Clue: At first, Megan upset Harry, throwing away a gift of perfume (5)
Answer: MYRRH
Explanation: Definition: gift of perfume
A charade of M ('at first **M**egan') plus YRRH, an anagram ('upset') of 'H[a]rry', minus the A ('throwing away a'). If the surface brings to mind the Duchess of Sussex, she spells her name Meghan. We three kings of orient are.