Patent ID: 9687847
Date: 2017-06-27
CPC Classifications: B01L,G01N

Claim:
1. A microfluidic platform for optical biosensing, the platform comprising: an optical substrate; a layer provided on the substrate; and a channel formed within the layer and defined by the layer and the substrate through which fluid can flow, the channel including a constriction that narrows along a length of the channel to a point at which it is physically sized and configured to trap a microsphere suspended in the fluid when the fluid flows through the channel, wherein the constriction comprises two opposed inwardly-extending members that narrow a top portion of the channel, wherein the inwardly-extending members are defined by lower surfaces and upper surfaces that form opposing edges that contact opposite sides of the microsphere, and wherein the lower surfaces are horizontal, the upper surfaces are vertical, and the edges are 90-degree edges.