Patent ID: 11884613
Assignee: CHIROGATE INTERNATIONAL INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 5:
6. The process according to claim 4, wherein the intramolecular cyclization reaction comprises the steps of:
(a) hydrobornation of the compound of Formula 3a with a boron reagent, followed by oxidation with basic hydrogen peroxide to form an alcohol compound of Formula 4a-1:, wherein P, X and Y are as defined in claim 4;

(b) sulfonylation of the compound of Formula 4a-1 in the presence of a base with a sulfonyl donor to form a compound of Formula 4a-2:, wherein Z is a sulfonyl group; and P, X and Y are as defined above; and

(c) intramolecular alkylation of the compound of Formula 4a-2 in the presence of a base to form the compound of Formula 4a.