Patent ID: 9745360
Date: 2017-08-29
CPC Classifications: A61K,A61P,C07K,Y02A

Claim:
1. A peptidic compound having the formula (I): or a salt or solvate thereof, wherein Z is a peptide moiety having the formula (II): wherein: X3 is an amino acid residue selected from Gln, Glu, and His, X12 is Ile, X14 is an amino acid residue having a side chain with a functionalized —NH X15 is an amino acid residue selected from Asp and Glu, X16 is an amino acid residue selected from Ser, Lys, Glu, and Gln, X17 is an amino acid residue selected from Arg, Lys, Glu, Gln, Leu, Aib, Tyr, and Ala, X18 is an amino acid residue selected from Ala, Arg, Aib, Leu, and Tyr, X19 is an amino acid residue selected from Ala, Val, and Aib, X20 is an amino acid residue selected from Pip, (S)MeLys, (R)MeLys, and (S)MeOrn, X21 is an amino acid residue selected from Asp, Glu, and Leu, X28 is an amino acid residue selected from Asn, Ala, Aib, and Ser, X29 is an amino acid residue selected from Gly, Thr, Aib, D-Ala, and Ala, X40 is either absent or is Lys, R R