Patent ID: 11926843
Assignee: LIFEEDIT THERAPEUTICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 5:
6. The vector of claim 4, wherein the guide RNA comprises:
(a) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 13, wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 11;
(b) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 29, wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 27;
(c) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 47, wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 45;
(d) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 56, wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 54;
(e) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 3, wherein the RGN polypeptide comprises an amino acid sequence having at least 98% sequence identity to SEQ ID NO: 1;
(f) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 21, wherein the RGN polypeptide comprises an amino acid sequence having at least 98% sequence identity to SEQ ID NO: 19; or
(g) a tracrRNA comprising a nucleotide sequence having at least 95% sequence identity to SEQ ID NO: 38, wherein the RGN polypeptide comprises an amino acid sequence set forth as SEQ ID NO: 36.