Patent ID: 11911741
Assignee: SARTORIUS STEDIM BIOTECH GMBH
Field: Chemical engineering (Chemistry)
Classification: CPC B  A  C | IPC A  B  C

Claim 0:
1. A method for producing a diatomaceous earth composition with a low endotoxin content, comprising the following steps:
(a) providing calcined diatomaceous earth particles;
(b) mixing the calcined diatomaceous earth particles with water in a mass ratio of 1:1.0 to 1:2.0, thereby obtaining an agglomerated mixture of calcined diatomaceous earth particles and water;
(c) sealing the agglomerated mixture of calcined diatomaceous earth particles and water obtained in step (b) in a water-impermeable and γ-sterilizable packaging, thereby obtaining a sealed agglomerated mixture of calcined diatomaceous earth particles and water;
(d) sterilizing the sealed agglomerated mixture of calcined diatomaceous earth particles and water obtained in step (c) by exposure to γ-radiation, thereby obtaining a diatomaceous earth composition with an endotoxin content of equal to or less than 0.5 EU/mL; and
(e) optionally removing the packaging from the diatomaceous earth composition obtained in step (d).