Patent ID: 9526915
Filing Date: 2016-12-27
CPC Classification: A61K,A61N,C07D

Claim Text:
1. A method of inhibiting proliferation or inducing apoptosis of a cancer cell in a human subject which overexpresses TCTP comprising administering to the subject a) a compound, wherein the compound has the structure or a salt, enantiomer or zwitterion of the compound, in an amount effective to inhibit the proliferation or to induce apoptosis of the cancer cell, and b) an anti-cancer agent in an amount effective to inhibit the proliferation or to induce apoptosis of the cancer cell, wherein the cancer is selected from adrenocortical cancer, bladder cancer, osteosarcoma, cervical cancer, esophageal, gallbladder, head and neck cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, renal cancer, melanoma, pancreatic cancer, rectal cancer, thyroid cancer, throat cancer, breast cancer, lung cancer and prostate cancer.