Patent ID: 9265753
Filing Date: 2016-02-23
CPC Classification: A61K,A61P

Claim Text:
1. A method of minimizing the burning sensation associated with oral mucosal administration of alpha lipoic acid (ALA), comprising: providing a hard candy lozenge comprising a therapeutically effective amount of ALA dispersed in a release limiting matrix, administering the lozenge comprising placing the lozenge into the oral cavity of an individual and permitting the lozenge to remain intact in the oral cavity for a sufficient period of time for the lozenge to dissolve completely, wherein the lozenge has an ALA release rate which is less than the release rate of a small scale lozenge weighing 3 grams and made by (1) heating a matrix consisting of 185 grams of sugar, 148 grams of light corn syrup, 64 grams of water, 1.3 grams of red food coloring, 2.7 grams of cinnamon oil and 6% by mass ALA to 300° F., (2) pouring the matrix into a hard candy mold and (3) cooling completely.