Patent ID: 11931350
Assignee: TREVENA, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 9:
10. The compound of claim 1, wherein the compound has a formula of:, wherein:
A2 is selected from the group consisting of CH2, CHR5 and CR5R6;
A4 is elected from the group consisting of CH2, CHR9, CR9R10 and a cycle of the formula C(CH2)n, where n=2-5;
R5, R6, R9 and R10 are independently selected from the group consisting of CH3, CH2CH3, CH2F, CHF2, CF3, n-Pr, n-Bu, i-Bu, sec-Bu, i-Pr, t-Bu and phenyl;
B3 is selected from the group consisting of H, alkyl, branched alkyl, aryl, arylalkyl, alkylcarbonyl, branched alkylcarbonyl, arylcarbonyl, alkoxycarbonyl and alkylsulfonyl;
B4 is selected from the group consisting of null, CH2, CHR19, CR19R20 and CO;
B5 is selected from the group consisting of alkyl, branched alkyl, carbocycle, carbocycle-substituted alkyl, aryl and arylalkyl; and
D1 is an optionally substituted heteroaryl.