Patent ID: 9744348
Date: 2017-08-29
CPC Classifications: A61B,A61N

Claim:
1. An implantable lead comprising: a lead body having a proximal end and a distal end, the lead body comprising an outer layer defining a lumen, the lead body further comprising a first electrical conductor disposed within the lumen of the outer layer, the lead body having a lengthwise axis extending between the proximal end and the distal end; a first electrode coupled to the lead body, the first electrode in electrical communication with the first electrical conductor; a first cellular modulation segment on the external surface of the lead body configured to increase cellular adhesion, the first cellular modulation segment comprising topographic surface features configured to modulate cellular responses, the topographic surface features comprising a plurality of ridges with a pitch between about 20 nm and about 2000 nm, wherein the ridges are oriented perpendicular to the lengthwise axis of the lead body, the first cellular modulation segment disposed within 10 centimeters of the distal end of the lead body; and a second cellular modulation segment on the external surface of the lead body configured to reduce cellular adhesion, the second cellular modulation segment comprising topographic surface features to modulate cellular responses, the topographic surface features comprising a plurality of ridges oriented perpendicular to the lengthwise axis of the lead body, the second cellular modulation segment disposed on a different portion of the lead body than the first cellular modulation segment.