Patent ID: 11923063
Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
Field: Medical technology (Instruments)
Classification: CPC G | IPC G

Claim 6:
7. A method of controlling the delivery of insulin to a subject and comprising:
recording, using one or more body worn or implantable electrodes, neural information from the subject's nervous system indicative of prospective or actual food and/or drink intake;
determining food and/or drink characteristics based on the recorded neural information;
measuring the subject's blood glucose level using a body worn or implantable blood plasma glucose sensor;
determining an amount of insulin to be delivered based on the measured blood glucose level and the determined food and/or drink characteristics; and
providing a control signal indicative of the determined amount of insulin to an insulin pump to thereby deliver a required amount of insulin from the insulin pump to the subject;
recording, using one or more body worn or implantable electrodes, a neural signal from nerves innervating the liver and/or brown adipose tissue and/or nuclei of the hypothalamus indicative of the subject's insulin sensitivity;
determining a characteristic of a neural stimulation signal to be applied to the subject using said neural signal indicative of the subject's insulin sensitivity; and
applying that stimulation signal to the subject's efferent sympathetic nerves to the liver and/or brown adipose tissue and/or hypothalamic areas via one or more body worn or implantable electrodes in order to increase or decrease the subject's insulin sensitivity during delivery of the determined amount of insulin.