Patent ID: 9394355
Filing Date: 2016-07-19
CPC Classification: A23J,A23L,A23V,A61K,A61P,C07K

Claim Text:
1. A fibroin-derived protein composition that possesses enhanced stability in an aqueous solution, wherein: the primary amino acid sequences of the fibroin-derived protein composition differ from native fibroin by at least 6% with respect to the combined amino acid content of serine, glycine, and alanine; cysteine disulfide bonds between the fibroin heavy and fibroin light protein chains of fibroin are reduced or eliminated; a plurality of peptide chains in the protein composition terminate in amide (—C(═O)NH the composition has a serine content that is reduced by greater than 40% compared to native fibroin protein, wherein the serine content is at least about 5%; and wherein the average molecular weight of the fibroin-derived protein composition is less than about 60 kDa and greater than about 30 kDa.