Patent ID: 11942209
Assignee: I.D. THERAPEUTICS LLC
Field: Medical technology (Instruments)
Classification: CPC G  Y | IPC G

Claim 6:
7. A method of optimizing treatment of a transplant recipient, comprising:
administering at least one immunosuppressant medication to a transplant recipient as a part of an immunosuppressant treatment regimen;
providing the transplant recipient with a reprogram mable medication monitor capable of providing usage data regarding the transplant recipient's compliance with the immunosuppressant treatment regimen, the immunosuppressant treatment regimen being established based on a medication compliance pattern of the transplant recipient, wherein the compliance pattern is a statistical pattern derived from a plurality of data points gathered over a period of time of not less than one week, where the data points include doses missed, doses taken early, doses taken late, and taken on time,
the medication monitor including:
a housing body that includes a housing for containing medication or medication packaging, the housing body defining an opening to accommodate insertion and removal of the medication or of the medication packaging, and
a removal sensor that senses at least one of (1) removal of the medication or of the medication packaging and (ii) opening of the housing body;

collecting the usage data from the medication monitor at a central server over a predetermined period of time;
determining safety and efficacy of the immunosuppressant treatment regimen;
determining the transplant recipient's pattern of compliance with the immunosuppressant treatment regimen based on the usage data collected from the medication monitor;
obtaining diagnostic test results from a biomarker device, the diagnostic test results being indicative of a level of immunosuppression of the transplant recipient to the immunosuppressant treatment regimen over the predetermined period of time,
the biomarker device being configured to be implanted in the transplant recipient or provided external to the transplant recipient;

correlating the transplant recipient's pattern of compliance and the transplant recipient's diagnostic test results with patterns of compliance and diagnostic test results from a population of transplant recipients to obtain a correlation;
outputting at least one recommendation based on the correlation and based on the safety and efficacy of the immunosuppressant treatment regimen, the at least one recommendation including replacing the at least one immunosuppressant medication used in the immunosuppressant treatment regimen with at least one different medication; and
adjusting and administering the immunosuppressant treatment regimen of the transplant recipient based on the at least one recommendation.