Clue: Wretchedly triste, Danaë may appear so? (11)
Answer: TEARSTAINED
Explanation: Definition: Wretchedly triste, Danaë may appear so
(TRISTE DANAE)* &lit. Danaë is a character from Greek mythology, the mother of Perseus, who fulfilled a prophecy that he would kill Danaë's father, which presumably she wasn't happy about