Patent ID: 9435790
Filing Date: 2016-09-06
CPC Classification: G01N

Claim Text:
1. A method of improving the viability and/or productivity of a cell in order to generate improved yields of cells or particular products expressed by a cell culture, the method comprising the steps of: contacting a cell population of the culture with carboxylated and/or amino dextran under conditions suitable to permit binding between the carboxylated and/or amino dextran and any dead cells or cells undergoing programmed cell death present in the cell culture, wherein the carboxylated and/or amino dextran is packed or provided in a column to which the cell population is added; removing at least some of the cell-bound carboxylated and/or amino dextran from said cell culture; and culturing the cell culture to provide an improved yield of cells and/or improved product expressed by the cells of the cell culture.