Patent ID: 9289492
Filing Date: 2016-03-22
CPC Classification: A61K,C12N,G01N

Claim Text:
1. A method for collecting a population of ovarian cancer stem cells, the method comprising (i) contacting a biopsy tissue sample comprising a population of ovarian cancer cells with an anti-EpCam, an anti-cytokeratin-8 and an anti-β-catenin antibody, antibody derivative or fragment thereof; (ii) separating the ovarian cancer cells that are positive for binding the combination of anti-EpCam, anti-cytokeratin-8, and anti-β-catenin antibodies, from the ovarian cancer cells that do not bind all three of the antibodies; (iii) collecting the ovarian cancer cells that are positive for the binding of the combination of anti-EpCam, anti-cytokeratin-8, and anti-β-catenin antibodies, wherein the isolated ovarian cancer cells comprises ovarian cancer stem cells.