Patent ID: 11945838
Assignee: INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. A site-modified protein/peptide amphiphile selected from the group consisting of:
(i) BSA conjugated at an N-terminal amino acid with 2-pyridine carboxaldehyde functionalized 6-((4-(1-(1-(4-(octadecyloxy)benzyl)-1H-1,2,3-triazol-4-yl)-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)piperazin-1-yl)methyl) picolinaldehyde amphiphilic probe;
(ii) Chymotrypsin conjugated at an N-terminal amino acid with 2-pyridine carboxaldehyde functionalized 6-((4-(1-(1-(4-(octadecyloxy)benzyl)-1H-1,2,3-triazol-4-yl)-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)piperazin-1-yl) methyl) picolinaldehyde amphiphilic probe;
(iii) Lysozyme conjugated at an N-terminal amino acid with 2-pyridine carboxaldehyde functionalized 6-((4-(1-(1-(4-(octadecyloxy)benzyl)-1H-1,2,3-triazol-4-yl)-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)piperazin-1-yl) methyl) picolinaldehyde amphiphilic probe; and
(iv) GFP conjugated at an N-terminal amino acid with 2-pyridine carboxaldehyde functionalized 6-((4-(1-(1-(4-(octadecyloxy)benzyl)-1H-1,2,3-triazol-4-yl)-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)piperazin-1-yl) methyl) picolinaldehyde amphiphilic probe.