Patent ID: 9730899
Date: 2017-08-15
CPC Classifications: A61K,A61P

Claim:
1. A controlled release pharmaceutical composition, comprising a core comprising a pharmaceutical active ingredient, wherein: the core is coated with an ethanol resistance conferring coating layer, which confers ethanol resistance to a release profile of the pharmaceutical active ingredient under in-vitro conditions at pH 1.2 and/or at pH 6.8 in a buffered medium; wherein ethanol resistance means that the release profile is not accelerated by more than 20% and is not delayed by more than 20% under the influence of a 40% ethanol-containing medium in comparison to a release profile of a medium without ethanol; the coating layer comprises at least 70% by weight of a mixture of a polymeric portion a) and an excipients portion b); the polymeric portion a) comprises 60 to 99% by weight of a water insoluble, essentially neutral vinyl polymer or copolymer; and the excipients portion b) comprises: wherein the percent (%) by weight of each excipient is based on the dry weight of the polymeric portion a).