Patent ID: 11866745
Assignee: PAIRWISE PLANTS SERVICES, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 1:
2. The modified LbCas12a polypeptide of claim 1, wherein the modified LbCas12a polypeptide comprises a further mutation located at one or more of the following positions of K116, K120, K121, D122, E125, T148, T149, T152, D156, E159, Q529, D535, G532, K538, D541, Y542, L585, K591, M592, V596, S599, K600, K601, Y616, Y646, and/or W649 Y616K, Y616R, Y616E, Y616F, Y616H, Y646R with reference to position numbering of SEQ ID NO:1.