Patent ID: 11905562
Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 0:
1. A method of treating a patient having one or both of genotypes (a) and (b) and an addictive disease or disorder, comprising:
(i) performing, on a biological sample from the patient having an addictive disease or disorder, a genetic diagnostic assay to detect the presence of one or both of genotypes (a) and (b) in the patient, wherein genotype (a) is the LL genotype of the functional polymorphism serotonin transporter-linked polymorphic region 5-HTTLPR of gene SLC6A4; and genotype (b) is the TT genotype of rs1042173 of gene SLC6A4; and
(ii) administering a therapeutically effective amount of ondansetron to the patient having one or both of genotypes (a) and (b); wherein the addictive disease or disorder is an alcohol-related disease or disorder or an opioid-related disorder.