Patent ID: 11963951
Assignee: XSPRAY PHARMA AB
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 14:
15. A composition, consisting of particles consisting of:
(i) a protein kinase inhibitor having a degree of amorphicity of 100% in an amount of from about 10% by weight to about 70% by weight of the particles; and
(ii) copolyvidone; and
(iii) at least one pharmaceutically acceptable solubilizer selected from the group consisting of a d-α-tocopherol acid polyethylene glycol 1000 succinate, a PEG-40 hydrogenated castor oil, a PEG-35 castor oil, a PEG-40 stearate, a hard fat, a polyoxylglyceride, a PEG-8 caprylic/capric glyceride, and a poloxamer;
wherein the protein kinase inhibitor is axitinib, axitinib hydrate, axitinib solvate, axitinib salt, or combinations thereof.