Patent ID: 11940449
Assignee: ID-FISH TECHNOLOGY, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC G  A  C | IPC A  C  G

Claim 10:
11. A method for detecting IgG-class antibodies resulting from infection by a coronavirus, if present in a biological sample obtained from a subject suspected of having a coronavirus infection, the method comprising:
a) providing a composition comprising at least four labelled and/or tagged and/or bound amino acid sequences, wherein the at least four labelled and/or tagged and/or bound amino acid sequences comprise amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4, and variants thereof which retain the immunological binding profile of the corresponding non-variant;
b) providing the biological sample obtained from the subject suspected of having a coronavirus infection;
c) contacting the biological sample with the composition of step a) under conditions appropriate for specific antibody binding to an epitope; and
d) detecting specific binding of IgG-class antibodies with the amino acid sequences of step a), wherein the sample is scored as positive for coronavirus infection when positive binding is detected for: SEQ ID NO: 1 or SEQ ID NO: 3 and SEQ ID NO: 4; SEQ ID NO: 1 or SEQ ID NO: 3 and SEQ ID NO: 2; or SEQ ID NO: 2 and SEQ ID NO: 4.