Patent ID: 9309114
Filing Date: 2016-04-12
CPC Classification: A61K,A61Q,B01J,B82Y,Y10T

Claim Text:
1. A process for producing porous nanoparticles, the process comprising: continuously adding a resin composition comprising at least one resin to a feed section of a screw extruder, wherein the screw extruder is segmented and at least one of the segments is heated to a temperature of from 70° C. to 200° C.; adding a first aqueous solution comprising a surfactant to the resin composition to form a water-in-oil emulsion in the screw extruder which results in the surfactant within the resin; adding a second aqueous solution comprising deionized water to the water-in-oil emulsion in the screw extruder to form a water-in-oil-in-water double emulsion comprising porous nanoparticles having cell walls with a cell wall thickness in the range of from about 10 nm to about 50 nm; and recovering porous nanoparticles from the double emulsion in the screw extruder; wherein the porous nanoparticles have a particle size of from about 50 nm to about 2 μm and a pore diameter of from about 20 nm to about 400 nm; wherein each of the solutions and the composition utilized during the process of forming the porous nanoparticles are substantially free of organic solvents.