Patent ID: 9278998
Filing Date: 2016-03-08
CPC Classification: A61P,C07K,C12N,G01N

Claim Text:
1. An H1 HA influenza hemagglutinin (“HA”) polypeptide variant whose amino acid sequence: i) shows at least 90% identity with a reference wild type H1 HA polypeptide that is the HA from A/California/04/2009 strain (SEQ ID NO: 46); ii) includes a sequence substitution relative to the reference at each of the following positions: and iii) differs from that of each of ADA76, A/duck/Alberta/35/76 (H1N1) (SEQ ID NO: 23); ASI30, A/Swine/Iowa/30 (H1N1) (SEQ ID NO: 24); APR34, A/Puerto Rico/8/34 (H1N1) (SEQ ID NO: 25); ASC18, A/South Carolina/1/18 (H1N1) (SEQ ID NO: 26); AT91, A/Texas/36/91 (H1N1) (SEQ ID NO: 27); ANY18, A/New York/1/18 (H1N1) (SEQ ID NO: 28); ADU63, A/Duck/Ukraine/1/63 (H3N8) (SEQ ID NO: 29); AAI68, A/Aichi/2/68 (H3N2) (SEQ ID NO: 30); AM99, A/Moscow/10/99 (H3N2) (SEQ ID NO: 31); ADS97, A/Duck/Singapore/3/97 (H5N3) (SEQ ID NO: 32); Viet04, A/Vietnam/1203/2004 (H5N1) (SEQ ID NO: 33).