Patent ID: 11905327
Assignee: NANJING LEGEND BIOTECH CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 12:
13. The anti-TIGIT construct of claim 10, wherein the full-length antibody specifically recognizes PD-1, and wherein the full-length antibody comprises heavy chain complementarity determining regions (HC-CDRs) and light chain complementarity determining regions (LC-CDRs) of:
(a) a heavy chain variable domain (VH) comprising the amino acid sequence of SEQ ID NO: 385, and a light chain variable domain (VL) comprising the amino acid sequence of SEQ ID NO: 386;
(b) a VH comprising the amino acid sequence of SEQ ID NO: 387, and a VL comprising the amino acid sequence of SEQ ID NO: 388; or
(c) a VH comprising the amino acid sequence of SEQ ID NO: 406, and a VL comprising the amino acid sequence of SEQ ID NO: 407.