Patent ID: 11911359
Assignee: PDS BIOTECHNOLOGY CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 14:
15. A pharmaceutical formulation comprising a liposome together with at least one disease-associated antigen and a non-ionic buffer,
wherein the liposome comprises one or more cationic lipids,
wherein the one or more cationic lipids is a quaternary cationic lipid,
wherein the one or more cationic lipids is in an amount sufficient to both activate the ERK or p38 components of the MAP kinase signaling pathway and to induce the production of reactive oxygen species by at least 10% of immune cells in the lymph nodes, and
wherein the pharmaceutical formulation is free of phosphate buffered saline (PBS);
wherein the disease-associated antigen is a protein or peptide.