Patent ID: 9517306
Filing Date: 2016-12-13
CPC Classification: A61M,G16H

Claim Text:
1. Apparatus for the delivery of insulin, the apparatus comprising: a) a glucose monitor adapted to measure respective glucose levels of a subject at discrete time intervals and provide respective glucose measurement data indicating each measured glucose level; b) an insulin infusion pump configured to deliver insulin in response to a delivery control signal; c) a memory configured to store a plurality of basal insulin delivery amounts at respective ones of the discrete time intervals; and d) a model predictive controller adapted to, for each of a plurality of the discrete time intervals: e) in which the model predictive controller is adapted to determine the insulin delivery amount by mathematical minimization of a cost function that computes a cost metric correlated with physiological-fluid glucose-level excursions from a selected target glucose range for a particular set of n successive candidate insulin delivery amounts beginning from the selected one of the time intervals, and the model predictive controller, in order to carry out the mathematical minimization, is adapted to: f) and further in which the model predictive controller is adapted to, in order to compute the cost function for each input set of n successive candidate insulin delivery amounts: g) deliver, with the insulin infusion pump, the determined insulin delivery amount of insulin to the subject, as provided by the delivery control signal from the controller.