Patent ID: 11865195
Assignee: LANTHEUS MEDICAL IMAGING, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  G | IPC A

Claim 3:
4. A method for identifying a subject having a history of atrial fibrillation that is likely to respond to treatment with an implantable pacer, pharmacological rate control therapy, pharmacological rhythm control therapy, or ablation therapy, comprising:
administering, to a subject previously diagnosed with atrial fibrillation, imaging agent 99mTc-RP805:, wherein TPPTS is 3,3′,3″-Phosphanetriyltris(benzenesulfonic acid) trisodium salt; and
acquiring an image of the atria or the aortic valve region of the subject,
wherein the image indicates an aggregate level of MMP comprising MMP-2, MMP-9 and MMP-14 in the atria or the aortic valve region of the subject, and
wherein an aggregate level of MMP in the atria or the aortic valve region of the subject above control identifies a subject that is likely to respond to treatment with an implantable pacer, pharmacological rate control therapy, pharmacological rhythm control therapy, or ablation therapy.