Patent ID: 11884720
Assignee: AMGEN INC.
Field: Biotechnology (Chemistry)
Classification: CPC C  A | IPC C

Claim 9:
10. The bispecific antibody construct according to claim 1, wherein the second binding domain comprises
(a) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 18 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 17;
(b) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 27 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 26;
(c) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 36 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 35;
(d) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 45 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 44;
(e) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 54 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 53;
(f) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 63 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 62;
(g) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 72 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 71;
(h) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 81 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 80;
(i) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 90 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 89;
(j) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 99 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 98; or
(k) a VL region comprising the amino acid sequence set forth in SEQ ID NO: 102 and a VH region comprising the amino acid sequence set forth in SEQ ID NO: 101.