Patent ID: 11911452
Assignee: SANOFI PASTEUR INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 7:
8. The method of claim 1, wherein in step (c), 0.02-0.19 μg of periodate is reacted with 1 μg of the Streptococcus pneumoniae serotype 9N capsular polysaccharide, and wherein the immunogenic serotype 9N conjugate formed in step (d) has a molecular weight of 500-4,000 kDa, a molecular weight distribution of 15-60% with a Kd of 0.3 or below as measured in a CL-4B column, and a CRM197/polysaccharide ratio of 0.5-2.5.