Patent ID: 9717733
Date: 2017-08-01
CPC Classifications: A61K

Claim:
1. A composition, comprising: a microvesicle derived from an edible plant; and a therapeutic agent conjugated to the microvesicle, the therapeutic agent chemically-linked to a plasma membrane of the microvesicle with a cross-linking agent, wherein the therapeutic agent is a phytochemical agent selected from curcumin, resveratrol, baicalein, equol, fisetin, and quercetin, and wherein the cross-linking agent is selected from the group consisting of N-ethylcarbodiimide (EDC), dicyclohexyl carbodiimide (DCC), homobifunctional disuccinimidyl, disuccinimidyl tartrate, 3-3′-dithiobis-propionimidate (DTBP), and ethylene glycol bis-succinimidyl succinate (EGS).