Patent ID: 9682160
Date: 2017-06-20
CPC Classifications: A01N,A61K,A61L,A61P

Claim:
1. A method of sterilizing a fetal support tissue product, comprising: (a) contacting the fetal support tissue product with an isotonic solution comprising about 10% glycerol, or about 20% to about 70% glycerol, wherein the fetal support tissue product is from placental amniotic membrane, umbilical cord amniotic membrane, chorion, amnion-chorion, placenta, umbilical cord, or any combination thereof; and (b) exposing the fetal support tissue product at a temperature of at or below about 0° C. to an effective dosage of γ-irradiation for an effective duration of time to sterilize the fetal support tissue product and produce a sterilized fetal support tissue product in which HC-HA/PTX3 complex-mediated biological activity of the fetal support tissue product is substantially maintained.