Patent ID: 11969396
Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A nanoparticulate composition comprising a p21 activated kinase (PAK) inhibitor and a lipid-based delivery vehicle,
wherein the p21 activated kinase (PAK) inhibitor is Inhibitor targeting P21-activated kinase-1 (PAK1) activation-3 (IPA-3), a prodrug, or a pharmaceutically acceptable salt thereof, and
wherein the lipid-based delivery vehicle is a liposome which consists essentially of: (1) 1, 2-distearoyl-sn-glycero-3-phosphatidylcholine (DSPC) and/or 1, 2-distearoyl -sn-glycero-3-phosphatidylethanolamine (DSPE); (2) at least one pegylated lipid; and (3) cholesterol.