Patent ID: 11884939
Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 15:
16. The recombinant VACV or MVA nucleic acid sequence of claim 15, wherein the open reading frame of the heterologous nucleic acid sequence is operably linked to a promoter that is capable of directing expression of the selectable marker; or
wherein the selectable marker is a bioluminescent protein, a fluorescent protein, a chemiluminescent protein, a xanthine-guanine phosphoribosyl transferase gene (gpt), or any combination thereof; or
wherein the selectable marker is green fluorescent protein (GFP); or
wherein the heterologous nucleic acid sequence further comprises an open reading frame that encodes human Fms-like tyrosine kinase 3 ligand (hFlt3L).