diff --git "a/generated_eval_predictions.txt" "b/generated_eval_predictions.txt"
new file mode 100644--- /dev/null
+++ "b/generated_eval_predictions.txt"
@@ -0,0 +1,2407 @@
+serious: 1 patientsex: 2 drugs: ALENDRONATE SODIUM, AMITRIPTYLINE, CELECOXIB, GLIMEPIRIDE, HYDROXYZINE PALMITATE, NIACIN, PAROXETINE, SIMVASTATIN reactions: Drug interaction, Memory impairment
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, LISINOPRIL reactions: Intentional overdose, Metabolic acidosis, Shock
+serious: 1 patientsex: 1 drugs: HYDROXOCOBALAMIN reactions: Blood chromaturia, Red urine
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, INFLIXIMAB, MESALAMINE, PREDNISOLONE reactions: Acute respiratory failure, Interstitial lung disease
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CYCLOPHOSPHAMIDE, EPIRUBICIN, PACLITAXEL reactions: Cardiac failure, Cardiac thrombosis, Cardiomegaly, Bundle branch block right, Dyspnoea exertional, Left ventricular hypertrophy, Left atrial thrombosis, Left ventricular dysfunction, Sinus tachycardia, Sinus thrombosis, Sinus thorax, Ventricular hypertrophy
+serious: 1 patientsex: 1 drugs: CEFTAROLINE HYDROCHLORIDE reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: CEFTAZIDIME, FOSCARNET, GANCICLOVIR, VANCOMYCIN reactions: Leukocytoclastic vasculitis, Off label use, Renal impairment
+serious: 1 patientsex: 1 drugs: HYDROXYUREA, IMATINIB reactions: Blast stage leukaemia
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB reactions: Electrolyte imbalance, Skin toxicity
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, DOCETAXEL, DOXORUBICIN, TRASTUZUMAB reactions: Cardiac failure congestive
+serious: 1 patientsex: 2 drugs: CAPECITABINE, EVEROLIMUS, EXEMESTANE, PACLITAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Multiple organ dysfunction syndrome, Septic shock
+serious: 1 patientsex: 2 drugs: FACTOR IX, WARFARIN reactions: Acute myocardial infarction, Ischaemic stroke
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE reactions: Acute kidney injury, Hypercalcaemia, Splenic large B-cell lymphoma
+serious: 1 patientsex: 2 drugs: DOBUTAMINEDOBUTAMINE HYDROCHLORIDE, MITOMYCIN, OCTREOTIDE reactions: Cardiogenic shock, Drug interaction, Drug level increased, Pulmonary oedema, Respiratory failure, Shock
+serious: 1 patientsex: 2 drugs: NAPROXEN reactions: Acute hepatic failure, Eosinophilic pneumonia
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, SIROLIMUS reactions: Anasarca, Acidosis, Drug level above therapeutic, Fluid overload, Hypoventricle dilatation, Mitral valve incompetence, Occipital haematoma, Periventricular enlargement, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ABACAVIR, LAMIVUDINE, LOPINAVIRRITONAVIR reactions: Acute necrotising ulcerative gingivitis
+serious: 1 patientsex: 2 drugs: INFLIXIMAB, METHOTREXATE reactions: Histoplasmosis disseminated, Jaundice cholestatic, Pleural effusion
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, FLUDROCORTISONE reactions: Blood creatinine increased, Hyperkalaemia
+serious: 1 patientsex: 2 drugs: ATROPINE, BOSENTAN, SILDENAFIL reactions: Drug ineffective, Hypertrophic pyloric stenosis
+serious: 1 patientsex: 2 drugs: VALPROIC ACID reactions: Intentional overdose, Suicide attempt, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: BUPIVACAINE, EPINEPHRINE, METHYLPREDNISOLONE reactions: Hypokalaemia
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, CLOBAZAM, CLONAZEPAM, ETOPOSIDE, GABAPENTIN, LACOSAMIDE, LEVETIRACETAM, NITROFURANTOIN, PIGAPENTIN, TOPIRAMATE, VALPROIC ACID reactions: Status epilepticus
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, MEROPENEM, MINOCYCLINEMINOCYCLINE HYDROCHLORIDE, PREDNISOLONE, RIFAMPIN reactions: Histoplasmosis disseminated
+serious: 1 patientsex: 2 drugs: LEVOTHYROXINE, METHIMAZOLE reactions: Gastroschisis, Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 1 drugs: ASPIRIN reactions: Peptic ulcer
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, RANIBIZUMAB reactions: Retinal pigment epithelial atrophy
+serious: 1 patientsex: 1 drugs: LITHIUM reactions: Hypercalcaemia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN reactions: Acute promyelocytic leukaemia
+serious: 1 patientsex: 2 drugs: ANAKINRA, ABATACEPT, ANAKINRA-LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN, ANAKINRA-SODIUM PHOSPHATE, ABATACEPT, ANAKINRA-SODIUM PHOSPHATE, ABATACEPT, ANAKINRA-SODIUM PHOSPHATE, ABATACEPT, ANAKINRA-SODIUM PHOSPHATE, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT, ABA
+serious: 1 patientsex: 2 drugs: DEXTROSE reactions: Endophthalmitis fungal, Posterior hypopyon, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, LEVETIRACETAM, VALPROIC ACID reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM, RIVAROXABAN reactions: Haematuria, International normalised ratio increased
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE, BRENTUXIMAB VEDOTIN reactions: Death, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: OMEPRAZOLE reactions: Anaphylactic reaction, Drug hypersensitivity, Rash
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Calciphylaxis
+serious: 1 patientsex: 2 drugs: CISPLATIN, SUNITINIB MALATE reactions: Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, CRIZOTINIB reactions: Oesophagitis ulcerative
+serious: 1 patientsex: 1 drugs: DEPAMETHASONE, LAMOTRIGINE, PHENOBARBITAL, PHENYTOIN, VALPROIC ACID reactions: Gilberts syndrome, Hyperbilirubinaemia
+serious: 1 patientsex: 1 drugs: LANSOPRAZOLE, TESTOSTERONE, TAMSULOSIN reactions: Aortic stenosis, Hypercalcaemia, Hypervitaminosis A, Myocardial infarction, Renal impairment
+serious: 1 patientsex: 2 drugs: LISINOPRIL reactions: Inappropriate antidiuretic hormone secretion
+serious: 1 patientsex: 1 drugs: INFLIXIMAB reactions: Pulmonary tuberculosis
+serious: 1 patientsex: 2 drugs: USTEKINUMAB reactions: Psoriatic arthropathy
+serious: 1 patientsex: 1 drugs: THIOTINE reactions: Blindness, Optic nerve oedema, Pseudotumour cerebri
+serious: 1 patientsex: 2 drugs: AMIODARONE, DABIGATRAN ETEXILATE MESYLATE, RAMIPRIL reactions: Acute kidney injury, Glomerulonephritis anticoagulant, Haematuria, Hypotension, IgA nephropathy, Perirenal haematoma, Tubulointerstitial nephropathy
+serious: 1 patientsex: 2 drugs: ENTACAPONE, LEVODOPA, PRAMIPEXOLE, SELIGLINE, ZONISAMIDE reactions: Hallucination, auditory
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, ENTECAVIR, LAMIVUDINE, TACROLIMUS reactions: Mucocutaneous tuberculosis
+serious: 1 patientsex: 2 drugs: QUETIAPINE FUMARATE reactions: Aphasia, Intentional product misuse, Intentional product misuse
+serious: 1 patientsex: 1 drugs: ERGOCALCIFEROL, GLIMEPIRIDE, LACTULOSE, METFORMIN HYDROCHLORIDE, PANTOPRAZOLE SODIUM, RIFaxiMIN, SEVELAMER reactions: Hypoglycaemia, Lactic acidosis, Overdose
+serious: 1 patientsex: 1 drugs: METFORMIN HYDROCHLORIDE, PASIREOTIDE, SITAGLIPTIN reactions: Abdominal pain, Diarrhoea, Fatigue, Hypoadrenalism, Hypotension, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, BETAMETHASONE, AMPICILLIN, GENTAMICIN, PENICILLIN G, MAGNESIUM SULFATE reactions: Drug ineffective, Exposure during pregnancy, Neonatal respiratory distress syndrome, Neonatal sepsis, Pneumonia
+serious: 1 patientsex: 1 drugs: BUPIVACAINE, ROPIVACAINE HYDROCHLORIDE reactions: Acute respiratory arrest, Bradycardia, Hypotension, Paralysis, Quadriplegia, Respiratory arrest, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, VINBLASTINE reactions: Chronic heart failure, Cardiomyopathy
+serious: 1 patientsex: 2 drugs: FENTANYL, METHYLENE BLUE, DULOXETINE reactions: Drug interaction, Serotonin syndrome
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, CETUXIMAB, CISPLATIN, DOCETAXEL, FLUOROURACIL, PACLITAXEL reactions: Bone marrow toxicity, Nausea
+serious: 1 patientsex: 1 drugs: ETANERCEPT reactions: Tuberculosis
+serious: 1 patientsex: 1 drugs: CEFUROXIME, GENTAMICIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AMOXICILLIN, LITHIUM, LORAZEPAM, ZIPRASIDONE reactions: Anxiety, Bradykinesia, Drug ineffective, Drug intolerance, Nausea, Tremor
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOCETAXEL, ERLOTINIB, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Disease progression, Ileus, Vomiting
+serious: 1 patientsex: 1 drugs: CHLORPROMAZINE, INSULIN NOS reactions: Neuroleptic malignant syndrome, Thyroid disorder
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOSPORINE, OMEPRAZOLE, PREDNISONE reactions: Sporotrichosis
+serious: 1 patientsex: 2 drugs: PEMBROLIZUMAB reactions: Pneumonitis
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE reactions: Adrenal insufficiency, Diabetes mellitus, Drug ineffective
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, HYDROXYCHLOROQUINE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Aortic aneurysm, Abscess, Aortic rupture, Anaemia, Aortic dissection, Aortic aneurysm, Aortic leakage, Aortic aneurysm, Aortic aneurysm, Aortic aneurysm rupture, Aortic aneurysm, Aortic aneurysm dissection, Aortic aneurysm rupture, Aortic aneurysm ruptured, Aortic aneurysm ruptured, Aortic aneurysm, Aortic rupture, Aortic aneurysm ruptured, Aortic aneurysm, Aortic aneurysm ruptured, Aortic aneurysm, Aortic aneurysm ruptured, Aortic aneurysm, Aortic aneurysm ruptured, Aortic
+serious: 1 patientsex: 1 drugs: BLINATUMOMAB, CASPOFUNGIN, DEXAMETHASONE, MELPHALAN, VORICONAZOLE reactions: Hallucination, Neurotoxicity, Trichosporon infection
+serious: 1 patientsex: 1 drugs: ETOPOSIDE, PREDNISOLONE reactions: Dermatitis spongiform, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: DAPSONE, PREDNISONE, SIROLIMUS, TACROLIMUS reactions: Drug interaction, Hypoxia
+serious: 1 patientsex: 2 drugs: WARFARIN reactions: Herpes zoster, Skin necrosis
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, VINCRISTINE reactions: Acute kidney injury
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, DEXAMETHASONE, VALPROIC ACID reactions: Drug ineffective, Hepatic function abnormal
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, METHOTREXATE, TACROLIMUS reactions: Acute myeloid leukaemia, Condition aggravated, Drug ineffective, Drug resistance, General physical health deterioration, Hallucination, auditory, Hypotension, Respiratory failure, Schizophrenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: DOCETAXEL reactions: Recall phenomenon
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN reactions: Organising pneumonia
+serious: 1 patientsex: 2 drugs: BOZITINIB, FLUVOXAMINE MALEATE, HYDROMORPHONE, NIVOLUMAB, OXYCODONE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: PREDNISONE, VANCOMYCIN reactions: Aortocavitary fistula, Bacteraemia, Cellulitis, Endocarditis, Multiple organ dysfunction syndrome, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: INFLIXIMAB, METHOTREXATE reactions: Hyperglobulinaemia, Leishmaniasis, Pancytopenia
+serious: 1 patientsex: 1 drugs: AMIKACIN, AMPHOTERICIN B, CASPOFUNGIN, CLARITHROMYCIN, CIPROFLOXACIN, DOXYCYCLINE, LINEZOLID, MEROPENEM, METHYLPREDNISOLONE, RIFAMPIN, VORICONAZOLE reactions: Drug ineffective, Multiple organ dysfunction syndrome, Off label use
+serious: 1 patientsex: 2 drugs: DOCETAXEL, PALBOCICLIB reactions: Clostridium septicum infection, Multiple organ dysfunction syndrome, Septic shock
+serious: 1 patientsex: 2 drugs: ALCOHOL, OLANZAPINE reactions: Hyponatraemia, Overdose, Somnolence
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, GLIMEPIRIDE, METFORMIN HYDROCHLORIDE, RAMELTON, SITAGLIPTIN, SORAFENIB, ZOLPIDEM TARTRATE reactions: Anaemia, Diarrhoea haemorrhagic, Hepatocellular carcinoma, Intestinal infiltration, Tarry stools
+serious: 1 patientsex: 2 drugs: PREDNISONE, SOLUMERIDE reactions: Nocardiosis
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN reactions: Neutropenia, Pancytopenia, Rash
+serious: 1 patientsex: 2 drugs: OMEPRAZOLE, PREDNISONE, SIROLIMUS, TACROLIMUS reactions: Ascites, Gastrointestinal angioedema
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, ECULIZUMAB, HYDRALAZINE HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Acute kidney injury, Atypical haemolytic uraemic syndrome, Haemolytic anaemia, Haemolytic anaemia, Haemolytic anaemia, Haemolytic anaemia, Oliguria, Renal failure, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, COLCHICINE, CLOPIDOGREL BISULFATE, DOXAZOSINDOXAZOSIN MESYLATE, FLUTICASONE, METOPROLOL, TORSEMIDE, VITAMIN D NOS, XARELTO reactions: Insulin autoimmune syndrome
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Inappropriate antidiuretic hormone secretion
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Mucormycosis
+serious: 1 patientsex: 1 drugs: AMIKACIN, CYTARABINE, LEVOFLOXACIN, MEROPENEM, MICAFUNGIN SODIUM, VANCOMYCIN reactions: Drug ineffective, Pneumonia stomatotrophomonas
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, VINBLASTINE reactions: Nephropathy toxic
+serious: 1 patientsex: 2 drugs: MYCOPHENOLIC ACID, PREDNISONE reactions: Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 2 drugs: BACLOFEN, ETORICOXIB, FENTANYL, PROPOFOL, ROCURONIUM BROMIDE, SEVOFLURANE, TRIAZOLAM reactions: Delirium
+serious: 1 patientsex: 2 drugs: RANIBIZUMAB reactions: Vitreous haemorrhage
+serious: 1 patientsex: 2 drugs: CEPHALEXIN, ERTAPENEM SODIUM reactions: Off label use
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYTARABINE, DEXAMETHASONE, RITUXIMAB reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: LETROZOLE reactions: Abortion spontaneous, Maternal exposure before pregnancy
+serious: 1 patientsex: 2 drugs: MESALAMINE reactions: Eosinophilic pneumonia, Organising pneumonia
+serious: 1 patientsex: 2 drugs: TAMOXIFEN reactions: Endometrial stromal cell, Leiomyoma
+serious: 1 patientsex: 1 drugs: INDAPAMIDE, METFORMIN HYDROCHLORIDE, PERINDOPRIL, SITAGLIPTIN reactions: Megaloblastic anaemia
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: ACITRETIN, CLOBETASOL PROPIONATE, METHOTREXATE, MINOCYCLINE HYDROCHLORIDE, PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: LEUPROLIDE ACETATE, MEDROXYPROGESTERONE reactions: Vaginal haemorrhage
+serious: 1 patientsex: 1 drugs: LAMOTRIGINE, METFORMIN HYDROCHLORIDE, METOPROLOL, PREGABALIN, QUETIAPINE, VENLAFAXINE HYDROCHLORIDE reactions: Coma, Hypotension, Intentional overdose, Respiratory failure, Suicide attempt, Tachycardia
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Angioedema
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, METHYLPREDNISOLONE reactions: Acute respiratory failure, Respiratory tract infection
+serious: 1 patientsex: 2 drugs: ALPRAZOLAM, ACYCLOVIR, CEFTRIAXONE, DEXAMETHASONE, FENTANYL, MIDAZOLAM HYDROCHLORIDE, LORAZEPAM, MIDAZOLAM HYDROCHLORIDE, VANCOMYCIN reactions: Drug dependence, Drug withdrawal syndrome, Drug dependence
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, NIVOLUMAB, PREDNISONE reactions: Colitis, Drug intolerance, Haematochezia, Pneumoperitoneum
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, ACETAMINOPHENHYDROCORTISONE, ISONIAZID, LEVOFLOXACIN, MEROPENEM, POTASSIUM, PYRAZINAMIDE, RIFAMPIN, STREPTOMYCINSTREPTOMYCIN SULFATE reactions: Hypoglycaemia, Hyponatraemia, Off label use, Pyrexia, Respiratory failure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, IFOSFAMIDE, VINCRISTINE reactions: Fungal infection, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: CYTARABINE, IDARUBICIN reactions: Acute respiratory distress syndrome, Immune reconstitution inflammatory syndrome, Septic shock
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, RITUXIMAB reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Condition aggravated, Infection, Streptococcal infection
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, DEXAMETHASONE, RANIBIZUMAB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: PREDNISOLONE reactions: Septic shock
+serious: 1 patientsex: 1 drugs: TRIAMCINOLONE ACETONIDE reactions: Endophthalmitis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, FLUDARABINE PHOSPHATE, IMATINIB, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Diffuse large B-cell lymphoma, Richters transformation
+serious: 1 patientsex: 1 drugs: ASPIRIN, BUDESONIDE, CYCLOPHOSPHAMIDE, HYDROCORTISONE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: BLINATUMOMAB, CYCLOPHOSPHAMIDE, DEXAMETHASONE, INOTUZUMAB, MERCAPTOPURINE, METHOTREXATE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Abdominal pain, Nausea, Recurrent lymphoma
+serious: 1 patientsex: 2 drugs: AMRUBICIN, CARBOPLATIN, CISPLATIN, ETOPOSIDE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CISPLATIN, ENOXAPARIN, ETOPOSIDE, HYDROCORTISONE, IRON, METOCLOPRAMIDE, ONDANSETRON reactions: Anaemia, Dysphagia, Odynophagia, Oral mucosal inflammation, Oral dermatitis, Foetal exposure during pregnancy, Odynophagia, Oral mucosal inflammation, Oral dermatitis, Oral mucosal inflammation, Oral dermatitis, Premature baby, Premature delivery, Vomiting
+serious: 1 patientsex: 1 drugs: CISPLATIN, ETOPOSIDE, IRINOTECAN reactions: Hepatic encephalopathy, Jaundice
+serious: 1 patientsex: 2 drugs: MELPHALAN reactions: Metastases to pelvis
+serious: 1 patientsex: 2 drugs: LEVETIRACETAM, VALPROIC ACID reactions: Myoclonus, Off label use, Seizure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOCETAXEL, DOXORUBICIN HYDROCHLORIDE, EPIRUBICIN, FLUTICASONE PROPIONATE reactions: Cardiac failure, Cardiomyopathy
+serious: 1 patientsex: 2 drugs: METHYLDOPA reactions: Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: CETIRIZINE HYDROCHLORIDE, EPINEPHRINE, FAMOTIDINE, FexOFENADINE, DIPHENHYDRAMINE, LORATADINE, OMALIZUMAB reactions: Anaphylactic reaction, Cardiac arrest
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, CYCLOSPORINE, METHYLPREDNISOLONE, MEROPENEM, METHYLPREDNISOLONE SODIUM SUCCINATE, PREDNISOLONE reactions: Bronchiectasis, Bronchopulmonary aspergillosis, Drug ineffective, Interstitial lung disease, Pulmonary necrosis, Respiratory failure, Respiratory failure, Sputum exfiltration
+serious: 1 patientsex: 2 drugs: SORAFENIB, VINORELBINE TARTRATE reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: DENOSUMAB, IPILIMUMAB, NIVOLUMAB, PREDNISOLONE, TRAMETHINIB reactions: Iridocyclitis, Rash
+serious: 1 patientsex: 1 drugs: MELPHALAN reactions: Myelodysplastic syndrome
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, LOSARTAN reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: BASILIXIMAB, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Meningitis cryptococcal, Fungaemia
+serious: 1 patientsex: 1 drugs: METFORMIN HYDROCHLORIDE reactions: Lichen planus
+serious: 1 patientsex: 1 drugs: HYDROCHLOROTHIAZIDETELMISARTAN reactions: Urticarial vasculitis
