Patent ID: 11954596
Assignee: NANTHEALTH, INC.
Field: Computer technology (Electrical engineering)
Classification: CPC G | IPC G

Claim 24:
25. An apparatus for determining classifications based on whole slide images (WSIs), the apparatus comprising:
a processor;
a memory device storing software instructions for determining molecular subtype classifications; and
a training engine executable on the processor according to software instructions stored in the memory device and configured to:
obtain a plurality of training WSIs;
generate a varied-size feature map for each of the plurality of training WSIs by generating a grid of patches for the training WSI, segmenting the training WSI into tissue and non-tissue areas, and converting patches comprising the tissue areas into tensors;
generate at least one bounding box based on the patches comprising the tissue areas;
segment the at least one bounding box into feature map patches;
generate a fixed-size feature map based on at least a subset of the feature map patches;
configure a classifier model to process fixed-size feature maps corresponding to the training WSIs such that, for each fixed-size feature map, the classifier model is operable to assign a WSI-level tissue or cell morphology classification or regression based on the tensors;
train the classifier model using the fixed-size feature map corresponding to the plurality of training WSIs; and
configure a classification engine to use the trained classifier model to determine a WSI-level tissue or cell morphology classification or regression for a test WSI.