Patent ID: 9278163
Filing Date: 2016-03-08
CPC Classification: A61K,A61L,A61P

Claim Text:
1. An implantable device for subcutaneous administration of a dopamine agonist to a mammal in need thereof, comprising a dopamine agonist and a biocompatible, nonerodible polymeric matrix, wherein said dopamine agonist is encapsulated within said matrix, wherein the implantable device is produced by an extrusion process, wherein said dopamine agonist and the polymer are blended, melted, and extruded into a structure, wherein the implantable device further comprises a coating of a nonerodible polymeric material having a lower dopamine agonist loading than the remainder of the implantable device, and wherein when said implantable device is implanted subcutaneously in said mammal, said dopamine agonist is continuously released in vivo over a sustained period of time through pores that open to the surface of said matrix at a rate that results in a plasma level of at least about 0.01 ng/ml for the sustained period of time, wherein the sustained period of time is at least about 3 months.