Patent ID: 11911631
Assignee: DREXEL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 16:
17. A multimodality simultaneous thermobrachytherapy treatment system comprising:
a biocompatible expandable balloon adapted and configured to be inflated within a resection cavity of a patient;
magnetic material lying within the biocompatible expandable balloon; and
a biocompatible sheath;
a first fixation collar and a second fixation collar external to the biocompatible sheath, where the first fixation collar is adapted and configured to seal a first end of the biocompatible expandable balloon to a first portion of the biocompatible sheath, and where the second fixation collar is adapted and configured to seal a second end of the biocompatible expandable balloon to a second portion of the biocompatible sheath;
one or more catheters positioned within the biocompatible sheath, the one or more catheters adapted and configured to extend from outside of the patient to an interior of the biocompatible balloon, at least one of the one or more catheters coupled to a remote afterloader;
a radiation source removably within the biocompatible expandable balloon;
a suture collar external to the sheath, the suture collar comprising suture holes adapted and configured for fixation to a tissue surface external to the patient; and
a non-contacting induction coil adapted and configured to apply a magnetic field surrounding the balloon, the magnetic field adapted and configured to be:
generated external to the patient;
inductively coupled to and thereby heat the magnetic material lying within the biocompatible expandable balloon to produce a substantially non-ablative temperature distribution of about 40-45° C. for about 30-60 mins in the tissue surrounding a resection cavity wall simultaneously with delivery of radiation from the radiation source; and
in a frequency range of about 50 kHz to about 500 kHz.