Patent ID: 9566323
Date: 2017-02-14
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method for preventing human cervical cancer, comprising administering to a human a pharmaceutical composition comprising (a) (i) an L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, an L1 VLP of HPV type 18, or a combination thereof; and (ii) CIA05 as a deacylated non-toxic lipooligosaccharide (LOS), which is detoxificated by deacylation of lipid A of lipopolysaccharide isolated from E. coli ( Escherichia coli ); (b) a pharmaceutically acceptable carrier; and (c) aluminum hydroxide, with the proviso that the composition does not include bacterial DNA as an adjuvant.