Patent ID: 9504760
Filing Date: 2016-11-29
CPC Classification: A61K,A61P

Claim Text:
1. A method for the treatment of an allergic or inflammatory disease of the lower airways in a mammal, comprising administering to the mammal a therapeutic effective amount of a pharmaceutical composition via inhalation, comprising a pharmaceutically acceptable polymerized protein-based nanocarrier and as active agent a guanidine phosphodiester cytosine (CpG) oligodeoxynucleotide (ODN), wherein the CpG ODN is a class A CpG ODN, wherein the polymerized protein-based nanocarrier is a gelatin nanoparticle, an albumin nanoparticle, a legumin nanoparticle, a gliadin nanoparticle, a beta-galactoglobuline nanoparticle or a silk protein nanoparticle, and wherein the class A CpG ODN is bound to the surface of the polymerized protein-based nanocarrier reversibly via electrostatic interaction, and wherein the method has a therapeutic effect in the treatment of an allergic or inflammatory disease of the lower airways of at least 4 weeks.