Patent ID: 11873339
Assignee: PIERRE FABRE MEDICAMENT
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C

Claim 0:
1. An isolated antibody, or antigen-binding fragment thereof, that binds to a first group of C10orf54 proteins or chimeric proteins designated CC1 (SEQ ID NO: 1079), CC4 (SEQ ID NO: 1245), CC5 (SEQ ID NO: 1246), CC8 (SEQ ID NO: 1249), and CC10 (SEQ ID NO: 1251), and does not bind to a second group of C10orf54 proteins or chimeric proteins designated CC2 (SEQ ID NO: 1243), CC3 (SEQ ID NO: 1244), CC6 (SEQ ID NO: 1247), CC7 (SEQ ID NO: 1248), and CC9 (SEQ ID NO: 1250);
wherein the antibody is the antibody 230A, comprising:
a heavy chain variable domain comprising the following three CDRs, respectively CDR-H1 having the sequence SEQ ID NO: 1302, CDR-H2 having the sequence SEQ ID NO: 1365 and CDR-H3 having the sequence SEQ ID NO: 1402, and a light chain variable domain comprising the following three CDRs, respectively CDR-L1 having the sequence SEQ ID NO: 1455, CDR-L2 having the sequence SEQ ID NO: 1103 and CDR-L3 having the sequence SEQ ID NO: 1505.