Patent ID: 11865535
Assignee: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Field: Chemical engineering (Chemistry)
Classification: CPC B | IPC B

Claim 15:
16. A method of making the microfluidic reaction system of claim 1, the method comprising:
forming a microfluidic volume in a microfluidic die;
forming a proud structure rising from a floor of the microfluidic volume;
introducing a reaction agent into the microfluidic volume; and
freeze-drying the reaction agent within the microfluidic volume to coat external surfaces of the proud structure that face the microfluidic volume, the freeze-drying comprising:
freezing the reaction agent during a first freezing period; and
drying the reaction agent during two drying periods, a first drying period having a lower temperature than a second drying period.