Patent ID: 9505844
Filing Date: 2016-11-29
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A nucleic acid encoding a heavy chain variable region or a light chain variable region of an anti-human-CC-motif-receptor-7 (anti-human-CCR7) antibody capable of specifically binding to an extracellular domain of human CCR7, the antibody being produced by a hybridoma FERM BP-11369, FERM BP-11404, FERM BP-11371, FERM BP-11372, FERM BP-11373, FERM BP-11374, FERM BP-11375, or FERM BP-11376, and wherein the antibody is capable of interfering with a CCR7-dependent intracellular signal transduction mechanism caused by CCR7 ligand stimulation, without relying on complement-dependent cell lysis action or antibody-dependent cell-mediated cytotoxicity.