Patent ID: 11866428
Assignee: ASTEX THERAPEUTICS LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 19:
20. The protected form of formula (I) as defined in claim 11, wherein the amine group is protected as:
(a) an amide (—NRCO—R) or a carbamate (—NRCO—OR) selected from the group consisting of: a methyl amide (—NHCO—CH3); a benzyl carbamate (—NHCO—OCH2C6H5, —NH-Cbz or NH—Z); a t-butyl carbamate (—NHCO—OC(CH3)3, —NH-Boc); a 2-biphenyl-2-propyl carbamate (—NHCO—OC(CH3)2C6H4C6H5, —NH-Bpoc), a 9-fluorenylmethyl carbamate (—NH—Fmoc), a 6-nitroveratryl carbamate (—NH—Nvoc), a 2-trimethylsilylethyl carbamate (—NH—Teoc), a 2,2,2-trichloroethyl carbamate (—NH-Troc), an allyl carbamate (—NH—Alloc), and a 2(-phenylsulfonyl)ethyl carbamate (—NH—Psec); or
(b) an amine protecting group selected from the group consisting of toluenesulfonyl (tosyl) and methanesulfonyl (mesyl) groups, benzyl groups, and a tert-butyloxycarbonyl (tBoc) group.