Patent ID: 9241885
Filing Date: 2016-01-26
CPC Classification: A61K,A61P,A61Q

Claim Text:
1. An oral care mouthrinse composition comprising: (a) from about 324 ppm or greater than 324 ppm bioavailable amount of cetylpyridinium chloride as essential antimicrobial active and (b) a pharmaceutically-acceptable liquid carrier comprising a major proportion of water, from about 5% to about 30% by weight of the composition of glycerin as humectant, from about 0.01% to about 10% of a sweetening agent selected from sucrose, glucose, saccharin, dextrose, levulose, lactose, mannitol, sorbitol, fructose, maltose, thaumatin, aspartame, D-tryptophan, dihydrochalcones, acesulfame, cyclamate and salts thereof and from about 0.04% to about 2% of a flavoring agent selected from oil of wintergreen, oil of spearmint, clove bud oil, menthol, anethole, methyl salicylate, eucalyptol, cassia, 1-menthyl acetate, sage, eugenol, parsley oil, oxanone, alpha-irisone, marjoram, lemon, orange, propenyl guaethol, cinnamon, vanillin, thymol, linalool, cinnamaldehyde glycerol acetal known as CGA, wherein the composition is essentially free of anionic, nonionic or amphoteric surfactants, glycol solvents and anti-staining additives and free of excipients having a negative effect on bioavailability of the quaternary ammonium agents; and wherein the composition has at least 65% bioavailability as determined by a Disk Retention Assay to deliver a bioavailable level of quaternary ammonium antimicrobial agent required for efficacy, has no more than 5% ethyl alcohol for improved taste and suitability for safe use by consumers, and has an aesthetically acceptable clear appearance and is antibiotic free.