Patent ID: 11944102
Assignee: STELLENBOSCH UNIVERSITY
Field: Biotechnology (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 10:
11. A method for controlling pest infestation, the method comprising:
(a) introducing an siRNA molecule targeting the mature mRNA of D. noxia cprr1-8 in a region between nucleotides 464 and 774 of SEQ ID NO: 23, into a plant or transforming the plant with a polynucleotide which causes the plant to express the siRNA molecule wherein the siRNA molecule includes a polynucleotide comprising an RNA sequence which is complementary to at least 19 contiguous nucleotides in the region between nucleotides 464 and 774 and the siRNA is capable of silencing the cprr1-8 gene; and
(b) providing the plant, or portion thereof, to the pest;
(c) wherein pests to which the siRNA have been administered have reduced virulence.