Patent ID: 9585869
Date: 2017-03-07
CPC Classifications: A61K,A61P,C07C,C07D

Claim:
1. A method for modulating voltage-gated sodium and/or calcium channels, comprising the step of administering to a patient in need thereof an effective amount of a compound of formula (I): wherein: X is —O—; Y is hydrogen, —OH or —O(C Z is ═O or ═S; R is —(C R group where R R R R its pharmaceutically acceptable salts and the isolated optical isomers or mixtures of optical isomers of the compound and their pharmaceutically acceptable salts, wherein a disease treatable by such modulation is a neurological disorder selected from the group consisting of pain, migraine, Alzheimer's disease, Parkinson's disease, epilepsy, restless legs syndrome, cerebral ischemia, dementia conditions such as Lewy's body, fronto-temporal dementia and tautopathies, amyotrophic lateral sclerosis, parkinsonian syndromes, spino-cerebellar degeneration, Charcot-Marie-Toot neuropathies, traumatic brain injury, stroke and cerebral ischemia.