Patent ID: 11869186
Assignee: ELUCID BIOIMAGING INC.
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 14:
15. The method of claim 1, wherein simulating the therapeutic response for the combination of any two or more of the lipid lowering agent, the anti-inflammatory agent, and the anti-diabetic agent in the patient-specific systems biology model comprises:
determining a set of molecules known to be affected by the any one or more of the lipid-lowering agent, the anti-inflammatory agent, and the anti-diabetic agent;
defining a therapeutic effect molecule level for each molecule in the set of molecules based on one or more known mechanisms of action of any one or more of the lipid-lowering agent, the anti-inflammatory agent, and the anti-diabetic agent on the set of molecules; and
estimating a therapeutic effect molecule level for molecules represented in the patient-specific systems biology model other than in the set of molecules, based on a simulated effect of the defined therapeutic effect molecule levels of the set of molecules on one or more of the other molecules represented in the network.