Patent ID: 11958889
Assignee: AC IMMUNE SA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 5:
6. A liposome, comprising:
a. a tau peptide comprising the amino acid sequence of SEQ ID NO: 2, wherein the tau peptide is presented on the surface of the liposome;
b. a helper T cell epitope having an amino acid sequence selected from the group consisting of SEQ ID NOs:39, 40, 41, 42, and 43;
c. a lipidated CpG oligonucleotide having the nucleotide sequence selected from the group consisting of SEQ ID NO:18 to SEQ ID NO:22, wherein the CpG oligonucleotide is covalently linked to at least one cholesterol via a linker; and
d. monophosphoryl lipid A (MPLA).