Patent ID: 11858936
Assignee: DVIR GUR
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A pH-controlled process for preparing synthetic co-crystals of anhydrous guanine and at least one additional material selected from the group consisting of hypoxanthine, xanthine, uric acid, isoguanine, theobromine, isoxanthopterin, xanthopterin, thymine, cytosine, uracil, guanosine, cytidine, thymidine, uridine, adenosine, and inosine, wherein said process comprises the steps of:
preparing a basic or acidic aqueous solution of guanine and the at least one additional material;
maintaining the basic or acidic aqueous solution at a predetermined temperature range for a predetermined period of time;
adjusting the pH of the aqueous solution by adding a base or an acid over a predefined period of time until a predetermined pH value is obtained, thereby providing a synthetic co-crystal suspension comprising co-crystals;
allowing the synthetic co-crystal suspension to mature over a predetermined period of time; and
collecting the synthetic co-crystals from the crystal suspension.