Patent ID: 11890370
Assignee: SAHMYOOK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 0:
1. A method for preparing a drug delivery system in the form of microcapsules in which both a drug and nanobubbles are microencapsulated, the method comprising the steps of:
(a) dissolving the drug in an organic solvent, and then mixing it with an oil to prepare a mixed solution;
(b) removing the organic solvent from the mixed solution;
(c) preparing an oil solution containing both the drug and the nanobubbles, by generating the nanobubbles in the mixed solution from which the organic solvent has been removed; and
(d) mixing the oil solution in an aqueous solution containing a surfactant,
wherein the drug delivery system in the form of the microcapsules is prepared by encapsulating the drug together with the nanobubbles, both being contained in the oil,
wherein the drug is a fat-soluble drug, and
wherein the organic solvent is completely removed from the mixed solution using a vacuum or rotary concentrator.