Patent ID: 9522218
Filing Date: 2016-12-20
CPC Classification: A61L,A61P,C08B,C08J,C12N

Claim Text:
1. A method for preparing a porous scaffold which consists of the following steps: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide selected from the group consisting of dextran, agar, pullulan, inulin, heparin, fucoidan, and mixtures thereof; an amount of a covalent cross-linking agent selected from the group consisting of trisodium trimetaphosphate (STMP), phosphorus oxychloride (POCl b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide; c) submerging said hydrogel into an aqueous acidic solution to form pores; and d) washing the porous scaffold obtained at step c), wherein the porous scaffold is a hydrogel; the porogen agent is dissolved in step a); the weight ratio of the polysaccharide to the porogen agent is in the range from 6:1 to 1:1; and wherein the alkaline aqueous solution in a) does not include a surfactant.