Patent ID: 11873489
Assignee: SILENCE THERAPEUTICS GMBH
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 4:
5. The nucleic acid of claim 1, wherein the nucleotides of the first strand are modified by a first modification on the odd numbered nucleotides, and modified with a second modification on the even numbered nucleotides, and wherein the nucleotides of the second strand are modified on the odd numbered nucleotides with the second modification and modified with the first modification on the even numbered nucleotides, wherein the first strand is numbered 5′ to 3′, the 5′-most nucleotide being nucleotide number 1 of the first strand and the second strand is numbered 3′ to 5′, the 3′-most nucleotide being nucleotide number 1 of the second strand.