Patent ID: 11959838
Assignee: VENTANA MEDICAL SYSTEMS, INC.
Field: Measurement (Instruments)
Classification: CPC G  A  C | IPC A  G

Claim 0:
1. A method for preparing a representative sample for analysis, comprising:
a) obtaining a surgical resection tissue sample from a tumor of a subject, wherein the obtained surgical resection tissue sample is at least 1 cm in diameter at its widest point, and wherein the obtained surgical resection tissue sample is fixed; and wherein the obtained surgical resection tissue sample is not derived from a formalin-fixed paraffin-embedded sample; and
b) mechanically blending the obtained surgical resection tissue sample to provide the representative sample, wherein any heterogeneity of cells within the obtained surgical resection tissue sample is substantially homogeneously distributed within the representative sample, and wherein any aliquot removed from the representative sample comprises one or more populations of subclones at a proportion at which they existed within the obtained surgical resection tissue sample.