Patent ID: 9499597
Filing Date: 2016-11-22
CPC Classification: A61K,A61P,C07K,C12N

Claim Text:
1. A non-naturally occurring zinc finger protein consisting of 4, 5 or 6 zinc finger domains ordered F1 to F4, F1 to F5 or F1 to F6, respectively, wherein the zinc finger protein binds to an Htt gene and comprises one- or two-finger domains at positions F 2 or F2 and F3, the two-finger domains comprising the recognition helix regions sequences in F2 and F3 as shown in a single row of Table 2C and the one-finger domain of F2 comprising MACCRYA (SEQ ID NO:175); RSANLRE (SEQ ID NO: 176): RNADRKK (SEQ ID NO:177); RSDVLSE SEQ ID NO:42); RSAVLSE (SEQ ID NO:148): QSGDLTR (SEQ ID NO:18); QNATRIK (SEQ ID NO:178) or QSSDLSR (SEQ ID NO:31).