Patent ID: 9283192
Filing Date: 2016-03-15
CPC Classification: A61K,A61P,Y02A

Claim Text:
1. A press-coated tablet formulation for a delayed, followed by a prolonged release of an active agent, the press-coated tablet formulation comprising: (a) a core comprising the active agent together with a wax and optionally one or more fillers; and (b) a delayed release layer surrounding the core and comprising a wax and a low substituted hydroxypropyl cellulose in a ratio of 20:80 to 50:50 w/w; wherein the delayed release layer delays release of the active agent within the core for between 2-8 hours after administration of the press-coated tablet formulation to a subject and thereafter a prolonged release of the active agent from the core occurs, such that the active agent in the core is continuously released over a period of 2 up to 8 hours and wherein the low substituted hydroxypropyl cellulose is micronised with a mean particle diameter of 20 μm and has a molecular weight of 115,000 and a hydroxypropyl content of 8%.