Patent ID: 11857622
Assignee: PFIZER INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 22:
23. The mutant according to claim 7, wherein the amino acid mutations are a combination of mutations selected from the group consisting of:
(1) combination of D217C and Y589C, M371C and W506C, and 1675S;
(2) combination of D217C and Y589C, N524C and M684C, and 1675S;
(3) combination of D217C and Y589C, M371C and W506C, Y155G 1156H H157R, W240A, C246S and 1675S; and
(4) combination of D217C and Y589C, N524C and M684C, Y155G 1156H H157R, W240A, C246S and 1675S.