Patent ID: 11904016
Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 21:
22. A method of treating a subject comprising, administering a stem cell mobilizing agent to the subject, harvesting hematopoietic stem cells from the subject, enriching the harvested stem cells for CCR2 positive (CCR2+) , CD34 positive (CD34+), or lineage negative (lin-) cells, administering to the subject the enriched harvested stem cells, and administering to the subject an immune checkpoint inhibitor, wherein the one or more immune checkpoint inhibitors are each an antagonist of cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), and/or B7 family inhibitory ligand B7-H3.