Patent ID: 11932700
Assignee: INNOVATIVE CELLULAR THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A method of stimulating a T cell-mediated immune response and treating colorectal cancer in a human patient, the method comprising:
contacting a population of cells comprising guanylate cyclase 2C (GUCY2C) comprising the amino acid sequence of SEQ ID NO: 33, in a human patient with a population of modified T cells comprising a chimeric antigen receptor (CAR),
and stimulating a T cell-mediated immune response and treating colorectal cancer in a human patient,
wherein the CAR comprises an extracellular domain, a transmembrane domain, and an intracellular domain, the extracellular domain comprising the amino acid sequences SEQ ID NO: 14.