Patent ID: 9725753
Date: 2017-08-08
CPC Classifications: C12Q,G01N

Claim:
1. A biomolecule information analysis apparatus, comprising: a first electrode and a second electrode forming a molecule path configured to permit a biomolecule to pass therethrough; an electric voltage application circuit coupled to the first electrode and configured to apply an electric voltage to the first and the second electrodes; an integration circuit coupled to the second electrode and configured to accumulate and integrate electrical charges corresponding to an electric current caused to flow from the second electrode by application of the electric voltage from the electric voltage application circuit to the first and the second electrodes and the passing of the biomolecule through the molecule path to produce an integrated electric current value, which varies based on a type of a base of DNA of the biomolecule, and which converges to a single accumulated charge value as integration time increases; an amplifier coupled to the integration circuit and configured to receive and amplify the integrated electric current value and to output an amplified result; and a comparison circuit coupled to the amplifier and the comparison circuit comprising a signal processor that is programmed to control the operation of the integration circuit and the amplifier and to control the integration of the electrical charges corresponding to the electric current caused to flow from the second electrode by application of the electric voltage from the electric voltage application circuit to the first and the second electrodes and the passing of the biomolecule through the molecule path to produce the integrated electric current value, which converges to a single accumulated charge value as integration time increases, and to identify a structure of the biomolecule by comparing the amplified result with at least one predetermined reference value.