Patent ID: 9546366
Date: 2017-01-17
CPC Classifications: C12N,C12Q,G01N

Claim:
1. A pharmaceutical composition for use in prophylaxis and/or therapy of cancer, the composition comprising one or more of: i) a polynucleotide encoding an shRNA comprising the sequence of SEQ ID NO:21 (ACUACGAACUGCCGUGGGUUGNNNNNNNNNCAACCCACGGCAGUUCGUAGU); ii) a polynucleotide encoding an shRNA comprising the sequence of SEQ ID NO:24 (GUCCCGCUGUGCAGUCCUCCGGUACACAANNNNNNNNNUUGUGUACCGGAGGACUGCACAGCGGGAC); iii) a polynucleotide comprising SEQ ID NO:18 (aCAGGUGAGGUUCCUGggagcc), iv) a polynucleotide comprising SEQ ID NO:19 (aCAGGUGAGGCUCCUGggagcc), v) a polynucleotide comprising the sequence of SEQ ID NO:21 (ACUACGAACUGCCGUGGGUUGNNNNNNNNNCAACCCACGGCAGUUCGUAGU), or vi) a polynucleotide comprising the sequence of SEQ ID NO:24 (GUCCCGCUGUGCAGUCCUCCGGUACACAANNNNNNNNNUUGUGUACCGGAGGACUGCACAGCGGGAC).