Patent ID: 9242005
Filing Date: 2016-01-26
CPC Classification: A61K,A61M

Claim Text:
1. A method comprising: introducing a catheter device to a denuded or damaged endothelium treatment area in a blood vessel of a human subject, wherein the catheter device comprises a porous balloon and a cover member for covering a porous surface of the balloon, the cover member having a window through which a portion of the porous surface is exposed to allow for targeted delivery of a fluid solution through the porous surface; isolating the denuded or damaged endothelium treatment area in the blood vessel, wherein isolating comprises aligning the window with the denuded or damaged endothelium treatment area such that the porous surface is exposed to the treatment area; and after isolating, delivering the fluid solution to the denuded or damaged endothelium treatment area through the porous surface, the fluid solution comprising a pro-healing agent disposed within a biodegradable carrier, wherein the pro-healing agent is an extra-cellular binding protein, and wherein the pro-healing agent has a property that accelerates re-endothelialization, and wherein the carrier is one of a liposome, a polymerosome, a micelle or a particle.