Patent ID: 9678038
Date: 2017-06-13
CPC Classifications: B01J,B01L,B81B,B81C,B82Y,C12Q,G01N,Y10S

Claim:
1. A method of analyzing at least one macromolecule, comprising the steps of: transporting at least one macromolecule in a fluid sample into a nanochannel, such that the at least one macromolecule is in an elongated state within the nanochannel; maintaining the at least one macromolecule in an elongated state within the nanochannel without application of a shear force; detecting at least one signal transmitted from the at least one elongated macromolecule within the nanochannel; and correlating the detected signal to at least one property of the at least one macromolecule; wherein the macromolecule is DNA and the detected signals are correlated to the base pair sequence of said DNA; and wherein the nanochannel is surmounted by sealing material to render the nanochannel at least substantially enclosed.