Patent ID: 11969483
Assignee: NANOMEDTRIX, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 9:
10. A method for sequential imaging and/or imaging diagnostic or therapeutic cells in a mammal, comprising:
a) introducing to a mammal a composition comprising mesoporous silica nanoparticles (MSNs), said MSNs being covalently functionalized with at least one material selected from the group consisting of a lanthanide, a fluorophore and, an agent detectable by ultrasound, whereby the MSNs are capped with gelatin or a synthetic phospholipid bilayer; and further providing that the MSNs are covalently linked with a bladder cancer cell specific Cyc6 peptide (Cyc6); and
b) detecting the composition in the mammal.