Patent ID: 9295631
Filing Date: 2016-03-29
CPC Classification: A61K,A61Q,C12N

Claim Text:
1. A method of lightening skin comprising the step of applying on to a desired surface of the skin a skin lightening composition comprising: (a) an siRNA comprising an oligonucleotide comprising a sequence selected from the group consisting of and a portion comprising at least 19 nucleotides thereof; and (b) a cosmetically acceptable vehicle; wherein the oligonucleotide has a function to suppress an expression of a gene corresponding to a receptor selected from the group of receptors consisting of: c-Kit Tyrosine kinase receptor, Endothelin receptor A (EDNRA), Endothelin receptor B (EDNRB), Melanocortin 1 receptor, and Frizzled 1 (Fz1) receptor; and wherein a size of the oligonucleotide is from 19 to 30 nucleotides.