Patent ID: 11857522
Assignee: BEYONDSPRING PHARMACEUTICALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 10:
11. A method for treating cancer, comprising co-administering a compound of Formula (I):, Y1 is selected from hydroxyl, C1-4 alkylamino and acylamino having a C1-4 alkyl moiety thereof;
Y2, Y3 and Y4 are independently selected from hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, trifluoromethyl, hydroxyl and benzyloxy; and
Q1 is either, , where Q2 and Q3 are independently selected from hydrogen and C1-4 alkyl;
X is selected from cyano, carboxyl or a derivative thereof, 5-tetrazolyl and alkylsulfonylcarbamyl having a C1-6 alkyl moiety thereof; and
n is 0 or an integer selected from 1, 2, 3, 4, 5 and 6, and a pharmaceutically acceptable salt thereof;
one or more immune checkpoint inhibitor; and
plinabulin to a subject in need thereof,
wherein the one or more immune checkpoint inhibitor is an inhibitor of PD-1, PD-L1, PD-L2, PD-L3, PD-L4 or CTLA-4.