Patent ID: 9283285
Filing Date: 2016-03-15
CPC Classification: A61K,A61P

Claim Text:
1. A stable self-assembled composition comprising (i) a carrier and targeting system comprising nanoparticles formed by self-assembly of an optionally modified polyanion, and optionally a polycation, which may also be modified, said nanoparticles having a surface; at least one targeting agent which is linked to the surface of the nanoparticle and to either the polycation/modified polycation or the polyanion/modified polyanion, or both; (ii) an active compound selected from the group of docetaxel and its pharmaceutically acceptable salts and derivatives; (iii) a PEGylating agent; (iv) a complexing agent or a metal ion, or both; and optionally (v) a stabilizer/formulating agent, wherein the nanoparticles are coated with PEG, and/or PEG-chain containing targeting agent at the end of the chain.