Patent ID: 9408802
Filing Date: 2016-08-09
CPC Classification: A61K

Claim Text:
1. A transdermal formulation comprising: an active pharmaceutical ingredient, wherein said active pharmaceutical ingredient is clonidine; a polyisobutylene pressure sensitive adhesive, wherein said polyisobutylene pressure sensitive adhesive is present in an amount ranging from about 50-99.6% w/w; a binder, wherein said binder is cross-linked polyvinylpyrrolidone; a filler, wherein said filler comprises silicon dioxide, wherein the silicon dioxide is present in an amount ranging from about 2-5% w/w, further wherein the ratio of the silicon dioxide to cross-linked polyvinylpyrrolidone ranges from about 1:1 to about 1:5; and mineral oil; wherein said formulation is a component of a transdermal delivery system that delivers said active pharmaceutical ingredient for up to seven days, wherein delivery of the active pharmaceutical ingredient increases over the seven days.