Patent ID: 9724664
Date: 2017-08-08
CPC Classifications: B01J

Claim:
1. A spray-drying process, comprising: (a) providing a feed suspension in a tank at a temperature T (b) flowing said feed suspension from said tank through a heat exchanger comprising a feed suspension inlet and a spray solution outlet to form a spray solution, wherein said spray solution at said spray solution outlet is at a temperature T (c) directing said spray solution to a spray-drying apparatus via a flash nozzle having a central tube and an outer tube positioned proximate said spray solution outlet of said heat exchanger, wherein said spray solution is delivered through the central tube of said flash nozzle at a temperature T (d) atomizing said spray solution into droplets within said spray-drying apparatus through said flash nozzle to remove at least a portion of said organic solvent from said droplets to form a plurality of particles having an average diameter ranging from 0.5 μm to 500 μm, wherein said particles comprise a homogeneous solid amorphous dispersion of said active agent and said matrix material, wherein said spray solution is at said temperature T