Patent ID: 9388190
Filing Date: 2016-07-12
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A method of treating a subject with disease or disorder selected from hepatic steatosis, nonalcoholic steatohepatitis (NASH), nonalcoholic fatty liver disease (NAFLD), atherosclerosis, xerosis, skin aging, wrinkling, dyslipidemia, acne, hyperseborrhoea of acne, simple seborrhea, seborrhoeic dermatitis, Alzheimer's disease, cutaneous atopy, hyperphosphatemia, cardiovascular complications of hyperphosphatemia, lupus erythematosis, diabetes mellitus, skin disorders due to exposure to UV radiation, photo-induced or chronological aging of the skin, actinic pigmentations, pathology associated with chronological or actinic aging, Niemann-Pick disease type C, inflammation, stroke, xanthoma, hyperlipidemia, metabolic syndrome, syndrome X, peripheral occlusive disease, proteinuria, glomerulopathies, diabetic nephropathy, hypertensive nephropathy, IGA nephropathy, focal segmental glomerulosclerosis, and psoriasis comprising administering to the subject an effective amount of a compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein: X is N or CR R R R R Each R independently is H or alkyl; R R