Patent ID: 11905232
Assignee: NOGRA PHARMA LIMITED
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A process for preparing a substantially optically pure compound of Formula (VII):, the process comprising:
reacting a compound of Formula (I):, with an activating agent, in the optional presence of a base, to form an intermediate of Formula (I-A):, wherein LG is a leaving group;
treating the intermediate of Formula (I-A) with a base solution in the presence of an alcohol solvent, to eliminate the leaving group and thereby forming an intermediate of Formula (I-B):, hydrolyzing the intermediate of Formula (I-B) to form a compound of Formula (IV):, hydrogenating the compound of Formula (IV) to form a compound of Formula (V):, resolving the compound of Formula (V) to form a substantially optically pure compound of Formula (VI):, and
acylating the compound of Formula (VI) to form the compound of Formula (VII).