Patent ID: 11951154
Assignee: FLAGSHIP PIONEERING INNOVATIONS V, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 14:
15. The method of claim 1, wherein the heterologous moiety:
i) possesses at least one targeted function selected from the group consisting of modulates a function, modulates a molecule, and is localized to a specific location;
ii) is or comprises a tag or label;
iii) is selected from the group consisting of an epigenetic modifying agent, epigenetic enzyme, a bicyclic peptide, a transcription factor, a DNA or protein modification enzyme, a DNA-intercalating agent, an efflux pump inhibitor, a nuclear receptor activator or inhibitor, a proteasome inhibitor, a competitive inhibitor for an enzyme, a protein synthesis inhibitor, a nuclease, a protein fragment or domain, a tag or marker, an antigen, an antibody or antibody fragment, a ligand or a receptor, a synthetic or analog peptide from a naturally-bioactive peptide, an anti-microbial peptide, a pore-forming peptide, a targeting or cytotoxic peptide, a degradation or self-destruction peptide, a CRISPR component system or component thereof, DNA, RNA, artificial nucleic acids, a nanoparticle, an oligonucleotide aptamer, a peptide aptamer, and an agent with poor pharmacokinetics or pharmacodynamics (PK/PD); or
iv) is linked, via a linker or directly, to the polypeptide on an N terminus, a C terminus, both termini, or one or more amino acids of the polypeptide.