Patent ID: 11939566
Assignee: DEKA PRODUCTS LIMITED PARTNERSHIP
Field: Biotechnology (Chemistry)
Classification: CPC C  A  B | IPC A  B  C

Claim 8:
9. A tissue enclosure enabling creation, maintenance, and monitoring of tissue comprising:
an incoming chamber admitting a first material, the incoming chamber emitting the first material in response to a differential pressure within the tissue enclosure;
a core including a cavity, the core having at least one monitoring area and at least one opening into the cavity, the core accommodating at least one material ingress and at least one material egress, the core containing the tissue supported in a granular media, and metabolism products from the tissue;
at least one first filtration zone operably positioned between the incoming chamber and the core, the filtration zone subjecting the first material to at least one filter having a first pore size based at least on the first material, the filtration zone emitting first filtered contents to the core based at least on the first material and the first pore size;
at least one second filtration zone operably coupled with the core, the at least one second filtration zone subjecting the first filtered material, the media, the tissue, and the metabolism products to at least one filter having a second pore size based at least on the first filtered material, the media, the tissue, and the metabolism products, the filtration zone emitting second filtered contents based at least on the first filtered material, the media, the tissue, the metabolism products, and the second pore size; and
an effluent chamber directly engaged with said at least one second filtration zone, said effluent chamber maintained at a pressure different than a pressure of said core forming a pressure differential causing the second filtered contents to flow from said core into said effluent chamber, the effluent chamber managing the filtered contents,
wherein the tissue enters the cavity through the at least one opening, and
wherein the tissue is confined within the cavity by the at least one first filtration zone and the at least one second filtration zone, and
wherein the life of the tissue is maintained by the first material entering the cavity through the at least one material ingress and by the metabolism products exiting the cavity through the at least one material egress, and
wherein the tissue is monitored through the at least one monitoring area.