Patent ID: 9518104
Filing Date: 2016-12-13
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A method for supressing macrophage infiltration, microglia activation or infiltration of leukocytes in the central nervous system (CNS) of a subject that exhibits multiple sclerosis-like symptoms of axonal damage, oligodendrocyte death, demyelination or a combination thereof comprising administering a polypeptide (a) comprising Asp153-Lys172 of the GluR2 N-terminus (DSDRGLSTLQAVLDSAAEKK (SEQ ID NO:5)) and wherein the polypeptide does not comprise SEQ ID NO:1 or (b) of between 31 and 200 amino acids comprising a GluR2 NT1-3-2 (Y142-K172) amino acid sequence defined by SEQ ID NO:1 to the subject to suppress macrophage infiltration, microglia activation or infiltration of leukocytes in the CNS of the subject.