Patent ID: 11965886
Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
Field: Measurement (Instruments)
Classification: CPC G  C | IPC C  G

Claim 1:
2. The method of claim 1,
wherein the hydrophilic domain of the compound has the formula of Formula (I):

X1-[A1-(L1)n]k1-Z-[A2-(L1)n]k2-X2  (I),

wherein
Z is linear polyethylene glycol (PEG) moiety containing 1 to 100 —O—CH2—CH2— moieties, wherein the polyethylene glycol moiety optionally comprises 1 or more spacer moieties SP connecting two —O—CH2—CH2— moieties, and wherein the linear PEG moiety optionally comprises a linker moiety L3 at one or both ends,
each L1 is a linker moiety selected independently from each other from the group consisting of phosphate, amide, carbamate, and ester,
each n is either 0 or 1, selected independently from each other,
A1 and A2 are bifunctional or trifunctional moieties selected independently from each other, and at least one A1 or A2 is trifunctional,
k1 and k2 are integers between 0 and 10, selected independently from each other, and at least one of k1 and k2 is not 0,
X1 and X2 are independently selected from hydrogen or a protecting group,
L3 is independently selected from a linear alkyl or alkenyl chain with 1 to 10 C atoms, which is optionally (i) interrupted by 1 to 3 N, O or S atoms, and/or (ii) substituted by 1 to 4 hydroxyl, carbonyl, amino or thiol groups,
and
wherein the two, three or four hydrophobic domains are independently covalently bound to said hydrophilic domain via the trifunctional moieties.