Patent ID: 11866772
Assignee: ROCHE MOLECULAR SYSTEMS, INC.
Field: Computer technology (Electrical engineering)
Classification: CPC C  G | IPC C  G

Claim 10:
11. The computer product of claim 1, wherein estimating the number of PCR cycles in the pre-amplification procedure is determined by:, p
    ^
   
   =
   
    
     log
     
      (
      
       1
       +
       
        y
        0
       
      
      )
     
    
    ⁢
    
     
      
       μ
       ^
      
      pc
     
     
      τ
      ⁢
      
       
        Z
        ^
       
       
        0
        ⁢
        c
       
      
      ⁢
      
       L
       c
      
     
    
   
  
  ,, where {circumflex over (μ)}pc is the minimal input number of control chromosome molecules for the dPCR experiment, τ is the pre-specified portion constraint, y0 is a lower bound for the PCR efficiency in the pre-amplification procedure, Lc is the number of loci on one or more control chromosomes and equals the number of loci on the test chromosome, and {circumflex over (Z)}0c is the minimal number of control chromosome molecules for the pre-amplification procedure.