Patent ID: 11919936
Assignee: SHANGRAO CONCORD PHARMACEUTICAL CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The TEV protease variant according to claim 2, wherein the protease variant comprises the amino acid sequence shown in SEQ ID NO: 4, 5 or 6 or a homologue thereof, wherein the TEV protease variant comprising the amino acid sequence shown in SEQ ID NO: 4, 5 or 6 or the homologue thereof has a lower enzymatic cleavage activity than the S219V variant having the amino acid sequence shown in SEQ ID NO: 10 during expression in a host, and the TEV protease variant comprising the amino acid sequence shown in SEQ ID NO: 4, 5 or 6 or the homologue thereof retains extracellular enzymatic cleavage activity of S219V variant under a moderate to high degree of denaturation conditions.