Patent ID: 11965881
Assignee: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
Field: Measurement (Instruments)
Classification: CPC G  B | IPC B  G

Claim 19:
20. A nanosensor for detecting the presence of an active protein in a sample, said nanosensor comprising:
a central carrier particle;
a first particle connected to said central carrier particle via an oligopeptide linkage, said oligopeptide linkage comprising a supramolecular recognition sequence, said protein having specific binding to said supramolecular recognition sequence without chemical modification or enzymatic cleavage of said linkage; and
a second particle directly attached to said central carrier particle via a non-cleavable linkage;
wherein at least one of said first and second particles is a detectable particle and the other of said first and second particles is a quencher particle; and
wherein said detectable particle and quencher particle are separated by a distance that enables Forster resonance energy transfer.