Patent ID: 9408927
Filing Date: 2016-08-09
CPC Classification: A61K,A61P

Claim Text:
1. A method of imaging at least a portion of the central nervous system (CNS) in a subject, comprising: administering to the subject a contrast agent having a structure as in Formula (II), wherein: J is selected from N(R K and L, when present, are independently selected from hydrogen, alkoxyalkyl, alkyloxy, aryl, alkyl, heteroaryl, and an imaging moiety, each of which is optionally substituted; M is selected from alkoxyalkyl or alkyloxy, each of which is optionally substituted, or L and M, together with the atom to which they are attached, form a ring, optionally substituted; Q is halo or haloalkyl; n is 0, 1, 2, or 3; R R Y is carbon or oxygen; provided that when Y is oxygen, K and L are absent and M is alkoxyalkyl, optionally substituted, wherein at least one imaging moiety is present in Formula (II); and scanning the subject using diagnostic imaging to produce an image of at least a portion of the CNS.