Patent ID: 11964048
Assignee: nan
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 20:
21. A method for making an the composition of claim 1, the method comprising
making a pull layer blend and a push layer blend;
horizontally pressing the pull layer blend and the push layer blend into a bilayered tablet core containing a pull layer and a push layer;
coating the bilayered tablet core with ayermeable elastic membrane; and. drilling orifice in the permeable elastic membrane,
wherein the pull layer blend comprises a drug intermediate blend and an extragranular component,
wherein die drug intermediate blend comprises liothyronine or a pharmaceuticallv acceptable salt thereof,
wherein the extragranular component comprises an acid, a gas generating agent, and an osmogen,
wherein the permeable, elastic membrane comprises a copolymer of ethyl acrylate, methyl methacrylate and trimethylammonioethyl methacrylate chloride, and a plasticizer,

wherein the orifice is in fluid communication with the pull layer, and
wherein the composition does not include a semipermeable membrane.