Patent ID: 11859001
Assignee: SYNTHEKINE, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. An IL12Rb1 binding molecule that specifically binds to the extracellular domain of IL12Rb1, wherein the IL12Rb1 binding molecule comprises a single domain antibody (sdAb), and wherein the sdAb comprises:
(1) a complementary determining region 1 (CDR1) comprising the sequence of SEQ ID NO:24, a CDR2 comprising the sequence of SEQ ID NO:25, and a CDR3 comprising the sequence of SEQ ID NO:26;
(2) a CDR1 comprising the sequence of SEQ ID NO:87, a CDR2 comprising the sequence of SEQ ID NO:88, and a CDR3 comprising the sequence of SEQ ID NO:89; or
(3) a CDR1 comprising the sequence of SEQ ID NO:75, a CDR2 comprising the sequence of SEQ ID NO:76, and a CDR3 comprising the sequence of SEQ ID NO:77.