Patent ID: 9494571
Filing Date: 2016-11-15
CPC Classification: C12Q,G01N

Claim Text:
1. A process for testing in production of a biologic for the presence of a first viral pathogen in a biological sample obtained from a cell culture, the process comprising the steps of: (i) providing a sample obtained from the cell culture for production of the biologic from a second virus; (ii) contacting the sample with an inhibitory agent, wherein said agent is an oligomeric compound that binds through complementary base pairing to a nucleotide sequence present in, encoded by and/or transcribed from the genome of the second virus, and the second virus is known to be present in the sample; (iii) incubating the sample obtained from the cell culture under conditions that permit the reproduction of said first viral pathogen; and (iv) testing material arising from step (iii) for said first viral pathogen by microscopy, a reverse transcription-based biochemical test for retroviruses, detection of a cytopathic effect, a PCR-based molecular genetic test, an animal inoculation test, infection of embryonated eggs, or any combination thereof.