Patent ID: 11912770
Assignee: SHANGHAI NOVAMAB BIOPHARMACEUTICALS CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 5:
6. The anti-PD-L1 single-domain antibody of claim 1, which is a tetravalent anti-PD-L1 single-domain antibody, which has the following structure:
A-L-P˜P-L-A;
wherein,
element P is a monomer of an anti-PD-L1 single-domain antibody whose VHH chain comprises the following 3 CDRs wherein CDR1 comprises SEQ ID NO: 5, CDR2 comprises SEQ ID NO: 6, and CDR3 comprises SEQ ID NO: 7;
element A is a sequence comprising SEQ ID NO: 14;
L represents a linker;
“—” represents a peptide bond; and
“˜” represents a disulfide bond.