Patent ID: 9488583
Filing Date: 2016-11-08
CPC Classification: G01N

Claim Text:
1. A molecular analysis device comprising: a substrate; a high-vertical-refractive-index-contrast waveguide on the substrate comprising a coupling means configured for coupling a predetermined frequency or range of frequencies of laser radiation into the waveguide and comprising a planar integrating element with a filter or reflector element adjacent to the integrating element arranged for reflecting said laser radiation, the waveguide and the planar integrating element having a height such that they are single mode out-of-plane; a metallic nanostructure disposed on top of or adjacent to the planar integrating element, positioned for being irradiated by said laser radiation coupled into the waveguide as well as said laser radiation reflected by said filter or reflector element, and configured such that the field intensity and the gradient of said laser radiation that is coupled into the guided mode of the waveguide, are enhanced over a volume around the nanostructure to cause both plasmonic based optical trapping of analytes in a medium and plasmonic based excitation of said particles to produce Raman scattered radiation; and a Raman scattered radiation collection means disposed on the substrate for collecting said Raman scattered radiation produced by said particles.