Patent ID: 11884982
Assignee: CREATIVE BIOSCIENCES (GUANGZHOU) CO.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 13:
14. A method for detecting a colorectal carcinoma or colorectal adenoma in a human subject, comprising:
obtaining an excrement sample from the human subject;
extracting DNA from said excrement sample;
converting the extracted DNA;
amplifying the converted DNA and obtaining a COL4A1 methylation level of an amplification product; and
detecting the presence of the colorectal carcinoma or colorectal adenoma in the human subject when the COL4A1 methylation level of the amplification product is greater in comparison to a COL4A1 methylation level of an amplification product in a control excrement sample from human subjects that do not have said colorectal carcinoma or colorectal adenoma,
wherein said amplifying the converted DNA and obtaining the COL4A1 methylation level of the amplification product comprises:
using the kit of claim 1.