Patent ID: 11958813
Assignee: JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 6:
7. A method for preparing a uracil compound containing a carboxylate fragment, a structure of the uracil compound containing the carboxylate fragment is shown in a formula (I):, wherein the method comprises a contact reaction between a carboxylic acid compound shown in a formula (II) and different substituted alcohol, halogenated, or sulfonate compounds in a presence of a solvent,, wherein in the general formulas (I) and (II):
R1 and R2 are each selected from hydrogen or methyl; or the R1, the R2, and a carbon atom attached to the R1 and the R2 form a 3-membered carbocycle;
R3 is selected from C1-3 alkoxy C1-3 alkyl, C1-3 haloalkoxy C1-3 alkyl, C2-6 alkenoxy C1-3 alkyl, C2-6 haloalkenoxy C1-3 alkyl, C2-6 alkynoxy C1-3 alkyl, C2-6 haloalkynoxy C1-3 alkyl, C1-3 alkyl S(O)n C1-3 alkyl, C3-6 oxygen-containing cycloalkyl C1-3 alkyl, or C3-9 oxygen-containing cycloalkyl;
n=0, 1, or 2; and
when the R1 is hydrogen and the R2 is methyl, a chiral carbon atom connected to the R1 and the R2 is selected from either an R configuration or an S configuration, or a mixture of the R configuration and the S configuration; and in the mixture, a ratio of the R configuration to the S configuration is 1:99 to 99:1.