Patent ID: 9539242
Date: 2017-01-10
CPC Classifications: A61K,A61P,C12Q,G16B

Claim:
1. A method of treating an alcohol-related disease or disorder, comprising: administering to a patient in need thereof a therapeutically effective amount of ondansetron, wherein the disease or disorder is selected from: alcohol abuse, heavy drinking, excessive drinking, and alcohol dependence and the patient's HTR3B gene and optionally serotonin transporter gene SLC6A4 and/or HTR3A gene is known to have a genotype selected from sets (a.)-(d.): (a.) the AC genotype of rs17614942; (b.) the AC genotype of rs17614942, the LL genotype of 5-HTTLPR, and the TT genotype of rs1042173; (c.) the AC genotype of rs17614942 and the LL genotype of 5-HTTLPR; (d.) the AC genotype of rs17614942 and at least one genotype selected from: