Patent ID: 11857560
Assignee: EMORY UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 10:
11. A method for the treatment of a viral infection in a patient in need thereof, wherein the method comprises administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising at least one pharmaceutically acceptable excipient and a compound of Formula Im:, or a pharmaceutically acceptable salt or tautomer thereof,
wherein:
R1 is:, R2 is alkyl or cycloalkyl;
R3 is aryl, wherein the aryl is optionally substituted with one or more independently selected R9 substituents;
each R4 is independently C1-22 alkyl, OC1-22 alkyl, or cycloalkyl;
R5 is C1-22 alkyl, C2-22 alkenyl, C2-22 alkynyl, OC1-22 alkyl, aryl, heteroaryl, or lipid, wherein the aryl or heteroaryl is optionally substituted with one or more independently selected R9 substituents; and
each R9 is independently D, halogen, CN, NO2, alkyl, C(O)H, C(O)alkyl, C(O)NH2, C(O)OH, NH2, NH(alkyl), N(alkyl)2, OH, O(alkyl), SH, S(alkyl), S(O)alkyl, S(O)2alkyl, S(O)2aryl, carbocyclyl, heterocyclyl, or aryl.