Patent ID: 11884676
Assignee: VANDERBILT UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of formula (Ib):, or a pharmaceutically acceptable salt or stereoisomer thereof,
wherein:
R1 is H, C1-C4 alkyl, C1-C4 haloalkyl, C1-C3 alkylene-ORa, C1-C3 alkylene-C3-C6 cycloalkyl, or C3-C6 cycloalkyl;
Ra is C1-C4 alkyl, C1-C4 haloalkyl, or C3-C6 cycloalkyl;
R2 is H, C1-C4 alkyl, C1-C3 alkylene-ORb, NHRb, NRbRb, ORb, or C3-C6 cycloalkyl;
R7 is H, halo, C1-C4 alkyl, NRbRb, or C3-C6 cycloalkyl;
each R3 is independently C1-C4 alkyl, C1-C4 haloalkyl, or C3-C6 cycloalkyl; or
two Rb, taken together with the nitrogen heteroatom to which they are attached, form a monocyclic 4- to 7-membered heterocyclyl;
R3 is H, C1-C4 alkyl, C1-C3 alkylene-ORc, or C3-C6 cycloalkyl;
Rc is C1-C4 alkyl, C1-C4 haloalkyl, or C3-C6 cycloalkyl;
R4 is halo or C1-C4 alkyl;
X is CR5a;
R5a is H, halo, or C1-C4 alkyl;
R5b is halo, CN, C1-C2 alkyl, C1-C2 fluoroalkyl, OC1-C2 alkyl, OC1-C2 fluoroalkyl, or C3-C6 cycloalkyl;
n is 0; and
o is 0 or 1.