Patent ID: 9309551
Filing Date: 2016-04-12
CPC Classification: C12Q,G01N

Claim Text:
1. A method of manufacturing an analyte sensor for measuring glucose concentration in a bio-fluid, the method comprising: providing a sensor member in the form of a fiber including a core formed of conductive material surrounded by a cladding formed of a semiconductor material including silicon carbide; providing a surface region of enhanced electrochemical activity on the cladding of the sensor member by applying heat via laser to a portion of a surface of the sensor member sufficient to alter a response to an analyte of the cladding exposed to the heat to be five or more times greater than before exposure; and providing an active region over at least a portion of the surface region of enhanced electrochemical activity, the active region including an agent selected from among glucose oxidase, glucose dehydrogenase (GDH), pyrolloquinoline quinine (PQQ), and flavin adenine 25 dinucleotide (FAD), and being adapted to be exposed to a bio-fluid sample.