Patent ID: 11931328
Assignee: AMNEAL PHARMACEUTICALS, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 14:
15. A method of making an immediate release pharmaceutical stick pack composition comprising an active ingredient comprising 4-amino-3-(4-chlorophenyl) butanoic acid) (“baclofen”) or a pharmaceutically acceptable salt thereof; poly(butyl methacrylate-co-(2-dimethylaminoethyl) methacrylate-co-methyl methacrylate) (stabilizer); and at least one excipient selected from the group consisting of xylitol, crospovidone, hypromellose, mannitol, saccharin sodium, and mixtures thereof; the method comprising:
a) dry blending the active ingredient, the stabilizer, and the at least one excipient to obtain a dry blend; and wet granulating the dry blend to obtain active granules;
b) dry blending the stabilizer, and the at least one excipient to obtain a dry blend; and wet granulating the dry blend to obtain placebo granules;
c) mixing the active granules, the placebo granules, colloidal silicon dioxide, calcium stearate, a flavoring agent and talc in a mixer to obtain a final blend; and
d) filling the final blend in one or more stick packs.