Patent ID: 11939319
Assignee: UCB PHARMA GMBH
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 16:
17. A compound according to claim 1 and having Formula VI:, wherein
n is 0, 1, 2 or 3,
X3 is CH or N,
R2 is hydrogen or fluoro,
R4 is hydrogen or fluoro,
R5 is hydrogen or halogen,
X2 is N or C(R12),
R8 is selected from hydrogen, halogen, methoxy, ethoxy, fluoromethoxy and fluoroethoxy,
R10 is selected from hydrogen, cyano, halogen, C3-5 cycloalkyl, C3-5 cycloalkyloxy, C3-5 cycloalkylmethoxy, C1-4 alkoxy, and C1-4 alkyl, wherein each cycloalkyl, cycloalkyloxy, alkyl and alkoxy can be substituted with one or more substituent selected from halogen, C1-3 alkoxy, fluoro(C1-3)alkoxy and cyano,
R11 is selected from hydrogen, fluoro and methoxy,
R12 is selected from hydrogen, methoxy and halogen,
R13, in each occurrence, is independently selected from halogen, cyano, hydroxy, methyl, methoxy, fluoromethyl and fluoromethoxy,
or a pharmaceutically acceptable salt, solvate, isotope or co-crystal thereof.