Patent ID: 11911136
Assignee: IMEC NEDERLAND
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A

Claim 12:
13. A method implemented by an electronic system or device for determining cardiac pulse transit time or pulse arrival time information of a subject using a primary cardiac pulse signal and an electronic audio signal, wherein the electronic audio signal comprises information representative of a human voice signal in a time-domain, the human voice signal comprising a vowel audio sound of a certain duration and a fundamental frequency (F0), and the method comprising:
receiving the electronic audio signal and the primary cardiac pulse signal, wherein the electronic audio signal and the primary cardiac pulse signal are synchronized time-domain signals;
generating a power spectral profile of a section of the electronic audio signal;
detecting the fundamental frequency (F0) in the generated power spectral profile;
filtering the received audio signal within a band around at least the detected fundamental frequency (F0) and thereby generating a denoised audio signal wherein filtering the received audio signal within the band includes within bands around one or more multiples of the detected fundamental frequency (F0) and to generate one or more denoised audio signals;
generating a time-domain intermediate signal that captures one or more of: a frequency, an amplitude, or a phase of the denoised audio signal; and
detecting at least one intermediate signal fiducial point within a human cardiac band in the intermediate signal;
detecting at least one primary cardiac pulse fiducial point within a human cardiac band in the primary cardiac pulse signal; and
generating an estimation of arterial blood pressure based on the pulse transit time or pulse arrival time information between the at least one detected primary cardiac pulse fiducial point and the at least one detected intermediate signal fiducial point.