Patent ID: 9234026
Filing Date: 2016-01-12
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A method of treating and/or inhibiting a hepatitis virus infection in a subject, comprising: selecting a subject with a hepatitis C virus infection, and administering to the subject a therapeutically effective amount of an isolated polypeptide, wherein a) the polypeptide comprises the amino acid sequence set forth as SEQ ID NO: 1, the polypeptide is between 29 and 66 amino acids in length, the polypeptide comprises an N-terminal cysteine, and the polypeptide can inhibit the entry of a hepatitis C virus into a cell, and/or b) administering to the subject a therapeutically effective amount of a dimer of two polypeptides wherein each of the of e tides has a c steine at its N-terminus, is 29 to 66 amino acids in length, and comprises the amino acid sequence set forth as SEQ ID NO: 1, wherein the polypeptides are linked by a covalent bond between the cysteines to form the dimer, and wherein the dimer can inhibit the entry of a hepatitis C virus into a cell, thereby treating and/or inhibiting the hepatitis C virus infection in the subject.