Patent ID: 11958826
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 9:
10. A method of making the 6′-(2-chlorophenyl)-2′-ethoxy-3,4′-bipyridine-3′-carbonitrile compound of claim 1, the method comprising:
adding a mixture of 1-(2-chlorophenyl) ethan-1-one and 3-pyridine carboxaldehyde to a solution of a sodium ethoxide in an absolute ethanol with stirring to obtain a first reaction mixture;
adding malononitrile to the first reaction mixture to obtain a second reaction mixture;
irradiating the second reaction mixture followed by cooling to room temperature to obtain a solid precipitate;
purifying the solid precipitate by filtering and recrystallization using the absolute ethanol; and
obtaining the 6′-(2-chlorophenyl)-2′-ethoxy-3,4′-bipyridine-3′-carbonitrile compound.