Patent ID: 11891418
Assignee: BISY E.U.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A methylotrophic Komagataella yeast comprising an orthologous promoter obtained from a Hansenula yeast cell or a variant of the orthologous promoter, inducible by derepression,
wherein the orthologous promoter is an orthologous formate dehydrogenase (FMD) promoter comprising the nucleic acid sequence of SEQ ID NO: 1, and
wherein the variant of the orthologous promoter comprises a nucleic acid sequence selected from the group consisting of SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, SEQ ID NO: 41, SEQ ID NO: 42, SEQ ID NO: 43, SEQ ID NO: 44, SEQ ID NO: 45, SEQ ID NO: 46, SEQ ID NO: 47, SEQ ID NO: 48, SEQ ID NO: 49, SEQ ID NO: 50, SEQ ID NO: 51, SEQ ID NO: 52, SEQ ID NO: 53, SEQ ID NO: 54, SEQ ID NO: 55 and SEQ ID NO: 56.