Patent ID: 11911502
Assignee: NODEN PHARMA DESIGNATED ACTIVITY COMPANY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method for induction of local anesthesia prior to performing a procedure on, through, or adjacent a mucous membrane of the nasal cavities of a patient comprising:
administering a pharmaceutical composition comprising:
about 3.5% to about 4.0% cocaine hydrochloride, in weight percentages based on total weight of the pharmaceutical composition,
about 0.7 mg/mL to about 1.3 mg/mL sodium benzoate, and
about 1.2 mg/mL to about 1.4 mg/mL citric acid,
provided that the pharmaceutical composition is an aqueous solution,
provided that the pharmaceutical composition has a pH of 2 to 4, and
provided that a concentration of benzoylecgonine in a volume of the pharmaceutical composition is at least 0.1 weight percent and does not exceed about 9.3 weight percent in the volume of the pharmaceutical composition after the volume of the pharmaceutical composition has been stored in a sealed container for six months at a temperature ranging from 38° C. to 42° C. and a relative humidity ranging from 70% to 80%.