Patent ID: 9745321
Date: 2017-08-29
CPC Classifications: A61P,C07D

Claim:
1. A fused pyrimidine compound represented by formula I, a pharmaceutically acceptable salt, a hydrate, a solvate, an optical isomer or a prodrug thereof, wherein: X is S or O; Q is C or N; R R (R Cy is heterocyclyl selected from: A is N or CR D is N or CR E is N or CR G is N or CR Z is N or CR Z′ is N or CR A, D, E, Z and G are not N at the same time; each of R R R each of R  and a substituted or unsubstituted C each of R (CR wherein said alkyl, alkenyl, alkynyl, cycloalkyl, carbocycle, heterocycle, heterocycloalkyl, aryl, or heterocyclyl may optionally be substituted by the substituent selected from the group consisting of: a deuterium, a halogen, —CN, —CF Y is O, S, or NR m and k are independently 0, 1, 2, 3, 4, 5 or 6.