Patent ID: 11859734
Assignee: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Field: Mechanical elements (Mechanical engineering)
Classification: CPC F | IPC F

Claim 22:
23. A method of forming a microfluidic device, comprising:
obtaining a first substrate having a first side, a second side opposite the first side, and an opening extending through the first substrate from the first side to the second side;
securing a resilient diaphragm to the second side of the first substrate to surround the opening of the first substrate;
securing an actuator to the first side of the first substrate to surround the opening of the first substrate and so the first substrate, the resilient diaphragm, and the actuator cooperate to form a gas-tight chamber;
obtaining a second substrate having a first side, a second side opposite the first side, and a channel formed in the second side, the channel having a first end and a second end;
securing the second substrate to the first substrate so the second side of the first substrate and the first side of the second substrate are in face-to-face contact and a least a portion of the resilient diaphragm is positioned between the first end of the channel and the second end of the channel; and
pressurizing the gas-tight chamber to expand the resilient diaphragm so at least a portion of the resilient diaphragm is disposed in the channel between the first end and the second to form a fluid-tight seal between the first end of the channel and the second end of the channel.