Patent ID: 9593323
Date: 2017-03-14
CPC Classifications: A61K,A61P,C07K,C12N,C12Y,G01N

Claim:
1. An isolated polynucleotide that encodes an aminoacyl-tRNA synthetase (AARS) polypeptide which consists of a sequence that is at least 95% identical to SEQ ID NO:45, 43, 19, or 12, or a fragment thereof which is 120 or more contiguous amino acids of SEQ ID NO: 45, 43, 19, or 12, wherein the AARS polypeptide has an extracellular signaling activity, and wherein the polynucleotide is selected from (a) a cDNA polynucleotide and (b) a modified mRNA polynucleotide.