Patent ID: 9278126
Filing Date: 2016-03-08
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method of raising an immune response in a human subject, the method comprising administering a vaccine to the human subject who is ≦5 years old and characterized in that the administration of the vaccine induces a protective immune response in the subject against at least one influenza B strain, wherein the vaccine comprises: (i) a concentration of hemagglutinin in the vaccine of at least 12 μg/mL per strain from at least two influenza A virus strains, a B/Victoria/2/87-like influenza B virus strain, and a B/Yamagata/16/88-like influenza B virus strain; and (ii) an oil-in-water emulsion adjuvant with submicron oil droplets, wherein the oil-in-water emulsion adjuvant comprises squalene and the squalene concentration in the vaccine is <19 mg/ml.