Patent ID: 11866742
Assignee: DENALI THERAPEUTICS INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 4:
5. The method of claim 1, wherein the sequence having at least 90% identity to SEQ ID NO: 151 has at the following positions with reference to SEQ ID NO: 151:
a. Trp, Leu, or Glu at position 150;
b. Tyr at position 154;
c. Thr at position 156;
d. Glu at position 157;
e. Trp at position 158;
f. Ser or Ala at position 159;
g. Ser or Asn at position 160;
h. Thr at position 183;
i. Glu at position 185;
j. Glu at position 186; and
k. Phe at position 191.