Patent ID: 11958844
Assignee: CHONG KUN DANG PHARMACEUTICAL CORP.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC C

Claim 2:
3. The 1,3,4-oxadiazole derivative compound represented by the formula I, optical isomer thereof or pharmaceutically acceptable salt thereof according to claim 1, wherein:
X, Y and Z are each independently CR3;
L is —(C1-C4 alkylene)-, —(C2-C4 alkenylene)-, —(C═O)—(C1-C2 alkylene)-, —(C═O)O—(C1-C2 alkylene)-, —(C═O)NH—(C1-C2 alkylene)-, —O(C═O)—(C1-C2 alkylene)- or a single bond, wherein at least one H of —(C1-C4 alkylene)-, —(C2-C4 alkenylene)-, —(C═O)—(C1-C2 alkylene)-, —(C═O)O—(C1-C2 alkylene)-, —(C═O)NH—(C1-C2 alkylene)- and —O(C═O)—(C1-C2 alkylene)- may be substituted with aryl;
R1 is —C1-C6 alkyl, —C2-C6 alkenyl,, benzyl, phenyl, naphthyl,, or —NR4R5, wherein at least one H of phenyl, naphythyl,, may be substituted with —C1-C6 alkyl, —C1-C6 alkoxy, halo, nitro, —CF3 or —S(═O)2—R9;
R2 is —CF2H or —CF3;
R3 is hydrogen;
R4 to R5 are each independently —C1-C4 alkyl; and
R9 is each independently —C1-C4 alkyl.