Patent ID: 11925688
Assignee: THETIS PHAMACEUTICALS LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method for treating colon cancer in a subject in need of such treatment, the method comprising administering to the subject a pharmaceutical composition comprising a compound of Formula IV, or an enantiomer, polymorph, solvate, or hydrate thereof, and a carrier:, wherein
M is a divalent metal selected from magnesium (Mg2+), calcium (Ca2+), and zinc (Zn2+),
A and B are each an SPM molecule selected from an E series resolvin, a D series resolvin, and their aspirin-triggered counterparts,
R1 and R2 are each independently —(CH2)3—Y1, and —(CH2)4—Y2,
where Y1 and Y2 are each a basic function selected from a positively charged primary amine, a positively charged secondary amine, a positively charged tertiary amine, and a positively charged guanidine,

X1 and X2 are each independently H or CO—Z and Z is a peptide comprising 1 to 5 amino acids.