Patent ID: 11944682
Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Field: Measurement (Instruments)
Classification: CPC A  C  G | IPC A  C  G

Claim 3:
4. The bioconjugate of claim 1, wherein the at least one AIEgen and linker is a moiety selected from the group consisting of:, or a pharmaceutically acceptable salt thereof, wherein
n is a whole number selected from 0-4;
each of R5 and R6 is independently selected from the group consisting of hydrogen, halide, cyano, nitro, —OR, —SR, —N(R)2, —(C═O)R, —(C═O)OR, —(C═O)N(R)2, —N(R)(C═O)R, —O(C═O)R, —N(R)(C═O)OR, —O(C═O)N(R)2, —SO2R, —SO2N(R)2, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, aralkyl, heterocycloalkyl, heteroaryl, and R8;
R8 represents a moiety having the structure:, wherein R9 for each instance is independently selected from the group consisting of hydrogen, halide, cyano, nitro, —OR, —SR, —N(R)2, —(C═O)R, —(C═O)OR, —(C═O)N(R)2, —N(R)(C═O)R, —O(C═O)R, —N(R)(C═O)OR, —O(C═O)N(R)2, —SO2R, —SO2N(R)2, alkyl, cycloalkyl, alkenyl, alkynyl, optionally substituted aryl, optionally substituted aralkyl, heterocycloalkyl, and optionally substituted heteroaryl;
R for each occurrence is independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, optionally substituted aryl, optionally substituted aralkyl, heterocycloalkyl, and optionally substituted heteroaryl; or two instances of R taken together with the atom or atoms to which they are covalently bonded form a 3-7 membered cycloalkyl or 3-7 membered heterocycloalkyl; and
Z for each occurrence is independently a pharmaceutically acceptable anion, wherein represents the site of covalent attachment to the bacteriophage.