Patent ID: 9656261
Date: 2017-05-23
CPC Classifications: B01L,G01N

Claim:
1. A microfluidic chip, comprising: an inlet configured to receive a template DNA extracted from a sample acceptor that is external of the microfluidic chip and is fluidically coupled to the microfluidic chip on a cartridge; a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, the first domain including a thermal-coupler reservoir coupled with a PCR reservoir for PCR amplification, thermal cycles in the PCR reservoir being induced based on temperature measured from the thermal-coupler reservoir; a dilution domain having a reservoir that is fluidically coupled to the first domain and is configured to dilute a PCR mixture received from the first domain with a dilutant in the reservoir; and a second domain that is fluidically coupled to the dilution domain so as to receive the amplified DNA fragments, the second domain including a separation channel that is configured to perform electrophoretic separation of the amplified DNA fragments.