Patent ID: 11912709
Assignee: UNIVERSITY OF MASSACHUSETTS
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 6:
7. The temozolomide compound of claim 1, wherein
X is —O— or —NH—;
n is 1;
L1 is a divalent di(C2-12 alkylene) disulfide group, C2-12 alkylene ester group, C6-20 arylene group, C1-20 alkylene oxide group, or C1-12 alkylene sulfide group; and
R1 is a phosphorylcholine zwitterionic group having the structure A-B—C—, wherein
A is an ammonium group of the formula —N(R7)3, wherein R7 is a C1-6 alkyl group;
B is a divalent C1-6 alkylene group; and
C is a divalent phosphate group.