Patent ID: 11944644
Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 14:
15. The DNA construct according to claim 14, characterized by at least one of:
(i) the self-cleaving peptide has the amino acid sequence of SEQ ID NO: 26;
(ii) the leader peptide has the amino acid sequence of SEQ ID NO: 20;
(iii) the activation domain has the amino acid sequence of SEQ ID NO: 23;
(iv) the costimulatory domain has the amino acid sequence of SEQ ID NO: 22;
(v) the anti-CD138 scFv domain has the amino acid sequence of SEQ ID NO: 18;
(vi) the anti-CD38 scFv domain has the amino acid sequence of SEQ ID NO: 19;
(vii) the self-cleaving peptide is encoded by the DNA sequence of SEQ ID NO: 27;
(viii) the leader peptide is encoded by the DNA sequence of SEQ ID NO: 39;
(ix) the activation domain is encoded by the DNA sequence of SEQ ID NO: 31;
(x) the costimulatory domain is encoded by the DNA sequence of SEQ ID NO: 30;
(xi) the anti-CD138 scFv domain is encoded by the DNA sequence of SEQ ID NO: 28; and
(xii) the anti-CD38 scFv domain is encoded by the DNA sequence of SEQ ID NO: 29.