Patent ID: 11884724
Assignee: MERCK PATENT GMBH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An isolated anti-PD-L1 antibody or antigen binding fragment thereof comprising:
(a) a heavy chain variable region; and
(b) a light chain variable region
comprising HVR-L1, HVR-L2 and HVR-L3 sequences,, wherein:
(i) the HVR-L1 sequence is TGTX7X8DVGX9YNYVS (SEQ ID NO: 8); and
(ii) the HVR-L3 sequence is SSX13TX14X15X16X17RV (SEQ ID NO: 10); and
wherein X7 is N or S; X8 is T, R or S; X9 is A or G; X13 is F or Y; X14 is N or S; X15 is R, T or S; X16 is G or S; and X17 is I or T.