Patent ID: 11920930
Assignee: CORNELL UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC G  A | IPC A  G

Claim 0:
1. A system for providing optical actuation and optical sensing, comprising:
an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam that propagates along a sampling-beam path and interacts with the sample and an optical reference beam;
an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the optical reference beam;
a light source that produces an optical actuation beam that propagates along an actuation-beam path before being coupled with the optical sampling beam to be directed to the sample to actuate particles or structures in the sample so that the optical imaging captures information of the sample under the optical actuation;
an optical beam shaping module located in the actuation-beam path between the light source and the sample to shape the optical actuation beam into a light-sheet to illuminate a region of the sample;
a fluorescent excitation light source to produce a fluorescent excitation light to the sample to cause the sample to emit fluorescent light;
a scanner that is (i) on the sampling-beam path, (ii) not on the actuation-beam path, and (iii) scans the optical sampling beam over the sample in performing the optical imaging; and
a fluorescent detection module located to receive the emitted fluorescent light from the sample to measure one or more properties of the sample from the emitted fluorescent light, wherein the fluorescent detection module includes:
different optical filters to receive different portions of the emitted fluorescent light from the sample to filter the received different portions to generate filtered fluorescent beams at different center optical wavelengths, respectively; and
different optical detectors located to receive the filtered fluorescent beams at different center optical wavelengths, respectively, to capture sample information from the filtered fluorescent beams at different center optical wavelengths.