Patent ID: 9415069
Filing Date: 2016-08-16
CPC Classification: A61K,A61P,C12N

Claim Text:
1. A method of obtaining an immunosuppressive myeloid-derived dendritic cell, the method comprising obtaining a precursor cell that is capable of differentiating into a myeloid-derived dendritic cell, wherein the precursor cell is a myeloid precursor cell; and culturing the precursor cell in a medium that contains GM-CSF and GRO-γ or GRO-α for a sufficient period of time to allow the precursor cell to differentiate to a myeloid-derived dendritic cell, wherein the myeloid-derived dendritic cell exhibits an immunosuppressive phenotype, thereby obtaining the immunosuppressive myeloid-derived dendritic cell, wherein the precursor cell and the myeloid-derived dendritic cell are not co-cultured with a mesenchymal stem cell (MSC), the precursor cell is a human CD14