Patent ID: 11919868
Assignee: RECURSION PHARMACEUTICALS, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 10:
11. A compound which is represented by Formula (II):, , wherein
Y1, Y2, and X3 are each independently CR2, or N, provided that at least one Y1, Y2, and Y3 is N; X4 and X5 are each independently C(H) or N;
m is an integer of 0, 1, or 2;
Z is a 6- to 10-membered aryl or, 5- to 10-membered heteroaryl containing 1 to 3 heteroatoms independently selected from N, O, and S;
R1 and R2 are each independently hydrogen, halo, cyano, hydroxyl, amino, C1-6 alkyl, alkylamino, haloalkyl, hydroxyalkyl, aminoalkyl, alkoxyalkyl, haloalkoxyalkyl, alkoxy, or haloalkoxy;
R3 and R4 are each independently hydrogen, C1-6 alkyl, alkylamino, haloalkyl, alkoxy, or haloalkoxy, 6- to 10-membered aryl, 5- to 10-membered heteroaryl containing 1 to 3 heteroatoms independently selected from N, O, and S, 3- to 10-membered carbocyclyl, or 4- to 10-membered heterocyclyl containing 1 to 3 heteroatoms independently selected from N, O, and S, wherein the aryl, heteroaryl, carbocyclyl, and heterocyclyl are independently substituted with 0 to 5 R5; and
R5 is hydrogen, halo, cyano, hydroxyl, amino, C1-6 alkyl, alkylamino, haloalkyl, hydroxyalkyl, hydroxycycloalkyl, aminoalkyl, alkoxyalkyl, haloalkoxyalkyl, alkoxy, haloalkoxy or —C(O)OR6; and
R6 is hydrogen or C1-6 alkyl, it should be understood by one skilled in the art that the dashed circle denotes an aromatic ring formed by Y1, Y2, Y3, and the carbon atoms.