Patent ID: 11944283
Assignee: TERUMO KABUSHIKI KAISHA
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 17:
18. A method comprising:
interposing a biodegradable sheet between anastomosis sites in a living body following a surgical procedure;
the biodegradable sheet that is interposed between the anastomosis sites possessing opposite surfaces and including a plurality of spaced-apart through-holes passing through the biodegradable sheet so that the plurality of spaced-apart through-holes open to the opposite surfaces of the biodegradable sheet, each of the plurality of the through-holes possessing a hole inner diameter D, a straight line distance between the outer periphery of each of the plurality of spaced-apart through-holes and an adjacent one of the plurality of spaced-apart through-holes being a pitch P of the through-hole;
the biodegradable sheet that is interposed between the anastomosis sites being configured so that a ratio (D/P) of the hole inner diameter D to the pitch P of each of the plurality of through-holes is 0.25 or more and less than 40; and
the biodegradable sheet that is interposed between the anastomosis sites causing a biological reaction that induces expression of a biological component that is accumulated from both of the opposite surfaces of the biodegradable sheet to the through-holes to promote adhesion at the anastomosis sites.