Patent ID: 11932845
Assignee: GENOMATICA, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 1:
2. The microbial organism of claim 1, wherein said microbial organism further comprises a genetic modification selected from:
(A) a genetic modification that increases expression of phosphoenolpyruvate carboxylase relative to the microbial organism in the absence of the genetic modification;
(B) a genetic modification that increases expression of alpha-ketoglutarate dehydrogenase relative to the microbial organism in the absence of the genetic modification;
(C) a genetic modification that increases expression of a non-phosphotransferase (PTS) glucose uptake system relative to the microbial organism in the absence of the genetic modification;
(D) a genetic modification that decreases expression of succinyl-CoA synthetase relative to the microbial organism in the absence of the genetic modification;
(E) a genetic modification that decreases expression of an acyl coenzyme A thioesterase relative to the microbial organism in the absence of the genetic modification;
(F) a genetic modification that decreases expression of a non-energy-producing NADH dehydrogenase relative to the microbial organism in the absence of the genetic modification;
(G) a genetic modification that decreases expression of a cytochrome oxidase relative to the microbial organism in the absence of the genetic modification; and
(H) a combination of two or more, three or more, four or more, five or more, six or all of the genetic modifications of parts (A)-(G).