Patent ID: 9498358
Filing Date: 2016-11-22
CPC Classification: A61F

Claim Text:
1. A medical device for delivery of a therapeutic agent with a combined release profile, the device comprising: an implantable body, wherein the implantable body includes an expandable stent that has a plurality of struts; one or more first through-openings formed in the plurality of struts containing a first beneficial agent for delivery to tissue, wherein the first beneficial agent comprises a therapeutic agent and a first matrix, wherein the therapeutic agent and the first matrix are arranged to deliver the therapeutic agent from the one or more first through-openings according to a first release curve; and one or more second through-openings formed in the plurality of struts containing a second beneficial agent for delivery to tissue, wherein the second beneficial agent comprises the therapeutic agent and a second matrix, wherein the therapeutic agent and the second matrix are arranged to deliver the therapeutic agent from the one or more second through-openings according to a second release curve which is different from the first release curve; wherein the one or more first through-openings are alternatively arranged relative to the one or more second through-openings along each of the plurality of struts, and the one or more first through-openings are alternatively arranged relative to the one or more second through-openings along a circumferential direction of the implantable body, and in each occurrence of the alternatively arranged one or more first through-openings and the respective one or more second through-openings, a number of openings in the one or more first through-openings and a number of openings in the one or more second through-openings are present in a ratio, wherein the plurality of struts include: wherein the one or more first through-openings are alternatively arranged relative to the one or more second through-openings along each strut of the third circumferential row of struts, and the one or more first through-openings are alternatively arranged relative to the one or more second through-openings on the third circumferential row of struts in the circumferential direction.