Patent ID: 11925662
Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Field: Pharmaceuticals (Chemistry)
Classification: CPC A  C | IPC A  C

Claim 0:
1. A method of inhibiting tumor growth in a human subject, the method comprising:
(a) administering to the subject an effective amount of an anti-tumor antibody or an antigen-binding fragment thereof; and
(b) administering to the subject an effective amount of a human hybrid neutrophil, wherein the hybrid neutrophil co-expresses the canonical neutrophil associated molecules arginase-1(Arg1), myeloperoxidase (MPO), CD66b, and CD15, and the antigen presenting cell (APC) associated molecules CD14, HLA-DR, CD32, CD64, and CD89, thereby inhibiting tumor growth in the subject.