Patent ID: 11893733
Assignee: OUROTECH, INC.
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 0:
1. A method of analyzing an ex vivo solid cell culture over time, the method comprising:
determining a first response of a solid cell culture to a growth media including a treatment agent, the solid cell culture held in a cell culture chamber of a microfluidic chip by determining first location coordinates of at least a first single cell of the solid cell culture including a first x location coordinate, a first y location coordinate, and a first z location coordinate;
determining a second response of the solid cell culture to the growth media by determining second location coordinates of the at least first single cell of the solid cell culture including a second x location coordinate, a second y location coordinate, and a second z location coordinate; and
comparing the first response and the second response to determine a treatment efficacy,
wherein comparing the first response and the second response comprises comparing the first location coordinates to the second location coordinates to determine a difference between the first location coordinates and the second location coordinates, and wherein the difference between the first location coordinates and the second location coordinates is between at least one of the first x location coordinate and the second x location coordinate, the first y location coordinate and the second y location coordinate, or the first z location coordinate and the second z location coordinate, the difference representing a cell migration distance of the at least first single cell over time.