Patent ID: 11959898
Assignee: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Field: Measurement (Instruments)
Classification: CPC G  H | IPC G  H

Claim 8:
9. The system of claim 1, wherein the processor calculates the second XIC peak group that represents the at least one adduct, modified form, or peptide of the known compound from the L XICs using curve subtraction by
subtracting each XIC of the L XICs from each of the other L XICs, producing, (
  
   
    
     L
    
   
   
    
     2
    
   
  
  )
 

 subtraction curves, wherein each subtraction curve is calculated from a first XIC and a second XIC by, at each retention time, normalizing an intensity of the first XIC at the each retention time and two or more intensities of the first XIC at two or more adjacent retention times, normalizing an intensity of the second XIC at the each retention time and two or more intensities of the second XIC at the adjacent retention times, subtracting the normalized intensities of the second XIC from the corresponding normalized intensities of the first XIC, and calculating a statistical measure of the difference intensities,
identifying at least one region of one or more retention times where one or more subtraction curves of the, (
  
   
    
     L
    
   
   
    
     2
    
   
  
  )
 

 subtraction curves have values that are within a threshold value of zero, and
for the at least one region, obtaining two or more XICs used to calculate the one or more subtraction curves identifying the region and adding each peak of the two or more XICs that is in the region to the second XIC peak group.