Patent ID: 11865216
Assignee: ARON H. BLAESI
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A

Claim 35:
36. A pharmaceutical dosage form comprising:
a drug-containing solid having an outer surface and an internal three dimensional structural framework of one or more thin structural elements with average element thickness in the range of 2.5 μm to 2 mm, said framework contiguous with and terminating at said outer surface;
said thin structural elements comprising at least an active pharmaceutical ingredient, at least 15 weight percent of one or more absorptive polymeric excipients being mutually soluble with a physiological fluid and having a molecular weight in the range between 2 kg/mol and 500 kg/mol, and at least a hydrophilic surface composition;
said thin structural elements further having segments spaced apart from adjoining segments, thereby defining free spaces, wherein a plurality of adjacent free spaces combine across the drug-containing solid to define one or more interconnected free spaces forming an open pore network;
wherein
upon immersion in a physiological fluid said open pore network enables uniform wetting of the structural framework, and the physiological fluid penetrates into the thin fibers, so that the drug-containing solid expands in all dimensions and transitions to a viscous medium.