Patent ID: 9579621
Date: 2017-02-28
CPC Classifications: B01J,G01N,G02B

Claim:
1. A method for preparing a device for detecting one or more label-free analytes and detecting the one or more label-free analytes, the method comprising: generating electromagnetic radiation from a broadband source; coupling the electromagnetic radiation generated by the broadband source to the device for detecting one or more label-free analytes, wherein the device comprises: coating the one or more target binding molecules onto the array of photonic crystal microcavities; measuring a first transmission spectrum, wherein measuring the first transmission spectrum comprises measuring the electromagnetic radiation from the output ridge waveguide of the device; identifying a first minimum of the first transmission spectrum; exposing the device to the one or more label-free analytes to allow the selective binding of the one or more label-free analytes to the one or more target binding molecules coated on the array of photonic crystal microcavities; measuring a second transmission spectrum, wherein measuring the second transmission spectrum comprises measuring the electromagnetic radiation from the output ridge waveguide of the device; identifying a second minimum of the second transmission spectrum; comparing the second minimum of the second transmission spectrum with the first minimum of the first transmission spectrum; and identifying the one or more label-free analytes from the comparison between the second minimum of the second transmission spectrum with the first minimum of the first transmission spectrum.