Patent ID: 9376417
Filing Date: 2016-06-28
CPC Classification: C07C,C07D

Claim Text:
1. A process for preparing a compound of formula (III) in which Ar is a group, where R the Ar radical may additionally also be a heteroaromatic radical or the Ar radical may also be 1- or 2-naphthyl, and R where R wherein an aryl or heteroaryl halide of formula (I) in which Hal is chlorine, bromine or iodine and Ar is as defined above, is reacted with a malonic ester of formula (II) in the presence of a palladium catalyst, of a phosphine ligand and of a mixture of inorganic bases, without using caesium carbonate or caesium bicarbonate, wherein the mixture of inorganic bases comprises potassium carbonate and potassium bicarbonate in a ratio of 1:1, optionally using an organic solvent.