Patent ID: 11911762
Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
Field: Measurement (Instruments)
Classification: CPC B  G | IPC B  G

Claim 10:
11. A method comprising:
isolating target particles from other particles included in a biological fluid sample using a separation unit comprising nanoscale deterministic lateral displacement arrays formed on a microfluidic chip in fluid communication with an inlet bus formed around a perimeter of a first side of the nanoscale deterministic displacement arrays;
collecting, as a result of the isolating, the target particles in an outlet bus formed on a second side of the nanoscale deterministic displacement arrays opposite the first side; and
driving flow of a buffer fluid comprising the target particles from the outlet bus to a sensing element of the microfluidic chip configured to facilitate detecting presence of one or more biomarkers associated with the target particles, wherein the outlet bus surrounds the detection unit and supplies the particles of interest onto the sensing element.