Patent ID: 9677074
Date: 2017-06-13
CPC Classifications: A61K,A61P,C12N

Claim:
1. A method of upregulating a function of and/or the expression of a Insulin Receptor Substrate 2 (IRS2) polynucleotide in mammalian cells or tissues in vivo or in vitro comprising: contacting said cells or tissues with at least one antisense oligonucleotide of 10 to 30 nucleotides in length that targets, is 100% complementary to and specifically hybridizes to a complementary region of a natural antisense polynucleotide of the Insulin Receptor Substrate 2 (IRS2) polynucleotide consisting essentially of SEQ ID NO: 3; thereby upregulating a function of and/or the expression of the Insulin Receptor Substrate 2 (IRS2) polynucleotide in mammalian cells or tissues in vivo or in vitro.