### Clue: Reduce with diet pill oddly taken every Tuesday evening to begin with (7)
### Answer: DEPLETE 
 ### Explanation: Definition: Reduce
**D**(i)**E**(t)**P**(i)**L**(l) [*oddly*] *taken with* **E**(very) **T**(uesday) **E**(vening) [*to begin with*]