Patent ID: 11866496
Assignee: GENENTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 6:
7. The immunoconjugate of claim 1, wherein the cytotoxic agent is a drug moiety,
wherein the anti-CD79b antibody comprises a heavy chain and a light chain, and
wherein the anti-CD79b antibody comprises an engineered cysteine at one or more positions selected from the group consisting of 15, 43, 110, 144, 168, and 205 of the light chain according to Kabat numbering convention, and 41, 88, 115, 118, 120, 171, 172, 282, 375, and 400 of the heavy chain according to EU numbering convention.