Patent ID: 9346726
Filing Date: 2016-05-24
CPC Classification: C07B,C07C

Claim Text:
1. A process for producing a composition comprising D-mannitol crystals, of which more than 97% of the dry matter thereof consists of D-mannitol, said process comprising the steps of: producing an initial stock solution of D-mannitol in a solvent, and in the presence of an auxiliary agent, evaporating said solvent so as to carry out the crystallization of the D-mannitol, through a seeding phase and a crystal growth phase, wherein: during the seeding phase: an evaporation rate by mass of between 0.08 and 0.5 kg of solvent/h/kg of initial stock solution is applied; during the growth phase: an evaporation rate by mass of between 0.005 and 0.1 kg of solvent/h/kg of initial stock solution is applied; the evaporation rate during the seeding phase is different from the evaporation rate during the growth phase; the evaporation step is carried out with stirring and under an absolute vacuum of between 50 mbar and 100 mbar; the solvent is water; and the auxiliary agent is sorbitol.