Patent ID: 11942223
Assignee: IMMUNEERING CORPORATION
Field: Computer technology (Electrical engineering)
Classification: CPC G  A | IPC G

Claim 35:
36. A system for analyzing sets of genes, the system comprising:
a processor; and
a memory having instructions stored thereon, wherein the instructions, when executed by the processor, cause the processor to:
(a) identify a first gene set corresponding to the disease, the first gene set comprising differentially expressed genes of cells indicative of the disease as compared to cells not indicative of the disease, wherein the first gene set is represented as a first numeric vector comprising weighted values corresponding to gene expression data of the differentially expressed genes of the first gene set; and
(b) for each of a plurality of candidate therapies:
(i) identify a second gene set corresponding to the candidate therapy, wherein the second gene set is represented as a second numeric vector comprising weighted values corresponding to gene expression data of differentially expressed genes; and
(ii) compute a per-gene enrichment statistic for each gene of a subset of the first gene set using the first numeric vector and the second numeric vector.