Patent ID: 9732140
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07K

Claim:
1. A protein encoded by a nucleic acid comprising a start codon operatively linked to a sequence encoding a soluble CD83 protein of CD83 family of proteins selected from the group consisting of: i) a soluble CD83 protein consisting of amino acid residues 20 to 144 of SEQ ID NO:2; and ii) a soluble CD83 protein consisting of amino acid residues 20 to 145 of SEQ ID NO:2; wherein in each of i) and ii) the third or fifth cysteine residue is substituted with an amino acid residue selected from the group consisting of serine, alanine, glycine, valine, threonine, aspartic acid, glutamic acid, arginine, lysine, asparagine, and glutamine; wherein said third cysteine residue corresponds to residue 100 of SEQ ID NO:2, and wherein said fifth cysteine residue corresponds to residue 129 of SEQ ID NO:2.