Patent ID: 11972859
Assignee: VENTANA MEDICAL SYSTEMS, INC.
Field: Medical technology (Instruments)
Classification: CPC G | IPC G

Claim 7:
8. A system comprising:
a processing system; and
a computer-readable medium storing instructions which, when executed by the processing system, cause the system to perform a method comprising:
calculating one or more first image feature metrics from a plurality of images of biological samples derived from a first patient population;
generating tissue feature data for the first patient population by combining the one or more first image feature metrics with tissue analysis data corresponding to the biological samples derived from the first patient population;
calculating a first patient population correlation matrix based on the tissue feature data for the first patient population and clinical attributes of the first patient population;
calculating one or more second image feature metrics from a plurality of images of biological samples derived from a second patient population;
generating tissue feature data for the second patient population by combining the one or more second image feature metrics with tissue analysis data corresponding to the biological samples derived from the second patient population;
calculating a second patient population correlation matrix based on the tissue feature data for the second patient population and clinical attributes of the second patient population; and
determining, based on a comparison of the first patient population correlation matrix and second patient population correlation matrix, that the tissue feature data for the first patient population is similar to the tissue feature data for the second patient population; and
in response to determining that the tissue feature data for the first patient population is similar to the tissue feature data for the second patient population, determining an extent to which a first clinical trial data set associated with the first patient population is represented by a second clinical trial data set associated with the second patient population.