Patent ID: 11942187
Assignee: LIPOSCIENCE, INC.
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method of determining a subject's risk of having and/or developing CHD, comprising:
obtaining a composite Nuclear Magnetic Resonance (NMR) spectrum of a biosample comprising blood, plasma, or serum of a subject;
deconvolving the composite NMR spectrum to obtain concentration measurement values of small and large HDL subclass particles in the biosample;
programmatically adjusting at least one of the NMR-derived small and large HDL subclass particle concentration measurement values based on a predetermined mathematical model, wherein the model comprises at least one weighting factor;
using the adjusted HDL subclass particle concentration measurement values to generate a CHD risk value; and
determining the subject's risk of having and/or developing CHD based on the generated CHD risk value.