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, CISPLATIN, CYCLOPHOSPHAMIDE, DEXAMETHASONE, EPIRUBICIN, ETOPOSIDE, LENALIDOMIDE reactions: Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: LANREOTIDE, TEMOZOLOMIDE reactions: Bone pain, Bone marrow failure, Fatigue, Nausea, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: AMOXICILLIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Neuropathy peripheral, Neutropenia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYCLOSPORINE, FLUOROURACIL, METHOTREXATE reactions: Acute myeloid leukaemia, Cytopenia, Dermatitis exsudative, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous, Dermatitis bullous
+serious: 1 patientsex: 2 drugs: PEGINTERFERON ALFA-2B, RIBAVIRIN reactions: Hepatitis C, Treatment failure
+serious: 1 patientsex: 1 drugs: ATORVASTATIN, BISOPROLOL, IBUPROFEN, WARFARIN reactions: Confusional state, Inappropriate antidiuretic hormone secretion
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, EPIRUBICIN, ETOPOSIDE, GESTODONE, IFOSFAMIDE reactions: Inferior vena cava syndrome
+serious: 1 patientsex: 1 drugs: GANCICLOVIR, VALGANCICLOVIR reactions: Toxic encephalopathy
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOCETAXEL reactions: Diarrhoea, Diarrhoea cholestatic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic, Diarrhoea haemorrhagic,
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, INFLIXIMAB, METHADNONE, PREDNISONE reactions: Abdominal pain, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal wall bruising, Abdominal pain upper, Abdominal wall stenosis, Abdominal pain upper, Abdominal wall oedema, Abdominal pain upper, Abdominal wall bruising, Abdominal pain upper, Abdominal wall oedema, Abdominal wall bruising, Abdominal pain upper, Abdominal wall oedema, Abdominal wall bruising, Abdominal wall oedema, Abdominal wall oedema, Abdominal wall stenosis, Abdominal wall oedema, Abdominal wall bruising, Abdominal wall oedema, Abdominal wall oedema, Abdominal wall stenosis, Abdominal wall oedema, Abdominal wall oe
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB reactions: Posterior vitreous haemorrhage
+serious: 1 patientsex: 1 drugs: GEMCITABINEGEMCITABINE HYDROCHLORIDE, VALPROIC ACID reactions: Febrile neutropenia, Lymphocytopenia, Myelosuppression
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PACLITAXEL reactions: Anaemia, Neuropathy peripheral
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE reactions: Dermatomyositis
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, BISOPROLOL, CYAMEMAZINE, LERCANIDIPINE, METFORMIN HYDROCHLORIDE, ZUCLPENTHIXOL ACETATE reactions: Accidental overdose, Drug administration error, Hypotension, Neuroleptic malignant syndrome, Suicide attempt
+serious: 1 patientsex: 2 drugs: ERLOTINIB reactions: Delusional ideation, Delusion, Hallucination, Lacunar infarction, Memory impairment, Sluggishness
+serious: 1 patientsex: 1 drugs: ASPARAGINASE, CYCLOPHOSPHAMIDE, METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Epstein-Barr virus infection, Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, LEVOTHYROXINE, METOPROLOL, VALPROIC ACID reactions: Ammonia increased, Aggression, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Ag
+serious: 1 patientsex: 1 drugs: IVERMECTIN reactions: Blindness, Bradycardia, Generalised tonic-clonic seizure, Mydriasis, Optic nerve haemorrhage, Seizure, Vision blurred
+serious: 1 patientsex: 2 drugs: ESTRADIOL, PROGESTERONE reactions: Adrenal adenoma, Cushings syndrome, Drug ineffective, Virilisation
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, AMPHOTERICIN C, FLUCONAZOLE, FLUCONAZOLE SODIUM, GENTAMICIN, RITUXIMAB, TACROLIMUS, VANCOMYCIN reactions: Bacteraemia, Drug ineffective, Lethargy, Pyrexia, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: ASPIRIN reactions: Retinopathy
+serious: 1 patientsex: 2 drugs: ASPIRIN, CEFEPIME HYDROCHLORIDE, DAPTOMYCIN, INSULIN NOS, METOPROLOL SUCCINATE, PANTOPRAZOLE SODIUM, PRASUGREL, LISINOPRIL, METOPROLOL SUCCINATE, PRASUGREL HYDROCHLORIDE, PRASUGREL BISULFATE reactions: Acute kidney injury, Confusional state, Drug ineffective, Drug interaction, Toxic encephalopathy
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, FENTANYL, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, PRILOCAINE, TRAMADOL reactions: Constipation, Delirium, Drug ineffective, Somnolence
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, METHYLPREDNISOLONE, REMDESIVIR reactions: Electrocardiogram QT prolonged, Sinus bradycardia
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, VINBLASTINE reactions: Arthralgia, Pharyngitis viral, Synovitis
+serious: 1 patientsex: 2 drugs: CILASTATIN SODIUMIMIPENEM, FENTANYL CITRATE, HYDROMORPHONE HYDROCHLORIDE, LISINOPRIL, MIDAZOLAM HYDROCHLORIDE, MICAFUNGIN SODIUM, ONDANSETRON, OLANZAPINE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM S
+serious: 1 patientsex: 2 drugs: ALENDRONATE SODIUM reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, FUROSEMIDE, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, METHOTREXATE, METHYLPREDNISOLONE, THYMOCYTE IMMUNE GLOBULIN NOS reactions: Acute graft versus host disease in gastrointestinal tract, Acute graft versus host disease in liver, Graft versus host disease in hepatic axis, Neutropenic colitis, Oral mucosal inflammation, Pneumonia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: PHENYTOIN reactions: Fall, Pneumonia aspiration, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: DOXYCYCLINE reactions: Drug hypersensitivity, Drug hypersensitivity, Nausea
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, FLUDARABINE PHOSPHATE, MYCOPHENOLATE MOFETIL, THIOTEPA, TREOSULFAN reactions: Arterial hypertension, Neurotoxicity
+serious: 1 patientsex: 1 drugs: DENOSUMAB, IPILIMUMAB, NIVOLUMAB reactions: Autoimmune thyroiditis, Colitis, Diarrhoea, Diabetes mellitus, Hepatitis, Hyperglycaemia, Ketoacidosis, Immune-mediated diabetes mellitus, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune-mediated thyroiditis, Immune-mediated hepatitis, Immune
+serious: 1 patientsex: 2 drugs: CAPECITABINE, CYCLOPHOSPHAMIDE, DOCETAXEL, DOXORUBICIN, ERIBULIN, FLUOROURACIL, LEUPROLIDE ACETATE, TAMOXIFEN, ZOLEDRONIC ACID reactions: Drug ineffective, Pulmonary artery thrombosis, Respiratory failure
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Immune thrombocytopenic purpura
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Drug resistance, Stent thrombosis
+serious: 1 patientsex: 1 drugs: ENOXAPARIN, HYDROXYCHLOROQUINE, LOSARTAN, LOPINAVIRRITONAVIR, OXYGEN, RIVAROXABAN reactions: Pulmonary embolism
+serious: 1 patientsex: 2 drugs: CAPECITABINE, LAPATINIB reactions: Dermatomyositis
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, DEXAMETHASONE, METHYLPREDNISOLONE, MOMETASONE FUROATE, PREDNISOLONE, SODIUM CHLORIDE, TRIAMCINOLONE reactions: Drug interaction, Hypersensitivity, Urticaria
+serious: 1 patientsex: 1 drugs: ALEMTUZUMAB, CYCLOSPORINE, DEXAMETHASONE, ETOPOSIDE, HUMAN IMMUNOGLOBULIN G, NITROMANTINE, RITUXIMAB, VANCOMYCIN reactions: Acute kidney injury, Hyperkalaemia, Lactic acidosis, Multiple organ dysfunction syndrome, Septic shock
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, CLOBAZAM, LEVETIRACETAM, PERAMPANEL reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, AMIKACIN, MORPHINE SULFATE, PROTHROMBIN reactions: Acute kidney injury, Renal pseudoaneurysm ruptured, Renal parenchymal haematoma
+serious: 1 patientsex: 2 drugs: CYTARABINE, DEXAMETHASONE, METHOTREXATE, PREDNISOLONE reactions: Decreased appetite, Decreased appetite, Decreased appetite, Gait disturbance, Myelopathy, Myopathy, Paraparesis, Vitamin B12 decreased, Vitamin C decreased, Vitamin D decreased
+serious: 1 patientsex: 2 drugs: CAPECITABINE, CARBOPLATIN, DOCETAXEL, LAPATINIB, PERTUZUMAB, TRASTUZUMAB reactions: Disease progression
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Diarrhoea, Fatigue, Nausea, Palmar-plantar erythrodysaesthesia syndrome, Retinal tear, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, IFOSFAMIDE, NIVOLUMAB, PACLITAXEL reactions: Disease progression
+serious: 1 patientsex: 2 drugs: MEDROXYPROGESTERONE ACETATE reactions: Arthritis, Disease recurrence, Lymph node enlargement, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: BOSENTAN, FUROSEMIDE, SILDENAFIL reactions: Ascites, Central venous thrombosis, Intestinal obstruction, Pleural effusion, Respiratory tract infection, Scoliosis, Stomatitis, Treatment failure
+serious: 1 patientsex: 1 drugs: ARSENTIX, CYTARABINE, IDARUBICIN, TRETINOIN reactions: Acute myeloid leukaemia recurrent, Myelitis
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOBUTAMINEDOBUTAMINE HYDROCHLORIDE, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, MYCOPHENOLIC ACID, PREDNISONE, SOLUMERIDE reactions: Drug ineffective, Drug resistance, Off label use
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, GLIMEPIRIDE, METFORMIN HYDROCHLORIDE, SPIRONOLACTONE, TELMISARTAN, VORICONAZOLE reactions: Hypercalcaemia, Hyperkalaemia, Proteinuria, Quadriparesis
+serious: 1 patientsex: 1 drugs: FENTANYL, HYDROMORPHONE, PROPOFOL, ROCURONIUM BROMIDE reactions: Respiratory depression
+serious: 1 patientsex: 2 drugs: DICLOFENAC SODIUM reactions: Embolia cutis medicamentosa
+serious: 1 patientsex: 2 drugs: ASPIRIN, BISOPROLOL, CALCIUM CARBONATE, CHOLECALCIFEROL, CHOLECALCIFEROL SODIUM, CHOLECALCIFEROL HYDROCHLORIDE, CYCLOSPORINE, HYDROCORTISONE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLORO
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE, FLUPHENAZINE ENTHASETATE, HALOPERIDOL, SERTRALINE HYDROCHLORIDE reactions: Multiple system atrophy
+serious: 1 patientsex: 2 drugs: AMANTADINE HYDROCHLORIDE, CARBIDOPALEVODOPA, ENTACAPONE, PRAMIPEXOLE, ROPINEROLE, TOLCAPONE reactions: Drug intolerance, Parkinsons disease
+serious: 1 patientsex: 2 drugs: TREPROSTINIL reactions: Gastrointestinal disorder
+serious: 1 patientsex: 2 drugs: AXITINIB, PEMBROLIZUMAB reactions: Haematuria
+serious: 1 patientsex: 1 drugs: LENVATINIB reactions: Pneumothorax
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, BENDROFLUMETHIAZIDE, CETIRIZINE HYDROCHLORIDE, DICLOFENAC, HYDROCORTISONE, IBUPROFEN, METFORMIN HYDROCHLORIDE, PAROXETINE, RAMIPRIL, SIMVASTATIN, TOPIRAMATE reactions: Adrenal insufficiency, Drug interaction, Drug level decreased, Drug level increased, Drug interaction, Drug level decreased, Fatigue, Hypertension, Osteopenia, Osteopenia, Osteopenia fracture, Osteopenia, Osteopenia, Osteopenia, Osteopenia fracture, Osteopenia, Osteopenia fracture, Osteopenia, Osteopenia fracture, Osteopenia fracture, Osteopenia fracture, Osteopenia fracture, Osteopenia fracture, Osteopenia fracture, Osteopenia fracture, Osteopenia
+serious: 1 patientsex: 2 drugs: ASPIRIN reactions: Gallbladder rupture
+serious: 1 patientsex: 1 drugs: MEROPENEM reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: DIGOXIN, FUROSEMIDE, INSULIN NOS, METHIMAZOLE, RAMIPRIL, PROPRANOLOL HYDROCHLORIDE reactions: Agranulocytosis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Crohns disease
+serious: 1 patientsex: 2 drugs: CAPECITABINE, LOVASTATIN reactions: Dysaesthesia, Nail toxicity, Onychomadesis
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALENDRONIC ACID reactions: Ulna fracture
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, ETOPOSIDE, FLUDARABINE PHOSPHATE, LINEZOLID, METHOTREXATE, TACROLIMUS, VANCOMYCIN reactions: Cytomegalovirus meningitis, Enterococcal infection, Haemophagocytic syndrome, Meningitis viral, Meningitis viral reactivation, Sepsis
+serious: 1 patientsex: 2 drugs: EFAVIRENZ, LAMIVUDINE, TENOFOVIR DISOPROXIL FUMARATE reactions: Aplasia cutis congenita
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, MEROPENEM reactions: Burkholderia pseudomallei infection, Drug ineffective
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB, VALPROIC ACID reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: DACTINOMYCIN, ETOPOSIDE, IFOSFAMIDE, VINCRISTINE reactions: Acute hepatic failure, Acute kidney injury, Disseminated intravascular coagulation, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, LEVOFLOXACIN, ANASTROVOL reactions: Drug ineffective, Pulmonary cryptococcosis
+serious: 1 patientsex: 2 drugs: DOXYCYCLINE reactions: Antineutrophil cytoplasmic antibody positive vasculitis
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOCETAXEL, ERIBULIN reactions: Malignant neoplasm progression
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE reactions: Condition aggravated, Drug ineffective, Tachycardia
+serious: 1 patientsex: 1 drugs: GENTAMICIN reactions: Renal failure
+serious: 1 patientsex: 1 drugs: METFORMIN HYDROCHLORIDE reactions: Toxic encephalopathy
+serious: 1 patientsex: 1 drugs: MACITENTAN, RIOCIGUAT reactions: Drug interaction, Pulmonary arterial hypertension
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 2 drugs: FINGOLIMOD reactions: Disease rebound
+serious: 1 patientsex: 2 drugs: DISOPYRAMIDE reactions: Cardiogenic shock, Depressed level of consciousness, Drug level increased, Overdose, Ventricular tachycardia
+serious: 1 patientsex: 2 drugs: CAPECITABINE reactions: Breast cancer metastatic
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Aphthous ulcer, Gastritis, Immune-mediated enterocolitis, Oesophagitis
+serious: 1 patientsex: 1 drugs: CAPECITABINE reactions: Dehydration, Dehydration, Electrolyte imbalance, Erythrodysaesthesia, Haematuria, Palmar-plantar erythrodysaesthesia syndrome, Peripheral dehydration, Skin exfoliation, Skin ulcer
+serious: 1 patientsex: 2 drugs: CLOBAZAM, TOPIRAMATE, VALPROIC ACID reactions: Status epilepticus
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, IRINOTECAN, LOMUSTINE, TEMOZOLOMIDE reactions: Glioblastoma
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN reactions: Peritonitis bacterial
+serious: 1 patientsex: 1 drugs: LEVOFLOXACIN reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: CAPECITABINE, CISPLATIN, DOCETAXEL reactions: Clostridium difficile colitis, Febrile neutropenia
+serious: 1 patientsex: 2 drugs: CLOZAPINE, HALOPERIDOL, OLANZAPINE, RISPERIDONE reactions: Drug ineffective, Hepatotoxicity, Pleural effusion
+serious: 1 patientsex: 1 drugs: CAPECITABINE, CISPLATIN, DOCETAXEL, FLUOROURACIL reactions: Bone marrow failure
+serious: 1 patientsex: 2 drugs: ASPIRIN, CYTARABINE, DAUNORUBICIN reactions: Febrile neutropenia, Myocarditis
+serious: 1 patientsex: 1 drugs: CLOZAPINE, TOPIRAMATE reactions: Agranulocytosis, Drug interaction, Neutropenia
+serious: 1 patientsex: 1 drugs: HYDRALAZINE HYDROCHLORIDE, ISOSORBIDE DINITRATE reactions: Hypotension
+serious: 1 patientsex: 1 drugs: CHLODRIDAZEPOXIDE, LACTULOSE reactions: Hepatic encephalopathy, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Cholecystitis acute, Enterovirus infection, Hepatitis fulminant, Multiple organ dysfunction syndrome, Sepsis
+serious: 1 patientsex: 2 drugs: CLARITHROMYCIN, ENOXAPARIN, WARFARIN reactions: Drug interaction, International normalising ratio decreased, Pulmonary embolism
+serious: 1 patientsex: 2 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, PREDNISOLONE reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 2 drugs: CAPECITABINE, DENOSUMAB, DOCETAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE, LAPTANIB, PERTUZUMAB, ZOLEDRONIC ACID reactions: Disease progression
+serious: 1 patientsex: 2 drugs: TAZOCIN reactions: Off label use
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PACLITAXEL reactions: Palmar-plantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 1 drugs: CASPOFUNGIN, CILASTATIN SODIUMIMIPENEM, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, SULFAMETHOXAZOLETRIMETHOPRIM, TEICOPLANIN, TACROLIMUS reactions: Candida infection, Fungal infection, Multiple organ dysfunction syndrome, Pneumonia, Sepsis, Trichosporon infection
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, CEFTRIAXONE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Acute kidney injury, Endocarditis, Lactic acidosis, Pulmonary hypertension, Septic shock, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Alopecia universalis, Alopecia areata
+serious: 1 patientsex: 1 drugs: APIXABAN, ASPIRIN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, DOBUTAMINEDOBUTAMINE HYDROCHLORIDE, FUROSEMIDE, LEVOFLOXACIN, PRASUGREL, PREDNISOLONE, REPAGLINIDE, TENELIGLIPTIN reactions: Acute kidney injury, Nocardiosis, Prostatic abscess
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Erythema multiforme, Pancytopenia, Stomatitis
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, HYDROCHLOROTHIAZIDE, LOSARTAN reactions: Lupus-like syndrome
+serious: 1 patientsex: 1 drugs: LEFLUNOMIDE, METHOTREXATE reactions: Mycoplasmal pneumonia, Legionella infection
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Adrenal insufficiency, Coagulopathy, Hepatic steatosis, Hepatic failure, International normalised ratio increased
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Diffuse large B-cell lymphoma, Epstein-Barr virus infection, Intestinal perforation, Lymphadenectasis, Pleural effusion, Pleural effusion, Pyrexia, Splenomegaly, Stomatitis
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CISPLATIN, PACLITAXEL, URSODIOL reactions: Bacteraemia, Cholangitis sclerosing
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, CISPLATIN, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, MESNA, VINCRISTINE reactions: Bone marrow failure, Neutropenia
+serious: 1 patientsex: 1 drugs: NATALIZUMAB reactions: Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 2 drugs: CYCLOBENZAPRINE, FLUOXETINE HYDROCHLORIDE, HYDROCODONE reactions: Adrenal insufficiency, Adrenal suppression, Colitis microscopic, Drug ineffective, Fatigue, Hyperhidrosis, Muscle spasms, Muscle twitching, Muscle spasms, Muscle twitching, Muscle spasms, Muscle twitching, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Mus
+serious: 1 patientsex: 2 drugs: ASPIRIN, HUMAN IMMUNOGLOBULIN G, METILPRREDNISOLONE, PREDNISONE reactions: Drug ineffective, Treatment failure
+serious: 1 patientsex: 1 drugs: CLONAZEPAM reactions: Drug-induced liver injury, Hyperglycaemic crisis, Hepatic function abnormal
+serious: 1 patientsex: 1 drugs: CISPLATIN, VINORELBINEVINORELBINE TARTRATE reactions: Colitis ulcerative
+serious: 1 patientsex: 2 drugs: AFLIBERCEPT, HEPARIN SODIUM, RANIBIZUMAB reactions: Retinal artery occlusion
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, WARFARIN reactions: Atrial thrombosis, Device complication, Drug intolerance, Fall, Haemorrhage intracranial, Subarachnoid haemorrhage
