Patent ID: 9458233
Filing Date: 2016-10-04
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An antibody or an antigen-binding fragment thereof comprising: (i) a heavy chain CDR3 sequence as set forth in SEQ ID NO: 6, a light chain CDR3 sequence as set forth in SEQ ID NO: 8, a heavy chain CDR2 sequence according to SEQ ID NO: 10, and a light chain CDR2 sequence according to SEQ ID NO: 12; or (ii) a heavy chain CDR3 sequence as set forth in SEQ ID NO: 7, a light chain CDR3 sequence as set forth in SEQ ID NO: 9, a heavy chain CDR2 sequence according to SEQ ID NO: 11, and a light chain CDR2 sequence according to SEQ ID NO: 13; wherein said antibody or said antigen-binding fragment thereof specifically binds to human C5a; and wherein said antibody or said antigen-binding fragment thereof has a binding constant to human C5a with a Kd value of 100 nM or less.