Patent ID: 11969280
Assignee: CLEERLY, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  G  Y | IPC A  G

Claim 19:
20. A computer implemented method of quantifying ischemia for a subject based on non-invasive medical image analysis using the normalization device of claim 1, wherein the normalization device improves accuracy of the non-invasive medical image analysis, the method comprising:
accessing, by a computer system, a medical image of a coronary region of a subject, wherein the medical image of the coronary region of the subject is obtained non-invasively;
identifying, by the computer system, one or more segments of coronary arteries and one or more regions of plaque within the medical image of the coronary region of the subject;
quantifying, by the computer system, a proximal volume of a proximal section and a distal volume of a distal section along the one or more segments of coronary arteries, wherein the proximal section does not comprise the one or more regions of plaque, and wherein the distal section comprises at least one of the one or more regions of plaque;
accessing, by the computer system, an assumed velocity of blood flow at the proximal section;
quantifying, by the computer system, a velocity of blood flow at the distal section based at least in part on the assumed velocity of blood flow at the proximal section, the quantified proximal volume of the proximal section, and the distal volume of the distal section along the one or more segments of coronary arteries;
determining, by the computer system, a velocity time integral of blood flow at the distal section based at least in part on the quantified velocity of blood flow at the distal section; and
quantifying, by the computer system, ischemia along the one or more segments of coronary arteries based at least in part on the determined velocity time integral of blood flow at the distal section,
wherein the computer system comprises a computer processor and an electronic storage medium.