Patent ID: 9693970
Date: 2017-07-04
CPC Classifications: A61K,A61P

Claim:
1. A transdermal drug delivery system comprising: a backing layer; a drug-containing matrix layer; and a release layer, wherein the drug-containing matrix layer comprises: (a) donepezil or a pharmaceutically acceptable salt thereof as an active ingredient; (b) an acrylate-rubber hybrid as an adhesive; (c) an absorption enhancer; and (d) a crystallization-inhibiting agent, wherein: the transdermal drug delivery system has an increased skin penetration rate; donepezil or its pharmaceutically acceptable salt is in an amount of 10 to 20% by weight of the total weight of the drug-containing matrix layer; the absorption enhancer is in an amount of 5 to 15% by weight of the total weight of the drug-containing matrix layer; and the crystallization-inhibiting agent is in an amount of 1 to 10% by weight of the total weight of the drug-containing matrix layer.