Patent ID: 9382538
Filing Date: 2016-07-05
CPC Classification: A61P,C12N,C12Q,G01N

Claim Text:
1. A synthetic, modified oligonucleotide of 16 to 30 nucleotides in length comprising at least one modification wherein the at least one modification is selected from: at least one modified sugar moiety; at least one modified internucleotide linkage; at least one modified nucleotide, and combinations thereof; wherein said oligonucleotide is an antisense compound which specifically hybridizes and shares 100% complementarity over the full length to (1) a region of a polynucleotide of a mammalian Colony-stimulating factor 3 (CSF3) polynucleotide having SEQ ID NO: 1 or 2 or (2) a region of a natural antisense polynucleotide of said CSF3 polynucleotide having SEQ ID NO: 1 or 2 and upregulates the function and/or expression of a Colony-stimulating factor 3 (CSF3) polynucleotide in mammalian cell or tissues in vivo or in vitro as compared to a normal control, and wherein said modified oligonucleotide is not a primer or probe.