Patent ID: 11942209
Assignee: I.D. THERAPEUTICS LLC
Field: Medical technology (Instruments)
Classification: CPC G  Y | IPC G

Claim 17:
18. A method of optimizing treatment of a kidney transplant recipient, comprising:
administering at least one immunosuppressant medication comprising cyclosporin A to a kidney transplant recipient as a part of an immunosuppressant treatment regimen;
providing the kidney transplant recipient with a reprogrammable medication monitor capable of providing usage data regarding the kidney transplant recipient's compliance with the immunosuppressant treatment regimen, the immunosuppressant treatment regimen being established based on a medication compliance pattern of the kidney transplant recipient, wherein the compliance pattern is a statistical pattern derived from a plurality of data points gathered over a period of time of not less than one week, where the data points include doses missed, doses taken early, doses taken late, and taken on time,
the medication monitor including:
a housing body that includes a housing for containing medication or medication packaging, the housing body defining an opening to accommodate insertion and removal of the medication or of the medication packaging, and
a removal sensor that senses at least one of (1) removal of the medication or of the medication packaging and (ii) opening of the housing body;

collecting the usage data from the medication monitor at a central server over a predetermined period of time;
determining safety and efficacy of the immunosuppressant treatment regimen;
determining the kidney transplant recipient's pattern of compliance with the immunosuppressant treatment regimen based on the usage data collected from the medication monitor;
obtaining diagnostic test results from a biomarker device, the diagnostic test results being indicative of a level of immunosuppression of the kidney transplant recipient to the immunosuppressant treatment regimen over the predetermined period of time,
the biomarker device being configured to be implanted in the kidney transplant recipient or provided external to the kidney transplant recipient;

correlating the kidney transplant recipient's pattern of compliance with patterns of compliance from a population of kidney transplant recipients to obtain a correlation;
outputting at least one recommendation based on the correlation, the at least one recommendation including reducing a dose of the at least one immunosuppressant medication used in the immunosuppressant treatment regimen; and
adjusting and administering the immunosuppressant treatment regimen of the kidney transplant recipient based on the at least one recommendation.