Patent ID: 9700567
Date: 2017-07-11
CPC Classifications: A61K,A61P

Claim:
1. An implantable drug depot for reducing, preventing or treating pain and/or inflammation in a patient in need of such treatment, the implantable drug depot comprising dexamethasone in an amount from about 2 wt. % to about 30 wt. % of the drug depot, and at least one biodegradable material comprising a polymer gel comprising one or more of poly(lactide-co-glycolide) (PLGA), polylactide (PLA), polyglycolide (PGA), D-lactide, D,L-lactide, L-lactide, D,L-lactide caprolactone, D,L-lactide-glycolide-caprolactone or a combination thereof, wherein the drug depot is capable of releasing dexamethasone over a period of at least fifty days, and the polymer gel is an adherent gel that stiffens after delivery to a target site having a pre-dosed modulus of elasticity in the range of about 5×10 4 to about 1×10 5 dynes/cm 2 and a post-dosed modulus of elasticity in the range of about 2×10 5 to about 5×10 5 dynes/cm 2 .