Patent ID: 9234203
Filing Date: 2016-01-12
CPC Classification: C07C,C08G,C12N,C12P,C12Y

Claim Text:
1. A stabilized recombinant expression plasmid vector comprising: a polynucleotide encoding a polypeptide that counteracts a toxin polypeptide toxic to a host cell, the toxin polypeptide being encoded by aat or abt gene, or mutants thereof, such that the toxin polypeptide has substantially the same function as the polypeptide encoded by aat or abt gene, in the host cell, a polynucleotide encoding the toxin polypeptide, and a polynucleotide encoding a polypeptide expression product, wherein: the stabilized recombinant expression plasmid vector is derived from a the toxin gene and the antitoxin gene comprise a gene pair selected from the group consisting of aat/aai gene pair, abt/abi gene pair, and encoding functional fragments thereof.