Patent ID: 11884711
Assignee: BEIJING QL BIOPHARMACEUTICAL CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 7:
8. The fusion polypeptide of claim 6, wherein the one or more mutations in GDF15 are selected from the group consisting of: R2S, R2A, R2E, N3S, N3E, N3A, N3T, N3P, N3G, N3V, N3H, N3Y, N3Q, H6D, P11E, H18E, H18Q, T19S, V20L, R21E, A30E, M43L, M43E, A47E, R53E, A54E, M57A, M57E, M57L, H66E, R67E, L68E, A75E, A81E, P85E, M86F, M86A, M86L, Q90E, T92E, L105E, deletion of N3, and deletion of N-terminal 1-3 residues, or any combination thereof, relative to SEQ ID NO: 9.