Patent ID: 9381202
Filing Date: 2016-07-05
CPC Classification: A61K,A61P,C07C,C07D

Claim Text:
1. A method for the preparation of a salt of a compound of Formula I comprising: reacting one equivalent of a cation source selected from the group consisting of an alkali metal hydroxide or an organic cation source comprising an ammonium or at least one tertiary amine group with a compound of Formula I, wherein: R R X is a 1, 2 or 3 carbon atom chain, wherein each atom is optionally substituted with halogen, hydroxyl, lower alkyl, substituted lower alkyl, lower alkoxy, cycloalkyl, substituted cycloalkyl, or substituted lower alkoxy, provided however that when an atom of the chain is substituted with substituted lower alkyl, substituted lower alkoxy or substituted cycloalkyl, then the substituent does not include an amino group; and ring B is polyunsaturated or aromatic; said compound of Formula I is dissolved in a solvent selected from the group consisting of acetonitrile, low molecular weight ketones, tetrahydrofuran, 2-methyltetrahydrofuran, dimethylformamide and n-methyl pyrrolidinone, and removing the solvent.