Patent ID: 11896931
Assignee: THE AUTOMATION PARTNERSHIP (CAMBRIDGE) LIMITED
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 4:
5. The computerized control system according to claim 1, wherein the plurality of process parameters comprises one or more of:
the plurality of sensor signals;
the transmembrane pressure of the crossflow filtration system;
the pressure difference between the feed pressure signal, indicating a pressure in a feed stream of the crossflow filtration system, and the retentate pressure signal, indicating a pressure in a retentate stream of the crossflow filtration system; or
a permeate flow rate, indicating a flow rate through a filter membrane of the crossflow filtration system,
wherein preferably the permeate flow rate F is determined according to, F
  =
  
   L
   -
   
    
     dM
     dt
    
    ⋆
    
     1
     ρ
    
   
  
 

with a change of a measured retentate mass M over time t, a retentate density p, and a flow rate L of a diafiltration buffer added to a retentate in the crossflow filtration system.