Patent ID: 11919902
Assignee: HIBERCELL, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The compound of claim 1 selected from the group consisting of:
1-(2′-amino-5′-(imidazo[1,2-a]pyridin-5-yl)[2,3′-bipyridin]-5-yl)pyrrolidin-2-one,
1-(2′-amino-5′-(benzo[d]thiazol-7-yl)[2,3′-bipyridin]-5-yl)pyrrolidin-2-one,
1-(2′-amino-5′-(thieno[2,3-b]pyridin-3-yl)-[2,3′-bipyridin]-5-yl)pyrrolidin-2-one,
1-(4-(5-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(2′-amino-5′-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-[2,3′-bipyridin]-5-yl)pyrrolidin-2-one,
1-(4-(5-(2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-(4-(5-(1-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1-(2-hydroxyethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2H-pyrazolo[4,3-b]pyridin-7-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-(1-hydroxyethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
N,N-dimethyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(5-methoxy-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
7-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
7-(cyclopropylmethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carbonitrile,
1-(4-(5-(2H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-([3,4′-bipyridin]-5-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-chloro-2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-methyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-methyl-N-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)-[3,4′-bipyridin]-2′-yl)acetamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one,
1-(4-(5-(1-methyl-5-(piperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
methyl 4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide,
N-(2-methoxyethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(2-(morpholine-4-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N,N,1-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide,
N-benzyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-4-ylmethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-isobutyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(2-(pyrrolidine-1-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-phenethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(pyridin-3-phenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-3-ylmethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-2-ylmethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N,N-dimethyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-cyclopropyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1,6-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one,
N-(2-(1H-imidazol-2-yl)ethyl)-4-(5-(4-(pyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-(benzo[d]oxazol-2-ylmethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
2-isopropyl-N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
2-isopropyl-N,N,1-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(pyridin-2-yl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(pyridin-4-yl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
methyl 4-(5-(2-oxopyrrolidin-1-yl)[2,3-b]pyridinyl-5′-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
N,N,1,2-tetramethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
N,N,2-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
N-(2-(2H-tetrazol-5-yl)ethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
2-cyclopropyl-N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
1-(4-(5-(1H-pyrrolo[3,2-b]pyridin-1-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N,N-dimethyl-1-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridine-6-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(pyrazin-2-yl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(thiazol-2-yl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(6-amino-[3,4′-bipyridin]-5-yl)phenyl)pyrrolidin-2-one,
N-(cyclopropylmethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-7-(cyclopropylmethyl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one,
1-(1-methyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolidin-2-one,
1-(4-(2-amino-5-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-methoxyethyl)furo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(6-methoxy-2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-methylfuro[2,3-b]pyridine-2-carboxamide,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(cyclopropylmethyl)furo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one,
N-(2-methoxyethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
1-(4-(2-amino-5-(1-methyl-5-(2-oxopyrrolidin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(2-amino-5-(7-methoxy-2H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N,1,6-trimethyl-7-oxo-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-5-carboxamide,
N,N,1,6-tetramethyl-7-oxo-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-5-carboxamide,
N-(2-(1H-pyrrol-2-yl)ethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
2-cyclopropyl-N,N,1-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
1,6-dimethyl-7-oxo-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-5-carboxamide,
N,N,1-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-sulfonamide,
1-(4-(5-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-8-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N,N,1-trimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
N-methyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
1-(4-(5-(6-cyclopropyl-2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(4-(methoxymethyl)[3,4-b]pyridinyl-5-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N,1-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,
1-(4-(5-(5-ethoxy-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7-methoxy-2H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one,
methyl 4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
1-(4-(4-methyl-[3,4′-bipyridin]-5-yl)phenyl)pyrrolidin-2-one,
1-(4-(2-amino-5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(6-amino-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(oxetan-3-yl)furo[2,3-b]pyridine-2-carboxamide,
1-(4-([3,4′-bipyridin]-5-yl)-3-methylphenyl)pyrrolidin-2-one,
1-(4-(5-(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(6-methyl-[3,4′-bipyridin]-5-yl)phenyl)pyrrolidin-2-one,
1-[4-[5-(7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-3-pyridyl]phenyl]pyrrolidin-2-one,
1-(4-(5-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-(2-methoxypropan-2-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7-methoxy-1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-[4-[5-(3-bromo-7,8-dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl)-3-pyridyl]phenyl]pyrrolidin-2-one,
1-[4-[5-[3-(1-Hydroxyethyl)-7,8-dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl]-3-pyridyl]phenyl]pyrrolidin-2-one,
1-[4-[5-(7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-5-yl)-3-pyridyl]phenyl]pyrrolidin-2-one,
1-(4-(5-(imidazo[1,2-a]pyrimidin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
5-ethyl-6-methyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one,
1-(4-(5-(5-(2-oxopyrrolidin-1-yl)furo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-(1-hydroxyethyl)furo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
5-isopropyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one,
N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-5-carboxamide,
1-(4-(5-(5-cyclopropyl-1H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
6-(2-hydroxyethyl-2,5-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one,
(S)-7-methyl-4-(5-(4-(4-methyl-2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
