Patent ID: 9387152
Filing Date: 2016-07-12
CPC Classification: A61J,A61K,A61P,C12Y

Claim Text:
1. A method of encapsulating a blood substitute composition, the method comprising the steps of: a. mixing a lipid preparation with a composition comprising an oxido-reductase enzyme, a dismutase, a catalase, a reducing agent, and an electron acceptor; b. extruding the mixture to form lipid vesicles; and c. isolating lipid vesicles, wherein the lipid preparation comprises at least one lipid selected from the group consisting of: DPPC, DSPC, DOPC, DLPC, DPPG, DSPG, DHPG, DOPG, DSPEG PEG 5000, DSPE-PEG200, and DOPE-PEG5000, and, wherein electron acceptors include but are not limited to: methylene blue, sodium 2,6-dibromophenol-indophenol, sodium 2,6-dichlorophenol-indophenol, sodium o-cresol indophenols, indigotetrasulfonic acid, indigotrisulfonic acid, indigo carmine, indigomono sulfonic acid, phenosafranin, safranin T, neutral red, and thionine.