Patent ID: 11970745
Assignee: nan
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A method for treating a human subject afflicted with a malignant disease, comprising administering to the subject an effective amount of a pharmaceutical compound that interacts with Programmed cell death protein 1 (PDCD1), wherein the pharmaceutical compound is an antibody that specifically binds to PDCD1, wherein DNA methylation in a promoter region of the CD274 gene in cells of the malignant disease and/or T lymphocytes interacting with the cells of the malignant disease is known, from a DNA methylation analysis of a sample of the subject's cells of the malignant disease and/or T lymphocytes interacting with the cells of the malignant disease, to be less than that of a reference value.