Patent ID: 9393329
Filing Date: 2016-07-19
CPC Classification: A61K,C07C,C07D

Claim Text:
1. A method of detecting, imaging, and/or monitoring a patient comprising the steps of: administering to the patient a chelated imaging agent; and acquiring an image of a site of concentration of the chelated imaging agent in the patient by a diagnostic imaging technique; wherein the chelated imaging agent comprises a compound comprising at least one chelator moiety, and an imaging agent bound to the at least one chelator moiety; wherein the compound is of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is N, R R R wherein each R or wherein at least one of R wherein n is 0 or greater, m is 0 or greater, and R c is a chelator moiety; R R each R each R n′ is an integer from 1-3; wherein the chelator moiety comprises the structure: wherein: each R′ is a group capable of coordinating a metal ion; and R″ is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkylaryl, alkylcarbonyl, aryl, arylalkyl, alkylarylalkyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, heteroalkyl, heterocyclyl, heterocyclylalkyl, or substituted derivatives thereof.