Patent ID: 9295721
Filing Date: 2016-03-29
CPC Classification: A61K,A61P,C07K,C12N,Y02A

Claim Text:
1. A stabilized dry Haemophilus influenzae vaccine composition comprising micropellets or particles, wherein the micropellets or particles are grilled micropellets or particles with a diameter from about 200 μm to about 1500 μm, wherein the micropellets or particles are obtained by a process comprising, a) diluting a liquid bulk antigen composition comprising a conjugated or non-conjugated polysaccharide antigen or an antigenic preparation from b) prilling the diluted vaccine composition solution to form calibrated droplets of the vaccine having a diameter of approximately from about 200 μm to about 1500 μm, c) subjecting the droplets of the vaccine to freezing to form frozen spherical micropellets or particles of the vaccine, and d) drying the frozen spherical micropellets or particles of the vaccine to form dry spherical micro-pellets or particles of the vaccine having a diameter from about 200 μm to about 1500 μm.