Patent ID: 9578227
Date: 2017-02-21
CPC Classifications: G02B,H04N

Claim:
1. An autofocus imaging system for a microscope system, the autofocus imaging system comprising: an image sensor arrangement configured to acquire a primary image data of an object of interest and first and second autofocus image data of an oblique section of the object of interest, wherein the image sensor arrangement comprises a tilted autofocus image sensor configured to acquire the first autofocus image data and, at a later time, the second autofocus image data; and a calculation unit configured to generate a polar error signal of a focus position of the microscope system based on a comparison of a first data relating to the first autofocus image data with a second data relating to the second autofocus image data, wherein the comparison comprises: wherein, for the comparing the first contrast function with the second contrast function, the calculation unit is further configured to correct the second contrast function for translation of the object of interest and then for subtracting the first and second contrast functions, or filtered or transformed versions of the first and second contrast unctions, from each other, resulting in an S-curve.