Patent ID: 11918573
Assignee: NICOX OPHTHALMICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A topical ophthalmic formulation comprising cetirizine hydrochloride or dihydrochloride in an amount of 0.05% to 0.5% (w/v) calculated as cetirizine free base, wherein cetirizine is the only active agent in the formulation and the cetirizine is formulated in a vehicle comprising (a) a demulcent and/or viscosity enhancing polymer, (b) a preservative and (c) a surfactant comprising a polysorbate at a concentration of 0.02 to 0.1% (w/v), (d) a carrier comprising polyethylene glycol, and (e) water, wherein the formulation has a pH of about 5.5 to 7.5, a viscosity of from 1-50 centipoise and an osmolality of about 225-400 mOsm/kg, and wherein the formulation does not contain a cyclodextrin.