Patent ID: 11897898
Assignee: BIOGEN MA INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of Formula (F):, or a pharmaceutically acceptable salt thereof, wherein:
n is selected from 0, 1 and 2;
L is selected from C3-5 alkylene and C3-5 alkenylene, wherein said C3-5 alkylene and C3-5 alkenylene are optionally substituted with one or two R2;
R1 in each occurrence is independently selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, carbocyclyl, heterocyclyl, halo, —CN, —C(O)R1a, —C(O)OR1a, —C(O)N(R1a)2, —N(R1a)2, —N(R1a)C(O)R1a, —N(R1a)C(O)OR1a, —N(R1a)C(O)N(R1a)2, —N(R1a)S(O)2R1a, —OR1a, —OC(O)R1a, —OC(O)N(R1a)2, —SR1a, —S(O)R1a, —S(O)2R1a, —S(O)N(R1a)2, and —S(O)2N(R1a)2, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, carbocyclyl, and heterocyclyl, are optionally and independently substituted with one or more R10;
R1a in each occurrence is independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6alkynyl, carbocyclyl, and heterocyclyl, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, carbocyclyl, and heterocyclyl in each occurrence are optionally and independently substituted with one or more R10;
R10 in each occurrence is independently selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, carbocyclyl, heterocyclyl, halo, —CN, —C(O)R10a, —C(O)OR10a, —C(O)N(R10a)2, —N(R10a)2, —N(R10a)C(O)R10a, —N(R10a)C(O)OR10a, —N(R10a)C(O)N(R10a)2, —N(R10a)S(O)2R10a, —OR10a, —OC(O)R10a, —OC(O)N(R10a)2, —SR10a, —S(O)R10a, —S(O)2R10a, —S(O)N(R10a)2, and —S(O)2N(R10a)2, wherein said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, carbocyclyl, and heterocyclyl in each occurrence are optionally and independently substituted with one or more halo, —CN, —C(O)R10a, —C(O)OR10a, —C(O)N(R10a)2, —N(R10a)2, —N(R10a)C(O)R10a, —N(R10a)C(O)OR10a, N(R10a)C(O)N(R10a)2, —N(R10a)S(O)2RR10a, —OR10a, —OC(O)R10a, —OC(O)N(R10a)2, —SR10a, —S(O)R10a, —S(O)2R10a, —S(O)N(R10a)2, and —S(O)2N(R10a)2;
R10a in each occurrence is independently selected from H, C1-6alkyl, C2-6 alkenyl, C2-6alkynyl, carbocyclyl, and heterocyclyl;
R2 in each occurrence is independently selected from C1-6alkyl, —CN, —C(O)R2a, —C(O)OR2a, —C(O)N(R2a)2, —NO2, —N(R2a)2, —N(R2a)C(O)R2a, —N(R2a)C(O)OR2a, —N(R2a)C(O)N(R2a)2, —N(R2a)S(O)2R2a, —OR2a, —OC(O)R2a, —OC(O)N(R2a)2, —SR2a, —S(O)R2a, —S(O)2R2a, —S(O)N(R2a)2, and —S(O)2N(R1a)2, wherein said C1-6 alkyl is optionally substituted with one or more R20;
R2a in each occurrence is independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6alkynyl, carbocyclyl, and heterocyclyl wherein said C1-6 alkyl, C2-6 alkenyl, C2-6alkynyl, carbocyclyl, and heterocyclyl in each occurrence are optionally and independently substituted with one or more R20; and
R20 in each occurrence is independently selected from C1-6 alkyl, halo and —OR20a;
R20a in each occurrence is independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6alkynyl, carbocyclyl, and heterocyclyl; and
R3 is H or C1-4 alkyl.