Patent ID: 9670517
Date: 2017-06-06
CPC Classifications: B01J,C12N,C12P,C12Q

Claim:
1. A method of synthesizing a gene block of a desired sequence greater than 100 bases, the method comprising: a) providing a plurality of solid supports, wherein at least one solid support contains between 1-8% by weight controlled pore glass; b) synthesizing oligonucleotides on the solid supports, wherein the oligonucleotides comprise a set of oligonucleotides that are partially complementary to at least one other oligonucleotide in the set, and the set of oligonucleotides as a group contain the desired sequence of the gene block; c) detaching the oligonucleotides from the solid supports; d) combining the oligonucleotides under conditions to synthesize the gene block.