Patent ID: 9290766
Filing Date: 2016-03-22
CPC Classification: A61K,A61P,C12N,C12Q

Claim Text:
1. A synthetic, modified oligonucleotide of 10 to 30 nucleotides in length comprising at least one modification wherein the at least one modification is selected from: at least one modified sugar moiety; at least one modified internucleotide linkage; at least one modified nucleotide, and combinations thereof; wherein said oligonucleotide is an antisense compound which is at least 90% complementary to and specifically hybridizes to a natural antisense polynucleotide of an Adiponectin (ADIPOQ) polynucleotide selected from the group consisting of SEQ ID NOS: 3 to 6 and upregulates the function and/for expression of an Adiponectin (ADIPOQ) having SEQ ID NOS: 1 or 2 in vivo or in vitro as compared to a normal control.