Patent ID: 9255296
Filing Date: 2016-02-09
CPC Classification: A23K,C12Q,G01N

Claim Text:
1. A method of diagnosing the existence of a kidney disorder in a feline comprising measuring the level of expression of one or more biomarkers selected from the group consisting of lumican; collagen alpha 1(III) chain, variant 12; decorin; secreted frizzled-related protein 2; retinol binding protein 5; MMP-2; MMP-7; and MMP-19, in a biological sample from the feline, comparing the level of expression of the one or more biomarkers in the biological sample from the feline to a control value, and diagnosing the existence of the kidney disorder in the feline, wherein differences in expression of the one or more biomarkers in the sample relative to the control value for expression in a sample from a normal animal indicate the existence of a kidney disorder, wherein the level of expression of the one or more biomarkers is determined by measuring gene expression of the one or more biomarkers using a DNA microarray comprising one or more oligonucleotides complementary to mRNA or cDNA corresponding to the one or more biomarkers to be measured, and wherein the oligonucleotides in the DNA microarray comprise one or more probes comprising sequences selected from one or more of SEQ ID NOS. 1-8.