Patent ID: 9328115
Filing Date: 2016-05-03
CPC Classification: A61P,C07D

Claim Text:
1. A process for preparing a trihydrate form of the compound of Formula 1, which comprises: (a) dissolving a dry methanol solvate of the compound of Formula 1 in a crystalline form having a power X-ray diffraction spectrum comprising peaks at 8.62, 9.76, 12.17, 12.56, 12.99, 15.23, 16.20, 17.20, 18.33, 19.79, 20.24, 21.34, 22.03, 23.69, 24.54, 25.19, and 26.31 °2θ (±0.2°) in water to obtain a solution; (b) adding an anti-solvent to the solution obtained from step (a) to form a precipitate; and (c) isolating the precipitate from the mixture obtained from step (b).