Patent ID: 9513195
Filing Date: 2016-12-06
CPC Classification: B01L,C12M,G01N,G06K

Claim Text:
1. A system for capturing cells in single-cell format, comprising: an array defined on a broad face of a substrate, comprising: a plurality of pores, each pore in the plurality of pores displaced from at least one other pore in the plurality of pores and comprising: a chamber having an upstream end configured to accept a single cell, and a pore channel, fluidly coupled to the chamber at a downstream end of the chamber, defined by a pore channel width configured to block egress of the single cell, wherein each chamber of the plurality of parallel pores is physically coextensive with an adjacent chamber by a barrier configured to substantially block fluid flow in a direction parallel to fluid flow through the pore channel; an inlet channel directly fluidly coupled to the upstream end of each chamber of the plurality of pores; and an outlet channel fluidly coupled to each pore channel of the plurality of pores, wherein flow from the inlet channel is configured to reach the outlet channel only by way of the plurality of pores; an inlet manifold, defined on the broad face of the substrate, fluidly coupled to the inlet channel of the array; and an outlet manifold, defined on the broad face of the substrate, fluidly coupled to the outlet channel of the array.