Patent ID: 11911631
Assignee: THOMAS JEFFERSON UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 17:
18. A multimodality treatment system comprising:
a biocompatible expandable balloon configured to fill a resection cavity;
a magnetic material capable of insertion within the biocompatible expandable balloon for heating a tissue around the resection cavity; and
a central catheter configured to extend from outside of the patient to an interior of the biocompatible expandable balloon, the central catheter adapted and configured for coupling with a remote afterloader for insertion of a radiation source into an interior of the biocompatible expandable balloon;
the system being characterized by further comprising a non-contacting external induction coil adapted to apply an external magnetic field surrounding the balloon, the magnetic field:
inductively coupling to and thereby heating the magnetic material within the biocompatible expandable balloon to produce a substantially non-ablative temperature distribution of about 40-45° C. for about 30-60 mins in the tissue around the resection cavity simultaneously with delivery of radiation from the radiation source; and
having a frequency in the range of 50 kHz to 500 kHz.