Patent ID: 11920136
Assignee: TALLAC THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. An immunomodulating oligonucleotide of formula (D):, , wherein
* and ** indicate the points of attachment within the oligonucleotide;
each T1 is independently O or S;
each T2 is S−;
T3 is a group, wherein † indicates the point of attachment to
L and wherein # indicates the point of attachment to the rest of the oligonucleotide;
L is a group, wherein m is an integer from 0 to 50 and wherein, † indicates the point of attachment to the rest of the oligonucleotide via T3;
Z is 0 or S;
U5′ is —H or halogen;
R5′ is —H or methoxy;
Rc1 is —H or methoxy;
Rg1, Rg2, Rg3, and V are H;
R3′ is methoxy;
R1 is —(CH2)3—OH;
R2 is —H or methyl; and
n is an integer from 0 to 2,
or a pharmaceutically acceptable salt thereof.