Patent ID: 11945845
Assignee: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 13:
14. A method of delivering an antigen to a subject in need thereof, the method comprising administering the antigen to the subject a wherein the antigen is delivered in a genetically altered Toxoplasma gondii, wherein the Toxoplasma gondii comprises a mutation in a bradyzoite formation deficient 1 (BFD 1) gene (SEQ ID NO:1), wherein the mutation is a deletion of all or a portion of the coding sequence of the BFD 1 gene, and wherein the mutant BFD 1 gene is defective in initiating differentiation of the Toxoplasma gondii into a bradyzoite.