Patent ID: 11884645
Assignee: INFLAZOME LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 18:
19. A prodrug of a compound of formula (I):, or a pharmaceutically acceptable salt or solvate thereof, wherein:
Q is selected from 0 or S;
R1 is a 5-membered heteroaryl group, wherein the 5-membered ring structure consists of one or more carbon atoms, one or more nitrogen atoms and optionally one or more oxygen atoms, wherein R1 is substituted with R6 and R1 may optionally be further substituted;
R2 is a cyclic group substituted at the α and α′ positions, wherein R2 may optionally be further substituted;
R3 is hydrogen, halogen, —OH, —NH2, —CN, —R5, —OR5, —NHR5 or —N(R5)2;
R4 is hydrogen, halogen, —OH, —NH2, —CN, —R5, —OR5, —NHR5 or —N(R5)2; or
R3 and R4 together with the carbon atom to which they are attached may form a 3- to 7-membered saturated or unsaturated cyclic group, wherein the cyclic group may optionally be substituted;
R5 is independently an optionally substituted C1-C4 alkyl group; and
R6 is any group comprising a nitrogen atom.