Patent ID: 9446084
Filing Date: 2016-09-20
CPC Classification: A61K,A61P

Claim Text:
1. A method for treating skin damage caused by chemotherapeutic treatment in a mammal in need thereof, wherein the skin damage is palmar-plantar erythrodysesthesia syndrome (PPE), comprising topically applying to affected skin of the mammal a therapeutically effective amount of a topical pharmaceutical composition comprising: i.) free radical scavengers in an amount of 3-33% by weight based upon topical pharmaceutical composition total weight; and ii.) microparticles in an amount of 0.6 to 8% by weight based upon the topical pharmaceutical composition total weight, wherein the microparticales are carrier material, and wherein said microparticales have an average particle size ranging from 5 to 200 μmm, and wherein said microparticles are horny sponge, or a mixture of bamboo and kaolin; wherein the free radical scavengers are selected from the group consisting of: (1) β-carotene; (2) a mixture of: (3) a combination of (1) and (2); and wherein the topical pharmaceutical composition is administered prior to, during and/or after chemotherapeutic treatment with cytostatic agents.