Patent ID: 9403038
Filing Date: 2016-08-02
CPC Classification: A61B,A61N,C12N

Claim Text:
1. An ultrasound wave generating device for modulating neuronal cellular activity of a neuronal cellular site in a subject, comprising at least one component for generating an ultrasound wave, adapted to deliver a stimulus waveform to the neuronal cellular site; and a controller coupled to the at least one component, the controller comprising a process to determine the stimulus waveform delivered to the neuronal cells, wherein the controller is configured with the process to provide the stimulus waveform comprising a plurality of pulses, each pulse of the plurality comprising a plurality of cycles having one or more frequencies in a range from about 0.02 MHz to about 100 MHz at the site of the cells to be modulated, wherein said each pulse of the plurality of pulses comprises a plurality of frequencies and wherein pulses of the plurality are repeated at a pulse repetition frequency ranging from about 0.001 to about 100 kHz to produce spatial-peak temporal-average intensities of no more than 100 W/cm