Patent ID: 11938418
Assignee: CYTIVA SWEDEN AB
Field: Chemical engineering (Chemistry)
Classification: CPC B  G | IPC B  G

Claim 6:
7. A method for controlling a chromatography system comprising at least one column, comprising the steps of:
determining a saturation level of the at least one chromatography column, wherein the determining of the saturation level comprises (i) providing the at least one chromatography column in an unloaded state, and measuring a first pressure at the inlet of the at least one unloaded chromatography column, (ii) loading a sample in the at least one unloaded chromatography column to produce at least one loaded chromatography column, and measuring a second pressure at the inlet from the at least one loaded chromatography column, and (iii) comparing the first and second pressure measurement to determine the saturation level; and
stopping the loading of the sample and initiating a column wash step if the level of saturation has reached a saturation point level, wherein the level of saturation is continuously monitored during a chromatography process by measuring the second pressure continuously.