Clue: Paris saloon car runs over unknown Yankee on heroin (5,5)
Answer: CRAZY HORSE
Explanation: Definition: Paris saloon

*(car) [anag:runs} over Z (unknown, in mathematics) + Y (Yankee) on HORSE ("heroin")
 
*Le Crazy Horse Saloon is a renowned entertainment venue in Paris where nude dancers alternate with variety performers, especially magicians.