Patent ID: 11925630
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 2:
3. A method of making a 6′-(2-bromophenyl)-2′-methoxy-3,4′-bipyridine-3′-carbonitrile compound having the formula I:, , the method comprising:
adding a mixture of o-bromoacetophenone and 3-pyridinecarboxaldehyde to a solution of a sodium methoxide in an absolute ethanol with stirring to obtain a first reaction mixture;
adding malononitrile to the first reaction mixture to obtain a second reaction mixture;
irradiating the second reaction mixture followed by cooling to room temperature to obtain a solid precipitate;
purifying the solid precipitate by filtering and recrystallization using ethanol; and
obtaining the 6′-(2-bromophenyl)-2′-methoxy-3,4′-bipyridine-3′-carbonitrile compound.