Patent ID: 11918013
Assignee: RESORCIX LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 5:
6. The method of claim 4, wherein at least one of the following is true:
(1) the ratio of ethanol to water in the mixture is at least by weight;
(2) the ratio of ethanol to water in the mixture is not more than 4:1 by weight;
(3) the mixture of ethanol and water contains (a) NaOH in a concentration of 0.01 to 0.125 molar, or (b) HCl in a concentration of 0.01 to 0.25 molar;
(4) the ratio of the mixture of ethanol and water to copaiba resin is at least 3:1 by weight;
(5) the upper fraction contains crolechinic acid, hardwickiic acid, kolavenic acid, copalic acid, and, optionally, 7-alpha-acetoxyhardwickiic acid, and the ratio of said 7-alpha-acetoxyhardwickiic acid (when present), crolechinic acid, hardwickiic acid, kolavenic acid and copalic acid, taken together, to said BCP in said upper fraction is at least 1.1:1 by weight.