Clue: Primarily, trendy educational disquisition to advance latest knowledge? (3,4)
Answer: TED TALK
Explanation: Primarily, trendy educational disquisition to advance latest knowledge? (3,4)
First letters ('primarily') of '**T**rendy **E**ducational **D**isquisition **T**o **A**dvance **L**atest** K**nowledge', with a fairly accurate &lit .