Patent ID: 9274059
Filing Date: 2016-03-01
CPC Classification: G01N

Claim Text:
1. An electrochemical device for combined electrochemical analysis and chemical imaging of analytes at an electrode-liquid sample interface in-situ under vacuum, comprising: an analytical instrument producing one or more probe beams; an electrochemical microfluidic flow chamber that defines a liquid flow path through the flow chamber, the flow chamber includes a support membrane with at least one detection aperture configured to expose a surface of a liquid sample containing one or more analytes to one or more probe beams delivered from analytical instrument when the liquid sample is introduced past the at least one detection aperture under vacuum, the one or more probe beams when delivered through the at least one detection aperture determines the one or more analytes at the surface of the liquid sample providing chemical imaging thereof; a working electrode configured to apply a selected potential into the liquid sample between the working electrode and a reference electrode that drives reactions of the one or more analytes in the liquid sample as a function of time, space, and/or potential; and a counter electrode configured to measure electrical current stemming from reactions involving the one or more analytes to provide electrochemical analysis and chemical imaging of the analytes in the liquid sample at the surface of the working electrode-sample interface in-situ.