Patent ID: 11878173
Assignee: DUKE UNIVERSITY
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A neural stimulation device comprising:
an implantable pulse generator;
at least one electrode operatively coupled with the implantable pulse generator, wherein the implantable pulse generator transmits electrical stimulation comprising temporal patterns to neurological tissue through the at least one electrode, said temporal patterns comprising:
a first temporal pattern having a first non-regular pulse train comprising a plurality of pulses having differing inter-pulse intervals between pulses, said first temporal pattern; and
a subsequent temporal pattern having a subsequent non-regular pulse train comprising a plurality of pulses having non-regular inter-pulse intervals between the pulses to treat a neurological condition, wherein the subsequent temporal pattern: (a) is adapted from applying a model-based optimization technique, and (b) comprises a plurality of pulses having non-random, differing inter-pulse intervals between the pulses and wherein the first temporal pattern is different from the subsequent temporal pattern.