Patent ID: 9744155
Date: 2017-08-29
CPC Classifications: A61K,A61P,G01N

Claim:
1. A method for evaluating oxidative stress in an individual known to be suffering from a disease, comprising obtaining a biological sample from said individual, subjecting the biological sample to a Fenton reaction in the presence of ubiquitin, using LC-EC and MS, analyzing said reacted biological sample for the presence of an oxidation product of indole-3-propionic acid bound to ubiquitin, an oxidation product of indole lactic acid bound to ubiquitin, or a ratio of an oxidation product of indole-3-propionic acid bound to ubiquitin/an oxidation product of indole lactic acid bound to ubiquitin, and comparing said analysis to a standard from an individual known to be suffering from said disease.