Patent ID: 11905229
Assignee: FUDAN UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  B  Y | IPC B  C

Claim 6:
7. The method of claim 1, wherein in step (S5), the Lewis acid catalyst is selected from the group consisting of aluminum chloride, ferric chloride, zinc chloride, zinc bromide and tin tetrachloride;
a molar ratio of N-(2,6-dichlorophenyl)-2-chloro-N-phenylacetamide (V) to the Lewis acid catalyst is 1:(0.5-5);
the Friedel-Crafts alkylation is performed in a solvent-free manner or in the presence of an organic solvent selected from the group consisting of dichloromethane, 1,2-dichloroethane, chlorobenzene, toluene, xylene, dichlorobenzene, 1-butanol or diphenyl ether; and
the Friedel-Crafts alkylation is performed at 50-200° C. for 1-10 h.