Patent ID: 9682061
Date: 2017-06-20
CPC Classifications: A61K,A61P

Claim:
1. A method of treating a bacterial infection in a human subject, comprising administering a therapeutically effective amount of a glycopeptide antibiotic to the human subject having the bacterial infection, wherein the glycopeptide antibiotic is oritavancin, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, or a mixture thereof, wherein the effective amount of the glycopeptide antibiotic is between about 15 and 50 mg/kg body weight, wherein the effective amount of the glycopeptide antibiotic provides a fraction of glycopeptide antibiotic bound to serum proteins in the subject in the range of about 50% to about 95%, and wherein the fraction of glycopeptide antibiotic bound to serum proteins is determined from serum obtained from the subject.