Patent ID: 9278144
Filing Date: 2016-03-08
CPC Classification: A61K,C07K,G01N

Claim Text:
1. A selective delivery molecule of Formula I, having the structure: wherein, X is a peptide linker cleavable by a matrix metalloproteinase; A is a peptide with a sequence comprising a series of 5 glutamates (SEQ ID NO:5); B is a peptide with a sequence comprising a series of 8 arginines (SEQ ID NO:6); c M is a polyethylene glycol (PEG) polymer; and D wherein [c M -M] is bound to at any position on X, [D A -c A ] is bound to any amino acid on A, [c B -D B ] is bound to any amino acid on B, and M is a PEG polymer having an average molecular weight of 500 Da to 10 kDa.