Patent ID: 9376677
Filing Date: 2016-06-28
CPC Classification: B01J,B82Y,C12N,C12Q,G01N

Claim Text:
1. A method of producing a molecular array comprising: (i) preselecting a plurality of oligonucleotides to be immobilised; (ii) labeling at least a portion of the plurality of oligonucleotides with one or more labels, thereby producing labeled oligonucleotides; (iii) immobilising at least a portion of the labeled oligonucleotides on a solid support at a density to allow each of said at least a portion of the labeled oligonucleotides on the solid support to be individually resolved, thereby forming two or more separate and discrete elements, at least two elements of said two or more elements being spatially addressable, each of said at least two elements comprising a plurality of labeled immobilised oligonucleotides from said at least a portion of the labeled oligonucleotides, wherein sequence identities of said at least a portion of the plurality of labeled immobilised oligonucleotides in each of said at least two elements is specified by a location of each of said at least two elements in which the oligonucleotides are contained; and (iv) analysing whether at least a portion of the labeled immobilised oligonucleotides of said at least two elements is individually optically resolvable from another portion of the labeled immobilised oligonucleotides, whereby said at least a portion of the labeled immobilised oligonucleotides on each of said at least two elements is individually optically resolvable from the another portion of the labeled immobilised oligonucleotides.