Patent ID: 11878059
Assignee: UNIVERSITY OF ULSTER
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 0:
1. A microbubble complex which comprises a microbubble attached to a plurality of linking groups, each linking group having three branches wherein a first branch of the linking group is bound to the microbubble, a second branch of the linking group is linked to a chemotherapeutic agent and a third branch of the linking group is linked to a sonosensitising agent, wherein said chemotherapeutic agent is an anti-metabolite or an anthracycline, and said sonosensitising agent is selected from the group consisting of phenothiazine dyes, Rose Bengal, porphyrins, chlorins, benzochlorins, phthalocyanines, napthalocyanines, porphycenes, cyanines, azodipyromethines, acridine dyes, purpurins, pheophorbides, verdins, psoralens, hematoporphyrins, protoporphyrins and curcumins.