Patent ID: 9381243
Filing Date: 2016-07-05
CPC Classification: A61K,A61P

Claim Text:
1. A method of treating or reducing risk of systemic inflammation and/or severe infection, in a patient suffering from systemic inflammation and/or severe infection characterized by purpura fulminans; comprising administering to a patient in need thereof a combination of (1) one or more compounds selected from the group consisting of platelet inhibitors, wherein the platelet inhibitor is capable of inhibiting the GPIIb/IIIa receptor and (2) one or more compounds capable of modulating/preserving the endothelial integrity wherein the compound capable of modulating/preserving the endothelial integrity is selected from the group consisting of PGI2, PGX, and prostacyclin or a variant thereof, thereby treating or preventing organ failure in said patient.