Patent ID: 9696296
Date: 2017-07-04
CPC Classifications: A61K,G01N

Claim:
1. A method of identifying a composition that can inhibit O-GlcNAcylation of c-Rel, comprising: providing one or more test compositions to be tested; testing the one or more test compositions for their ability to inhibit the attachment of N-acetylglucosamine to serine 350 of c-Rel, wherein testing comprises one or more methods selected from the group consisting of immunocytochemistry, western blot, polymerase chain reaction, mass spectrometry, immunoprecipitation, and gel shift assay; and identifying a test composition that inhibits the attachment of N-acetylglucosamine to serine 350 of c-Rel as an inhibitor of O-GlcNAcylation of c-Rel.