Patent ID: 9421277
Filing Date: 2016-08-23
CPC Classification: A61K,A61P,C07K,G01N

Claim Text:
1. A method of treating cancer that expresses OV064 in a subject, comprising administering to the subject an anti-OV064 antibody molecule, or an antigen binding fragment thereof, wherein the anti-OV064 antibody molecule or antigen binding fragment is conjugated to a cytotoxic moiety, in an amount sufficient to reduce or inhibit the growth of the subject's cancer; wherein the anti-OV064 antibody molecule or antigen binding fragment comprises: (a) three heavy chain complementarity determining regions (HCDR1, HCDR2, and HCDR3) comprising amino acid sequences: SEQ ID NO: 16 (HCDR1), SEQ ID NO: 17 (HCDR2), and SEQ ID NO: 18 (HCDR3); and (b) three light chain complementarity determining regions (LCDR1, LCDR2, and LCDR3) comprising amino acid sequences: SEQ ID NO: 25 (LCDR1), SEQ ID NO: 26 (LCDR2), and SEQ ID NO: 27 (LCDR3).