Patent ID: 11963750
Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Field: Medical technology (Instruments)
Classification: CPC A  G  Y | IPC A  G

Claim 23:
24. A method of detecting neutropenia in a subject, comprising:
acquiring a set of images, with an imaging device, of a capillary bed of a body portion of the subject;
generating a confidence value associated with an image of each capillary of the one or more of capillaries in the set of images;
detecting, without manual input, in one or more images of the set of images, one or more capillaries of the body portion of the subject, the one or more capillaries including those capillaries for which the confidence value, for each image in which that capillary is detected, exceeds a confidence threshold;
detecting a set of cellular events in the one or more capillaries; and
classifying the subject to a first classification type of a set of classification types, at least one classification type of the set of classification types associated with a diagnosis of neutropenia, the classifying based on:
an event count based on the set of cellular events detected in the one or more capillaries, each cellular event of the set of cellular events associated with passage of one or more types of white blood cells (WBCs) in a capillary of the one or more capillaries; and
the event count threshold which is associated with a minimum number of cellular events for classification of the subject to the first classification type.