Patent ID: 11896700
Assignee: L'OREAL
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 6:
7. The process according to claim 4, wherein the compound(s) of formula (I), (II), (I′), or (II′) are chosen from: 2,2′-[(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diylimino)]diethanol; 3,3′-[(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diylimino)]dipropan-1-ol; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(dimethylamino)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(dimethylamino)propyl]pyrazolo-[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)-bis{N2-[2-(pyrrolidin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(pyrrolidin-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(piperidin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(piperidin-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(morpholin-4-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(4-methylpiperazin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(4-methylpiperazin-1-yl)propyl]pyrazolo-[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(1H-imidazol-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; 2,2′-[(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diyloxy)]diethanol; 3,3′-[(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diyloxy)]dipropan-1-ol; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(dimethylamino)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(dimethylamino)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(pyrrolidin-1-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(pyrrolidin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(piperidin-1-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(piperidin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(morpholin-4-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(morpholin-4-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(4-methylpiperazin-1-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(4-methylpiperazin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(1H-imidazol-1-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(1H-imidazol-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(2-methoxypyrazolo[1,5-a]pyridin-3-amine); N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(2-ethoxypyrazolo[1,5-a]pyridin-3-amine); N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(2-propoxypyrazolo[1,5-a]pyridin-3-amine); N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[2-(propan-2-yloxy)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(2-ethoxyethoxy)ethoxy]-6,7-dimethylpyrazolo[1,5-a]pyridin-3-amine}; 2-{2-[(3-([3-amino-6-({2-[2-(2-hydroxyethoxy)ethoxy]pyrazolo[1,5-a]pyridin-3-yl}amino)-5-imino-5,6-dihydropyridin-2(1H)-ylidene]amino}pyrazolo[1,5-a]pyridin-2-yl)oxy]ethoxy}ethanol; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(propan-2-yloxy)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(2-tert-butoxypyrazolo[1,5-a]pyridin-3-amine); N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{N2,N2-dimethylpyrazolo[-1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{N2,N2-diethylpyrazolo[1,5-a]pyridine-2,3-diamine}; 2,2′,2″,2″-[(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diylnitrilo)]tetraethanol; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[2-(pyrrolidin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[2-(piperidin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[2-(morpholin-4-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[2-(4-methylpiperazin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; 1,1′-[(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diyl)]dipyrrolidin-3-ol; 1,1′-[(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis(nitrilopyrazolo[1,5-a]pyridine-3,2-diyl)]dipyrrolidine-3,4-diol; 2,2′-{(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[nitrilo(6,7-dimethylpyrazolo[1,5-a]pyridine-3,2-diyl)imino]}diethanol; 3,3′-{(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis[nitrilo(6,7-dimethylpyrazolo-[1,5-a]pyridine-3,2-diyl)imino]}dipropan-1-ol; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{N2-[2-(dimethylamino)ethyl]-6,7-dimethylpyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{N2-[3-(dimethylamino)propyl]-6,7-dimethylpyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-N2-[2-(pyrrolidin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-N2-[3-(pyrrolidin-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[2-(piperidin-1-yl)ethyl]pyrazolo-[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[3-(piperidin-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[2-(morpholin-4-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[2-(4-methylpiperazin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)diylidene)bis{6,7-dimethyl-N2-[3-(4-methylpiperazin-1-yl)propyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[2-(1H-imidazol-1-yl)ethyl]-6,7-dimethylpyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(1H-imidazol-1-yl)propyl]-6,7-dimethylpyrazolo[1,5-a]pyridine-2,3-diamine}; 2,2′-{(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[nitrilo-(6,7-dimethylpyrazolo-[1,5-a]pyridine-3,2-diyl)oxy]}diethanol; 3,3′-{(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[nitrilo(6,7-dimethylpyrazolo-[1,5-a]pyridine-3,2-diyl)oxy]}dipropan-1-ol; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(dimethylamino)ethoxy]-6,7-dimethylpyrazolo[1,5-a]pyridin-3-amine; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2-[3-(dimethylamino)propyl]-6,7-dimethyl-pyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-N2-[2-(pyrrolidin-1-yl)ethyl]pyrazolo[1,5-a]pyridine-2,3-diamine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[3-(pyrrolidin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[2-(piperidin-1-yl)ethoxy]pyrazolo-[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[3-(piperidin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[2-(morpholin-4-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[3-(morpholin-4-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[2-(4-methyl-piperazin-1-yl)ethoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-[3-(4-methylpiperazin-1-yl)propoxy]pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[2-(1H-imidazol-1-yl)ethoxy]-6,7-dimethylpyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-[3-(1H-imidazol-1-yl)propoxy]-6,7-dimethyl-pyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-methoxy-6,7-dimethylpyrazolo[1,5-a]pyridin-3-amine}; N2-(2-ethoxy-6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-6-[(2-ethoxy-6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)imino]-3-imino-3,6-dihydropyridine-2,5-diamine; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{6,7-dimethyl-2-propoxypyrazolo[1,5-a]pyridin-3-amine}; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[6,7-dimethyl-2-(propan-2-yloxy)-pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{2-tert-butoxy-6,7-dimethylpyrazolo[1,5-a]pyridin-3-amine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2,N2,6,7-tetramethylpyrazolo[1,5-a]pyridine-2,3-diamine}; N3,N3′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis{N2,N2-diethyl-6,7-dimethylpyrazolo[1,5-a]pyridine-2,3-diamine}; 2,2′,2″,2″-{(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[nitrilo(6,7-dimethyl-pyrazolo[1,5-a]pyridine-3,2-diyl)nitrilo]}tetraethanol; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[6,7-dimethyl-2-(pyrrolidin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[6,7-dimethyl-2-(piperidin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[6,7-dimethyl-2-(morpholin-4-yl)pyrazolo[1,5-a]pyridin-3-amine]; N,N′-(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[6,7-dimethyl-2-(4-methylpiperazin-1-yl)pyrazolo[1,5-a]pyridin-3-amine]; 1,1′-{(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[nitrilo(6,7-dimethylpyrazolo[1,5-a]pyridine-3,2-diyl)]}dipyrrolidin-3-ol; 1,1′-{(5-amino-3-iminopyridine-2,6(1H,3H)-diylidene)bis[nitrilo(6,7-dimethylpyrazolo[1,5-a]pyridine-3,2-diyl)]}dipyrrolidine-3,4-diol or leuco forms thereof, optical isomers, geometrical isomers, tautomers, solvates or addition salts thereof.