Patent ID: 11951278
Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 18:
19. A non-transitory computer-readable storage medium having stored therein computer-executable instructions that when executed cause at least one processor to:
track, via an insulin on board estimator module and in real time, insulin on board (IOB) of a patient, IOB being an amount of insulin active and/or an amount of insulin to be active in the patient;
receive feed-forward signals and calculate, via a monitoring module and Kalman filtering, an amount of insulin need of the patient, wherein the amount of insulin need of the patient is calculated by insulin that should be on board (ISOB)-IOB, wherein the ISOB is based on an estimation or a prediction of patient glucose level;
compare, via a fault detection and classification module, the amount of insulin active in the patient and/or the amount of insulin to be active in the patient with the amount of insulin need of the patient;
determine, via the fault detection and classification module, an insulin fault level based on the comparison; and
automatically change, via a remediation module and in response to determining the fault level, insulin delivery by an insulin delivery device such that the amount of insulin active in the patient approaches the amount of insulin need of the patient.