Patent ID: 11970476
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 5:
6. A method of making the 6′-(4-chlorophenyl)-2′-alkoxy-3,4′-bipyridine-3′-carbonitrile of claim 1, the method comprising:
adding a mixture of 1-(4-chlorophenyl)ethan-1-one and 3-pyridine carboxaldehyde to a solution of a sodium alkoxide in an absolute alcohol and stirring to obtain a first reaction mixture;
adding malononitrile to the first reaction mixture to obtain a second reaction mixture;
irradiating the second reaction mixture followed by cooling to room temperature to obtain a crude product;
purifying the crude product by filtering and recrystallization using the absolute alcohol; and
obtaining the 6′-(4-chlorophenyl)-2′-alkoxy-3,4′-bipyridine-3′-carbonitrile compound.