Patent ID: 9522344
Filing Date: 2016-12-20
CPC Classification: B01D,B01L,G01N

Claim Text:
1. A method of exchanging fluids with suspended particles comprising: providing a microfluidic device comprising a first inlet channel operatively coupled to a source of particles suspended in a fluid; a second inlet channel operatively coupled to an exchange fluid; a linear and longitudinally symmetrical transfer channel having a proximal end and a distal end, the proximal end of the transfer channel connected to the first inlet channel and the second inlet channel; and first and second outlet channels connected to a distal end of the transfer channel; flowing the source of particles suspended in a fluid at a first flow rate into the first inlet channel; flowing the exchange fluid at a second flow rate into the second inlet channel wherein the ratio of the second flow rate to the first flow rate is at least 1.5; equilibrating the particles from the source of particles suspended in the fluid at an equilibrium position (X collecting the equilibrated particles in the first outlet channel; and collecting fluid substantially free of the equilibrated particles in the second outlet channel.