Patent ID: 11964977
Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 30:
31. A compound of formula (I);, , wherein R1, R2, R3 and L are shown in the table below;
L1 is:, , wherein X is oxygen and R′ is hydrogen;
L2 is:, , wherein X is oxygen and R′ is hydrogen;
“Me” is methyl;
“i-Pr” is isopropyl;
“t-Bu” is tert-butyl;
prop-1-en-2-yl is, 2-F-prop-2-yl represents the group, 1, 1-difluoroethyl represents the group, and the group, , , Cmpd.

Ring

#
L
R3
R2
R3
System

271
L1
i-Pr
Me
3,5-di-Cl—Ph
A

 

326
L1
i-Pr
Me

A

 

327
L1
i-Pr
Me

A

 

326-0
L1
i-Pr
Me

A

 

324
L1
i-Pr
Me

A

 

325
L1
i-Pr
Me

A

 

323
L1
i-Pr
Me
t-Bu
A

175
L1
i-Pr
Me
3,5-di-F—Ph
A

A407
L1
i-Pr
Me
2,6-di-F—Ph
A

A406
L1
i-Pr
Me
2,6-di-Cl—Ph
A

A413
L1
i-Pr
Me
2,4-di-F—Ph
A

 

A408
L1

Me
3,5-di-Cl—Ph
A

 

A412
L1
i-Pr
Me
4-F—Ph
A

A410
L1
i-Pr
Me
3-Cl-4-F—Ph
A

A411
L1
i-Pr
Me
3,5-di-Cl—Ph
C

A409
L1
—N(CH3)2
Me
3,5-di-Cl—Ph
A

A414
L1
i-Pr
Me
3,5-di-Cl—Ph
D

306
L1
t-Bu
Me
3,5-di-Cl—Ph
A

297
L1
t-Bu
Me
3,5-di-Cl—Ph
B

365
L1
i-Pr
Me
cyclopropyl
A

 

371
L1
i-Pr
Me

A

 

370
L1
i-Pr
Me

A

 

366
L1
i-Pr
Me
CN
A

 

369
L1
i-Pr
Me

A

 

308
L1
prop-1-en-2-
Me
3,5-di-Cl—Ph
B

yl

364
L1
i-Pr
Me
3,5-di-Cl—Ph
E

352
L1
i-Pr
H
3,5-di-Cl—Ph
A

320-0
L1
i-Pr
Me
3,5-di-F—Ph
F

345
L1
i-Pr
Me
2,3,5-tri-F—Ph
A

344
L1
i-Pr
Me
2,3,5-tri-F—Ph
B

294
L1
i-Pr
Me
3,5-di-Cl—Ph
B

320
L2
i-Pr
Me
3,5-di-F—Ph
A

277
L1
2-F-prop-2-
Me
3,5-di-F—Ph
A

yl

323-0
L1
i-Pr
Me
—CH2CH(CH3)2
A

298-0
L1
t-Bu
CF3
3-Cl—Ph
B

299-0
L1
t-Bu
CF3
3-Cl—Ph
A

299
L1
t-Bu
CF3
3,5-di-Cl—Ph
B

298
L1
t-Bu
CF3
3,5-di-Cl—Ph
A

304-0
L1
i-Pr
3,5-di-Cl—Ph
Cl
B

321
L1
i-Pr
4-F—Ph
3,5-di-F—Ph
A

 

322
L1
i-Pr
Me

A

 

304
L1
i-Pr
Cl
3,5-di-Cl—Ph
B

307
L1
prop-1-en-2-
Me
3,5-di-F—Ph
B

yl

296
L1
i-Pr
CF3
3,5-di-Cl—Ph
B

295
L1
i-Pr
CF3
3,5-di-Cl—Ph
A

293
L1
i-Pr
Me
2,3-di-Cl—Ph
B

276
L1
i-Pr
CF3
3,5-di-F—Ph
A

274
L1
i-Pr
Me
2,3-di-Cl—Ph
A

273
L1
i-Pr
Me
3-F—Ph
A

272
L1
i-Pr
Me
3-Cl-5-F—Ph
A

275
L1
i-Pr
Me
3,5-di-F—Ph
B

279
L1
prop-1-en-2-
Me
3,5-di-F—Ph
A

yl

174
L1
H
H
2,6-di-F—Ph
A

A400
L1
1,1-
Me
3,5-di-Cl—Ph
A

difluoroethyl

A401
L1
CF3
Me
3,5-di-Cl—Ph
A

 

373
L1
i-Pr
Me

A

 

372-0
L1
i-Pr
Me

A

 

A402
L1
i-Pr
Me
3,5-di-Cl—Ph
G

A403
L1
i-Pr
—CH2OH
3,5-di-Cl—Ph
A

A404
L1
i-Pr
—CF2CF3
3,5-di-Cl—Ph
A

394
L1
—OCH3
H
3,5-di-Cl—Ph
A

398
L1
—OCH2CH3
H
3,5-di-Cl—Ph
A

A405
L1
—CHF2
Me
3,5-di-Cl—Ph
A

573
L1
t-Bu
Cl
2,3,5-tri-F—Ph
A

559
L1
i-Pr
—CN
3,5-di-Cl—Ph
A

614
L1
t-Bu
Me
3,5-di-Cl—Ph
AAA

451
L1
—N(CH3)2
CF3
3,5-di-Cl—Ph
A

572
L1
t-Bu
Cl
2,5-di-Cl-4-F—Ph
A

528
L1
i-Pr
Me
2,5-di-Cl-4-F—Ph
A

571
L1
t-Bu
Cl
2,4,5-tri-F—Ph
A

574
L1
t-Bu
Cl
2,3-di-Cl-5-F—Ph
A

A415
L1
i-Pr
Me
3,5-di-Cl—Ph
H

A416
L1
i-Pr
Me
3,5-di-Cl—Ph
I

A417
L1
i-Pr
Me
3,5-di-Cl—Ph
J

A418
L1
i-Pr
Me
3,5-di-Cl—Ph
K

A419
L1
i-Pr
Me
3,5-di-Cl—Ph
L

A420
L1
i-Pr
Me
3,5-di-Cl—Ph
M

560
L1
i-Pr
—CHF2
3,5-di-Cl—Ph
A

305
L1
i-Pr
—CHF2
3,5-di-Cl—Ph
B

 

