Patent ID: 11872241
Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 1:
2. A method for reducing or preventing formation of a thrombus in a patient with cancer comprising administering to the patient an effective amount of isoquercetin, vitamin B3, and vitamin C for a period of at least about 2 months; wherein the patient has been diagnosed with a cancer and is at an increased risk of bleeding; and exhibits an elevated level of soluble P-selectin prior to administration of isoquercetin, when compared to a reference or baseline level of soluble P-selectin; wherein the dose of isoquercetin is 500 mg per day wherein the patient does not exhibit primary venous thromboembolism (VTE) during treatment or after administration of the effective amount of isoquercetin, vitamin B3, and vitamin C for a period of at least about 2 months; and wherein soluble P-selectin is decreased at least about 30% when compared to a reference or baseline level of soluble P-selectin, following administration of the isoquercetin.