Patent ID: 9725529
Date: 2017-08-08
CPC Classifications: A61K,B01J,C08F

Claim:
1. A biocompatible catalyst for a Copper (I) Catalyzed Azide-Alkyne Cycloaddition click reaction for functionalizing polymerizable liposomes comprising: Cu(I); and a Cu(I) stabilizing ligand, wherein the Cu(I) stabilizing ligand comprises a water-soluble triazole or oligo-triazole ligand comprising a ligand selected from the group consisting of wherein R wherein the catalyst is formed by addition of the water soluble triazole or oligo-triazole ligand and ascorbic acid to copper sulfate, wherein the click reaction comprises: functionalizing the polymerized clickable liposomes with at least one clickable group chosen from an azido group and an ethynyl group in the presence of the catalyst, and wherein the Cu(I) and the Cu(I) stabilizing ligand form a complex.