Patent ID: 9737533
Date: 2017-08-22
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method of treating an anxiety disorder selected from the group consisting of obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD), said method comprising administering to a patient in need thereof a therapeutically effective amount of a compound of Formula (I): or a stereochemically isomeric form thereof wherein n is selected from the group consisting of 0, 1 and 2; m is selected from the group consisting of 0, 1, and 2; R is selected from methyl or trifluoromethyl; R R is an N-containing heterocycle selected from the group consisting of (L-a), (L-b), (L-c), (L-d), (L-e), (L-f), (L-g) and (L-h) below wherein R R or CR wherein each W each R each R each q1, q2, q3 or q4 is independently selected from 0, 1 and 2; r is 0 or 1; s is 0 or 1; each R R each R each R wherein, in (L-e), t is 1, 2, or 3; when t is 1 or 2, R when t is 1 or 3, then CR wherein each R each R each u1 and u2 is independently 0, 1 or 2; v1 is selected from the group of 0, 1 and 2; v2 is selected from the group of 1 and 2; each z1 and z2 is independently selected from the group of 0, 1 and 2; each k1 and k2 is independently selected from the group of 0, 1 and 2; wherein, in (L-f) w is 1 or 2; wherein in (L-g), x is 0 or 1 and y is 1 or 2, provided when x is 0, y is 1 or 2, and when x is 1, y is 1; Z is CR Z is CR Z is NR wherein R wherein in (L-h), Q is O or N—R wherein each Het each Het each Het each halo is selected from the group consisting of fluoro, chloro, bromo and iodo; or a pharmaceutically acceptable salt or a solvate thereof.