Patent ID: 9504405
Filing Date: 2016-11-29
CPC Classification: A61B,G01R,G06F,G16H

Claim Text:
1. A method, comprising: applying a magnetic field sufficient to distribute magnetic particles present in a body into a mask having a spatial arrangement in a lumen of subsurface vasculature; detecting a response signal transmitted from the subsurface vasculature, wherein the response signal includes a background signal and an analyte response signal indicative of interaction of functionalized particles present in the body with the one or more target analytes, wherein the spatial arrangement of the mask formed by the magnetic particles modulates the analyte response signal with respect to the background signal as the functionalized particles in the body flow past the spatial arrangement of the mask, such that a period of the unmodulated analyte response signal is different than a period of the modulated analyte response signal as detected, and such that the period of the modulated analyte response signal as detected is different than a period of the background signal as detected; and non-invasively detecting the one or more target analytes by differentiating the analyte response signal from the background signal due, at least in part, to the modulation of the analyte response signal.