Patent ID: 11919910
Assignee: ENANTA PHARMACEUTICALS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound represented by Formula (I):, or a pharmaceutically acceptable salt thereof, wherein:
B is an optionally substituted aryl or optionally substituted heteroaryl;
X is an optionally substituted aryl or optionally substituted heteroaryl;
R1, R2, and R3 are each independently selected from:
1) Hydrogen;
2) Optionally substituted —C1-C8 alkyl;
3) Optionally substituted —C2-C8 alkenyl;
4) Optionally substituted —C2-C8 alkynyl;
5) Optionally substituted —C3-C8 cycloalkyl;
6) Optionally substituted 3- to 8-membered heterocycloalkyl;
7) Optionally substituted aryl;
8) Optionally substituted arylalkyl;
9) Optionally substituted heteroaryl; and
10) Optionally substituted heteroarylalkyl;

alternatively, R1 and R2 are taken together with the carbon atom to which they are attached to form an optionally substituted 3- to 8-membered carbocyclic ring or an optionally substituted 3-to 8-membered heterocyclic ring; alternatively, R1 and R3 are taken together with the carbon atom and the nitrogen atom to which they are attached corresponding to form an optionally substituted 4- to 8-membered heterocyclic ring;
R4 is hydrogen, optionally substituted —C1-C4 alkyl, optionally substituted —C2-C4-alkenyl, or optionally substituted —C3-C6 cycloalkyl;
A is selected from:
1) —R11;
2) —OR12;
3) —NR13R14;
4) —C(R21R22)NR13C(O)R11;
5) —C(R21R22)NR13C(O)OR12;
6) —C(R21R22)NR23C(O)NR13R14;
7) —C(R21R22)NR13SO2R11;
8) —C(R21R22)NR13R14;
9) —C(O)R11; and
10) —C(O)NR13R14;

R11 and R12 are each independently selected from:
1) Optionally substituted —C1-C8 alkyl;
2) Optionally substituted —C2-C8 alkenyl;
3) Optionally substituted —C2-C8 alkynyl;
4) Optionally substituted —C3-C8 cycloalkyl;
5) Optionally substituted 3- to 8-membered heterocycloalkyl;
6) Optionally substituted aryl;
7) Optionally substituted arylalkyl;
8) Optionally substituted heteroaryl; and
9) Optionally substituted heteroarylalkyl;

R13, R14, R21, R22, and R23 are each independently selected from:
1) Hydrogen;
2) Optionally substituted —C1-C8 alkyl;
3) Optionally substituted —C2-C8 alkenyl;
4) Optionally substituted —C2-C8 alkynyl;
5) Optionally substituted —C3-C8 cycloalkyl;
6) Optionally substituted 3- to 8-membered heterocycloalkyl;
7) Optionally substituted aryl;
8) Optionally substituted arylalkyl;
9) Optionally substituted heteroaryl; and
10) Optionally substituted heteroarylalkyl;

alternatively, R13 and R14 are taken together with the nitrogen atom to which they are attached to form an optionally substituted 3- to 8-membered heterocyclic ring.