Patent ID: 9462970
Filing Date: 2016-10-11
CPC Classification: A61B

Claim Text:
1. A method of determining glucose level in a subject, comprising: inserting an in vivo sensor in subcutaneous tissue in contact with interstitial fluid of a subject; positioning an on-body unit on a surface of skin of the subject, wherein the on-body unit is in electrical contact with the in vivo sensor and in communication with a display; measuring glucose in the interstitial fluid of the subject with the in vivo glucose sensor to produce at least three uncompensated glucose measurements, wherein the three uncompensated glucose measurements including a first uncompensated glucose measurement at an initial reference time, a second uncompensated glucose measurement at a first prior reference time, and a third uncompensated glucose measurement at a second prior reference time; determining a first scaled rate-of-change by multiplying a first weighting coefficient on a first rate of change computed from the first uncompensated glucose measurement at the initial reference time relative to the second uncompensated glucose measurement at the first prior reference time; determining a second scaled rate-of-change by multiplying a second weighting coefficient on a second rate of change computed from the first uncompensated glucose measurement at the initial reference time relative to the second uncompensated glucose measurement at the second prior reference time; and calculating a lag-compensated glucose level from the uncompensated glucose measurements by adding the first scaled rate-of-change, the second scaled rate-of-change and the first uncompensated glucose measurement; and displaying the lag compensated glucose level to the subject on the display, wherein the lag-compensated glucose level correlates with the subject's blood glucose level at the initial reference time.