Patent ID: 9675747
Date: 2017-06-13
CPC Classifications: A23L,A23V,A61M,C12G,C12N

Claim:
1. A method of causing cancer cells in blood of a patient to act as cavitation nuclei, comprising the steps of: sequentially depositing a plurality of test blood samples from the patient with first cancer cells in a single chamber; exposing each of said test blood samples, when in the single chamber, to sound energy at a different respective one of a plurality of sweeping frequencies generated by a sound energy source, wherein the entire volume of each of said test blood samples is exposed; determining an inactivation efficiency of the first cancer cells for each of said test blood samples; determining a resonant sweeping frequency that (a) within the range spanned by the plurality of sweeping frequencies, optimally destroys the first cancer cells and (b) has center frequency in the range 350 kHz to 15 MHz and sweep frequency bandwidth between 0.1 percent and 7 percent of the center frequency; circulating the blood of the patient out of the patient via a first catheter, through a vessel coupled with a second sound energy source, and back into the patient through a second catheter; and exposing the blood to sound energy generated by the second sound energy source at said resonant sweeping frequency to cause second cancer cells in the blood and of same type as the first cancer cells to act as cavitation nuclei and implode while untargeted cells in the blood remain viable, wherein the entire volume of the blood contained by said vessel is exposed to said resonant sweeping frequency.