Patent ID: 9743020
Date: 2017-08-22
CPC Classifications: G01N,G02B,G06T,H04N

Claim:
1. A super resolution optofluidic microscope device, comprising: a multi-layer body comprising a micromolded microfluidic chip fabricated using micro/nanofabrication procedures, the micromolded microfluidic chip defining a fluid channel having a longitudinal axis; an image sensor, wherein the micromolded microfluidic chip is affixed directly to the image sensor during fabrication such that the image sensor is oriented with its local axis at an angle from the longitudinal axis of the fluid channel, wherein during operation the image sensor receives light passing through an object being imaged while the object is moving through the fluid channel and samples a sequence of subpixel shifted two-dimensional projection images of the object as it moves through the fluid channel; and a processor in electronic communication with the image sensor to receive data during operation that comprises the sampled sequence of subpixel shifted two-dimensional projection images of the object, wherein during operation the processor generates a high resolution two-dimensional image of the object from the sampled sequence of subpixel shifted two-dimensional projection images and a motion vector of the object using a super resolution algorithm.