Patent ID: 9574166
Date: 2017-02-21
CPC Classifications: C12M

Claim:
1. A bioreactor adapted for rotation, the bioreactor comprising: an incubation chamber comprising a substantially closed confinement limited by a first semipermeable membrane at one end of the incubation chamber, a reservoir for housing an aqueous liquid in an interior of the reservoir, the reservoir comprising a second semipermeable membrane arranged in fluid contact with the interior of the reservoir, and a conduction volume housing a gaseous atmosphere and extending between the first semipermeable membrane of the incubation chamber and the second semipermeable membrane of the reservoir, and comprising a ventilation means comprising a pump in fluid connection with an inlet opening and arranged to pump air from the atmosphere surrounding the bioreactor into the conduction volume, and an outlet opening permitting air to escape from the conduction volume, wherein said first semipermeable membrane is permeable to oxygen and carbon dioxide so as to facilitate aeration of the incubation chamber and the second semipermeable membrane is permeable to water vapor, oxygen, and carbon dioxide, and wherein the second semipermeable membrane has a permeability to water vapor that is greater than a permeability to water vapor of the first semipermeable membrane.