Patent ID: 11884948
Assignee: PYRONE SYSTEMS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A method of producing a polyketide in a peroxisome, the method comprising:
providing a fatty acid to a genetically modified microorganism, wherein the genetically modified microorganism is a yeast or a fungus, wherein the microorganism comprises a biosynthetic enzyme targeted to the peroxisome in the microorganism, wherein the biosynthetic enzyme is capable of catabolizing the fatty acid into the polyketide, wherein the biosynthetgic enzyme is an acyl-CoA oxidase, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, beta-ketothiolase, thiolase, acyl-CoA synthase, polyketide synthase, cannabidiolic acid synthase, tetrahydrocannabidiolic acid, olivetolic acid synthase, tetraketide synthase, TKS 1, or TKS 1 p;
culturing the microorganism under conditions sufficient to produce the polyketide in the peroxisome; and
isolating the polyketide.