Patent ID: 9421228
Filing Date: 2016-08-23
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method of treating a disease selected from the group consisting of a malignant disease, a disease associated with transplantation of a graft and an autoimmune disease, in a subject in need thereof, the method comprising: (a) transplanting immature hematopoietic cells to the subject; and (b) administering to the subject a therapeutically effective amount of an isolated population of cells comprising non-graft versus host (GVHD) inducing anti-third party cells having a central memory T-lymphocyte (Tcm) phenotype, said cells being tolerance-inducing cells and capable of homing to the lymph nodes following transplantation, wherein when said immature hematopoietic cells are syngeneic with the subject, said isolated population of cells are selected syngeneic with the subject or non-syngeneic with the subject.