Patent ID: 9554991
Date: 2017-01-31
CPC Classifications: A61K,A61P

Claim:
1. A gastro-retentive agent delivery device for oral intake, the device configured for unfolding from a folded configuration for oral intake to an unfolded configuration for gastric retention, the device comprising: a first outer membrane and a second outer membrane sandwiching an internal layer therebetween; the internal layer being different from said first outer membrane and from said second outer membrane; the internal layer comprising a first active agent distributed therein; the internal layer being configured for imparting mechanical strength to the device sufficient to enable, upon unfolding of the device, the preservation of said unfolded configuration to provide gastric retention; at least one first immediate release layer, overlying said first outer membrane, said at least one first immediate release layer being different from said outer membrane and from said internal layer, said at least one first immediate release layer comprising a respective second active agent, the at least one first immediate release layer configured for providing immediate release of the respective second active agent in the stomach; wherein said first active agent and said respective second active agent are the same or different; wherein in the folded configuration the device is sufficiently compact to be placed within a capsule dissolvable within the stomach.