Patent ID: 9732145
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07K

Claim:
1. An isolated monoclonal antibody or any antigen-binding fragment thereof which binds to Bacillus anthracis protective antigen, wherein the antibody comprises a heavy chain variable region comprising: a) the complementarity determining region CDRH1 comprising the amino acid sequence of IFTNYNMH denoted by SEQ ID NO. 3; b) the complementarity determining region CDRH2 comprising the amino acid sequence AIYPRTGDTSYNQKFKG denoted by SEQ ID NO. 4; and c) the complementarity determining region CDRH3 comprising the amino acid sequence ARDGFAY denoted by SEQ ID NO. 5; and a light chain variable region comprising: d) the complementarity determining region CDRL1 comprising the amino acid sequence RASQDISNYLN denoted by SEQ ID NO. 8; e) the complementarity determining region CDRL2 comprising the amino acid sequence YTSRLHS denoted by SEQ ID NO. 9; and f) the complementarity determining region CDRL3 comprising the amino acid sequence QQGKTLPWT denoted by SEQ ID NO. 10.