Patent ID: 11926843
Assignee: LIFEEDIT THERAPEUTICS, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 20:
21. The nucleic acid molecule of claim 20, wherein said target DNA sequence is located adjacent to a protospacer adjacent motif (PAM) site of:
(a) NNNNCC (SEQ ID NO: 6), wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 11;
(b) NNRNCC (SEQ ID NO: 32), wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 27;
(c) NNRAATY (SEQ ID NO: 50), wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 45;
(d) NNRNNC (SEQ ID NO: 59), wherein the RGN polypeptide comprises an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 54;
(e) NNNNCC (SEQ ID NO: 6), wherein the RGN polypeptide comprises an amino acid sequence having at least 98% sequence identity to SEQ ID NO: 1;
(f) NNNNCC (SEQ ID NO: 6), wherein the RGN polypeptide comprises an amino acid sequence having at least 98% sequence identity to SEQ ID NO: 19; or
(g) NGG (SEQ ID NO: 41), wherein the RGN polypeptide comprises an amino acid sequence set forth as SEQ ID NO: 36.