Patent ID: 11939296
Assignee: THE UNIVERSITY OF SYDNEY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of treating a proliferative disease, the method comprising administering to a subject in need thereof an effective amount of a compound of formula (I):, wherein:
X is C3 alkenyl;
Y is, W is O;
R2 is H, alkyl or alkenyl;
Z is a heteroaryl group, which heteroaryl group is optionally substituted with a hydroxyl, a halo group or a heteroalkyl group;
R1 is phenyl, which is optionally substituted with a halo group or a heteroalkyl group;
Ar is phenyl, wherein R1 and X are para to each other around the phenyl of Ar,
or a pharmaceutically acceptable salt or prodrug thereof,
wherein the proliferative disease is a cancer selected from brain cancer, breast cancer, lung cancer, prostate cancer, ovarian cancer, uterine cancer, skin cancer, colon cancer and bladder cancer.