Patent ID: 11939394
Assignee: MERUS N.V.
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 15:
16. The bispecific antibody of claim 1, wherein the VH chain of the variable domain that binds EGFR comprises the amino acid sequence of SEQ ID NO: 36 having at most 15 amino acid insertions, deletions, substitutions or a combination thereof which are not in the CDR1, CDR2 or CDR3 region, and the VH chain of the variable domain that binds LGR5 comprises the amino acid sequence of SEQ ID NO: 26 having at most 15 amino acid insertions, deletions, substitutions or a combination thereof which are not in the CDR1, CDR2 or CDR3 region.