Patent ID: 11872371
Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 8:
9. The method of claim 7, wherein the calibration phase comprises the following steps in sequential order:
i) signal conditioning and decomposition of a raw vagus nerve recording to obtain a conditioned and decomposed signal,
ii) feature detection of the signal obtained in i) to obtain a signal with feature detection,
iii) dimensionality reduction and unsupervised classification of the signal obtained in ii) to obtain a signal with dimensionality reduction and unsupervised classification,
iv) neural response extraction of the signal obtained in iii) to obtain a signal with event rates, and
v) passing the signal with event rates through a decoder to obtain a mapping between nerve signals and blood cytokine levels.