Patent ID: 9400281
Filing Date: 2016-07-26
CPC Classification: A61K,A61P,C07C,G01N

Claim Text:
1. A method of screening a therapeutic agent for K-Ras mutant cancer, comprising: immobilizing the DNA binding fragment of human p53 on an ELISA plate; adding the human SNAIL middle region protein fragment having amino acids 91-112 to the plate comprising the immobilized DNA binding fragment of human p53 fragment; and detection the extent of binding of the human SNAIL middle region fragment to the immobilized DNA binding fragment of the human p53 fragment in the presence, as well as the absence of a candidate drug, wherein if the binding in the presence of the drug is determined to be lower, the drug is considered a candidate for the therapeutic agent for treatment of K-Ras mutant driven cancer.