Patent ID: 11926841
Assignee: nan
Field: Biotechnology (Chemistry)
Classification: CPC C | IPC C

Claim 0:
1. A circular nucleic acid comprising in 5′ to 3′ direction
(i) at least one adeno-associated virus (AAV) inverted terminal repeat (ITR) sequence;
(ii) at least one AAV promoter which is capable of being activated by at least one helper polypeptide or helper polynucleotide originating or derived from a virus selected from Adenoviridae and Herpesviridae;
(iii) at least one AAV rep gene coding sequence under the control of said promoter of (ii);
(iv) an AAV promoter which is capable of being activated by said at least one helper polypeptide or helper polynucleotide originating from a virus selected from Adenoviridae and Herpesviridae;
(v) a transgenic coding sequence under the control of said promoter of (iv); and
(vi) an adeno-associated virus (AAV) inverted terminal repeat (ITR) sequence;
wherein said circular nucleic acid does not comprise an AAV cap gene.