Patent ID: 11926620
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 2:
3. A method of making the 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-thioxobenzo[d]oxazol-3(2H)-yl)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid compound of claim 1, the method comprising:
stirring a solution of ciprofloxacin, formaldehyde, and triethylamine in ethanol to obtain a reaction mixture;
adding 2-mercaptobenzoxazole to the reaction mixture and stirring with reflux;
cooling the reaction mixture at room temperature to obtain a solid; and
obtaining the 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-thioxobenzo[d]oxazol-3(2H)-yl)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid compound.