Patent ID: 11905283
Assignee: NOVARTIS AG
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 1:
2. The compound of claim 1 in which:
R1 is selected from:, R2 and R3 together with the nitrogen to which both R2 and R3 are attached form a ring selected from piperidinyl, piperazinyl, 2-oxa-8-azaspiro[4.5]decan-8-yl, 8-azaspiro[4.5]decan-8-yl and pyrrolidinyl; wherein said pyrrolidinyl, piperazinyl, 2-oxa-8-azaspiro[4.5]decan-8-yl, 8-azaspiro[4.5]decan-8-yl or piperidinyl is unsubstituted or substituted with 1 to 3 groups independently selected from amino, methyl, ethyl, amino-methyl, methyl-amino, hydroxyl, cyano, fluoro-methyl, fluoro and ((((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)amino)methyl;
R4 is selected from hydroxyl;
R5 is selected from H and methyl;
R6 is selected from hydrogen, methyl and phenyl;
R7 is selected from hydrogen, methyl, ethyl, phenyl and benzyl;
R8 is selected from hydrogen and methyl;
Y1 is selected from N and CH;
Y2 is selected from N and CH;
Y3 is selected from NH and CH2;
Y4 is selected from N and CH;
Y5 is selected from N and CH; or a pharmaceutically acceptable salt thereof.