Patent ID: 11944690
Assignee: BAYER AKTIENGESELLSCHAFT
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 9:
10. The process according to claim 9, further comprising one or more additional steps selected from the group consisting of:
dissolving a buffer in the pharmaceutically acceptable solvent or the solution, thereby obtaining a buffered solution and adjusting the pH of the buffered solution to a pH in a range of 7.6 to 8.2 (inclusive);
dissolving the Ca-BT-DO3A (Calcobutrol) in the solution;
dissolving an isotonicity agent in the solution;
adjusting the pH of the solution to a pH in a range of 4.5 to 8.5 (inclusive);
adjusting the concentration of the DO3A-derived tetra-chelate of the formula (I) by addition of an additional amount of the pharmaceutically acceptable solvent; and
sterilizing the solution.