Patent ID: 9664689
Date: 2017-05-30
CPC Classifications: C07K,G01N

Claim:
1. A method for detecting procalcitonin 1-116 (SEQ ID NO: 1) and N-terminal procalcitonin peptides comprising amino acids alanine and proline (Ala-Pro or AP) in positions 1 and 2 of the amino terminus of procalcitonin 1-116 (SEQ ID NO: 1) in a sample, the method comprising contacting said sample with an antibody that specifically binds an epitope of procalcitonin 1-116 comprising amino acids 1 and 2 of procalcitonin 1-116 and binds selectively to intact procalcitonin 1-116 (SEQ ID NO: 1) or procalcitonin partial peptides comprising amino acids 1 and 2 of SEQ ID NO: 1, said antibody comprising a detectable label or being detectable by a molecule comprising a detectable label; and detecting the concentration of procalcitonin 1-116 and N-terminal procalcitonin peptides comprising amino acids alanine and proline (Ala-Pro or AP) in positions 1and 2 of the amino terminus of procalcitonin 1-116 in said sample by measuring the amount of bound detectable label in said sample.