Patent ID: 11891431
Assignee: TAKEDA PHARM LIMITED CEUTICAL COMPANY LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  B | IPC A  B  C

Claim 3:
4. The composition according to claim 1, wherein step (e) comprises the sub-steps of:
(i) separating the SiO2 from the first suspension using a filter press thereby forming a filtrate, and a filter cake;
(ii) washing the filter cake with at least 3 filter press dead volumes of a wash buffer containing phosphate and acetate, wherein the pH of the wash buffer is adjusted with from about 50 mL to about 200 mL of glacial acetic acid per 1000 L of wash buffer, thereby forming a wash solution; and
(iii) combining the filtrate of sub-step (i) with the wash solution of sub-step (ii), thereby forming the clarified suspension.