Patent ID: 11878993
Assignee: SINGULAR GENOMICS SYSTEMS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A nucleic acid molecule comprising a nucleotide, wherein said nucleotide comprises (i) a cleavable moiety covalently bound to the 3′ oxygen of said nucleotide, said cleavable moiety having the formula -L1P-S—S—R6P (I); wherein,
L1P is a substituted methylene, wherein L1P is substituted with a substituted or unsubstituted alkyl, or a substituted or unsubstituted heteroalkyl;
R6P is unsubstituted C1-C4 alkyl; and
(ii) a detectable moiety attached to said nucleotide via a covalent linker, wherein said covalent linker comprises, wherein,
R102 is unsubstituted C1-C4 alkyl.