Patent ID: 11939295
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 10:
11. A method of making the 6-(3-hydroxyphenyl)-2-methoxy-4-(3-methylphenyl)nicotinonitrile compound of claim 1, the method comprising:
adding a mixture of 3′-hydroxyacetophenone, m-tolualdehyde and malonitrile to a solution of a sodium ethoxide in an absolute ethanol to obtain a reaction mixture;
irradiating the reaction mixture followed by cooling to room temperature to obtain a solid precipitate;
purifying the solid precipitate by filtering and recrystallization using ethanol; and
obtaining the 6-(3-hydroxyphenyl)-2-methoxy-4-(3-methylphenyl)nicotinonitrile compound.