Patent ID: 9486400
Filing Date: 2016-11-08
CPC Classification: A61K,A61Q

Claim Text:
1. A method of improving the appearance of aging skin comprising: a. identifying a target portion of skin that exhibits a sign of aging skin; and b. applying a composition comprising about 0.001% to about 5% of artichoke leaf extract and about 0.001% to about 5% of carob fruit extract in combination to the target portion of skin for a period of time sufficient for the artichoke leaf extract and carob fruit extract to improve the appearance of aging skin wherein the artichoke leaf extract and carob fruit extract in combination provide a synergistic increase in the up-regulation of at least one epidermal-associated gene selected from the group consisting of KRT2, KRT6A, CLDN1, LOR, FLG, IVL, KRT10, AQP3, and KRT14.