Patent ID: 9624161
Date: 2017-04-18
CPC Classifications: A61K,C07C,C07D

Claim:
1. A method of treating, suppressing, reducing the incidence of, reducing the severity of, or inhibiting the progression of castration resistant prostate cancer (CRPC) and its symptoms, or increasing the overall or progression-free survival of men with castration resistant prostate cancer (CRPC) comprising administering a therapeutically effective amount of a compound of formula I, or its isomer, pharmaceutically acceptable salt, pharmaceutical product, polymorph, hydrate or any combination thereof: wherein Y is C(O) or CH R R R is alkyl, hydrogen, haloalkyl, dihaloalkyl, trihaloalkyl, CH R j and k are each independently 1-4; and Alk is a linear alkyl of 1-7 carbons, a branched alkyl of 1-7 carbons, or a cyclic alkyl of 3-8 carbons.