Patent ID: 9603852
Date: 2017-03-28
CPC Classifications: A61K,A61P

Claim:
1. A method of treating a condition selected from the group consisting of obesity and pulmonary arterial hypertension comprising administering to a subject having obesity and/or pulmonary arterial hypertension a compound of formula (I) in an amount effective to treat obesity and/or pulmonary arterial hypertension, wherein if the subject has obesity, the compound is administered in an amount effective to reduce glucose intolerance, wherein if the subject has pulmonary arterial hypertension, the compound is administered in an amount effective to reduce right ventricular pulse pressure, and wherein formula (I) is: wherein W is O or NR5; R1 is H, —CH R2 is R3 is —(CH R4 and R5 are independently H or —CH R6 is O or NR9; R7 is H, —CH R8 is H, —OH, —CH R9 is H or —CH R10 is —CH R11 is —SO and R12 is —CH where X1, X2, X3, X4, X5, X6 and X7 are independently H, halogen, —OH, —CH where a=0-2; b=1-6; c=0-1; d=4-7; and e=0-1; or a pharmaceutically acceptable salt thereof.