Patent ID: 9297045
Filing Date: 2016-03-29
CPC Classification: A61P,C12Q

Claim Text:
1. A method of selecting a treatment for a patient suffering from lung cancer, the method comprising the steps of: a) providing a test sample from the patient wherein treatment with a chemotherapy agent is at least one treatment option for the patient; b) determining a copy number for a marker in the test sample by fluorescent in situ hybridization, wherein the marker comprises cyclin E1 and ZNF536 genes; c) comparing the copy number of the marker in the test sample against a normal copy number of the marker, wherein the normal copy number of the marker is two, thereby determining the presence or absence of a copy number gain for the marker in the test sample, and d) selecting a chemotherapy treatment regimen based on the comparison in step c) and e) administering adjuvant chemotherapy post-surgery when the comparison in step (c) indicates the subject has a decreased overall survival time, wherein the lung cancer is Stage I-II non-small-cell lung cancer.