Patent ID: 11938183
Assignee: THE JOHNS HOPKINS UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC A  C  G | IPC A  C  G

Claim 0:
1. A method for identifying one or more antibodies that inhibit a cancer cell in vitro, the method comprising:
isolating blood from a subject afflicted with scleroderma;
purifying the one or more antibodies from the blood;
assaying in vitro the growth, viability, or mobility of a cancer cell in the presence of the one or more antibodies, wherein a reduction in the growth, viability, or mobility of the cancer cell in the presence of the one or more antibodies, as compared to the growth, viability or mobility of the cancer cell in the absence of the one or more antibodies, identifies the one or more antibodies as inhibiting the cancer cell;
wherein the subject afflicted with scleroderma is not afflicted with cancer; and
wherein the growth, viability, or mobility of the cancer cell is reduced to a greater degree than would be observed when the cancer cell is assayed in the presence of a reference antibody obtained from a reference subject that is afflicted with scleroderma, wherein the reference subject is afflicted with cancer.