Patent ID: 11912701
Assignee: HEPAREGENIX GMBH
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The compound of claim 2, wherein R5 is selected from
(a) phenyl substituted with 1, 2 or 3 groups independently selected from
halogen,
alkyl,
alkoxy,
alkoxy wherein the alkyl group is substituted with 1, 2 or 3 hydroxy groups,
hydroxy,
—SO2NR10R10,
—CO2R10,
CN,
—SF5,)
alkyl-S(═O)(═NR10)— (S-alkyl sulfonimidoyl), and
1H- or 2H-tetrazolyl,

(b) naphthyl;
(c) a heteroaromatic 5- or 6-membered monocyclic group having 1 or 2 heteroatoms independently selected from O, N and S, wherein the heteroaromatic group is optionally substituted with 1, 2 or 3 groups independently selected from
alkyl,
haloalkyl,
cycloalkyl,
—NR10R10,
halogen,
hydroxy,
alkoxy, which is optionally substituted with —NR10R10,
—CN,
alkenyl,
alkynyl,
R10R10N—CO—,
alkyl-S(═O)(═NR10)—,
cycloalkyl-NR10,
alkyl-NR10—, wherein the alkyl group is substituted with hydroxy or alkoxy,
alkyl sulfanyl,
benzimidazolyl,
and
a non-aromatic heterocyclic 4-, 5- or 6-membered monocyclic group having 1 or 2 heteroatoms independently selected from O, and N, which heterocyclic group is optionally substituted with alkyl, hydroxyalkyl or hydroxy,

(d) cycloalkyl;
or a pharmaceutically acceptable salt, solvate or optical isomer thereof.