Patent ID: 9630970
Date: 2017-04-25
CPC Classifications: A61P,C07D

Claim:
1. A method of treating a TYK2-mediated disorder, disease, or condition in a patient wherein the disorder, disease, or condition is an autoimmune disorder selected from type 1 diabetes, systemic lupus erythematosus, multiple sclerosis, psoriasis, Crohn's disease, ulcerative colitis, and inflammatory bowel disease, comprising administering to said patient a compound of formula I, or a pharmaceutical composition thereof: or a pharmaceutically acceptable salt thereof, wherein: each of X and Y is independently ═C(R Ring A is phenyl; a 5-6 membered heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur; a 3-6 membered saturated or partially unsaturated heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, and sulfur; or a 4-6 membered saturated or partially unsaturated carbocyclic ring; wherein Ring A is substituted with m instances of R each of R each R R R R provided that when R each instance of R each instance of R L m is 0-4; n is 0-4; p is 0-6; and each R is independently hydrogen, or an optionally substituted group selected from C