Patent ID: 9675645
Date: 2017-06-13
CPC Classifications: A61K,A61L

Claim:
1. A method for producing an implantable bone composition having enhanced osteoinductivity comprising the steps of: (a) providing a bone material in the form of a demineralized bone matrix comprising a plurality of fully demineralized, entangled bone fibers and surface demineralized bone chips; (b) dehydrating the bone material via critical point drying with a solvent at its critical point to remove moisture content from the demineralized bone matrix to approximately 8% or less to produce a dehydrated bone material having a surface area with a BET value from about 1 m 2 /gm to about 5 m 2 /gm; (c) disposing the dehydrated bone material within a polymer mesh; wherein the weight ratio of the fully demineralized bone fibers to the surface demineralized bone chips within the dehydrated bone material is about 1:0.2.