Patent ID: 9233995
Filing Date: 2016-01-12
CPC Classification: A61P,C07D,C07F

Claim Text:
1. A quinazoline complex as protein kinase inhibitor, formed by coordinating a coordination compound containing noble metal and a ligand capable of coordinating with the noble metal in the coordination compound, wherein said ligand is quinazoline having a molecular structure represented by formula (1): wherein m is 0, R′ is hydrogen, and R is a group containing at least one atom capable of coordinating with noble metals and is any one selected from the group consisting of a fused heterocyclic imino or substituted fused heterocyclic imino, an aminoalkyl imino, a group having an imidazole type five-membered heterocyclic structure and on the ring a tertiary amino group, and a six-membered aromatic heterocyclic imino or substituted six-membered aromatic heterocyclic imino, where a nitrogen in said imino or tertiary amino group bonds to the 6-oxygen of the alkyl chain, and n is an integer from 0 to 5; alternatively, both R and R′ are —NH wherein the noble metal is ruthenium and/or platinum.