Patent ID: 9678085
Date: 2017-06-13
CPC Classifications: A61P,C07K,G01N

Claim:
1. A method of detecting a prion protein in a sample, comprising: contacting the sample with (i) a ligand having a length of 6-mers or less and having an amino acid sequence selected from the group consisting of SEQ ID NOS: 114, 108, 51-59, 61, 101-107, 109, 111-113, 115, 117-120, 140-153, 195-211, 213-214, 218, and 219 or (ii) a ligand consisting of the amino acid sequence of SEQ ID NO: 212, wherein the ligand is capable of binding to one or more prion proteins, a fragment thereof, or a peptide derived therefrom under conditions sufficient to cause formation of a complex between the prion protein, the fragment thereof, or the peptide derived therefrom and the ligand; and detecting the complex in the sample.