Patent ID: 9382326
Filing Date: 2016-07-05
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An isolated antibody or antigen-binding portion thereof comprising: (a) an HCDR1 comprising an amino acid sequence of SEQ ID NO: 3; (b) an HCDR2 comprising an amino acid sequence with amino acid substitutions at the 9 (c) an HCDR3 comprising an amino acid sequence with amino acid substitutions at the 2 (d) an LCDR1 comprising an amino acid sequence with amino acid substitutions at the 5 (e) an LCDR2 comprising an amino acid sequence of SEQ ID NO: 31;and (f) an LCDR3 comprising an amino acid sequence with amino acid substitutions at the 3 and wherein said antibody or antigen-binding portion thereof binds to the BAFFR polypeptide with a K