Patent ID: 11971415
Assignee: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Field: Measurement (Instruments)
Classification: CPC G  B | IPC B  G

Claim 0:
1. A method for preparing a diagnostic assay device for performing at least one diagnostic assay on a liquid test sample, the diagnostic assay device comprising a reaction vessel having a liquid test sample dispensing device inserted into a portion thereof, wherein the liquid test sample dispensing device is configured for collecting the liquid test sample and dispensing the liquid test sample into the reaction vessel for performing at least one diagnostic assay in the reaction vessel, the method comprising the steps of:
(a) preparing a solution, the solution comprising at least one sample flag compound, at least one protein, at least one sugar, and at least one alcohol solvent, the solution being contained within a receptacle;
(b) placing the liquid test sample dispensing device into the receptacle, the liquid test sample dispensing device comprising:
a capillary portion, the capillary portion comprising a capillary having at least one outer surface, at least one inner surface, a first end, a second end, and an opening located at the second end of the capillary, wherein the capillary is in fluid contact with the solution such that a volume of the solution enters into and is retained within the capillary via the opening such that the solution is in fluid contact with the at least one inner surface of the capillary; and

(c) removing the liquid test sample dispensing device from the receptacle and heating at least the capillary portion of the liquid test sample dispensing device to a temperature wherein the at least one alcohol solvent evaporates from the solution contained within the capillary, and further wherein granules of the at least one sample flag compound are deposited on the at least one inner surface of the capillary, thereby coating the at least one internal surface of the capillary with the at least one sample flag compound; and
(d) inserting and securing the liquid test sample dispensing device in the reaction vessel to form the diagnostic assay device, wherein the reaction vessel comprises at least one sample read window for interrogation of the at least one sample flag compound in the capillary at a first wavelength of light, and wherein the reaction vessel further comprises a reaction chamber containing at least one diagnostic assay reagent that is interrogated at a second wavelength of light that is different from the first wavelength.