Patent ID: 11890392
Assignee: GUANGZHOU BEOGENE BIOTECHNOLOGY CO., LTD.
Field: Medical technology (Instruments)
Classification: CPC A  C | IPC A  C

Claim 6:
7. The method of claim 5, wherein the hemostatic starch microspheres in step 2) are prepared by the steps of: adding purified water to a certain amount of soluble starch and mixing thoroughly to form a starch solution, adjusting pH of the starch solution with anhydrous sodium carbonate, heating and stirring the starch solution with a magnetic stirrer to gelatinize until the starch solution is transparent, thereby obtaining a gelatinized starch solution, and cooling the gelatinized starch solution for later use; adding purified water to a certain amount of cross-linking agent and stirring and dissolving the cross-linking agent with a magnetic stirrer to obtain a cross-linking agent solution, then pouring the cross-linking agent solution into the gelatinized starch solution and stirring evenly to obtain a prepared starch solution; and adding a certain amount of soybean oil in a three-necked flask, then adding an emulsifier thereto, heating the three-necked flask in a constant temperature water bath device until the emulsifier is completely dissolved, cooling the three-necked flask to 45° C., then under mechanical stirring adding the prepared starch solution slowly, completing a reaction at 45° C. after dropwise addition of the prepared starch solution, then subjecting a reaction solution to centrifugal separation to obtain a solution with oil phase and water phase separated, removing the oil phase, and washing precipitate alternately with absolute ethanol, distilled water, and acetone, and then freeze-drying the precipitate to obtain the hemostatic starch microspheres.