Patent ID: 9364465
Filing Date: 2016-06-14
CPC Classification: A61K,C07D

Claim Text:
1. Compounds of Formula (I) wherein: R is joined from the methylene moiety formed by reduction of the carboxylic acid of one of the following acids: cis,cis,cis-7,10,13-hexadecatrienoic acid (HTA), named as RS-5-((7Z,10Z,13Z)-hexadeca-7,10,13-trien-1-yl)thiazolidine-2,4-dione; cis,cis,cis-9,12,15-octadecatrienoic acid (ALA), named as RS-5-(9Z,12Z,15Z)-octadeca-6,9,12-trien-1-yl)thiazolidine-2,4-dione; cis,cis,cis,cis-6,9,12,15-octadecatetraenoic acid (SDA), named as RS-5-((6Z,9Z,12Z,15)-octadeca-6,9,12,15-tetraen-1-yl)thiazolidine-2,4-dione; cis,cis,cis-11,14,17-eicosatrienoic acid (ETE), named as RS-5-((11Z,14Z,17Z)-eicosa-11,14,17-triene-1-yl)thiazolidine-2,4-dione; cis,cis,cis,cis-8,11,14,17-eicosatetraenoic acid (ETA), named as RS-5-((8Z,11Z,14Z,17Z)-eicosa-8,11,14,17-tetraen-1-vi)thiazoliidine-2,4-dione; cis,cis,cis,cis,cis-5,8,11,14,17-eicosapentanenoic acid (EPA), named as RS-5-((5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaen-1-yl)thiazolidine-2,4-dione; cis,cis,cis,cis,cis-6,9,12,15,18-heneicosapentaenoic acid (HPA), named as RS-5-((6Z,9Z,12Z,15Z,18Z)-heneicosa-6,9,12,15,18-pentaen-1-yl)thiazolidine-2,4-dione: cis,cis,cis,cis,cis-7,10,13,16,19-docosapentaenoic acid (DPA), named as RS-5-((7Z,10Z,13Z,16Z,19Z)docosa-7,10,13,16,19-pentaen-1-yl)thiazolidine-2,4-dione; cis,cis,cis,cis,cis,cis-4,7,10,13,16,19-docosahexaenoic acid (DHA), named as RS-5-((4Z,7Z,10Z,13Z,16Z,19Z)docosa-4,7,10,13,16,19-hexaen-1-yl)thiazolidine-2,4-dione; cis,cis,cis,cis,cis-9,12,15,18,21-tetracosapentaeonic acid (TPA), named as RS-5-((9Z,12Z,15Z,18Z,21Z)-tetracosa-9,12,15,18,21-pentaen-1-yl)thiazolidine-2,4-dione; or cis,cis,cis,cis,cis,cis-6,9,12,15,18,21-tetracosahexaeonic acid (THA), named as RS-5-((6Z,9Z,12Z,15Z,18Z,21Z)-tetracosa-6,9,12,15,18,21-hexaen-1-yl)thiazolidine-2,4-dione.