The resort is about 40 minutes from downtown Raleigh but was only about 20 minutes to our daughter and son-in-law's home. We looked at some other parks as we drove around the area and decided we made the right choice of where to stay especially to be close to family. When back in the area in the future we will probably stay here again. We had great Verizon and AT&T signals, the wifi was slow most of the time and we used our hotspot most of the time.


While in Raleigh, we not only got to spend a lot of time with Ally and Justin (daughter and son-in-law) and have Christmas with them, we also got to visit with Alan's nephew and wife. They had moved to the Raleigh area about a year ago so it was great to get so see them several times while in the area. We learned they are craft beer connoisseurs and went to a couple of fun breweries with them, our favorite being Deep River Brewing Company.


Raleigh is definitely a growing area and traffic is an issue depending on which way you are going at certain times of the day but got it figured out and other than trying to go to a mall right after Christmas managed to avoid most of the traffic.


The babies got to visit with their weenie cousin Copper while there. Copper grew up with our babies so they are all great friends and always remember each other every-time they see each other.


We spent Christmas eve and day at Ally and Justin's house with Kim & Ally having fun baking and such. Ally had just come back from basic training so was ready for real food and sleep! Christmas was a nice time with way too much food and presents for all.


The week after Christmas we took one day to drive to Wilmington and visit the beach. It was a gorgeous day, nice warm and sunny. We got in a good beach walk and Vinnie got to ride around the beach.Vinnie is starting to be able to support a little bit of his weight with his back legs but can't stand up by himself or walk without having a sling to support him. We knew this would be a long process but seeing that he is still happy and not in pain, we are glad that we didn't put him through surgery again.


The rest of the day in Wilmington we looked through some shops and had a nice lunch before heading back.


The rest of the time in Raleigh was visiting with both Ally & Justin and Chris & Jessica (Alan's nephew and his wife). We had a New Year's eve dinner at a Brazilian steakhouse and then went to spend midnight with the babies while the youngsters went out for midnight. Kim got to spend more time with Ally before Ally had to head back to Oklahoma to finish her basic training.


We got Vinnie in for the last of his laser treatments right before leaving and also for a follow up visit with the vet. She was happy with his progress but we know it will be a slow course for him and he may not get back to being able to get around on his own.


What does one need to get pre approved on a USDA Rural housing loan in Blounstown, FL? It's honestly still quite straightforward taking into consideration all the new changes which have … [Read more...] about USDA Mortgage in Blounstown, FL


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Filed Under: Location Tagged With: Altha Florida USDA Mortgage loan, Altha USDA Mortgage loan, Calhoun county USDA Mortgage<|endoftext|>Hipot Test Wiring Diagram have some pictures that related each other. Find out the newest pictures of Hipot Test Wiring Diagram here, so you can have the picture here simply. Hipot Test Wiring Diagram picture uploaded and submitted by Www.rangkaianelektronika.co that preserved inside our collection.


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1256165  a single-bitcoin trade Restrict for all Bisq users. This limit may be relaxed Later on.<|endoftext|>(a) Eligibility. (1) Every alien in the United States who is classified as a refugee under part 207 of this chapter, whose status has not been terminated, is required to apply to the Service 1 year after entry in order for the Service to determine his or her admissibility under section 212 of the Act.


(b) Application. Upon admission to the United States, every refugee entrant shall be notified of the requirement to submit an application for permanent residence 1 year after entry. An application for the benefits of section 209(a) of the Act shall be filed on Form I-485, without fee, with the director of the appropriate Service office identified in the instructions which accompany the Form I-485. A separate application must be filed by each alien. Every applicant who is 14 years of age or older must submit a completed Form G-325A (Biographical Information) with the Form I-485 application. Following submission of the Form I-485 application, a refugee entrant who is 14 years of age or older will be required to execute a Form FD-258 (Applicant Fingerprint Card) at such time and place as the Service will designate.


(c) Medical examination. A refugee seeking adjustment of status under section 209(a) of the Act is not required to repeat the medical examination performed under §207.2(c) of chapter I, unless there were medical grounds of inadmissibility applicable at the time of admission. The refugee is, however, required to establish compliance with the vaccination requirements described under section 212(a)(1)(A)(ii) of the Act, by submitting with the adjustment of status application a vaccination supplement, completed by a designated civil surgeon in the United States.


(d) Interview. The Service director having jurisdiction over the application will determine, on a case-by-case basis, whether an interview by an immigration officer is necessary to determine the applicant's admissibility for permanent resident status under this part.


(e) Decision. The director will notify the applicant in writing of the decision of his or her application for admission to permanent residence. If the applicant is determined to be inadmissible or no longer a refugee, the director will deny the application and notify the applicant of the reasons for the denial. The director will, in the same denial notice, inform the applicant of his or her right to renew the request for permanent residence in removal proceedings under section 240 of the Act. There is no appeal of the denial of an application by the director, but such denial will be without prejudice to the alien's right to renew the application in removal proceedings under part 240 of this chapter. If the applicant is found to be admissible for permanent residence under section 209(a) of the Act, the director will approve the application and admit the applicant for lawful permanent residence as of the date of the alien's arrival in the United States. An alien admitted for lawful permanent residence will be issued Form I-551, Alien Registration Receipt Card.


(a) Eligibility. (1) Except as provided in paragraph (a)(2) or (a)(3) of this section, the status of any alien who has been granted asylum in the United States may be adjusted to that of an alien lawfully admitted for permanent residence, provided the alien:


If the application for adjustment filed under this part exceeds the refugee numbers available under section 207(a) of the Act for the fiscal year, a waiting list will be established on a priority basis by the date the application was properly filed.


(2) An alien, who was granted asylum in the United States prior to November 29, 1990 (regardless of whether or not such asylum has been terminated under section 208(b) of the Act), and is no longer a refugee due to a change in circumstances in the foreign state where he or she feared persecution, may also have his or her status adjusted by the director to that of an alien lawfully admitted for permanent residence even if he or she is no longer able to demonstrate that he or she continues to be a refugee within the meaning of section 10l(a)(42) of the Act, or to be a spouse or child of such a refugee or to have been physically present in the United States for at least one year after being granted asylum, so long as he or she is able to meet the requirements noted in paragraphs (a)(1)(i), (iv), and (v) of this section. Such persons are exempt from the numerical limitations of section 209(b) of the Act. However, the number of aliens who are natives of any foreign state who may adjust status pursuant to this paragraph in any fiscal year shall not exceed the difference between the per country limitation established under section 202(a) of the Act and the number of aliens who are chargeable to that foreign state in the fiscal year under section 202 of the Act. Aliens who applied for adjustment of status under section 209(b) of the Act before June 1, 1990, are also exempt from its numerical limitation without any restrictions.


(b) Inadmissible Alien. An applicant who is inadmissible to the United States under section 212(a) of the Act, may, under section 209(c) of the Act, have the grounds of inadmissibility waived by the director (except for those grounds under paragraphs (27), (29), (33), and so much of (23) as relates to trafficking in narcotics) for humanitarian purposes, to assure family unity, or when it is otherwise in the public interest. An application for the waiver may be filed on Form I-602 (Application by Refugee for Waiver of Grounds of Excludability) with the application for adjustment. An applicant for adjustment who has had the status of an exchange alien nonimmigrant under section 101(a)(15)(J) of the Act, and who is subject to the foreign resident requirement of section 212(e) of the Act, shall be eligible for adjustment without regard to the foreign residence requirement.


(c) Application. An application for the benefits of section 209(b) of the Act may be filed on Form I-485, with the correct fee, with the director of the appropriate Service office identified in the instructions to the Form I-485. A separate application must be filed by each alien. Every applicant who is 14 years of age or older must submit a completed Form G-325A (Biographic Information) with the Form I-485 application. Following submission of the Form I-485 application, every applicant who is 14 years of age or older will be required to execute a Form FD-258 (Applicant Fingerprint Card) at such time and place as the Service will designate. Except as provided in paragraph (a)(2) of this section, the application must also be supported by evidence that the applicant has been physically present in the United States for at least 1 year. If an alien has been placed in deportation or exclusion proceedings, the application can be filed and considered only in proceedings under section 240 of the Act.


