Patent ID: 11972568
Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
Field: Medical technology (Instruments)
Classification: CPC G  A | IPC A  G

Claim 19:
20. A computer-readable storage medium comprising processor-executable instructions that, when executed by at least one processor of a computing device, cause the computing device to:
receive a spectral-domain optical coherence tomography (SD-OCT) image;
determine a thickness of a macular ganglion cell layer (GCL) within at least one of one or more regions of interest of the SD-OCT image;
determine, for at least one of the one or more regions of interest, a set of correlations of the GCL thickness to each of a plurality of optic nerve head (ONH) regions;
select from the plurality of ONH regions, based on a highest correlation from among the set of correlations, an ONH region indicative of macular damage;
determine, for each of a plurality of nerve fiber bundle (NFB) regions within at least one of the one or more regions of interest, a connectivity path of the GCL to at least two nerve fiber bundle (NFB) segments within the NFB region; and
determine, for each NFB region, a path of a retinal ganglion cell-axonal complex (RGC-AC) segment with a highest cumulative correlation among all possible RGC-AC segment paths.