Patent ID: 11946047
Assignee: TEXAS TECH UNIVERSITY SYSTEM
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 8:
9. A composition comprising of:
inhibitors that decreases an expression of host genes Fosl2, Hcar2, or Cxcl2 and Cxcl3, in an amount sufficient to decrease the virulence or toxicity of a Bacillus anthracis to a host, wherein the inhibitors are RNA molecules active for gene silencing through RNA interference (RNAi) against Fosl2 selected from SEQ ID NO: 32, 34 or 36; against Hcar2 selected from SEQ ID NO:26, 28, or 30; against Cxcl2 selected from SEQ ID NO: 46 and 48; and against Cxcl3 selected from SEQ ID NOS: 50 and 52.