Patent ID: 11857577
Assignee: LABYRINTH HOLDINGS, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A

Claim 0:
1. A liquid formulation comprising:
(a) a lysate and/or cell wall extract from a Gram-positive bacterium comprising a toll-like receptor (TLR) ligand that activates at least one or more TLRs or Nod-like receptors (NLRs), or a pharmaceutically acceptable salt thereof; and
(b) a buffer;
wherein the liquid formulation comprises a promoter;
wherein the promoter is selected from the group consisting of amino acids, amino sugars, and sugars; and
wherein the promoter is selected from the group consisting of poly-L-lysine, glucosamine, poly-L-arginine, galactosamine, N-acetylmannosamine (NAM; N-Ac-Man), N-acetylglucosamine (NAG; N-Ac-Glc), N,N′-diacetylglucosamine (NAG-NAG; N,N′-diacetylchitobiose), N,N′,N″,N′″-tetraacetylglucosamine (NAG-NAG-NAG-NAG; N,N′,N″,N′″-tetraacetylchitotetraose), and mixtures thereof.