Patent ID: 11939307
Assignee: INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 6:
7. The compound or the pharmaceutically acceptable salt thereof as claimed in claim 6, wherein R4 is, , wherein, n=1-3, R7 and R8 are H or alkyl or substituted alkyl, or R7 and R8 together with the nitrogen atom to which they are bonded form a cyclic group or substituted cyclic group, the substituent is selected from the group consisting of alkyl, alkylamino, dialkylamino and heterocyclic group, the cyclic group is three-, four-, five-, six- or seven-membered saturated or unsaturated cyclic group containing 1 or 2 nitrogen atoms, the three-membered cyclic group is selected from aziridinyl, and the four-membered cyclic group is selected from azetidinyl, the five-membered cyclic group is selected from the group consisting of pyrrolyl, pyrrolidinyl, imidazolyl and oxazolyl, and the six-membered cyclic group is selected from the group consisting of morpholinyl, piperazinyl, piperidinyl, pyridinyl, and pyrimidinyl, the seven-membered cyclic group is 1,4-diazepanyl;
or R4 is, wherein R12 is alkyl containing 1-4 carbon atoms;
R11 the nitrogen to which R11 is bound, the carbon to which R10 is bound, the carbon to which R9 is bound, and R9 together form a saturated five-, six-, or seven-membered heterocyclic ring or a saturated five-, six-, or seven-membered heterocyclic ring substituted by 1 or 2 substituents selected from the group consisting of alkyl containing 1 to 4 carbon atoms, alkylamino, and dialkylamino, R10 is H; or R11, the nitrogen to which R11 is bound, the carbon to which R10 is bound, and R10 together form a saturated five-, six-, or seven-membered heterocyclic ring or a saturated five-, six-, or seven-membered heterocyclic ring substituted by 1 or 2 substituents selected from the group consisting of alkyl containing 1 to 4 carbon atoms, alkylamino, and di-C1-C4 alkylamino, R9 is H;
or, R4 is a substituted alkyl, the substituent is selected from the group consisting of amino, alkylamino, dialkylamino, and four-, five-, or six-membered saturated heterocycles containing one or two nitrogens.