Patent ID: 11945868
Assignee: VISTERRA, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An anti-CD138 antibody molecule comprising:
(a) a heavy chain variable region (VH), wherein the VH comprises three heavy chain complementarity determining regions (HCDR1, HCDR2, and HCDR3), wherein the VH comprises:
(i) an HCDR1 comprising the amino acid sequence of SEQ ID NO: 350, 355, or 356, an HCDR2 comprising the amino acid sequence of SEQ ID NO: 351, and an HCDR3 comprising the amino acid sequence of FVY; or
(ii) an HCDR1 comprising the amino acid sequence of SEQ ID NO: 380, an HCDR2 comprising the amino acid sequence of SEQ ID NO: 381 or 382, and an HCDR3 comprising the amino acid sequence of FVY; and

(b) a light chain variable region (VL), wherein the VL comprises three light chain complementarity determining regions (LCDR1, LCDR2, and LCDR3), wherein the VL comprises:
an LCDR1 comprising the amino acid sequence of SEQ ID NO: 352 or an amino acid sequence that differs by 1 conservative amino acid substitution therefrom; an LCDR2 comprising the amino acid sequence of SEQ ID NO: 353; and an LCDR3 comprising the amino acid sequence of SEQ ID NO: 354.