Patent ID: 11857958
Assignee: UNIVERSITE GRENOBLE ALPES
Field: Biotechnology (Chemistry)
Classification: CPC B  C | IPC B  C

Claim 0:
1. A microfluidic cell culture chip comprising a central module that comprises:
a central unit, which contains
a support consisting of a non-resorbable membrane, said support comprising an upper face and a lower face and being perforated by at least one perforation,
a 3D nanostructured porous membrane, juxtaposed to the non-resorbable membrane, comprising an upper face and a lower face, and comprising at least one protuberance, said at least one protuberance being hollow, comprising an outer face and an inner face and forming a relief structure on a side of the upper face of the 3D nanostructured porous membrane,

said lower face of said 3D nanostructured porous membrane being positioned and secured to said upper face of said support, or said upper face of the 3D nanostructured porous membrane being positioned and secured to said lower face of said support, and
said 3D nanostructured porous membrane and the at least one protuberance being composed of materials, suitable for a culture of two distinct cell types; and
a base,
said central unit being integrated in said base and forming a whole with said base.