Patent ID: 11873342
Assignee: LANOVA MEDICINES LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A monoclonal antibody or antigen-binding fragment thereof having binding specificity to a human chemokine (C—C motif) receptor 8 (CCR8) protein, wherein the antibody or fragment thereof each comprises a heavy chain variable region comprising heavy chain complementarity determining regions CDRH1, CDRH2, and CDRH3 and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2, and CDRL3, and wherein:
the CDRH1 comprises the amino acid sequence of SEQ ID NO: 35,
the CDRH2 comprises the amino acid sequence of SEQ ID NO: 36,
the CDRH3 comprises the amino acid sequence of SEQ ID NO: 37,
the CDRL1 comprises the amino acid sequence of SEQ ID NO: 25,
the CDRL2 comprises the amino acid sequence of SEQ ID NO: 26, and
the CDRL3 comprises the amino acid sequence of SEQ ID NO: 27.