Patent ID: 9447126
Filing Date: 2016-09-20
CPC Classification: C07F

Claim Text:
1. A method of making the compound AR-67 comprising: forming AP4622-1  from propane-1,3-dithiol and 3-hydroxybenzaldehyde; adding a solution of TBSC1 to a solution of AP4622-1 and imidazole to form AP4622-2 adding n-BuLi to a solution of AP4622-2 to form a first mixture and adding TBSC1 to the mixture to form AP4622-3 adding a solution of AP4622-3 to a solution of NBS to form AP4622-4 adding tetrabutylammonium fluoride trihydrate to a solution of AP4622-4 to form AP4622-5 adding HNO adding tin powder to a mixture of AP4622-6 to form AP4622 and combining AP4622, s-Trione, in the presence of TsOH to form AR-67.