Patent ID: 11890395
Assignee: AVERY THERAPEUTICS, INC.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A tissue composition for implantation onto cardiac tissue, said tissue composition comprising:
a. a scaffold having a flat orientation comprising a first fiber type and a second fiber type in a knitted or woven configuration with pores therein, the first fiber type comprising glycolide, lactide, and trimethylene carbonate and the second fiber type comprising lactide and trimethylene carbonate, the first fiber type having a degradation profile different from that of the second fiber type;
b. extracellular matrix (ECM)-generating cells and ECM incorporated on the scaffold or on and within the scaffold;
c. inducible pluripotent stem cell-derived cardiomyocytes, pluripotent stem cell-derived cardiomyocytes, cardiac progenitor cells, or cardiomyocytes therein and forming an intact syncytium.