Patent ID: 11918686
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 14:
15. A composition comprising a plurality of drug delivery carriers, each drug delivery carrier comprising:
a silica body having a plurality of pores suitable to receive a therapeutic agent therein, and having a surface;
an intact lipid bilayer coating the surface and encapsulating the silica body and stably sealing the plurality of pores, wherein the encapsulating is performed without lipid phase exchange and without contacting a preformed liposome with the silica body;
a first therapeutic agent within the pores of the silica body, wherein the first therapeutic agent comprises gemcitabine; and
a second therapeutic agent disposed in the lipid bilayer, wherein the second therapeutic agent comprises paclitaxel.