(d) Medical examination. An alien seeking adjustment of status under section 209(b) of the Act 1 year following the grant of asylum under section 208 of the Act shall submit the results of a medical examination to determine whether any grounds of inadmissibility described under section 212(a)(1)(A) of the Act apply. Form I-693, Medical Examination of Aliens Seeking Adjustment of Status, and a vaccination supplement to determine compliance with the vaccination requirements described under section 212(a)(1)(A)(ii) of the Act must be completed by a designed civil surgeon in the United States and submitted at the time of application for adjustment of status.


(e) Interview. Each applicant for adjustment of status under this part shall be interviewed by an immigration officer. The interview may be waived for a child under 14 years of age. The Service director having jurisdiction over the application will determine, on a case-by-case basis, whether an interview by an immigration officer is necessary to determine the applicant's admissibility for permanent resident status under this part.


(f) Decision. The applicant shall be notified of the decision, and if the application is denied, of the reasons for denial. No appeal shall lie from the denial of an application by the director but such denial will be without prejudice to the alien's right to renew the application in proceedings under part 240 of this chapter. If the application is approved, the director shall record the alien's admission for lawful permanent residence as of the date one year before the date of the approval of the application, but not earlier than the date of the approval for asylum in the case of an applicant approved under paragraph (a)(2) of this section.


[46 FR 45119, Sept. 10, 1981, as amended at 56 FR 26898, June 12, 1991; 57 FR 42883, Sept. 17, 1992; 63 FR 30109, June 3, 1998; 74 FR 55742, Oct. 28, 2009]<|endoftext|>The VIE HR Project Management Specialist is in charge of coordinating, adapting and implementing the HR corporate Digital strategy to our region's needs and level of maturity while ensuring it is perfectly in line with central guidelines. The HR VIE will also provide full support to the Head of HR Development on key HR development projects in the Region. Coordination and support to internal stakeholders is key.


In coordination with the Central HR team in Paris, provide support for the implementation/coordination of the induction plan for all new hires in the region (Dior Online induction, on boarding welcome box)<|endoftext|>Grabemployment July 12, 2018 July 12, 2018 No Comments on DENA BANK Recruitment for FINANCIAL LITERACY COUNSELLOR<|endoftext|>Great pair of tits Emzy, love your ass on the other site too! One sexy lady with a great body! Please keep posting as I really need to keep viewing


1256166  say “I don’t know how to sabotage a car” but then realised I’d get *loads* of practice if I wanted it, so maybe things like that and anonymous 911 calls would do it…


I suppose one thing I could do (if I hadn’t seen X Men) would be to let the secret service be aware of what I can do and then they can use their clout to save people/inform the police etc. Of course, I definitely wouldn’t do this because I have seen X Men.


Easiest option (doesn’t require the car keys or any tools other than a matchstick, does no lasting damage, will work on most cars) is to let down some or all of the tyres.


Of course, this won’t delay the driver by very long, but I imagine it would be long enough that they avoid the accident. Also, it stops the car from moving *at all*, whereas something like putting sugar in the fuel tank (as used by WW2 Resistance saboteurs), as well as doing permanent expensive-to-fix damage, will allow the car to move initially- possibly enough to get into the accident, if it doesn’t cause an accident by killing the engine in high-speed traffic.


Most car accidents involve complex patterns of traffic. If Joe gets into his car at 8:30 and drives to work, at 8:50 gets stuck behind Larry who is aggravating because he’s soooo slooooowww, and tries to pass and crashes at 8:50 into Brenda, who wasn’t driving defensively enough. It is probably sufficient to just delay Joe by 1 minute. Or Brenda. Or Larry.


If you were to replay the day over and over, you would find that there are all sorts of things you can do everywhere that increase or decrease total traffic deaths that day in that city. Since the baseline is 100 deaths per day across the US, most cities will have zero on most days, so simply “re-rolling” by messing with any participants is usually enough to get the death rate to zero.


I’d love to see confused pundits discussing the fact that one city’s road traffic accidents have gone down to zero ever since such-and-such a date, politicians claiming credit, the city getting a reputation for being careful and respectful…


Also keep in mind that you could easily target the “low-hanging fruit.” Complex accidents may be hard to fully solve or prevent, or you might just change who dies and who doesn’t.


But things like “a drunken trucker killed a family of 3 by running a red light on a remote rural road at midnight” are probably preventable.


Or accidents in general. Small children drowning in pools? Call the parents beforehand! They don’t believe you? Defecate in their pool!


Eliza Dushku didn’t have too much trouble with it, and left an entertaining series of instructional videos. Well, OK, it started getting troublesome when that guy from Beverly Hills showed up with his own time machine, but we never did learn his agenda.


Having never seen it, is that show any good? I’ve never been much impressed with Dushku in e.g. Dollhouse (Buffy she was OK–one note, but a good note) but I certainly want it to be good.


You can give people advance warning of Very Bad Things about to happen, and eventually establish a reputation as a reliable prophet “short-term superforecaster”. Probably best to do this anonymously. Whether you eventually want to trade on that reputation by making a few carefully chosen false prophecies forecasts is an interesting question.


From the pure money-making perspective, the stock market isn’t the way to go – your activities are visible and if your returns are suspiciously good the government will want to have a word with you. Stocks might be ok for making your first few millions, but in the long run you’d want to get into something like currency markets – they have the capacity to absorb extremely large bets and no one suspects insider trading there.


Done well, you look like a secretive hedge fund with real ‘alpha’. Billions or tens of billions over a (say) ten-year horizon could be easily made acceptable, but


(e.g. well out-of-the-money derivatives) whose success depend on natural disasters would invite scrutiny, but you’d probably be able to survive the governmental kind because how can you be an insider? (There are other risks though.)


I still think an effective way is to prove/sell yourself as a reliable predictor of natural disasters (and only them) and though that might be good enough in itself, if you want more cash just charge a huge fee for your services (even contingent: buy my services, and if I predict disaster level X for your country, you pay me $Y(X) if I’m right, but get paid $Z(X) if I’m wrong; once I have a good track record, no-one will not be rationally willing to enter some such deal [and so in equlibrium I do all the good I would do even fully altruistically, but get paid as well])


You could probably wrangle a large retainer to, under no circumstances, provide military advice to any country. Then give that retainer to charity.


Or, you could go on a world conquest spree. In any other period but ours I’d say a 24 hour rewind would guarantee you winning any war you happened to lead. These days one day battles are less important but a complete strategic immunity to surprise attacks is one hell of an advantage. Not sure you can do much good with that ability, but if you fancy that you’d make a better despotic ruler than the alternative…


Didn’t the Other Scott or someone prove that you can use this to solve PSPACE problems in polynomial time?


You could solve any brute-forceable algorithm. As long as you can order the inputs, you can tell the computer at the start of the day “this is day N, go.”


This brings up another way to make money: crypto currencies. It’s been a while since I wrote any software here, but last I did, mining a block depends on solving a Very Hard Problem By Bruteforce, but that problem is well-defined by the answer to the previous block. So you could check that the problem was at the start of your time-travelling day, precalculate the next N blocks, and then go.


It won’t work to reuse someone else’s calculations for Bitcoin block hashes, because I’m pretty sure the block hash includes the Bitcoin address to which the mining rewards will go. Changing that to your address means the block hash isn’t good anymore.


OTOH, if you have mining hardware, you can spend 24 hours trying to compute the next block hash, then send that information back in time to yourself. Assuming your process for finding the next block hash is deterministic, this won’t mess up your calculation. You can also use the chaining trick, above, to get as big a multiplier as you need to get that block reward.


Yes, this (that a BTC solution claim includes the claimant’s address, keeping you from presenting someone else’s solution as your own) is essentially true. The iterative approach is technically possible, but impractical – back of the envelope, a million bucks worth of ASIC miners would get you about 1/4000th of the BTC hashrate, meaning that you’d have to re-live nearly a subjective month to win a 10-minute $10,000 block. That’s a looooot of time to think up ways to persuade the SEC you’re just really good at picking penny stocks.


