Patent ID: 9482664
Filing Date: 2016-11-01
CPC Classification: A61B,G01N

Claim Text:
1. A device comprising: a. a substrate comprising a surface; b. a non-fouling polymer layer on the surface, wherein the non-fouling polymer layer comprises a plurality of brush molecules; c. at least one capture region on the polymer layer, comprising at least one capture agent non-covalently bound to the polymer layer, wherein the at least one capture agent binds a target in a sample and the at least one capture agent remains bound to the polymer layer when exposed to the sample; and d. at least one labile region on the polymer layer, comprising at least one detection agent and an excipient, wherein the at least one detection agent solubilizes upon contact with the sample and labels the target in the sample; wherein the capture region and the labile region are spatially separated.