Patent ID: 11919904
Assignee: INCYTE CORPORATION
Field: Measurement (Instruments)
Classification: CPC C  A  G | IPC A  C  G

Claim 22:
23. The compound of claim 1, selected from:
4-((7′-(2-methylcyclopentyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N—((R)-1-methylpiperidin-3-yl) benzenesulfonamide;
4-((7′-((1R,3R)-3-hydroxycyclohexyl)-6′-oxo-6′,7′-dihydrospiro [cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-methylbenzene sulfonamide;
4-((7′-((1R,3R)-3-hydroxycyclohexyl)-6′-oxo-6′,7′-dihydrospiro[cyclopro pane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-(methyl-d3)benzenesulfonamide;
(S)-4-((7′-(1-cyclopropylethyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-(methyl-d3)benzenesulfonamide;
4-((7′-((trans)-2-hydroxy-2-methylcyclopentyl)-6′-oxo-6′,7′-dihydrospiro [cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-(methyl-d3)benzene sulfonamide;
4-((7′-(2-hydroxy-2-methylcyclopentyl)-6′-oxo-6′,7′-dihydrospiro [cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-(2-hydroxy-2-methylpropyl)benzenesulfonamide;
3-fluoro-4-((7′-((trans)-2-hydroxy-2-methylcyclopentyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-methylbenzenesulfonamide;
4-((7′-(2-chloro-5-fluorophenyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-(2-(dimethylamino)ethyl)benzenesulfonamide;
4-((7′-(7-chloro-1,2,3,4-tetrahydroisoquinolin-6-yl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-methylbenzenesulfonamide;
4-((7′-(5-fluoro-2-methylphenyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-methylbenzenesulfonamide; and
4-((7′-(2-chloro-5-fluorophenyl)-6′-oxo-6′,7′-dihydrospiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-2′-yl)amino)-N-methylbenzenesulfonamide;
or a pharmaceutically acceptable salt thereof.