Patent ID: 11896677
Assignee: HDT BIO CORP.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  B  Y | IPC A  B  C

Claim 0:
1. A composition, wherein the composition comprises:
nucleic acids, wherein the nucleic acids comprise a sequence encoding for a protein region;
lipid nanoparticles, wherein the lipid nanoparticles are characterized as having a z-average diameter particle size measurement of 20 nm to about 60 nm when measured using dynamic light scattering, and wherein the lipid nanoparticles comprise:
a surface comprising cationic lipids; and
a hydrophobic core that comprises liquid oil, wherein lipids present in the hydrophobic core are in liquid phase at 25 degrees Celsius,

wherein the nucleic acids are complexed to the cationic lipids to form nucleic acid-lipid nanoparticle complexes; and
an adjuvant for innate immune stimulation.