Patent ID: 9284358
Filing Date: 2016-03-15
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An isolated conotoxin peptide having the formula X1GX2CX3DPRX4X5X6X7CX8X9 (SEQ ID NO:2), wherein: X1 is des-X1, pyroglutamic acid, Tyr, mono-halo-Tyr, or a fluorescent tag; X2 is Cys, selenocysteine (sel), or homocysteine; X3 is Ser, Thr, Ala, Tyr, halo-Tyr, Asn, Ile, or Arg; X4 is Cys or sel; X5 is Arg, citrulline, ω-nitro-Arg, homo-Arg, ornithine, or δ-N-acetyl-ornithine; X6 is Tyr, mono-halo-Tyr, Trp, or Phe; X7 is Arg, Gln, or His; X8 is Leu, Glu, Gln, or Lys; and X9 is des-X9, Tyr, mono-halo-Tyr, or a fluorescent tag; with the proviso that the conotoxin peptide of SEQ ID NO:2 is not a conotoxin peptide having the formula: GCCSDPRCRYRCK (SEQ ID NO:8).