Patent ID: 11903951
Assignee: M ET P PHARMA AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A nasal pharmaceutical composition in the form of a gel adapted for nasal administration, comprising a loaded porous excipient dispersed in a pharmaceutically acceptable vehicle, wherein:
the loaded porous excipient comprises mesoporous silica particles wherein active agent in an amorphous state is loaded onto surfaces of the mesoporous silica particles located inside pores of the mesoporous silica particles, wherein the composition comprises from about 0.5% to about 50% w/w of the mesoporous silica based on the weight of the composition, and
the vehicle comprises an oil or mixture of oils in an amount from about 50% to about 90% w/w of the composition,
the composition comprises a therapeutically effective amount of the active agent of from 10% w/w to 50% w/w based on the weight of the composition, in a volume suitable for nasal application, and
the composition has a viscosity of from about 2000 to about 6000 mPa·sec.