Patent ID: 11884687
Assignee: HOVIONE SCIENTIA LIMITED
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 1:
2. The multifunctional compound as claimed in claim 1, wherein the tripodal boronated core is as defined in claim 1;
R1 represents: H, CH3, C1-C6 alkyl which optionally may incorporate heteroatoms selected from nitrogen, oxygen or sulphur, a polyethylene glycol chain comprising azide, alkyne, alkene or maleimide derived functions, formyl or C2-C6 alkanoyl, CH2Ar or CH2CH2Ar in which the Ar group may be a phenyl, a substituted phenyl ring, a naphthyl, a heteroaromatic ring or fused ring comprising at least one ring heteroatom selected from nitrogen, oxygen or sulphur;
R2 to R5 represents: H, CH3, C1-C6 alkyl which optionally may incorporate heteroatoms selected from nitrogen, oxygen or sulphur, a polyethylene glycol chain comprising azide, alkyne, alkene or maleimide derived functions, formyl or C2-C6 alkanoyl, amide, esters, CH2Ar or CH2CH2Ar in which the Ar group may be a phenyl, a substituted phenyl ring, a naphthyl, a heteroaromatic ring or fused ring comprising at least one ring heteroatom selected from nitrogen, oxygen or sulphur, OH, OCH3, OCH2CH3, OCHCH3CH3, OCH2CHCH3CH3, OPh, CCH, CCPh, CN, COOH, NH2, CONHR′ NHR′ or NR′R″ in which the R′ and R″ groups may be optionally a phenyl or a substituted phenyl, a 5 or 6 member azacyclic ring, CH3, C1-C6 alkyl which optionally may incorporate one further heteroatom selected from oxygen, sulphur or nitrogen;
R6 to R9 represents: H, CH3, C1-C6 alkyl which optionally may incorporate heteroatoms selected from nitrogen, oxygen or sulphur, a polyethylene glycol chain comprising azide, alkyne, alkene or maleimide derived functions, formyl or C2-C6 alkanoyl, amide, esters, CH2Ar or CH2CH2Ar in which the Ar group may be a phenyl, a substituted phenyl ring, a naphthyl, a heteroaromatic ring or fused ring comprising at least one ring heteroatom selected from nitrogen, oxygen or sulphur, OH, OCH3, OCH2CH3, OCHCH3CH3, OCH2CHCH3CH3, OPh, CCH, CCPh, CN, COOH, NH2, CONHR′ NHR′ or NR′R″ in which the R′ and R″ groups may be optionally a phenyl or a substituted phenyl, a 5 or 6 member azacyclic ring, CH3, C1-C6 alkyl which optionally may incorporate one further heteroatom selected from oxygen, sulphur or nitrogen;
R10 represents: H, CH3, C1-C6 alkyl which optionally may incorporate one further heteroatom selected from nitrogen, oxygen or sulphur, a vinyl group of the general formula CH═CHR′ in which the R′ represents a H, CH3, C1-C6 alkyl which optionally may incorporate one further heteroatom selected from oxygen, sulphur or nitrogen, a vinyl group of the general formula CH═CHAr in which the Ar represents a phenyl, a substituted phenyl ring, a heteroaromatic ring comprising at least one ring heteroatom selected from nitrogen, oxygen or sulphur, an Ar in which the Ar group may be a phenyl, a substituted phenyl ring, a Cl-, Br- or F- substituted phenyl ring in the o-, m- or p- positions, a naphthyl, a monocyclic or bicyclic heteroaromatic ring comprising at least one ring heteroatom selected from nitrogen, oxygen or sulphur; and
X and Y represent a heteroatom selected from oxygen or nitrogen.