Patent ID: 9694038
Date: 2017-07-04
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method for the systemic, multi-tiered treatment of patients suffering from brain disease of ischemia by delivering stem cells collected from umbilical cord tissue or umbilical cord blood, consisting of: a) selecting a patient displaying symptoms of brain ischemia; b) administering at least one dose consisting of an effective amount of stem cells collected from umbilical cord tissue or umbilical cord blood; where administration of said stem cells is intravenous, intrathecal, intra-arterial, via catheter into the organ, or by direct injection into the organ; c) monitoring the effectiveness of administration of said stem cells by a monitoring means that objectively measures blood flow and includes at least one of ultrasound, magnetic resonance angiogram and neuroimaging; d) determining, based on monitoring the effectiveness of stem cell treatment by said monitoring means, whether an additional dose of stem cells is indicated; and e) if necessary, repeating steps b) through d) until there is a clinical indication of amelioration of the symptoms of brain ischemia, or until there is contraindication to continued treatment; wherein the second dose of stems cells, if administered, is administered by a method that is at least as invasive as the method utilized for the administration of the previous dose of stem cells.