Patent ID: 11918610
Assignee: GEORGY VIKTOROVICH TETS
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G  Y | IPC A  C

Claim 7:
8. The method of claim 1, wherein the method comprises:
a)(i) determining the level of said amyloid-producing E. coli bacteria in gastrointestinal microbiota of the mammal at an earlier time point followed by (ii) determining the level of said amyloid-producing E. coli bacteria in gastrointestinal microbiota of the mammal at a later time point,
b) comparing the levels determined in steps (a)(i) and (a)(ii) to each other and to corresponding control levels in mammals from an age-matched and/or gender-matched reference population, and
c) determining that the mammal is susceptible to T1D, when the level of said amyloid-producing E. coli bacteria in gastrointestinal microbiota of the mammal is increased at the earlier time point followed by a substantial depletion in the level or the total disappearance of said amyloid-producing E. coli bacteria in gastrointestinal microbiota of the mammal at the later time point.