Patent ID: 11957647
Assignee: OREXO AB
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 17:
18. A pharmaceutically-acceptable composition in the form of an amorphous spray-dried powder, comprising a mixture of:
(a) epinephrine (adrenaline) or a pharmaceutically-acceptable salt thereof in a dosage amount of between about 0.5 and about 2 mg when calculated as the free base;
(b) a pharmaceutically-acceptable carrier material, which carrier material comprises a combination of trehalose and maltodextrin 19DE, in a ratio of between about 3:1 and 1:3 by weight;
(c) about 0.75% to about 3% by weight of sucrose monolaurate; and
(d) less than about 5% of water;, wherein the particle size distribution of the powder comprises a D10 above about 10 μm and a D90 below about 100 μm.