Patent ID: 11905322
Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An isolated mutant programmed cell death 1 (PD-1) polypeptide comprising (i) SEQ ID NO: 2, (ii) SEQ ID NO: 3, or (iii) an amino acid sequence having at least 99% identity to SEQ ID NO: 2 or SEQ ID NO: 3 with the proviso that the mutant PD-1 polypeptide does not comprise SEQ ID NO: 1;
wherein the polypeptide does not comprise (i) SEQ ID NO:_2, wherein position 41 is an A and position 91 is an I, (ii) SEQ ID NO:_3, wherein position 41 is an A and position 91 is an I, or (iii) an amino acid sequence having at least 99% identity to SEQ ID NO:_2 or SEQ ID NO:_3, wherein position 41 is an A and position 91 is an I.