Patent ID: 11964941
Assignee: CITY OF HOPE
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC A  C

Claim 10:
11. A method of modulating activity of a FLT3-kinase, said method comprising contacting a FLT3-kinase with a compound having formula:, wherein,
L is a substituted or unsubstituted alkylene;
R1 is —NR2R3;
R2 and R3 are independently substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl, wherein R2 and R3 are optionally joined together to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl; and
R5 and R6 are independently hydrogen or halogen;
including pharmaceutically acceptable salts thereof,
thereby modulating said activity of said FLT3-kinase.