Patent ID: 9435813
Filing Date: 2016-09-06
CPC Classification: G01N

Claim Text:
1. A method of predicting and improving prognosis of a subject suffering from hemorrhagic shock (HS), the method comprising: obtaining a sample comprising serum from the subject; determining expression levels of keratinocyte chemoattractant (KC)/human growth-regulated oncogene (GRO) (KC/GRO), zona pellucida sperm-binding protein 1 (ZP1), and apolipoprotein A2 (APOA2) in the sample to obtain test values; comparing the test values to respective reference values that represent threshold levels of KC/GRO, ZP1, and APOA2; identifying the subject as having an increased risk of mortality due to HS if the test values are above the reference values, or identifying the subject as having an increased chance of survival if the test values are below the reference values, and administering an effective amount of a vasopressor to the subject identified as having an increased risk of mortality due to HS, thereby improving prognosis of the subject.