Patent ID: 11931951
Assignee: NEW JERSEY INSTITUTE OF TECHNOLOGY
Field: Other special machines (Mechanical engineering)
Classification: CPC B  A | IPC A  B

Claim 10:
11. A method for making a 3D scaffold, comprises:
directly and sequentially printing a photocurable matrix material and a photocurable sacrificial material in a single step by a dual extrusion based printing;
fabricating a vascularized scaffold;
forming an embedded channels having a diameter either same or varied within a range of about 100 μm-500 μm and
wherein the photocurable matrix material and the sacrificial material is not a shear thinning material, and the sequential printing of the sacrificial material is within an interface of the matrix material;
(vi) dual printing a matrix material up to a specific thickness for forming a printed layer for the printing of the photocurable polymer matrix material layer;
(vii) exposing the matrix material layer to a light source after each of the printed layer, and partially crosslinking the printed layer to allow self-supporting of the matrix material;
(viii) printing the sacrificial layer with a sacrificial material for the printing of the sacrificial polymer material layer;
(ix) exposing the sacrificial layer to the light source after printing of the sacrificial material;
(x) printing anew layer of matrix material;
repeating the above (i) through (v) steps to create a vascular scaffold in a desired thickness;
exposing the scaffold to the light source to fully crosslink the scaffold after printing and the desired thickness or the human scale is achieved;
immersing the scaffold into an aqueous solution to remove the sacrificial material for a formation of channels.