Patent ID: 11958877
Assignee: SINGULAR GENOMICS SYSTEMS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A kit comprising a labeled nucleotide, wherein the labeled nucleotide comprises:
(i) a cleavable moiety covalently bound to the 3′ oxygen of said labeled nucleotide, wherein the cleavable moiety has the formula -L1P-S—S—R6P(I); and
(ii) a nucleobase linked via a covalent linker to a first detectable moiety, wherein said covalent linker comprises, wherein,
R102 is unsubstituted C1-C4 alkyl;
L1P is a substituted methylene, wherein L1P is substituted with a substituted or unsubstituted alkyl, or a substituted or unsubstituted heteroalkyl; and
R6P is unsubstituted methyl or unsubstituted ethyl.