Patent ID: 9418416
Filing Date: 2016-08-16
CPC Classification: G01N,G06T

Claim Text:
1. A method of nondestructive counting and sizing of undissolved particles in a vessel that is at least partially filled with a fluid, the method comprising: (a) receiving, by a sensor of an imaging system, at least one image of the particles in the vessel obtained under specified imaging conditions; and analyzing the at least one image by a processor of the imaging system, the analyzing including (b)-(d): (b) detecting the particles and determining information indicative of an apparent size of the detected particles in the image; (c) determining apparent particle size population information indicative of an apparent particle size distribution of the detected particles; and (d) determining actual particle size population information indicative of an actual particle size distribution of the detected particles based on: wherein (d) comprises fitting a superposition of apparent size distributions for a plurality of the sets of standard sized particles to the apparent particle size population of the detected particles; and wherein fitting the superposition of apparent size distributions for the plurality of sets of standard sized particles conditions to the apparent particle size population of the detected particles comprises: minimizing a difference between the superposition and the apparent particle size population of the detected particles by adjusting the weighting of the apparent size distributions for the plurality of sets of standard sized particles.