Patent ID: 11911536
Assignee: SOUTHEAST UNIVERSITY
Field: Other special machines (Mechanical engineering)
Classification: CPC A  B | IPC A  B

Claim 1:
2. The method for molding a self-supporting silk fibroin catheter stent according to claim 1, wherein the specific steps of casting the solution in Step b comprises:
(1) weighing natural mulberry silk and adding to a NaCO3 solution with a concentration of 0.5±0.01% (g/ml), heating to 95-100° C., heating for 30-40 min starting from boiling, washing with ddH2O to remove the dissolved gum, and repeating the above steps 2-3 times to obtain silk fibroin, which is air dried for later use;
(2) weighing the silk fibroin in Step (1) and dissolving in a ternary solution of CaCl2/EtOH/H2O=1:2:8, where the ternary solution is prepared by dissolving anhydrous CaCl2 in ddH2O, and then adding absolute ethanol, slowly adding silk fibroin into the ternary solution in batches and stirring in a magnetic stirrer with heating at 72-75° C., and further stirring for 20-30 min after silk fibroin is completely dissolved to obtain a silk fibroin solution; and
(3) transferring the silk fibroin solution of Step (2) to a dialysis bag and dialyzing against ddH2O for 3-4 days, and then taking out, placing in a container and concentrating to 5-10% on an ultra-clean workbench, for later use.