Patent ID: 11896417
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  G | IPC A  G

Claim 0:
1. A method for quantifying blood flow through a portion of a body, the method comprising:
introducing a single tracer into the body;
acquiring, via positron emission tomography (PET), a first set of images of at least a portion of the body, wherein the first set of images is acquired at a first plurality of predetermined time intervals;
based on the first set of images, determining an intensity of the tracer in the at least the portion of the body as a function of time;
modeling the intensity of the tracer in the at least the portion of the body as a function of time using a time-varying kinetic model; and
based on the time-varying kinetic model of the single tracer, quantifying (1) the blood flow through the at least the portion of the body and (2) one or more of a glucose metabolism, an uptake of amino acid transporters, an amyloid load, or an expression of somatostatin receptors in the at least the portion of the body.