Patent ID: 9241969
Filing Date: 2016-01-26
CPC Classification: A61K,A61P

Claim Text:
1. A method for treating a celiac patient, comprising: administering a peptide having the amino acid sequence of SEQ ID NO:1 to the duodenum of the patient; wherein the peptide is formulated as an oral dosage, delayed-release composition that contains peptide-coated beads having a delayed release coating that is a 1:1 co-polymer of methacrylic acid and ethyl acrylate and which is stable in gastric fluid and unstable in near neutral to alkaline environments so as to release peptide in the duodenum, and wherein at least 70% of the peptide in said beads is released upon exposure for 90 minutes to simulated intestinal fluid having a pH of greater than 5, and wherein the beads contain 0.1 to 0.8% by weight of said peptide.