Patent ID: 9700569
Date: 2017-07-11
CPC Classifications: A61K,A61P

Claim:
1. A method for the prophylaxis or treatment of hepatic fibrosis caused by infection with hepatitis virus, comprising administering an effective amount of a CBP/β-catenin inhibitor to a mammal, wherein the CBP/β-catenin inhibitor is either: 4-(((6S,9S,9aS)-1-(benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)octahydro-1H-pyrazino[2,1-c][1,2,4]triazin-6-yl)methyl)phenyl dihydrogen phosphate, or (6S,9S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide.