Patent ID: 9265722
Filing Date: 2016-02-23
CPC Classification: A61K,A61P

Claim Text:
1. A solid form botulinum toxin oral formulation for the treatment of a gastrointestinal disorder in a human patient, comprising: an effective amount of a botulinum toxin type A, encapsulated in a carrier, thereby forming a botulinum toxin oral formulation, wherein the carrier is formulated to release the botulinum toxin type A in a gastrointestinal tract of the human patient without a significant immune system response, wherein a controlled gastric retention of the solid form can be achieved by a method selected from the group consisting of mucoadhesion, flotation, sedimentation, expansion, or by a simultaneous administration of pharmacological agents which delay gastric emptying, and wherein the effective amount of the botulinum toxin type a is determined relative to the patient's weight and ranging between 0.01 units/kg and about 25 units/kg.