Patent ID: 11873527
Assignee: THE CHINESE UNIVERSITY OF HONG KONG
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C

Claim 10:
11. The method of claim 1, further comprising identifying one of the one or more differentially-methylated regions by:
obtaining methylation indexes of a plurality of sites for each of the plurality of cell lineages, including the particular cell lineage and the other cell lineages;
at each site of the plurality of sites, comparing the methylation indexes of the plurality of cell lineages;
identifying one or more sites of the plurality of sites that have a methylation index in the particular cell lineage that is:
below a first methylation threshold and methylation indexes in each of the other cell lineages that are above a second methylation threshold, or
above the first methylation threshold and methylation indexes in each of the other cell lineages that are below the second methylation threshold; and

identifying the one of the one or more differentially-methylated regions that contains the one or more sites.