Patent ID: 11926843
Assignee: LIFEEDIT THERAPEUTICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 12:
13. A method for cleaving and/or modifying a target DNA sequence, comprising contacting the target DNA sequence with:
a) an RNA-guided nuclease (RGN) polypeptide, wherein said RGN comprises an amino acid sequence:
(i) having at least 95% sequence identity to any one of SEQ ID NOs: 11, 27, 45 or 54;
(ii) having at least 98% sequence identity to SEQ ID NOs: 1 or 19; or
(iii) set forth as SEQ ID NO: 36;

and
b) one or more guide RNAs capable of hybridizing to the target DNA sequence
thereby cleaving and/or modifying said target DNA sequence to obtain a modified target DNA sequence.