Patent ID: 9441267
Filing Date: 2016-09-13
CPC Classification: C12Q

Claim Text:
1. A method of detecting a plurality of target deoxyribonucleic acids, comprising: a) providing a plurality of target deoxyribonucleic acids; b) hybridizing a plurality of first primers to first portions of each of said plurality of target deoxyribonucleic acids, wherein each of said first primers comprises an adapter sequence exogenous to sequences of said target deoxyribonucleic acids, wherein said plurality of first primers are different from each other; c) hybridizing a plurality of second primers to second portions of each of said plurality of target deoxyribonucleic acids, wherein said plurality of second primers are different from each other; d) extending said first or said second primers, and then ligating said first and second primers together to form a plurality of modified primers comprising said adapter sequences; e) hybridizing said adapter sequences of said modified primers to an array of capture probes attached to a solid support, thereby forming hybridized capture probes; f) modifying said hybridized capture probes by polymerase extension to form modified capture probes, and g) detecting said modified capture probes, thereby detecting said plurality of target deoxyribonucleic acids, wherein unextended first or second primers are removed from said modified primers prior to (e).