Patent ID: 9586999
Date: 2017-03-07
CPC Classifications: A61P,C07K

Claim:
1. A method of treating pain or epileptic seizures comprising administering to a subject in need thereof an effective amount of a neuropeptide modified to have an increased permeability of the blood brain barrier, wherein the modified neuropeptide is derived from an unmodified neuropeptide selected from galanin, somatostatin, delta-sleep inducing peptide, and neuropeptide Y, wherein the modified neuropeptide comprises: a first modification relative to the unmodified peptide that increases the lipophilic character of the modified neuropeptide selected from at least one of: a second modification relative to the unmodified neuropeptide that increases the basicity of the modified neuropeptide when compared to the unmodified neuropeptide, with the second modification being selected from at least one of: