Patent ID: 9334488
Filing Date: 2016-05-10
CPC Classification: C12N,C12P,C12Y,Y02E,Y02P

Claim Text:
1. A yeast cell comprising a nucleic acid construct comprising a heterologous nucleic acid with a nucleotide sequence encoding a polypeptide that has xylose isomerase enzymatic activity, the expression of which polypeptide confers on, or increases in, the yeast cell the ability to directly isomerize xylose into xylulose, wherein the amino acid sequence of the polypeptide is at least 98% identical to SEQ ID NO:2 and comprises one or more conservative amino acid substitutions; wherein the one or more conservative amino acid substitutions is selected from the group consisting of valine to leucine or isoleucine, phenyalanine to tyrosine, lysine to arginine, alanine to valine, and asparagine to glutamine.