Patent ID: 11957749
Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 3:
4. The immunogenic combination according to claim 3, wherein the ChAd vector of component a) of the combination further comprises a polynucleotide encoding the human invariant chain (hli) fused to the HBc, the recombinant HBc of component c) of the combination is C-terminal truncated, the adjuvant of component c) of the combination contains MPL and QS-21, and the ratio of recombinant HBc to recombinant HBs of component c) of the combination is about 1.5:1, 2:1, 2.5:1, 3:1, 3.5:1, 4:1, 4.5:1, 5:1, 5.5:1, or 6:1.