Patent ID: 9366645
Filing Date: 2016-06-14
CPC Classification: G01N

Claim Text:
1. A method of detecting botulinum, comprising: preparing a cartridge including a high electron mobility transistor (HEMT) botulinum toxin sensor comprising a layer of gold on a gate region, thioglycolic acid anchored to a surface of the layer of gold, botulinum antibodies linked to the thioglycolic acid, and a fluidic path across the layer of gold on the gate region of the HEMT; providing the fluidic path with a sample; and generating a signal indicating detection of botulinum, wherein the HEMT is configured to be removable from the cartridge, and wherein the signal is generated by the sensor upon exposure of the botulinum antibodies to an amount of botulinum by transducing a change of a surface charge of the HEMT into a change in a concentration of two-dimensional electron gas in the HEMT.