Patent ID: 9616153
Date: 2017-04-11
CPC Classifications: A61F,A61L

Claim:
1. A bone graft substitute comprising: a porous matrix; a reinforcing outer layer covering at least a portion of the porous matrix and having at least one opening providing access to the porous matrix, the reinforcing outer layer having an inside surface; and a plurality of reinforcement ribs disposed along the inside surface of the reinforcing outer layer along the entire length of the bone graft substitute, each reinforcement rib of the plurality of reinforcement ribs being surrounded by and contacting the porous matrix on at least three sides and the inside surface of the reinforcing outer layer, and each reinforcement rib of the plurality of reinforcement ribs comprising four side walls, the four side walls defining a hollow region that runs the entire length of the reinforcement rib, the four side walls comprising holes to further expose the hollow region, wherein the plurality of reinforcement ribs comprise a biodegradable material and are integrally formed with the outer layer, and the porous matrix comprises a bioactive agent comprising BMP-2 at a concentration from about 1.0 to 4.0 mg/ml, and the at least one opening is disposed between the plurality of reinforcement ribs.