Patent ID: 9250211
Filing Date: 2016-02-02
CPC Classification: C07K,G01N

Claim Text:
1. A method for purifying lipoproteins suitable for differential charged-particle mobility analysis of lipoprotein class and subclass, said method comprising: (a) adding one or more cations and dextran sulfate to a sample comprising lipoproteins to form a precipitation mixture; (b) contacting the precipitation mixture with a microbead under conditions for one or more classes or subclasses of lipoproteins in said mixture to bind to an inert outer layer of the microbead, wherein said inert outer layer comprises carboxylate or NH (c) separating lipoproteins bound to the microbead from said mixture to obtain a microbead with bound lipoproteins; and (d) removing said bound lipoproteins from the microbead; wherein said lipoproteins bound to the microbead comprise HDL and one or more selected from the group consisting of LDL, Lp(a), IDL and VLDL.