Patent ID: 9468684
Filing Date: 2016-10-18
CPC Classification: A61K,A61L,A61P

Claim Text:
1. A hydrogel composition comprising: a first hydrogel comprising a first reactive precursor comprising a multi-arm polyether possessing electrophilic groups, a second reactive precursor comprising nucleophilic groups, and at least one bioactive agent; and a barrier layer on an external surface of the first hydrogel, the barrier layer comprising at least one initiated precursor selected from the group consisting of phosphorylcholine containing monomers, furanone functional vinyl monomers, N-vinyl pyrrolidone, siloxane functional vinyl compounds, polyethylene glycol-silicone co-monomers having vinyl groups, pyrrole, liquid crystalline vinyl monomers, liquid crystalline vinyl polymers, and combinations thereof, wherein the barrier layer directs delivery of the bioactive agent from the first hydrogel in a direction opposite the barrier layer.