Clue: Everyman's run into lav: behold, Everyman's in a muddle (9)
Answer: IMBROGLIO
Explanation: Definition: a muddle
A charade of I'M ('Everyman's') plus BROG, an envelope ('into') of R ('run') in BOG ('lav', slang for a toilet) plus LIO, another envelope ('in') of I ('Everyman') in LO (and 'behold').