Patent ID: 11925691
Assignee: HANMI PHARM. CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A compound selected from a compound of the following Formula 1a, a stereoisomer thereof, a solvate thereof, and a pharmaceutically acceptable salt thereof:, in Formula 1a,
n is an integer of 20 to 1000;
j is an integer of 0 to 6;
R1 is an aliphatic hydrocarbon group comprising an aldehyde group;
R2 is —(R3)k-(Z)l—(R4)m-(CZ)p—Y,
wherein R3 and R4 are each independently C1-C6 alkylene, C6-C20 arylene, or C5-C20 heteroarylene having 1 to 3 heteroatoms selected from N, O, and S,
Z is O or S,
Y is selected from the group consisting of bicyclo[6.1.0]nonyne (BCN), dibenzocyclooctyne (DBCO), difluorinated cyclooctyne (DIFO), DIFO2, DIFO3, dibenzoannulated cyclooctyne (DIBO), biarylazacyclooctynone (BARAC), cyclooctyne (OCT), aryl-less cyclooctyne (ALO), monofluorinated cyclooctyne (MOFO), dimethoxyazacyclooctyne (DIMAC), 2,3,6,7-tetramethoxy-DIBO (TMDIBO), carboxymethylmonobenzocyclooctyne (COMBO), pyrrolocyclooctyne (PYRROC), dibenzo-aza-cyclooctyne (DIBAC), 3,3,6,6-tetramethylthiacycloheptyne (TMTH), Sondheimer diyne, and sulfonylated DIBO (S-DIBO), and
k, 1, m, and p are each independently an integer of 0 to 3, provided that all of them are not 0 at the same time.