Patent ID: 9646133
Date: 2017-05-09
CPC Classifications: A61B,C12M,G01N,G05B,G16B

Claim:
1. A computer-controlled micro-instrumentation biochemical reaction environment system, the system comprising: at least one microreaction device comprising a microreaction chamber for supporting at least one chemical reaction associated with a biological signaling pathway; an electrically-controllable microfluidic routing system for the controlled transport of picoliter to nanoliter quantities of fluids and gases, wherein the microfluidic routing system comprises at least a first electrical interface for receiving electrical signals, wherein the microfluidic routing system can transport at least one of a fluid or gas to and/or from the at least one microreaction chamber; one or more micro-instrumentation devices associated with a second electrical interface, wherein the one or more micro-instrumentation devices measure a plurality of physical quantities associated with a plurality of aspects of the biological signaling pathway; and at least one electronic processor configured to: produce processed measurement data based on information in the at least one electrical measurement signal; execute at least one numerical simulation modeling aspect associated with the biological signaling pathway; determine a control signal to cause at least one chemical reaction associated with a biological signaling pathway based on the numerical simulation modeling; and transmit, to the first interface, the control signal to control the routing of fluids and gases provided by the microfluidic routing system.