Patent ID: 11932875
Assignee: THE AEROSPACE CORPORATION
Field: Medical technology (Instruments)
Classification: CPC A  C  B | IPC B  C

Claim 0:
1. A method of creating a modified material substrate configured for stimulating and controlling stem cell differentiation, said method comprising:
providing a material substrate configured for medical use, wherein the material substrate comprises at least one surface and interior bulk location available for modification, and
treating the material substrate with a plurality of pulsed light beams to obtain a modified material substrate comprising at least one modified surface and at least one modified interior location, wherein the plurality of pulsed light beams extend into the interior bulk location to cause a laser-scripted induction modification including at least one of a magnetic feature, a ferroelectric feature, or a piezoelectric feature;
wherein the at least one modified surface or interior location comprises a biomimetic architecture comprising surface and bulk features, properties, and textures configured to accelerate and control stem cell differentiation when the modified material substrate is contacted with stem cells, and wherein the laser-scripted induction modification exerts an influence during stem cell differentiation through the at least one modified surface of the material substrate.