Patent ID: 9623015
Date: 2017-04-18
CPC Classifications: A61K,A61P

Claim:
1. A method of preventing hematologic cancer relapse in a patient comprising: (A) administering to the patient an effective amount of an anti-cancer agent until a stable cumulative incidence of response in the patient is achieved, wherein the anti-cancer agent is a tyrosine kinase inhibitor (TKI) that inhibits phosphorylation of BCR-ABL selected from the group consisting of imatinib, dasatinib, nilotinib, bosutinib, and ponatinib; and (B) administering to the patient an effective amount of a peroxisome proliferator-activated receptor (PPARγ) agonist, wherein the PPARγ agonist is a thiazolidinedione that inhibits transcription of Signal Transducer and Activator of Transcription 5 (STAT5).