Patent ID: 11873343
Assignee: AMGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 40:
41. The aqueous pharmaceutical formulation of claim 28, comprising (i) about 100 mg/mL to about 140 mg/mL of denosumab and (ii) about 5 mM to about 100 mM phenylalanine or tryptophan, (iii) about 2.0 (w/w) % to about 5.0 (w/w) % tonicity modifier, and (iv) at least about 0.004 (w/v) % surfactant and less than 0.15 (w/v) % surfactant, wherein the aqueous pharmaceutical formulation has a pH in a range of about 5.0 to about 5.2.