+serious: 1 patientsex: 1 drugs: IPILIMUMAB reactions: Anaemia, Acute kidney injury, Proteinuria, Nephrotic syndrome, Interstitial nephritis, Proteinuria, Synovitis
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Stress cardiomyopathy
+serious: 1 patientsex: 2 drugs: PHENYTOIN reactions: Purple glove syndrome
+serious: 1 patientsex: 2 drugs: ONDANSETRON HYDROCHLORIDE reactions: Dermatitis hyperpigmentative
+serious: 1 patientsex: 2 drugs: MESALAMINE reactions: Eosinophilic bronchitis
+serious: 1 patientsex: 2 drugs: AMANTADINE HYDROCHLORIDE, CARBIDOPALEVODOPA, PRAMIPEXOLE, ROTIGOTINE, ROTIGOTINE reactions: Hallucination, Parkinsons disease, Suicide attempt
+serious: 1 patientsex: 1 drugs: LINEZOLID, RIFAMPIN, VANCOMYCIN reactions: Acute kidney injury, Candida infection, Pneumonia, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, ASPIRIN, BUDESONIDE, CYCLOPHOSPHAMIDE, CYTARABINE, METHYLPREDNISOLONE, PREDNISONE, TOFACITINIB CITRATE, VINCRISTINE reactions: Drug ineffective, Herpes zoster
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, DEXMEDETOMIDINE, FLUMAZENIL, MIDAZOLAM HYDROCHLORIDE, PROPOFOL reactions: Agitation, Drug interaction, Drug withdrawal syndrome, Delirium, Intentional product misuse, Psychotic disorder, Pulse absent
+serious: 1 patientsex: 1 drugs: FINGOLIMOD HYDROCHLORIDE reactions: Fall, Cryptococcal cutaneous infection, Loss of consciousness, Rash maculo-papular, Varicella zoster virus infection
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, POSACONAZOLE reactions: Haemorrhage, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE reactions: Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRIDOXINE, RIFAMPIN reactions: Cerebral tuberculoma, Hemiparesis
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, METHYLPREDNISOLONE, PREDNISOLONE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, ALEMTUZUMAB, CYCLOSPORINE, METHOTREXATE, MYCOPHENOLATE MOFETIL reactions: Gamma-herpesvirus infection, Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 1 drugs: APIXABAN, DILTIAZEM, METOPROLOL, VALPROIC ACID reactions: Bradycardia, Drug ineffective
+serious: 1 patientsex: 1 drugs: ANAKINRA, METHYLPREDNISOLONE, HEPARIN SODIUM, LOPINAVIRRITONAVIR reactions: Off label use
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE, TACROLIMUS reactions: Acute kidney injury, Chronic kidney disease, Hepatic fibrosis, Hepatic function abnormal, Portal fibrosis
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, DAPSONE, CYCLOSPORINE, INFLIXIMAB, METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Drug ineffective, Drug resistance
+serious: 2 patientsex: 2 drugs: ONDANSETRON reactions: Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: CISPLATIN, DEXAMETHASONE, GEMCITABINE HYDROCHLORIDE, PALONOSETRON reactions: Erythema, Pain, Skin necrosis
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB reactions: Cholangitis, Drug ineffective, Off label use, Product use in unapproved indication
+serious: 2 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: AMIKACIN, AMOXICILLINCLAVULANIC ACID, CYCLOSERINE, CLARITHROMYCIN, ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, MOXIFLOXACIN, PYRAZINAMIDE, RIFAMPIN, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Depression, Drug resistance
+serious: 2 patientsex: 1 drugs: DORZOLAMIDETIMOLOL, IBUPROFEN, LIRAGLUTIDE, LORCASERIN, LOTEPREDNOL, PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: TERBINAFINE reactions: Acute kidney injury
+serious: 1 patientsex: 2 drugs: LOPERAMIDE HYDROCHLORIDE reactions: Cardiac arrest, Drug abuse, Overdose, Torsade de pointes, Ventricular fibrillation
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, IMIDAPRIL, GLIMEPIRIDE, METFORMIN HYDROCHLORIDE, IPRAGLIFLOZIN, OMEPRAZOLE, TAMSULOSIN HYDROCHLORIDE, VALACYCLOVIR HYDROCHLORIDE reactions: Abdominal pain, Aspartate aminotransferase increased, Blood glucose increased, Blood bilirubin decreased, Blood glucose increased, Blood urea increased, Blood pressure increased, Blood glucose decreased, Blood glucose increased, Blood glucose increased, Blood urea increased, Blood pressure decreased, Blood glucose increased, Blood glucose decreased, Blood pressure increased, Blood glucose increased, Blood glucose decreased, Blood pressure systolic increased, Blood glucose increased, Blood glucose increased, Blood pressure systolic decreased, Blood glucose increased, Blood glucose increased, Blood glucose decreased, Blood pressure systolic increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood glucose increased, Blood
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, METOPROLOL, MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Biliary increased, Mania, Neurotoxicity
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Acute coronary syndrome, Atrial fibrillation, Cerebral infarction, Deep vein thrombosis, Ecchymosis, Graft versus host disease in skin, Pseudoaneurysm
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOXORUBICIN, FLUOROURACIL, VINCRISTINE reactions: Neuropathy peripheral, Neutropenia, Pyrexia, Sensory neuropathy
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISOLONE reactions: Epstein-Barr virus positive mucocutaneous ulcer, Lymphoproliferative disorder
+serious: 1 patientsex: 2 drugs: AZACITIDINE reactions: Hypersensitivity, Hyperaemia, Injection site hyperaemia
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, MEROPENEM, VORICONAZOLE reactions: Acute respiratory failure, Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: APIXABAN, INSULIN NOS, POLYETHYLENE GLYCOL 3350 reactions: Septic shock
+serious: 1 patientsex: 1 drugs: DOLUTEGRAVIR, EMTRICITABINE, TENOFOVIR DISOPROXIL FUMARATE reactions: Immune reconstitution inflammatory syndrome
+serious: 1 patientsex: 2 drugs: ATORVASTATIN CALCIUM reactions: Myasthenia gravis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Intestinal perforation
+serious: 1 patientsex: 1 drugs: AMPICILLIN, AMPICILLIN SODIUMSULBACTAM SODIUM, ISAVUCONAZOLE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective, Mucormycosis
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, FENTANYL, OXYTOCIN reactions: Foetal distress syndrome, Uterine hypertonia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, PREDNISOLONE, VINCRISTINE reactions: Cellulitis, Pancytopenia, Pneumonia, Neuropathy peripheral, Pancytopenia, Vulvovaginitis
+serious: 1 patientsex: 1 drugs: ASPIRIN, DIAZEPAM, MORPHINE, NITROGLYCERIN, PROPOFOL, SCOPOLAMINE reactions: Drug ineffective, Hypotension, Left ventricular dysfunction
+serious: 1 patientsex: 2 drugs: DOXORUBICIN HYDROCHLORIDE reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: TIZANIDINE HYDROCHLORIDE reactions: Hypertriglyceridaemia, Pancreatitis acute
+serious: 2 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, LEVETIRACETAM, OXCARBAZEPINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Pathogen resistance
+serious: 1 patientsex: 1 drugs: CAPECITABINE, ELOXATIN, OXALIPLATIN reactions: Diahydropyrimidine dehydrogenase deficiency
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, NIVOLUMAB, TELMISARTAN reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: BETAMETHASONE, PROGESTERONE reactions: Abdominal pain, Premature labour, Premature rupture of membranes
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Acute kidney injury, Hypercalcaemia, Hyperplasia of the parathyroid gland
+serious: 1 patientsex: 1 drugs: VANCOMYCIN reactions: Retinal haemorrhage
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, IRINOTECAN, LEUCOVORIN, RAMUCIRUMAB reactions: Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: MIGLUSTAT reactions: Gastrointestinal disorder
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PACLITAXEL HYDROCHLORIDE, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, PEGFILGRASTIM, PACLITAXEL, POTASSIUM, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE, POTASSIUM
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, METFORMIN HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Acute respiratory distress syndrome, Biliary tract infection, Biliary stenosis, Bile leakage, Biliary tract infection bacterial, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, C-re
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN, RITUXIMAB, VINCRISTINE reactions: Adenovirus infection, Cystitis haemorrhagic, Hepatitis E, Liver injury
+serious: 1 patientsex: 2 drugs: AMITRIPTYLINE, BUPROPION, CITALOPRAM HYDROBROMIDE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, LISDEXAMFETAMINE, OLANZAPINE, ZOLPIDEM TARTRATE reactions: Drug intolerance, Drug resistance, Oedema, Treatment failure
+serious: 1 patientsex: 1 drugs: IBUPROFEN reactions: Duodenal ulcer, Haemophilus infection, Haemoglobin decreased, Haemorrhagic shock, Haemoglobin decreased, Haemoglobin decreased, Haemoglobin decreased, Haemophilus infection, Haemoglobin decreased, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Haemophilus infection, Hae
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CARBIMAZOLE, PROPRANOLOL HYDROCHLORIDE reactions: Drug interaction, Hypotension
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, HYDROXYCHLOROQUINE, TOCILIZUMAB reactions: Hypoxia, Respiratory disorder, Thrombosis
+serious: 1 patientsex: 1 drugs: OMBITASVIRPARITAPREVIRRITONAVIRDACLATASVIR, SOFOSBUVIR reactions: Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotrans
+serious: 1 patientsex: 1 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, FLUDARABINE PHOSPHATE, METHOTREXATE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPRED
+serious: 1 patientsex: 2 drugs: ASPIRIN, HEPARIN SODIUM, NITROGLYCERIN reactions: Cardiac arrest, Pericardial haemorrhage
+serious: 1 patientsex: 2 drugs: PACLITAXEL, TRASTUZUMAB reactions: Anaphylactoid reaction, Dyspnoea, Hypotension, Organising pneumonia
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE, METHYLPREDNISOLONE reactions: Iron deficiency anaemia, Sarcoidosis
+serious: 1 patientsex: 1 drugs: PASIREOTIDE reactions: Cushings disease, Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Leukopenia, Neutropenia
+serious: 1 patientsex: 2 drugs: ALBUTEROL, ACETAMINOPHENHYDROCODONE, DEXAMETHASONE, HYDROCODONEHYDROCODONE BITARTRATE, LISINOPRIL, ONDANSETRON, NEBIVOLOL, SIMVASTATIN, SULFAMETHOXAZOLETRIMETHOPRIM, TEMOZOLOMIDE reactions: Aplastic anaemia
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, METHYLPREDNISOLONE reactions: Reversible cerebral vasoconstriction syndrome
+serious: 1 patientsex: 1 drugs: PENICILLIN G BENZATHINE reactions: Jarisch-Herxheimer reaction
+serious: 1 patientsex: 1 drugs: PROPRANOLOL HYDROCHLORIDE reactions: Abdominal encapsulating peritoneal fibrosis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, INTERFERON GAMMA, INTERLEUKIN, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB reactions: Myocarditis
+serious: 1 patientsex: 1 drugs: BETAMETHASONE, ERYTHROMYCIN reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Drug ineffective, Haemorrhagic transformation stroke
+serious: 1 patientsex: 2 drugs: MIGLUSTAT reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: AZTREONAM, CYTARABINE, MEROPENEM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Aspartate aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Aspartate aminotransferase increased, Aspartate aminotransferase increased, Aspartate aminotransferase increased, Aspartate aminotransfer
+serious: 1 patientsex: 2 drugs: DICLOFENAC reactions: Drug interaction, Jaundice
+serious: 1 patientsex: 1 drugs: IMATINIB reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, CANDELOTAXEL, LIDOCAINE, PROPOFOL reactions: Atrial fibrillation, Sinus bradycardia, Tachycardia
+serious: 1 patientsex: 2 drugs: PEGINTERFERON ALFA-2B, RIBAVIRIN reactions: Optic ischaemic neuropathy
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, DEXAMETHASONE, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: FLUCONAZOLE, KETOCONAZOLE reactions: Anaphylactic reaction, Dehydration, Hypotension, Nausea, Tinnitus
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE reactions: Immune-mediated necrotising myopathy
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, ERLOTINIB, GEFITINIB, PACLITAXEL reactions: Neutropenia, Myelosuppression, Gastrointestinal disorder
+serious: 1 patientsex: 1 drugs: AMIODARONE, LIDOCAINE, ONDANSETRON reactions: Electrocardiogram QT prolonged, Torsade de pointes, Ventricular fibrillation
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOCETAXEL, TRASTUZUMAB reactions: Cardiac failure acute
+serious: 1 patientsex: 1 drugs: EFAVIRENZ, EMTRICITABINE, GANCICLOVIR, TENOFOVIR DISOPROXIL FUMARATE, VALGANCICLOVIR reactions: Cytomegalovirus infection, Immune reconstitution inflammatory syndrome, Intestinal perforation
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, CEFTRIAXONE, FENERTINIDE reactions: Drug interaction, Hepatic failure, Pyrexia
+serious: 1 patientsex: 1 drugs: CALCITRIOL, CALCIUM CARBONATE, CALCIUM GLUCONATE, ERGOCALCIFEROL, HYDROCHLOROTHIAZIDE, CALCIUM CARBONATE, ZOLEDRONIC ACID reactions: Drug ineffective, Hypocalcaemia, Renal failure, Treatment failure
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Device occlusion, Upper gastrointestinal haemorrhage
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Bone marrow failure
+serious: 1 patientsex: 2 drugs: METRONIDAZOLE reactions: Toxic encephalopathy
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, BASILIXIMAB, GLIPIZIDE, PIOGLITAZONE, PREDNISOLONE, TACROLIMUS reactions: Abscess limb, Diabetes mellitus, Scedosporium infection
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CYCLOSPORINE, MEROPENEM, MYCOPHENOLATE MOFETIL reactions: Burkholderia pseudomallei infection, Malignant neoplasm progression
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE, LEVETIRACETAM reactions: Cholecystitis, Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: TACROLIMUS reactions: Proteinuria
+serious: 1 patientsex: 1 drugs: ETOPOSIDE reactions: Acute hepatic failure, Hepatic encephalopathy, Multiple organ dysfunction syndrome
+serious: 1 patientsex: 1 drugs: CERTOLIZUMAB PEGOL reactions: Thrombotic microangiopathy
+serious: 1 patientsex: 2 drugs: CLONAZEPAM, ZOLPIDEM TARTRATE reactions: Bundle branch block right, Drug dependence, Drug withdrawal syndrome, Irritability, Irritability, Psychomotor hyperactivity, Tremor
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, FAMOTIDINE, TIZANIDINE reactions: Cystitis haemorrhagic
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, OLAPARIB reactions: Cognitive disorder, Hyponatraemia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: METHADONE HYDROCHLORIDE reactions: Accidental exposure to product by child, Hypotension, Intentional overdose, Miosis, Respiratory depression, Suicide attempt, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ANASTROZOLE, CYCLOPHOSPHAMIDE, DOXORUBICIN, PACLITAXEL, TRASTUZUMAB reactions: Nausea
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE, OXCARBAZEPINE reactions: Cognitive disorder, Drug interaction, Epilepsy, Nausea, Off label use, Product use in unapproved indication, Seizure, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DOCETAXEL reactions: Deep vein thrombosis, Oesophageal necrosis, Oesophageal candidiasis, Oesophageal fistula
+serious: 1 patientsex: 2 drugs: ALENDAZOLE reactions: Dipylidiasis
+serious: 1 patientsex: 2 drugs: DOCUSATE SODIUM, FUROSEMIDE, ROSUVASTATIN reactions: Acute kidney injury, Metabolic acidosis, Renal tubular acidosis
+serious: 2 patientsex: 2 drugs: IVABRADINE reactions: Off label use
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, FOLIC ACID, VALPROIC ACID reactions: Baller-Gerold syndrome, Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: AZULFIDINE, AZATHIOPRINE, HYDROMORPHONE, INFLIXIMAB, SOLUMERIDE reactions: Bacteraemia, Abdominal distension, Ascites, Clostridium difficile infection, Gastrointestinal perforation, Nausea, Pseudomembranous colitis, Small intestinal obstruction, Tachycardia
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, INFLIXIMAB, METHOTREXATE, PREDNISONE, RITUXIMAB reactions: Chorioretinopathy, Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: PREDNISOLONE reactions: Cerebral sinus thrombosis, Haematuria
+serious: 1 patientsex: 2 drugs: TAPENTADOL HYDROCHLORIDE reactions: Exposure during pregnancy, Serotonin syndrome
+serious: 1 patientsex: 1 drugs: DICLOFENAC reactions: Stevens-Johnson syndrome
+serious: 1 patientsex: 2 drugs: ASCORBIC ACID, CLONAZEPAM, FERROUS FUMARATE, OLANZAPINE reactions: Restless legs syndrome
+serious: 1 patientsex: 2 drugs: ASPIRIN, CARVEDILOL, ENALAPRIL, FOLIC ACID, FUROSEMIDE, METHOTREXATE, SIMVASTATIN reactions: Febrile neutropenia, Mucocutaneous haemorrhage, Pancytopenia, Peripheral swelling
+serious: 1 patientsex: 2 drugs: ASPIRIN, CLARITHROMYCIN, LYSOZYME HYDROCHLORIDE reactions: Drug eruption, Drug hypersensitivity
+serious: 1 patientsex: 2 drugs: CHLORPROMAZINE, HALOPERIDOL, OLANZAPINE, RISPERIDONE, TRAZODONE HYDROCHLORIDE reactions: Dysphagia, Fatigue, Social disorder, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, CEFTRIAXONE, PROBENECID reactions: Jarisch-Herxheimer reaction, Hyperemesis gravidarum
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, CYCLOSPORINE, HEPARIN SODIUM, MYCOPHENOLIC ACID, OMEPRAZOLE, PREDNISONE, RANITIDINE, WARFARIN reactions: Drug intolerance, Drug intolerance, Drug intolerance, Gastrointestinal disorder, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM reactions: Acute kidney injury, Nephropathy toxic
+serious: 1 patientsex: 2 drugs: GUAIFENESIN, PHYTONADIONE HYDROCHLORIDE, THYROXINE reactions: Angle closure crisis
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, DEXAMETHASONE, TEMOZOLOMIDE reactions: Drug ineffective, Gadolinium adenoma, Neurological decompensation, Treatment failure
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Kaposis sarcoma
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, CHLORPHENIRAMINE, LIDOCAINE reactions: Anaphylactic reaction
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, PACLITAXEL reactions: Bone disorder, Gingival bleeding, Gingival swelling, Oral disorder, Periodontitis
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DEXAMETHASONE reactions: Diarrhoea
+serious: 1 patientsex: 2 drugs: HYDROXYUREA, NILOTINIB reactions: Neutropenia, Off label use, QT prolonged
+serious: 1 patientsex: 1 drugs: DICETAMINE reactions: Gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DAUNORUBICIN, IFOSFAMIDE, METHOTREXATE, VINDESINE reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 2 drugs: ZONISAMIDE, VALPROIC ACID reactions: Myoclonic epilepsy with ragged red fibres
