Patent ID: 9603808
Date: 2017-03-28
CPC Classifications: A61K

Claim:
1. A method of treating a condition in a subject with a disorder or condition responsive to the administration of an amphetamine, comprising orally administering an effective amount of an amphetamine or a pharmaceutical salt thereof in a formulation comprising a core comprising an amphetamine or a pharmaceutical salt thereof and at least one pharmaceutically acceptable excipient; a sustained release layer enclosing the core and a delayed release layer enclosing the sustained release layer, wherein when the formulation provides an 8 hour lag time during which the formulation releases no more than 10% of the total amphetamine or a pharmaceutical salt thereof followed by a sustained release period of 10-12 hours when the composition is placed in 700 ml aqueous solution of 0.1N HCl pH 1.1, for up to 2 hours followed by hours 2-6 in sodium phosphate buffer at pH 6.0; followed by hours 6-20 in sodium phosphate buffer, pH 7.2 at 37° C.±0.0.5° C., measured by the USP Apparatus I.