Patent ID: 11925692
Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G  B | IPC A  B

Claim 0:
1. A nanoparticle comprising a metal surface pre-functionalized with a self-assembled protective monolayer formed by a matrix of molecules M of formula (1): HS(CH2)n (OCH2CH2)m OH, in which:
n represents the number of CH2, where 3≤n≤11; and
m represents the number of ethylene glycol, where 1≤m≤12;
the molecules bearing a thiol function at one end thereof, the other end thereof being inert;
wherein a coverage rate of the monolayer is between 1.5% and 99%, and the nanoparticle is further functionalized with at least one L-PEG molecule of formula (7): SH—CH2CH2(CH2CH2O)qO—F, in which:
q represents the number of ethylene glycol, where 20≤q≤500; and
F represents a functional group selected from among CH3, OH, COOH or NH2, a coverage rate of the L-PEG molecule being at least 1%.