Patent ID: 9547013
Date: 2017-01-17
CPC Classifications: G01N

Claim:
1. A method of detecting levels of cellular metabolites in an individual suspected of having autism, the method comprising the steps of: (a) obtaining a biosample comprising brain tissue from an individual; (b) detecting levels of a plurality of cellular metabolites in the biosample using liquid chromatography electro spray-ionization time of flight mass spectrometry, wherein the cellular metabolites are selected from N-acetylaspartylglutamic acid, 2-aminooctanoic acid, 5-hydroxylysine, vinylacetylglycine, proline, betaine, 3-carboxy-1-hydroxypropylthiamine diphosphate, 3′-sialyllactosamine, 3,4-dihydroxybenzylamine, dipalmitoyl-phosphatidylcholine, and SAICAR ((S)-2-[5-Amino-1-(5-phospho-D-ribosyl) imidazole-4-carboxamido]succinate).