Patent ID: 11931414
Assignee: SEAGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 6:
7. The Ligand Drug Conjugate compound of claim 1, wherein —IN-TN has the structure of:, wherein
Xb when present is independently selected from the group consisting of halogen, —OH, optionally substituted C1-C4 alkoxy, optionally substituted C1-C4 alkyl, and optionally substituted —NH2, and subscript n is 0, 1, or 2; and
the wavy line indicates the site of covalent attachment to DA, or
wherein —IN-TN has the structure of:, wherein
Xb if present is selected from the group consisting of optionally substituted —OH, optionally substituted NH2, and halogen, and subscript n is 0, 1, or 2, provided that when subscript n is 2 one of Xb is optionally substituted —OH, optionally substituted —NH2, or halogen and the other is halogen; and
the wavy line indicates the site of covalent attachment to DA.