Patent ID: 9376389
Filing Date: 2016-06-28
CPC Classification: C07D

Claim Text:
1. A method for preparing a 2,2-difluoroethylamine of formula (III) comprising reacting 2,2-difluoroethylamine of formula (I) with a halide of formula (II) wherein Hal is chlorine, bromine or iodine, in the presence of diisopropylethylamine, wherein, in the formulae (II) and (III) A is a pyrid-2-yl, pyrid-4-yl or pyrid-3-yl radical each of which may be substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy or is pyridazin-3-yl, which may be substituted in the 6-position by chlorine or methyl, or is a pyrazin-3-yl, 2-chloropyrazin-5-yl or 1,3-thiazol-5-yl radical, which may respectively be substituted in the 2-position by chlorine or methyl, or is a pyrimidinyl, pyrazolyl, thiophenyl, oxazolyl, isoxazolyl, 1,2,4-oxadiazolyl, isothiazolyl, 1,2,4-triazolyl or 1,2,5-thiadiazolyl radical, which may be substituted by fluorine, chlorine, bromine, cyano, nitro, C wherein X is fluorine, chlorine, bromine, iodine, C Y is fluorine, chlorine, bromine, iodine, C