Patent ID: 11883498
Assignee: PURDUE RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 0:
1. A conjugate of the formula B-L-A, wherein B is an LHRH-R binding antagonist of the formula, wherein
each R1 is independently halogen, C1-C6 alkyl or —OC1-C6 alkyl;
each R2 is independently H, C1-C6 alkyl or C3-C6 cycloalkyl;
R3 is C1-C6 alkyl, C3-C6 cycloalkyl, C6-C10 aryl or C1-C6 alkyl-(C6-C10 aryl);
R4 is C1-C6 alkyl;
each R5 is independently selected from the group consisting of halogen, C1-C6 alkyl, —OC1-C6 alkyl, —SC1-C6 alkyl and —OC6-C10 aryl;
X and Y are each independently N, CH or CR1; provided that when X is N, Y is CH or CR1, and when Y is N, X is CH or CR1;
m is an integer from 0 to 4;
n is an integer from 0 to 3; and
* represents a covalent bond to L;
L is a linker; and
A is an imaging agent;

or a pharmaceutically acceptable salt thereof.