Patent ID: 9359405
Filing Date: 2016-06-07
CPC Classification: A61K,A61P,C07K,Y02A

Claim Text:
1. A multimeric compound consisting of, i) two or more peptides wherein each of said two or more peptides consists of 10 to 14 consecutive amino acid residues derived from IL-1 receptor antagonist protein (IL1RA), each peptide: consisting of the amino acid sequence of SEQ ID NO:1 and optionally additional amino acid residues up to a total length of 11 to 14 amino acid residues; or consisting of a variant of SEQ ID NO:1 having at least 90% identity to SEQ ID NO:1, said variant comprising one conservative amino acid substitution, and optionally additional amino acid residues up to a total length of 11 to 14 amino acid residues; wherein each peptide is capable of binding to IL-1 receptor type 1 (IL1RI), and capable of interfering with the binding of IL-1 to IL1RI, and ii) optionally one or more linker groups.