Patent ID: 9566322
Date: 2017-02-14
CPC Classifications: A61K,A61P,C12Q,G01N

Claim:
1. A pharmaceutical composition comprising: (i) (a) a polypeptide encoded by SACOL0442 comprising residues 36 to 203 of the amino acid sequence of SEQ ID NO: 37 or SEQ ID NO: 48; (b) a polypeptide comprising an amino acid sequence at least 95% identical overall to the polypeptide of (a), and comprising one or more of the following amino acid sequences: KDTINGKSNKSRNW (SEQ ID NO: 18) or KDGGKYTLESHKELQ (SEQ ID NO: 19); (c) a polypeptide comprising an immunogenic fragment of at least 14 consecutive amino acids of (a), and comprising one or more of the following amino acid sequences: KDTINGKSNKSRNW (SEQ ID NO: 18) or KDGGKYTLESHKELQ (SEQ ID NO: 19); or (d) any combination of (a) to (c), wherein said polypeptide has the ability to elicit an immune response in a mammal; (ii) (a) a polypeptide encoded by SACOL0720 comprising residues 309 to 508 of the amino acid sequence of SEQ ID NO: 62 or SEQ ID NO: 74; (b) a polypeptide comprising an amino acid sequence at least 95% identical overall to the polypeptide of (a), and comprising one or more of the following amino acid sequences: QFGFDLKHKKDALA (SEQ ID NO: 20), TIKDQQKANQLAS (SEQ ID NO: 21), KDINKIYFMTDVDL (SEQ ID NO: 22) or DVDLGGPTFVLND (SEQ ID NO: 23); (c) a polypeptide comprising an immunogenic fragment of at least 13 consecutive amino acids of (a), and comprising one or more of the following amino acid sequences: QFGFDLKHKKDALA (SEQ ID NO: 20), TIKDQQKANQLAS (SEQ ID NO: 21), KDINKIYFMTDVDL (SEQ ID NO: 22) or DVDLGGPTFVLND (SEQ ID NO: 23); or (d) any combination of (a) to (c), wherein said polypeptide has the ability to elicit an immune response in a mammal; and (iii) an adjuvant.