Patent ID: 11944594
Assignee: MURRAY AND POOLE ENTERPRISES LTD
Field: Pharmaceuticals (Chemistry)
Classification: CPC A | IPC A

Claim 23:
24. A method for reducing a risk of at least one cardiovascular event in a subject in need thereof, which comprises:
administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), and
continuing orally administering to the subject the composition once per day for a duration ranging from 24 months to 44 months;
wherein the at least one cardiovascular event is chosen from myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death;
wherein the subject has no contra-indications to colchicine therapy, and has at least one risk factor chosen from:
i. an age greater than or equal to 35;
ii. diabetes;
iii. past myocardial infarction;
iv. unstable angina;
v. coronary bypass surgery;
vi. coronary angioplasty; and
vii. therapy with at least one drug chosen from aspirin, clopidogrel, statins, beta blockers, calcium blockers, and ACE inhibitors; and, wherein the composition reduces the risk of the subject experiencing the at least one cardiovascular event by a greater percentage than a composition that does not include colchicine or a pharmaceutically acceptable salt thereof.