Patent ID: 9511022
Filing Date: 2016-12-06
CPC Classification: A61K,A61P

Claim Text:
1. A method for reducing active ingredient particles from agglomerating in a suspension; the suspension containing an active ingredient and at least one of silicone oil and silicone oil derivative in a dispersion medium; the active ingredient being at least one member selected from the group consisting of aripiprazole and a compound of formula (II): the active ingredient being in a form of particles having a mean primary particle size of 0.1 μm or larger and smaller than 200 μm; the method comprising mixing the active ingredient with the at least one of silicone oil and silicone oil derivative in a dispersion medium, in such a manner that the at least one of silicone oil and silicone oil derivative is contained in an amount of 0.001 to 0.2 weight parts relative to 100 weight parts of the active ingredient contained in the suspension.