Clue: Like victim of Heracles, one topped with shaggy mane (6)
Answer: NEMEAN
Explanation: Definition: Like victim of Heracles
ONE "topped", i.e. less its first letter + MANE*. I originally thought Azed had slipped up here, intending MANE* + AN. Killing the Nemean Lion was the first of the Labours of Heracles (aka Hercules)