Patent ID: 9694128
Date: 2017-07-04
CPC Classifications: A61M

Claim:
1. A method of administering anti-cancer antibodies to a patient, comprising the steps of establishing an in line and ex vivo connection between the patient and a chamber containing the anti-cancer antibodies, said chamber comprising a plurality of parallel aligned polymeric micro tubules providing interior multiple surfaces to which individual antibodies are attached at points of attachment, said individual antibodies including Fc receptors that are oriented so the Fc receptors on individual antibodies are remote from their points of attachment to enable the Fc receptors to bind to the immune cells in the patient's blood, withdrawing blood from the patient into the chamber so that immune cells in the patient's blood flowing through the chamber are treated by the anti-cancer antibodies, said chamber providing an internal surface structure to which the anti-cancer antibodies are attached, said internal surface structure comprising a polymeric material that interacts with immune cells to stimulate effector cell functions, said blood flowing through the chamber and being returned to the patient without disconnection from the chamber, and after treating the patient's blood and returning to the patient the patient's blood including the treated immune cells, terminating the connection, said chamber having a pair of spaced apart ports, one port being adapted to be connected to the patient to enable blood to be withdrawn from the patient and flow into the chamber and be mixed with the anti-cancer antibodies in the chamber and the other port being adapted to enable the treated blood in the chamber to be returned to the patient, the patient's blood being retained in the chamber from 10 to 90 minutes and repeated periodically from 1 to 3 times per week with treatment intervals of from 1 to 2 days, whereby the immune cells in the blood contact and interact with the anti-cancer antibodies.