Patent ID: 11873508
Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Field: Macromolecular chemistry, polymers (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. A method of preparing a polymeric microsphere comprising a thermally responsive monomer crosslinked with a functional group monomer, wherein the functional group monomer comprises a primary amine functional group, wherein the method comprises the steps of:
i. providing a microemulsion mixture of the thermally responsive monomer, the functional group monomer and the cross-linker stirring at a temperature for a period of time;
ii. polymerizing said microemulsion mixture with an initiator stirring at the temperature for a period of time to thereby synthesize said polymeric microsphere; and,
iii. coating the entire polymeric microsphere with a polymer coating selected from the group consisting of polymerized catecholamines, dopamine, L-3,4-dihydroxyphenylalanine, epinephrine, and norepinephrine, wherein the microsphere has a particle size in a range of 100 μm to 200 μm.