Patent ID: 11918661
Assignee: PURDUE RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A nano-droplet composition comprising a fluorocarbon core and a polymeric shell, wherein:
the fluorocarbon core and the polymeric shell form a micelle with a size range of 10-1000 nm;
the fluorocarbon core comprises at least one fluorocarbon compound with a formula of CnF2n+2 and n is 5-10;
the polymeric shell comprises a biocompatible polymic material, wherein the biocompatible polymeric material comprises bovine serum albumin and is modified with various ligands to turn the nano-droplet into a multi-functional agent suitable for targeted diagnostics and therapy;
the fluorocarbon compound is substantial in liquid form; and
the nano-droplet composition has a temperature profile such that the nano-droplet composition has a temperature range of 20-60° C. throughout a temperature modulation process, and has a temperature of about 37° C. prior to administration to a human, animal, biological cell, or tissue subject.