Patent ID: 9617213
Date: 2017-04-11
CPC Classifications: C07C,C07D

Claim:
1. Compounds of general formula (i): wherein: R n is an integer ranging from 1 to 5; A is a monocyclic or bicyclic aryl, or an aromatic or non-aromatic heterocyclic ring selected from the group consisting of pyrrole, pyrrolidine, 3-pyrroline, 2H-pyrrole, 2-pyrroline, indole, isoindole, 3H-indole, indolizine, indoline, carbazole, furan, benzofuran, isobenzofuran, 2H-pyran, 4H-pyran, benzo[b]thiophene, thiophene, pyridine, piperidine, 4H-quinolizine, isoquinoline, quinoline, tetrahydroquinoline, 1,8-naphthyridine, acridine, oxazole, isoxazole, benzoxazole, benzothiazole, isothiazole, thiazole, imidazole, 2-imidazole, imidazolidine, tetrazole, 1,2,3-triazole, 1,2,4-triazole, 1,2,3-oxadiazole, benzimidazole, purine, 1,4-dioxane, 1,3-dioxolane, 1,3-dithiane, 1,4-dithiane, 1,3,5-trithiane, morpholine, thiomorpholine, phenothiazine, pyrazole, 2-pyrazoline, pyrazolidine, quinazoline, cinnoline, pyrimidine, pyrazine, pteridine, phthalazine, 1,2,4-triazine, 1,3,5-triazine, pyridazine, piperazine, quinoxaline, phenazine, 1H-indazole, wherein the substituents on ring A, independently from each other, are selected from the group consisting of H, —O-alkyl, —OCH provided that the compound of general formula (i) is not: (E)-3-phenyl-1-(2,4,6-trimethoxy-3-(3-methylbut-2-enyl)phenyl)prop-2-en-1-one; or (E)-3-phenyl-1-(2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl)prop-2-en-1-one; tautomers, pharmaceutically acceptable salts and pro-drugs thereof.