Patent ID: 11865213
Assignee: MAPI PHARMA LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 8:
9. The long-acting parenteral pharmaceutical composition of claim 4, wherein the water-in-oil-in-water (w/o/w) double emulsion droplets are formed by a process comprising the steps of:
(i) dispersing an aqueous suspension or solution of semaglutide or a pharmaceutically acceptable salt thereof in a solution of a biodegradable carrier and the first surfactant in a water-immiscible volatile organic solvent, thereby obtaining a water-in-oil emulsion; and
(ii) dispersing said water-in-oil emulsion in a continuous external water phase comprising the second surfactant and the tonicity modifier, to form microparticles comprising water-in-oil-in-water (w/o/w) double emulsion droplets.