### Clue: Speechless Donald Trump's inside, powerless and adrift without lead from business? (10)
### Answer: DUMBSTRUCK 
 ### Explanation: Definition: Speechless
(Donald) **DUCK** with ***(trums)** *inside*, *without* [*lead from*] **B**(usiness) 
*UMSTR is an anagram of Trump's without P (powerless)