Patent ID: 11965183
Assignee: OXFORD NANOPORE TECHNOLOGIES PLC
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 12:
13. The method of claim 1, wherein the Dda helicase comprises a substitution corresponding to: H82N; H82Q; H82W; N88R; N88H; N88W; N88Y; P89L; P89V; P89I; P89E; P89T; P89F; D121H; D121Y; D121K; V150I; V150L; V150N; V150W; V150H; P152W; P152F; P152Y; P152H; P152I; P152L; P152V; F240W; F240Y; F240H; F276W; F276R; F276K; F276H; S287K; S287R; S287W; S287F; H396Y; H396F; H396Q; H396K; Y415W; Y415R; F98W/H82N; F98W/H82Q; F98W/H82W; F98W/N88R; F98W/N88H; F98W/N88W; F98W/N88Y; F98W/P89L; F98W/P89V; F98W/P89I; F98W/P89T; F98W/P89F; F98W/D121H; F98W/D121Y; F98W/D121K; F98W/V150I; F98W/V150L; F98W/V150N; F98W/V150W; F98W/V150H; F98W/P152W; F98W/P152F; F98W/P152Y; F98W/P152H; F98W/P152I; F98W/P152L; F98W/P152V; F98W/F240W; F98W/F240Y; F98W/F240H; F98W/F276W; F98W/F276R; F98W/F276K; F98W/F276H; F98W/S287K; F98W/S287R; F98W/S287W; F98W/S287F; F98W/H396Y; F98W/H396F; F98W/H396Q; F98W/Y415W; or F98W/Y415R.