Patent ID: 11905229
Assignee: FUDAN UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  B  Y | IPC B  C

Claim 5:
6. The method of claim 1, wherein in step (S4), the catalyst is pyridine, N,N-dimethylaniline, triethylamine or N,N-dimethylformamide;
a molar ratio of N-(2,6-dichlorophenyl)-2-hydroxy-N-phenylacetamide (IV) to thionyl chloride to the catalyst is 1:(1-4):(0.001-0.5);
the chlorination is performed in an organic solvent selected from the group consisting of N,N-dimethylformamide, dimethyl sulfoxide, thionyl chloride, toluene, acetonitrile, dichloromethane, 1,2-dichloroethane, ethyl acetate and acetone; and
the chlorination is performed at 10-100° C. for 0.5-10 h.