Patent ID: 9442085
Filing Date: 2016-09-13
CPC Classification: A61B,G01N

Claim Text:
1. A method to quantify biomarkers, comprising providing a sample comprising a biomarker, the biomarker comprising one or more chemicals that are related to a physiological condition; fractionating the sample to provide sample fractions; using an X-ray fluorescence spectrometer comprising an X-ray excitation source to perform an X-ray fluorescence analysis on a sample fraction to obtain spectral features derived from the biomarker; and quantifying the X-ray fluorescence signal of the biomarker; wherein the X-ray fluorescence spectrometer irradiates the sample fraction with polychromatic X-rays, and the X-ray fluorescence analysis comprises multiple X-ray fluorescence analyses obtained wherein the sample fraction is disposed at two or more different angles relative to the excitation source.