Patent ID: 9562068
Date: 2017-02-07
CPC Classifications: C07J

Claim:
1. A process for the production of 7α-(methoxycarbonyl)-3-oxo-17α-pregn-4-9(11)-dien-21,17-carbolactone (V) comprising elimination of a molecule of water from 11α-hydroxy-7α-(methoxycarbonyl)-3-oxo-17α-pregn-4-en-21,17-carbolactone (IV) by reaction with a two component mixture (VI) consisting of (Et) 2 NCF 2 CHFCF 3 and (Et) 2 NFC═CFCF 3 , wherein quantities of the two components of said mixture (VI) are variable in ratios such that an observed area of a minority component is not less than 75% than an observed area of a majority component as determined in a gas chromatographic analysis.