Patent ID: 9708390
Date: 2017-07-18
CPC Classifications: A61K,A61P,C07K

Claim:
1. A method of treating a neovascular disorder, the method comprising: administering to a subject having said neovascular disorder an effective amount of a PDGFRβ antagonist, wherein said PDGFRβ antagonist is an anti-PDGFRβ antibody that binds to the extracellular domain of PDGFRβ and neutralizes PDGFRβ activity, said antibody comprising a V LCDR1 has the amino acid sequence shown in SEQ ID NO:433; LCDR2 has the amino acid sequence shown in SEQ ID NO:434; LCDR3 has the amino acid sequence shown in SEQ ID NO:435; HCDR1 has the amino acid sequence shown in SEQ ID NO:436; HCDR2 has the amino acid sequence shown in SEQ ID NO:437; HCDR3 has an amino acid sequence selected from the group consisting of SEQ ID NOs:438-442.