Patent ID: 9518251
Filing Date: 2016-12-13
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method for enhancing the therapeutic effect of stem cells on autoimmune diseases, cardiovascular diseases, and/or hematological diseases, comprising: a) pre-treating the stem cells by culturing the stem cells in a culture medium comprising 0.1 μg/ml to 20 μg/ml of ligustilide to increase the expression of differentiation-promoting genes in the stem cells, increase the expression of homing-promoting genes in the stem cells, and/or decrease the expression of inflammatory genes in the stem cells, wherein the culture medium does not comprise insulin; and b) administering an effective amount of stem cells pre-treated in step a) to a subject suffering from autoimmune diseases, cardiovascular diseases and/or hematological diseases.