Clue: Daughter revered by Shiites, one cuddled by big mummy (6)
Answer: FATIMA
Explanation: Definition: Daughter revered by Shiites
**I** ("one") *cuddled by* **FAT** ("big") + **MA** ("mummy") 
*Fatima (normally spelt Fatimah) was the youngest daughter of the prophet Mohammed, although Shiites believe she was his only child.