Patent ID: 11918600
Assignee: SUZHOU RIBO LIFE SCIENCE CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 12:
13. The siRNA according to claim 1, wherein the nucleotide at 5′-terminal of the antisense strand of the siRNA is a 5′-phosphate nucleotide or a 5′-phosphate analogue modified nucleotide, wherein the 5′-phosphate nucleotide or 5′-phosphate analogue modified nucleotide has a structure as shown by one of Formula (202), (203), (204), (205) or (206):, wherein R represents a group selected from the group consisting of H, OH, F and methoxy: “Base” represents a base selected from A, U, C, G, and T.