Patent ID: 9278929
Filing Date: 2016-03-08
CPC Classification: C07D

Claim Text:
1. A process of making 4-(phenylamino)-1-(phenylalkyl)-4-piperidinecarboxamide, by converting in sequence: a) 1 -phenylalkyl-4-piperidinone to 4-(phenylamino)-1-(phenylalkyl)-4-piperidinenitrile; and b) said 4-(phenylamino)-1-(phenylalkyl)-4-piperidinenitrile, to 4-(phenylamino)-1-(phenylalkyl)-4-piperidinecarboxamide, by reaction in trifluoroacetic acid solvent with non-aqueous sulfuric acid, said phenylalkyl being phenylmethyl or phenylethyl.