Patent ID: 9486578
Filing Date: 2016-11-08
CPC Classification: A61M,G16H

Claim Text:
1. A method to control an infusion pump with a controller to control the pump and receive data from at least one glucose sensor, the method comprising: measuring glucose level in the subject with the glucose sensor to provide at least one glucose measurement in each time interval in a series of discrete time interval index (“k”); obtaining in the controller a glucose calibration measurement of the glucose sensor during at least one time interval in the series of time interval index to provide for a calibration index; ascertaining whether one or more glucose measurements were not provided by the glucose sensor during a time interval of the series of time interval index to provide for an omission index; determining a tuning factor based on both the calibration index and omission index; calculating insulin amount for delivery by the controller based on a model predictive controller that utilizes (a) the plurality of glucose measurements to predict a trend of the glucose level from estimates of a metabolic state of the subject and (b) the tuning factor so as to provide a calculated insulin amount to be delivered to the subject for each interval of the interval index; delivering insulin amount determined from the calculating step with the infusion pump.