Patent ID: 11958831
Assignee: ARTIVILA (SHENZHEN) INNOVATION CENTER, LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound represented by Formula (I) or a pharmaceutically acceptable salt thereof, wherein the compound represented by Formula (I) has the following structure:, wherein
the Het ring is a five- or six-membered heteroaromatic ring;
R1 is selected from H or D;
R2 and R3 are each selected from H, D, alkyl, halogen, or ORa;
R4 is selected from CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc;
R5 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, SO2NRbRc, alkyl, alkenyl, alkynyl, cycloalkyl, or heterocycloalkyl; wherein the alkyl, alkenyl, alkynyl, cycloalkyl, or heterocycloalkyl is unsubstituted or substituted with 1 to 3 R5a;
R5a is selected from H, D, halogen, cyano, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc; wherein the alkyl, cycloalkyl, or heterocycloalkyl is unsubstituted or substituted with 1 to 3 R5b;
R5b is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc;
Ra, Rb, Rc, and Rd are each selected from H, D, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl is unsubstituted or substituted with 1 to 4 R6;
R6 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, NRbCORd, NRbCONRbRc, CONRbRc, CO2Rd, NRbSO2Rd, NRbSO2NRbRc, SORd, SO2Rd, SO2NRbRc, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl;
wherein Rb and Rc in a group containing both Rb and Rc are attached to a N atom in the group by a single bond or form a heterocycloalkyl together with the N atom to which they are attached, and the heterocycloalkyl is unsubstituted or substituted with 1 to 3 R7;
R7 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, NRbCORd, NRbCONRbRc, CONRbRc, CO2Rd, NRbSO2Rd, NRbSO2NRbRc, SORd, SO2Rd, SO2NRbRc, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and
m, n, p, q, and y are each independently 1, 2, or 3.