Patent ID: 11866508
Assignee: AMGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 2:
3. The method of claim 1, wherein the mesothelin binding domain comprises a heavy chain variable domain and a light chain variable domain, each comprising at least 90% identity to the heavy chain variable domain and the light chain variable domain selected from the group consisting of:
a) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 86 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 72;
b) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 87 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 73;
c) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 88 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 74;
d) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 88 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 75;
e) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 89 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 76;
f) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 90 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 77;
g) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 91 and the light chain variable domain comprising SEQ ID NO: 78;
h) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 92 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 79;
i) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 92 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 80;
j) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 92 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 81;
k) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 93 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 82; and
l) the heavy chain variable domain comprising the sequence set forth in SEQ ID NO: 94 and the light chain variable domain comprising the sequence set forth in SEQ ID NO: 83.