Patent ID: 9297813
Filing Date: 2016-03-29
CPC Classification: A61K,A61P,C12N,C12Q,G01N

Claim Text:
1. A method for inhibiting cell proliferation of human lung cancer cells or human colon cancer cells in vivo, comprising contacting the human lung cancer cells or the human colon cancer cells in vivo with an inhibitor of glycine dehydrogenase (GLDC) expression or activity, wherein the GLDC has a nucleic acid sequence set forth in SEQ ID NO: 1 or an amino acid sequence set forth in SEQ ID NO: 2, wherein the inhibitor is in an amount effective for inhibiting cell proliferation of the human lung cancer cells or the human colon cancer cells, and wherein the GLDC inhibitor comprises a small interfering RNA that comprises a nucleotide sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8 and SEQ ID NO: 9.