Patent ID: 11857294
Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 0:
1. A medical device for measuring tissue properties in a subject, comprising:
a light-guiding cone comprising an opaque, anti-reflective, sloped surface and having optical properties that direct light along an optical excitation path into a homogeneous field on a tissue of interest in the subject;
a plurality of excitation light sources disposed at an open end of the light-guiding cone, each of said plurality emitting light at a wavelength from visible to near infrared;
an image sensor configured to measure intensities of light with different wavelengths reflected from the tissue of interest;
a radially extruded lip at the end of the light-guiding cone disposed to cover an area of the tissue of interest under interrogation and to prevent ambient light from impinging on the area;
at least one pressure sensor configured to sense conformal attachment of the medical device to the surface of the tissue of interest;
and
a processor and a memory in electronic communication with the device and tangibly storing an algorithm for processing the reflected wavelengths as a measurement of tissue properties, said algorithm comprising processor-executable instructions that perform all of the following to:
predict an Ankle Brachial Index from measurements of tissue oxygenation, tissue temperature, or perfusion index or a combination thereof at at least one wavelength;
correlate tissue oxygenation measurements from an upper limb and a lower limb of the subject to the Ankle Brachial Index;
measure a photoplethysmography signal; and
predict peripheral artery disease in the subject.