Patent ID: 11938179
Assignee: NOVAVAX, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 0:
1. A multivalent immunogenic polypeptide comprising
(i) a binary toxin (CDT) portion having an amino acid sequence that compises SEO ID NO: 22 or an amino acid sequence having at least 90% homology to SEQ ID NO: 22;
(ii) a Toxin A portion having an amino acid sequence that comprises SEQ ID NO:24 or an amino acid sequence having at least 90% homology to SEQ ID NO: 24;
(iii) a first Toxin B portion having an amino acid sequence that comprises SEQ ID NO: 23 or an amino acid sequence having at least 90% homology to SEQ ID NO: 23; and
(iv) a second Toxin B portion having an amino acid sequence that comprises SEO ID NO: 25 or an amino acid sequence having at least 90% homology to SEQ ID NO: 25;
wherein each portion is from a C. difficile toxin protein.