Patent ID: 9663817
Date: 2017-05-30
CPC Classifications: C12Q,G01N

Claim:
1. A method comprising the steps of: (a) providing a reference mass spectrum of an antimicrobial compound, its enzymatic modification product, its molecular target, or of a substrate compound of a modifying enzyme; (b) exposing a microorganism, a cell lysate thereof, or a growth medium supernatant thereof, to said antimicrobial compound or said substrate compound in aqueous liquid on a mass spectrometric sample support to thereby provide an exposed sample; (c) acquiring a mass spectrum of the exposed sample; (d) comparing the mass spectrum acquired in step c) with the reference mass spectrum of step a), and (e) determining from said comparison whether modification of said antimicrobial compound, its modification product or its molecular target or of said substrate compound has occurred following said exposure.