Patent ID: 9475838
Filing Date: 2016-10-25
CPC Classification: A61K,C07K,C12N,Y02A

Claim Text:
1. A process for purification of a recombinant Sm14 Schistosoma mansoni protein, said process comprising the steps of: (a) performing lysis of cells containing the Sm14 protein to obtain a lysate; (b) clarifying the lysate obtained in step (a) to obtain a clarified lysate; (c) loading the clarified lysate in a column containing an anion exchange resin; (d) eluting proteins from the column by pH changes in the column; and (e) separating contaminant proteins from the Sm14 protein by gel-filtration, wherein said Sm14 protein is encoded by SEQ ID NO:3 and is expressed in