Patent ID: 11896043
Assignee: DAICEL CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  G  Y | IPC A  G

Claim 1:
2. The method for increasing and maintaining of IgA in the intestinal tract according to claim 1, wherein the cellulose acetate has a compositional distribution index (CDI) of 2.0 or less, the compositional distribution index (CDI) being defined by the equation below:

CDI=(Measured value of half width of compositional distribution/(Theoretical value of half width of compositional distribution)

wherein the measured value of half width of compositional distribution is a half width of compositional distribution determined by high-performance liquid chromatographic analysis of a cellulose acetate propionate obtained by propionylation of all residual hydroxyl groups of a cellulose acetate,
where DS is the total degree of acetyl substitution; and

the theoretical value of half width of compositional distribution=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw 

Dpw is a weight average degree of polymerization determined by gel permeation chromatography-light scattering method using a cellulose acetate propionate obtained by propionylation of all residual hydroxyl groups of the cellulose acetate.