Patent ID: 11878173
Assignee: DUKE UNIVERSITY
Field: Medical technology (Instruments)
Classification: CPC A | IPC A

Claim 13:
14. A method of treating Parkinson's disease in a human being comprising:
applying a non-regular pattern of electrical stimulation having a frequency range between 100 Hz and 200 Hz to a human being via an implanted lead in the human being's thalamus, subthalamus, or globus pallidus, wherein the non-regular pattern of stimulation comprises differing inter-pulse intervals between the pulses;
modeling oscillatory or synchronous activity in the human being; and
generating a subsequent non-regular pattern of electrical stimulation based on the modeled activity and applying the subsequent non-regular pattern of electrical stimulation to the human being via the implanted lead, wherein the subsequent non-regular pattern of electrical stimulation comprises a plurality of pulses having non-regular, non-random, differing inter-pulse intervals between the pulses and wherein the subsequent non-regular pattern of electrical stimulation is different from the non-regular pattern of electrical stimulation.