Patent ID: 11905367
Assignee: NOF CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. A method for producing the intermediate according to claim 2, wherein the following three steps:
a step (A) of coupling a monodispersed polyethylene glycol derivative represented by following formula (3) and a compound represented by following formula (4) to obtain a compound represented by following formula (5):

A-(CH2CH2O)n-CH3  (3)

wherein, in the formula (3),
A is a leaving group; and
n is an integer of 8 to 24, which represents number of repeating units of ethylene oxide units,, wherein, in the formula (4),
Y2 is a nitrogen atom; and
k is an integer of 2,, wherein, in the formula (5),
Y2 is a nitrogen atom;
n is an integer of 8 to 24, which represents number of repeating units of ethylene oxide units,
k is an integer of 2,
a step (B) of subjecting the compound represented by the formula (5) to extraction purification with water and an organic solvent, and
a step (C) of performing a treatment of cleaving the benzyl group contained in the compound represented by the formula (5) to obtain the intermediate of the branched monodispersed polyethylene glycol represented by the formula (2), are performed in the order of the step (A), the step (B) and the step (C).