Patent ID: 11878311
Assignee: PNEUMATIC SCALE CORPORATION
Field: Chemical engineering (Chemistry)
Classification: CPC B  C | IPC B

Claim 14:
15. The apparatus according to claim 1
wherein the single use structure further includes:
at least one annular air tight seal,
wherein the at least one seal operatively extends in operatively sealing relation between the upper disc shaped portion and at least one annular outer wall that extends radially outwardly of at least one of the feed tube and the centrate discharge tube,
wherein the centrate centripetal pump includes a substantially annular centrate pump opening, wherein centrate passes from the centrate pump chamber through the substantially annular centrate pump opening,
wherein the at least one seal is operative to maintain an air pocket within the interior area,
wherein the air in the air pocket isolates the at least one seal from the cell culture batch being processed,
and further comprising:
a flow back pressure regulator in fluid connection with the centrate discharge tube, wherein the flow back pressure regulator is selectively operative to apply back pressure to centrate flow,
a controller, wherein the controller is in operative connection with the flow back pressure regulator, wherein the controller is operative to maintain the air pocket positioned radially inward of the substantially annular centrate pump opening.