Patent ID: 11872265
Assignee: MANNKIND CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A method for the delivery of particles to the pulmonary system comprising:
administering to a patient in need of treatment an effective amount of a dry powder composition by inhalation, the dry powder composition comprising:
a phosphodiesterase type 5 (PDE5) inhibitor; and
a pharmaceutically acceptable salt of a heterocyclic compound which has a structure according to Formula 1:, wherein R1 or R2 are independently selected from 4-succinyl-aminobutyl, 4-glutaryl-aminobutyl, 4-maleyl-aminobutyl, 4-fumaryl-aminobutyl, 4-citraconyl-aminobutyl, 4-malonyl-aminobutyl, 4-oxalyl-aminobutyl;
E1 and E2 are NH; and
said salt further comprises a cation.