Patent ID: 9255063
Filing Date: 2016-02-09
CPC Classification: A61P,C07C

Claim Text:
1. A method of treating acute gouty arthritis and pain in attacks of acute gouty arthritis, cystic fibrosis, demyelinating diseases of central or peripheral origin, multiple sclerosis, Dupuytren's contracture, idiopathic pulmonary fibrosis, primary amyloidosis, recurrent pericarditis, acute pericarditis, asthma, postpericardiotomy syndrome, Behçet's disease, Familial Mediterranean fever, idiopathic thrombocytopenic purpura, primary biliary cirrhosis, or pyoderma gangrenosum, or prevention of attacks of acute gouty arthritis and pain in attacks of acute gouty arthritis, or chronic gout prophylaxis in a patient, comprising: administering to the patient in need thereof a therapeutically effective amount of a colchicine solid state form; wherein the colchicine solid state form comprises a. Colchicine Form B cyclohexane solvate comprising XRPD peak positions at 5.79, 10.50, 17.47, and 23.86±0.2 degrees 2-theta; b. Colchicine Form D ethanol solvate comprising XRPD peak positions at 9.45, 16.26, and 21.16±0.2 degrees 2-theta; c. Colchicine Form G acetone solvate comprising XRPD peak positions at 9.39, 16.44, and 18.87±0.2 degrees 2-theta; d. Colchicine Form H dioxane solvate comprising XRPD peak positions at 12.04, 15.78, 18.05, and 18.25±0.2 degrees 2-theta; e. Colchicine Form I tetrahydrofuran solvate comprising XRPD peak positions at 5.84, 10.64, and 17.61±0.2 degrees 2-theta; f. Colchicine Form J toluene solvate comprising XRPD peak positions at 9.46, 15.67, 18.10, and 24.26±0.2 degrees 2-theta; or g. Colchicine Form L mesitylene solvate comprising Raman peaks at 2935 and 1503±2 cm