Patent ID: 11898202
Assignee: GENOMILL HEALTH OY
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 11:
12. Method according to claim 1, wherein at least one of the first probe or the second probe or the bridge oligo or bridge oligo complex comprises a recognition sequence for an endonuclease and wherein (a) amplifying nucleic acids from the one or more ligated ligation complexes in step (ix) is performed using rolling circle amplification with a strand-displacing polymerase, followed by (b) optionally subjecting the amplified one or more single-stranded concatemeric sequence obtained to annealing with a specific oligonucleotide containing said recognition sequence wherein said specific oligonucleotide anneals with the recognition sequence such that a recognition site for said endonuclease is obtained, and (c) optionally cleaving the amplified one or more single-stranded concatemeric sequence obtained or the annealed complexes obtained with said endonuclease.