Patent ID: 11931420
Assignee: CELGENE CORPORATION
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 20:
21. A kit comprising:
a) one or more doses of an antibody conjugate according to the formula:, wherein n is from 1 to 4;
the antibody comprises a VH region of SEQ ID NO: 13, and a VL region of SEQ ID NO: 14;
the antibody further comprises a constant region domain that comprises a residue of p-azidomethyl-phenylalanine substituting at each of sites HC-F404 and HC-Y180 according to the EU numbering scheme; and
each structure within the brackets of the formula is bonded to the antibody at one of the p-azidomethyl-phenylalanine residues, and
b) one or more doses of a gamma secretase inhibitor, according to the formula:, or a pharmaceutically acceptable salt, clathrate, solid form, solvate, stereoisomer, tautomer or racemic mixture thereof,
and instructions for use of the antibody conjugate and the gamma secretase inhibitor.