Patent ID: 11918785
Assignee: REGENERON PHARMACEUTICALS, INC.
Field: Medical technology (Instruments)
Classification: CPC A  B | IPC A  B

Claim 0:
1. A method of preparing a drug product, comprising:
introducing a volume of a formulated drug substance into a primary packaging component, wherein the volume of the formulated drug substance is greater than a nominal volume of the primary packaging component; and
stoppering the primary packaging component at a stopper position that is distal from a proximal end of the primary packaging component,
wherein stoppering the primary packaging component includes determining the stopper position, and determining the stopper position includes determining a distance below a flange of the primary packaging component that restricts a plunger rod, connected to the stopper, from tilting to deform the stopper to an extent that compromises a seal formed by the stopper.