Patent ID: 11952575
Assignee: ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 1:
2. The transaminase mutant according to claim 1, wherein the mutations at one or more amino acids comprise any one of the following combinations:
V379L/M/T+F89Y/W, V379L/M/T+R416A/C/H/Q/T/S, V379L/M/T+A417S, V379L/M/T+C418A/Q/S, V379L/M/T+P243E, V379L/M/T+K193E, V379L/M/T+V234I, V379L/M/T+I262V, V379L/M/T+Q280K, V379L/M/T+R416A/C/H/Q/T/S+F89Y/W, V379L/M/T+R416A/C/H/Q/T/S+A417S, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S, V379L/M/T+R416A/C/H/Q/T/S+K193E, V379L/M/T+R416A/C/H/Q/T/S+V234I, V379L/M/T+C418A/Q/S+F89Y/W, V379L/M/T+C418A/Q/S+P243E, V379L/M/T+C418A/Q/S+I262V, V379L/M/T+A417S+Q280K, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+F89Y/W, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+Q280K, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+F89Y/W+Q280K, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+F89Y/W+Q280K+I262V, V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+F89Y/W+Q280K+A417S and V379L/M/T+R416A/C/H/Q/T/S+C418A/Q/S+F89Y/W+Q280K+I262V+V234I.