Patent ID: 11905293
Assignee: TOPADUR PHARMA AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of formula I, , or pharmaceutically acceptable salt, solvate or hydrate thereof, wherein
R1 is C1-C3alkyl optionally substituted with F;
R2 is H, C1-C3alkyl optionally substituted with OH; CHO, CN, or CR8═N—OR9;
R3 is C1-C4alkyl optionally substituted with F, C1-C3alkoxy, or C3-C6cycloalkyl;
R4 is C1-C6alkyl optionally substituted with C1-C6alkoxy;
R5 is SO2NR13NR14;
R8 is H, CH3 or C2H5;
R9 is H or C1-C3 alkyl optionally substituted with OH;
R13 and R14, together with the nitrogen atom to which they are attached, form a heterocyclic ring, wherein said heterocyclic ring is substituted with at least one R15; and
R15 is C1-C6alkyl substituted with at least one ONO or ONO2, and is optionally substituted with OH.