Patent ID: 11965189
Assignee: NOVOZYMES A/S
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 42:
43. A method for obtaining a cellobiohydrolase variant, comprising introducing into a parent cellobiohydrolase a substitution at one or more positions corresponding to positions 113, 157, 159, 199, 250, 274, 318, 325, 328, 347, 349, 358, 360, 380, 391, 393, 394, 412, and 430 of the polypeptide of SEQ ID NO: 1, wherein the variant has: (1) cellobiohydrolase activity, (2) at least 90%, but less than 100%, sequence identity to SEQ ID NO: 1, and (3) an increased thermal activity or increased thermostability relative to the cellobiohydrolase of SEQ ID NO: 1.