Patent ID: 9737229
Date: 2017-08-22
CPC Classifications: A61B

Claim:
1. A method to noninvasively estimate cardiac chamber size and cardiac mechanical function, including left ventricular ejection fraction, the method comprising: obtaining, by a processor, three-dimensional (3D) orthogonal data from a measurement of one more surface electrical signals of a subject, wherein the three-dimensional (3D) orthogonal data is derived from measurements acquired via noninvasive equipment configured to measure electrical properties of the heart; determining, by the processor, via a numerical integral operation of one or more vectorcardiogram components associated with a vectorcardiogram of the 3D orthogonal data, i) one or more first parameters selected from the group consisting of a sum QRST integral parameter, a 3D volume integral parameter, a spatial QRST angle parameter, a 3D QRS loop volume parameter, a 3D T-loop volume parameter, a spatial ventricular gradient parameter, a spatial ventricular gradient azimuth parameter, a spatial ventricular gradient elevation parameter, and ii) one or more second parameters associated with beat-to-beat variability of the one or more first parameters; and determining, by the processor, an estimate cardiac chamber size parameter by applying the one or more first parameters and the one or more second parameters in one or more first models associated with the cardiac chamber size; and determining, by the processor, one or more cardiac chamber mechanical function parameters by applying the one or more first parameters and the one or more second parameters in one or more second models associated with each cardiac chamber mechanical functions; and cause, by the processor, the estimate cardiac chamber size parameter and the one or more cardiac chamber mechanical function parameters to be presented in a graphical user interface.