Patent ID: 9255268
Filing Date: 2016-02-09
CPC Classification: A61K,C12N,C12Q

Claim Text:
1. A method for diagnosing susceptibility to developing a learning or mental disorder comprising (a) obtaining a biological sample from a subject; (b) determining the level of at least one microRNA (miR) gene product selected from the group of miR-25, miR-98 and miR-185 with a miR-25 oligonucleotides consisting of SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9 and SEQ ID NO:35, miR-98 oligonucleotides consisting of SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12 and SEQ ID NO:28, or a miR-185 oligonucleotides consisting of SEQ ID NO:13, SEQ ID NO:14 and SEQ ID NO:15, respectively; (c) comparing the level of microRNA in the biological sample to a control sample; and (d) diagnosing susceptibility to developing a learning or mental disorder, wherein a decrease in the level of the microRNA as compared to the control sample indicates that the subject is susceptible to developing a learning or mental disorder.