Patent ID: 11967090
Assignee: ABBERIOR INSTRUMENTS GMBH
Field: Optics (Instruments)
Classification: CPC G | IPC G

Claim 19:
20. A microscope comprising
an objective,
a sample holder for positioning a sample relative to the objective, and
a device for detecting movements of the sample with respect to the objective, wherein the device comprises
an image sensor including an array of pixels, onto which the sample is imaged by means of the objective, the image sensor being configured for recording images of the sample in that light coming from the sample is registered at the pixels of the image sensor,

a selection module configured
to automatically determine temporal variations of intensities of light coming from the sample and registered at the individual pixels of the image sensor during a set-up period in that a temporal course of the intensity of the light registered at each respective individual pixel of the image sensor over the set-up period such that each pixel of the image sensor is analyzed separately, and
to automatically use the temporal variation of each of the pixels of the image sensor as a criterion in selecting a subset of not more than 90% of the pixels of the image sensor, and

a comparison module configured to compare parts of the images which each correspond to the subset of the pixels of the image sensor with parts of at least one reference image which also correspond to the subset of the pixels of the image sensor to detect undesired movements of the sample with respect to the objective.