Patent ID: 11940414
Assignee: ZOMEDICA BIOTECHNOLOGIES LLC
Field: Measurement (Instruments)
Classification: CPC G  H | IPC G  H

Claim 10:
11. A sensing device comprising:
a first sidewall and a second sidewall, wherein a fluid channel is defined between the first sidewall and the second sidewall;
a sensor having a surface defining at least a portion of the fluid channel;
an analyte capture ligand bound to the surface of the sensor;
a cover disposed over, and coupled to, the first and second sidewalls, wherein a surface of the cover defines at least a portion of the channel opposing the surface of the sensor; and
a crowding agent separately bound to a surface of the cover, the first sidewall, the second sidewall, or any combination thereof,
wherein the position and length of the crowding agent is sufficiently close to the surface of the bulk acoustic resonator for the crowding agent to slow kinetics of target analyte binding to the analyte capture ligand when a fluid sample composition comprising the target analyte is flowed through the channel and across the surface of the sensor, and
wherein the crowding agent does not specifically bind to the target analyte.