Patent ID: 9539244
Date: 2017-01-10
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method for treatment of a disease mediated by FXR, wherein the disease is selected from the group consisting of chronic intrahepatic cholestatic disease; chronic extrahepatic cholestatic disease; liver fibrosis; obstructive inflammatory disorders of the liver; chronic inflammatory disorders of the liver; liver cirrhosis; liver steatosis; hepatitis: liver failure; liver ischemia; chemotherapy associated steatohepatitis (CASH); acute liver failure; inflammatory bowel disease; lipid and lipoprotein disorders; Type II Diabetes; Type I Diabetes, Non-Alcoholic Fatty Liver Disease (NAFLD); Non-Alcoholic Steatohepatitis (NASH); obesity; metabolic syndrome; dyslipidemia; acute myocardial infarction; acute stroke; thrombosis; atherosclerosis; a non-malignant hyperproliferative disorder; a malignant hyperproliferative disorder; hepatocellular carcinoma; colon adenoma; polyposis; colon adenocarcinoma; breast cancer; pancreatic adenocarcinoma; Barrett's esophagus; Primary Biliary Cirrhosis (PBC); and Primary Sclerosing Cholangitis (PSC), the method comprising administering to a patient in need thereof a compound according to the Formula (1).