Patent ID: 9481875
Filing Date: 2016-11-01
CPC Classification: A61K,A61P,C12N,C12Y

Claim Text:
1. A method for alleviating a PCSK9-related disorder in an individual, comprising administering to the individual a therapeutically effective amount of an immunogen, wherein the immunogen comprises an antigenic PCSK9 peptide linked to an immunogenic carrier, wherein the antigenic PCSK9 peptide consists of an amino acid sequence selected from the group consisting of SEQ ID NOs:182, 183, 184, 185, 186, 187, and 188, wherein the immunogenic carrier is selected from the group consisting of CRM197 and a virus-like particle (VLP), and wherein the PCSK9-related disorder is selected from the group consisting of an ateriosclerotic condition, a coronary artery disease, and a cardiovascular disease.