Patent ID: 11938200
Assignee: SIDRA MEDICINE
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  G | IPC A  G

Claim 1:
2. A magnetic resonance imaging (MRI) method, comprising:
(i) obtaining a baseline chemical exchange saturation transfer (CEST) MRI image of a patient;
(ii) administering an effective amount of a non-nutritive sweetener to said patient wherein the non-nutritive sweetener comprises aspartame, neotame, acesulfame, sucralose, cyclamate, saccharin, stevioside, rebaudioside, steviol, or combinations or derivatives thereof; and
(iii) subsequent to the administration of step (ii), obtaining one or more test CEST MRI images of a tissue of the patient where the non-nutritive sweetener has accumulated wherein the step (i) and (iii) acquisition parameters are substantially the same and the one or more test CEST MRI images being derived from the presence of the non-nutritive sweetener in the tissue.