Patent ID: 11938418
Assignee: CYTIVA SWEDEN AB
Field: Chemical engineering (Chemistry)
Classification: CPC B  G | IPC B  G

Claim 8:
9. A method for controlling a periodic counter current chromatography system comprising at least two columns, comprising the steps of:
measuring a first pressure representative of the unloaded column from each column in the system;
measuring a second pressure representative of the loaded column from each column in the system;
determining the saturation level of each chromatography column according to claim 5; and
determining whether the level of saturation has reached a saturation point level, and, if the saturation point level is reached, modifying a flow rate of (i) a buffer pump or (ii) the feed to and between the columns in dependence of the determined saturation level, wherein the level of saturation is continuously monitored during a chromatography process by measuring the second pressure continuously.