Patent ID: 11945858
Assignee: NATIONAL RESEARCH COUNCIL OF CANADA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 4:
5. The antibody or antigen-binding fragment of claim 1, wherein said antibody comprises a variable heavy domain (VH) comprising the amino acid sequence:, (SEQ ID NO: 122)

EVKLVESGGGLVKPGGSLKLSCAASGFTFRSYAMSWVRQTPEKGLEWVAS

 

ISSGGSTYYPDSVKGRFTISRDNAGNILYLQMSSLRSEDTAMYYCARGYD

 

GYYERIWYYAMDYWGQGTSVTVSS 

 and a variable light domain (VL) comprising the amino acid sequence:, (SEQ ID NO: 124)

DIVMTQSQKFMSTSVGDRVTVSCKASQNVGTIVAWYQQKPGQSPKALIYS

 

ASYRFSGVPDRFTGSGSGTDFTLTISNVQSEDLAEYFCQQYNTYPLTFGS

 

GTKLEIK.