Patent ID: 9733165
Date: 2017-08-15
CPC Classifications: B01L,C12N,G01N

Claim:
1. A device for isolating a biological cell present within a biofluid, the device comprising a flow channel enclosed within walls and having a portion comprising a plurality of features configured to impede movement of a biological cell in the biofluid in a direction while allowing flow of the biofluid in the direction, at least one of the plurality of features comprising an aperture having a first dimension and a second dimension, the first dimension being smaller than a smallest dimension of the biological cell and the second dimension being equal to a dimension of the portion of the flow channel, wherein at least some of the plurality of features (1) are arranged to partition the flow channel into a first flow conduit and a second flow conduit and (2) include apertures having longitudinal axes being oriented at an angle to a main axis of flow in the first flow conduit.