Patent ID: 11919855
Assignee: NORTHWESTERN UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A compound having a formula I:, or a pharmaceutically acceptable salt thereof, wherein m is 0-2, n is 0-1, and p is 0-1, with the proviso that (m+n+p) is 2 or 3;
wherein A is —C(R1)(R2)—;
wherein R1, R2, and R3 are independently selected from hydrogen and alkyl;
wherein R′ is selected from hydrogen, alkyl, hydroxyalkyl, cycloalkyl, heterocycloalkyl, alkyl(heterocycloalkyl), aryl, heteroaryl, alkyl(aryl), and alkyl(heteroaryl), and R′ is optionally substituted at one or more positions with a substituent selected from alkyl, alkoxy, halogen, haloalkyl, amino, cyano, nitro, aryl, hydroxyl, carboxyl, carboxy(alkyl) ester, acyl, and oxo; and
wherein
X is selected from —N(R3)—C(O)—, —N(R3)—CH2—, —N(R3)—C(O)—CH2—, —N(R3)—, —N(R3)—S(O)(O)—, and —C(O)—N(R3)— and R is selected from hydrogen, alkyl, hydroxyalkyl, cycloalkyl, heterocycloalkyl, alkyl(heterocycloalkyl), aryl, heteroaryl, alkyl(aryl), and alkyl(heteroaryl), and R is optionally substituted at one or more positions with a substituent selected from alkyl, alkoxy, halogen, haloalkyl, amino, cyano, nitro, aryl, hydroxyl, carboxyl, carboxy(alkyl) ester, acyl, and oxo; or
X is —CH2—N(R3)—C(O)— and R is selected from hydrogen, alkyl, hydroxyalkyl, cycloalkyl, heterocycloalkyl, alkyl(heterocycloalkyl), aryl, heteroaryl, alkyl(aryl), and alkyl(heteroaryl), and R is optionally substituted at one or more positions with a substituent selected from alkyl, alkoxy, halogen, haloalkyl, unsubstituted amino, cyano, nitro, unsubstituted aryl, hydroxyl, carboxyl, carboxy(alkyl) ester, acyl, and oxo.