Patent ID: 9393243
Filing Date: 2016-07-19
CPC Classification: A61K,A61P,Y02A

Claim Text:
1. A pharmaceutical composition formulated for: a. topical application to a body surface, and b. antibacterial activity localized to the body surface, the pharmaceutical composition consisting essentially of: a therapeutically effective amount of a non-betaine form ciprofloxacin; at least one member selected from the group consisting of a pH adjusting agent and a preservative; water; and a pH of from more than 6 to about 8.5, wherein: more than 10% of the non-betaine form ciprofloxacin is in the pharmaceutical composition in suspended form; the body surface is: at least one member of the group consisting of a dermal surface, an ophthalmic surface, a mucosal surface, and a fingernail surface, and/or in at least one member selected from the group consisting of an ear canal, an oral cavity, a pharyngeal cavity, a nasal cavity, a pulmonary cavity, a vaginal cavity, and a rectal cavity; and the pharmaceutical composition exhibits a more rapid onset of antibacterial activity than a comparator formulation that differs from the pharmaceutical composition by having: a pH of about 4.5 and 5% or less of the non-betaine form ciprofloxacin in suspension.