Patent ID: 11905292
Assignee: INCYTE CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 62:
63. The process of claim 62, wherein the salt of formula 2d is prepared by a process comprising:
(a) reacting a compound of formula 2P:, , with MeMgBr in the presence of a Grignard catalyst to form a compound of formula 1aP:, (b) deprotecting the compound of formula 1aP to form a compound of formula 1a:, or a salt thereof; and
(c) reacting the compound of formula 1a, or the salt thereof, with a Vilsmeier reagent formed from dimethylformamide and a chlorinating agent to form the salt of formula 2d;
wherein P1 is an amino protecting group.