Patent ID: 11911499
Assignee: RESURGE THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of treatment for benign prostatic hyperplasia (BPH), comprising the steps of:
using a needle syringe containing a composition; and
dispensing a plurality of doses of the composition into a prostate at a respective plurality of locations within the prostate using the needle syringe;
wherein the composition comprises:
a cytotoxic drug, wherein the cytotoxic drug is paclitaxel;
a glycolide-based bioabsorbable copolymer selected from the group consisting of poly(D,L-lactide-co-glycolide) (50:50), poly(D,L-lactide-co-glycolide) (65:35), poly(D,L-lactide-co-glycolide) (75:25), and poly(D,L-lactide-co-glycolide) (85:15); and
a water-soluble solvent capable of dissolving the cytotoxic drug and glycolide-based bioabsorbable copolymer;

wherein the water-soluble solvent capable of dissolving the cytotoxic drug and glycolide-based bioabsorbable copolymer is selected from the group consisting of N-methylpyrrolidone (NMP) and dimethyl sulfoxide (DMSO); and
wherein the dispensing a plurality of doses comprises consecutively dispensing at least a first dose of the composition into a first location, and a second dose of the composition into a second location within the prostate using the needle syringe.