Patent ID: 11938182
Assignee: UTI INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A

Claim 5:
6. A method of inducing Type I interferon (IFN) response in a mammalian subject having a cancerous tumor or a hematologic malignancy that comprises systemically administering a STING dimerization-inducing amount of a halogenated xanthene (HX), a pharmaceutically acceptable salt, an amide thereof whose nitrogen atom is unsubstituted, substituted with one or two C1-C4 alkyl groups that are the same or different or together with the amido nitrogen form a 5- or 6-membered ring, a C1-C4 alkyl ester thereof, an aromatic derivative thereof, wherein the aromatic derivative is an ester or amide formed from an alcohol or monosubstituted amine having a 5- or 6-membered aromatic ring, or a 5,6- or 6,6-fused aromatic ring system that contains 0, 1 or 2 hetero ring atoms that are independently nitrogen, oxygen or sulfur.