Patent ID: 11857605
Assignee: BILLION KING INTERNATIONAL LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 7:
8. The thiosuccinyl-crosslinked hemoglobin conjugate of claim 1, wherein R1 is a moiety of Formula 2:, wherein n is a whole number selected from the group consisting of 0, 1, 2, 3, and 4;
R for each instance is independently selected from the group consisting of hydrogen, alkyl, aralkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl;
R2 is hydrogen, alkyl, aralkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —N(R4)2, —NH(C═O)R4, or —NH(C═O)N(R4)2;
R3 is hydrogen, alkyl, aralkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, —CO2R4, —(C═O)NHR4, —OR4, or —N(R4)2; and
R4 for each instance is independently selected from the group consisting of hydrogen, alkyl, aralkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl;
or R1 is a moiety selected from the group consisting of:, N5-(1-((carboxymethyl)amino)-1-oxo-3λ3-propan-2-yl)glutamine or a pharmaceutically acceptable salt thereof, wherein m is a whole number selected from 1-1,000.