Patent ID: 11925578
Assignee: GLAUKOS CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A drug delivery ocular implant comprising:
an outer shell having a proximal end and a distal end, the outer shell being shaped to define an interior chamber wherein the outer shell comprises a sidewall extending between the distal end and the proximal end;
a first and a second drug positioned within the outer shell;
a drug barrier within the interior chamber, the drug barrier separating the interior chamber into a first subchamber and a second subchamber, the first drug being positioned within the first subchamber and the second drug being positioned within the second subchamber;
a first drug release element positioned within the interior chamber and extending generally perpendicular to the sidewall, the first drug release element configured to release the first drug from the interior chamber, the first drug release element comprising a first membrane;
a second membrane positioned within the interior chamber and extending generally perpendicular to the sidewall, the second membrane configured to release the second drug from the interior chamber; and
a flange positioned at or near the distal end of the outer shell and extending laterally outward a predetermined distance from a first inlet, the first inlet positioned adjacent the flange and between the flange and the proximal end of the outer shell, the first inlet extending laterally through the sidewall of the outer shell, wherein the flange is configured to impede tissue from covering at least a portion of the first inlet,
wherein the first drug release element is configured such that the first drug passes through the first membrane and out the proximal end of the outer shell,
wherein the second membrane is in fluid communication with the second drug within the interior chamber and in fluid communication with an inlet and outlet fluid flow pathway configured to conduct ocular fluid from an ocular chamber to a physiological fluid outflow pathway, such that the second drug passes through the second membrane, through the inlet and outlet fluid flow pathway, and out the distal end of the outer shell.