Patent ID: 9259473
Filing Date: 2016-02-16
CPC Classification: A61K,A61L,C08J

Claim Text:
1. A hydrogel obtained by covalently cross-linking a first macromonomer comprising an N-Hydroxysuccinimide (NHS) ester group with a second macromonomer comprising a N-terminal cysteine group, wherein covalently cross-linking the first and second macromonomers comprises: (a) forming an amide bond between the carboxyl carbon of the N-Hydroxysuccinimide (NHS) ester group of the first macromonomer and the primary amine of the N-terminal cysteine group of the second macromonomer to form a third macromonomer, and (b) forming a disulfide bond between primary thiol groups on two of the third macromonomers produced in step (a).