Patent ID: 11939386
Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
Field: Pharmaceuticals (Chemistry)
Classification: CPC G  A  C | IPC A  C

Claim 9:
10. The an antibody-drug conjugate of claim 9, wherein the microtubule targeting drug is selected from the group consisting of: monomethyl auristatin E (MMAE), monomethyl auristatin F (MMAF), maytansine derivative DM1 and tubulysin; and/or
the DNA targeting drug is selected from the group consisting of docamycin, and pyrrolo[2,1-c][1,4]benzodiazepine (PBD); and/or
the topoisomerase inhibitor is selected from the group consisting of: 7-ethyl-10-hydroxycamptothecin (SN38), Exatecan and analogs thereof.