Patent ID: 9592289
Date: 2017-03-14
CPC Classifications: A61K,C07K

Claim:
1. An antibody formulation comprising: a) about 20 mg/mL of a humanized IgG4 anti-CXCR5 (C-X-C chemokine receptor type 5) antibody comprising a heavy chain variable region comprising complementary determining regions (CDRs) comprising the amino acid sequences of SEQ ID NOS: 15, 16, and 17, and a light chain variable region comprising CDRs comprising the amino acid sequences of SEQ ID NOS: 18, 19, and 20; b) about 10 mM citrate buffer; c) about 0.02% polysorbate 20; d) about 6% sucrose; and e) about 0.2% sodium chloride; wherein the pH of the formulation is at or below the lower of about pH 6.0 and the pI of the binding agent.