Patent ID: 9732055
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07D,Y02A

Claim:
1. A method for treating cancer in a human subject in need thereof comprising administering a composition comprising a therapeutically effective amount of at least one first agent chosen from 2-acetylnaphtho[2,3-b]furan-4,9-dione and pharmaceutically acceptable solvates thereof, wherein said 2-acetylnaphtho[2,3-b]furan-4,9-dione is synthetic and a composition comprising a therapeutically effective amount of at least one second agent chosen from growth factor-targeting agents, kinase-targeting agents, angiogenesis inhibitors, DNA-damaging agents, antimitotic agents, and antimetabolite agents, wherein said cancer is head and neck cancer, brain cancer, breast cancer, lung cancer, liver cancer, pancreatic cancer, ovarian cancer, cervical cancer, uterine cancer, gastrointestinal cancer, kidney cancer, bladder cancer, vulval cancer, cancer of the peritoneum, prostate cancer, thyroid cancer, sarcomas, squamous cell cancer, melanoma, leukemia, lymphoma, or myeloma, wherein said cancer expresses activated STAT3.