Patent ID: 11884651
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C  H

Claim 5:
6. A method of making the 7-(4-((4-benzylidene-5-oxo-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)methyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound of claim 1, the method comprising:
stirring a solution of 4-benzylidene-2-phenyl-1H-imidazol-5(4H)-one and formaldehyde in ethanol to obtain a reaction mixture;
adding ciprofloxacin HCl and triethylamine to the reaction mixture and stirring with reflux;
cooling the reaction mixture at room temperature to obtain a solid; and
obtaining the 7-(4-((4-benzylidene-5-oxo-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)methyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound.