Patent ID: 11969456
Assignee: ABIONYX PHARMA SA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. An Apolipoprotein A-I (“ApoA-I”) formulation comprising: (a) an ApoA-I protein comprising the amino acid sequence of amino acids 25 to 267 of SEQ ID NO: 1, (b) sphingomyelin, and (c) 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] (“DPPG”) or a salt thereof, wherein:
(a) the ApoA-I, the sphingomyelin, and the DPPG or the salt thereof are in the form of lipoprotein complexes;
(b) the sphingomyelin and the DPPG or the salt thereof are present in a 97:3 weight:weight ratio; and
(c) the ApoA-I, the sphingomyelin and the DPPG or the salt thereof are present in a 1:2.7 ratio of weight ApoA-I:weight sphingomyelin and DPPG or salt thereof.