Patent ID: 9522263
Filing Date: 2016-12-20
CPC Classification: A61L,A61M,A61P,Y10T

Claim Text:
1. A device for delivery of a rheumatoid arthritis drug across a dermal barrier, the device comprising: a microneedle and a plurality of nanostructures and microstructures projecting directly outward from a surface of the microneedle in a predetermined pattern, wherein at least a portion of the microstructures have a cross-sectional dimension of greater than about 500 nanometers and less than about 10 micrometers and a height of from about 20 nanometers to about 1 micrometer, and wherein at least a portion of the nanostructures have a cross-sectional dimension of less than about 500 nanometers and greater than about 5 nanometers and an aspect ratio of from about 0.2 to about 5, wherein the microneedle further contains a channel; and a reservoir that is in fluid communication with the channel of the microneedle and that contains a rheumatoid arthritis drug.