Patent ID: 9440927
Filing Date: 2016-09-13
CPC Classification: C07C,C07D

Claim Text:
1. A process for the preparation of a substituted 3′-hydrazino-biphenyl-3-carboxylic acid compound of formula I and salts thereof, wherein R represents hydrogen, linear or branched C 1-6 alkyl, C 3-8 cycloalkyl, optionally substituted benzyl, linear or branched alkylalkoxy, tetrahydrofuranyl, tetrahydropyranyl, medryloxybenzyl, trialkylsilyl, acyl, or trityl; the process comprising: a) reacting a compound of formula III, wherein R is as defined above, X is selected from the group consisting of Cl Br, and I, with a compound of formula IV, wherein R′ represents boronic acid, boronic acid ester or halogen in the presence of a metal catalyst; and (b) optionally, deprotecting the compound of formula I.