Patent ID: 11952435
Assignee: NUTRITION & BIOSCIENCES USA 4, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  D | IPC A  C  D

Claim 0:
1. A method of producing insoluble alpha-glucan particles, said method comprising:
(a) providing insoluble alpha-glucan as produced in an enzymatic reaction comprising at least water, sucrose and a glucosyltransferase enzyme that synthesizes the insoluble alpha-glucan, wherein the insoluble alpha-glucan has a weight-average degree of polymerization (DPw) of at least about 200 and at least 50% of the glycosidic linkages of the insoluble alpha-glucan are alpha-1,3 glycosidic linkages; and
(b) hydrolyzing the insoluble alpha-glucan to insoluble alpha-glucan particles, wherein said hydrolyzing is performed under aqueous conditions at a pH of 2.0 or less;
wherein the insoluble alpha-glucan particles produced in step (b) have a degree of crystallinity of at least about 0.65 and a DPw of at least 15, and at least 50% of the glycosidic linkages of the insoluble alpha-glucan particles are alpha-1,3 glycosidic linkages.