Patent ID: 9441275
Filing Date: 2016-09-13
CPC Classification: C12Q,G01N

Claim Text:
1. A method of administering a statin dose to a human, comprising: obtaining a nucleic acid-containing test sample from a human, wherein the human is in need of statin therapy; conducting at least one genotyping assay of the sample so as to obtain at least the genotype data at position rs35599367 of CYP3A4 in the sample, wherein the at least one genotyping assay comprises hybridizing a tagged primer to DNA in the nucleic acid-containing test sample, amplifying the hybridized DNA and detecting the tagged primer; detecting a T allele at position rs35599367 of CYP3A4; and administering a statin dose to the human comprising a TT or TC genotype at position rs35599367 of CYP3A4 of less than 20 mg per day wherein the statin administered is a statin that depends on CYP3A4 for elimination.