Patent ID: 9657349
Date: 2017-05-23
CPC Classifications: A61K,C12N,C12Q,C12Y,G01N

Claim:
1. A method for determining whether a woman has endometrial cancer, comprising the steps of: (a) obtaining an endometrial tissue from a woman suspected of having an increased risk of endometrial cancer; (b) obtaining a normal endometrial tissue; (c) treating said endometrial tissue obtained in step (a) with a lysis buffer to prepare a first lysate; (d) treating said endometrial tissue in obtain step (b) with a lysis buffer to prepare a second lysate; (e) performing a Western blot or an ELISA to quantify PME-1 protein expression level in said first lysate and PME-1 protein expression level in said second lysate; (f) comparing said PME-1 protein expression level in said first lysate with said PME-1 protein expression level in said second lysate; and (g) diagnosing said woman as having endometrial cancer, if there is an increased PME-1 protein expression level in said endometrial tissue obtained in step (a) relative to said normal endometrial tissue obtained in step (b),