Patent ID: 9493435
Filing Date: 2016-11-15
CPC Classification: A61P,C07C,C07D

Claim Text:
1. A compound having a structural formula (1c): or a pharmaceutically acceptable salt thereof, wherein R6 is: wherein R9 and R10, together with the nitrogen atom to which they are attached, form a 5-membered or a 6-membered saturated heterocycle containing 1 or 2 N, substituted with C1-C6 alkyl or (b) furyl substituted with wherein (a) R9 and R10 independently are C1-C6 alkyl or (b) R9 and R10, together with the nitrogen atom to which they are attached, form a 6-membered saturated heterocycle having 2 nitrogen atoms; (c) pyrimidinyl substituted with in which R9 and R10, together with the nitrogen atom to which they are attached, form a 6-membered saturated heterocycle having 2 nitrogen atoms; (d) thiazolyl substituted with C1-C6 alkyl or wherein (a) R9 and R10 independently are hydrogen or C1-C6 alkoxyl C1-C6 alkyl or (b) R9 and R10, together with the nitrogen atom to which they are attached, form a 5-membered saturated ring containing one nitrogen atom or a 6-membered saturated heterocycle containing 1 or 2 heteroatoms selected from nitrogen and oxygen; (e) oxazolyl substituted with wherein (a) R9 and R10 independently are hydrogen or C1-C6 alkyl or (b) R9 and R10, together with the nitrogen atom to which they are attached, form a 6-membered heterocycle containing two nitrogen atoms; (f) triazolyl substituted with C1-C6 alkoxyl C1-C6 alkyl or wherein R10 is C1-C6 alkyl; or wherein (a) R9 and R10 independently are C1-C6 alkyl or (b) R9 and R10, together with the nitrogen atom to which they are attached, form a 6-membered saturated heterocycle containing the nitrogen atom and one oxygen atom.