Patent ID: 11884721
Assignee: ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  B | IPC A  B  C

Claim 13:
14. A method for inducing antigen-specific tolerance to an antigen in a subject, the method comprising:
administering a composition to a subject in an amount effective to induce antigen-specific tolerance, the composition comprising an antigen recombinantly fused or chemically conjugated with an erythrocyte-binding moiety;
wherein the erythrocyte-binding moiety comprises an antibody, antibody fragment, or a single chain variable fragment (scFv) that binds to human glycophorin A; and
wherein the antigen is a self-antigen to which a subject develops an unwanted immune response, and
wherein the self-antigen is associated with multiple sclerosis.