Patent ID: 9463160
Filing Date: 2016-10-11
CPC Classification: A61K,A61P,B33Y

Claim Text:
1. A rapid release drug delivery system comprising: a non-compressed solid matrix having a three dimensionally printed architecture, the matrix comprising a bulk powder material, a water soluble binder and at least one active ingredient, and the active ingredient being present in one or more predetermined printed pattern within the matrix, wherein the matrix disperses in about 90 seconds or less upon contact with moisture thereby releasing the active ingredient, the matrix has a hardness of about 1 to about 20 kp, and the drug delivery system has a porosity of 10%-90%, wherein the matrix is prepared according to the process comprising: a) providing one or more layers comprising a mixture of bulk powder material and a water soluble binder; b) according to the one or more predetermined patterns, applying binding fluid to the one or more layers using a three-dimensional printing technique, the binding fluid comprising a pharmaceutically acceptable solvent and at least one active ingredient, or comprising a mixture of a pharmaceutically acceptable solvent and at least one active ingredient and water soluble pharmaceutically acceptable binder; and c) evaporating the solvent to provide a rapidly dispersing non-compressed solid matrix.