Patent ID: 9416170
Filing Date: 2016-08-16
CPC Classification: A61K,C07K,C12N,C40B,G01N

Claim Text:
1. A polypeptide comprising a human fibronectin type 3 tenth ( 10 Fn3) domain, which comprises AB, BC, CD, DE, EF, and FG loops and β-strands A, B, C, D, E, F, and G, wherein the 10 Fn3 domain comprises modifications only in the amino acid sequence of the FG loop relative to the FG loop of the wild-type human 10 Fn3 domain as set forth in SEQ ID NO: 6, and in the amino acid sequence of the CD loop relative to the corresponding loop of the wild-type human 10 Fn3 domain as set forth in SEQ ID NO: 6, wherein the modifications contribute to binding a target.