Patent ID: 11892453
Assignee: INBIOMOTION S.L.
Field: Pharmaceuticals (Chemistry)
Classification: CPC G  A  C | IPC A  C  G

Claim 0:
1. A method for typing a sample of a subject suffering from prostate cancer, and treating said subject to inhibit metastasis or recurrence and/or to avoid, inhibit, and/or treat bone degradation, comprising:
(i) quantifying the expression level, copy number, or amplification of the c-MAF gene in a prostate tumor sample;
(ii) typing said prostate tumor sample by comparing the quantified expression level, copy number, or amplification of c-MAF to a predetermined reference level of c-MAF expression;
(iii) determining that said typing indicates a risk of bone metastasis in said subject; and
(iv) administering a therapeutically effective amount of a therapy aiming to inhibit and/or treat bone metastasis selected from the group consisting of a c-MAF inhibitor, an mTor inhibitor, a Src kinase inhibitor, a COX-2 inhibitor, a CCR5 antagonist and/or Radium-223, and/or an agent capable of avoiding, inhibiting, and/or treating bone degradation to said subject.