Patent ID: 11952634
Assignee: MEDIVATION PROSTATE THERAPEUTICS LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 18:
19. The method according to claim 18, comprising:
(a) determining the Basal Centroid classifier score and the Luminal A Centroid classifier score of the sample from the expression of the set of intrinsic genes listed in Table 1 using the PAM 50 classifier; and
(b) calculating a Weighted Basal and Luminal A classifier score from the Basal Centroid classifier score and the Luminal A Centroid classifier score according to the following equation:

Weighted Basal and Luminal A classifier score=−0.25(Basal Centroid classifier score)+0.27(Luminal A Centroid classifier score); and

wherein the breast cancer treatment is administered to the subject if the Weighted Basal and Luminal A classifier score is greater than −0.3.