Patent ID: 9575332
Date: 2017-02-21
CPC Classifications: B29D,B65B,G02B,G02C

Claim:
1. A method for applying an ophthalmic product having a lubricous and wettable surface, comprising the steps of: (1) obtaining a silicone hydrogel contact lens, (2) placing the silicone hydrogel contact lens in a lens package containing an in-package-coating solution, wherein the in-package-coating solution comprises: (A) a polyanionic polymer having carboxyl groups, (B) at least one water-soluble and thermally-crosslinkable polymeric material comprising azetidinium groups, (C) at least one decomposable-at-autoclave material, wherein the in-package-coating solution has a pH of from about 1.0 to about 4.0, provided that the molar charge ratio of the polyanionic polymer and the water-soluble and thermal-crosslinkable polymeric material comprising azetidinium groups is from 1:100 to 100:1 and no precipitation is formed after mixings, wherein the polyanionic polymer attaching and forming at least one layer coating on the surface of the silicone hydrogel contact lens, (3) sealing the lens package with the contact lens and the in-package-coating solution having the pH of from about 1.0 to about 4.0, (4) autoclaving said package with the contact lens and the in-package-coating solution therein, thereby inducing crosslinking reaction between azetidinium groups of the water-soluble polymeric material and the carboxyl groups of the polyanionic polymer to form a crosslinked hydrophilic coating on the surface of the silicone hydrogel contact lens immersed in the in-package-coating solution, wherein the decomposable-at-autoclave material is hydrolyzed to increase the pH to 6.5 to 7.5, wherein the silicone hydrogel contact lens with the crosslinked hydrophilic coating thereon has a surface wettability characterized by having an averaged water contact angle of about 80 degrees or less and having improved lubricity as compared to uncoated lenses.