Patent ID: 11873289
Assignee: MYOKARDIA, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC A  C  B  Y | IPC B  C

Claim 25:
26. A process for preparation of a compound of formula Z,, wherein R1 is hydrogen, C1-C6 alkyl optionally substituted with one or more halogen atoms, C3-C6 cycloalkyl, or arylalkyl;
R2 is hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, arylalkyl, or aryl;
R3 is C1-C6 alkyl substituted with one or more halogen atoms;
wherein each halogen atom is independently selected from fluorine, chlorine, bromine, and iodine;
comprising the steps of:
a) decarboxylating a compound of formula X to obtain a compound of formula Y; and, b) iodinating the compound of formula Y to obtain the compound of formula Z.