Patent ID: 11967399
Assignee: SHENZHEN NEOCURA BIOTECHNOLOGY CORPORATION
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C  G

Claim 2:
3. The method according to claim 1, wherein, step S2: annotating and filtering the somatic mutations to obtain filtered somatic mutations, and translating the filtered somatic mutations to obtain the mutant peptide sequences of the patient, comprises:
step S201: annotating and filtering the somatic mutations, comprising removing synonymous mutations and intronic mutations, to obtain the filtered somatic mutations;
step S202: performing a protein translation on the filtered somatic mutations to obtain a mutant proteome of the patient; and
step S203: applying sliding windows to the mutant proteome of the patient with a predetermined length to obtain candidate antigen peptides of the patient, wherein the candidate antigen peptides contain mutation sites, wherein the candidate antigen peptides are the mutant peptide sequences.