Patent ID: 11969428
Assignee: THOMAS DIACOVO
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G | IPC A  C  G

Claim 0:
1. A method for treating or ameliorating the effects of a lymphoid malignancy comprising administering to a subject in need thereof an effective amount of a small molecule to selectively inhibit phosphoinositide 3-kinase-delta (PI3Kd) and phosphoinositide 3-kinase-gamma (PI3Kg) isoforms, wherein the small molecule to selectively inhibit PI3Kd and PI3Kg isoforms is CAL-130, wherein the lymphoid malignancy is T-cell acute lymphoblastic leukemia (T-ALL) or T-cell acute lymphoblastic lymphoma, and wherein the CAL-130 has the chemical structure of:,