Patent ID: 9556167
Date: 2017-01-31
CPC Classifications: A61K,A61P,B82Y,C07D,C07K

Claim:
1. A compound according to the chemical structure: Wherein [ABT] is an antibody binding moiety comprising a hapten which is capable of binding to an antibody in a patient according to the chemical formula: Where Y′ is H or NO X is O, CH R X′ is CH R Z is a bond, a monosaccharide, disaccharide, oligosaccharide, glycoprotein or glycolipid; X X″ is O, CH X X R wherein each of said DNP groups is a dinitrophenyl group linked through an amino group or a thio group as indicated to the amino acid moiety; [CBT] is a cell binding moiety capable of binding to prostate specific membrane antigen (PSMA) on the cell surface of a cancer cell in said patient according to the chemical formula: Where X X R k is an integer from 0 to 20; [TLR] is a Toll-like Receptor (TLR) agonist moiety according to the chemical structure; Where R and X [TLR] is a group according to the chemical structure: where X or a salt form thereof; L L L Wherein any one or more of L [MULTICON] is a multifunctional connector molecule which binds to said L Wherein each Y Each X″ is N—H; Each n, n′ and n″ in a molecule is independently an integer from 1 to 15, and Each of NL1, NL2 and NL3 is independently an integer from 1 to 10 wherein n≧NL1, n′≧NL2 and n″≧NL3, or a pharmaceutically acceptable salt, stereoisomer, diastereomer, enantiomer, solvate or polymorph thereof.