Patent ID: 9416228
Filing Date: 2016-08-16
CPC Classification: A61L,C08G,C08J,C08L

Claim Text:
1. A biocompatible tissue-adhesive medical product selected from the group consisting of adhesive tissue tape, an adhesive tissue film, a tissue sealant, a haemostatic material, a suture material, a polymer coated stent and an implant, comprising at least 1% by weight of dry matter of a covalently cross-linked polymer obtained by reacting a nucleophilically activated polyoxazoline (NU-PDX) with an electrophilic cross-linking agent other than an electrophilically activated polyoxazoline, said NU-PDX comprising m nucleophilic groups; and said electrophilic cross-linking agent comprising n electrophilic groups, wherein the m nucleophilic groups are capable of reaction with the n electrophilic groups to form covalent bonds; wherein m≧2, n≧2 and m+n≧5; wherein the total number of reacted and unreacted electrophilic groups contained in the polymer exceeds the total number of reacted and unreacted nucleophilic groups contained in the polymer by at least 3%; wherein the NU-PDX comprises at least 30 oxazoline units in case the electrophilic cross-linking agent is an isocyanate, and wherein the tissue-adhesive properties derive from a reaction of non-reacted electrophilic groups in the cross-linked polymer with nucleophilic groups present in the tissue.