Patent ID: 9439970
Filing Date: 2016-09-13
CPC Classification: A61K,A61P,B01F,C07D

Claim Text:
1. A solid dispersion, comprising: 10 to 50 wt % carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester, or a pharmaceutically acceptable salt thereof, 45 to 85 wt % water-soluble polymer having a glass transition temperature lower than the melting point of carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester, and 1 to 5 wt % plasticizer, wherein the solid dispersion is prepared by melt extrusion, wherein the water-soluble polymer is selected from polyvinylpyrrolidone, hypromellose acetate succinate and a combination thereof, and wherein the plasticizer is selected from the group consisting of D-alpha-tocopheryl polyethylene glycol 1000 succinate, polyethylene glycol 400, and a combination thereof.