Patent ID: 11942313
Assignee: SHIMADZU CORPORATION
Field: Measurement (Instruments)
Classification: CPC H  G | IPC G  H

Claim 0:
1. A mass spectrometry method using a mass spectrometer including an ion source using an atmospheric pressure ionization method for ionizing a component contained in a liquid sample, the method comprising, to optimize N parameters that affect ionization efficiency in the ion source, N being an integer of 2 or more:
a measurement execution step of repeatedly executing measurement on a sample containing a target component while changing a value of each of the N parameters or a value set of M parameters among the N parameters in a plurality of stages, M being an integer smaller than N; and
a parameter value search step of sequentially finding an optimum value of each of the N parameters or an optimum value set of the M parameters based on a measurement result in the measurement execution step, wherein
in the measurement execution step, a value of at least one parameter whose physical quantity is temperature among the N parameters or a value set of the M parameters including the at least one parameter is changed prior to all parameters whose physical quantities are other than temperature among the N parameters, and
in the parameter value search step, the at least one parameter whose physical quantity is temperature is optimized prior to all the parameters whose physical quantities are other than temperature.