Patent ID: 9625463
Date: 2017-04-18
CPC Classifications: A61M,B01D,B01L,B03C,B04B,C12M,C12N,G01N

Claim:
1. An apparatus configured for fractionating a blood or bone marrow sample in a sterile tubing set installed on the apparatus, wherein the tubing set comprises: a) a first connecting member configured to receive the sample and deliver the sample to a rotatable container, b) said rotatable container installed in a centrifuge in the apparatus, wherein the rotatable container contains at least one processing chamber and is configured to rotate about an axis and thereby to apply centrifugal force to a blood or bone marrow sample in the chamber so as to separate cells from the sample according to a first cell characteristic; c) a second connecting member configured to receive a selected subset of cells that has been separated from the sample by the rotatable container and to deliver the subset to a cell separation column; d) said separation column installed in a column holder in the apparatus, which is configured such that cells can be delivered to the cell separation column by the second connecting member; and e) a third connecting member configured to recover cells that have been selected by the cell separation column in the holder according to a second cell characteristic and to deliver the selected cells to a product collection container; wherein the apparatus is configured to operate so that a sample is processed from the first connecting member of the tubing set through the rotatable container in the centrifuge and through the cell separation column in the column holder and a product thereof is delivered into the product collection container while maintaining sterility of the product throughout all the aforelisted components of the tubing set.