Patent ID: 11932909
Assignee: SELF-SCREEN B.V.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 10:
11. The kit of claim 1, said kit further comprising means for the specific amplification of a bisulfite modified sequence of at least one of ZIC1 and ZNF-582 and detection of at least one of ZIC1 and ZNF-582, wherein said means comprises one or more of:
a probe and primers for methylation specific PCR, wherein said probe and primers are specific for a bisulfite modified sequence of the ZNF-582 nucleotide sequence of SEQ ID NO:25 and that target a CpG rich sequence in said bisulfite modified sequence, wherein said probe and/or primers comprise a detectable label,
a probe and primers for methylation specific PCR, wherein said probe and primers are specific for a bisulfite modified sequence of the ZIC1 nucleotide sequence of SEQ ID NO:26 and that target a CpG rich sequence in said bisulfite modified sequence, wherein said probe and/or primers comprise a detectable label.