Patent ID: 9389233
Filing Date: 2016-07-12
CPC Classification: A61K,A61P,C12Q,G01N

Claim Text:
1. A method of treating a subject having a myeloid tumour or a lymphoid tumour, wherein the tumour comprises: cells having a mutated TET2 gene having a nonsense mutation that encodes R1404Stop, Q321Stop, S354Stop, Q557Stop, or Y1724Stop in the resulting TET2 protein expressed by the tumour; cells having a mutated TET2 gene having a missense mutation that encodes S1898F, H1868R, G1869W, or L1872P in the resulting TET2 protein expressed by the tumour; or cells having a mutated TET2 gene encoding a frameshift at Q1834 or L1889 in the resulting TET2 protein expressed by the tumour; the method comprising: