Patent ID: 11874272
Assignee: FIRMENICH SA
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method,
wherein the method identifies compounds having the ability to prevent, treat, or reduce malodor development on body surfaces, the method comprising the steps of:
a. contacting a subject with a test compound;
b. collecting a sample comprising at least one malodor causing volatile compound directly from the headspace of the axilla of a subject, wherein the sample is an air sample, wherein the sample is collected using a sampling apparatus comprising a sampling cell and a sampling tube;
c. adsorbing the collected sample onto an adsorbent material; and
d. determining, in the adsorbed collected sample, the amount of at least one malodor causing volatile compound selected from the group consisting of: 3-methyl-2-hexenoic acid (3M2H), 3-hydroxy-3-methylhexanoic acid (HMHA), and 3-methyl-3-sulfanylhexan-1-ol (MSH),

wherein the determining step is performed by thermal desorption GC/MS, and
wherein the test compound prevents, treats, or reduces malodor development on body surfaces if the amount of the at least one malodor causing volatile compound is lower in the sample collected from the subject contacted with the test compound compared to the amount of the at least one malodor causing volatile compound in a sample collected from a non-treated subject.