Patent ID: 11918293
Assignee: HEARTFLOW, INC.
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 16:
17. A non-transitory computer-readable medium storing instructions that, when executed by a computer, cause the computer to perform operations for assessing organ or tissue transplantation, the operations comprising:
receiving one or more pre-transplantation medical images of a transplant recipient;
identifying voxels of the one or more pre-transplantation medical images of the transplant recipient that belong to a vasculature of the transplant recipient that provides circulation to a recipient organ or a recipient tissue intended to be replaced during a transplant;
constructing a patient-specific recipient anatomical model of the transplant recipient based on the identified voxels of the vasculature of the transplant recipient;
receiving one or more pre-transplantation medical images of a donor organ or a donor tissue of a transplant donor;
identifying voxels of the one or more pre-transplantation medical images of the transplant donor that belong to a vasculature of the transplant donor that provides circulation to the donor organ or the donor tissue intended to be replaced during the transplant;
constructing a patient-specific recipient anatomical model of the transplant donor based on the identified voxels of the vasculature of the transplant donor;
estimating blood flow through the patient-specific-recipient anatomical model of the transplant recipient to compute one or more blood flow characteristics of the transplant recipient;
automatically determining one or more connections between the recipient organ or the recipient tissue intended to be replaced during the transplant and the vasculature of the transplant recipient;
using the one or more connections, updating the patient-specific recipient anatomical model of the transplant recipient to construct a patient-specific virtual transplant model;
receiving one or more follow-up medical images of the transplant recipient during a transplantation procedure;
during the transplantation procedure, automatically segmenting the one or more follow-up medical images and extracting anatomical characteristics from the one or more follow-up medical images;
in real time, during the transplantation procedure, updating the patient-specific virtual transplant model based on the automatic segmenting of the one or more follow-up medical images and the extracting of the anatomical characteristics from the one or more follow-up medical images;
estimating an updated blood flow through the updated patient-specific virtual transplant model;
evaluating a risk of an insufficient blood flow to the donor tissue or the donor organ transplanted during the transplantation procedure using the updated patient-specific virtual transplant model; and
outputting the evaluation into an electronic storage medium or display.