Patent ID: 9636333
Date: 2017-05-02
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method for treating a condition in a subject comprising: administering to the subject a therapeutically effective amount of a p38 inhibitor of a compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein: X is CH or N; R R R R R m is 1 or 2; n is 0 or 1; p is 1; and q is 0 or 1; wherein the condition is amenable to inhibition of p38 and said condition is selected from the group consisting of ulcerative colitis, inflammatory bowel disease, Crohn's disease, psoriasis, systemic lupus erythematosus, multiple sclerosis, Grave's disease, myasthenia gravis, chronic inflammatory disorders, acute inflammatory disorders, auto-inflammatory disorders, bone disorders, osteoarthritis, septic shock, endotoxic shock, endotoxin-induced toxic shock, toxic shock syndrome, sepsis, atherosclerosis, diabetes, rheumatoid arthritis, osteoarthritis, arthritis, asthma, inflammatory bowel disease, ulcerative colitis, Crohn's disease, reperfusion injury, neuronal ischemia, stroke, chronic gout, graft versus host disease, allograft rejection, psoriasis, glomerulonephritis, pulmonary inflammation, lymphoma, metastatic melanoma, multiple myeloma, and chronic obstructive pulmonary disease (COPD), and fibrotic diseases.