Patent ID: 11878160
Assignee: GALVANI BIOELECTRONICS LIMITED
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A method of treating bronchoconstriction in a patient, the method comprising:
applying an electrical signal by a neuromodulation device partially implanted in the patient and positioned in signaling contact with a pulmonary branch of a vagal nerve of the patient, wherein the neuromodulation device comprises one or more electrodes that apply the electrical signal to afferent A fibers of the vagal nerve of said patient to selectively stimulate neural activity in the afferent A fibers of the vagal nerve in said patient, while not stimulating efferent fibers or afferent Aδ fibers, wherein the electrical signal—has a frequency in the range of 50-150 Hz, and wherein the electrical signal has a pulse duration of 0.005-0.1 ms, such that the electrical signal to the vagal nerve produces an improvement in a physiological parameter indicative of treating bronchoconstriction in the patient,
providing a detector for detecting the physiological parameter; and
measuring the physiological parameter, wherein the physiological parameter is airway smooth muscle (ASM) tone, blood oxygen saturation, blood carbon dioxide concentration, tidal mid-expiratory flow, respiratory rate, total lung capacity, or forced expiration volume;
wherein the improvement in the physiological parameter is a decrease in airway smooth muscle tone, an increase in blood oxygen saturation, a decrease in blood carbon dioxide concentration, an increase in tidal mid-expiratory flow, a decrease in respiratory rate, an increase in total lung capacity, or an increase in forced expiration volume, from an initial measurement.