Patent ID: 11919935
Assignee: AKSTON BIOSCIENCES CORPORATION
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A recombinant cell comprising a nucleic acid encoding a fusion protein, said fusion protein comprising an insulin polypeptide and an Fc fragment, wherein the insulin polypeptide and the Fc fragment are connected by a linker, wherein the Fc fragment comprises the following sequence:, (SEQ ID NO: 32)

CPKCPAPEMLGGPSVFIFPPKPKDTLLIARTPEVTCVVVDLDPEDPEVQ

 

ISWFVDGKQMQTAKTQPREEQFKGTYRVVSVLPIGHQDWLKGKQFTCKV

 

NNKALPSPIERTISKARGQAHQPSVYVLPPSREELSKNTVSLTCLIKDF

 

FPPDIDVEWQSNGQQEPESKYRTTPPQLDEDGSYFLYSKLSVDKSRWQR

 

GDTFICAVMHEALHNHYTQESLSHSPG

and wherein the insulin polypeptide comprises the following sequence:, (SEQ ID NO: 16)

FVNQHLCGSDLVEALALVCGERGFFYTDPTGGGPRRGIVEQCCHSICSL

 

YQLENYCN.