Patent ID: 11918645
Assignee: ALTIMMUNE UK LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A sterile, dried pharmaceutical composition comprising a combination of two or more fluorocarbon-linked peptide constructs, wherein each construct comprises an immunogenic hepatitis B virus peptide sequence covalently attached to a vector for intracellular delivery of the peptide, wherein the vector comprises a chain comprising from 3 to 30 carbon atoms, at least one of which is substituted with fluorine, chlorine, bromine or iodine, and wherein the peptide is from 15 to 60 amino acids in length comprising at least 15 contiguous amino acids shown in any one of SEQ ID NOs: 1 to 4 or SEQ ID No: 55 or of a sequence having at least 90% identity to one of the sequences shown in SEQ ID NOs: 1 to 4 or SEQ ID NO: 55 wherein each peptide comprises at least one CD8+ T-cell epitope and at least one CD4+ T-cell epitope and wherein the peptide binds two or more HLA class 1 alleles; and wherein the mixture is in a solid form.