Patent ID: 11872198
Assignee: PURDUE RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method for treating Prader-Willi syndrome, the method comprising parenterally administering to an obese subject with Prader-Willi syndrome (PWS) a composition comprising an effective amount of avasimibe that non-selectively inhibits in vivo both acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) and acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2), wherein the degree that the avasimibe inhibits ACAT1 is less than the degree that the avasimibe inhibits ACAT2 and wherein the composition suppresses food intake of the obese PWS subject.