Patent ID: 11858975
Assignee: ZHEJIANG DOER BIOLOGICS CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 10:
11. A composition, comprising a multi-domain active protein and a pharmaceutically acceptable carrier, wherein the multi-domain active protein comprises a structure shown in Formula I: A-La-F-Lb-B, A is a GCGR/GLP-1R dual-agonist active peptide, F is a long-acting protein unit, B is a native FGF21 or FGF21 analogue, La does not exist or is a peptide linker, Lb does not exist or is a peptide linker; and
wherein an amino acid sequence of the A is selected from SEQ ID NO: 57 and SEQ ID NO: 66.