Patent ID: 9702876
Date: 2017-07-11
CPC Classifications: G01N

Claim:
1. A method for predicting a risk of getting cancer in a female subject that does not suffer from cancer, wherein said cancer is breast cancer or lung cancer, said method comprising: measuring the level of Pro-Enkephalin or fragments thereof of at least 5 amino acids in a sample of serum or plasma obtained from said female subject using an immunoassay that has antibodies or fragments of antibodies that bind to Pro-Enkephalin or said fragments thereof; correlating said level of Pro-Enkephalin or fragments thereof with a risk of said subject for getting breast or lung cancer, wherein a reduced level is predictive for an enhanced risk of getting breast or lung cancer; and treating said subject with an anti-breast cancer or an anti-lung cancer treatment; a) bringing said serum or plasma sample into contact with a solid phase comprising a bound first antibody or first antibody fragment that binds to Pro-Enkephalin or fragments thereof whereby Pro-Enkephalin or said fragments thereof within said sample react with said bound first antibody or antibody fragment to form a complex bound to said solid phase, b) contacting said solid phase with the bound complex with a second antibody or second antibody fragment, wherein said second antibody or second antibody fragment is labelled with a detectable label, and whereby the labelled second antibody or second antibody fragment binds to said complex, and c) measuring the level of Pro-Enkephalin or fragments thereof in said sample by measuring the amount of labelled second antibody or second antibody fragment bound to the complex on said solid phase.