Patent ID: 11866790
Assignee: BEIJING ORIGINPOLY BIO-TEC CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 5:
6. The detection kit according to claim 5, wherein the detection kit further comprises target gene detection probes for correspondingly detecting the methylated statuses of the methylated fragments, wherein the nucleotide sequence of the target gene detection probe is shown below:
for PCDHB18P gene:
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 1 is SEQ ID NO: 15,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 2 is SEQ ID NO: 18,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 3 is SEQ ID NO: 21;
for CDO1 gene:
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 4 is SEQ ID NO: 24,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 5 is SEQ ID NO: 27,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 6 is SEQ ID NO: 30;
for HOXA9 gene:
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 7 is SEQ ID NO: 33,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 8 is SEQ ID NO: 36,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 9 is SEQ ID NO: 39;
and for LYPD5 gene:
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 10 is SEQ ID NO: 42,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 11 is SEQ ID NO: 45,
the nucleotide sequence of a detection probe for the methylated fragment of SEQ ID NO: 12 SEQ ID NO: 48.