Patent ID: 11897900
Assignee: JANSSEN PHARMACEUTICA NV
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 12:
13. The compound as claimed in claim 1, wherein the compound is selected from the group consisting of
3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
3-(7-Cyclopropoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(7-Cyclopropoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(7-Cyclopropoxy-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-((1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′1)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3 yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-34(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(711)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(1-(cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(711)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(1-(cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(71-1)-yl)methyl)phenyl)propanoic acid;
3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
(R)-3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid
(*S)-3-(3-((1,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-((3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(34(*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-((3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3 [1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(5-((l′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethylpropanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(541′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethylpropanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(5-((l′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethylpropanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((7′-(2-morpholinoethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S) 2,2-Dimethyl-3-(4-methyl-3-((7′-(2-morpholinoethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((7′-(2-morpholinoethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(3-((7′-(3-Hydroxypropoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl-2,2′-dimethyl-3-(8-methyl-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S) 3-(3-((7′-(3-Hydroxypropoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl-2,2′-dimethyl-3-(8-methy-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R) 3-(3-((7′-(3-Hydroxypropoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl-2,2′-dimethyl-3-(8-methyl-3-trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(R/S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(R/S)-3-(4-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(4-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(5-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
(*S)-3-(5-41′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
(*R)-3-(5-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-6-methylpyridin-3-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid;
(R/S)-3-(1-Ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-5-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*S)-3-(1-Ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-5-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-3-(1-Ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-5-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-(difluoromethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(341′,1′-dioxidospiro[oxetane-3,3′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-41′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin-2′(3′H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-41′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin-2′(3′H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(4-(Difluoromethyl-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(4-(Difluoromethyl-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R) 3-(4-(Difluoromethyl-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(R-5,5-dioxido-7a,8,9,10-tetrahydropyridi[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(341′,1′-dioxidospiro[benzo[b][1,4,5]oxathiazepin-4,3′-oxetan]-2,(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(5′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(341′,1′-dioxidospiro[benzo[b][1,4,5]oxathiazepin-4,3′-oxetan]-2,(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-41′,1′-dioxidospiro[benzo[b][1,4,5]oxathiazepin-4,3′-oxetan]-2,(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(5-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-((5′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((*R)-7a-methyl-5,5-dioxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*R)-3(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((*R)-7a-methyl-5,5-dioxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*S)-3(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((*R)-7a-methyl-5,5-dioxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
3-(4-Chloro-3-(((*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Chloro-3-(((*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2, ,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Chloro-3-(((*S)-5,5-dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
3-(4-Chloro-3-((1′,1′-dioxoidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Chloro-3-((1′,1′-dioxoidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′ II)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Chloro-3-((1′,1′-dioxoidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′11)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(4-Chloro-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Chloro-34(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Chloro-3-(((*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
3-(4-Chloro-3-(((*S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Chloro-3-(((*S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Chloro-3-(((*S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
3-(4-Chloro-3-((1′,1′-dioxoidospiro[benzo[b]]oxethiazepine-4,3′-oxetan]-2(31/)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Chloro-3-((1′,1′-dioxoidospiro[benzo[b]]oxethiazepine-4,3′-oxetan]-2(31/)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Chloro-3-((1′,1′-dioxoidospiro[benzo[b]]oxethiazepine-4,3′-oxetan]-2(31/)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((8-Fluoro-1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepin]-4,1′-cyclopropan]-2(31/)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((8-Fluoro-1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl]-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((7′-Chloro-1′,1′-dioxidospiro(cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′11)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((7′-((2-Hydroxyethyl)amino-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridinn-7-yl)propanoic acid;
(*S)-3-(3-((7′-((2-Hydroxypropyl)amino-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridinn-7-yl)propanoic acid;
