Patent ID: 11939345
Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. A process for performing fluorescence probing with a physiologically stable fluorophore, , the process comprising: contacting a surface extracted cellulose nanofiber substrate with the physiologically stable fluorophore; forming a fluorophore-substrate complex from the physiologically stable fluorophore and the substrate in response to contacting the substrate with the physiologically stable fluorophore; subjecting the fluorophore-substrate complex to probe radiation; electronically exciting the physiologically stable fluorophore in the fluorophore-substrate complex in response to subjecting the fluorophore-substrate complex to the probe radiation; producing fluorescence from the physiologically stable fluorophore in the fluorophore-substrate complex in response to electronically exciting the physiologically stable fluorophore in the fluorophore-substrate complex; and determining, from the fluorescence from the physiologically stable fluorophore, the redox state of the substrate to perform single-electron transfer fluorescence probing; wherein the physiologically stable fluorophore is stable from pH=1 to pH=10 such that the photophysics of the physiologically stable fluorophore is conserved from pH=2 to pH=10.