Patent ID: 11945838
Assignee: INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 3:
4. A process for synthesis of the site-modified protein/peptide amphiphile of claim 1, comprising:
i. functionalizing the oligoethylene glycol hydrophilic spacer group with 2-pyridine carboxaldehyde to obtain a functionalized active amphiphilic probe (AAP), and
ii. reacting a protein or peptide with 50 to 100 equivalents of the functionalized active amphiphilic probe (AAP) of step (i) to obtain a conjugated protein or peptide with a modified N-terminal amino acid; and
iii. self-assembling the conjugated protein or peptide through micelle assisted protein labelling to yield the site-modified protein/peptide amphiphile.