Patent ID: 11866412
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 9:
10. A process for synthesizing the acridin-9-one derivative compounds of claim 1, the process comprising:
preparing a 2-((4-bromophenypamino)-5-fluoro-3-nitrobenzoic acid of the formula III:, , by reacting, , in the presence of K2CO3, wherein Y and W are each independently CH or N;
reacting the 2-((4-bromophenyl)amino)-5-fluoro-3-nitrobenzoic acid of the formula III with Eaton's reagent to obtain a 7-bromo-2-fluoro-4-nitroacridin-9(10H)-one of the formula IV:, reacting the 7-bromo-2-fluoro-4-nitroacridin-9(10H)-one of the formula IV first with SnCl2 in DMF, then with CH3l in the presence of DMF to obtain an acridine derivative of the formula V:, converting the acridine derivative of the formula V to produce the acridin-9-one compound of formula I.