Patent ID: 9499852
Filing Date: 2016-11-22
CPC Classification: A61K,C12Q

Claim Text:
1. A method of diagnosing an infection with a pathogenic bacterial stain from a S. aureus strain or a P. aeruginosa strain, comprising a) contacting the infected area with a lipid bilayer vesicle comprising 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), and a sterol, wherein the lipid bilayer vesicle comprises between 40 and 65% DPPC and DPPE, and said lipid bilayer vesicle encapsulating a signaling molecule, wherein upon contact, said pathogenic bacterial strain lyses the lipid bilayer vesicle to releasing the signaling molecule from said lysed lipid bilayer vesicle; b) producing a visualizable colorimetric or fluorescent signal from said released signaling molecule, thereby indicating the presence of an infection; and, c) detecting said visualizable colorimetric or fluorescent signal.