Patent ID: 11866409
Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORPORATION LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 8:
9. A method for treating, inhibiting, reducing, eliminating, protecting or delaying the onset of a proliferative disorder in a subject in need thereof, said method comprises administering to said subject a therapeutically effective amount of at least one ARTS mimetic compound any vehicle, matrix, nano- or micro-particle or any composition comprising the same, said ARTS mimetic compound having the general formula (I) or a pharmaceutically acceptable salt or hydrate thereof including any stereoisomer thereof, wherein:
R1 is independently selected from H, C1-C3 alkyl;
R2 is independently selected from —C(═O)—X—R3, —S(═O)—X—R3′; 
X is a heteroatom independently selected from O;
R3 and R3′, independently of each other may be selected independently from H, C1-C3 alkyl;
R5 is -L1-R7-L2-R8;
L1 and L2, independently of each other, are selected independently from —(CH2)n—; —NH—C(═O)—(CH2)n—, —C(═O)—NH—(CH2)n—; —S—S—(CH2)n—; —O—(CH2)n—; —NH—(CH2)n—; C(═O)—(CH2)n—; —S—(CH2)n—; —NH—S(═O)n—(CH2)n—;
n is independently 1 to 3;
R7 is a carbocyclic ring or a heterocyclic ring;
R8 is a mono cyclic ring system having 5 to 12 atoms, optionally substituted with at least one of OH, CF3, halogen, —COOH, —NH2, CN, C1-C3alkyl; and
R6 is independently selected from H, halogen, CN, NO2, C1-C3 alkoxy, straight or branched C1-C3 alkyl.