Patent ID: 11963994
Assignee: GENENTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of treating a patient suffering from a cancer that has failed to undergo apoptosis, the method comprising:
administering a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein:
Ph is phenyl;
R1 is C3-7 cycloalkyl; and
R2, R3, R4, R5, and R6 are each independently H or C1-6 alkyl;
and
administering one or more agents that modulate:
a protein kinase selected from the group consisting of serine/threonine specific kinases, receptor tyrosine specific kinases, and non-receptor tyrosine specific kinases,
or a non-kinase target selected from the group consisting of histone deacetylases, DNA methyltransferases, heat shock proteins, hedgehog inhibitors, and proteosomes.