Patent ID: 11905326
Assignee: TENEOBIO, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A multi-specific binding compound comprising a first binding unit having binding affinity to CD22 and a second binding unit having binding affinity to CD3, wherein the first binding unit having binding affinity to CD22 comprises a heavy chain variable region comprising:
(a) a CDR1 sequence of SEQ ID NO: 1, a CDR2 sequence of SEQ ID NO: 11, and a CDR3 sequence of SEQ ID NO: 18;
(b) a CDR1 sequence of SEQ ID NO: 1, a CDR2 sequence of SEQ ID NO: 12, and a CDR3 sequence of SEQ ID NO: 19; or
(c) a CDR1 sequence of SEQ ID NO: 1, a CDR2 sequence of SEQ ID NO: 12, and a CDR3 sequence of SEQ ID NO: 20; and
wherein the second binding unit comprises:
(a) a heavy chain variable region comprising a CDR1 sequence of SEQ ID NO: 85, a CDR2 sequence of SEQ ID NO: 86, and a CDR3 sequence of SEQ ID NO: 87; and
(b) a light chain variable region comprising a CDR1 sequence of SEQ ID NO: 88, a CDR2 sequence of SEQ ID NO: 89, and a CDR3 sequence of SEQ ID NO: 90.