Patent ID: 9342657
Filing Date: 2016-05-17
CPC Classification: A61K,G16B,G16H

Claim Text:
1. A method for treating cancer, comprising obtaining the results of a correlation between patient biological profile information and the predictive information of post-treatment efficacy for a particular treatment selected from one or more treatments for a cancer, wherein the particular treatment comprises a drug treatment, wherein the correlation is obtained by: i) identifying a group of patients who had the cancer and who underwent the particular treatment for the cancer's metastasis; ii) receiving multiple gene based pre-treatment biological profile information obtained through analysis of one or more of tissue and biological specimens obtained from the group of patients prior to the particular treatment; iii) receiving post-treatment efficacy information from the group of patients indicative of an impact of the particular treatment on the cancer's metastasis; iv) performing a discriminant analysis-based pattern recognition process on the multiple gene based pre-treatment biological profile information and the post-treatment efficacy information, including identifying discriminating features of the multiple gene based pre-treatment biological profile information that correlate to different post treatment efficacies, and including generating a prediction model for the particular treatment that maps the multiple gene based pre-treatment biological profile information, using the discriminating features, to the corresponding different post treatment efficacies for the cancer's metastasis; v) receiving multiple gene based pre-treatment biological profile information obtained through analysis of the one or more of tissue and biological specimens obtained from a new patient prior to the new patient receiving the particular treatment for the cancer; and vi) processing the new patient multiple gene based pre-treatment biological profile information according to the model, including using the discriminating features of the new patient multiple gene based pre-treatment biological profile information to predict an efficacy of the particular treatment for the new patient prior to the new patient receiving the particular treatment; wherein the multiple gene based pre-treatment biologic profile information and the post-treatment efficacy information are received within a suitably programmed computer system, and wherein the discriminant analysis-based pattern recognition process is performed within the suitably programmed computer system, and treating the new patient with the particular treatment when the model predicts efficacy of the particular treatment for the new patient.