Patent ID: 9421246
Filing Date: 2016-08-23
CPC Classification: A61F,A61K,A61P

Claim Text:
1. A method of inducing weight loss in a patient, comprising: ingesting one or more ingestible tablets formed in a packed mass, the ingestible tablets comprising a biocompatible polymer in combination with a solubilizer/stabilization propylene glycol alginate agent which is adapted to maintain the polymer as a firm solid, wherein the polymer is adapted to (i) swell upon absorbing water from gastric fluid to increase its size, thereby promoting its gastric retention, (ii) maintain its physical integrity in a stomach for at least 2 hours, and (iii) wherein the polymer includes one or more lipase-sensitive, fatty acid-like polymerizable groups or cross-linking groups such that the polymer is further degradable by an intestinal enzyme or exposure to an intestinal pH; maintaining, a reduction of gastric volume within a stomach of the patient for at least 2 hours via the one or more ingestible tablets such that a sensation of fullness is induced in the patient without releasing a drug which induces the sensation; and disintegrating, an acid-sensitive gelatin coating, covering each of the one or more ingestible tablets within the stomach of the patient such that the one or more ingestible tablets disintegrate in the gastric fluid and disperse in the stomach at a first degradation rate; and further disintegrating the one or more ingestible tablets within an intestinal tract of the patient at a second degradation rate which is higher than the first degradation rate, and wherein the second degradation rate is sufficiently rapid to substantially prevent a small bowel obstruction by the polymer.