Patent ID: 11897852
Assignee: THE UNIVERSITY OF TOLEDO
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A method of treating osteoarthritis by inducing chondrogenesis in a subject having osteoarthritis, the method comprising:
administering an effective amount of a pharmaceutical composition to the subject in need thereof sufficient to induce chondrogenesis;
the pharmaceutical composition comprising a peroxisome proliferator activated receptor (PPAR) compound in an amount sufficient to prompt stem cells in the subject to contribute toward improving cartilage health, and a pharmaceutically acceptable carrier, excipient, diluent or adjuvant;
wherein the PPAR compound has a chemical structure of Formula (12d):, , wherein:
X is S;
R1 is CF3;
R2 is F; and
R3 is H; and,
salts, isomers, solvates, hydrates, polymorphs and prodrugs thereof.