Patent ID: 9238837
Filing Date: 2016-01-19
CPC Classification: C12Q,G01N

Claim Text:
1. A method for determining a time of an acute kidney injury, comprising a. obtaining a test sample from a subject; b. determining, in said test sample, whether biomarkers Chac1 and/or Angptl7 are expressed above baseline levels and/or whether biomarker Birc5 is expressed above a baseline level, and c. determining, based on results obtained in b, the time when said acute kidney injury in said subject occurred, wherein the acute kidney injury occurred (i) between 0 and 36 hours before obtaining said test sample in a., when biomarkers Chac1 and/or Angptl7 are expressed above the baseline levels and/or (ii) between 0 and 120 hours before obtaining said test sample in a., when the biomarker Birc5 is expressed above the baseline level, wherein subsequent to the determining in c., renal injuries are treated or wherein when elevated levels of Chac1 and/or Angptl7 are detected, kidney-protective therapy is instituted.