Patent ID: 11898142
Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Field: Measurement (Instruments)
Classification: CPC C  B  G  Y | IPC B  C  G

Claim 14:
15. The system of claim 10, wherein the one or more RNA-based masking constructs comprises an RNA oligonucleotide to which a detectable ligand and a masking component are attached; or
wherein the one or more RNA-based masking constructs comprises a nanoparticle held in aggregate by bridge molecules, wherein at least a portion of the bridge molecules comprises RNA, wherein the solution undergoes a color shift when the nanoparticle is disbursed in solution; wherein the nanoparticle is optionally a colloidal metal such as colloidal gold; or
wherein the detectable ligand is a fluorophore and the masking component is a quencher molecule.