Patent ID: 9402922
Filing Date: 2016-08-02
CPC Classification: A61B,A61K,A61M

Claim Text:
1. A method of endoscopic diagnostic evaluation of pathologies of the small intestine and/or the large intestine in a subject, said method comprises administering to the subject a diagnostically effective amount of at least one solid composition within a 24 hour period preceding the endoscopic diagnostic evaluation and endoscopic diagnostically evaluating the small intestine and/or the large intestine for said pathologies, said solid composition comprising: (a) at least one dye selected from among methylene blue, congo red, carmine indigo, toluidine blue or mixtures thereof; (b) a first matrix in which said at least one dye is incorporated, wherein said first matrix comprises at least one lipophilic compound having a melting point below 90° C. and at least one amphiphilic compound, wherein said at least one amphiphilic compound is selected from among polar lipids of type I or II, ceramides, glycol alkyl ethers, or alkyl sulfosuccinate salts and wherein said polar lipids of type I or II are selected from among lecithin, phosphatidylcholine, phosphatidylethanolamine or mixtures thereof, and said glycol alkyl ether is diethylene glycol monomethyl ether; (c) a second matrix comprising at least one hydrophilic compound, wherein the first matrix is dispersed in the second matrix; (d) optionally other physiologically acceptable excipients; and (e) optionally a gastro-resistant coating.