Patent ID: 11944967
Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC B  G | IPC B  G

Claim 16:
17. A method for separating sub-micrometer sized bioparticles, the method comprising:
depositing a fluidic sample in a microfluidic channel, wherein a plurality of micro-posts are disposed within the microfluidic channel; and
applying an electric field gradient to the fluidic sample to induce transport of sub-micrometer sized bioparticles in the fluidic sample by
applying a first waveform to the fluidic sample in the microfluidic channel, wherein the first waveform is a square wave having an amplitude, a frequency, and a DC offset voltage, and
applying a second waveform superimposed on the first waveform only during one selected from a group consisting of a high period of the first waveform and a low period of the first waveform, wherein the second waveform is a sinusoidal wave with a higher frequency than the first waveform, and wherein application of the second waveform superimposed on the first waveform causes the sub-micrometer sized bioparticles to separate by size.