Patent ID: 11963721
Assignee: CENTRE FOR EYE RESEARCH AUSTRALIA LIMITED
Field: Measurement (Instruments)
Classification: CPC A  G | IPC A  G

Claim 17:
18. A system for quantifying a biomarker of a tissue using light reflectance data, the system comprising:
an optical assembly comprising one or more light sources arranged to illuminate a portion of the tissue at wavelengths with light within at least two selected spectral sub-intervals;
an imaging assembly comprising an imaging sensor arranged to receive light reflected from the portion of the tissue and translate the light to digital data; and
a processing module arranged to receive data from the imaging sensor and being configured to:
retrieve, from a memory, a spectral signature of at least one spectral confounder present in the tissue causing a spectral variability in the light reflectance data;
combine and process the data received from the imaging sensor and the spectral signature of the at least one spectral confounder to extract spectral information and form a multispectral or hyperspectral representation of the tissue;
extract spectral features related to the at least one spectral confounder from the light reflectance data; and
process the multispectral or hyperspectral representation of the tissue to quantify the biomarker;

wherein the at least two selected spectral sub-intervals are specific to a known variable of interest and wherein at least one spectral confounder causing a spectral variability of the received data is present in the tissue.