Patent ID: 11896704
Assignee: LUBRIZOL ADVANCED MATERIALS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A compound of formula (I):, (I)

R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-

 

Zq-R2 (R1-Wm-Xn-[SEQ ID NO. 1]-Yp-Zq-R2),

its stereoisomers and/or its cosmetically or pharmaceutically acceptable salts, wherein:
AA1 is Phe;
AA2 is Trp;
AA3 is selected from the group consisting of Met, Leu and Ile;
AA4 is selected from the group consisting of Lys, Arg and Gln;
AA5 is Arg;
AA6 is Lys;
AA7 is selected from the group consisting of Arg, Lys and His;
AA8 is selected from the group consisting of Val, Ile, Leu and Met; and
AA9 is Pro;
W, X, Y and Z are each independently an amino acid;
m, n, p and q are each independently 0 or 1;
m+n+p+q is less than or equal to 2;
R1 is selected from the group consisting of H, a polymer derived from polyethylene glycol, a non-cyclic aliphatic group, alicyclyl, heterocyclyl, heteroarylalkyl, aryl, aralkyl and R5—CO—, wherein R5 is selected from the group consisting of H, a non-cyclic aliphatic group, alicyclyl, aryl, aralkyl, heterocyclyl and heteroarylalkyl;
R2 is selected from the group consisting of —NR3R4, —OR3, —SR3, wherein R3 and R4 are independently selected from a group consisting of H, a polymer derived from polyethylene glycol, a non-cyclic aliphatic group, alicyclyl, heterocyclyl, heteroarylalkyl, aryl and aralkyl; and
R1 and R2 are not amino acids.