Patent ID: 9522182
Filing Date: 2016-12-20
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method for the prophylaxis or treatment of porcine respiratory disease complex (PRDC) or one or more clinical signs of PRDC, selected from the group consisting of cough, dyspnea, slow growth, decreased feed efficiency, lethargy, anorexia, and/or a marked increase in mortality in the middle to late phase of fattening, in a group of porcine, wherein said PRDC is caused by PCV2 and at least one other PRDC causing pathogen, wherein the method comprises administering to a porcine in need a therapeutically effective amount of immunogenic composition comprising recombinant PCV2 ORF2 protein, wherein the porcine is between 1 and 22 days of age at the time of administration, wherein the therapeutically effective amount of recombinant PCV2 ORF2 protein comprises about 4 μg to 400 μg of recombinant PCV2 ORF2 protein, and wherein the recombinant PCV2 ORF2 protein is a polypeptide selected from the group consisting of: i. a polypeptide comprising the sequence of SEQ ID NO: 5, SEQ ID NO: 6, or SEQ ID NO: 11; ii. a polypeptide that is at least 90% homologous to the polypeptide of i), iii. a polypeptide that is encoded by a DNA comprising the sequence of SEQ ID NO: 3 or SEQ ID NO: 4; and iv. a polypeptide that is encoded by a polynucleotide that is at least 90% homologous to the polynucleotide of iii).