Patent ID: 9746413
Date: 2017-08-29
CPC Classifications: B01L,C12M,G01N,G06K

Claim:
1. A system for capturing cells in single-cell format, comprising: an array defined on a broad face of a substrate, comprising: a plurality of pores, each pore in the plurality of pores displaced from at least one other pore in the plurality of pores and comprising: a chamber having an upstream end, and a pore channel, fluidly coupled to the chamber at a downstream end of the chamber, defined by a pore channel width configured to block egress of a cell, wherein each chamber of the plurality of pores is separated from an adjacent chamber by a barrier that is configured to blocks fluid flow in a direction parallel to fluid flow through the pore channel; an inlet channel directly fluidly coupled to the upstream end of each chamber of the plurality of pores; and an outlet channel directly fluidly coupled to each pore channel of the plurality of pores, wherein flow from the inlet channel is configured to reach the outlet channel only by way of the plurality of pores.