Patent ID: 11951479
Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Field: Biotechnology (Chemistry)
Classification: CPC B  C | IPC B  C

Claim 0:
1. A method for inhibiting, delaying, or reversing cellular senescence, comprising:
having an isolated cell flow; and
crashing the cell into an impact surface installed on a flow path of the cell to apply a physical impact to the cell, whereby a reorganization of cytoskeleton occurs in the cell without causing cell death,
wherein the having an isolated cell flow is performed by injecting a fluid containing the cell into a microchannel to flow in accordance with a predetermined parameter (Re),
wherein the parameter (Re) is determined by Equation 1:

Re=ρVD/μ  (Equation 1)

wherein, in Equation 1, ρ is a density of the fluid, V is a velocity of the fluid, D is a characteristic length of the fluid, and μ is a viscosity coefficient of the fluid, and
wherein the parameter (Re) has a value of from 75 to 290.