Patent ID: 11891405
Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A compound of formula (I), a stereoisomer thereof or a pharmaceutically acceptable salt thereof,, wherein,
ring B is selected from the group consisting of 5-10 membered heteroaryl and C6-10 aryl;
R1 is independently selected from the group consisting of halogen, —OH, —NH2, cyano, C1-6 alkyl and C1-6 alkoxy, wherein C1-6 alkyl or C1-6 alkoxy is optionally substituted with halogen;
m is 0, 1, 2, 3 or 4;
L is selected from the group consisting of —C(O)NH—, —NHC(O)—, —O—, —NH—, —S—, —C(O)O—, —OC(O)—, —S(O)2O— and —OS(O)2—;
R2 is independently selected from the group consisting of halogen, —OH, —NH2, cyano, C1-6 alkyl and C1-6 alkoxy, wherein C1-6 alkyl or C1-6 alkoxy is optionally substituted with halogen;
n is 0, 1, 2, 3 or 4;
R3 is selected from the group consisting of H, RaC(O)—, RaS(O)2— and Ra—;
R5 is independently selected from the group consisting of halogen, —OH, —NH2, cyano, C1-6 alkyl and C1-6 alkoxy;
p is 0, 1, 2 or 3;
R4 is selected from the group consisting of hydrogen, RaS(O)2—, (RaO)2P(O)— and RaC(O)—;
wherein Ra is independently selected from the group consisting of C2-6 alkynyl, C2-6 alkenyl, C1-6 alkyl, C3-6 cycloalkyl, (C1-6 alkyl)NH—, (C1-6 alkyl)2N—, 3- to 6-membered heterocycloalkyl, 5- to 10-membered heteroaryl and C6-10 aryl, wherein Ra is optionally substituted with (C1-6 alkyl)2N—, (C1-6 alkyl)NH—, hydroxy, amino, halogen or cyano.