Patent ID: 9629927
Date: 2017-04-25
CPC Classifications: A61K,B82Y,C01B

Claim:
1. A soluble SWNT construct having the structure SWNT-(DNA 1,2 (cDNA 1 -peptide) m -(cDNA 2 -M*tetraazacyclododecane-1,4,7,10-tetra acetic acid (DOTA)) n ) x , such that cDNA 1 is linked to the peptide, cDNA 2 is linked to DOTA and DNA 1,2 is linked to the SWNT; and, wherein cDNA 1 and cDNA 2 independently are non-identical oligomers and DNA 1,2 is an oligomer with a sequence complementary to cDNA 1 and cDNA 2 ; and, wherein said DNA 1,2 is the sequence shown in SEQ ID NO: 1, said cDNA 1 is the sequence shown in SEQ ID NO: 2 and said cDNA 2 is the sequence shown in SEQ ID NO: 3; and, wherein said peptide is an antibody or a targeting cyclic RGD or an NGR peptide ligand, M* is a radionuclide or a contrast agent, x is 1 to 300; and m and n are independently 1 to 300.