Patent ID: 9453061
Filing Date: 2016-09-27
CPC Classification: A61K,C07K,C12N

Claim Text:
1. A method for treating a protein serine/threonine phosphatase-related disease, the method comprising the steps of: administering to the subject a composition that disrupts interaction between a protein inhibitor RCAN1 (SEQ ID NO:1) and a protein serine/threonine phosphatase calcineurin in the subject, wherein the protein inhibitor inhibits at least one function of the calcineurin protein serine/threonine phosphatase, wherein the composition comprises a peptide comprising an amino acid sequence selected from the group of SEQ ID nos: 3, 5, 7, 8, 13, and 14; increasing the function of the calcineurin protein serine/threonine phosphatase compared to the function prior to the administering and decreasing a symptom of the calcineurin protein serine/threonine phosphatase-related disease; thereby treating the subject for the disease wherein the disease is Down syndrome or type II diabetes.