Doses AI

Open medical intelligence, built to run locally.

Website  ·  Flagship model  ·  Technical report  ·  Runtime

Featured release

Pestle-27B-Ternary-GGUF

A 27B open-weight medical model packaged as an 8.48 GB runnable GGUF. Pestle is designed for private local and on-premises systems spanning clinical knowledge, biomedical evidence work, pharmaceutical retrieval, and coding.

Apache 2.0 · 27B parameters · 8.48 GB GGUF · CPU, Metal and CUDA

Weights and model card · Technical report · Run with mortar.cpp

Research

• Low-bit model compression - ternary and compact representations for capable local models.
• Medical model evaluation - matched benchmarking across clinical knowledge, biomedical QA, retrieval, and general capabilities.
• Local inference - practical execution across CPU, Apple Silicon, and NVIDIA GPUs without a required cloud dependency.

Open source

_{Research preview. Doses AI models are not medical devices and are not intended to replace qualified professional judgment. Contact: malik@doses.ai.}