Patent ID: 9309220
Filing Date: 2016-04-12
CPC Classification: A61P,C07D

Claim Text:
1. A process for preparing an enantiomerically enriched or enantiomerically pure compound of Formula (I): or a pharmaceutically acceptable form thereof, comprising (step_1.1) transforming an enantiomerically enriched or enantiomerically pure compound of Formula (II): or a salt thereof, wherein to an enantiomerically enriched or enantiomerically pure compound of Formula (III), or a salt thereof: wherein under conditions suitable for ester to acid transformation, wherein step 1.1 occurs in the presence of an acid; (step 1.2) cyclizing the enantiomerically enriched or enantiomerically pure compound of Formula (III) to an enantiomerically enriched or enantiomerically pure compound of Formula (I-a): under conditions suitable for cyclization; (step 1.3) where Y is an amino protecting group, deprotecting the enantiomerically enriched or enantiomerically pure compound of Formula (I-a) to an enantiomerically enriched or enantiomerically pure compound of Formula (I) under conditions suitable for deprotection; and (step 1.4) optionally transforming the enantiomerically enriched or enantiomerically pure compound of Formula (I) to a pharmaceutically acceptable salt thereof under conditions suitable for salt formation.