Patent ID: 9492401
Filing Date: 2016-11-15
CPC Classification: A61F,A61K,A61M,A61P,Y10T

Claim Text:
1. A transdermal drug-containing dosage unit which comprises a laminate comprising: a) a backing layer substantially impervious to the drug to be delivered transdermally; b) a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein a therapeutically effective amount of the drug and having a first initial rate of delivery of the drug; c) a second polymeric adhesive matrix, having dispersed therein a therapeutically effective amount of the drug and having a second initial rate of delivery of the drug, said second polymeric matrix in contact with a release liner; and d) at least one additional adhesive matrix, laminated in between said first and second polymeric adhesive matrices, having dispersed therein a therapeutically effective amount of the drug; each said additional adhesive matrix having an initial rate of delivery of the drug; wherein said initial rates of delivery of at least two of said matrices are different from one another; wherein on matrix comprises an acrylic adhesive, one matrix comprises a polvisobutylene adhesive and one matrix comprises a silicon adhesive; and wherein said drug comprises an estrogen or a combination of an estrogen and a progestin.