Patent ID: 9249223
Filing Date: 2016-02-02
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A humanized antibody capable of binding specifically to CXCR4, or a CXCR4-binding fragment of same, wherein said humanized antibody, or CXCR4-binding fragment of same, comprises: heavy and light chains, said heavy chain having complementarity-determining regions (CDRs) consisting of CDR-H1, CDR-H2 and CDR-H3, and the said light chain having CDRs consisting of CDR-L1, CDR-L2 and CDR-L3, wherein said CDR-H1, CDR-H2 and CDR-H3 comprise respectively the sequences of SEQ ID Nos. 4, 5 and 6, and said CDR-L1, CDR-L2 and CDR-L3 comprise respectively the sequences of SEQ ID Nos. 7, 8 and 9; and said heavy chain having a variable region of sequence selected from SEQ ID Nos. 85 and 87 and said light chain having a variable region of sequence selected from SEQ ID Nos. 86 and 88.