Patent ID: 11872217
Assignee: CHEMOCENTRYX, INC.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C  Y | IPC A  C

Claim 4:
5. A compound of Formula (II),, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, wherein:
Y′ is O or NH,
each R2a and R2a′ is independently selected from the group consisting of H, methyl, Cl, F, and —O-methyl;
R3 and R3′ are each independently selected from the group consisting of —NRdRe and 4- to 9-membered monocyclic or spirocyclic non-aromatic heterocyclic rings, wherein the 4- to 9-membered monocyclic or spirocyclic non-aromatic heterocyclic rings contain from 1 to 3 N heteroatoms and are optionally substituted with from 1 to 2 substituents independently selected from the group consisting of —OH and —OC(O)Rg;
Rd is selected from the group consisting of H and C1-8 alkyl;
Re is selected from —C1-8 alkyl and —C1-6 alkylene-SO3Rg, wherein the alkyl or alkylene portions of Re are optionally further substituted with from 1 to 2 substituents independently selected from OH, COOH, and COO—C1-8 alkyl;
each Rg is independently selected from H and C1-8 alkyl optionally substituted with 1 to 2 NH2;
R4 and R4′ are each independently selected from the group consisting of H and −O-ethyl;
m is 0 or 1; and
R6b′ is F.