Patent ID: 11946087
Assignee: AMYRIS BIO PRODUCTS PORTUGAL, UNIPESSOAL, LDA
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A method for co-production of two or more isoprenoids, the method comprising:
(a) culturing, in a culture medium, a host cell genetically modified with one or more heterologous nucleic acids encoding one or more enzymes in a first biosynthetic pathway to produce a first isoprenoid and with one or more heterologous nucleic acids encoding one or more enzymes in a second biosynthetic pathway to produce a second isoprenoid, which has a molecular weight that is different from the first isoprenoid wherein the first isoprenoid is produced and secreted into the culture medium, and wherein the second isoprenoid is produced and remains associated with the host cell, and wherein the host cell co-produces about 2.5 g/L to about 200 g/L of the first isoprenoid compound and about 1 mg/L to about 4000 mg/L of the second isoprenoid compound;
(b) recovering the first isoprenoid from the culture medium; and
(c) recovering the second isoprenoid from the host cell.