Patent ID: 11866450
Assignee: VERTEX PHARMACEUTICALS INCORPORATED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 20:
21. The method of claim 19, wherein each R4 is independently chosen from an oxo group or —O-(Y)k-R7 groups, wherein:
k is 0, 1, 2, 3, 4, or 5;
each Y is independently chosen from C(R5)(R6) groups, —O—, and —NRa— groups, wherein a heteroatom in -(Y)k-R7 is not bonded to another heteroatom in -(Y)k-R7, and wherein:
each R5 and R6 is independently chosen from hydrogen, deuterium, halogens, a hydroxyl group, C1-C4 alkyl groups, and C3-5 cycloalkyl groups, or R5 and R6 on the same carbon together form a C3-5 cycloalkyl group or oxo;
each of R5 and R6 is optionally independently substituted with one or more groups chosen from C1-C2 alkyl groups, C1-C2 haloalkyl groups, halogens, a hydroxyl group, C1-C2 alkoxyl groups, and C1-C2 haloalkoxyl groups; and

each Ra is independently chosen from hydrogen and C1-C2 alkyl groups; and
R7 is chosen from hydrogen, halogens, a cyano group, and C3-C10 cycloalkyl groups optionally substituted with one or more groups chosen from C1-C2 alkyl groups, C1-C2 haloalkyl groups, and halogens.