Patent ID: 9505808
Filing Date: 2016-11-29
CPC Classification: A61K,A61P,C07K,C12N,C12P

Claim Text:
1. A or recombinant baculovirus vector plasmid a polynucleotide comprising a sequence which encodes a polypeptide consisting of the following (a) and (b): (a) a PCV2 ORF2 protein having at least 90% sequence identity to SEQ ID NO:5 over the entire 233 amino acid length comprising: (b) the PCV2 ORF2 protein characterized in (a) and that it (i) contains at least one substitution mutation in the BC loop at amino acid position 63 wherein the at least one substitution is an amino acid residue other than an arginine residue or a lysine residue, and (ii) is expressed in a higher amount compared to an expressed PCV2 ORF2 protein that does not contain such mutation in the BC loop.