Patent ID: 11859008
Assignee: GANYMED PHARMACEUTICALS GMBH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A method of producing a transformed cell, the method comprising the steps of:
(a) transforming a human host cell with one or more expression vectors, wherein the one or more expression vectors comprise:
(i) a nucleic acid sequence encoding a first polypeptide comprising the antibody heavy chain CDR1, CDR2, and CDR3 regions having the amino acid sequences of positions 26-33, positions 51-58, and positions 97-106 of SEQ ID NO: 36, respectively; and
(ii) a nucleic acid sequence encoding a second polypeptide comprising the antibody light chain CDR1, CDR2, and CDR3 regions having the amino acid sequences of positions 27-31, positions 49-51, and positions 88-97 of SEQ ID NO: 35, respectively;

(b) culturing the transformed human host cell under conditions in which the transformed human host cell expresses the first and second polypeptides encoded by the one or more expression vectors; and
(c) harvesting the transformed human host cell expressing the first and second polypeptides.