Patent ID: 11891434
Assignee: CHUGAI SEIYAKU KABUSHIKI KAISHA
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C  G

Claim 25:
26. The method of claim 1, wherein the FcRn-binding domain is a modified Fc domain that has FcRn-binding activity at pH 7.4, wherein the amino acid sequence of the modified Fc domain varies from the sequence of a wild type Fc domain at one or more of positions 248, 250, 252, 254, 255, 256, 257, 258, 265, 286, 289, 297, 303, 305, 307, 308, 309, 311, 312, 314, 315, 317, 332, 334, 360, 376, 380, 382, 384, 385, 386, 387, 389, 424, 428, 433, 434, and 436 (EU numbering).