Patent ID: 11912786
Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 0:
1. A compound having the structure of Formula D-XIII, or a pharmaceutically acceptable salt thereof:, wherein,
R1 is H, or C1-C6 alkyl;
X1 is S (sulfur) or O (oxygen);
X2 is CH2;
R2a and R2b are each H;
—U— is —C(═O)NH—;
R3 is C1-C3 alkyl, or C1-C3 fluoroalkyl;
R4 is —N(R5)2;
each R5 is independently selected from H, C1-C3 alkyl, and C1-C3 haloalkyl;
R6 is —C(═O)NHR7;
R7 is selected from the group consisting of C1-C6 alkyl, C1-C6 haloalkyl, a substituted or unsubstituted C3-C10 cycloalkyl, a substituted or unsubstituted C2-C10 heterocycloalkyl, a substituted or unsubstituted aryl, and a substituted or unsubstituted heteroaryl;
wherein each heterocycloalkyl is independently selected from the group consisting of a monocyclic, fused bicyclic, and bridged bicyclic ring, wherein the heterocycloalkyl comprises one or more heteroatoms selected from the group consisting of O, N, and S; and
wherein each heteroaryl is independently selected from the group consisting of a monocyclic and fused bicyclic ring, wherein the heteroaryl is a 5- to 14-membered ring system comprising one to thirteen carbon atoms, one to six heteroatoms selected from the group consisting of O, N, and S.