Patent ID: 9594045
Date: 2017-03-14
CPC Classifications: G01N

Claim:
1. A method of electrochemically measuring an analyte in a fluid sample in the presence of an antioxidant, the method comprising the steps of: applying an electrical test sequence to an electrochemical biosensor, the biosensor comprising: an electrode system, a reagent including a redox mediator in electrical communication with the electrode system, and a receptacle configured to contact the fluid sample provided to the biosensor, with the fluid sample in fluidic contact with the reagent, wherein the test sequence comprises at least two direct current (DC) blocks, wherein a first DC block includes a slow-ramp bi-polar (SRBP) waveform having at least one SRBP recovery potential, wherein a second DC block includes a sequence alternating between at least one excitation potential and at least one recovery potential, and wherein a closed circuit condition of the electrode system is maintained during the at least two DC blocks; measuring current response information to the first DC block, including information from the at least one SRBP recovery potential; measuring current response information to the second DC block, including the at least one excitation potential and the at least one recovery potential; evaluating quantitatively a level of the antioxidant present in the fluid sample based at least in part upon current response information to the SRBP waveform; and determining an analyte concentration of the fluid sample based at least in part upon current response information from the excitation current response and the recovery current response, the determining compensating for the antioxidant.