Patent ID: 9738887
Date: 2017-08-22
CPC Classifications: B01L,B29C,B29L,C12M,C12N,C12Q

Claim:
1. A cartridge, configured to facilitate processing and detecting of a nucleic acid, comprising: a first layer, defining a sample port, a reagent port, a fluid port, and a detection chamber; an elastomeric layer; an intermediate substrate coupled to the first layer, such that the elastomeric layer is situated between the intermediate substrate and the first layer, wherein the intermediate substrate defines a chamber with a corrugated surface directly opposing the first layer, wherein the corrugated surface defines a set of voids external to the chamber and accessible from a direction perpendicular to a broad surface of the first layer, and wherein at least a portion of the corrugated surface includes a set of openings that provide access to the elastomeric layer; and a fluidic pathway, wherein the fluidic pathway is fluidically coupled to the sample port, the reagent port, the fluid port, and the detection chamber.