Patent ID: 9617289
Date: 2017-04-11
CPC Classifications: A61P,C07D,C07F

Claim:
1. The compound according to formula (RI) wherein Het is selected from the group consisting of: formula (a′), (b′), (c′), and (d′): wherein each X independently is C or N; wherein at least one X is N; each of R each R m is an integer from 0 to 6; each R each R R R each Z independently is C or N, provided that at least two Z are C; Q and V each independently represent C═O, SO p and s independently represent an integer from 0 to 3, wherein the sum of p and s minimally should be 2, and when p=0 or s=0 then the carbon atom marked with * is directly bound to W; R R W is selected from the group consisting of: SO, SO R R R aryl represents phenyl or naphthalenyl; heteroaryl represents a monocyclic 5 to 6 membered aromatic heterocycle containing one or more heteroatoms each independently selected from the group consisting of: O, S and N; or a bicyclic 8 to 12 membered aromatic heterocycle containing one or more heteroatoms each independently selected from the group consisting of: O, S and N; or a pharmaceutically acceptable addition salt or a solvate thereof.