Patent ID: 9316633
Filing Date: 2016-04-19
CPC Classification: G01N

Claim Text:
1. A method for treating a disease or disorder associated with a urea clearance insufficiency in a subject, said method comprising administering to the subject a composition comprising a pharmaceutically suitable excipient and a compound that inhibits transport of urea by the urea transporter across a cell membrane, wherein the compound is selected from N-benzyl-4-(4-chlorophenylsulfonyl)-2-(2-fluorophenyl)oxazol-5-amine; 5-(methylthio)-4-(phenylsulfonyl)-2-p-tolyl-1H-imidazole; 2-phenyl-4-tosyl-1H-imidazole-5-thiol; and S-2-phenyl-4-(phenylsulfonyl)-1H-imidazol-5-yl benzothioate.