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, CARVEDILOL, CLOPIDOGREL BISULFATE, DIGOXIN, ISOSORBIDE MONONITRATE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, TORSEMIDE, VIVBRADINE reactions: Bradycardia, Drug interaction, Hypotension, Metabolic alkalosis, Orthostatic hypotension, Pyrexia, Respiratory alkalosis, Respiratory alkalosis, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: CISPLATIN, ASPIRIN reactions: Colitis
+serious: 1 patientsex: 1 drugs: ASPIRIN, DASATINIB, IMATINIB MESYLATE, METHYLPREDNISOLONE, PREDNISONE, VINCRISTINE reactions: Diabetes mellitus, Drug intolerance, Pancreatitis, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: FLUCONAZOLE reactions: Alopecia, Chloroma, Drug ineffective, Erosis, Xerosis, Skin enlargement
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN reactions: Clostridium difficile infection, Klebsiella infection, Septic shock
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Neutropenia
+serious: 1 patientsex: 2 drugs: IMATINIB MESYLATE reactions: Fatigue, Off label use
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Colitis, Deep vein thrombosis, Hemiplegia, Pneumonitis, Renal infarction, Splenic infarction, Vasculitis
+serious: 1 patientsex: 1 drugs: PAZOPANIB reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM reactions: Condition aggravated, Dystonia, Muscle spasms, Muscle rigidity, Muscle twitching, Muscle twitching, Muscle twitching, Muscle spasms, Muscle twitching, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms, Muscle spasms
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, DEGARELIX, GOSERELIN, LEUPROLIDE ACETATE reactions: Drug ineffective, Leydig cell carcinoma
+serious: 1 patientsex: 1 drugs: ASPIRIN, BISOPROLOL, CALCIUM CARBONATE, CHOLECALCIFEROL, CYCLOPHOSPHAMIDE, HYDROCORTISONE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLP
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE reactions: Aspergillus infection, Bone perforation, Gait disturbance, Mouth ulceration, Mouth haemorrhage, Mouth hole, Mouth swelling, Mouth ulceration, Mouth perforation, Mouth oedema, Mouth ulceration, Mouth swelling, Mouth ulceration, Mouth perforation, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth ulceration, Mouth
+serious: 1 patientsex: 2 drugs: MEROPENEM, NITROFURANTOIN, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Clostridium difficile infection, Leukocytosis
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Acute myeloid leukaemia
+serious: 1 patientsex: 1 drugs: CLINDAMYCIN, IMIPENEM, MEROPENEM, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug intolerance
+serious: 1 patientsex: 1 drugs: HYDROCORTISONE, LEVOTHYROXINE, PREDNISONE reactions: Adrenocorticotropic hormone increased, Cushings disease
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, NITISINONE reactions: Hepatocellular carcinoma
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, PROPARACAINE HYDROCHLORIDE reactions: Endophthalmitis, Off label use, Product use issue
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, CELECOXIB, DEXAMETHASONE, FENTANYL, GABAPENTIN, HYDROMORPHONE, METHADONE HYDROCHLORIDE reactions: Drug interaction, Hallucination, Meningitis meningoencephalitis, Urinary tract infection bacterial
+serious: 1 patientsex: 2 drugs: DIAZEPAM, FLUOXETINE HYDROCHLORIDE, METHOTREXATE, MIANSERIN, SERTRALINE HYDROCHLORIDE reactions: Drug interaction, Drug level decreased, Drug level increased, Drug resistance, Hypotension, Orthostatic hypotension, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation, Psychomotor retardation,
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, DIMETHYL FUMARATE, MORPHINE, SODIUM CHLORIDE reactions: Disease recurrence
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, INFLIXIMAB reactions: Intestinal tuberculosis
+serious: 1 patientsex: 2 drugs: HYDROMORPHONE, MORPHINE SULFATE reactions: Toxic encephalopathy
+serious: 1 patientsex: 2 drugs: CLONIDINE, AROTINOLOL, CLONIDINE HYDROCHLORIDE, CLONIDINE HYDROCHLORIDE, ERYTHROPOIETIN, LACIDIPINE, OLMESARTAN, NITRIPIPINE, TELMISARTAN, TERAZOSIN reactions: Adrenal gland hyperplasia
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, VANCOMYCIN reactions: Acute kidney injury, Drug-induced liver injury, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: TESTOSTERONE reactions: Dissociative identity disorder, Hostility, Homicidal ideation, Suicidal ideation
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, OLANZAPINE, QUETIAPINE reactions: Drug ineffective, Overeating
+serious: 1 patientsex: 1 drugs: ERLOTINIB, GABAPENTIN, OMEPRAZOLE reactions: Adrenal insufficiency, Malignant neoplasm progression, Metastases to pituitary
+serious: 1 patientsex: 2 drugs: IPILIMUMAB, NIVOLUMAB reactions: Autoimmune hepatitis, Vitiligo
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Condition aggravated, Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DEXAMETHASONE, ETOPOSIDE, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB reactions: Drug ineffective, Leukoencephalopathy
+serious: 1 patientsex: 2 drugs: DIMETHYL FUMARATE reactions: Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, PACLITAXEL reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: FUROSEMIDE reactions: Pancreatitis necrotising
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, POSACONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: GEMCITABINE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ASPIRIN, CIPROFLOXACIN, NATAMYCIN, METOPROLOL, SIMVASTATIN, VANCOMYCIN, VORICONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Oesophagitis
+serious: 1 patientsex: 1 drugs: ASPIRINCLOPIDOGREL BISULFATE, CEFTRIAXONE SODIUMSULBACTAM SODIUM, ENOXAPARIN, ERYTHROMYCIN, FENTANYL, ENOXAPARIN SODIUM, ERYTHROMYCINMIDAZOLAM HYDROCHLORIDE, ENOXAPARIN SODIUM, ENOXAPARIN SODIUM, FENTANYL, ENOXAPARIN SODIUM, ENOXAPARIN SODIUM, ENOXAPARIN SODIUM, ERYTHROMYCIN, METRONIDAZOLE, PANTOPRAZOLE, POTASSIUM CHLORIDE, SEVOFLURANE, SEVOFLURANE, VECURONIUM BROMIDE reactions: Drug interaction, Drug level increased, Drug interaction, Haemodynamic instability, Hypoxia, Ileus paralytic, Respiratory distress, Respiratory distress, Tachy
+serious: 1 patientsex: 1 drugs: ABOBOTULINUM TOXIN TYPE A reactions: Myasthenia gravis, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: CILASTATIN SODIUMIMIPENEM, VENLAFAXINE HYDROCHLORIDE reactions: Cardiac failure, Cardiomyopathy, Interstitial lung disease
+serious: 1 patientsex: 1 drugs: INSULIN ASPART, INSULIN DETEMIR reactions: Hypoglycaemic coma
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Alopecia, Asthenia, Bone pain, Dyspnoea, Fatigue, Hepatic enzyme increased, Hepatic function abnormal, Metastases to lung, Nausea, Neutropenia, Off label use, Thrombocytopenia, Vomiting
+serious: 1 patientsex: 2 drugs: PREDNISONE reactions: Growth hormone decreased
+serious: 1 patientsex: 2 drugs: DISULFIRAM reactions: Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: NAPROXEN, SULFASALAZINE reactions: Bone marrow failure, Pancytopenia
+serious: 1 patientsex: 2 drugs: AXITINIB, ESTAZOLAM, ETIZOLAM, LANSOPRAZOLE, NIFEDIPINE, SUNITINIB MALATE reactions: Bradycardia, Hyperkalaemia, Metabolic acidosis, Renal impairment, Sinus arrest
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, OXCARBAZEPINE, PAROXETINE, VALPROIC ACID reactions: Drug eruption, Rash pruritic
+serious: 1 patientsex: 2 drugs: BUPROPION, ESCITALOPRAM OXALATE, HYAOCYAMINE SULFATE, OMEPRAZOLE, TESTOSTERONE CYPIONATE reactions: Cystic pancreatic neoplasm
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, INTERFERON reactions: Raynaud syndrome
+serious: 1 patientsex: 1 drugs: ASPIRIN, HEPARIN SODIUM reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALPRAZOLAM, HYDROCHLOROTHIAZIDE, MELOXICAM, OMEPRAZOLE, SIMVASTATIN reactions: Acute generalised exanthematous pustulosis
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, ASPIRIN, BUDESONIDE, CYCLOPHOSPHAMIDE, CYTARABINE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE
+serious: 1 patientsex: 1 drugs: MERCAPTOPURINE, METHOTREXATE, VINCRISTINE reactions: Pneumonitis
+serious: 1 patientsex: 1 drugs: PIPERACILLIN SODIUMTAZOBACTAM SODIUM reactions: Drug interaction, Electrocardiogram QT prolonged, Hepatic function abnormal
+serious: 1 patientsex: 1 drugs: HALOPERIDOL, OLANZAPINE, SERTRALINE HYDROCHLORIDE, RISPERIDONE reactions: Hypotension, Paranoia
+serious: 1 patientsex: 2 drugs: MIDAZOLAM HYDROCHLORIDE reactions: Hepatitis toxic
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE HYDROCHLORIDE, FOSCARNET, GANCICLOVIR, RITUXIMAB, VALGANCICLOVIR reactions: Cytomegalovirus infection, Encephalopathy, Gastritis, Neutropenia, Ocular oedema, Retinitis, Staphylococcal enterotoxin B infection, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: HYDROXYCHLOROQUINE, OSELTAMIVIR reactions: Accidental overdose, Electrocardiogram QT prolonged, Sinus bradycardia
+serious: 1 patientsex: 2 drugs: LEUPROLIDE ACETATE reactions: Pseudotumour cerebri
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEPHALEXIN, LEVOFLOXACIN, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, HEPARIN SODIUM, FERROUS SULFATE reactions: Acute lymphocytic leukaemia
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, EPLERENONE, OMBITASVIRPARITAPREVIRRITONAVIR, RIBAVIRIN reactions: Cough, Cough erythematous, Cough suppurative, Cough erythematous, Cough suppurative, Cough erythematous, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, Cough suppurative, C
+serious: 1 patientsex: 2 drugs: BOTULINUM TOXIN TYPE A reactions: Aortic pseudoaneurysm
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Hepatitis, Off label use, Pyrexia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: BEDAZILINE MESYLATE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, DOXORUBICIN, ETOPOSIDE, METHOTREXATE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Arrhythmia, Death, Drug interaction, Electrocardiogram QT prolonged
+serious: 1 patientsex: 2 drugs: DOXORUBICIN, IFOSFAMIDE, GRANULOCYTE COLONY-STIMULATING FACTOR NOS reactions: Ascites, Bone marrow failure, Febrile neutropenia, Neutropenia, Off label use, Product use in unapproved indication, Product use issue, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: AMIODARONE, ESMOLOL SUCCINATE reactions: Drug ineffective, Drug intolerance, Drug resistance, Shock
+serious: 1 patientsex: 2 drugs: SUNITINIB MALATE reactions: Cardiac toxicity, Drug resistance, Malignant neoplasm progression, Metastases to pelvis, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, ALFAMETILDOPA, ENAPAREN, FUROSEMIDE, HEPARIN SODIUM, SPIRONOLACTONE reactions: Drug ineffective, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, ADALIMUMAB, MYCOPHENOLIC ACID, PREDNISOLONE reactions: Drug dependence, Drug resistance, Hepatic enzyme increased, Polyarthritis
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENOXYCODONE HYDROCHLORIDE, DEXLANSOPRAZOLE, MESALAMINE, ONDANSETRON, OXYCODONE, SUMATRIPTAN, TOPIRAMATE reactions: Angle closure glaucoma, Iridotomy, Pupils absent, Pupils afferent, Pupils reversible, Pupils oedema, Pupils oedema peripheral, Pupils reversible, Pupils trabeculated, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, VANCOMYCIN reactions: Drug ineffective, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Teratoma
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOXORUBICIN, PACLITAXEL reactions: Diarrhoea, Hypertension, Polyneuropathy, Stress
+serious: 1 patientsex: 1 drugs: FLUOXETINE HYDROCHLORIDE, LAMOTRIGINE, KETOROLAC TROMETHAMINE reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: CLINDAMYCIN, HYDROXYCHLOROQUINE reactions: Actinomycosis, Meningoencephalitis, Septic shock
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CYCLOPHOSPHAMIDE, HUMAN IMMUNOGLOBULIN G, LEVETIRACETAM, METHYLPREDNISOLONE, OLANZAPINE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, QUETIAPINE, VALPROIC ACID reactions: Drug ineffective, Hypotension
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Diarrhoea, Nonalcoholic steatohepatitis, Steatohepatitis
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CEFEPIME HYDROCHLORIDE, PREDNISONE reactions: Toxic encephalopathy
+serious: 2 patientsex: 2 drugs: AMLODIPINE BESYLATE, ATORVASTATIN, LISINOPRIL, METFORMIN HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CLOPIDOGREL BISULFATE, ROSUVASTATIN, VALSARTAN reactions: Optic atrophy, Treatment failure
+serious: 1 patientsex: 1 drugs: MERCAPTOPURINE, METHOTREXATE reactions: Immune thrombocytopenic purpura
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, LACOSAMIDE, LEVETIRACETAM, METHOTREXATE, MANNITOL, ONDANSETRON, METOCLOPRAMIDE, ONDANSETRON HYDROCHLORIDE, METHOTREXATE SODIUM, ONDANSETRON HYDROCHLORIDE, VALPROIC ACID reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, PREDNISOLONE, TACROLIMUS, VALACYCLOVIR HYDROCHLORIDE, VORICONAZOLE reactions: Chronic kidney disease, Drug ineffective, Mycobacterium abscessus infection, Peritonitis
+serious: 1 patientsex: 2 drugs: RITUXIMAB reactions: Anaemia, Drug ineffective, Gastrointestinal haemorrhage, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: CABERGOLINE, MIRTAZAPINE, QUETIAPINE reactions: Drug resistance, Drug level increased, Drug level increased, Ischaemic stroke, Psychotic disorder
+serious: 1 patientsex: 1 drugs: CRIZOTINIB reactions: Diffuse alveolar damage, Organising pneumonia
+serious: 1 patientsex: 2 drugs: POMALIDOMIDE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Disseminated Varicella zoster virus infection
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PEMETREXED reactions: Oesophagitis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: DAUNORUBICIN, TRETINOIN reactions: Myocarditis
+serious: 1 patientsex: 2 drugs: ATENOLOL, LORAZEPAM, MIRTAZAPINE, METFORMIN HYDROCHLORIDE reactions: Intentional overdose, Lactic acidosis
+serious: 1 patientsex: 1 drugs: FILGRASTIM reactions: Acute myeloid leukaemia, Neutropenia
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, INFLIXIMAB, METHOTREXATE, PREDNISONE, RITUXIMAB reactions: Rheumatoid nodule
+serious: 1 patientsex: 1 drugs: CLOZAPINE, LITHIUM, SERTRALINE HYDROCHLORIDE, VALPROIC ACID reactions: Drug ineffective, Hypochondriasis
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, CLOPIDOGREL BISULFATE, FONDAPARINUX, GLYCERIN, WARFARIN reactions: Rash petechial
+serious: 1 patientsex: 1 drugs: IBRUTINIB, PREDNISONE reactions: Central nervous system aspergillosis
+serious: 1 patientsex: 2 drugs: AZACITIDINE, HYDROXYUREA, IMATINIB, INTERFERON BETA-1A reactions: Myelodysplastic syndrome, Treatment failure
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM, PROPOFOL reactions: Ischaemic priapism
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CARVEDILOL, DIGOXIN, FUROSEMIDE, RAMIPRIL, SPIRONOLACTONE, VALSARTAN reactions: Drug ineffective, Mediastinal fluid collection, Off label use
+serious: 2 patientsex: 2 drugs: HYDROXYZINE HYDROCHLORIDE, METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: FIBRITALOL, LIPIDIL ONE, OMEPRAZOLE reactions: Off label use
+serious: 1 patientsex: 2 drugs: CEPHALEXIN reactions: Hypernatraemia, Hypokalaemia, Paralysis, Renal tubular acidosis, Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, SORAFENIB reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, VINCRISTINE reactions: Candida infection, Neutropenia, Sepsis
+serious: 1 patientsex: 2 drugs: CARBIDOPALEVODOPA, PRAMIPEXOLE reactions: Complex regional pain syndrome, Dystonia
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Thrombocytopenia
+serious: 1 patientsex: 1 drugs: AXITINIB, PEMBROLIZUMAB, SUNITINIB MALATE reactions: Blindness, Retinal detachment, Uveitis
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Skin toxicity
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Aggression, Agitation, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Aggression, Ag
+serious: 1 patientsex: 1 drugs: ASPIRIN, CYPROHEPTADINE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPRED
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Hepatitis B reactivation
+serious: 1 patientsex: 2 drugs: TRIAMCINOLONE reactions: Conjunctival haemorrhage, Embolism, Retinal artery occlusion, Retinal vascular disorder, Visual acuity reduced
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE reactions: Lymphopenia
+serious: 1 patientsex: 2 drugs: ALLOPURINOL, AMIODARONE, AMIODARONE HYDROCHLORIDE, DABIGATRAN ETEXILATE MESYLATE, DILTIAZEM, LEVOTHYROXINE, PANTOPRAZOLE SODIUM, RAMIPRIL, ROSUVASTATIN reactions: Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOXORUBICIN, PACLITAXEL reactions: Acute kidney injury, Fatigue, Nausea
+serious: 1 patientsex: 2 drugs: CISPLATIN, DEXAMETHASONE, GEMCITABINEGEMCITABINE HYDROCHLORIDE, RITUXIMAB reactions: Coronary artery vasoconstriction
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, NIVOLUMAB reactions: Autoimmune encephalopathy, Cerebellar toxicity
+serious: 1 patientsex: 1 drugs: CAPECITABINE, DALTEPARIN SODIUM, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, SOTALOL, VALSARTAN reactions: Atrial fibrillation, Dizziness, Flushing, Sinus arrest, Syncope
+serious: 1 patientsex: 2 drugs: SIROLIMUS reactions: Pseudoneutropenia
+serious: 1 patientsex: 1 drugs: ATOVAQUONE, PYRIMETHAMINE, SULFADIAZINE reactions: Acute kidney injury, Drug intolerance, Hepatic enzyme increased, Urolithiasis
+serious: 1 patientsex: 2 drugs: SULFASALAZINE reactions: Neutropenic colitis
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ISOSORBIDE MONONITRATE, LEVOTHYROXINE, METFORMIN HYDROCHLORIDE, OMEPRAZOLE, RANOLAZINE HYDROCHLORIDE reactions: Acute kidney injury, Bradycardia, Hyperkalaemia, Renal failure
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PEMETREXED reactions: Haematotoxicity
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE HYDROCHLORIDERITUXIMAB reactions: COVID-19
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CLORAZEPATE, DULOXETINE, PREGABALIN, TRAMADOL reactions: Hypertensive crisis, Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 2 drugs: PANTOPRAZOLE SODIUM reactions: Haemolytic anaemia
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, CISPLATIN, DEXAMETHASONE, DIMENHYDRINATE, MAGNESIUM SULFATE, METOCLOPRAMIDE, MANNITOL, OMEPRAZOLE, POTASSIUM CHLORIDE, SODIUM CHLORIDE reactions: Hypersensitivity vasculitis
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, CAFFEINE, BUTALBITAL reactions: Alcohol, Intentional overdose, Lactic acidosis, Mental status changes, Nausea, Overdose, Mental status changes, Vomiting
