Patent ID: 9488663
Filing Date: 2016-11-08
CPC Classification: C12Q,G01N

Claim Text:
1. A device configured to perform an immunoassay for a target analyte in a urine sample, the device comprising: a first region comprising reagents configured to amend the urine sample to remove or reduce a urea concentration in the urine sample below a preselected urea threshold, wherein the reagents comprise urease and a buffer; and a second region comprising at least one electrode coated with a biolayer comprising an attached capture antibody configured to bind to the target analyte, which is different from that of the urea, wherein the second region is configured to determine a concentration of the target analyte in the amended urine sample, wherein the first region is configured to provide a dissolved urease enzymatic activity within the amended urine sample in a range of about 10 to 10,000 IU/mL.