Patent ID: 9233318
Filing Date: 2016-01-12
CPC Classification: B01D,C07K

Claim Text:
1. A purification process for the compound of Formula 1, wherein said process comprising: (1) loading a crude compound 1 onto a macroporous adsorption resin; (2) washing the macroporous adsorption resin with an aqueous solution, an organic solvent or a mixed solution of an organic solvent and water; (3) eluting with an aqueous solution, an organic solvent or a mixed solution of an organic solvent and water to give a purified compound of Formula 1; wherein the macroporous adsorption resin is selected from a non-polar aromatic adsorption resin polymerized from styrene and divinylbenzene, or a moderately polar methacrylic adsorption resin comprising methacrylate unit in its structure; the organic solvent is selected from methanol, ethanol, or C the concentration gradient of the organic solvent is 10%-60% (v/v), and the pH of the aqueous solution, the organic solvent or the Mixed solution of an organic solvent and water is ≧7.