Patent ID: 11879159
Assignee: BEIJING ORIGINPOLY BIO-TEC CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 1:
2. The composition for early detection of high-grade cervical lesions and cervical cancer according to claim 1, characterized in that: the composition further includes the Taqman probe corresponding to methylated sites in FAM19A4 gene, the Taqman probe corresponding to methylated sites in JAM3 gene, the Taqman probe corresponding to methylated sites in PAX1 gene, and the Taqman probe corresponding to the internal reference gene GAPDH, wherein:
the sequence of the FAM19A4 gene probe is FAM-SEQ ID NO. 9-BHQ1;
the sequence of the JAM3 gene probe is ROX-SEQ ID NO. 10-BHQ2;
the sequence of the PAX1 gene probe is CY5-SEQ ID NO. 11-BHQ2; and
the sequence of the internal reference gene GAPDH probe is VIC-SEQ ID NO. 12-BHQ1.