Patent ID: 11863041
Assignee: UNIVERSITY OF MASSACHUSETTS
Field: Measurement (Instruments)
Classification: CPC H  G | IPC G  H

Claim 0:
1. A method for tissue delipidation, comprising:
providing a whole adult mouse brain submerged in an electrically conducting solution comprising NaOH, LiOH and H3BO3, or a salt thereof, in a cylindrically shaped channel having a longitudinal dimension, wherein the whole adult mouse brain is positioned stationary to the cylindrically shaped channel; and
applying an electric field within the cylindrically shaped channel and simultaneously applying a magnetic field within the cylindrically shaped channel and perpendicular to the electric field, thereby inducing lipid particles in the whole adult mouse brain to flow in a direction perpendicular to both the electric field and the magnetic field, wherein delipidation is completed in about 15 hours,
wherein
the electrically conducting solution comprises a polar solvent and an electrolyte; and
the electric field and the magnetic field are both perpendicular to the longitudinal dimension and jointly induce charged lipid particles in the whole adult mouse brain to flow in a direction perpendicular to both the electric field and the magnetic field.