Patent ID: 9370584
Filing Date: 2016-06-21
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A method of treating a subject having a cancer expressing CA6 glycotope, said method comprising, administering a therapeutically effective amount of a conjugate to said subject, wherein said conjugate comprises a cell binding agent and a cytotoxic agent, wherein said cell binding agent comprises an antibody or epitope-binding fragment thereof comprising at least one heavy chain variable region and at least one light chain variable region, wherein said heavy chain variable region comprises three complementarity-determining regions having amino acids 31-35, 50-66, and 99-106 of SEQ ID NO:11, respectively, and wherein said light chain variable region comprises three sequential complementarity-determining regions having amino acids 24-33, 49-55, and 88-96 of SEQ ID NO:8, respectively, wherein the cell binding agent binds to the CA6 glycotope.