A421
L1

Me
2,6-di-Cl-4-F
A

 

A422
L1

Me
2,3,5-tri-F—Ph
A

 

420
L1
t-Bu
Cl
3,5-di-Cl—Ph
A

A423
L1
i-Pr
Me
3,5-di-Cl—Ph
N

A424
L1
i-Pr
Me
3,5-di-Cl—Ph
0

523
L1
t-Bu
Me
2,6-di-Cl-4-F—Ph
A

A425
L1
i-Pr
Me
3,5-di-Cl—Ph
P

A426
L1
i-Pr
Me
3,5-di-Cl—Ph
Q

526
L1
t-Bu
Me
2,3-di-Cl-5-F—Ph
A

527
L1
i-Pr
Me
2,4,6-tri-F—Ph
A

524
L1
t-Bu
Me
2,4,6-tri-F—Ph
A

525
L1
t-Bu
Me
2,3,5-tri-F—Ph
A

414-0
L2
i-Pr
Me
3,5-di-Cl—Ph
R

514
L2
i-Pr
Me
3,5-di-Cl—Ph
E

A427
L1
i-Pr
Me
3,5-di-Cl—Ph
S

A428
L1
i-Pr
Me
3,5-di-Cl—Ph
T

A429
L1
i-Pr
Me
3,5-di-Cl—Ph
U

A430
L1
i-Pr
Me
3,5-di-Cl—Ph
V

418
L1
t-Bu
H
3,5-di-Cl—Ph
A

513
L2
i-Pr
Me
3,5-di-Cl—Ph
A

513-0
L2
i-Pr
Me
3,5-di-Cl—Ph
F

 

511
L1

H
3,5-di-Cl—Ph
A

 

512
L1
—N(CH3)2
H
3,5-di-Cl—Ph
A

A431
L1
i-Pr
Me
3,5-di-Cl—Ph
W

 

450
L1

CF3
3,5-di-Cl—Ph
A

 

A432
L1
i-Pr
Me
3,5-di-Cl—Ph
X

A473
L1
i-Pr
Me
3,5-di-Cl—Ph
Y

A433
L1
i-Pr
Me
3,5-di-Cl—Ph
Z

A434
L1
i-Pr
Me
3,5-di-Cl—Ph
AA

A435
L1
i-Pr
Me
3,5-di-Cl—Ph
AB

A436
L1
L1
i-Pr
Me
N/A (H)

A437
L1
i-Pr
Me
3,5-di-Cl—Ph
AC

A438
L1
i-Pr
Me
3,5-di-Cl—Ph
AD

A439
L1
i-Pr
Me
3,5-di-Cl—Ph
AF

A440
L1
i-Pr
Me
3,5-di-Cl—Ph
AG

A441
L1
i-Pr
Me
3,5-di-Cl—Ph
AH

A442
L1
i-Pr
Me
3,5-di-Cl—Ph
AE

A443
L1
i-Pr
Me
3,5-di-Cl—Ph
AJ

A445
L1
i-Pr
Me
3,5-di-Cl—Ph
AK

A446
L1
i-Pr
Me
3,5-di-Cl—Ph
AL

A447
L1
i-Pr
Me
3,5-di-Cl—Ph
AM

A448
L1
i-Pr
Me
3,5-di-Cl—Ph
AO

A449
L1
i-Pr
Me
3,5-di-Cl—Ph
AQ

A450
L1
i-Pr
Me
3,5-di-Cl—Ph
AR

A451
L1
i-Pr
Me
3,5-di-Cl—Ph
AP

A452
L1
i-Pr
Me
3,5-di-Cl—Ph
AS

A472
L1
i-Pr
Me
3,5-di-Cl—Ph
AT

A453
L1
i-Pr
Me
3,5-di-Cl—Ph
AN

A454
L1
i-Pr
Me
3,5-di-Cl—Ph
AU

419
L1
i-Pr
Cl
3,5-di-Cl—Ph
A

397-0
L1
OCH2CH═CH2
Me
3,5-di-Cl—Ph
A

A455
L1
i-Pr
Me
3,5-di-Cl—Ph
AW

A456
L1
i-Pr
Me
3,5-di-Cl—Ph
AX

A457
L1
i-Pr
Me
3,5-di-Cl—Ph
AY

A458
L1
i-Pr
Me
3,5-di-Cl—Ph
AZ

395
L1
—OCHF2
Me
3,5-di-Cl—Ph
A

 

A459
L1

Me
3,5-di-Cl—Ph
A

 

A464
L1
—N(CH3)2
Me
2,6-di-Cl-4-F—Ph
A

A462
L1
—N(CH3)2
Me
2,4,6-tri-F—Ph
A

A463
L1
—N(CH3)2
Me
2,3-di-Cl-5-F—Ph
A

A460
L1
—N(CH3)2
Me
2,3,5-tri-F—Ph
A

A461
L1
—N(CH3)2
Me
2,3,5-tri-Cl—Ph
A

558
L1
i-Pr
—C(O)CH3
3,5-di-Cl—Ph
 A.