Patent ID: 11866465
Assignee: JUNO THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 11:
12. The multimerized oligomeric particle reagent of claim 1, wherein the receptor-binding agent is a first receptor-binding agent, the streptavidin-binding peptide is a first streptavidin-binding peptide, and the multimerized oligomeric particle reagent comprises a second receptor-binding agent, wherein:
the second receptor-binding agent comprises a streptavidin-binding peptide that is reversibly bound to one or more binding sites of the streptavidin or streptavidin mutein molecules of the oligomer; and
the second receptor-binding agent binds to a second molecule on the surface of the target cell, wherein binding to the second molecule induces a second signal in the target cell.