Patent ID: 11957651
Assignee: PROFESSIONAL DIETETICS S.P.A.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of treatment for a mitochondrial dysfunction-related neurodegenerative disease, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising an active agent, said active agent comprising leucine, isoleucine, valine, threonine, lysine, citric acid, succinic acid and malic acid,
wherein the citric acid:malic acid:succinic acid weight ratio is between 10:1:1 and 1.3:1:1,
wherein the composition comprises the amino acids isoleucine, leucine and valine in an amount by weight between 35% and 65%,
wherein the weight ratio between (i) the sum of citric acid, malic acid and succinic acid and (ii) the sum of leucine, isoleucine and valine is between 0.1 and 0.4,
wherein the weight ratio between (i) the sum of citric acid, malic acid and succinic acid and (ii) the sum of leucine, isoleucine, valine, lysine and threonine is between 0.05 and 0.3, and
wherein the weight ratio between leucine and citric acid is comprised between 5 and 1, wherein the mitochondrial dysfunction-related neurodegenerative disease is selected in the group consisting of Alzheimer's disease, Parkinson's disease, and Huntington's disease.