Patent ID: 9272251
Filing Date: 2016-03-01
CPC Classification: B01F,C12M

Claim Text:
1. An impeller for use in a bioreactor for adherent mammalian cells and/or a cell separator for adherent mammalian cells comprising: a hub attachable to a rotatable shaft; one or more blades attached to said hub; each said blade comprising: a first side adjacent to the hub; a second side and a third side adjacent to and at right angles to said first side, said second and third sides defining a height therebetween; a fourth side opposed to the first side and forming an outer edge of the blade, said outer edge disposed at a length from said hub; and a surface having a planar portion and a curved portion; wherein said curved portion is angled in the range of 70 to 120° to the plane of said planar portion to form a leading surface relative to the direction of rotation of said impeller, wherein the second side is shorter than the third side, wherein the impeller is configured to turn the mammalian cells at low shear force to minimize cellular injury, wherein the fourth side outer edge includes a generally straight portion merging into said curved portion; and said length being greater than said height.