Patent ID: 11926824
Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A  G  Y | IPC A  C  G

Claim 0:
1. A method of treating a subject having breast cancer, the method comprising:
(a) obtaining a biological sample from the subject;
(b) measuring the level of Dicer in an exosomal fraction of the sample, wherein the exosomal fraction comprises exosomes that contain TSG101;
(c) identifying the subject as having or not having a breast cancer biomarker based on the measured level of Dicer, wherein if the measured level of Dicer is increased relative to a reference level, then the patient is identified as having the breast cancer biomarker;
(d) selecting a subject identified as having the breast cancer biomarker; and
(e) administering an anti-breast cancer therapy to the selected subject, wherein the anti-breast cancer therapy is a chemotherapy, a radiation therapy, a hormonal therapy, a targeted therapy, an immunotherapy, or a surgical therapy.