Patent ID: 9421176
Filing Date: 2016-08-23
CPC Classification: A61K

Claim Text:
1. A method of increasing dextromethorphan plasma levels in a human being that is an extensive metabolizer of dextromethorphan in need of treatment with dextromethorphan, comprising: administering, once or twice a day to the human being, a combination of active agents comprising: 1) bupropion, hydroxybupropion, erythrohydroxybupropion, or threohydroxybupropion; and 2) dextromethorphan; wherein the combination of active agents is administered for at least 8 consecutive days; wherein about 40 mg to about 600 mg of dextromethorphan is administered per day; wherein administering the combination of active agents results in an AUC wherein administering the combination of active agents results in a C