Patent ID: 11938180
Assignee: SECRETARY OF STATE FOR HEALTH AND SOCIAL CARE, MINISTERIAL CORRESPONDENCE AND PUBLIC ENQUIRIES, DEPARTMENT OF HEALTH AND SOCIAL CARE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 3:
4. The poliovirus-like particle (VLP) of claim 1, which further comprises at least one additional modification relative to the poliovirus particle from which the VLP is derived; wherein said at least one additional modification is in the pocket domain and:
(a) the VLP is derived from a type 1 poliovirus and the at least one additional modification is V1196L;
(b) the VLP is derived from a type 2 poliovirus and the at least one additional modification is Y1159F, V1183L and I1194V; or
(c) the VLP is derived from a type 3 poliovirus and the at least one additional modification is M1260I.