Patent ID: 11932845
Assignee: GENOMATICA, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 4:
5. The microbial organism of claim 1, further comprising a genetic modification selected from:
(i) a genetic modification that increases expression of pyruvate dehydrogenase relative to the microbial organism in the absence of the genetic modification;
(ii) a genetic modification that decreases expression of an aerobic respiratory control regulatory system relative to the microbial organism in the absence of the genetic modification;
(iii) a genetic modification that increases expression of an NADH insensitive citrate synthase relative to the microbial organism in the absence of the genetic modification;
(iv) a genetic modification that decreases expression of malate dehydrogenase relative to the microbial organism in the absence of the genetic modification;
(v) a genetic modification that decreases expression of lactate dehydrogenase relative to the microbial organism in the absence of the genetic modification;
(vi) a genetic modification that decreases expression of pyruvate formate lyase relative to the microbial organism in the absence of the genetic modification; and
(vii) a combination of two or more, three or more, four or more, five or all of the genetic modifications of parts (i)-(vi).