Patent ID: 11873303
Assignee: MERCK PATENT GMBH
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of Formula I:, or a pharmaceutically acceptable salt or stereoisomer thereof,
wherein:
X is CR or N;
Y is —NR— or —S—;
Z is CR or N;
L is:, A′ is —CRR—, —CHOH—, —C(O)—, or —NR—;
R1 is:, R2 is CF3, C(CH3)2CN, C(CH3)3, C(CH3)2CF3, C(CH3)2CH2OH, or 3-methyloxetan-3-yl; and
each R is independently hydrogen, C1-6 aliphatic, a saturated or partially unsaturated 3- to 8-membered carbocyclic ring, a 3- to 7-membered heterocyclic ring, C6-10 aryl, or a monocyclic 5- or 6-membered heteroaryl, wherein each 3- to 7-membered heterocyclic ring and 5- or 6-membered heteroaryl independently contains 1, 2, 3, or 4 heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur.