Patent ID: 9585871
Date: 2017-03-07
CPC Classifications: A61K,A61P

Claim:
1. A method for curing a canine animal of a Leishmania infantum parasite infection, wherein said canine animal is in need of a cure from the Leishmania infantum parasite infection, said method comprising the step of administering fexinidazole to the canine animal in an effective amount, whereby: the fexinidazole is metabolized in the canine animal to produce a parasiticidally effective amount of fexinidazole sulfone and sulfoxide metabolites, which are responsible for killing the the metabolites are present in the canine animal's plasma in concentrations exceeding 2 ng/mL for at least one hour of each day throughout the fexinidazole administration; and wherein the fexinidazole administration is over a course whereby the cured canine animal does not relapse for at least 180 days post fexinidazole administration; thereby curing the canine animal.