Patent ID: 9492315
Filing Date: 2016-11-15
CPC Classification: A61F,A61K,A61P

Claim Text:
1. An ophthalmic drug delivery system comprising: a formulation comprising a therapeutic agent that is an inhibitor of complement factor D, the therapeutic agent having a concentration in a solution volume; an extended release device configured to be implanted in an eye, the device comprising: an injector configured to penetrate the penetrable barrier while the device is implanted in the eye to refill or flush the reservoir through the penetrable barrier of the access port with an amount of the formulation, the injector comprising: a needle having a first lumen and a second lumen; an injection chamber configured to be in one-way fluid communication with the reservoir via the first lumen; and a vent chamber configured to be in one-way fluid communication with the reservoir via the second lumen, wherein the vent chamber comprises a resistance to flow substantially lower than a resistance to flow through the rigid porous structure.