Patent ID: 11951104
Assignee: ZHUHAI LIVZON MICROSPHERE TECHNOLOGY CO. LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. An aripiprazole sustained-release microsphere, comprising aripiprazole or salts thereof and poly(lactide-co-glycolide) copolymer; wherein,
the microsphere is in a spherical reticulate skeleton structure, small reticular holes are distributed in the sphere; and the aripiprazole or salts thereof are filled in the holes;
the microsphere has a mean particle size of less than 20 μm; the aripiprazole or salts thereof has a content of 71%-80% of a total weight of the microsphere;
wherein, the poly(lactide-co-glycolide) copolymer has an intrinsic viscosity of 0.2-0.55 dL/g; a polydispersity index of 1.0-3.0; and a weight-average molecular weight of 15000-60000; and
a molar ratio of lactide to glycolide in the poly(lactide-co-glycolide) copolymer is 50:50-65:35.