Patent ID: 9428589
Filing Date: 2016-08-30
CPC Classification: A61K,A61P,C07K,C12N,C12Y

Claim Text:
1. A method comprising the step of contacting a compound of Formula I or a compound of Formula II with a first protein and a second protein under conditions suitable for cross-linking the first protein to the second protein, thereby cross-linking the first protein to the second protein, wherein the first protein comprises a first cysteine residue; the second protein comprises a second cysteine residue; the compound of Formula I is wherein Y is S, S═O, or S(═O) n is 0, 1, 2, 3, or 4; and R is independently selected from the group consisting of —H, —OH, —NH R′ is alkyl or aryl; and the compound of Formula II is wherein R″ is —H, alkyl, or aryl, or both R″, taken together, form a ring; wherein any alkyl, aryl, or ring may be substituted with —OH, alkyl, or halo.