Patent ID: 11926861
Assignee: HEIDI KAY
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A method for determining treatment of an HIV-infected subject, the method comprising:
(a) obtaining whole blood from an HIV-infected subject, wherein the whole blood comprises latently-infected cells;
(b) contacting the whole blood with a supportive medium and at least one virus stimulant and/or at least one virus inhibitor, thereby providing an admixture;
(c) incubating the admixture for a period of time so as to induce virus production from the whole blood;
(d) detecting in the incubated admixture the presence or absence of at least one of an HIV virus particle, an HIV viral nucleic acid, an HIV viral polypeptide, an HIV viral genomic sequence, infectivity, or a combination thereof,
wherein the detecting further comprises comparing the presence or absence of at least one molecule in the admixture to the presence or absence of at least one molecule in a control sample, thereby identifying subject responsiveness to the stimulant and/or inhibitor, and
(e) treating the subject with the at least one virus stimulant and/or at least one virus inhibitor.