Patent ID: 9693950
Date: 2017-07-04
CPC Classifications: A61K,A61M

Claim:
1. A method of forming a coated microneedle array comprising providing a microneedle array comprising a microneedle substrate and a plurality of microneedles; providing a coating substrate; providing an aqueous formulation comprising at least one active pharmaceutical ingredient and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100 s applying the aqueous formulation to the coating substrate; bringing the aqueous formulation and the microneedles of the microneedle array into contact with one another; removing the microneedles from the aqueous formulation; and allowing at least a portion of the aqueous formulation to evaporate, wherein the aqueous formulation has a contact angle on a medical grade polymeric material of 50° or greater and 96° or less when measured under ambient conditions.