Patent ID: 9375410
Filing Date: 2016-06-28
CPC Classification: A61K,A61P,Y10T

Claim Text:
1. A method of relieving muscle spasms in a patient in need thereof, comprising administering a multi-particulate dosage form comprising a plurality of active-containing particles comprising about 30 mg of cyclobenzaprine or pharmaceutically acceptable salts thereof and a dissolution rate controlling polymer surrounding the cyclobenzaprine or pharmaceutically acceptable salts thereof; wherein said dissolution rate controlling polymer is selected from the group consisting of ethers of cellulose, esters of cellulose, cellulose acetate, ethyl cellulose, polyvinyl acetate, neutral copolymers based on ethylacrylate and methylmethacrylate, copolymers of acrylic and methacrylic acid esters with quaternary ammonium groups, pH-insensitive ammonio methacrylic acid copolymers, and mixtures thereof; wherein following a single oral administration of the multi-particulate dosage form, the dosage form provides a maximum blood plasma concentration (C wherein following a single oral administration of the multi-particulate dosage form, the dosage form provides a therapeutically effective plasma concentration over a period of 24 hours to treat muscle spasm associated with painful musculoskeletal conditions.