"In the following example that you provided : What is the context of the word 'truncated ' ? The way I read it - it is talking about a truncated string of code or something . What was truncated ?"
"The gene and therefore the enzyme it produces . LPL is the designation for a gene that encodes Lipoprotein Lipase , an enzyme that hydrolyzes lipids in lipoproteins . The actual gene encodes a protein of 475 amino acids that becomes a mature protein of 448 amino acids after cleavage of a signal peptide . One study was able to identify 3 common SNPs ( Single Nucleotide Polymorphism ) in the coding region of the gene , 2 of which result in small changes in enzyme function in European populations . The third SNP converts that locus to a stop codon and results in an enzyme that is 447 amino acids long . Thus , the enzyme has been truncated . The resulting enzyme , LPL S447X , is functional . In fact , it results in lower incidence of vascular disease and lower blood pressure . Other truncations result in non-functional enzymes ."
"What was truncated ?"
"The gene and therefore the enzyme it produces ."