Patent ID: 11963786
Assignee: UNIVERSITY OF MIAMI
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A

Claim 0:
1. A method for determining cognitive impairment (CI) implemented by at least one processor, the method comprising:
forming a database including a quantification of retinal structure and retinal function of a plurality of eyes associated with a plurality of patients, the quantification providing a baseline cognitive impairment (CI) reference;
receiving an electroretinogram (ERG) of a retina of a patient;
determining a measure of functionality of neurons in the retina based on the ERG;
receiving a retinal image of the retina;
skeletonizing the retinal image as a skeletonized retinal image;
determining a structural measure of the first retina based on
a generalized dimension spectrum and singularity spectrum of the skeletonized retinal image, and
a lacunarity parameter of the skeletonized retinal image;

comparing the measure of functionality and the structural measure of the retina to the database; and
determining a level of cognitive impairment of the patient based on the comparing.