Patent ID: 11883463
Assignee: SALUS UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of restoring photosensitivity to retinal neurons of a subject suffering from vision loss or blindness, which method comprises: (a) delivering to a retina of said subject in which photoreceptors are degenerating or have already died a nucleic acid vector comprising a nucleic acid encoding a polypeptide of SEQ ID NO: 3 or a polypeptide having 98% or 99% sequence identity thereto, operably linked to a promoter sequence; and (b) expressing said polypeptide in said retinal neurons, wherein the expression of the polypeptide renders said retinal neurons photosensitive, thereby restoring photosensitivity to said retinal neurons.