Patent ID: 11866430
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 2:
3. The compound according to claim 1 or a salt thereof, wherein:
R1 is H, Cl, Br, —CN, C1-2 alkyl, —CH═CH2, —OCH3, —C(O)OH, —C(O)OCH3, —C(O)N(CH3)2, —NH2, or —NHC(O)OC(CH3)3;
R2 is —CH3, —CH2CH3, —CH2CH2CH3, —CH2CH2CH2CH3, —CH2CN, —CH2CH2CH2CN, —CH2CH2CF3, —CH2CH═CH2, —CH2CH2CH═CF2, —CH2C≡CH, —CH2CH2OCH3, —CH2CH2CH2OCH3, —CH2CH2CH2OCH2CH2OCH3, —CH2CH2CH2C(O)CH3, —CH2C(O)OCH2CH3, —CH2(cyclopropyl), or —CH2CH2(dioxanyl);
R3 is H, F, Cl, Br, —CN, —CH3, —CF3, —NO2, —C(O)OCH2CH3, or —C(O)CF3;
R4 is:
(a) 2,3-dihydro-1H-indenyl substituted with 1 to 2 substituents independently selected from F, —OH, —OCH3, and —OCH2CH═CH2; or
(b) —CH2Ry, —C(CH3)2Ry, —CHRxRy, —CH2CH(OH)Rx, —CH(CH3)(CH2CH2OCH3), or cyclopropyl substituted with fluorophenyl;
Rx is C1-2 alkyl, —CH(CH3)2, —C(CH3)3, —CH2C(CH3)3, —CH2OH, —CH2NH2, cyclopropyl, cyclobutyl, cyclohexyl, or phenyl substituted with zero to 2 substituents independently selected from F, Cl, —OH, and —OCH3; and
Ry is 1,3-benzodiazolyl, indazolyl, indolyl, ethyl indolyl, indolinyl, naphthalenyl, hydroxynaphthalenyl, oxoindolinyl, pyridinyl, methoxypyridinyl, pyrimidinyl, or phenyl substituted with zero to 3 substituents independently selected from F, Cl, Br, —OH, —CN, —CH3, —C(CH3)3, —CHF2, —CF3, —OCH3, —OCF3, —OCH2CH═CH2, —OCH2C≡CH, —OCH2(cyanopyridinyl), —NH2, —NHS(O)2CH3, —N(CH3)(CH2CH3), —NHC(O)CH3, —NHC(O)O(C(CH3)3), —NHC(O)(phenyl), —NHC(O)NH(phenyl), and phenyl.