Patent ID: 11932703
Assignee: CARIBOU BIOSCIENCES, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. An anti-human ROR1 antibody or an antigen-binding fragment thereof comprising VH having an amino acid sequence at least 90% identical to SEQ ID NO: 2 and VL having an amino acid sequence at least 90% identical to SEQ ID NO: 3, the antibody or antigen-binding fragment comprising complementarity determining regions (CDRs) in the VH and the VL, wherein a CDR1 of the VH comprises the sequence TYA, a CDR2 of the VH comprises SEO ID NO: 41, a CDR3 of the VH comprises SEO ID NO: 42, a CDR1 of the VL comprises SEQ ID NO: 43, a CDR2 of the VL comprises the sequence RAN, and a CDR3 of the VL comprises SEQ ID NO: 45.