Patent ID: 11952374
Assignee: ALIGOS THERAPEUTICS, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A compound of Formula (I), or a pharmaceutically acceptable salt thereof, having the structure:, wherein:
n is 1;
Z1 is —C(═O)—;
R1 is selected from the group consisting of, R2 and R3 are independently selected from the group consisting of hydrogen and an unsubstituted C1-4 alkyl;
R4, R5, R6 and R7 are each hydrogen;
R8 is selected from the group consisting of an optionally substituted monocyclic heteroaryl and —NR14AR14B;
R9 is a substituted phenyl, a substituted monocyclic heteroaryl or a substituted fused-bicyclic heteroaryl, wherein the substituted phenyl, the substituted monocyclic heteroaryl or the substituted fused-bicyclic heteroaryl is substituted with one or more substituents selected from the group consisting of halogen, an unsubstituted C1-4 alkyl, an unsubstituted C1-4 haloalkyl, an unsubstituted C1-4 alkoxy, an optionally substituted monocyclic heteroaryl, an optionally substituted monocyclic heterocyclyl, amino, a mono-substituted amine, a di-substituted amine and —C(═O)NHR15;
R14A is a monocyclic C3-6 cycloalkyl optionally substituted with one or two halogens, a monocyclic C3-6 cycloalkyl(C1-4 alkyl) optionally substituted with one or two halogens, an optionally substituted 4-6 member monocyclic heterocyclyl or an optionally substituted monocyclic 4- to 6-membered heterocyclyl(C1-4 alkyl);
R14B is selected from the group consisting of an optionally substituted aryl and an optionally substituted aryl(C1-4 alkyl); and
R15 is hydrogen, an unsubstituted C1-6 alkyl, an optionally substituted C2-6 alkenyl, an optionally substituted C1-6 alkynyl or an optionally substituted C3-6 monocyclic cycloalkyl.