Patent ID: 9388439
Filing Date: 2016-07-12
CPC Classification: C12N,C12P

Claim Text:
1. An isolated nucleic acid having a sequence selected from: a sequence with at least 90% identity to SEQ ID NO: 1 and comprising at least one substitution, addition and/or deletion relative to SEQ ID NO: 1, wherein said sequence encoding a protein which is capable of converting phytosphingosine to triacetylphytosphingosine by transfer of the acetyl residues from three molecules of acetyl coenzyme A, and a sequence which hybridizes with SEQ ID NO: 1 under stringent conditions, wherein said stringent conditions include incubation at 68 degrees Celsius in 2× Saline-Sodium Citrate (SSC) Buffer or incubation at 65 degrees Celsius in 7% sodium dodecyl sulfate (SDS), 1% bovine serum albumin (BSA), 1 mM Ethylenediaminetetraacetic acid (EDTA) and 250 mM sodium phosphate buffer and washing at 65 degrees Celsius with 0.2×SSC and 0.1% SDS, and wherein said sequence codes for a protein which is capable of converting phytosphingosine to triacet¥lphytosphingosine by transfer of the acetyl residues from three molecules of acetyl coenzyme A.