Patent ID: 11919881
Assignee: JANSSEN PHARMACEUTICA NV
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 3:
4. The compound of claim 1, wherein
R1 is selected from the group consisting of 1,2,3,4-tetrazol-1-yl, 4-chloro-1,2,3-triazol-1-yl and 4-(trifluoromethyl)-1,2,3-triazol-1-yl;
a is an integer from 1 to 2;
each R2 is independently selected from the group consisting of 5-chloro and 6-fluoro;
R4 is selected from the group consisting of 4-carboxyphenyl, 4-(methoxy-carbonyl-amino)-phenyl, 4-(trans-3-hydroxy-cyclopropyl-amino-carbonyl)-phenyl, pyridin-4-yl, 1-(methyl-d3)-pyrazol-5-yl, 1-methyl-1,2,3-triazol-5-yl and 1-(difluoro-methyl)-1,2,4-triazol-5-yl;
R5 is selected from the group consisting of ethyl, cyclopropyl-methyl-, 4-fluorophenyl-methyl-, 2-(difluoromethoxy)-ethyl-, S*-(2-(difluoromethoxy)-ethyl-), R*-(2-(difluoromethoxy)-ethyl-), S-(2-(difluoromethoxy)-ethyl-) and R-(2-(difluoromethoxy)-ethyl-);
R6 is hydrogen;
R7 is hydrogen;
or a pharmaceutically acceptable salt or solvate thereof.