Patent ID: 9550969
Date: 2017-01-24
CPC Classifications: B01F,C12M

Claim:
1. An inflatable bioreactor bag for cell cultivation comprising: a top sheet and a bottom sheet, each being formed of flexible material and joined together to form two end edges and two side edges; a plurality of tubular baffles, each tubular baffle being disposed within the inflatable bioreactor bag and mounted to the top sheet via a single inlet and outlet port corresponding to the tubular baffle for transporting material into and out of said inflatable bioreactor bag; and a plurality of diffusers mounted to the bottom sheet, each diffuser corresponding to each tubular baffle, and each diffuser is configured to mount each tubular baffle to the bottom sheet, wherein the tubular baffle extends in a direction away from the bottom sheet in a region where the shortest distance to the closest one of said two end edges is higher than about one fourth of the shortest distance between said two end edges, and wherein each diffuser comprising at least one opening forming an open flow-path for cell suspension through the diffuser and a lumen of the tubular baffle, wherein at least one baffle of the plurality of baffles is of a curved shape and in contact with the cell suspension within said inflatable bioreactor bag, and offset and spaced from the remaining of the plurality of the tubular baffles in the region.