Patent ID: 11905525
Assignee: MODERNATX, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 10:
11. The method of claim 10, wherein the mRNA comprises pseudouridine (ψ), pseudouridine (ψ) and 5-methyl-cytidine (m5C), 1-methyl-pseudouridine (m1ψ), 1-methyl-pseudouridine (m1ψ) and 5-methyl-cytidine (m5C), 2-thiouridine (s2U), 2-thiouridine and 5-methyl-cytidine (m5C), 5-methoxy-uridine (mo5U), 5-methoxy-uridine (mo5U) and 5-methyl-cytidine (m5C), 2′-O-methyl uridine, 2′-O-methyl uridine and 5-methyl-cytidine (m5C), N6-methyl-adenosine (m6A), N6-methyl-adenosine (m6A) and 5-methyl-cytidine (m5C), pseudouridine (ψ), N1-methylpseudouridine (m1ψ), 2-thiouridine, 4′-thiouridine, 5-methylcytosine, 2-thio-1-methyl-1-deaza-pseudouridine, 2-thio-1-methyl-pseudouridine, 2-thio-5-aza-uridine, 2-thio-dihydropseudouridine, 2-thio-dihydrouridine, 2-thio-pseudouridine, 4-methoxy-2-thio-pseudouridine, 4-methoxy-pseudouridine, 4-thio-1-methyl-pseudouridine, 4-thio-pseudouridine, 5-aza-uridine, dihydropseudouridine, 5-methoxyuridine, or 2′-O-methyl uridine, or combinations thereof.