Patent ID: 9656003
Date: 2017-05-23
CPC Classifications: A61F,A61L

Claim:
1. A method of manufacturing a coated medical device comprising an implantable structure having a coated surface extending from a proximal end to a distal end, the method comprising: spraying first droplets of a solution having a first average liquid droplet size onto a first region of the surface, wherein the solution comprises a first therapeutic agent dissolved in a volatile solvent; evaporating the volatile solvent from the first region to form a coating of the first therapeutic agent on the first region; spraying second droplets of the solution having a second average liquid droplet size onto a second region of the surface; evaporating the volatile solvent from the second region to form a coating of the first therapeutic agent on the second region, wherein the first average droplet size differs from the second average droplet size and wherein the first therapeutic agent elutes at a different rate from the first region than from the second region when the first and second regions are implanted in the vascular system of a subject.