Patent ID: 9290553
Filing Date: 2016-03-22
CPC Classification: A61K,A61Q,C07K,C12N,G01N

Claim Text:
1. A chimeric peptide comprising a first amino acid sequence from filaggrin-2 fused to a second amino acid sequence, wherein the first amino acid sequence represents a peptide represented by the amino acid sequence selected from the group consisting of SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, and SEQ ID NO: 15, and a homolog having a sequence identity of at least 85% to SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14 and SEQ ID NO: 15 and modifies the three-dimensional conformation of a complex formed by interaction of filaggrin-2 with skin aspartic protease.