Patent ID: 11861475
Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Field: Computer technology (Electrical engineering)
Classification: CPC G | IPC G

Claim 0:
1. A method for constructing and implementing a hybrid machine learning and mechanistic model to predict biological feature data, the steps of the method comprising:
constructing a hybrid machine learning and mechanistic model by:
(i) accessing training data with a computer system, the training data including labeled data and unlabeled data;
(ii) training a machine learning model based on the training data, generating output that includes a trained machine learning model;
(iii) augmenting the machine learning model using a mechanistic model that mathematically describes at least one of a biological process or a physiological process associated with a biological feature, generating a hybrid model comprising a hybrid machine learning and mechanistic model; and

generating predicted biological feature data by inputting multiparametric magnetic resonance images to the hybrid model.