Patent ID: 11897880
Assignee: JANSSEN PHARMACEUTICA NV
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 6:
7. The compound of claim 5, wherein
R1 is selected from the group consisting of hydrogen, and methyl;
R2 is hydrogen and R3 is cyclopropyl-methyl-;
alternatively, R2 and R3 are taken together with the carbon atoms to which they are bound to form;, R4 is selected from the group consisting of hydrogen and fluoro;
R5 is selected from the group consisting of 4-(methoxy-carbonyl-amino)-phenyl, 2-fluoro-6-amino-pyridin-3-yl, 2-chloro-6-amino-pyridin-3-yl, 2-chloro-6-amino-pyridin-4-yl, 2-fluoro-6-amino-pyridin-4-yl, indol-5-yl, indazol-5-yl, benzimidazol-5-yl, benzothiazol-5-yl, 2-methyl-benzothiazol-5-yl, benzo[1,2,3]thiadiazol-5-yl, and imidazo[1,2-a]pyridin-7-yl;
a is an integer from 1 to 2;
each R6 is independently selected from the group consisting of 11-chloro and 12-fluoro;
R7 is hydrogen, and R8 and R9 are the same and selected from the group consisting of hydrogen, and methyl;
alternatively, R7 is hydrogen, and R8 and R9 are taken together with the carbon atom to which they are bound to form a ring structure selected from the group consisting of cycloprop-1,1-diyl, cyclobut-1,1-diyl and cyclopent-1,1-diyl;
or a pharmaceutically acceptable salt thereof.