Patent ID: 11932595
Assignee: KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY, TEIKYO UNIVERSITY AND THE UNIVERSITY OF TOKYO
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of formula (I):, or a stereoisomer, mixture of stereoisomers, and/or a pharmaceutically acceptable salt thereof,
wherein
the double bond from a to b is in the E-configuration or Z-configuration;
R1 is hydrogen;, , where Ra and Rb together with the carbon to which they are attached form an unsubstituted C5-C7-cycloalkyl group; —CH2—S-(heteroaryl); —CH2-(1,3-dioxo-isoindolin-2-yl);, , (ortho-carboranyl); —CH2—NH-(phenyl); or, R2a, R2b, R3, R3a, R3b, R4, R4a, and R4b are independently selected from hydrogen and halo;
one of X and Y is CR5 and the other is CH; or one of X and Y is CR5 and the other is N;
R5 is hydrogen; C1-C6-alkyl; hydroxy-C1-C6-alkyl; aryl optionally substituted with 1, 2, or 3 R5a groups; or 5- or 6-membered heteroaryl optionally substituted with 1, 2, or 3 R5a groups;
each R5a is independently hydrogen, alkyl, haloalkyl, or halo; and
wherein each phenyl and heteroaryl group are independently optionally substituted with 1, 2, 3, 4, or 5 groups independently selected from the group consisting of halogen, halo-C1-4 alkyl, —S-(halo-C1-4 alkyl), C1-4 alkoxy, halo-C1-4 alkoxy, nitro, cyano, and C1-4 alkoxycarbonyl; and
provided that the compound is not, or a stereoisomer, mixture of stereoisomers, and/or a pharmaceutically acceptable salt thereof.