Patent ID: 11951154
Assignee: FLAGSHIP PIONEERING INNOVATIONS V, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of delivering a therapeutic comprising: administering a composition to a subject, the composition comprising: a polypeptide comprising at least one sequence of ABX″C, wherein A is selected from a hydrophobic amino acid or an amide containing backbone, with a nucleic acid side chain; B and C may be the same or different, and are independently selected from arginine, asparagine, glutamine, lysine, and analogs thereof; X is an amide containing backbone, with a nucleic acid side chain; and n is an integer from 1 to 4; and at least one heterologous moiety, wherein the heterologous moiety is the therapeutic, and wherein the composition increases intracellular delivery of the therapeutic as compared to the therapeutic alone.