Patent ID: 11887696
Assignee: DEEP GENOMICS INCORPORATED
Field: Computer technology (Electrical engineering)
Classification: CPC G | IPC G

Claim 0:
1. A system comprising a deep neural network for computing a set of variant-induced changes in one or more condition-specific cell variables for one or more genetic variants, comprising:
a. an input layer configured to receive as input (i) a set of reference features extracted from a deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) reference sequence, and (ii) a set of variant features extracted from a DNA or RNA variant sequence, wherein the DNA or RNA variant sequence comprises the one or more genetic variants of the DNA or RNA reference sequence; and
b. at least two connected layers configured to:
i. process the set of variant features to quantify one or more condition-specific variant cell variables;
ii. process the set of reference features to quantify one or more condition-specific reference cell variables; and
iii. generate the set of variant-induced changes in the one or more condition-specific cell variables at least in part by processing the one or more condition-specific reference cell variables with the one or more condition-specific variant cell variables.