Patent ID: 11965886
Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 0:
1. A method of immobilizing an animal cell on a support, the method comprising
a) providing a compound or salt thereof comprising two, three or four hydrophobic domains attached to a hydrophilic domain,
wherein the two, three or four hydrophobic domains are independently covalently bound to said hydrophilic domain, and
wherein the two, three or four hydrophobic domains each comprise cholesterol, and wherein the hydrophilic domain comprises a polyethylene glycol (PEG) moiety, and
wherein the compound comprises a covalently linked linking group, wherein the linking group is biotin;
b) contacting an animal cell with the compound under conditions allowing the interaction of the compound with the membrane of the cell, thereby immobilizing the linking group on the surface of the cell; and
c) contacting the linking group immobilized on the cell with a support capable of binding the linking group, thereby immobilizing the cell on the support.