Patent ID: 11912976
Assignee: CEIDOS SA
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A cell culture monitoring system comprising:
a monitoring apparatus configured for coupling to a cell culture tank containing a cell culture medium comprising cells therein; and
a fluid circulation system configured for fluidic coupling to the cell culture tank, the fluid circulation system comprising:
supply and return conduits, and
a dielectrophoresis cartridge configured for connection to the cell culture tank via said supply and return conduits, the dielectrophoresis cartridge comprising:
a base and
an electrode support having electrodes in or on the electrode support, the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone arranged above a measuring chamber formed between the electrode support and a floor of the base forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber,

wherein the monitoring apparatus comprises:
a computing unit,
an image capture system connected to the computing unit, and
a cartridge holder portion for receiving said dielectrophoresis cartridge such that the image capture system may detect cells flowing through said measuring chamber.