Patent ID: 11940450
Assignee: UNIVERSITY OF CONNECTICUT
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method for treating ureteropelvic junction obstruction (UPJO) in a subject, wherein the subject is a human child, comprising:
(a) detecting in a urine sample from the subject one or more proteins selected from the group consisting of Immunoglobulin superfamily containing leucine-rich repeat protein (ISLR); Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT); Prostaglandin reductase 1 (PTGR1); Vascular cell adhesion protein 1 (VCAM1); and Ficolin-2 (FCN2);
(b) comparing an amount of the one or more proteins in the urine sample to a standard;
wherein the subject has an increase in the amount of at least one of the one or more proteins in the urine sample above the standard, diagnosing the subject as having UPJO; and
(c) treating the subject with surgery, endopyelotomy, laparoscopic pyeloplasty, and/or placement of a stent.