Patent ID: 9347088
Filing Date: 2016-05-24
CPC Classification: C12Q

Claim Text:
1. A method, comprising: assaying by real-time RT-PCR the expression of each gene in a set of genes in a biological sample wherein said set of genes comprises from 10 to 16 genes or consists of 10 to 16 genes, said 10 to 16 genes being selected from the group consisting of the alpha-fetoprotein (AFP), aldehyde dehydrogenase 2 (ALDH2), amyloid P component serum (APCS), apolipoprotein C-IV (APOC4), aquaporin 9 (AQP9), budding uninhibited by benzimidazoles 1 (BUB1), complement component 1 (CIS), cytochrome p450 2E1 (CYP2E1), discs large homolog 7 (DLG7), dual specificity phosphatase 9 (DUSP9), E2F5 transcription factor (E2F5), growth hormone receptor (GHR), 4-hydroxyphenylpyruvase dioxygenase (DHP), immunoglobulin superfamily member 1 (IGSF1), Notchless homolog 1 (NLE1) and the ribosomal protein L10a (RPL10A) genes, wherein the biological sample is a hepatoblastoma (HB) or a hepatocellular carcinoma (HCC) obtained from a patient after surgical resection or orthotopic liver transplantation (OLT).