Patent ID: 11963972
Assignee: EMORY UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  Y | IPC A

Claim 2:
3. A method for treating a host infected with Zika, preventing an Zika infection, or reducing the biological activity of an Zika infection in a host, comprising administering an effective treatment or preventative amount of a compound or salt thereof to a patient in need of treatment or prevention thereof wherein the compound is sulfasalazine, ipsalazide, balsalazide, or a sulfasalazine analog of the formula:, wherein
X is pyridyl, phenyl, phenyl-substituted by lower alkyl, lower alkoxy, halogen, hydroxy, or nitro, furyl, pyrrolyl, quinolyl, pyrimidyl, thienyl or imidazolyl;
R, R1 and R2 are independently H, C1-6 alkyl, C1-6 aminoalkyl or, A is H, C1-6 alkyl, C1-6 aminoalkyl, amino, alkoxy, halo or CF3; and
n is 0 to 4, wherein
the term pyridyl means 2-pyridyl, 3-pyridyl and 4-pyridyl;
halo is chloro, bromo, iodo, or fluoro; and amino is —NH2, —NH—C(NH2)—NH or,