Patent ID: 11865173
Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 6:
7. A nucleic acid sequence encoding a chimeric hemagglutinin (HA) polypeptide, wherein the chimeric HA polypeptide comprises:
a. the amino acid sequence set forth in SEQ ID NO: 21, or the amino acid set forth in SEQ ID NO: 21 without the signal peptide;
b. the amino acid sequence set forth in SEQ ID NO: 23 or SEQ ID NO: 25, or the amino acid sequence set forth in SEQ ID NO: 23 or SEQ ID NO: 25 without the signal peptide;
c. the amino acid sequence of the influenza virus HA ectodomain set forth in SEQ ID NO: 21;
d. the amino acid sequence of the influenza virus HA ectodomain set forth in SEQ ID NO: 23 or SEQ ID NO: 25;
e. the amino acid sequence set forth in SEQ ID NO: 44, SEQ ID NO: 46, SEQ ID NO: 48, or SEQ ID NO: 50, or the amino acid sequence set forth in SEQ ID NO: 44, SEQ ID NO: 46, SEQ ID NO: 48, or SEQ ID NO: 50 without the signal peptide; or
f. the amino acid sequence of the influenza virus HA ectodomain set forth in SEQ ID NO: 44, SEQ ID NO: 46, SEQ ID NO: 48, or SEQ ID NO: 50.