Patent ID: 11919943
Assignee: THE UNIVERSITY OF BERN
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 3:
4. The antibody molecule or binding fragment thereof of claim 1 comprising one or more of the following properties:
(i) binds to BK virus serotype I VP1 with an EC50 of less than about 10 nM when the antibody molecule or binding fragment thereof is tested as a bivalent molecule using an ELISA assay;
(ii) binds to BK virus serotype II VP1 with an EC50 of less than about 10 nM when the antibody molecule or binding fragment thereof is tested as a bivalent molecule using an ELISA assay;
(iii) binds to BK virus serotype III VP1 with an EC50 of less than about 10 nM when the antibody molecule or binding fragment thereof is tested as a bivalent molecule using an ELISA assay;
(iv) binds to BK virus serotype IV VP1 with an EC50 of less than about 10 nM when the antibody molecule or binding fragment thereof is tested as a bivalent molecule using an ELISA assay;
(v) does not bind to JC virus VP1;
(vi) neutralizes BK virus serotype I;
(vii) neutralizes BK virus serotype II;
(viii) neutralizes BK virus serotype III; or
(ix) neutralizes BK virus serotype IV.