Patent ID: 9260720
Filing Date: 2016-02-16
CPC Classification: A24B,C12N

Claim Text:
1. A genetic construct comprising a promoter operably linked to at least one coding sequence, which encodes at least one polypeptide having cytosolic pyruvate orthophosphate dikinase (PPDK) activity, wherein the promoter is a senescence-specific promoter, and wherein the coding sequence, which encodes the polypeptide having cytosolic PPDK activity, comprises a nucleic acid sequence as set out in SEQ ID No. 20, SEQ ID No. 21, or a functional variant or fragment thereof, the variant or fragment encoding the polypeptide having cytosolic PPDK activity and having at least 95% sequence with SEQ ID No. 20 or SEQ ID No. 21, or wherein the polypeptide having cytosolic PPDK activity comprises an amino acid sequence as set out in SEQ ID No. 23, or a functional variant or fragment thereof, the variant or fragment comprising the polypeptide having cytosolic PPDK activity and having at least 95% sequence identity with SEQ ID No. 23.