Patent ID: 11891401
Assignee: NOVARTIS AG
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 13:
14. A process for preparing a co-crystal according to claim 1, comprising (1) adding fumaric acid to a first solvent to form a fumaric acid solution; (2) adding N-(4-fluoro-3-(6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl) phenyl)-2,4-dimethyloxazole-5-carboxamide to a second solvent to form a N-(4-fluoro-3-(6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl) phenyl)-2,4-dimethyloxazole-5-carboxamide solution; and
(3) adding said fumaric acid solution to said N-(4-fluoro-3-(6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl) phenyl)-2,4-dimethyloxazole-5-carboxamide solution to form said N-(4-fluoro-3-(6-(3-methylpyridin-2-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)phenyl)-2,4-dimethyloxazole-5-carboxamide fumaric acid co-crystal.