Patent ID: 9272030
Filing Date: 2016-03-01
CPC Classification: A61K,C07K

Claim Text:
1. A method of treating, reducing the risk, lessening the severity or delaying outset of an amyloidogenic disease characterized by amyloid deposits of Aβ in the brain in a population of patients, comprising: administering different regimes to different patients in the population depending on the number of alleles of ApoE4 present in the patients; wherein at least one of the regimes comprises administering an antibody to Aβ to a patient; wherein response to treatment of patients receiving the antibody to Aβ is monitored by determining CSF levels of phospho or total tau before and after initiating a regime involving administration of the antibody, a reduction after initiating the regime in a patient providing an indication the regime is effective in the patient.