Patent ID: 11970480
Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC C

Claim 9:
10. The compound or salt according to claim 1 having the structure of Formula (I-N-B′), , wherein
R3 and R5 are each independently —CON(Rd)(Rf), or one of R3 and R5 
is —CON(Rd)(Rf), and the other of R3 and R5 is H, COOH or —CO2(Rc);
Rc is C1-C4alkyl;
RB1 and RB2 are each independently —CH2—;
B is -halo(C1-C5alkyl), unsubstituted —C1-C5allkyl, or unsubstituted —C2-C5alkenyl-;
RA2 and RA1 are each independently H, halogen, hydroxyl, —O—P(O)(OH)2,
—O—P(O)(RIRII)2, optionally substituted (C1-C6alkyl), or optionally substituted (C1-C6alkyl)oxy-,
wherein C1-C6alkyl of said optionally substituted (C1-C6alkyl), or optionally substituted (C1-C6alkyl)oxy- is optionally substituted with 1-4 substituents each independently selected from the group consisting of hydroxyl, —O—P(O)(OH)2,
—O—P(O)(RIRII)2, C1-C4alkoxyl, —N(Re)(Rf), —CO2(Rf), optionally substituted phenyl, and optionally substituted 5-6 membered heterocycloalkyl; wherein said optionally substituted phenyl, or 5-6 membered heterocycloalkyl is optionally substituted by 1-4 substituents each independently selected from halogen, hydroxy, —O—P(O)(OH)2, —O—P(O)(RIRII)2, amino, (C1-C6alkyl)amino-, (C1-C6alkyl)(C1-C6alkyl)amino-, halo(C1-C6alkyl), hydroxy-(C1-C4alkyl)-, —(C1-C4alkyl)-O—P(O)(OH)2, —(C1-C4alkyl)—O—P(O)(RIRII)2, halo(C1-C4alkoxy)-, C1-C4alkoxy-, hydroxy-(C2-C4alkoxy)-, —(C2-C4alkoxy)-O—P(O)(OH)2, —(C2-C4alkoxy)—O—P(O)(1002, —(C1-C6alkyl)—NH2, —C1-C4alkyl-(C1-C4alkoxyl) and C1-C4alkoxy-(C1-C4alkoxy)-;

each Rd is independently H or C1-C4alkyl;
Re is selected from H, (C1-C4alkyl), —CO(C1-C4alkyl), —OCO(C1-C4alkyl), —(C1-C4alkyl)—NH2, —(C1-C4alkyl) C1-C4alkoxy, or —CO2(C1-C4alkyl), each occurrence of Rf is H or (C1-C4alkyl);
R4 and R6 are H;
R14 is C1-C4alkyl;
RC1 is H or C1-C4alkyl;
RC2 is C1-C4alkyl;
R15 is H or C1-C4alkyl;
R16 is H or C1-C4alkyl;
R17 is H or C1-C4alkyl; and
each occurrence of RI and RII are independently (C1-C6alkyl)oxy-, or a tautomer thereof.