Patent ID: 11872023
Assignee: ANGIONICA SP. Z O.O.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A method of assessment of oscillatory function of skin microcirculation, the method comprising:
illumination of a selected location on non-hairy skin of a human subject in a resting steady condition without any blockage or stimulation of blood flow with exciting light capable of inducing skin NADH fluorescence signal for a period of time;
simultaneously with said illumination detecting, measuring and recording as a function of time the induced NADH fluorescence signal emitted from the selected location to obtain a time course of the NADH fluorescence signal intensity in said period of time; and
computer implemented steps of:
fitting of a baseline about which the NADH fluorescence signal oscillates to the time course of the NADH fluorescence signal; and
determination of a mean squared error of deviation of the NADH fluorescence signal from the fitted baseline as a parameter of oscillatory function of the skin microcirculation.