Patent ID: 9663586
Date: 2017-05-30
CPC Classifications: A61K,A61P,C07K

Claim:
1. An isolated monoclonal antibody, or antigen binding fragment thereof, wherein said monoclonal antibody, or antigen binding fragment thereof, binds to an epitope of SOD1 protein and wherein said monoclonal antibody comprises a heavy chain variable domain and a light chain variable domain, wherein the heavy chain variable domain comprises a CDRH1, CDRH2, and CDRH3, wherein: (a) the CDRH1 comprises an amino acid sequence of SEQ ID NO:75; (b) the CDRH2 comprises an amino acid sequence of SEQ ID NO:77; and (c) the CDRH3 comprises an amino acid sequence of SEQ ID NO:79; and wherein the light chain variable domain comprises a CDRL1, CDRL2, and CDRL3, wherein: (d) the CDRL1 comprises an amino acid sequence of SEQ ID NO: 83; (e) the CDRL2 comprises an amino acid sequence of SEQ ID NO: 85; and (f) the CDRL3 comprises an amino acid sequence of SEQ ID NO: 87.