Patent ID: 11913026
Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 9:
10. The bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody of claim 9, wherein the anti-CD3 scFv is an scFv of anti-human CD3 murine monoclonal antibody OKT-3 having a binding specificity for CD3εγ and CD3εδ;or the anti-CD3 scFv is an scFv of anti-human CD3 murine monoclonal antibody UCHT1 having a binding specificity for CD3εγ and CD3εγ and has a (GGS)3 linker; or the anti-CD3 scFv is an scFv of anti-human CD3 murine monoclonal antibody SP34 having a binding specificity for CD3ε, CD3εγ and CD3εδ and has a (GGS)3 linker.