Patent ID: 11911449
Assignee: REVANCE THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 12:
13. A pharmaceutical composition comprising liquid carrier, wherein the liquid carrier comprises a botulinum toxin and non-peptide excipients consisting of,
a non-ionic surfactant,
one or more non-reducing sugars selected from non-reducing disaccharides and a non-reducing trisaccharides,
sodium chloride,
a bulking agent, and
a physiologically compatible buffer,
wherein the concentration of the bulking agent is in the range of 5% to 10% w/v and
wherein the ratio of the non-reducing sugar to the bulking agent on a weight percentage basis is in the range of 0.4 to 0.6,
wherein the liquid carrier is formulated such that upon vacuum drying or lyophilization an amorphous solid is formed.