Patent ID: 9376479
Filing Date: 2016-06-28
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A composition comprising a crystal of human growth hormone (hGH), and polyarginine wherein said crystal of hGH is crystallized from a solution free of polyarginine and is soaked in polyarginine, and wherein said crystal of hGH comprises at least one cation and hGH which is selected from the group consisting of: (a) the 191 amino acid sequence of native hGH (SEQ ID NO:1); and (b) the 192 amino acid sequence of somatrem consisting of said 191 amino acid sequence of native hGH (SEQ ID NO:1) and an additional N-terminal methionine, and wherein said hGH is present in a hGH:polyarginine ratio of 5:1 (w/w) to 40:1 (w/w).