Patent ID: 11932658
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 2:
3. The compound according to claim 2 having the structure of Formula (Ia):, or a salt thereof, wherein
R1 is —CH3, —OCH3, —OCH2CH3, or —OCHF2;
R2 is F, Cl, —CN, —CH3, —CH2F, —CHF2, —CH20H, —CH(CH3)OH, or —CH═CH2;
R3a is H, —CH20H, —CH(CH3)OH, —CH2CH(CH3)OH, —CH(OH)C(CH3)3, —CH(OH)(trifluoromethyl cyclopropyl), —CH(OH)(trifluoromethyl cyclobutyl), —CH(OH)(methyl cyclohexyl), —CH2NHC(O)CH3, —CH2NHC(O)CF3, —CH2NHC(O)CH2(phenyl), —CH2NHC(O)(morpholinyl), —CH2NHC(O)OCH3, —CH2NHC(O)NH(cyclopropyl), —CH2NHC(O)NH(phenyl), —CH2NHC(O)OCH2CH3, —CH2NHC(O)OC(CH3)3, —CH2NHC(O)OCH2CH(CH3)2, —CH2NHC(O)OCH2C(CH3)3, —CH2NHC(O)OCH2CH2F, —CH2NHC(O)OCH2CF3, —CH2NHC(O)OCH2CH2OCH3, —CH2NHS(O)2CH3, —CH2O(methyl pyrimidinyl), —CH2OC(O)(dimethylaminopyridinyl), —CH2OP(O)(OH)2, —C(O)OCH3, —CH2NHC(O)ORx, —CH2NHC(O)OCH2Rx, or —CH2OC(O)NHRx;
Rx is phenyl, pyridinyl, pyridazinyl, pyrimidinyl, benzo[d]oxazolyl, benzo[d]thiazolyl, pyrrolopyridinyl, tetrahydroisoquinolinyl, tetrahydrofuranyl, tetrahydropyranyl, imidazopyridinyl, or oxo-dihydrobenzo[d]oxazolyl, each substituted with zero to two substituents independently selected from F, Cl, Br, —CN, —OH, —CH3, —CF3, —CH2CH20H, C1-2 alkoxy, phenoxy, —NRaRa, —C(O)NRaRa, —C(O)OCH3, —C(O)OC(CH3)3, —C(O)(morpholinyl), —CH(OH)CH20H, —OCH2CH20H, —OCH2CF20H, —OCH2CH(CH3)OH, —CH═CH2, —NHC(O)CH3, —OCH2CH2N(CH3)2, isoxazolyl, phenoxy, phenyl, pyrrolidinyl, thiophenyl, and methyl triazolyl; and
R3b is H, F, Cl, —CH3, or —CHF2.