Patent ID: 9512190
Filing Date: 2016-12-06
CPC Classification: A61K,A61P,C07K,C12N,Y02A

Claim Text:
1. A Chikungunya virus (CHIKV) or Venezuelan equine encephalitis virus (VEEV) virus-like particle, wherein said virus-like particle contains at least one malaria antigen inserted into an E2 envelope protein to form a fusion protein, wherein said at least one malaria antigen is inserted within a CHIKV E2 envelope protein at a site that corresponds in position to a site between residues 509-512, the site between residues 519-520, the site between residues 529-530, or the site between residues 531-532 of SEQ ID NO: 1 or 2; or wherein said at least one antigen is inserted within a VEEV E2 envelope protein at a site that corresponds in position to a site between residues 515-520, or a site between residues 536-539 of SEQ ID NO: 3, and wherein said at least one malaria antigen is selected from the group consisting of (a) and (b): (a) (NPNA) (b) (EYLNKIQ