Hmm, what happens if there’s an address collision, two people claiming the same address at very close to the same time? If Alice is observed to use an address to receive but not spend BTC on The Day, can Bob copy their work at the end of the day, go back to the start, have spurious BTC sent to Bob@alicesaddress, and then spend them for something suitably untraceable before Alice notices?


A quick google suggests that while addresses aren’t supposed to be reused, there are some careless Alices out there who do it anyway, and may present an additional attack surface for this.


Bitcoin addresses are 160-bit cryptographic hashes of a public key. To claim the rewards, you need the associated private key. Without a fundamental break in elliptic-curve cryptography, you can’t steal somebody else’s address, and without a truly phenomenal amount of work (much larger than just mining a block) you can’t find a hash collision that lets you use a different keypair for the same address.


Address reuse has serious failure modes, but I don’t think any of those failure modes become extra-vulnerable to people travelling back in time.


I feel like there is some analog of the Nyquist limit at play. You can only detect signals that arise within 24 hours. Your error-detection is “bandlimited.” Moreover, unless you are willing to find and integrate an enormous amount of information, your SNR is probably not going to be very good. All this despite being able to exert very powerful control over your sphere of influence, and being able to expand that sphere of influence through riskless gambling. So I worry that you could unknowingly work your way into an inescapable and broadly-reaching consequence, with no way


1256167  came equipped with extras like four wheel steering. The Series l cars were available between (1989-1991), they came packing a turbo 4-cylinder 1.8lt CA18DET engine under its long sloping bonnet. This unit pushed out 175hp and was good to get the 180 SX from 0-60mph in around 6.9sec and top speed around 146mph. The 180SX name remained unchanged on the series ll cars (1991-1995) even though Nissan had stuck the more powerful 2.0lt engine option into it. They now had 202hp from the bigger 2.0lt SR20 Det turbocharged engine. It came with double overhead camshafts and 4 valves per cylinder. The Series ll cars was now good for the 0-60mph in around 6.4sec and top speed around 146mph. The Series lll cars (1996-1998) kept the same 202hp powerplant but it got revised tail lights and front bumper. Three different trim levels were offered, Type X, Type R and they only non-turbo model, the Type S. It had to make do with only 138hp from it's 2.0lt and it could only do the 0-60mph in 7.7sec. .. 📷 @paulharoldd . #rps13 #180sx #nissan #240sx #schassis #sr20det #kouki #sr20 #typex #drifting #180sxgram #180sxtypex #180sxnation #te37 #volkracing #jdm #rayswheels #volk #te37sl #stancenation


Not every day you come across an S14 drag car. Spotted it earlier this year at TX2K while the owner was getting the car dialed in for a pass.<|endoftext|>The scattering of electromagnetic radiation through nonspherical debris has turn into an more and more very important examine subject over the last twenty years. rather than dealing with anisotropic debris of arbitrary form, the authors give some thought to the extra amenable challenge of aggregates of round debris. this can be a truly passable procedure because the optical reaction of nonspherical debris relies extra on their normal symmetry and the volume of refractive fabric than at the exact info in their form.


Those pages current a set of contemporary papers basically documenting the nascent technological know-how of neutrino geophysics. many of the papers from talks given at Neutrino Sciences 2005: Neutrino Geophysics held on the college of Hawaii in December 2005. numerous papers have been solicited later so as to make the gathering as accomplished as attainable.


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At a radial distance of around 1016:6 cm, large molecules grow in a relatively dense, n(H2 ) $ 105 cmÀ3 , low UV environment. Beyond 1017 cm, the external UV Weld is large enough to destroy complex molecules unless the chemistry is able to produce photoresistant molecules. Fig. 2 shows also that the abundance of large molecules produced in the outer envelope decreases with increasing size, a reXection of the ineYciencies of the chemical synthesis in a Xow expanding into a region of increasing UV Xux.


The observation of molecules in disks is at the forefront of current receiver technology, and while new facilities like the Submillimetre Array (SMA) or the Atacama Large Millimetre Array (ALMA) will greatly increase our knowledge of these objects, many simple organic molecules, also found in the interstellar medium and in comets, have already been detected in such disks. Dutrey et al. (1997) reported the molecular content of the disks around the T Tauri stars DM Tau and GG Tau. They detected transitions in CO, HCN, CN, CS, H2 CO and HCOþ in both disks.<|endoftext|>Clarity, excitement, precision – but you already know that from our sports cars. With a love of detail, we have created individual accessories for creative drivers who wish to shape their own environment. Ordering items online from the Porsche Driver's Selection is a quick and easy process.<|endoftext|>When I stop to reflect on what is BEST practice for my elementary ELLs in reading, writing, listening, and speaking, the answer comes to me quite clearly…the workshop model. Why? What I know about the needs of my ELLs is that they require explicit instruction, modeling, guidance, routine, and practice. Here’s how the reading and writing workshop models promote progress for ELLs in listening, speaking, reading and writing.


The reading and writing workshops follow a specific daily routine. There is a structure to the workshop that is followed in order for each component to happen daily. The routine helps all students know what to expect. This is especially great for ELLs since they are (possibly) navigating a new language, school system, and culture.


One of the components of both the reading and writing workshop is the mini-lesson. During the mini-lesson, the teacher gives direct instruction and explicitly shares with students what will be expected of them as readers and/or writers. ELLs need to know exactly what is expected of them as readers, writers and speakers. Since the mini-lesson is short, there is not a lot of teacher talk. One way to make the mini-lesson even more ELL friendly is to slow down speech and stop for a structured turn and talk. During this portion of workshop, ELLs are practicing listening and some speaking as well.


Anchor charts are a key piece of the mini-lesson. This is how the teacher leaves a fingerprint of the teaching. The anchor chart should be able to support students as they go into independent work. It allows the teacher to work with small groups or confer one-on-one with students without being constantly interrupted by students who need re-teaching. For this reason, the anchor chart should be comprehensible for students. Limit the text and support the text with visuals and graphics. The anchor chart should give students clear, step-by-step guidance for their work.


The biggest piece of the reading and writing workshops is independent reading/writing time. During this block of time, students work on their own reading and/or writing.


During reading workshop students are reading self-selected books at their reading level. Selecting books can be tricky. I don’t want my ELLs to feel bad if their reading level is way below their grade level in English. It can be hard to find texts that they can read but are still relevant and interesting to them. Adapted texts and nonfiction texts are great here. I also encourage my ELLs to continue reading in their native language. The bridge between L1 (first language) and L2 (second language) can be strong if we continue to nurture it.


During writing workshop students are writing their own pieces of work. Providing students with touchstone texts, exemplars, or target texts is key here. All students need to see what their goal is in writing so they can aim to achieve it. And not everyone’s goal will be the same. It certainly won’t be to write like an adult author. Though I love using mentor text written by great adult authors, when it’s time for students to do their own writing, I give them examples they can achieve (in their ZPD). The best examples are student written so start saving some student examples to use year after year!


Whether we are in reading or writing workshop, students are practicing what the teacher has taught during minilessons. Within independent reading and writing block the teacher is able to work with students in smaller settings to meet their specific needs. The teacher can pull a guided group, a strategy group, or work with students one-on-one. No matter which of these methods is selected daily, students’ needs lead the decision. ELLs benefit from these smaller settings where the teacher/student ratio is lowered. These smaller settings also help to lower the affective filter for ELLs. When ELLs need time to process their thinking, possibly translate language, and build courage to answer, a smaller setting provides comfort. The anxiety level is lowered and students feel safe to respond and collaborate. In addition, the smaller setting allows for more interaction helping our students to have extra opportunities to practice the new skills they have been taught and the new language. During independent time, ELLs are practicing reading and/or writing, listening, and speaking.


The final piece of reading and writing workshop is share time. For some ELLs, sharing in whole group can be intimidating. One strategy that has been found to alleviate stress for ELLs before they share with whole group is to allow them rehearsal time. Giving ELLs time to practice what they will share builds their confidence before they share with the class. Some ELLs will need sentence stems or starters to help them produce sentences that are grammatically correct while others will not need this type of scaffold. During this portion of the workshop, ELLs are practicing listening and speaking (if they are sharing).


