Patent ID: 11872371
Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 2:
3. The method of claim 1, wherein the calibration phase comprises the following steps in sequential order:
i) signal conditioning and decomposition of a raw vagus nerve recording to obtain a conditioned and decomposed signal,
ii) feature detection of the signal obtained in i) to obtain a signal with feature detection,
iii) dimensionality reduction and unsupervised classification of the signal obtained in ii) to obtain a signal with dimensionality reduction and unsupervised classification,
iv) neural response extraction of the signal obtained in iii) to obtain a signal with event rates,
v) low-pass filtering the signal with event rates to obtain a smoothed event rate signal, and
vi) lagged linear regression of the smoothed event rate signals to obtain a mapping between the neural event rate signals and the blood glucose levels.