Patent ID: 11873281
Assignee: HANGZHOU DAC BIOTECH CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 1:
2. The conjugate according to claim 1 having Formula (II):, or a pharmaceutically acceptable salt, hydrate, or hydrated salt thereof; or a polymorphic crystalline structure thereof; or an optical isomer, racemate, diastereomer or enantiomer thereof;
wherein T, L, n, m, Y, R1, R2, R3, R4, R5, R6, R8, R10, R13, R14, R15, R16 and R17 are defined the same as in the Formula (I);
wherein R7 is H, R14, —R14C(═O)X1R15; or —R14X1R15; X1 is O, S, S—S, NH, or NR14;
wherein R9 is H, —OH, —OR14, —OC(═O)R14, —OC(═O)NHR14, —OC(═O)NR14R15, —OC(═O) R14SSR15, OP(═O)(OR14)2, or OR14OP(═O)(OR15);
wherein R11 is H, R14, —R14C(═O)R16, —R14C(═O)X2R16, —R14X2R16, or —R14C(═O)X2, wherein X2 is —O—, —S—, —NH—, —NHS(O2), —N(R14)—, —O—R14—, —S—R14—, —S(═O)—R14—, or —NHR14—;
wherein R12 is H, R14, —O—, —S—, —N—, ═N—, ═NNH—, —OH, —SH, —NH2, ═NH, ═NNH2, —NH(R14), —OR14, —C(O)O—, —C(O)OR16—, —COR16, —COOR14—, C(O)NH—, C(O)NH2, C(O)NHR14, —SR14, —S(═O)R14, —P(═O)(OR16)2, —OP(═O)(OR16)2, —CH2OP(═O)(OR16)2, or —SO2R16.