQ ID NO: 4; and a Kabat light chain complementarity determining region-3 (VL-CDR3) amino acid sequence which is identical to the VL-CDR3 of the VL region comprising the amino acid sequence as set forth in SEQ ID NO: 4.