Patent ID: 11878098
Assignee: FRESENIUS MEDICAL CARE HOLDINGS, INC.
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 0:
1. A system, comprising:
a dialysis machine configured to provide hemodialysis treatment to a patient;
a monitoring device configured to obtain hematocrit measurements corresponding to blood of the patient during the hemodialysis treatment; and
a processing system configured to:
receive the hematocrit measurements;
determine an initial set of parameter values to be used with a two-compartment vascular refill model;
estimate values of one or more parameters for the patient based on the hematocrit measurements, the initial set of parameter values, and the two-compartment vascular refill model; and
output the estimated values for the patient;

wherein estimating the values of the one or more parameters for the patient based on the hematocrit measurements, the initial set of parameter values, and the two-compartment vascular refill model further comprises:
performing a parameter identification;
solving model equations using the initial set of parameter values to determine whether the two-compartment vascular refill model fits the hematocrit measurements; and
in response to determining that the two-compartment vascular refill model does not fit the hematocrit measurements, modifying the initial set of parameter values.