Patent ID: 11873332
Assignee: NOVO NORDISK A/S
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 0:
1. A pharmaceutical formulation comprising:
(a) a monoclonal antibody comprising a mature heavy chain comprising the amino acid sequence of SEQ ID NO:82 except the C-terminal lysine may be absent and a mature light chain comprising the amino acid sequence of SEQ ID NO:86, wherein the antibody is present at a concentration within the range from about 25 mg/mL to about 75 mg/mL;
(b) a histidine buffer present at a concentration of about 20 mM;
(c) sucrose present at a concentration of about 220 to about 260 mM, and
(d) poloxamer 188 (PX188) present at a concentration within the range from about 0.03% to about 0.050% by weight;
wherein the formulation is characterized by a pH within the range from about 5.5 to about 6.5.