Patent ID: 9308225
Filing Date: 2016-04-12
CPC Classification: A61K,A61L,A61P

Claim Text:
1. A method of treating post-operative atrial fibrillation in a subject, comprising: providing an extracellular matrix (ECM) composition comprising acellular ECM from a mammalian tissue source, said tissue source comprising small intestine submucosa, wherein, when said ECM composition is administered to damaged myocardium tissue of said subject, said ECM composition induces myofibroblast proliferation and angiogenesis and, thereby, bioremodeling and regeneration of new myocardium tissue; and delivering a therapeutically effective amount of said ECM composition directly to post-operative damaged myocardium tissue of said subject, wherein said ECM composition, wherein said ECM composition modulates electrical activity in the heart of said subject, whereby said ECM composition reduces incidence of post-operative atrial fibrillation of said subject.