Patent ID: 11965039
Assignee: ZP SPV 3 K/S
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 23:
24. A compstatin analogue according to claim 1 which comprises a lipophilic group ϕ, and wherein the lipophilic group ϕ is Z1— or Z1—Z2—; wherein
Z1 is A-C12-22alkylene-(CO)—;
where A is H or —COOH, and wherein the alkylene may be linear or branched and may be saturated or unsaturated, and may optionally incorporate a phenylene or piperazinylene moiety in its length; and
Z2 is a sequence of 1 to 6 residues of compounds selected from γ-Glu, E, K, Orn, S, T, A, β-Ala, G, P, V, L, I, Y, Q, N, Dapa, Gaba, or Aib, or a corresponding D form thereof, 5-aminopentanoyl, 6-aminohexanoyl, 7-aminoheptanoyl, 8-aminooctanoyl, 9-aminononanoyl, and 10-aminodecanoyl, 8-amino-3,6-dioxaoctanoic acid (Peg3), 11-amino-3,6,9-trioxaundecanoic acid (Peg4) and (piperazine-1-yl)-carboxylic acid.