Patent ID: 9457048
Filing Date: 2016-10-04
CPC Classification: A23L,A23V,A61K,A61P,C08F

Claim Text:
1. A gastric bulking composition for oral delivery comprising a dissolvable capsule comprising non-digestible resin particles of a polyacrylic acid homopolymer or salt thereof crosslinked with a polyethylene glycol non-vinyl crosslinker; and a pharmaceutically acceptable excipient, wherein the resin particles have an average pre-swell size of from about 100 nm to about 1 mm, and wherein the composition exhibits a swelling ratio of at least 200 in free water within a gastric environment; and wherein from about 5% by weight to about 20% by weight of the total amount of resin particles in the composition are resin particles retained on a 500 micron mesh, from about 25% by weight to about 90% by weight of the total amount of resin particles in the composition are resin particles retained on a 180 micron mesh, and from about 1% by weight to about 15% by weight of the total amount of resin particles in the composition are resin particles retained on a 106 micron mesh.