Patent ID: 9248129
Filing Date: 2016-02-02
CPC Classification: A61K,A61P,C07D

Claim Text:
1. A method of treating or reducing the risk of a disease or condition selected from Down's syndrome, β-amyloid angiopathy, cerebral amyloid angiopathy, MCI (“mild cognitive impairment”), neurodegeneration associated with Alzheimer's disease, neurodegeneration associated with dementia, pre-senile dementia, senile dementia, dementia associated with Parkinson's disease, and cortical basal degeneration, wherein said method comprises administering to a person suffering from, or at risk of, said disease or condition, a therapeutically effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: A is —O— or —CH n is 0 or 1; R R said C 0-6 alkylaryl, C 0-6 alkylheteroaryl, C 2-6 alkynyl, C 2-6 alkenyl, C 1-6 alkyl or C 1-6 haloalkyl is optionally substituted with one to three R 7 ; as to R 5 and R 6 : R said heterocyclyl, C R a 3-14 membered cycloalkyl or heterocyclyl monocyclic ring, or a 9-14 membered bicyclic cycloalkyl or heterocyclyl ring; optionally substituted by one or two substituents independently selected from oxo, halogen, C each R said C each R said C R said heteroaryl is optionally substituted with halogen, cyano, OR