Patent ID: 9745603
Date: 2017-08-29
CPC Classifications: C12N,C12P,C12Y,Y02E

Claim:
1. A genetically modified methanotroph that is capable of producing 2,3-butanediol from methane (CH 4 ), the genetically modified methanotroph comprising exogenous polynucleotides encoding acetolactate synthase and 2,3-butanediol dehydrogenase, wherein the acetolactate synthase has acetolactate synthase activity and comprises an amino acid sequence having at least 90% sequence homology to SEQ ID NO:2, and the 2,3-butanediol dehydrogenase has 2,3-butanediol dehydrogenase activity and comprises an amino acid sequence having at least 90% sequence homology to SEQ ID NO: 157, wherein said methanotroph is capable of converting methane to pyruvate through an endogenous type I RuMP pathway or a type II serine pathway.