Patent ID: 11866432
Assignee: INCYTE CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC A  C

Claim 19:
20. The method of claim 1, wherein:
R1 is H;
R2 is selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, C3-7 cycloalkyl, phenyl, 4-7 membered heterocycloalkyl, 5-6 membered heteroaryl, C3-7 cycloalkyl-C1-4 alkyl, phenyl-C1-4 alkyl, 4-7 membered heterocycloalkyl-C1-4 alkyl, and 5-6 membered heteroaryl-C1-4 alkyl, each of which is optionally substituted with 1, 2, 3, or 4 independently selected R2A substituents;
R3 is selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, C3-7 cycloalkyl, phenyl, 4-7 membered heterocycloalkyl, 5-6 membered heteroaryl, C3-7 cycloalkyl-C1-4 alkyl, phenyl-C1-4 alkyl, 4-7 membered heterocycloalkyl-C1-4 alkyl, and 5-6 membered heteroaryl-C1-4 alkyl, each of which is optionally substituted with 1, 2, 3, or 4 independently selected R3A substituents;
R4 and R5 are each independently selected from C1-6 alkyl and C1-6 haloalkyl;
or, alternatively, R4 and R5, together with the carbon atom to which they are attached form a 3, 4, 5, or 6 membered cycloalkyl ring;
R6 and R7 are each independently selected from H and C1-6 alkyl;
each R2A is independently selected from halo, CN, NO2, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, ORa1, SRa1, C(═O)Rb1, C(═O)NRc1Rd1, C(═O)ORa1, OC(═O)Rb1, OC(═O)NRc1Rd1, NRc1Rd1, NRc1C(═O)Rb1, NRc1C(═O)ORb1, NRc1C(═O)NRc1Rd1, NHORa1, NRc1S(═O)2Rb1, NRc1S(═O)2NRc1Rd1, S(═O)2Rb1, and S(═O)2NRc1Rd1;
each Ra1, Rc1, and Rd1 is independently selected from H, C1-6 alkyl, and C1-6 haloalkyl;
each Rb1 is independently selected from C1-6 alkyl and C1-6 haloalkyl;
each R3A is independently selected from halo, CN, NO2, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 haloalkyl, ORa2, SRa2, C(═O)Rb2, C(═O)NRc2Rd2, C(═O)ORa2, OC(═O)Rb2, OC(═O)NRc2Rd2, NRc2Rd2, NRc2C(═O)Rb2, NRc2C(═O)ORb2, NRc2C(═O)NRc2Rd2, NHORa2, NRc2S(═O)2Rb2, NRc2S(═O)2NRc2Rd2, S(═O)2Rb2, and S(═O)2NRc2Rd2;
each Ra2, Rc2, and Rd2 is independently selected from H, C1-6 alkyl, and C1-6 haloalkyl; and
each Rb2 is independently selected from C1-6 alkyl and C1-6 haloalkyl.