Patent ID: 11897967
Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A chimeric antigen receptor (CAR) comprising
(a) an anti-MUC1* antibody fragment wherein the anti-MUC1* antibody fragment comprises a heavy chain variable region and a light chain variable region that has complementarity determining regions (CDRs) in the heavy chain variable region and the light chain variable region as follows:
CDR1 heavy chain SEQ ID NO: 123,
CDR1 light chain SEQ ID NO: 173,
CDR2 heavy chain SEQ ID NO: 127,
CDR2 light chain SEQ ID NO: 177,
CDR3 heavy chain SEQ ID NO: 131, and
CDR3 light chain SEQ ID NO: 181; and
(b) a T cell receptor co-stimulatory domain.