Patent ID: 9259439
Filing Date: 2016-02-16
CPC Classification: A61K,A61L

Claim Text:
1. A dual-phase bone and dental repair biocompatible, bioresorbable, calcium phosphate cement precursor system, said system comprising at least a first discrete aqueous phase and a second discrete nonaqueous phase which in combination are capable of reacting to form a cement with a setting time of between about 1 minute and 20 minutes and the phases have a shelf life of 7 days or more, said first phase consisting essentially of one or more first calcium compounds and further consisting of one or more carboxyl compounds selected from the group consisting of a carboxylic acid and a carboxylate, said second phase consisting essentially of one or more second calcium compounds which are all different from the first phase calcium compounds, at least one of said first and second phase calcium compounds consisting of a phosphate compound, said first and second phases being unmixed, and said first and second phases in combination characterized as cement precursors by reaction between said first phase compounds and second phase compounds to form said biocompatible, bioactive, bioresorbable cement upon mixing, each of said discrete first and second phases consisting essentially of a stable, non-hardenable paste prior to mixing, said first phase having a pH sufficiently acidic to preclude dissociation of said carboxyl compounds prior to mixing with said second phase.