Patent ID: 9617531
Date: 2017-04-11
CPC Classifications: A61K,A61P,B82Y,C07K,C12N

Claim:
1. A fusion protein consisting of one cytokine moiety attached to a DDD (dimerization and docking domain) moiety, wherein the amino acid sequence of said DDD moiety is residues 1-44 of human PKA RIIα, wherein said DDD moiety is capable of forming a dimer that binds to an AD moiety to form a complex; and wherein the cytokine moiety is selected from the group consisting of IL-2, IL-3, IL-4, IL-5, IL-6, IL-9, IL-10, IL-11, IL-12, IL-13, IL-15, IL-16, IL-17, IL-18, RANTES, MIP-1A, MIP-1B, IP-10, GRO-β, interferon-α, interferon-β, G-CSF, GM-CSF, erythropoietin, thrombopoietin, and LIF.