Patent ID: 11959840
Assignee: VENTANA MEDICAL SYSTEMS, INC.
Field: Measurement (Instruments)
Classification: CPC G | IPC G

Claim 13:
14. A method of fixing a tissue sample comprising a diffusion step and a cross-linking step:
(a) wherein the diffusion step comprises immersing the tissue sample in a fixative at a first temperature ranging from between about −20° C. to about 15° C., and permitting the fixative to diffuse into the tissue sample for a first time period to obtain a fixative-diffused tissue sample; and
(b) wherein the cross-linking step comprises actively or passively heating the fixative to a second temperature ranging from between about 20° C. to about 55° C. for a second time period to permit cross-linking,
wherein at least one of the first or second time periods is a processing protocol derived from time-of-flight data for one or more of: (i) a tissue type that is a same type as the tissue sample; (ii) a tissue shape that is similar in shape to the tissue sample; or (iii) a tissue size that is similar in size to the tissue sample.