Patent ID: 11951123
Assignee: PLATFORM OPHTHALMIC INNOVATIONS, LLC
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. An ophthalmic pharmaceutical formulation, comprising:
a. povidone with a concentration in the range of between about 1% and about 3% (w/w);
b. a mucoadhesive polymer selected from the group consisting of hyaluronic acid and salts thereof and carbomer, and combinations thereof;
c. poloxamer 407;
d. a surfactant selected from the group consisting of polyoxyl 35 castor oil and polyoxyl 40 hydrogenated castor oil, and combinations thereof;
e. ascorbic acid or a derivative thereof with an ascorbic acid equivalent concentration of about 0.03% (w/w) and trisodium citrate with a concentration of about 0.55% (w/w);
f. a tonicity agent selected from the group consisting of mannitol, sorbitol, and dextrose, and combinations thereof, in a total amount of up to about 5% (w/w); and
g. one or more osmoprotectants selected from the group consisting of proline, betaine, taurine, trehalose, and glutamic acid, and combinations thereof, in a total amount up to about 5% (w/w);
wherein the ophthalmic pharmaceutical formulation is preservative-free.