Patent ID: 9675593
Date: 2017-06-13
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method of treating a fibrotic condition selected from pulmonary fibrosis, dermal fibrosis, pancreatic fibrosis, liver fibrosis, and renal fibrosis, comprising administering a therapeutically effective amount of a compound having the structure of Formula (III): or a pharmaceutically acceptable salt thereof to a subject in need thereof, wherein R R ring A is optionally substituted with one or more R 4 , wherein R 17 is independently selected from hydrogen, optionally substituted C 1-6 alkyl, optionally substituted C 3-6 cycloalkyl, optionally substituted C 2-8 alkoxyalkyl, optionally substituted C-carboxy, acyl, C 6-10 aryl optionally substituted with one or more R 11 , or C 7-14 aralkyl optionally substituted with one or more R 11 , each R each R each R each R each R each R each R each R R R each R Z is selected from oxygen and sulfur; each n is 0; and the bonds represented by a solid and dashed line are independently selected from the group consisting of a single bond and a double bond.