Patent ID: 9271925
Filing Date: 2016-03-01
CPC Classification: A61B,A61K,A61L,A61M,A61P,Y10T

Claim Text:
1. A device comprising: a first film-layer comprising fibrinogen, the first film-layer formed by processing a first composition comprising a first amount of non-aqueous solvent for a first time interval to produce a first characteristic selected from the group consisting of a release profile of one or more therapeutic agents over time, adhesiveness, solubility, matrix stiffness, porosity, and degradation rate of the first film-layer; optionally, an intermediate layer comprising an adhesive configured to bond to the first and second film-layers; and the second film-layer optionally bonded to the first film-layer, the second film-layer comprising fibrinogen, the second film-layer formed by processing a second composition comprising a second amount of non-aqueous solvent for a second time interval to produce a second characteristic selected from the group consisting of a release profile of one or more therapeutic agents over time, adhesiveness, solubility, matrix stiffness, porosity, and degradation rate of the second film-layer, wherein the second composition has the same composition as the first composition except the second amount of non-aqueous solvent is different from the first amount of non-aqueous solvent such that the second film-layer has a physical structure sufficient to produce the second characteristic which is different in value from the first characteristic of the first film-layer.