Patent ID: 11857512
Assignee: GENZYME CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 5:
6. The process according to claim 1, wherein the process comprises the following steps:
(a) sieving each of a first portion of mannitol, silica, venglustat malate, flavor, and sodium stearyl fumarate, and optionally sucralose;
(b) combining the venglustat malate with the sieved mannitol, silica, flavor, and sodium stearyl fumarate, and optionally sucralose, optionally wherein each ingredient is sieved sequentially into a common container to combine the ingredients;
(c) blending and/or milling and/or granulating the resulting mixture;
(e) sieving a second portion of mannitol, low-substituted hydroxypropyl cellulose, and crospovidone, and adding these sieved ingredients to the mixture from step (c);
(f) blending and/or milling and/or granulating the resulting mixture;
(h) sieving magnesium stearate and adding it to the mixture from step (f);
(i-j) blending and/or milling and/or granulating the resulting mixture;
(l) compressing the resulting material to form a tablet; and
(n) optionally packaging the resulting finished dosage form.