Patent ID: 11932676
Assignee: KLOTHO THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 17:
18. The method of claim 13 further comprising:
measuring a concentration of soluble Klotho protein in a bodily fluid of the subject;
calculating a first dosage of the pharmaceutical composition sufficient to raise the concentration of soluble Klotho protein in the bodily fluid of the subject above a predetermined level and to maintain the concentration of soluble Klotho protein in the bodily fluid of the subject above the predetermined level for a predetermined period of time,
wherein administering the pharmaceutical composition comprises administering the first dosage of the pharmaceutical composition to the subject, wherein the step of administering the first dosage is sufficient to raise the concentration of soluble Klotho protein in the bodily fluid of the subject above the predetermined level and to maintain the concentration of soluble Klotho protein in the bodily fluid of the subject above the predetermined level for the predetermined period of time, wherein the predetermined period of time is at least 6 hours; and

administering one or more subsequent dosage(s) of the pharmaceutical composition to the subject, wherein the step of administering one or more subsequent dosage(s) is sufficient to maintain the concentration of soluble Klotho protein in the bodily fluid of the subject above the predetermined level for an extended period of time, wherein the extended period of time is optionally at least 24 hours.