Patent ID: 11896737
Assignee: GALDERMA HOLDING SA
Field: Medical technology (Instruments)
Classification: CPC A  C | IPC A  C

Claim 17:
18. An injectable gel product comprising a first, inner phase of a plurality of cross-linked glycosaminoglycan (GAG) gel particles embedded in a second, outer phase of a cross-linked GAG gel,
wherein the second, outer phase is in the form of particles,
wherein the gel of the first, inner phase has a Degree of Modification (MoD) of 0.15 or lower,
wherein the gel of the second, outer phase has a MoD that is lower than the MoD of the gel of the first, inner phase, and
wherein the MoD is the molar amount of bound cross-linking agent(s) relative to the total molar amount of repeating GAG disaccharide units;
wherein the inner phase, the outer phase, or both the inner phase and the outer phase are crosslinked via one or more polyfunctional cross-linking agent selected from 1,4-butanediol diglycidyl ether (BDDE), 1,2-ethanediol diglycidyl ether (EDDE) and diepoxyoctane.