Patent ID: 11896382
Assignee: RETISPEC INC.
Field: Measurement (Instruments)
Classification: CPC A  G | IPC A  G

Claim 19:
20. A non-invasive in vivo ocular light-based detection system comprising:
a first imaging modality;
a second imaging modality; and
one or more processors configured to execute instructions stored in a memory to:
control the first imaging modality to illuminate a wide field-of-view of a fundus of an eye of a subject, and detect light from the eye for determining a first imaging modality information;
determine one or more region of interest (ROI) from the first imaging modality information as being a potential Alzheimer's Disease (AD)-associated pathology based on a detection of one or more biomarkers indicative of AD;
control the second imaging modality to illuminate each of the one or more ROI, and detect light from the eye for determining second imaging modality information; and
classify, using the first imaging modality information and the second imaging modality information, the subject as having one or more AD-associated pathologies, the one or more AD-associated pathologies associated with protein aggregates, the protein aggregates including Tau neurofibrillary tangles.