Patent ID: 9732138
Date: 2017-08-15
CPC Classifications: C07K,C12Q,G01N,Y10T

Claim:
1. A method of detecting a mutation in a KCNJ10 nucleic acid in a bodily sample from a subject, said method comprising: performing an allele specific detection assay on a KCNJ10 nucleic acid in said bodily sample obtained from said subject, wherein said allele specific detection assay comprises contacting the KCNJ10 nucleic acid with a detectably labeled oligonucleotide under high stringency hybridization conditions, wherein the detectably labeled oligonucleotide is substantially complementary to a KCNJ10 nucleic acid sequence comprising a KCNJ10 mutation, and wherein the KCNJ10 nucleic acid sequence comprises a sequence selected from the group consisting of SEQ ID NOs: 3-8, and detecting whether hybridization of said oligonucleotide with said KCNJ10 nucleic acid in said bodily sample takes place, whereby, if hybridization of said oligonucleotide with said KCNJ10 nucleic acid in said bodily sample is detected, a mutation in said KCNJ10 nucleic acid in said bodily sample from said subject is detected.