Patent ID: 11912707
Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 9:
10. A method of activating a mu-opioid receptor comprising contacting the mu-opioid receptor with the compound of claim 1 so as to thereby activate the mu-opioid receptor, or
of antagonizing a delta-opioid receptor and/or a kappa-opioid receptor comprising contacting the delta-opioid receptor and/or the kappa-opioid receptor with the compound of claim 1 so as to thereby antagonize the delta-opioid receptor and/or the kappa-opioid receptor, or
of treating a subject afflicted with pain, a depressive disorder, a mood disorder or an anxiety disorder comprising administering an effective amount of the compound of claim 1 to the subject so as to thereby treat the subject afflicted with pain, the depressive disorder, the mood disorder or the anxiety disorder, or
of treating a subject afflicted with pain comprising administering to the subject an effective amount of an NMDA receptor antagonist, an NMDA receptor partial agonist, a neurokinin 1 receptor antagonist, or a delta-opioid receptor agonist and an effective amount of the compound of claim 1 so as to thereby treat the subject afflicted with pain, or
of treating a subject afflicted with a depressive disorder, a mood disorder or an anxiety disorder comprising administering to the subject an effective amount of an NMDA receptor antagonist, an NMDA receptor partial agonist, a neurokinin 1 receptor antagonist, a neurokinin 2 receptor antagonist, a neurokinin 3 receptor antagonist or a delta-opioid receptor agonist and an effective amount of the compound of claim 1 so as to thereby treat the subject afflicted with the depressive disorder, the mood disorder or the anxiety disorder.