Patent ID: 11946885
Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 13:
14. A method of determining if a capsid preparation has experienced stress-induced damage selected from the group consisting of temperature excursions, a freeze/thaw process, light, agitation, and any combination thereof, said method comprising:
measuring the transverse relaxation rate of solvent R2,m in the capsid preparation; and
determining if the capsid preparation has experienced stress-induced damage by comparing the measured R2,m to a reference transverse relaxation rate of solvent R2,r, wherein the reference R2,r represents an acceptable range for the capsid preparation,
wherein when the measured R2,m is inside the reference R2,r range, the capsid preparation has not experienced substantial stress-induced damage and can be used or distributed.