Patent ID: 11857565
Assignee: SEAGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A

Claim 1:
2. The Ligand Drug Conjugate compound of claim 1, wherein each of the drug linker moieties has the structure of:, or a pharmaceutically acceptable salt thereof, wherein
R2 is methyl; and
R1 is C3-C9 alkyl, or
R1 is (C3-C6 carbocyclyl)-alkylene- of up to 9 total carbon atoms, or
R1 is —(C2-C6 alkylene)-X—R4, wherein X is an amide or carbamate functional group and R4 is C1-C6 alkyl;
with the proviso that the total number of carbon atoms in R2 and the (carbocyclyl)alkyl(ene) moiety of R1 is between 4 and 10.