Patent ID: 9561280
Date: 2017-02-07
CPC Classifications: A61K,A61P

Claim:
1. A method for enhancing the preservative efficacy of an aqueous solution, the method comprising adding bromfenac or a salt thereof to the aqueous solution, wherein the amount of bromfenac or a salt thereof added to the aqueous solution is 0.05% to 0.15%, wherein the aqueous solution is an aqueous base which contains (a) 0.001 to 0.002% of benzalkonium chloride and (b) 0.025% or higher and lower than 0.25% of a non-ionic surfactant, and wherein the aqueous solution has preservative efficacy with said bromfenac or salt thereof but does not have sufficient preservative efficacy without said bromfenac or salt thereof.