Patent ID: 11859242
Assignee: CARNEGIE MELLON UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C  G

Claim 9:
10. The genetic recognition reagent of claim 1, having the structure:, where,
each R is independently, a nucleobase of the plurality of nucleobases;
each n is independently an integer ranging from 1 and 8;
each m is independently an integer ranging from 1 and 5;
each R2 is independently: a guanidine-containing group, an amino acid side chain, methyl, ethyl, linear or branched (C3-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C1-C8)hydroxyalkyl, (C3-C8)aryl, (C3-C8)cycloalkyl, (C3-C8)aryl(C1-C6)alkylene, or (C3-C8)cycloalkyl(C1-C6)alkylene; or an amino acid side chain, methyl, ethyl, linear or branched (C3-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C1-C8)hydroxyalkyl, (C3-C8)aryl, (C3-C8)cycloalkyl, (C3-C8)aryl(C1-C6)alkylene, or (C3-C8)cycloalkyl(C1-C6)alkylene, wherein the amino acid side chain, methyl, ethyl, linear or branched (C3-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C1-C8)hydroxyalkyl, (C3-C8)aryl, (C3-C8)cycloalkyl, (C3-C8)aryl(C1-C6)alkylene, or (C3-C8)cycloalkyl(C1-C6)alkylene is substituted with an ethylene glycol unit comprising from 1 to 50 ethylene glycol moieties; —(OCH2—CH2)qOP1; —(OCH2—CH2)q—NHP1; —(SCH2—CH2)q—SP1; —(OCH2—CH2)r—OH; —(OCH2—CH2)r—NH2; —(OCH2—CH2)r—NHC(NH)NH2; or —(OCH2—CH2)r—S—S[CH2CH2]sNHC(NH)NH2, where P1 is H, (C1-C8)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C3-C8)aryl, (C3-C8)cycloalkyl, (C3-C8)aryl(C1-C6)alkylene or (C3-C8)cycloalkyl(C1-C6)alkylene; q is an integer from 0 to 50; r is an integer from 1 to 50, and s is an integer from 1 to 50;
R3 is an unsubstituted fused-ring polycyclic aromatic moiety; and
each of R5, R7, and R8 are, independently H, a guanidine-containing group, an amino acid side chain, or one or more contiguous amino acid residues,

or a pharmaceutically-acceptable salt thereof.