Patent ID: 11859005
Assignee: ELI LILLY AND COMPANY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. A compound comprising X, wherein X is an antigen binding fragment that binds human GITR (SEQ ID NO: 20) and comprises a heavy chain variable region (VH) and a light chain variable region (VL), wherein the VH comprises heavy chain complementarity determining regions HCDR1, HCDR2, and HCDR3, and the VL comprises light chain complementarity determining regions LCDR1, LCDR2, and LCDR3, wherein
i. the HCDR1 comprises SEQ ID NO: 1,
ii. the HCDR2 comprises SEQ ID NO: 2 or SEQ ID NO: 7,
iii. the HCDR3 comprises SEQ ID NO: 3,
iv. the LCDR1 comprises SEQ ID NO: 4,
v. the LCDR2 comprises SEQ ID NO: 5, and
vi. the LCDR3 comprises SEQ ID NO: 6.