Patent ID: 9289390
Filing Date: 2016-03-22
CPC Classification: A61K,A61P

Claim Text:
1. A pharmaceutical composition comprising a taste masked multi-layered particle, the multi-layered particle comprising: a) an inert core, b) at least one coating layer that comprises a pharmaceutically active ingredient and a binder, c) an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and comprising a water-soluble pharmaceutical film-forming compound, selected from the group consisting of hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) poly(1-vinylpyrrolidin-2-one) (PVP), and any combination thereof, and d) an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising wherein the pharmaceutically active ingredient is water-soluble and comprises either at least one basic group and/or a bitter taste; wherein the pharmaceutical composition is in solid form with a mass of 20 to 4000 mg per unit.