Patent ID: 9708354
Date: 2017-07-18
CPC Classifications: C07F

Claim:
1. A method for synthesizing N-palmitoyl-3-O-benzoyl-D-erythro-sphingomyelin, comprising allowing N-palmitoyl-3-O-benzoyl-D-erythro-ceramide to react with 2-chloro-2-oxo-1,3,2-dioxaphospholane in the presence of tetramethylethylenediamine to yield N-palmitoyl-3-O-benzoyl-1-O-(2-oxo-1,3,2-dioxaphospholan)-D-erythro-ceramide, and allowing N-palmitoyl-3-0-benzoyl-1-O-(2-oxo-1,3,2-dioxaphospholan)-D-erythro-ceramide to react with trimethylamine under conditions effective to yield N-palmitoyl-3-O-benzoyl-D-erythro-sphingomyelin; wherein N-palmitoyl-3-O-benzoyl-1-O-(2-oxo-1,3,2-dioxaphospholan)-D-erythro-ceramide is not purified or isolated.