Patent ID: 9428725
Filing Date: 2016-08-30
CPC Classification: B01L,C12M,C12N,G01N

Claim Text:
1. A flow-through device for capturing a biological material from a fluid specimen and lysing the fluid specimen, the device comprising: a first chamber containing: a portion of the fluid specimen; a solid phase material retained in the first chamber, the solid phase material having an affinity for the biological material in the fluid specimen; wherein the first chamber comprises: an inlet opening allowing flow of the fluid specimen into the first chamber; a first fitting attached to the inlet opening of the first chamber, the first fitting having a first thin filter insert that retains the solid phase material while allowing rapid flow of the fluid specimen at low pressure; an outlet opening allowing flow of the fluid specimen out of the first chamber; and a second fitting attached to the outlet opening of the first chamber, the second fitting having a second thin filter insert that retains the solid phase material while allowing rapid flow of the fluid specimen at low pressure; and a second chamber fluidly coupled to the first chamber, the second chamber containing: a portion of the fluid specimen; wherein the second chamber comprises: an impeller which in use imparts rotational motion to the fluid specimen to mechanically lyse the fluid specimen.