Patent ID: 11965887
Assignee: THEORIA SCIENCE INC.
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C  G

Claim 2:
3. A method of monitoring a subject for pancreatic cancer, comprising:
measuring at least twice consecutively a concentration of GPRC5C (G protein-coupled receptor family C group 5 member C) present in an exosome in blood collected from the subject having pancreatic cancer before performing treatment on the subject by using an immunoassay method; and
measuring a concentration of GPRC5C present in an exosome in blood collected from the subject after performing the treatment on the subject; and
monitoring a therapeutic effect after performing the treatment on the subject and a decrease in cancer sites of the pancreatic cancer of the subject based on the measured concentration of GPRC5C present in the exosome in the blood collected from the subject having pancreatic cancer before performing the treatment and after performing the treatment on the subject,
wherein the immunoassay method is carried out by using an antibody binding to GPRC5C or a fragment of the antibody and an antibody binding to an antigen specifically expressed in an exosome-specific antigen or a fragment of the antibody, and
wherein the exosome-specific antigen is CD63, CD9, CD81, CD37, CD53, CD82, CD13, CD11, CD86, ICAM-1 (intercellular adhesion molecule-1), Rab5, Annexin V, or LAMP1 (lysosome-associated membrane protein 1).