Patent ID: 11911999
Assignee: WASHINGTON UNIVERSITY
Field: Measurement (Instruments)
Classification: CPC B  G  C | IPC B

Claim 10:
11. A method for enhancing a fluorescent signal of a fluorescent species, the method comprising:
placing a plasmonic patch in proximity to the fluorescent species,
exciting the fluorescent species using electromagnetic radiation of a predetermined wavelength thereby generating an enhanced fluorescent signal, and
detecting said enhanced fluorescent signal;
wherein the plasmonic patch comprises:
a flexible substrate comprising a first material,
a plasmonic nanostructure, and
a spacer comprising a second material;
wherein the plasmonic nanostructure is disposed on a first surface of the flexible substrate,
the spacer is disposed on the first surface of the flexible substrate and covers the plasmonic nanostructure;
the fluorescent species has an excitation wavelength (λex) and an emission wavelength (λem),
the plasmonic nanostructure has a localized surface plasmon resonance (LSPR) wavelength (λLSPR),
a difference between the LSPR wavelength and the excitation wavelength is |Δλ|; and
a density of the nanostructures on the flexible substrate is from 1/μm2 to 200/μm2.