Patent ID: 9439982
Filing Date: 2016-09-13
CPC Classification: A61K,C07D

Claim Text:
1. A compound having the following formula (I): wherein: R1, R2, R3, n, m, a, b, c, d, e and X are defined such that the compound of formula (I) is chosen from: 1) 1-(6-(3-(4-(3-aminopropylamino)butylamino)propylamino)-6-oxohexyl) 2-((1E,3E,5E)-5-(1-methyl-3,3-dimethylindolin-2-ylidene)penta-1,3-dienyl)-3,3-dimethyl-3H-indolium iodide, 2) 1-{5-[4-(3-aminopropylamino)-butylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E)-5-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-penta-1,3-dienyl}-3H-indolium iodide, 3) 1-{5-[3-(4-aminobutylamino)-propylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E)-5-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-penta-1,3-dienyl}-3H-indolium iodide, 4) 1-{5-[4-amino-butylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E)-5-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-penta-1,3-dienyl}-3H-indolium iodide, 5) 1-(6-(3-(4-(3-aminopropylamino)butylamino)propylamino)-6-oxohexyl)2-((1E,3E,5E)-5-(1-butyl-3,3-dimethylindolin-2-ylidene)penta-1,3-dienyl)-3,3-dimethyl-3H-indolium bromide, 6) 1-{5-[4-(3-aminopropylamino)-butylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E)-5-[1-butyl-3,3-dimethyl-1,3-dihydroindol-(2E)-ylidene]-penta-1,3-dienyl}-3H-indolium bromide, 7) 1-(5-{3-[4-(3-aminopropylamino)butylamino]-propylcarbamoyl}-pentyl)-2-{(1E,3E,5E)-7-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3,3-dimethyl-3H-indolium iodide, 8) 1-{5-[4-(3-aminopropylamino)-butylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E,5E)-7-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3H-indolium iodide, 9) 1-{5-[3-(4-aminobutylamino)-propylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E,5E)-7-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3H-indolium iodide, 10) 1-[5-(4-aminobutylamino)-pentyl]-3,3-dimethyl-2-{(1E,3E,5E)-7-[1,3,3-trimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3H-indolium iodide, 11) 1-(5-{3-[4-(3-aminopropylamino)butylamino]-propylcarbamoyl}-pentyl)-2-{(1E,3E,5E)-7-[1-butyl-3,3-dimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3,3-dimethyl-3H-indolium bromide, 12) 1-{5-[4-(3-aminopropylamino)-butylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E,5E)-7-[1-butyl-3,3-dimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3H-indolium bromide, 13) 1-{5-[3-(4-aminobutylamino)-propylcarbamoyl]-pentyl}-3,3-dimethyl-2-{(1E,3E,5E)-7-[1-butyl-3,3-dimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3H-indolium bromide, and 14) 1-[5-(4-aminobutylcarbamoyl)-pentyl]-2-{(1E,3E,5E)-7-[1-butyl-3,3-dimethyl-1,3-dihydroindol-(2E)-ylidene]-hepta-1,3,5-trienyl}-3,3-dimethyl-3H-indolium bromide, or a pharmaceutically acceptable salt thereof.