Patent ID: 11883679
Assignee: NORTH CAROLINA STATE UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 0:
1. A system comprising:
a plurality of magnetic microbubbles (MMBs) having a gas core and a layer of superparamagnetic nanoparticles around the gas core,
an ultrasound transducer effective to induce cavitation of the MMBs, wherein the ultrasound transducer is configured to generate an acoustic frequency of about 100 kHz to about 5 MHz, with an ultrasound duty cycle of about 0.5% to about 25%, and an input voltage of about 10Vpp to 250 Vpp, and
a rotational magnetic field generator effective to accumulate MMBs in a target region and increase cavitation of the MMBs induced by the ultrasound transducer.