Patent ID: 9238692
Filing Date: 2016-01-19
CPC Classification: A61K,A61M,A61P,C07K

Claim Text:
1. A pre-filled syringe composition comprising a liquid pharmaceutical formulation, wherein the liquid pharmaceutical formulation comprises: (a) 100±10 mg/mL to 200±20 mg/mL of an antibody or antigen-binding fragment thereof that specifically binds human interleukin-4 receptor alpha (hIL-4Rα), wherein the antibody comprises a heavy chain variable region (HCVR) comprising the amino acid sequence of SEQ ID NO: 1, and a light chain variable region (LCVR) comprising the amino acid sequence of SEQ ID NO:5; (b) 10 mM to 15 mM acetate; (c) 15 mM to 25 mM histidine; (d) 2.5% w/v to 10% w/v sucrose; (e) 0.1% w/v to 0.3% w/v polysorbate; and (f) 20 mM to 100 mM arginine; wherein said liquid pharmaceutical formulation has a pH of from 5.6 to 6.2 and is contained within a syringe.