Patent ID: 11879159
Assignee: BEIJING ORIGINPOLY BIO-TEC CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A composition for early detection of high-grade cervical lesions and cervical cancer, characterized in that: the composition includes FAM19A4 gene methylation primers, JAM3 gene methylation primers and PAX1 gene methylation primers and 1 pair of primers for internal reference gene GAPDH, wherein:
the sequence of the FAM19A4 gene methylation forward primer F is SEQ ID NO. 1,
the sequence of the FAM19A4 gene methylation reverse primer R is SEQ ID NO. 2;
the sequence of the JAM3 gene methylation forward primer F is SEQ ID NO. 3,
the sequence of the JAM3 gene methylation reverse primer R is SEQ ID NO. 4;
the sequence of the PAX1 gene methylation forward primer F is SEQ ID NO. 5,
the sequence of the PAX1 gene methylation reverse primer R is SEQ ID NO. 6;
the sequence of the internal reference gene GAPDH forward primer F is SEQ ID NO. 7, and
the sequence of the internal reference gene GAPDH reverse primer R is SEQ ID NO. 8.