Patent ID: 11926642
Assignee: PFIZER INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 3:
4. The compound of claim 3 which is crystalline (3S)-3-({N-[(4-methoxy-1H-indol-2-yl)carbonyl]-L-leucyl}amino)-2-oxo-4-[(3S)-2-oxopyrrolidin-3-yl]butyl dihydrogen phosphate, methyl ethyl ketone solvate having one or more characteristics selected from the group consisting of a powder X-ray diffraction pattern, a 13C NMR spectrum and a Raman spectrum;
wherein the powder X-ray diffraction pattern characteristic is selected from
a) a powder X-ray diffraction pattern comprising peaks at 7.7±0.2, 8.1±0.2 and 23.1±0.2 degrees 2-Theta;
b) a powder X-ray diffraction pattern comprising peaks at 7.7±0.2, 8.1±0.2, 23.1±0.2 and 17.0±0.2 degrees 2-Theta; and
c) a powder X-ray diffraction pattern comprising peaks at 7.7±0.2, 8.1±0.2, 23.1±0.2, 17.0±0.2 and 25.8±0.2 degrees 2-Theta;
wherein the 13C solid state NMR spectrum characteristic is selected from
a) a 13C solid state NMR spectrum comprising peaks at 7.2, 206.4 and 215.8 ppm; each ±0.2 ppm;
b) a 13C solid state NMR spectrum comprising peaks at 7.2, 206.4, 215.8 and 42.2 ppm; each ±0.2 ppm; and
c) a 13C solid state NMR spectrum comprising peaks at 7.2, 206.4, 215.8, 42.2 and 101.2 ppm; each ±0.2 ppm; and
wherein the Raman spectrum characteristic is selected from

a) a Raman spectrum comprising peaks at 1511, 1644 and 3081 cm−1, each ±2 cm−1,
b) a Raman spectrum comprising peaks at 1511, 1644, 3081 and 1265 cm−1; each ±2 cm−1; and
c) a Raman spectrum comprising peaks at 1511, 1644, 3081,1265 and 446 cm−1; each ±2 cm−1.