Patent ID: 11873323
Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A nucleic acid molecule comprising a nucleotide sequence which encodes a peptide capable of spontaneously forming an isopeptide bond with a polypeptide comprising an amino acid sequence as set forth in SEQ ID NO: 2, said peptide comprising an amino acid sequence as set forth in SEQ ID NO: 1, wherein:
(i) X at position 1 is arginine or no amino acid;
(ii) X at position 2 is glycine or no amino acid;
(iii) X at position 5 is histidine or threonine;
(iv) X at position 11 is alanine, glycine or valine; and
(v) X at position 14 is arginine or lysine,, wherein when X at position 1 is no amino acid, X at position 2 is no amino acid;
and wherein said isopeptide bond forms between the aspartic acid residue at position 10 of SEQ ID NO: 1 and the lysine residue at position 34 of SEQ ID NO: 2.