Patent ID: 9593376
Date: 2017-03-14
CPC Classifications: A61P,C12Q,Y10T

Claim:
1. A method of treating a human subject having a gastrointestinal stromal tumor (GIST), the method comprising measuring the relative amount of NKp30c, NKp30b, and NKp30a RNA transcript isoforms in a natural killer (NK) cell sample or in a peripheral mononuclear cell sample comprising NK cells obtained from the human subject; detecting a higher amount of NKp30c RNA transcript isoform than NKp30b and NKp30a RNA transcript isoforms in said NK cell sample or said peripheral mononuclear cell sample comprising NK cells; and administering to the human subject having a higher amount of NKp30c RNA transcript isoform a pharmaceutical composition comprising trichostatin A (TSA) or 5-azacitidine.