Patent ID: 9643986
Date: 2017-05-09
CPC Classifications: A61K,A61P,C07B,C07D,C07F

Claim:
1. A compound of formula or a pharmaceutically acceptable salt thereof, wherein Q Q Q X R (a) hydrogen, halogen, hydroxyl, nitro, cyano, amino, C (b) —C Additionally any one of the following rings (c), (d), (e), (f), (g), or (h) may be present: (c) R (d) R (e) R (f) R (g) R (h) R A is a heterocyclic group chosen from: R (i) —CHO, —C(O)NH (j) hydrogen, hydroxyl, halogen, cyano, nitro, —COOH, —SO each R R R R R R R (k) hydrogen, halogen, hydroxyl, nitro, cyano, amino, —COOH, C (l) C (m) —C where J is independently chosen at each occurrence from a covalent bond, C R R R each of which (m) may be unsubstituted or substituted with one or more substituents independently chosen from halogen, hydroxyl, nitro, cyano, amino, oxo, —B(OH) L is either (n), (o), or (p) where (n) is a group of the formula where R 17 is hydrogen or C 1 -C 6 alkyl and R 18 and R 18′ are independently chosen from hydrogen, halogen, and methyl; and m is 0, 1, 2, or 3; (o) is a bond; and (p) or a group of the formula B is a monocyclic or bicyclic carbocyclic or carbocyclic-oxy group or a monocyclic, bicyclic, or tricyclic heterocyclic group having 1, 2, 3, or 4 heteroatoms independently selected from N, O, and S and from 4 to 7 ring atoms per ring, or B is a C each of which B is unsubstituted or substituted with one or more substituents independently chosen from (q) and (r) and 0 or 1 substituents chosen from (s) and (t); (q) halogen, hydroxyl, —COOH, cyano, C (r) nitro, C each of which (r) may be unsubstituted or substituted with one or more substituents independently chosen from halogen, hydroxyl, nitro, cyano, amino, oxo, —B(OH) (s) naphthyl, naphthyloxy, indanyl, (4- to 7-membered heterocycloalkyl)C (t) tetrazolyl, (phenyl)C