Patent ID: 11939616
Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC A  C

Claim 2:
3. A method for identifying a human cell via its glycosignature comprising the steps of:
(a) providing a population of human cells;
(b) contacting the population of human cells with an α(1,3)-fucosyltransferase VI;
(c) detecting fucosylated lactosaminyl glycans Lex, sLex, VIM-2, and Di-Fuc-sLex on the population of human cells of step (b); and
(d) identifying the population of human cells detected in step (c) having an enforced fucosylated lactosaminyl glycan pattern selected from the group consisting of:
(i) sLex (+)>>Lex(+), with Di-Fuc-sLex (+), and VIM-2 (−); and
(ii) Lex(+), sLex (−), VIM-2 (−), and Di-Fuc-sLex (−).