Patent ID: 9668968
Date: 2017-06-06
CPC Classifications: A61K,A61L,B29C,B29K,B29L,B33Y

Claim:
1. A multi-step method of forming a plurality of mammalian subcutaneous medical implants, each implant comprising a matrix core, a coating, and at least one opening through which the implant releases one or more biodegradable drugs on a controlled basis over at least a 3 day period, wherein the method comprises: supplying a sheet of prefabricated coating material prior to the depositing, multiple depositing steps for depositing in one or more enclosed chambers at least portions of one or more individual layers of the implant by at least one computer controlled 3-D printer, wherein at least one portion of said one or more layers is an impermeable coating layer, wherein the depositing by the 3-D printer occurs on the sheet of prefabricated coating material, forming said matrix core and the remainder of said coating during said depositing steps, forming said at least one opening in said at least one impermeable coating layer so as to permit the release of said drugs to the environment outside of said implant, wherein said matrix core comprises said one or more drugs, wherein said coating surrounds at least a part of said matrix core, and thereby forming the plurality of implants at the same time during the same 3-D depositing step.