Patent ID: 11931569
Assignee: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A method for treating a subject in need thereof, the method comprising:
selecting a treatment region within a central nervous system (CNS);
mounting, on an external surface of the subject, an electric field source that comprises one or both of (i) a plurality of electrodes and (ii) a magnetic field source configured to generate a changing magnetic field; and
applying a pulsed electric field with said electric field source to at least a portion of the CNS,
wherein the pulsed electric field has an electric field strength of less than 148 V/cm and a frequency of less than 75 Hz within the treatment region, being below a threshold for inducing electroporation in the treatment region,
wherein applying the pulsed electric field induces disruptive permeability of a blood brain barrier or a blood cerebrospinal fluid barrier in the treatment region.