Patent ID: 9428749
Filing Date: 2016-08-30
CPC Classification: A61P,C12N

Claim Text:
1. A method of treating obesity, hypercholesterolemia, type 2 diabetes, hepatic steatosis, hyperlipidemia, insulin resistance, a glycogen storage disease, or aberrant glucose uptake and/or utilization in a subject in need thereof comprising administering to the subject an inhibitor of miR-208a and/or miR-208b, wherein the inhibitor is an antisense oligonucleotide, wherein the antisense oligonucleotide comprises a sequence that is at least partially complementary to a mature sequence of miR-208a and/or miR-208b, and wherein the expression or activity of miR-208a and/or miR-208b is reduced in the cells of the subject following administration.