Patent ID: 11905559
Assignee: MAUMITA MANDAL
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C  G

Claim 1:
2. A biological sensor comprising:
a biological molecule not found in nature comprising one or more mutated aptamer domain, wherein the one or more mutated aptamer domain comprises: one or more hairpin; one or more loop; and one or more junction, wherein the one or more mutated aptamer domain is switchable between one or more structural conformations in response to one or more ligand binding to the one or more mutated aptamer domain,
wherein a rate in which the one or more mutant aptamer domain switches between the one or more structural conformations is faster than a rate in which one or more wild-type aptamer domain switches between the one or more structural conformations, and
wherein the one or more mutated aptamer domain comprises a sequence selected from the group consisting of: SEQ ID NOs: 2-9 of the Sequence Listing and combinations thereof.