I


1256168  of 55 ± 0.1°C. Paw withdrawal thresholds were determined in the hind paws of ipsilateral hind limb. Animals were kept on the plate until the first sign of ipsilateral paw lift or lick was recorded as basal withdrawal latency (pre-drug latency). A maximum cut-off paw withdrawal latency of 20 seconds was chosen to prevent tissue damage (cut-off time). Post-dose thresholds were taken at 5, 15, 30, and 60 minutes after drug administration (post-drug latency). For each animal, results were expressed as the percentage maximum possible effect (%MPE) calculated using the following formula: [(post-drug latency - pre-drug latency)/(cut-off time - pre-drug latency)] × 100.


Inflammatory pain was assessed using the formalin test. Ten μl of a 5% formalin solution was injected subcutaneously into the plantar surface of the right hind paw of CD1 mice. After the injection, mice were immediately placed in a plexiglas box (20 × 15 × 15 cm) surrounded by mirrors to allow the observation of nociceptive responses that include licking, lifting and shaking of the injected paw. Tests were performed between 08:00 h and 12:00 h to minimize variability. Mice were observed for 1 hour. Formalin scores were separated into two phases, phase I (0-10 min) and phase II (15-45 min). The mean behavioural score was calculated in blocks of 5 min for each of the two phases. A mean response was then calculated for each phase.


CD1 mice that received intraplantar injection of kisspeptin or vehicle were placed in a cage immediately after the injection, and the duration of hind paw lifting and licking during the first 5 minutes were measured.


Animals were euthanized with chloral hydrate (320 mg/kg i.p.). 2.5-mm punch skin biopsies from the plantar surface of the hind paws were performed and fixed in Zamboni fixative (2% paraformaldehide, 15% picric acid saturated aqueous solution, 0.1 M phosphate buffer pH 7.4) for 24 hours. Biopsies were cryoprotected with 20% sucrose in PBS overnight at 4°C. Sections of 10 μm were cut at the cryostat and mounted on glass slides for immunohistochemical analysis.


Immunohistochemistry procedures were performed as previously described [14]. Double immunofluorescence was performed in skin biopsies from CD1 male mice incubating sections overnight with polyclonal rabbit anti-human PGP 9.5 (1:1000; AbD Serotec, Kidlington, UK) and goat polyclonal anti-GPR54 (1:20; Santa Cruz Biotechnology, Santa Cruz, CA) and then for 1 h with secondary fluorescein anti-rabbit (1:100; Vector Laboratories, Burlingame, CA) and Cy3 anti-goat (1:400; Chemicon, Billerica, MA) antibodies. Control staining was performed without the primary antibodies.


Immunostaining was performed in skin biopsies from male 129S6/Sv/Ev wild-type and 129S6/Sv/Ev Gpr54- knock-out mice [13] to test the specificity of the anti-GPR54 antibody. Tissue sections were incubated overnight with goat polyclonal anti-GPR54 (1:20; Santa Cruz Biotechnology, Santa Cruz, CA) and then for 1 h with secondary biotin-coupled anti-goat (1:100; Vector Laboratories, Burlingame, CA). SG (SG substrate kit; Vector Laboratories, Burlingame, CA, USA) chromogen was used for detection.


CD1 mice (n = 5 per group) were used. 3 min after kisspeptin (3 nmol) or vehicle (DMSO) were co-injected with formalin in the right hind paw and lumbar spinal cords were removed and fixed in formalin (4%) overnight, transferred in 70% ethanol and included in paraffin. Ten serial sections were cut and used for immunohistochemical analysis. Deparaffinized sections were treated with 10 mmol/L citrate buffer, pH 6.0, and heated by microwave for 10 minutes for antigen unmasking. Sections were soaked in 3% hydrogen peroxide to block endogenous peroxidase activity. Tissue sections were incubated overnight with monoclonal rabbit antibody anti-phospho-p44/42 (Erk1/2) (Thr202/Tyr204) (D13.14.4E)XP™ (1:200; Cell Signaling Technology, Denver, MA, USA) and then for 1 h with secondary biotin-coupled anti-rabbit (1:200; Vector Laboratories). 3,3-Diaminobenzidine tetrachloride was used for detection. Control staining was performed without the primary antibodies.


Intensity of p-ERK immunoreactivity was quantified by measuring the optical densities of the outer laminae of the dorsal horn in the stained sections relative to the background (ventral horn). Images were acquired using a computer-based microdensitometer (NIH Image Software, Bethesda, MD, USA). Values were the mean of measurements made on ten sections (10 μm) sampled 1 into a 3 series spanning the extent of the L4-L5 spinal cord.


CD1 Mice were sacrificed 3 min following treatment and skin lysates of all groups were processed in western blot. Skin homogenates were obtained as previously described [15]. Ten μg of total protein were separated by 10% SDS-polyacrylamide gel electrophoresis and electrophoretically transferred onto protein-sensitive nitrocellulose membranes (Criterion blotter; Bio-Rad Laboratories, Hercules, CA). The membranes were blocked in Odyssey blocker (LI-COR Biosciences, Lincoln, NE) for 1 h, and the following primary antibodies were used: anti-TRPV1 (phospho S800) polyclonal antibody (1:400, Abnova, Aachen, Germany); anti-actin monoclonal antibody (1:1000, Sigma). Secondary antibodies were: goat anti-rabbit (IRD800CW) and goat anti-mouse (Alexa 680, LI-COR, Bioscience) antibodies. Proteins were detected with the Odyssey Infrared Fluorescence Imaging System (LI-COR).


Knowing that the kisspeptin receptor, GPR54 (KISS1R), is present in DRG neurons [12], we performed immunofluorescent analysis to examine whether the receptor was also present in peripheral nociceptors. We focused on the peripheral role of kisspeptin in the modulation of acute and inflammatory pain. First we examined the specificity of the GPR54 antibody in skin biopsies from GPR54 KO mice. No immunostaining was seen in sensory nerve terminals of GPR54 KO mice (Figure 1). The nature of the nonspecific staining seen in the outer portion of the skin of GPR54 KO mice is unknown. In punch skin biopsies from the mouse hind paw, sensory fibers ascending vertically between the keratinocytes to reach the stratum corneum of the epidermis were identified by fluorescent immunostaining for the neuron-specific ubiquitin hydrolase, PGP9.5 [14] (Figure 2A). These fibers also expressed GPR54, as shown by double fluorescence immunostaining (Figure 2B, C). Behavioral experiments were performed after peripheral (intraplantar) and central (intrathecal) administration of kisspeptin at doses ranging from 0.1 to 3 nmol [16]. We first examined the effect of intraplantar injection of kisspeptin on nocifensive behavior in naïve mice. Nocifensive behavior consisting of licking, flinching and shaking of the injected paw was evaluated after a single injection of kisspeptin (3 nmol/5 μl) or vehicle into the plantar surface of the right hind paw. The time spent in nocifensive behavior was recorded for 5 min after the injection. Intraplantar injection of kisspeptin (3 nmol/5 μl) induced brief nocifensive behavior that lasted for about 5-15 seconds, whereas no signs of pain were seen in vehicle-injected mice (Figure 3A). We then assessed the effect of kisspeptin on acute thermal pain using the hot plate test. Intraplantar injection of kisspeptin (3 nmol/5 μl) significantly reduced paw withdrawal latency in response to heat as compared to intraplantar injection of vehicle (Figure 3B), whereas no differences were observed after p234 injection (0.1 nmol/5 μl) (Figure 3C).


Double immunofluorescent staining for the kisspeptin receptor, GPR54, and PGP9.5 in the mouse skin. Immunofluorescent staining of PGP9.5 and GPR54 is shown in (A) and (B), respectively. Co-immunolocalization is shown in (C) (see arrowheads). Scale bar 20 μm.


