Patent ID: 9284404
Filing Date: 2016-03-15
CPC Classification: A61K,A61P,C08G,Y10S

Claim Text:
1. An aqueous micelle mixture, comprising: about 5 to 500 micrograms/mL of a biodegradable cationic block copolymer, wherein the cationic block copolymer comprises i) a hydrophilic block comprising first repeat units derived from a first cyclic carbonyl monomer by organocatalyzed ring-opening polymerization, wherein the first cyclic carbonyl monomer is a cyclic carbonate and more than 0% of the first repeat units comprise a side chain moiety comprising a positively charged quaternary amine group, ii) a hydrophobic block comprising second repeat units derived from a second cyclic carbonyl monomer by organocatalyzed ring-opening polymerization, the second cyclic carbonyl monomer selected from the group consisting of cyclic carbonate monomers, cyclic ester monomers, and combinations thereof, iii) a chain fragment derived from an initiator for the ring opening polymerization, and iv) an optional endcap group; wherein the aqueous micelle mixture induces lysis of a microbial cell membrane, and the cationic block copolymer biodegrades 60% within 180 days in accordance with ASTM D6400.