Patent ID: 9714938
Date: 2017-07-25
CPC Classifications: G01N

Claim:
1. A method of detecting an autoimmune disease state or autoimmune disease susceptibility in a mammalian subject, comprising detecting an antibody in a bodily fluid test sample from the subject, wherein the antibody is characteristic of or associated with an autoimmune disease and wherein it is not known whether the test sample comprises the antibody, the method comprising: (a) contacting the test sample with a plurality of different amounts of an antigen specific for the antibody, (b) detecting the amount of specific binding between the antibody and the antigen, (c) plotting or calculating a curve of the amount of specific binding versus the amount of antigen for each amount of antigen used in step (a), and (d) comparing the curve of the test sample with a control sample curve, wherein a difference in the test sample curve when compared with the control sample curve indicates the presence of autoimmune disease state or autoimmune disease susceptibility the subject.