Patent ID: 9365846
Filing Date: 2016-06-14
CPC Classification: C07K,C12N,C40B

Claim Text:
1. An antibody display system comprising an isolated host cell wherein the host cell is selected from the group consisting of a Pichia cell, a Chinese hamster ovary (CHO) cell and a Saccharomyces cerevisiae cell; wherein said isolated host cell comprises (a) a polynucleotide encoding a bait comprising a heavy Fc immunoglobulin domain fused to a surface anchor polypeptide operably associated with a regulatable promotor; (b) one or more polynucleotides encoding an immunoglobulin light chain variable region; and (c) one or more polynucleotides encoding an immunoglobulin heavy chain variable region wherein the heavy chain is VH—CH1-CH2-CH3.