Patent ID: 9592474
Date: 2017-03-14
CPC Classifications: B01D,C07K

Claim:
1. A virus removal methodology comprising the steps of: a. providing a filtration device comprising a housing having a fluid inlet and a filtrate outlet, and containing at least one two-layered cocast membrane having one asymmetric ultrafiltration layer and one microporous asymmetric layer, wherein the membrane is produced from two polymer solutions, wherein: b. providing a manufactured protein-containing solution comprising a predominant solute, wherein the predominant solute in the solution is said protein, and wherein the solution is prone to contamination by said virus; and c. flowing the solution through the filtration device under conditions sufficient to effect substantial passage of the protein through each layer of the membrane and out of the housing through the filtrate outlet, whereby any virus contaminating the manufactured protein-containing solution is substantially prevented from passage through the membrane, and is substantially removed from the solution.