Patent ID: 11931422
Assignee: HELIX BIOPHARMA CORP.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 23:
24. A pharmaceutical composition comprising:
a single domain antibody-urease conjugate having a conjugation ratio of 3, 4, 5, 6, 7, 8, 9, 10, 11, or 12 single domain antibody moieties per urease moiety, wherein each of said single domain antibodies is specific for binding to CEACAM6 and is represented by an amino acid sequence of SEQ ID NO: 1 or an amino acid sequence sharing at least 95% sequence identity with SEQ ID NO: 1 that maintains binding specificity to CEACAM6, wherein the conjugate has urease activity; and
less than 5% unconjugated urease.