Patent ID: 11958911
Assignee: SHANGHAI BENEMAE PHARMACEUTICAL
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An isolated anti-FXI or anti-FXIa antibody that specifically binds to human FXI or FXIa or immunologically active portion thereof wherein the antibody or portion thereof, comprises a combination of CDR selected from the group consisting of combinations a) to l):
combination a) CDRs of SEQ ID NOs: 11-16;
combination b) CDRs of SEQ ID NOs: 27-32;
combination c) CDRs of SEQ ID NOs: 43-48;
combination d) CDRs of SEQ ID NOs: 59-64;
combination e) CDRs of SEQ ID NOs: 75-80;
combination f) CDRs of SEQ ID NOs: 91-96;
combination g) CDRs of SEQ ID NOs: 107-112;
combination h) CDRs of SEQ ID NOs: 123-128;
combination i) CDRs of SEQ ID NOs: 139-144;
combination j) CDRs of SEQ ID NOs: 155-160;
combination k) CDRs of SEQ ID NOs: 171-176; and
combination l) CDRs of SEQ ID NOs: 187-192.