Patent ID: 9517253
Filing Date: 2016-12-13
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method for diminishing the loss of motor function and/or diminishing inflammation of the central nervous system in a human subject in need thereof, the method consisting of: administering to said subject an effective amount of a pharmaceutical composition consisting of a Tr1 cell population directed against at least one human multiple sclerosis-associated antigen, in combination with one or more pharmaceutically acceptable carrier, or a medicament consisting of a Tr1 cell population directed against at least one human multiple sclerosis-associated antigen, wherein said human multiple sclerosis-associated antigen is myelin basic protein, myelin associated glycoprotein, myelin oligodendrocyte protein, proteolipid protein, or a mixture thereof, and the pharmaceutical composition or medicament comprises Tr1cells autologous to the cells of the subject.