Patent ID: 9744318
Date: 2017-08-29
CPC Classifications: A61K,A61M

Claim:
1. A powder aerosolization apparatus comprising: a housing comprising an outlet adapted to be inserted into a user's mouth and one or more bypass air openings, a receptacle support within the housing capable of supporting a receptacle containing a powder pharmaceutical formulation, a conduit in communication with the outlet and adapted to transport aerosolized powder from the receptacle to the outlet, and a puncturing mechanism within the housing to create in the receptacle one or more inlet openings and one or more powder outflow openings, wherein the powder outflow openings have a total area of from 0.2 mm wherein the outlet is in fluid communication with the one or more powder outflow openings and with the one or more bypass air openings so that upon a user's inhalation through the outlet, air flows through the one or more bypass air openings and through the receptacle to aerosolize the powder pharmaceutical formulation in the receptacle, wherein a ratio of airflow through the one or more powder outflow openings to the airflow through the one or more bypass openings at peak inhalation is from 1:10 to 1:40.