Patent ID: 9375425
Filing Date: 2016-06-28
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A composition comprising an antibody antagonist to c-Met, or a cMet-binding fragment thereof, and an aminoheteroaryl compound, wherein: i) said antibody antagonist to c-Met comprises a heavy chain comprising CDR-H1, CDR-H2 and CDR-H3 comprising, respectively, the amino acid sequences SEQ ID Nos. 7, 8, and 9; and a light chain comprising CDR-L1, CDR-L2 and CDR-L3 comprising, respectively, the amino acid sequences SEQ ID Nos. 15, 16, and 17; and ii) said aminoheteroaryl compound is selected from the group consisting of compounds of formula I: R each R each R each R each R each R R each R each m is independently 0, 1 or 2; each n is independently 0, 1, 2, 3 or 4; each p is independently 1 or 2; and a pharmaceutically acceptable salt, hydrate or solvate thereof.