Patent ID: 9580739
Date: 2017-02-28
CPC Classifications: A61K,A61P,C12Q,C12Y,G01N

Claim:
1. A method of treatment of an asparaginase-sensitive pathology in a patient, said methods comprising: (a) obtaining a sample of blood, plasma, or serum from a patient; (b) incubating said sample with a known amount of asparaginase for a period of time sufficient to produce antibody-asparaginase immune complexes; (c) removing from the incubated sample any antibody-asparaginase immune complexes formed during incubation step (b) and recovering a sample free of antibody-asparaginase immune complexes; (d) incubating the sample obtained at step (c) with asparagine; (e) determining a residual asparaginase activity or the amount of asparaginase residual activity in the resultant mixture of step (d); and (f) treating said patient by means of the asparaginase and/or by means of another form of asparaginase.