Patent ID: 11884724
Assignee: MERCK PATENT GMBH
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 4:
5. The isolated anti-PD-L1 antibody or antigen binding fragment of claim 4, wherein one or more of the heavy chain framework sequences is selected from:
(a) HC-FR1 is EVQLLESGGGLVQPGGSLRLSCAASGFTFS (SEQ ID NO:4);
(b) HC-FR2 is WVRQAPGKGLEWVS (SEQ ID NO:5);
(c) HC-FR3 is RFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR (SEQ ID NO:6); or
(d) HC-FR4 is WGQGTLVTVSS (SEQ ID NO:7).