Patent ID: 11911353
Assignee: JIANGNAN UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of use of a compound, comprising preparing medicines for inhibiting fatty acid synthase using the compound, wherein the structure of the compound is the general formula (I) or pharmaceutically acceptable salts thereof;, wherein,  is a single bond or a double bond; R1 is independently selected from any one of hydroxyl, halogen, C1-C4 alkyl and C1-C4 alkoxy;
ring A is, , and U, V and Z are each independently selected from CH, N and NH; R3 and R4 are each independently selected from any one of hydrogen, halogen, hydroxyl, aryloxy and alkoxy, and R3 and R4 are not hydrogen at the same time;
Q is at least one heteroatom or C1-5 straight or branched-chain hydrocarbyl containing no heteroatoms, and the heteroatoms are independently selected from nitrogen, oxygen and sulfur;
L is keto or imino;
W is selected from any one of —(CH2)a, —(CH2)a—C(O)—, —(CH2)a—OC(O)— and —(CH2)n—C(O)O—,
wherein a is a natural number of 0-3; and
X is selected from —N(R)mN(R)n—, —C(O)N(R)n— or —N(R)nC(O)—, and m and n are each independently 0 or 1; R is independently hydrogen, halogen or phenyl; and Y is selected from nitrogen, oxygen or sulfur.