Patent ID: 11911762
Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
Field: Measurement (Instruments)
Classification: CPC B  G | IPC B  G

Claim 16:
17. A system, comprising:
a microfluidic chip comprising:
a separation unit that isolates target particles from other particles included in a biological fluid sample in association with flow of the biological sample fluid through nanoscale deterministic lateral displacement arrays in fluid communication with an inlet bus formed around a perimeter of a first side of the nanoscale deterministic displacement arrays; and
a detection unit that receives the target particles as contained within buffer fluid supplied from an outlet bus in fluid communication with the nanoscale deterministic displacement arrays, wherein the detection unit comprises a sensing element configured to chemically react with one or more biomarkers associated with target particles in association with flow of the buffer fluid over the sensing element, and wherein the outlet bus surrounds the detection unit.