Patent ID: 11865176
Assignee: DANA-FARBER CANCER INSTITUTE, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of treating a tumor in a subject comprising administering to said subject a CDK4/6 inhibitor and an immune checkpoint inhibitor, wherein the CDK4/6 inhibitor is palbociclib, and wherein the immune checkpoint inhibitor is an anti-PD-1 antibody, wherein the anti-PD-1 antibody is administered 3 times a week, wherein the CDK4/6 inhibitor is administered for 2 or 3 days prior to administration of the checkpoint inhibitor, and wherein the CDK4/6 inhibitor is administered for 3 days on followed by 4 days off, wherein the tumor is a colorectal tumor.