Patent ID: 9554999
Date: 2017-01-31
CPC Classifications: A61K,A61P,C07K,F26B

Claim:
1. A lyophilized synthetic pulmonary surfactant composition comprising: at least one phospholipid and a synthetic polypeptide having at least 10 amino acid residues and represented by a formula: wherein Z represents a hydrophilic amino acid residue and U represents a hydrophobic amino acid residue; wherein each Z is independently R, D, E or K; and each U is independently V, I, L, C, Y, or F; and wherein a is an integer with an average value of about 1 to about 5; b is an integer with an average value of about 3 to about 20; c is an integer of about 1 to about 10; and d is an integer of about 1 to about 3, wherein the lyophilized synthetic pulmonary surfactant composition has a specific surface area at least 2.2 m 2 /g or a porosity above 40% by volume of a total area of the lyophilized synthetic pulmonary surfactant.