Patent ID: 9320728
Filing Date: 2016-04-26
CPC Classification: A61K,A61P

Claim Text:
1. A method for producing a patch comprising a support layer and an adhesive agent layer arranged on at least one surface of the support layer, the method comprising: A) obtaining an adhesive agent layer composition comprising B) heating the adhesive agent layer composition at a temperature in a range from 50 to 70° C. for 5 minutes to 24 hours; and C) cooling the heated adhesive agent layer composition to a normal temperature ranging from 3 to 30° C. at an average rate of temperature drop of 1 to 20° C./hour, thereby obtaining the adhesive agent layer comprising the free ropinirole at a supersaturated concentration in a dissolved form, wherein no precipitation of free ropinirole crystals occur within 24 months in the obtained adhesive agent layer at a temperature of 25° C.