Patent ID: 9434688
Filing Date: 2016-09-06
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A method of inhibiting an androgen receptor, in a subject in need thereof comprising administering to the subject a therapeutically effective amount of the compound of formula (III) wherein  is a six membered heteroaryl ring structure containing one to two nitrogen atoms; Y is NR R R a is an integer from 0 to 4; R wherein each R wherein the aryl is optionally substituted with one or more substituents independently selected from halogen, hydroxy, carboxy, lower alkyl, halogen substituted lower alkyl, lower alkoxy, halogen substituted lower alkoxy, cyano, nitro, amino, lower alkylamino or di(lower alkyl)amino; b is an integer from 0 to 1; c is an integer from 0 to 1; R R R wherein each Z is independently selected from the group consisting of —S(O) wherein each R wherein the cycloalkyl, aryl or heteroaryl group, whether alone or part of a substituent group is optionally substituted with one or more substituents independently selected from halogen, hydroxy, carboxy, lower alkyl, halogen substituted lower alkyl, lower alkoxy, cyano, nitro, amino, lower alkylamino, di(lower alkyl)amino, —S(O) provided that when Z is O, NH or N(lower alkyl) then Z is other than lower alkenyl; or a pharmaceutically acceptable salt thereof.