Patent ID: 9701676
Date: 2017-07-11
CPC Classifications: A61K,A61P,C07D

Claim:
1. A method of treating a neuropsychiatric or neurodegenerative disease, disorder, or condition, the method comprising administering to a subject in need thereof an effective amount of a compound having formula (III), or a pharmaceutically acceptable salt thereof: wherein R 1b is selected from the group consisting of: hydrogen; C 1-6 alkyl optionally substituted with one or more halo, hydroxyl, cyano and/or azide; —CH(R 5 )—C(O)—Z 1b ; and —CH 2 —C(R A1 )(R A2 )—CH 2 —Z 2b ; wherein R wherein Z wherein one of R wherein Z wherein R 3b and R 4b are each independently selected from the group consisting of: hydrogen, halo, hydroxyl, C 1-3 alkoxyl, cyano, carboxyl, and formamide; wherein the disease, disorder, or condition is selected from one or more of schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of neuro-active drugs, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss, and cognitive decline associated with normal aging, radiation therapy, and chemotherapy.