Patent ID: 11918613
Assignee: FERRING B.V.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A pharmaceutical composition comprising bacteriophages capable of producing a lytic infection in an adherent-invasive Escherichia coli strain, wherein the composition comprises:
(a) bacteriophages of strain P2 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM 1-4695, or a variant thereof, wherein the variant has the same lytic activity and at least 80% sequence identity on at least 70% of length as said deposited bacteriophage strain P2;
(b) bacteriophages of strain P8 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM 1-4700, or a variant thereof, wherein the variant has the same lytic activity and at least 80% sequence identity on at least 70% of length as said deposited bacteriophage strain P8;
(c) bacteriophages of strain CLB P2 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM 1-4675 or a variant thereof, wherein the variant has the same lytic activity as said deposited bacteriophage strain CLB P2, and
(d) a pharmaceutically acceptable carrier comprising one or more pharmaceutically acceptable auxiliary agents selected from matrix-forming agents, thickeners, binders, lubricants, pH adjusting agents, protecting agents, viscosity enhancers, wicking agents, disintegrants, surfactants, anti-oxidants, wetting agents, colorants, flavoring agents, taste-masking agents, sweeteners, and preservatives.