Patent ID: 9320730
Filing Date: 2016-04-26
CPC Classification: A61K,A61P

Claim Text:
1. A method for administering a dose of a nitrogen mustard compound to a patient comprising the steps of a. contacting a stream of an intravenous infusion solution continuously flowing at a controlled rate with a stream of a second solution continuously flowing at a controlled rate and comprising the nitrogen mustard compound and either 1) polyvinylpyrrolidone and ethanol, or 2) mannitol and a solvent selected from the group consisting of dimethylsulfoxide, n-methyl-2-pyrrolidone, dimethylacetamide, polyethylene glycol, propylene glycol, glycerin, and mixtures thereof; b. mixing the solutions to provide a uniform and continuously flowing stream of a mixed solution which provides a pharmaceutical dose of 0.2 to 4.0 mg/ml of the nitrogen mustard compound; and c. administering the mixed solution to the patient, thereby administering the pharmaceutical dose of the nitrogen mustard compound to the patient, wherein the residence time period of the solutions from contacting to administering is 30, 20, 10, or 5 seconds or less.