Patent ID: 11939614
Assignee: NATIONAL RESEARCH COUNCIL OF CANADA
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. A process of altering the level of a cannabinoid compound in a cannabis plant, cannabis cell or cannabis tissue comprising introducing and expressing or over-expressing in the cannabis plant, cannabis cell or cannabis tissue a nucleic acid molecule selected from the group consisting of i) a nucleotide sequence as set forth in SEQ ID NO: 1 or 3 or a codon degenerate nucleotide sequence thereof; ii) a nucleotide sequence of 303 nucleotides that encodes a polypeptide with an amino acid sequence of SEQ ID NO: 2 or a conservatively substituted amino acid sequence thereof; and iii) a fragment of i) or ii) having a length of at least 300 base pairs; wherein the nucleic acid molecule encodes a polypeptide with polyketide cyclase activity, and selecting a cannabis plant, cannabis cell or cannabis tissue with altered levels of the cannabinoid compound, wherein the cannabis plant, cannabis cell or cannabis tissue contains the nucleic acid molecule.