Patent ID: 9347934
Filing Date: 2016-05-24
CPC Classification: G01N

Claim Text:
1. A method for identifying a compound that inhibits the bitter taste due to KCl, comprising: a) providing a first and a second cell, wherein said first and second cell express one or more bitter taste receptors selected from the group consisting of: TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R44 and TAS2R60, wherein said first and second cell express the same one or more bitter taste receptors; b) contacting said first cell with a tastant, wherein the tastant activates the one or more bitter taste receptor; c) contacting said second cell with a test compound and the tastant; d) assaying said first and second cells for bitter taste receptor activation; and e) comparing the bitter taste receptor activation of said first cell to the bitter taste receptor activation of said second cell, wherein the test compound is an inhibitor of bitter taste due to KCl, if bitter taste receptor activity of said second cell is less than the bitter taste receptor activity of said first cell, and wherein the tastant is KCl.