Patent ID: 11932868
Assignee: GREINER BIO-ONE NORTH AMERICA, INC.
Field: Biotechnology (Chemistry)
Classification: CPC C  B | IPC B  C

Claim 0:
1. A magnetic culture plate for three-dimensional (3D) cell culturing, comprising:
a) a standard ANSI-SLAS microtiter plate comprising a plurality of wells in an array and having a length of 127.76 mm ±0.5 mm and a width of 85.48 mm ±0.5 mm,
b) a cap comprising a magnetic holder and an intervening cover, wherein said cap is sized to fit over and cover said standard ANSI-SLAS microtiter plate, said cap having a lip around a circumference thereof and a plurality of magnets in an array, each magnet affixed to a depression in said magnetic holder, such that adjacent magnets are oriented in opposite polarity, wherein each magnet of the plurality of magnets protrudes inside a corresponding well of said intervening cover, said intervening cover being arranged between the magnets and the standard ANSI-SLAS microtiter plate and having a number of wells corresponding to a number of magnets of the plurality of magnets, said wells of the intervening cover configured to receive the magnets and to protrude inside the wells of the standard ANSI-SLAS microtiter plate when said cap is fitted in place over said standard ANSI-SLAS microtiter plate, such that each well of the standard ANSI-SLAS microtiter plate has a single magnet protruding inside said well of the standard ANSI-SLAS microtiter plate when said cap is fitted in place over said standard ANSI-SLAS microtiter plate, wherein the magnets do not touch a culture media inside said well, and wherein the cap holds the magnets at a fixed distance of 0.2 to 10 mm from said culture media inside said well of the standard ANSI-SLAS microtiter plate.