Patent ID: 11926592
Assignee: AMGEN INC.
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC C

Claim 0:
1. An omecamtiv mecarbil fumarate crystalline salt form which is any one of the following forms:
i) an omecamtiv mecarbil bis-fumarate crystalline salt form A, characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 5.64, 15.76, 22.03, and 23.87±0.2° 2θ using Cu Kα radiation;
ii) an omecamtiv mecarbil bis-fumarate crystalline salt form B, characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 5.68, 6.11, 13.13, 18.08, and 22.47±0.2° 2θ using Cu Kα radiation;
iii) an omecamtiv mecarbil bis-fumarate crystalline salt form C, characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 5.88, 18.79, 25.41, and 26.86±0.2° 2θ using Cu Kα radiation; or
iv) an omecamtiv mecarbil mono-fumarate crystalline salt form D, characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 8.01, 15.20, and 20.02±0.2° 2θ using Cu Kα radiation.