Patent ID: 11946066
Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 10:
11. The viral vector of claim 1,
wherein the polynucleotide is capable of being replicated when the first protein and the second protein are in active states,
wherein the first protein and the second protein are in active states when the protease inhibitor is absent,
wherein the polynucleotide is capable of being replicated when the protease inhibitor is absent,
wherein the polynucleotide is not capable of being replicated when the first protein and the second protein are in inactive states,
wherein the first protein and the second protein are in inactive states when the protease inhibitor is present,
wherein the polynucleotide is not capable of being replicated when the protease inhibitor is present,
wherein the first protein and the second protein are in inactive states at a threshold concentration of the protease inhibitor, and/or
wherein the polynucleotide is not capable of being replicated at a threshold concentration of the protease inhibitor.