Patent ID: 9566239
Date: 2017-02-14
CPC Classifications: A61K

Claim:
1. A powder for use in a dry powder inhaler, the powder comprising: i) a fraction of fine particle size constituted of a mixture prepared by co-micronising a physiologically acceptable excipient and an additive, the mixture having a mean particle size of less than 35 μm; ii) a fraction of coarse particles constituted of a physiologically acceptable carrier having a diameter of at least 100 μm; and iii) at least one active ingredient having a particle size of less than 10 μm; said mixture (i) being composed of up to 99% by weight of particles of the physiologically acceptable excipient and at least 1% by weight of additive and a ratio between the fine excipient particles and the coarse particles being between 1:99 and 40:60% by weight, and wherein the additive partially coats the surfaces of both the physiologically acceptable excipient and the coarse particles.