Patent ID: 11951113
Assignee: NEURALIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A combination composition comprising as active components:
a steroidal saponin of natural or synthetic origin, a pharmaceutical acceptable salt thereof, at a concentration of 0.03 pM to 0.3 pM;
caffeic acid as first polyphenolic compound at a concentration of 5 nM to 50 nM; and
ferulic acid as second polyphenolic compound at a concentration of 1 nM to 10 nM,
wherein the active components of the combination composition consist of the steroidal saponin of natural or synthetic origin, a pharmaceutical acceptable salt thereof, caffeic acid and ferulic acid,
wherein the steroidal saponin is selected from the group consisting of diosgenin, dioscin, protodioscin, sarsasapogenin, sarsaponin, smilagenin, tigogenin, laxogenin, and mixtures thereof, and
wherein said concentration of 0.03 pM to 0.3 pM of steroidal saponin is an effective concentration less than an effective concentration of steroidal saponin required without caffeic acid at said concentration of 5 nM to 50 nM and/or ferulic acid at said concentration of 1 nM to 10 nM.