Patent ID: 9630989
Date: 2017-04-25
CPC Classifications: A61K,A61P,C07K

Claim:
1. A method of treating an amyloid-associated disease or disorder in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount a dipeptide analog comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety, with the proviso that either said Trp moiety is not Trp or said beta-sheet breaker moiety is not α-aminoisobutyric acid (Aib) or that said dipeptide analog is not an ester of a Trp-Aib dipeptide, wherein said beta sheet breaker moiety has a chemical structure selected from the group consisting of: and wherein said Trp moiety has a chemical structure selected from the group consisting of: thereby treating the disease or disorder.