Patent ID: 9304130
Filing Date: 2016-04-05
CPC Classification: B82Y,G01N

Claim Text:
1. A method of forming a sample assembly of a biological sample having target antigens, the method comprising: forming a base layer on a substrate; forming an outer layer on the base layer; forming at least one sample trench within the outer layer using one or more of a milling technique and a lithography technique, wherein said sample trench has a bottom surface; forming a plurality of magnetic servo alignment marks on said sample assembly; bonding a first set of antibodies within said at least one sample trench on a first surface of said base layer; exposing said at least one sample trench with said first set of bonded antibodies to said biological sample having said target antigens, wherein said target antigens bond with said first set of antibodies within said at least one sample trench; bonding a second set of antibodies to nanoparticles; and exposing said target antigens within said at least one sample trench to said second set of antibodies bonded to said nanoparticles, wherein said second set of antibodies bond with said target antigens within said at least one sample trench.