Patent ID: 11903959
Assignee: EMORY UNIVERSITY
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 0:
1. A process for producing a compound, comprising
a) reacting uridine having hydroxyl groups at positions 2′, 3′, and 5′ with a compound to protect or esterify the hydroxyl groups at positions 2′ and 3′ of uridine thereby forming a first intermediate;
b) simultaneously or subsequent to step a), esterifying the hydroxyl group at position 5′ of the first intermediate to form a carboxylic acid ester as a second intermediate;
c) reacting the second intermediate with a 1,2, 4-triazole compound followed by reaction with a hydroxylamine moiety at position 4, thereby forming a third intermediate; and
d) optionally deprotecting the third intermediate.