Patent ID: 11866398
Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  B | IPC B  C

Claim 0:
1. A method for producing at least one Δ12-Prostaglandin J product represented by Formula (IV),, wherein: Rz is selected from, and wherein at least one carbon-carbon double bond has a Z/E-selectivity of 95/5, or 96/4, or 97/3, or 98/2, or 99/1, or >99/<1;
comprising, submitting an alcohol product of Formula (III), to oxidation conditions; wherein the alcohol product of Formula (III) is formed during a cross-metathesis reaction between a substrate represented by Formula (II), and cis-5-octen-1-ol in the presence of a ruthenium olefin metathesis catalyst; and wherein Rv is selected from,