(*S)-3-(3-((7′-Hydroxy-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3,-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(4-Cyano-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′11)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]trizolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Cyano-3-((8′-methyl-1′, 1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]trizolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(4-Cyano-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]trizolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-((3-Methoxypropyl)amino)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(-3-((7′-((3-Hydroxypropyl)(methyl)amino)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(-3-((7′-((3-Methoxypropoxy)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(-3-((7′-((3-Hydroxyethyl)(methyl)amino)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(4-Methyl-((7′-((2-morpholinoethyl)amino)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-41′,1′-Dioxido-7′-((2-(piperidin-1-yl)ethyl)amino)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(Butylamino)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(3-((7′-((3-Hydroxypropyl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-((3-Hydroxypropyl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(3-((7′-((3-Hydroxypropyl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(3-((7′-(((R)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(3-((7′-(((S)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(((R)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(3-((7′-(((R)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(((S)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(3-((7′-(((S)-4-Hydroxybutan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(((S)-4-Hydroxybutan-2-yl)amino)-8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4[triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(((R)-3-Hydroxy-3-methylbutan-2-yl)amino)-8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((7′-(((1s,3S)-3-Hydroxycyclobutyl)amino)-8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido3-(3-((7′-(((*S)-4-hydroxybutan-2-yl)amino)-8′-methyl-1′,1′-dioxido-7′-(2-(piperi din-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-3-(3-((7′-(((*S)-4-hydroxybutan-2-yl)amino)-8′-methyl-1′,1′-dioxido-7′-(2-(piperi din-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(3-((7′-(3-((2-Hydroxyethyl)amino)-3-oxopropyl)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(3*R)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(3*S)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
3-(5,8-Dimethyl-3)-(trifluoromethyl)-[1,2,4-triazolo[4,3-α]pyridine-7-yl)-3-(3-(((*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methylpropanoic acid;
(3*R)-3-(5,8-Dimethyl-3)-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyridine-7-yl)-3-(3-(((*S)-5,5-dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methylpropanoic acid;
(3*S)-3-(5,8-Dimethyl-3)-(trifluoromethyl)-[1,2,4-triazolo[4,3-α]pyridine-7-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2-methylpropanoic acid;
(R/S)-3-(3-(((*S)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((*S)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((*S)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-4(*R)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((*R)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((*R)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((*S)-5,5-Dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-4(*R)-5,5-Dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((*R)-5,5-Dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((*R)-5,5-Dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-(((S)-5,5-Dioxido-7a, 8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-[3-[(5,5-Dioxo-7a,8,9,10-tetrahydro-7H-pyrrolo[2,1-d][1,2,5]benzothiadiazepin-6-yl)methyl]-4-methyl-phenyl]-3-(1-ethyl-4-methyl-benzotriazol-5-yl)propanoic acid;
(*R)-3-[3-[(5,5-Dioxo-7a,8,9,10-tetrahydro-7H-pyrrolo[2,1-d][1,2,5]benzothiadiazepin-6-yl)methyl]-4-methyl-phenyl]-3-(1-ethyl-4-methyl-benzotriazol-5-yl)propanoic acid;
(R/S)-3-3-[(4,4-Dimethyl-1,1-dioxo-3H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl]-4-methyl-phenyl]-3-(1-ethyl-4-methyl-benzotriazol-5-yl)propanoic acid;
(R/S)-3-(3-[(4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(34(S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(3-4-[4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-[(4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-4(R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl)-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl)-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl)-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-(difluoromethyl)-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(6-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-5-methylpyridin-2-yl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(64(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-5-methylpyridin-2-yl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(6-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-5-methylpyridin-2-yl)propanoic acid;
(R/S)-3-(4-Methyl-3-(((*S)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-3-(((S)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(4-Methyl-3-(((*S)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(4-Methyl-3-(((*R)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-34(*R)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(4-Methyl-3-(((*R)-9-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-pyrazino[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(4-Methyl-3-45′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-3,5′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(4-Methyl-3-((8′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-3-(((*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(4-Methyl-3-(((*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-4(R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(34(R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(3*S)-3-(3-((3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-4-Ethyl-8-methyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-48′-Chloro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-Cyano-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-Chloro-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-5,5-Dioxido-3-(trifluoromethyl)-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(34(*R)-5,5-Dioxido-3-(trifluoromethyl)-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-48′-Cyano-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-48′-Carbamoyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-2-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-2-Carbamoyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-2-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-2-Carbamoyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((S)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-Methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-[1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-((1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-benzo[f]pyrido[2,1-d][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-34(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*R)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-(((*R)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-4(*R)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-45′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