Patent ID: 11945839
Assignee: HOFFMANN-LA ROCHE, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 3:
4. The method according to claim 2, wherein the HIC medium is selected from the group consisting of:
(i) an HIC medium having an average particle size of about 34 μm, having butyl groups as ligands, having a ligand density of about 50 μmol/ml medium, having a binding capacity of about 39 mg BSA/ml medium, and comprising a matrix of cross-linked agarose;
(ii) an HIC medium having an average particle size of about 40 μm, having butyl groups as ligands, having a binding capacity of about 37 mg BSA/ml medium, and comprising a matrix of cross-linked agarose;
(iii) an HIC medium having an average particle size of about 40 μm, having phenyl groups as ligands, having a ligand density of about 9 μmol/ml medium, having a binding capacity of about 19 mg BSA/ml medium, and comprising a matrix of cross-linked agarose; and
(iv) an HIC medium having an average particle size of about 65 μm, having PPG groups as ligands, and comprising a matrix of cross-linked polymethylmethacrylate.