Patent ID: 11911533
Assignee: POLYNOVO BIOMATERIALS PTY LIMITED
Field: Medical technology (Instruments)
Classification: CPC A  B  C | IPC A  B  C

Claim 0:
1. A tissue repair laminate comprising:
(a) two or more biodegradable polyurethane foam layers; and
(b) one or more structural layers;
wherein the one or more structural layers each have a thickness in the range of from about 50 μm to about 500 μm, and are positioned between said foam layers;
wherein the one or more structural layers consist essentially of biodegradable thermoplastic polyurethane and one or more apertures;
wherein said foam layers comprise a pore structure configured for cellular infiltration, and the foam of said foam layers is a non-reticulated foam;
wherein said tissue repair laminate shrinks due to formation of tissue less than 20% in any one surface area after 20 days under in vivo conditions following implantation of the tissue repair laminate;
and wherein the structural layer polyurethane is derived from components including
one or more chain extenders represented by formula (1) or formula (2), wherein R1, R2 and R3 are independently selected from optionally substituted C1-20 alkylene and optionally substituted C2-20 alkenylene;
one or more aliphatic polyester polyols; and
one or more aliphatic diisocyanates.