Patent ID: 11965190
Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 4:
5. A vector comprising a coding region and a heterologous promoter operably linked to the coding region that encodes an antimicrobial peptide,
wherein the heterologous promoter comprises a chloride-inducible promoter,
wherein the antimicrobial peptide comprises a catalytic domain of Lys2ConCat (SEQ ID NO:3) or Lys2Con20Cat (SEQ ID NO:4),
wherein the coding region encoding the antimicrobial peptide is operably linked to a coding region encoding a signal peptide, and
wherein the vector comprises an additional coding region that is operably linked to a second promoter, and further wherein the additional coding region encodes a modulator protein
that regulates the expression of the coding region encoding the antimicrobial peptide and is
operably linked to the heterologous promoter.