Patent ID: 11884671
Assignee: CANCER RESEARCH TECHNOLOGY LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 9:
10. The compound of Formula (I), or a pharmaceutically acceptable salt thereof, as claimed in claim 1, wherein the compound is selected from the group consisting of:
9-(1-acetylpiperidin-4-yl)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-acetylpiperidin-4-yl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-acetylpiperidin-4-yl)-7-methyl-2-((7-methylquinazolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-acetylpiperidin-4-yl)-2-((2,7-dimethylquinoxalin-6-yl)amino)-7-methyl-7,9-dihydro-8H-purin-8-one;
9-(1-acetylpiperidin-4-yl)-2-((3,7-dimethylquinoxalin-6-yl)amino)-7-methyl-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
2-((4,7-dimethylquinolin-6-yl)amino)-9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxycyclohexyl)-2-((4-methoxy-7-methylquinolin-6-yl)amino)-7-methyl-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxycyclohexyl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-hydroxy-1-methylcyclohexyl)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
(S)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(tetrahydrofuran-3-yl)-7,9-dihydro-8H-purin-8-one;
(S)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-9-(tetrahydrofuran-3-yl)-7,9-dihydro-8H-purin-8-one;
(R)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(tetrahydrofuran-3-yl)-7,9-dihydro-8H-purin-8-one;
(R)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-9-(tetrahydrofuran-3-yl)-7,9-dihydro-8H-purin-8-one;
(R)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(tetrahydro-2H-pyran-3-yl)-7,9-dihydro-8H-purin-8-one;
(R)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-9-(tetrahydro-2H-pyran-3-yl)-7,9-dihydro-8H-purin-8-one;
(S)-7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(tetrahydro-2H-pyran-3-yl)-7,9-dihydro-8H-purin-8-one;
(S)-7-methyl-2-((7-methylquinoxalin-6-yl)amino)-9-(tetrahydro-2H-pyran-3-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinolin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinoxalin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinazolin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
2-((2,7-dimethylquinoxalin-6-yl)amino)-7-methyl-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
2-((3,7-dimethylquinoxalin-6-yl)amino)-7-methyl-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;
9-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinolin-6-yl)amino)-9-(oxetan-3-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinolin-6-yl)amino)-9-(piperidin-4-yl)-7,9-dihydro-8H-purin-8-one;
9-((3S,4R)-3-fluoropiperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1s,4s)-4-amino-4-methylcyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((1r,4r)-4-amino-4-methylcyclohexyl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
(R)-7-methyl-9-(1-methylpyrrolidin-3-yl)-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
(S)-7-methyl-9-(1-methylpyrrolidin-3-yl)-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylcinnolin-6-yl)amino)-9-(1-methylpiperidin-4-yl)-7,9-dihydro-8H-purin-8-one;
7-methyl-9-(1-methylpiperidin-4-yl)-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
7-methyl-9-(1-methylpiperidin-4-yl)-2-((7-methylquinoxalin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-((3S,4R)-3-fluoro-1-methylpiperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
7-methyl-2-((7-methylquinolin-6-yl)amino)-9-(1-(oxetan-3-yl)piperidin-4-yl)-7,9-dihydro-8H-purin-8-one;
9-(1-(2-hydroxyethyl)piperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-(2-methoxyethyl)piperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-ethylpiperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one;
9-(1-acetylpiperidin-4-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one; and
9-((3R,4R)-4-fluoropyrrolidin-3-yl)-7-methyl-2-((7-methylquinolin-6-yl)amino)-7,9-dihydro-8H-purin-8-one.