Patent ID: 11946058
Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A method of inducing RNA silencing in a plant-chewing or phloem-feeding insect comprising the steps of:
a. providing an oligonucleotide comprising at least one 2′F-ANA-modified nucleotide and at least one 2′-deoxyribonucleotide, and wherein the 2′F-ANA-modified nucleotides are positioned according to any of Formula 2-16, and having the sequence of SEQ ID NO: 39-46, SEQ ID NO: 48-69 and SEQ ID NO: 71-76 to the insect in a manner whereby the insect to ingests the oligonucleotide, thereby inducing RNA silencing.