Patent ID: 11959076
Assignee: 10X GENOMICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. The method of claim 1, wherein analyzing the second analyte in the second biological sample mounted on the third substrate comprises:
separating the first substrate from the second substrate;
contacting the second biological sample with a plurality of analyte capture agents, wherein an analyte capture agent of the plurality of analyte capture agents comprises
(i) an analyte binding moiety;
(ii) a second sample index sequence that identifies the second biological sample, and
(iii) a capture agent barcode domain,
wherein the analyte binding moiety specifically binds to the second analyte, and wherein the capture agent barcode domain comprises an analyte binding moiety barcode and an analyte capture sequence;

when the at least a portion of the second biological sample is aligned with at least a portion of the array, releasing the capture agent barcode domain from the analyte capture agent; and
coupling the capture agent barcode domain to a second capture domain of a second capture probe, wherein the second capture probe comprises a second spatial barcode.