Patent ID: 9260420
Filing Date: 2016-02-16
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A heterocyclic compound represented by the formula wherein A is a lower alkylene group; in the monocyclic heterocycle containing Q is wherein R wherein Y R (1) an alkyl group, (2) a cycloalkyl group optionally substituted by a lower alkyl group, (3) a phenyl group, (4) a phenyl lower alkyl group (5) a lower alkoxy group, (6) a cycloaikyloxy group, (7) an amino group optionally having 1 or 2 substituents selected from the group consisting of an alkyl group and a phenyl lower alkyl group, or (8) a piperidyl group optionally haying a piperidyl group; at the 3-position and the 4-position of the bicyclic heterocycle skeleton containing Z and W is —CH═CH— or wherein R 6 and R 7 are the same or different and each is a hydrogen or a lower alkyl group; wherein R the following group wherein Y (1) a lower alkoxycarbonyl group or (2) a lower alkyl group, Y Y R3 is (1) an alkyl group, (2) a halogen-substituted lower alkyl group, (3) an alkenyl group, (4) an amino lower alkyl group, (5) a cycloalkyl group, (6) a phenyl group, (7) a phenyl lower alkyl group, (8) a piperidyl group optionally having 1or 2substituents selected from the group consisting of a lower alkyl group and a piperidyl group, (9) a halogen-substituted piperidyl group, (10) a morpholinyl group, (11) a pyrrolidinyl group, (12) a tetrahydropyranyl group, (13) a furyl group, (14) a thienyl group, (15) a pyridyl group, (16) a pyrimidinyl group, (17) a pyridazinyl group, (18) a benzofuryl group, (19) a quinolyl group, (20) a lower alkoxycarbonyl lower alkyl group, (21) a lower alkoxy lower alkoxy lower alkyl group, (22) a lower alkoxy lower alkoxy lower alkoxy lower alkyl group, (23) an amino group optionally having 1 or 2 substituents selected from the group consisting of an alkyl group, a cycloalkyl group, a cycloalkyl lower alkyl group, a lower alkenyl group, a halogen-substituted lower alkyl group, a lower alkoxy group, a lower alkoxy lower alkyl group, a lower alkoxycarbonyl lower alkyl group, a phenyl lower alkyl group, a phenyl lower alkoxy group, a furyl lower alkyl group, a pyridyl lower alkyl group, a hydroxy-substituted lower alkyl group, (24) an amino lower alkyl group optionally having a lower alkylcarbonyl group, (25) a piperazinyl group optionally having a lower alkyl group, or (26) the following group wherein Ac is an alkylene group, and other symbols are defined above, R (1) an alkyl group, (2) a phenyl group, (3) a phenyl lower alkyl group, (4) a halogen-substituted lower alkyl group, or (5) a cycloalkyl group, R (1) a hydrogen, (2) a lower alkyl group, (3) a halogen-substituted lower alkyl group, (4) a phenyl lower alkyl group, (5) a phenyl lower alkoxy lower alkyl group, (6) a tri-lower alkylsilyl group, (7) a tetrahydropyranyl group, or (8) a phosphono group, R (1) an alkenyl group, (2) a phenyl lower alkyl group, (3) a hydroxy-substituted lower alkyl group, (4) a cycloalkyl group, (5) an amino lower alkyl group optionally having (6) a pyrrolidinyl group optionally having an amino lower alkylcarbonyl group, (7) an alkoxy group, (8) a lower alkoxy lower alkoxy lower alkyl group, (9) a lower alkoxy lower alkoxy lower alkoxy lower alkyl group, (10) a phenyl lower alkoxy group, (11) an amino group optionally having 1 or 2 substituents selected from the group consisting of an alkyl group, a hydroxy-substituted lower alkyl group and a phenyl lower alkyl group, (12) a morpholino group, (13) a piperazinyl group optionally having a lower alkyl group, (14) a piperidyl group optionally having a piperidyl group, or (15) a cycloalkyloxy group; provided when then R