---
license: apache-2.0
pipeline_tag: text-generation
tags:
- biology
---

# InstrcutPLM
InstructPLM is a state-of-the-art protein design model based on [ProGen2](https://www.cell.com/cell-systems/abstract/S2405-4712(23)00272-7) 
and [ProteinMPNN](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997061/) 
and trained on [CATH 4.2](https://www.cathdb.info/) dataset. 
It can design protein sequences that accurately conform to specified backbone structures.
<p align="center">
<img src="https://cdn-uploads.huggingface.co/production/uploads/62a8397d839eeb3ef16a7566/1NRk65EImgBAFgvh8HJrA.png" alt="drawing" width="200"/>
</p>
Please visit our [repo](https://github.com/Eikor/InstructPLM) and [paper](https://github.com/Eikor/InstructPLM) for more information.

Please consider cite our paper and repo: