Patent ID: 11970744
Assignee: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Field: Measurement (Instruments)
Classification: CPC C  G  Y | IPC C  G

Claim 0:
1. A method for generating a transcriptome profile in a sample from an individual suffering from or at risk of colorectal cancer, the method comprising:
(i) in the sample, measuring a level of RNA corresponding to a ABHD2 gene and a level of RNA corresponding to
(a) a COL10A1 gene,
(b) a MMP11 gene, or
(c) both (a) and (b); and

(ii) determining a difference between the measured level of RNA corresponding to the ABHD2 gene and an ABHD2 threshold level, and
(a) determining a difference between the measured level of RNA corresponding to the COL10A gene and an COL10A threshold level,
(b) determining a difference between the measured level of RNA corresponding to the MMP11 gene and an MMP11 threshold level, or
(c) both (a) and (b); and
(iii) generating a transcriptome profile based on the differences determined in (ii).