Patent ID: 9452144
Filing Date: 2016-09-27
CPC Classification: A61K,A61L,A61P

Claim Text:
1. A method for applying a coating to an anatomical site on tissue of a living organism comprising the steps of: a) applying to the site an anhydrous fibrous sheet comprising a first component of fibrous polymer containing electrophilic or nucleophilic groups; b) applying to the site an aqueous solution or dispersion comprising a second component capable of crosslinking the first component, wherein the second component contains electrophilic groups if the first component contains nucleophilic groups or contains nucleophilic groups if the first component contains electrophilic groups; and c) allowing the first and the second component to crosslink on the site to form a hydrogel that is adhesive to the tissue, wherein the fibrous polymer comprises at least one oxidized polysaccharide having aldehyde groups and the second component comprises at least one water-dispersible multi-arm polyether amine.