Patent ID: 11875509
Assignee: CASE WESTERN RESERVE UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 6:
7. A system for determining an undersampling error for a magnetic resonance fingerprinting (MRF) pulse sequence comprises:
an input configured to receive the MRF pulse sequence and a reference image;
an undersampling error simulator coupled to the input and configured to:
receive the MRF pulse sequence and reference image;
retrieve a plurality of sets of spatial response functions, wherein each set of spatial response functions is associated with a tissue type in a region of interest of the reference image and each set of spatial response functions is based on a tissue mask of the reference image associated with the tissue type corresponding to the set of spatial response functions;
generate a plurality of signal evolutions based at least on the MRF pulse sequence, each of the plurality of signal evolutions associated with a tissue type for the region of interest in the reference image;
generate an undersampled image for each tissue type using the set of spatial response functions for the tissue type and the signal evolutions for the tissue type;
combine the undersampled image for each tissue to create an undersampled image series;
compare the undersampled image series to an MRF dictionary to determine at least one quantitative parameter;
generate a quantitative map for the at least one quantitative parameter; and
generate an undersampling error for the MRF pulse sequence by comparing the quantitative map and the reference image; and

a display coupled to the undersampling error simulator and configured to display the undersampling error.