Patent ID: 11874282
Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method for diagnosing and treating preeclampsia or a preeclampsia-related condition selected from the group consisting of eclampsia, Hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome and proteinuria in a pregnant subject, said method comprising the steps of
(a) measuring the amount of IGFBP-7 (Insulin-like Growth Factor Binding Protein 7) polypeptide in a sample from the subject,
(b) comparing the measured amount of the biomarker to a reference,
(c) based on the comparison of step (b), identifying the subject as having preeclampsia or a preeclampsia-related condition when the measured amount is increased compared to the reference; and
(d) administering one or more of corticosteroids, magnesium sulfate and blood pressure reducing agents to the subject identified as having preeclampsia or a preeclampsia-related condition.