Patent ID: 9663830
Date: 2017-05-30
CPC Classifications: C12Q

Claim:
1. A method for diagnosing sepsis comprising: (a) contacting a plurality of γPNA capture probes to genomic material in a clinical sample obtained from a subject suspected of having sepsis, wherein the γPNA capture probes comprise at least one sequence from one or more of the groups of probes selected from the group consisting of: SEQ ID NOS: 1-18, SEQ ID NOS: 19-22, SEQ ID NOS: 23-28, SEQ ID NOS: 29-34, SEQ ID NOS: 35-38, SEQ ID NOS: 39-57, SEQ ID NOS: 58-72, SEQ ID NOS: 73-91, SEQ ID NOS: 92-94, SEQ ID NOS: 95-97, SEQ ID NOS: 98-110, SEQ ID NOS: 111-113, SEQ ID NOS: 114-117, SEQ ID NOS: 118-119, SEQ ID NOS: 120-121, SEQ ID NOS: 122-153, SEQ ID NOS: 154-166, SEQ ID NOS: 167-190, SEQ ID NOS: 191-193, SEQ ID NOS: 194-196, SEQ ID NOS: 197-211, SEQ ID NOS: 212-215, SEQ ID NOS: 216-230, complementary sequence thereof, and functional equivalents thereof; (b) heating the γPNA capture probes and the clinical sample; (c) invading a plurality of targeted sepsis-related genomic material by the γPNA capture probes; and (d) detecting a presence of one or more targeted genomic material, wherein detection of the presence of targeted genomic material is indicative of a sepsis infection.