Patent ID: 9717756
Date: 2017-08-01
CPC Classifications: A61K

Claim:
1. A method of treating pain or inflammation associated with a traumatic brain injury or spinal cord injury, the method comprising delivering to a subject in need thereof a first dose comprising a therapeutically effective amount of at least one biomembrane sealing agent comprising polyethylene glycol (PEG) and a therapeutically effective amount of at least one bioactive agent comprising magnesium, and delivering to the subject in need thereof a second dose of the PEG and the magnesium after the first dose, wherein the at least one biomembrane sealing agent is delivered in an injectable composition, and the at least one biomembrane sealing agent comprises from about 15% to about 30% weight/volume of the injectable composition, and the injectable composition further comprises an antioxidant, and the PEG is PEG3350, and the first dose is delivered 15 minutes post-injury and the second dose is delivered 6 hours after the first dose, and the first dose and the second dose combined is 1.4 g/kg of PEG and 0.230 mmol/kg of magnesium.