Patent ID: 11897907
Assignee: LIER CHEMICAL CO., LTD.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  Y | IPC C

Claim 0:
1. A method for preparing a glufosinate of formula (I) or an analogue thereof,, , which method comprises:
a) feeding a compound of formula (II) and a compound of formula (V) into a first reactor set, wherein after reaction, a product stream of the first reactor set is obtained,, b) feeding the product stream of the first reactor set into a second reactor set, and reacting the product stream at a temperature in the range of from 50° C. to 200° C. to obtain a product stream of the second reactor set; and
c) subjecting the product stream of the second reactor set to an acidic hydrolysis or a basic hydrolysis to obtain the glufosinate of formula (I) or an analogue thereof;
wherein X represents —OR2 or —NR2R′,
R1, R2 and R7 are each independently selected from a substituted or unsubstituted hydrocarbyl group;
R′ is hydrogen or has the same definition as R2;
Hal1 and Hal2 are each independently halogen; and
PG is hydrogen or an amino protecting group; and
wherein the feeding in the step a) and/or step b) is/are a continuous feeding.