Patent ID: 9365609
Filing Date: 2016-06-14
CPC Classification: C07J

Claim Text:
1. A process for preparing a crystalline form of halobetasol propionate, comprising the step of crystallizing a single batch of at least about 100 grams of halobetasol propionate by (a) heating to a reflux temperature, halobetasol propionate in absolute ethanol or a mixture of between about 80:20 and about 100:0 ethanol:water; (b) cooling the solution to induce precipitation, wherein the crystalline form of halobetasol propionate is characterized by an x-ray powder diffraction pattern having peaks at 10.0, 11.6, 12.9, 13.4, 14.5, 16.4, 17.6, and 23.5±0.2 degrees 2-theta.