Patent ID: 11932690
Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 25:
26. The method of claim 25, wherein
(a) the hinge/spacer region comprises a CD28 polypeptide and the transmembrane domain comprises a CD28 polypeptide;
(b) the hinge/spacer region comprises a CD84 polypeptide and the transmembrane domain comprises a CD84 polypeptide;
(c) the hinge/spacer region comprises a CD166 polypeptide and the transmembrane domain comprises a CD166 polypeptide;
(d) the hinge/spacer region comprises a CD8a polypeptide and the transmembrane domain comprises a CD8a polypeptide;
(e) the hinge/spacer region comprises a CD8b polypeptide and the transmembrane domain comprises a CD8b polypeptide; or
(f) the hinge/spacer region comprises a CD28 polypeptide and the transmembrane domain comprises an ICOS polypeptide.