Patent ID: 11942313
Assignee: SHIMADZU CORPORATION
Field: Measurement (Instruments)
Classification: CPC H  G | IPC G  H

Claim 7:
8. A mass spectrometer comprising:
an ion source using an atmospheric pressure ionization method for ionizing a component contained in a liquid sample;
a mass separator configured to separate ions derived from the component contained in the liquid sample in accordance with a mass-to-charge ratio;
a detector configured to detect the separated ions;
to optimize N parameters that affect ionization efficiency in the ion source, N being an integer of 2 or more,
a measurement controller configured to cause the ion source, the mass separator, and the detector to repeatedly execute measurement on a sample containing a target component while changing a value of each of the N parameters or a value set of M parameters among the N parameters in a plurality of stages, M being an integer smaller than N; and
a parameter determiner configured to sequentially find an optimum value of each of the N parameters or an optimum value set of the M parameters based on a result of the measurement executed under control of the measurement controller, wherein
the measurement controller causes measurement to be repeatedly executed while changing a value of at least one parameter whose physical quantity is temperature among the N parameters or a value set of the M parameters including the at least one parameter prior to all parameters whose physical quantities are other than temperature among the N parameters, and
the parameter determiner optimizes the at least one parameter whose physical quantity is temperature prior to all the parameters whose physical quantities are other than temperature.