Patent ID: 11945823
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound having the formula I:, or a pharmaceutically acceptable salt or stereoisomer thereof,
wherein:
X is CH;
W is CH or N;
R1 is H;
R2 is H or OH;
R3 is Ar;
Ar is aryl or 5- or 6-membered heteroaryl, wherein the aryl or 5- or 6-membered heteroaryl is optionally substituted with one, two, or three substituents independently selected from the group consisting of CN, CH2NR5R6, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 cyanoalkyl, C(O)R5, C(O)NR5R6, C(O)OR5, NR5R6, NHC(O)R5, NHC(O)NHR5, NHC(O)OR5, NHS(O)2R5, NHS(O)2NHR5, OR5, OCH2C(O)R5, OCH2C(O)NR5R6, OCH2C(O)OR5, S(O)2NR5R6, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, and C3-C6 cyanocycloalkyl;
each R5 is independently H, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 cyanoalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, or C3-C6 cyanocycloalkyl; and
each R6 is independently H, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 cyanoalkyl, C3-C6 cycloalkyl, C3-C6 halocycloalkyl, or C3-C6 cyanocycloalkyl; or
any R5 and R6, taken together with the nitrogen atom to which they are attached, independently forms a nitrogen-containing heterocyclyl, wherein each nitrogen-containing heterocyclyl is optionally and independently substituted with one, two, or three substituents independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 trihaloalkyl, OH, and OC1-C6 alkyl.