Patent ID: 11957796
Assignee: THE UNIVERSITY OF TOKYO
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  B | IPC A

Claim 0:
1. An isolated nanosheet comprising a plurality of pseudo-polyrotaxanes and/or polyrotaxanes each having one or more first cyclic molecules and one or more linear molecules included in a cavity of at least one of the one or more first cyclic molecules in a skewered manner,
wherein the one or more linear molecules include, as part thereof, first linear molecules each having an ionizable group that ionizes in water or an aqueous solution,
each of the first linear molecules is (i) a linear molecule including a linear polymer formed of only one type of repeating unit or (ii) a block copolymer including at least three blocks,
when each of the first linear molecules is (i) the linear molecule including the linear polymer formed of only one type of repeating unit, the linear polymer includes polyethylene glycol (PEG) and at least one of the first cyclic molecules is a cyclodextrin,
when each of the first linear molecules is (i) the linear molecule including a linear polymer formed of only one type of repeating unit, the inclusion ratio of the pseudo-polyrotaxanes and/or the polyrotaxanes is at least 95% when the specified inclusion ratio is set to 100%,
when each of the first linear molecules is (ii) the block copolymer including at least three blocks, the block polymer includes PEO-PPO-PEO and at least one of the first cyclic molecules is a cyclodextrin, and
when each of the first linear molecules is (ii) the block copolymer including at least three blocks, the inclusion ratio of the pseudo-polyrotaxanes and/or the polyrotaxanes is at least 10% when the specified inclusion ratio is set to 100%.