Patent ID: 11874272
Assignee: FIRMENICH SA
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 10:
11. A method,
wherein the method identifies compounds having the ability to prevent, treat, or reduce malodor development on body surfaces, the method comprising the steps of:
a. contacting a subject with a test compound;
b. collecting a sample comprising at least one malodor causing volatile acid compound from a sample of clothing obtained from a subject;
c. extracting the at least one malodor causing volatile acid compound from the collected sample of the subject's clothing with a solvent;
d. forming an ester of the at least one malodor causing volatile acid compound, wherein the ester is an ester selected from the group consisting of methyl esters, ethyl esters, propyl esters, and butyl esters;
e. extracting the ester of the at least one malodor causing volatile acid compound, thereby forming an extracted sample, and
f. determining, in the extracted sample, the amount of at least one ester of the malodor causing volatile acid compound selected from the group consisting of: 3-methyl-2-hexenoic acid (3M2H), and 3-hydroxy-3-methylhexanoic acid (HMHA),

wherein the determining step is performed by GC-MS/MS, and
wherein the test compound prevents, treats, or reduces malodor development on body surfaces if the amount of the extracted ester of the at least one malodor causing volatile acid compound is lower in the sample collected from the subject contacted with the test compound compared to the amount of the extracted ester of the at least one malodor causing volatile acid compound in a sample collected from a non-treated subject.