Patent ID: 9512171
Filing Date: 2016-12-06
CPC Classification: C07K

Claim Text:
1. A method for manufacturing a functional molecule, comprising: taking a solution comprising functional molecule candidates wherein said functional molecule candidate is a modified nucleotide n-mer (n>=2) comprising a modified nucleoside having a substituent group, and wherein said functional molecule can be transformed into a nucleic acid when said substituent group is removed by alkali treatment; binding, to a resin, a specific substance having a cleavable linker which is a site that is cleavable under a specific condition to prepare a specific-substance-bound resin; treating said specific-substance-bound resin with said solution comprising said functional molecule candidates; cleaving said cleavable linker under said specific condition and selecting a functional molecule which has interacted specifically with said specific substance; removing said substituent group of said functional molecule by alkali treatment to produce a nucleic acid; and identifying said nucleic acid, thereby identifying said functional molecule wherein said functional molecule candidate is a modified nucleotide n-mer (n>=2) comprising a modified nucleoside having the substituent group attached to a nucleotide base.