Patent ID: 11970688
Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
Field: Measurement (Instruments)
Classification: CPC B  C  G | IPC C  G

Claim 0:
1. A cell monitoring apparatus, comprising:
a sensing chip, comprising:
a channel region comprising a first semiconductor material;
a pair of source and drain regions disposed at opposite sides of the channel region and comprising a second semiconductor material; and
a sensing film disposed on the channel region at a sensing surface of the sensing chip; and

a channel module, disposed on the sensing surface of the sensing chip, and has a proximal surface facing the sensing surface of the sensing chip and a distal surface opposite to the proximal surface,
wherein a microfluidic channel is disposed between the sensing surface of the sensing chip and the proximal surface of the channel module, the microfluidic channel comprising:
a culture chamber, concave into the proximal surface of the channel module, wherein the culture chamber comprises a bottom surface, a first level height of the bottom surface is between a second level height of the proximal surface and a third level height of the distal surface; and
a micro-well, concave into the bottom surface of the culture chamber, wherein the micro-well is located at a level height between the first level height and the third level height.