Patent ID: 11938164
Assignee: TRUSTEES OF BOSTON UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G | IPC A

Claim 5:
6. A method of treating an overweight, obese or diabetic subject with cancer, the method comprising administering at least one CT scan to an overweight, obese or diabetic subject with cancer determined to have
(a) an expression level of at least one gene selected from: miR374a-5p, miR-93-5p, miR-28-3p, miR-let-7b-3p, TSP5, SNAI1, TWIST1, SNAI2, vimentin (VIM), E-cadherin (CDH1), ZEB1 and AHNAK in an exosome originating from the adipose tissue or adipocytes of the subject, wherein the expression level of the at least one gene is not increased relative to a reference; or
(b) an expression level of at least one gene selected from: miR424-5p, miR-326, miR-27a-3p, miR320b and miR320d in an exosome originating from the adipose tissue or adipocytes of the subject, wherein the expression level of the at least one gene is not decreased relative to a reference,
wherein the at least one CT scan is administered at a frequency of no more than one CT scan every six months.