Patent ID: 9701675
Date: 2017-07-11
CPC Classifications: A01K,A61K,A61P,C07D,C07K,G01N

Claim:
1. A method of treating a dermatological disorder in a subject in need thereof, the method comprising administering to the subject an effective amount of a TRPV4 inhibitor, the dermatological disorder is selected from the group consisting of inflammation, skin pain, itch, non-melanoma skin cancer, autoimmune diseases, fibrotic diseases, and skin pigmentation, and wherein the TRPV4 inhibitor comprises a compound according to Formula I: wherein A is selected from the group consisting of phenyl and pyridnyl; B and C are phenyl; D is C E is a bond or C R is selected from the group consisting of hydrogen, hydroxyl, amino, alkyl, and alkenyl.