Patent ID: 9372196
Filing Date: 2016-06-21
CPC Classification: C12N,G01N

Claim Text:
1. A bio-specimen reference standard method comprising: growing one or more cell lines in a medium containing a minor stable isotope therein such that proteins of the one or more cell lines are labeled with said minor isotope; characterizing a proteome of the one or more cell lines using the isotope-labeled proteins; before or after the characterizing, preserving the one or more cell lines having the proteins labeled with said minor isotope by fixation so as to form a bio-specimen reference standard; and after the preserving to form the bio-specimen reference standard: wherein the characterizing a proteome of the one or more cell lines is before the performing the mass spectrometry on the combined portions of the sample and the reference standard, and the characterizing the proteome of the one or more cell lines includes: