Patent ID: 9403757
Filing Date: 2016-08-02
CPC Classification: A61K,C07C

Claim Text:
1. A process for preparation of an N-acylated monomeric compound selected from 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (Compound A) and N,N′-bis(2,3-dihydroxypropyl)-5-formamido-2,4,6-triiodoisophthalamide (Compound C) comprising a step wherein Compound B2, wherein each X individually denotes a hydrogen or an acyl group, provided that at least one of the X-groups attached to the nitrogen is an acyl group; is subjected to deacylation of the acylated hydroxyl groups by adding the Compound B2 to an aqueous solution of a deacylating agent.