Patent ID: 11920174
Assignee: CUREVAC SE
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C  G

Claim 11:
12. The method of claim 1, wherein step d) comprises determining the length of a homopolymeric element in the RNA molecules by using formula 5:

lxm=n(X)/n(RNA)−[u(X)−lxe],, wherein lxm is the calculated average length of the poly(X) stretch, n(X) is the measured content of a nucleoside X forming the homopolymeric element in the sample, n(RNA) is the number of copies of the RNA molecules in the sample, u(X) is the number of X in the expected sequence of the RNA molecules, lxe is the expected average length of the poly(X) stretch in the RNA molecules.