Patent ID: 11896736
Assignee: GLOBUS MEDICAL INC.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 13:
14. A method of making an implantable biomaterial for aiding bone regeneration, the method comprising:
obtaining whole bone;
separating the whole bone into condyles and cortical shafts;
grinding the condyles into cortico-cancellous chips having a size less than 1.5 mm;
machining the cortical shafts into cortical fibers having a size of 15-30 mm;
demineralizing the cortical fibers;
combining the cortico-cancellous chips and demineralized cortical fibers with a carrier, wherein the carrier is a reverse phase hydrogel;
wherein prior to demineralizing, the cortical shafts are cleaned with a 0.05-0.15% v/v sodium deoxycholate solution, a 2-6% hydrogen peroxide solution, and an isopropyl alcohol solution.