Patent ID: 11878970
Assignee: PETRA PHARMA CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 62:
63. The compound of claim 62, or pharmaceutically acceptable salt thereof, wherein R1 is a group of the formula:, R2 is an optionally substituted bicyclic ring selected from 1,3-benzodioxole, 2,3-dihydro-1,4-benzodioxine, isoindolin-1-one, or benzo[d]oxazol-2(3H)-one, or an optionally substituted bicyclic heteroaryl wherein a phenyl, pyridine, pyrazine, pyrimidine, or pyridazine ring is fused to a pyrrole, furan, thiophene, pyrazole, isoxazole, imidazole, oxazole, thiazole, triazole, pyridine, pyrazine, pyrimidine, or pyridazine ring; wherein the optionally substituted bicyclic ring is optionally substituted with one to three substituents each independently selected from C1-C6 alkyl; the optionally substituted bicyclic heteroaryl is optionally substituted with one to three substituents each independently selected from 13 CN, halogen, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, an optionally substituted C1-C6 alkyl, an optionally substituted C3-C5 cycloalkyl, an optionally substituted heterocycle selected from pyrrolidine, pyrrolidinone, piperidine or morpholine, an optionally substituted phenyl, or an optionally substituted heteroaryl selected from pyrazole, isoxazole, isothiazole, imidazole, oxazole, or thiazole; wherein the optionally substituted C1-C6 alkyl is optionally substituted with a 13 CN, 13 OH, or C1-C3alkoxy; the optionally substituted C3-C5 cloalkyl, phenyl, heterocycle or heteroaryl is each optionally substituted with one to three substituents each independently selected from halogen, C1-C3 alkyl, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, -NR10R10, 13 OH or 13 CN;
R3 is -13 H, 13 CN, or C1-C3 alkyl;
R4, and R are each -H;
R5 is 13 H, halogen, C1-C3 alkyl or C1-C3 haloalkyl;
R6 is 13 H or halogen;
R7 is 13 CN, methyl or trifluoromethyl, each R9, is independently 13 H, halogen, methyl, or C1-C3 haloalkyl; and
each R10 is independently 13 H or C1-C3 alkyl.