Patent ID: 11964973
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 1:
2. The compound according to claim 1 or a salt thereof, wherein:
R1 is H, F, Cl, Br, —CN, C1-3 alkyl substituted with zero to 4 R1a, cyclopropyl substituted with zero to 3 R1a, C1-3 alkoxy substituted with zero to 3 R1a, —C(O)NRaRa, —NRaRa, —S(O)nCH3, or —P(O)(CH3)2;
each R1a is independently F, Cl, or —CN;
each Ra is independently H or C1-3 alkyl;
R2 is H, C1-2 alkyl substituted with zero to 2 R2a, or C2-3 alkenyl substituted with zero to 2 R2a;
each R2a is independently F, Cl, —CN, —OH, —O(C1-2 alkyl), cyclopropyl, C3-4 alkenyl, or C3-4 alkynyl;
R3 is H, F, Cl, Br, —CN, C1-2 alkyl, C1-2 fluoroalkyl, C3-4 cycloalkyl, —NO2, or pyridinyl substituted with zero to 1 R3a;
R4a is C3-6 cycloalkyl, oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, piperidinyl, piperazinyl, morpholinyl, phenyl, naphthalenyl, furanyl, pyranyl, pyrrolyl, pyrazolyl, imidazolyl, isoxazolyl, oxazolyl, oxadiazolyl, triazolyl, indolyl, indazolyl, phthalazinyl, pyridazinyl, pyridinyl, pyrimidinyl, pyrazinyl, triazinyl, benzooxazolyl, benzothiazolyl, benzoimidazolyl, quinolinyl, isoquinolinyl, quinoxalinyl, quinazolinyl, naphthyridinyl, or dihydrobenzo[b][1,4]dioxepinyl, each substituted with zero to 3 R4b;
each R4b is independently F, Cl, Br, —CN, —OH, C1-6 alkyl, C1-2 fluoroalkyl, C1-3 hydroxyalkyl, —(CH2)1-2O(C1-3 alkyl), C1-4 alkoxy, —O(C1-3 hydroxyalkyl), C1-2 fluoroalkoxy, —C(O)(C1-3 alkyl), —C(O)OH, —C(O)O(C1-3 alkyl), —C(O)NH2, —C(O)NH(C1-3 alkyl), —C(O)N(C1-3 alkyl)2, —NRcRc, —S(O)2(C1-2 alkyl), C3-6 cycloalkyl, or —CRcRc(phenyl);
R4c is H, C1-4 alkyl, or R4a;
R4d is H or C1-4 alkyl;
each R5 is independently F, —CN, —OH, C1-5 alkyl substituted with zero to 4 Rg, C1-3 alkoxy substituted with zero to 3 Rg, C2-3 alkenyl substituted with zero to 4 Rg, C2-3 alkynyl substituted with zero to 4 Rg, —(CH2)1-2(C3-4 cycloalkyl substituted with zero to 4 Rg), phenyl substituted with zero to 3 Rg, oxadiazolyl substituted with zero to 3 Rg, pyridinyl substituted with zero to 3 Rg, —(CH2)1-2 (heterocyclyl substituted with zero to 4 Rg), —O(CH2)1-2(heterocyclyl substituted with zero to 4 Rg), —(CH2)1-2NRcC(O)(C1-4 alkyl), —(CH2)1-2NRcC(O)O(C1-4 alkyl), —(CH2)1-2NRcS(O)2(C1-4 alkyl), —C(O)(C1-4 alkyl), —C(O)OH, —C(O)O(C1-4 alkyl), —C(O)O(C3-4 cycloalkyl), —C(O)NRaRa, or —C(O)NRa(C3-4 cycloalkyl); and
each R6 is H, F, or —CH3.