Patent ID: 11959105
Assignee: QUANTUM-SI INCORPORATED
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 2:
3. The modified recombinant DNA polymerase of claim 2, wherein the amino acid sequence of the modified recombinant DNA polymerase comprises a modification at one or more positions corresponding to E139, E142, N145, 1148, D167, D171, D189, N467, E482, D492, K495, D521, and E523, wherein optionally, the modification is an amino acid substitution selected from the group consisting of: E139K, E139Q, E139R, E139H, E142K, E142H, E142R, E142Q, N145K, N145H, N145R, I148K, I148H, I148R, D167P, D167K, D167H, D167R, D171K, D171H, D171R, D189K, D189H, D189R, N467R, N467K, N467H, N467S, N467T, E482K, E482H, E482R, D492H, D492K, D492R, K495R, D521K, D521H, D521R, E523K, E523Y, E523H, E523R, E523F, and E523W.