Patent ID: 11932628
Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of formula I:, wherein:
R1 is H, or C1-30 alkyl; wherein the C1-30 alkyl is optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkoxy, —NRa2, —NHC(═NH)NRa2, —C(═O)NRa2, —COORa, and —SRa;
R2 is H, C1-8 alkyl or -L2-A2; wherein the C1-8 alkyl is optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkoxy, —NRb2, —NHC(═NH)NRb2, —C(═O)NRb2, —COORb, and —SRb;
R3 is H, or C1-30 alkyl; wherein the C1-30 alkyl is optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkoxy, —NRc2, —NHC(═NH)NRc2, —C(═O)NRc2, —COORc, and —SRc;
R4 is H, C1-30 alkyl or -L4-A4; wherein the C1-30 alkyl is optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkoxy, —NRd2, —NHC(═NH)NRd2, —C(═O)NRd2, —COORd, and −SRd;
L2 is absent or C1-4 alkylene;
L4 is absent or C1-4 alkylene;
A2 is cycloalkyl, aryl, or heteroaryl; wherein the cycloalkyl, aryl, and heteroaryl are optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkyl, C1-6 alkoxy, C1-6 haloalkyl, C1-6 haloalkoxy, and phenyl;
A4 is cycloalkyl; wherein the cycloalkyl is optionally substituted with one or more groups selected from the group consisting of halo, hydroxy, nitro, cyano, C1-6 alkyl, C1-6 alkoxy, C1-6 haloalkyl, C1-6haloalkoxy, and phenyl;
each Ra is independently H or C1-6 alkyl;
each Rb is independently H or C1-6 alkyl;
each Rc is independently H or C1-6 alkyl; and
each Rd is independently H or C1-6 alkyl;
or a salt thereof.