Patent ID: 9629852
Date: 2017-04-25
CPC Classifications: A61K,A61P

Claim:
1. A pharmaceutical composition suitable for ophthalmic use comprising 0.005% w/v latanoprost or a pharmaceutically acceptable salt therof, 0.15% w/v castor oil, 0.2 to 0.75% w/v of polyethylene glycol hydroxystearate, a co-solvent, a chelating agent, a preservative, and pharmaceutically acceptable vehicle, wherein the ratio of oil to polyethylene glycol hydroxystearate is less than 1.0, wherein the composition is in the form of a self-emulsifying micro-emulsion with average droplet size of about 100 nm or less and a zeta potential between −0.1 mV to −20 mV, wherein the composition does not comprise a cationic surfactant, and wherein the composition does not comprise a quaternary ammonium compound.