Patent ID: 9744354
Date: 2017-08-29
CPC Classifications: A61B,A61N

Claim:
1. A method of delivering a respiratory therapy to a subject via a programmable neurostimulator communicating with a stimulation delivery lead implanted in the subject, the method comprising: titrating a stimulation setting of the neurostimulator while the subject is awake by delivering a first set of stimulation pulses at a plurality of first stimulation setting values between a lower limited defined by a capture threshold corresponding to a beneficial effect of the respiratory therapy and an upper limit defined by a comfort threshold corresponding to an unacceptable sensation experienced by the subject; and subsequently, while the subject is asleep, repeating the step of titrating the stimulation setting of the neurostimulator by delivering a second set of stimulation pulses at a plurality of second stimulation setting values, wherein one or more of the plurality of second stimulation setting values is different than one or more of the plurality of first stimulation setting values and the plurality of second stimulation setting values are between the lower limit defined by the capture threshold and a second upper limit defined by a threshold at which the patient is expected to at least partially arouse from sleep.