Patent ID: 9389217
Filing Date: 2016-07-12
CPC Classification: B01J,B01L,B81B,B81C,B82Y,C12Q,G01N,Y10S

Claim Text:
1. A method of analyzing at least one macromolecule, comprising the steps of: transporting at least one macromolecule in a fluid sample into a nanochannel, such that the at least one macromolecule is in an elongated state within the nanochannel; maintaining the at least one entire macromolecule in an elongated state within a region of the nanochannel having a substantially constant width and a substantially constant trench depth, wherein the width of the nanochannel is less than 100 nanometers and the trench depth of the nanochannel is less than 100 nanometers; detecting at least one signal from the at least one elongated macromolecule within the nanochannel; and correlating the detected signal to at least one property of the at least one macromolecule.