Patent ID: 9572880
Date: 2017-02-21
CPC Classifications: A61B,A61K,A61M,A61N,A61Q,B82Y

Claim:
1. A method of delivering a composition to a target tissue under a skin surface with a delivery device and performing ablation, comprising: applying a composition to a skin surface, distributing the composition from the skin surface to a target tissue under the skin surface with a delivery device, wherein the delivery device is an ultrasound device; wherein said composition comprises a plurality of unassembled plasmonic nanoparticles, wherein the unassembled plasmonic nanoparticles comprise a conductive metal portion, wherein the conductive metal portion comprises at least one of gold or silver, wherein the unassembled plasmonic nanoparticles have a size one in a range of 10 nm to 300 nm wherein the unassembled plasmonic nanoparticles comprise a coating that coats the conductive metal portion, wherein said coating facilitates selective removal from the skin surface; wherein the coating comprises at least one of silica or polyethylene glycol (PEG), wherein the unassembled plasmonic nanoparticles have a concentration suitable for application to the skin surface, wherein said concentration is at least 10 selectively removing the composition from the skin surface, while leaving the composition localized within the sebaceous gland; and irradiating the composition with an infrared light source thereby inducing a plurality of surface plasmons in said unassembled plasmonic nanoparticles, wherein inducing the plurality of surface plasmons generates localized heat for ablation in the target tissue.