Clue: A setter enthralling foremost of newspapers? (5)
Answer: ANGEL
Explanation: Definition: A setter
 A + GEL(setter/a liquid substance that sets/turns into a semi-solid state) **contained in**(enthralling) **1st letter of**(foremost of) "newspapers".
Defn: Name of … of crosswords in The Independent (which some might say is the foremost of newspapers).