Patent ID: 11872319
Assignee: PRIVO TECHNOLOGIES, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A device for rapid delivery of a therapeutic agent to a surgical cavity, the device comprising:
a polymeric matrix having first and second opposed surfaces,
wherein the matrix comprises chitosan, a particle adhesion inhibitor comprising hydroxyproplymethylcellulose (HPMC), a plurality of particles having an average diameter between 500 nm and 2000 nm, and one or more additives selected from the group consisting of a hydration promotor, a particle aggregation inhibitor, and combinations thereof,
wherein the particles are embedded within the matrix so as to be directly surrounded by, and in contact with, the matrix,
wherein the particles comprise the therapeutic agent and chitosan,
wherein:
the first surface of the matrix is configured to be applied to the surgical cavity;
the device is configured to provide release of the particles through the first surface;
the device is sterilized;
the device provides release of approximately 20% to 100% of the therapeutic agent within 20 minutes of application to the surgical cavity; and
when present, the particle adhesion inhibitor, the hydration promotor, and the particle aggregation inhibitor are compounds mutually distinct from one another.