Patent ID: 11938222
Assignee: BEIJING TIDE PHARMACEUTICAL CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A pregabalin sustained release tablet comprising a pregabalin sustained release composition, wherein, based on the total weight of the pregabalin sustained release composition, the pregabalin sustained release composition comprises:
(a) 25%-35% by weight of an active ingredient;
(b) 15%-30% by weight of a matrix-forming agent;
(c) 9%-29% by weight of a swelling agent;
(d) 4%-14% by weight of a gelling agent; and
(e) 15%-30% by weight of a filler;
wherein, the active ingredient is pregabalin or a pharmaceutically acceptable salt or hydrate thereof,
the swelling agent is polyoxyethylene,
the filler is microcrystalline cellulose, or pregelatinized starch, or a combination thereof,
the matrix-forming agent is a mixture of polyvinyl acetate and polyvinylpyrrolidone, and
the gelling agent is carbomer, and
the pregabalin sustained release tablet has a rigidity of 1909 gram force per millimeter or more at 6 hour after being subjected to a dissolution.