Patent ID: 9345250
Filing Date: 2016-05-24
CPC Classification: A23D,A23L,A61K,A61Q

Claim Text:
1. A method for preparing a solubilized semi-solid or paste composition containing an oil-soluble substance having both acid and heat resistance, comprising: a step of dissolving the oil-soluble substance and a combination of two or three emulsifiers selected from the group consisting of: (1) one emulsifier E1 and one emulsifier E2; (2) one emulsifier E1 and one emulsifier E3; (3) one emulsifier E2 and one emulsifier E3; and (4) one emulsifier E1, one emulsifier E2 and one emulsifier E3, in a solvent which is (a) ethanol or (b) a mixed solvent of ethanol with at least one other solvent selected from the group consisting of acetone, hexane and ethyl acetate, to prepare a transparent solution; and a step of distilling the solvent off of the transparent solution, wherein: the emulsifier E1 is one or more selected from the group consisting of: (E1-1) decaglycerol monomyristate; (E1-2) decaglycerol monolaurate; (E1-3) tetraglycerol monolaurate; (E1-4) decaglycerol monocaprate; and (E1-5) hexaglycerol monolaurate, the emulsifier E2, in which monoesters account for 50% or more, is: (E2-1) sucrose myristate; and/or (E2-2) sucrose laurate, and the emulsifier E3 is one or more selected from the group consisting of: (E3-1) soybean fractionated lecithin; (E3-2) soybean fractionated lysolecithin; (E3-3) rapeseed fractionated lecithin; (E3-4) rapeseed fractionated lysolecithin; (E3-5) sunflower fractionated lecithin; and (E3-6) sunflower fractionated lysolecithin, wherein the fractionated lecithin(s) contain not less than 50% of phosphatidylcholine relative to a phospholipid content, and wherein the fractionated lecithin(s) are obtained by a method comprising the steps of degumming in production of a vegetable oil to obtain a vegetable lecithin, treating the vegetable lecithin with acetone to obtain an acetone-insoluble fraction, treating the acetone-insoluble fraction with ethanol to obtain an ethanol-soluble fraction, and evaporating ethanol from the ethanol-soluble fraction, wherein the fractionated lysolecithin(s) contain not less than 50% of lysophosphatidylcholine relative to a phospholipid content, and wherein the fractionated lysolecithin(s) are obtained by a method comprising a step of enzymatically decomposing vegetable lecithin containing phosphatidylcoline in an amount ≧50% with a phospholipase A1 or A2 or a step of enzymatically decomposing a vegetable lecithin to obtain an ethanol-soluble fraction, and wherein the contents of the combination of two or three emulsifiers to 1 part by mass of the oil-soluble substance are: for (1), 0.1 to 50 parts by mass for the emulsifier E1, and for (2), 0.1 to 50 parts by mass for the emulsifier E1, and for (3), 0.1 to 30 parts by mass for the emulsifier E2, and for (4), 0.1 to 50 parts by mass for the emulsifier E1, to obtain the solubilized semi-solid or paste composition.