Patent ID: 9724421
Date: 2017-08-08
CPC Classifications: A61K,A61P

Claim:
1. A chemoembolization composition for anti-angiogenic agent delivery comprising an anti-angiogenic agent and a sugar or poly-ol loaded in anionic drug eluting beads, wherein said anti-angiogenic agent is selected from the group consisting of sunitinib, angiostatin K1-3, arresten, DL-α-difluoromethyl-ornithine, fumagillin, genistein, staurosporine, (±)-thalidomide, tumstatin, axitinib, bortezomib, bosutinib gefitinib, pazopanib, semaxanib, sorafenib, vandetanib, vatalanib, canertinib, dovitinib, dasatinib, erlotinib, imatinib, lapatinib, masutinib, mubitinib, lestaurtinib, pazopanib, tandutinib and vismodegib, and wherein said anionic drug eluting beads are selected from the group consisting of sulphonate-modified polyvinyl alcohol hydrogel beads and carboxyl-modified polyvinyl alcohol-co-sodium acrylate beads.