Patent ID: 9308203
Filing Date: 2016-04-12
CPC Classification: A61K,A61P

Claim Text:
1. A pressure-sensitive adhesive matrix patch device for the treatment or prevention of fungal toenails or fingernails or foot infections comprising: (a) an impermeable backing layer, (b) a matrix layer having a first surface and a second surface opposite the first surface, wherein the first surface is adhered to the backing layer and the second surface is adapted to be in diffusional skin contact with a dorsal site of an infected palm or foot, the matrix layer comprising: (i) a pressure-sensitive adhesive, wherein the pressure-sensitive adhesive is an acrylic adhesive; (ii) an amount of an antifungal agent sufficient to provide an antifungal effect contained in the adhesive, wherein the antifungal agent is selected from 2% to 8 % by weight of terbinafine and a combination of 2% to 8% by weight of terbinafine and 1% to 5% by weight of ketoconazole, based on weight of the matix layer; and (iii) 5% to 10% by weight of a permeation enhancer based on the weight of the matrix layer, wherein the permeation enhancer is lauryl lactate; and (c) a release liner; the device being adhesively secured to the dorsal side of the infected palm or foot for a time sufficient to deliver an effective amount of the antifungal agent to an area of infection.