Patent ID: 11965218
Assignee: YALE UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C  G

Claim 10:
11. A method of determining whether a respiratory virus is involved in an active disease process compared with incidental detection, the method comprising:
a. analyzing a viral transport medium sample from the patient to determine a level of at least one nasal virus-induced molecule and a level of a housekeeping gene;
b. normalizing the level of the at least one nasal virus-induced molecule to the level of the housekeeping gene to determine a normalized level of the at least one nasal virus-induced molecule; and
c. comparing the normalized level of the at least one nasal virus-induced molecule with a predetermined reference level for the at least one nasal virus-induced molecule;
wherein the method further comprises determining the level of interferon lambda 1 (IFNL1) as an indicator of sample quality; and
wherein if the normalized level of the at least one nasal virus-induced molecule is above the reference level, the respiratory virus is determined to be in the active disease process.