Patent ID: 9377403
Filing Date: 2016-06-28
CPC Classification: G01N

Claim Text:
1. A processor-implemented method for linear filtering of noise in a sensorgram generated from a surface plasmon resonance apparatus, the method comprising: generating and receiving a sensorgram from a surface plasmon resonance measurement apparatus; providing a linear filter of variable length to filter an output signal in the sensorgram; determining an optimal length of the linear filter based on a first optimal length of the linear filter based on a slope of the signal in the sensorgram and a second optimal length of the linear filter based on a locked interception linear error, LILE, detector, wherein the LILE detector is the Root Mean Square Error (RMSE) of an optimal determined linear curve compared to sensorgram data in a short window based on filter length of a prior iteration process, and wherein an intercept parameter in the optimal determined linear curve is forced to pass through prior filtered output values; applying the linear filter to the output signal in the sensorgram to generate a filtered sensorgram; and providing the filtered sensorgram to an output device.