Patent ID: 9714261
Date: 2017-07-25
CPC Classifications: A61P,B01J,C07B,C07C,C07D,C07F,C07K

Claim:
1. A compound of formula (I) wherein: X n represents an integer ranging from 3 to 10; R R R R L represents a single bound or a linker selected from aryl, heteroaryl, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, cycloalkynyl or a combination thereof; said groups being optionally substituted by at least one group selected from oxo, thioxo, hydroxyl, ether, carboxylic acid, ester, alkyl, cycloalkyl, alkenyl, cycloalkenyl, heterocyclyl, alkynyl, cycloalkynyl, amine, amide, guanidine, imino, nitro, nitrile, azide, sulfhydryl, sulfide, thioester, thioether, sulfite, sulfate, phosphine, phosphite and phosphate, halogen; said groups being optionally interrupted or terminated by —O—, —S—, —NR optionally L additionally comprises a residue of a reactive group through which L is bounded to M; M represents: a reactive function selected from carboxylic acid, nitrile, ester, activated ester, aldehyde, acetal, ketone, ketal, alkyne, azide, alkene, diene, maleimide, protected maleimide, hydroxyl, phenol, 2-aminophenol, thiol, thioester, thioether, thiosulfonate, primary amine, secondary amine, tertiary amine, alkoxyamine, aniline, amide, phosphine, alkyl phosphate, isocyanates, isothiocyanates, hydrazide, hydrazine, tosylate ester, vinyl sulfone, carbamate, carbonate ester, 4-phenyl-1,2,4-triazole-3,5-dione, sulphide, azidoalkyl and azidoaryl; or a bioactive group selected from amino acid, biogenic amine, peptide, heteropeptide, protein, antibody or fragment thereof, monobody, affibody, antibody construct, saccharide, polysaccharide, benzylguanine, biotin, avidin, nucleotide, oligonucleotide, microRNA, hapten, aptamer, ligand, enzyme, enzyme substrate, steroid, hormone, porphyrin, neurotransmitters, sympatomimetic drug, vitamin, phosphonate, nanocarrier, liposome, dendrimer, carbon nanotube and combinations thereof; said aryl or heteroaryl being optionally further substituted by one or more substituents selected from hydroxyl; linear, cyclic or branched alkyl comprising 1, 2, 3, 4, 5 or 6 carbon atoms; aryl; heteroaryl; heterocyclyl; arylheterocyclyl; alkoxy; halogen; nitro; cyano; azido; aldehyde; boronato; phenyl; CF wherein the aryl vector is selected from the group consisting of: