Patent ID: 9676692
Date: 2017-06-13
CPC Classifications: C07C,C07D

Claim:
1. A method for producing a 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound represented by Formula (3): wherein R each of A each of A X represents a hydrogen atom or a halogen atom, and each X is optionally the same as or different from each other; R R Y represents a hydrogen atom, cyano, or C two adjacent Ys optionally form A each of A Y R R or represents that R R R R D-3 to D-5, D-7, D-9 to D-15, D-18 to D-36, and D-42 to D-49 represent aromatic heterocyclic rings represented by the following structural formulae: Z represents a halogen atom, cyano, nitro, C E-1, E-2, E-5, and E-7 represent saturated heterocycles represented by the following structural formulae: R R R R R R R R R R R R R R p1 represents an integer of 1 to 2; p2 represents an integer of 0 to 1; p3 represents an integer of 0 to 1; p4 represents an integer of 0 to 1; p5 represents an integer of 0 or 1; q2 represents an integer of 0 to 2; q3 represents an integer of 0 to 2; q4 represents an integer of 0 to 2; r represents an integer of 0 to 2; t represents an integer of 0 or 1, the method consisting of reacting an aromatic ketone compound represented by Formula (4) wherein R wherein R the base is selected from the group consisting of sodium acetate, potassium acetate, methylamine, ethylamine, n-propylamine, i-propylamine, n-butylamine, i-butylamine, t-butylamine, n-pentylamine, i-pentylamine, benzylamine, aniline, dimethylamine, diethylamine, di-n-propylamine, di-i-propylamine, di-n-butylamine, di-i-butylamine, di-n-pentylamine, di-i-pentylamine, pyrrolidine, piperidine, piperazine, morpholine, dibenzylamine, trimethylamine, triethylamine, tri-n-propylamine, tri-n-butylamine, tripentylamine, tribenzylamine, diisopropylethylamine, N-methylmorpholine, and combinations thereof, and the additive is selected from the group consisting of a C