Patent ID: 9695476
Date: 2017-07-04
CPC Classifications: C12Q

Claim:
1. An in vitro method or assay for the diagnosis of osteochondrosis or prediction of the likelihood of its onset in a terrestrian mammal, comprising the steps a) obtaining a sample from a horse, which is not more than 12 months old, b) measuring the expression level of a marker in the sample with an agent that can be used to determine the expression level of said marker, and c) comparing the expression level measured in step b) to the expression level of said marker measured in a sample obtained from one or more terrestrian mammals of the same species not affected by osteochondrosis, characterized in that the marker is ApoB-3G, wherein an increase in the expression level of ApoB-3G is indicative of osteochondrosis, and wherein ApoB-3G is eDNA synthesized using RNA extracted from the sample.