Patent ID: 11958856
Assignee: JANSSEN PHARMACEUTICA NV
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 2:
3. The compound of claim 1, or a pharmaceutically acceptable salt or stereoisomer thereof, wherein:
R1 is C1-4 fluoroalkyl or 5- or 6-membered heterocyclyl, wherein the 5- or 6-membered heterocyclyl is optionally substituted with one or more independently selected C1-4 fluoroalkyl substituents;
each R2 is independently F or Cl;
R4 is H or F;
R5 is phenyl or 6-membered heteroaryl, wherein the phenyl or 6-membered heteroaryl is optionally substituted with one or two substituents independently selected from the group consisting of halogen, C1-2 hydroxyalkyl, C(O)NRCRD, C(O)OH, NRCRD, and NRCC(O)C1-2 alkyl;
R6 is phenyl or 9- or 10-membered heteroaryl, wherein the phenyl or 9- or 10-membered heteroaryl is optionally substituted with one or two substituents independently selected from the group consisting of halogen, C1-2, fluoroalkyl, C(O)NRERF, and C(O)OH;
each RE is independently H or C1-2 alkyl;
each RF is independently H or C1-2, alkyl; and
a is 1 or 2.