Patent ID: 9427407
Filing Date: 2016-08-30
CPC Classification: A61K,A61P

Claim Text:
1. A method for treating pain, and reducing or preventing nausea or vomiting associated with an opioid analgesic, the method comprising administering a solid oral pharmaceutical composition to a subject in need thereof, wherein the solid oral pharmaceutical composition comprises: a layer formulated for immediate-release comprising an antiemetic, wherein the antiemetic is promethazine or a pharmaceutically acceptable salt thereof that is present in an amount of about 12.5 mg or 25 mg; and a layer formulated for controlled-release comprising an opioid analgesic that is present in an amount of 1 mg to about 20 mg and a non-opioid analgesic that is present in an amount of about 200-600 mg, wherein the solid oral pharmaceutical composition provides an effective amount of the antiemetic to reduce or prevent nausea associated with the opioid analgesic or vomiting associated with the opioid analgesic in the subject in need thereof, and an effective amount of the opioid analgesic and the non-opioid analgesic to treat pain in the subject in need thereof.