Patent ID: 11873489
Assignee: SILENCE THERAPEUTICS GMBH
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 1:
2. The nucleic acid of claim 1, wherein the nucleic acid is conjugated to a ligand comprising a compound of formula (I):

[S—X1—P—X2]3-A-X3—  (I)

wherein:
S represents a saccharide;
X1 represents C3-C6 alkylene or (—CH2—CH2—O)m(—CH2)2— wherein m is 1, 2, or 3;
P is a phosphate or modified phosphate;
X2 is alkylene or an alkylene ether of the formula (—CH2)n-O—CH2— where n=1-6;
A is a branching unit;
X3 represents a bridging unit;
wherein a nucleic acid as defined in claim 1 is conjugated to X3 via a phosphate or modified phosphate.