Patent ID: 11926809
Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL
Field: Measurement (Instruments)
Classification: CPC C  G  H | IPC C  G  H

Claim 14:
15. A system comprising:
a camera that produces an image of a semen sample;
a processor; and
a non-transitory computer readable medium storing instructions executable by the processor to provide an image processor that locates individual sperm within a representation of the image generated via an image processing technique in which a cross-correlation between a template representing at least a portion of a sperm and each of a plurality of locations on the image is computed and locations having a cross-correlation output above a threshold value are selected and generating a plurality of tiles from the image according to the locations of the individual sperm, a convolutional neural network that evaluates a subset of the plurality of image tiles and assigns each of the image tiles to one of a plurality of output classes, including a normal class and at least two abnormal classes, representing the morphology of sperm within the image tile, and a sample evaluator that records the one of the plurality of output classes assigned to each of the subset of the plurality of image tiles and assigns a metric representing the overall morphological quality of the semen sample from the recorded output classes for the plurality of image tiles as a linear combination of respective numbers of the plurality of individual sperm classified into each of the plurality of output classes.