Patent ID: 9522932
Filing Date: 2016-12-20
CPC Classification: A61P,C07F,C07H

Claim Text:
1. A process for preparing a compound represented by any one of the general formulae (XXVII) to (XXX): wherein: U is an acyl group, and V is a silyl group, or a pharmaceutically acceptable salt thereof, the process comprising the initial step of reacting a 2,3-dihydroxy-dihydro-furan-1-one with a silylating agent comprising a group V to produce the compound XXVII; further comprising acylation of the free hydroxyl group of compound XXVII to produce compound XXVIII; further comprising reduction of the lactone carbonyl of compound XXVIII to produce an intermediate hemi-acetal; further comprising silylation of the intermediate hemiacetal hydroxyl group to produce compound XXIX; and lastly further comprising de-acylation of compound XXIX to produce compound XXX.