Patent ID: 9700563
Date: 2017-07-11
CPC Classifications: A61K,C07D

Claim:
1. A method of treatment of a disorder or condition in a mammal, selected from the group consisting of chronic cancer pain, pain from post-traumatic nerve damage, diabetic neuropathy pain, chronic primary pain, fibromyalgia, post-surgical pain, chronic visceral pain, chronic headache, pain from orofacial disorders, pain from musculoskeletal disorders, spinal cord injury pain and musculoskeletal pain, the method comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: X or X R5, R6 and R7 are independently selected from the list consisting of H, C R5 and R6, taken together with the N—C═N group to which they are attached, form a 4-10 membered cyclic or bicyclic ring, wherein up to two carbon atoms are replaced with heteroatoms selected from the group consisting of N, O and S; or R6 and R7 taken together with the nitrogen atom to which they are attached form a 4-10 membered cyclic or bicyclic ring, wherein up to two carbon atoms are replaced with heteroatoms selected from the group consisting of N, O and S or form a ring selected from azetidine, pyrrolidine, piperidine, azepine, piperazine, morpholine, thiomorpholine, oxazole and thiazole; X R1 and R2 are independently hydrogen or methyl; R3 is hydrogen; and n is zero, one or two.