Intraplantar injection of kisspeptin lowers pain threshold in the hot plate. The nocifensive response to intraplantar injection of kisspeptin (3 nmol/5 μl) in naïve mice is shown in (A). Data are means ± S.E.M of 6 mice, and refer to the number of sec spent in licking behavior in the first 5 min following injection. *p < 0.05 (Student's t test


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Mateo Gonzales presses play and the track springs to life. The window on his laptop shows various layers of composition scrolling by. There’s a sample of Bobby Day’s “Rockin’ Robin.” The trilling whistle of the early rockabilly hit leaps from the small computer speakers, as do the more tinny rhythmic elements: the high…


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If you are a member of any of the following groups, contact us today to learn more about the program and to get a free quote.<|endoftext|>Title Handbook of Australian, New Zealand and Antarctic Birds, Volume 6: Pardalotes to Shrike-thrushes.<|endoftext|>Tuesday morning, my last full day in this little volcanic paradise where the sun always shines. The trouble with holidays is they’re always way too short, and cold, hard reality is always there at the end of them. For some reason I’ve woken every morning at around seven, later than I would at home but earlier than I normally would on holiday. Each morning I’ve crept out onto the balcony as quietly as I can and sat, listening to the pigeons cooing, the birds waking up and the sea crashing against the rocks below my window. Slowly the sky has turned from dark, inky blue to white clouds tinged with pink. It’s nice to have the time to sit and watch the dawn.


It feels like we’ve just scratched the surface of this wonderful little Island. There is so much we haven’t seen but, of course, this means we can return to see some more. Today is about taking the time to sit, with the warm sun playing on my skin, in a little garden where I can gaze at the scattered pink bracts fallen from the bougainvillea, drifting in the breeze across the courtyard. Taking a leisurely stroll along the beach with the sea lapping at my feet. Sipping a cup of wonderful coffee in the Nud d’Naplun with the breeze cooling us. Wandering along streets of shops filled with tacky souvenirs and almost buying things for their tacky, quirky awfulness.


We lingered over our coffee, gazing at the breathtaking view reflected in the window, then turning around to see it for real. No matter how much we dawdled, the coffee was gone all too soon and we went inside to say a final goodbye to the surfer dude. We may pop in tomorrow before we leave but then again we may not have time. On the way back a cat that looked suspiciously like fluffy crossed our path, surely not!


With one last look at the bikes for hire that we’d dodged every day and the pretty tables outside Nud d’Naplun we turned to make our way back. One last paddle in the warm sea. One last chill by the pool on our sun beds. Sand between my toes and sun on my skin. I will miss this. We joked about winning the lottery and island hopping for the rest of our days. If only…


While I was doing all this I felt a buzzing in my handbag. My phone was ringing. It was Jessica from the agency to tell me the cruise firm liked the sound of me and wanted to arrange an interview on Friday, just after I get home. Good news? Maybe. It is at least encouraging that someone is interested. Even so, the real world worries worming their way into my little slice of paradise unsettled me, brought the grey skies and cold rain crowding in along with the thought of a job to be found. In short, it reminded me of what I have to go back to all too soon.


A few days ago I promised I’d give you a little tour of the Gran Melia Salinas hotel so I guess, while I’m sitting here catching some rays, I will tell you all about it. Designed by the architect Fernando Higueras, with a great deal of assistance from none other than Cesar Manrique, the hotel won the prestigious Pritzker International Architecture Prize. Meliá Salinas is filled with art, paintings, sculptures and murals, many of which were designed by Manrique himself. The thing that makes it so very special though is the atrium, set out as three large round interconnected spaces, designed to mimic larva bubbles, and planted as lush gardens. There are more than three hundred plants, ponds, pools, waterfalls, little larva paths and bridges.


The largest of the three spaces, closest to the reception is open to the sky above, the other two have glass roofs. Walking on the meandering paths feels like walking through a rain forest, trees towering above. It’s easy to forget you are actually inside a hotel, until you catch the occasional glimpse of the hotel shops through the foliage. I could have spent hours just wandering and looking at the amazing plants and beautiful flowers, the fruit forming on the palms, the tinkling water features.


This wonderful garden won the Euroos Nistra, the Global Ecology and Tourism prize, the Golden Medal of Fine Arts, the Goslarer Monchenhaus Prize for Art and Environment and the Nederlans Laureat Van D’Aheod. It is kmown as Lanzarote’s botanical cathedral and I feel privileged to have called it my home, even if only for one week. Every morning, when I come out of my room and look down over the gardens I have to pinch myself to make sure I’m not dreaming, it is so very beautiful. Here plants that I have only ever thought of as delicate pot plants grow like huge shrubs. This is where I saw the monstera fruiting along with bird of paradise flowers, crotons acting as underplanting, like the garden of my dreams. Manrique wanted to create


1256170 �t deny the fact that some professionals prefer to work in this kind of way due to the fact that it brings greater personal satisfaction instead of working for someone. In freelancing you’re the one who holds your time but the drawback is that the money you earn is not stable unlike in a regular office work. So for those people who thinks about working, think about making connections first before engaging into freelancing. Working in an office environment is a great training ground for most people around the world.


It’s hard when you’re trying to land a freelance job for the first time. You checked for forums, websites, groups, watch tutorial videos, etc. You even ask yourself, “Is it going to be worthy?” “Will it work out for me?” “Should I go back to the corporate world?” I know you all have the same questions. Freelancing is never that easy. You need focus, perseverance and good attitude towards the job you’ve been wanting to land on. There will always be pros and cons with freelancing. The fact that you will not be commuting every day, you will not rush, you’ll be able to do some chores even while working and of course, more time with the family. Isn’t it that great? However, if you are just stagnant on your workstation without doing some exercise, well then it’s going to be a health risk. I’m not generalizing, but this happens a lot to us, freelancers. We skip meals, bath and other hygienic rituals we used to do. Even at home, we should maintain proper hygiene and cleanliness. Not because you’re just at the comfort of your home then you’ll not pay attention to yourself. That’s wrong. Again, it will still depend on us if we choose not to be hygienic.


Freelancing has played a big role to people. Freelancing helped a lot and still ramping. Yet, I am in awe if there’s really a big growth staying at home doing freelance. I have a lot of questions, too. I do freelancing, yes, because I’m a stay at home wife and mom. I’m grateful still with the freelance community for helping me out.


I see freelancing as the wave of the future, it sort of reminds me of ancient times, when bartering was used more often than exchanging currency. Thanks to the internet, marketing of one’s personal services has been much easier thereby allowing many talented individuals to offer their special brand of services to the masses. Freelancing also offers you the freedom of not being tied to a desk in the usual 9-5 scenario. I found from personal experience that freelancing has many rewards, but with their being so many competing for the same jobs, it is often difficult to create a steady stream of income, which is the reason I perform a combination of a part time job and a bit of freelancing. I highly recommend giving freelancing a try, but your success will depend on how well you market yourself and how much of a demand there is for your services.


I’d love to freelance, but from what I know it’s for jobs that can be taken from home and more IT-oriented tasks and not, say, salesman profession. What if I am not IT person? I’d love to find something like temporary substitute for people who fell ill, or otherwise undisposed and cannot perform their work, but cannot find sites for that kind of work. Maybe anyone knows them?


A lot of people, specially those who are seeking online jobs or those who want to make money online, thinks that jobs online like freelancing is easier than having a regular job like the ones they have (if they already do have one) but the truth is, it’s really the same. The time and the flexibility of the job may make a difference but the dedication and hard work that you put into work is all the same if you really want to pursue this career path. If you still wanna try to become a freelancer, you can try it out first but never ever quit your regular job just yet in case things doesn’t go your way at freelancing.


If you want to start being a freelancer, it’s a good idea to ask for help from those who have personal experience about the career path your trying to venture on. Their insights of what to expect about the ups and downs on being a freelancer will help you in dealing with situations that aren’t really going your way. Having a constant connections with them will also help you grow as a freelancer and may also result in a collaboration if your field is of the same interest.


A lot of people may ask, “why are they saying that freelancing is hard and blah blah blah?!” are they intentionally putting a bad light at freelancing?! Of course not! Imagine this, freelancing is like starting your own business online with yourself as the product to be marketed online alongside with a lot of other freelancers (businesses) out there that already had their names and reputations firm to their clients which are your demographic. And since your are just starting, you’re like a small fish thrown in a big sea with other bigger fish for your competition. Yes freelancing might sound new for you but it had really been around for quite some time now. So aside from the dedication and hard work that you put in, if you luckily landed any, getting it in the first place is a whole different story.


