Patent ID: 9272049
Filing Date: 2016-03-01
CPC Classification: A61K,A61P,C12N,G01N

Claim Text:
1. A method of stimulating fat mobilization, the method comprising the steps of: providing a polyphenol; conjugating the polyphenol to a polymer selected from the group consisting of polyethylene glycol, polyglycolide, polylactide, polyvinyl alcohol, polyacrylic acid, hyaluronic acid and polyamidoamine; administering to a subject suffering from dyslipidemia, the polyphenol conjugated to the polymer; and binding the polyphenol conjugated to the polymer to a protein comprising an amino acid sequence Arg-Gly-Asp (RGD) recognition site, leading to increased phosphorylation of AMP kinase (AMPK), stimulating fat mobilization.