Patent ID: 9671409
Date: 2017-06-06
CPC Classifications: B05D,C23C,G01N,H01J,Y10T

Claim:
1. A method of forming a calcinated silicate film for laser desorption ionization mass spectrometry, the method comprising: fabricating a layer of gold onto a substrate; alternately depositing layers of poly(allylamine hydrochloride) (PAH) and a sodium silicate solution onto a surface of the layer of gold; calcinating the alternately deposited layers of PAH and sodium silicate solution to form a calcinated nanofilm, the calcinated nanofilm having a thickness of 2 to 50 nanometers with a porosity of at least one nanometer; introducing a tailoring surface property to the calcinated nanofilm; and performing matrix-free laser desorption ionization mass spectrometry (LDI-MS) and/or surface-assisted laser desorption ionization (SALDI-MS) analysis of biomolecules on the calcinated nanofilm.