Patent ID: 9618485
Date: 2017-04-11
CPC Classifications: F04B,G01N

Claim:
1. A high performance liquid chromatography (HPLC) system, comprising: a separating device comprising a separating device inlet, a separating device outlet, and a stationary phase for separating compounds of a sample fluid carried in a mobile phase; a mobile phase drive comprising a mobile phase drive outlet in fluid communication with the separating device inlet, the mobile phase drive configured for driving the mobile phase through the separating device at a fluid pressure and a fluid flow rate; and a control unit in signal communication with the mobile phase drive, the control unit configured for: receiving a control value indicative of the fluid pressure in the mobile phase; and based on the control value, maintaining the fluid pressure at the separating device inlet substantially at a set value or within a range including the set value, by controlling the mobile phase drive to vary the fluid flow rate, wherein the control value is selected from the group consisting of: a pressure measured in the mobile phase; a pressure difference between the separating device inlet and the separating device outlet; a control parameter of the mobile phase drive; a temperature measured in the mobile phase; and a combination of two or more of the foregoing.