Patent ID: 9417244
Filing Date: 2016-08-16
CPC Classification: G01N

Claim Text:
1. A method of diagnosing cancer in a subject, the method comprising: providing a sample comprising blood from the subject; and separating cells that express a cancer cell surface marker from the sample by contacting the sample with a device for separation of the cells in a sample, the device comprising an inlet, and outlet, and one or more surfaces coated with antibodies or antigen-binding fragments thereof that bind to each of cancer cell surface markers cadherin 1 (CDH1), CDH2, CDH3, CDH4, CDH5, CDH9, CDH11, CDH17, CDH19, protocadherin 9 (PCDH9) and PCDH beta 13 (PCDHb13), under conditions sufficient to allow binding of the antibodies or antigen-binding fragments thereof to cells expressing the surface marker; detecting the presence of separated cells that express a cancer cell surface marker on a cell in the sample; and identifying the subject as having cancer based on the presence of a cell that expresses a cancer cell surface marker in the sample.