Patent ID: 9650427
Date: 2017-05-16
CPC Classifications: A61K,A61P,C07K

Claim:
1. An inhibitor of antiviral RIG-I like receptors (RLRs) activity comprising a polypeptide fragment of SEQ ID NO: 4, wherein the polypeptide fragment of SEQ ID NO: 4 is a fragment selected from the group consisting of residues 10-77 of SEQ ID NO: 4, residues 15-77 of SEQ ID NO: 4, residues 20-77 of SEQ ID NO: 4, residues 25-77 of SEQ ID NO: 4, residues 30-77 of SEQ ID NO: 4, residues 35-77 of SEQ ID NO: 4, residues 40-77 of SEQ ID NO: 4, residues 45-77 of SEQ ID NO: 4, residues 50-77 of SEQ ID NO: 4, residues 10-73 of SEQ ID NO: 4, residues 15-73 of SEQ ID NO: 4, residues 20-73 of SEQ ID NO: 4, residues 25-73 of SEQ ID NO: 4, residues 30-73 of SEQ ID NO: 4, residues 35-73 of SEQ ID NO: 4, residues 40-73 of SEQ ID NO: 4, residues 45-73 of SEQ ID NO: 4 and residues 50-73 of SEQ ID NO: 4, and a covalently linked moiety that facilitates delivery of the inhibitor to the cytosol of a cell.