Patent ID: 11872212
Assignee: INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) KOLKATA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A process for the preparation of non-centrosymmetric organic crystals of substituted imidazole or dialkyl 4,4′-methylenebis (azanediyl)dibenzoate compounds, which process comprises;
a) dissolving the substituted imidazole or dialkyl 4,4′-methylenebis (azanediyl)dibenzoate compounds in a dust free organic solvent at a temperature of 30 to 60° C.;
b) slowly evaporating the solvent to obtain the respective crystals; and
c) fracturing the crystals by a three-point bending test into pieces wherein the pieces self-propel without external direction and recombine;
wherein the non-centrosymmetric organic crystals are selected from the group consisting of
a) 4,4′-methanediylbis-(2-ethyl-5-methyl-1H-imidazole);
b) diethyl 4,4′-(methylenebis(azanediyl))dibenzoate; and
c) dimethyl 4,4′-(methylenebis(azanediyl))dibenzoate.