Patent ID: 9532958
Date: 2017-01-03
CPC Classifications: A61J,A61K,A61P

Claim:
1. A method for producing powders for inhalation, comprising: a first mixing step of stirring a first active ingredient and a carrier in the presence of a milling medium, and mixing the first active ingredient and the carrier while crumbling agglomerates of the first active ingredient to obtain a mixture of the carrier and the first active ingredient; and a second mixing step of adding fine powders and a second active ingredient that is different from the first active ingredient to the mixture obtained in the first mixing step, and stirring and mixing the mixture and the fine powders in the presence of the milling medium, wherein the first active ingredient has higher cohesive property as compared with the second active ingredient, the carrier and the fine powders have the same composition, an average particle diameter of the fine powders is from 1/50 to ⅕ of an average particle diameter of the carrier, and the first active ingredient and the second active ingredient are homogenously distributed in the powders for inhalation.