Patent ID: 9421317
Filing Date: 2016-08-23
CPC Classification: A61M

Claim Text:
1. A biological fluid filter device comprising: (a) a housing comprising an inlet port, an upstream chamber, a downstream chamber, and an outlet port and defining a first fluid path between the inlet port and the outlet port, the housing further comprising an elution fluid inlet port and a drain port and defining a second fluid flow path between the elution fluid inlet port and the inlet port; (b) a porous fibrous leukocyte depletion filter having an upstream surface and a downstream surface, disposed in the housing across the first fluid flow path and across the second fluid path; (c) a perforated diffusing plate having a first surface and a second surface, disposed in the housing across the first fluid flow path and across the second fluid path, wherein the perforated diffusing plate has asymmetrically shaped perforations through the perforated diffusing plate, the first perforated diffusing plate being disposed between the downstream surface of the porous fibrous leukocyte depletion filter and the outlet port; wherein the inlet port is upstream of the upstream surface of the porous fibrous leukocyte depletion filter, the outlet port, the elution fluid inlet port, and the drain port, are downstream of the downstream surface of the porous fibrous leukocyte depletion filter and the perforated diffusing plate, and the drain port, in fluid communication with the downstream chamber of the biological fluid filter device, arranged to pass leukocyte-depleted biological fluid from the downstream chamber.