Patent ID: 9725446
Date: 2017-08-08
CPC Classifications: A61K,A61P,C07D

Claim:
1. A compound of the formula I wherein R denotes isoquinolin-1-, -4-, -5- or -6-yl, which is unsubstituted or mono- or disubstituted by R R R R R R A denotes unbranched or branched alkyl having 1-6 C atoms, in which one or two CH A′ denotes unbranched or branched alkyl having 1-4 C atoms or Cyc, Cyc denotes cycloalkyl having 3, 4, 5, 6 or 7 C atoms, Ar denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, A, —[C(R Het denotes a mono- or bicyclic saturated, unsaturated or aromatic heterocycle having 1 to 4 N, O and/or S atoms which is unsubstituted or mono- or disubstituted by Hal, A, —[C(R Het′ denotes a monocyclic saturated heterocycle having 1 or 2 N, O and/or S atoms which is unsubstituted or mono- or disubstituted by A and/or ═O, Hal denotes F, Cl, Br or I, n denotes 0, 1 or 2, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios.