Patent ID: 11869630
Assignee: CONGENICA LTD.
Field: Computer technology (Electrical engineering)
Classification: CPC G | IPC G

Claim 17:
18. The method of using a screening system of claim 17, wherein the screening system includes a wet-laboratory arrangement for processing the biological sample as a blood sample to determine cell-free DNA readout data from the blood sample and a data processing arrangement for processing the cell-free DNA readout data with reference to information stored in a database arrangement to generate a risk score indicative of whether or not there are genetic abnormalities in the blood sample that are indicative of fetal abnormalities, wherein the method includes:
using the wet-laboratory arrangement for:
ligating nucleic acid base molecular barcodes to fragments of the cell-free DNA present in the blood sample;
amplifying the molecular barcode-ligated fragments; and
sequencing the amplified molecular barcode-ligated fragments to generate the cell-free DNA readout data.