Patent ID: 11897880
Assignee: JANSSEN PHARMACEUTICA NV
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. The compound of claim 5, wherein
R1 is hydrogen;
R2 is hydrogen and R3 is cyclopropyl-methyl-;
alternatively, R2 and R5 are taken together with the carbon atoms to which they are bound to form;, R4 is hydrogen;
R5 is selected from the group consisting of 4-(methoxy-carbonyl-amino)-phenyl, 2-fluoro-6-amino-pyridin-3-yl, 2-chloro-6-amino-pyridin-3-yl, 2-fluoro-6-amino-pyridin-4-yl, indazol-5-yl, benzimidazol-5-yl, and benzothiazol-5-yl;
a is 2;
one R6 is 11-chloro and the other R6 is 12-fluoro;
R7 is hydrogen, and R8 and R9 are each methyl;
alternatively, R7 is hydrogen, and R8 and R9 are taken together with the carbon atom to which they are bound to form a ring structure selected from the group consisting of cycloprop-1,1-diyl, cyclobut-1,1-diyl and cyclopent-1,1-diyl;
or a pharmaceutically acceptable salt thereof.