Patent ID: 11964002
Assignee: VIB VZW
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 14:
15. A method of making the dried pharmaceutically acceptable formulation of claim 1, the method comprising:
separating, from a culture medium in which a recombinant fungal host cell has been cultured, macromolecules smaller than 5 kDa so as to obtain a separated culture medium having a lowered concentration of macromolecules smaller than 5 kDa as compared to the culture medium immediately prior to the separation; and
drying the separated culture medium so as to produce the dried formulation of claim 1,
wherein the separated culture medium comprises a polypeptide fused to an Fc domain secreted into the culture medium by the recombinant fungal host cell; and
wherein the polypeptide is exogenous to the recombinant fungal host cell.