Patent ID: 11958831
Assignee: ARTIVILA (SHENZHEN) INNOVATION CENTER, LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The compound or the pharmaceutically acceptable salt thereof according to claim 1, wherein the compound has a structure represented by Formula (IA):, wherein
R4 is selected from CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc;
R5 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, SO2NRbRc, alkyl, alkenyl, alkynyl, cycloalkyl, or heterocycloalkyl; wherein the alkyl, alkenyl, alkynyl, cycloalkyl, or heterocycloalkyl is unsubstituted or substituted with 1 to 3 R5a;
R5a is selected from H, D, halogen, cyano, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc; wherein the alkyl, cycloalkyl, and heterocycloalkyl are unsubstituted or substituted with 1 to 3 R5b;
R5b is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, CORd, CONRbRc, CO2Rd, SO2Rd, or SO2NRbRc;
R8 is selected from H, D, alkyl, halogen, haloalkyl, or ORa;
Ra, Rb, Rc, and Rd are each selected from H, D, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl is unsubstituted or substituted with 1 to 4 R6;
R6 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, NRbCORd, NRbCONRbRc, CONRbRc, CO2Rd, NRbSO2Rd, NRbSO2NRbRc, SORd, SO2Rd, SO2NRbRc, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl;
wherein Rb and Rc in a group containing both Rb and Rc are attached to a N atom in the group by a single bond or form a heterocycloalkyl together with the N atom to which they are attached, and the heterocycloalkyl is unsubstituted or substituted with 1 to 3 R7;
R7 is selected from H, D, halogen, cyano, ORa, SRa, NRbRc, NRbCORd, NRbCONRbRc, CONRbRc, CO2Rd, NRbSO2Rd, NRbSO2NRbRc, SORd, SO2Rd, SO2NRbRc, alkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and
z is 1 or 2.