Patent ID: 9504671
Filing Date: 2016-11-29
CPC Classification: A61K,A61P

Claim Text:
1. A pharmaceutical composition for topical administration to a mammal comprising two or more pharmaceutically acceptable excipients and a therapeutically effective amount of a spiro-oxindole compound having the following formula: or a pharmaceutically acceptable salt thereof, wherein each pharmaceutically acceptable excipient is present in a concentration of from about 0.01% w/w to about 99% w/w, wherein the pharmaceutically acceptable excipients are selected from one or more solvents, one or more penetration enhancing agents, one or more stiffening agents, one or more ointment bases and, optionally, one or more antioxidants, and wherein a solvent is selected from PEG 400 or PEG 3350, a penetration enhancing agent is selected from diethylene glycol monoethyl ether, oleyl alcohol, or isopropyl myristate, a stiffening agent is stearyl alcohol, an ointment base is selected from PEG 400 or PEG 3350, and the antioxidant, if present, is butylated hydroxytoluene (BHT).