Patent ID: 9289536
Filing Date: 2016-03-22
CPC Classification: A61B,A61L,A61P

Claim Text:
1. A method of forming a material in situ by increasing the volume of an expandable member of a medical device in a patient, the method comprising: a. introducing into a tube in communication with a space inside the expandable member, or directly into the expandable member, a flowable aqueous solution comprising a first and a second water soluble polymer precursor, each water soluble polymer precursor having terminal functional groups, and, optionally, an initiator catalyst, b. introducing into the flowable aqueous solution from step (a) a thermally activated low temperature free radical initiator in powder form, c. allowing the free radical initiator to dissolve in the flowable aqueous solution, wherein there is a filter disposed in the tube upstream from the expandable member, the filter having upstream and downstream sides, the free radical initiator disposed on the upstream side of the filter, whereby as the flowable aqueous solution passes through the filter, the free radical initiator dissolves therein, d. if not previously introduced in step (a), introducing the initiator catalyst into the solution from step (c), and e. allowing functional groups on the water soluble polymer precursors to undergo covalent bonding to form a solid and substantially non-biodegradable material in the space inside the expandable member.