Patent ID: 11938474
Assignee: HAMILTON BONADUZ AG
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 15:
16. A method for determining the dosing quality of a dispensing sequence of a pipetting device working according to the air displacement principle, where the dispensing sequence comprises at least one pulsed single-volume dispensing run of a dosing liquid with a target single volume to be dispensed of less than 1 which through generation of an overpressure pulse of less than 50 ms pulse duration in a compressible working gas present between a pipetting piston and a dosing liquid supply in the pipetting channel of the pipetting device is delivered from the dosing liquid supply, where the method comprises the following steps:
determining a target residual quantity value, which represents a residual quantity of dosing liquid remaining in the pipetting channel at the end of the dispensing sequence,
determining a working gas pressure associated to the represented target residual quantity which is required in order to maintain the target residual quantity in the pipetting channel in a predetermined state,
actuating a piston drive for adjusting the determined working gas pressure in the pipetting channel,
after adjustment of the determined working gas pressure in the pipetting channel: acquiring the piston position of the pipetting piston,
comparing the acquired piston position with a target piston position associated to at least one of the represented target residual quantity and to the determined working gas pressure, and
producing an output representing the determined dosing quality as a function of the comparison result representing the dosing quality of the dispensing sequence.