Patent ID: 11879900
Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
Field: Measurement (Instruments)
Classification: CPC G  A  H | IPC A  G  H

Claim 0:
1. A method for determining the amount of teriflunomide in a sample by mass spectrometry, said method comprising:
a. adding an internal standard to the sample;
b. purifying the sample by high turbulence liquid chromatography (HTLC);
c. ionizing the sample to produce one or more teriflunomide ions detectable by mass spectrometry;
d. determining the amount of the one or more teriflunomide ions by mass spectrometry; and
e. using the amount of the one or more ions determined in step (d) to determine the amount of teriflunomide in the sample; and
f. confirming the identity of teriflunomide by detecting a qualifier ion with m/z of 142.2±0.50.