Patent ID: 9512429
Filing Date: 2016-12-06
CPC Classification: C12N

Claim Text:
1. A conditionally replicating viral vector, comprising an inhibitory RNA molecule comprising an oligonucleotide that knocks down expression of NanogP8 wherein the oligonucleotide comprises a sequence selected from the group consisting of SEQ ID NO:3 (5′-GAGGCAGCAGAGACCGCTGCATGCACTTCCAGCCA-3′); SEQ ID NO:37 (5′-GAGGCAGCAGAGACCGCTGCATGCAGTTCCAGCCG-3′); SEQ ID NO:8 (5′-TCTGACAGGAAGTGGCTGGAAGTGCATGCAG-3′) and SEQ ID NO:34 (5′-TCTGACAGGAAGTGGCTGGAACTGCATGCAG-3′).