Patent ID: 11887710
Assignee: NEO7LOGIX, LLC
Field: Medical technology (Instruments)
Classification: CPC G  Y | IPC G

Claim 12:
13. A personalized peptide vaccine composition, comprising:
a plurality of peptide sequences encoding self-antigens and neo-antigens for a CD4+/CD8+ Natural Killer (NK) cell modulation specific to a patient's profile, and able to elicit an effective therapeutic response against a patient disease;
wherein a patient has been diagnosed with, or is genetically predisposed to, a disease comprising: a cancer, an autoimmune disease, a neurodegenerative disease, or a pathogen related infectious disease;
wherein the plurality of peptide sequences comprises about 5 to about 20 peptide sequences computed to be the most therapeutically effective for treating the patient; and
wherein the individualized therapeutic peptides or peptide vaccine composition is produced by:
receiving a data input, by a cloud-based system, of a patient data comprising one or more of: a patient transcriptomics data, and a patient urine proteomics data;
computing a precision data output, by the cloud-based system, of a vaccine composition comprising a plurality of therapeutic peptide sequences encoding peptides, self-antigens or neo-antigens specific to a patient's profile, and able to elicit an effective therapeutic response against a patient disease;
computing a CRISPR prime editing and an intracellular multi-core processing on the vaccine composition to produce a DNA-RNA and epigenetic modulation plurality of immunopeptide sequences; and
conducting an immunopeptide synthesis and manufacturing of the vaccine composition.