Patent ID: 11906518
Assignee: X DEVELOPMENT LLC
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 0:
1. A method comprising:
assaying a sample of tumor cells using a microfluidic device, wherein the assaying comprises:
randomly affixing the tumor cells to a surface of the microfluidic device; and
flowing a plurality of aptamers over the tumor cells to allow the aptamers to interact and bind to the tumor cells,

wherein:
the tumor cells comprise one or more unknown subtypes of the tumor cells,
the plurality of aptamers comprises a plurality of aptamer families, and
each aptamer family of the plurality of aptamer families is determined by a prediction model to bind to at least one possible subtype of the tumor cells;

obtaining data from assaying the sample of tumor cells, wherein
the data comprises a measure of binding affinity of each aptamer family to the tumor cells;

analyzing the measure of the binding affinity of each aptamer family to the tumor cells, wherein the analyzing comprises classifying the binding affinity of each aptamer family to the tumor cells; and
determining one or more aptamer families that characterize the one or more unknown subtypes of the tumor cells based on the classifying.