Patent ID: 11865193
Assignee: IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A  B

Claim 0:
1. An equilibrium adsorption method for making a silica nanocarrier comprising superparamagnetic iron oxide nanoparticles and curcumin, comprising:
impregnating nanostructured pore surfaces of a platform of nanoporous structured silica with superparamagnetic iron oxide nanoparticles (SPIONs) to form an impregnated platform of structured silica,
calcining the impregnated platform of structured silica between 500 and 900° C. to form a calcined platform of structured silica, and
adsorbing a curcuminoid onto the calcined platform of structure silica and magnetic nanoparticles to form the silica nanocarrier, wherein the adsorbing includes mixing the calcined platform of structure silica and magnetic nanoparticles with an aqueous solution of the curcuminoid,
wherein the silica nanocarrier comprises
a platform of nanoporous structured silica selected from the group consisting of SiSBA-16, Q-10 silica, mesocellular foam, silicalite, mesosilicalite, SiKIT-6, ULPFDU-12, SiMCM-41, ZSM-5, USY, Mordenite, ZSM-11, ZSM-12, ZSM-22, ZSM-23, mesocarbon, graphene oxide and mixtures thereof,

wherein the superparamagnetic iron oxide nanoparticles (SPIONS) are present in an amount ranging from about 5 wt % to about 30 wt % based on total weight of the silica nanocarrier, and
wherein the curcuminoid is adsorbed on the surface of the nanoporous structured silica.