Patent ID: 9403847
Filing Date: 2016-08-02
CPC Classification: A61P,C07D

Claim Text:
1. A method of treating a disease selected from breast cancer, prostate cancer, colon cancer, brain cancer, bladder cancer, skin cancer, cancer of the uterus, ovary cancer, lung cancer, pancreatic cancer, renal cancer, gastric cancer, acute myeloblastic leukemia, chronic myeloid leukemia, and B cell lymphoma, in a patient, comprising administering to said patient a therapeutically effective amount of a compound of Formula I: or a pharmaceutically acceptable salt thereof; wherein: the symbol Z is O, S, or NR U is N; and V is C; or U is C; and V is N; X is N or CR X is absent; and Y is S or O; Ar is a purine ring, substituted with n independently selected R Cy is cycloalkyl, heterocycloalkyl, aryl or heteroaryl, each substituted with m independently selected R R each R each R R each R or any R R each Cy each R or any R each R each R or any R each R or any R r is 0 or 1; wherein treating refers to inhibiting or ameliorating the disease.