Patent ID: 9739779
Date: 2017-08-22
CPC Classifications: C07K,C12Q,G01N

Claim:
1. A method for screening for a compound that inhibits Janus kinase 3 (Jak3) protein, comprising the steps of: selecting a potential inhibitory compound; contacting, a phosphate donor with a recombinant Jak3 protein and the potential inhibitory compound in a first sample; contacting said phosphate donor with the recombinant Jak3 protein in a second control sample wherein the recombinant Jak3 protein has a sequence of SEQ ID NO. 6 or SEQ ID No. 7; measuring a level of autophosphorylation of said Jak3 protein in the first sample and in the second sample; wherein a reduction in the level of Jak3 autophosphorylation in the first sample compared to the level in the second control sample indicates that the compound inhibits Jak3 protein.