Patent ID: 11942149
Assignee: MACROGENICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC G

Claim 7:
8. The method of claim 5, wherein:
the tumor antigen (TA) is 5T4; and
(I) (A) the second Light Chain Variable Domain CDRL1, CDRL2, and CDRL3 are the Light Chain CDRs of 5T4 MAB-1 VL (SEQ ID NO:135); and
(B) the second Heavy Chain Variable Domain CDRH1, CDRH2, and CDRH3 are the Heavy Chain CDRs of 5T4 MAB-1 VII (SEQ ID NO:134); or

(II) (A) the second Light Chain Variable Domain CDRL1, CDRL2, and CDRL3 are the Light Chain CDRs of 5T4 MAB-2 VL (SEQ ID NO:137); and
(B) the second Heavy Chain Variable Domain CDRH1, CDRH2, and CDRH3 are the Heavy Chain CDRs of 5T4 MAB-2 VII (SEQ ID NO:136).