Patent ID: 11860171
Assignee: HANGZHOU CALIBRA DIAGNOSTICS CO., LTD.
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A screening, confirmed and typing diagnosis system for primary aldosteronism, wherein the system consists of a marker test module, a data input/output interface and a data analysis module; wherein the markers test module is configured to obtain test values of markers by a method of detecting the markers in blood, the data input/output interface is configured to input the test values of five markers, the data analysis module is configured to analyze the test values of the markers, the markers are aldosterone, angiotensin I, angiotensin II, cortisol and 18-hydrocorticosterone; and, wherein after analysis by the data analysis module, the data input/output interface is configured to output a screening, confirmed and typing diagnosis result of primary aldosteronism,
wherein the method of detecting the markers in the blood comprises the following steps:
(1) treating a blood sample with a magnetic bead bonded with a balanced hydrophilic-lipophilic polymer on a surface of the magnetic bead to absorb the markers in the blood sample; and
(2) using an eluent solution to eluent the markers from the magnetic bead, and using a liquid chromatography tandem-mass spectrometry to test contents of the markers in the blood sample, wherein the markers are aldosterone, angiotensin I, angiotensin II, cortisol and 18-hydrocorticosterone.