Patent ID: 9694338
Date: 2017-07-04
CPC Classifications: B01J,G01N

Claim:
1. A method of preparing a hydrogel array comprising a multi-well plate, the multi-well plate comprising a plurality of wells wherein the plurality of wells independently comprises a hydrogel post, the method comprising thiol-functionalizing a bottom surface of the plurality of wells; adding a hydrogel precursor solution to at least one well of the plurality of wells; selectively polymerizing a portion of the hydrogel precursor solution in the at least one well; removing unpolymerized hydrogel precursor solution from the plurality of wells, wherein the polymerized hydrogel forms a hydrogel post covalently immobilized within the at least one well and wherein the hydrogel post is surrounded by a hydrogel-free background; and forming an additional hydrogel layer on the hydrogel post.