Patent ID: 11898984
Assignee: OXFORD NANOPORE TECHNOLOGIES PLC
Field: Measurement (Instruments)
Classification: CPC G  B  C | IPC B  C  G

Claim 0:
1. A device for polymer sequencing comprising:
an array of nanopores,
above the array of nanopores, in fluidic contact with the array of nanopores, an upper fluidic region comprising an upper electrode, the upper fluidic region comprising polymer molecules,
below the array of nanopores, an array of discrete fluidic regions, each discrete fluidic region in fluidic contact with a nanopore of the array of nanopores, and each discrete fluidic region comprising a lower electrode and internal surfaces, wherein there is no direct fluidic contact between the discrete fluidic regions,
a pre-treatment coating of a hydrophobic fluid applied to the internal surfaces of each discrete fluidic region, wherein the hydrophobic fluid does not cover the lower electrode,
an array of layers of amphiphilic molecules, wherein each layer of amphiphilic molecules separates one of the discrete fluidic regions from the upper fluidic region,
wherein each nanopore of the array of nanopores is disposed within one of the layers of amphiphilic molecules, and
an array of electronic circuits below the array of discrete fluidic regions, each electronic circuit comprising an amplifier in electrical contact with the fluidic region above it.