Patent ID: 11896845
Assignee: THE CLEVELAND CLINIC FOUNDATION
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 8:
9. A method comprising:
receiving, by a system comprising a processor, a radiation procedure comprising a total dose of radiation to be administered in a time period, wherein the time period is at least three days;
determining, by the system, a target volume for the radiation procedure based on at least one image;
determining, by the system, an organ outside of the target volume at risk of acute toxicity from the radiation procedure based on the at least one image;
constructing, by the system, a sequence plan that ensures the total dose of radiation is administered in the time period and reduces the risk of acute toxicity of the organ, wherein the sequence plan comprises at least one subset of the time period when a high fractional dose of radiation is applied and remaining subsets of the time period when a low fractional dose of radiation is applied, wherein a sum of the high fractional dose of radiation delivered on the at least one subset of the time period and the low fractional doses of radiation delivered on the remaining subsets of the time period equals the total dose of radiation administered in the time period;
sending, by the system, the sequence plan to a computing device associated with a radiation delivery device to perform the radiation procedure;
delivering, by the system, the total dose of radiation to a patient associated with the target volume according to the sequence plan; and
transmitting, by the system, information associated with the delivery of the sequence plan back to the computing device, wherein the computing device determines a new sequence plan for a next time period based on the transmitted information.