Patent ID: 11971413
Assignee: BOE TECHNOLOGY GROUP CO., LTD.
Field: Measurement (Instruments)
Classification: CPC G  A  C  Y | IPC A  C  G

Claim 11:
12. A method for preparing the peptoid according to claim 1, comprising:
(1) carrying out an amidation reaction between a compound of Formula II and an amino group at a terminal end of a solid phase support resin to form an amide bond;, wherein R is OH or Cl;
(2) adding a monomer to replace the bromine atom through a nucleophilic substitution reaction;
(3) repeating steps (1) and (2) until the synthesis of all subunits is completed,
wherein the monomers are added in an order of cysteine, monoprotected tetramethylenediamine, monoprotected tetramethylenediamine, β-alanine, ethanolamine, monoprotected tetramethylenediamine, and isobutylamine, wherein the wording “monoprotected” means that one amino group in the diamine is protected by an amino protecting group; and
(4) removing the amino protecting group on the side chain, and cleaving the peptoid from the resin.