Patent ID: 11890302
Assignee: TC BIOPHARM LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 4:
5. The gamma delta T cell of claim 1 wherein:
(a) the one or more Fcγ Receptor intracellular signalling domains comprises at least one CD32a or CD32c or CD 64 signalling domain, such that binding of antigen to the antigen binding domain of the CAR causes signalling by the intracellular signalling domain of the CAR;
(b) the CD32a or CD32c signalling domains have a sequence identity of at least 95% to SEQ ID NO 2 or SEQ ID NO: 3; or
(c) the CAR comprises the amino acid sequence of SEQ ID NO: 6 or SEQ ID NO:7.