Patent ID: 9505845
Filing Date: 2016-11-29
CPC Classification: A61K,A61P,C07K

Claim Text:
1. A method of treating a disease characterized by growth of tumor cells expressing PTK7, comprising administering to a subject a monoclonal antibody, or antigen-binding portion thereof, that specifically binds to human PTK7, wherein the antibody, or antigen-binding portion thereof, is linked to a therapeutic agent and comprises a heavy chain variable region CDR1 comprising SEQ ID NO:12; a heavy chain variable region CDR2 comprising SEQ ID NO:16; a heavy chain variable region CDR3 comprising SEQ ID NO:20; a light chain variable region CDR1 comprising SEQ ID NO:25; a light chain variable region CDR2 comprising SEQ ID NO:31; and a light chain variable region CDR3 comprising SEQ ID NO:37, in an amount effective to treat the disease, wherein the disease is lung cancer.