Patent ID: 11925667
Assignee: nan
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A therapeutically enhanced probiotic organism comprising:
A bacterial chassis genetically reengineered to bind to the heparan sulfate proteoglycan (HSPG) on cancer cell surface and reengineered to secrete myrosinase for conversion of dietary-glucosinolate to sulforaphane wherein the bacterial chassis is Escherichia coli Nissle 1917(EcN) reengineered to bind to the heparan sulfate proteoglycan (HSPG) on cancer cell surface and reengineered to secrete myrosinase for conversion of dietary-glucosinolate to sulforaphane wherein said therapeutically enhanced probiotic organism contains genetic sequences having identity with Seq ID No. 4 and Seq ID No. 5.