Patent ID: 11951094
Assignee: AXIAL THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A

Claim 0:
1. A method for treating cancer in a subject in need thereof, comprising administering to the subject a compound of Formula (I):, or a pharmaceutically acceptable salt thereof, wherein:
R is:, wherein each R is substituted or unsubstituted; or
R is, L1 is a five-membered heteroarylene, or a bond;
G is:, X is —NH(CH2)m CH3, —NH(CH2)m-(substituted or unsubstituted Ph), or, Z is CH or N, provided that no more than one Z on any one ring is N;
each Z1 is independently —CH2— or —C(═O)—;
each Z2 is independently —O—, —S—, or —NH—;
L2 is a bond, —(CH2)m—, —CO—, —SO2—, —(C═O)NH—, or —(C═O)O—;
Y is —H, substituted or unsubstituted C1-16 alkyl, C1-16 alkyl-(substituted or unsubstituted Ph), —NH(CH2)mCH3, —SO2(CH2)13CH3, or substituted or unsubstituted C3-10 cycloalkyl;
W is H, hydroxyl, —OCH3, —O(CH2)mCH3, —NH(C═O)CH3—NH(C═O)(CH2)mCH3, —(C═O)—NH(CH2)mCH3, substituted or unsubstituted C1-16 alkyl, C1-16 alkyl-(substituted or unsubstituted Ph), —NH(CH2)mCH3, —N((CH2)mCH3)2, —N(CH3)(Y), or substituted or unsubstituted C3-10 cycloalkyl;
each m is independently 1-16;
each n is independently 1-3; and
each p is independently 3-8.