Patent ID: 11905543
Assignee: TRAIT BIOSCEINCES, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An in vivo method for the generation of water-soluble cannabinoids, comprising the steps of:
(a) establishing a tobacco cell suspension culture;
(b) introducing a cannabinoid having at least one glycosylation site to said tobacco cell suspension culture, wherein said cannabinoid is selected from the group consisting of: cannabigerol (CBG), cannabigerolic acid (CBGA), cannabidiol (CBD), and cannabidiolic acid (CBDA);
(c) incubating said cannabinoid in said tobacco cell suspension culture, thereby glycosylating the cannabinoid; and
(d) isolating a cannabinoid glycoside from said tobacco cell suspension culture, wherein said cannabinoid glycoside is selected from the group consisting of CBG-glycoside, CBD-glycoside, CBGA-glycoside and CBDA-glycoside;
wherein said tobacco cell suspension culture is a Nicotiana tabacum cell suspension culture or a Nicotiana benthamiana cell suspension culture.