Patent ID: 11904581
Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Field: Surface technology, coating (Chemistry)
Classification: CPC B | IPC B

Claim 0:
1. A bifunctional film, comprising:
an anti-adhesion layer; and
an attachment layer over the anti-adhesion layer,
wherein the anti-adhesion layer comprises a first polymer mixture, and the first polymer mixture comprises:
a first hydrophobic polymer which is at least one hydrophobic polymer selected from the group consisting of: polycaprolactone (PCL), polylactic acid (PLA), poly(lactic-co-glycolic acid) (PLGA), poly(glycolic acid) (PGA), polyhydroxybutyrate (PHB), polydioxanone (PDS), poly(propylene fumarate) (PPF), polyanhydrides, polyacetals, poly(ortho esters), polycarbonates, polyurethanes, polyphosphazenes and polyphosphoester; and
a first hydrophilic polymer which is at least one hydrophilic polymer selected from the group consisting of: hyaluronic acid (HA), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), polyethylene glycol (PEG), a derivative of polyethylene glycol and poly(ethylene oxide) (PEO), and

in the anti-adhesion layer, a weight ratio of the first hydrophobic polymer to the first hydrophilic polymer is 1:0.01-1,
wherein the anti-adhesion layer is formed by a step of drying a first polymer solution to form a film, and the first polymer solution comprises a first hydrophobic solution and a first hydrophilic solution, and the solute of the first hydrophobic solution is the first hydrophobic polymer, and the solute of the first hydrophilic solution is the first hydrophilic polymer,
wherein the attachment layer consists of a second hydrophilic polymer, and the second hydrophilic polymer is at least one hydrophilic polymer selected from the group consisting of: gelatin, a modified gelatin, alginate, polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), polyethylene glycol (PEG), a derivative of polyethylene glycol, collagen, demineralized bone matrix (DBM), bone morphogenetic protein (BMP), albumin, chitosan, fibrin, polyoxyethylene and polyvinylpyrrolidone, and
wherein the attachment layer is formed by a step of drying a second polymer solution over the anti-adhesion layer to form a film, and the second polymer solution consists of a second hydrophilic solution, and the solute of the second hydrophilic solution is the second hydrophilic polymer.