Patent ID: 11969426
Assignee: GENENTECH, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 7:
8. The process according to claim 3, wherein the process is performed with process parameters as follows:
feed solution of 20 to 25% (w/w) ipatasertib•HCl•EtOAc 75 to 80% (w/w) water;
(ii) atomizer of a rotary wheel type atomizer or two-fluid nozzle;
(iii) atomizer speed of 10000 to 28000 RPM in case of rotary wheel atomizer;
(iv) atomizing gas pressure of 2.2 to 2.6 bar in case of two-fluid nozzle;
(v) drying gas inlet temperature of 160 to 180° C.;
(vi) drying gas outlet temperature of 90 to 120° C.;
(vii) drying gas (nitrogen) of 450 kg/h, particularly in closed cycle mode; and
(viii) condensing temperature (step (h)) of 5 to 9° C.