Patent ID: 9637538
Date: 2017-05-02
CPC Classifications: C07K,G01N

Claim:
1. A monoclonal chimeric comprising formed of: (i) two polypeptide chains, called heavy chains (H), of molecular weight from 40 kDa to 60 kDa, and (ii) two polypeptide chains, called light chains (L), of molecular weight from 20 kDa to 30 kDa, wherein each heavy chain (H) comprises: a heavy chain variable region (VH) of a monoclonal antibody chosen from the group consisting of monoclonal antibodies specific to monomorphic epitopes of HLA class II antigens, and a heavy chain constant region (CH) of a human immunoglobulin chosen from the group consisting of IgAs, IgGs and IgMs, and wherein at least one light chain (L) consists of the sequence SEQ ID NO: 5, and at least one heavy chain (H) is selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8.