Patent ID: 9566355
Date: 2017-02-14
CPC Classifications: A61K,C07F,C12Q

Claim:
1. A method for imaging bacteria in a subject comprising: a) administering a contrast agent to a subject, wherein said contrast agent is selected from the group consisting of: wherein M is a metal ion, and wherein R is a linker moiety selected from the group consisting of: i) an amino acid, ii) a peptide, iii) a divalent branched or unbranched carbon chain comprising from about 2 to about 30 carbon atoms, iv) a divalent branched or unbranched carbon chain comprising from about 2 to about 30 carbon atoms, which the chain is substituted with one or more hydroxyl groups or oxo groups, v) a divalent branched or unbranched carbon chain comprising from about 2 to about 30 carbon atoms, wherein one or more of the carbon atoms in the chain is replaced with an aryl ring, a hetoroaryl ring, or with a non-peroxide —O—, —S— or —NH—, vi) —C(═O)NH(CH vii) —C(═O)NH(CH viii —CH ix) a divalent heteroaryl group, and b) performing imaging of said subject and detecting a signal from said contrast agent if said subject is infected with bacteria.