Patent ID: 11912989
Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A library that comprises:
(i) a plurality of antigen-binding domains having different amino acid sequences from one another, or
(ii) a plurality of nucleic acids that encode a plurality of antigen-binding domains having different amino acid sequences from one another, or
(iii) a plurality of antigen-binding molecules each comprising an antigen-binding domain, which have different amino acid sequences from one another, or
(iv) a plurality of nucleic acids that encode a plurality of antigen-binding molecules each comprising an antigen-binding domain, which have different amino acid sequences from one another,
wherein the plurality of antigen-binding domains or antigen-binding domains contained in the plurality of antigen-binding molecules comprises a first antigen-binding domain whose binding affinity for a first antigen varies depending on the concentration of a small molecule compound; and wherein the first antigen is not the small molecule compound.