Patent ID: 9441034
Filing Date: 2016-09-13
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An isolated antibody that binds to the extracellular domain of PDGFRβ and neutralizes PDGFRβ activity, said antibody comprising a V L domain comprising CDRs LCDR1, LCDR2, and LCDR3 and a V H domain comprising CDRs HCDR1, HCDR2, and HCDR3, wherein LCDR1 has the amino acid sequence shown in SEQ ID NO:433; LCDR2 has the amino acid sequence shown in SEQ ID NO:434; LCDR3 has the amino acid sequence shown in SEQ ID NO:435; HCDR1 has the amino acid sequence shown in SEQ ID NO:436; HCDR2 has the amino acid sequence shown in SEQ ID NO:437; HCDR3 has an amino acid sequence selected from the group consisting of SEQ ID NOs:438-442.