Patent ID: 11913051
Assignee: LIMMATECH BIOLOGICS AG
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A Leishmania host cell comprising:
a. a recombinant nucleic acid encoding a target protein; and
b. a recombinant nucleic acid encoding a heterologous glycosyltransferase, wherein the heterologous glycosyltransferase is an N-acetyl glucosamine transferase that is not from Leishmania and/or galactosyltransferase that is not from Leishmania; wherein the heterologous glycosyltransferase comprises a signal and/or retention sequence, wherein the signal sequence is capable of targeting the heterologous glycosyltransferase to the secretory pathway of the Leishmania host cell, and wherein the retention sequence is capable of retaining the heterologous glycosyltransferase in the Golgi apparatus.