Patent ID: 11858961
Assignee: AGILENT TECHNOLOGIES, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 10:
11. A kit for denaturing and deglycosylating a glycoprotein or glycopeptide of interest in vitro, said solution comprising (A) an ammonium cation sulfate or sulfonate detergent comprising (a) an aliphatic chain of 8-24 carbons, (b) a sulfate or sulfonate anion and (c) a tertiary or quaternary ammonium cation, wherein said aliphatic chain is covalently attached to said anion, and (B) a reductant, an alkylant, an additional organic solvent denaturant, an additional detergent, a chaotrope, or a combination of any of these.