Patent ID: 9415118
Filing Date: 2016-08-16
CPC Classification: A61K,A61P,C07K

Claim Text:
1. An antibody drug conjugate of the formula or a pharmaceutically acceptable salt thereof; wherein Ab is an antibody or antigen binding fragment thereof that specifically binds to human FGFR2; wherein the antibody comprises a heavy chain variable region that comprises: (a) a VH CDR1 of SEQ ID NO: 21, (b) a VH CDR2 of SEQ ID NO: 22, (c) a VH CDR3 of SEQ ID NO: 23; and a light chain variable region that comprises: (d) a VL CDR1 of SEQ ID NO: 31, (e) a VL CDR2 of SEQ ID NO: 32, (f) a VL CDR3 of SEQ ID NO: 33, wherein the CDR is defined in accordance with the Kabat definition; and n is an integer from 1 to 10.