Patent ID: 9669134
Date: 2017-06-06
CPC Classifications: A61L

Claim:
1. A method of treating a mammal that has suffered a myocardial infarction to stimulate repair or survival of cardiac muscle, and to stimulate left ventricular remodeling, the method comprising a step of administering IGF-1 to the individual by intracoronary delivery upstream of the myocardial infarction in sufficient quantity to reduce the effects of the myocardial infarction on the individual by exerting anti-apoptotic and/or cardiotrophic effects on affected or diseased tissue, in which the IGF-1 is administered to the individual by means of a stent that comprises the IGF-1 and which is introduced into the coronary circulation upstream of the site of the myocardial infarction, wherein the stent is adapted for delivery of IGF-1 into the coronary circulation over an elution period of between 1 hour and 14 days.