Patent ID: 11865216
Assignee: ARON H. BLAESI
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A

Claim 36:
37. A pharmaceutical dosage form comprising:
a drug-containing solid having an outer surface and an internal three dimensional structural framework comprising a plurality of criss-crossed stacked layers of fibrous structural elements with average fiber thickness in the range of 2.5 μm to 2 mm, said framework contiguous with and terminating at said outer surface;
said fibrous structural elements comprising at least an active pharmaceutical ingredient, at least an absorptive polymeric excipient being mutually soluble with a physiological fluid, and at least a hydrophilic surface composition;
said fibrous structural elements further having segments spaced apart from like segments of adjoining fibrous elements, thereby defining free spaces, wherein a plurality of adjacent free spaces of successive layers combine to define one or more interconnected free spaces forming an open pore network;
wherein
upon immersion in a physiological fluid said open pore network enables uniform wetting of the structural framework, and the physiological fluid penetrates into the thin fibers, so that the drug-containing solid expands in all dimensions and transitions to a viscous medium.