Patent ID: 11891413
Assignee: IDORSIA PHARMACEUTICALS LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G | IPC A  C  G

Claim 0:
1. An oligosaccharide of general formula (II)

T*-[(—Ux+4—Ux+3—Ux+2—Ux+1—Ux)m—(Vx+2—Vx+1—Vx)1-m]n—O-L-E  (II)

wherein
m is an integer selected from 0 and 1;
x is 1;
n is an integer selected from 2, 3, 4, 5, 6, 7, and 8;, T*- represents H—;
-L- represents -La-, -La-Le-, -La-Lb-Le-, or -La-Ld-Le-;
-La- represents —(CH2)o—, —(CH2—CH2—O)o—C2H4—, or —(CH2—CH2—O)o—CH2;
-Lb- represents —O—, —NH—CO—NH—, —NH—CO—CH2—NH—, —NH—CO—;
-Ld- represents —(CH2)q—, —(CH(OH))q—, —(CF2)q—, —(CH2—CH2—O)q—C2H4—, or —(CH2—CH2—O)q—CH2—;
-Le- represents —(CH2)p1—, —(CF2)p1—, —C2H4—(O—CH2—CH2)p1—, —CH2—(O—CH2—CH2)p1— or —(CH2)p1—O—(CH2)p2—; and
o, q, p1 and p2 are independently of each other an integer selected from 1, 2, 3, 4, 5, and 6;
E represents —NH2, —N3, —CN, —O—NH2, —CH═CH2, —C≡CH, —Br, —Cl, —I, —CO2R′, —COR′, —CONH—NH2, —SH, or —SAc;
R′ represents —H, -Me, -Et, 4-nitrophenyl, pentafluorophenyl, —N-hydroxysuccinimidyl, -(3-sulfo-N-hydroxysuccinimidyl), or -(dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl);
or a pharmaceutically acceptable salt thereof.