Patent ID: 9623222
Date: 2017-04-18
CPC Classifications: A61K,A61M

Claim:
1. A drug depot for implantation at or near a target tissue site beneath the skin of a patient, the drug depot comprising a solid body comprising one or more immediate release layers that release a bolus dose of a drug and one or more sustained release layers that release a therapeutically effective amount of the drug and a polymer having an average molecular weight of about 10,000 to about 100,000, wherein the drug depot is attached to at least one line comprising a shape memory polymer and a coating comprising a drug, the at least one line having a distal end and a proximal end, the proximal end of the line attached to the drug depot; and the distal end of the line is attached to an anchor that is configured to limit movement of the drug depot at or near the target tissue site, wherein the anchor comprises a pellet that is rotatably attached to the line, the pellet comprising a cylindrical shape having a distal end defining a planar surface and a tapered proximal end, the pellet may be turned clockwise or counterclockwise when implanted so as to lodge the pellet at or near the target tissue site and the pellet comprising a polymer having an average molecular weight of about 10,000 to about 100,000, wherein the drug depot is capable of releasing the therapeutically effective amount of the drug over a period of at least one day, and wherein the line spaces the drug depot from the anchor by a distance of from about 0.1 mm to about 5 cm, and the line comprises a diameter smaller than the pellet and the drug depot.