Patent ID: 9421221
Filing Date: 2016-08-23
CPC Classification: A61K,A61L

Claim Text:
1. A matrix for reducing, preventing or treating adhesions in a patient in need thereof, the matrix comprising a biodegradable polymer and dextran sulfate loaded in the matrix in an amount of at least 70 wt. % based on a total weight of the matrix, wherein the matrix is configured to release from about 20% to about 90% of the dextran sulfate loaded in the matrix within 24 to 48 hours, and the matrix is in sponge form having a burst release surface that releases about 10% of the dextran sulfate over 24 hours, and the biodegradable polymer comprises purified type I bovine fibrillar collagen comprising from about 1.0 wt. % to about 2.0 wt. % based on a total weight of the matrix, and an average sulfur content for the dextran sulfate is between about 15 to 20%.