Patent ID: 9328386
Filing Date: 2016-05-03
CPC Classification: C12Q,G01N

Claim Text:
1. A method for the treatment of cancer comprising: administering an effective amount of an inhibitor of a kinase of the Src family to a subject in need of such a treatment, wherein the subject in need of such treatment is identified by evaluating phosphorylation of integrin β4 (ITGB4) at one or more phosphorylation sites selected from S1518, S1457, T1455 and S1069 of ITGB4 in a sample of a subject suspected to suffer from cancer, suffering from cancer or being prone to suffer from cancer, and wherein an increase in phosphorylation of one or more phosphorylation sites compared to a control indicates responsiveness of the subject to the inhibitor of a kinase of the Src family.