Patent ID: 9278073
Filing Date: 2016-03-08
CPC Classification: A61K,A61P

Claim Text:
1. An oral dosage form comprising: coated beads, each coated bead comprising an inert bead, a coating comprising an opioid antagonist coated over the inert bead, and a coating comprising a sequestering material coated over the coating comprising the opioid antagonist, and an opioid agonist, wherein the dosage form is a capsule, the opioid agonist is oxycodone or a salt thereof, the opioid antagonist is naltrexone or a salt thereof, and 0.25 mg or more of naltrexone is released at 1 hour from the coated beads when the coated beads are crushed, and no detectable amount of naltrexone is released from the coated beads when tested intact, based on the dissolution at 1 hour in 900 ml of Simulated Gastric Fluid using a USP Type II (paddle) apparatus at 75 rpm at 37° C., wherein the coating comprising the sequestering material separates the opioid antagonist from the opioid agonist.