Patent ID: 11951173
Assignee: BLISS BIOPHARMACEUTICAL (HANGZHOU) CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 2:
3. An ADC or a pharmaceutically acceptable salt thereof, comprising:
a monoclonal antibody conjugated to a cytotoxic drug by a chemical linker, wherein the monoclonal antibody comprises two identical long chains and four identical short chains, wherein:
(a) each of the long chains comprises the sequence of SEQ ID NO:1 and each of the short chains comprises the sequence of SEQ ID NO:2; or
(b) each of the long chains comprises the sequence of SEQ ID NO:13 and each of the short chains comprises the sequence of SEQ ID NO:14; or
(c) each of the long chains comprises the sequence of SEQ ID NO:15 and each of the short chains comprises the sequence of SEQ ID NO:16; or
(d) each of the long chains comprises the sequence of SEQ ID NO:17 and each of the short chains comprises the sequence of SEQ ID NO:18; or
(e) each of the long chains comprises the sequence of SEQ ID NO:21 and each of the short chains comprises the sequence of SEQ ID NO:22; or
(f) each of the long chains comprises the sequence of SEQ ID NO:23 and each of the short chains comprises the sequence of SEQ ID NO:24.