Patent ID: 9399093
Filing Date: 2016-07-26
CPC Classification: A61M,B04B

Claim Text:
1. An online extracorporeal photopheresis system comprising: (a) a disposable fluid circuit comprising: (b) a freestanding separation device having said processing chamber received therein for effecting separation of said mononuclear cells from whole blood, (c) a freestanding irradiation device independent of, and spaced apart and housed separately from, said separation device and having said mononuclear cell storage container received therein simultaneously with the processing chamber being received in the separation device for treating said mononuclear cells with a selected dose of light, (d) a controller separate from the separation device and the irradiation device for communicating with and controlling both devices, the controller configured to i. dilute the mononuclear cells received in the storage container with a diluting solution comprising saline or plasma prior to activation of the irradiation device, ii. concentrate the irradiated diluted mononuclear cells by separating supernatant liquid, iii. combine the concentrated mononuclear cells with a wash solution, and iv. separate the combination into a concentrated washed cell product and supernatant liquid, (e) wherein said disposable fluid circuit provides a sterile closed pathway between said processing chamber when mounted in said separation device and said storage container when mounted in said irradiation device.