Patent ID: 9366681
Filing Date: 2016-06-14
CPC Classification: C07K,C12Q,G01N

Claim Text:
1. A method of diagnosing arteriosclerosis in a subject comprising: obtaining a serum sample from the subject; determining the presence in the serum sample of an antibody capable of forming a complex with a solid-phased polypeptide having an amino acid sequence set forth in SEQ ID NO: 31 of the Sequence Listing, or a fragment thereof, using a process comprising contacting the solid-phased polypeptide with the serum sample under conditions that allow for antibodies in the serum sample to form a complex with the polypeptide, exposing the antibody-peptide complex to a second antibody capable of binding to the antibodies in the antibody-peptide complex, and detecting a signal from the second antibody indicating the presence in the serum of an antibody capable of forming a complex with the amino acid sequence set forth in SEQ ID NO: 31 of the Sequence Listing, or a fragment thereof; and diagnosing arteriosclerosis in the subject if antibodies are identified in the serum that are capable of forming a complex with the amino acid sequence set forth in SEQ ID NO: 31 of the Sequence Listing, or a fragment thereof.