Patent ID: 11945872
Assignee: REGENERON PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 11:
12. An antibody or antigen-binding fragment thereof that binds to ACVR1, wherein the antibody or antigen-binding fragment comprises
three heavy chain CDRs (HCDR1, HCDR2 and HCDR3) contained within a HCVR comprising the amino acid sequence of SEQ ID NO: 42, and three light chain CDRs (LCDR1, LCDR2 and LCDR3) contained within a LCVR comprising the amino acid sequence of SEQ ID NO: 48; or
three heavy chain CDRs (HCDR1, HCDR2 and HCDR3) contained within a HCVR comprising the amino acid sequence of SEQ ID NO: 58; and three light chain CDRs (LCDR1, LCDR2 and LCDR3) contained within a LCVR comprising the amino acid sequence of SEQ ID NO: 62.