Patent ID: 11963519
Assignee: NORTHWEST INSTITUTE OF PLATEAU BIOLOGY, CAS
Field: Biotechnology (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A method for constructing a long-acting depression animal model, comprising a step of administering Bacille Calmette-Guerin (BCG) and pertussis toxin (PTX) for combined induction, comprising:
intraperitoneally injecting 50 μL to 400 μL of a working solution of BCG into a mouse on day 0, and intraperitoneally injecting 50 μL to 400 μL of a working solution of PTX into the mouse on day 0 to day 1 and day 2 to day 3;
wherein the working solution of BCG has an M. bovis CFU concentration of 1×106 to 6×107 CFU/mL; and
the working solution of PTX has a concentration of 0.5 μg/mL to 4 μg/mL.