Patent ID: 11918571
Assignee: PRAXIS PRECISION MEDICINES, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 15:
16. The method of claim 1, wherein the compound of Formula (I) is a compound of Formula (I-a):, or pharmaceutically acceptable salt thereof, wherein:
each of X, Y, and Z is CR′;
R′ is hydrogen or C1-6 alkyl;
R1 is selected from the group consisting of hydrogen, deuterium and C1-6 alkyl, wherein the C1-6 alkyl is optionally substituted with one or more of R4;
each R3a is independently selected from the group consisting of C1-6 alkyl, C3-8 carbocyclyl, fluoro, chloro and —ORc, wherein the C1-6 alkyl and C3-8 carbocyclyl are optionally substituted with one or more R5;
each R4 is independently selected from the group consisting of fluoro, oxo, cyano, nitro and —ORc;
each R5 is independently selected from the group consisting of C1-6 alkyl, halogen, oxo, cyano, nitro and —ORc, wherein the C1-6 alkyl is optionally substituted with one or more R7;
n is selected from the group consisting of 0, 1 and 2;
each Rc is independently selected from the group consisting of hydrogen, C1-6 alkyl and C3-8 carbocyclyl, wherein the C1-6 alkyl and C3-8 carbocyclyl are optionally substituted with one or more R6;
each R6 is independently selected from the group consisting of C1-6 alkyl, C3-8 carbocyclyl, halo, cyano, nitro and —OH; and
each R7 is independently selected from the group consisting of C1-6 alkyl, halogen and oxo.