Patent ID: 11883476
Assignee: INTERVET INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A

Claim 0:
1. An immunogenic composition comprising two or more alphavirus RNA replicon particles each individually encoding one or more Borrelia burgdorferi antigens;
wherein one alphavirus RNA replicon particle encodes a Borrelia burgdorferi outer surface protein A (OspA), wherein the OspA consists of the amino acid sequence of SEQ ID NO: 2,
and wherein another alphavirus RNA replicon particle encodes a Borrelia burgdorferi outer surface protein C (OspC), wherein the OspC consists of the amino acid sequence of SEQ ID NO: 4; wherein both OspA-borreliacidal and OspC-borreliacidal antibodies are induced in a canine when said canine is immunized with said immunogenic composition.