Patent ID: 11932881
Assignee: SHANDONG UNIVERSITY
Field: Biotechnology (Chemistry)
Classification: CPC C  Y | IPC C

Claim 0:
1. A mutant heparin skeleton synthase (NaGlcNAc-T) is obtained from a wild-type NaGlcNAc-T, wherein the mutant NaGlcNAc-T is selected from the group consisting of a mutant heparin skeleton synthase having C16L mutation and comprises the amino acid sequence of SEQ ID NO: 4, a mutant heparin skeleton synthase having N25P mutation and comprises the amino acid sequence of SEQ ID NO: 6, a mutant heparin skeleton synthase having I30L mutation and comprises the amino acid sequence of SEQ ID NO: 8, a mutant heparin skeleton synthase having I111S mutation and comprises the amino acid sequence of SEQ ID NO: 10, a mutant heparin skeleton synthase having S165K mutation and comprises the amino acid sequence of SEQ ID NO: 12, a mutant heparin skeleton synthase having S172A mutation and comprises the amino acid sequence of SEQ ID NO: 14.