Patent ID: 9579386
Date: 2017-02-28
CPC Classifications: A61J,A61K,A61P,B82Y,C07C,Y10S

Claim:
1. A therapeutic nanoparticle comprising: about 4 to about 25 weight percent of a therapeutic agent; about 10 to about 99 weight percent of a diblock poly(lactic) acid-poly(ethylene)glycol copolymer comprising poly(lactic) acid having a number average molecular weight of about 15 to 20 kDa, and poly(ethylene)glycol having a number average molecular weight of about 4 to 6 kDa; wherein the hydrodynamic diameter of the therapeutic nanoparticle is about 60 nm to about 140 nm; and wherein the therapeutic nanoparticles releases less than 2% of the therapeutic agent over about one minute when placed in a phosphate buffer solution at 37° C.