Patent ID: 11965183
Assignee: OXFORD NANOPORE TECHNOLOGIES PLC
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 19:
20. The method of claim 19, wherein the substitutions correspond to: F98W/K194L/H64N, F98W/K194L/H64Q, F98W/K194L/H64K, F98W/K194L/H64F, F98W/K194L/T80K, F98W/K194L/T80Q, F98W/K194L/T80N, F98W/K194L/H82N, F98W/K194L/H82Q, F98W/K194L/H82W, F98W/S83H/K194L, F98W/S83T/K194L, F98W/S83R/K194L, F98W/S83Q/K194L, F98W/S83N/K194L, F98W/S83K/K194L, F98W/N88R/K194L, F98W/N88H/K194L, F98W/N88W/K194L, F98W/N88Y/K194L, F98W/S83H/K194L/F276K, F98W/P89L/K194L, F98W/P89V/K194L, F98W/P89I/K194L, F98W/P89T/K194L, F98W/D121H/K194L, F98W/D121Y/K194L or F98W/D121K/K194L, F98W/V150I/K194L, F98W/V150L/K194L, F98W/V150N/K194L, F98W/V150W/K194L, F98W/V150H/K194L, F98W/P152W/K194L, F98W/P152F/K194L, F98W/P152Y/K194L, F98W/P152H/K194L, F98W/P152I/K194L, F98W/P152L/K194L, F98W/P152V/K194L, F98W/F240W/K194L, F98W/F240Y/K194L, F98W/F240H/K194L, F98W/N242H/K194L, F98W/N242Q/K194L, F98W/K194L/F276K, F98W/K194L/F276H, F98W/K194L/F276W, F98W/K194L/F276R, F98W/K194L/S287K, F98W/K194L/S287R, F98W/K194L/S287W, F98W/K194L/S287F, F98W/N293Q/K194L, F98W/N293K/K194L, F98W/N293H/K194L, F98W/T394K/K194L, F98W/T394H/K194L, F98W/T394N/K194L, F98W/H396Y/K194L, F98W/H396F/K194L, F98W/H396Q/K194L, F98W/H396K/K194L, F98W/K397R/K194L, F98W/K397H/K194L, F98W/K397Y/K194L, F98W/Y415W/K194L, or F98W/Y415R/K194L in SEQ ID NO: 8.