Patent ID: 9545438
Date: 2017-01-17
CPC Classifications: A61K,A61P,C12N,G01N

Claim:
1. A method of determining an inactivated virus's antigenicity, wherein the inactivated virus is Porcine Reproductive and Respiratory Syndrome (PRRS) virus, the method comprising: purposefully inactivating a PRRS virus with a procedure able to inactivate the virus without affecting the thus inactivated virus's ability to bind and/or to enter and/or to fuse with the host cell; contacting a host cell with the inactivated PRRS virus in vitro; detecting the binding to and/or the internalization into the host cell and/or the fusion of the inactivated virus with the host cell; and determining that the inactivated virus as having has antigenicity if the inactivated virus is able to bind to and/or enter and/or fuse with the host cell.