Patent ID: 9352070
Filing Date: 2016-05-31
CPC Classification: A61F,A61L

Claim Text:
1. A tissue prosthesis for reconstructing and replacing damaged biological structures and tissue, comprising: a seamless tubular member comprising a decellularized mammalian tubular structure, said tubular structure having a first length, proximal and distal ends, an outer surface and a lumen that extends therethrough, said tubular structure further comprising at least one coating, said coating comprising poly(glycerol sebacate) (PGS), said PGS coating being disposed on at least a portion of said tubular structure outer surface, said coated tubular structure being configured to induce modulated healing when said tubular member is disposed proximate damaged biological tissue, said modulated healing comprising modulation of inflammation of said damaged tissue, host tissue proliferation, bioremodeling of said damaged tissue, and regeneration of new tissue and tissue structures with site-specific structural and functional properties.