Patent ID: 9382583
Filing Date: 2016-07-05
CPC Classification: B01L,B82Y,C12Q

Claim Text:
1. A method for the amplification of nucleic acids comprising amplifying the nucleic acids, wherein the amplification comprises one or more heating steps, and a step of providing nanoparticles with the nucleic acids in a reaction volume, wherein the heating in at least one heating step is achieved at least partially through excitation of the nanoparticles so that the nanoparticles transfer heat to their environment through the excitation, wherein through the excitation of the nanoparticles, the environment of the nanoparticles is heated locally, wherein the interval of the excitation is chosen to be shorter or equal to a critical excitation time t1=(s1*|x|) 2 /D, and wherein s1=100, |x| is the mean nanoparticle distance, and D is the thermal diffusivity of the medium between the nanoparticles.