Patent ID: 11951240
Assignee: GAMBRO LUNDIA AB
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 8:
9. The CRRT apparatus of the previous claim 7, wherein the control unit is configured to calculate the steady state acid-base balance parameter in the blood of the patient as follows:, nNBL
  =
  
   
    
     J
     
      buffer
      ⁢
      _
      ⁢
      load
     
    
    BW
   
   =
   
    
     
      J
      
       met
       ⁢
       _
       ⁢
       cit
      
     
     +
     
      J
      
       HCO
       ⁢
       3
       ⁢
       
        _
        ⁢
        bal
       
      
     
     -
     
      J
      
       H
       +
      
     
    
    BW, alternatively, when also lactate balance is considered, the control unit is configured to calculate the steady state acid-base balance parameter in the blood of the patient as follows:, nNBL
  =
  
   
    
     
      
       J
       
        buffer
        ⁢
        _
        ⁢
        load
       
      
     
    
    
     
      BW
     
    
   
   =
   
    
     
      
       
        J
        
         met
         ⁢
         _
         ⁢
         cit
        
       
       +
       
        J
        
         HCO
         ⁢
         3
         ⁢
         
          _
          ⁢
          bal
         
        
       
       +
       
        J
        
         met
         ⁢
         _
         ⁢
         lact
        
       
       -
       
        J
        
         H
         +
        
       
      
     
    
    
     
      BW, wherein:
nNBL is the steady state acid-base balance parameter,
Jbuffer_load is a mass transfer rate of a net buffer during extracorporeal therapy,
Jmet_cit is a mass transfer rate of bicarbonate generated from the metabolism of citrate infused to the patient,
JHCO3bal is a mass transfer rate of bicarbonate balance during extracorporeal therapy,
Jmet_lact is a mass transfer rate of lactate infused to the patient,
JH+ is a mass transfer rate of acid infusion, and
BW is a body weight of the patient.