Clue: 'Following ladies sleep around' sounds like a witty comment? (4,5,6)
Answer: NEXT SLIDE PLEASE
Explanation: Definition: sounds like a witty comment
A charade of NEXT ('following') plus SLIDE PLEASE, an anagram ('around') of 'ladies sleep'. The definition seems to refer to again, but I have not come across the clip before, and am not sure of its context.