Patent ID: 9574004
Date: 2017-02-21
CPC Classifications: A61K,A61P,C07K,C12Q,G01N

Claim:
1. A method for the treatment of persistent asthma that reduces the incidence of asthma exacerbations or improves one or more asthma-associated parameter(s) in a subject with persistent asthma comprising sequentially administering to the subject a single initial dose of a pharmaceutical composition comprising an antibody or an antigen-binding fragment thereof, wherein the antibody or antigen-binding fragment thereof specifically binds an interleukin-4 receptor (IL-4R), and wherein administration of the single initial dose is followed by one or more secondary doses of the pharmaceutical composition comprising the antibody or antigen-binding fragment thereof, wherein the antibody or antigen-binding fragment thereof comprises heavy chain and light chain complementarity determining region (CDR) sequences from a heavy chain variable region (HCVR)/light chain variable region (LCVR) sequence pair of SEQ ID NOs: 162/164.