Patent ID: 11965183
Assignee: OXFORD NANOPORE TECHNOLOGIES PLC
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 18:
19. The method of claim 1, wherein the Dda helicase comprises substitutions at residues corresponding to: F98/K194/H64, F98/K194/T80, F98/K194/H82, F98/S83/K194, F98/S83/K194/F276, F98/P89/K194, F98/D121/K194, F98/V150/K194, F98/P152/K194, F98/F240/K194, F98/N242/K194, F98/K194/F276, F98/K194/S287, F98/N293/K194, F98/T394/K194, F98/H396/K194, F98/K397/K194, or F98/Y415/K194 in SEQ ID NO: 8.