Patent ID: 11866441
Assignee: THE BROAD INSTITUTE, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  Y | IPC A  C

Claim 0:
1. A compound having the structure:, R1 is optionally substituted aryl or heteroaryl;
R2 is optionally substituted alkoxy, cycloalkoxy or heterocyclyl;
R3 is hydrogen, or —CH2—X;
R4 and R5 are independently hydrogen, —X, or —CH2—X, and at least one of R4 and R5 is not hydrogen;
—X is independently selected at each occurrence from —OH, —OR, —S(O)R, —S(O)2R, —N(R)—S(O)2R, —S(O)2—N(R)(R), —S(O)2—NHR, —N(R)—C(O)—R, —NH2, or —N(R)(R); and
R is independently at each occurrence an optionally substituted C1-C12 alkyl;
or a pharmaceutically acceptable salt thereof.