Patent ID: 9492529
Filing Date: 2016-11-15
CPC Classification: A61K,A61P,C12N

Claim Text:
1. An in vitro method for priming of antigen specific CD4+ and/or CD8+ T cells for administration to a patient having a viral infection, said method comprising co-culturing (1) target T cells from the patient to be treated, (2) mature monocyte-derived dendritic cells from a first healthy donor, (3) virus material or virus associated proteins or peptides, and (4) lymphocytes from a second healthy donor sensitized against MHC class I and/or MHC class II antigens on antigen presenting cells (APCs) from the first healthy donor that are allogeneic with respect to the lymphocytes, wherein the lymphocytes are obtained by culturing non-proliferating peripheral blood mononuclear cells (PBMCs) from the first healthy donor with PBMCs from the second healthy donor.