Patent ID: 9695127
Date: 2017-07-04
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound of Formula 2, or an ester or pharmaceutically acceptable salt thereof, for treating HIV wherein R 1 is selected from hydrogen, aliphatic, aryl, heteroaliphatic, oxo, heteroaryl, or combinations thereof; R 2 is selected from hydroxyl, alkoxy, thiol, thioether, amine, or combinations thereof; R 3 is selected from —(CH 2 ) n R 6 wherein n is zero to ten and R 6 is selected from aliphatic, heteroaliphatic, aryl, heteroaryl, or combinations thereof, —N═NR 6 R 7 wherein each R 6 and R 7 independently are selected from hydrogen, aliphatic, heteroaliphatic, aryl, heteroaryl, or combinations thereof, and —C═CR 6 R 7 wherein each R 6 and R 7 independently are selected from hydrogen, aliphatic, heteroaliphatic, aryl, heteroaryl, or combinations thereof; R 4 is selected from alkyl having from 5 to 10 carbon atoms, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, cycloalkynyl, heteroaliphatic, aryl, heteroaryl, and combinations thereof; X is selected from nitrogen, oxygen, or carbon, CH 2 , or CHR 1 ; Y is selected from nitrogen or CH; and provided that the compound is not (E)-4-((3-chlorophenyl)diazenyl)-5-hydroxy-3-(4-nitrophenyl)-1H-pyrazole-1-carbothioamide.