Patent ID: 9334367
Filing Date: 2016-05-10
CPC Classification: A61K,A61P,C08G,C12N

Claim Text:
1. A nanoparticle comprising a polyol-containing polymer, a boronic acid-containing polymer, and at least one targeting ligand molecule; wherein the boronic acid-containing polymer having a structure of formula: wherein R X Y Functional group 2 independently comprises —OCH r is 1; a is 0; and b is 1; and said boronic acid-containing polymer being coupled to the polyol-containing polymer with reversible borate ester linkages formed between the —B(OH) said targeted nanoparticle being configured to present the boronic acid-containing polymer to an environment external to the nanoparticle; and wherein the boronic acid-containing polymer is conjugated to the at least one targeting ligand molecule by coupling with the or Functional group 2.