Patent ID: 11946083
Assignee: CONAGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A biosynthetic method of making a glucoside of a capsaicinoid of interest comprising:
a) expressing an acyl-CoA synthetase (ACS) and capsaicin synthase (CS) in a transformed cellular system;
b) expressing a UDP-glucosyltransferase in the transformed cellular system, wherein the UDP-glucosyltransferase is a CaUGT2 from C. roseus and either is encoded by a DNA sequence at least 75% identical to SEQ ID NO: 5 and/or comprises an amino acid sequence at least 90% identical to SEQ ID NO: 6;
c) growing the cellular system in a medium; and,
d) producing the glucoside of a capsaicinoid of interest.