Patent ID: 11938169
Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 20:
21. A method of treating a pulmonary non-tuberculous mycobacterium (NTM) infection in a subject having a pulmonary NTM infection refractory to antibiotic treatment, the method comprising:
administering to the subject once or twice daily, via pulmonary administration, between 200 μg and 400 μg of a granulocyte-macrophage colony stimulating factor (GM-CSF) comprising a polypeptide having at least 90% sequence identity with SEQ ID NO:1, wherein the GM-CSF is administered to the subject every week or every alternate week for at least 6 months until a sputum sample originating from the subject shows an absence of NTM, thereby treating the subject; and
wherein the NTM infection is Mycobacterium abscessus infection, a Mycobacterium intracellulare infection, or a Mycobacterium abscessus infection and a Mycobacterium intracellulare infection.