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL reactions: Lymph node enlargement
+serious: 1 patientsex: 1 drugs: GABAPENTIN, IBUPROFEN, SOLIFENACIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: LINEZOLID, POSACONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: DONEPEZIL, PREGABALIN, QUETIAPINE, ROCURONIUM BROMIDE reactions: Drug interaction, Neuromuscular block prolonged
+serious: 1 patientsex: 1 drugs: AMANTADINE HYDROCHLORIDE, ARIPIPRAZOLE, BENZTROPINE, LORAZEPAM, OLANZAPINE reactions: Confusional state, Pneumonia aspiration
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE, POMALIDOMIDE reactions: Aphasia, Coma, Neurotoxicity, Sedation
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, BUDESONIDE reactions: Drug ineffective, Papilloma viral infection
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, EPIRUBICIN, FLUOROURACIL reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: AMISULPRIDE, CLOZAPINE, LANSOPRAZOLE, OMEPRAZOLE reactions: Drug interaction, Drug-induced liver injury, Inflammation, Myocarditis, Off label use, Pyrexia, Tachycardia
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Locked-in syndrome
+serious: 1 patientsex: 1 drugs: DACTINOMYCIN, METHYLPREDNISOLONE, PREDNISOLONE reactions: Hepatitis C
+serious: 1 patientsex: 2 drugs: RIVASTIGMINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: SIROLIMUS reactions: Alkaline phosphatase increased, Gastroenteritis, Pyrexia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ASPIRIN, HYDRALAZINE HYDROCHLORIDE, METOPROLOL, LISINOPRIL, SIMVASTATIN reactions: Acute kidney injury, Anti-neutrophil cytoplasmic antibody positive vasculitis, Glomerulonephritis rapidly progressive, Pulmonary haemorrhage
+serious: 1 patientsex: 1 drugs: DEHYDROEPINE PIPERACILLIN, HYDROCORTISONE, TESTOSTERONE reactions: Cytomegalovirus chorioretinitis, Drug abuse
+serious: 2 patientsex: 2 drugs: DIPPHENHYDRAMINE, DIPHENHYDRAMINE, MECLIZINE, METOCLOPRAMIDE, ONDANSETRON, PROCHLORPERAZINE reactions: Drug ineffective, Maternal exposure during pregnancy
+serious: 1 patientsex: 2 drugs: AMOXICILLIN reactions: Endocarditis, Pneumonia streptococcal
+serious: 1 patientsex: 1 drugs: CLOZAPINE, OLANZAPINE, RISPERIDONE, VALPROIC ACID, VENLAFAXINE HYDROCHLORIDE reactions: Delirium, Drug ineffective, Neuroleptic malignant syndrome
+serious: 1 patientsex: 1 drugs: PACLITAXEL, RAMUCIRUMAB reactions: Vascular pseudoaneurysm
+serious: 1 patientsex: 2 drugs: LEVETIRACETAM, VALPROIC ACID reactions: Bradycardia, Seizure, Syncope
+serious: 1 patientsex: 2 drugs: LACOSAMIDE, LEVETIRACETAM, LORAZEPAM, MIDAZOLAM HYDROCHLORIDE, PENTOBARBITAL, PHENOBARBITAL, PHENYTOIN, TOPIRAMATE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, ENOXAPARIN SODIUM, GLICLAZIDE, IBUPROFEN, METFORMIN HYDROCHLORIDE, PREDNISONE reactions: Diverticular perforation
+serious: 1 patientsex: 1 drugs: BISOPROLOL, INSULIN NOS, MESALAMINE, RIVAROXABAN reactions: Meningoencephalitis listeria
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, ASPIRIN, IPRATROPIUM BROMIDEALBUTEROL SULFATE, PREDNISONE reactions: Colitis ischaemic, Lower gastrointestinal haemorrhage, Neuropathy peripheral, Off label use, Rash vasculitis
+serious: 1 patientsex: 1 drugs: AZD9291, GEFITINIB, ZOLEDRONIC ACID reactions: Drug effective for unapproved indication, Off label use
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, INFLIXIMAB, METHOTREXATE, USTEKINUMAB reactions: Drug ineffective, Drug level below therapeutic, Drug level increased, Drug resistance, Drug level below therapeutic, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: PREGABALIN reactions: Anxiety, Depression, Drug withdrawal syndrome, Fear, Insomnia, Palpitations, Tremor
+serious: 1 patientsex: 2 drugs: FENTANYL, ISOFLURANE, THIOPENTAL, ROCURONIUM BROMIDE reactions: Exposure during pregnancy, Pulmonary embolism
+serious: 1 patientsex: 2 drugs: CYCLOSERINE, ETHIONAMIDE, LEVOFLOXACIN, KETAMYCIN, OLANZAPINE, PYRIDOXINE, TRIHEXYPHENIDYL reactions: Akathisia, Dysphagia, Extrapyramidal disorder, Neuroleptic malignant syndrome, Parkinsonism, Tremor
+serious: 1 patientsex: 2 drugs: AMITRIPTILINE, ESCITALOPRAM OXALATE, CLONAZEPAM, DESVENLAFAXINE, ETIZOLAM, OLANZAPINE, PAROXETINE, RISPERIDONE, SERTRALINE HYDROCHLORIDE reactions: Drug ineffective, Nausea, Treatment failure
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN, ETOPOSIDE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: DIPHENHYDRAMINE, EPINEPHRINE, METHYLPREDNISOLONE reactions: Myocardial infarction
+serious: 1 patientsex: 2 drugs: ADALIMUMAB reactions: Lupus-like syndrome
+serious: 1 patientsex: 1 drugs: ASPARAGINASE, GEMCITABINEGEMCITABINE HYDROCHLORIDE, OXALIPLATIN reactions: Mycobacterium fortuitum infection, Pneumonia, Septic shock
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, PACLITAXEL reactions: Anaemia, Constipation, Diarrhoea, Hypertension, Nausea, Neuropathy peripheral, Vomiting
+serious: 1 patientsex: 2 drugs: ACYCLOVIR, ASPIRIN, ATORVASTATIN, CALCIUM CARBONATE, CHOLECALCIFEROL, DEXAMETHASONE, LENALIDOMIDE, PANTOPRAZOLE, VENLAFAXINE HYDROCHLORIDE reactions: Cardiac failure, Dyspnoea, Palpitations
+serious: 1 patientsex: 2 drugs: TRASTUZUMAB reactions: Disease progression
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, MYCOPHENOLIC ACID, TACROLIMUS reactions: Anaemia normochromic, Duodenopathy, Weight decreased
+serious: 1 patientsex: 2 drugs: FAMOTIDINE reactions: Bulbar palsy
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CEFTRIAXONE, DEXAMETHASONE, METRONIDAZOLE, VANCOMYCIN reactions: Bradycardia, Cerebral mucormycosis, Condition aggravated, Mental status changes
+serious: 1 patientsex: 1 drugs: SPIRONOLACTONE reactions: Burkitts lymphoma
+serious: 1 patientsex: 2 drugs: CLOZAPINE, HALOPERIDOL reactions: Treatment failure
+serious: 1 patientsex: 1 drugs: BEZLOTOXUMAB, FIDAXOMICIN, VANCOMYCIN reactions: Clostridium difficile infection
+serious: 1 patientsex: 1 drugs: DENOSUMAB reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 1 drugs: FUROSEMIDE, LOSARTAN, OXYCODONE reactions: Atypical pneumonia, Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, DOXORUBICIN, FLUDARABINE PHOSPHATE, THIOTEPA, VINCRISTINE reactions: Graft versus host disease, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: HEPARIN SODIUM, WARFARIN reactions: Subcutaneous haemorrhage
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: BK virus infection, Collecting duct carcinoma
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYCLOSPORINE, FLUDARABINE PHOSPHATE, MEROPENEM, THYMOCYTE IMMUNE GLOBULIN, VANCOMYCIN reactions: Hypertension, Pseudomonas infection, Skin oedema
+serious: 1 patientsex: 1 drugs: AMIKACIN, AZITHROMYCIN ANHYDROUS, MEROPENEM, LINEZOLID, TIGECYCLINE reactions: Clostridium difficile colitis, Nausea
+serious: 1 patientsex: 1 drugs: HYDROCORTISONE, FLUDROCORTISONE, TOCILIZUMAB reactions: Adrenal insufficiency, Drug ineffective, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, PREDNISOLONE, TACROLIMUS reactions: Aplasia pure red cell, Myasthenia gravis, Thymoma
+serious: 1 patientsex: 1 drugs: ESCITALOPRAM OXALATE, GLICLAZIDE, IRBESARTANHYDROCHLOROTHIAZIDE, LORAZEPAM, METFORMIN HYDROCHLORIDE, NIFEDIPINE, OMEPRAZOLE, SIMVASTATIN, RILUZOLE reactions: Inappropriate antidiuretic hormone secretion
+serious: 1 patientsex: 1 drugs: CARVEDILOL, DAPTOMYCIN, FUROSEMIDE, ERTAPENEM SODIUM, LISINOPRIL, SPIRONOLACTONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: NITROFURANTOIN reactions: Respiratory arrest
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, IRINOTECAN, LEUCOVORIN, OXALIPLATIN, PYRAZINAMIDE, VINCRISTINE reactions: Disease progression
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, EPINEPHRINE, HYALURONIDASE, LIDOCAINE reactions: Brown syndrome
+serious: 1 patientsex: 2 drugs: CLOPIDOGREL BISULFATE reactions: Dermatitis bullous, Endothelial function test abnormal, Skin ulcer
+serious: 1 patientsex: 1 drugs: INFLIXIMAB, METHOTREXATE reactions: Diffuse large B-cell lymphoma, Non-Hodgkins lymphoma
+serious: 1 patientsex: 1 drugs: AZACITIDINE, BUSULFAN, CLOFARABINE, DAUNORUBICIN, ETOPOSIDE, MERCAPTOPURINE, PREDNISONE, RITUXIMAB, THIOGUAINE reactions: Acute myeloid leukaemia, Bone marrow failure, Drug ineffective, EBV viraemia, Splenomegaly
+serious: 1 patientsex: 1 drugs: LAMOTRIGINE, LEVETIRACETAM, OXCARBAZEPINE, TOPIRAMATE, VALPROIC ACID reactions: Cognitive disorder, Drug ineffective, Tic
+serious: 1 patientsex: 2 drugs: CEFEPIME HYDROCHLORIDE reactions: Acute kidney injury, Seizure
+serious: 1 patientsex: 1 drugs: PAZOPANIB reactions: Cardiac tamponade, Hypothyroidism
+serious: 1 patientsex: 1 drugs: INFLIXIMAB, METHOTREXATE, PREDNISOLONE, TACROLIMUS reactions: Mycobacterium marinum infection
+serious: 1 patientsex: 2 drugs: DICLOFENAC, CELECOXIB reactions: Gastric perforation
+serious: 1 patientsex: 2 drugs: ACYCLOVIR reactions: Cerebral haemorrhage
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: Herpes simplex oesophagitis
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, PAZOPANIB, SUNITINIB MALATE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: EPIRUBICIN, IFOSFAMIDE reactions: Toxic encephalopathy
+serious: 1 patientsex: 1 drugs: DOXORUBICIN HYDROCHLORIDE reactions: Hepatic encephalopathy
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOCETAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Off label use
+serious: 1 patientsex: 2 drugs: CYTARABINE, ETOPOSIDE, PACLITAXEL, TEMOZOLOMIDE reactions: Status epilepticus
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE, PREDNISONE, VINCRISTINE reactions: Clostridium difficile infection, Hydrothorax, Pneumonia
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ASPIRIN, FONDAPARINUX, HEPARIN SODIUM, OMEPRAZOLE, RAMIPRIL, SIMVASTATIN reactions: Deep vein thrombosis
+serious: 1 patientsex: 1 drugs: ASPIRIN, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: RANITIDINE reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 2 drugs: ASPIRIN reactions: Arterial embolism
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, METHAMPHETAMINE, PREGABALIN reactions: Coagulopathy, Drug abuse, Hepatic failure, Multiple organ dysfunction syndrome, Rhabdomyolysis, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: ALEMTUZUMAB, EVEROLIMUS, PREDNISOLONE, TACROLIMUS reactions: Cytomegalovirus infection, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, CIPROFLOXACIN, CEFTRIAXONE, GENTAMICIN, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ABIRATERONE, DOCETAXEL, ETOPOSIDE, FLUOROURACIL, IPILIMUMAB, NIVOLUMAB, TOPOTECAN HYDROCHLORIDE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: ATRORENT, BECLOMETHASONE, METHYLPREDNISOLONE, PANTOPRAZOLE SODIUM reactions: Aspergillus infection, Cardiac arrest, Drug ineffective, Strongyloidiasis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, ETOPOSIDE reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, IBUPROFEN reactions: Acute generalised exanthematous pustulosis
+serious: 1 patientsex: 2 drugs: ANASTRAZOLE, TOBRAMYCIN reactions: Myasthenia gravis
+serious: 1 patientsex: 1 drugs: CHOLECALCIFEROL, LEVOTHYROXINE, OXYGEN, PREDNISOLONE ACETATE, SODIUM CHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: MYCOPHENOLIC ACID, TACROLIMUS reactions: Histoplasmosis, Hepatitis granulomatous
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, PREDNISOLONE, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: DACLIZUMAB, FINGOLIMOD HYDROCHLORIDE reactions: Neuromyelitis optica spectrum disorder
+serious: 1 patientsex: 2 drugs: METRONIDAZOLE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: LEVOFLOXACIN reactions: Anaphylactic reaction, Hypotension, Tachycardia
+serious: 1 patientsex: 1 drugs: CISPLATIN, VINORELBINEVINORELBINE TARTRATE reactions: Malignant neoplasm progression, Metastases to lung, Metastases to bone, Metastases to lymph nodes, Metastases to gastrointestinal tract, Metastases to skin, Metastases to gastrointestinal tract, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to
+serious: 1 patientsex: 1 drugs: ASPIRIN, TICAGRELOR reactions: Von Willebrands disease acquired, Thrombocytosis
+serious: 1 patientsex: 1 drugs: LEUPROLIDE ACETATE reactions: Hot flush, Off label use, Prostatic specific antigen increased
+serious: 1 patientsex: 1 drugs: MEROPENEM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, CISPLATIN, DOXORUBICIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, PACLITAXEL, NEDAPLATIN reactions: Drug ineffective, Drug resistance, Intestinal obstruction, Metastases to pelvis, Metastases to lung
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Aspartate aminotransferase increased, Hypokalaemia
+serious: 1 patientsex: 2 drugs: CLONAZEPAM, LEVETIRACETAM, VALPROIC ACID reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PACLITAXEL, TRASTUZUMAB reactions: Cardiac failure, Cardiotoxicity
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOSPORINE, PREDNISOLONE reactions: Atypical Burkitts lymphoma, Anaemia, Diffuse large B-cell lymphoma, Gastric mucosal ulcer, Lymphadenopathy, Post transplant lymphoproliferative disorder, Renal impairment
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, CYCLOSPORINE, PREDNISOLONE reactions: Blood pressure increased, Foetal exposure during pregnancy, Proteinuria, Respiratory distress, Tachypnoea
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, BIPERIDEN, LITHIUM, RISPERIDONE reactions: Status epilepticus, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: PHENYTOIN reactions: Drug ineffective, Drug interaction
+serious: 1 patientsex: 2 drugs: ENTECAVIR, DOXORUBICIN HYDROCHLORIDE, GELATIN, HYDROCORTISONE, METRONIDAZOLE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Clostridium infection, Hepatic abscess
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, VINBLASTINE reactions: Drug intolerance, Drug resistance
+serious: 1 patientsex: 1 drugs: DASATINIB reactions: Skin depigmentation
+serious: 1 patientsex: 2 drugs: ALBUTEROL, ALPRAZOLAM, CALCITRIOL, BUMETANIDE, CALCIUM, FERROUS SULFATE, FLUTICASONE, OMEPRAZOLE, POTASSIUM BICARBONATE, TIZANIDINE HYDROCHLORIDE, VALSARTAN reactions: Acute kidney injury, Hypocalcaemia, Hyponatraemia, Leukocytosis, Metabolic acidosis, Rhabdomyolysis, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Hyponatraemia, Phaeohyphomycosis
+serious: 1 patientsex: 2 drugs: GEMCITABINEGEMCITABINE HYDROCHLORIDE, SUNITINIB MALATE reactions: Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic hormone secretion, Inappropriate antidiuretic
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Cholangitis, Drug-induced liver injury, Hepatitis allergic
+serious: 1 patientsex: 1 drugs: BISOPROLOL, BENIDIPINE, IMIDAPRIL, NICORANDIL, WARFARIN reactions: Drug interaction, Haematuria, International normalised ratio increased
+serious: 1 patientsex: 1 drugs: CLOFAZIMINE, DAPSONE, RIFAMPIN reactions: Abdominal pain, Crystal deposit intestine, Gastrointestinal disorder
+serious: 1 patientsex: 1 drugs: ASPIRIN, CARVEDILOL, EMPAGLIFLOZIN, HYDROCHLOROTHIAZIDE, INSULIN NOS, IPRATROPIUM BROMIDE, METFORMIN HYDROCHLORIDE, PANTOPRAZOLE SODIUM, ROSUVASTATIN, VALSARTAN reactions: Dehydration, Hypernatraemia, Hyperglycaemia, Hyponatraemia, Renal failure, Tachycardia
+serious: 1 patientsex: 2 drugs: IPILIMUMAB, NIVOLUMAB reactions: Hyperglycaemia, Type 1 diabetes mellitus
+serious: 1 patientsex: 2 drugs: ANAKINRA, HYDROXYCHLOROQUINE, METFORMIN HYDROCHLORIDE reactions: Long QT syndrome
+serious: 1 patientsex: 2 drugs: CINACALCET reactions: Pancreatitis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, TRIAMCINOLONE ACETONIDE reactions: Disease progression, Off label use, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, METHOTREXATE, MYCOPHENOLIC ACID, TOCILIZUMAB reactions: Chronic graft versus host disease, Sepsis
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Hepatitis, Myasthenia gravis, Myositis
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, CLINDAMYCIN, LEVOFLOXACIN, PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Drug intolerance, Jaundice, Hepatotoxicity
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, PREDNISOLONE, VINCRISTINE reactions: Cholangitis, Septic shock
+serious: 1 patientsex: 1 drugs: NITROUS OXIDE reactions: Vitamin B12 deficiency, Drug abuse
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CASPOFUNGIN, IMIPENEM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, TOBRAMYCIN, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: LITHIUM, MOCLOBEMIDE, PRIMIDONE, SERTRALINE HYDROCHLORIDE, VALPROIC ACID, VENLAFAXINE HYDROCHLORIDE reactions: Cognitive disorder, Cognitive disorder recurrent
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Malignant neoplasm progression, Metastases to central nervous system, Metastases to liver, Metastases to lung, Metastases to spine, Metastases to gastrointestinal tract, Metastases to skin, Metastases to pleura, Metastases to gastrointestinal tract, Metastases to skin, Metastases to liver, Metastases to gastrointestinal tract, Metastases to skin, Metastases to gastrointestinal tract, Metastases to skin, Metastases to gastrointestinal tract, Metastases to skin, Metastases to skin, Metastases to gastrointestinal tract, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin, Metastases to skin,
+serious: 1 patientsex: 2 drugs: GOLIMUMAB, HYDROXYCHLOROQUINE, LEFLUNOMIDE, PREDNISONE reactions: Pericardial effusion, Pericardial mass
+serious: 1 patientsex: 2 drugs: CALCITRIOL, CALCIUM CARBONATE, MAGNESIUM reactions: Drug ineffective, Hypocalcaemia, Hypomagnesaemia, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: LACOSAMIDE, LEVETIRACETAM, VALPROIC ACID reactions: Myoclonus, Off label use, Seizure
+serious: 1 patientsex: 2 drugs: ASPIRIN, CILOSTAZOL, HEPARIN SODIUM, WARFARIN reactions: Maternal exposure during pregnancy
+serious: 1 patientsex: 2 drugs: TOPIRAMATE reactions: Angle closure glaucoma, Cataract subcapsular
+serious: 1 patientsex: 1 drugs: CISPLATIN, IRINOTECAN reactions: Disseminated intravascular coagulation, Febrile neutropenia, Pantoea infection, Sepsis
+serious: 1 patientsex: 2 drugs: HALOPERIDOL, FAMOTIDINE, OLANZAPINE, SERTRALINE HYDROCHLORIDE reactions: Drug-induced liver injury, Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, DEXAMETHASONE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, TOBRAMYCIN reactions: Acute kidney injury, Renal failure
