Patent ID: 9561303
Date: 2017-02-07
CPC Classifications: A61F,A61L

Claim:
1. A biocompatible composition for tissue repair or regeneration in mammals comprising: 40 to 80 wt % B 2.5 to 50 wt % CaO; one or more of MgO, SrO, and combinations thereof in a cumulative concentration of 5 to 40 wt %; one or more of Li one or more director elements selected from the group consisting of Cu, Zn, Fe, Mn, Ba, Co, S, V, and/or Y in a cumulative concentration between 0.05 and 5 wt % to promote in vivo calcium compound formation of calcium carbonate or other calcium-containing materials other than hydroxyapatite; wherein upon direct application of the biocompatible composition to a mammalian host, calcium carbonate or other calcium-containing materials other than hydroxyapatite form upon bioreaction of the composition with bodily fluids; wherein the composition is in a form of one or more of fibers, hollow fibers, tubes, ribbons, solid spheres, hollow spheres, particles, bonded particles, and combinations thereof assembled in a scaffold which has a porosity of between about 15 and about 90 vol % with at least about 75 vol % of pores being interconnected and suitable for application to a mammalian host such that it is exposed to the mammalian host's bodily fluids for tissue repair or regeneration in mammals; and wherein the composition is not water soluble.