Patent ID: 9320845
Filing Date: 2016-04-26
CPC Classification: A61M,B01D,B01J

Claim Text:
1. A sorption agent for removing protein-bound substances from a biological fluid with reduced adsorption of Protein C, the sorption agent comprising: (a) a porous, neutral, hydrophobic polymer including microparticles, where the microparticles have a particle size of 20 μm or less and (b) a polypeptide layer adsorbed on the polymer, wherein the neutral, hydrophobic polymer is a styrene/divinyl benzene copolymer and has a mean pore size of 30-40 nm, wherein the polypeptide layer comprises at least one type of polypeptide selected from albumin, in particular human albumin, and albumin-like polypeptides, and wherein a 10% polypeptide solution is used for the adsorptive coating of the neutral, hydrophobic polymer with the polypeptide layer.