Patent ID: 9522937
Filing Date: 2016-12-20
CPC Classification: A01N,C07K,C12N,Y02A

Claim Text:
1. An isolated nucleic acid molecule encoding an engineered hybrid insecticidal protein comprising in an N-terminus to C-terminus direction an N-terminal region of a Cry3A protein fused to a C-terminal region of a Cry1Aa or Cry1Ab protein, wherein at least one crossover position between the Cry3A protein and the Cry1Aa or Cry1Ab protein is located in conserved block 2, conserved block 3 or variable region 4, and optionally comprising: (a) at the C-terminus a protoxin tail region of a Bt Cry protein; or (b) at the N-terminus a peptidyl fragment; or (c) both (a) and (b), wherein the engineered hybrid insecticidal protein has at least 80% identity to SEQ ID NO:64 and has insecticidal activity against western corn rootworm ( Diabrotica virgifera ).