Patent ID: 11940449
Assignee: ID-FISH TECHNOLOGY, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC G  A  C | IPC A  C  G

Claim 3:
4. A method for detecting IgM-class or IgA-class antibodies resulting from infection by a coronavirus, if present in a biological sample obtained from a subject suspected of having a coronavirus infection, the method comprising:
a) providing a composition comprising at least four labelled and/or tagged and/or bound amino acid sequences, wherein the at least four labelled and/or tagged and/or bound amino acid sequences comprise amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4, and variants thereof which retain the immunological binding profile of the corresponding non-variant;
b) providing the biological sample obtained from the subject suspected of having a coronavirus infection;
c) contacting the biological sample with the composition of step a) under conditions appropriate for specific antibody binding to an epitope; and
d) detecting specific binding of IgM-class or IgA-class antibodies with the amino acid sequences of step a), wherein the sample is scored as positive for coronavirus infection when at least two of the amino acid sequences of step a) exhibit positive binding with IgM-class or IgA-class antibodies from the biological sample.