Patent ID: 11857679
Assignee: UNIVERSITY OF SOUTH FLORIDA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  Y | IPC A

Claim 0:
1. A method of producing an aqueous emulsion of a homopolymer consisting of a polymerized acrylolated drug monomer, the method comprising:
a) dissolving the acrylolated drug monomer in an organic solvent to form a solution;
b) dissolving a detergent in water at a temperature of between 25° C. and 35° C. to form a solution;
c) mixing the solution of detergent in water with the solution of the acrylolated drug monomer in the organic solvent;
d) under constant stirring, increasing the temperature of the mixture produced in c) to between 80° C. and 100° C.;
e) contacting the mixture produced in d) with potassium persulfate and optionally, additional water; and
f) stirring the mixture produced in e) to produce the aqueous emulsion of the homopolymer consisting of the polymerized acrylolated drug monomer,
wherein the acrylolated drug monomer is an antibiotic selected from a β-lactam or a fluoroquinolone.