Patent ID: 9624543
Date: 2017-04-18
CPC Classifications: C12Q

Claim:
1. A method of diagnosing and treating antibiotic responsive acute pulmonary exacerbation in a human patient having cystic fibrosis, the method comprising: a. obtaining a first blood sample from the patient prior to administration of an antibiotic therapy; b. administering the antibiotic to the patient; c. obtaining a second blood sample from the patient following administration of the antibiotic therapy; d. detecting the level of mRNA expression of CD64, IL32, PLXND1, HCA112, TLR2, and CD163 genes in both blood samples from steps (a) and (c); e. diagnosing the patient as having antibiotic responsive acute pulmonary exacerbation when the mRNA expression levels from step (a) and step (c) are different; and f. administering an effective amount of an antibiotic to the diagnosed patient.