Patent ID: 9409989
Filing Date: 2016-08-09
CPC Classification: A61K,C07K,Y10S

Claim Text:
1. A method of preparing a multispecific antibody comprising culturing a host cell expressing a multispecific antibody, and recovering the multispecific antibody from the culture, wherein said multispecific antibody comprises four polypeptides, wherein a first and a second of said polypeptides each comprise a heavy chain constant domain and a heavy chain variable domain, and a third and a fourth of said polypeptides are each common light chains that are identical to each other, wherein said first polypeptide and said third polypeptide form a binding domain that binds a first antigen, and wherein said second polypeptide and said fourth polypeptide form a binding domain that binds a different antigen, and wherein said first polypeptide and said second polypeptide dimerize to form a multispecific antibody, wherein the multispecific antibody is an IgG, IgE or IgD antibody.