Patent ID: 9616096
Date: 2017-04-11
CPC Classifications: A61K,A61P

Claim:
1. A method of treating hypertension in a subject comprising administering to that subject a therapeutically effective amount of a stable oral liquid formulation, comprising: (i) about 1 mg/ml lisinopril or a pharmaceutically acceptable salt or solvate thereof; (ii) about 150 mg/ml of a sweetener that is xylitol; (iii) a buffer comprising about 0.86 mg/ml citric acid and about 1.44 mg/ml sodium citrate; (iv) about 0.8 mg/ml of a preservative that is sodium benzoate; and (v) water; wherein the pH of the formulation is between about 4 and about 5; and wherein the formulation is stable at about 25±5° C. for at least 12 months.