Patent ID: 11890329
Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 15:
16. The therapeutic regimen according to claim 1, wherein the rAAV is formulated for intrathecal injection to a human subject, to administer a total flat dose of:
(i) about 1.2×1012 to about 6.0×1012 GC or about 6.0×1012 to about 3.0×1013 GC to a human subject ≥4 months to <9 months of age;
(ii) about 2×1012 to about 6.0×1013 or about 1.0×1013 to about 5.0×1013 GC to a human subject ≥9 months to <18 months of age; or
(iii) about 2.2×1012 to about 1.1×1013 GC or about 1.1×1013 to about 5.5×1013 GC to a human subject ≥9 months to <18 months of age.