Patent ID: 9415020
Filing Date: 2016-08-16
CPC Classification: A61K,A61P,Y10S

Claim Text:
1. A hypotonic formulation comprising mucus penetrating particles, the particles comprising; a mucus penetration enhancing polyalkylene oxide coating which enhances diffusion of the particles through mucus, the coating having a density of polyalkylene oxide equivalent to at least about five 5 kD polyethylene glycol/100 nm a therapeutic, prophylactic, diagnostic or nutraceutical agent for administration to a mucosal tissue, in an excipient which is hypotonic for epithelium selected from the group consisting of the eye, gastrointestinal tract, and vagina, the excipient causing water uptake by the epithelium, resulting in the rapid transport of the mucus penetrating particles to the epithelial surface.