Patent ID: 9297804
Filing Date: 2016-03-29
CPC Classification: G01N

Claim Text:
1. A method for removing α-amylase from an oral fluid sample in order to minimize or prevent the screening effects caused by said α-amylase in a laboratory assay of said oral fluid sample, said method comprising: contacting said oral fluid sample with starch under conditions enabling binding between the α-amylase and said starch, at a temperature of 15-35° C., wherein said starch is not bound to resin and is not chemically bound to another substrate; separating the starch-amylase bound complexes from the free components, thereby removing the bound α-amylase; wherein said contacting and said separating are achieved by means of passing said oral fluid through a filtering device loaded with said starch, wherein said starch is immobilized, applied or disposed on or above a filter that is a sheet of porous media; collecting the non-bound components in a filtrate having a decreased amount of α-amylase, thereby obtaining a fluid with a reduced α-amylase concentration; and using said fluid with reduced α-amylase concentration for testing of agents, bio-markers or hormones present in the fluid.