Patent ID: 11903698
Assignee: MEDTRONIC MINIMED, INC.
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 14:
15. An article for use with a plurality of patients, for use with an insulin delivery system, and for use with one or more blood glucose monitoring devices, the article comprising:
a non-transitory storage medium comprising machine-readable instructions stored thereon which are executable by a special purpose computing apparatus to:
for each of the plurality of patients, (i) determine a profile of a blood glucose concentration of the patient based, at least in part, on a probability density function of a plurality of blood glucose concentration values collected at the one or more blood glucose monitoring devices, and (ii) determine a metric based, at least in part, on a convolution of a cost or loss function and the profile, wherein the metric is for balancing short-term and long-term risks associated with a therapy, and wherein the metric is representative of a glycemic health of the patient, the cost or loss function being based, at least in part, on a log-square operation and being further based, at least in part, on a parameter selected to balance Spearman rank coefficients with hypoglycemic-based metrics and hyperglycemic-based metrics, wherein the log-square operation is applied to at least one of a computed mean of the plurality of blood glucose concentration values or a measure of a statistical dispersion of the plurality of blood glucose concentration values,
wherein the profiles of the plurality of patients are obtained under multiple predefined therapies, and
wherein the machine-readable instructions are further executable by the special purpose computing apparatus to:
rank the multiple predefined therapies based, at least in part, on the metrics; and control the insulin delivery system for balancing hypoglycemic and hyperglycemic tendencies in the plurality of patients, based at least in part on the ranking of the multiple predefined therapies.