Patent ID: 9279158
Filing Date: 2016-03-08
CPC Classification: A61P,C12Q

Claim Text:
1. A kit for practicing a method of determining response to therapy in a human subject having Inflammatory Bowel Disease (IBD) that includes measuring in a serum sample from the subject the level of at least one differentially expressed miRNA, wherein the differentially expressed miRNA comprises miR-484 having a serum miRNA significance threshold of p<0.05, said kit comprising an oligonucleotide that specifically hybridizes to at least one differentially expressed miRNA, said oligonucleotide being (i) immobilized on a solid support or (ii) detectably labeled, and one or more of a physiologically acceptable carrier, instructions for use, a container for serum, and an assay substrate; wherein said at least one differentially expressed miRNA comprises miR-484.