Patent ID: 11872207
Assignee: MCMASTER UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of treating breast cancer, comprising administering an effective amount of one or more compounds of Formula (Ia), or a pharmaceutically acceptable salt and/or solvate thereof, to a subject in need thereof, wherein the compounds of the Formula (Ia) are:, , wherein, R1 is selected from C1-6alkyl, haloC1-6alkyl, OC1-6alkylene, OC1-6alkylene-OC1-6alkyl, OC1-6alkylenearyl, OH and unsubstituted or substituted aryl;, the substituents on R1 are selected from OC1-6alkylene-NR6R7 and OC1-6alkylene-N(O)R6R7;, R2 is selected from C1-6alkyl, aryl and C1-6alkylene-OC1-6alkyl ;, R3 is selected from H, C1-6alkyl and SO2R8;, R4 is selected from C1-6alkyl, haloC1-6alkyl and unsubstituted or substituted aryl;, the substituents on R4 are selected from one or more of halo, C1-6alkyl, OC1-6alkylene, NR9C(O)C1-6alkyl and COOH;
R6, R7, R8 and R9 are independently selected from one or more of H and C1-6 alkyl; and
one or more available hydrogens are optionally replaced with D and/or F;
or a pharmaceutically acceptable salt and/or solvate thereof,, provided the compound is not, , or a pharmaceutically, acceptable salt and/or solvate thereof.