Patent ID: 11898175
Assignee: GENZYME CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 7:
8. The method of claim 1, wherein
(i) the first two or more doses are escalating doses and are administered at a successively increasing amount,
(ii) the doses after the escalating doses are maintenance doses and are administered in the same amount as or less than the last escalating dose,
(iii) the first dose is in the amount of 0.1 mg/kg and the patient is a pediatric patient,
(iv) the first dose is in the amount of 0.1 mg/kg and the patient is an adult patient,
(v) the highest maintenance dose is in the amount of 0.3 mg/kg to 3 mg/kg,
(vi) the highest maintenance dose is in the amount of 1 mg/kg,
(vii) the highest maintenance dose is in the amount of 2 mg/kg,
(viii) the highest maintenance dose is in the amount of 3 mg/kg,
(ix) the highest maintenance dose is the highest dose tolerated by the patient, and/or
(x) the escalating doses are administered in the order of 0.1 mg/kg, 0.3 mg/kg, 0.3 mg/kg, 0.6 mg/kg, 0.6 mg/kg, 1.0 mg/kg, 2.0 mg/kg, and 3.0 mg/kg.