Patent ID: 11903951
Assignee: M ET P PHARMA AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 16:
17. A nasal pharmaceutical composition in the form of a gel adapted for nasal administration, comprising:
(a) a loaded porous excipient comprising mesoporous silica particles wherein active agent in an amorphous state is loaded onto surfaces of the mesoporous silica particles located inside pores of the mesoporous silica particles, wherein the composition comprises from about 0.5% to about 50% w/w of the mesoporous silica based on the weight of the composition;
(b) a lipophilic or partly lipophilic vehicle comprising an oil or mixture of oils in an amount from about 50% to about 90% w/w of the composition and a viscosity-regulating agent,
wherein the loaded porous excipient is dispersed in the vehicle, and
wherein the composition comprises a therapeutically effective amount of the active agent of from 10% w/w to 50% w/w based on the weight of the composition, in a volume suitable for nasal application, and wherein the composition has a viscosity of from about 2000 to about 6000 mPa·sec.