Patent ID: 11878975
Assignee: BRISTOL-MYERS SQUIBB COMPANY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. A compound according to claim 5 or a salt thereof, wherein said compound is:
(1R,2S)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-(octahydrocyclopenta[c]pyrrol-4-yl)cyclopropane-1-carboxamide (453, 457);
(2,5-diazabicyclo[2.2.1]heptan-2-yl)((1R,2S)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)cyclopropyl)methanone (454);
(hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)((1R,2S)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)cyclopropyl)methanone (455);
(1R,2S)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-(piperidin-4-yl) cyclopropane-1-carboxamide (456);
(1R,2R)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-(1-isopropylpiperidin-4-yl)cyclopropane-1-carboxamide (458);
(1R,2R)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-methyl-N-(quinuclidin-2-yl)cyclopropane-1-carboxamide (459, 463);
(1R,2R)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-(quinuclidin-2-yl) cyclopropane-1-carboxamide (460-461);
(1R,2R)-2-(3-isopropyl-2-(2-methylpyridin-4-yl)-1H-indol-5-yl)-N-methyl-N-(piperidin-4-yl)cyclopropane-1-carboxamide (462);
3-isopropyl-2-(2-methylpyridin-4-yl)-5-((1R,2R)-2-(pyrrolidin-1-ylmethyl) cyclopropyl)-1H-indole (464); or
N-isopropyl-3-(3-isopropyl-2-(8-methoxy-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-indol-5-yl)-N-methylcyclopentan-1-amine (275 to 278).