Patent ID: 11918832
Assignee: INSIGHTEC LTD.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A system for temporarily disrupting a patient's blood-brain barrier (BBB), the system comprising:
an ultrasound transducer; and
a controller configured to:
(a) store a threshold value of a cumulative acoustic response dose associated with at least one of a target BBB region or its surrounding regions, the threshold value corresponding to a maximum clinically tolerable cumulative amount of microbubble cavitation;
(b) cause the transducer to transmit at least one ultrasound pulse;
(c) acquire the cumulative acoustic response dose associated with the at least one of the target BBB region or its surrounding regions;
(d) compare the cumulative acoustic response dose acquired in step (c) with the stored threshold value; and
(e) suspend ultrasound sonication when the cumulative acoustic response dose acquired in step (c) exceeds the stored threshold value.