Patent ID: 9532947
Date: 2017-01-03
CPC Classifications: A61K,A61P

Claim:
1. A formulation for oral transmucosal administration of one or more active principles for treating a spastic crisis, wherein said one or more active principles are selected from the group consisting of tiemonium, phloroglucinol, and nefopam, with said one or more active principles being the only active principles in said formulation, wherein said one or more active principles are present in base form and/or in salt form, wherein when said tiemonium is present in said formulation, it is present in an amount between 2-25 mg; wherein when said phloroglucinol is present in said formulation, it is present in an amount between 2-40 mg; and wherein when said nefopam is present in said formulation, it is present in an amount between 2-20 mg, provided that the total amount of active principle in said formulation is between 2-50 mg, and wherein in said formulation, said one or more active principles are present in a state of stable and complete dissolution in an aqueous ethanol solution, said aqueous ethanol solution titrating to at least 35° ethanol and comprising 40% to 85% ethanol and 15% to 60% water.