Patent ID: 11932640
Assignee: KING FAISAL UNIVERSITY
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 2:
3. A method of treating a bacterial infection in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound, wherein the compound has the formula I:, , or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
R1 is methyl;
R2 is fluorine;
R3 is hydrogen, hydroxy, NHR7, or NR7R8 where R7 and R8 are independently—C2H4N(CH3)2, methoxyphenyl, or aminopropyl, or where R7 and R8 are taken together with the nitrogen to which they are attached to form a methylpiperazine; and
R4 and R5 are independently a hydrogen atom, —COR9 where R9 is a hydroxy group, or a methylamino group substituted with a methyl and a cyclohexyl group or a pentyl group;, wherein the bacterial infection is caused by Gram-positive Staphylococcus aureus, Staphylococcus aureus resistant to MRSA, Staphylococcus epidermidis, Bacillus subtilis, Enterococcus faecium, Enterococcus faecium resistant to VRE, or Gram-negative Klebsiella pneumonia, Escherichia coli, or Pseudomonas aeruginosa.