Patent ID: 9546994
Date: 2017-01-17
CPC Classifications: G01N

Claim:
1. A method of identifying a predisposition for developing type 2 diabetes mellitus in a subject, said method comprising the step of measuring in a sample obtained from said subject the amount of at least four metabolites comprising: (a) a first group comprising the metabolites glycine, lysoPhosphatidylcholine acyl C18:2, and phosphatidylcholine acyl-alkyl C34:2; and (b) a second group comprising the metabolite acetylcarnitine C2; and optionally, preparing a hard or soft copy comprising values of amounts of metabolites determined; and wherein a decrease in the amount of glycine, lysoPhosphatidylcholine acyl C18:2, and phosphatidylcholine acyl-alkyl C34:2, and an increase in the amount of acetylcarnitine C2 as compared to the amount of the corresponding metabolites of a control is indicative of a predisposition to develop type 2 diabetes mellitus.