Patent ID: 11857634
Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A formulation, comprising: a plurality of polymers comprising a hydrophobic polymer backbone formed via radical polymerization, a first plurality of pendant groups attached to the hydrophobic polymer backbone and comprising at least one cationic group, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and comprising at least one hydrophilic polymer, wherein the first plurality of pendant groups is attached to the hydrophobic polymer backbone via a first linking group comprising at least a first aromatic group which is interactive via π-π stacking and the second plurality of pendant groups is attached to the hydrophobic polymer backbone via a second linking group comprising at least a second aromatic group which is interactive via π-π stacking,
a first therapeutic compound, and
a second therapeutic compound, wherein the second therapeutic compound is different from the first therapeutic compound and comprises a nucleic acid.