Patent ID: 9417248
Filing Date: 2016-08-16
CPC Classification: C07K,G01N

Claim Text:
1. A compound comprising: a. a first epitope comprising the amino acid sequence ACNFNDVTTRLRENELTYYCAAK (SEQ ID NO: 11); b. a second epitope comprising the sequence R c. an optional label, wherein said label is fluoroescent, phosphorescent, chemiluminescent, chromogenic, affinity-based, enzyme based, or radioactive; and d. a linker that joins the first epitope to the second epitope, wherein the linker is selected from the group consisting of an aliphatic moiety, a heteroaliphatic moiety, an acyl, and an aryl, wherein: wherein each substituent is independently selected from the group consisting of a branched alkyl, an unbranched alkyl, a branched alkenyl, an unbranched alkenyl, a branched alkynyl, an unbranched alkynyl, heterocyclic, —OR A ; —C(═O)R A ; —CO 2 R A ; —SR A ; —SOR A ; —SO 2 R A ; ═O; ═N(R A ); ═S; —N(R A ) 2 ; —NHC(═O)R A ; —NR A C(═O)N(R A ) 2 ; —OC(═O)OR A ; —OC(═O)R A ; —OC(═O)N(R A ) 2 ; and NR A C(═O)OR A ; wherein each occurrence of R A is independently a hydrogen, an aliphatic moiety, a heteroaliphatic moiety, an acyl moiety; an aryl moiety; a heteroaryl moiety; an alkoxy moiety; an aryloxy moiety; an alkylthio moiety; an arylthio moiety; an amino moiety; an alkylamino moiety; a dialkylamino moiety; a heteroaryloxy moiety; or a heteroarylthio moiety; with the proviso that the linker is not a peptide bond.