Patent ID: 9322047
Filing Date: 2016-04-26
CPC Classification: B01L,C12M,C12Q,G01N

Claim Text:
1. A device for capturing target cells, comprising: a main microchannel having a first portion, a second portion, an inlet and an outlet, the first portion having a first portion depth that is larger at the inlet of the main microchannel and tapers to a depth in the order of the diameter of the target cells along the length of the first portion, the second portion having a second portion width that is smallest at a connection with the first portion and that increases along a second portion length of the second portion, the second portion having a second portion depth in the order of a diameter of the target cells; and at least two side microchannels connected to the main microchannel on opposite sides of the first portion of the main microchannel, each of the at least two side microchannels having a side microchannel width, a side microchannel depth and a side microchannel length, wherein the side microchannel depths are sufficiently smaller than the diameter of the target cells such that the target cells cannot pass through the at least two side microchannels, wherein a capture elements is immobilized on at least one interior surface of the main microchannel.