Patent ID: 11898180
Assignee: AVALON POLYTOM (HK) LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC C

Claim 0:
1. A method of selectively inhibiting a cancer cell having low asparaginase expression, comprising:
introducing an arginase to a media in contact with the cancer cell to reduce arginine concentration in the media to a concentration effective to inhibit growth of the cancer cell; and
introducing an asparaginase to the media to reduce asparagine concentration in the media to a concentration effective to inhibit growth of the cancer cell,
wherein the arginase and the asparaginase in combination provide a synergistic effect in reducing viability of the cancer cell, wherein the synergistic effect exceeds additive effects of monotherapies with the arginase and the asparaginase in inhibition of growth of the cancer cell having low asparaginase expression.