Patent ID: 11911471
Assignee: HEMANEXT INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 0:
1. A method for reducing microparticle formation in a whole blood product comprising:
reducing oxygen from whole blood to prepare an oxygen reduced whole blood product having an oxygen saturation (SO2) of less than 25%;
reducing blood pathogens from the oxygen reduced whole blood product comprising:
adding riboflavin to a concentration of between 40 and 60 micromolar (μM); and
irradiating the riboflavin containing whole blood product with UV light between 265 and 400 nanometers (nm), thereby obtaining an oxygen reduced pathogen reduced whole blood product,
wherein said microparticles are reduced by between 20 and 60% relative to a whole blood product from which blood pathogens are reduced and oxygen is not reduced.