Patent ID: 9393289
Filing Date: 2016-07-19
CPC Classification: A61K,A61P

Claim Text:
1. A method of treatment or prophylaxis for a bleeding disorder, the method comprising: administering to a patient in need thereof a first pharmaceutical composition comprising Factor VIII by a non-intravenous route, wherein the Factor VIII is administered at a dose ranging from about 50 IU/kg body weight to about 800 IU/kg body weight; and administering a second pharmaceutical composition comprising a sulfated glycosaminoglycan by a non-intravenous route, wherein the sulfated glycosaminoglycan is administered at a dose ranging from about 0.001 to about 100 mg per mL product applied, wherein the administered dosage of the Factor VIII and the sulfated glycosaminoglycan are sufficient to maintain a blood plasma level in the patient of more than 2% of the normal plasma level of Factor VIII in a healthy subject during a period from 1 hour after administration to 48 hours after administration, wherein the non-intravenous route is selected from the group consisting of subcutaneous, intramuscular, intraperitoneal, intradermal or transdermal administration, thereby providing treatment or prophylaxis for the bleeding disorder.