Patent ID: 9320478
Filing Date: 2016-04-26
CPC Classification: A61B

Claim Text:
1. A method of positron emission tomography (PET) comprising: labeling a first probe with a first positron emitting radionuclide to provide a first labeled probe, wherein the first probe is a selective probe that includes an antibody or ligand that is biologically responsive to receptor or antigen status; labeling a second probe with a second positron emitting radionuclide to provide a second labeled probe, wherein the second probe is a metabolic probe; wherein one of the first and second radionuclides provides double coincidence events in PET by emission of a positron, and the other of the first and second radionuclides provides triple coincidence events in PET by emission of a positron and a gamma ray photon; introducing the first and second labeled probes into an imaging subject simultaneously; performing PET on the imaging subject with a PET system capable of simultaneously providing double coincidence and triple coincidence PET images; wherein the PET system includes a detector that is responsive to the gamma ray photon, and is not responsive to photons generated by positron annihilation.