Patent ID: 11965208
Assignee: BECTON, DICKINSON AND COMPANY
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 19:
20. The method of claim 17, wherein the phenotypic data comprises:
(A) measurement of one or more of the localization, expression intensity, and persistence of expression of the one or more cellular component targets, wherein the one or more cellular component targets comprise one or more endogenous proteins;
(B) measurement of cell death, and wherein the cell death is evaluated by detecting apoptosis markers;
(C) measurement of a dynamic behavior of the one or more single cells as a function of time; and/or
(D) measurement of cellular activation, cellular inhibition, cellular interaction, protein expression, protein secretion, metabolite secretion, changes in lipid profiles, microvesicle secretion, exosome secretion, microparticle secretion, changes in cellular mass, cellular proliferation, changes in cellular morphology, motility, cell death, cell cytotoxicity, cell lysis, cell membrane polarization, establishment of a synapse, dynamic trafficking of proteins, granule polarization, calcium activation, metabolic changes, small molecule secretion, proton secretion, or any combination thereof.