Patent ID: 9607818
Date: 2017-03-28
CPC Classifications: H01J

Claim:
1. A multimode ionization device adapted for a mass spectrometer which includes a receiving unit disposed to admit therein ionized analytes that are derived from a sample, and that are to be analyzed by the mass spectrometer, said multimode ionization device comprising: an electrospray unit including a reservoir for providing a liquid electrospray medium, and a nozzle which is disposed downstream of said reservoir and which is configured to form an electrospray plume of the liquid electrospray medium thereat, said nozzle being disposed to be spaced apart from the receiving unit so as to define a traveling path therebetween; a charge generating unit configured to laden the liquid electrospray medium with a plurality of charges when the liquid electrospray medium runs up to said nozzle, thereby permitting the liquid electrospray medium to leave said nozzle as the electrospray plume for heading toward the receiving unit to be admitted thereinto; and a plasma supplying unit configured to generate and guide a plasma plume to mix with the electrospray plume so as to form a plume combination in a confluent zone which is upstream of a linearly-extending end zone of the traveling path, and which is oriented to permit at least one of analytes carried in the plume combination to travel to the receiving unit along the linearly-extending end zone, such that as a result of approaching the receiving unit along the linearly-extending end zone, charges of the plume combination will pass on to said at least one of the analytes carried in the plume combination to thereby form a corresponding one of the ionized analytes, wherein said charge generating unit includes