(R)-7-methyl-4-(5-(4-(4-methyl-2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-(4-(5-(5-(methoxymethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-(4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)pyrimidin-2-yl-cyclobutanecarboxamide, 6-ethyl-5-methyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7 (4H)-one,
1-(4-(5-(8-cyclobutyl-7H-purin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-7-(pyridin-2-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
4-(5-(4-(4,4-dimethyl-2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-7-methyl-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
methyl 5-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
(S)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)-3-methylphenyl)pyrrolidin-2-one,
(R)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)-3-methylphenyl)pyrrolidin-2-one,
1-(4-(5-(5-(1-hydroxyethyl)-1-methy 1-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)-3-methylphenyl)pyrrolidin-2-one,
1-(4-(5-(2-cyclopropyl-5-(1-hydroxyethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
(S)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-methylpyridin-3-yl)phenyl)pyrrolidin-2-one,
(R)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-methylpyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-(1-hydroxy ethyl)-1-methy 1-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-methylpyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(thieno[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
(R)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
(S)-1-(4-(5-(5-(1-hydroxyethyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-methyl-4-(4-methyl-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
N,N-dimethyl-3-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-sulfonamide,
methyl 5-chloro-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
N-(oxetan-3-yl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
N,N-dimethyl-4-(4-methyl-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-methylpyridin-3-yl)phenyl)pyrrolidin-2-one,
N,N-dimethyl-4-(5-(2-methyl-4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)-3-methylphenyl)pyrrolidin-2-one,
methyl 4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxylate,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(2-(thiazol-5-yl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(7,8-dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1-methyl-1,5,6,7-tetrahydrocyclopenta[b]pyrazolo[4,3-e]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
methyl 4-(4-methyl-5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
2-(1-methyl-7-oxo-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1,7-dihydro-6H-pyrazolo[3,4-c]pyridin-6-yl)acetonitrile,
methyl 4-(5-(2-methyl-4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
isopropyl 4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxylate,
1-(4-(5-(1-methyl-3-(pyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1H-benzo[d]imidazol-1-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-methyl-4-(5-(2-methyl-4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)furo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(7-methoxy-2-methyl-2H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
ethyl 4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid, isopropyl 4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate,
1-(4-(5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1H-pyrazolo[4,3-b]pyridin-7-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-8-yl)-3-pyridyl)phenyl)pyrrolidin-2-one,
1-(4-(5-(4-Pyridyl)-3-pyridyl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-chloro-1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-cyclopropyl-1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7-methoxy-1H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(1-methyl-3-(2-methylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(6-methoxy-1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(4-(5-(4-(2-Oxopyrrolidin-1-yl)phenyl[-3-pyridyl]-5,6-dihydropyrrolo[3,4-b]pyridin-7-one,
1-(4-(2-amino-5-(7-methoxy-1H-pyrazolo[3,4-c]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7-methoxy-2-methyl-pyrazolo[3,4-c]pyridin-4-yl)-3-pyridyl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7,8-Dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl)-3-pyridyl)phenyl)pyrrolidin-2-one,
1-(4-(5-(4-Methyl-2,4,5-triazatricyclo[7.3.0.03,7]dodeca-1,3(7),5,8-tetraen-8-yl)-3-pyridyl)phenyl)pyrrolidin-2-one,
1-(4-(5-(5-methyl-2-(piperidin-1-yl)thiazolo[4,5-d]pyrimidin-7-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
(R)-7-methyl-4-(5-(4-(2-methyl-5-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-(4-(5-(3-methylisoxazolo[5,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
7-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-(4-(2-amino-5-(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-methyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-phenyl-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N,3-dimethyl-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-((5,6-dimethyl-1H-benzo[d]imidazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(6-amino-5-(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-((4-methyl-1H-benzo[d]imidazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-(benzo[d]thiazol-2-ylmethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-((6-methyl-1H-benzo[d]imidazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-((1-methyl-1H-benzo[d]imidazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-((1H-benzo[d]imidazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2-(6-methyl-3,4-dihydro-2H-benzo[b][ 1,4]oxazine-4-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-N-phenyl-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-(oxazol-2-ylmethyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
7-(1,5-dimethyl-1H-pyrazol-3-yl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-8,9-dihydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-6(7H)-one,
1-(4-(5-(7-cyclopropyl-[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-(2-aminopyrimidin-5-yl)imidazo[1,2-a]pyrimidin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7-methyl-[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-(6-aminopyridin-3-yl)imidazo[1,2-yl]pyrimidin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2-cyclopropyl-5-(2-hydroxypropan-2-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2-(7-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-4-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-([1,2,4]triazolo[4,3-a]pyrimidin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-(pyrimidin-5-yl)imidazo[1,2-a]pyrimidin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-(5-(1-methyl-5-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-yl)acetamide,
1-(4-(5-(3-(pyridin-3-yl)imidazo[1,2-a]pyrimidin-6-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-(6-aminopyridin-3-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-(5-(1-methyl-5-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl)acetamide,
1-(4-(5-(3-(1-hydroxyethyl)-7,8-dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-bromo-7,8-dihydro-6H-pyrido[3,2-b]pyrrolizin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(3-(2-aminopyrimidin-5-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
N-((4,5-dimethyloxazol-2-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide,
1-(4-(5-(2-((2S,4R)-2-(2-hydroxypropan-2-yl)-4-methylpyrrolidine-1-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one,
1-(4-(5-(2-(3-cyclopropyl-3-hydroxypiperidine-1-carbonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)pyridin-3-yl)phenyl)pyrrolidin-2-one, and
N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-4-yl)methyl)-4-(5-(4-(2-oxopyrrolidin-1-yl)phenyl)pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide; or
a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof.