Patent ID: 11964048
Assignee: nan
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. An osmotic, floating, gastroretentive composition comprising:
a) a multilayer core comprising:
(i) a pull layer comprising liothyronine or a pharmaceutically acceptable salt thereof, an acid, and a gas-generating agent, and
(ii) a push layer; and
b) a permeable, elastic membrane comprising at least one orifice and covering at least a portion of the multilayer core;
wherein the permeable, elastic membrane comprises a copolymer of ethyl acrylate, methyl methacrylate and trimethylammonioethyl methacrylate chloride, and a plasticizer,
wherein the composition comprises an osmogen in either the pull layer, the push layer, or both,
wherein the at least one orifice is in fluid communication with the pull layer, and
wherein the composition does not include a semipermeable membrane.