Patent ID: 11911099
Assignee: DUKE UNIVERSITY
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 9:
10. A method comprising:
generating a first topological map of a treatment site based on a first surface scan of the treatment site;
controlling a laser signal to create a first feature in the treatment site after the generation of the first topological map;
generating a second topological map of the treatment site, the second topological map being based on a second surface scan of the treatment site performed after creation of the first feature;
developing a model of the reaction of a first tissue in the treatment site to the laser signal based on a first difference between the first and second topological maps;
estimating a first tissue parameter for the first tissue based on the model, wherein the first tissue parameter is selected from the group consisting of threshold radiant exposure, tissue density, ablation enthalpy, absorption coefficient, optical scattering coefficient, reduced scattering coefficient, refractive index, scattering anisotropy coefficient, and color; and
establishing at least one laser-signal parameter of the laser signal for a first treatment path through the treatment site based on the estimated first tissue parameter, wherein the at least one laser-signal parameter is selected from the group consisting of peak power, focal length, beam diameter, and incident radiant exposure.