Patent ID: 11867649
Assignee: NANO HESGARSAZAN SALAMAT ARYA NCUBATION CENTER FOR MEDICAL EQUIPMENT AND DEVICES
Field: Measurement (Instruments)
Classification: CPC G  B | IPC B  G

Claim 0:
1. A method for detecting cancerous status of a biological sample, comprising:
growing an array of hydrophobic conductive nanostructures on three-integrated electrodes patterned on a catalyst layer deposited on a substrate, the hydrophobic conductive nanostructures comprising vertically aligned multi-walled carbon nanotubes (VAMWCNTs);
putting lipid secretion of a biological sample in direct contact with the array of hydrophobic conductive nanostructures by dropping peripheral aqueous media of the biological sample on the array of hydrophobic conductive nanostructures grown on the three-integrated electrodes, the biological sample comprising a biological sample suspected to be cancerous, the peripheral aqueous media of the biological sample comprising the lipid secretion of the biological sample;
recording an electrochemical impedance spectroscopy (EIS) associated with the lipid secretion of the biological sample from the dropped peripheral aqueous media of the biological sample on the array of hydrophobic conductive nanostructures at an AC voltage between 5 mV and 10 mV by sweeping a plurality of frequency values between 0.01 Hz and 100 kHz, the EIS comprising a semicircular curve;
calculating a charge transfer resistance (Rct) of the recorded EIS by measuring a diameter of the semicircular curve; and
detecting a cancerous state for the biological sample, comprising:
detecting a cancerous state for the biological sample if the calculated Rct is equal to or more than a threshold value of 10 KΩ; or
detecting a normal state for the biological sample if the calculated Rct is less than the threshold value of 10 KΩ.