Patent ID: 9662337
Date: 2017-05-30
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method of treating or alleviating a disease or disorder selected from the group consisting of Alzheimer's disease, age-related cognitive decline and autism, the method comprising administering to a patient in need thereof a compound of the formula (I) or a pharmaceutically acceptable salt, solvate, or hydrate thereof, wherein R1 is selected from: A is selected from the group consisting of —CO—, —NH—, —O—, —S—, —SO—, and —SO ring structure B optionally contains one nitrogen atom; R2 is selected from the group consisting of H, a (1-4C) alkyl group optionally substituted with at least one fluoro atom, a (1-4C) alkoxy group optionally substituted with at least one fluoro atom, and a halogen atom; R3 is selected from the group consisting of a (1-4C)alkylene-R6 group wherein the alkylene group may be substituted with (CH R4 is selected from the group consisting of H and a (1-4C)alkyl group; R5 is at least one substituent wherein each substituent is independently selected from the group consisting of H, a (1-4C)alkyl group, and an oxo group; and W is selected from the group consisting of —O—, —S—, —SO—, and —SO with the proviso that the compound of formula (I) is not 2-[4-(4-chlorophenoxy)-2-chloro-phenyl]-4-morpholineethanol.