Patent ID: 9290538
Filing Date: 2016-03-22
CPC Classification: A61K,A61P,C07K,C12N

Claim Text:
1. A chimeric peptide consisting of a first domain and a second domain directly linked by a covalent bond or linked by a linker sequence of 1 to 10 amino acids, the first domain comprising a trafficking sequence, and the second domain consisting of a c-Jun N-terminal kinase (JNK) inhibitor sequence of SEQ ID NO: 2 or a variant sequence of SEQ ID NO: 2 with 1 or 2 amino acids deleted from either terminus of SEQ ID NO: 2, wherein the trafficking sequence comprises the amino acid sequence of SEQ ID No: 5, 6, 7 or 8 or a sequence variant of SEQ ID NO: 5 or 6 with 1 or 2 amino acids deleted from either terminus of SEQ ID NO: 5 or 6, and wherein the trafficking sequence and the JNK inhibitor sequence are composed exclusively of D-enantiomeric amino acids.