Patent ID: 9568486
Date: 2017-02-14
CPC Classifications: C07K,G01N

Claim:
1. A diagnostic reagent or kit for use in diagnosing an ectopic pregnancy in a mammalian subject consisting of: i. a ligand that binds Isthmin2 (ISM2), ii. a ligand that binds the pro-domain or extracellular (EC) domain of ADAM12, iii. a ligand that binds pregnancy specific beta-1 glycoprotein isoform 7 (PSG7), iv. a ligand that binds pregnancy specific beta-1 glycoprotein isoform 11 (PSG11), v. a ligand that binds pregnancy specific beta-1 glycoprotein isoform 9 (PSG9), and vi. a ligand that binds pregnancy specific beta-1 glycoprotein isoform 2 (PSG2); wherein at least one of the ligands is covalently or non-covalently joined with a detectable label or immobilized upon a substrate.