Patent ID: 9422338
Filing Date: 2016-08-23
CPC Classification: A61K,C07K

Claim Text:
1. An erythropoietin (EPO) mimetic comprising a first chain, a second chain and a linker wherein at least one of the first and second chains comprises: a. a loop, wherein the loop comprises a sequence selected from the group consisting of R-M-G-W-V (SEQ ID NO: 1); R-M-βA-W-V (SEQ ID NO: 2); R-M-F-W-V (SEQ ID NO: 3); R-M-homoF-W-V (SEQ ID NO: 4); R-M-L-W-V (SEQ ID NO: 5); R-M-nL-W-V (SEQ ID NO: 6); R-M-P-W-V (SEQ ID NO: 7); H-M-P-W-V (SEQ ID NO: 8); R-M-P-Nal-V (SEQ ID NO: 9); H-M-P-Nal-V (SEQ ID NO: 10); and R-M-P-X-V (SEQ ID NO: 11): and b. a bridge, wherein: wherein the linker is covalently bound to each of the first and second chains at sequence positions of, independently, from between about residue 5 to about residue 18.