Patent ID: 11964028
Assignee: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  B | IPC A  B  C

Claim 19:
20. The method of claim 1, wherein the RNA dendrimer molecule further comprises an oligonucleotide having at least 90% identity to nucleotide sequences of at least one of:
3WJ-a: UUG CCA UGU GUA UGU GGG (SEQ ID NO: 1)
3WJ-b: CCC ACA UAC UUU GUU GAU CC (SEQ ID NO: 2)
3WJ-c: GGA UCA AUC AUG GCA A (SEQ ID NO: 3)
3WJ-a_rev: GGG UGU AUG UGU ACC GUU (SEQ ID NO: 4)
3WJ-b_rev: CCU AGU UGU UUC AUA CAC CC (SEQ ID NO: 5)
3WJ-c_rev: AAC GGU ACU AAC UAG G (SEQ ID NO: 6)
3WJ-c-folate: GGA UCA AUC AUG GCA A—folate (SEQ ID NO: 7)
SquareA: GGG AGC CGU CAA UCA UGG CAA GUG UCC GCC AUA CUU UGU UGC ACG CAC (SEQ ID NO: 8)
SquareB: GGG AGC GUG CAA UCA UGG CAA GCG CAU CGC AUA CUU UGU UGC GAC CUA (SEQ ID NO: 9)
SquareC: GGG AGG UCG CAA UCA UGG CAA CGA UAG AGC AUA CUU UGU UGG CUG GAG (SEQ ID NO: 10)
SquareD: GGG ACC AGC CAA UCA UGG CAA UAU ACA CGC AUA CUU UGU UGA CGG CGG (SEQ ID NO: 11)
b-SquareA: GGC CCA CAU ACU UUG UUG AUC CAU GGU GCG UAG GGU CGU CAA UCA UGG CAA GUG UCC GCC AUA CUU UGU UGC ACU CCC UUG CUC AUC A (SEQ ID NO: 13)
b-SquareB: GGC CCA CAU ACU UUG UUG AUC CUG AUG AGC AAG GGA GUG CAA UCA UGG CAA GCG UAU CGC AUA CUU UGU UGA GAA CCC UAU GUG ACU U (SEQ ID NO: 14)
b-SquareC: GGC CCA CAU ACU UUG UUG AUC CAA GUC ACA UAG GGU UCG CAA UCA UGG CAA CGA UAG AGC AUA CUU UGU UGG AGU CCC UUA GAG UAG A (SEQ ID NO: 15)
b-SquareD: GGC CCA CAU ACU UUG UUG AUC CUC UAC UCU AAG GGA CUC CAA UCA UGG CAA UAU ACA CGC AUA CUU UGU UGA CGA CCC UAC GCA CCA U (SEQ ID NO: 16)
3WJ-a-b_rev: UUG CCA UGU GUA UGU GGG CCU AGU UGU UUC AUA CAC CC (SEQ ID NO: 17)
3WJ-c-b_rev: GGA UCA AUC AUG GCA A CCU AGU UGU UUC AUA CAC CC (SEQ ID NO: 18)
3WJ-b-a_rev: CCC ACA UAC UUU GUU GAU CC GGG UGU AUG UGU ACC GUU (SEQ ID NO: 19) or
3WJ-b-c_rev: CCC ACA UAC UUU GUU GAU CC AAC GGU ACU AAC UAG G (SEQ ID NO: 20).