Patent ID: 11932697
Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  G  A | IPC C  G

Claim 0:
1. A polypeptide comprising an antigen binding domain and a carrying moiety, the carrying moiety having an inhibiting domain that inhibits the antigen binding activity of the antigen binding domain, and the antigen binding domain having a shorter half-life in blood than that of the carrying moiety, wherein
the antigen binding domain comprises a single-domain antibody or is a single-domain antibody,
the inhibiting domain comprises a VL,
the antigen binding activity of the single-domain antibody is inhibited by the VL, and
the antigen binding domain and/or inhibiting domain is capable of being released from the polypeptide.