Totally agree with these, never really thought that being a freelancer could be hard. The flexibility of your time, unlimited money you could earn for as long as you have projects and clients and so on. But when you jump in without even preparing, you will most likely overwhelm yourself with the things you didn’t prepared. Having some extra funds is surely a great help especially when you are a beginner since you will still build your market. Being patience will come in handy as well because just like any other job or career freelancing can be very stressful also.


The article is very informative. Indeed, freelancing is a serious job that requires dedication in terms of time and effort. It is true that you have to manage on how you can transform into a freelancing job especially if you have a day time job. Freelancing is a great way in order to increase your cash flow but we must ensure on how we can manage to be a good freelancer.


I’m also trying to be a freelancer. Trying to work and earn online with my own pace. When i was just starting, I thought that this is going to be easy just like those people that are inspiring me to do such. Rising all the way to the top is going to be a breeze because if they can, why can’t i?! Right?! Well, that mindset lasted just for a week. Then, after a month, i was really questioning myself what is wrong?! Why am i not getting the traffic/result that I’m expecting?! I’m doing all the best that i can. From the best content that i could think of, to reaching out to people that could help me spread the news about my contents, but still, the traffic was really slow and low. Then reality bit me that this is not going to be the way i want it to be. But i want this that is why I’m still pursuing this path. That is why you should really set your mind that freelancing is just as hard as any other jobs that needs inspiration, dedication and perspiration.


I like the way how you think.I have also good idea which can help to create own freelance network and I hope that it can help to somebody here.Create accounts in the most popular social media sites,then find friends which don some freelance job,join in freelance facebook groups,create own fan page,create facebook freelance group,create website and get some popularity on website to get a lot of visitors,create topics in forums and be connected with users in forums and that is it now we have big freelancer network.


Great article that I am sure a lot of people will learn a lot from. I think one of the most important things to remember is to not quit your main job. Freelancing is not consistent especially at the start so you will definitely need another source of income especially if you have a family to feed. Once you have experience as a freelancer and once you start to make a steady stream of revenue from doing freelancing then you can start to think about quitting your job


Being a freelancer requires more of you than being an employee. You need to be more disciplined and you need to work extra hours. It’s not a 9-5 or less hours job especially when you are trying to build your business.


This article advises that you should not quit your job before becoming a freelancer. I completely disagree. You may have no choice, you may have been fired or downsized. Most of the freelance success stories are of people who did not choose to be freelancers. They simply had no choice. They had to provide for their families really fast.


In this scenario,there is no time to network. They simply have to find clients immediately. My understanding of a network is that it is built over time. My opinion is that a network is for the long run expansion of your business and not really for the short term generation of clients.


I have also tried to freelance while working. I can tell you It’s impossible. You get really tired. Remember the long commutes and the often extra unpaid hours that you need to put in .This rarely leaves you enough time to work on your freelance business.


If you want to be a freelancer, you should


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Faux leather leggings have a much denser fabric, which helps trap heat. These leggings are a sleek addition to your closet, give an edge to your everyday streetwear, and make dressing up easier. Try a monochromatic look and slip on a black chunky knit sweater and trainers. If you’re headed to a party, pumps and a glitter top under a warm faux fur jacket will look glam and keep you toasty.


This one’s for you, diehard gym girls. If you’re brave enough to venture out into the cold and work up a sweat, these leggings from Torrid will keep you cool during your workout. Because of the synthetic fabric, you won’t cool off too quickly when heading home. The cosmic clusters are such a fun pattern and outdo any solid color athletic pants! Add a water bottle and a cute tank, just don’t forget that jacket for the way there and back!


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While these are a bit more expensive, their quality and ability to retain their shape makes them worth it. After a long day or week of wearing them, you won’t have to worry about them bagging around your knees. Their color stays nicely too, even after a few rounds in the washing machine. To style, tuck in a neutral-colored patterned blouse for work and pair with a blazer that cuts in at the waist. Headed to a dinner date after? A black pea coat and chunky black boots are the perfect transition pieces.


The Queen has spoken! We hear that Queen Elizabeth II has finally broken her silence about her grandson Prince Harry's new girlfriend--and her words, luckily, are quite positive.


Us Weekly reported that Her Majesty is "fully supportive" of Harry's relationship with actress Meghan Markle, according to a Buckingham Palace insider.


MUST-SEE: The Very First Photo of Prince Harry and Meghan Markle Is Here, and Princess Diana Would've Adored It


Markle hasn't met Her Majesty yet, but she shouldn't be discouraged―it apparently took Kate Middleton five years before she was introduced to the Queen. And Markle has met plenty of Harry's other royal relatives, including Prince William during a recent trip to London, as well as Harry's father, Prince Charles.


It's been less than a year of the two dating, so Meghan has plenty of time to meet the other ladies in Harry's life--like his famous sis-in-law, Kate Middleton, who just so happens to be Meghan's style twin. Perhaps over the holidays?


Here are my Year 3 Maths teaching resources I would like to share with you. There are lots of different free maths lessons to try. You could use them in the classroom or part of a maths booster course.


Coach Ronald Koeman has Javairô Dilrosun Friday for the first time included in the final selection of the Dutch national team. Orange hits this month, France and Germany in the Nations League.


The twenty-year-old Dilrosun was already the most notable name in the pre-selection that Koeman last week brought out.


The born in Amsterdam, since this season for Hertha BSC in Berlin, where he soon became a rise conquered. The vleugelspeler on two goals and three assists in nine Bundesliga matches.


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It's been an overload of stuff from The Hobbit: The Desolation of Smaug over the past couple days. While we figured the hype had died down for awhile following the release of an extended three-minute trailer yesterday, director Peter Jackson has returned with a new production blog. It's been a few months since the last update, as the last production diary let us know that the film wouldn't be appearing at Comic-Con this year, but this new video makes it worth the wait. The 12th production blog highlights all the pick-up scenes that the cast and crew had to shoot this summer. As always, the best bits come from seeing the actors in full make-up but out of character on the set, and what an incredible set it seems to be. Watch!


As always, the best bits come from seeing the actors in full make-up but out of character on the set, and what an incredible set it seems to be.


What’s the best thing about having a car? Driving of course. And the worst thing? Err, that would be driving as well I suppose.


There are times when I love nothing better than putting the key in the ignition, putting on my sunglasses and hitting the road in search of action, adventure and a playground for my little girl. However, what about those other moments when travelling to work or going for a trip to the local Tesco’s just don’t get the old adrenalin flowing?


Paul Newman is my new hero, and strangely enough he has the same name as one of my old heroes. This one isn’t an actor and racing car driver though; he is a professor in the Department of Engineering Services at Oxford University, which is almost as cool in my books.


Professor Newman (we haven’t yet made it onto first name terms) has created a car which drives itself. It is called Wildcat and has enough cameras, lasers and radars on it to give it all of the tools and the spatial awareness it needs to navigate on its own.


The good people at BAE Systems and Nissan helped put Wildcat together and the aim is to help drivers get back “some of their day”. These cars also communicate with each other to exchange information on traffic jams in the area.


It is kind of hard to imagine being able to relax which the car drives itself, isn’t it? Can you picture yourself nodding off to sleep or playing a game of Scrabble while the vehicle weaves its way through the traffic? Even weirder would be seeing a driverless car heading towards you. I guess it is something which we will all get used to after a while if it really takes off.


This entry was posted in News and Views and tagged car, driverless car, ford, LS, nissan, Oxford University, Paul Newman, Professor Newman, racing car driver by Robert Bell. Bookmark the permalink.<|endoftext|>In today’s internet-driven society, companies that harness technology improve customer relationships,tap new markets, and optimize their outcomes.


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Some have theorized that this upward gaze of Constantine is an indicator of his gradual conversion to Chrisitianity.


Rev: "CONSTANTINI-ANA DAFNE" Victory seated left with her head right holding a palm branch in each hand. A trophey stands in front with a bound captive at her feet.<|endoftext|>“Through divine revelation, riding on a yellow tractor” the Lee Perry Statue will make its grand entrance on earth!


