Patent ID: 11918611
Assignee: CRIGASSENI AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 11:
12. A method for the prophylaxis and/or treatment of a Clostridium difficile infection in a patient in need of such treatment or prophylaxis, comprising the steps of:
administering an effective amount of a peptidoglycan hydrolase (PGH)-secreting probiotic bacterial strain that includes Lactobacillus gasseri CCOS 960 (DSM 32296), Lactobacillus plantarum CCOS 893 (DSM 32352), Lactobacillus johnsonii CCOS 824 (CCOS 824), Lactobacillus paracasei subsp. Paracasei CCOS 1205 (CCOS 1205), Lactobacillus paracasei subsp. Paracasei CCOS 1201 (CCOS 1201), or Lactobacillus rhamnosus CCOS 965 (CCOS 965),
wherein the peptidoglycan hydrolase (PGH) is alpha-N-acetylglucosaminidase, beta-N-acetylglucosaminidase, or a combination thereof, and the method effectuates the prophylaxis and/or treatment of a Clostridium difficile infection in the patient.