Patent ID: 11918635
Assignee: SHENZHEN NEOCURNA BIOTECHNOLOGY CORPORATION
Field: Measurement (Instruments)
Classification: CPC G  A  Y | IPC A  G

Claim 0:
1. A system for detecting an immunogenicity of a tumor neoantigen, comprising the following components:
(1) a Roswell Park Memorial Institute (RPMI) medium comprising 10% (v/v) heat inactivated human serum AB, 100 U/ml penicillin, 100 U/ml streptomycin, 1 mM sodium pyruvate, 0.1 mM non-essential amino acids, 10 mM 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (HEPES), 2.5 μg/ml amphotericin B, and 0.05 mM 2-mercaptoethanol;
(2) cytokines;
(3) polyinosinic-polycytidylic acid (Poly I:C);
(4) an antigenic peptide fragment of a human influenza; and
(5) an enzyme-linked immunospot (ELISPOT) Reader.