Patent ID: 9662327
Date: 2017-05-30
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound having Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein: X is CR Y is —N(R Z is —O—, —S—, —C(R) W is C(R V is N or C(R); each R is independently selected from hydrogen, methyl or CF each R or two R R each R R R any alkylene moiety present in R any terminal methyl moiety present in R each R Q is selected from aryl, heteroaryl, carbocyclyl and heterocyclyl; and Q is optionally substituted with up to 3 substituents independently selected from C each R G is a bond or a bivalent C L is a covalent bond or a bivalent C M is E, or a 3-10 membered monocyclic or bicyclic, saturated, partially unsaturated, or aromatic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, and wherein said ring is substituted with at 1-4 groups independently selected from -D-E, oxo, NO D is a covalent bond or a bivalent C E is hydrogen, C each R m is 0, 1, 2 or 3; provided that: when X is —C(CN)—, Y is —N(R when X is —C(CN)—, Y is —N(R