Patent ID: 9719117
Date: 2017-08-01
CPC Classifications: C12N,C12P,Y02P

Claim:
1. A whole cell catalyst which comprises a transaminase and one selected from the group consisting of 1) an α-dioxygenase and 2) a combination of 2a) a recombinant fatty acid reductase and 2b) a phosphopantetheinyl transferase, wherein: the phosphopantetheinyl transferase phospho-pantetheinylates the fatty acid reductase, thereby forming a phosphopantetheinylated fatty acid reductase, the fatty acid reductase catalyzes the conversion of an ω-carboxy acid to a corresponding ω-oxo fatty acid, at least one of the phosphopantetheinyl transferase and transaminase is recombinant, when the catalyst comprises the transaminase and the α-dioxygenase, the transaminase is overexpressed, and when the catalyst comprises the transaminase and the combination of 2a) a recombinant fatty acid reductase and 2b) a phosphopantetheinyl transferase, the transaminase and/or the phosphopantetheinyl transferase is overexpressed.