Patent ID: 11896488
Assignee: MARQUETTE UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method of preparing a scaffold for use in bone tissue engineering, the method comprising:
obtaining a 3D model of a treatment area of a patient;
determining a degradability of the scaffold based upon the patient and treatment area;
selecting a first porosity of a skeleton and a first rate of biodegradation of the skeleton;
selecting a second porosity of a host component and a second rate of biodegradation of the host component to achieve the degradability;
digitally designing a skeleton to fit the treatment area;
manufacturing the skeleton with a material having the first porosity and first rate of biodegradation to form a three-dimensional shape defining a space; and
filling the space defined by the skeleton with the host component having the second porosity and the second rate of biodegradation, wherein the first porosity is smaller than the second porosity and the first rate of biodegradation is slower than the second rate of biodegradation.