Patent ID: 11939385
Assignee: ALX ONCOLOGY INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 5:
6. The activatable antibody of claim 1, wherein the ABD specifically binds to EGFR, CTLA-4, PD-1, CD-71, PD-L1, HER2, CD3, a-4 integrin, a-V integrin, a-4-b-1 integrin, a-4-b-7 integrin, AGR2, Anti-Lewis_Y, Apelin J receptor, APRIL, B7-H3, B7-H4, BCMA, BTLA, C5 complement, C-242, CA9, CA19-9, Carbonic anhydrase 9, CD2, CD3, CD6, CD9, CD11a, CD19, CD20, IL27, IL27R, IL29, IL31, IL31R, Insulin Receptor, Jagged-1, Jagged-2, KIR, LAG-3, LIF-R, Lewis X, LIGHT, LRP4, LRRC26, CD22, CD24, CD25, CD27, CD28, CD30, CD40, CD40L, CD41, CD44, CD44v6, CD47, CD51, CD52, CD56, CD64, CD70, CD71, CD74, CD80, CD81, CD86, CD95, CD117, MCSP, Mesothelin, MRP4, MUC1, Mucin-16, Na/K ATPase, Neutrophil elastase, NGF, Nicastrin, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NOV, OSM-R, CD125, CD132, CD133, CD137, CD138, CD166, CD172A, CD248, CDH6, CEACM5, CEACAM6, CLAUDIN-3, CLAUDIN-4, cMet, Collagen, Cripto, CSFR, CSFR-1, CTLA-4, CTFG, CXCL10, CXCL13, CXCR1, CXCR2, OX-40L, OX-40R, PAR2, PDGF-AA, PDGF-BB, PDGFRa, PDGFRb, PD-1, PD-L1, PD-L2, Phospahtidyl-serine, P1GF, PSCA, PSMA, RAAG12, CXCR4, CYR61, DL44, DLK1, DLL4, DPP-4, DSG1, EGFR, EGFRVIII, Endothelin b receptor (ETBR), ENPP3, EPCAM, EPHA2, EPHB2, ERBB3, F protein of RSV, FAP, FGF-2, FGF-8, FGFR-1, FGFR-2, FGFR-3, FGFR-4, Folate receptor, RAGE, SLC44A4, TNFa, STEAP1, STEAP2, TAG-72, TAPA1, TGFb, TIGIT, TIM3, TLR2, TLR4, TLR6, TLR7, TLR8, GAL3STI, G-CSF, G-CSFR, GD2, GITR, GLUT1, GLUT4, GM-CSF, GM-CSFR, GPIIb/IIIa receptor, Gp130, GPNIVIB, GRP78, HER-2/neu, HGF, hGH, HVEM, Hyaluronidase, ICOS, INFa, INFb, INFg, IgE, TLR9, TMEM31, Sphingosine 1, Phosphate, TNFR, TNFRS12A, TRAIL-R1, TRAIL-R2, Transferrin, Transferrin Receptor, TRK-A, TRK B, uPAR, VCAM-1, VEGF, VEGF-A, IgE Receptor, IGF, IGF1R, IL1B, IL1R, IL2, IL2R, IL4, IL4R, IL6, IL6R, IL11, IL12, IL12p40, IL12R, IL12Rbl, IL13, IL13R, IL15, IL17, IL18, IL21, IL23, IL23R, VEGF-B, VEGF-C, VEGF-D, VEGFR1, VEGFR2, VEGFR3, VISTA, WISP-1, WISP-2, or WISP-3.