Patent ID: 11857604
Assignee: NH THERAGUIX
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 0:
1. A nanovector for the delivery of an active substance in a human being, wherein said nanovector comprises a nanoparticle on the surface of which the active substance is bonded by physisorption, said nanoparticle is a polysiloxane-based nanoparticle with a mean diameter of less than 10 nm, the active substance is chosen from organic molecules which have a molar mass of between 2% and 40% of the total molar mass of said nanoparticle, and said nanoparticle comprises:
a. polysiloxanes, with a weight ratio of silicon of at least 8% of the total weight of the nanoparticle,
b. a chelating agent grafted onto the nanoparticle, wherein the chelating agent which is grafted onto the nanoparticle is selected from DOTA, DTPA, EDTA, EGTA, BAPTA, NOTA, DOTAGA and DTPABA or a mixture thereof, and
c. optionally, a metal element, said metal element being complexed to the chelating agent.