Patent ID: 9399217
Filing Date: 2016-07-26
CPC Classification: B01L,B03C,C12Q,C40B,G01N,H01L

Claim Text:
1. A system for sensing a biological reaction in a solution, comprising: a bead in said solution bound or attached to at least one biological reactant, wherein said biological reactant comprises a nucleic acid template; a pair of electrodes in contact with said solution and positioned such that, during sensing by said pair of electrodes, said pair of electrodes are each within the Debye layer of said bead when said bead is immobilized in proximity to said pair of electrodes; a bead capture feature that immobilizes said bead in proximity to said pair of electrodes; and a device that (i) receives electrical signals from said pair of electrodes when said pair of electrodes is within the Debye layer of said bead, and (ii) using said electrical signals, determines change(s) in impedance resulting from a biological reaction with said nucleic acid template.