Patent ID: 11939580
Assignee: RZNOMICS INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 22:
23. A method of producing a circular RNA in a cell population or making a cell population comprising the circular RNA, said method comprising contacting cells of the cell population with a composition comprising:
a) (1) the self-circularization RNA construct of claims 1 and (2) a delivery vehicle for delivering the circular RNA to the cells, said delivery vehicle comprising a nanocarrier selected from the group consisting of a lipid, a polymer and a lipo-polymeric hybrid,
b) (1) a vector comprising the self-circularization RNA construct of claims 1, and (2) a delivery vehicle for delivering the circular RNA to the cells, said delivery vehicle comprising a nanocarrier selected from the group consisting of a lipid, a polymer and a lipo-polymeric hybrid; or
c) (1) the circular RNA produced by the vector of b)(1), and (2) a delivery vehicle for delivering the circular RNA to the cells, said delivery vehicle comprising a nanocarrier selected from the group consisting of a lipid, a polymer and a lipo-polymeric hybrid.