-45′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(4-methyl-3-45′-methyl-1′,1′-dioxido-5′H-spiro[cyclopropane-1,4′-pyrido[2,3-f][1,2,5]thiadiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(R/S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-5-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*S)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-5-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-3-(1-Cyclopropyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethyl-3-(6-methyl-548′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-48′-fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(34(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(1-(Cyclopropylmethyl)-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((*R)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(R/S)-3-(641,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(6-((1,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(6-((1,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(641′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′11)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(641′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(6-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(R/S)-3-(6-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(6-41′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(6-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(7-(Difluoromethoxy)-1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-(((R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-4-Ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathi azepin-2-yl)methyl)-4-methylphenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*g)-3-(3-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-5,5-Dioxido-7a, 8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*S)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-ol][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydrobenzo[pyrrolo[2,1-4][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-ol][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydrobenzopyrrolo[2,1-4-[1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-[(4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(34(S)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((S)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-5,5-Dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydrobenzo[f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-ethyl-8-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-[4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((4,4-Dimethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-((1,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2 (31/)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*g)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9-tetrahydro-6H-azeto[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*S)-5,5-Dioxido-7,7a, 8,9-tetrahydro-6H-azeto[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-5,5-Dioxido-7,7a,8,9-tetrahydro-6H-azeto[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-5,5-Di oxido-7,7a,8,9-tetrahydro-6H-azeto[2,1-d]pyrido[2,3-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(6-(((R)-5,5-Dioxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(6-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(3-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-benzo[f]pyrido[2,1-d][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(34(*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-benzo[f]pyrido[2,1-d][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(6-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(6-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
3-(6-4(*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(6-4(*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*R)-3-(64(*R)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid;
(*S)-3-(4-methyl-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(4-methyl-3-(((*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(34(*S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((8′-Fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((3-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(371)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(371)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((7′-(2-morpholinoethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((7′-(2-morpholinoethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-41′,1′-Dioxidospiro[piperidine-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(341′,1′-Dioxidospiro[piperidine-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-41′,1′-Dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-Dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[piperidine-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[piperidine-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((7′-(3-((2-(2-Aminoethoxy)ethyl)amino)-3-oxopropyl)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((7′-(3-((2-(2-aminoethoxy)ethyl)amino)-3-oxopropyl)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(347′-(2-(4,4-Difluoropiperidin-1-yl)ethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α][pyridine-7-yl)propanoic acid;
(*R)-3-(347′-(((1R,3R)-3-Hydroxycyclobutyl)amino)-8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-8′-methyl-7′-(((R-1-morpholinopropan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-7′-morpholinopropan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-7′-(((1-morpholinopropan-2-yl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-7′-((2-morpholinoethyl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-7′-((2-morpholinoethyl)amino)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′ 1-(pyrrolidine-1-yl)propan-2-yl)amino)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-Dioxido-7′-(2-(piperazin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a][pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-(8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-4-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a][pyridine-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a][pyridine-7-yl)propanoic acid;
(*S)-3-(3-1′,1′-Dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a][pyridine-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridine-7-yl)-2,2-dimethyl-3-(4-methyl-3-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridine-7-yl)-2,2-dimethyl-3-(4-methyl-3-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
