Patent ID: 11884971
Assignee: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 18:
19. The method of claim 18, further comprising:
(e) repeating steps (a) through (d), wherein the nucleotide cognate of the third base type comprises a reversible terminator, and wherein nucleotide cognates of the first, second and fourth base types are extendable, and wherein the base multiplet determined in step (c) comprises the third base type followed by the next base; and
(f) repeating steps (a) through (d), wherein the nucleotide cognate of the fourth base type comprises a reversible terminator, and wherein nucleotide cognates of the first, second and third base types are extendable, and wherein the base multiplet determined in step (c) comprises the fourth base type followed by the next base;
thereby determining four series of base multiplets in the template nucleic acid.