Patent ID: 11970478
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 9:
10. A method of making the 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione compound of claim 1, the method comprising:
refluxing a mixture of 2-hydroxyquinoline-3-carbaldehyde, 5,5-dimethylcyclohexane-1,3-dione, and amino-ethanol in ethanol;
evaporating excess solvent under vacuum;
purifying a resulting solid by recrystallization from a mixture of ethanol/acetone; and
obtaining the 9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione compound.