Patent ID: 9435490
Filing Date: 2016-09-06
CPC Classification: B01L,F16K,F17D,Y10T

Claim Text:
1. A microfluidic device comprising: a thermoplastic elastomer (TPE) film having first and second opposite surfaces; a substrate forming a seal with the first surface around a periphery of a channel defined between the substrate and TPE film; and a part of the TPE film defining a membrane having a first side defining part of the channel, and a second side mechanically actuable to close the channel, wherein compositions of the TPE film and the substrate are chosen so that their respective Hildebrandt parameters differ by less than 10 (J/cm 3 ) 1/2 to permit the membrane to be contact bonded to a channel wall if subjected to a first temperature and pressure regime, to semipermanently retain the channel closed under no persistent force on the second side of the membrane, until re-opened by heating or a thermomechanical stimulus without any layer of adhesive between the TPE film and substrate.