Patent ID: 11951212
Assignee: VERTEX PHARMACEUTICALS INCORPORATED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 27:
28. The pharmaceutical composition of claim 1, wherein the tablet comprises:
125 mg of a first solid dispersion which comprises 80 wt % of amorphous Compound 1 relative to the total weight of the first solid dispersion and 20 wt % of polymer relative to the total weight of the first solid dispersion,
187.5 mg of a second solid dispersion which comprises 80 wt % of amorphous Compound 2 relative to the total weight of the second solid dispersion, 19.5 wt % of polymer relative to the total weight of the second solid dispersion, and 0.5 wt % of sodium lauryl sulfate relative to the total weight of the second solid dispersion,
30 wt % to 50 wt % filler,
1 wt % to 10 wt % disintegrant, and
1 wt % lubricant.