Patent ID: 11865090
Assignee: HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of treating hepatocellular carcinoma in a subject in need thereof, the method comprising administering to the subject a composition comprising a RORα agonist, selected from the group consisting of SR1078 and Lauric acid (LA), capable of increasing production or expression of one or more endogenous tumor suppressive miRNAs in one or more miRNA producing cells, wherein the one or more tumor suppressive endogenous miRNAs comprise miR-34a, such that the one or more endogenous tumor suppressive miRNAs affect one or more target hepatocellular carcinoma cells, thereby treating hepatocellular carcinoma in said subject.