Patent ID: 9383360
Filing Date: 2016-07-05
CPC Classification: C07K,G01N,Y02A

Claim Text:
1. A method of aiding in the diagnosis of Lyme disease, comprising: assaying a first sample obtained from a subject having, or suspected of having, Lyme disease for one or more peptides selected from the group consisting of: peptides of SEQ ID NOs: 56, 59, 60, 61, 62, 63, 64, 66 and the product of cleavage at cleavage sites 108 and 124, produced by proteolytic activity of Borrelia burgdorferi sensu lato HtrA on at least one host protein substrate, to produce an assay result wherein detection of the one or more peptides is indicative of an active Borrelia burgdorferi sensu lato infection in the subject.