Patent ID: 11866709
Assignee: ALNYLAM PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 13:
14. The dsRNA agent of claim 1, wherein the sense and antisense strands comprise nucleotide sequences selected from the group consisting of, (SEQ ID NO: 1182)

5′-UACUCUAUAAAAUCAACCAAAA-3′

and

 

(SEQ ID NO: 1363)

5′-UUUGGUUGAUUUUAUAGAGUAUA-3′;

 

(SEQ ID NO: 1177)

5′-AUACUCUAUAAAAUCAACCAA-3′

and

 

(SEQ ID NO: 1358)

5′-UUGGUUGAUUUUAUAGAGUAUAA-3′;

 

(SEQ ID NO: 1166)

5′-AUGGAAGGUUAUACUCUAUAA-3′

and

 

(SEQ ID NO: 1347)

5′-UUAUAGAGUAUAACCUUCCAUUU-3′;

 

(SEQ ID NO: 43)

5′-CAACCAAAAUGUUGAUCCA-3′

and

 

(SEQ ID NO: 105)

5′-UGGAUCAACAUUUUGGUUG-3′;

 

(SEQ ID NO: 28)

5′-CAAAAUGUUGAUCCAUCCA-3′

and

 

(SEQ ID NO: 90)

5′-UGGAUGGAUCAACAUUUUG-3′;

 

(SEQ ID NO: 1172)

5′-UGGAAGGUUAUACUCUAUAAA-3′

and

 

(SEQ ID NO: 1353)

5′-UUUAUAGAGUAUAACCUUCCAUU-3′;

 

(SEQ ID NO: 1160)

5′-GUCUCAAAAUGGAAGGUUAUA-3′

and

 

(SEQ ID NO: 1341)

5′-UAUAACCUUCCAUUUUGAGACUU-3′;

and

 

(SEQ ID NO: 1144)

5′-AUCCAUCCAACAGAUUCAGAA-3′

and

 

(SEQ ID NO: 325)

5′-UUCUGAAUCUGUUGGAUGGAUCA-3′.