Patent ID: 9730893
Date: 2017-08-15
CPC Classifications: A61K,C12N

Claim:
1. A liposome comprising at least one lipid bilayer, wherein said at least one lipid bilayer comprises at least one type of cationic lipid, and optionally at least one type of neutral lipid, wherein an outermost layer of the at least one lipid bilayer of the liposome comprises at least one type of anionic lysolipid, wherein said at least one type of anionic lysolipid is negatively charged at a pH within a range of 4 to 8, and wherein the at least one type of anionic lysolipid is present in a sufficient concentration to provide the liposome with an anionic surface charge at a pH within a range of 4 to 8, or to provide the liposome with a net zero surface charge at a pH within a range of 4 to 8.