Presspop’s second collaboration with the “Upsetter” is a very special statue, sculpted by master sculptor, Tomohiro Yasui and produced completely in JAPAN by Japanese soft-vinyl craftsmen.


Once again, artist Archer Prewitt has perfectly captured the true essence of Mr.Perry in his younger years, doing his thing in The Black Ark studio.<|endoftext|>395 energy healing for animals a


1256172 s or dementia is our family’s passion. That’s why our assisted living communities have been recognized as the “best of the best” providers in dementia care by Argentum, the nation’s leading senior living professional organization.


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Call us to schedule a visit and to learn more about the individualized care we can offer your loved one at Autumn Leaves of Greenville memory care. It would be our privilege for our family to serve yours.


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The Social Media Marketing Team @Auxano can provide answers to those questions and much more. Here, we explain how Small Businesses can leverage the power of Youtube Social Marketing Platform for displaying their products and services in action while also driving relevant and highly organic website traffic.


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Syrian refugees that reside in Manchester talk to MM about 'death staring at them' in Syria, their 'incredibly dangerous journey' to the UK on boat, and thoughts on UK migration policy.


The refugees feature in a new documentary, named Departing:Arrivals, which shares stories about migrant families that explain their move to the UK and their experiences of raising children in a war-torn territory.


One of the Syrian refugees in the film is a mother in her 30s, with two children aged seven and nine, who found raising them extremely hard under the devastating circumstances they endured.


She told MM: "[Syria] was really bad, death was staring at us all the time, going outside the house is very dangerous, exactly like being inside.


"We were worried about our child’s safety and well being, and it was not easy to get the daily essential needs like food, milk, medicine.


"Having children is a big responsibility in all circumstances, but in the war the responsibility became much harder. When your children’s life depends in you, that puts you in a big pressure.


"When I was there, I couldn’t think of how to raise my child properly, the main thing I could focus on was how to protect him from danger, and how to get his daily essential needs.


"He was always afraid of the voices of the bombs and guns, he couldn’t sleep alone or stay in his room alone even in the day light.


The mother, who has chosen to remain anonymous, has been in the UK for more than a year and a half. Her husband has recently found a job part-time and she continues to go to college.


She went onto explain that the transition from Syria to Manchester was 'painful' but life started to get better after learning the language.


"We left our home, our parents, our friends, our jobs, our streets, our everything and just left to start new life in places that we don’t know.


"We were scared, disappointed, lonely and very sad. Honestly, many times I thought about going back to Syria.


"Now after 20 months nearly, we live in a good house, our children are in the school, my husband and I are learning English in a college and we've started making friends.


"We've started to understand how everything is moving, what to do and where to go when we need something."


When asked about the refugee crisis, she added: "We must live peacefully together on earth and we must help each other.


A father, also in his 30s, described how he sailed across the Mediterranean sea for seven days in an 'incredibly dangerous' venture to escape from Syria.


He told MM: "Our circumstances were extremely hard during the war and conflict. It would be hard for anyone to parent their children and care for them in those terrible circumstances.


"I came to Manchester through the sea on a boat, as I used to work as a seaman. It was an incredibly dangerous journey.


"But I want to make sure it is understood I came for their [his children] safety as some people think we came here for money" he said. "This is so untrue.


"We are just looking for our basic human right which is to raise our children without the constant fear of being bombed or shot at.


"I hate the idea of migration but at the same time the situation we were in left us with no choice but to escape for the safety of our family."


The father has settled in Manchester and volunteers regularly with aid organisations in the city that send support to Europe and Syria.


The film tells the story of his wife's experiences, which explains in detail how they lived through bombings and shootings.


But despite finding refuge in Manchester, they continue to relive the trauma they experienced while in their native country.


"We were in contact with our doctor as my daughter needed help," said the father. "She is struggling emotionally as she has experienced a lot of trauma in Syria.


"But we are grateful to the University of Manchester as they helped us put a letter together to show our GP how much we were struggling with her emotionally.


"We have still not been referred for mental health support but we have been promised we will get an appointment soon.


"We are trying to get used to our new setting, but I can't deny my situation is incredibly challenging.


"I need to improve my English more so I can get a better job and support my family better. Myself, my wife and children are all trying our best to improve."


The director said: "It was a unique privilege to work with these families whose incredible stories of struggle, bravery and sheer will had a profound effect on my understanding of the conflict."


Departing:Arrivals has the parents speaking anonymously about their experiences in order to comfort them.


"[It allowed] me to communicate a much more intimate and honest film, albeit one that took on an stylistically experimental and innovative edge," she said.


Efforts made in producing the film are part of a larger project by the University of Manchester's school of Psychological Sciences.


UoM are attempting to help parents learn new skills to heal mental scars gained by their children during the war and journey to Europe.


Manchester psychologists have been working with a non-governmental organisation called Watan on the Syrian-Turkish border since early on in the conflict.


This is to help distribute support and advice to parents through a daily bread delivery service provided by Khayr Charity Foundation.


An exhibition has been held in Manchester by the psychologists to show distressing hand-drawn pictures created by children of the images they saw in the conflict.


The project is led by Professor Rachel Calam. She said: "Relief efforts naturally focus on alleviating the physical suffering of refugees, but this means that the psychological effects are sometimes neglected.


“Children and their parents can find it hard to cope with the experiences they’ve had and this film is part of a wider attempt to tell that story.


"The parents who spoke to us demonstrate the incredible bravery and determination we’ve come across on countless occasions as refugees fight to keep their families intact and find new lives in safer countries."<|endoftext|>This WeatherCity Weather Forecast for Grandes-bergeronnes, Québec, Canada is computed using a computer-generated forecast model and should be considered experimental. Please confirm this forecast with the forecast issued from your local weather bureau.<|endoftext|>Students, faculty and staff are encouraged to submit an international photo


1256173  was the first time competing in a beauty pageant for many of the contestants. (Supplied: Khris Ginez, Migs Studio Photography)


"They don't promote beauty only, but they also promote eloquence, intelligence, values that can bring social issues to be talked about.


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On 12 August 1986, a deadly cloud of CO2 and water mist was released from Lake Nyos, Cameroon, and killed more than 1700 people by asphyxiation as it spilled into adjacent valleys. The dense cloud of gas, which was 50 m thick and traveled farther than 20 km at speeds of 20 to 50 km/hour, was produced by the dissolution of CO2 in the deep part of the lake; a convective overturn displaced the lower layer of the stratified lake, causing the CO2-rich water that had been at the bottom to degas like a bottle of fizzy water being opened. Such events have happened before in this region, and may happen again if steps are not taken to prevent them.


Schmid et al. report that a similar situation is developing at Lake Kivu, an East African rift lake between Rwanda and the Democratic Republic of Congo. The depths of Lake Kivu are amassing dissolved CO2 and CH4 at a rate fast enough that CH4 concentrations will approach saturation toward the end of this century, making it likely that a magmatic eruption in the volcanically active lake basin, or some other disturbance, could trigger overturn and the release of another lethal CO2 cloud. Without human intervention to reduce the concentration of CH4, the 2 million people along the Lake Kivu shoreline may suffer a catastrophic gas release. — HJS


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1256174  Nobel prize-winning novel by Mikail Sholokov. At 5 1/2 hours long, this love story chronologically centered on the Russian Revolution is probably the most detailed account of Cossack culture that exists cinematically. Grigory Melekhov (Pyotr Glebov) is a Cossack who falls in love with a fellow soldier's wife, Askinia (Elina Bystritskaya), which causes scandal in their small village along the Don River. Askinia's husband repeatedly beats her, and when she becomes pregnant Grigory takes her away, to escape her brutal husband and Grigory's wife by arranged marriage, Nathalia (Zinaida Kiriyenko). When war hits, Grigory is drafted and leaves Askinia to care for the baby, which results in tragedy. World War I and the Bolshevik Revolution take up the bulk of the plot that details the political discrepancies between the Reds and Whites within Russian borders. Quiet Flows the Don, therefore, is as politically enlightening as it is a fascinating look at the Cossacks' rich heritage. Relentlessly slow at times, the film is indicative of the Russian affinity (in literature) for describing the human condition in excruciating detail, as a tragedy that is only sometimes relieved by love. The levels of tragedy in Quiet Flows the Don delve so deep that it is hard to watch, though one feels it worthwhile to persevere for kernels of truth nonetheless. A full DVD of extras, such as interviews with the actors and shorts about Cossack culture, make the 4-disc set feel especially complete.


