Patent ID: 11919951
Assignee: TRON—TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITäTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITäT MAINZ
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 0:
1. An antibody or antigen-binding fragment thereof that binds to claudin 6 (CLDN6), wherein said antibody or antigen-binding fragment thereof comprises:
(a) an antibody heavy chain variable region (VH) comprising:
a VHCDR1 having the amino acid sequence set forth in SEQ ID NO: 51;
a VHCDR2 having the amino acid sequence set forth in SEQ ID NO: 52; and
a VHCDR3 having the amino acid sequence set forth in SEQ ID NO: 53; and
an antibody light chain variable region (VL) comprising:
a VLCDR1 having the amino acid sequence set forth in SEQ ID NO: 54;
a VLCDR2 having the amino acid sequence set forth in SEQ ID NO: 55; and
a VLCDR3 having the amino acid sequence set forth in SEQ ID NO: 56; or

(b) an antibody heavy chain variable region (VH) comprising:
a VHCDR1 having the amino acid sequence set forth in SEQ ID NO: 57;
a VHCDR2 having the amino acid sequence set forth in SEQ ID NO: 58; and
a VHCDR3 having the amino acid sequence set forth in SEQ ID NO: 53; and
an antibody light chain variable region (VL) comprising:
a VLCDR1 having the amino acid sequence set forth in SEQ ID NO: 54;
a VLCDR2 having the amino acid sequence set forth in SEQ ID NO: 55; and
a VLCDR3 having the amino acid sequence set forth in SEQ ID NO: 56.