Patent ID: 9475789
Filing Date: 2016-10-25
CPC Classification: A61K,C07D

Claim Text:
1. A method for treating inflammation comprising administering a subject in need thereof with a therapeutically effective amount of a compound of formula (I): wherein R or a pharmaceutically acceptable salt thereof, wherein the compound of formula (I) is in a therapeutically effective amount to (i) inhibit production of nitric oxide (NO) or expression of inducible nitric oxide synthase (iNOS), interleukin-6 (IL-6) or tumor necrosis factor-α (TNF-α), (ii) inhibit NLRP3 inflammasome-mediated IL-1β expression, or (iii) inhibit reactive oxygen species (ROS) production, mitogen-activated protein kinase (MAPR) phosphorylation, NF-κB activation or protein kinase C (PKC) activation, in macrophages or dendritic cells of the subject.