Patent ID: 9423405
Filing Date: 2016-08-23
CPC Classification: G01N,H01J,Y10T

Claim Text:
1. A method of determining and displaying a human subject's risk of having cardiovascular disease, comprising: (a) generating a plasma and/or serum sample from a blood sample from a human subject, (b) purifying said plasma and/or serum sample using HPLC or gas chromatography (GC) to generate an HPLC or GC purified sample, (c) introducing at least a portion of said HPLC or GC purified sample into an analytical device, wherein said analytical device comprises an NMR spectrometer, a UV/Vis spectrometer, or a mass spectrometer; (d) activating said analytical device such that said at least a portion of said HPLC or GC purified sample is subjected to nuclear magnetic resonance analysis, UV/Vis spectrometry, or mass spectrometry analysis thereby determining a level of trimethylamine-N-oxide (TMANO) in said plasma or serum sample; and (c) graphically displaying said subject's risk of having cardiovascular disease as higher than normal if said level of said TMANO in said plasma or serum sample is higher than 4.1 μM.