Patent ID: 11908560
Assignee: ONCOHOST LTD.
Field: Medical technology (Instruments)
Classification: CPC G | IPC G

Claim 14:
15. The method of claim 13, wherein said predicting the response to said immunotherapy comprises:
a. receiving a plurality of protein data element values
i. in a population of subjects suffering from cancer and known to respond to said immunotherapy (responders); and
ii. in a population of subjects suffering from cancer and known to not respond to said therapy (non-responders);

b. calculating for proteins of said plurality of protein data element values a resistance score, where said resistance score is based on the similarity of said protein data element value in said subject to the protein data element value in said responders and the similarity of said protein data element value in said subject to said non-responders; and
c. classifying a protein of said plurality of protein data element values with a resistance score beyond a predetermined threshold as a resistance-associated protein;
wherein a subject with a number of resistance-associated proteins above a predetermined number is predicted to be resistant to said therapy and a subject with a number of resistance-associated factors at or below a predetermined number is predicted to respond to said therapy.