Patent ID: 11873482
Assignee: 10X GENOMICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 24:
25. The method of claim 1, further comprising processing a protein analyte in the biological sample, wherein the processing comprises:
before step (d), contacting the biological sample with a plurality of analyte capture agents, wherein an analyte capture agent of the plurality of analyte capture agents comprises i) an analyte binding moiety, and ii) a capture agent barcode domain, wherein the analyte binding moiety specifically binds to the protein analyte, and wherein the capture agent barcode domain comprises an analyte binding moiety barcode that identifies the analyte binding moiety and a capture handle sequence; and
hybridizing the capture agent barcode domain, via the capture handle sequence, to a second capture domain of a second capture probe comprised in the array, wherein the second capture probe further comprises a second spatial barcode.