Patent ID: 11959108
Assignee: CODEXIS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 14:
15. The recombinant protease of claim 1, wherein the recombinant protease exhibits at least one improved property selected from: i) enhanced catalytic activity; ii) increased tolerance to acid pH; iii) increased tolerance to pH 4 or lower; iv) increased tolerance to pH 5 or greater; v) increased tolerance to at least one protease; vi) increased tolerance to at least one bile salt; vii) increased thermotolerance; viii) increased tolerance to autolysis; or a combination of any of i), ii), iii), iv), v), vi), vii), and viii), as compared to a reference protease having the amino acid sequence of SEQ ID NO: 2.