Patent ID: 11918996
Assignee: GENECAPTURE, INC.
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 12:
13. A system for sample homogenization, nucleic acid fragmentation, and nucleic acid detection, the system comprising:
an integrated cartridge comprising:
a main housing comprising a sample well and a detection chamber;
a generally cylindrical sonication container housing a plurality of inert beads and configured to receive a sample fluid, the sonication container coupled to the main housing at an entrance to the sonication container and protruding outwardly therefrom;
a fluidic path for directing a sample fluid from a sample well, to the sonication container, and to the detection chamber, the system further comprising;

a temperature sensor configured to monitor the temperature of the sonication container; and
a processor in communication with the temperature sensor, a cooling mechanism, and a heating mechanism;
wherein the processor is configured to monitor readings from the temperature sensor and execute computer readable instructions to cool the sonication container via the cooling mechanism if a reading from the temperature sensor falls above a predetermined value, and to heat the sonication container via the heating mechanism if a reading from the temperature sensor falls below a predetermined value.