Patent ID: 9636329
Date: 2017-05-02
CPC Classifications: A61K

Claim:
1. A method comprising: (a) requesting a test providing results of an analysis to detect GLUT4 in cancer cells from a biological sample obtained from a patient diagnosed with multiple myeloma, chronic lymphocyte leukemia (CLL), diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma, neuroblastoma, breast cancer, or ovarian cancer, and (b) administering a GLUT4 inhibitor and an OXPHOS inhibitor to the patient if an elevated level of the GLUT4 in the cancer cells is detected or if the GLUT4 is mislocalized in the cancer cells, wherein the GLUT4 inhibitor is selected from ritonavir and indinavir and the OXPHOS inhibitor is selected from metformin, phenformin, buformin, and pharmaceutically acceptable salts thereof.