Patent ID: 11932634
Assignee: GILEAD SCIENCES, INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC A  C | IPC C

Claim 0:
1. A compound of Formula (I):, or a pharmaceutically acceptable salt thereof, wherein
R1 is hydrogen, C1-6 alkyl, or halogen;
R2 is hydrogen, C1-6 alkyl, or halogen;
R3 is hydrogen, C1-6 alkyl, or halogen;
R4 is hydrogen, C1-6 alkyl, or halogen;
R7 is hydrogen or C1-6 alkyl optionally substituted with —OH;
R5 is C1-6 alkyl or C1-6 haloalkyl;
R6 is phenyl substituted with C2-8 alkynyl, the alkynyl is substituted with 1 or 2 R6j which can be the same or different; the phenyl of R6 is optionally substituted with one additional R6a;, or, , is, , n is 0, 1, or 2;
each R6a is independently halogen, C2-8 alkynyl, phenyl, heterocycloalkyl, or heteroaryl, wherein the phenyl, heterocycloalkyl, or heteroaryl is each optionally substituted with 1 to 3 R6e, and the alkynyl is optionally substituted with 1 to 4 R6j which can be the same or different, wherein the heterocycloalkyl is a 3 to 10 membered ring having 1 to 3 heteroatoms each independently N, O or S, and the heteroaryl is a 5 or 6 membered ring having 1 to 3 heteroatoms each independently N, O or S;
each R6j is independently halogen, C1-6 haloalkyl, —OR6j1, —CN, —N(R6j1)(R6j2), —N(R6j1)C(O)R6j2, C3-10 cycloalkyl, heteroaryl, or heterocycloalkyl, wherein the cycloalkyl, heteroaryl, or heterocycloalkyl is optionally substituted with 1 to 3 R6p which can be the same or different, the heterocycloalkyl is a 3 to 10 membered ring having 1 to 3 heteroatoms each independently N, O or S; and the heteroaryl is a 5 or 6 membered ring having 1 to 3 heteroatoms each independently N, O or S;
each R6j1 and R6j2 independently hydrogen, C1-6 alkyl, C1-6 haloalkyl, or C3-10 cycloalkyl optionally substituted with C1-6 haloalkyl;
each R6p is independently halogen, C1-6 alkyl, C1-6 haloalkyl, —C(O)R6p1, or heterocycloalkyl, the heterocycloalkyl is a 3 to 10 membered ring having 1 to 3 heteroatoms each independently N, O or S;
R6p1 is C1-6 alkyl, or C3-10 cycloalkyl;
each R6e is independently C1-6 alkyl, C3-6 cycloalkyl, heterocycloalkyl, halogen, C1-6 haloalkyl, or —CN, wherein the cycloalkyl and heterocycloalkyl are optionally substituted with 1 to 3 R6h which can be the same or different, and the heterocycloalkyl is a 3 to 10 membered ring having 1 to 3 heteroatoms each independently N, O or S;
and each R6h is independently C1-6 alkyl, C1-6 haloalkyl, ═O, or —OH.