Patent ID: 11964986
Assignee: REJUVERON TELOMERE THERAPEUTICS AG
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 23:
24. A method for preparing the compound of claim 1, the method comprising;
reacting a compound of formula II-a, in the presence of
i. a base and R1-LG or
ii. R1—B(OH)2 or R1—BF3M, a copper-salt, and an amine,

to obtain a compound of formula II-b, wherein
R1 is selected from the group consisting of a linear or branched C1 to C6 alkyl, a C3 to C5 cycloalkyl, a C1-C3-alkyl-C3-C5-cycloalkyl, and a cyclic ether comprising 4 to 5 ring atoms,
wherein said C1 to C6 linear or branched alkyl is optionally substituted with one or more substituents selected from the group consisting of fluoro, chloro, hydroxy and C1 to C3 alkoxy,
wherein said C3 to C5 cycloalkyl and said C1-C3-alkyl-C3-C5-cycloalkyl may optionally be substituted with one or more substituents selected from the group consisting of fluoro, chloro, C1 to C3 alkyl, hydroxy and C1 to C3 alkoxy, and
wherein said cyclic ether comprising 4 to 5 ring atoms is optionally substituted with one or more substituents selected from the group consisting of fluoro, chloro, C1 to C3 alkyl, hydroxy and C1 to C3 alkoxy;

R2, R3, R4 and R5 in the formulae II-a and II-b have the same definition as in claim 1;
LG is a leaving group; and
M is an alkali metal.