Patent ID: 11925693
Assignee: nan
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  B | IPC A  B  C

Claim 0:
1. A method of treating melanoma or colon cancer, comprising the step of administering a therapeutically effective dose of a composition for the delivery of immunotherapeutic agents, comprising:
a polymeric nanoparticle comprising:
poly(lactic-co-glycolic)acid (PLGA);
a payload comprising an effective dose of PAM3CSK4, L18-MDP, and IL-2; and
an agonistic anti-CD28 antibody,

wherein:
the polymeric nanoparticle encapsulates the payload,
the antibody is conjugated to the surface of the polymeric nanoparticle, and
the effective dose of the composition comprises IL-2 at a concentration of up to 50 μg/kg body weight and PAM3CSK4 and L18-MDP in a 1:1 weight ratio.