Patent ID: 11952364
Assignee: TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 18:
19. A method for preparing the compound of claim 1, isomers thereof or their pharmaceutically acceptable salts or solvates thereof, which comprises:
(a) reacting a compound of formula A, , with a compound of formula B in the presence of a condensing reagent to form an amide,, , to obtain a compound of formula C, , or (a′) reacting a compound of formula A, , with a compound of formula D in the presence of a condensing reagent to form an amide,, , to obtain a compound of formula E,, , the compound of formula E is subjected to a Suzuki coupling reaction to obtain the compound of formula C; and
(b) deprotecting the compound of formula C to obtain the compound of formula I, , wherein R1 to R5 are as defined in claim 1.