Patent ID: 11919976
Assignee: SHANDONG FOCUSFREDA BIOTECH CO., LTD
Field: Macromolecular chemistry, polymers (Chemistry)
Classification: CPC C  Y | IPC C

Claim 0:
1. A preparation and purification method for cationic quaternary ammonium salt of sodium hyaluronate in homogeneous medium, comprising the following steps:
adding a homogeneous solvent and a sodium hyaluronate solid to a vessel, heating the vessel until the contents are dissolved to form a homogeneous system, adding an aqueous solution of 2,3-epoxypropyltrimethylammonium chloride to the homogeneous system, then adding a base catalyst, and stirring at a preset temperature to carry out a graft reaction for obtaining a graft product, wherein the 2,3-epoxypropyltrimethylammonium chloride is grafted to the oxygen atom of the hydroxymethyl group of the sodium hyaluronate,
wherein the homogeneous solvent is a mixture of HMF and H2O (HMF-H2O).