Patent ID: 9708352
Date: 2017-07-18
CPC Classifications: C07B,C07F

Claim:
1. A process for preparation of Echothiophate Iodide (I), comprising the steps of: a) providing a solution of 2-(dimethylamino) ethane thiol or its salt and a base in an organic solvent; b) optionally heating the reaction mixture to 50-70° C. and obtaining a residual mass; c) treating the step a) or b) material with diethyl halogen phosphate in an organic solvent having boiling point greater than 100° C. to obtain S-2-(dimethyl amino) ethyl O,O-diethyl phosphorothioate of Formula (II); d) reacting S-2-(dimethyl amino)ethyl O,O-diethyl phosphoro thioate (II) of step c) with methyl iodide in an organic solvent; and e) isolating pure Echothiophate Iodide (I).