Patent ID: 9693955
Date: 2017-07-04
CPC Classifications: A61K,A61M,A61P,Y10T

Claim:
1. Aerosolized particles ready for administration to a patient needing such administration, comprising at least one therapeutically active substance and obtained by the following steps: a. providing essentially dry inhalable particles comprising the at least one therapeutically active substance, the essentially dry inhalable particles having a first desired mass mean aerodynamic diameter (MMAD) suitable for an intended administration to a patient, b. suspending the particles of step (a) in a carrier gas to obtain a first aerosol with aerosolized essentially dry inhalable particles at the first MMAD, c. adding water vapor to the first aerosol to obtain a second aerosol having a higher water content than the first aerosol, and d. adjusting the temperature and/or the pressure of the second aerosol as to exceed the second aerosol's dew point and to cause condensation of water on the particles, so as to increase the first MMAD of the aerosolized particles to a second MMAD, which second MMAD remains suitable for the intended administration, wherein the at least one therapeutically active substance includes lung surfactant.