Patent ID: 9637523
Date: 2017-05-02
CPC Classifications: A61K,A61P,C07K,C12N,C12Q,C12Y,G01N

Claim:
1. A method of treating a BCR-ABL associated disease or a c-ABL associated disease selected from the group consisting of chronic myeloid leukaemia (CML), acute lymphatic leukaemia (ALL), acute myeloic leukaemia (AML) and a c-ABL associated leukemia in a subject in need thereof, the method comprising administering to the subject a nonstructural protein 1 (NS1), wherein the NS1 protein comprises the amino acid sequence of SEQ ID NO: 1 and PPX 13 PX 1 X 16 (SEQ ID NO: 107), wherein X 1 is any amino acid, X 13 is selected from the group consisting of A, C, G, I, L, M, F, P, W and V, and X 16 is K or R.