Patent ID: 9329188
Filing Date: 2016-05-03
CPC Classification: G01N

Claim Text:
1. A method of analyzing a population of microvesicles each having a diameter of 300 nm to 900 nm for the presence of invasive microvesicles, the method comprising: providing a biological sample comprising the population of microvesicles, wherein the population of microvesicles is suspected of comprising invasive microvesicles; determining whether ARF6 is present in the population of microvesicles each having a diameter of 300 nm to 900 nm, determining whether an other marker is present in the population of microvesicles, wherein the other marker comprises at least one of the group consisting of: a processed form of the protein MTI-MMP; Vamp3; MHC class I; β1-integrin; and β1-integrin, wherein a presence of ARF6 and the other marker in the population of microvesicles indicates the presence of invasive microvesicles.