Patent ID: 11952376
Assignee: PLIANT THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 133:
134. The compound of claim 125, wherein the compound is of formula (II-A-2):, , or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof,
wherein:
R2 is oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, octahydrobenzofuran-4-yl, octahydrobenzofuran-5-yl, octahydrobenzofuran-6-yl, or octahydrobenzofuran-7-yl, chroman-5-yl, chroman-6-yl, chroman-7-yl, chroman-8-yl, 2,3-dihydrobenzo[b][1,4]dioxin-5-yl, 2,3-dihydrobenzo[b][1,4]dioxin-6-yl, 2,3-dihydrobenzo[b][1,4]dioxin-7-yl, or 2,3-dihydrobenzo[b][1,4]dioxin-8-yl:
wherein the oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, octahydrobenzofuran-4-yl, octahydrobenzofuran-5-yl, octahydrobenzofuran-6-yl, or octahydrobenzofuran-7-yl, chroman-5-yl, chroman-6-yl, chroman-7-yl, chroman-8-yl, 2,3-dihydrobenzo[b][1,4]dioxin-5-yl, 2,3-dihydrobenzo[b][1,4]dioxin-6-yl, 2,3-dihydrobenzo[b][1,4]dioxin-7-yl, or 2,3-dihydrobenzo[b][1,4]dioxin-8-yl is optionally substituted by 1, 2, 3, or 4 independently selected R2e substituents.