Patent ID: 9702849
Date: 2017-07-11
CPC Classifications: B82Y,C12Q,G01N

Claim:
1. A nanopore sensor comprising: a nanopore disposed in a support structure; a fluidic connection between a first fluidic reservoir and an inlet to the nanopore, with a first ionic solution of a first ionic concentration disposed in the first reservoir; a fluidic connection between a second fluidic reservoir and an outlet from the nanopore, with a second ionic solution of a second ionic concentration, different than the first ionic concentration, disposed in the second reservoir, the nanopore providing the sole path of fluidic communication between the first and second reservoirs; an electrical transduction element disposed in contact with that ionic solution, of the first and second ionic solutions, which has a lower ionic concentration, the transduction element being arranged at a site that produces in the transduction element an electrical signal indicative of electrical potential local to that ionic solution having a lower ionic concentration; and an electrical circuit connected to the transduction element and including a circuit element that produces an electrical signal indicative of changes in the electrical potential local to that ionic solution having a lower ionic concentration.