Patent ID: 11913964
Assignee: ADEPTRIX CORP.
Field: Measurement (Instruments)
Classification: CPC G | IPC A  C  G

Claim 14:
15. A method for analyzing a biological sample, the method comprising the steps of:
obtaining a first plurality of endogenous amyloid beta (Aβ) peptides by subjecting a biological sample containing human cerebrospinal fluid (CSF) to immunoprecipitation (IP) using a first antibody,
then obtaining a second plurality of endogenous Aβ peptides by subjecting the biological sample to IP using a second antibody, and
analyzing at least one of the first and the second pluralities using mass spectrometry,
wherein the analyzing step comprises obtaining a mass spectrometry signal from at least one endogenous CSF Aβ peptide selected from the group of Aβ1-6, Aβ1-7, Aβ1-8, Aβ1-9, Aβ1-10, Aβ1-11, Aβ1-21, Aβ1-22, Aβ1-23, Aβ1-24, Aβ1-25, Aβ1-26, Aβ1-31, and Aβ1-32.