Patent ID: 11903995
Assignee: L'OREAL
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 4:
5. The method according to claim 1, in which the at least one derivative of arthrofactin A is chosen from the group consisting of arthrofactin B, arthrofactin C, arthrofactin D and mixtures thereof,
arthrofactin B being of formula (III) below:

R-D-Leu1-D-Asp2-D-allo-Thr3-D-Leu4-D-Leu5-D-Ser6-L-Leu7-D-Ser8-L-Ile9-L-Ile10-L-Glu11  (III),

in which
the hydroxyl group of the D-allo-Thr3 amino acid residue forms an ester bond with the C-terminal carboxyl group of the L-Glu11 amino acid residue, and

arthrofactin C being of formula (IV) below:

R2-D-Leu1-D-Asp2-D-allo-Thr3-D-Leu4-D-Leu5-D-Ser6-L-Leu7-D-Ser8-L-Ile9-L-Ile10-L-Asp11  (IV),

in which
the hydroxyl group of the D-allo-Thr3 amino acid residue forms an ester bond with the C-terminal carboxyl group of the L-Asp11 amino acid residue, and
R2 represents the group of formula (IV′) below:, where R2′ is an alkyl chain of 9 carbon atoms comprising exactly one unsaturation;

arthrofactin D being of formula (V) below:

R3-D-Leu1-D-Asp2-D-allo-Thr3-D-Leu4-D-Leu5-D-Ser6-L-Leu7-D-Ser8-L-Ile9-L-Ile10-L-Asp11  (V),

in which
the hydroxyl group of the D-allo-Thr3 amino acid residue forms an ester bond with the C-terminal carboxyl group of the L-Asp11 amino acid residue, and
R3 represents the group of formula (V′) below:, where R3′ is a saturated alkyl chain of 9 carbon atoms.