Patent ID: 11970486
Assignee: JANSSEN PHARMACEUTICA NV
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A compound having the structure:

R1(L1)nL2-B-Het-R5 

wherein B has the structure:, Het is, n is 0 or 1;
o is 0, 1, or 2;
p and r are, independently, 0 or 1;
X1 is N or CR6;
X2 is N;
L1 is —O—;
L2 is CR2R3;
R1 is optionally substituted phenyl, optionally substituted C3-C7 cycloalkyl, optionally substituted C3-C7 cycloalkyl C1-C6 alkyl, or C2-C9 heterocycle optionally substituted with C1-C6 alkyl or C1-C6 heteroalkyl;
R2 and R3 are each, independently, hydrogen or R2 and R3 combine with the carbon to which they are attached to form a carbonyl;
each R4 is, independently, halogen, hydroxyl, optionally substituted C1-C6 alkyl, or two R4 combine with the carbon to which they are attached to form a carbonyl;
R5 is a bicyclic heteroaryl comprising a 6-membered ring, wherein R5 is unsubstituted or is substituted with 1 to 4 substituents selected from the group consisting of C1-C6 alkyl and C2-C9 heterocyclyl; and
each R6 is, independently, hydrogen, halogen, or optionally substituted C1-C6 alkyl,
or a pharmaceutically acceptable salt thereof.