Patent ID: 11964944
Assignee: UNIVERSITY OF LEEDS
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The compound of claim 1, having the structure of (I):, or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof,
wherein
ring A combines with Y1 and Y2 to form a C3-7cycloalkenyl or heteroaryl ring,
wherein the C3-7cycloalkenyl or heteroaryl is optionally substituted by halogen, C1-3alkyl, C1-3alkoxy, C1-3haloalkyl, —O—C1-3haloalkyl, —S—C1-3haloalkyl, —C(O)OR, cyano or phenyl;

Y1 is N;
Y2 is C or N;
X1 is C(Rx1) or N,
wherein Rx1 is hydrogen, halogen, C1-3alkyl, C1-3alkoxy or C1-3haloalkyl;

X2 is C(Rx2) or N,
wherein Rx2 is hydrogen, halogen, C1-3alkyl, C1-3alkoxy or C1-3haloalkyl;

X3 is O, N(R), S or C1-3alkyl;
X4 is C or N;
X5 is C or N;
R1 is hydrogen or C1-3alkyl;
R2 is hydrogen, C1-3alkyl, C1-3haloalkyl, —CH2OH, —CH2OR or —C(O)OR;
n is 0, 1, 2, 3 or 4;
each R3 is independently halogen, C1-3alkyl, C1-3alkoxy, C1-3haloalkyl, —O—C1-3haloalkyl, —S—C1-3haloalkyl, —C(O)OR or SF5;
or two R3 groups, together with the carbons to which they are attached, form a 1,3-dioxolane; and
each R is independently hydrogen or C1-3alkyl.