Patent ID: 11913031
Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Field: Measurement (Instruments)
Classification: CPC C  G  B | IPC C

Claim 22:
23. The in vitro method of claim 22, wherein said exposing comprises:
a. flowing over said adherent cells in culture at least said first medium and said third medium;
b. decreasing the volumetric flow rate of said first medium while simultaneously increasing the volumetric flow rate of said third medium, said second medium or both so as to maintain a constant total volumetric flow rate;
c. flowing over said adherent cells at least said second medium and said third medium;
d. increasing the volumetric flow rate of said second medium while simultaneously decreasing the volumetric flow rate of said first medium, said third medium or both so as to maintain a constant total volumetric flow rate;
e. decreasing the volumetric flow rate of said second medium while simultaneously increasing the volumetric flow rate of said third medium, said first medium or both so as to maintain a constant total volumetric flow rate; and
f. repeating steps a-e with a periodicity of 24±4 hours.