Patent ID: 11878970
Assignee: PETRA PHARMA CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 59:
60. The compound of claim 59, or pharmaceutically acceptable salt thereof, wherein R1 is a group of the formula:, R2 is an optionally substituted bicyclic ring selected from 1,3-benzodioxole, 2,3-dihydro-1,4-benzodioxine, isoindolin-1-one, indoline-2-one, or benzo[d]oxazol-2(3H)-one, or an optionally substituted bicyclic heteroaryl wherein a phenyl, pyridine, pyrazine, pyrimidine, or pyridazine ring is fused to a pyrrole, furan, thiophene, pyrazole, isoxazole, imidazole, oxazole, thiazole, triazole, pyridine, pyrazine, pyrimidine, or pyridazine ring; wherein the optionally substituted bicyclic ring is optionally substituted with one to three substituents each independently selected from C1-C6 alkyl; the optionally substituted bicyclic heteroaryl is optionally substituted with one to three substituents each independently selected from -CN, halogen, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, an optionally substituted C1-C6 alkyl, an optionally substituted C3-C5 cycloalkyl, an optionally substituted heterocycle selected from pyrrolidine, pyrrolidinone, piperidine or morpholine, an optionally substituted phenyl, or an optionally substituted heteroaryl selected from pyrazole, isoxazole, isothiazole, imidazole, oxazole, or thiazole; wherein the optionally substituted C1-C6 alkyl is optionally substituted with a —CN, —OH, or C1-C3 alkoxy; the optionally substituted C3-C5 cycloalkyl, phenyl, heterocycle or heteroaryl is each optionally substituted with one to three substituents each independently selected from halogen, C1-C3 alkyl, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, —NR10R10, —OH or —CN;
R3 is —H, —CN, C1-C3 alkyl, or C1-C3 haloalkyl;
R4 is —H, or halogen;
R5 is —H, halogen, C1-C3 alkyl or C1-C3 haloalkyl;
R6 is —H, or halogen;
R7 is —CN, methyl or trifluoromethyl;
R is —H;
each R9 is independently —H, halogen, methyl, C1-C3 haloalkyl, or cyclopropyl; and
each R10 is independently —H or C1-C3 alkyl.