3-(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-((1-piperidin-1-yl)propan-2-yl)amino)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridine-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-((7′-(2-(4-Methoxypiperidin-1-yl)ethoxy)-8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridine-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(((S)-1-piperidin-1-yl)propan-2-yl)amino)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-1′,1′-Dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-1′,1′-Dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-(((*S)-8′-methyl-1′,1′-dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(4-methyl-3-(((*R)-8′-methyl-1′,1′-dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*S)-1′,1′-Dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-1′, l′-Dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-(((*S)-8′-methyl-1′,1′-dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-(((*R)-8′-methyl-1′,1′-dioxido-4,5-dihydro-2H-spiro[furan-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-4/[1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((R)-5,5-Dioxido-7a,8,9,10-tetrahydropyrido[2,3-J]pyrrolo[2,1-4/[1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((8′-fluoro-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((8-fluoro-1,1-dioxido-2′,3′,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(3H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(3 S*)-3-(3-((8-fluoro-1,1-dioxido-2′,3,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(31/)-yl)methyl)-4-methylphenyl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*S)-3-cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(344,4-dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*R)-3-(3-[(4,4-dimethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-2,2-difluoro-3-(3-((8-fluoro-1,1-dioxido-2′,3′,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(3H)-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(*S)-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(((R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(R)-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-((10,10-Difluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*S)-10,10-Difluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-10-difluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*S)-10,10-Difluoro-5,5-dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-10,10-Difluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(((*R)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*S)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*S)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(*S)-5,5-dioxido-7a,8,10,11-tetrahydro-[1,4]oxazino[3,4-d]pyrido[2,3-f][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(34(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(((R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-pyrido[2,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-[1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(((*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(((*S)-7a-methyl-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)phenyl)propanoic acid;
3-(6-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-3-(641′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-41′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-((1′,1′-Dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-((1,1-Dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-[1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-((1,1-dioxidospiro[benzo[b][1,4,5]oxathiazepine-4,3′-oxetan]-2(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-(((*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-(((*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-4(*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-(((*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-(((*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)pyridin-2-yl)propanoic acid;
3-(6-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-((1′,1′-Dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-(((*S)-3-Fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*S)-3-Fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*S)-3-Fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(((*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(((*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(((*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
3-(6-(((*S)-3-Fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(3*S)-3-(6-4(S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(3*R)-3-(6-(((*S)-3-Fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-2-methyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(6-((8′-Fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(6-((8′-Fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-((8′-Fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*S)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-4(*R)-3-fluoro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)propanoic acid;
(3*S)-3-(8-Ethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2-methyl-3-(4-methyl-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(3*S)-2-Methyl-3-(4-methyl-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(3*S)-3-(8-Ethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2-methyl-3-(4-methyl-3-(((*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*S)-3-(8-Ethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*R)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
(*S)-3-(8-Ethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-4(*S)-3-methyl-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)phenyl)propanoic acid;
3-(6-((3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*S)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(6-(((*R)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*S)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(6-(((*R)-3-Chloro-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-5-methylpyridin-2-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8-fluoro-1,1-dioxido-2′,3′,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(8-fluoro-1,1-dioxido-2′,3′,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(31/)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8-fluoro-1,1-dioxido-2′,3′,5′,6′-tetrahydrospiro[benzo[b][1,4,5]oxathiazepine-4,4′-pyran]-2(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8′-fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8′-fluoro-1′, 1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8′-fluoro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-((8′-Chloro-1′,1′-di oxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)propanoic acid;
(*S)-3-(3-((8′-Chloro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((8′-Chloro-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-(3-((8′-fluoro-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*S-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((8′-fluoro-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-48′-fluoro-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-48′-methyl-l′, l′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(4-methyl-3-(3((8′-methyl-1′, l′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(4-Methyl-3-((7′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((*R)-3-Cyano-5,5-di oxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((*R)-3-Cyano-5,5-di oxido-7a, 8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((*R)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-(((S)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(((S)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f]pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-(((S)-3-Cyano-5,5-dioxido-7a,8,9,10-tetrahydropyrido[2,3-f[pyrrolo[2,1-d][1,2,5]thiadiazepin-6(7H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(2*S,3*R)-2-Methyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(371)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(2*R,3*R)-2-Methyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(371)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
