Patent ID: 9540671
Date: 2017-01-10
CPC Classifications: A61K,A61P,C07K,C12N,C12P,C12Y,Y02A

Claim:
1. A hetero-oligomeric enzyme comprising: a catalytic domain of a RNA triphosphatase; a catalytic domain of a guanylyltransferase; a catalytic domain of a N7-guanine methyltransferase; and a catalytic domain of a DNA-dependent RNA polymerase, wherein the catalytic domain of a DNA-dependent RNA polymerase is linked covalently or non-covalently with the catalytic domain of a RNA triphosphatase, the catalytic domain of a guanylyltransferase, or the catalytic domain of a N7-guanine methyltransferase, and wherein the hetero-oligomeric enzyme is non-natural.