Patent ID: 9555029
Date: 2017-01-31
CPC Classifications: A61K

Claim:
1. A method of treating a patient for an inflammatory disorder, wherein the inflammatory disorder is chronic gout, familial Mediterranean fever or Behcet's disease, with colchicine while concomitantly administering a second drug that is not an inhibitor of the cytochrome P450 3A4 isoenzyme (CYP3A4) but is an inhibitor of P-glycoprotein 1 (P-gp), wherein the second drug is propafenone, wherein the method comprises: a) administering to the patient a therapeutically effective fixed maintenance dose of colchicine in an amount of from about 0.6 to about 1.2 mg/day, for a maintenance period of a plurality of days, without administering propafenone; b) after step (a), administering to the patient one or more therapeutically effective doses of propafenone; and c) concomitantly with step (b), administering to the patient the fixed maintenance dose of colchicine of step (a) without dose reduction.