Patent ID: 11918656
Assignee: PIERRE FABRE MEDICAMENT
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method for treating a cancer selected from the group consisting of breast cancer, lung cancer, and kidney carcinoma, in a person in need thereof, wherein the method comprises administering to said person a therapeutically effective amount of a compound of the following formula:, or a pharmaceutically acceptable salt thereof,
wherein:
R1 is H or OH,
R2 is a (C1-C6)alkyl, COOH, COO—(C1-C6)alkyl or thiazolyl group,
R3 is H or a (C1-C6)alkyl group, and
H-A- is:
a group of formula Het-Alk-, wherein Alk is a (C1-C8)alkanediyl group and is linked to NR3, and Het is a heterocycle optionally substituted by a (C1-C6)alkyl group and containing at least one nitrogen atom linked to a hydrogen atom, or
a group of formula H-Aa-Ab-, wherein Aa is O or NR9 with R9 being H or (C1-C6)alkyl, and Ab is linked to NR3 and is:
a (C1-C8)alkanediyl group,
a —(CH2CH2X1)a1(CH2CH2X2)a2(CH2CH2X3)a3(CH2CH2X4)a4CH2CH2— group with X1, X2, X3 and X4 each independently of one another being O or NR8; a1, a2, a3 and a4 each independently of one another being 0 or 1; and R8 being H or a (C1-C6)alkyl group, or
an aryl-(C1-C8)alkanediyl or heterocycle-(C1-C8)alkanediyl group, said group being optionally substituted by a (C1-C6)alkyl group, the aryl or heterocycle moiety being linked to Aa and the (C1-C8)alkanediyl moiety being linked to NR3.