Patent ID: 11867700
Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC G  H | IPC G  H

Claim 0:
1. A method of measuring lipoprotein particles of at least one subtype of a density class of intact lipoprotein particles present in a sample containing the density class of intact lipoprotein particles, the method comprising:
a) producing lipoprotein ions from the density class of intact lipoprotein particles contained in the sample,
b) simultaneously measuring a charge and a mass-to-charge ratio of each of the lipoprotein ions,
c) determining a mass of each of the lipoprotein ions based on the measured charge and mass-to-charge ratio values thereof,
d) identifying the at least one subtype of the density class of intact lipoprotein particles based on the determined masses and measured charges of the lipoprotein ions, and
e) determining diameters of lipoprotein particles of the identified at least one subtype based on the determined masses and known densities of the lipoprotein particles of the identified at least one subtype.