Patent ID: 11857563
Assignee: NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of treating systemic lupus erythematosus in a subject in need thereof, comprising the administration of a therapeutically effective amount of a nucleic acid which encodes human DEF6 protein and a nucleic acid which encodes human SWAP-70 protein, wherein the administration of the nucleic acid which encodes human DEF6 protein and the nucleic acid which encodes human SWAP-70 protein abolishes or decreases pathogenic age-associated B cells, and wherein the pathogenic age-associated B cells are CD11c+ and secrete anti-dsDNA IgG.