Patent ID: 11865180
Assignee: LEIUTIS PHARMACEUTICALS LLP
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A spray formulation of Levothyroxine comprising:
(i) levothyroxine sodium in a concentration of 0.0025-5% by weight of the total formulation;
(ii) buffering agents or pH adjusting agents selected from arginine, alanine, and lysine in a concentration of 0.0015-0.5% by weight of the total formulation;
(iii) one or more solvents, wherein the solvents are selected from one or more of propylene glycol, glycerol, polyethylene glycol (PEG), and water;
(iv) sulfobutylether cyclodextrin (SBECD), and
wherein the formulation has less than 2% of total impurities when stored at 40° C., 75% RH for 3 months.