Patent ID: 11942187
Assignee: LIPOSCIENCE, INC.
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 8:
9. A system for obtaining data regarding lipoprotein constituents in a subject, comprising:
an NMR spectrometer for acquiring at least one composite NMR spectrum of an in vitro biosample comprising blood, plasma, or serum from a subject; and
at least one processor in communication with the NMR spectrometer, the at least one processor configured to determine, for a respective biosample using the acquired at least one composite NMR spectrum, concentrations of small and large HDL particle subclasses in the biosample and adjust at least one of the determined small and large HDL particle subclass concentrations based on a predetermined mathematical model that predicts risk of developing or having CHD, wherein the model comprises at least one weighting factor to adjust the concentration of the small HDL particle subclass, the concentration of the large HDL particle subclass, or the concentrations of both the small and large HDL particle subclasses.