Patent ID: 11939302
Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 4:
5. The method of claim 1, wherein the compound is of formula (III):, wherein:
R is selected from the group consisting of —H and C1-C6-alkyl;
each R1 is independently selected from the group consisting of —H, halogen, C1-C6-alkyl, substituted C1-C6-alkyl, C3-C6-cycloalkyl, substituted C3-C6-cycloalkyl, —OR2, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl;
each R2 is independently selected from the group consisting of —H, and C1-C6-alkyl;
each W is selected from the group consisting of —CH2—, —CHR3— and —CR3R4—;
R3 and R4 are independently selected from the group consisting of halogen, C1-C6-alkyl, substituted C1-C6-alkyl, C3-C6-cycloalkyl, substituted C3-C6-cycloalkyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, fused-heterocycle, and substituted fused-heterocycle, or together R3 and R4 comprise a carbocycle, substituted carbocycle or oxo;
m is selected from 1, 2 or 3;
Z is selected from the group consisting of —OR5, halogen, —NR5R5, —NHC(═O)R5, —NHC(═O)NR5R5, aryl, and heteroaryl; and
each R5 is independently selected from the group consisting of —H, C1-C6-alkyl, substituted C1-C6-alkyl, aryl, substituted aryl, heteroaryl, and substituted heteroaryl;
or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, a mixture of two or more tautomers, or an isotopic variant thereof;
or a pharmaceutically acceptable salt, solvate, or hydrate thereof.