Patent ID: 11958896
Assignee: PROTHENA BIOSCIENCES LIMITED
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 4:
5. The humanized antibody of claim 4 wherein at least one of the following positions is occupied by the amino acid as specified: Kabat position H1 is occupied by Q or E, Kabat position H11 is occupied by V or L, Kabat position H12 is occupied by K or V, Kabat position H19 is occupied by K or R, Kabat position H20 is occupied by V or L, Kabat position H23 is occupied by K or A, Kabat position H46 is occupied E or D, Kabat position H48 is occupied by M or I, Kabat position H66 is occupied by K or R, Kabat position H67 is occupied by A or V, Kabat position H71 is occupied by R or S, Kabat position H76 is occupied by S or N, Kabat position H78 is occupied by A or V, Kabat position H80 is occupied by M or L, Kabat position H93 is occupied by T, S, or A, and Kabat position H94 is occupied by I, P, or R.