Patent ID: 9440941
Filing Date: 2016-09-13
CPC Classification: A61P,C07D,C07F

Claim Text:
1. A compound of the formula I, in any of its stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, or a pharmaceutically acceptable salt thereof, wherein Ar is phenyl which is unsubstituted or substituted by one or more identical or different substituents R0; R0 is selected from the series consisting of halogen, (C R1 is hydrogen or one or more identical or different substituents selected from the series consisting of fluorine and (C R2 is selected from the series consisting of hydrogen, (C R3 is selected from the series consisting of hydrogen and (C or the groups R2 and R3 together are oxo; R4 is hydrogen or one or more identical or different substituents selected from the series consisting of halogen, (C R5 and R6 are independently of one another selected from the series consisting of hydrogen, (C or the groups R5 and R6, together with the nitrogen atom carrying them, form a 4-membered to 7-membered, monocyclic, saturated or partially unsaturated heterocycle which, in addition to the nitrogen atom carrying R5 and R6, comprises 0 or 1 further ring heteroatom selected from the series consisting of nitrogen, oxygen and sulfur, and which is unsubstituted or substituted by one or more identical or different substituents R21; R7 is selected from the series consisting of (C R8 is selected from the series consisting of hydrogen and (C R9 is selected from the series consisting of (C R10 is selected from the series consisting of hydrogen, (C R20 is selected from the series consisting of R24, fluorine, HO—, oxo, (C R21 is selected from the series consisting of (C R22 is selected from the series consisting of halogen, (C R24 is a 3-membered to 10-membered, monocyclic or bicyclic ring which is saturated, partially unsaturated or aromatic and comprises 0, 1, 2, 3 or 4 identical or different ring heteroatoms selected from the series consisting of nitrogen, oxygen and sulfur, and which is unsubstituted or substituted by one or more identical or different substituents R22; R30 and R33 are independently of one another selected from the series consisting of (C R31 and R32 are independently of one another selected from the series consisting of hydrogen, (C or the groups R31 and R32, together with the nitrogen atom carrying them, form a 4-membered to 7-membered, monocyclic saturated heterocycle which, in addition to the nitrogen atom carrying R31 and R32, comprises 0 or 1 further ring heteroatom selected from the series consisting of nitrogen, oxygen and sulfur, and which is unsubstituted or substituted by one or more identical or different substituents selected from the series consisting of fluorine and (C R34 is selected from the series consisting of hydrogen, (C Het1 is a 5-membered or 6-membered, monocyclic, aromatic heterocycle which comprises 1, 2 or 3 identical or different ring heteroatoms selected from the series consisting of nitrogen, oxygen and sulfur, and which is unsubstituted or substituted by one or more identical or different substituents selected from the series consisting of halogen, (C Het2 is a 4-membered to 10-membered, monocyclic or bicyclic, saturated or partially unsaturated heterocycle which comprises 1 or 2 identical or different ring heteroatoms selected from the series consisting of nitrogen, oxygen and sulfur; n is selected from the series consisting of 0, 1 and 2, wherein all numbers n are independent of one another; p and q are independently of one another selected from the series consisting of 0 and 1; wherein all phenyl groups are unsubstituted or substituted by one or more identical or different substituents selected from the series consisting of halogen, (C wherein all cycloalkyl and bicycloalkyl groups, independently of any other substituents which can be present on a cycloalkyl or bicycloalkyl group, can be substituted by one or more identical or different substituents selected from the series consisting of fluorine and (C wherein all alkyl groups, independently of any other substituents which can be present on an alkyl group, can be substituted by one or more fluorine substituents.