Patent ID: 11896674
Assignee: SUZHOU RIBO LIFE SCIENCE CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 11:
12. The siRNA conjugate according to claim 1, wherein the sense strand comprises the nucleotide sequence shown in SEQ ID NO: 3 or SEQ ID NO: 4; and the antisense strand comprises any nucleotide sequence selected from the group consisting of the nucleotide sequences shown in SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8:, (SEQ ID NO: 3)

5′-GAAAGUAUGUCAACGAAUU-3′,

 

(SEQ ID NO: 4)

5′-GAAAGUAUGUCAACGAAUA-3′,

 

(SEQ ID NO: 5)

5′-AAUUCGUUGACAUACUUUCUU-3′,

 

(SEQ ID NO: 6)

5′-AAUUCGUUGACAUACUUUCCA-3′,

 

(SEQ ID NO: 7)

5′-UAUUCGUUGACAUACUUUCUU-3′,

 

(SEQ ID NO: 8)

5′-UAUUCGUUGACAUACUUUCCA-3′.