Patent ID: 11946103
Assignee: SINGULAR GENOMICS SYSTEMS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A compound having the formula:, wherein
B is a divalent nucleobase;
R1 is a polyphosphate moiety, 5′-nucleoside protecting group, monophosphate moiety, or nucleic acid moiety;
R2 is hydrogen or —OH;
R3 is a reversible terminator moiety, hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
R4 is a detectable moiety;
L100 is a divalent linker comprising, wherein
R5 and R6 are independently unsubstituted alkyl, —CN, —OH, —NH2, —COOH, —CONH2, —NO2, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, substituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and
W1 and W2 are —O—.