Patent ID: 9547003
Date: 2017-01-17
CPC Classifications: C07K,G01N

Claim:
1. A peptide tag and binding partner pair wherein a) said peptide tag is a peptide fragment of an isopeptide protein, said tag having a length of at least 5 amino acids but no more than 50 amino acids, and comprises a first reactive residue involved in formation of an intramolecular isopeptide bond in an isopeptide protein, wherein said peptide tag is either unconjugated or is conjugated to a heterologous protein or peptide or to another molecule and wherein said isopeptide protein is selected from the group consisting of b) said binding partner (i) comprises a different fragment of an isopeptide protein as set forth in (a)(i) or (a)(ii) wherein said fragment is at least 20 amino acids in length and (ii) comprises a second reactive residue involved in the isopeptide bond in said isopeptide protein, wherein the binding partner does not include the first reactive residue of the peptide tag; and c) said peptide tag and binding partner are capable of binding to each other and forming an isopeptide bond between the first and second reactive residues.