Patent ID: 11918996
Assignee: GENECAPTURE, INC.
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 0:
1. An integrated cartridge for sample homogenization, nucleic acid fragmentation, and nucleic acid detection, the integrated cartridge comprising:
a main housing comprising a sample inlet, a sample well, and a detection chamber, the sample inlet comprising a lumen, the lumen extending between an outer surface of the integrated cartridge and the sample well;
a sonication feature comprising a sonication chamber configured to receive a sample fluid, the sonication feature extending sufficiently outwardly from the main housing to space the sonication chamber from the main housing;
wherein the sonication feature is suspended from the main housing by a coupling positioned between the main housing and the sonication feature, the coupling comprising a gasket and at least one conduit extending therethrough; and
a fluidic path for directing a sample fluid through the integrated cartridge, the fluidic path originating at the sample inlet and extending through the sample well, through the gasket and into the sonication chamber, back through the gasket and into the main housing, and through the detection chamber.