Patent ID: 11918683
Assignee: ALLERO THERAPEUTICS B.V.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  Y | IPC A

Claim 0:
1. A method for inducing immune tolerance in a subject, the method comprising administering to the oral mucosa of the subject a mucoadhesive carrier wherein the mucoadhesive carrier is a mucoadhesive patch comprising mucoadhesive nanofibers incorporating or loaded with a non-living bacterial particle and an antigen-containing extract or wherein the mucoadhesive carrier is a hydrogel or film of water swellable, cross-linked mucoadhesive polymers that are impregnated or loaded with the bacterial particle and the extract, and wherein the non-living bacterial particle is derived from a probiotic bacterium selected from:
a) a heat-treated Gram-positive bacterium;
b) a chemically sterilized bacterium.