Patent ID: 9709568
Date: 2017-07-18
CPC Classifications: C07K,G01N

Claim:
1. An isolated antibody or antigen binding fragment thereof that specifically binds human programmed death ligand 1 (PD-L1) as set forth in SEQ ID NO: 37 and comprises three light chain CDRs of CDRL1, CDRL2 and CDRL3 and three heavy chain CDRs of CDRH1, CDRH2 and CDRH3, wherein: (a) CDRL1 is selected from the group consisting of SEQ ID NO:1, SEQ ID NO:9, and SEQ ID NO:21; (b) CDRL2 is SEQ ID NO:2; (c) CDRL3 is selected from the group consisting of SEQ ID NO:3, SEQ ID NO:10, and SEQ ID NO:22; (d) CDRH1 is selected from the group consisting of SEQ ID NO:5, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:26, and SEQ ID NO:27; (e) CDRH2 is selected from the group consisting of SEQ ID NO:6, SEQ ID NO:16, and SEQ ID NO:28; and (f) CDRH3 is selected from the group consisting of SEQ ID NO:7, SEQ ID NO:17, and SEQ ID NO:29.