Patent ID: 9417249
Filing Date: 2016-08-16
CPC Classification: G01N

Claim Text:
1. A method for predicting the risk of pre-term birth in a pregnant subject, the method comprising: (a) providing a sample from the pregnant subject; (b) enriching the sample in (a) for exosomes; (c) detecting a level of transthyretin (TTR) in the sample of (b); (d) detecting a level of one or both of collagen type XXVII α1 (COL27A1) and growth arrest-specific protein 1 (GAS1) in the sample of (b); and (e) identifying a subject having an elevated level of two or more of TTR, COL27A1, and GAS1, compared to a threshold level(s) as having an increased risk of pre-term birth.