Patent ID: 9238005
Filing Date: 2016-01-19
CPC Classification: A61K,A61M,A61P

Claim Text:
1. A respirable dry powder comprising respirable dry particles that comprise a divalent metal cation salt, wherein the divalent metal cation salt provides divalent metal cation in an amount of about 3% to about 5% by weight of the dry particle, and the respirable dry particles that comprise a divalent metal cation salt have a volume median geometric diameter (VMGD) of about 5 microns or less, a tap density of greater than 0.4 g/cubic centimeter (cc) and are further characterized by a capsule emitted powder mass (CEPM) of at least 80% when emitted from a passive dry powder inhaler that has a resistance of about 0.036 sqrt(kPa)/liters per minute (LPM) under the following conditions: an inhalation energy of 1.15 Joules at a flow rate of 30 LPM using a size 3 capsule that contains a total mass of 25 mg, said total mass consisting of the respirable dry particles that comprise a divalent metal cation salt, and wherein the VMGD of the dry particles emitted from the inhaler is 5 microns or less.