Patent ID: 11857522
Assignee: BEYONDSPRING PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A pharmaceutical composition, comprising a compound of Formula (I):, Y1 is selected from hydroxyl, C1-4 alkylamino and acylamino having a C1-4 alkyl moiety thereof;
Y2, Y3 and Y4 are independently selected from hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, trifluoromethyl, hydroxyl and benzyloxy; and
Q1 is either, , where Q2 and Q3 are independently selected from hydrogen and C1-4 alkyl;
X is selected from cyano, carboxyl or a derivative thereof, 5-tetrazolyl and alkylsulfonylcarbamyl having a C1-6 alkyl moiety thereof; and
n is 0 or an integer selected from 1, 2, 3, 4, 5 and 6, and a pharmaceutically acceptable salt thereof; and
one or more immune checkpoint inhibitor,
wherein the one or more immune checkpoint inhibitor is an inhibitor of PD-1, PD-L1, PD-L2, or CTLA-4.