Patent ID: 11904020
Assignee: BICYCLETX LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 7:
8. The multimeric binding complex according to claim 7 wherein m represents 2 and CHM is a motif of formula (A):, wherein BCY represents a peptide ligand specific for TREM2 comprising a polypeptide comprising at least three reactive groups, separated by at least two loop sequences, and a molecular scaffold which forms covalent bonds with the reactive groups of the polypeptide such that at least two polypeptide loops are formed on the molecular scaffold and n represents 1 to 50, optionally wherein the multimeric binding complex is BCY18117 and BCY18119:, wherein BCY represents
a peptide ligand of SEQ ID NO: 43 comprising a molecular scaffold which is 1,1′,1″-(1,3,5-triazinane-1,3,5-triyl)triprop-2-en-1-one (TATA) and the peptide ligand comprises A-(SEQ ID NO: 1)-A-[K(PYA)] and n represents 10 (BCY18119) and 23 (BCY18117).