Patent ID: 9701758
Date: 2017-07-11
CPC Classifications: C07K,C12N,G01N

Claim:
1. An isolated antibody or antibody fragment thereof, that specifically binds to a CD19-specific scFv (FMC63) chimeric antigen receptor (CAR) polypeptide, wherein the isolated antibody or antibody fragment comprises a set of complementarity determining regions (CDRs) HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3, wherein (a) HCDR1 has the amino acid sequence of SEQ ID NO: 2; (b) HCDR2 has the amino acid sequence of SEQ ID NO: 3; (c) HCDR3 has the amino acid sequence of SEQ ID NO: 4; (d) LCDR1 has the amino acid sequence of SEQ ID NO: 6; (e) LCDR2 has the amino acid sequence of SEQ ID NO: 7; and (f) LCDR3 has the amino acid sequence of SEQ ID NO: 8.