Patent ID: 9732094
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07C,C07D

Claim:
1. Process for the preparation of a compound of formula (I) in which X is CH, CF, S or N, Y is CH, S or N, Z is C or N, ---- forms, if Z═C, a double bond together with the single bond, n is 1 or 2, where m is 1 or 2, where R R Cyc is phenyl, which may be unsubstituted or mono- or disubstituted, independently of one another, by R Het R LA is unbranched or branched alkyl having 1-5 C atoms, which may be saturated or partially unsaturated, in which 1-3 H atoms may be replaced by Hal, or one H atom may be replaced by CN or Het Het Hal is F, Cl, Br or I; or a physiologically acceptable salt, tautomer or stereoisomer thereof, including mixtures thereof in all ratios, comprising the following steps: (a) reacting a compound of formula (V) in which LG is a conventional leaving group with a compound of formula (IV) in which A is boronic acid or a boronic acid ester, giving the compound of formula (I), and optionally (b) converting a base or acid of the compounds of formula (I) into one of its salts.