Patent ID: 9322755
Filing Date: 2016-04-26
CPC Classification: B01L,C12M,G01N

Claim Text:
1. A filter comprising: a first substrate having a first surface; a second substrate having a second surface bonded to the first surface; an inlet configured to accept a sample; an outlet configured to expel the sample; a flow passage disposed in the second surface such that the sample flows between the first and second surfaces from the inlet to the outlet; and a filter unit disposed in the flow passage to capture target cells or target particles from the sample flowing through the flow passage, wherein the filter unit comprises a barrier protruding from the second surface toward the first surface and a groove formed in a portion of the first surface corresponding to the barrier, the barrier and the groove forming a gap to narrow the flow passage, wherein the flow passage comprises a first end portion fluidly connected to the inlet, a second end portion fluidly connected to the outlet, and a center portion between the first end portion and the second end portion, further comprising a fluid resistance unit disposed in the flow passage between the filter unit and the inlet, wherein the fluid resistance unit is positioned relative to a perimeter wall in the first end portion of the flow passage to form micro-channels between the fluid resistance unit and the perimeter wall of the first end portion of the flow passage.