Patent ID: 11865228
Assignee: NATIONAL UNIVERSITY OF KAOHSIUNG
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A method for manufacturing a bone void filler by a natural calcium-containing waste, comprising steps of:
(a) uniformly mixing 5-20 wt % of a powder of calcium-containing waste, 5-20 wt % of acetic acid and a remaining weight percentage of water to obtain a mixing solution, wherein the powder of calcium-containing waste comprises an eggshell powder, a shell powder of Crustacea animals, a shell powder of Bivalvia animals or a shell powder of Gastropoda animals;
(b) adding 5-20 vol % of a diammonium hydrogen phosphate solution into the mixing solution to obtain a suspension;
(c) controlling a pH value of the suspension between 7.5 and 14 to obtain an alkaline solution;
(d) leaving the alkaline solution at room temperature for precipitation for 0.1-72 hours, preforming a centrifugal process or a suction filtration process on the alkaline solution to obtain a precipitate, drying and grinding the precipitate to obtain a hydroxyapatite; and
(e) uniformly mixing 30-60 wt % of a pore former, 30-60 wt % of the hydroxyapatite and a remaining weight percentage of a binder to form a mixture, compression molding the mixture in a mold and then sintering the compression-molded mixture at a sintering temperature to obtain the bone void filler.