Patent ID: 9586911
Date: 2017-03-07
CPC Classifications: A61K,C07D

Claim:
1. A method of promoting hydration of mucosal surfaces, promoting ocular or corneal hydration, or improving mucociliary clearance in a human in need thereof, comprising administering to the human an effective amount of a compound of formula (I): wherein Ar is a moiety selected from the group of: X is selected from —CH n is an integer selected from 0, 1, 2, 3, 4, 5, and 6; R is a polyhydroxylated alkyl group having from 3 to 8 carbon atoms; R q is an integer selected independently in each instance from 1, 2, 3, 4, 5, and 6; and Y is a phenyl, naphthyl, or pyridyl ring, with each phenyl, naphthyl, or pyridyl ring substituted by 0, 1, 2, or 3 substituents independently selected from halogen, —OH, —CN, —NO or a pharmaceutically acceptable salt thereof.