Patent ID: 9347917
Filing Date: 2016-05-24
CPC Classification: G01N,H01J

Claim Text:
1. A method for mass analysis comprising: generating ions of an analyte using an ion source; selecting a subset of ions received from the ion source with a mass filter that is coupled in an ion flow path; transmitting the subset of ions through a reaction region that is coupled in an ion flow path with the mass filter and that is filled with any of an inert gas that is used to induce collision-induced dissociation of ions received from the mass filter and ozone that is used to induce ozone-induced dissociation of such ions; detecting the subset of ions using an ion analyzer that is coupled in an ion flow path with the reaction region and that separates any of ions and fragments received from the reaction region as a function of mass-to-charge ratio (m/z) and that generates an output representing a spectrum thereof; and employing the ion source, mass filter, reaction region and ion analyzer to identify the location of carbon-carbon double bonds, if any, in the analyte by (1) subjecting ions of the analyte generated by the ion source to mass analysis without any fragmentation or reaction, (2) subjecting ions of the analyte generated by the ion source to collision-induced dissociation in the reaction region, (3) determining relationships between masses and/or mass-to-charge ratios of the ions and/or fragments produced by such collision-induced dissociation, (4) selectively subjecting, based on those relationships, ions generated by the ion source to ozone-induced dissociation in the reaction region, and (5) determining the location(s) of carbon-carbon double bonds, if any, from reaction products of such ozone-induced dissociation.