Patent ID: 11897914
Assignee: HONGENE BIOTECH CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A compound of Formula (I):, or a pharmaceutically acceptable salt thereof,
wherein
R1 is hydrogen or a hydroxy protecting group;
R2 is hydrogen, a hydroxy protecting group, —C(═O)CH2CH2C(═O)R3, or —P(OR4)NR5R6;
alternatively, R1 and R2 are joined together to form a 6-10 membered heterocyclic ring;
RHet is optionally substituted 5-10 membered heteroaryl or optionally substituted 5-10 membered heterocyclyl;
R3 is hydroxy, —OR7 or —NR8R9;
each of R4, R5 and R6 is independently H, unsubstituted C1-C6 alkyl, or substituted C1-C6 alkyl;
R7 is unsubstituted C1-C6 alkyl, substituted C1-C6 alkyl, or a hydroxy protecting group;
each of R8 and R9 is independently H, unsubstituted or substituted C1-6 alkyl, or an amino protecting group; and
B is a natural nucleobase, a modified natural nucleobase, or an unnatural nucleobase.