Patent ID: 11926596
Assignee: KADMON CORPORATION, LLC
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound having the formula III:, wherein:
R1 is selected from the group consisting of lower alkyl, C3-C6 cycloalkyl, and R10O(CH2)2 wherein R10 is methyl;
R2 is phenyl or pyridyl, each of which may be unsubstituted or optionally substituted with 1 to 3 substituents independently selected from the group consisting of halo, hydroxy, lower alkyl, lower alkoxy, nitro, cyano, C1-C3 perfluoro alkyl, C1-C3 perfluoro alkoxy, carboxyl, RR′N—, RR′NCO—, RCONH—, RCONR′—, RO2C—, aryl-O— and heteroaryl-O—;
R3 is selected from H, lower alkyl, substituted lower alkyl, and RR′N—(C2-4 alkyl)-; and
each R and R′ is independently selected from H, lower alkyl, and C3-C6 cycloalkyl, or alternatively, R and R′ taken together form a 5 to 6 membered heterocyclic ring;
wherein substituted lower alkyl is a C1-4 alkyl having from one to three substituents independently selected from halo, hydroxy, lower alkoxy, amino, nitro, cyano, perfluoro lower alkyl, perfluoro lower alkoxy and carboxyl;
or a pharmaceutically acceptable salt thereof.