Patent ID: 11931719
Assignee: PURIDIFY LTD.
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 0:
1. A functionalised chromatography medium, comprising:
i) at least one non-woven layer of polymeric nanofibres comprising a plurality of nanofibre-nanofibre fusion points;
ii) a grafted polymer coating covering said polymeric nanofibres and said nanofibre-nanofibre fusion points, wherein the grafted polymer coating comprises polymer molecules which are single-point covalently tethered to said polymeric nanofibres, and wherein the polymer molecules comprise glycidol monomer residues formed from a plurality of compounds of formula, , and
iii) a plurality of ligand groups covalently bound to said grafted polymer coating, wherein said ligand groups are capable of interacting with a target biomolecule.