Patent ID: 9353418
Filing Date: 2016-05-31
CPC Classification: A61P,C12Q

Claim Text:
1. A composition comprising an isolated pair of polynucleotide primers comprising at least 10 but less than 600 contiguous nucleotide residues of a coding sequence of a human IDH1 or IDH2 protein found in a human tumor or its complement, wherein at least one of said primers is labeled with a detectable label, wherein in one of said pair of polynucleotide primers said at least 10 contiguous nucleic acid residues comprise: nucleotides 394 and/or 395 of IDH1 coding sequence, wherein said nucleotides are not C or T at nucleotide 394 and/or not G at nucleotide 395, respectively; nucleotide 515 of IDH2 coding sequence, wherein said nucleotide 515 is not a G; the complement of nucleotides 394 and/or 395 of IDH1 coding sequence, wherein said nucleotides are not G or A at the complement of nucleotide 394 and/or not C at the complement of nucleotide 395, respectively; or the complement of nucleotide 515 of IDH2 coding sequence, wherein said complement of nucleotide 515 is not a C.