Patent ID: 9353371
Filing Date: 2016-05-31
CPC Classification: C07H,C12N

Claim Text:
1. A compound comprising a modified oligonucleotide consisting of 15 to 24 linked nucleosides and having a nucleobase sequence comprising a complementary region comprising at least 15 contiguous nucleobases complementary to a target region of equal length within exon 3 or intron 3 of an Usher transcript, wherein the Usher transcript has the nucleobase sequence of SEQ ID NO.: 1, and wherein the complementary region of the modified oligonucleotide is 100% complementary to the target region and comprises 10 contiguous nucleobases of SEQ ID NO: 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 24, 25, 26, 28, 29, 30, 31, 49, 50, 51, 52, 53, 54, 55, 56, 57, or 58.