Patent ID: 11878975
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 13:
14. A compound according to claim 13 or a salt thereof, wherein said compound is:
1-(3-(2-(3,4-dimethoxyphenyl)-3-isopropyl-1H-indol-5-yl)-7-azabicyclo[4.1.1]octan-7-yl)-2-(dimethylamino)ethanone (279);
1-(3-(2-(3,4-dimethoxyphenyl)-3-isopropyl-1H-indol-5-yl)-7-azabicyclo[4.1.1]octan-7-yl)-2-(dimethylamino)ethanone (280);
3-(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-1H-indol-5-yl)quinuclidine (362-363);
3-(3-isopropyl-2-(8-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-indol-5-yl) quinuclidine (364-365);
8-(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-1H-indol-5-yl)-1,3-diazaspiro[4.5]decane-2,4-dione (366);
6-(3-isopropyl-5-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridine (506);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-N,N-dimethylacetamide (507);
6-(3-isopropyl-5-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-8-methoxy-[1,2,4]triazolo[1,5-a]pyridine (508);
2-(5-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-N,N-dimethylacetamide (509);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-N-methylacetamide (510);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)acetamide (511);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)acetonitrile (512);
6-(3-isopropyl-5-(2-(oxetan-3-yl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-8-methoxy-[1,2,4]triazolo[1,5-a]pyridine (513);
6-(3-isopropyl-5-(2-(2-(methylsulfonyl)ethyl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridine (514);
6-(3-isopropyl-5-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (519);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-N,N-dimethylacetamide (520);
1-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-2-(dimethylamino)ethan-1-one (521);
6-(3-isopropyl-5-(2-(oxetan-3-yl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (522);
2-(5-(2-(7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl) hexahydrocyclopenta[c]pyrrol-2(1H)-yl)acetonitrile (558);
6-(3-isopropyl-5-(2-methyloctahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (559);
6-(3-isopropyl-5-(2-isopropyloctahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (560);
6-(3-isopropyl-5-(2-((3-methyloxetan-3-yl)methyl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (561);
6-(3-isopropyl-5-(2-(tetrahydrofuran-3-yl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (562); or
6-(3-isopropyl-5-(2-(tetrahydro-2H-pyran-4-yl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-indol-2-yl)-7,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (563).