Patent ID: 11944719
Assignee: IVIVA MEDICAL, INC.
Field: Medical technology (Instruments)
Classification: CPC A  C | IPC A

Claim 13:
14. A method of making a composition, comprising:
a. generating a first sacrificial structure comprising one or more sacrificial materials on a support structure;
b. applying a thin film layer comprising functional basement membrane material to the first sacrificial structure, wherein the thin film layer has a thickness of about 10 μm or less and wherein the first sacrificial structure contacts a first side of the thin film layer;
c. applying a sacrificial material to a second side of the thin film layer to form a second sacrificial structure and embedding the second sacrificial structure in a material;
d. removing the sacrificial material to provide a first interior volume and a second interior volume having a boundary defined by the thin film layer, thereby making the composition,
wherein at least one of the first interior volume and second interior volume forms a vascular channel network with a volume of about 0.01 mL to about 10 L, wherein the functional basement membrane material comprises decellularized tissue that has been liquefied or homogenized.