Patent ID: 11860120
Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
Field: Measurement (Instruments)
Classification: CPC G  H | IPC G  H

Claim 15:
16. A method, comprising:
forming a plurality of sensing pixels in a semiconductor layer, wherein forming each of the sensing pixels comprises:
forming source/drain regions in the semiconductor layer that is disposed on a dielectric layer; and
forming a temperature-sensing device in the semiconductor layer;
forming a plurality of first elongated heaters in the semiconductor layer;
forming a gate structure over a front-side of a channel region between the source/drain regions;
forming an interconnect structure over the gate structure, wherein the interconnect structure comprises a plurality of second elongated heaters, wherein from a top view the first elongated heaters extend along a first direction, the second elongated heaters extend along a second direction perpendicular to the first direction, and the sensing pixels are respectively in regions defined by the first elongated heaters and the second elongated heaters;
etching the dielectric layer to form a sensing well over a backside of the channel region;
forming a biosensing film lining the sensing well;
forming a biological material coating layer lining the biosensing film;
forming an access transistor in the semiconductor layer, wherein the biological material coating layer vertically overlaps both the access transistor and the sensing pixels, and a vertical distance from the biological material coating layer to a channel region of the access transistor is greater than a vertical distance from the biological material coating layer to the channel region of one of the sensing pixels; and
forming fluid channel walls over the biological material coating layer, wherein one of the fluid channel walls forms a horizontal interface with the biological material coating layer, and an entirety of the horizontal interface vertically overlaps with one of the plurality of first elongated heaters in the semiconductor layer.