Patent ID: 11964967
Assignee: CYTOKINETICS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 8:
9. A compound selected from the group consisting of, 5-(5-ethyl-1,2,4-oxadiazol-3-yl)- 2,3-dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(R)-5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(S)-5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

5-(5-methyl-1,2,4-oxadiazol-3- yl)-2,3-dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(S)-5-(5-methyl-1,2,4-oxadiazol- 3-yl)-2,3-dihydrospiro[indene- 1,4′-oxazolidin]-2′-one; 

 

(R)-5-(5-methyl-1,2,4-oxadiazol- 3-yl)-2,3-dihydrospiro[indene- 1,4′-oxazolidin]-2′-one; 

 

5-(5-isopropyl-1,2,4-oxadiazol-3- yl)-2,3-dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(R)-5-(5-isopropyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(S)-5-(5-isopropyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(S)-5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(R)-5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(R)-5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

(S)-5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl)-2,3- dihydrospiro[indene-1,4′- oxazolidin]-2′-one; 

 

6-(5-ethyl-1,2,4-oxadiazol-3-yl)- 2H-spiro[benzofuran-3,4′- oxazolidin]-2′-one; 

 

(S)-6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2H-spiro[benzofuran-3,4′- oxazolidin]-2′-one; and 

 

(R)-6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2H-spiro[benzofuran-3,4′- oxazolidin]-2′-one;

or a pharmaceutically acceptable salt thereof.