Patent ID: 9556191
Date: 2017-01-31
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound having Formula (I): or a stereoisomer, a geometric isomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof, wherein R is wherein each X and X X X each Y, Y Y each Y wherein each R each R each R each d is independently 0, 1, 2, 3, 4 or 5; e is 0, 1, 2, or 3; f is 0 or 1; L is a bond, O or S; R R each of R R Ar is wherein each R k is 0, 1, 2, 3, 4 or 5; and R wherein optionally each of alkyl, alkoxy, alkoxyalkyl, alkylamino, alkylaminoalkyl, heteroalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, cycloalkylalkenyl, cycloalkylalkynyl, cycloalkyloxyalkynyl, heterocyclyl, heterocyclylalkyl, heterocyclylalkenyl, heterocyclylalkynyl, fused bicyclyl, fused bicyclylalkyl, fused bicyclylalkenyl, fused bicyclylalkynyl, fused heterobicyclyl, fused heterobicyclylalkyl, fused heterobicyclylalkenyl, fused heterobicyclylalkynyl, spiro bicyclyl, spiro bicyclylalkyl, spiro bicyclylalkenyl, spiro bicyclylalkynyl, spiro heterobicyclyl, spiro heterobicyclylalkyl, spiro heterobicyclylalkenyl, spiro heterobicyclylalkynyl, aryl, aryloxy, arylalkyl, arylalkoxy, arylamino, heteroaryl, heteroarylalkyl, heteroarylalkoxy, heteroaryloxy, alkylthio, alkylcarbonyl, alkylacylamino, alkylsulfonyl, haloalkyl and alkylsulfinyl is independently substituted with one or more substituents independently selected from D, F, Cl, Br, I, —OH, —NO