Patent ID: 11883679
Assignee: NORTH CAROLINA STATE UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 22:
23. A kit comprising:
an ultrasound transducer effective to induce in vivo cavitation of a plurality of magnetic microbubbles (MMBs) in a target region of a subject,
a portable, targeted rotational magnetic field generator effective to accumulate MMBs in a target region and increase cavitation of the MMBs induced by the ultrasound transducer, and
instructions for using the ultrasound transducer and portable, targeted rotational magnetic field generator with a composition of MMBs and optional NDs to treat a subject, wherein the instructions describe the use of the ultrasound transducer to generate an acoustic frequency of about 100 kHz to about 5 MHz, with an ultrasound duty cycle of about 0.5% to about 25%, and an input voltage of about 10 Vpp to 250 Vpp.