Patent ID: 9408565
Filing Date: 2016-08-09
CPC Classification: A61B,B01L,C12Q,G01N

Claim Text:
1. An apparatus for detecting tumor cells in a biological subject, comprising a system for delivering the biological subject and a probing and detecting device; wherein the system for delivering the biological subject comprises a channel or a chamber; wherein the probing and detecting device comprises a first probing micro-device, a first detecting micro-device, and a substrate supporting the first probing micro-device or the first detecting micro-device; wherein the first probing micro-device is configured to apply a signal to the biological subject, such that said first probing micro-device is configured to stimulate the biological subject and cause it to have an intrinsic response, without causing any permanent chemical or structural damage to the biological subject; wherein the first detecting micro-device is configured to impinge the surface of the biological subject to be detected and measures at the microscopic level a property of the biological subject, and this property is related to the intrinsic response; wherein the substrate defines a part of the channel or the chamber, and the first probing micro-device and the first detecting micro-device are enclosed within and attached to a sidewall of the channel or the chamber; wherein the first probing micro-device or the first detecting micro-device comprises integrated electrical components or is connected to an electrical circuitry.