Patent ID: 9506938
Filing Date: 2016-11-29
CPC Classification: G01N

Claim Text:
1. A method for measuring inhibition of platelet reactivity by a P2Y12 antagonist in an individual treated with a drug-eluting stent (DES), comprising the steps of: a) providing a platelet containing blood sample from an individual treated with a DES and a P2Y12 antagonist; b) contacting said platelet containing blood sample with particles comprising a GPIIb/IIIa receptor ligand immobilized thereon, adenosine diphosphate (ADP) and prostaglandin E1 (PGE1) under conditions suitable for agglutination of said particles mediated by said platelet in said blood sample; and c) assessing said agglutination to determine the presence, absence and/or degree of inhibition of platelet aggregation by said P2Y12 antagonist in said individual, wherein absence or a reduction of said agglutination indicates that said individual has reduced platelet reactivity in response to said P2Y12 antagonist treatment.