Patent ID: 9745229
Date: 2017-08-29
CPC Classifications: B01J,C07B,C07C,C07D,C07F

Claim:
1. A method for producing an optically active amine, comprising the step of: reducing an imino group of an imine compound or reducing an unsaturated bond of a heterocyclic compound in the presence of at least one complex selected from the group consisting of a ruthenium complex of the following formula (1), a ruthenium complex of the following formula (2), and an iridium or rhodium complex of the following formula (4) and of hydrogen gas serving as a hydrogen donor: wherein * indicates an asymmetric carbon atom, R R Y represents a hydrogen atom or a deuterium atom,  is p-cymene, benzene, mesitylene or hexamethylbenzene, and Q wherein * indicates an asymmetric carbon atom, R  is as defined above, A represents a trifluoromethanesulfonyloxy group, a p-toluenesulfonyloxy group, a methanesulfonyloxy group, a benzenesulfonyloxy group, a hydrogen atom, a deuterium atom, or a halogen atom, and j and k each represent 0 or 1, provided that j+k is not 1; and wherein * indicates an asymmetric carbon atom, M represents iridium or rhodium, L represents a cyclopentadienyl or pentamethylcyclopentadienyl ligand, and R