Patent ID: 9597344
Date: 2017-03-21
CPC Classifications: A61K

Claim:
1. A liposome comprising: a lipid bilayer; a sonosensitizer that is disposed in the lipid bilayer; and an active agent contained in an interior space of the liposome, an interior of the lipid bilayer, or both, wherein the sonosensitizer self-assembles to form aggregates and the active agent is released when the liposome is exposed to ultrasound, and wherein the sonosensitizer has a structural formula of wherein C 1 is a C 8 -C 40 alkyl group, B 1 is —NH—C(O)—NH—, —NH—C(O)—, —CH(COOH)—, or —NH—C(O)—O—, and D 1 is