Patent ID: 11897922
Assignee: ACCESS TO ADVANCED HEALTH INSTITUTE
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G  Y | IPC A  C  G

Claim 0:
1. A method for stimulating an immune response comprising administering to a subject an effective amount of a composition comprising two or more Mycobacterium tuberculosis antigens, wherein the two or more antigens comprise the antigen Rv3478 comprising the amino acid sequence set forth in SEQ ID NO: 41, the antigen Rv3619 comprising the amino acid sequence set forth in SEQ ID NO:46, the antigen Rv2389 comprising the amino acid sequence set forth in SEQ ID NO: 21, and the antigen Rv1886 comprising the amino acid sequence set forth in SEQ ID NO: 145 or an antigen comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 41, an antigen comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 46, an antigen comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 21, and an antigen comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 145; and wherein the two or more antigens are covalently linked in the form of a fusion polypeptide.