Patent ID: 11912760
Assignee: PHAROSGEN CO., LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 23:
24. A doppel-targeting molecule according to claim 23, wherein the doppel-targeting molecule is selected from:
a chimeric antibody comprising a light chain that comprises the amino acid sequence of SEQ ID NO: 155 and a heavy chain that comprises the amino acid sequence of SEQ ID NO: 157, and doppel-binding fragments thereof;
a chimeric antibody comprising a light chain that comprises the amino acid sequence of SEQ ID NO: 159 and a heavy chain that comprises the amino acid sequence of SEQ ID NO: 161,and doppel-binding fragments thereof;
a humanized antibody comprising a light chain that comprises the amino acid sequence of SEQ ID NO: 163 and a heavy chain that comprises the amino acid sequence of SEQ ID NO: 165, and doppel-binding fragments thereof;
a humanized antibody comprising a light chain that comprises the amino acid sequence of SEQ ID NO: 167 and a heavy chain that comprises the amino acid sequence of SEQ ID NO: 169, and doppel-binding fragments thereof.