Patent ID: 9540301
Date: 2017-01-10
CPC Classifications: A61K,A61P,C07C,C07F

Claim:
1. A method for manufacturing a compound of Formula (III), the method comprising: reacting a compound of Formula (I) with a compound of Formula (II) to obtain a reaction product; and contacting the reaction product with (i) at least one acid selected from the group consisting of hydrochloric acid, sulfuric acid, nitric acid, phosphoric acid, nitrous acid, trifluoroacetic acid, oxalic acid, formic acid, acetylacetic acid, lactic acid, succinic acid, benzoic acid, adipic acid, acetic acid, and propionic acid, or (ii) a base, thereby obtaining the compound of Formula (III), wherein each R R X is a halogen atom.