Patent ID: 11875983
Assignee: PURDUE RESEARCH FOUNDATION
Field: Electrical machinery, apparatus, energy (Electrical engineering)
Classification: CPC H  C  Y | IPC C  H

Claim 10:
11. A method for extracting an analyte from a sample in a manner that the analyte is ready for ionization, the method comprising:
introducing a solvent into a capillary;
introducing the capillary into a vessel comprising a sample such that a portion of the sample is introduced into the capillary, wherein the sample comprises an analyte of interest that does not readily ionize;
introducing an additional liquid into the capillary, the additional liquid comprising a reactant molecule that is capable of reacting with the analyte of interest to form a reaction product that is readily ionizable; and
moving the sample, the additional liquid, and the solvent within the capillary to induce circulation within the sample and the solvent and the additional liquid, thereby causing the analyte to react with the reactant molecule to form the reaction product that is readily ionizable and causing the reaction product to be extracted from the sample into the solvent.