Patent ID: 11857647
Assignee: JUBILANT DRAXIMAGE INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 17:
18. A liquid radiopharmaceutical composition consisting of:
a first component consisting of a saline solution of 99mTc pertechnetate and water; and
a second component consisting of (i) tetrofosmin disulfosalicylate in an amount between about 13.0-15.0% (w/w) of the second component; (ii) gentisic acid in an amount between about 13.54-18.03% (w/w) of the second component; (iii) stannous chloride dihydrate in an amount between about 0.37-0.5% (w/w) of the second component; (iv) a transchelator in an amount between about 12.0-16.0% (w/w) of the second component; and (v) sodium bicarbonate at an amount between about 50.0-60.0% (w/w) of the second component,
wherein the tetrofosmin disulfosalicylate and stannous chloride dihydrate are present in a ratio by weight of about 30:1 to about 35:1,
wherein the liquid radiopharmaceutical composition is free of ascorbate or ascorbic acid and an antimicrobial preservative, and has a radiochemical purity of at least 90% after 12 hours of storage at a temperature of 2-30° C.