Patent ID: 11945853
Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. An expression vector comprising a polynucleic acid for expressing ACE2 in a bacterium, the polynucleic acid comprising:
a promoter,
a nucleic acid encoding a secretion signal peptide,
a nucleic acid encoding a carrier protein, wherein the nucleic acid encoding the carrier protein has:
(i) a polynucleic acid sequence having at least 80% sequence identity to SEQ ID NO: 3 or
(ii) a polynucleic acid sequence having at least 95% sequence identity to SEQ ID NO: 18,

a nucleic acid encoding ACE2, and;
wherein the nucleic acids encoding the secretion signal peptide, carrier protein and ACE2 encode a fusion protein and are operably linked to the promoter.