Patent ID: 11926851
Assignee: CARBIOS
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 0:
1. An esterase which (i) has at least 95% identity to the full length amino acid sequence set forth in SEQ ID NO: 1, and (ii) has at least one amino acid substitution at a position corresponding to residues selected from Q182, T11, R12, A14, W69, R73, A205, N214, A215, A216, 1217, F238, V242, D244, P245, A246, L247, D94, R138, D158, F187, P10, L15, D18, N87, S88, S95, Q99, K159, A174, A125, and 5218 wherein the positions are numbered by reference to the amino acid sequence set forth in SEQ ID NO: 1, and (iii) exhibits increased polyester degrading activity and/or an increased thermostability compared to the esterase of SEQ ID NO: 1.