Patent ID: 11872324
Assignee: GEORGIA TECH RESEARCH CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 19:
20. A composition comprising a construct, said construct comprising a biocompatible substrate having a first surface, wherein the biocompatible substrate is selected from a synthetic polymer, a ceramic, a metal, an alloy and composites thereof, a material surface comprising an alkyl acrylate polymer deposited on said first surface, wherein the alkyl acrylate polymer is capable of supporting the formation of a physiological fibrillar network of FN adsorbed on its surface, fibronectin (FN) adsorbed on said material surface, wherein the FN forms a physiological fibrillar network of FN presenting colocalized growth factor binding domains and integrin binding domains, and a growth factor (GF) adsorbed on said FN, wherein said growth factor is capable of binding FNIII12-14; and a murine mesenchymal stem cell (MSC).