Patent ID: 11926676
Assignee: CRISPR THERAPEUTICS AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 11:
12. The masked CAR of claim 1, wherein the scFv that binds PTK7 comprises a heavy chain variable domain (VH), which comprises a VH CDR1 sequence of SEQ ID NO: 23, a VH CDR2 sequence of SEQ ID NO: 24, and a VH CDR3 sequence of SEQ ID NO: 25; and/or wherein the anti-PTK7 antibody comprises a light chain variable domain (VL), which comprises a VL CDR1 sequence of SEQ ID NO: 26, a VL CDR2 sequence of SEQ ID NO: 27 and a VL CDR3 sequence of SEQ ID NO: 28.