Patent ID: 9334530
Filing Date: 2016-05-10
CPC Classification: B01J,B82Y,C12Q

Claim Text:
1. A method of making and imaging arrays, comprising: a) providing i) first and second proteins, ii) first and second photocleavable mass tags and iii) first and second beads, said beads comprising a binding agent used to bind said proteins to said beads, wherein said first protein is bound only to said first bead through said binding agent and said second protein is bound only to said second bead through said binding agent, wherein said first photocleavable mass tag is attached to said first bead and said second photocleavable mass tag is attached to said second bead and wherein said photocleavable mass tags attached to said first and second beads are of different mass, and wherein at least one of said first and second beads comprises a detectable label; b) creating an array with said first and second beads; c) imaging said array to determine the presence of said detectable label; and d) subjecting said array directly to mass spectrometry analysis under conditions such that at least one of said first and second beads is identified by detection of its corresponding photocleavable mass tag, thereby identifying at least one of said first or second proteins in said imaged array.