Patent ID: 9649388
Date: 2017-05-16
CPC Classifications: A61K,A61P,C12N

Claim:
1. A SAMiRNA(s)-magnetic nanoparticle(s) complex comprising: magnetic nanoparticle(s) comprising first hydrophobic material coated on a surface of a magnetic material; and a structure comprising second hydrophobic material, double stranded oligo RNA and hydrophilic material wherein the structure is represented by the following Formula (1): wherein: one of A and B is said hydrophilic material, the other one is said second hydrophobic material; X and Y are each independently a simple covalent bond or a linker-mediated covalent bond; and R is said double-stranded oligo RNA, and wherein the magnetic nanoparticle is positioned in a core by hydrophobic interaction between the first hydrophobic material and the second hydrophobic material, the structure is positioned in a shell, and the hydrophilic material of the structure is bound to the outermost side of the double-stranded oligo RNA.