Patent ID: 11866726
Assignee: EDITAS MEDICINE, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The isolated nucleic acid of claim 1, wherein:
(i) Al has a sequence that is at least 40 nucleotides in length, and A2 has a sequence that is at least 40 nucleotides in length;
(ii) Al has a sequence that is identical to, or differs by no more than 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, or 30 nucleotides from a sequence of H1;
(iii) A2 has a sequence that is identical to, or differs by no more than 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, or 30 nucleotides from a sequence of H2;
(iv) N comprises an exon of a gene sequence, an intron of a gene sequence, a cDNA sequence, or a transcriptional regulatory element; a reverse complement of any of the foregoing or a portion of any of the foregoing; or
(v) N comprises a promoter sequence.