Patent ID: 9585844
Date: 2017-03-07
CPC Classifications: A61K,A61P

Claim:
1. An oral composition comprising minicapsules wherein the minicapsules comprise an active pharmaceutical in a liquid, semi-solid or solid core, the minicapsules having release profiles to release the active pharmaceutical in an active form in the colon and the minicapsules comprising a gelling agent encapsulating the active pharmaceutical selected from solubilised active pharmaceutical and dispersed active pharmaceutical, and combinations thereof, and the minicapsules being coated to target release to the colon, and the active pharmaceutical being selected from: an antigen with an adjuvant; antigenic, and optionally covalently or non-covalently modified, peptides, in combination with an adjuvant and/or permeability enhancer; a kappa B alpha (IKκBα) kinase inhibitor and/or covalent or non-covalent derivatives thereof; nicotine and/or derivatives thereof; a COX-II inhibitor; one or a combination of insulin sensitizers, sulphonamides, glucagon-like peptides; TNFα inhibitors; NFκβ inhibitors; or a combination thereof.