Patent ID: 11945800
Assignee: KING FAISAL UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 5:
6. A method of making the 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((5-oxo-2-phenyl-4-(quinolin-2-ylmethylene)-4,5-dihydro-1H-imidazol-1-yl)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid compound of claim 1, the method comprising:
stirring a solution of 2-phenyl-4-(quinolin-2-ylmethylene)-1H-imidazol-5(4H)-one and formaldehyde in ethanol to obtain a reaction mixture;
adding ciprofloxacin HCl and triethylamine to the reaction mixture and stirring with reflux;
cooling the reaction mixture at room temperature to obtain a solid; and
obtaining the 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((5-oxo-2-phenyl-4-(quinolin-2-ylmethylene)-4,5-dihydro-1H-imidazol-1-yl)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid compound.