Patent ID: 9719999
Date: 2017-08-01
CPC Classifications: G01N

Claim:
1. A method for determining an absence of coronary artery disease (CAD) in a subject, the method comprising: (a) measuring the concentration of at least one of Troponin I (cTnI) and cardiac troponin T (cTnT) in a blood, serum or plasma sample from the subject in an assay comprising counting individual digital events representing binding of a binding partner the at least one of cTnI and cTnT, wherein each individual digital event comprises a signal representing a single molecule of the cTnI and cTnT in the sample, determining a total signal as a sum of the individual digital events, and relating the sum to the concentration of the at least one of cTnI and cTnT in the sample, (b) determining an absence of CAD in the subject when the concentration of the at least one of cTnI and cTnT in the sample is less than about 10 pg/mL.