Patent ID: 11921115
Assignee: OPKO DIAGNOSTICS, LLC
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 30:
31. The method of claim 1, the method further comprising performing a second immunoassay to measure a level of a second prostate antigen in the sample, wherein the second prostate antigen is human kallikrein 2 (hK2);
performing the second immunoassay to measure the level of the second prostate antigen in each titer in a second set of prostate antigen standards, wherein the second set of prostate antigen standards comprises between 3 and 15 titers containing known levels of the second prostate antigen, wherein each intermediate titer of the second set of prostate antigen standards is equidistant from the titer above and below it on a logarithmic scale, wherein the quantity of the smallest non-zero titer of the second set is below the limit of quantification of the second immunoassay, and wherein the level of the second prostate antigen in the largest titer in the second set is between i) a blood level of the second prostate antigen in the upper quartile of the target population of male subjects and ii) a level of the second prostate antigen that is 75-fold higher than the blood level in the upper quartile of the target population of male subjects; and
determining the level of the second prostate antigen in the sample based on the measured levels of the second prostate antigen in the second set of prostate antigen standards.