Patent ID: 11877866
Assignee: EFFERENT LABS, INC.
Field: Measurement (Instruments)
Classification: CPC A  G | IPC A  G

Claim 17:
18. A method for acquiring a physiological measurement from within a host organism, the method comprising:
a) maintaining fluid communication between the host organism and live cells that are sustained within a sample chamber that is implanted within the host organism, wherein the live cells are treated to fluoresce in response to an excitation light energy having an excitation wavelength and an illumination intensity;
b) within the host organism, directing the excitation light energy along a light path comprising a reflective surface that directs light out of a primary plane such that the light path defines a folded optical axis that extends into the sample chamber;
c) collecting a fluoresced light energy emerging from the sample chamber;
d) separating the fluoresced light energy from a residual excitation light energy along the light path, with a beam splitter, and sensing the fluoresced light at a detector that is configured to generate a detector output signal according to the detected fluoresced light energy;
e) amplifying and digitizing the detector output signal to generate digital data;
f) transmitting the digital data from within the host organism to a receiver that is external to the host organism;
g) storing the transmitted digital data in a memory that is in signal communication with the receiver and is external to the host organism; and
h) at a time interval(s), repeating steps (a)-(g), while varying the illumination intensity and/or excitation wavelength of the excitation light energy to reduce noise levels in the detector output signal.