Patent ID: 11925647
Assignee: HMI MEDICAL INNOVATIONS, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G | IPC A  C  G

Claim 0:
1. A method of testing a compound, the method comprising:
a) incubating a test cell which expresses a theramutein with a compound, the theramutein being capable of producing a detectable phenoresponse of the test cell;
b) incubating a control cell which expresses a prototheramutein corresponding to the theramutein with a known modulator of the prototheramutein, the prototheramutein being capable of producing the phenoresponse in the control cell;
c) comparing the phenoresponse of the control cell to the known modulator of the prototheramutein to the phenoresponse of the test cell to the compound; and
d) determining that the compound is a modulator of the theramutein when the phenoresponse of the test cell is modulated to at least the same degree as the phenoresponse of the control cell is modulated by the known modulator of the prototheramutein.