Patent ID: 9549900
Date: 2017-01-24
CPC Classifications: A61K,A61P

Claim:
1. A method of treating a human subject in need of melatonin therapy, the method comprising administering to a human subject a compressed tablet comprising an effective amount of melatonin, citric acid, and a cellulosic polymer that combine after ingestion to form an acidic hydrogel with an internal pH of less than 4.4 that dissolves the melatonin and is effective to provide a first release dose of melatonin for assisting in inducement of sleep and a subsequent sustained release dose of melatonin for assisting in sustaining sleep while in said human subject's gastrointestinal tract, and said composition releases approximately 50% of said melatonin in said composition into the gastrointestinal tract within approximately two hours after oral ingestion.