Patent ID: 9457183
Filing Date: 2016-10-04
CPC Classification: A61K,A61M,A61N,C12M,C12N

Claim Text:
1. An apparatus for intracellular delivery of a delivered agent comprising: a hub comprising at least one electrical connector; a plurality of needles connected to the hub, wherein each needle of the plurality of needles comprises: an electrode; and an electrical power supply configured to generate an electric field at the electrode, wherein the electrical power supply is connected to the electrode through the at least one electrical connector, wherein the plurality of needles is arranged in an array of four needles arranged in a Y-type pattern comprising a center needle and three outer needles disposed around the center needle, wherein the center needle is a needle-electrode configured to apply a first polarity voltage, and the three outer needles are needle-electrodes, configured to apply a second polarity voltage; and wherein the center needle comprises apertures along the needle barrel, which are configured to direct delivery of the delivered agent toward apertures that are present on each of the three outer needles and each of the three outer needles comprises apertures along the needle barrel, which are configured to direct delivery of a delivered agent toward apertures that are present on the center needle so as to generate an opposing direction of delivery of the delivered agent.