Patent ID: 11906514
Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 14:
15. A lateral flow device for detecting the presence of cerebrospinal fluid in a liquid biological sample, the device comprising, in sequential order for lateral flow of a liquid, a sample pad; a conjugate pad; a binding portion; and an absorbent pad;
wherein
a) the sample pad comprises a portion suitable to allow liquid sample flow;
b) the conjugate pad comprises both (A) and (B),
wherein
(A) comprises first plurality of transferrin-binding antibodies conjugated to a first plurality of nanoparticles, and
(B) comprises a plurality of lectin molecules conjugated to a second plurality of nanoparticles, which nanoparticles are free to move laterally along the device when a liquid is present thereon;

c) the binding portion comprises the following separate domains:
a. a domain which comprises a second plurality of transferrin-binding antibodies which are adhered to the surface of the lateral flow device; and
b. a dried blood serum reagent domain adhered to the surface of the lateral flow device.