Patent ID: 11878989
Assignee: SHANGHAI FOREFRONT PHARMA CO., LTD.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  Y | IPC C

Claim 6:
7. The method for preparing the L-erythro biopterin compound according to claim 5, wherein the steps of a cyclization reaction of the compound represented by formula (IVa-1) with, , and/or the salt of, , followed by a hydrolysis reaction are as follows: mix the compound represented by formula (IVa-1),, , and/or the salt of, , base and protonic solvent, and heat to 50-100° C. for reaction; after the reaction is completed, cool; a solid substance is precipitated; filter to obtain the compound represented by formula (I-1); add the compound represented by formula (I-1) into an alkaline solution; after the reaction is completed, add acid, and adjust the pH to 5-6; crystals are precipitated; filter and dry to obtain the L-erythro biopterin compound represented by formula (I);, R7 is —OH or —NH2.