Patent ID: 9486413
Filing Date: 2016-11-08
CPC Classification: A61J,A61K,A61P,B29B,B29C,B29K,B29L

Claim Text:
1. A cured shaped pharmaceutical tablet comprising: (1) at least a first compression shaped and then air cured matrix, wherein said curing is without compression, by heated air having a temperature of at least about 62° C. for a duration of at least about 5 minutes, said matrix comprising hydrocodone or a pharmaceutically acceptable salt thereof in combination with at least one high molecular weight polyethylene oxide having, based on rheological measurements, an approximate molecular weight selected from 4,000,000, 7,000,000, and a combination thereof, and optionally further comprising at least one low molecular weight polyethylene oxide having, based on rheological measurements, an approximate molecular weight of less than 1,000,000; (2) optionally a second air cured matrix comprising an hydrocodone or a pharmaceutically acceptable salt thereof in combination with at least one low molecular weight polyethylene oxide having, based on rheological measurements, an approximate molecular weight of less than 1,000,000; and (3) optionally a coating, wherein, in said tablet said high molecular weight polyethylene oxide is at least 54% by weight of the total weight of said uncoated tablet; said low molecular weight polyethylene oxide, if present, is at least 10% by weight of the total weight of said uncoated tablet; and said tablet provides a once-daily extended release of hydrocodone or pharmaceutically acceptable salt thereof from said tablet.