Patent ID: 11912709
Assignee: UNIVERSITY OF MASSACHUSETTS
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 7:
8. The temozolomide compound of claim 1, wherein
X is —O— or —NH—;
n is 1;
L1 is a divalent C1-6 alkylene group; and
R1 is a sulfobetaine zwitterionic group having the structure A-B—C-L2-, wherein
A is a sulfonate group;
B is a divalent C1-6 alkylene group;
C is a divalent ammonium group; and
L2 is a divalent C1-6 alkylene group;

wherein L2 of the zwitterionic group is covalently bound to L1 through a thioether bond or a disulfide bond.