Patent ID: 11866391
Assignee: PTC INNOVATIONS, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 19:
20. A method of making a compound of claim 1, the method comprising:
contacting a compound of formula 8k:, R4=Alkyl,
R5═O-Alkyl, and
Alkyl═alphatic C1-C4 alkyl;

with bromoacetyl bromide to produce a compound of formula 9k:, contacting 2-fluoro-3-chloroaniline with a β-haloamine of formula 12k:, X is halogen,
R2 is H or Me, and
R3 is H or Me,

in the presence of a base to form a compound of formula 11k:, contacting the compound of formula 9k with the compound of formula 11k in the presence of a base to form the compound of claim 1.