Patent ID: 11932696
Assignee: SHIONOGI & CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 0:
1. A method for treating a solid cancer in a patient having cancer, said method comprising:
administering to the patient a therapeutically effective amount of an IgG antibody against CCR8 having antibody-dependent cell-mediated cytotoxicity (ADCC) activity against cells expressing CCR8,
wherein the antibody against CCR8 binds to CCR8 on tumor infiltrating Treg cells or tumor infiltrating macrophage cells, and removes these cells by the ADCC activity of this antibody,
in the administering step, the only antibody administered is the IgG antibody against CCR8,
the IgG antibody against CCR8 is a CCR8-neutralizing antibody, and
the solid cancer excludes CCR8+cancer cells.