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, CIPROFLOXACIN, METRONIDAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, CAPTOPRIL, CITALOPRAM HYDROBROMIDE, ETANERCEPT, HYDROXYCHLOROQUINE, METHOTREXATE, PREDNISOLONE reactions: Ankylosing spondylitis, Diffuse systemic sclerosis, Scleroderma renal crisis
+serious: 1 patientsex: 2 drugs: GEMCITABINEGEMCITABINE HYDROCHLORIDE, ZOLEDRONIC ACID reactions: Cardiac failure, Left ventricular dysfunction
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: TRANILAST reactions: Cardiac arrest, Drug effective for unapproved indication, Off label use, Ventricular extrasystoles
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, IBUPROFEN, METHYLPREDNISOLONE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PREDNISONE, VANCOMYCIN reactions: Condition aggravated, Leukocytosis, Pneumonia, Pleural effusion, Sinus tachycardia
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE, PEGFILGRASTIM reactions: Drug ineffective, Febrile neutropenia
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Diverticulitis, Peritonitis, Respiratory failure
+serious: 1 patientsex: 2 drugs: BENZTROPINE, RISPERIDONE reactions: Dystonia, Extrapyramidal disorder, Respiratory acidosis
+serious: 1 patientsex: 2 drugs: CAPECITABINE, CISPLATIN, FLUOROURACIL reactions: Hepatic infarction, Metabolic encephalopathy
+serious: 1 patientsex: 2 drugs: DIAZOXIDE, GLUCAGON, OCTREOTIDE, SIROLIMUS reactions: Diarrhoea, Drug level below therapeutic, Hepatitis
+serious: 1 patientsex: 2 drugs: CETUXIMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN reactions: Steatohepatitis
+serious: 1 patientsex: 1 drugs: ISONIAZID, RIFAMPIN reactions: Tuberculosis
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, CYCLOPHOSPHAMIDE, DEXAMETHASONE, DOXORUBICIN, MELPHALAN, POMALIDOMIDE, VINCRISTINE reactions: Anaemia, Drug ineffective, Hepatitis B, Neutropenia, Pneumogenic septic shock, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ARSENIC TRIOXIDE, TRETINOIN reactions: Idiopathic intracranial hypertension
+serious: 1 patientsex: 1 drugs: PROPRANOLOL HYDROCHLORIDE reactions: Coma, Hypoglycaemia, Hypothermia, Hypotension, Pallor, Somnolence
+serious: 1 patientsex: 1 drugs: SODIUM POLYSTYRENE SULFONATE, SEVELAMER HYDROCHLORIDE reactions: Diverticulum, Intestinal perforation
+serious: 1 patientsex: 2 drugs: ABATACEPT, METHOTREXATE, PREDNISOLONE, SULFASALAZINE, TACROLIMUS, TOFACITINIB CITRATE reactions: Seborrhoeic keratosis, Squamous cell carcinoma
+serious: 1 patientsex: 1 drugs: DEXTROSE, INSULIN NOS, SODIUM CHLORIDE reactions: Cerebral oedema
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, FLUCYTOSINE, IMATINIB, PREDNISONE, VORICONAZOLE reactions: Condition aggravated, Drug ineffective, Hemiplegia, Meningitis cryptococcal, Pneumonitis, Respiratory failure
+serious: 1 patientsex: 1 drugs: ZINC reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, MYCOPHENOLATE MOFETIL, PREDNISOLONE, RITUXIMAB, TACROLIMUS reactions: Epstein-Barr virus infection, Leiomyosarcoma
+serious: 1 patientsex: 2 drugs: BROMOCRIPTINE, CABERGOLINE, ESTRADIOL, FOLIC ACID, GANIREX, LETROZOLE, MENOPUR, OXYCODONE, TYLENOL, VANCOMYCIN reactions: Maternal exposure during pregnancy, Normal newborn, Skin necrosis, Skin ulcer, Skin haemorrhage, Skin ulcer, Vascular herniation
+serious: 1 patientsex: 2 drugs: NATALIZUMAB reactions: Immune reconstitution inflammatory syndrome, Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 2 drugs: ASPIRIN, OXYGEN reactions: Retinal haemorrhage, Retinal vein occlusion
+serious: 1 patientsex: 2 drugs: EPINEPHRINE reactions: Accidental exposure to product, Device malfunction, Injection site injury, Injection site laceration, Injection site pain, Injection site injury, Injection site thigh, Injection site injury, Injection site pain, Injection site injury, Injection site pain, Injection site injury, Injection site pain, Injection site injury, Injection site pain, Injection site injury, Injection site pain, Injection site pain, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, Injection site discomfort, Injection site pain, In
+serious: 1 patientsex: 1 drugs: LEUPROLIDE ACETATE reactions: Pituitary apoplexy
+serious: 1 patientsex: 2 drugs: HEPARIN SODIUM, MYCOPHENOLATE MOFETIL, TACROLIMUS, WARFARIN reactions: Renal infarct
+serious: 1 patientsex: 2 drugs: ASPIRIN, DOBUTAMINEDOBUTAMINE HYDROCHLORIDE, EPINEPHRINE, FONDAPARINUX, GENTAMICIN, ISOPROTERENOL, MEROPENEM, METHYLPREDNISOLONE, NOREPINEPHRINE, TICAGRELOR reactions: Acute kidney injury, Atrioventricular block complete, Bradycardia, Cardiogenic shock, Circulatory collapse, Drug ineffective, Hypoperfusion, Hypoperfusion, Lactic acidosis, Oliguria, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Pericardial effusion, Upper gastrointestinal haemorrhage, Spinal cord injury, Spinal injury, Ventricular extrasystoles
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Glomerulonephritis membranoproliferative, Nephrotic syndrome
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID, DEXMEDETOMIDINE, ENOXAPARIN, HYDROXYCHLOROQUINE, MIDAZOLAM HYDROCHLORIDE, PYRITHRAMIDE reactions: Thrombotic stroke
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, CILOSTAZOL, INSULIN NOS, ROSUVASTATIN CALCIUM, TELMISARTAN reactions: Reversible cerebral vasoconstriction syndrome, Reversible cerebral vasoconstriction syndrome, Pre-eclampsia
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, MEROPENEM, METHYLPREDNISOLONE, PREDNISOLONE reactions: Herpes simplex, Oesophagitis, Pharyngotonsillitis
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Osteonecrosis
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZIDPYRAZINAMIDE, METOPROLOL, MOXIFLOXACIN, PREDNISONE, PYRAZINAMIDE, RIFAMPIN reactions: Acute kidney injury, Hepatitis, Multiple organ dysfunction syndrome, Septic shock
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN reactions: Gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: CARBIDOPAENTACAPONE, DOXYCYCLINE, RASAGILINE, ROTIGOTINE reactions: Depressed mood, Parkinsons disease, Sleep disorder
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, COGENTIN, CLONAZEPAM, PREDNISONE, RISPERIDONE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE reactions: Acute kidney injury, Confusional state, Hyperglycaemia, Memory impairment
+serious: 1 patientsex: 1 drugs: CYTARABINE, METHOTREXATE reactions: Hepatitis B reactivation
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ENOXAPARIN, HYDROXYCHLOROQUINE, METFORMIN HYDROCHLORIDE, NIFEDIPINE reactions: Drug ineffective, Gangrene, Respiratory failure
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, ASPIRIN, ATORVASTATIN, ACETAMINOPHEN, ATORVASTATIN CALCIUM, DICLOFENAC, MIRTAZAPINE, PERINDOPRIL, TIOTROPIUM BROMIDE reactions: Dementia with Lewy bodies, Fall, Ecchymosis, Fall rib, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall,
+serious: 2 patientsex: 1 drugs: ARIPIPRAZOLE, GUANFACINE, RISPERIDONE reactions: Apnoea-hypopnoea index increased, Hypersomnia
+serious: 1 patientsex: 1 drugs: GADOLINIUM reactions: Nephrogenic systemic fibrosis
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, ETOPOSIDE, HUMAN IMMUNOGLOBULIN G, LACOSAMIDE, LEVETIRACETAM, OLANZAPINE, VALPROIC ACID reactions: Febrile neutropenia, Septic shock
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, DOCETAXEL reactions: Nail toxicity, Palmar-plantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CALCIUM CARBONATE, FOLIC ACID, PREDNISONE, SIMVASTATIN, SPIRONOLACTONE, URSACOL reactions: Bacterial infection, Drug ineffective, Septic shock
+serious: 1 patientsex: 1 drugs: WARFARIN reactions: Gait disturbance, Gait disturbance
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Alopecia, Asthenia, Neutropenia, Thrombosis neck vein
+serious: 1 patientsex: 1 drugs: BRIVARICETAM reactions: Aggression, Cry, Dysarthria, Fall, Hypotonia, Social interaction disorder
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, DEXAMETHASONE, METRONIDAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BENZTROPINE, CLOZAPINE, LEVODOPA, METOCLOPRAMIDE, QUETIAPINE, TRIHEXYPHENIDYL reactions: Parkinsonism
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Acute myeloid leukaemia recurrent
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXIFLORTIDE, PACLITAXEL, ONDANSETRON reactions: Abdominal wall necrosis, Abdominal pain, Asthenia, Cachexia, Diarrhoea, Hypotension, Hypotension, Multiple organ dysfunction syndrome, Neutropenic colitis, Small intestinal perforation, Shock, Tachypnoea
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, AMPICILLIN, CEPHALEXIN, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CI
+serious: 1 patientsex: 2 drugs: FOLIC ACID, LAMOTRIGINE, LEVETIRACETAM reactions: Hypoglycaemia, Hyposthenia, Seizure
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Disease progression
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Paracoccidioidomycosis
+serious: 1 patientsex: 2 drugs: HEPARIN SODIUM reactions: Hyperhaemolysis syndrome
+serious: 1 patientsex: 1 drugs: CEFUROXIME, CLINDAMYCIN, DOXYCYCLINE, METRONIDAZOLE, MEROPENEM, VANCOMYCIN reactions: Drug hypersensitivity, Lemierres syndrome, Pulmonary embolism, Respiratory failure
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, POSACONAZOLE reactions: Anaemia, Neutropenia
+serious: 1 patientsex: 1 drugs: IBUPROFEN reactions: Compartment syndrome, Suicide attempt
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, DOCUSATE, LOSARTAN, OMEPRAZOLE, ZOLPIDEM TARTRATE reactions: Abdominal pain, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal pain lower, Abdominal pain upper, Abdominal
+serious: 1 patientsex: 2 drugs: CEPHALEXIN, CEFTRIAXONE reactions: Diarrhoea, Pregnancy test false positive
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, ARIPIPRAZOLE LAURATE reactions: Drug ineffective, Drug interaction, Treatment failure
+serious: 1 patientsex: 1 drugs: BUPRENORPHINE reactions: Drug resistance, Intentional product use issue, Intentional product use issue, Mental disorder, Post traumatic stress disorder
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PEMETREXED reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL reactions: Pneumatosis intestinalis
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN reactions: Optic pseudotumour
+serious: 1 patientsex: 2 drugs: EPOPOSTENOL, REMDESIVIR reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, CIPROFLOXACIN, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: MOXIFLOXACIN HYDROCHLORIDE, TIMOLOL reactions: Bacterial infection, Conjunctivitis
+serious: 1 patientsex: 2 drugs: BENZTROPINE, ESCITALOPRAM OXALATE, HALOPERIDOL, LEVOTHYROXINE, LORAZEPAM, METOPROLOL TARTRATE, PANTOPRAZOLE SODIUM, LOSARTAN, POTASSIUM CHLORIDE, TEMAZEPAM, RISPERIDONE, TEMOZOLOMIDE, TEMAZEPAM HYDROCHLORIDE, LOSARTAN, TEMAZEPAM HYDROCHLORIDE, TEMOZOLOMIDE, LOSARTAN, TEMAZEPAM HYDROCHLORIDE, TEMOZOLOMIDE, LOSARTAN, TEMAZEPAM, RISPERIDONE, TEMAZEPAM HYDROCHLORIDE, RISPERIDONE, TEMAZEPAM HYDROCHLORIDE, RISPERIDONE, TEMAZEPAM HYDROCHLORIDE, RISPERIDONE, TEMAZEPAM HYDROCHLOR
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, HEPARIN SODIUM, IBUPROFEN, METRONIDAZOLE, MEROPENEM, MORPHINE, NAFCILLIN, RANITIDINE, VANCOMYCIN reactions: Hypokalaemia
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Anaemia, Asthenia, Bone pain, Fatigue, Neutropenia, Off label use, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: MEDROXYPROGESTERONE ACETATE reactions: Deep vein thrombosis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN reactions: Atrial fibrillation
+serious: 1 patientsex: 1 drugs: LAMIVUDINE, PREDNISOLONE reactions: Myositis
+serious: 1 patientsex: 2 drugs: ACENOCOUMAROL, AMIODARONE, CAPTOPRIL, DIGOXIN, FUROSEMIDE, METOPROLOL, RAMIPRIL, SPIRONOLACTONE reactions: Hyperkalaemia
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ASPIRIN, CARVEDILOL, METHOTREXATE, PEGLUTICASE reactions: Anaemia haemolytic
+serious: 1 patientsex: 1 drugs: OSELTAMIVIR, MOXIFLOXACIN, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VORICONAZOLE reactions: Confusional state, Hallucination, visual
+serious: 1 patientsex: 2 drugs: CAPECITABINE, OXALIPLATIN reactions: Acute respiratory distress syndrome, Acute kidney injury, Ascites, Ascites fibrinous, Ascites hyaline membranes, Ascites, Cardiotoxicity, Diarrhoea, Diarrhoea, Dystelectasis, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic failure, Hepatic fibrosis, Hepatic failure, Hepatic steatosis, Hepatic failure, Hepatic failure, Hepatic fibrosis,
+serious: 1 patientsex: 2 drugs: CEFOTAXIME SODIUM reactions: Acute respiratory failure, Cerebral vasculitis, Generalised tonic-clonic seizure, Hemiplegia
+serious: 1 patientsex: 2 drugs: LEUPROLIDE ACETATE reactions: Multiple sclerosis
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Iridocyclitis, Ocular pain, Papillitis, Synechiae, Uveitis
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, CLONAZEPAM, FENTANYL, KETOROLAC TROMETHAMINE, KETOROLAC TROMETHAMINE HYDROCHLORIDE, KETOROLAC TROMETHAMINE HYDROCHLORIDE, LORAZEPAM, KETOROLAC TROMETHAMINE, OXYCODONE, QUETIAPINE, SEVOFLURANE reactions: Hypoxia
+serious: 1 patientsex: 1 drugs: CLOBAZAM, CLONIDINE, FELBAMATE, LITHIUM, PERPHENAZINE, QUETIAPINE, TRAZODONE HYDROCHLORIDE reactions: Drug interaction, Hypersomnia, Off balance, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: EFAVIRENZ, EMTRICITABINE, LISINOPRIL, TENOFOVIR reactions: Glomerulonephritis membranous
+serious: 1 patientsex: 1 drugs: EVEROLIMUS reactions: Diarrhoea, Fatigue, Interstitial lung disease, Nausea, Neutropenia, Vomiting
+serious: 1 patientsex: 2 drugs: SERTRALINE HYDROCHLORIDE reactions: Haemichorea
+serious: 1 patientsex: 1 drugs: CISPLATIN, ETOPOSIDE reactions: Anaemia, Haemoperitoneum, Hepatic artery ruptured
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Liver enzyme increased, Nausea
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, DOXORUBICIN, METHOTREXATE, VINCRISTINE reactions: Alveolar haemorrhage, Haemoptysis, Neutropenia, Septic shock
+serious: 1 patientsex: 2 drugs: ETHIODIZED OIL, OFLOXACIN, PYRAZINAMIDE, RIFAMPIN, STREPTOMYCINSTREPTOMYCIN SULFATE, VORICONAZOLE reactions: Adrenal insufficiency, Cerebral aspergillosis, Drug ineffective, Pyrexia, Seizure
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, FUROSEMIDE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN reactions: Intestinal obstruction, Mucosal inflammation
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, ISONIAZID, METHOTREXATE, ITRACONAZOLE reactions: Fungaemia, Neutropenia, Trichosporon infection
+serious: 1 patientsex: 2 drugs: DENOSUMAB, PANTOPRAZOLE SODIUM, SIMVASTATIN reactions: Gastroduodenitis, Gastrointestinal haemorrhage
+serious: 1 patientsex: 2 drugs: AFATINIB reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Off label use
+serious: 1 patientsex: 1 drugs: CEFEPIME HYDROCHLORIDE, LEVOFLOXACIN, ZOLPIDEM TARTRATE reactions: Oedema peripheral, Oedema peripheral
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE, PROPARACAINE HYDROCHLORIDE reactions: Drug abuse, Drug dependence, Iridocyclitis, Ocular hypopyon, Ophthalmic steroid disorder, Visual acuity reduced
+serious: 1 patientsex: 2 drugs: AFATINIB reactions: Decreased appetite, Fatigue, Nausea, Rash, Stomatitis
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, BUSULFAN, CYCLOSPORINE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE, CYCLOSPORINE HYDROCHLORIDE,
+serious: 1 patientsex: 2 drugs: EMPAGLIFLOZIN, INSULIN GLARGINE, METFORMIN HYDROCHLORIDE reactions: Diabetic ketoacidosis
+serious: 1 patientsex: 1 drugs: ANAKINRA, ETANERCEPT, CYCLOSPORINE, DAPSONE, METHOTREXATE, PREDNISOLONE reactions: Drug effect incomplete, Injection site reaction
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, METHYLPREDNISOLONE, PREDNISOLONE reactions: Cytomegalovirus enterocolitis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Burkitts lymphoma, Febrile neutropenia, Neutropenia, Pneumonia, Pyrexia, Rash, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: ASPARAGINASE, DAUNORUBICIN, METHOTREXATE, PREDNISONE, VINCRISTINE reactions: Hydrocephalus
+serious: 1 patientsex: 2 drugs: PROPYLTHIOURACIL reactions: Lupus-like syndrome, Pulmonary alveolar haemorrhage, Respiratory failure
+serious: 1 patientsex: 2 drugs: ALBUTEROL, AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, FLUTICASONE PROPIONATESALMETEROL XINAFOATE, METHYLPREDNISOLONE, METOPROLOL SUCCINATE, RITUXIMAB, TORSEMIDE reactions: Cardiogenic shock, Drug ineffective, Myocarditis aspergillus, Renal failure
+serious: 2 patientsex: 1 drugs: PRIMIDONE, PROPRANOLOL HYDROCHLORIDE, TOPIRAMATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, PREDNISOLONE, SQUARIAC ACID DIBUTYLESTER reactions: Osteonecrosis of the femur
+serious: 1 patientsex: 2 drugs: TACROLIMUS reactions: Idiopathic intracranial hypertension
+serious: 1 patientsex: 2 drugs: ZOLEDRONIC ACID reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, EPIRUBICIN, KETOCONAZOLE, RAMIPRIL, OCTREOTIDE reactions: Febrile neutropenia, Intestinal perforation, Psychotic disorder
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Basal cell carcinoma, Cryptococcal cutaneous infection, Drug ineffective, Granulomatous inflammation, Infection, Skin lesion, Skin ulcer, Skin plaque, Skin plaque, Skin scar
+serious: 1 patientsex: 1 drugs: ASPIRIN, CYCLOPHOSPHAMIDE, DEXAMETHASONE, METHYLPREDNISOLONE, PREDNISONE, VALACYCLOVIR HYDROCHLORIDE reactions: Cystoid macular oedema, Drug ineffective, Retinal haemorrhage, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Hydronephrosis, Nephrolithiasis, Pyrexia, Renal tract calculus
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, CEFOTAXIME SODIUM, GOSERELIN, HYDROXYCHLOROQUINE, LOPINAVIRRITONAVIR, MEROPENEM, NOREPINEPHRINE, PREDNISOLONE, TOCILIZUMAB reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: BETAMETHASONE, MAGNESIUM, PREDNISONE reactions: Foetal exposure during pregnancy, Premature baby, Thrombotic thrombocytopenic purpura
+serious: 1 patientsex: 2 drugs: LINEZOLID, LEVOFLOXACIN, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Tendon disorder
+serious: 1 patientsex: 2 drugs: ALENDRONATE SODIUM, LANTHANUM CARBONATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYTARABINE, METHOTREXATE reactions: Aplasia, Bone marrow failure, Pancytopenia, Respiratory failure, Stenotrophomonas infection
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, ETOPOSIDE, IFOSFAMIDE, RITUXIMAB reactions: Cellulitis, Febrile neutropenia, West Nile viral infection
+serious: 1 patientsex: 1 drugs: MEDROXYPROGESTERONE ACETATE, TIZANIDINE, THORIODAZINE reactions: Priapism
