Patent ID: 11970502
Assignee: ENANTA PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A compound represented by Formula (III), or a pharmaceutically acceptable salt thereof:, wherein
m is 1;
n is 1;
X is selected from the group consisting of —CN, —C(O)C(O)NR13R14, and —C≡R13;

R1 and R2 are each independently hydrogen or C1-C6-alkyl;
R3 and R4 are each independently hydrogen or C1-C4-alkyl;
Z is —CR21R23-, or Z and the oxygen atom of the carbonyl group are taken together with the carbon atom to which they are attached to form an optionally substituted heteroaryl;
R21 is selected from the group consisting of hydrogen, halogen, optionally substituted —C1-C6 alkyl, and optionally substituted —C3-C8 cycloalkyl;
R23 is selected from the group consisting of hydrogen, halogen, —OH, —OR15, —OC(O)R15, —OC(O)OR15, —OC(O)NR13R14, —NR13R18, —N3, —CN, optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C2-C8 alkynyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, and optionally substituted heteroarylalkyl;
R13 and R14 are independently selected from the group consisting of hydrogen, optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C2-C8 alkynyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl; alternatively R13 and R14 are taken together with the nitrogen atom to which they are attached to form an optionally substituted 3- to 8-membered heterocyclic ring;
R15 is selected from the group consisting of optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C2-C8 alkynyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, and optionally substituted heteroarylalkyl;
R18 is selected from the group consisting of hydrogen, optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C2-C8 alkynyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, —C(O)R15, —C(O)OR15, —C(O)NR13R14, —C(O)C(O)NR13R14, —S(O)2R15, and —S(O)2NR13R14; and
R31 and R32 are both hydrogen.