Patent ID: 9556412
Date: 2017-01-31
CPC Classifications: B01L,C12M

Claim:
1. A method of separating cells from a fluid sample under the influence of a force, comprising: receiving a fluid through a centrally located top inlet of a plenum, the plenum having a diminishing volume in a direction of the force with a first cross-sectional area proximate the inlet larger than a second cross-sectional area proximate a bottom outlet of the plenum; directing the fluid toward the bottom outlet disposed below the top inlet, the fluid directed against respective side-walls of the plenum, the side walls each extending at an acute angle with respect to the direction of the force and positioned to the side of the inlet and the bottom outlet; and flowing the fluid in the plenum under the force, the plenum having a distance between each of two or more side outlets and the bottom outlet, the distance selected such that cells in the fluid exit through the bottom outlet under the force while a non-cell portion of the fluid exits through the two or more side outlets above the bottom outlet.