Patent ID: 9415353
Filing Date: 2016-08-16
CPC Classification: A61L,B01D

Claim Text:
1. A process for forming a virus-retentive ultrafiltration membrane having an improved flux, the process comprising the steps of: (a) providing a multilayer substrate membrane comprising at least one microporous layer and an ultrafiltration layer; (b) contacting the substrate membrane with a solution of hydroxypropyl cellulose to adsorb said hydroxypropyl cellulose onto the substrate membrane; (c) removing excess hydroxypropyl cellulose from the substrate membrane by rinsing in water; and (d) subjecting the rinsed substrate membrane to a step selected from the group consisting of: (1) autoclaving in the presence of steam or water; and (2) submerging in boiling water, thereby to form a virus-retentive ultrafiltration membrane having an improved flux relative to a membrane not subjected to step (d) subsequent to optionally rinsing in water, and further wherein the membrane has log reduction value (LRV) for Phi X174 of at least 4.0 and a throughput of 1000 L/m