Patent ID: 9278077
Filing Date: 2016-03-08
CPC Classification: A61K

Claim Text:
1. An oral polymeric delivery vehicle for transmucosal delivery of a bioactive agent in a mammalian subject, comprising: a bioactive agent which is encapsulated by a polymeric coating, wherein the polymeric coating comprises molecules of alginate and transmucosal delivery enhancing molecules, wherein the transmucosal delivery enhancing molecules are covalently conjugated to the alginate molecules and extend from the surface of the polymeric coating, wherein the polymeric coating is resistant to degradation within the stomach and within the lumen of the small intestine, such that the polymeric delivery vehicle is capable of transmucosal passage across the intestinal mucosa into the intestinal bloodstream wherein the polymeric coating is degraded to release substantially all of the bioactive agent into the intestinal bloodstream; and wherein the transmucosal delivery enhancing molecules comprise at least one of an isoprenoid compound, a vitamin, or a fatty acid having 6-28 carbon atoms.