Patent ID: 9259460
Filing Date: 2016-02-16
CPC Classification: A61K,A61P,Y02A

Claim Text:
1. A liquid combination vaccine comprising antigens for protecting a subject against at least diphtheria (‘D’), tetanus (‘T’), pertussis (‘P’) and Haemophilus influenzae type b (‘Hib’), wherein: (a) the antigen for protecting against Hib is a conjugate of a Hib capsular saccharide; (b) the concentration of the Hib conjugate in the vaccine is <15 μg/ml; (c) the vaccine comprises an aluminium phosphate adjuvant; (d) no more than 15% by weight of the Hib conjugate in the vaccine is adsorbed to aluminium phosphate; (e) the vaccine does not contain an aluminium hydroxide adjuvant; (f) the vaccine does not contain an aluminium potassium sulphate adjuvant; and (g) the vaccine contains an Al 3+ concentration of 0.1-1.0 mg/ml.