Patent ID: 9683208
Date: 2017-06-20
CPC Classifications: C12M

Claim:
1. A horizontal fermentor for production of microbes comprising: a horizontal disposed cylindrical vessel wherein: said vessel is oriented so that the axis of the cylinder is horizontal; said fermentor comprising includes: a second head affixed to a second end of the cylinder, the second head operable to open allowing access to the interior of the cylinder and operable to close thereby sealing the second end of the cylinder; and a sparge plate operable for aeration and pressurization wherein the combination of aeration, pressurization, and agitation will support microbial growth and metabolism at small scale and large scale with oxygen mass transfer rates at or above 150 mMoleOxygen/Liter/Hr when operating with sparge gas consisting of air only; and a containment bag, operable to contain material for one or more of microbial growth culturing microorganisms and recombinant protein production; and a heat transfer jacket operable for heating/cooling wherein the cylinder and first head further comprise an external heat transfer fluid cavity; and a heat transfer jacket operable for heating/cooling wherein the removable second head further comprise an external heat transfer fluid cavity.