Patent ID: 11883367
Assignee: JANSSEN PHARMACEUTICA NV
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 15:
16. The compound according to claim 1, wherein
R1 represents hydrogen;
R2 represents hydrogen;
Y represents —CH2—;
Z represents —X—CR5aR5b— or —CH2CH2—
R5a and R5b each independently represent hydrogen or C1-4alkyl;
X represents —O—, —S—, or —NR1—;
R11 represents hydrogen;
Ar represents, Ar is optionally substituted with one or two substituents each independently selected from the group consisting of halo, —OH, —NH2, —NH—C1-4alkyl, —N(C1-4alkyl)2, cyano, —CF3, —C(═O)—NH—C1-4alkyl, —C(═O)—C1-4alkyl, C1-4alkyloxy, and C1-4alkyl optionally substituted with one —NR10aR10b;
Het represents a bicyclic aromatic heterocyclic ring system selected from the group consisting of (a-1);
R3a represents hydrogen, halo, —NR7aR7b, or —O—C1-4alkyl;
R7a represents hydrogen;
R7b represents hydrogen;
R4a represents hydrogen, halo, —NR8aR8b, or C1-4alkyl;
R8a and R8b each independently represent hydrogen or C1-4alkyl;
Q1 represents CR6a;
Q2 represents CR6b;
R6a and R6b each independently represent hydrogen, halogen, C1-4alkyl, —NR9aR9b, or C1-4alkyl substituted with one, two or three halo atoms;
R9a and R9b each independently represent hydrogen or C1-4alkyl.