Patent ID: 11939574
Assignee: AUGMANITY NANO LTD
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 10:
11. The RNA origami nanostructure of claim 10, wherein: (I) the scaffold nucleic acid strands comprise the sequence as set forth in SEQ ID NO:1, a fragment thereof or an analog thereof, and the origami nanostructure comprises staple nucleic acid strands comprise the sequences set forth in (i) SEQ ID Nos: 2-55, (ii) SEQ ID Nos: 508-561, (iii) SEQ ID Nos: 655-695 or (iv) any combination of the sequences of (i) - (iii), and optionally further comprising staple oligonucleotides having the sequences set forth in (i) SEQ ID Nos 56-67, (ii) SEQ ID Nos: 562-573, or (iii) any combination of the sequences of (i) and (ii); (II) the scaffold nucleotide strands comprise the sequence set forth in SEQ ID NO:68, a fragment thereof, or an analog thereof, and the origami nanostructure comprises staple nucleotide sequences selected from the sequences as set forth in (i) SEQ ID NOs: 69-170 and optionally in SEQ ID NOs: 171-186, (ii) SEQ ID NOs: 360-437, or (iii) SEQ ID NOs: 438-500, wherein said RNA origami nanostructure is a cuboctahedron; or (III) the one or more scaffold nucleic acid strands comprise the sequence as set forth in SEQ ID NO:1 and/or at least one of said scaffold nucleic acids strands has the sequence as set forth in SEQ ID NO:68.