Patent ID: 11918590
Assignee: INTAS PHARMACEUTICALS LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 4:
5. A stable extended release pharmaceutical composition comprising Clozapine with one or more pharmaceutically acceptable excipients, wherein the said composition provides dissolution profile as: (1) not more than 30% weight of Clozapine is dissolved in 30 minutes; (2) between 40% to 70% weight of Clozapine is dissolved in 2 hours; and (3) more than 80% weight of Clozapine is dissolved in 10 hours, wherein the dissolution profile is measured using a USP type I apparatus (basket), placing the composition in 900 ml of acetate buffer having pH 4.5 at 37° C. and 100 rpm.