Patent ID: 9381477
Filing Date: 2016-07-05
CPC Classification: A61K,B01F,B01J,B82Y

Claim Text:
1. A microfluidic system for producing organic particles comprising a device comprising a mixing apparatus and at least a center channel and an outer channel, and each channel has a cross-section independently selected from the group consisting of circular, oval, ovaloid, elliptical, and ellipsoid shapes, that converge into the mixing apparatus, wherein the width and height of each channel is between approximately 1 μm and approximately 1000 μm, and at least one polymer solution not containing particles, and a non-solvent fluid for each polymer not containing particles, wherein the polymer solution forms polymeric particles in the non-solvent fluid upon mixing, wherein the at least center and outer channels are positioned so that the polymer solution and non-solvent fluid flowing through each channel are directed at one another within the mixing apparatus, and wherein the position of the channels can be varied to alter the direction of the polymer solution or non-solvent fluid into the mixing apparatus, the device further comprising means for controlling the flow rates through the channels either using pumps or applying pressure to focus the polymer solution into a narrow stream having a width which is smaller than the channel width within the mixing apparatus, or wherein the mixing apparatus is selected from the group consisting of chaotic advection mixers, zigzag mixers, droplet mixers, shear superposition mixers, T-mixers, mixers based on Tesla structures, and active mixers, wherein the polymer solution forms polymeric particles in the mixing apparatus.