Patent ID: 11951449
Assignee: LG HOUSEHOLD & HEALTH CARE LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC B  A  C | IPC A  B  C

Claim 0:
1. A method for preparing an organic-inorganic hybrid microcapsule comprising the steps of:
a first step of preparing a first continuous-phase solution containing inorganic nanoparticles and a second continuous-phase solution containing a polymer precursor 1 for reinforcing an outer wall;
a second step of preparing a dispersed-phase solution containing a polymer precursor 2 which reacts with the polymer precursor 1 or containing an active ingredient and the polymer precursor 2; and
a third step of forming a picketing emulsion by adding the dispersed-phase solution to the first solution, and then forming an outer wall of the capsule through interfacial polymerization by adding the second solution,
wherein the outer wall of the capsule comprises i) at least one polymer selected from the group consisting of polyamide, polyurethane, polyurea, polyester and poly(β-amino ester), and ii) inorganic nanoparticles; and
the polymer precursor 1 for reinforcing the outer wall and the polymer precursor 2 each independently contain at least one precursor for forming a polymer selected from the group consisting of polyamide, polyurethane, polyurea, polyester, and poly(β-amino ester),
wherein the polymer precursor 2 is at least one selected from the group consisting of a compound containing two or more acid chloride structures represented by the Chemical Formula 3, and a compound containing two or more chloroformate structures represented by the following Chemical Formula 5:, (in Chemical Formula 3, each R3 may independently comprise C1 to C50 alkylene, a C3 to C60 cyclic hydrocarbon group, or C1 to C50 alkylene and a C3 to C60 cyclic hydrocarbon group having or not having at least one acid chloride (-COCl) or at least one heteroatom), (in Chemical Formula 5, each R5 may independently comprise C1 to C50 alkylene, a C3 to C60 cyclic hydrocarbon group, or C1 to C50 alkylene and a C3 to C60 cyclic hydrocarbon group having or not having at least one chloroformate (-OCOCl) or at least one heteroatom).