Patent ID: 9486524
Filing Date: 2016-11-08
CPC Classification: A61K,A61P

Claim Text:
1. A kit comprising: a first composition comprising a first compound provoking lymphocytopenia, wherein the first compound is an anti-thymocyte immunoglobulin (ATG) present in an amount capable of provoking transient T cell depletion; a second composition comprising a second compound having selective affinity for professional antigen presenting cells (APC), wherein said second compound is covalently coupled to a T cell epitope of an antigen from cellular malignancy, dysplasia, tumour or cancer, and wherein said second compound is selected from the group consisting of adenylate cyclases (CyaA), heat shock proteins (HSP), shigatoxin and LAG-3; and wherein the antigen from cellular malignancy, dysplasia, tumour or cancer is selected from the group consisting of carcino-embryonic antigen (CEA), MAGE -A3, telomerase (TERT), E7 oncogene from the human papilloma virus (HPV) and P53; for sequential use in the treatment and/or prevention of cellular malignancy, dysplasia, tumour or cancer in a patient.