Patent ID: 9388130
Filing Date: 2016-07-12
CPC Classification: A61K,A61P,C07B,C07C

Claim Text:
1. A retinyl ester selected from the group consisting of a 9-cis-retinyl ester of Formula I and an 11-cis-retinyl ester of Formula II, wherein A is CH 2 OR and —R, when taken together with the adjacent oxygen is a carboxylate radical of a C 2 to C 10 polycarboxylic acid: wherein the ester substituent is selected from the group consisting of oxalate, malonate, succinate, citrate, ketoglutarate, fumarate, malate, glutarate, adipate, pimelate, suberate, azelate, sebacate, and oxaloacetate; wherein the retinyl ester is a pro-drug that, when administered to a subject, is metabolically transformed into a retinal capable of binding opsin.