Patent ID: 11920258
Assignee: RULES-BASED MEDICINE INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 1:
2. The method of claim 1, wherein the glycosylation site of (i) comprises the motif NXS, NXT, or NXC, in which X represents any naturally-occurring amino acid residue except for proline;
the deamidation site of (ii) comprises the motif of NG, NS, NT, NN, NA, NH, ND, GNF, GNY, GNT, or GNG;
the isomerization site of (iii) comprises the motif of DT, DH, DS, DG, or DD;
the tripeptide of (vi) is HYF or HWH;
the motif that promotes aggregation of (vii) comprises the motif of FHW;
the polyspecificity site of (viii) comprises the motif GG, GGG, RR, VG, W, WV, WW, WWW, YY, or WXW, in which X represents any amino acid residue
the protease cleavage site of (ix) comprises the motif of DX, in which X is P, G, S, V, Y, F, Q, K, L, or D;
the integrin binding site of (x) comprises RGD, RYD, LDV, or KGD;
the lysine glycation site of (xi) comprises KE, EK, or ED;
the metal catalyzed fragmentation site of (xii) comprises the motif of HS, SH, KT, HXS, or SXH, in which X represents any amino acid residue;
the polyspecificity aggregation site of (xiii) comprises a motif of X1X2X3, wherein each of X1, X2, and X3 independently is selected from the group consisting of F, I, L, V, W and Y; or
the streptavidin binding motif of (xiv) comprises the motif HPQ, EPDW (SEQ ID NO: 117), PWXWL (SEQ ID NO: 118), in which X represents any amino acid residue, GDWVFI (SEQ ID NO: 119), or PWPWLG (SEQ ID NO: 120).