Clue: One from among notables worsted – such as Brutus? (7)
Answer: NOBLEST
Explanation: Definition: such as Brutus?
***(notbles)** [anag:*worsted*] where NOTBLES is NOT(a)BLES with A ("one") *removed* 
 
 
*In Shakespeare's *Julius Caesar, *Marc Anthony describes Brutus as "the noblest Roman of them all".