Patent ID: 11882823
Assignee: nan
Field: Basic materials chemistry (Chemistry)
Classification: CPC A | IPC A

Claim 4:
5. A method for stabilizing and analyzing a biological specimen post-draw, the method comprising:
contacting a biological specimen having cells of hematopoietic or non-hematopoietic origin and of a volume sufficient to conduct flow cytometry with a stabilizing composition, the stabilizing composition comprising:
a heavy metal salt,
saccharide having a concentration in the stabilizing composition from 1.5 to 3.0 Molar,
an aliphatic aldehyde having a concentration in the stabilizing composition from 0.001 to 0.15 Molar,
a pH from 5.9 to 8.0, and
a solvent;

storing the biological specimen contacted with the stabilizing composition at a temperature from minus 20 degrees Celsius to minus 200 degrees Celsius for at least 1 day to stabilize the biological specimen;
thawing the biological specimen contacted with the stabilizing composition;
staining the biological specimen contacted with the stabilizing composition;
lysing red blood cells in the biological specimen contacted with the stabilizing composition;
analyzing the biological specimen to determine the presence or absence of a condition of interest.