Patent ID: 11967430
Assignee: OPTUM SERVICES (IRELAND) LIMITED
Field: Computer technology (Electrical engineering)
Classification: CPC G | IPC G

Claim 9:
10. The computer-implemented method of claim 6, wherein determining the pairwise polygenic similarity measure for a particular object pair comprises:
identifying a plurality of genetic variants each associated with at least one of the primary cross-variant polygenic risk data object in the particular object pair and the secondary cross-variant polygenic risk data object in the particular object pair;
selecting a comparative variant subset of the plurality of genetic variants;
for each genetic variant in the comparative variant subset, determining a per-variant pairwise polygenic similarity measure based at least in part on comparing a primary per-variant genetic risk score for the genetic variant inferred from the primary cross-variant polygenic risk data object and a secondary per-variant genetic risk score for the genetic variant inferred from the secondary cross-variant polygenic risk data object; and
determining the pairwise polygenic similarity measure based at least in part on each per-variant pairwise polygenic similarity measure for a genetic variant in the comparative variant subset.