Patent ID: 11970696
Assignee: LEIDOS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C  G

Claim 0:
1. A data storage system comprising:
a surface array including thereon multiple strands of immobilized double-stranded DNA oligomers, wherein a first end of each of the multiple strands is attached to the surface array and a second end of each of the multiple strands of immobilized double-stranded DNA oligomers is blunt such that both a forward and a reverse strand thereof are of equal lengths at the second end, and further wherein each of the multiple strands of immobilized double-stranded DNA oligomers includes a photocleavable optical linker at a first location of a forward strand of each of the multiple strands of immobilized double-stranded DNA oligomers;
an optical source for directing light at a first time to the surface array in a predetermined pattern, wherein when the light interacts with each photocleavable optical linker, a sticky end at the second end of each of the multiple strands of immobilized double-stranded DNA oligomers is exposed, while the first end of each of the multiple strands remains attached to the surface array;
multiple reagent wells storing data-encoded DNA cassettes, wherein each data-encoded DNA cassette includes a photocleavable optical linker at a first location of a forward strand of each of the data-encoded DNA cassettes;
means for introducing the data-encoded DNA cassettes to the surface array, wherein each of the data-encoded DNA cassettes is capable of being attached to an exposed sticky end,
wherein, the optical source directs light to the surface array containing at least some combinations of the data-encoded DNA cassettes attached to the immobilized double-stranded DNA oligomers, wherein the light interacts with each photocleavable optical linker of each of the data-encoded DNA cassettes to create a sticky end at an unattached end of each of the data-encoded DNA cassettes; and
further wherein additional data-encoded DNA cassettes from the multiple reagent wells are introduced to the surface array containing the combinations of the data-encoded DNA cassettes attached to the immobilized double-stranded DNA oligomers and at least some of the additional data-encoded DNA cassettes attach to the sticky end of at least some of the data-encoded DNA cassettes.