Patent ID: 9629907
Date: 2017-04-25
CPC Classifications: A61K,A61P,C07K,C12N,Y02A

Claim:
1. A composition consisting of: an isolated nucleic acid molecule that comprises a nucleic acid sequence that encodes an immunogen operably linked to regulatory elements that are functional in a human, wherein said immunogen is a pathogen antigen from a pathogen that enters a human host across mucosal tissue that is selected from the group consisting of: oral mucosa, other alimentary canal mucosa, olfactory mucosa, conjunctival mucosa, other respiratory tract mucosa, mucosa of mammary glands, and genitourinary tract mucosa; and an isolated nucleic acid molecule that comprises a nucleic acid sequence that encodes TECK, wherein said nucleic acid sequence that encodes TECK is operably linked to regulatory elements that are functional in a human, wherein said nucleic acid molecules are plasmids, further wherein said plasmids are constructed by inserting said coding sequences into the multiple cloning region of a pVax1 backbone, wherein said coding sequences are under the regulatory control of the cytomegalovirus promoter and bovine growth hormone polyadenylation signal.