Patent ID: 9234028
Filing Date: 2016-01-12
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A polypeptide comprising a tenth fibronectin type III ( 10 Fn3) domain, wherein the 10 Fn3 domain (i) comprises an AB loop, a BC loop, a CD loop, a DE loop, an EF loop, and an FG loop, wherein the amino acid sequences of the BC, DE, and FG loops are identical to the amino acid sequences of the respective BC, DE, and FG loops of an 10 Fn3 domain with an amino acid sequence selected from the group consisting of SEQ ID NOs: 207-231; and (ii) binds human epidermal growth factor receptor (EGFR) with a disassociation constant of less than 10 −4 M.