Patent ID: 11963818
Assignee: UNIVERSITA' DEGLI STUDI DI ROMA LA SAPIENZA
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 6:
7. The method according to claim 1, wherein the at least one cardiac cycle comprises at least one basal cardiac cycle and at least one papaverine injection cardiac cycle; wherein the CPRI relationship between the second area (Apost) and the first area (Apre) define a basal current peripheral resistance index (CPRIBase) that is associated the at least one basal cardiac cycle; wherein the method further comprises:
obtaining a time series indicating a blood velocity, or velocity signal, in said at least one sample volume and in the at least one papaverine injection cardiac cycle, characterized in that it comprises the following steps:
calculating a third area equal to an area subtended by the velocity signal between a sample relating to an instant of systole start of the at least one papaverine injection cardiac cycle and a sample relating to an instant of systolic peak of the at least one papaverine injection cardiac cycle;
calculating a fourth area equal to an area subtended by the velocity signal between a sample relating to an instant of diastole end of the at least one papaverine injection cardiac cycle and the sample relating to the instant of systolic peak of the at least one papaverine injection cardiac cycle;
calculating a current peripheral resistance index after injection of papaverine (CPRIPapaverine) relationship between the fourth area and the third area according to the following formula:, C
   ⁢
   P
   ⁢
   R
   ⁢
   
    I
    Papaverine
   
  
  =
  
   
    Fourth
    ⁢
       
    Area
   
   
    Third
    ⁢
       
    Area
   
  
 

calculating a predicted peripheral resistance index (PPRI) relationship between the CPRIBase and the CPRIPapaverine according to the following formula:, P
   ⁢
   P
   ⁢
   R
   ⁢
   I
  
  =
  
   
    C
    ⁢
    P
    ⁢
    R
    ⁢
    
     I
     
      B
      ⁢
      a
      ⁢
      s
      ⁢
      e
     
    
   
   
    C
    ⁢
    P
    ⁢
    R
    ⁢
    
     I
     Papaverine