Patent ID: 11890371
Assignee: PETVIVO HOLDINGS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of treating or enhancing the function of a joint comprising:
administering a plurality of particles to the synovial space or the area proximal to the periosteum in the joint of a patient, said particles comprising one or more biocoacervate material(s) precipitated from a solution comprising effective proportions of two or more soluble biocompatible proteins, one or more glycosaminoglycans and one or more biocompatible solvents,
wherein the biocoacervate material(s) are shape-holding solid precipitate,
wherein all or a portion of the particles are crosslinked with one or more crosslinking agents,
wherein the two or more soluble biocompatible proteins comprise Type I collagen and elastin,
wherein the one or more glycosaminoglycans comprise heparin,
wherein the biocoacervate material(s) comprise a ratio of about 2 parts of elastin to about 1 part of the one or more glycosaminoglycans to at least one of: about 7 parts of Type I collagen, and about 7.5 parts of Type I collagen, and
wherein the particles have a size of approximately 500 nm to 1000 μm.