Patent ID: 11939577
Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 8:
9. An antisense RNA targeting an mRNA encoding PMP22 protein, wherein said antisense RNA is a nucleic acid complementary to:
(i) a portion consisting of or comprised within:
nucleotides 970 to 988 of sequence SEQ ID NO: 9,
nucleotides 431 to 449 of sequence SEQ ID NO: 11,
nucleotides 429 to 447 sequence SEQ ID NO: 9,

(ii) a portion consisting:
nucleotides 1721 to 1739 of sequence SEQ ID NO: 11,
nucleotides 1726 to 1744 sequence SEQ ID NO: 9,
nucleotides 1805 to 1823 of sequence SEQ ID NO: 11,
nucleotides 1809 to 1827 sequence SEQ ID NO: 9,

wherein said antisense RNA is a siRNA, and
said antisense RNA has a length of from 12 to 50 nucleotides.