Patent ID: 9403830
Filing Date: 2016-08-02
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: A 1 and A 2 are each independently selected from the group consisting of CH and N; L 1 is a linker selected from the group consisting of —O— and —CH 2 —; B is a 9- or 10-membered ring selected from the group consisting of: wherein each B ring may optionally be further substituted by —(C 1 -C 6 )alkyl; L 2 is absent or a —(CH 2 ) n — linker, wherein n is an integer selected from 1, 2 and 3, and wherein one —(CH 2 )— moiety of said L 2 linker may optionally be replaced, where possible, by —O— and wherein each —(CH 2 )— of said L 2 linker may be substituted with one to two groups selected from the group consisting of —OH, -halo, ═O, —(C 1 -C 6 )alkyl, —(C 3 -C 6 )cycloalkyl, -(4- to 7-membered)heterocyclyl, and phenyl; wherein two —(C 1 -C 6 )alkyls groups, when attached to the same carbon atom of said L 2 linker moiety may join to form a —(C 3 -C 6 )cycloalkyl; R 1 is selected from the group consisting of: (a) a group of formula —N(R (b) a 4- to 9-membered N-heterocyclic ring, wherein said 4- to 9-membered N-heterocyclic ring is optionally independently substituted with one or more substituents selected from the group consisting of (i) 1 G (c) a group selected from the group consisting of a tetrahydro-2H-pyranyl, —C(O)—OH and OH; wherein j is an integer selected from 0, 1 and 2.