Patent ID: 11937587
Assignee: REGENERON PHARMACEUTICALS, INC.
Field: Measurement (Instruments)
Classification: CPC A  C  G  Y | IPC A  C  G

Claim 11:
12. The isolated mouse cell of claim 9, wherein the cell comprises a replacement of:
(i) a genomic nucleic acid sequence encoding an endogenous mouse CD3γ protein with the nucleic acid sequence encoding the functional chimeric human/mouse CD3γ protein,
(ii) a genomic nucleic acid sequence encoding an endogenous mouse CD3δ protein with the nucleic acid sequence encoding the functional chimeric human/mouse CD3δ protein, and
(iii) a genomic nucleic acid sequence encoding an endogenous mouse CD3γ protein with the nucleic acid sequence encoding the functional chimeric human/mouse CD3γ protein.