Patent ID: 9744133
Date: 2017-08-29
CPC Classifications: A61K,A61P

Claim:
1. A liquid oral pharmaceutical composition comprising: (i) from about 0.1% to about 20% w/v polyvinylpyrrolidone; (ii) from about 5% to about 70% w/v polyethylene glycol; (iii) from about 1% to about 30% w/v propylene glycol; (iv) from about 1% to 10% w/v guaifenesin; and (v) from about 0.01% to about 1.0% w/v phenylephrine; further comprising one or more additional pharmaceutical agent selected from the group consisting of analgesics, decongestants, expectorants, antitussives, antipyretics, anti-inflammatory agents, cough suppressants, and antihistamines; and wherein the composition comprises about less than 2% total phenylephrine degradants, as a percent weight over weight phenylephrine, and about less than 2% loss of phenylephrine from the initial total phenylephrine content, measured over a 3 month time period while stored at 40° C. and 75% relative humidity.