Patent ID: 11970524
Assignee: BOSTON MEDICAL CENTER CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A recombinant Roundabout Receptor 2 (ROBO2) protein comprising (i) a portion of ROBO2 extracellular domain, and (ii) an immunoglobulin domain, wherein said portion of ROBO2 extracellular domain comprises:
a) a ROBO2 first immunoglobulin-like domain (Ig1) of SEQ ID NO:9,
b) an inter domain linker between first and second immunoglobulin-like domains (Ig1-Ig2 inter-domain linker) of SEQ ID NO:10,
c) a second immunoglobulin-like domain (Ig2) of SEQ ID NO:11, and
d) an inter-domain linker between second and third immunoglobulin-like domains (Ig2-Ig3 inter-domain linker) of SEQ ID NO:12,
and wherein the recombinant ROBO2 protein is devoid of the three fibronectin type III (FNIII) repeats of the ROBO2 extracellular domain.