Patent ID: 11965202
Assignee: GIVAUDAN SA
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A method of making a compound of formula (I), wherein the method comprises the step of:
contacting a compound of formula (II) with a squalene-hopene cyclase (SHC),, to produce a compound of formula (I), wherein Y of formula (I) is selected from CHOH and C═O,
wherein R1, R2 and R3 are the same for formula (I) and formula (II) and the dotted line of formula (II) represents, together with the carbon-carbon bond, either a double bond or a triple bond,
wherein R1 and R2 are independently selected from hydrogen, alkyl and cycloalkyl,
wherein R3 is hydrogen or alkyl, and
wherein the SHC is variant 215G2 of Alicyclobacillus acidocaldarius SHC.