Patent ID: 11873315
Assignee: THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  B | IPC B  C

Claim 6:
7. A compound having a structure represented by a formula:, wherein n is selected from 0 and 1;
wherein each of R101a and R101b is independently selected from hydrogen, halogen, —NO2, —CN, —OH, —SH, —NH2, C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C1-C4 haloalkyl, C1-C4 cyanoalkyl, C1-C4 hydroxyalkyl, C1-C4 haloalkoxy, C1-C4 alkoxy, C1-C4 thioalkyl, C1-C4 alkylthiol, C1-C4 aminoalkyl, C1-C4 alkylamino, and (C1-C4)(C1-C4) dialkylamino, provided that at least one of R101a and R101b is —OH, —SH, or C1-C4 alkylamino;
wherein each of R102a, R102b, and R102C is independently selected from hydrogen, halogen, —NO2, —CN, —OH, —SH, —NH2, C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C1-C4 haloalkyl, C1-C4 cyanoalkyl, C1-C4 hydroxyalkyl, C1-C4 haloalkoxy, C1-C4 alkoxy, C1-C4 thioalkyl, C1-C4 alkylthiol, C1-C4 aminoalkyl, C1-C4 alkylamino, and (C1-C4)(C1-C4) dialkylamino;
wherein R103 is selected from C4-C8 alkyl and Ar101, provided that when R103 is C4-C8 alkyl, then either
(a) at least one of R101a and R101b is —SH or C1-C4 alkylamino, or
(b) R101b is —OH;
wherein Ar101, when present, is selected from C6-C10 aryl and C5-C6 heteroaryl, and is substituted with 0, 1, 2, or 3 groups independently selected from halogen, —NO2, —CN, —OH, —SH, —NH2, C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C1-C4 haloalkyl, C1-C4 cyanoalkyl, C1-C4 hydroxyalkyl, C1-C4 haloalkoxy, C1-C4 alkoxy, C1-C4 thioalkyl, C1-C4 alkylthiol, C1-C4 aminoalkyl, C1-C4 alkylamino, (C1-C4)(C1-C4) dialkylamino, and phenyl;

wherein R104 is unsubstituted phenyl; and
wherein R105 is C1-C4 alkyl,
provided that when n is 0, R101b is —OH, and R103 is C6 aryl or C6 heteroaryl, then either:
(c) each of R102a and R102b is hydrogen, or
(d) one of R102a and R102b is hydrogen,

or a pharmaceutically acceptable salt thereof.