Patent ID: 11946030
Assignee: UNIVERSITY OF CONNECTICUT
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A cell culture system comprising:
a. a culture plate comprising at least one well, wherein each well comprises a bottom and a wall having a height, and
b. one or more branched non-permeable inserts,
i. wherein each well contains no more than one branched non-permeable insert;
ii. wherein each branched non-permeable insert comprises three or more branches; and
iii. wherein each non-permeable insert divides a bottom portion of the well into three or more chambers, wherein each non-permeable insert does not divide the entire top portion of the height of the well, and
A. wherein each non-permeable insert is capable of preventing physical interaction between cell populations in different chambers in a well, and
B. wherein each non-permeable insert is capable of permitting chemical signaling between cell populations in different chambers in a well.