Patent ID: 9566339
Date: 2017-02-14
CPC Classifications: A61K,A61P

Claim:
1. A drug delivery system comprising: a biologically active antibiotic chemically bonded to a biologically active substrate with a chemical bond, the substrate adapted for insertion into a patient during a medical procedure, wherein the substrate comprises tricalcium phosphate and at least one of magnesium aluminate and calcium aluminate, and wherein the antibiotic is one of a tetracycline and a ciprofloxacin; wherein the substrate is insoluble in a normal physiological environment where no infection or inflammatory response is present and wherein the antibiotic remains inactive for pharmaceutical purposes as long as the substrate is insoluble; wherein at least a portion of the substrate becomes soluble and dissolves releasing the antibiotic from the substrate by breakage of the chemical bond upon the occurrence of a local infection near the substrate.