Patent ID: 11891668
Assignee: UNIVERSITY OF KANSAS
Field: Measurement (Instruments)
Classification: CPC B  C  A  G | IPC A  B  C  G

Claim 0:
1. A composition for isolating an extracellular vesicle, the composition comprising a plurality of magnetic particles, each magnetic particle comprising:
a core particle, wherein said core particle is coated with a layer comprising graphene-oxide nanosheets covalently bonded to the core particle, further comprising at least one polydopamine polymer coupled with the graphene-oxide nanosheets; and
a targeting moiety extending from the core particle via a photocleavable linker, wherein said targeting moiety is coupled to at least one polydopamine polymer, and said photocleavable linker connecting the magnetic particle and the targeting moiety, wherein the targeting moiety specifically binds to an extracellular vesicle surface marker for isolating said extracellular vesicle.