Patent ID: 9649362
Date: 2017-05-16
CPC Classifications: A61K,A61P,C07K

Claim:
1. A peptide conjugate or pharmaceutically acceptable salt thereof having the formula wherein R R Z wherein Z9 is selected from Asp and Glu; Z12 is selected from Lys, Arg and Orn; Z13 is selected from Gln and Tyr; Z14 is selected from Met and Leu; Z16 is selected from Glu, Cys and Lys; Z20 is selected from Arg, Lys and Orn; Z24 is selected from Lys and Glu; Z25 is selected from Trp, Lys, Cys and Phe; Z27 is selected from Lys, Arg and Orn; Z28 is selected from Asn and Asp or is absent; L is a peptide sequence having the formula IIIb wherein L1 is selected from Peg3, Gln, Cys, Lys and Orn or is absent; L2 is selected from Peg3, Gln, Cys, Lys and Orn or is absent; L3 is selected from Peg3, Gln, Cys, Lys and Orn or is absent; L4 is selected from Peg3, Gln, Cys, Lys and Orn or is absent; Y wherein Y12 is selected from Tyr and Ala or is absent; Y13 is selected from Gly and Ala or is absent; Y14 is selected from Trp, 1Nal and Phe; Y15 is selected from Leu, Nle, Thr and Phe; and Y17 is selected from Phe and 3-(3-Pyridyl)-alanine.