Patent ID: 9574196
Date: 2017-02-21
CPC Classifications: A61K,A61P,C12N,Y02A

Claim:
1. A eubacterial minicell derived from a minicell-producing bacteria, wherein the minicell-producing bacteria comprises: an expressible cell division gene, wherein the cell division gene is selected from the group consisting of zipA, sulA, secA, dicA, dicB, dicC, dicF, ftsA, ftsI, ftsN, ftsK, ftsL, ftsQ, ftsW, ftsZ, minC, minD, minE, seqA, ccdB, sfiC, and ddlB; and an expressible gene encoding a homing endonuclease, wherein the homing endonuclease gene is a transgene, and wherein the chromosome of the minicell-producing bacteria comprises one or more recognition sites of the homing endonuclease.