Patent ID: 9724537
Date: 2017-08-08
CPC Classifications: A61B,A61K,A61N

Claim:
1. A method of treating atrial fibrillation using a photodynamic therapy by means of catheter ablation apparatus for the treatment of atrial fibrillation using photodynamic therapy, comprising a catheter for leading a photoradiation unit to an abnormal electrical conduction site between the left atrium and the pulmonary vein in a test subject, a light ray generator with which the abnormal electrical conduction site is irradiated, and a light ray transmitter to the abnormal electrical conduction site, the method comprises: administering a photosensitizer in the test subject at a dose per weight of 0.5 to 5 mg/kg such that a photosensitizer concentration in a plasma of the test subject becomes 10 to 30 g/ml at a site that causes atrial fibrillation; inserting catheter having photoradiation unit, the catheter transporting the photoradiation unit into the abnormal electrical conduction site between the left atrium and the pulmonary vein that causes atrial fibrillation in the test subject; and irradiating a light ray at the abnormal electrical conduction site 30 to 60 minutes after administration of the photosensitizer to separate the left atrium and the pulmonary vein in lines continuously with keeping the increase of temperature from before photoradiation of site to after irradiation within 10° C., wherein the photosensitizer is a water-soluble chlorine-based photosensitizer a semiconductor light or a LED light is used as the light ray, an intensity of the light ray is 2 to 30 W/cm