Patent ID: 9291568
Filing Date: 2016-03-22
CPC Classification: B01L,B82Y,C12Q,G01N,G02B,Y10T

Claim Text:
1. A nucleic acid sequencing instrument comprising: a removable sequencing chip having at least 10,000 analytical devices, each analytical device having a reaction cell, optical elements, and detection elements that detect light emitted from the reaction cell and convert the detected light into electrical data signals, wherein the reaction cell, the optical elements and the detection elements are pre-aligned and locked in during manufacturing of the removable sequencing chip and there is no substantial open or free space between the reaction cell, optical elements, and detection elements; the sequencing chip comprising integrated waveguides that deliver illumination light to the reaction cells; the sequencing chip having electrical connections that transfer the electrical data signals from the sequencing chip; a fluidic sample delivery device that delivers reagents for sequencing a sample on the sequencing chip; an illumination source that provides illumination to the integrated waveguides on the sequencing chip; a camera board in contact with the electrical connections on the sequencing chip, the camera board comprising circuitry for processing electrical data signals from the sequencing chip; and a computer in electrical communication with the camera board that receives processed data from the camera board.