Patent ID: 9702008
Date: 2017-07-11
CPC Classifications: C12Q,G16B

Claim:
1. A method of diagnosing and/or predicting the state of health in a subject comprising the steps: (a) providing a RNA sample from said subject, wherein said sample is a blood cell sample, (b) providing means for determining an expression profile for a plurality of miRNA and/or other non-coding RNA molecules, wherein said means are: (c1) determining the expression profile of a plurality of miRNAs and/or other noncoding RNAs in the sample of (a), by: (c2) determining the expression profile of a plurality of miRNA and/or non-coding RNA molecules by: (d) comparing a predetermined subset of miRNAs and/or other non-coding RNAs in said miRNA and/or other non-coding RNA expression profile, wherein said subset is characteristic for a particular condition to a corresponding subset of miRNAs and/or other non-coding RNAs in reference miRNA and/or non-coding RNA expression profiles obtained from a plurality of different reference subjects representing a plurality of different conditions, and (e) calculating the probability value of said subject for the particular conditions, and (f) optionally repeating steps (d) and (e) for at least one different particular condition, and/or (g) optionally collecting the probability values for the particular condition to diagnose and/or predict the health state of said subject.