Patent ID: 11903925
Assignee: REPOCEUTICALS A/S
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method for the treatment of lung damage due to chest irradiation, said method comprising:
providing a composition comprising a micronized powder, which comprises melatonin, to a patient, wherein:
said patient is selected as having a primary or secondary cancer of the chest and is to receive external beam radiotherapy with a total radiation dose in the range of 2-70 GY;
said selected patient receives said composition via intratracheal, intrabronchial, or bronchoalveolar inhalation no more than 15 minutes before each dose of said radiotherapy;
said micronized powder comprises a sugar excipient and particles having an aerodynamic diameter of 2 μm to 5 μm; and
the dosage of melatonin administered is in the range of 5-20 mg per inhalation.