Patent ID: 11877995
Assignee: IMMUNIC AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  Y | IPC A

Claim 11:
12. A method of treating multiple sclerosis in a subject in need thereof, the method comprising:
a) administering to the subject at least one compound selected from the group consisting of 2-({3-fluoro-3′-methoxy-[1,1′-biphenyl]-4-yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid, a pharmaceutically-acceptable salt and a solvate thereof each day for 5 to 10 days at an initial daily dose of about 5 mg to about 45 mg per day; and thereafter
b) administering to the subject the at least one compound selected from the group consisting of 2-({3-fluoro-3′-methoxy-[1,1′-biphenyl]-4-yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid, a pharmaceutically-acceptable salt and a solvate thereof at a subsequent daily dose,
wherein the subsequent daily dose is 1.5 to 8-fold higher than the initial daily dose, and
wherein the initial daily dose and the subsequent daily dose are calculated based on the weight of 2-({3-fluoro-3′-methoxy-[1,1′-biphenyl]-4-yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid.