Patent ID: 9637715
Date: 2017-05-02
CPC Classifications: C12M

Claim:
1. A microfluidic system comprising: a multi well plate, comprising a first well used as a flow inlet, a second well used as a cell/gel inlet, a third well used as an invasion chamber and a fourth well used as a flow outlet; a cell/gel loading channel in communication with the second well, passing under the third well and terminating at the fourth well; a flow channel in communication with the first well, passing under the third well and terminating at the fourth well; a microfluidic device comprising a plurality of microstructures, the plurality of microstructures comprising: wherein said invasion chamber comprises a rectangular region disposed between said invasion barrier and said perfusion barrier, such that said perfusion barrier and said invasion barrier form two opposite parallel sides of said rectangular region, and further wherein the microfluidic device is small enough to fit within a diameter of the third well in the multiple well plate, said diameter being about 7 millimeters or less.