Patent ID: 11920174
Assignee: CUREVAC SE
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C  G

Claim 12:
13. The method of claim 12, wherein the homopolymeric element is a poly(A) stretch and wherein the length of the poly (A) stretch is determined by using formula 5.1:

lAm=n(A)/n(RNA)−[u(A)−lAe];, wherein lAm is the calculated average length of the poly(A) stretch, n(A) is the measured content of the nucleoside A in the sample, n(RNA) is the number of copies of the RNA molecules in the sample, u(A) is the number of nucleoside A in the expected sequence of the RNA molecules, and lAe is the expected average length of the poly(A) stretch in the RNA molecules.