Patent ID: 9458500
Filing Date: 2016-10-04
CPC Classification: C12Q,G01N

Claim Text:
1. An apparatus for DNA sequencing comprising: a) at least one reaction chamber including a DNA primer/template system which produces a detectable reaction event when a DNA polymerase enzyme incorporates an unlabeled and unblocked deoxyribonucleotide monophosphate onto the 3′ end of the primer strand; b) a component for introducing into, and evacuating from, said reaction chamber at least one reagent selected from the group consisting of: buffers, electrolytes, DNA template, DNA primer, unlabeled and unblocked deoxyribonucleotides, and polymerase enzymes; c) a system for converting said detectable reaction event into an electrical signal based on an electrical potential generated from said detectable reaction event in the at least one reaction chamber; and d) a voltmeter configured to measure said electrical signal in the at least one reaction chamber.