Patent ID: 9567344
Date: 2017-02-14
CPC Classifications: A61K,A61P,C07D

Claim:
1. A composition comprising a pharmaceutical agent, wherein the pharmaceutical agent has a solubility of 33 mg/mL to less than 0.1 mg/mL in an aqueous solvent, wherein the pharmaceutical agent is non-covalently complexed to a compound having the following structure: or a salt, a partial salt, a hydrate, or a stereoisomer thereof, wherein each R is independently hydrogen, C wherein, optionally, adjacent R groups form a C wherein each is independently a C 5 to C 20 carbocyclic ring system or C 2 to C 20 heterocyclic ring system, wherein the ring system comprises one or more rings; wherein at least one ring system has at least one solubilizing group selected from sulfonic acid group, sulfonate salt group, phosphonic acid group, phosphonate salt group, and polyethylene glycol group; wherein, optionally, the ring system has a targeting group; wherein n is 1 to 5.