Patent ID: 11944778
Assignee: CANON U.S.A., INC.
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 12:
13. The method of claim 12, further comprising one or more of the following:
(i) subtracting every subsequent frame region of interest (ROI) data from the reference region of interest (ROI), the region of interest (ROI) shown or as in the reference frame being used as a reference region of interest (ROI) and values from the reference frame being indicative of a possible preclearing image;
(ii) subtracting every subsequent frame region of interest (ROI) data from the reference region of interest (ROI) such that substantially similar features or the same features are substantially subtracted or are subtracted from each other, the region of interest (ROI) shown or as in the reference frame being used as a reference region of interest (ROI) and values from the reference frame being indicative of a possible preclearing image;
(iii) calculating or determining the clearance metric to be one or more of the following: a sum or mean value for 8-bit unsigned integer values in the region of interest (ROI) of all subsequent frames, a sum or mean value for 8-bit unsigned integer intensity values in region of interest (ROI) data of all subsequent frames subtracted from a reference region of interest (ROI) the region of interest (ROI) shown or as in the reference frame being used as the reference region of interest (ROI) and values from the reference frame being indicative of a possible preclearing image such that the subtraction produces a resultant signal, a sum or mean value for 8-bit unsigned integer intensity values in region of interest (ROI) data of all subsequent frames subtracted from a reference region of interest (ROI) then divided by a mean of a current frame region of interest (ROI) in the region of interest (ROI) shown or as in the reference frame is being used as the reference region of interest (ROI) and values from the reference frame being indicative of a possible preclearing image such that the subtraction produces a resultant signal, a sum or mean value for 8-bit unsigned integer intensity values in region of interest (ROI) data of all subsequent frames subtracted from a reference region of interest (ROI) then divided by a mean of the reference ROI-region of interest (ROI) region of interest (ROI) shown or as in the reference frame being used as the reference region of interest (ROI) and values from the reference frame being indicative of a possible preclearing image such that the subtraction produces a resultant signal, a mean region of interest (ROI) value of a resultant signal generated by subtracting region of interest (ROI) data of one or more frames from a reference region of interest (ROI), a mean region of interest (ROI) value of a resultant signal relative to a mean region of interest (ROI) value from the region of interest (ROI) shown or as in the reference frame, a mean region of interest (ROI) value of a resultant signal generated by subtracting region of interest (ROI) data of one or more frames from a reference frame relative to a mean region of interest (ROI) value from a region of interest (ROI) value of a current frame, a region with a large or a highest change, and/or one or more regions to be compared with one or more thresholds; and/or
(iv) detecting a pre-blood clearance state existing before blood is cleared or partially cleared and/or a post-blood clearance state existing after blood is cleared or partially cleared such that the detection of the pre-blood clearance state and/or the detection of the post-blood clearance state is/are used as additional data to calculate or determine the clearance metric more efficiently or accurately as compared to not using the additional data.