Patent ID: 9545437
Date: 2017-01-17
CPC Classifications: A61K,A61P,C07K

Claim:
1. A method of treating a cancer associated with the over-expression of the gene of SEQ ID NO: 3 (DEPDC1 V1) or 5 (DEPDC1 V2) in a subject, said method comprising administering to said subject a vaccine comprising one or more isolated peptide(s) of less than 15 amino acids, said peptide is selected from the group consisting of: (a) a peptide comprising the amino acid sequence of SEQ ID NO: 12, and (b) a peptide having cytotoxic T cell inducibility and comprising the amino acid sequence of SEQ ID NO: 12, in which 1 or 2 amino acids are substituted; wherein, (i) the second amino acid from the N-terminus of the amino acid sequence of SEQ ID NO: 12 is substituted with phenylalanine, methionine, or tryptophan, and/or (ii) the C-terminal amino acid of the amino acid sequence of SEQ ID NO: 12 is substituted with phenylalanine, leucine, tryptophan, or methionine.