Patent ID: 9683993
Date: 2017-06-20
CPC Classifications: B01L,G01N

Claim:
1. A method of measuring a light transmittance signal through a metallic layer comprising: carrying out a chemical and/or biological reaction in a meandering region of a microfluidic channel by allowing a sample component to bind with a binding partner disposed on a surface of the microfluidic channel in the meandering region, wherein a catalytic metal colloid is associated with the sample component; flowing a metal solution over the surface wherein the metal solution reacts with the catalytic metal colloid to form the metallic layer; exposing the meandering region to light; and measuring the light transmittance signal through the metallic layer of more than one adjacent segments of the microfluidic channel in the meandering region, wherein the more than one adjacent segments are separated by at least one turn of greater than 135 degrees.