Patent ID: 11879159
Assignee: BEIJING ORIGINPOLY BIO-TEC CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The composition for early detection of high-grade cervical lesions and cervical cancer according to claim 1, characterized in that: the composition further includes FAM19A4 gene methylation blocking primers, JAM3 gene methylation blocking primers and PAX1 gene methylation blocking primers, wherein:
the sequence of the FAM19A4 gene methylation blocking primer 1 is SEQ ID NO. 13 with a -C3 spacer at its 3′ end;
the sequence of the FAM19A4 gene methylation blocking primer 2 is SEQ ID NO. 14 with a -C3 spacer at its 3′ end;
the sequence of the JAM3 gene methylation blocking primer 1 is SEQ ID NO. 15 with a -C3spacer at its 3′ end;
the sequence of the JAM3 gene methylation blocking primer 2 is SEQ ID NO. 16 with a -C3spacer at its 3′ end;
the sequence of the PAX1 gene methylation blocking primer 1 is SEQ ID NO. 17 with a -C3spacer at its 3′ end; and
the sequence of the PAX1 gene methylation blocking primer 2 is SEQ ID NO. 18 with a -C3spacer at its 3′ end.