Patent ID: 9605298
Date: 2017-03-28
CPC Classifications: B01L,C12Q

Claim:
1. A system for sorting chromatin comprising: (a) a channel that is fluidically connected to a plurality of downstream flow paths, said channel being adapted to hold said chromatin in a continuous liquid body in said channel; (b) one or more light sources configured to illuminate the channel to create one or more interrogation volumes, wherein the one or more interrogation volumes are bounded by a submicrometer channel region of said channel, and wherein the one or more interrogation volumes are each less than 0.5 femtoliters; (c) a detection module configured to detect at least two types of signals indicative of two distinct properties of the chromatin in the one or more interrogation volumes; (d) a sorting module configured to direct the chromatin to one of the plurality of downstream flow paths based on the two distinct properties indicated by said two types of signals; and (e) one or more electrodes in electrical connection by fluid with the channel and downstream flow paths to direct the chromatin.