Patent ID: 9624540
Date: 2017-04-18
CPC Classifications: C12Q,G01N,G02B

Claim:
1. An analytical device comprising: a substrate; an integrated illumination element comprising a waveguide source; a plurality of illumination volumes; and a plurality of detector elements; wherein the integrated illumination element is disposed above the surface of the substrate; the plurality of detector elements are disposed below the surface of the substrate; the integrated illumination element is partly surrounded by an opaque layer; and the plurality of illumination volumes are contained in a plurality of nanowells disposed above the surface of the substrate and in the same layer of the device as the integrated illumination element, wherein the nanowells are configured in a row adjacent to the integrated illumination element, wherein at least a first nanowell comprises a bottom surface and a first side surface, and wherein the first nanowell is optically coupled to the integrated illumination element through an opening in the opaque layer and to one of the detector elements.