Patent ID: 9381256
Filing Date: 2016-07-05
CPC Classification: A61K,A61P,C07D,C07K

Claim Text:
1. A compound represented by any one of the following formulas: or a pharmaceutically acceptable salt thereof, wherein: the double line Y is selected from —H, —OR, —OCOR′, —SR, —NR′R″, —SO R is —H, an optionally substituted linear, branched or cyclic alkyl, alkenyl or alkynyl having from 1 to 10 carbon atoms or a PEG group —(CH R′ and R″ are the same or different, and are selected from —H, —OR, —NRR X′ is selected from the group consisting of —H, —OH, an optionally substituted linear, branched or cyclic alkyl, alkenyl or alkynyl having from 1 to 10 carbon atoms, phenyl, and an amine-protecting group; Y′ is selected from the group consisting of —H, an oxo group, an optionally substituted linear, branched or cyclic alkyl, alkenyl or alkynyl having from 1 to 10 carbon atoms; R′ is a linear or branched alkylene having 1 to 6 carbon atoms, optionally substituted with a charged substituent or an ionizable group Q; R G is selected from —CH— or —N—; Z wherein: q is an integer from 1 to 5; R n′ is an integer from 2 to 6; U is —H or —SO M is —H or a cation.