Patent ID: 9474750
Filing Date: 2016-10-25
CPC Classification: A61K,Y10S

Claim Text:
1. A sustained release oral dosage form, comprising: (A) an orally therapeutically effective dose of an opioid agonist selected from oxycodone and pharmaceutically acceptable salts thereof; (B) an opioid antagonist selected from naltrexone, naloxone, nalmephene, cyclazocine, levallorphan, and mixtures thereof, and pharmaceutically acceptable salts thereof; and (C) a sustained release carrier that contains said opioid agonist and said opioid antagonist; said dosage form having a ratio of said opioid antagonist to said opioid agonist that provides a combination product which is analgesically effective when the combination is administered orally, but which is aversive in physically dependent human subjects when abused at a higher dose than said therapeutically effective dose.