Patent ID: 9375223
Filing Date: 2016-06-28
CPC Classification: A61B,A61M

Claim Text:
1. A method of treating vascular stenosis, comprising the steps of: performing balloon angioplasty at a treatment area inside a vessel; positioning a distal end of a vibrational device at the treatment area, the vibrational device having a transmission member; propagating vibrational energy through the transmission member from a proximal transducer located outside the patient to the distal end of the vibrational device at a frequency of 1 KHZ-20 MHZ while undergoing irrigation to form surface waves at the distal end of the vibrational device; applying the surface waves at a power of less than 20 Watts at the distal end of the vibrational device to the treatment area to change the stenosis compliance and to increase permeability of the vessel for delivery of an anti-proliferative agent, wherein the surface waves are propagated from the distal end of the vibrational device to the treatment area through irrigation liquid; positioning a blood flow protection device at a location distal to the treatment area to prevent the anti-proliferative agent from flowing distally; delivering the anti-proliferative agent to the treatment area using a contrast agent as a matrix within less than 60 minutes from the application of the surface waves; and applying the therapeutic agent in the treatment area for less than 60 minutes.