Patent ID: 11872277
Assignee: THE SCRIPPS RESEARCH INSTITUTE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 29:
30. The polynucleotide of claim 29, encoding (1) a fusion polypeptide sequence that comprises from N-terminus to C-terminus (a) the engineered Ebolavirus GP protein shown in SEQ ID NO:17, nanoparticle subunit sequence shown in SEQ ID NO:36 (E2p), locking domain shown in SEQ ID NO:39 (LD4), and T cell epitope shown in SEQ ID NO:31 or (b) the engineered Ebolavirus GP protein shown in SEQ ID NO:17, nanoparticle sequence shown in SEQ ID NO:37 (I3-01v9), locking domain shown in SEQ ID NO:40 (LD7), or (2) a variant of the fusion polypeptide sequence with at least 99% sequence identity.