Patent ID: 9458240
Filing Date: 2016-10-04
CPC Classification: A61K,C07K

Claim Text:
1. A lyophilized formulation prepared by lyophilizing an aqueous formulation having a pH of 6.5 and comprising (i) a hypofucosylated or non-fucosylated anti-BAFF Receptor (anti-BAFFR) antibody wherein the antibody has a concentration of 50 mg/ml, and wherein said anti-BAFFR antibody comprises heavy chain CDR1, CDR2 and CDR3 comprising amino acid sequences of SEQ ID NOs: 3, 4 and 5 respectively, and light chain CDR1, CDR2 and CDR3 comprising amino acid sequences of SEQ ID NOs: 6, 7 and 8, (ii) 90 mM sucrose as a stabilizer, (iii) 7 mM histidine as a buffering agent, (iv) 0.02% polysorbate 80 as a surfactant, and (v) 17 mM arginine-HCl.