Patent ID: 9550991
Date: 2017-01-24
CPC Classifications: A61K,A61P,C12N,Y02A

Claim:
1. An antibacterial complex comprising: i) a decoy nucleic acid sequence comprising a sequence comprising or encoding a binding site for bacterial sigN alternative sigma54 factor, wherein the sequence comprising or encoding the binding site for bacterial sigN alternative sigma54 factor is selected from the group consisting of SEQ ID NO:2, SEQ ID NO:8, SEQ ID NO:14, SEQ ID NO:20, SEQ ID NOS:3 and 4, SEQ ID NOS:9 and 10, SEQ ID NOS:15 and 16, SEQ ID NO:21, and SEQ ID NO:22; and ii) one or more delivery moieties represented by the formula: wherein: A is a bond; p and q are the same or different and each is an integer from 1 to 12; provided that the sum of p and q is in the range from 6 to 18; R R R R R or R R wherein the decoy nucleic acid sequence is complexed with the one or more delivery moieties.