Patent ID: 9470651
Filing Date: 2016-10-18
CPC Classification: C12Q,G01N

Claim Text:
1. An apparatus comprising: a substrate securing a channel located along a surface of the substrate, the channel having an effective width that is not limited by the Debye screening length; at least one reservoir configured for containing and presenting a sample having bio-molecules for delivery in the channel; a first electrode and a second electrode, each of the electrodes configured for electrically coupling a charge in the sample to enhance ionic current flow therein; at least one sense electrode structure including one buried electrode to detect charges of the bio-molecules that are electrically driven along surfaces of the channel and located along the channel, and configured for sensing a characteristic of the sample at least partly based on electrostatic interaction between the enhanced ionic current flow of the sample and the at least one sense electrode structure; and a charge-signal circuit coupled to the at least one sense electrode structure, and configured for processing a signal carried therefrom and providing an output useful for identifying a type of the bio-molecules delivered in the channel.