Patent ID: 11860120
Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
Field: Measurement (Instruments)
Classification: CPC G  H | IPC G  H

Claim 8:
9. A method, comprising:
forming a plurality of biologically sensitive field-effect transistors (BioFETs) on a semiconductor layer that is disposed on a dielectric layer, each of the BioFETs comprising source/drain regions, a channel region between the source/drain regions, and a gate structure on a first side of the channel region;
forming a plurality of first elongated heaters in the semiconductor layer;
forming an interconnect structure over the BioFETs, wherein the interconnect structure comprises metal lines and a plurality of second elongated heaters, and the second elongated heaters have a thermal conductivity lower than the metal lines, and the second elongated heaters have a rectangular profile from a top view, wherein from the top view the first elongated heaters extend along a first direction, the second elongated heaters extend along a second direction perpendicular to the first direction, and the BioFETs are respectively in regions defined by the first elongated heaters and the second elongated heaters;
etching the dielectric layer to form a sensing well exposing a second side of the channel region;
forming a biosensing film in the sensing well;
forming a coating of a selective binding agent over the biosensing film; and
forming fluid channel walls over the coating of the selective binding agent, wherein one of the fluid channel walls forms a horizontal interface with the coating of the selective binding agent, and an entirety of the horizontal interface vertically overlaps with one of the plurality of first elongated heaters in the semiconductor layer.