Patent ID: 9395355
Filing Date: 2016-07-19
CPC Classification: G01N,G16B

Claim Text:
1. A method for assessing in vitro a balance and an overall dynamic of bone metabolism wherein balance refers to a status of-bone metabolism as a result of two complementary and/or counter-acting biochemical processes, and overall dynamic refers to a magnitude of the status of bone metabolism, the method comprising: a) measuring a first biochemical marker representing a first biochemical process associated with bone metabolism to yield a result; b) measuring a second biochemical marker representing a second biochemical process associated with bone metabolism to yield a result, wherein measurements obtained from a) and b) are presented in the form of a vector; c) calculating a ratio of the results obtained in (a) and (b) to yield a slope of the vector; d) calculating a square value of the result from (a) and a square value of the result from (b), adding the square values to yield a sum, and calculating the square root of the sum to yield a length of the vector; wherein the ratio calculated in (c) is used to assess the balance of bone metabolism and wherein the square root calculated in (d) is used to assess the overall dynamic of bone metabolism.