Patent ID: 9686395
Date: 2017-06-20
CPC Classifications: B01L,G01N,G16H,H04M,Y02A

Claim:
1. A method that enables a point-of-collection, quantitative target measurement of a biomolecular reaction in a collected sample, comprising: providing a modular, diagnostic test platform that includes a sample collection region, a biomolecular reaction region, and a control reaction region; collecting a sample at the sample collection region; providing a smartphone and a smartphone accessory, wherein the smartphone is programmed with a software application that operatively couples the smartphone and the smartphone accessory, further wherein the smartphone accessory is one of operatively connectable to and operatively connected to the smartphone, further wherein the smartphone accessory is adapted to removeably retain the modular, diagnostic test platform including the collected sample, further wherein the smartphone accessory provides an ambient light-free environment for at least the biomolecular reaction region and the control region of the diagnostic test platform including the collected sample at least during a reaction measurement phase of the method, further wherein at least one of the smartphone and the smartphone accessory includes a light source having an emission that can illuminate at least the biomolecular reaction region and the control region of the diagnostic test platform; instructing the software application to activate the light source; making a plurality of ratiometric measurements at different times, with each ratiometric measurement made of a biomolecular reaction in the biomolecular reaction region and a biomolecular reaction in the control reaction region, thereby producing time-charted measurements; and displaying on the smartphone a quantitative target measurement of the biomolecular reaction in the collected sample.