Patent ID: 9488600
Filing Date: 2016-11-08
CPC Classification: C12Q,G01N,G01R

Claim Text:
1. A nanochannel sensor comprising: a first antenna structure providing an electrically conductive material defining a nanoscale through-channel; a membrane having a first side and a second side and supporting the first antenna structure so that the through-channel provides a passage through the membrane between the first side and second side; and a second antenna structure proximate to the first antenna structure to electrically couple radiofrequency signals between the first antenna structure and the conductive material of the second antenna structure; wherein the second antenna structure is configured to communicate with a measurement circuit producing a radiofrequency signal and measuring a change in the radiofrequency signal with the passage of a molecule through the nanoscale through-channel of the first antenna structure caused by a change in impedance of the electrically conductive material of the first antenna structure as coupled to the second antenna structure and the molecule; wherein the nanoscale through-channel further comprises a nanoscale pore formed by a biomolecule coated with metallic nanoparticles; and wherein the nanoscale pore has an internal diameter of less than three nanometers.