Patent ID: 11879150
Assignee: KABUSHIKI KAISHA YAKULT HONSHA
Field: Biotechnology (Chemistry)
Classification: CPC C  G | IPC C  G

Claim 0:
1. A selection method of regimens, for selecting between either a FOLFOX regimen or a FOLFIRI regimen for treating colorectal cancer, the method comprising:
measuring a gain in a copy number of a specific region on a human chromosome in a tumor tissue specimen of the colorectal cancer, wherein the specific region on the human chromosome is at least one region among 7p15.3, 7q34, 8q24.1, 8q24.2, 8q24.1-q24.2, 9q34.3, 13q12.2, 13q14.11, 13q22.1, 13q32.2-q32.3, and 13q34; and
selecting the FOLFIRI regimen and treating the patient having colorectal cancer with the FOLFIRI regimen when the copy number of at least one region among 7q34, 8q24.1, 8q24.2, 8q24.1-q24.2, 13q12.2, 13q14.11, 13q22.1, 13q32.2-q32.3, 13q34, 20q12, 20q13.13, 20q13.2, and 20q13.3 is gained; or
selecting the FOLFIRI regimen and treating the patient having colorectal cancer with the FOLFIRI regimen when the copy number of the 9q34.3 region is not gained; or
selecting the FOLFIRI regimen and treating the patient having colorectal cancer with the FOLFIRI regimen when the copy number of the 7p15.3 region is not gained; or
selecting the FOLFOX regimen and treating the patient having colorectal cancer with the FOLFOX regimen when the copy number of the 7p15.3 region is gained and the copy number of the 8q24.1 region is not gained.