Patent ID: 9493402
Filing Date: 2016-11-15
CPC Classification: A61K,A61P,C07B,C07C,C07D

Claim Text:
1. A pharmaceutical composition consisting of (R)-2-Aryl-propionamide compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein Ar is a group selected from 4-isobutylphenyl, 2-(2,6-dichloro-phenyl-amino)-phenyl, or a phenyl 3-substituted with a group selected from the group consisting of benzoyl, isopropyl, isobutyl, pent-3-yl, 1-phenylethylen-1-yl, α-methylbenzyl, α-hydroxybenzyl, and α-hydroxyethyl, R represents hydrogen, X together with the nitrogen atom of the omega amino group to which it is bound and with the R as the active ingredient in admixture with pharmaceutically acceptable excipients and diluents, wherein the compound of the formula (I) has activity of inhibition of C5a-induced chemotaxis of polymorphonucleate leukocytes and monocytes and is devoid of any significant activity of inhibition of a cyclooxygenase enzyme.