Patent ID: 11911454
Assignee: ZOETIS SERVICES LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method for inducing a protective immune response in a porcine animal against infection by a Porcine Reproductive and Respiratory Syndrome (PRRS) virus, the method comprising administering to said animal a vaccine comprising a modified live PRRS virus, and a carrier suitable for veterinary use, wherein said vaccine is administered to said animal prior to weaning; wherein said vaccine is safe and immunoprotective even if administered when said animal is no more than two weeks of age; wherein said modified live PRRS virus is prepared by attenuating a virulent PRRS virus in a permissive mammalian cell line that exogenously expresses porcine CD163 receptor protein, and recovering virus from the culture; and wherein said protective immune response provides a reduction in mortality in comparison to an unvaccinated animal infected with PRRS.