Patent ID: 11858907
Assignee: RHIZEN PHARMACEUTICALS AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 0:
1. A compound of formula, or a tautomer thereof, N-oxide thereof, pharmaceutically acceptable ester thereof, prodrug thereof, or pharmaceutically acceptable salt thereof, wherein
each occurrence of R is independently selected from hydrogen, halogen, —ORa, CN, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, substituted or unsubstituted C3-8 cycloalkyl, and substituted or unsubstituted heterocyclic group;
R1 and R2 may be the same or different and are independently selected from hydrogen, halogen, and substituted or unsubstituted C1-6 alkyl, or both R1 and R2 directly bound to the carbon atom to which they are attached, may be joined to form a substituted or unsubstituted saturated or unsaturated 3-10 member ring, which may optionally include one or more heteroatoms which may be the same or different and are selected from O, NRa and S;
Cy1 is a monocyclic group selected from substituted or unsubstituted cycloalkyl, substituted heterocyclic group, substituted or unsubstituted aryl and unsubstituted heteroaryl;
Cy2 is selected from a substituted heterocyclic group, substituted aryl and substituted or unsubstituted heteroaryl;
L1 is absent or selected from —(CRaRb)q—, or —C(═Y)—;
each occurrence of Ra and Rb may be the same or different and are independently selected from hydrogen, halogen, hydroxy, cyano, substituted or unsubstituted (C1-6)alkyl, —NRcRd (wherein Rc and Rd are independently hydrogen, halogen, hydroxy, cyano, substituted or unsubstituted (C1-6)alkyl, and (C1-6)alkoxy) and —ORc (wherein Rc is substituted or unsubstituted (C1-6)alkyl) or Ra and Rb are directly bound to a common atom, they may be joined to form an oxo group (═O) or form a substituted or unsubstituted saturated or unsaturated 3-10 member ring, which may optionally include one or more heteroatoms which may be the same or different and are selected from O, NRd (wherein Rd is hydrogen or substituted or unsubstituted (C1-6)alkyl) or S;
Y is selected from O, S, and NRa;
n is an integer from 1 to 4; and
q is 0, 1 or 2.