Patent ID: 11969491
Assignee: TRUCAPSOL LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 15:
16. A method for preparing the controlled release particles of claim 1, said method comprising:
(a) preparing a first composition by mixing the at least one hydrophobic active material and the emulsifier;
(b) preparing a second composition by mixing the colloidal silica and optionally the film forming polymer to form a homogeneous solution;
(c) emulsifying the first composition in the second composition with agitation sufficient to achieve a desired particle size of dispersed particles in a dispersed phase of a resulting emulsion;
(d) adding the water insoluble divalent salt into the emulsion;
(e) adding the aqueous solution of shellac to the emulsion of step (d);
(f) assuring that a final pH of the emulsion of step (e) is from 7.2 to 8.5 to provide a spray-ready emulsion;
(h) spray drying the spray-ready emulsion to provide a powder comprising the controlled release particles; and optionally
(i) adding a silica flow aid to the powder to provide a modified powder.