Patent ID: 11918565
Assignee: PACIRA PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 24:
25. A method of administering a sciatic nerve block in a popliteal fossa to reduce post-operative foot pain in a patient, the method comprising:
a) selecting an entry point of an injection needle in a leg of the patient;
b) advancing a needle tip of the injection needle within a region where the sciatic nerve splits into the peroneal and tibial nerves of the patient along a trajectory that extends between the entry point and the region where the sciatic nerve splits into the peroneal and tibial nerves;
c) piercing with the needle tip of the injection needle the sciatic nerve sheath in said region;
d) administering through the injection needle 133 mg of a multivesicular liposome pharmaceutical composition;
wherein the multivesicular liposome pharmaceutical composition comprises:
bupivacaine or a salt thereof;
phosphoric acid;
a lipid component comprising at least one amphipathic lipid and at least one neutral lipid lacking a hydrophilic head group; and,
optionally, a cholesterol and/or a plant sterol,
thereby administering a sciatic nerve block in the popliteal fossa to reduce post-operative foot pain in the patient.