Patent ID: 11925467
Assignee: UNIVERSITY HEALTH NETWORK
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A

Claim 14:
15. A system for identifying the likelihood of CRT response for a patient to guide CRT candidate selection, wherein the system comprises:
an input interface for receiving ECG data obtained from the patient;
an output interface for providing a measure of likelihood of CRT response for the patient; and
a processing unit coupled to the input and the output interfaces, the processing unit being configured to:
analyze time-domain ECG data in the ECG data obtained from the patient to detect abnormal QRS peaks using a sliding window;
determine a QRS peak (QRSp) score by quantifying the abnormal QRS peaks in the sliding window of the time-domain ECG data;
determine a measure of likelihood of CRT response for the patient based on the QRSp score by inputting the QRSp score into a statistical classification model to obtain a probability of CRT response for that patient; and
provide an indication that the patient is a candidate for CRT based on the measure of likelihood of CRT response,

wherein the statistical classification model is generated using QRSp scores from patients with heart failure who do not respond to CRT and patients with heart failure who respond to CRT;
wherein the measure of likelihood of CRT response is used to identify candidates likely to respond to CRT; and
wherein a treatment regimen for the patient is determined in response to the indication that the patient is a candidate for CRT, wherein the treatment regime includes performing CRT on the patient.