Patent ID: 9415046
Filing Date: 2016-08-16
CPC Classification: A61K,A61P,Y02A

Claim Text:
1. A method for reducing, inhibiting or reducing the likelihood of foreign body reaction associated with an implant which produces foreign body reaction in a human patient by increasing proinflammatory cytokines by upregulating a TLR 7/TLR9/NALP3 inflammasome pathway comprising administering to said patient with said implant a pathway inhibiting effective amount of a sustained release composition consisting essentially of a salicylate compound according to the chemical structure: where R is H or a C a pharmaceutically acceptable salt thereof to said patient, wherein the sustained release administration of said salicylate compound increases the residence time of said implant in said patient by reducing inflammation and scarring associated with said implant and wherein said sustained release composition continuously releases said salicylate in effective amounts.