Patent ID: 9678074
Date: 2017-06-13
CPC Classifications: C07K,C12Q,G01N

Claim:
1. An isolated protein comprising the amino acid sequence of SEQ ID NO: 2 and at least one sequence feature selected from the group consisting of: a. a cysteine residue at the position corresponding to position 27 of SEQ ID NO:2; b. a leucine residue at the position corresponding to position 29 of SEQ ID NO:2 c. a serine residue at the position corresponding to position 30 of SEQ ID NO:2 d. a tyrosine residue at the position corresponding to position 32 of SEQ ID NO:2 e. a serine residue at the position corresponding to position 34 of SEQ ID NO:2 f. a proline residue at the position corresponding to position 37 of SEQ ID NO:2; g. a leucine residue at the position corresponding to position 40 of SEQ ID NO:2; h. an alanine residue at the position corresponding to position 42 of SEQ ID NO:2; i. a lysine residue at the position corresponding to position 44 of SEQ ID NO:2; j. an aspartic acid residue at the position corresponding to position 48 of SEQ ID NO:2; k. a tyrosine residue at the position corresponding to position 50 of SEQ ID NO:2; l. a leucine residue at the position corresponding to position 111 of SEQ ID NO:2; m. a leucine residue at the position corresponding to position 112 of SEQ ID NO:2; n. an aspartic acid residue at the position corresponding to position 118 of SEQ ID NO:2; o. an alanine residue at the position corresponding to position 120 of SEQ ID NO:2; p. a cysteine residue at the position corresponding to position 122 of SEQ ID NO:2; q. a cysteine residue at the position corresponding to position 152 of SEQ ID NO:2; r. a valine residue at the position corresponding to position 157 of SEQ ID NO:2; s. an asparagine residue at the position corresponding to position 160 of SEQ ID NO:2; t. a leucine residue at the position corresponding to position 161 of SEQ ID NO:2; u. an arginine residue at the position corresponding to position 163 of SEQ ID NO:2 v. a leucine residue at the position corresponding to position 165 of SEQ ID NO:2; w. a threonine residue at the position corresponding to position 166 of SEQ ID NO:2; x. an alanine residue at the position corresponding to position 173 of SEQ ID NO:2; and y. a cysteine residue at the position corresponding to position 178 of SEQ ID NO:2 wherein the isolated protein has at least one activity selected from the group consisting of eliciting an antibody that selectively binds a protein consisting of SEQ ID NO:2, selectively binding a compound that binds to a protein consisting of SEQ ID NO:2, activating expression of the JAK/STAT pathway, and inducing expression of at least one ISG listed in