Patent ID: 9562096
Date: 2017-02-07
CPC Classifications: A61K,A61P,C07K

Claim:
1. An antibody or antigen binding fragment thereof comprising any one of the following combinations of a heavy chain and a light chain: a) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 58 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 64 (H-1140), said heavy chain optionally lacking one to five carboxyl-terminal amino acids, b) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 58 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 66 (H-1143), said heavy chain optionally lacking one to five carboxyl-terminal amino acids, c) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 62 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 66 (H-2143), said heavy chain optionally lacking one to five carboxyl-terminal amino acids, d) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 62 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 64 (H-2140), said heavy chain optionally lacking one to five carboxyl-terminal amino acids, e) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 56 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 64 (H-1040), said heavy chain optionally lacking one to five carboxyl-terminal amino acids, or f) a heavy chain comprising amino acid Nos. 20 to 463 of SEQ ID NO: 60 and a light chain comprising amino acid Nos. 21 to 239 of SEQ ID NO: 64 (H-2040), said heavy chain optionally lacking one to five carboxyl-terminal amino acids.