Patent ID: 11921115
Assignee: OPKO DIAGNOSTICS, LLC
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 24:
25. The method of claim 19, wherein the method further comprises determining the quantity of a second prostate antigen in the sample from the subject, wherein the second prostate antigen is human kallikrein 2 (hK2), and the method comprises:
1) Performing a second immunoassay on the sample using a second capture antibody, a second tracer antibody, and/or second blocker antibodies to generate a second signal for detecting the quantity of the second prostate antigen in the sample;
2) performing the second immunoassay on a second set of prostate antigen standards using the second capture antibody, second tracer antibody, and/or second blocker antibodies to generate a second set of signals, wherein each intermediate standard of the second set of prostate antigen standards is equidistant from the standard above and below it on a logarithmic scale, wherein the quantity of the smallest non-zero standard of the second set of prostate antigen standards is below the limit of quantification of the second immunoassay, and wherein the largest standard of the second set of prostate antigen standards is less than or equal to 8 ng/mL hK2; and
3) comparing the second signal obtained in the sample to the second set of signals to determine the quantity of second prostate antigen in the sample.