Patent ID: 11919958
Assignee: XENCOR, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 9:
10. The heterodimeric antibody according to claim 1, wherein the CH1-hinge-CH2-CH3 of the second monomer comprises amino acid variants L368D/K370S/N208D/Q295E/N384D/Q418E/N421D/E233P/L234V/L235A/G236del/S267K,
wherein the first Fc domain comprises amino acid variants S364K/E357Q/E233P/L234V/L235A/G236del/S267K, E223P/L234V/L235A/G236del/S267K,
and wherein numbering is according to EU numbering.