Patent ID: 9328074
Filing Date: 2016-05-03
CPC Classification: C07D

Claim Text:
1. A process for preparing isoxazoline derivatives represented by the general formula (1) wherein Ar 1 , Ar 2 represent aryl groups that may be substituted, and Ar 2 may or may not be the same as Ar 1 ; R represents an electron withdrawing group; characterized in that the isoxazoline derivatives represented by the general formula (1) are produced from the corresponding cyclopropane derivatives represented by the general formula (5) wherein Ar 1 , Ar 2 and R are as defined above, using the strategy of ring-opening and cyclization of the cyclopropane derivatives (5) with an electrophilic nitrosylation reagent at the temperature ranging from −20 to 100° C.