Patent ID: 11918936
Assignee: WATERS TECHNOLOGIES CORPORATION
Field: Measurement (Instruments)
Classification: CPC B  C  G | IPC B  G

Claim 0:
1. A method of separating a sample comprising a low concentration of analyte:
providing a chromatographic system having a layer of alkylsilyl on at least a portion of a metallic flow path;
injecting the sample into the alkylsilyl coated metallic flow path of the chromatographic system;
flowing the sample through the alkylsilyl coated metallic flow path of the chromatographic system;
separating the sample;
detecting at least an amount of the low concentration of the analyte above a minimum expected value; and recovering greater than 80 percent of the analyte when the low concentration of the analyte extends from about 1 ng/mL to about 5 μg/mL.