Patent ID: 9709553
Date: 2017-07-18
CPC Classifications: A61K,A61P,C07K,C12N,G01N

Claim:
1. A method of isolating a population of human oligodendrocyte-biased glial progenitor cells, comprising the steps of: (a) providing a population of human neural cells or neural precursor cells and (b) recovering a population of A2B5+ and PSA-NCAM− human oligodendrocyte-biased glial progenitor cells from the provided population of human neural cells or neural precursor cells using only an agent that selectively binds to the CD140a ectodomain epitope of human PDGFαR, wherein the recovered population of cells has a higher percentage of said human oligodendrocyte-biased glial progenitor cells than when said recovering is carried out using antibodies directed against A2B5 and PSA-NCAM.