Patent ID: 11872316
Assignee: DSM IP ASSETS B.V.
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  B | IPC A

Claim 0:
1. A particulate delivery system comprising coated particles adapted to deliver at least one nutraceutical to large intestines of a patient, wherein each of the coated particles consists of:
(a) 10-85 wt. %, based on total weight of the delivery system, of a particulate solid core consisting of butyric acid and/or salts thereof as a nutraceutical,
(b) 1-20 wt. %, based on total weight of the delivery system, of an inner coating having a substantially uniform thickness of 5 μm to 20 μm which covers the solid core, wherein the inner coating comprises at least one fermentable crosslinked biopolymer, and
(c) 1-30 wt. %, based on total weight of the delivery system, of an outer coating having a substantially uniform thickness of 10 μm to 30 μm which covers the inner coating, wherein the outer coating is formed of a material resistant to stomach and small intestine conditions to thereby allow release of the at least one nutraceutical in the large intestines of the patient.