Patent ID: 11967435
Assignee: UCL BUSINESS LTD
Field: Medical technology (Instruments)
Classification: CPC G  A | IPC A  G

Claim 10:
11. A system comprising:
a non-transitory computer readable medium storing instructions; and
a processor configured to access the non-transitory computer readable medium and execute the instructions to at least:
receive at least one imaging data set of a portion of a patient's anatomy and at least one physiological data set related to clinical measurements of the patient;
execute a two dimensional model of circulation in a large spatial region of the patient's body comprising at least an aorta and a left ventricle based on the at least one imaging data set related to the patient and the at least one physiological data set related to the patient, wherein the two dimensional model of circulation uses an electrical circuit analogy;
output estimations of flow and pressure in the aorta and the left ventricle of the patient for a plurality of varied left ventricular assist device (LVAD) operating parameters to evaluate performance of the LVAD in terms of potential impact on the patient's physiology;
execute a three dimensional model of at least one component of the large spatial region of the patient's body and at least one component of the LVAD within the at least one component of the large spatial region based on the output estimations of flow and pressure from the two dimensional model, the at least one imaging data set of the portion of the patient's anatomy, and the at least one physiological data set related to the clinical measurements of the patient;
output a plurality of flow patterns from the three-dimensional model of the at least one component of the large spatial region of the patient's body and the at least one component of the LVAD within the at least one component of the large spatial region that are calculated by computational fluid dynamic calculations using the plurality of varied LVAD operating parameters, varied LVAD component parameters, and varied pulsatile flow conditions;
determine an ideal parameter related to the LVAD by comparing the plurality of flow patterns for optimal circulatory function of the patient; and
output to an output device, by the system, the ideal parameter and an optimal LVAD position and/or an optimal LVAD setting for the optimal circulatory functioning of the patient based on the ideal parameter.