Patent ID: 11939331
Assignee: INCYTE CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 8:
9. The compound of claim 1, or a pharmaceutically acceptable salt thereof, wherein R1 is selected from H, 1-(2-hydroxyethyl)-1H-pyrazol-4-yl, 1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl, 1-(1-amino-2-methyl-1-oxopropan-2-yl)-1H-pyrazol-4-yl, 4-(morpholine-4-carbonyl)phenyl, 1H-pyrazol-4-yl, 1-(1-cyanopropan-2-yl)-1H-pyrazol-4-yl, 1-(2-hydroxybutyl)-1H-pyrazol-4-yl, 1-((4-fluorotetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl, 1-((5-cyanopyridin-3-yl)methyl)-1H-pyrazol-4-yl, 1-((2-cyanopyridin-4-yl)methyl)-1H-pyrazol-4-yl, 1-(pyrimidin-4-ylmethyl)-1H-pyrazol-4-yl, 1-(1-(2-cyanopyridin-4-yl)ethyl)-1H-pyrazol-4-yl, 4-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)phenyl, 4-(1,1-dioxidothiomorpholino)phenyl, 1-(pyrimidin-2-ylmethyl)-1H-pyrazol-4-yl, 1-((6-cyanopyridin-2-yl)methyl)-1H-pyrazol-4-yl, 4-(4-acetylpiperazin-1-yl)phenyl, 4-(4-(2-hydroxyacetyl)piperazin-1-yl)phenyl, 4-((4-acetylpiperazin-1-yl)methyl)phenyl, 4-((4-(2-hydroxyacetyl)piperazin-1-yl)methyl)phenyl, 4-(4-methylpiperazin-1-yl)phenyl, 4-((1S,4S)-2-oxa-5-azabicyclo [2.2.1]heptane-5-carbonyl)phenyl, 1-(cyanomethyl)-1H-pyrazol-4-yl, 1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl, 1-benzyl-1H-pyrazol-4-yl, 1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl, 1-(1-cyanoethyl)-1H-pyrazol-4-yl, 1-(2,2-difluoroethyl)-1H-pyrazol-4-yl, 1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl, 1-(1-hydroxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl, 1-(2-cyanopropan-2-yl)-1H-pyrazol-4-yl, 1-cyclopropyl-1H-pyrazol-4-yl, 1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl, 1-(2-(dimethylamino)ethyl)-1H-pyrazol-4-yl, 1-(1-methoxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl, 9-(1-(2-hydroxypropyl)-1H-pyrazol-4-yl, 1-(3-(dimethylamino)propyl)-1H-pyrazol-4-yl, 1-methyl-1H-imidazol-4-yl, 6-oxo-1,6-dihydropyridin-3-yl, 5-isopropyl-1H-pyrazol-4-yl, 5,6-dihydro-4H-pyrrolo [1,2-b]pyrazol-3-yl, 5-(2-hydroxypropan-2-yl)pyridin-3-yl, 2-(methylamino)pyrimidin-5-yl, 1-(tetrahydrofuran-3-yl)-1H-pyrazol-4-yl, 1-(2-morpholinoethyl)-1H-pyrazol-4-yl, 1-(2-(4-methylpiperazin-1-yl)ethyl)-1H-pyrazol-4-yl, 1-(3-hydroxypropyl)-1H-pyrazol-4-yl, 1-(2-cyanoethyl)-1H-pyrazol-4-yl, 1-(2-Amino-2-oxoethyl)-1H-pyrazol-4-yl, 6-(2-hydroxypropan-2-yl)pyridin-3-yl, 6-(2,2,2-trifluoroethyl)pyridin-3-yl, 6-(methylcarbamoyl)pyridin-3-yl, 4-hydroxycyclohex-1-en-1-yl, 5-hydroxypent-1-yn-1-yl, and 2-hydroxypropan-2-yl.