Patent ID: 9480641
Filing Date: 2016-11-01
CPC Classification: A61K,A61Q

Claim Text:
1. A method of manufacturing a medicine for treatment of halitosis, said medicine being applicable to saliva secreted into oral cavity, said method comprises: (a) determining a target salivation rate at which said saliva secreted into said oral cavity; (b) selecting a desired effective duration time for a single serving dosage of said medicine, wherein during said desired effective duration of time a concentration of said medicine in said saliva within said oral cavity is sufficient to effectively prevent halitosis; (c) calculating or defining a diffusion coefficient of an appropriate pharmaceutical excipient configured to dissolve at a predefined dissolution rate within said saliva; (d) respectively defining or calculating a total mass of said pharmaceutical excipient to be used for said single serving dosage of said medicine; (e) calculating a total mass of an active ingredient to be used for said single serving dosage of said medicine in combination with said pharmaceutical excipient, wherein said active ingredient comprises a herbal composition comprising: (f) formulating said pharmaceutical excipient and said active ingredient into said single serving dosage of said medicine.