Patent ID: 9539262
Date: 2017-01-10
CPC Classifications: A61K,A61P

Claim:
1. A method of reducing intraocular pressure comprising a step of administering an ophthalmic composition comprising 0.005% w/v latanoprost or a pharmaceutically acceptable salt thereof, 0.15% to 0.3% w/v castor oil, 0.2 to 0.75% w/v of polyethylene glycol hydroxystearate, and a pharmaceutically acceptable vehicle, wherein the ratio of oil to polyethylene glycol hydroxystearate is less than 1.0, wherein the composition is in the form of a self-emulsifying micro-emulsion with average droplet size of about 100 nm or less and a zeta potential is between −0.1 mV to −20 mV, wherein the composition does not comprise a cationic surfactant, and wherein the composition does not comprise a quaternary ammonium compound.