Patent ID: 11952411
Assignee: JANSSEN BIOTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 13:
14. The method of claim 12, wherein the engineered TL1A ligand comprises the amino acid sequence of any one of SEQ ID NO: 1-93, or wherein the engineered TL1A ligand comprises:
a. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:79;
b. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:72;
c. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:8;
d. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:65;
e. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:52;
f. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO: 14;
g. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:36;
h. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:90;
i. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:88;
j. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:91; or
k. an amino acid sequence that is at least 80%, at least 85%, at least 90%, at least 95%, at least 98%, or 100% identical over its entire length to the amino acid sequence of SEQ ID NO:89.