Patent ID: 11904052
Assignee: ARBUTUS BIOPHARMA CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of ameliorating an infusion reaction associated with intravenous administration of at least one lipid formulated therapeutic agent in a mammal in need thereof, comprising administering to the mammal via injection a therapeutically effective amount of a nonsteroidal anti-inflammatory (NSAID) in combination with the lipid formulated therapeutic agent being intravenously administered, wherein the NSAID is ketorolac, wherein the lipid formulated therapeutic agent is formulated in a lipid nanoparticle (LNP), which LNP comprises the lipid formulated therapeutic agent, a cationic lipid, and a non-cationic lipid, and wherein the lipid formulated therapeutic agent is a nucleic acid, a polypeptide or an organic compound.