Patent ID: 11858934
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound having the formula I:, or a pharmaceutically acceptable salt or stereoisomer thereof,
wherein:
R1 is NH(alkyl), NH(alkylenearyl), NH(alkyleneheteroaryl), NH(cycloalkyl), NH(aryl), NH(heteroaryl), O(alkyl), O(aryl), O(heteroaryl), aryl, or heteroaryl, wherein any alkyl, aryl of alkylenearyl, heteroaryl of alkyleneheteroaryl, cycloalkyl, aryl, or heteroaryl is optionally substituted with one, two, or three substituents independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 trihaloalkyl, C(O)NR4R5, NR4R5, OH, and OC1-C6 alkyl;
R2 is H, halogen, C1-C6 alkyl, C(O)NR4R5, C(O)OH, C(O)O(alkyl), C(O)O(cycloalkyl), C(O)O(heterocyclyl), C(O)O(aryl), C(O)O(heteroaryl), NH(alkyl), NH(cycloalkyl), NH(aryl), NH(heteroaryl), OH, OC1-C6 alkyl, O(aryl), or aryl, wherein any alkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl is optionally substituted with one, two, or three substituents independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 trihaloalkyl, C(O)NR4R5, NH2, OH, and OC1-C6 alkyl;
R3 is H, halogen, C1-C6 alkyl, C(O)NR4R5, C(O)OH, C(O)O(alkyl), C(O)O(cycloalkyl), C(O)O(heterocyclyl), C(O)O(aryl), C(O)O(heteroaryl), NH(alkyl), NH(cycloalkyl), NH(aryl), NH(heteroaryl), OH, OC1-C6 alkyl, O(aryl), or aryl, wherein any alkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl is optionally substituted with one, two, or three substituents independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 trihaloalkyl, C(O)NR4R5, NH2, OH, and OC1-C6 alkyl;
each R4 is independently H or C1-C6 alkyl, wherein each C1-C6 alkyl is optionally and independently substituted with one or more hydroxy substituents; and
each R5 is independently H or C1-C6 alkyl, wherein each C1-C6 alkyl is optionally and independently substituted with one or more hydroxy substituents; or
any R4 and R5, taken together with the nitrogen atom to which they are attached, independently forms a nitrogen-containing heterocyclyl, wherein each nitrogen-containing heterocyclyl is optionally and independently substituted with one, two, or three substituents independently selected from the group consisting of halogen, C1-C6 alkyl, C1-C6 trihaloalkyl, OH, and OC1-C6 alkyl.