Patent ID: 11964027
Assignee: nan
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of transducing a population of cells comprising the steps of:
(a) contacting the population of cells with cyclosporin H (CsH); and
(b) transducing the population of cells with a viral vector, wherein the viral vector is a lentiviral or gamma-retroviral vector and wherein the viral vector is pseudotyped to enter cells via an endocytosis-dependent mechanism,, wherein the population of cells comprises: (i) CD34+ HSPCs; (ii) CD14+ monocytes; (iii) CD4+ or CD3+ T cells; (iv) CD34+ bone marrow cells; or (v) CD34+ peripheral blood cells.