Patent ID: 9265814
Filing Date: 2016-02-23
CPC Classification: A61K,A61P,Y02A

Claim Text:
1. A method for delivering a biologically active molecule to the eye, the method comprising implanting at least one micronized device for delivery of a therapeutic dose of a biologically active molecule to the eye comprising a capsule into the eye or surrounding the eye and allowing said biologically active molecule to diffuse from the device into the vitreous, the aqueous humor, or the periocular space of the eye, wherein the capsule comprises: a) a core comprising between about 5×10 and wherein the cells are distributed thereon, and b) a biocompatible jacket surrounding said core, the jacket having a molecular weight cutoff permitting diffusion of the biologically active molecule into the eye, wherein the device is configured as a cylinder with an outer diameter of between 200 and 350 μm and a length of between 0.5 and 6 mm, wherein the therapeutic dosage of the biologically active molecule that diffuses into the eye is between 0.1 pg and 1000 ng per eye per patient per day for a period greater than three months.