Patent ID: 11958889
Assignee: JANSSEN PHARMACEUTICA NV
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 13:
14. A liposome, comprising:
a. a tau peptide comprising the amino acid sequence of SEQ ID NO: 28, wherein the tau peptide is presented on the surface of the liposome;
b. a helper T cell epitope having an amino acid sequence selected from the group consisting of SEQ ID NOs: 13, 14 or 15,
c. a lipidated CpG oligonucleotide having the nucleotide sequence selected from the group consisting of SEQ ID NO:18, wherein the CpG oligonucleotide is covalently linked to at least one cholesterol via a linker; and
d. monophosphoryl lipid A (MPLA).