Patent ID: 11878044
Assignee: NONO INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 17:
18. A method of treating a subject population of humans subjects presenting sign(s) and/or symptom(s) of stroke, comprising administering a PSD-95 inhibitor comprising a peptide comprising SEQ ID NO:38 or SEQ ID NO:68 at its C-terminus, the peptide being linked to an internalization peptide, to the human subjects; wherein the human subjects are analyzed for unacceptable risk of side effects of reperfusion therapy, some of the subjects having unacceptable risk of side effects of reperfusion therapy and some of the subjects not having unacceptable risk of side effects of reperfusion therapy, and the human subjects without unacceptable risk of side effects receive reperfusion therapy and the human subjects with unacceptable risk of side effects do not receive reperfusion therapy, and wherein in the human subjects without unacceptable risk of side effects receiving reperfusion therapy, the reperfusion therapy and the PSD-95 inhibitor synergistically treat the stroke.