Patent ID: 11952363
Assignee: HOFFMANN-LA ROCHE, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 2:
3. A compound according to claim 2, wherein:
R2 is methyl;
R3 is R3a or —COR3b; wherein:
R3 is R3a is piperazinylphenyl ; (hydroxymethyl)piperazinylphenyl; piperazinylpyridinyl; (methylpiperazinyl)pyridinyl; 9-oxa-3 , 7-diazabicyclo[3.3.1]nonanylpyridinyl; ((fluoropyrrolidinyl)amino)pyridinyl; ((pyrrolidinylcarbonyl)piperazinyl)pyridinyl; (((dimethylamino)acetyl)piperazinyl)pyridinyl; piperazinylpyrimidinyl; or ((dimethylamino)acetyl)piperazinylpyrimidinyl;
R3b is piperazinyl-7,8-dihydro-5H-1,6-naphthyridinyl; piperazinyl-3,4-dihydro-1H-isoquinolinyl; piperazinylisoindolinyl; piperazinylphenylamino; 1,2,3,4-tetrahydroisoquinolinyl; or methylpiperidinylpiperidinyl;

and
R4 is methyl or H;
or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof.