### Clue: One hostile to Officer Commanding carry-on, say? (10)
### Answer: ICONOCLAST 
 ### Explanation: One hostile to Officer Commanding carry-on, say? (10)
**I** (one) + **CON** (hostile to) + **O**(fficer) **C**(ommanding) + **LAST** (carry on) (an &lit. clue)