Patent ID: 11897775
Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION
Field: Measurement (Instruments)
Classification: CPC C  A  G | IPC A  C

Claim 0:
1. A nitric oxide-releasing material consisting of:
a mesoporous silica core having an outer surface, and
a plurality of moieties having a structure according to the following formula covalently bonded to the outer surface of the mesoporous silica core, where A is a S-nitrosothiol selected from the group consisting of S-nitroso-N-acetyl-penicillamine, S-nitroso-N-acetyl cysteine, S-nitroso-N-acetyl cysteamine, S-nitrosoglutathione, and methyl S-nitrosothioglycolate;
where R1 is a substituted or unsubstituted C1-C20 alkyl, a substituted or unsubstituted C1-C20 heteroalkyl, a substituted or unsubstituted C2-C20 alkenyl, a substituted or unsubstituted C2-C20 herteroalkenyl, a substituted or unsubstituted C1-C20 alkoxy, or a substituted or unsubstituted C1-C20 heteroalkoxy;
where each occurrence of R2 is independently a substituted or unsubstituted C1-C20 alkyl, a substituted or unsubstituted C1-C20 heteroalkyl, a substituted or unsubstituted C2-C20 alkenyl, a substituted or unsubstituted C2-C20 herteroalkenyl, a substituted or unsubstituted C1-C20 alkoxy, a substituted or unsubstituted C1-C20 heteroalkoxy, or a bond to an oxygen atom on the outer surface so long as at least one occurrence of R2 is a bond to an oxygen atom on the outer surface of the mesoporous silica core.