Patent ID: 11925653
Assignee: FLEURIR ABX, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 19:
20. An antimicrobial fosfomycin composition suitable for oral administration comprising at least three antimicrobial compounds or agents each provided over a course, the at least three antimicrobial compounds or agents comprising:
a fosfomycin;
a sulfonamide; and
a diaminopyrimidine,
such that at least one of the fosfomycin, the sulfonamide and the diaminopyrimidine is in a therapeutically effective amount, and when provided over the course, the at least three antimicrobial compounds or agents inhibit growth of a microorganism or kill the microorganism by a synergistic activity of the at least three antimicrobial compounds or agents,
wherein over the course, the at least three antimicrobial compounds or agents in use display a broad spectrum activity against Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, and parasites, and wherein the microorganism is further selected from any one or more of a drug-resistant aerobic bacteria, a multi-drug resistant aerobic bacteria, a drug-resistant parasite, and a multi-drug resistant parasite, any of which is suspected of causing an infection, including a complicated bacterial infection,
the fosfomycin being provided as a pharmaceutically acceptable salt or ester, any of which have inhibitory activity on cell wall synthesis of the microorganism,
the at least three antimicrobial compounds or agents each being in a pharmaceutically acceptable form in which each of the pharmaceutically acceptable forms is separable or in a premix.