Patent ID: 9333156
Filing Date: 2016-05-10
CPC Classification: A61K,A61P,A61Q

Claim Text:
1. A method for inhibiting progression of or ameliorating skin roughness, dry skin, wrinkles, sagging skin and flecks and/or atopic dermatitis, said method comprising: administering transdermally an external preparation for skin, wherein the external preparation for skin contains (A) an iron compound selected from the group consisting of ferrous citrate, iron sodium citrate, iron ammonium citrate, iron acetate, iron oxalate, ferrous succinate, iron and sodium succinate citrate, ferrous pyrophosphate, ferric pyrophosphate, heme iron, iron dextran, iron lactate, ferrous gluconate, iron sodium diethylenetriaminepentaacetate, iron ammonium diethylenetriaminepentaacetate, iron sodium ethylenediaminetetraacetate, iron ammonium ethylenediaminetetraacetate, iron triethylenetetraamine, iron sodium dicarboxymethylglutamate, and iron ammonium dicarboxymethylglutamate in an amount of 0.5 to 50 wt % based on the total weight of the external preparation for skin, and (B) 5-aminolevulinic acid, a pharmaceutically acceptable salt of 5-aminolevulinic acid or a pharmaceutically acceptable ester derivative of 5-aminolevulinic acid or the salt thereof in an amount of 0.1 to 10 wt % based on the total weight of the external preparation, wherein each component of the preparation is administered transdermally either simultaneously or immediately sequentially in a same location of the skin.