Patent ID: 11963786
Assignee: UNIVERSITY OF MIAMI
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A

Claim 16:
17. A non-transitory computer-readable medium storing instructions that when executed by one or more processors, cause the one or more processors to:
form a database including a quantification of retinal structure and retinal function of a plurality of eyes associated with a plurality of patients, the quantification providing a baseline cognitive impairment (CI) reference;
receive an electroretinogram (ERG) of a retina of a patient;
determine a measure of functionality of neurons in the retina based on the ERG;
receiving a retinal image of the retina;
skeletonize the retinal image as a skeletonized retinal image;
determine a structural measure of the first retina based on
a generalized dimension spectrum and singularity spectrum of the skeletonized retinal image, and
a lacunarity parameter of the skeletonized retinal image;

comparing the measure of functionality and the structural measure of the retina to the database; and
determine a level of cognitive impairment of the patient based on the comparing.