Patent ID: 9383299
Filing Date: 2016-07-05
CPC Classification: B01D,B01J,B82Y,G01N,Y10T

Claim Text:
1. A method of capturing analytes in a bodily fluid, comprising: mixing a solution containing open-meshwork hydrogel capture particles that contain an analyte binding affinity molecule with a fluid solution that contains an analyte of interest; further comprising the analyte binding affinity molecule capturing the analyte of interest against a concentration gradient resulting in a higher analyte of interest concentration within the volume of the open-meshwork hydrogel capture particles; and further comprising eluting the analyte of interest, once captured, by a chemical treatment that dissociates the analyte of interest from the analyte binding affinity molecule within the volume of the open-meshwork hydrogel particles such that the pore size of the open-meshwork hydrogel capture particles does not change.