Patent ID: 11898142
Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Field: Measurement (Instruments)
Classification: CPC C  B  G  Y | IPC B  C  G

Claim 6:
7. The system of claim 1, wherein the CRISPR effector protein having collateral cleavage activity is CRISPR RNA-targeting effector protein; wherein the CRISPR RNA-targeting effector protein optionally comprises one or more HEPN domains; wherein the one or more HEPN domains optionally comprise a RxxxxH motif sequence; wherein the RxxxxH motif sequence optionally comprises a R{N/H/K]X1X2X3H sequence; and wherein X1 is R, S, D, E, Q, N, G, or Y, and X2 is independently I, S, T, V, or L, and X3 is independently L, F, N, Y, V, I, S, D, E, or A.