Patent ID: 9255146
Filing Date: 2016-02-09
CPC Classification: A61K,A61P,C07H,C07K,Y02A

Claim Text:
1. An isolated nucleic acid encoding a monoclonal neutralizing antibody, or antigen-binding fragment thereof, that specifically interacts with at least one epitope of a Nogo-66 receptor, wherein the antibody, or antigen-binding fragment thereof, comprises: a VH domain comprising a sequence having at least 90% amino acid sequence identity with SEQ ID NO:3, and a VL domain comprising a sequence having at least 90% amino acid sequence identity with SEQ ID NO:4; or a VH domain comprising a sequence having at least 90% amino acid sequence identity with SEQ ID NO:5, and a VL domain comprising a sequence having at least 90% amino acid sequence identity with SEQ ID NO:6.