Patent ID: 9732112
Date: 2017-08-15
CPC Classifications: C07D,C07H,C12Q

Claim:
1. A method for preparing a 2′,3′-dideoxyadenosine support structure, the method comprising: (a) reacting 2′,3′-dideoxyadenosine with 4,4-dimethoxytriphenylmethyl chloride to obtain a first intermediate; (b) reacting pentane-1,3,5-tricarboxylic acid with oxalyl chloride to obtain a second intermediate; (c) reacting the first intermediate with the second intermediate to obtain a 2′,3′-dideoxyadenosine derivative; and (d) coupling the 2′,3′-dideoxyadenosine derivative to a solid support, thereby obtaining the 2′,3′-dideoxyadenosine support structure.