Patent ID: 9593069
Date: 2017-03-14
CPC Classifications: A61K,A61P,C07C

Claim:
1. A method comprising administering to a subject suffering from or susceptible to amyotrophic lateral sclerosis (ALS) an effective amount of a compound of a formula: or a pharmaceutically acceptable salt thereof, wherein: each R is independently hydrogen, halogen, optionally substituted C R L is a valence bond or a bivalent saturated or partially unsaturated, branched or unbranched C Ring A is a 3-8 membered saturated, partially unsaturated, or aryl monocyclic ring optionally containing 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; m is 0-5; each R at least one R a is independently wherein Q is a valence bond or a bivalent optionally substituted saturated or partially unsaturated, branched or unbranched C 1-10 hydrocarbon chain, wherein 1-3 methylene units of Q are optionally and independently replaced by —NR—, —N(R)C(O)—, —C(O)N(R)—, —N(R)SO 2 —, —SO 2 N(R)—, —O—, —C(O)—, —OC(O)—, —C(O)O—, —S—, —S(O)— or —SO 2 —; Ring B is a 3-8 membered saturated, partially unsaturated, or aryl monocyclic ring optionally containing 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; n is 0-5; each R R