Patent ID: 9587279
Date: 2017-03-07
CPC Classifications: C12Q

Claim:
1. A method comprising: measuring levels of RNA expression of genes consisting of DPP4, SERPINA1, MATN2, and PROS1 in a test tissue or cell sample from a subject by microarray analysis and/or quantitative polymerase chain reaction using primers or probes, wherein at least one of the primers or probes is SEQ ID NO: 18, 33, 42, or 50; and treating the subject for thyroid cancer when thyroid cancer cells in the test tissue or cell sample have at least a 50% increase in the measured levels of RNA expression of genes consisting of DPP4, SERPINA1, and PROS1 and at least a 50% decrease in the measured level of MATN2 RNA expression compared to RNA expression levels of genes consisting of DPP4, SERPINA1, MATN2, and PROS1 in a benign thyroid standard sample.