Patent ID: 11929149
Assignee: ARC BIO, LLC
Field: Computer technology (Electrical engineering)
Classification: CPC G  C | IPC C  G

Claim 12:
13. The method of claim 10, wherein abnormal alignment comprises one or more of the following:
a) an aligned read pair orientation different from that of a majority of aligned read pairs;
b) an aligned read pair insert length that is smaller or larger than that of a majority of aligned read pairs;
c) a read pair in which one read is aligned and one read is unaligned;
d) a read in which a part of the read is clipped;
e) a read pair in which an insert length is larger than the 99th percentile or smaller than the 1st percentile of insert lengths of a subset of aligned read pairs; and
f) a read pair in which reads align to different reference sequences.