Patent ID: 9446136
Filing Date: 2016-09-20
CPC Classification: A61K,A61L,A61P,C08B,C08J

Claim Text:
1. A method of treating a mammalian subject having osteoarthritis, comprising administering a therapeutically effective amount of a hydrogel composition into an intra-articular space of a joint of the subject, the hydrogel composition comprising crosslinked hydrogel particles comprising triamcinolone or a pharmaceutically acceptable salt thereof in an aqueous solution comprising hyaluronic acid, wherein the crosslinked hydrogel particles are formed by reaction of polyethylene glycol dithiol with 2-(vinylsulfonyl)ethoxy-derivatized hyaluronic acid having from 1-10% of its hydroxyl groups derivatized with 2-(vinylsulfonyl)ethoxy groups.