Patent ID: 11866498
Assignee: GENENTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The bispecific antigen-binding molecule of claim 1, wherein:
(a) the FabA comprises a VHA region and a VLA region, wherein the VHA region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 7, and the VLA region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 8;
(b) the FabB1 comprises a VHB1 region and a VLB1 region, wherein the VHB1 region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 41, and the VLB1 region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 49; and
(c) the FabB2 comprises a VHB2 region and a VLB2 region, wherein the VHB2 region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 41, and the VLB2 region comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 49.