Patent ID: 9507173
Filing Date: 2016-11-29
CPC Classification: B29D,C08G,C08J,C08L,C09D,G02B,G02C

Claim Text:
1. A readily-usable silicone hydrogel contact lens, comprising: a preformed silicone hydrogel contact lens; a reactive base coating on the preformed silicone hydrogel contact lens, wherein the reactive base coating comprises at least one layer of a reactive polymer having pendant carboxyl groups; and a crosslinked hydrophilic coating which is covalently attached onto the reactive base coating through neutral, hydroxyl-containing covalent linkages each of which is obtained by reacting, in a crosslinking reaction at a temperature from about 40° C. to about 140° C., between one positively-charged azetidinium group and one amino or carboxyl group, wherein the reactive polymer is polyacrylic acid, polymethacrylic acid, poly(C wherein the crosslinked hydrophilic coating is obtained from a water-soluble and thermally-crosslinkable hydrophilic polymeric material which comprises (i) from about 20% to about 95% by weight of first polymer chains derived from an epichlorohydrin-functionalized polyamine or polyamidoamine, (ii) from about 5% to about 80% by weight of hydrophilic moieties or second polymer chains derived from at least one hydrophilicity-enhancing agent having at least one reactive functional group selected from the group consisting of amino group, carboxyl group, thiol group, and combination thereof, and (iii) positively-charged azetidinium groups which are parts of the first polymer chains or pendant or terminal groups covalently attached to the first polymer chains, wherein the hydrophilic moieties or second polymer chains are covalently attached to the first polymer chains through one or more covalent linkages each formed between one azetitdinium group of the epichlorohydrin-functionalized polyamine or polyamidoamine and one amino, carboxyl or thiol group of the hydrophilicity-enhancing agent, wherein the readily-usable silicone hydrogel contact lens has (1) an averaged water contact angle of about 80 degrees or less, (2) an oxygen permeability of at least about 40 barrers, (3) an elastic modulus of about 1.5 MPa or less, and (4) a water content of from about 18% to about 70% by weight when fully hydrated.