Patent ID: 9493545
Filing Date: 2016-11-15
CPC Classification: A61P,C07K,G16B

Claim Text:
1. A conjugation competent polypeptide comprising up to and including five conjugation competent cysteine residues, a) wherein said polypeptide comprises an albumin sequence having at least 96% sequence identity to SEQ ID NO: 1; and b) wherein said polypeptide is a mutant comprising a Cysteine at or immediately following an amino acid residue in the albumin sequence which corresponds to the second, third, fourth or fifth residue relative to the N- or C-terminus of the albumin sequence; and/or c) wherein the polypeptide is a mutant comprising a Cysteine at or adjacent to an amino acid residue in the albumin sequence which: d) optionally, wherein the polypeptide comprises additional alterations to the albumin sequence where each alteration is an amino acid deletion, substitution, or insertion; with the proviso that, where there are two or fewer conjugation competent cysteine residues within the polypeptide, such polypeptide does not include a cysteine at the position corresponding to position 1 of SEQ ID NO: 1.