Patent ID: 9523662
Filing Date: 2016-12-20
CPC Classification: B01D,G01N

Claim Text:
1. A method for reducing pressure disturbances caused by introducing a low-pressure sample into a high-pressure solvent mixture stream, comprising: calculating a number of strokes of a pump needed to deliver a solvent mixture stream through a pre-injection dwell volume from the pump to an injector valve of an autosampler; counting strokes of the pump during a delivery of the solvent mixture stream through the pre-injection dwell volume from the pump to the injector valve of the autosampler; and switching, in response to a stroke count equaling the calculated number of strokes, the injector valve to introduce the sample to the solvent mixture stream during a pump transfer period during which a primary piston of the pump transfers a solvent stream to an accumulator piston of the pump and during which the pump performs pressure control to compensate for a drop in pressure.