Patent ID: 11872328
Assignee: AZRIELI COLLEGE OF ENGINEERING JERUSALEM
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method for reducing or treating post-operative adhesions in a target site within a body of a subject, the method comprising:
introducing an applicator into a target site within a body of a subject, wherein the applicator is configured for applying an anti-adhesive composition to an implanted medical device fixed and deployed in the target site; and
applying in situ the anti-adhesive composition onto the implanted medical device, wherein said method is performed during or following an interventional medical procedure, and
wherein said applying in situ the anti-adhesive composition onto the implanted medical device comprises the following steps:
a. spreading, onto the implanted medical device, a first composition comprising an anti-adhesive substance, wherein the anti-adhesive substance is a viscous liquid comprising alginate that has been partially crosslinked using calcium gluconate, such that the alginate has a Ca2+ concentration of about 0.25-3% w/v; and
b. applying, onto the first composition, a second composition comprising a bivalent cation crosslinker, thereby transforming the viscous liquid into a gel.