Patent ID: 11866756
Assignee: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A method for co-producing erythritol and arabinose by utilizing a xylose mother liquor, comprising:
obtaining a xylose extract having a high content of xylose component and a xylose raffinate having a high content of glucose component respectively by separating the xylose mother liquor through a first simulated moving bed chromatography, and obtaining xylose crystals by concentrating and crystallizing the xylose extract;
obtaining a concentrated xylose raffinate by concentrating the xylose raffinate, and obtaining a glucose mixture by blending the concentrated xylose raffinate with liquid glucose or crystallized glucose, wherein the concentrated xylose raffinate has a solid content of 30% W/V-50% W/V and a glucose content of 9% W/V-14% W/V, the glucose mixture has a glucose content of 40% W/V-50% W/V;
obtaining a fermentation broth by inoculating a pre-prepared seed solution of a Yarrowia lipolytica into a fermentation medium of a fermenter, while adding the glucose mixture for fermenting, wherein a glucose content of the fermentation broth is less than 0.3% W/V;
obtaining a fermentation filtrate by filtering the fermentation broth, and obtaining erythritol crystals and a centrifuged erythritol mother liquor respectively by decolorizing, ion changing, concentrating, centrifuging and crystallizing a part of the fermentation filtrate in sequence;
obtaining an erythritol extract having a high content of an erythritol component and an erythritol raffinate having a high content of an arabinose component respectively by separating the centrifuged erythritol mother liquor through a second simulated moving bed chromatography, and mixing the erythritol extract with the other part of the fermentation filtrate; and
obtaining arabinose crystals by decolorizing, ion changing, concentrating and crystallizing the erythritol raffinate in sequence.