Patent ID: 9657045
Date: 2017-05-23
CPC Classifications: C07H,C12N,C12P,C12Y,C13K

Claim:
1. A process for producing a particulate composition comprising crystalline α,α-trehalose dihydrate with an α,α-trehalose content of 98.0% by weight or more, on a dry solid basis, said process comprising the steps of: allowing to act on liquefied starch an α-glycosyltrehalose-forming enzyme derived from a microorganism of the genus allowing a glucoamylase to act on the resulting mixture to obtain a saccharide solution comprising α,α-trehalose; precipitating crystalline α,α-trehalose dihydrate from said saccharide solution by a controlled cooling method or semi-controlled cooling method; collecting the precipitated crystalline α,α-trehalose dihydrate by a centrifuge; and ageing and drying the collected crystals to obtain a particulate composition comprising crystalline α,α-trehalose dihydrate; wherein a natural or recombinant cyclomaltodextrin glucanotransferase derived from a microorganism of the genus wherein said controlled cooling method is a cooling method where the liquid temperature “T” at the time “t” is basically expressed by the formula: wherein “τ” is the operation time established for a crystallization step, “T wherein said semi-controlled cooling method is a cooling method, where the liquid temperature “T” is allowed to linearly or stepwisely decrease against the time “t” in order to keep the variation (T wherein said particulate composition has a degree of crystallinity for crystalline α,α-trehalose dihydrate of 90.0% or higher, when calculated based on its powder X-ray diffraction profile.