Patent ID: 9410203
Filing Date: 2016-08-09
CPC Classification: C12Q,G01N,Y10T

Claim Text:
1. A method of detecting a CFTR mutation, comprising: (a) contacting a biological sample comprising a CFTR nucleic acid obtained from a human with a detectably labeled nucleic acid probe that specifically hybridizes to a mutant CFTR nucleic acid comprising a 4177delG deletion mutation, if present, but not to a wild-type CFTR nucleic acid, wherein the detectably labeled nucleic acid probe comprises a sequence of 8-20 nucleotides that is fully complementary to a portion of the mutant CFTR nucleic acid and comprises the 4177delG mutation: and (b) detecting the CFTR 4177delG deletion mutation when a hybrid is formed between the detectably labeled nucleic acid probe and the mutant CFTR nucleic acid.