Patent ID: 11959141
Assignee: FOUNDATION MEDICINE, INC.
Field: Computer technology (Electrical engineering)
Classification: CPC C  G | IPC C  G

Claim 13:
14. The method of claim 1, wherein the expressed subgenomic interval comprises a sequence encoding an antibody; an antibody light chain; an antibody heavy chain; a variable region; a heavy chain variable region; a light chain variable region; a constant region; a heavy chain constant region; a light chain constant region; a kappa light chain sequence; a lambda light chain sequence; a portion of a constant region that can distinguish one or more Ig classes or subclasses; a CDR; a light chain CDR1; a light chain CDR2; a light chain CDR3; a heavy chain CDR1; a heavy chain CDR2; a heavy chain CDR3; a T cell receptor; an alpha chain of a T cell receptor; a beta chain of a T cell receptor; a delta chain of a T cell receptor; a gamma chain of a T cell receptor; a sequence encoding an antibody variable region; a sequence encoding a B cell receptor variable region; a sequence encoding a T cell receptor variable region; a sequence encoding an antibody diversity region; a sequence encoding a B cell receptor diversity region; a sequence encoding a T cell receptor diversity region; a sequence encoding an antibody joining region; a sequence encoding a B cell receptor joining region; a sequence encoding a T cell receptor joining region; a sequence encoding an antibody switch region; a sequence encoding a B cell receptor switch region; a sequence encoding a T cell receptor switch region; a sequence encoding an antibody constant region; a sequence encoding a B cell receptor constant region; a sequence encoding a T cell receptor constant region; a sequence encoding a V segment, prior to rearrangement, of an antibody; a sequence encoding a V segment, prior to rearrangement, of an Ig superfamily-receptor; a sequence encoding a V segment, prior to rearrangement, of an immunoglobulin gene; a sequence encoding a V segment, prior to rearrangement, of a T cell receptor; a sequence encoding a V segment, prior to rearrangement, of a B cell receptor; a sequence encoding a V segment, after rearrangement, of an antibody; a sequence encoding a V segment, after rearrangement, of an Ig superfamily-receptor; a sequence encoding a V segment, after rearrangement, of an immunoglobulin gene; a sequence encoding a V segment, after rearrangement, of a T cell receptor; a sequence encoding a V segment, after rearrangement, of a B cell receptor; a sequence encoding a D segment, prior to rearrangement, of an antibody; a sequence encoding a D segment, prior to rearrangement, of an Ig superfamily-receptor; a sequence encoding a D segment, prior to rearrangement, of an immunoglobulin gene; a sequence encoding a D segment, prior to rearrangement, of a T cell receptor; a sequence encoding a D segment, prior to rearrangement, of a B cell receptor; a sequence encoding a D segment, after rearrangement, of an antibody; a sequence encoding a D segment, after rearrangement, of an Ig superfamily-receptor; a sequence encoding a D segment, after rearrangement, of an immunoglobulin gene; a sequence encoding a D segment, after rearrangement, of a T cell receptor; a sequence encoding a D segment, after rearrangement, of a B cell receptor; a sequence encoding a J segment, prior to rearrangement, of an antibody; a sequence encoding a J segment, prior to rearrangement, of an Ig superfamily-receptor; a sequence encoding a J segment, prior to rearrangement, of an immunoglobulin gene; a sequence encoding a J segment, prior to rearrangement, of a T cell receptor; a sequence encoding a J segment, prior to rearrangement, of a B cell receptor; a sequence encoding a J segment, after rearrangement, of an antibody; a sequence encoding a J segment, after rearrangement, of an Ig superfamily-receptor; a sequence encoding a J segment, after rearrangement, of an immunoglobulin gene; a sequence encoding a J segment, after rearrangement, of a T cell receptor; a sequence encoding a J segment, after rearrangement, of a B cell receptor; a sequence encoding V, D, and J segments, prior to rearrangement, of an antibody; a sequence encoding V, D, and J segments, prior to rearrangement, of an Ig superfamily-receptor; a sequence encoding V, D, and J segments, prior to rearrangement, of an immunoglobulin gene; a sequence encoding V, D, and J segments, prior to rearrangement, of a T cell receptor; a sequence encoding V, D, and J segments, prior to rearrangement, of a B cell receptor; a sequence encoding V, D, and J segments, after rearrangement, of an antibody; a sequence encoding V, D, and J segments, after rearrangement, of an Ig superfamily-receptor; a sequence encoding V, D, and J segments, after rearrangement, of an immunoglobulin gene; a sequence encoding V, D, and J segments, after rearrangement, of a T cell receptor; a sequence encoding V, D, and J segments, after rearrangement, of a B cell receptor; a sequence encoding V and J segments, prior to rearrangement, of an antibody; a sequence encoding V and J segments, prior to rearrangement, of an Ig superfamily-receptor; a sequence encoding V and J segments, prior to rearrangement, of an immunoglobulin gene; a sequence encoding V and J segments, prior to rearrangement, of a T cell receptor; a sequence encoding V and J segments, prior to rearrangement, of a B cell receptor; a sequence encoding V and J segments, after rearrangement, of an antibody; a sequence encoding V and J segments, after rearrangement, of an Ig superfamily-receptor; a sequence encoding V and J segments, after rearrangement, of an immunoglobulin gene; a sequence encoding V and J segments, after rearrangement, of a T cell receptor; a sequence encoding V and J segments, after rearrangement, of a B cell receptor; a sequence comprising a VD junction of an Ig superfamily receptor; a sequence comprising a VD junction of an immunoglobulin gene; a sequence comprising a VD junction of a T cell receptor; a sequence comprising a VD junction of a B cell receptor; a sequence comprising a DJ junction of an Ig superfamily receptor; a sequence comprising a DJ junction of an immunoglobulin gene; a sequence comprising a DJ junction of a T cell receptor; a sequence comprising a DJ junction of a B cell receptor; a sequence comprising a VJ junction of an Ig superfamily receptor; a sequence comprising a VJ junction of an immunoglobulin gene; a sequence comprising a VJ junction of a T cell receptor; or a sequence comprising a VJ junction of a B cell receptor.