Patent ID: 9707323
Date: 2017-07-18
CPC Classifications: A61L

Claim:
1. An implantable device for reducing or preventing adhesion formation at a post-operative tissue site in a patient, the implantable device comprising a biodegradable porous polymer matrix comprising dextran sulfate, wherein the implantable device is configured to release the dextran sulfate over a period of at least 2 days, and the matrix is in a sponge form comprising poly(L-lactide-co-D, L-lactide) and having a density of between about 1.6 g/cm 3 and about 0.3 g/cm 3 , and a core comprising dense entangled polymers of the implantable device does not contain dextran sulfate, and the matrix comprises an initial burst release surface disposed on edges of the matrix that releases 20% to 25% of dextran sulfate over 24 hours, and the average sulfur content of the dextran sulfate is 16% to 19%.