Patent ID: 11923063
Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
Field: Medical technology (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. Apparatus for controlling the delivery of insulin to a subject and comprising:
a first input for receiving neural information recorded from the subject's nervous system and indicative of prospective or actual food and/or drink intake;
a second input for receiving a signal indicative of the subject's blood glucose level;
a processor or processors configured to determine food and/or drink characteristics based on the received neural information, determine an amount of insulin to be delivered based on the measured blood glucose levels and the determined food and/or drink characteristics, and output an insulin pump control signal indicative of the determined amount of insulin; and
a third input for receiving a neural signal recorded from the subject's nerves innervating the liver and/or brown adipose tissue and/or nuclei of the hypothalamus indicative of a subject's insulin sensitivity;
said processor(s) being configured to determine a characteristic of a neural stimulation signal to be applied by a neural stimulation unit using said signal indicative of a subject's insulin sensitivity, and the apparatus comprising a second output for providing neural stimulation unit control signal indicative of said characteristic; and
said neural stimulation unit being configured to apply said neural stimulation signal to efferent sympathetic nerves to the liver and/or brown adipose tissue and/or hypothalamic areas in order to increase or decrease the subject's insulin sensitivity during delivery of the determined amount of insulin.