Patent ID: 9340615
Filing Date: 2016-05-17
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An antibody that recognizes fibronectin type III domain 1 (FND1) of anexelekto (AXL), which is an antibody of any one of (1) to (3) below: (1) an antibody comprising a heavy chain variable region comprising a CDR1 comprising the amino acid sequence of any one of SEQ ID NOs: 33 to 37, a CDR2 comprising the amino acid sequence of any one of SEQ ID NOs: 38 to 48, and a CDR3 comprising the amino acid sequence of SEQ ID NO: 49; and a light chain variable region comprising a CDR1 comprising the amino acid sequence of any one of SEQ ID NOs: 84 to 89, a CDR2 comprising the amino acid sequence of SEQ ID NO: 90, and a CDR3 comprising the amino acid sequence of SEQ ID NO: 91; wherein the amino acid sequence of the heavy chain variable region comprises at least one of the following amino acid residues: (2) an antibody comprising a heavy chain variable region of SEQ ID NO: 2 (H0); and (3) an antibody comprising a light chain variable region of SEQ ID NO: 65 (L0).