Patent ID: 11912795
Assignee: TISSUE REPAIR LTD
Field: Macromolecular chemistry, polymers (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. An isolated biological polysaccharide compound comprising:
glycosyl linkages comprising 1:3 linked glucopyranosyl residue of 65-95% wt. of the isolated biological polysaccharide compound and 1:6 linked glucopyranosyl residue of 5-25% wt. of the isolated biological polysaccharide compound;
a purity of 85-100% β-D-glucan;
a molecular weight of 0.5 to 2.2 MDa;
a TNF-alpha cytokine response in a human bioassay that is at least 1.5 times greater than a negative control TNF-alpha cytokine response in the human bioassay; and,
additional side chains comprising
1:4 linked glucopyranosyl residue 2-6% wt. of the isolated biological polysaccharide compound;
3:4 linked glucopyranosyl residue 0.01-0.5% wt. of the isolated biological polysaccharide compound;
2:3 linked glucopyranosyl residue 0.5-4% wt. of the isolated biological polysaccharide compound;
3:6 linked glucopyranosyl residue 3-10% wt. of the isolated biological polysaccharide compound;
2:6 and 4:6 linked glucopyranosyl residue 0.2-1% wt. of the isolated biological polysaccharide compound;
3:4:6 linked glucopyranosyl residue 0.01-0.5% wt. of the isolated biological polysaccharide compound; and
terminal linked glucopyranosyl residue 2-8% wt. of the isolated biological polysaccharide compound; and

wherein said isolated biological polysaccharide compound is insoluble in aqueous solutions.