Patent ID: 11891449
Assignee: IMMUNEONCO BIOPHARMACEUTICALS (SHANGHAI) INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 10:
11. The recombinant fusion protein of claim 9, comprising
i) a CD47 binding peptide-linker-anti-CD24 heavy chain variable region-heavy chain constant region fragment having the amino acid sequence of SEQ ID NO: 18, and an anti-CD24 light chain variable region-light chain constant region fragment having the amino acid sequence of SEQ ID NO: 20;
ii) a CD47 binding peptide-linker-anti-CD24 heavy chain variable region-heavy chain constant region fragment having the amino acid sequence of SEQ ID NO: 18, and an anti-CD24 light chain variable region-light chain constant region fragment having the amino acid sequence of SEQ ID NO: 22;
iii) an anti-CD24 heavy chain variable region-heavy chain constant region fragment having the amino acid sequence of SEQ ID NO: 24, and a CD47 binding peptide-linker-anti-CD24 light chain variable region-light chain constant region fragment having the amino acid sequence of SEQ ID NO: 26; or
iv) an anti-CD24 heavy chain variable region-heavy chain constant region fragment having the amino acid sequence of SEQ ID NO: 28, and a CD47 binding peptide-linker-anti-CD24 light chain variable region-light chain constant region fragment having the amino acid sequence of SEQ ID NO: 30.