Patent ID: 11858922
Assignee: THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 32:
33. A prodrug of a compound, or a pharmaceutically acceptable salt or solvate thereof, wherein the compound is a compound of formula (II) or (III), or a pharmaceutically acceptable salt or solvate thereof:, wherein:
each R1 is independently selected from a hydrogen atom and pyrazole, imidazole, triazole, tetrazole, pyrrole, morpholine, piperazine, 4-methyl piperazine, and fused bicyclics or tricyclics comprising a benzene ring fused with at least one 5-membered heterocycle, each of which groups may be optionally substituted at a ring atom with a group selected from halo, isopropyl, morpholinyl, piperidinyl, and piperazinyl, each of which groups may themselves be optionally substituted with C1-C6 alkyl;
A is selected from pyrazole, imidazole, triazole, tetrazole, pyrrole, morpholine, piperazine, 4-methyl piperazine, and fused bicyclics or tricyclics comprising a benzene ring fused with at least one 5-membered heterocycle, each of which groups may be optionally substituted at a ring atom with a group selected from halo, isopropyl, morpholinyl, piperidinyl, and piperazinyl, each of which groups may themselves be optionally substituted with C1-C6 alkyl; and
W2 and R2 form an indacene group or a substituted or hydrogenated variant thereof.