+serious: 1 patientsex: 2 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, DEXAMETHASONE, EMAPALAMAB, FLUDARABINE PHOSPHATE, METHYLPREDNISOLONE, PREDNISONE, THIOTEPA, THYMOCYTE IMMUNE GLOBULIN NOS reactions: Polymyositis
+serious: 1 patientsex: 1 drugs: OLANZAPINE, QUETIAPINE, SERTRALINE HYDROCHLORIDE, TOPIRAMATE reactions: Priapism
+serious: 1 patientsex: 2 drugs: FOLIC ACID reactions: Folate deficiency, Unmetabolised folate syndrome
+serious: 1 patientsex: 2 drugs: ASPIRIN, BUDESONIDE, CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Meningioma
+serious: 1 patientsex: 2 drugs: FINGOLIMOD HYDROCHLORIDE reactions: Herpes zoster
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, WARFARIN reactions: Acute respiratory failure, Pulmonary alveolar haemorrhage
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE, METHYLPHENIDATE HYDROCHLORIDE reactions: Weight increased
+serious: 1 patientsex: 2 drugs: ALBUTEROL, NICARDIPINE reactions: Acute pulmonary oedema, Back pain, Headache, Hypoventilation, Photophobia, Visual disorder
+serious: 1 patientsex: 1 drugs: BASILIXIMAB, ETANERCEPT, MYCOPHENOLATE MOFETIL reactions: Graft versus host disease
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL reactions: Aortic pseudoaneurysm, Cough haemorrhagic, Haematemesis, Leukocytosis, Pneumonia, Respiratory failure, Septic shock
+serious: 2 patientsex: 1 drugs: ALPRAZOLAM, CLONAZEPAM, HYDROXYZINE HYDROCHLORIDE, MIRTAZAPINE, SERTRALINE HYDROCHLORIDE, VENLAFAXINE HYDROCHLORIDE reactions: Drug dependence, Drug intolerance, Major depression, Suicidal ideation
+serious: 1 patientsex: 2 drugs: CLOZAPINE, TETRABENAZINE reactions: Hallucination, Suicidal ideation
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, VINBLASTINE reactions: Interstitial lung disease
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, FRAXIPARINE, LORAZEPAM, PIPERIDOPRIL HYDROCHLORIDE, ROSUVASTATIN reactions: Acute respiratory failure, Pericardial effusion
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Organising pneumonia
+serious: 1 patientsex: 2 drugs: AMIODARONE, BISOPROLOL, INSULIN NOS, LIDOCAINE, MEROPENEM, NOREPINEPHRINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CILOSTAZOL, HYDROCHLOROTHIAZIDE, HEPARIN SODIUM, TRICLOPIDINE reactions: Haematoma muscle
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Anaemia, Fatigue, Hepatitis C, Insomnia
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE reactions: Atypical mucoepidermoid carcinoma, Gingival hypertrophy
+serious: 1 patientsex: 2 drugs: MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS, VALGANCICLOVIR reactions: Acrophaeohyphomycosis, Brain abscess, Neutropenia
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, NIVOLUMAB reactions: Hypophysitis, Multiple organ dysfunction syndrome, Secondary adrenocortical insufficiency
+serious: 1 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Blindness transient, Lactic acidosis
+serious: 1 patientsex: 1 drugs: CISPLATIN, DEXAMETHASONE, DOXORUBICIN HYDROCHLORIDE, IFOSFAMIDE reactions: Neutropenia
+serious: 1 patientsex: 2 drugs: APATINIB reactions: Palmar-plantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, AMLODIPINE BESYLATE, IBUPROFEN, METHOTREXATE reactions: Abdominal pain, Decreased appetite, Nausea, Pancytopenia, Stomatitis, Skin ulcer, Vomiting
+serious: 1 patientsex: 2 drugs: CEFUROXIME reactions: Lichen planus
+serious: 1 patientsex: 1 drugs: FUROSEMIDE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISOLONE reactions: Osteonecrosis, Myopathy, Vertebral fracture
+serious: 1 patientsex: 1 drugs: CYTARABINE, DAUNORUBICIN reactions: Optic neuropathy, Maculopathy
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, CALCIOPTRIOL, CYCLOSPORINE, METHOTREXATE reactions: Malaise
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, TRABECTEDIN reactions: Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alan
+serious: 1 patientsex: 1 drugs: SILDENAFIL reactions: Cardiac failure, Cardiomegaly, Drug use issue
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, MERCAPTOPURINE, METHOTREXATE, IMATINIB MESYLATE reactions: Constipation, Febrile neutropenia, Pneumonia
+serious: 1 patientsex: 2 drugs: BINIMETINIB reactions: Acne, Drug resistance, Eye pressure increased, Myalgia, Retinopathy
+serious: 1 patientsex: 2 drugs: PEMBROLIZUMAB reactions: Pancytopenia
+serious: 1 patientsex: 1 drugs: NATALIZUMAB reactions: Cytomegalovirus infection
+serious: 1 patientsex: 1 drugs: ASPIRIN, GLYCERIN, ISOSORBIDE DINITRATE, METFORMIN HYDROCHLORIDE reactions: Bradycardia, Confusional state, Lactic acidosis, Shock
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, FLUCONAZOLE reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Rectal haemangioma
+serious: 1 patientsex: 1 drugs: AMIKACIN, CIDOFOVIR, CYCLOSPORINE, DEXAMETHASONE, FOSCARNET, GANCICLOVIR, OCTREOTIDE, VANCOMYCIN reactions: Drug ineffective, Drug resistance, Multiple organ dysfunction syndrome, Shock
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, HEPARIN SODIUM, METRONIDAZOLE, WARFARIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Acute kidney injury, Autoimmune hepatitis, Eosinophilia, Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, GOLIMUMAB, LEFLUNOMIDE, METHOTREXATE, PREDNISONE, SULFASALAZINE reactions: IgA nephropathy
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE reactions: Febrile neutropenia, Oral stomatitis, Pancytopenia
+serious: 1 patientsex: 1 drugs: SERTRALINE HYDROCHLORIDE reactions: Apnoia, Exposure during pregnancy, Neonatal abstinence syndrome, Skin colour pale, Skin opacity, Vomiting
+serious: 1 patientsex: 1 drugs: TACROLIMUS reactions: Inflammatory bowel disease
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, LEUPROLIDE ACETATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, PYRIDOSTIGMINE reactions: Drug ineffective, Multiple organ dysfunction syndrome, Respiratory failure
+serious: 1 patientsex: 2 drugs: LACOSAMIDE, KETAMINE, MIDAZOLAM HYDROCHLORIDE, PHENYTOIN, TOPIRAMATE, PROPOFOL reactions: Drug-induced liver injury, Off label use
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, ENOXAPARIN, PREDNISONE reactions: Pulmonary embolism
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Acute kidney injury, Glomerulonephritis, Tubulointerstitial nephritis
+serious: 1 patientsex: 2 drugs: DIAZEPAM, OLANZAPINE, VALPROIC ACID reactions: Anaemia, Drug ineffective, Hypercholesterolaemia, Maternal exposure during pregnancy, Psychomotor hyperactivity, Sedation, Treatment noncompliance
+serious: 1 patientsex: 1 drugs: AMIODARONE, DIGOXIN, LEVOFLOXACIN, MEROPENEM, METHYLPREDNISOLONE, PENICILLIN G reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CABERGOLINE reactions: Drug resistance, Rhinorrhoea
+serious: 1 patientsex: 1 drugs: ASPIRIN, BUDESONIDE, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CI
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, METHOTREXATE reactions: Antiandrogen withdrawal syndrome
+serious: 1 patientsex: 1 drugs: ALENDAZOLE, CARBAMAZEPINE, DEXAMETHASONE, PRAZIQUANTEL reactions: Conjunctival hyperaemia, Drug ineffective, Eye pain, Ocular cysticercosis, Pain in eye, Seizure
+serious: 1 patientsex: 2 drugs: CLONAZEPAM, CITALOPRAM HYDROBROMIDE, FENTANYL, OXYCODONE HYDROCHLORIDE reactions: Constipation
+serious: 1 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Vitamin B12 deficiency
+serious: 1 patientsex: 2 drugs: ASPIRIN, CABERGOLINE, CYDROGESTERONE, ESTRADIOL reactions: Drug ineffective, Ovarian hyperstimulation syndrome
+serious: 1 patientsex: 2 drugs: IBUPROFEN reactions: Pulmonary hypertension
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Acute kidney injury, Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: CISPLATIN, SODIUM THIOSULFATE reactions: Osteonecrosis
+serious: 1 patientsex: 1 drugs: FUROSEMIDE, SPIRONOLACTONE, TOLVAPTAN reactions: Drug ineffective, Drug interaction, Hepatic cirrhosis, Hepatic oedema, Hepatic cirrhosis recurrent, Hepatic cirrhosis, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, Hepatic cirrhosis recurrent, He
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE reactions: Bradycardia, Hypercalcaemia, Hypotension, Intentional overdose, Pancreatitis, Suicide attempt
+serious: 1 patientsex: 1 drugs: COLISTIN, MEROPENEM, TIGECYCLINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, DOXYCYCLINE, MEROPENEM, OSELTAMIVIR, TEICOPLANIN reactions: Candida infection, Nocardiosis, Respiratory failure
+serious: 1 patientsex: 2 drugs: BROMOCRIPTINE reactions: Amenorrhoea, Arthralgia, Drug ineffective, Fatigue, Pituitary microadenoma, Raynauds phenomenon, Weight decreased
+serious: 1 patientsex: 2 drugs: METHADONE HYDROCHLORIDE reactions: Accidental exposure to product by child, Electrocardiogram QT prolonged, Loss of consciousness, Miosis, Somnolence, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, WARFARIN reactions: Drug interaction, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased
+serious: 1 patientsex: 1 drugs: CLOBETASOL PROPIONATE reactions: Adrenal insufficiency, Adrenal suppression, Adrenal suppression induced, Adrenal insufficiency, Adrenal suppression, Adrenal insufficiency, Adrenal suppression, Adrenal insufficiency, Adrenal suppression, Adrenal insufficiency, Adrenal suppression, Adrenal insufficiency, Adrenal insufficiency, Adrenal suppression, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency, Adrenal insufficiency,
+serious: 1 patientsex: 1 drugs: ACENOCOUMAROL, ATORVASTATIN, ENOXAPARIN, INSULIN NOS, LEVOTHYROXINE, METOPROLOL, LISINOPRIL, METOPROLOL SUCCINATE, SPIRONOLACTONE, SIMVASTATIN reactions: Acute kidney injury, Drug interaction, Gastrointestinal haemorrhage, Non-ST segment elevation myocardial infarction
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, DEXAMETHASONE, MEROPENEM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: LEVOFLOXACIN reactions: Skin hyperpigmentation
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Alopecia, Asthenia, Bone pain, Dyspnoea, Fatigue, Hepatic enzyme increased, Hepatic function abnormal, Metastases to central nervous system, Nausea, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia, Neutropenia,
+serious: 1 patientsex: 1 drugs: CARBOPLATIN reactions: Malignant neoplasm progression
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE reactions: Aortopulmonary artery malformation, Foetal exposure during pregnancy
+serious: 1 patientsex: 2 drugs: HUMAN THYMOCYTE IMMUNE GLOBULIN reactions: Hypothyroidism, Thyroiditis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CARBOPLATIN, PACLITAXEL reactions: Atelectasis, Malignant neoplasm progression, Metastases to central nervous system, Seizure, Tumour lysis syndrome
+serious: 1 patientsex: 1 drugs: PREDNISOLONE, TACROLIMUS reactions: Dengue fever, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: CISPLATIN, PACLITAXEL reactions: Bone marrow failure
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, DEXAMETHASONE, FAVIPIRAVIR, PIPERACILLIN SODIUMTAZOBACTAM SODIUM reactions: Acute kidney injury, Acute respiratory distress syndrome, Acute kidney injury, Acute kidney injury, Cardiac arrest, Hepatitis fulminant, Multiple organ dysfunction syndrome, Myocarditis, Off label use, Product use in unapproved indication, Systemic inflammatory response syndrome
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Pancytopenia
+serious: 1 patientsex: 2 drugs: CIDOFOVIR, MEFLOUINE, MIRTAZAPINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: MILTEFOSINE reactions: Iridocyclitis
+serious: 1 patientsex: 1 drugs: DALBAVANCIN reactions: Off label use, Renal impairment
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL reactions: Immunodeficiency
+serious: 1 patientsex: 2 drugs: AMIODARONE HYDROCHLORIDE, WARFARIN reactions: Pulmonary alveolar haemorrhage, Pulmonary toxicity
+serious: 1 patientsex: 1 drugs: QUETIAPINE, VALPROIC ACID reactions: Akathisa, Drug abuse, Dyskinesia, Myoclonus, Neurotoxicity, Restlessness
+serious: 1 patientsex: 2 drugs: ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, FOLIC ACID, CITALOPRAM HYDROBROMIDE, LEVOTHYROXINE, RANITIDINE, ZOPICLONE reactions: Electrocardiogram QT prolonged, Torsade de pointes
+serious: 1 patientsex: 1 drugs: AFATINIB reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ATORVASTATIN CALCIUM reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: PREDNISOLONE, TACROLIMUS reactions: Peripheral T-cell lymphoma, Splenomegaly
+serious: 1 patientsex: 2 drugs: SORAFENIB reactions: Rash
+serious: 1 patientsex: 1 drugs: ASPIRIN, CIPROFLOXACIN, FUROSEMIDE, LEVOFLOXACIN, METOPROLOL, SIMVASTATIN reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: ACENOCOUMAROL, AMLODIPINE BESYLATE reactions: Subdural haematoma
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, ETOPOSIDE, HUMAN IMMUNOGLOBULIN G, RITUXIMAB, VALACYCLOVIR HYDROCHLORIDE reactions: Anaemia, C-reactive protein increased, Cough, Cough pyramidal, C-reactive protein increased, Cough, Cough opacity, C-reactive protein increased, C-reactive protein increased, C-reactive protein increased, Cough, C-reactive protein increased, C-reactive protein increased, Cough, C-reactive protein increased, C-reactive protein increased, Cough, Cough, C-reactive protein increased, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, Cough, C
+serious: 1 patientsex: 2 drugs: PEMBROLIZUMAB reactions: Disease progression
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Haemorrhage
+serious: 1 patientsex: 1 drugs: METHADONE HYDROCHLORIDE reactions: Acute kidney injury, Drug abuse, Hypotension, Myoclonus, Respiratory failure, Somnolence
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE reactions: Tumour lysis syndrome, Wound perforation
+serious: 1 patientsex: 1 drugs: CETUXIMAB, FLUOROURACIL, ENTECAVIR, NIVOLUMAB, PREDNISOLONE reactions: Drug resistance, Hepatitis
+serious: 1 patientsex: 2 drugs: BOTULINUM TOXIN TYPE A reactions: Botulism, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, BISOPROLOL, INSULIN NOS, LISINOPRIL reactions: Cytomegalovirus infection, Drug ineffective, Toxic epidermal necrolysis
+serious: 1 patientsex: 1 drugs: CANADINE HYDROCHLORIDE, GLIPIZIDE, INSULIN NOS, METFORMIN HYDROCHLORIDE reactions: Diabetic ketoacidosis
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, HYDROXYCHLOROQUINE, LEVETIRACETAM, METFORMIN HYDROCHLORIDE reactions: Acute kidney injury, Ischaemic stroke
+serious: 1 patientsex: 2 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Mediastinal haemorrhage
+serious: 1 patientsex: 2 drugs: CYTARABINE, DASATINIB reactions: Pancreatitis acute
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, CLAVULANIC ACID, METRONIDAZOLE reactions: Toxic encephalopathy
+serious: 1 patientsex: 1 drugs: GEMCITABINE reactions: Haematemesis
+serious: 1 patientsex: 2 drugs: CHLORAMBUCIL, CYCLOSPORINE, FUROSEMIDE, MYCOPHENOLIC ACID, PREDNISONE reactions: Cytomegalovirus colitis
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: BK virus infection, Basal cell carcinoma, Bladder adenopathy, Haematuria, Urothelial adenocarcinoma, Ureteric adenopathy, Urosepsis
+serious: 1 patientsex: 1 drugs: ESTRAMUSTINE reactions: Cardiac failure
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, AZATHIOPRINE, INFLIXIMAB, MESALAMINE, METRONIDAZOLE, PREDNISONE, THALIDOMIDE reactions: Schizophrenia
+serious: 1 patientsex: 2 drugs: DENOSUMAB, PACLITAXEL, TRASTUZUMAB, ZOLEDRONIC ACID reactions: Cardiotoxicity, Drug ineffective, Neuropathy peripheral
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENMETOCLOPRAMIDE, CINNARIZINE, DIMENHYDRAMINE, METOCLOPRAMIDE reactions: Toxic epidermal necrolysis
+serious: 1 patientsex: 2 drugs: ASPIRIN, BETAXOLOL, BUDESONIDE, CYCLOPHOSPHAMIDE, HYDROCORTISONE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Drug ineffective for unapproved indication, Off label use
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE HYDROCHLORIDE, CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Drug resistance, Infection, Lymphadenopathy, Night sweats, Night sweats abnormal, Night sweats
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, ACETAMINOPHENCLAVULANIC ACID, ACETAMINOPHENCLAVULANIC ACID, DICLOFENAC, CEFTAZIDIME, ENOXAPARIN, TRAMADOL reactions: Dermatitis bullous, Haemorrhagic
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, DOCETAXEL reactions: Interstitial lung disease
+serious: 1 patientsex: 2 drugs: ASPIRIN, BIOTIN, LISINOPRIL, METOPROLOL, ZINC reactions: Anaemia, Copper deficiency, Cytopenia
+serious: 1 patientsex: 1 drugs: GLATIRAMER ACETATE reactions: Bone marrow failure, Myelotoxicity
+serious: 1 patientsex: 1 drugs: CLONIDINE, EPLERENONE, FINASTERIDE, FUROSEMIDE, TAMULOSIN, WARFARIN reactions: Anaemia, Bronchospasm, Coagulopathy, Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Cerebral toxoplasmosis, Cytomegalovirus infection, Epstein-Barr virus infection, Pneumonia cytomegaloviral
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, FLUOROURACIL reactions: Aspergillus infection, Small intestinal infarction
+serious: 1 patientsex: 2 drugs: DOXORUBICIN HYDROCHLORIDE, IFOSFAMIDE reactions: Nausea, Leukopenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, PREDNISONE, LANREOTIDE reactions: Anaemia, Fatigue, Renal impairment
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE, RIVAROXABAN reactions: Drug ineffective, Joint pain
+serious: 1 patientsex: 2 drugs: CALCIUM, MAGNESIUM reactions: Condition aggravated, Drug ineffective
+serious: 1 patientsex: 1 drugs: CO2 reactions: Abdominal pain, Abdominal pain upper, Abdominal pain lower, Cat scratch colon, Bladder, Urine, Peritoneal disorder, Pneumoperitoneum, Serosal tear, Urine output decreased
+serious: 1 patientsex: 2 drugs: BUPROPION, DULOXETINE, INSULIN GLARGINE, MIRTAZAPINE, PRAZOSIN, TRAZODONE HYDROCHLORIDE reactions: Drug ineffective, Hypoglycaemia, Intentional overdose, Suicide attempt
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, METFORMIN HYDROCHLORIDE reactions: Exposure during pregnancy, Hepatic enzyme increased, Premature delivery, Respiratory distress
+serious: 1 patientsex: 1 drugs: BACLOFEN reactions: Drug dependence, Drug withdrawal syndrome, Drug dependence
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, MYCOPHENOLIC ACID, PREDNISONE, USTEKINUMAB reactions: Gastrointestinal disorder, Hypertension, Swelling
+serious: 1 patientsex: 2 drugs: OMEPRAZOLE, SITAGLIPTIN reactions: Autoimmune hepatitis, Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: NITISINONE reactions: Acute hepatic failure, Cognitive disorder
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Acute kidney injury, Atrial arrhythmia, Hypotension, Listeriosis, Peritonitis bacterial
