Patent ID: 11877991
Assignee: MURRAY AND POOLE ENTERPRISES LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 9:
10. A method for inhibiting, delaying, or reducing tumor growth or metastases or both tumor growth and metastases in a subject diagnosed with or suffering from cancer, comprising administering to the subject a sustained release formulation comprising a homogeneous mixture of:
(a) between 0.1 mg to 0.60 mg of colchicine or a pharmaceutically acceptable salt thereof;
(b) a binder, wherein the binder is hydroxypropyl methylcellulose (HPMC) 6 mPa·s;
(c) a retarding agent, wherein the retarding agent is a spray agglomerated blend of equal parts by weight of HPMC with a viscosity grade of 4000 mPa·s and lactose monohydrate; and
(d) at least one pharmaceutically acceptable excipient,
wherein the sustained release formulation is a tablet,
and an effective amount of at least one other immune modulating therapy.