Patent ID: 9717740
Date: 2017-08-01
CPC Classifications: A23L,A23V,A61K,A61P

Claim:
1. A method for treating adrenal insufficiency in a pediatric or elderly human in need thereof, the method comprising: orally administering to the human an oral dosage form comprising a plurality of hydrocortisone-containing multilayer microparticles, wherein each of the hydrocortisone containing multilayer microparticles comprises: (i) an inert core consisting essentially of microcrystalline cellulose; (ii) a sealing layer consisting of hydroxypropyl methyl cellulose and magnesium stearate; (iii) an active agent layer between the inert core and the sealing layer, the active agent layer comprising hydrocortisone and hydroxypropyl methylcellulose; and (iv) an exterior layer for taste-masking comprising hydroxypropyl methylcellulose and ethyl cellulose; and wherein the plurality of hydrocortisone-containing multilayer microparticles collectively comprises a therapeutically effective amount of hydrocortisone.