Patent ID: 11884733
Assignee: DRAGONFLY THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 7:
8. The protein according to claim 7, wherein:
the amino acid sequence of the first antibody constant region differs from the amino acid sequence of an IgG1 constant region by a Y349C substitution and wherein the amino acid sequence of the second antibody constant region differs from the amino acid sequence of an IgG1 constant region by an S354C substitution; and/or
the amino acid sequence of the first antibody constant region differs from the amino acid sequence of an IgG1 constant region by K360E and K409W substitutions and wherein the amino acid sequence of the second antibody constant region differs from the amino acid sequence of an IgG1 constant region by Q347R, D399V and F405T substitutions.