Patent ID: 11911348
Assignee: THERAVALUES CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method for treating colon cancer in a subject having cancer, comprising
administering simultaneously or separately at least one selected from the group consisting of curcumin and a derivative thereof, and at least one anti-PD-1 antibody comprising RMP1-14 CDR1, RMP1-14 CDR2 and RMP1-14 CDR3 of heavy chain and RMP1-14 CDR1, RMP1-14 CDR2 and RMP1-14 CDR3 of the light chain and the framework sequences to inhibit immunosuppressive signal by PD-1,
wherein the derivative thereof is selected from the group consisting of desmethoxycurcumin, bisdesmethoxycurcumin and tetrahydrocurcumin.