Patent ID: 11952636
Assignee: VISBY MEDICAL, INC.
Field: Measurement (Instruments)
Classification: CPC C  G | IPC C

Claim 8:
9. A detection module of a molecular diagnostic device configured to detect the presence of a target organism and the presence of at least one of a first target allele within the target organism associated with resistance to a treatment or a second target allele within the target organism associated with susceptibility to the treatment, the detection module comprising:
a flow member defining a detection channel configured to receive an output solution from an amplification module, the output solution containing a first amplicon comprising a first genetic locus in a polynucleotide associated with the target organism and a second amplicon comprising a second genetic locus in a polynucleotide associated with a single nucleotide polymorphism (SNP) locus in the polynucleotide;
a first detection surface within the detection channel, a first probe being adhered to the first detection surface, the first probe designed to bind to the first genetic locus in a polynucleotide associated with the target organism and facilitate production of a first signal indicating the presence of the target organism;
a second detection surface within the detection channel, a second probe being adhered to the second detection surface, the second probe designed to bind to the second genetic locus if the second genetic locus comprises the first target allele and facilitate production of a second signal indicating the presence of the first target allele within the target organism associated with resistance to the treatment; and
a third detection surface within the detection channel, a third probe being adhered to the third detection surface, the third probe designed to bind to the second genetic locus if the second genetic locus comprises the second target allele and facilitate production of a third signal indicating the presence of the second target allele within the target organism associated with susceptibility to the treatment.