Patent ID: 11865542
Assignee: nan
Field: Measurement (Instruments)
Classification: CPC B  C  G | IPC B  C  G

Claim 0:
1. A method for capturing and processing nucleic acid material comprising:
within an array of wells defined within a substrate, isolating genetic material from a sample,
wherein each well in the array of wells extends into a planar surface of the substrate, the substrate further comprising a fluid pathway in fluid communication with and passing across the array of wells, the fluid pathway at least partially defined at the planar surface, and wherein the array of wells comprises at least 10,000 wells within an area of the substrate, wherein isolating genetic material from the sample comprises isolating genetic material with a population of probe-coupled particles at the array of wells, at greater than 80% capture efficiency of the population of probe-coupled particles, within the array of wells, upon flow of the sample with the population of probe-coupled particles to the array of wells;

delivering one or more process reagents into the fluid pathway and to the array of wells;
distributing a layer of oil across open surfaces of the array of wells, thereby preventing contents of each well from transferring to adjacent wells of the array of wells;
transmitting heat to the substrate and to the array of wells, thereby processing said genetic material;
illuminating the substrate and the array of wells; and
optically interrogating contents of each well of the array of wells.