Patent ID: 9597388
Date: 2017-03-21
CPC Classifications: A61K,A61N,A61P,C07K,C12N

Claim:
1. A composition comprising a nucleic acid sequence that encodes a consensus Zaire ebolavirus envelope glycoprotein immunogen, the amino acid sequence of the consensus Zaire ebolavirus envelope glycoprotein immunogen selected from the group consisting of: SEQ ID NO:1, a fragment of SEQ ID NO:1 that comprises 600 or more contiguous amino acids, an amino acid sequence that is at least 99.5% identical to SEQ ID NO:1, a fragment of an amino acid sequence that is at least 99.5% identical to SEQ ID NO:1 that comprises 600 or more contiguous amino acids; SEQ ID NO:1 linked to an IgE signal peptide, a fragment of SEQ ID NO:1 that comprises 600 or more contiguous amino acids linked to an IgE signal peptide, an amino acid sequence that is at least 99.5% identical to SEQ ID NO:1 linked to an IgE signal peptide, and a fragment of an amino acid sequence that is at least 99.5% identical to SEQ ID NO:1 that comprises 600 or more contiguous amino acids linked to an IgE signal peptide.