Patent ID: 11896675
Assignee: ABTIS CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A modified antibody or its fragment comprising bio-orthogonal click chemistry functional group,
wherein the modified antibody comprises one or more modified heavy chain,
wherein each of the modified heavy chain comprises a modified lysine residue at 248 position of heavy chain amino acid sequence, wherein the 248 position is determined by an EU numbering system, and
wherein the modified lysine residue comprises a bio-orthogonal click chemistry functional group at terminal end, and
wherein the modified lysine residue does not comprise a terminal bio-reactive functional group selected from terminal hydroxy group, terminal carboxyl group, terminal thiol group, terminal amino group, and terminal aldehyde group.