3-(3-4(*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanamide;
(*S)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanamide;
(*R)-3-(3-(((*S)-5,5-Dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-4-methylphenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanamide;
3-(3-48′-Carbamoyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-48′-Carbamoyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(348′-Carbamoyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(2S,3*R)-3-(3-(Trifluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(341′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2-methylpropanoic acid;
(R/S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(5-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-6-methylpyridin-3-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3 yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-3-(5-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-6-methylpyridin-3-yl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(8-Methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3 yl)methyl)pyridin-3-yl)propanoic acid;
(R/S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-41′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(R/S)-3-(5-41′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(5-((1′,1′-Dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(R/S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-3-yl)propanoic acid;
(R/S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-47′-(2-morpholinoethoxy)-1′,1′-di oxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*S-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-47′-(2-morpholinoethoxy)-1′,1′-di oxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((7′-(2-morpholinoethoxy)-1′,1′-di oxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)propanoic acid;
3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((7′-methoxy-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((7′-methoxy-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-47′-methoxy-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(R/S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-((8′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-3-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-methyl-5-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-3-yl)propanoic acid;
(R/S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-48′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-((8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-48′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-48′-methyl-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-48′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-4-48′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-((7′-(2-(3-fluoroazetidin-1-yl)ethoxy)-8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-2,2-dimethyl-3-(4-methyl-3-methyl-7′-(2-morpholinoethoxy)-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′,(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3,1′-dioxido-7′-(2-(pyrrolidine-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(3-amino-3-oxopropyl)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S) 2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-((1-(piperidin-1-yl)propan-2-yl)oxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′, (3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S) 2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(((*R)-1-(piperidin-1-yl)propan-2-yl)oxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′, (3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S) 2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(((*S)-1-(piperidin-1-yl)propan-2-yl)oxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′, (3H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(((*R)-1-(piperidin-1-yl)propan-2-yl)amino)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(2-(Azetidin-1-yl)ethoxy)-8′-methyl-1′,1′-dioxidospiro[cycl ° propane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(3-Cyclobutylamino-3-oxopropyl)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(2-Hydroxyethoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-((7′-(3-(3-Hydroxypropoxy)propoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(3-((7′-(3-(3-Hydroxypropoxy)propoxy)-1′,1′-dioxido-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(6-((1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethylpropanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(641′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-5-methylpyridin-2-yl)-2,2-dimethylpropanoic acid;
(*S)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-41′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-7-yl)propanoic acid;
(*S)-3-(3-(difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridine-7-yl)-3-(3-((1’, 1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(3-((1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethylpropanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-48′-methyl-1′,1′-dioxidospiro[oxetane-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxidospiro[azetidine-3,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-2,2-Dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-3-(5-methyl-6-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid (*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-4-((8′-methyl-1′,1′-dioxido-7′-(2-(piperidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*S)-3-(3-(Difluoromethyl)-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(5-methyl-6-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)-2,3,5,6-tetrahydrospiro[pyran-4,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)pyridin-2-yl)propanoic acid;
(*R)-3-(5-(((*R)-3-Cyano-5,5-dioxido-7,7a, 8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-3-(5-(((*S)-3-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d: 2′,3 f][1,2,5]thiadiazepin-6-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(54(*R)-3-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*S)-3-(5-(((*S)-3-Cyano-5,5-dioxido-7,7a,8,9,10,11-hexahydro-6H-dipyrido[2,1-d:2′,3′-f][1,2,5]thiadiazepin-6-yl)methyl)-6-methylpyridin-3-yl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid;
(*R)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)phenyl)-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridin-7-yl)propanoic acid (*S)-3-(3-47′-(2-(4-fluoropiperidin-1-yl)ethoxy)-8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-47′-(2-(4-fluoropiperidin-1-yl)ethoxy)-8′-methyl-1′,1′-dioxidospiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3′H)-yl)methyl)-4-methylphenyl)-2,2-dimethyl-3-(8-methyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-α]pyridine-7-yl)propanoic acid;
(*S)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-48′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid;
(*R)-3-(3-Cyclopropyl-8-methyl-[1,2,4]triazolo[4,3-α]pyridin-7-yl)-2,2-dimethyl-3-(4-methyl-3-((8′-methyl-1′,1′-dioxido-7′-(2-(pyrrolidin-1-yl)ethoxy)spiro[cyclopropane-1,4′-pyrido[2,3-b][1,4,5]oxathiazepin]-2′(3H)-yl)methyl)phenyl)propanoic acid; and
pharmaceutically acceptable salts thereof.