Patent ID: 11911512
Assignee: PURDUE PHARMA L.P.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of treating pain in a subject, comprising:
administering to the subject a solid controlled release dosage form, the solid controlled release dosage form comprising:
a core comprising a first portion of an opioid analgesic dispersed in a first matrix material, wherein the opioid analgesic comprises oxycodone, a pharmaceutically acceptable salt thereof or combinations thereof; and
a shell encasing the core and comprising a second portion of the opioid analgesic dispersed in a second matrix material,
wherein the dosage form further comprises acetaminophen;
wherein the amount of opioid analgesic released from the dosage form is proportional within 20% to elapsed time from 8 to 24 hours, as measured by an in-vitro dissolution in a USP Apparatus 1 (basket) at 100 rpm in 900 ml simulated gastric fluid without enzymes (SGF) at 37° C.