Patent ID: 11958903
Assignee: NANJING LEGEND BIOTECH CO., LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 14:
15. The anti-LAG-3 construct of claim 12, wherein the second antigen binding portion specifically recognizes an immune checkpoint molecule selected from the group consisting of programmed cell death receptor 1 (PD-1), tumor necrosis factor receptor superfamily member 9 (4-1BB), programmed cell death 1 ligand 1 (PD-L1), T cell membrane protein 3 (TIM-3), T cell immunoreceptor with Ig and ITIM domains (TIGIT), cytotoxic T-lymphocyte antigen 4 (CTLA-4), V-domain immunoglobulin (Ig)-containing suppressor of T-cell activation (VISTA), B7-1, B7-H3, cluster of differentiation 47 (CD47), tumor necrosis factor receptor superfamily member 4 (OX40) and glucocorticoid-induced tumor necrosis factor receptor (GITR).