Patent ID: 9376351
Filing Date: 2016-06-28
CPC Classification: A23L,A23V,A61K,B01D,C07B,C07C

Claim Text:
1. A process to produce water soluble and oil soluble plant extract fractions comprising, respectively, rosmarinic acid and carnosic acid from Labiatae herbs comprising the following steps: a) contacting the Labiatae herbs with a solvent comprising about 50%-90% ethanol for at least 30 minutes; b) filtering to obtain a solution comprising both oil soluble and water soluble plant extract fractions; c) removing 50%-97% of the solvent from the solution of step b) under vacuum until ethanol levels drop to about 0%-35% and monitoring pH; d) discontinuing solvent removal when the pH has been determined to be of a value in a range of about 3-5, and filtering to obtain a solid fraction comprising carnosic acid and carnosol and a liquid fraction; e) isolating the solid fraction comprising carnosic acid and carnosol obtained in step d), and optionally, further purifying the solid fraction comprising carnosic acid and carnosol; and f) removing residual water and ethanol from the liquid fraction obtained in step d) to provide a second solid fraction comprising rosmarinic acid, and optionally, further purifying the second solid fraction comprising rosmarinic acid.