Patent ID: 9403837
Filing Date: 2016-08-02
CPC Classification: C07D

Claim Text:
1. A method for preparing a compound of formula 1: or a salt thereof, which method comprises the steps of: a) contacting a compound of formula 1a with a compound of formula 1b, wherein X is a palladium reactive functional group or precursor thereof, R under anhydrous reductive amination reaction conditions to yield a compound of formula 1c: b) contacting a compound of formula 1c with a cyclization catalyst under cyclizing conditions to yield a compound of formula 1d: c) contacting a compound of formula 1d under olefin arylation conditions to yield a compound of formula 1e: d) contacting a compound of formula 1e under deprotection conditions to yield a compound of formula 1; and e) optionally converting compound of formula 1 to a salt thereof.