Patent ID: 9566325
Date: 2017-02-14
CPC Classifications: A61K,A61P,C07K,C12N

Claim:
1. A method for treating a herpes simplex virus type 2 (HSV-2) infection in a mammal, wherein the method comprises the steps of: (a) administering to the mammal a priming preparation comprising a vector encoding an HSV-2 antigen under the control of a promoter, wherein the vector encodes a full-length gD sequence comprising a sequence of SEQ ID NO: 1; (b) after step (a), administering to the mammal a first boosting preparation comprising the HSV-2 antigen encapsulated in liposomes; and (c) after step (b), administering to the mammal a second boosting preparation comprising the vector encoding the HSV-2 antigen and the liposomal-encapsulated HSV-2 antigen, wherein the vector is administered intramuscularly and the liposomal-encapsulated antigen is administered intranasally.