Patent ID: 11904053
Assignee: MEDIMMUNE LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A dry powder formulation comprising a plurality of microparticles, the microparticles comprising:
a. about 8% to about 11% leucine by weight;
b. about 2% to about 4% trileucine by weight; and
c. an antigen binding fragment of an anti-thymic stromal lymphopoietin (TSLP) antibody comprising:
a heavy chain variable domain comprising:
i. a heavy chain CDR1 sequence consisting of the amino acid sequence set forth in SEQ ID NO:1;
ii. a heavy chain CDR2 sequence consisting of the amino acid sequence set forth in SEQ ID NO:2; and
iii. a heavy chain CDR3 sequence consisting of the amino acid sequence set forth in SEQ ID NO:3, and

a light chain variable domain comprising:
i. a light chain CDR1 sequence consisting of the amino acid sequence set forth in SEQ ID NO:5;
ii. a light chain CDR2 sequence consisting of the amino acid sequence set forth in SEQ ID NO:6, and
iii. a light chain CDR3 sequence consisting of the amino acid sequence set forth in SEQ ID NO:7.