Patent ID: 11970453
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 9:
10. A method of making the 2-ethoxy-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile compound of claim 1, the method comprising:
mixing cyclohexanone, 4-fluorobenzaldehyde, malononitrile, and sodium ethoxyethoxide in ethanol to obtain a reaction mixture;
refluxing the reaction mixture;
cooling the reaction mixture to room temperature and pouring the reaction mixture into crushed ice;
filtering, washing, and drying a formed precipitate;
recrystallizing a solid from ethanol; and
obtaining the 2-ethoxy-8-(4-fluorobenzylidene)-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile compound.