Patent ID: 11932708
Assignee: MOCHIDA PHARMACEUTICAL CO., LTD.
Field: Medical technology (Instruments)
Classification: CPC C  A | IPC A  C

Claim 1:
2. A method of manufacturing a crosslinked alginic acid, comprising mixing an alginic acid derivative of formula (I) with an alginic acid derivative of formula (II) and performing a Huisgen reaction to obtain the crosslinked alginic acid according to claim 1, wherein in formula (I):, (ALG) is alginic acid; —NHCO— is an amide bond via any carboxyl group of alginic acid; -L1- is a divalent linker selected from the group consisting of the following partial structural formula excluding the parts outside the cutting lines at both ends of each formula:, and Akn is a cyclic alkyne group selected from the group consisting of the following partial structural formula, excluding the part to the right of the cutting line in each formula:, in which the asterisks are chiral centers; and
in formula (II):, (ALG) is alginic acid; —NHCO— is an amide bond via any carboxyl group of alginic acid; and -L2- is a divalent linker selected from the group consisting of the following partial structural formula, excluding the parts outside the cutting lines at both ends of each formula:,