Patent ID: 9476029
Filing Date: 2016-10-25
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method of producing dendritic cell (DC) progenitor cells, said method comprising: culturing a population of hematopoietic stem/progenitor cells (HPCs) in a first feeder culture comprising kit ligand (KL), fms-like tyrosine kinase 3 ligand (FL), thrombopoietin (TPO), IL-3, IL-6 and basic fibroblast growth factor (bFGF) under conditions to produce a population of first expanded cells; wherein the first feeder culture does not comprise GM-CSF or IL-15; culturing said first expanded cells in a second feeder culture comprising KL, FL, TPO, IL-3, IL-6, bFGF, GM-CSF and IL-15 under conditions to produce DC progenitor cells (DCPs).