Patent ID: 11857647
Assignee: JUBILANT DRAXIMAGE INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 6:
7. A reconstituted radiopharmaceutical composition according to claim 1, wherein the reconstituted radiopharmaceutical composition is prepared by a process comprising the steps of:
(a) preparing a first solution which comprises tetrofosmin disulfosalicylate;
(b) adding gentisic acid to the first solution;
(c) adding at least one or more reducing agent selected from the group consisting of stannous chloride dihydrate, stannous tartrate, stannous phosphate, stannous citrate or their pharmaceutically acceptable salts thereof to the first solution;
(d) adding at least one or more transchelator selected from gluconic acid, acetic acid, citric acid, tartaric acid, glucoheptonic acid, or phosphonic acid or their pharmaceutically acceptable salts thereof and combinations thereof; and sodium bicarbonate to the first solution;
(e) lyophilizing said first solution to form a lyophilate;
(f) preparing an aqueous solution of 99mTc pertechnetate; and
(g) mixing the lyophilate with the aqueous solution of 99mTc pertechnetate to form the reconstituted radiopharmaceutical composition.