Patent ID: 11932855
Assignee: DUKE UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A composition comprising one or more antisense oligonucleotides, wherein the one or more antisense oligonucleotides are selected from SEQ ID NOs:1-11 and one or a combination of chemical modifications comprising phosphate backbone modifications, phosphorothioate (PS) backbone modification, ribose sugar group modifications, 2′-O-methyl (2OMe) modification, 2′-O-methoxy-ethyl (MOE) modification, locked nucleic acid (LNA) modification, tricyclo-DNA (tc-DNA) modification, 2′-fluoro modification, S-constrained-ethyl (cEt) modification, peptide nucleic acid (PNA) modification, or phosphorodiamidate morpholino oligomer (PMO) modification.