Patent ID: 11964057
Assignee: RJH BIOSCIENCES INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 11:
12. The nanoparticle of claim 11, wherein the target gene of siRNA is selected from KIF11, FLT3, STAT3, STAT5A/B, RRM2, FLT1, RUNX1, Cyclin A2, Hsp70, p65, p100/52 (NfκB ), HIF-1a, GFI-1B, Hsp27, Hsp32, CXCR4, CD44, Nucleoplasmin gene, a gene encoding an inhibitor of DNA binding protein, CD22, MAX dimerization protein 3 (MDX3) gene, or a fusion gene selected from AML1-ETO, BCR-ABL, BCR-JAK2, BCR-FGFR1, CEP110-FGFR1, ERG, EWS-FLI1, TEL-AML1, ETV6-ABL, ETV6-PDGFRB, ETV6-JAK2, ETV6-SYK2, EWS-ERG, FOP-FGFR1, HIP1-PDGFRB, H4-PDGFRB, MLL/ENL, MLLT10/AF10, MLL/AF9, a fusion gene comprising MLL, MYH11-CBFB, NUP98-NSD1, PAX3-FKHR, PML-RARA, RAB5-PDGFRB, RUNX1-RUNX1T1, TLS-FUS, or ZNF198-FGFR1.