Patent ID: 11911483
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A compound represented by formula (I), , wherein
R1 is C1-C5 alkyl, N3, OH, SH, ONH2, NH2, CO2H,, R2 is the side chain residue of an amino acid selected from the group consisting of alanine, β-alanine, γ-aminobutyric acid, arginine, asparagine, aspartic acid, γ-carboxyglutamic acid, citrulline, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, norleucine, norvaline, ornithine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine;
n is 2 3, 4, or 5;, , comprising a polypeptide whose bond to, , is cleavable by cathepsin B;
R3 is NH,, R4 is, L is the residue of a bioactive molecule of the formula L-R3H; and
X is spacer group.