Patent ID: 11946058
Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 8:
9. A method of controlling a plant-chewing or phloem-feeding insect, comprising the steps of:
a. providing an oligonucleotide comprising at least one 2′F-ANA-modified nucleotide and at least one 2′-deoxyribonucleotide, and wherein the 2′F-ANA-modified nucleotides are positioned according to any of Formula 2-16, and having a sequence selected from the group consisting of SEQ ID NO: 39-46, SEQ ID NO: 48-69 and SEQ ID NO: 71-76 in a manner whereby the insect to ingests the oligonucleotide, thereby inducing RNA silencing and a detrimental effect to the insect.