Patent ID: 11945810
Assignee: ECSTASY LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A compound selected from compounds having one of the following formulae or a pharmaceutically acceptable salt thereof, wherein, unless otherwise indicated, each chiral compound below is in either the R or the S configuration:, Com-

pound

No.
Structure
Name

6

2-methyl-5-(2-((3R  or S)-3-phenethyl-3- (tetrahydrofuran-2- yl)pyrrolidin-1- yl)propan-2- yl)pyridine citrate

 

44

(R or S)-(3-(4- fluorophenethyl)- 1-(pyridin-3- ylmethyl)- pyrrolidin-3- yl)methanol citrate

 

45

(R or S)-3-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)-5- fluoropyridine  citrate

 

46

(R or S)-3-(2-(3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)ethyl)pyridine

 

47

(R or S)-3-(2-(3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)ethyl)pyridine

 

48

(R or S)-3,3′-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)-pyrrolidin-1- yl)methylene)- dipyridine

 

49

(R or S)-N-(3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)pyridin-3-amine

 

50

3-(1-((R or S)-3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1-yl)-2,2,2- trifluoroethyl)- pyridine

 

51

(R or S)-3,5- dichloro-4-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)pyridine

 

52

(R or S)-4-(2-(3- (ethoxymethyl)-1- (pyridin-3- ylmethyl)- pyrrolidin-3-yl)- ethyl)benzonitrile

 

53

(R or S)-3-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)- isonicotinonitrile

 

54

(R or S)-3-((3- (ethoxymethyl)- 3-(4- fluorophenethyl) pyrrolidin-1- yl)methyl)- picolinonitrile

 

55

(R or S)-5-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)-2- methoxypyridine

 

56

(R or S)-5-((3- (ethoxymethyl)- 3-(4- fluorophenethyl) pyrrolidin-1- yl)methyl)-2- methoxyisonico- tinonitrile

 

57

(R or S)-3-((3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)- picolinamide

 

60

(R or S)-4-(2-(l- (di(pyridin-3- yl)methyl)-3- (ethoxymethyl)- pyrrolidin-3- yl)ethyl)- benzonitrile

 

61

(R or S)-2-(3- (ethoxymethyl)- 3-(4- fluorophenethyl) pyrrolidin-1-yl)- 1-(6- methylpyridin-3- yl)ethan-1-one

 

62

(R or S)-2-(3- (ethoxymethyl)- 3-(4- fluorophenethyl)- pyrrolidin-1-yl)-2- methyl-1-(6- methylpyridin-3- yl)propan-1-one

 

65

(R or S)-4-(2-(3- (oxetan-3-yl)-1- (pyridin-3- ylmethyl)- pyrrolidin-3- yl)ethyl)- benzonitrile

 

66

(R or S)-3-((3-(4- fluorophenethyl)- 3-(oxetan-3- yl)pyrrolidin-1- yl)methyl)pyridine

 

67

(R or S)-4-(2-(1- (2-(6- methylpyridin-3- yl)propan-2-yl)- 3-(oxetan-3- yl)pyrrolidin-3- yl)ethyl)- benzonitrile

 

68

(R or S)5-(3- (3-(4- fluorophenethyl)- 3-(oxetan-3- yl)pyrrolidin-1- yl)oxetan-3- yl)-2- methylpyridine

 

72

(R or S)-5-(2- (3-(2-ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-3-(4- fluorophenethyl) pyrrolidin-1- yl)propan- 2-yl)-2- methylpyridine

 

73

(R or S)-5-(2- (3-(4-fluorophenethyl)- 3-(1,1,1,3,3,3- hexafluoro-2- methoxypropan- 2-yl)pyrrolidin- 1-yl)propan- 2-yl)-2-methylpyridine

 

74

(R or S)- 1,1,1,3,3,3-hexafluoro- 2-(3-(4- fluorophenethyl)- 1-(2-(6- methylpyridin- 3-yl)propan-2- yl)pyrrolidin-3- yl)propan-2-ol

 

75

(R or S)-5- ((3-(2-ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)-2- methylpyridine

 

76

(R or S)-3-((3-(2- ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-3-(4- fluorophenethyl)- pyrrolidin-1- yl)methyl)pyridine

 

77

(R or S)-4-(2- (3-(2-ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-1-(2-(6- methylpyridin-3- yl)propan-2- yl)pyrrolidin-3- yl)ethyl)- benzonitrile 

 

78

(R or S)-4-(2-(3- (1,1,1,3,3,3- hexafluoro- 2-methoxypropan- 2-yl)-1-(2-(6- methylpyridin-3- yl)propan-2- yl)pyrrolidin-3- yl)ethyl)- benzonitrile 

 

79

(R or S)-4-(2-(3- (1,1,1,3,3,3- hexafluoro-2- hydroxypropan- 2-yl)-1-(2-(6- methylpyridin- 3-yl)propan-2- yl)pyrrolidin-3- yl)ethyl)- benzonitrile 

 

80

(R or S)-4- (2-(3-(2-ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-1-((6- methylpyridin- 3-yl)methyl)- pyrrolidin-3- yl)ethyl)- benzonitrile

 

81

(R or S)-4-(2- (3-(2-ethoxy- 1,1,1,3,3,3- hexafluoropropan- 2-yl)-1-(pyridin- 3-ylmethyl)- pyrrolidin-3- yl)ethyl)- benzonitrile

 

127

(S or R)-N-((3-(4- fluorophenethyl)- 1-(2-(6- methylpyridin-3-yl)propan-2- yl)pyrrolidin-3- yl)methyl)-4- methyl- benzene- sulfonamide  citrate.