Patent ID: 11959924
Assignee: ADURO BIOTECH HOLDINGS, EUROPE B.V.
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 1:
2. The method of claim 1, wherein the APRIL, binding antibody comprises:
i) the VH domain comprises at least 95% sequence identity to SEQ ID NO: 23 and comprises CDR sequences set forth in SEQ ID NOs: 25-27, and the VL domain comprises at least 95% sequence identity to SEQ ID NO: 24 and comprises CDR sequences set forth in SEQ ID NOs: 28-30,
ii) the VH domain comprises at least 95% sequence identity to SEQ ID NO: 3 and comprises CDR sequences set forth in SEQ ID NOs: 5-7, and the VL domain comprises at least 95% sequence identity to SEQ ID NO: 4 and comprises CDR sequences set forth in SEQ ID NOs: 8-10,
iii) the VH domain comprises at least 95% sequence identity to SEQ ID NO: 13 and comprises the CDR sequences set forth in SEQ ID NOs: 15-17, and the VL domain comprises at least 95% sequence identity to SEQ ID NO: 14 and comprises the CDR sequences set forth in SEQ ID NOs: 18-20,
iv) the VH domain comprises at least 95% sequence identity to SEQ ID NO: 33 and comprises the CDR sequences set forth in SEQ ID NOs: 35-37, and the VL domain comprises at least 95% sequence identity to SEQ ID NO: 34 and comprises the CDR sequences set forth in SEQ ID NOs: 38-40, or
v) the VH domain comprises at least 95% sequence identity to SEQ ID NO: 43 and comprises the CDR sequences set forth in SEQ ID NOs: 45-47, and the VL domain comprises at least 95% sequence identity to SEQ ID NO: 44 and comprises the CDR sequences set forth in SEQ ID NOs: 48-50.