Patent ID: 11866496
Assignee: GENENTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 7:
8. The immunoconjugate of claim 7, wherein the immunoconjugate comprises Formula I:

Ab-(L-D)p  I

wherein:
(a) Ab is the anti-CD79b antibody,
(b) L is a linker,
(c) D is the drug moiety, wherein the drug moiety is selected from the group consisting of an auristatin, a dolastatin, and a maytansinoid,
(d) p ranges from about 1 to about 8; and
wherein the anti-CD79b antibody is attached through the one or more engineered cysteines to the drug moiety (D) by the linker (L).