Patent ID: 9409981
Filing Date: 2016-08-09
CPC Classification: A61K,A61P,C07K,H05K

Claim Text:
1. A method of treating a GDF8-associated disorder in a subject, comprising administering to a subject in need of treatment for a GDF8-associated disorder a therapeutically effective amount of an anti-GDF8 antibody or antigen binding fragment thereof that specifically binds to GDF8 comprising: an antibody variable heavy (VH) region comprising the first, second and third complementarity determining regions (CDRs) from the VH region defined by the amino acid sequence of SEQ ID NO:14 or SEQ ID NO:17; and an antibody variable light (VL) region comprising the first, second and third CDRs from the VL region defined by the amino acid sequence of SEQ ID NO:16 or SEQ ID NO:18, wherein the GDF8-associated disorder is selected from the group consisting of a muscular disorder and a neuromuscular disorder, wherein the muscular disorder or neuromuscular disorder is characterized by insufficient muscle mass or strength.