Patent ID: 9732142
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07K,C08F,C08L

Claim:
1. A composition comprising nanovesicles and encapsulated within the aqueous core of the nanovesicles, an antibody, wherein the nanovesicles comprise an amphiphilic block copolymer having a hydrophilic block formed from 2-methacryloyloxy ethyl phosphorylcholine and a hydrophobic block formed from 2-(diisopropyl)amino ethyl methacrylate, the ratio of the degree of polymerization of the hydrophilic to hydrophobic block is in the range of 1:2.5 to 1:8, the nanovesicles have a diameter in the range of 50 to less than 1,000 nm, and the degree of polymerization of the hydrophilic block is about 20-25 and the degree of polymerization of the hydrophobic block is about 70-75.