Patent ID: 11865538
Assignee: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.
Field: Measurement (Instruments)
Classification: CPC B  G  H | IPC B  G  H

Claim 11:
12. A biological detection method of a biological detection device, wherein the biological detection device comprises a biological detection chip and an opposite substrate, cell-assembled with the biological detection chip to form a culture cavity between the biological detection chip and the opposite substrate, wherein the biological detection chip comprises:
a first base substrate; and
a plurality of detection units arranged in an array along a row direction and a column direction on the first base substrate;
wherein each of the plurality of detection units comprises a thin film transistor and an electrode, the thin film transistor is on the first base substrate and comprises a gate electrode, a source electrode, and a drain electrode, and the electrode is on a side of the thin film transistor away from the first base substrate and is electrically connected to the drain electrode, and
the electrode is configured to carry a biological material to be detected,
the plurality of detection units comprise stimulation units and receiving units, each of the stimulation units is configured to apply a stimulation voltage through the electrode, and each of the receiving units is configured to receive an electrophysiological signal through the electrode,
the biological detection chip further comprises: a plurality of gate lines; and a plurality of data lines arranged to intersect the plurality of gate lines,
each of the plurality of gate lines and the gate electrodes of the detection units in a same row are connected and are on a same layer, and each of the plurality of data lines and the source electrodes of the detection units in a same column are connected and are on a same layer,
the plurality of data lines comprise a first data line and a second data line, the first data line is connected with source electrodes of receiving units belonging to one column of detection units, and the second data line is connected with source electrodes of stimulation units belonging to the column of detection units,
the first data line is disposed at a first side of the column of detection units, and the second data line is disposed at a second side of the column of detection units, the second side is opposite to the first side,
two adjacent columns of detection units are provided with one first data line and one second data line therebetween, and
the biological detection method comprises:
cultivating the biological material to be detected on the electrode on the biological detection chip, the biological material to be detected covering at least part of the detection units;
cell-assembling the biological detection chip and the opposite substrate;
introducing a detection reagent into the culture cavity; and
using the detection units covered by the biological material to be detected to detect an influence of the detection reagent on the biological material to be detected.