Patent ID: 11878312
Assignee: PNEUMATIC SCALE CORPORATION
Field: Chemical engineering (Chemistry)
Classification: CPC B  C | IPC B

Claim 27:
28. Apparatus comprising:
a single use structure configured for use in a centrifuge system including a multi use rotatable centrifuge bowl, wherein the single use structure is configured to be releasably positioned in the bowl and to separate within an interior area of the single use structure, cells in a cell culture batch material into concentrate and centrate,
the single use structure including:
a first disc shape portion at a first axial end,
a second axial end axially disposed of the first axial end,
an annular radially extending core coaxially arranged with the first disc shape portion and positioned axially intermediate of the first disc shape portion and the second axial end,
an outer wall, wherein the outer wall
is in fluid tight operative relation with the first disc shape portion,
extends in surrounding relation of at least a portion of the core,
bounds a separation chamber that extends radially between the core and the outer wall,

an axially extending central tube, wherein the central tube includes an inlet opening within the interior area, wherein the central tube is configured to pass cells therethrough,
an axially extending centrate discharge tube coaxial with and radially outward of the central tube,
a centrate centripetal pump, wherein the centrate centripetal pump is disposed coaxially about the central tube and is in fluid communication with the centrate discharge tube,
wherein the centrate centripetal pump is positioned in the interior area in a centrate centripetal pump chamber, wherein the centrate centripetal pump chamber is in fluid communication with the separation chamber,
wherein during rotation of the single use structure with the bowl, the first disc shape portion and the outer wall rotate relative to the centrate centripetal pump.