Patent ID: 11872279
Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 3:
4. The SARS-CoV-2 S glycoprotein variant of claim 3, wherein
(a) the at least one amino acid residue is selected from: L122, L125, F126, Y159, F160, and any combination thereof;
(b) the S glycoprotein variant comprises an amino acid substitution at L122 with a different amino acid residue;
(c) the S glycoprotein variant comprises an amino acid substitution at L122 and F160 with a different amino acid residue; or
(d) the S glycoprotein variant comprises an amino acid substitution at L122, L125, F126 and F160 with a different amino acid residue.