Patent ID: 11872239
Assignee: SYNTHENA AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 1:
2. The composition of claim 1, wherein the spacer comprises any one of formulas (a)-(g):
a. #-NH—C2-12alkylene-§,
b. #-NH—C2-12alkylene-OP(OH)-§,
c. #-NH—C2-12alkylene-OP(O)(SH)-§,
d. #-NH—C2-12alkylene-OP(O)(OH)-§,
e. #-NH—C2-12alkylene-NH—C(O)-§,
f. #-NH—C2-12alkylene-NH—P(O)(OH)-§,
g. #-NH—C2-12alkylene-NH—P(O)(SH)-§,
wherein one or more —CH2-moieties in C2-12 alkylene are optionally replaced independently by —O—, —S—, —NH—, —C(O)—, —C(O)O—, an aryl, a heteroaryl, a cycloalkyl, a heterocycloalkyl, —OP(OH)O—, —OP(O)(SH)O—, —OP(O)(OH)O—, —NHP(O)(OH)O—, —NHP(O)(SH)O—, or —(O—CH2—CH2)k— with k being an integer of 1 to 8, and wherein one or more —CH2-moieties in C2-12 alkylene are independently of each other optionally substituted with one or more —COOH, —NH2, —OP(O)(OH)2 or —OH, and wherein the (#) symbol represents the point of covalent linkage to a lipid moiety and the (§) symbol represents the point of covalent linkage to the oligomeric compound.