Patent ID: 9234182
Filing Date: 2016-01-12
CPC Classification: A61K,A61P,C12N

Claim Text:
1. An attenuated recombinant parvovirus comprising a DNA sequence obtained from an attenuated first parvovirus; wherein the DNA sequence encoding the capsid protein or fragment thereof of said first parvovirus is replaced by a DNA sequence encoding a capsid protein or fragment thereof derived from a second parvovirus; wherein said first parvovirus is a type 2 canine parvovirus; wherein said second parvovirus is a type 2c canine parvovirus; wherein the attenuated recombinant canine parvovirus comprises the DNA sequence encoding the capsid protein of a canine parvovirus type 2c isolate within the DNA sequence of an attenuated canine parvovirus type 2 virus; and wherein said fragment thereof of said second parvovirus comprises at least one amino acid difference from said fragment thereof of said first parvovirus.