Patent ID: 11931482
Assignee: BROWN UNIVERSITY
Field: Medical technology (Instruments)
Classification: CPC A  C | IPC A  C

Claim 12:
13. A method of making a device comprising an antibacterial coating, the method comprising the steps of:
dipping the device in a homogeneous polyurethane-auranofin-solvent solution and evaporating the solvent, to deposit the antibacterial coating consisting of a dried, homogenous solution of auranofin dissolved in polyurethane;
wherein a portion of the auranofin is hydrogen bonded with the polyurethane;
wherein the antibacterial coating is operative to provide a larger burst rate of release of auranofin into an aqueous environment in the first 24 hours of contact with said environment, followed by a slower and extended rate of release after the first 24 hours; and
wherein the antibacterial coating is operative to stretch up to about 500% elongation without breaking.