Patent ID: 9441200
Filing Date: 2016-09-13
CPC Classification: A61K,A61L,A61P,C12N

Claim Text:
1. A method for preparation of an acellular adipose biocompatible biomaterial or processed adipose tissue (PAT) consisting of sequentially: a) providing mammalian tissue comprising solid adipose tissue; b) isolating the adipose tissue from the non-adipose tissue; c) decellularizing the adipose tissue and extracting lipid from the adipose tissue by contacting the adipose tissue with a decellularization agent selected from the group consisting of a weak acid, a weak organic acid, and a bile acid and manipulating the adipose tissue in the presence of the decellularization agent; d) washing the adipose tissue of c) by contacting the adipose tissue with a buffer and manipulating the adipose tissue in the presence of the buffer to remove the decellularization agent of c) and promote lipid and cell removal; e) optionally repeating steps c) and d) one or more times; and f) obtaining an acellular adipose biocompatible biomaterial which is acellular, lipid-free and retains the existing native structure and bioactivity of the extracellular matrix.