Patent ID: 9688989
Date: 2017-06-27
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method for treating tinnitus in a subject, comprising administering to the subject an inhibitor of Histamine type 4 receptor (H4R), wherein said inhibitor of Histamine type 4 receptor (H4R) has a Ki(H3)/Ki(H4) ratio above 10, and wherein said inhibitor of Histamine type 4 receptor (H4R) is selected from the group consisting of 2-aminopyrimidine derivatives, pyrimidine derivatives, quinazoline derivatives, quinazoline sulfonamide compounds, bicyclic heteroaryl-substituted imidazole compounds, thieno-pyrimidine compounds, furo-pyrimidine compounds and mequitazine compounds.