Patent ID: 11865112
Assignee: PURDUE PHARMA L.P.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 11:
12. A method of preparing a subject prior to entering a locale having a potentially toxic level of an opioid such that the subject is protected from experiencing an opioid overdose as a result of entering the locale, said preparation comprising administering to the subject prior to the subject entering the locale a parenteral formulation comprising a therapeutically effective amount of nalmefene or a pharmaceutically acceptable salt thereof and magnesium chloride at a concentration ranging from about 0.5% (w/v) to about 1% (w/v), wherein the formulation provides a mean time to maximum plasma concentration of nalmefene of about 2.0 hours or less post an intramuscular administration to a population of healthy subjects.