Patent ID: 9708274
Date: 2017-07-18
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound of formula I: wherein Ar is selected from a group consisting of: wherein X is N; R R wherein R wherein R R or R R 8 and R 9 are independently of each other selected from the group consisting of: H and C 1-3 -alkyl optionally substituted with 1-3 F or one OH or NH 2 ; R 1 is selected from a group consisting of: wherein R R or wherein R and wherein R —NH—C(═O)—N(C —N(C R 2 is selected from a group consisting of halogen, CN, OH, NH 2 , C 1-3 -alkyl, C 2-3 -alkenyl, C 2-3 -alkynyl, C 3-5 -cycloalkyl, —O-cyclopropyl and —S—C 1-3 -alkyl, wherein each alkyl group is optionally substituted with one or more F; and wherein, if not otherwise specified, each alkyl group in the above definitions is linear or branched and may be substituted with one to three F; or a stereoisomer or salt thereof.