Patent ID: 11866409
Assignee: CARMEL-HAIFA UNIVERSITY ECONOMIC CORPORATION LTD.
Field: Pharmaceuticals (Chemistry)
Classification: CPC C  A | IPC A  C

Claim 0:
1. A method for inducing differentiation and/or apoptosis in a cell, wherein said method comprises the step of contacting said cell with an effective amount of at least one ARTS mimetic compound, any combination thereof any vehicle, matrix, nano- or micro-particle, or any composition comprising said at least one ARTS mimetic compound, wherein said ARTS mimetic compound having the general formula (I) or a pharmaceutically acceptable salt or hydrate thereof or any stereoisomer or salt thereof:, wherein:
R1 is independently selected from H, C1-C3 alkyl;
R2 is independently selected from —C(═O)—X—R3, —S(═O)—X—R3′; 
X is a heteroatom independently selected from O;
R3 and R3′, independently of each other may be selected independently from H, C1-C3 alkyl;
R5 is -L1-R7-L2-R8;
L1 and L2, independently of each other, are selected independently from —(CH2)n; —NH—C(═O)—(CH2)n—, —C(═O)—NH—(CH2)n—; —S—S—(CH2)n—; —O—(CH2)n—; —NH—(CH2)n—; C(═O)—(CH2)n—; —S—(CH2)n—; —NH—S(═O)n—(CH2)n—;
n is independently 1 to 3;
R7 is a carbocyclic ring or a heterocyclic ring;
R8 is a mono cyclic ring system having 5 to 12, optionally substituted with at least one of OH, CF3, halogen, —COOH, —NH2, CN, C1-C3alkyl; and
R6 is independently selected from H, halogen, CN, NO2, C1-C3 alkoxy, straight or branched C1-C3 alkyl.