Patent ID: 11926843
Assignee: LIFEEDIT THERAPEUTICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 7:
8. A system, said system comprising:
a) one or more guide RNAs (gRNAs), or one or more nucleotide sequences encoding the one or more gRNAs; and
b) an RNA-guided nuclease (RGN) polypeptide comprising an amino acid sequence:
(i) having at least 95% sequence identity to any one of SEQ ID NOs: 11, 27, 45, or 54;
(ii) having at least 98% sequence identity to SEQ ID NOs: 1 or 19; or
(iii) set forth as SEQ ID NO: 36, or

a nucleotide sequence encoding the RGN polypeptide;, wherein said nucleotide sequences encoding the one or more gRNAs and encoding the RGN polypeptide are each operably linked to a promoter heterologous to each said nucleotide sequence.