Patent ID: 9446123
Filing Date: 2016-09-20
CPC Classification: A61K,A61P,C07K,C12N,C12Y

Claim Text:
1. A multimeric complex comprising: a) a first fusion protein comprising (i) a first IgG antibody and (ii) an AD (anchoring domain) moiety from an AKAP protein attached to the C-terminal end of each light chain of the antibody; and b) a second fusion protein comprising (iii) a Fab fragment of a second antibody, and (iv) a DDD (dimerization and docking domain) moiety, wherein the amino acid sequence of the DDD moiety is residues 1-44 of human protein kinase A (PKA) regulatory subunit RIIα; wherein two copies of the DDD moiety form a dimer that binds to one copy of the AD moiety to form the complex.