Patent ID: 11951085
Assignee: REMEDY PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  Y | IPC A

Claim 9:
10. A method of reducing cerebral midline shift in a subject following a large hemispheric infarction, wherein the subject has a brain lesion volume of greater than 100 cc, comprising:
administering to the subject glyburide following the subject experiencing the large hemispheric infarction, wherein the administering includes a first continuous infusion and a second continuous infusion of glyburide lasting cumulatively for at least 72 hours after starting the first continuous infusion, wherein the first continuous infusion is started within 9 hours following the subject experiencing the large hemispheric infarction, wherein the method reduces the cerebral midline shift as determined over a population based on the degree of cerebral midline shift in patients treated with the continuous infusions compared to a similar population that was not treated with the continuous infusions.