Patent ID: 9340582
Filing Date: 2016-05-17
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A bioconjugate or a multimer thereof, comprising: a) a peptide or polypeptide having the following formula V (SEQ ID NO: 6): wherein: X1 is the N-terminus of the polypeptide and is either absent or is selected from R, Q, A and K; X5 is L, A, K, D or F; wherein the side chain of the two Cysteines (C) are linked together via a covalent bond forming a disulfide (—S—S—); X7 is H, A, K, F, P, N or E; X11 is M, A, F, Y, L or K; and X13 is the C-terminus and is absent or is selected from F, I, A, K, H and E; or an amide, an ester or a salt of the polypeptide; and wherein the half-life extending moiety is a Fc domain which is fused to said polypeptide via a linker and wherein the linker has the following Formula: -[GGGGS]n-, n is 1, 2 or 3 (SEQ ID NO: 16) or the linker is GG or GS.