Patent ID: 9289427
Filing Date: 2016-03-22
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A method for the treatment of kidney cancer, kidney cell carcinoma, lung cancer, lung adenocarcinoma, small cell lung carcinoma, or bronchial carcinoma, which in each case is caused, mediated, or propagated by Met-kinase, said method comprising administering to a patient an effective amount of a compound selected from the following compounds: (a) a crystalline form of a hydrochloride solvate of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile, excluding 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride monohydrate in the form of a polymorph characterized by the following XRD data: or (b) the hydrochloride anhydrate of the compound 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile.