Patent ID: 9433646
Filing Date: 2016-09-06
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method of inhibiting growth of a neoplastic cell, the method comprising: (a) providing a cell free-placental extract made by the process comprising: (i) obtaining human placenta; (ii) homogenizing the obtained human placenta by digesting the obtained human placenta with a collagenase and a heparitinase, wherein the heparitinase digestion is at a neutral pH, the homogenization resulting in a homogenate; (iii) centrifuging said homogenate to produce a supernatant free of cellular debris; and (iv) purifying the supernatant to obtain cell free-placental extract comprising a cell differentiation-inducing fraction having a molecular weight in the range from about 10 Daltons to about 10,000 Daltons (b) directly administering said cell free-placental extract to the neoplastic cell which is selected from the group consisting of a leukemia cell, and a prostate cancer cell, thereby inhibiting growth of the neoplastic cell.