Patent ID: 11861830
Assignee: MERIT CRO, INC.
Field: Medical technology (Instruments)
Classification: CPC G  A | IPC A  G

Claim 0:
1. A method for determining the area and/or the volume of a retinal lesion, the method comprising:
1) obtaining Optical Coherence Tomography (OCT) data from a subject with a retinal lesion with a system comprising:
a) an OCT apparatus; and
b) software to calculate an area and/or volume of the region of interest V by implementing the following steps in response to a user of the system:
i) acquiring three-dimensional OCT data comprising at least a first segment and a second segment comprising a retinal lesion;
ii) acquiring two-dimensional image data comprising the tissue abnormality, wherein the tissue abnormality in the three-dimensional OCT data corresponds to the retinal lesion in the two-dimensional data;
iii) drawing a boundary around the retinal lesion in the two-dimensional image data, the boundary enclosing an area A, wherein the two-dimensional image data and three-dimensional OCT data are registered via a computer processor so that the retinal lesion is identified in the three-dimensional OCT data by the boundary drawn on the two-dimensional image and displayed on a computer screen;
iv) calculating a volume v within the boundary and between the first segment and the second segment;
v) calculating an average thickness t between the first segment and the second segment along the boundary; and
vi) calculating the volume of the region of interest V=v−(t×A); and
2) via operation of the system, determining the area and/or the volume of the retinal lesion by acquiring the OCT data, drawing the boundary, and calculating area and/or volume of the retinal lesion.