Patent ID: 9376427
Filing Date: 2016-06-28
CPC Classification: A61P,C07D

Claim Text:
1. A one-pot process for preparing rivaroxaban, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide, of formula I: or a stereochemically isomeric form or a racemic mixture thereof, comprising: a) reacting 5-chlorothiophene-2-carboxylic acid of formula IV: b) reacting the sulfonyl ester compound of formula III with 4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one of formula II: