Patent ID: 11965165
Assignee: INTELLIA THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 17:
18. The method of claim 1, wherein
a. the subject has ATTR;
b. the subject has a family history of ATTR;
c. the subject has familial amyloid polyneuropathy;
d. the subject has only or predominantly nerve symptoms of ATTR;
e. the subject has familial amyloid cardiomyopathy;
f. the subject has only or predominantly cardiac symptoms of ATTR;
g. the subject expresses TTR having a V30 mutation;
h. wherein the subject expresses TTR having a T60 mutation;
i. wherein the subject expresses TTR having a V122 mutation;
j. wherein the subject expresses wild-type TTR;
k. wherein the subject does not express TTR having a V30, T60, or V122 mutation; or
l. wherein the subject does not express TTR having a pathological mutation.