Patent ID: 9739698
Date: 2017-08-22
CPC Classifications: G01N,G02B

Claim:
1. An optical analysis device which detects light from light-emitting particles dispersed and moving at random in a sample solution using an optical system of a confocal microscope or a multiphoton microscope, comprising: a light detection region mover which moves a position of a light detection region of the optical system in the sample solution; a light detector which detects light from the light detection region; and a signal processor which generates time series light intensity data of the light from the light detection region detected with the light detector during the moving of the position of the light detection region in the sample solution and detects each of signals of the light-emitting particles individually in the time series light intensity data; wherein the signal processor measures successively an interval of generation times between the signals of individual light-emitting particles detected in the time series light intensity data one-by-one along time progress of the time series light intensity data, and determines an index value representing a concentration of the light-emitting particles using a plurality of the signal generation time intervals measured successively, and wherein an increase in the interval of generation times between the signals of the individual light-emitting particles detected in the time series light intensity data one-by-one along time progress of the time series light intensity data corresponds to a decrease in the concentration of the light-emitting particles, and vice versa.