Patent ID: 9701942
Date: 2017-07-11
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method for preparing antigen-specific dendritic cells comprising: (a) pulsing immature dendritic cells with an antigen; (b) maturing the dendritic cells by treating the dendritic cells with at least one maturation factor selected from the group consisting of Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Tumor necrosis factor-α (TNF-α), Interferon gamma (IFN-γ), Prostaglandin E2 (PGE2), and Poly IC; and (c) maturing the dendritic cells by treating the dendritic cells with Picibanil (OK432) 4 to 30 hours after steps (a) and (b).