Patent ID: 11908560
Assignee: ONCOHOST LTD.
Field: Medical technology (Instruments)
Classification: CPC G | IPC G

Claim 11:
12. The method of claim 11, wherein:
a. said process class is inflammation and said therapeutic agent is selected from: BMS-986253 (anti-IL-8), BNT411 (TLR7 antagonist), BDC-1001 (anti-HER2 and TLR7/8 agonis conjugate), Tocilizumab (anti-IL-6R), TransCon TLR7/8 Agonist (TLR7/8 agonist), Canakinumab (anti-IL-1 beta), and Pixatimod (TLR9 agonist);
b. said process class is proliferation and said therapeutic agent is selected from: Carboplatin, Pemetrexed, Paclitaxel, Nab-paclitaxel, Cisplatin, Carboplatin, Etoposide, FOLFOX, Datopotamab Deruxtecan (anti-TACSTD2 antibody-drug conjugate), radiotherapy, chemoradiotherapy, Stereotactic radiation, Tisotumab vedotin (anti-CD142 antibody-drug conjugate), Vistusertib (mTOR inhibitor), AZD9150 (STAT3 oligonucleotide inhibitor), Tomivosertib (MNK1/2 inhibitor), Sacituzumab Govitecan-hziy (SG, anti-TACSTD2 antibody-drug conjugate), Azacitidine+Entinostat (chemotherapy+HDAC inhibitor), brentuximab vedotin (anti-CD30 antibody-drug conjugate), ATE: Trans-arterial Tirapazamine (embolization and chemosensitizing agent), LMB-100 (antibody-Drug Conjugate targeting mesothelin), SAR408701 (Tusamitamab ravtansine, anti-CEACAM5-maytansinoid Antibody-drug Conjugate), Cryosurgical freezing, Non-ablative Cryosurgical freezing, Ipatasertib (AKT inhibitor), RO6958688 (bispecific antibody targeting CEA and CD3), Cobimetinib (MEK inhibitor), Sacituzumab Govitecan (anti-TACSTD2 antibody-drug conjugate), and 6-Thio-2′-Deoxyguanosine (telomere-disrupting compound);
c. said process class is immune modulation and said therapeutic agent is selected from: AZD6738 (ATR kinase inhibitor), Oleclumab (anti-NT5E), Olaparib (PARP inhibitor), CPI-444 (ADORA2A/B antagonist), Lifileucel, LN-145, GSK4428859A (Anti-TIGIT), GSK3359609/Feladilimab (agonstic anti-ICOS), MK-5890 (Anti-CD27 agonist), MK-0482 (LILRB4 signaling inhibitor), MK-4830 (Anti-LILRB2), Domvanalimab or AB154 (Anti-TIGIT), Etrumadenant (ADORA2A/B antagonist), Tiragolumab (anti-TIGIT), Olaparib (PARP inhibitor), Niraparib (PARP inhibitor), Relatlimab (anti-LAG3), Cobolimab (Anti-HAVCR2), Pembrolizumab/Vibostolimab (MK-7684A, Anti-TIGIT), Ociperlimab (Anti-TIGIT), Etrumadenant+Domvanalimab (ADORA2A/B antagonist+anti-TIGIT (alteranative ICI)), SEA-CD40 (Agonistic anti-CD40), Oleclumab (Anti-NT5E), Monalizumab (Anti-KLRC1), and Sitravatinib (Anti-RTKs (receptor tyrosine kinases) including TYRO3, VEGFR2 AXL, MET, FLT3, KIT, FLT1, DDR2, NTRK1, FLT4, EPHA3, PDGFRA, METRK, EPHB6, RET, KDR));
d. said process class is angiogenesis and said therapeutic agent is selected from: AL3818 (Tyrosine kinase inhibitor), Bevacizumab (anti-VEGFA), Ramucirumab (anti-KDR), Sitravatinib (Tyrosine kinase inhibitor), ATE: Trans-arterial Tirapazamine Embolization, Cabozantinib S-malate (Tyrosine kinase inhibitor), cediranib (Tyrosine kinase inhibitor), Anlotinib hydrochloride (Anti-VEGFR1, VEGFR3, VEGFR2/KDR, PDGFR-α, c-Kit, FGFR1, FGFR2, FGFR3), Endostar (Anti-bFGF,FGF-2,VEGF), Famitinib (RTK), Lenvatinib (Tyrosine kinase inhibitor), Vorolanib (Anti-PDGFRA, PDGFRB, CSF1R, KDR, FLT1, FLT4), Defactinib (Anti-PTK2, PTK2B), Nintedanib (Tyrosine kinase inhibitor), Regorafenib (Tyrosine kinase inhibitor), cabozantinib (Tyrosine kinase inhibitor), Axitinib (Tyrosine kinase inhibitor), and AL3818 or anlotinib (Tyrosine kinase inhibitor);
e. said process class is metabolism and said therapeutic agent is selected from: Linagliptin (DPP4 inhibitor), Metformin (antihyperglycemic agent), Rosiglitazone (PPARs activator), Talabostat (DPP4 inhibitor), and telaglenastat (glutaminase inhibitor); or
f. a combination thereof.