Patent ID: 11884613
Assignee: CHIROGATE INTERNATIONAL INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The process according to claim 1, wherein the intramolecular cyclization reaction comprises the steps of:
(a) hydrobornation of the compound of Formula 3 with a boron reagent, followed by oxidation with basic hydrogen peroxide to form an alcohol compound of Formula 3′:, wherein P, X, Y, R2 and R3 are as defined in claim 1;

(b) sulfonylation of the compound of Formula 3′ in the presence of a base with a sulfonyl donor to form a compound of Formula 3″:, wherein Z is a sulfonyl group; and P X, Y, R2 and R3 are as defined above; and

(c) intramolecular alkylation of the compound of Formula 3″ in the presence of a base to form the compound of Formula 4.