Patent ID: 11932704
Assignee: SANOFI
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The method of claim 1, wherein the CL domain of the first polypeptide chain is a human kappa CL domain, and the CL domain of the fourth polypeptide chain is a human lambda CL domain; or the CL domain of the first polypeptide chain is a human lambda CL domain, and the CL domain of the fourth polypeptide chain is a human kappa CL domain, and the method further comprises:
(d) contacting the binding protein eluted in (c) with a kappa light chain affinity medium; and
(e) eluting the binding protein from the kappa light chain affinity medium under conditions suitable for isolating the binding protein away from binding proteins comprising only lambda CL domains.