Patent ID: 11898129
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Field: Biotechnology (Chemistry)
Classification: CPC C  B | IPC B  C

Claim 0:
1. A method of loading a flowable material into a compartment of an on-chip microfluidic platform, comprising
passing a flowable material from an inlet region of a microfluidic channel to a downstream outlet region of the microfluidic channel and into a compartment fluidly connected to an outlet region, and
diverting, a part of the flowable material from the microfluidic channel through a bypass channel into a reservoir, the bypass channel being fluidity connected via a pressure safety capillary burst valve to the microfluidic channel upstream of the compartment, wherein the flowable material is diverted when the hydraulic pressure inside the microfluidic channel is higher than the pressure safety capillary burst valve burst pressure.