Patent ID: 9394529
Filing Date: 2016-07-19
CPC Classification: A61K,A61P,C11D,C12N,C12Q,C12Y,G01N

Claim Text:
1. A synthetic or recombinant nucleic acid or polynucleotide comprising or consisting of: (a) a nucleic acid sequence encoding a polypeptide having phosphatidylinositol-specific phospholipase C (PI-PLC) enzyme activity, and (b) the nucleic acid sequence of (a) encoding a polypeptide having PI-PLC enzyme activity but lacking a native signal sequence or proprotein amino acid sequence; (c) the nucleic acid sequence of (a) or (b) encoding a polypeptide having PI-PLC enzyme activity but lacking a native promoter sequence; (d) the nucleic acid of (c) further comprising a heterologous promoter sequence and/or other transcriptional regulatory sequence; (e) the nucleic acid sequence of any of (a) to (d) further comprising a heterologous nucleotide sequence; (f) the nucleic acid of (e), wherein the heterologous nucleotide sequence comprises a heterologous promoter sequence and/or encodes a heterologous amino acid sequence comprising a member selected from the group consisting of: (g) a nucleic acid sequence completely complementary to the nucleotide sequence of any of (a) to (f).