Patent ID: 11885792
Assignee: AXOGEN CORPORATION
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 0:
1. A method for conducting a bioassay of an acellular nerve graft, the method comprising:
affixing a dorsal root ganglia (DRG) to a first end of the acellular nerve graft to form a test construct;
culturing the test construct in a medium for a period of time to allow nerve outgrowth from the DRG into the acellular nerve graft;
performing an analysis of the test construct to determine an amount of outgrowing nerve structure based on at least one of: a length of one or more peripheral nerve structures, or an amount of a target protein, or an amount of mRNA for a target protein associated with the outgrowing nerve structure; and
determining a potency of the acellular nerve graft based at least in part on the determined amount of outgrowing nerve structure.