Patent ID: 11932708
Assignee: MOCHIDA PHARMACEUTICAL CO., LTD.
Field: Medical technology (Instruments)
Classification: CPC C  A | IPC A  C

Claim 2:
3. A crosslinked alginic acid comprising both chemical crosslinking by triazole rings formed by a Huisgen reaction and ionic crosslinking partially formed by crosslinking with divalent metal ions, wherein the chemical crosslinking is obtained by mixing an alginic acid derivative of formula (I) with an alginic acid derivative of formula (II) and performing a Huisgen reaction; and
wherein in formula (I):, , (ALG) is alginic acid; —NHCO— is an amide bond via any carboxyl group of alginic acid; -L1- is a divalent linker selected from the group consisting of the following partial structural formula excluding the parts outside the cutting lines at both ends of each formula:, , and Akn is a cyclic alkyne group selected from the group consisting of the following partial structural formula, excluding the part to the right of the cutting line in each formula:, , in which the asterisks are chiral centers; in formula (II):, (ALG) is alginic acid; —NHCO— is an amide bond via any carboxyl group of alginic acid; and -L2- is a divalent linker selected from the group consisting of the following partial structural formula, excluding the parts outside the cutting lines at both ends of each formula:,