Patent ID: 9731007
Date: 2017-08-15
CPC Classifications: A61K,A61P,C07K

Claim:
1. A chimeric fusion polypeptide comprising (i) a canine tumor necrosis factor receptor (TNFR) p80 extracellular domain polypeptide that specifically binds to canine TNF, or a canine TNF-binding fragment thereof, conjoined to (ii) a polypeptide comprising a CH2 constant domain and a CH3 constant domain of canine IgG immunoglobulin, wherein the p80 extracellular domain polypeptide comprises amino acid residues 23 to 260 of SEQ ID NO:14, or a sequence having at least 90% sequence identity thereto, wherein the N-terminal amino sequence of the chimeric fusion polypeptide comprises the N-terminal VPGQ motif of the p80 extracellular domain polypeptide.