Patent ID: 9528106
Filing Date: 2016-12-27
CPC Classification: C12N,C12Q

Claim Text:
1. A method for isolating one or more genetic elements encoding a gene product having a desired catalytic activity, comprising the steps of: (a) compartmentalising the genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; and (c) sorting the genetic elements which produce gene product(s) having the desired catalytic activity, wherein the desired catalytic activity of the gene product results, directly or indirectly, in the enzymatic modification of the genetic element encoding the gene product or the microcapsule containing it to enable the isolation of the genetic element, and wherein the gene product having the desired catalytic activity induces a change in the microcapsule which, when detected, triggers the modification of the genetic element within the compartment to enable the isolation of the genetic element.