Patent ID: 9250233
Filing Date: 2016-02-02
CPC Classification: G01N

Claim Text:
1. A method for detecting an antibody which is not complexed to an epitope of a target protein, said antibody being in a biological sample obtained from a subject which is suspected of containing such antibody, the method comprising: a) synthesizing one or more peptides having a length of about 5-15 amino acids comprising a mimetope recognized by the antibody; wherein the one or more peptides are attached directly on a solid support and wherein said mimetope comprises a linear sequence of amino acids which is different than a linear sequence of amino acids in said epitope of the target protein recognized by said antibody; b) contacting the peptide with said biological sample obtained from said subject; c) allowing binding of the one or more peptides with the antibody not complexed to an antigen to form an antibody-peptide complex; and d) detecting the antibody-peptide complex in said biological sample obtained from a subject.