Patent ID: 11918568
Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 10:
11. The pharmaceutical composition of claim 1, wherein the compound is selected from the group consisting of:
N-(2-phenyl-1,3-benzoxazol-5-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenyl-1,3-benzoxazol-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(2-methylphenyl)-1,3-benzoxazol-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[(1,3-oxazol-5-yl)methyl]-N-(2-phenyl-1,3-benzoxazol-6-yl)urea,
N-[2-(1-methyl-1H-pyrazol-4-yl)-1,3-benzoxazol-6-yl]-NL[(pyridin-4-yl)methyl]urea,
N-(5-fluoro-2-phenyl-1,3-benzoxazol-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenylimidazo[1,2-a]pyridin-7-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenyl-1H-indol-5-yl)-N′-[(pyridin-4-yl)methyl]urea,
methyl[2-phenyl-5-({[(pyridin-4-yl)methyl]carbamoyl}amino)-1H-indol-1-yl]acetate,
N-{2-[3-(methanesulfonyl)phenyl]-1-methyl-1H-indol-5-yl}-N′-[(pyridin-4-yl)methyl]urea,
N-{2-[3-(2-methoxyethoxy)phenyl]-1-methyl-1H-indol-5-yl}-N′-[(pyridin-4-yl)methyl]urea,
N-[1-(2-methoxyethyl)-2-phenyl-1H-indol-5-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[1-methyl-2-(pyridin-2-yl)-1H-indol-5-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-(1-methyl-2-phenyl-1H-indol-5-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-{1-[(1,4-dioxan-2-yl)methyl]-2-phenyl-1H-indol-5-yl}-N′-[(pyridin-4-yl)methyl]urea,
N,N-dimethyl-2-phenyl-5-({[(pyridin-4-yl)methyl]carbamoyl}amino)-1H-indole-1-carboxamide,
N-[1-(2-methylpropyl)-1H-indazol-5-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-[(1,3-oxazol-5-yl)methyl]-N′-(2-phenyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)urea,
N-(2-phenyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N′-[(1H-pyrazol-4-yl)methyl]urea,
N-[2-(2-butylphenyl) [1,2,4]triazolo[1,5-a]pyridin-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(1-phenyl-TH-pyrrol-2-yl)[1,2,4]triazolo[1,5-a]pyridin-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(1-methyl-1H-pyrazol-5-yl)[1,2,4]triazolo[1,5-a]pyridin-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[(pyridin-4-yl)methyl]-N′-{2-[2-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyridin-6-yl}urea,
N-(2-phenyl[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenylpyrazolo[1,5-a]pyridin-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(2-phenylpyrazolo[1,5-a]pyrimidin-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(3-methyl-2-phenylpyrazolo[1,5-a]pyridin-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(3-cyano-2-phenylpyrazolo[1,5-a]pyridin-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(3-methoxyphenyl)pyrazolo[1,5-a]pyridin-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N,N-dimethyl-2-phenyl-6-({[(pyridin-4-yl)methyl]carbamoyl}amino)pyrazolo[1,5-a]pyridine-3-carboxamide,
N-[3-(1-methyl-1H-pyrazol-5-yl)-2-phenylpyrazolo[1,5-a]pyridin-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
4-fluoro-N,N-dimethyl-2-phenyl-6-({[(pyridin-4-yl)methyl]carbamoyl}amino)pyrazolo[1,5-a]pyridine-3-carboxamide,
N-(2-phenyl-2H-indazol-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-[(1,3-oxazol-5-yl)methyl]-N′-(2-phenyl-2H-indazol-6-yl)urea,
N-[2-(3-methoxyphenyl)-2H-indazol-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-{2-[2-(2-methoxyethoxy)phenyl]-2H-indazol-6-yl}-N′-[(pyridin-4-yl)methyl]urea,
N-(3-methyl-2-phenyl-2H-indazol-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-{2-[3-(methanesulfonyl)phenyl]-2H-indazol-6-yl}-N′-[(pyridin-4-yl)methyl]urea,
N-(3-cyano-2-phenyl-2H-indazol-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N,N-diethyl-2-phenyl-6-({[(pyridin-4-yl)methyl]carbamoyl}amino)-2H-indazole-3-carboxamide,
N-[2-phenyl-3-(pyrrolidine-1-carbonyl)-2H-indazol-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[3-cyano-2-(2-methoxypyridin-4-yl)-2H-indazol-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(2-chlorophenyl)-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[4-(2-methoxyethyl)-2-phenyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-N′-[(pyridin-4-yl)methyl]urea,
2-(2-chlorophenyl)-N-ethyl-7-({[(pyridin-4-yl)methyl]carbamoyl}amino)-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide,
N-(2-phenyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(3-phenyl-5-propanoyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-8-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-(1-acetyl-2-phenyl-2,3-dihydro-1H-indol-5-yl)-N′-[(pyridin-4-yl)methyl]urea,
N,N-diethyl-6-({[(pyridin-4-yl)methyl]carbamoyl amino)-1,2-benzoxazole-3-carboxamide,
N-(2-phenyl-2,3-dihydro-1-benzofuran-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N-[2-(3-methoxyphenyl)-2,3-dihydro-1-benzofuran-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-[(2S,3S)-2-(3-methoxyphenyl)-3-methyl-2,3-dihydro-1-benzofuran-6-yl]-N′-[(pyridin-4-yl)methyl]urea,
N-(3-phenyl-2,3-dihydro-1-benzofuran-6-yl)-N′-[(pyridin-4-yl)methyl]urea,
N,N-diethyl-6-({[(pyridin-4-yl)methyl]carbamoyl}amino)-1-benzofuran-3-carboxamide,
N-benzyl-N-ethyl-6-({[(pyridin-4-yl)methyl]carbamoyl}amino)-1,2-benzoxazole-3-carboxamide, and
N-[3-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-1,2-benzoxazol-6-yl]-N′-[(pyridin-4-yl)methyl]urea, or a pharmaceutically acceptable salt thereof.