Patent ID: 9682067
Date: 2017-06-20
CPC Classifications: A61K,A61P

Claim:
1. A method of improving cognitive function of a human subject afflicted with a neurodegenerative disease in need thereof, comprising the step of administering to said subject a composition comprising an effective amount of an activator specific for the GluR6 kainate receptor wherein the activator specifically induces GluR6 receptor and not other glutamate receptors and significantly decreases the averaged after-hyperpolarization (AHP) amplitude in neurons of said subject, thereby improving the cognitive function of said subject, wherein improving cognitive function comprises enhancing a learning ability selected from the group consisting of conditioning learning, spatial learning and location learning, and wherein said activator is (2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid.