Patent ID: 9650670
Date: 2017-05-16
CPC Classifications: C12Q,G01N,H03F

Claim:
1. A patch clamp amplifier, comprising: an integrating operational amplifier having a first inverting input for receiving current from a nanopore sensor, said integrating operational amplifier further having a first non-inverting input and a first output; a feedback capacitor connecting said first output to said first inverting input; a feedback impedance in parallel with said feedback capacitor; a differentiator operational amplifier having a second inverting input, a second non-inverting input, and a second output; a first input capacitor connecting said second inverting input to said first output; a first input impedance in parallel with said first input capacitor; a second input capacitor connecting said second non-inverting input to said first non-inverting input; a second input impedance in parallel with said second input capacitor; a first resistor connecting said second output to said second inverting input; and a second resistor connecting said second non-inverting input to ground; wherein said feedback impedance is provided by a pseudo-resistor or an on-chip poly resistor.