Patent ID: 11925643
Assignee: BAR ILAN UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A compound represented by the formula (I):, or a stereoisomer, enantiomer or pharmaceutically acceptable salt thereof, wherein
R1 is aryl or heteroaryl; and
R2 is alkyl, alkynyl, or cycloalkyl, wherein the alkyl is a lower alkyl having 3 to 10 carbon atoms; the alkynyl is a medium size alkynyl having 2 to 8 carbon atoms; the cycloalkyl is a saturated, all-carbon monocyclic or polycyclic (fused ring) group, having 3 to 8 carbon atoms; the aryl is an all-carbon, non-saturated monocyclic or (fused-ring group having 6 to 10 carbon atoms; and the heteroaryl is a non-saturated monocyclic or polycyclic (fused ring) group having in the ring(s) one or more heteroatoms selected from nitrogen, oxygen and sulfur;
wherein the alkyl, alkynyl, cycloalkyl and aryl are optionally substituted by one or more groups selected from the group consisting of: S, N, alkyl, mono-, di- or tri-haloalkyl, —O—(C1-C8)alkyl, —O—(C3-C8)cycloalkyl, hydroxyalkyl, (C3-C8)cycloalkyl, alkenyl, aryl, heterocycloalkyl, halo, OH, O-aryl, —SH, —S—(C1-C8)alkyl, —S—(C3-C8)cycloalkyl, —S-aryl, —O—S═O, —S(═O)2—R′, —CN, —NO2, aralkoxyl, alkylcarbamido, arylcarbamido, alkylamino, arylamino, dialkylamino, diarylamino, arylalkylamino, aminocarbonyl, alkylaminocarbonyl, arylaminocarbonyl, arylcarbonyloxy, carboxyl, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonylamido, alkylsulfinyl, arylsulfinyl, sulfonylamides, sulfones, —P(═O)(OR′)(OR″), —PR′R″, —C(═O)—R′, —C(═S)—R′, —C(═O)—O—R′, —C(═S)—O—R′, —OC(═O)—NR′R″, —OC(═S)—NR′R″, —OC(═S)—NR′R″ and —S(═O)2—NR′R″, where R′ and R″, each independently, is hydrogen, alkyl, alkenyl, cycloalkyl, aryl, heteroaryl (bonded through a ring carbon) or heterocycloalkyl (bonded through a ring carbon).