Patent ID: 11878088
Assignee: THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  D | IPC A  C  D

Claim 3:
4. A method of producing an electrospun chitosan nanofiber comprising N-tert-butoxycarbonyl (t-Boc), the method comprising:
(a) electrospinning a trifluoroacetic acid solution comprising chitosan to produce a chitosan nanofiber comprising immobilized salt residues;
(b) removing one or more immobilized salt residues from the chitosan nanofiber with an organic solvent comprising triethylamine and, optionally, acetone, thereby generating one or more free amino groups on the chitosan nanofibers; and
(c) contacting the free amino groups with di-tert-butyl dicarbonate, thereby producing a chitosan nanofiber comprising N-tert-butoxycarbonyl (t-Boc).