Patent ID: 9610362
Date: 2017-04-04
CPC Classifications: A61J,A61K,A61P,C07K,C12N,C12Y

Claim:
1. A conjugate comprising a) an antisense oligonucleotide that hybridizes to a DMPK transcript wherein the oligonucleotide is capable of: b) an antibody or antigen binding fragment: wherein the antibody or antigen binding fragment comprises a heavy chain variable domain that is at least 95% identical to the amino acid sequence of SEQ ID NO: 13, or a humanized variant thereof, and a light chain variable domain that is at least 95% identical to the amino acid sequence of SEQ ID NO: 14, or a humanized variant thereof; wherein the antibody or antigen binding fragment promotes delivery of the antisense oligonucleotide into muscle cells.