Patent ID: 11884720
Assignee: AMGEN RESEARCH (MUNICH) GMBH
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 5:
6. The bispecific antibody construct according to claim 1 comprising in an N- to C-terminal order:
the first binding domain comprising the amino acid sequence selected from the group consisting of: SEQ ID NO: 169, SEQ ID NO: 179, SEQ ID NO: 189, SEQ ID NO: 199, and SEQ ID NO: 209;
a peptide linker comprising the amino acid sequence selected from the group consisting of: SEQ ID NOs: 2, 8 and 9;
the second binding domain comprising the amino acid sequence selected from the group consisting of: SEQ ID NO: 19, SEQ ID NO: 28, SEQ ID NO: 37, SEQ ID NO: 46, SEQ ID NO: 55, SEQ ID NO: 64, SEQ ID NO: 73, SEQ ID NO: 82, SEQ ID NO: 91, SEQ ID NO: 100, SEQ ID NO: 103, SEQ ID NO: 318, SEQ ID NO: 319, SEQ ID NO: 320, SEQ ID NO: 321, SEQ ID NO: 322, SEQ ID NO: 323, SEQ ID NO: 324, SEQ ID NO: 325, SEQ ID NO: 326, and SEQ ID NO: 327;
a peptide linker comprising the amino acid sequence selected from the group consisting of: SEQ ID NOs: 1, 2, 4, 5, 6, 8 and 9; and
a third domain comprising the amino acid sequence selected from the group consisting of: SEQ ID NOs: 260-267.