Patent ID: 9518982
Filing Date: 2016-12-13
CPC Classification: C12Q,G01N,Y10T

Claim Text:
1. A kit for detection of multiple targets in a biological sample, comprising: multiple probes, wherein each probe comprises a binder and a fluorophore, wherein each probe is configured to specifically bind to a target via the binder, wherein the binder comprises a primary antibody and wherein the fluorophore is coupled to a secondary antibody that binds to the target via the primary antibody; and at least one chemical agent in a concentration that, when applied to each probe, is configured to modify the fluorescence signal provided by the fluorophore of at least one probe without affecting the integrity of the binder in the at least one probe such that the primary antibody, when bound to the target, remains bound to the target after modification of the fluorescent signal by the at least one chemical agent under conditions in which the fluorophore is destroyed.