Patent ID: 9526760
Filing Date: 2016-12-27
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A purified peptide which is a fragment of full-length lens epithelium derived growth factor (LEDGF), selected from the group consisting of: (a) a first peptide consisting essentially of N-terminal amino acids of (LEDGF) wherein the N-terminal amino acids are amino acids 1-326 (LEDGF (b) a second peptide having the N-terminal stress related binding domain of the full-length LEDGF, wherein the second peptide has an amino acid sequence with at least 80%, at least 85%, at least 90%, or at least 95% sequence identity to the amino acid sequence of LEDGF (c) a third peptide having the N-terminal stress related binding domain and TAT binding domain of the full-length LEDGF, wherein third peptide has an amino acid sequence with at least 80%, at least 85%, at least 90%, or at least 95% sequence identity to the amino acid sequence of LEDGF (d) a fourth peptide having more than said amino acids 1-326, wherein the purified peptide does not show a decrease in biological activity or stability during biosynthesis or production and purification relative to the full-length LEDGF.