Patent ID: 9568468
Date: 2017-02-14
CPC Classifications: G01N

Claim:
1. A method for identifying an agent that modulates motor or sensory neuron axon regeneration in an extended third instar (ETI) Drosophila larva, comprising: (i)contacting with a test agent an ETI (ii) assessing motor or sensory neuron axon regeneration in the disrupted motor or sensory neuron axons by assessing one or more of growth of the disrupted motor or sensory neuron axons, neuromuscular junction formation, glial activation, motor or sensory neuron survival, or neuromuscular junction loss in the contacted ETI Drosophila larva, and (iii) identifying the test agent as an agent that modulates motor or sensory neuron axon regeneration if a result of the assessment of step (ii) in the presence of test agent differs from the result of the assessment in the absence of the test agent.