Patent ID: 9364470
Filing Date: 2016-06-14
CPC Classification: A61K,A61P

Claim Text:
1. A method of treating a subject suffering from hyperlipidemia or hypercholesterolemia, the method comprising administering to the subject an effective amount of an MTP inhibitor, wherein said administration comprises at least three step-wise, increasing dose levels of the MTP inhibitor, wherein a first dose level is from about 0.02 to about 0.059 mg/kg/day, a second dose level is from about 0.06 to about 0.19 mg/kg/day, and a third dose level is from about 0.2 to about 0.59 mg/kg/day; and wherein the MTP inhibitor is represented by: or a pharmaceutically acceptable salt thereof or the piperidine N-oxide thereof, and wherein the first dose level is administered for about two weeks, and wherein the second and third dose levels are each administered for about 4 weeks.