Patent ID: 9452971
Filing Date: 2016-09-27
CPC Classification: C07C

Claim Text:
1. A method for manufacturing 3,5-dimethyl-1-adamantanamine, comprising: (i) reacting 3,5-dimethyl-1-adamantanol with an acid and nitrile in an organic solvent to obtain a reaction solution; (ii) adding water to the reaction solution obtained in (i) to obtain 1-amido-3,5-dimethyladamantane; and (iii) hydrolyzing 1-amido-3,5-dimethyladamantane obtained in (ii) in the presence of an inorganic base, and an alcohol-containing solvent comprising at least one alcohol selected from the group consisting of 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol, and 1-octanol.