Patent ID: 11952423
Assignee: DAIICHI SANKYO COMPANY, LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 9:
10. The molecule according to claim 7, comprising:
a first polypeptide that comprises, from N terminus to C terminus, an scFv that binds specifically to human HLA/NY-ESO, a heavy chain variable region and constant region CH1 of an antibody or fragment thereof that binds specifically to CD3, and an immunoglobulin Fc region (i);
a second polypeptide that comprises an immunoglobulin hinge region and an immunoglobulin Fc region (ii); and
a third polypeptide that comprises an antibody light chain of the antibody or fragment thereof that binds specifically to CD3, the antibody light chain consisting of a variable region and a constant region;
wherein the first polypeptide is associated with the second polypeptide in the Fc region (i) and in the Fc region (ii), and the first polypeptide is associated with the third polypeptide in the heavy chain variable region and the constant region CH1 of the antibody.