Patent ID: 11911355
Assignee: SEN-JAM PHARMACEUTICAL INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 4:
5. A method of inhibiting tolerance to an opioid by a human subject in need thereof, comprising:
administering to the subject an effective amount of a pharmaceutical composition during an opioid withdrawal period, wherein the pharmaceutical composition consists of:
a) about 1200 mg to about 1600 mg of ibuprofen,
b) about 0.5 mg to about 3 mg ketotifen, and
c) a pharmaceutical carrier, a pharmaceutical excipient, a sweetening agent, a flavoring agent, a taste masking ingredient, a diluent, alum, a stabilizer, a buffer, a coloring agent, a breath neutralizer, a proton pump inhibitor, an emulsifying agent, a suspending agent and combinations thereof,
wherein tolerance to an opioid is inhibited in the human subject.