Patent ID: 11958861
Assignee: INCYTE CORPORATION
Field: Organic fine chemistry (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 36:
37. The compound of claim 1, or a pharmaceutically acceptable salt thereof, wherein R3 is selected from phenyl, cyclopropyl, cyclohexenyl, pyrazolyl, pyrrolyl, 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridinyl, 6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazinyl, 3,4-dihydro-2H-benzo[b][1,4]oxazinyl, 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazolyl, and pyrazolo[1,5-a]pyrimidinyl, wherein the phenyl, cyclopropyl, cyclohexenyl, pyrazolyl, pyrrolyl, 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridinyl, 6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazinyl, 3,4-dihydro-2H-benzo[b][1,4]oxazinyl, 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazolyl, and pyrazolo[1,5-a]pyrimidinyl of R3 are each optionally substituted with 1, 2, 3, or 4 independently selected R3A substituents; and
each R3A is independently selected from methyl, —CD3, ethyl, isopropyl, isobutyl, difluoroethyl, trifluoroethyl, methoxy, cyclopropyl, cyclopentyl, piperidinyl, tetrahydrofuranyl, tetrahydropyranyl, cyclopropylmethyl, cyclopropylethyl, phenylmethyl, pyridylmethyl, piperidinylmethyl, morpholinylmethyl, morpholinylethyl, morpholinylcarbonyl, dimethylaminocarbonyl, and ethylsulfonyl, wherein the methyl, ethyl, isopropyl, isobutyl, cyclopropyl, cyclopentyl, piperidinyl, tetrahydrofuranyl, tetrahydropyranyl, cyclopropylmethyl, cyclopropylethyl, phenylmethyl, pyridylmethyl, piperidinylmethyl, morpholinylmethyl, and morpholinylethyl of R3A are each optionally substituted with 1 or 2 substituents independently selected from hydroxy, methoxy, methylsulfonyl, methylcarbonyl, and cyano.