Patent ID: 9730902
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07C,C07D

Claim:
1. A method for treating a disorder in a subject characterized by high polyamine content in tissues, the method comprising administering to a subject a pharmaceutical composition comprising compound 3d, 3e, 3f, 4a, 4b, 4c, 4d, 5a, 5b, 5c, 5d, 5e, 5f, 6a, 6b, 6c, 6d, 7a, 7b, 7c, 7d, 8a, 8b, 8c, 8d, 8e, 8f, 9a, 9b, 9c, 9d, 10a, 10b, 10c or 10d, or a pharmaceutically acceptable salt thereof in an amount effective to inhibit polyamine transporter activity in cells of the subject, wherein the disorder is colon cancer or pancreatic cancer.