Patent ID: 9676866
Date: 2017-06-13
CPC Classifications: A61K,A61P,C07K

Claim:
1. An isolated monoclonal antibody, or an antigen-binding antibody fragment, that binds cell-associated CA 125/O772P polypeptide and comprises (a) a VH CDR1 sequence of SEQ ID NO:21, (b) a VH CDR2 sequence of SEQ ID NO:22, (c) a VH CDR3 sequence of SEQ ID NO:23, (d) a VL CDR1 sequence of SEQ ID NO:24, (e) a VL CDR2 sequence of SEQ ID NO:25, and (f) a VL CDR3 sequence of SEQ ID NO:26, wherein the sequence of (a)-(e) and (f) has less than 4 conservative substitutions.