Patent ID: 9540395
Date: 2017-01-10
CPC Classifications: A61P,C07D

Claim:
1. A compound of the formula (I): wherein Ar/Het is selected from the group consisting of pyrazolyl, thiazolyl, oxazolyl, imidazolyl, thienyl, furanyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, and 1,2,4-triazolyl; Y is bond, CR a is 1-3; b is 0-3; m is 0-2; each occurrence of R each of R each occurrence of R each of R4 and R5 is, independently, selected from H, C1-C6 alkyl and F; R1 is: (i) hydrogen; or (ii) C6-C10 aryl, which is optionally substituted with from 1-3 R (iii) monocyclic or bicyclic heteroaryl having from 5-10 ring atoms, which is optionally substituted with from 1-3 R (iv) heterocyclyl having from 4-10 ring atoms, which is optionally substituted with from 1-3 R each occurrence of R R2 is selected from H, F, Cl, CF R3 is H, F, or Cl; or a pharmaceutically acceptable salt thereof.