Patent ID: 9610340
Date: 2017-04-04
CPC Classifications: A61K,A61P

Claim:
1. A multivalent Streptococcus pneumoniae immunogenic composition comprising components including saccharide conjugate components, wherein the saccharide conjugate components consist of conjugates of capsular saccharides of 16 different serotypes of Streptococcus pneumoniae wherein the different Streptococcus pneumoniae serotypes are selected from the group consisting of 1, 2, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F, wherein the capsular saccharides are separately conjugated to 2 or more different carrier proteins, wherein the serotype 22F capsular saccharide has an average saccharide size of between 50 and 800 kDa, wherein the serotype 19F capsular saccharide is conjugated to diphtheria toxoid, wherein the serotype 19F capsular saccharide is the only capsular saccharide conjugated to the diphtheria toxoid, wherein the capsular saccharides from half of the 16 different