Patent ID: 11932656
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 13:
14. A method of inhibiting cyclooxygenase-2 (COX-2) in a patient comprising administering to a patient in need thereof a compound selected from the group consisting of:
2-(4-Fluorobenzyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (4a);
2-(4-Methoxybenzyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (4b);
N-(5,6-Dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)-4-fluorobenzamide (5a);
N-(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)-2-(trifluoromethyl)benzamide (5b);
and a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof.