Patent ID: 11959105
Assignee: QUANTUM-SI INCORPORATED
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A modified recombinant DNA polymerase based on SEQ ID NO: 2, comprising a first segment and a second segment, wherein:
the first segment consists of an amino acid sequence corresponding to a first reference segment, said first reference segment consisting of amino acids 197-271 of SEQ ID NO: 2, wherein the amino acid sequence of the first segment is at least 80%, 80-90%, 90-95%, or at least 95% identical to the amino acid sequence of the first reference segment, and wherein the first segment has a higher isoelectric point than the first reference segment; and
the second segment consists of an amino acid sequence corresponding to a second reference segment, said second reference segment consisting of amino acids 443-528 of SEQ ID NO: 2, wherein the amino acid sequence of the second segment is at least 80%, 80-90%, 90-95%, or at least 95% identical to the amino acid sequence of the second reference segment, and wherein the second segment has a higher isoelectric point than the second reference segment.