Patent ID: 11957793
Assignee: SINTEF TTO AS
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 3:
4. A process for the preparation of nanoparticles of a poly(alkyl cyanoacrylate) homopolymer or copolymer, comprising, in a single step, the anionic polymerisation of an oil-in-water miniemulsion, wherein said miniemulsion comprises
(i) at least one alkyl cyanoacrylate monomer;
(ii) at least one surfactant;
(iii) one or more active agents;
(iv) optionally an anionic polymerisation initiator; and
(v) an anionic and radical inhibitor, wherein the anionic and radical inhibitor is a compound having the following formula:, wherein
R1 is H; and
R3, R4, R5, R6 and R7 are independently selected from the group consisting of —H, —OH, C1-C6 alkoxide, C1-C6 alkyl, halides, carboxylic acid, ketone and aldehyde.