Patent ID: 9388472
Filing Date: 2016-07-12
CPC Classification: A61K,A61P,C12Q,G16B

Claim Text:
1. A method of treating cancer, comprising: (1) assaying a cancer cell sample obtained from a test breast or ovarian cancer patient to detect a test number of Indicator LOH Regions in at least ten pairs of human chromosomes, wherein an Indicator LOH Region is equal to or longer than a first length but shorter than the length of the whole chromosome containing the Indicator LOH Region, and wherein the first length is at least 5 megabases; (2) providing a test value equal to or derived from the test number of Indicator LOH Regions detected in (1); (3) determining that said test value exceeds a reference value equal to or derived from a reference number of Indicator LOH Regions in said at least ten pairs of human chromosomes in cancer cell samples of a population of reference breast or ovarian cancer patients, wherein said reference number of Indicator LOH Regions is at least five; and (4) administering to the test breast or ovarian patient a treatment regimen comprising one or both of a platinum chemotherapy agent or a PARP inhibitor drug.