Patent ID: 9695120
Date: 2017-07-04
CPC Classifications: A61P,C07D

Claim:
1. A compound of formula: and pharmaceutically acceptable salts thereof, wherein R D is C═O; L R is H, linear or branched alkyl, or aryl; Ar Ar two Ar fused to the Ar R R R under the condition that the compound is not (2S)-methyl 1-benzoyl-5-mesitylpyrrolidine-2-carboxylate, (2S)-methyl 1-benzoyl-5-(2,4,6-triethylphenyl)pyrrolidine-2-carboxylate, (2S,5S)-1-benzoyl-5-mesitylpyrrolidine-2-carboxylic acid, (2S)-methyl 1-benzoyl-5-propylpyrrolidine-2-carboxylate, (2S,5S)-methyl 1-benzoyl-5-propylpyrrolidine-2-carboxylate, (2S,5R)-methyl 1-benzoyl-5-propylpyrrolidine-2-carboxylate, (2R,5R)-1-(4-bromothiophene-2-carbonyl)-5-phenylpyrrolidine-2-carboxylic acid, (2R,5S)-1-(3-bromo-2,6-dimethoxybenzoyl)-5-phenylpyrrolidine-2-carboxylic acid, 1-[7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carbonyl]-(5R)-phenyl-pyrrolidine-(2S)-carboxylic acid, and further under the condition that: Ar R