Patent ID: 11866471
Assignee: TORO MIYAZAKI
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 3:
4. A mutant mouse apoptosis inhibitor of macrophage (AIM) comprising an amino acid sequence of any one of the following (a) to (c) and having an activity of wild-type mouse AIM:
(a) an amino acid sequence wherein cysteine at amino acid number 168 of the amino acid sequence shown in SEQ ID NO: 2 is substituted with another amino acid,
(b) an amino acid sequence having a percent identity of not less than 98% with the amino acid sequence of (a), wherein the amino acid sequence retains the cysteines present in the amino acid sequence of (a) and the substituted another amino acid at amino acid number 168, or
(c) an amino acid sequence further comprising deletion, addition, insertion or substitution of one to five amino acids or a combination thereof at a position other than cysteines present in the amino acid sequence of (a) and the substituted another amino acid of (a).