Patent ID: 11919894
Assignee: MERCK SHARP & DOHME LLC
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 14:
15. The compound of claim 1 that is:
(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl ((5-methyl-1,3,4-thiadiazol-2-yl)methyl)(2-methyl-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-yl)carbamate;
N-((5-Methyl-1,3,4-thiadiazol-2-yl)methyl)-N-(2-methyl-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-yl)-S-phenylthiohydroxylamine;
N-((5-Methyl-1,3,4-thiadiazol-2-yl)methyl)-N-(2-methyl-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-yl)benzamide;
((((5-Methyl-1,3,4-thiadiazol-2-yl)methyl)(2-methyl-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-yl)carbamoyl)oxy)methyl benzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl hexanoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl propanoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl pyridine-4-carboxylate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl pyridine-2-carboxylate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl pyridine-3-carboxylate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 4-fluorobenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 3-fluorobenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 2-fluorobenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 2-methoxybenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 3-methoxybenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 4-methoxybenzoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 2-methylpropanoate;
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl cyclohexanecarboxylate; or
({(2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-yl)[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamoyl}oxy)methyl 2-ethylbutanoate;
or a pharmaceutically acceptable salt thereof.