Patent ID: 11969500
Assignee: FOUNDRY THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 8:
9. A depot for sustained, controlled release of a therapeutic agent, the depot comprising:
a therapeutic region including a biodegradable polymer, the therapeutic agent, and a releasing agent, the therapeutic region having a first surface, a second surface opposite the first surface, and an exposed sidewall between the first and second surfaces;
a first control region covering the first surface of the therapeutic region and having a thickness no greater than 1/50 of a thickness of the therapeutic region, the first control region comprising a biodegradable polymer; and
a second control region covering the second surface of the therapeutic region and having a thickness no greater than 1/50 of the thickness of the therapeutic region, the second control region comprising a biodegradable polymer,
wherein the therapeutic agent constitutes at least 50% of a total weight of the depot, and
wherein, when the depot is implanted at a treatment site, the depot is configured to release the therapeutic agent at the treatment site for a release duration of no less than 14 days, wherein the depot is configured to release the therapeutic agent at a first rate for an initial period of the release duration and at a second rate for a subsequent period of the release duration, the second rate being slower than the first rate.