Patent ID: 11883481
Assignee: ZOETIS SERVICES LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 13:
14. A recombinant Herpesvirus of Turkey (HVT) genome comprising:
a. an expression cassette inserted into the intergenic loci UL 35/UL 36 of the unique long region of the HVT genome comprising, in order: a nucleotide sequence for the human cytomegalovirus promoter comprising SEQ ID NO. 1, the nucleotide sequence coding for the Infectious Bursal Disease Virus VP2 protein comprising a nucleotide sequence comprising at least 80% sequence identity to the nucleotide sequences comprising either SEQ ID NO.5 or SEQ ID NO. 10, and the nucleotide sequence coding for the Bovine Growth Hormone (BGH) poly A tail comprising SEQ ID NO.6; and
b. an expression cassette inserted into the UL55/Gene 3 site of the unique long region of the HVT genome comprising, in order: the nucleotide sequence for the murine cytomegalovirus promoter comprising SEQ ID NO. 2; the nucleotide sequence coding for the Newcastle Disease Virus F protein comprising a nucleotide sequence comprising at least 80% sequence identity to the nucleotide sequence comprising SEQ ID NO. 3, and the nucleotide sequence coding for the SV40 poly A tail comprising SEQ ID NO. 12.