Patent ID: 11945877
Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C

Claim 4:
5. A method of treating cancer, the method comprising administering an antibody, or antigen binding fragment thereof, to a patient suffering from cancer,
wherein the antibody or antigen binding fragment thereof is capable of binding to HER2, and comprises:
a light chain variable region incorporating the following CDRs:, LC-CDR1:

(SEQ ID NO: 255)

GLSSGSVSTTYYPS

 

LC-CDR2:

(SEQ ID NO: 33)

STNTRSS

 

LC-CDR3:

(SEQ ID NO: 256)

VLYMGNGISV;, and
a heavy chain variable region incorporating the following CDRs:, HC-CDR1:

(SEQ ID NO: 24)

SSSYYWG

 

HC-CDR2:

(SEQ ID NO: 25)

SIYYSGSTYYNPSLKS

 

HC-CDR3:

(SEQ ID NO: 26)

YAPDSSGYLVAFDI.