Patent ID: 9655981
Date: 2017-05-23
CPC Classifications: A61K,A61P

Claim:
1. A method of delivering an imaging agent to a subject, the method comprising the step administering a mixed micelle comprising the imaging agent to the subject, wherein the mixed micelle comprises (a) a poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) (PEO-PHB-PEO) molecule synthesized from poly[(R)-3-hydroxybutyrate] diol with a molecular weight of about 2,300 Da and methoxy-poly(ethylene glycol) monocarboxylic acid having a molecular weight of about 4,900 Da and (b) a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) molecule having a molecular weight of about 12,600 wherein each PEO polymer block has about 100 PEO repeat units and the PPO polymer block has about 65 PPO repeat units, wherein the ratio of PEO-PHB-PEO to PEO-PPO-PEO is between about 7.7:3.3 and 6.3:2.7.