Patent ID: 9457052
Filing Date: 2016-10-04
CPC Classification: A61K,C12N

Claim Text:
1. A transplantation method comprising inducing allograft tolerance and chimerism by: a) administering, intravenously, subcutaneously, or intradermally, to a host one or more doses of human stem/progenitor-like cells, wherein said human stem/progenitor-like cells are adipose-derived stem cells isolated from fresh human subcutaneous adipose lipoaspirate; b) administering, intravenously, subcutaneously or intradermally, to a host, donor cells, wherein said donor cells are allogeneic to the host, and wherein said donor cells are unprocessed bone marrow, or low density bone marrow cells, wherein said donor cells are administered up to ten (10) days after administration of said human stem/progenitor-like cells in step (a); c) transplanting tissue, allogenic to the host but autologous to the donor cells up to ten (10) days before or after administration of said human stem/progenitor cells; and d) depleting of CD4+ and CD8+ cell of the host; and e) administering a nonmyeloablative anti-neoplastic agent.