Patent ID: 11925712
Assignee: SORRENTO THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 5:
6. A fully implantable delivery device for delivery of a bioactive agent to a subject, the device comprising:
a wall having a surface;
a plurality of nanostructures extending from the surface of the wall, at least a portion of the nanostructures having a cross-sectional dimension of greater than about 5 nanometers and less than about 500 nanometers, and a height of greater than about 5 nanometers to less than about 1 micrometer, and wherein at least a portion of the nanostructures have a center-to-center spacing of greater than about 50 nanometers to less than about 1 micrometer,
a plurality of microstructures extending from the surface of the wall, at least a portion of the microstructures having a cross-sectional dimension of greater than about 500 nanometers and less than about 10 micrometers and a height of from about 20 nanometers to about 1 micrometer; and
a reservoir defined by the wall and containing the bioactive agent suitable for delivering to the subject using the implantable delivery device,
wherein the entire implantable delivery device is suitable for implanting in the subject and configured to interact with tissue near a site of implantation within the subject;
wherein the plurality of nanostructures and plurality of microstructures are arranged in a fractal dimension of greater than about 1.