Patent ID: 11911355
Assignee: SEN-JAM PHARMACEUTICAL INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of inhibiting tolerance to an opioid by a human subject in need thereof, comprising:
administering an effective amount of a pharmaceutical composition to the subject during opioid therapy, wherein the pharmaceutical composition consists of:
a) a non-steroidal anti-inflammatory drug (NSAID) that is ibuprofen;
b) a co-agent that is ketotifen or salt thereof; and
c) a pharmaceutical carrier, a pharmaceutical excipient, a sweetening agent, a flavoring agent, a taste masking ingredient, a diluent, alum, a stabilizer, a buffer, a coloring agent, a breath neutralizer, a proton pump inhibitor, an emulsifying agent, a suspending agent and combinations thereof,
wherein tolerance to an opioid is inhibited in the human subject.