Patent ID: 11944088
Assignee: TRANSMEDICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 14:
15. A system for perfusing an ex-vivo liver, the system comprising:
a pump configured to pump a perfusion fluid through a perfusion circuit, the pump in fluid communication with a hepatic artery interface and a portal vein interface;
a clamp adapted to be positioned between the pump and the portal vein interface, the clamp configured to be usable to control a pressure of the perfusion fluid provided to the hepatic artery of an ex-vivo liver;
a controller configured to cause the system to:
provide, via the pump and the hepatic artery interface, the perfusion fluid to a hepatic artery of the ex-vivo liver;
provide, via the pump and the portal vein interface, the perfusion fluid to a portal vein of the ex-vivo liver; and
receive a temperature signal from a temperature sensor; and

a heating subsystem configured to maintain a temperature of the perfusion fluid, wherein the heating subsystem comprises:
a heating assembly comprising a heater in communication with the perfusion fluid;
the temperature sensor configured to measure the temperature of the perfusion fluid; and
a driver configured to convert the temperature signal to a heat drive signal,
wherein the heater is configured to heat the perfusion fluid in response to the heat drive signal.