Patent ID: 9633575
Date: 2017-04-25
CPC Classifications: A61K,A61P,G01G,G09B,G16H

Claim:
1. A method of treating a subject at increased risk of a major adverse cardiovascular event for overweight or obesity comprising: selecting an overweight or obese subject who has been identified has being at increased risk of a major adverse cardiovascular event; and administering to said subject a therapeutically effective amount of 32 mg sustained release naltrexone per day, or a pharmaceutically acceptable salt thereof, and 360 mg sustained release bupropion per day, or a pharmaceutically acceptable salt thereof; wherein said overweight or obese subject is identified as being at increased risk of a major adverse cardiovascular event if said subject is diagnosed as having cardiovascular disease with at least one risk factor selected from the group consisting of: >50% stenosis of a coronary, carotid, or lower extremity artery within prior 2 years of said identification.