Patent ID: 9238816
Filing Date: 2016-01-19
CPC Classification: C12N,G01N

Claim Text:
1. An aptamer having a G-quartet structure and being at least one selected from the group consisting of the following polynucleotides, the aptamer having a binding ability to an amyloid protein oligomer: (1) a polynucleotide comprising a base sequence represented by any one of SEQ ID NO:1 to SEQ ID NO:18; (2) a polynucleotide of 20-30 nucleotides in length and comprising a base sequence that includes at least four sets of at least two consecutive guanosine nucleotides and in which one or 2-5 bases have been deleted, substituted, or added in a base sequence represented by any one of SEQ ID NO:1 to SEQ ID NO:18; and (3) a polynucleotide that is a multimer including the polynucleotide of (1) or (2) as a structural unit.