Patent ID: 9532988
Date: 2017-01-03
CPC Classifications: A61K,A61P

Claim:
1. A method of treating diabetic neuropathic pain in a subject in need thereof comprising administering to the subject the pharmaceutical composition comprising: (i) a transient receptor potential ankyrin-1 (“TRPA1”) antagonist compound which is N-{4-[2,4-difluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}-2-(1,3-dimethyl-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-5-yl)acetamide or a pharmaceutically acceptable salt thereof, and (ii) an analgesic agent which is duloxetine or a pharmaceutically acceptable salt thereof, wherein the TRPA1 antagonist and the analgesic agent are present in a weight ratio ranging from about 1:1 to about 1:10.