Patent ID: 9689039
Date: 2017-06-27
CPC Classifications: C12Q,G01N

Claim:
1. A method for diagnosing the presence of lung cancer in a subject at risk of having lung cancer, the method comprising: a) contacting a saliva sample from the subject with a set of at least three reagents, wherein the set of at least three reagents specifically binds to at least three biomarkers in the saliva sample, wherein the three biomarkers are selected from the group consisting of BRAF, EGFR, FGF19, LZTS1, CCNI, GREB1, and FRS2; b) measuring the level of the at least three biomarkers in the saliva sample; c) detecting that the level of the at least three biomarkers is increased in the saliva sample relative to a control sample from a subject without lung cancer, thereby detecting the presence of lung cancer in the subject; and d) administering a lung cancer therapy to the subject, wherein the lung cancer therapy is selected from the group consisting of chemotherapy, hormonal therapy, radiotherapy, immunotherapy, and surgical removal of lung tissue.