Patent ID: 9234886
Filing Date: 2016-01-12
CPC Classification: A61K,C12Q,G01N

Claim Text:
1. A method for treating autoimmune diabetes in a vertebrate patient, said method comprising the steps of: (a) assaying T cells from the patient for a patient level of roundabout axon guidance receptor homolog 1 (ROBO1) expression as compared with a mean level of ROBO1 expression for non-diabetic, conspecific individuals; and determining if the patient level of ROBO1 expression is significantly higher than the non-diabetic mean level at a significance level of p<0.05; and (b) administering an SDF-1 agonist to the patient if the patient level of ROBO1 expression is significantly higher at a significance level of p<0.05 than the non-diabetic mean level of ROBO1 expression; wherein the SDF-1 agonist is CTCE-0214.