Patent ID: 9664559
Date: 2017-05-30
CPC Classifications: G01J,G01N,G02B

Claim:
1. An image capture device comprising: a narrow-band optical irradiation system including a light source configured to emit light having a peak wavelength of a transmission spectrum; an imaging element including an array of pixels divided into a plurality of blocks including at least a first block adjacent to a second block, wherein the imaging element is sensitive to light of a predetermined range of wavelengths, and wherein an edge of the first block borders an edge of the second block; a metal thin-film filter provided in an optical path between the narrow-band optical irradiation system and the imaging element, wherein the metal thin-film filter includes a periodic microstructural pattern of an array of openings having a period shorter than a wavelength of light detected by the imaging element, wherein the metal thin-film filter includes a first region in the array of openings corresponding to the first block and a second adjacent region in the array of openings corresponding to the adjacent second block, the first region and the second adjacent region having the same microstructural pattern, and wherein a surface of the metal thin-film filter in each of the first region and the adjacent second region includes immobilized antigens or antibodies; and a signal processor configured to generate a signal based on a difference between an intensity of incident light at one or more pixels of the first block and an intensity of incident light at one or more pixels of the adjacent second block when a peak wavelength of a transmission spectrum of the incident light at the one or more pixels of the first block is different from the peak wavelength of the transmission spectrum of the light emitted from the light source and a peak wavelength of a transmission spectrum of incident light at the one or more pixels of the adjacent second block is the same as the peak wavelength of the transmission spectrum of the light emitted from the light source.