Patent ID: 9708286
Date: 2017-07-18
CPC Classifications: A61K,A61P,C07C,C07D

Claim:
1. A compound of the general formula I wherein R is heterocycloalkyl or heterocycloalkenyl, wherein said heterocycloalkyl or heterocycloalkenyl are optionally substituted by one or more substituents independently selected from R8; or R is X; R8 represents halogen, cyano or hydroxyl; or R8 represents (C or R8 represents —NRaCORb, —COORc, —OCORa, —CONRaRb, —OCONRaRb, —NRaCOORb, —NRaCONRaRb, —NRaSO2NRaRb, —NRaSO2Rb, —SO2NRaRb, —SO2Ra, —S(O)Ra, —ORa, —SRa, ═O, ═N—ORa, —O—N═CRaRb, NRaRb or —C(O)N(Ra)O—Rb; R10 represents halogen, cyano, hydroxy, (C Ra and Rb represent hydrogen, (C Rc represents hydrogen, (C X represents —NR11R12; wherein R11 and R12 independently represent hydrogen, or wherein R11 and R12 independently represents (C R13 represents halogen, cyano or hydroxyl, or R13 represents (C or R13 represents —NRdCORe, —COORf, —OCORd, —CONRdRe, —OCONRdRe, —NRdCOORe, —NRdCONRdRe, —NRdSO2Re, —NRdSO2NRdRe, —SO2NRdRe, —SO2Rd, —S(O)Rd, —ORd, —SRd, ═O, ═N—ORd, —O—N═CRdRe, —NRdRe or —C(O)N(Rd)—ORe wherein Rd and Re independently represents hydrogen, (C Rf represents hydrogen, (C R14 represents halogen, hydroxyl, cyano, (C pharmaceutically acceptable salts, hydrates and solvates thereof.