Patent ID: 9486446
Filing Date: 2016-11-08
CPC Classification: A61K,A61P

Claim Text:
1. An orally-disintegrating solid preparation, comprising: (1) fine granules A that release a pharmaceutically active ingredient in a manner of controlled release, wherein the outermost layer of each of the fine granules A is further coated with a coating layer comprising hydroxypropylmethylcellulose and low-substituted hydroxypropylcellulose, a weight ratio of the hydroxypropylmethylcellulose relative to the low-substituted hydroxypropylcellulose in the coating layer on the outermost layer of the fine granules is 1:10-10:1, and the coating layer suppresses breakage of the fine granules A during tableting; and (2) fine granules B that have a different release rate of a pharmaceutically active ingredient from that of the fine granules A of (1).