Patent ID: 11890394
Assignee: INSTRUCTURE LABS B.V.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A medical implant adapted for placement inside of or on a body surface of a subject, the medical implant comprising:
a textured surface which, in use, directly contacts one or more of biological fluid, tissue, and cells of the subject, the textured surface having an arithmetical mean height value (Sa) below 3.0 μm, a developed interfacial area ratio (Sdr) above 1.0, and a density of peaks (Spd) above 1×106 peaks/mm2, wherein the Sa, the Sdr, and the Spd are measured according to ISO 25178 using a Gaussian low pass S-filter with a nesting index value of at least 0.25 μm, and
whereby the contact effects one or more of: limiting fibrosis, limiting foreign body response, resisting bacterial and viral adhesion and proliferation, resisting blood coagulation and thrombosis, promoting biological adhesion and integration of biological tissue, guiding cell differentiation, instructing cell migration, promoting cell survival, and perpetuating a selected cellular phenotype limiting fibrosis, with respect to the medical implant.