Patent ID: 9320842
Filing Date: 2016-04-26
CPC Classification: A61M,B01D

Claim Text:
1. A multimodal dialysis apparatus, comprising: a blood circuit for transporting blood extracorporeally to a hemodialysis unit; a dialysate circuit for transporting a fluid to contact the hemodialysis unit, wherein the fluid increases in concentration with at least one waste species during operation; an infusate pump for adding a potassium salt to the fluid in the dialysate circuit; and a composition sensor comprising a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of blood in the blood circuit and fluid in the dialysate circuit, a purification unit comprising an electrodialysis unit having a diluate chamber and a concentrate chamber and a means for producing an electric field, wherein one or more ions are removed from the fluid in the dialysate circuit; a reverse osmosis unit located at an outlet of the purification unit to selectively remove solutes from the fluid; a conditioning unit comprising urease; wherein the conditioning unit is located at an outlet of the reverse osmosis unit; and a conduit connecting an outlet of the conditioning unit to an inlet of the electrodialysis unit for returning fluid exiting the conditioning unit to the electrodialysis unit; wherein the infusate pump is controlled by a controller to adjust a rate of addition of potassium ions to the fluid in the dialysate circuit based at least in part on data from the composition sensor.