Patent ID: 9643946
Date: 2017-05-09
CPC Classifications: A61P,C07C,C07D

Claim:
1. A compound selected from the group consisting of a tricyclic compound of Formula I, and a pharmaceutically acceptable salt, isomer, and solvate thereof: wherein V and W are each independently ═C(R X is —CH Y is a C Z is —O—, —S—, —C(═O)—, —S(═O)—, —S(═O) Ar is one of the following substituents (a) to (c), wherein A is —CH B is a C R R R R R R R R R n, o, and p are each independently 0, 1, 2, or 3; provided that the alkylene, the alkyl, the akenyl, the alkynyl, the alkoxy, the alkylthio, the amino, the acyl, the alkylsulfonyloxy, the carbocyclyl, the carbocyclyloxy, the carbocyclylsulfonyloxy, the heterocyclyl, the heterocyclyloxy, and the heterocyclylsulfonyloxy may each independently be substituted with at least one substituent selected from the group consisting of a 4- to 7-membered heterocyclyl (unsubstituted or substituted with 1 to 3 substituents selected from the group consisting of hydroxy, a halogenated C the heterocyclyl contains 1 to 4 heteroelements selected from the group consisting of N, O, S, S(═O), and S(═O)