Patent ID: 9539214
Date: 2017-01-10
CPC Classifications: A61K,A61P

Claim:
1. A method for delivering a pharmaceutical composition to a patient in need thereof, comprising administering to said patient a pharmaceutical composition in unit dose form comprising acetylsalicylic acid, or pharmaceutically acceptable salt thereof, and omeprazole, or pharmaceutically acceptable salt thereof, wherein said omeprazole, or pharmaceutically acceptable salt thereof, wherein said omeprazole, or pharmaceutically acceptable salt thereof is an immediate release omeprazole, or pharmaceutically acceptable salt thereof and is released from said unit dose form at a pH of from about 0 or greater to target a mean time at which intragastric pH remains at about 4.0 or greater for about a 24 hour period after reaching steady state of at least about 50% and wherein one unit dose form is administered to target: i) a pharmacokinetic (pk) profile for acetylsalicylic acid where: ii) a pharmacokinetic (pk) profile for omeprazole where the dose has a mean area under the plasma concentration-time curve from time zero when the dose is administered to about 12 hours after the dose is administered (AUC