Patent ID: 11857962
Assignee: APTITUDE MEDICAL SYSTEMS, INC.
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 11:
12. A method for preparing a sample derived from a subject, comprising:
I) introducing the sample into a sample receptacle through a first open end of said sample receptable;
II) closing said first open end irreversibly by attaching a cap to said sample receptable;
III) said cap comprises a reservoir for retaining a composition, a first piercing member and a first pierceable barrier for sealing said composition within said reservoir;
wherein said cap comprises a wall defining the outer perimeter of said reservoir, wherein an outer surface of said wall is made from or is coated with an elastomeric material for sealingly engagement against an inner surface of said sample receptacle when said first open end is closed by said cap;
IV) said sample receptacle comprises one or more second piercing members;
wherein at least a portion of an interior surface of the sample receptable, configured to be in contact with said wall of the cap when the cap is closed, is made from or is coated with an elastomeric material substantially coextensive with said elastomeric material of the outer surface of the wall;
V) when the first open end of the sample receptacle is closed by said cap, said first piercing member and said one or more second piercing members effect a force to disestablish the first pierceable barrier from opposite side of said first pierceable barrier.