Patent ID: 9566277
Date: 2017-02-14
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method for inhibiting poly (ADP-ribose) polymerase (PARP) in a subject in need thereof, comprising administering to the subject a pharmaceutical composition comprising one or more pharmaceutically acceptable carriers or excipients, and a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein A and B are taken together with the attached carbon atoms to form an aryl or heteroaryl, wherein the aryl or heteroaryl is each independently and optionally substituted with one or more groups selected from the group consisting of an alkyl, halogen, hydroxyl, alkoxyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, —C(O)OR R D, E, and G are each independently selected from the group consisting of a nitrogen atom and C(R R R alternatively, R R m is selected from the group consisting of 0, 1 and 2; and n is selected from the group consisting of 0, 1 and 2.