Patent ID: 11905533
Assignee: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  B | IPC C

Claim 0:
1. A modified adeno-associated virus (AAV) capsid protein comprising an insertion of a polypeptide at a position between amino acids corresponding to amino acids 588 and 589 of AAV9, wherein the polypeptide is selected from the group consisting of:
a) PB5-3 (SEQ ID NO:133);
b) PB5-5 (SEQ ID NO:134);
c) PB5-14 (SEQ ID NO:135);
d) Angiopep-2 (SEQ ID NO:181);
e) glutathione (GSH);
f) ApoE (159-167)2 (SEQ ID NO:138);
g) Leptin 30 (61-90) (SEQ ID NO:141); and
h) THR (SEQ ID NO:139).