Patent ID: 11965183
Assignee: OXFORD NANOPORE TECHNOLOGIES PLC
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 11:
12. The method of claim 1, wherein
histidine (H) is substituted with arginine (R), lysine (K), glutamine (Q), asparagine (N), phenylalanine (F), tyrosine (Y) or tryptophan (W);
asparagine (N) is substituted with arginine (R), lysine (K), glutamine (Q), histidine (H), phenylalanine (F), tyrosine (Y) or tryptophan (W);
proline (P) is substituted with arginine (R), lysine (K), glutamine (Q), asparagine (N), threonine (T), histidine (H), tyrosine (Y), phenylalanine (F), tryptophan (W), leucine (L), valine (V), or isoleucine (I);
phenylalanine (F) is substituted with arginine (R), lysine (K), histidine (H), tyrosine (Y) or tryptophan (W);
aspartic acid (D) is substituted with arginine (R), lysine (K), glutamine (Q), asparagine (N), histidine (H), phenylalanine (F), tyrosine (Y) or tryptophan (W);
valine (V) is substituted with arginine (R), or lysine (K), glutamine (Q), asparagine (N), histidine (H), phenylalanine (F), tyrosine (Y), tryptophan (W), isoleucine (I) or leucine (L);
serine (S) is substituted with arginine (R), or lysine (K), glutamine (Q), asparagine (N), histidine (H), phenylalanine (F), tyrosine (Y), tryptophan (W), isoleucine (I) or leucine (L); and/or
tyrosine (Y) is substituted with arginine (R), lysine (K) or tryptophan (W).