Patent ID: 9724381
Date: 2017-08-08
CPC Classifications: A61K,C07K,Y02P

Claim:
1. A method for inhibiting ghrelin in a subject in need thereof, said method comprising the step of administering an effective amount of a ghrelin receptor antagonist, and wherein the ghrelin receptor antagonist is a peptide of formula (VII): A 11 -A 12 -A 13 -Gly-Ser-A 14 -Phe-Leu-A 15 -A 16 -A 17 -A 18 (SEQ ID NO: 93), wherein A 11 is an amino acid; A 12 is an amino acid; A 13 is an amino acid; each of A 15 , A 16 , A 17 , and A 18 is absent or an amino acid, and can be the same or different; A 14 is a serine conjugated with a —C(O)C 1 -C 20 alkyl group on the side chain OH of said serine or a diaminopropionic acid conjugated with a —C(O)C 1 -C 20 alkyl group on one of the amino groups of said diaminopropionic acid.