Patent ID: 9358272
Filing Date: 2016-06-07
CPC Classification: A61K,A61P

Claim Text:
1. A method for treating cancer in an animal in need thereof comprising administering a multicomponent composition to the animal, wherein the multicomponent composition comprises a first component and a second component, where the first component is a composition comprising a notch influencing molecule and the second component is a composition comprising a GPCR targeted molecule, wherein the GPCR targeted molecule is selected from SST-14, an SST analog, or a molecule of Formula (I),  where X is Y is a bond or where A 1 is —CH 2 —CH 2 —NH 2 , —CH 2 —CH 2 —NH—CH 3 , —CH 2 —CH 2 —N—(CH 3 ) 2 , —CH 2 —CH 2 —CH 2 —NH 2 , or —CH 2 —CH 2 —OH; Z is a bond, {linked to Y}-NMeAmEtGly-Gaba-{linked to Q}, {linked to Y}-Gly-(Gaba)-{linked to Q}, {linked to Y}-(Gaba)-{linked to Q}, {linked to Y}-(D-Lys)-(D-Tyr)-Lys-(D-Tyr)-(D-Lys)-{linked to Q}, or {linked to Y}-(D-Ser)-(Nle)-(D-Tyr)-(D-Ser)-{linked to Q}; and Q is