Patent ID: 11857288
Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Field: Medical technology (Instruments)
Classification: CPC A  G | IPC A  G

Claim 0:
1. A method of strain analysis of a cardiac region of interest of a subject from displacement encoded magnetic resonance image (MRI) data, the method comprising:
acquiring displacement encoded MRI data corresponding to the cardiac region of interest of the subject;
generating a phase image for each frame of the displacement encoded MRI data, wherein the phase image comprises potentially phase-wrapped measured phase values corresponding to pixels of the frame;
training a convolutional neural network (CNN) to compute a wrapping label map for the phase image, wherein the wrapping label map comprises a number of phase wrap cycles present at each pixel in the phase image;
computing, by the trained CNN, the wrapping label map;
computing an unwrapped phase image by adding a respective phase correction to each of the potentially phase-wrapped measured phase values of the phase image, wherein the phase correction is based on the number of phase wrap cycles present at each pixel; and
computing myocardial strain using the unwrapped phase image for strain analysis of the subject.