Patent ID: 11858910
Assignee: SUNSHINE LAKE PHARMA CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC C

Claim 0:
1. A compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, a pharmaceutically acceptable salt or a prodrug thereof,, , wherein
L is —C(═O)—, —C(═S)— or —S(═O)2—;
R1 is C1-C6 alkyl, C3-C8 cycloalkyl, 3-8 membered heterocyclyl, C6-C10 aryl or 5-10 membered heteroaryl, wherein R1 is optionally substituted with 1, 2, 3, 4 or 5 substituents independently selected from R1a, R1b, R1c, R1d and R1e;
each R1a, R1b, R1c, R1d and R1e is independently H, F, Cl, Br, I, —CN, —NO2, —NH2, —OH, —SH, —COOH, —C(═O)NH2, —C(═O)NHCH3, —C(═O)N(CH3)2, —C(═O)—(C1-C6 alkyl), —C(═O)—(C1-C6 alkoxy), C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 haloalkyl, C1 —C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 alkylamino, hydroxy-substituted C1-C6 alkyl, C3-C8 cycloalkyl, 3-8 membered heterocyclyl, C6-C10 aryl or 5-10 membered heteroaryl;
R2 is H, F, Cl, Br, I, —CN, —NO2, —NH2, —OH, —COOH, —C(═O)NH2, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy or hydroxy-substituted C1-C6 alkyl;
each of R3, R4 and R5 is independently H, F, Cl, Br, I, —CN, —NO2, —NH2, —OH, —COOH, —C(═O)NH2, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy or hydroxy-substituted C1-C6 alkyl;
R6 is H, F, Cl, Br or I;
R7 is H, F, Cl, Br, I, —CN, —NO2, —NH2, —OH, —COOH, —C(═O)NH2, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy or hydroxy-substituted C1-C6 alkyl; and
R8 is H, F, Cl, Br, I, —CN, —NO2, —NH2, —OH, —SH, —COOH, —C(═O)NH2, —C(═O)NHCH3, —C(═O)N(CH3)2, —C(═O)—(C1-C6 alkyl), —C(═O)—(C1-C6 alkoxy), C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 alkylthio, C1-C6 alkylamino, hydroxy-substituted C1-C6 alkyl, C3-C8 cycloalkyl, 3-8 membered heterocyclyl, C6-C10 aryl or 5-10 membered heteroaryl.