Patent ID: 11963786
Assignee: UNIVERSITY OF MIAMI
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A

Claim 8:
9. A system for determining cognitive impairment (CI) comprising:
a database including a quantification of retinal structure and retinal function of a plurality of eyes associated with a plurality of patients, the quantification providing a baseline cognitive impairment (CI) reference; and
at least one processor configured to
receive an electroretinogram (ERG) of a retina of a patient,
determine a measure of functionality of neurons in the retina based on the ERG,
receive a retinal image of the retina,
skeletonize the retinal image as a skeletonized retinal image,
determine a structural measure of the first retina based on
a generalized dimension spectrum and singularity spectrum of the skeletonized retinal image, and
a lacunarity parameter of the skeletonized retinal image,

compare the measure of functionality and the structural measure of the retina to the database, and
determine a level of cognitive impairment of the patient based on the comparing.