Patent ID: 11890412
Assignee: IMPEL PHARMACEUTICALS INC.
Field: Medical technology (Instruments)
Classification: CPC A  B | IPC A  B

Claim 0:
1. A method for delivering a compound to an upper olfactory region of a nasal cavity, the method comprising:
responsive to a nozzle being actuated, the nozzle positioned for intranasal delivery of the compound to a subject, wherein actuating the nozzle pressurizes a proximal end of the nozzle, the nozzle including a drug product inlet at the proximal end of the nozzle and a nozzle body defining a plurality of channels along a longitudinal axis, wherein the channels are disposed parallel to the longitudinal axis and are symmetric about a circle around the longitudinal axis:
transporting a propellant from a propellant chamber and the compound from a compound chamber through the drug product inlet, the drug product inlet configured to receive a mixture of the propellant and the compound;
transporting the mixture from the drug product inlet and through each of the plurality of channels, each of the plurality of channels having a proximal end and a distal end, the proximal end of each of the plurality of channels configured to receive the mixture, the distal end of each of the plurality of channels having an outlet orifice exiting to the nasal cavity; and
releasing the mixture from the outlet orifices of each of the plurality of channels directly into the nasal cavity, wherein once exited, the mixture forms a plume having a width of 5 degrees or less to enable the plume to reach the upper olfactory region of a nasal cavity.