Patent ID: 9737891
Date: 2017-08-22
CPC Classifications: B01L,C12Q,G01N

Claim:
1. A method for operating a thermocycler instrument for amplification by a polymerase chain reaction, comprising the steps of: a) operating the thermocycler instrument including: for causing at least one sample in the sample tube contained in the sample holder to undergo polymerase chain reaction amplification by repealed cycling between at least a denaturation heating stage and an annealing cooling stage; b) monitoring a first temperature corresponding with a temperature of the sample holder using the at least one first temperature sensor, and a second temperature corresponding with a temperature of the at least one heat exchanger and external of the sample holder using the at least one second temperature sensor, and wherein substantially real time temperature condition information obtained from the at least one first temperature sensor and the at least one second temperature sensor is employed and processed for delivering suitable power; c) dynamically controlling the power that is delivered to the pair of thermoelectric devices of the thermocycler instrument based upon the first temperature and the second temperature, wherein the dynamically controlling step (c) includes the steps of: