Patent ID: 9683046
Date: 2017-06-20
CPC Classifications: A61K,A61P,C07K

Claim:
1. An isolated nucleic acid molecule, selected from the group consisting of (i) the light chain nucleotide sequence of SEQ ID NO: 163 and/or the heavy chain nucleotide sequence of SEQ ID NO: 164; (ii) a nucleotide sequence encoding the light chain variable region amino acid sequence of SEQ ID NO: 143 and/or a nucleotide sequence encoding the heavy chain variable region amino acid sequence of SEQ ID NO: 133; (iii) a nucleotide sequence encoding the light chain variable region amino acid sequence of SEQ ID NO: 127 and/or a nucleotide sequence encoding the heavy chain variable region amino acid sequence of SEQ ID NO: 126; (iv) a nucleotide sequence encoding the light chain variable region amino acid sequence selected from the group consisting of SEQ ID NOs: 137-144 and 148 and/or a nucleotide sequence encoding the heavy chain variable region amino acid sequence selected from the group consisting of SEQ ID NOs: 128-136 and 145-147; and (v) a nucleotide sequence encoding the light chain variable region amino acid sequence of SEQ ID NO: 143, a nucleotide sequence encoding the heavy chain variable region amino acid sequence of SEQ ID NO: 133, a nucleotide sequence encoding the IgG4 heavy chain constant region amino acid sequence of SEQ ID NO: 159, and a nucleotide sequence encoding the IgG4 light chain constant region amino acid sequence of SEQ ID NO: 160.