Patent ID: 9567328
Date: 2017-02-14
CPC Classifications: A61P,C07D

Claim:
1. A compound selected from the group consisting of: 1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-1H-indole-5-carboxylic acid; 1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-(2-chloro-5-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(2-bromo-5-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-[2-bromo-5-(2-ethyl-butoxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-[2-chloro-5-(2-ethyl-butoxy)-benzyl]-1H-indazole-6-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-1H-indazole-4-carboxylic acid; 1-(2-benzyloxy-5-chloro-benzyl)-1H-indazole-5-carboxylic acid; 1-[5-chloro-2-(4-chloro-benzyloxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-(5-chloro-2-cyclopentylmethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-chloro-2-cyclopropylmethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(2-benzyloxy-5-bromo-benzyl)-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(4-chloro-benzyloxy)-bnzyl]-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-cyclopentylmethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-cyclopropylmethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(2-(trifluoromethyl)-5-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-cyclopropyl-2-methylmethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(2-isobutoxy-5-trifluoromethoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-3-methyl-1H-indazole-5-carboxylic acid; 1-(2-isobutoxy-5-trifluoromethoxy-benzyl)-3-methyl-1h-indazole-5-carboxylic acid; 1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-3-methyl-1H-indazole-5-carboxylic acid; 1-(5-chloro-2-isobutoxy-benzyl)-3-methyl-1H-indazole-5-carboxylic acid; 1-(2-isobutoxy-5-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carboxylic acid; 1-[2-(2-ethyl-butoxy)-5-trifluoromethyl-benzyl]-3-methyl-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(2-ethyl-butoxy)-benzyl]-3-methyl-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(1-methyl-cyclopropylmethoxy)-benzyl]-3-methyl-1H-indazole-5-carboxylic acid; 1-[5-chloro-2-(1-methyl-cyclopropylmethoxy)-benzyl]-3-methyl-1H-indazole-5-carboxylic acid; 1-[2-(4-chloro-benzyloxy)-5-trifluoromethyl-benzyl]-1H-indazole-5-carboxylic acid; 1-(2-cyclopentylmethoxy-5-trifluoromethyl-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-chloro-2-cyclopropylmethoxy-benzyl)-1H-indazole-4-carboxylic acid; 1-(5-chloro-2-isobutoxy-benzyl)-1H-indazole-4-carboxylic acid; 1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-1H-indazole-4-carboxylic acid; 1-[5-chloro-2-(4-chloro-benzyloxy)- benzyl]-1H-indazole-4-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-1H-indazole-6-carboxylic acid; 1-(5-bromo-2-cyclopentylmethoxy-benzyl)-1H-indazole-6-carboxylic acid; 1-[5-chloro-2-(2-ethyl-butoxy)-benzyl]-1H-indazole-6-carboxylic acid; 1-(5-chloro-3-fluoro-2-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(4,5-dichloro-2-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(1-ethyl-propoxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(2,2-dimethyl-propoxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(2-hydroxy-2-methyl-propoxy)-benzyl]-1H-indazole-5-carboxylic acid; 1-(5-hydroxy-2-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-[5-(2,2-difluoro-ethoxy)-2-isobutoxy-benzyl]-1H-indazole-5-carboxylic acid; 1-(5-difluoromethoxy-2-isobutoxy-benzyl)-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-3-ethyl-1H-indazole-5-carboxylic acid; 1-[5-bromo-2-(2-ethyl-butoxy)-benzyl]-3-ethyl-1H-indazole-5-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-2-methyl-1H-indole-5-carboxylic acid; 1-(5-bromo-2-isobutoxy-benzyl)-1H-indole-5-carboxylic acid; 1-[5-bromo-2-(2-ethyl-butoxy)-benzyl]-2-methyl-1H-indole-5-carboxylic acid; 1-[5-bromo-2-(2-ethyl-butoxy)-benzyl]-1H-indole-5-carboxylic acid; 1-[5-bromo-2-(2-ethyl-butoxy)-benzyl]-1H-indole-6-carboxylic acid; 1-(2-isobutoxy-5-trifluoromethoxy-benzyl)-1H-indole-5-carboxylic acid; 1-(2-isobutoxy-5-trifluoromethoxy-benzyl)-3-methyl-1H-indole-5-carboxylic acid; and 1-[2-(2-ethyl-butoxy)-5-trifluoromethoxy-benzyl]-3-methyl-1H-indole-5-carboxylic acid; or a pharmaceutically acceptable salt thereof.