Patent ID: 11857778
Assignee: CALA HEALTH, INC.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 11:
12. A wearable device for treating symptoms of an inflammatory gastrointestinal disease in a patient with transcutaneous stimulation of one or more peripheral nerves comprising:
a controller;
a first peripheral nerve effector, comprising at least one stimulation electrode configured to be positioned on the skin to stimulate a first peripheral nerve of the patient;
a first sensor or data input source, comprising at least one sensing electrode configured to be positioned on the skin to measure activity of the first peripheral nerve;
wherein the controller comprises a processor and a memory for receiving feedback information from one or more sensors that, when executed by the processor, cause the device to:
calculate one or more features of nerve conduction velocity of the first peripheral nerve based at least in part on the feedback information of the first sensor;
adjust one or more parameters of a first electrical stimulus based at least in part one or more features of nerve conduction velocity to selectively activate or maximize activation of a preselected fiber type in the first peripheral nerve; and
deliver a first electrical stimulus to a first peripheral nerve through the first peripheral nerve effector to modify at least one brain or spinal cord autonomic feedback loop relating to release of neurotransmitters from an autonomic nervous system that modulate synthesis of inflammatory biomarkers and reduce inflammation relating to the inflammatory gastrointestinal disease.