Patent ID: 9422231
Filing Date: 2016-08-23
CPC Classification: A61K,C07C,Y02A

Claim Text:
1. A method selected from the group consisting of: (a) a method of inhibiting proliferation of wherein X is alkoxy (cyclic or alicyclic) or aryloxy, and Q represents the imido-substitutent bonded to the 1,4-naphthoquinone moiety through the imido nitrogen, (b) a method of inhibiting tubulin polymerization in wherein X is alkoxy (cyclic or alicyclic) or aryloxy, and Q represents the imido-substitutent bonded to the 1,4-naphthoquinone moiety through the imido nitrogen, (c) a method of treating Chagas disease in a patient in need of treatment comprises administering to said patient a therapeutically effective amount of an imido-substituted 1,4-naphthoquinone represented by the general formula: wherein X is alkoxy (cyclic or alicyclic) or aryloxy, and Q represents the imido-substitutent bonded to the 1,4-naphthoquinone moiety through the imido nitrogen, and (d) a method of inhibiting proliferation of wherein X is alkoxy (cyclic or alicyclic) or aryloxy, and Q represents the imido-substitutent bonded to the 1,4-naphthoquinone moiety through the imido nitrogen, wherein Q is represented by the formula: wherein in Q each R is, independently, a substituted or unsubstituted hydrocarbon, provided that one R can, optionally, be hydrogen, and provided that, optionally, R can include at least one hetero atom.