Patent ID: 9713642
Date: 2017-07-25
CPC Classifications: A61K,A61P

Claim:
1. A method of treating a disease or condition in a subject, comprising administering to the subject an oral pharmaceutical composition comprising itraconazole and one or more pharmaceutically acceptable polymers, wherein the composition exhibits an AUC (a) an AUC 0-t which is 80% to 125% of about 10 h*ng/ml to about 18.5 h*ng/ml per milligram of itraconazole following administration of the composition to the subject under fed conditions, (b) an AUC 0-t which is 80% to 125% of about 6.9 h*ng/ml to about 13.8 h*ng/ml per milligram of itraconazole following administration of the composition to the subject under fasting conditions, (c) an AUC 0-t which is 80% to 125% of about 8.8 h*ng/ml to about 14.8 h*ng/ml per milligram of itraconazole following administration of the composition to the subject under fed conditions, and (d) an AUC 0-t which is 80% to 125% of about 7.0 h*ng/ml to about 12.4 h*ng/ml per milligram of itraconazole following administration of the composition to the subject under fasting conditions.