Patent ID: 9402813
Filing Date: 2016-08-02
CPC Classification: A61K,A61P

Claim Text:
1. A solid oral pharmaceutical composition for treatment of pain, and reduction or prevention of nausea or vomiting associated with an opioid analgesic, comprising: a layer formulated for immediate-release that comprises an antiemetic; and a layer formulated for controlled-release that comprises an opioid analgesic and a non-opioid analgesic, wherein the opioid analgesic, the non-opioid analgesic, and the antiemetic are present in a ratio by weight of (1 to 2):(40 to 45):(1 to 2), respectively, and wherein the solid oral pharmaceutical composition provides an effective amount of the antiemetic to reduce or prevent nausea associated with the opioid analgesic or vomiting associated with the opioid analgesic in a subject in need thereof, and an effective amount of the opioid analgesic and the non-opioid analgesic to treat pain in the subject in need thereof.