Patent ID: 9345664
Filing Date: 2016-05-24
CPC Classification: A61K

Claim Text:
1. A process for preparing a dry powder inhaler containing an inhalable medicament comprising the steps of: (a) forming a plurality of loose agglomerates of a pharmaceutically active ingredient by passing the pharmaceutically active ingredient through a sieve having a mesh of 50-3000 μm, wherein the loose agglomerates are not spheronized; (b) combining the plurality of loose agglomerates obtained from step (a) with a pharmaceutically acceptable particulate carrier; (c) mixing the resultant material from step (b) in a mixer outside of an inhaler to break up the loose agglomerates into primary particles of the pharmaceutically active ingredient and to disperse the primary particles in the pharmaceutically acceptable particulate carrier such that 90% or more of the pharmaceutically active ingredient has a particle size of 50 μm or less to provide the inhalable medicament; and (d) filling the inhalable medicament from step (c) into the reservoir of a dry powder inhaler.