Patent ID: 11918647
Assignee: OSSIANIX, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  G | IPC A  C  G

Claim 0:
1. A transferrin receptor (TfR)-specific conjugate comprising a heterologous molecule operably linked to a TfR-specific binding moiety, wherein said TfR-specific binding moiety comprises a Type 2 VNAR domain capable of specifically binding to human TfR-1, wherein said moiety is capable of cross reacting with mouse TfR-1, and wherein said VNAR domain comprises or consists essentially of a VNAR scaffold with any one CDR1 peptide of SEQ ID NOS. 422, 423, 424, 426, 427, 429 or 434 in combination with any one CDR3 peptide of SEQ ID NOS. 189, 214, 215, 218, 226, 235, 237, 240 or 250.