Patent ID: 9541561
Date: 2017-01-10
CPC Classifications: G01N

Claim:
1. A method for measuring a concentration of beta-amyloid in a sample, comprising: preparing magnetic particles on which primary capture antibodies specifically bound to beta-amyloid are adsorbed; decomposing a biomaterial including the beta-amyloid; binding the beta-amyloid to the primary capture antibodies; binding secondary capture antibodies labeled with a fluorescent material to the magnetic particles bound to the beta-amyloid to form a complex; disposing the complex over a channel pattern of a photo field effect transistor having a photocurrent that is changed according to an amount of incident light; and measuring the photocurrent changed by light excited from the complex to quantify the concentration of the beta-amyloid existing in the biomaterial, wherein the photo field effect transistor includes: a light filter layer disposed on the upper surface of the channel pattern and sidewalls of the first and second wiring electrodes, wherein the channel pattern is defined by a side of the insulating layer and a side of the light filter layer, the first and second wiring electrodes defining sidewalls of the channel pattern, wherein disposing the complex comprises fixing the complex onto a surface of the light filter layer and over the channel pattern of the photo field effect transistor by a source of an external magnetic field located under the semiconductor substrate, and wherein the light filter layer passes through only a wavelength of light excited from the fluorescent material.