Patent ID: 9265721
Filing Date: 2016-02-23
CPC Classification: A61K

Claim Text:
1. A spreadable gel or cream for topical application to a part of the body comprising a vasodilator as an active ingredient dissolved in a blend of volatile and non-volatile solvents of different solvating capacities for the active ingredient, wherein the volatile solvent comprises a mixture of water and a C 1 -C 5 alcohol in a ratio by weight of 1.6:1 to 2.5:1, the non-volatile solvent comprises glycerol in a concentration from 5 to 40% by weight of the total solvent content, and the spreadable gel or cream comprises between 0.015 mg and 5 mg of glyceryl trinitrate in a unit-dosage form, wherein the concentration of the vasodilator present in the total solvent system is at or slightly below a saturated concentration such that super-saturation occurs upon loss of volatile components.