Patent ID: 9249469
Filing Date: 2016-02-02
CPC Classification: C12Q

Claim Text:
1. A method for determining the status and/or the response of the immune system in a subject having or suspected of having colon cancer, comprising the steps of: (i) determining an expression profile of a set comprising at least two miRNAs representative for the status and/or the response of the immune system in a blood cell sample from a subject, wherein the blood cell sample is a blood cellular fraction consisting of a mixture of red blood cells, white blood cells, and platelets; (ii) comparing said expression profile to a reference, wherein the comparison of said expression profile to said reference allows for determining the status and/or the response of the immune system in said subject; and, (iii) determining the status and/or response of the immune system in the subject to diagnose whether the subject has colon cancer; wherein the miRNAs comprised in the set are selected from the group consisting of SEQ ID NO: 1-588, a fragment thereof, and a sequence having at least 80% sequence identity thereto.