Clue: One departure after another for Spaniard (5)
Answer: DIEGO
Explanation: One departure after another for Spaniard (5)
**DIE** + **GO** ("one departure after another") 
*Not sure if this works as *die* and *go* are both verbs, and *departure* is a noun (perhaps "One to depart after another Spaniard" may have been better, if a little clumsier?)