Patent ID: 11919868
Assignee: RECURSION PHARMACEUTICALS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A compound of Formula (I):, or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof;
wherein
X1, X2, and X3 are each independently CR2, N, NR5, O, or S;
X4 and X5 are each independently C(H) or N;
m is an integer of 0, 1, or 2;
Z is a 6- to 10-membered aryl or, 5- to 10-membered heteroaryl containing 1 to 3 heteroatoms independently selected from N, O, and S;
R1 and R2 are each independently hydrogen, halo, cyano, hydroxyl, amino, C1-6 alkyl, alkylamino, haloalkyl, hydroxyalkyl, aminoalkyl, alkoxyalkyl, haloalkoxyalkyl, alkoxy, or haloalkoxy;
R3 and R4 are each independently hydrogen, C1-6 alkyl, alkylamino, haloalkyl, alkoxy, haloalkoxy, 6- to 10-membered aryl, 5- to 10-membered heteroaryl containing 1 to 3 heteroatoms independently selected from N, O, and S, 3- to 10-membered carbocyclyl, or 4- to 10-membered heterocyclyl containing 1 to 3 heteroatoms independently selected from N, O, and S, wherein the aryl, heteroaryl, carbocyclyl, and heterocyclyl are independently substituted with 0 to 5 R5;
R5 is hydrogen, halo, cyano, hydroxyl, amino, C1-6 alkyl, alkylamino, haloalkyl, hydroxyalkyl, hydroxycycloalkyl, aminoalkyl, alkoxyalkyl, haloalkoxyalkyl, alkoxy, haloalkoxy or —C(O)OR6; and
R6 is hydrogen or C1-6 alkyl.