Return of Frank James: Fabled Missouri outlaw Frank James, brother of the legendary Jesse James straps on his six-shooters and rides out for revenge in director Fritz Lang's The Return of Frank James, the thrilling 1940 sequel to the Western classic Jesse James. From the green Missouri hills to the rugged Rockies their steps are dogged by Frank James, riding hard on the vengeance trail in the wild and woolly era when there was no law for folks except at the end of a gun.


Revenge of the Nerds Special Edition: When lovable nerds Gilbert and Lewis embark on their freshman year at Adams College, little do they realize the perils that await them. They're beset with taunting by the jocks of Alpha Beta fraternity, which only worsens when the jocks accidentally burn down their house and are forced toss the freshmen out of the freshmen dorm. To make matters more problematic, Lewis develops a crush on pretty Betty Childs, popular sorority sister and quarterback's girlfriend. Joined by the aptly named Booger and the violin-playing Pointdexter, the nerds soon realize they must form their own fraternity in self-defense. Soon the tables are turned as the nerds employ high-tech warfare against the jocks.... but can they really win and make a difference?


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Saturday Night Live: Best of Steve Martin 2: Although he was never a cast member on SNL, Steve Martin currently holds the record for number of times hosting the show. From his early days as a stand-up to becoming a household name, Steve Martin has played many memorable and hilarious characters such as "wild and crazy guy", Jorge Festrunk, Theodoric Of York, Tightwad 007, and paid homage to King Tut through song. He also played himself in sketches. Whether peddling a special kind of beauty cream, attempting to renegotiate his contract in the middle of a live show, or doing his infamous banjo-playing monologue with an arrow through his head, Steve Martin is undoubtedly one of the most successful hosts in SNL history.


Solarbabies: In a future in which most water has disappeared from the Earth, we find a group of children, mostly teenagers, who are living at an orphanage, run by the despotic rulers of the new Earth. The group in question plays a hockey based game on roller skates and is quite good. It has given them a unity that transcends the attempts to bring them to heel by the government. Finding an orb of special power, they find it has unusual effects on them. They escape from the orphanage (on skates) and try to cross the wasteland looking for a place they can live free as the stormtroopers search for them and the orb.


South Park:Complete Ninth Season: All fourteen episodes from South Park’s infamous ninth season are now available for the first time in this exclusive 3-disc collector’s set. This season features Kenny’s epic battle between heaven and hell, uprising of redheads and adventures surrounding a certain closet. For these boys, it’s all part of growing up in South Park!


Stargate Atlantis - The Complete Second Season: If Stargate Atlantis isn't the coolest sci-fi series on television, this five-disc, 20-episode box set from the second season (2005-06) offers ample evidence that it's right up there. The writing is good; the stories are intriguing, and the science part of the equation is credible enough to justify our suspension of disbelief. The characters are for the most part well-defined, and the acting, while perhaps not Emmy-caliber, is just fine. The action is exciting, the effects work impressive, the costumes and sets first-rate. But what Atlantis really has going for it is the presence of some of the baddest bad guys in the cosmos: the Wraith. With their flowing white locks, cat-like eyes, pale, almost translucent skin, and teeth so bad they'd make the British blush, the Wraith rock. They also have a constant need to feed--on humans, of course--and are a serious threat not only to Atlantis but to the entire known universe, including good ol' Earth. And although there are occasional diversions, the producers and writers have wisely kept the focus on these implacable antagonists; in fact, the newest member of the team, one Ronon Dex (played by the dreadlocked and hunky Jason Momoa), is a "runner" who escaped the Wraith's clutches, was a fugitive for years before being found by our heroes, and specializes in dispatching the villains with cold precision. In the course of the season, via single episodes and several multi-parters, the Stargate team, commanded by Dr. Elizabeth Weir (Torri Higginson in the show's least interesting role) and led by insouciant Major John Sheppard (Joe Flanigan), with genius-neurotic Dr. Rodney McKay (David Hewlett) handling the scientific intricacies and yet another doc, Carson Beckett (Paul McGillion, affecting a Scottish brogue), overseeing medical matters, deals with the enemy on many fronts. Lt. Ford (Rainbow Sun Francks) defects after assuming Wraith-like characteristics. The team experiments with a "retrovirus" designed to turn Wraiths into humans (the results are decidedly mixed). They encounter a human who raised a Wraith female from childhood and insists she's just like us (she's not). They're captured and imprisoned on a Wraith "hive" ship. And in the final episode, the humans and the Wraiths even form an alliance of supposedly mutual convenience (the episode is a cliffhanger that awaits resolution until Season Three, but anyone who thought this "partnership" was a good idea for our side clearly hasn't been paying attention). As was the case with the Season One set, bonus materials are generous, including audio commentary (by actors, directors, and others) on every episode, various featurettes, photos, and more. Now if only there were a few Wraith interviews...


Stargate Infinity: Adventure Begins: In the near future, a veteran of the Stargate program, four cadets, and a mysterious alien are prevented from returning to Earth by a traitor. The heroes must use the Stargate network to find another way back home while keeping one step ahead of their enemies.


Three Musketeers: A classic tale set during the reign of Louis XIII. A young man joins the musketeers to foil an evil cardinal's plot to seize control of France.


Walkout: From the producer of Selena and directed by award-winning actor Edward James Olmos comes the stirring true story of courage and justice. The year is 1968, the height of the national civil-rights movement. Paula Crisostomo (Alexa Vega, Spy Kids) is an idealistic honor student who refuses to "play it safe" in a school system that discriminates against Mexican-Americans. Together with thousands of supporters, she coordinates a multi-school walkout of students to protest academic prejudices. Mentored by her charismatic teacher Sal Castro (Michael Pena, Million Dollar Baby), and with the help of her friend Bobby (Efran Ramirez, Napoleon Dynamite), Paula learns that sometimes the price of progress is high - but it?s ultimately worth paying.


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1256175  are together, Mauli recalls Chakor and Rajdeep’s warning.While now Mauli takes a shocking decision and comes to Kunal and Nandini who are feeling awkward over thus situation.


Mauli tells Nandini that she trusts her and knows that she can’t do anything wrong with her and hugs her.Mauli also goes to Kunal and hugs him and asks him to not be awkward as he knows that he only loves her.Kunal and Mauli’s Ganesh Mahotsav will bring a drastic storm in their love life when Rajdeep will get Kunal Nandini drugged.


Kunal and Nandini will come together sharing some romantic moments and sensuous dance moves, while her shocked Mauli will eventually be instigated by Rajdeep.And this will now showcase Mauli’s major confrontation to Kunal and Nandini.


Mauli will realize their extramarital affair but as she doesn’t want to lose Kunal or Nandini,Mauli will console Kunal and Nandini instead of bursting her anger on them.Mauli will hug Nandini and Kunal showing her trust on them, while on the other side she gets upset.


Mauli is trying to hide her pain and fear of loosing Kunal and Nandini both, stay tuned for more exciting updates of the upcoming episodes<|endoftext|>In this exciting new management simulation game by Deck13 Hamburg you will start out as the owner of a small logistics company and cleverly employ all of your managerial skills to lead your business to success. Have you ever wanted to found a company in Kansas City? Or are you more the Vegas type? Whether you prefer the Rocky Mountains or New York feel free to live the American Dream on the realistic map of TransRoad: USA. Choose a headquarter in one of 37 real US cities, buy your first trucks and trailers and hire some drivers. Find the best contracts and the best route combinations to avoid unladen journeys and work to your clients’ satisfaction.<|endoftext|>After centuries of neglect, the church is rediscovering the realm of dreams and visions as a legitimate avenue for receiving divine revelation. In Dream Language , James W. Goll provides an insightful and helpful handbook to this fascinating and little-known world. Based on extensive study and filled with personal insights from his years... more...


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