Patent ID: 11932843
Assignee: TRIZELL LIMITED
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. An adherent cell culture bioreactor comprising:
a bioreactor container having a bioreactor container wall defining a bioreactor container exterior and a bioreactor container interior, the bioreactor container interior able to aseptically contain liquid cell culture media and a solid substrate for adherent cell culture,
a port disposed through the bioreactor container wall to enable communication between the bioreactor container exterior and the bioreactor container interior,
a sampling device housing aseptically connected to the port, wherein the sampling device housing comprises a sampling device housing exterior and a sampling device housing interior, wherein the sampling device housing is disposed on the port so that the sampling device housing interior can be in aseptic communication with the bioreactor container interior, and
a solid substrate sampling device contained within the sampling device housing in the sampling device housing interior,
wherein at least a portion of the sampling device can be passed from the sample device housing interior through the port into the bioreactor container interior to aseptically obtain a sample of solid substrate contained in the bioreactor container interior.