Patent ID: 9393198
Filing Date: 2016-07-19
CPC Classification: A61K,A61P

Claim Text:
1. A method for ameliorating symptoms and/or treating one or more neurodegenerative diseases, in a subject comprising the steps of: identifying the subject in need of ameliorating symptoms and/or treatment against one or more neurodegenerative diseases; and administering intravenously a therapeutically effective amount of a pharmaceutical composition that ameliorates the symptoms or that treats a neurodegenerative disease comprising a curcuminoid, wherein the curcuminoid comprises curcumin dissolved or dispersed in a suitable aqueous or non-aqueous medium, wherein the curcumin is a poly-lactic-glycolic-acid (PLGA)-curcumin conjugate enclosed in one or more liposomes that cross the blood brain barrier and concentrate in the hippocampus and the striatum, the size being about 100 nanometer (nm), wherein the curcumin has been synthesized to a 99.2% purity and reaches the hippocampus at a concentration that is at least half the concentration in plasma at two hours, wherein the intravenous liposomal curcumin is administered at 20 mg/kg.