Patent ID: 11957853
Assignee: UROTRONIC, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 20:
21. A method for reduction of the occurrence of a surgical anastomosis-induced stricture, the method comprising:
providing a balloon catheter in a surgical anastomosis, wherein the surgical anastomosis comprises an anastomosis between two portions of a body structure, or between two different body structures, wherein the one or more body structures are independently chosen from an esophagus, biliary tract, stomach, small intestine, duodenum, jejunum, ileum, colon, rectum, large intestine, colon, and a rectum, the balloon catheter comprising a balloon and a coating layer overlying an external surface of the balloon, the coating layer comprising a hydrophobic therapeutic agent and one or more water-soluble additives;
inflating the balloon in the surgical anastomosis so that the coating layer contacts walls of the surgical anastomosis and the therapeutic agent is delivered to the walls of the surgical anastomosis;
deflating the balloon after an inflation period;
withdrawing the balloon catheter from the surgical anastomosis;
wherein the balloon catheter provided in the surgical anastomosis is a soaked balloon catheter, wherein the balloon catheter is soaked outside the body with a soaking solution comprising water or saline, or the balloon catheter is soaked in the stricture with a flushing solution comprising water or saline, or a combination thereof.