Patent ID: 11931414
Assignee: SEAGEN INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 2:
3. The Ligand Drug Conjugate compound of claim 1, wherein the Donor Acceptor (DA) Unit has the structure of:, or a salt thereof, wherein each R4 is independently selected from the group consisting of hydrogen and optionally substituted C1-C4 alkyl;
wherein said formal optional cyclization of DA to HN/HN+ is from the sp2 carbon atom of the DA Unit proximal to the carbonyl carbon atom (as indicated) through an introduced optionally substituted non-aromatic carbon atom or an optionally substituted aromatic heteroatom;
the wavy line indicates the site of covalent attachment to HN/HN+; and
the pound sign (#) indicates the site of covalent attachment to IN.