Patent ID: 11950958
Assignee: KONINKLIJKE PHILIPS N.V.
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 0:
1. A method comprising:
transmitting an ultrasound treatment pulse to a treatment region of a subject, the treatment region comprising a plurality of microbubbles;
receiving one or more microbubble echoes comprising a reflection of the ultrasound treatment pulse by the plurality of microbubbles, wherein the received microbubble echoes is distinct from imaging echoes for ultrasonically imaging the treatment region;
identifying, from the received microbubble echoes, at least one microbubble echo signature indicative of a dynamic state of the plurality of microbubbles in response to the ultrasound treatment pulse, wherein the at least one microbubble echo signature comprises at least one of:
a frequency of the received microbubble echoes;
an intensity of the received microbubble echoes; or
a change over time of the intensity of the received microbubble echoes; and

adjusting one or more parameters of an additional ultrasound pulse transmitted to the treatment region based on the at least one microbubble echo signature.