Patent ID: 9393396
Filing Date: 2016-07-19
CPC Classification: A61B,A61F,A61K,A61M,A61N,B82Y,G01R

Claim Text:
1. A method using hyperthermal therapy for at least one of delivery of a therapeutic agent to a cell in a patient in need thereof, the method comprising the steps of: providing a targeted nanoparticle-agent to form a nanoparticle-agent-cell complex at a site, thereafter exposing the site to an energy source under conditions sufficient to achieve a temperature of the complex, for about 1 femtosecond to about 15 minutes, the temperature sufficient result in agent release from the complex to the cell by at least one of thereafter assessing the acoustic sound produced from the nanoparticle at the site and, correlating the acoustic sound with the presence or absence of viable cells at the site by photoacoustic imaging and/or ultrasound spectroscopy.