Patent ID: 9457201
Filing Date: 2016-10-04
CPC Classification: A61B,A61H,A61N

Claim Text:
1. A method, comprising: non-invasively applying ultrasound energy to a cranium of a patient via first and second ultrasound transducers attached at disparate locations about the cranium of the patient; intravenously administering an acoustically active agent to the patient; exciting the acoustically active agent by the ultrasound energy to cause stable cavitation, controlling application of the ultrasound energy such that the first and second ultrasound transducers alternately apply the ultrasound energy in pulses to the cranium of the patient; during a time in which either the first or second ultrasound transducer is not applying ultrasound energy, detecting a state of cavitation of the acoustically active agent using the respective first or second ultrasound transducer, determining a type of cavitation from the detected state, and if the type of cavitation is inertial, whereby the application of the ultrasound energy has exceeded a level commensurate with a therapeutic window, then reducing an output power of the ultrasound energy until stable cavitation is detected; and if the type of cavitation is stable, then maintaining the output power of the ultrasound energy such that stable cavitation is maintained; wherein the non-invasive application of the ultrasound energy occurs at the site of an emergency and/or during transport to a care facility.