Patent ID: 9733256
Date: 2017-08-15
CPC Classifications: A61K,A61P,G01N,Y10T

Claim:
1. A method, comprising obtaining a first biological sample from a subject having cancer prior to administering an anti-cancer agent comprising oxaliplatin or a salt thereof and fluorouracil or a salt thereof; administering the anti-cancer agent to the subject; obtaining a second biological sample from the subject after the administering, measuring a level of one or more substances selected from the group consisting of Asp, Gly, Arg, N-acetyl-β-alanine, N-acetylornithine, cadaverine, cysteic acid, 2-aminoadipic acid, GABA, γ-Glu-Cys, β-Ala-Lys, Glu-Glu, and S-lactoylglutathione, in the first and second biological samples, and continue administering the anti-cancer agent to the subject when the level of the one or more substances is increased in the second sample compared to the first sample or discontinuing the administration of the anti-cancer agent when the level of the one or more substances is decreased or unchanged in the second sample compared to the first sample.