Patent ID: 9701990
Date: 2017-07-11
CPC Classifications: C12N,C12P

Claim:
1. A method of producing a highly unsaturated fatty acid by culturing a strain of Mortierella alpina capable of producing the highly unsaturated fatty acid in a culture medium containing at least a carbon source and a nitrogen source, using an aeration-agitation culture device capable of adjusting and controlling an agitation power and an aeration amount, the method comprising: performing mechanical agitation after start of a main culture, wherein the agitation power per unit liquid amount is 30-269 (W/m immediately before dissolved oxygen concentration value decreases to about 50% or 12 to 24 hours after start of the main culture, increasing aeration or agitation by adjusting and controlling at least any one of the maximum aeration amount and a maximum power required for agitation to a range which satisfies that KLA (=(P/V) thereby producing the highly unsaturated fatty acid from the main culture.