Patent ID: 11932841
Assignee: UBE CORPORATION
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 0:
1. A cell culture apparatus comprising:
(a) a cell culture module;
(b) a cell culture vessel, which is used for suspension culture; and
(c) a cell culture device;
wherein the cell culture module comprises:
(I) a porous polymer film that is a porous polyimide film; and
(II) a casing having two or more medium flow inlets, the casing containing the porous polymer film,

wherein the porous polymer film is a three-layer structure porous polymer film having a surface layer A and a surface layer B, the surface layers having a plurality of pores, and a macrovoid layer sandwiched between the surface layers A and B;
wherein an average pore diameter of the pores present in the surface layer A is smaller than an average pore diameter of the pores present in the surface layer B;
wherein the macrovoid layer has partition walls bonded to the surface layers A and B, and a plurality of macrovoids surrounded by such partition walls and the surface layers A and B;
wherein the pores in the surface layers A and B communicate with the macrovoid; and
wherein the porous polymer film is contained within the casing with:
two or more independent porous polymer films being stacked;
wherein the porous polymer films are fixed in the casing, thereby preventing the porous polymer film from waving by fluid,
wherein the cell culture module is used in a floating and a shaking or a stirring state in the cell culture vessel placed in the cell culture device,
wherein the cell culture module is not fixed within the cell culture vessel, and
wherein the casing comprises polyethylene, polypropylene, nylon, polyester, polystyrene, polycarbonate, polymethyl methacrylate, polyethylene terephthalate, stainless steel, or titanium.