Patent ID: 11878311
Assignee: PNEUMATIC SCALE CORPORATION
Field: Chemical engineering (Chemistry)
Classification: CPC B  C | IPC B

Claim 17:
18. The apparatus according to claim 1
wherein the single use structure further includes:
a vertically extending concentrate discharge tube,
wherein during rotation of the bowl, the upper disc shape portion and the outer wall rotate relative to the concentrate discharge tube,

a concentrate centripetal pump, wherein the concentrate centripetal pump is
axially aligned with the core,
disposed coaxially about the feed tube,
vertically positioned above the centrate centripetal pump,
in fluid communication with the concentrate discharge tube, and
positioned in a concentrate pump chamber,
wherein the concentrate pump chamber is in fluid communication with the separation chamber,

wherein during rotation of the bowl the upper disc shape portion and the outer wall rotate relative to the concentrate centripetal pump,
at least one annular air tight seal,
wherein the at least one seal extends in operatively sealing relation between the upper disc shaped portion and at least one annular outer wall that extends radially outwardly of at least one of the feed tube, the centrate discharge tube and the concentrate
discharge tube,
and further comprising:
a source of pressurized air, wherein the source of pressurized air is outside the single use structure,
wherein the centrate centripetal pump includes a substantially annular centrate pump opening, wherein centrate passes from the centrate pump chamber through the substantially annular centrate pump opening,
wherein the concentrate centripetal pump includes a substantially annular concentrate pump opening, wherein concentrate passes from the concentrate pump chamber through the substantially annular concentrate pump opening,
wherein the at least one seal is operative to maintain an air pocket within the interior area, wherein the source of pressurized air is in fluid connection with the air pocket,
wherein the air in the air pocket isolates the at least one seal from the cell culture batch being processed, and wherein the air pocket is positioned radially inwardly of each of the substantially annular centrate pump opening and the substantially annular concentrate pump opening.