Patent ID: 11965823
Assignee: FOSS ANALYTICAL A/S
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method of correcting for an amplitude change in an output of a spectrometric instrument due to variations in an optical path length through a sample holder, the method comprising:
exposing an unknown sample in the sample holder to electromagnetic radiation at a plurality of wavenumbers;
detecting, by the spectrometric instrument, electromagnetic absorption intensities in the unknown sample at the plurality of wavenumbers;
providing, to a computer device, associated with the spectrometric instrument the detected electromagnetic absorption intensities indexed against wavenumber as spectral data;
generating, by the computer device, absorbance values relative to a zero material sample from the spectral data;
applying, by the computer device, a mathematical transform (Icorr) to the generated absorbance values to correct for the amplitude change in the output of the spectrometric instrument;
wherein the method further includes
calculating, in the computer device, the mathematical transform (Icorr) by determining a difference (Δ(SBZ)/) between
a first derivative of a logarithmic transformation of spectral data (SBZ) from the zero material sample at a first wavenumber range (x1) (log10(SBZ(x1))/), and
a first derivative of a logarithmic transformation of the spectral data (SBZ) from the zero material sample at a second wavenumber range (x2) (log10(SBZ(x2))/), and

calculating, in the computer device, the mathematical transform (Icorr) as a function inversely dependent on the determined difference (Δ(SBZ)/).