Patent ID: 9701729
Date: 2017-07-11
CPC Classifications: A61K,A61P,C07K

Claim:
1. A peptide having 5 linked epitopes, wherein the 5 epitopes are selected, optionally redundantly, from the group consisting of CTL epitope peptides: the peptide as shown in SEQ ID NO: 1 (PEP1); the peptide as shown in SEQ ID NO: 2 (PEP2); the peptide as shown in SEQ ID NO: 3 (PEP3); the peptide as shown in SEQ ID NO: 4 (PEP4); the peptide as shown in SEQ ID NO: 5 (PEP5); the peptide as shown in SEQ ID NO: 6 (PEP6); and the peptide as shown in SEQ ID NO: 7 (PEP7); linked via linkers, and the peptide having 5 linked epitopes has one or more features selected from the features (1) to (12) below: (1) the peptide comprises a sequence composed of PEP5 and PEP2 successively disposed in such order from the N terminus via a linker; (2) the peptide comprises a sequence composed of PEP2 and PEP4 successively disposed in such order from the N terminus via a linker; (3) the peptide comprises a sequence composed of PEP4 and PEP6 successively disposed in such order from the N terminus via a linker; (4) the peptide comprises a sequence composed of PEP6 and PEP3 successively disposed in such order from the N terminus via a linker; (5) the peptide comprises a sequence composed of PEP4 and PEP1 successively disposed in such order from the N terminus via a linker; (6) the peptide comprises a sequence composed of PEP1 and PEP3 successively disposed in such order from the N terminus via a linker; (7) the peptide comprises a sequence composed of PEP4 and PEP2 successively disposed in such order from the N terminus via a linker; (8) the peptide comprises a sequence composed of PEP1 and PEP4 successively disposed in such order from the N terminus via a linker; (9) the peptide comprises a sequence composed of PEP5 and PEP1 successively disposed in such order from the N terminus via a linker; (10) the peptide comprises a sequence composed of PEP6 and PEP5 successively disposed in such order from the N terminus via a linker; (11) the peptide comprises PEP2 at the C terminus; and (12) the peptide comprises PEP3 at the C terminus.