Patent ID: 9700621
Date: 2017-07-11
CPC Classifications: A61K,A61N,A61P

Claim:
1. A method for inducing in vitro, ex vivo or in vivo the perturbation, lysis or destruction of target human cells selected from the group consisting of benign cells, pre-malignant cells and malignant cells, comprising i) contacting said target cells with a population of metallic nanoparticles having a constant metal concentration per target cell, during a period of time sufficient to allow the nanoparticles to interact with said cells, each nanoparticle of the population being made of a metal having an atomic number (Z) of at least 25, each metallic nanoparticle of the population being covered with a biocompatible coating, and the mean largest size of the nanoparticles of the population being between 80 and 105 nm, and, ii) exposing the cells to ionizing electromagnetic radiation, said exposure inducing or causing the perturbation, lysis or destruction of said cells.