Patent ID: 11883367
Assignee: JANSSEN PHARMACEUTICA NV
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 1:
2. The compound according to claim 1, wherein
Ar is optionally substituted with one, two, three or four substituents each independently selected from the group consisting of halo, —OH, —NH2, —NH—C1-4alkyl, —N(C1-4alkyl)2, cyano, —CF3, —C(═O)—NH—C1-4alkyl, —C(═O)—C1-4alkyl, C1-4alkyloxy, and C1-4alkyl optionally substituted with one —NR10aR10b;
Het represents a bicyclic aromatic heterocyclic ring system selected from the group consisting of (a-1), (a-2) and (a-3):, R3a, R3b and R3c each independently represent hydrogen, halo, —NR7aR7b, or —O—C1-4alkyl;
R7b represents hydrogen or C1-4alkyl;
R4a, R4b and R4c each independently represent hydrogen, halo, —NR8aR8b, or C1-4alkyl;
Q1 represents N or CR6a;
Q2 represents N or CR6b;
Q3 represents N or CR6c;
Q4 represents N or CR6d;
provided that maximum one of Q3 and Q4 represents N;
R6a, R6b, R6c, R6d, R6e and R6f each independently represent hydrogen, halogen, C1-4alkyl, —NR9aR9b, or C1-4alkyl substituted with one, two or three halo atoms.