Patent ID: 9375420
Filing Date: 2016-06-28
CPC Classification: A61K

Claim Text:
1. A method of treating or preventing an infection in a patient in need of such treatment, the method comprising administering one or more biodegradable drug depots comprising a polymer and a therapeutically effective amount of a local anesthetic comprising bupivacaine or pharmaceutically acceptable salt thereof, the drug depot being administered at a site to reduce, prevent or treat an infection, wherein the drug depot is capable of releasing (i) a bolus dose of the local anesthetic or pharmaceutically acceptable salt thereof at the site from a layer, wherein between 15 and 25% of the bupivacaine is released within a 24 hour period and (ii) a sustained release dose of an effective amount of the local anesthetic or pharmaceutically acceptable salt thereof over a period of at least 4 days at the site, wherein the polymer comprises a particle size of about 10 μm to about 40 μm and is capable of degrading in less than 30 days after the drug depot is administered at the site.