Patent ID: 11963796
Assignee: BIOLINQ INCORPORATED
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 18:
19. A method for quantifying a physiological or biochemical entity in a physiological fluid or tissue, the method comprising:
providing a die stack mounted on a printed circuit board, the die stack comprising:
a first substrate comprising:
an anterior surface comprising an array of microneedles configured to sense an electrophysiological or electrochemical reaction within physiological fluid or tissue; and
a first conductive conduit in electrical communication with a first microneedle of the array of microneedles and extending through the first substrate; and

a second substrate comprising:
a second conductive conduit extending through the second substrate and longitudinally aligned with the first conductive conduit,
wherein the first conductive conduit and the second conductive conduit are configured to provide electrical communication between the first microneedle of the array of microneedles and the printed circuit board, and
wherein a posterior surface of the second substrate comprises a CMOS circuitry transducer;

penetrating a biological interface with the array of microneedles;
routing a signal produced by an electrophysiological or electrochemical reaction within the physiological fluid or tissue from a first microneedle of the array of microneedles to a printed circuit board via the first conductive conduit, the CMOS circuitry transducer, and the second conductive conduit; and
interpreting the signal with the printed circuit board to determine a level of the physiological or biochemical entity.