Patent ID: 9562046
Date: 2017-02-07
CPC Classifications: A61K,A61P,C07D

Claim:
1. Cytotoxic compound of formula I, wherein R is H, methyl or methylene substituted by C 1 -C 4 straight or branched alkyl, R 1 is selected from the group consisting of H, C 1 -C 4 straight or branched alkyl, methoxy, methoxy substituted by from one to three fluorine, and halogen; R 2 is H or C 1 -C 4 straight or branched alkyl; X is CH or N; and Y is CH or N; provided that R is methylene substituted by C 1 -C 4 straight or branched alkyl if R 1 is H, halogen, or C 1 -C 4 alkyl, R 2 is H or C 1 -C 4 straight or branched alkyl, X is N and Y is N, or a pharmaceutically acceptable salt of the compound of formula I, or a pharmaceutically acceptable metal complex of the compound of formula I with a metal other than Fe 2+ , Fe 3+ , or Co 2+ .