Patent ID: 9636421
Date: 2017-05-02
CPC Classifications: A61K,A61P,C07K

Claim:
1. A process for the preparation of a bioconjugate, the process comprising the step of reacting a reactive group Q 1 of a linker-conjugate with a functional group F 1 of a glycoprotein (B) under condition such that the reactive group Q 1 is reacted with the functional group F 1 of the glycoprotein to covalently link the glycoprotein to the linker-conjugate, wherein the linker-conjugate is a compound comprising a group according to formula (1)  covalently linked to an alpha-end at one side of the formula (1) and an omega-end at the other side of the formula (1), the alpha-end comprising the reactive group Q wherein: the wavy lines indicate covalent linkages to the alpha end and the omega end, a is 0 or 1; and R wherein Q