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, PREDNISOLONE, VINCRISTINE reactions: COVID-19
+serious: 1 patientsex: 2 drugs: MEROPENEM, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug ineffective, Hyponatraemia
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, FLUDARABINE PHOSPHATE, INFLIXIMAB, METHOTREXATE, METHYLPREDNISOLONE, THIOTEPA reactions: Hepatic failure, Graft versus host disease in skin, Hepatic failure, Hepatic encephalopathy, Neurotoxicity, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: APXABAN, CABOZANTINIB, NIVOLUMAB, PAZOPANIB reactions: Duodenal ulcer, Upper gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE reactions: Drug abuse, Hypertension, Myocardial infarction, Seizure
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENTRAMADOL reactions: Osteoarthritis progressive
+serious: 1 patientsex: 2 drugs: CALCITRIOL, CALCIUM, CALCIUM CARBONATE, CALCIUM CHLORIDE, CALCIUM FLUDROCORTISONE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBONATE, CALCIUM CARBON
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, PREDNISONE reactions: Drug abuse, Gastrointestinal disorder, Headache
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, HEPARIN SODIUM, METOPROLOL TARTRATE, LISINOPRIL, WARFARIN reactions: Haemorrhagic infarction, Headache, Oedema vasogenic, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, LEVETIRACETAM, METFORMIN HYDROCHLORIDE, TEMOZOLOMIDE reactions: Drug ineffective, Pulmonary embolism
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, IRINOTECAN, TEMOZOLOMIDE reactions: Bone marrow failure, Diarrhoea, Pyrexia, Respiratory failure
+serious: 1 patientsex: 1 drugs: LITHIUM, OLANZAPINE, RISPERIDONE reactions: Acute kidney injury, Delirium, Drug interaction, Nephropathy toxic, Neurotoxicity, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Cardiomegaly, Interventricular septal hypertrophy
+serious: 1 patientsex: 1 drugs: OCRIPLASMIN reactions: Macular hole, Serous retinal detachment
+serious: 1 patientsex: 2 drugs: CLINDAMYCIN reactions: Erythema, Off label use, Product use issue
+serious: 1 patientsex: 2 drugs: ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, METOPROLOL, TICAGRELOR reactions: Myalgia
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL, TRASTUZUMAB reactions: Cerebral artery embolism, Jaundice
+serious: 1 patientsex: 2 drugs: CHOLECALCIFEROL, MAGNESIUM, MYCOPHENOLATE MOFETIL, PREDNISOLONE, RANITIDINE, SULFAMETHOXAZOLETRIMETHOPRIM, TACROLIMUS reactions: Acute kidney injury, Biliary obstruction, Drug level increased, Delirium, Hypertension, Nausea, Vomiting, Visual impairment, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: FENTANYL, MORPHINE, TRAMADOL reactions: Drug ineffective, Drug withdrawal syndrome, Drug ineffective, Drug tolerance increased
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, CERTOLIZUMAB PEGOL, METHOTREXATE, PREDNISONE reactions: Drug ineffective, Psoriatic arthropathy
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Acute myocardial infarction
+serious: 1 patientsex: 1 drugs: CALCIUM, DOCETAXEL, EPROSARTAN, FELODIPINE, GOSERELIN, SIMVASTATIN reactions: Atrial fibrillation, Fatigue, Palpitations, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: MESALAMINE, PREDNISONE reactions: Atelectasis, Myocarditis
+serious: 1 patientsex: 1 drugs: CETUXIMAB, CISPLATIN, FLUOROURACIL reactions: Disease progression, Drug ineffective, Oedema peripheral, Oedema peripheral, Tracheal stenosis
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, ASPIRIN, TRIPTORELIN, TAMOXIFEN reactions: Brain hypoperfusion, Hemichorea, Hemiballism
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Drug dependence, Nephrotic syndrome
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE
+serious: 1 patientsex: 2 drugs: HYDROCORTISONE, TACROLIMUS reactions: Drug ineffective, Haemolytic uraemic syndrome, Pneumococcal infection, Respiratory failure
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, FLUCONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: PREDNISONE, TACROLIMUS reactions: Hepatocellular carcinoma
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, CARBAMAZEPINE, DEXMEDETOMIDINE, FLURBIPROFEN, LEVETIRACETAM, MIDAZOLAM HYDROCHLORIDE, PHENYTOIN, ROCURONIUM BROMIDE, SEVOFLURANE, VALPROIC ACID reactions: Drug ineffective, Status epilepticus
+serious: 1 patientsex: 2 drugs: ORLISTAT reactions: Acute kidney injury, Nephropathy oxalate
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Focal segmental glomerulosclerosis
+serious: 1 patientsex: 1 drugs: INSULIN GLARGINE, INSULIN LISPRO reactions: Amyloidosis, Hypoglycaemia, Subcutaneous haemorrhage
+serious: 1 patientsex: 1 drugs: AMIKACIN, COLISTIN, MEROPENEM, VANCOMYCIN reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: PREDNISONE reactions: Angioedema acquired, Condition aggravated, Haematuria, Proteinuria, Supraventricular tachycardia
+serious: 1 patientsex: 1 drugs: AMIODARONE HYDROCHLORIDE reactions: Pulmonary toxicity
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Disease progression
+serious: 2 patientsex: 2 drugs: IBUPROFEN reactions: Drug interaction
+serious: 1 patientsex: 1 drugs: BASILIXIMAB, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS, VALGANCICLOVIR reactions: Aspergillus infection, Cytomegalovirus enterocolitis, Neutropenia
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, AFLIBERCEPT, RANIBIZUMAB reactions: Macular degeneration
+serious: 1 patientsex: 1 drugs: TRETINOIN reactions: Thrombocytosis
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, FENPYROXIME, VALPROIC ACID reactions: Gastrointestinal toxicity, Intentional product misuse, Metabolic acidosis, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DARUNAVIR, EMTRICITABINERILPIVIRINE, RALTEGRAVIR, RITONAVIR reactions: Drug ineffective, Hepatitis B, Immune dysfunction, Prescribed underdose
+serious: 1 patientsex: 2 drugs: ISONIAZID, NIFEDIPINE, THIOTINE reactions: Reversible cerebral vasoconstriction syndrome
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DEXAMETHASONE, DOXORUBICIN, LINEZOLID, METRONIDAZOLE, RITUXIMAB, VINDESINE reactions: Drug ineffective, Respiratory failure
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, HYDROXYCHLOROQUINE reactions: Dyspnoea, Pulmonary embolism, Pulmonary venous thrombosis
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, ETOPOSIDE reactions: Acute kidney injury, Haemophagocytic lymphohistiocytosis, Hepatic failure, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: LEVOTHYROXINE, METFORMIN HYDROCHLORIDE reactions: Acute kidney injury, Anuria, Metabolic acidosis, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, ENOXAPARIN, TENECTEPLASE reactions: Spinal epidural haematoma
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Hyponatraemia, Nausea, Paraneoplastic syndrome
+serious: 1 patientsex: 2 drugs: BEPOTASTINE BESILATE reactions: Drug hypersensitivity, Urticaria
+serious: 1 patientsex: 2 drugs: DOXORUBICIN, IFOSFAMIDE, TRABECTEDIN reactions: Haematotoxicity, Malignant neoplasm progression
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Cardiogenic shock, Chest haematoma, Mediastinal haemorrhage
+serious: 1 patientsex: 2 drugs: SITAGLIPTIN PHOSPHATE reactions: Diabetic ketoacidosis, Diabetic ketoacidosis
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, HEPARIN SODIUM, GEMFILZIL reactions: Drug ineffective, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: MYTHILLERIDONE reactions: Aeruginosa infection, Brain abscess, Nocardiosis
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, MESALAMINE, PREDNISOLONE reactions: Diffuse large B-cell lymphoma, Intestinal abscess, Necrotising proctitis, Perirectal abscess, Sepsis
+serious: 1 patientsex: 1 drugs: BUSULFAN, FLUDARABINE PHOSPHATE, METHYLPREDNISOLONE reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: DARUNAVIR, RALTEGRAVIR, RITONAVIR reactions: Toxic encephalitis
+serious: 1 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE, PREDNISOLONE reactions: Thrombotic thrombocytopenia
+serious: 1 patientsex: 1 drugs: ACETAMINOPHENHYDROCODONE, GABAPENTIN, HYDROCODONE BITARTRATE reactions: Aggression, Depression, Drug ineffective, Intentional overdose, Suicide attempt
+serious: 1 patientsex: 2 drugs: AMISULPRIDE, HYDROXYZINE HYDROCHLORIDE, PROTHIPENDYL, TRAZODONE HYDROCHLORIDE, ZOLPIDEM TARTRATE reactions: Haemorrhage intracranial, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: ACYCLOVIR, CARBOPLATIN, DEXAMETHASONE, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE, PREDNISOLONE reactions: Disease recurrence, Visual acuity reduced
+serious: 1 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Anxiety, Hypotension, Lactic acidosis, Suicide attempt, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Acute kidney injury, Haematotoxicity
+serious: 1 patientsex: 2 drugs: ALFACALCIDOL, CINACALCET HYDROCHLORIDE reactions: Hypercalcaemia, Hyperphosphataemia
+serious: 1 patientsex: 2 drugs: EVEROLIMUS, METHYLPREDNISOLONE, SIROLIMUS reactions: Acute fibrinous and organizing pneumonia
+serious: 1 patientsex: 1 drugs: HYDROCORTISONE reactions: Coma, Hypoglycaemia, Hypovolaemic shock, Hypoxia, Toxic encephalopathy
+serious: 1 patientsex: 2 drugs: PACLITAXEL reactions: Peripheral sensory neuropathy
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, METHYLPREDNISOLONE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Atrioventricular block complete, Dizziness, Dyspnoea, Electrocardiogram QRS complex abnormal, Electrocardiogram tachycardia, Lymphopenia, Neutrophilia, Sinus bradycardia, Syncope
+serious: 2 patientsex: 2 drugs: CLONAZEPAM, LEVETIRACETAM, SODIUM OXYBATE, TOPIRAMATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALEMTUZUMAB, GLATIRAMER ACETATE, NATALIZUMAB reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: DOCETAXEL, GEMCITABINE reactions: Disease progression
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, PREDNISOLONE, TRASTUZUMAB reactions: Maternal exposure during pregnancy, Premature delivery, Septic shock
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS reactions: Acute respiratory failure, Anaemia, Arrhythmia, Cardiac arrest, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: DESFLURANE, GLYCOPYRROLATE, PENTOTHAL SODIUM, REMIFENTANIL, ROCURONIUM BROMIDE reactions: Wernickes encephalopathy
+serious: 1 patientsex: 2 drugs: MITOMYCIN reactions: Pterygium recurrence
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE, OLANZAPINE, QUETIAPINE, SERTRALINE HYDROCHLORIDE reactions: Drug ineffective, Insomnia, Hallucination, auditory, auditory hallucination, auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditory auditory, auditor
+serious: 1 patientsex: 1 drugs: CANDESARTAN, WARFARIN reactions: Hyponatraemia, Status epilepticus
+serious: 1 patientsex: 2 drugs: ASPIRIN, METHIMAZOLE reactions: Pancreatitis acute
+serious: 1 patientsex: 2 drugs: CAPECITABINE, LAPATINIB reactions: Arteriospasm coronary
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CIPROFLOXACIN, FLUCONAZOLE, HUMAN IMMUNOGLOBULIN G, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Cytomegalovirus infection, Fungal infection, Pneumonia, Sepedonium infection
+serious: 1 patientsex: 1 drugs: NOREPINEPHRINE reactions: Cardiac arrest, Drug ineffective, Tumour lysis syndrome
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, DOXORUBICIN, METHOTREXATE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Respiratory distress
+serious: 1 patientsex: 2 drugs: NITROFURANTOIN reactions: Atypical pneumonic cystic hyperplasia, Pneumonia aspiration
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFTAZIDIME, CLINDAMYCIN, HYDROXYCHLOROQUINE, RIBAVIRIN, OSELTAMIVIR, PREDNISOLONE reactions: Acute generalised exanthematous pustulosis
+serious: 1 patientsex: 2 drugs: FINGOLIMOD, YELLOW FEVER ANTIGEN reactions: Immune reconstitution inflammatory syndrome, Multiple sclerosis relapse
+serious: 1 patientsex: 2 drugs: FLUTICASONE PROPIONATESALMETEROL XINAFOATE, METHYLPREDNISOLONE reactions: Bacteraemia, Acute kidney injury
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, HYDROCHLOROTHIAZIDE, METFORMIN HYDROCHLORIDE, SIMVASTATIN reactions: Anaemia normochromic, Gastric hyperaemia, Eosinophilia, Gastrointestinal disorder, Helicobacter infection, Weight decreased
+serious: 1 patientsex: 1 drugs: EFAVIRENZ, LAMIVUDINE, NEVIRAPINE, STAVUDINE reactions: Pathogen resistance
+serious: 1 patientsex: 1 drugs: MITOMYCIN reactions: Conjunctival filtering bleb, Intraocular pressure increased, Ocular epithelial failure
+serious: 1 patientsex: 2 drugs: AFLIBERCEPT reactions: Choroidal neovascularisation, Macular hole
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANATE POTASSIUM, SUCRALFATE SODIUM reactions: Odynophagia, Oesophageal ulcer
+serious: 1 patientsex: 2 drugs: MILRINOTECAN, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: VANCOMYCIN reactions: Acute kidney injury
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, PREDNISOLONE, QUINOLONE reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: APIXABAN reactions: Arteriovenous malformation, Subdural haematoma
+serious: 1 patientsex: 1 drugs: VERAPAMIL HYDROCHLORIDE reactions: Cardiogenic shock, Hypotension, Overdose, Sinus arrest, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Teratoma
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE reactions: Intentional overdose, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: CEFOPORAZONESULBACTAM, COLISTIN, HYDROCORTISONE, METHYLPREDNISOLONE reactions: Bartters syndrome
+serious: 1 patientsex: 1 drugs: BASILIXIMAB, EVEROLIMUS, PREDNISOLONE, TACROLIMUS reactions: Acute kidney injury, Kaposis sarcoma
+serious: 1 patientsex: 1 drugs: ADEFOVIR DIPIVOXIL reactions: Fanconi syndrome acquired, Nephropathy
+serious: 1 patientsex: 1 drugs: LEVOFLOXACIN, FURAZOLIDINE, RABEPRAZOLE reactions: Toxic epidermal necrolysis
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, TIROFIBAN reactions: Drug ineffective, Drug resistance
+serious: 1 patientsex: 2 drugs: BACLOFEN reactions: Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE reactions: Adrenal hyperplasia, Cushings syndrome, Ectopic adrenal hormone secretion, Hypokalaemia, Off label use, Product use in unapproved indication, Weight decreased
+serious: 1 patientsex: 2 drugs: PEGINTERFERON ALFA-2A, RIBAVIRIN, SOFOSBUVIR reactions: Anaemia, Gluteus abscess, Leukopenia, Lymphadenopathy, Lymph node tuberculosis, Night sweats, Pyrexia, Tuberculosis
+serious: 1 patientsex: 2 drugs: ATOOSIBAN, MORPHINE, OXYCODONE HYDROCHLORIDE, NEFOPAM reactions: Foetal exposure during pregnancy, Megacystis jirovecii pneumonia, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: AMIODARONE, EPINEPHRINE, MAGNESIUM, LIDOCAINE, SODIUM CHLORIDE reactions: Drug ineffective, Ventricular fibrillation
+serious: 1 patientsex: 1 drugs: FENOFIBRATE, FLUNITRAZEPAM, LAMIVUDINE, LEVOMEPROMAZINE, SERTRALINE HYDROCHLORIDE, QUAZEPAM, RALTEGRAVIR, ZIDOVUDINE reactions: Diabetes mellitus
+serious: 1 patientsex: 2 drugs: BUDESONIDE, DACLIZUMAB, MERCAPTOPURINE, PREDNISOLONE reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: CAPECITABINE, PHENYTOIN reactions: Drug interaction, Drug level increased, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: FOLIC ACID, METHOTREXATE, TOFACITINIB CITRATE reactions: Herpes zoster
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, LINEZOLID, TOBRAMYCIN reactions: Gastrointestinal disorder
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Hepatic enzyme increased
+serious: 1 patientsex: 1 drugs: CYTARABINE, FLUDARABINE PHOSPHATE, IDARUBICIN reactions: Bacterial infection, Febrile neutropenia, Pseudomonas infection, Sepsis
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, BUSULFAN, CYCLOSPORINE, FLUDARABINE PHOSPHATE, METHOTREXATE, THIOTEPA, VALGANCICLOVIR reactions: Cytomegalovirus chorioretinitis, Cytomegalovirus infection, Cytomegalovirus vasculitis, Cytomegalovirus infection reactivation, Retinal haemorrhage, Retinal vasculitis, Retinal necrosis, Retinal haemorrhage, Retinal vasculitis, Retinal necrosis, Retinal haemorrhage, Retinal necrosis, Retinal haemorrhage, Retinal necrosis, Retinal haemorrhage, Retinal necrosis, Retinal haemorrhage, Retinal necrosis, Retinal haemorrhage, Retinal necrosis, Retinal haemorrhage, Ret
+serious: 1 patientsex: 2 drugs: BISOPROLOL, FLECAINIDE, HYDROXYZINE HYDROCHLORIDE, LORATADINE reactions: Torsade de pointes, Ventricular fibrillation
+serious: 1 patientsex: 1 drugs: CLOZAPINE, OLANZAPINE, QUETIAPINE, RISPERIDONE reactions: Electrocardiogram QT prolonged
+serious: 1 patientsex: 2 drugs: DOCETAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Charcot-Marie-Tooth syndrome
+serious: 1 patientsex: 2 drugs: FOLATE SODIUM, VALPROIC ACID reactions: Foetal anticonvulsant syndrome, Polyhydramnios
+serious: 1 patientsex: 2 drugs: BISOPROLOL, FUROSEMIDE, SPIRONOLACTONE reactions: Ischaemic stroke
+serious: 1 patientsex: 1 drugs: CLOZAPINE, LITHIUM, OLANZAPINE, VALPROIC ACID reactions: Pancreatitis acute
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, IXAZOMIB, LENALIDOMIDE, ZOLEDRONIC ACID reactions: Cutaneous necrotising vasculitis
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Cytomegalovirus colitis, Retinitis
+serious: 1 patientsex: 2 drugs: DOCETAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Malignant neoplasm, Metastases to liver, Metastases to lung
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Pancytopenia
+serious: 1 patientsex: 2 drugs: LEVONORGESTREL reactions: Device dislocation
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, BUSPIRONE HYDROCHLORIDE, CLOPIDOGREL BISULFATE, METOPROLOL SUCCINATE, THIAMINE reactions: Angioedema
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISONE reactions: Chorioretinitis, Condition aggravated, Retinal detachment, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: AMISULPRIDE, BIPERIDEN, LORAZEPAM, PROPRANOLOL HYDROCHLORIDE, RISPERIDONE reactions: Akathisia, Drug withdrawal syndrome, Dystonia, Pneumonia aspiration
+serious: 1 patientsex: 1 drugs: RIVAROXABAN reactions: Cardiac failure, Constrictive pericarditis
+serious: 1 patientsex: 2 drugs: TOPOTECAN HYDROCHLORIDE reactions: Meningitis
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: Acute kidney injury, Cardiac arrest, Chronic kidney disease, Shock, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE, BRENTUXIMAB VEDOTIN reactions: Acute kidney injury
+serious: 1 patientsex: 1 drugs: ALENDRONATE SODIUM, CALCITRIOL, CALCIUM, CALCIUM CHLORIDE, CALCIUM SULFATE, CALCIUM CARBONATE, CALCIUM PHOSPHATE, CALCIUM CARBONATEVITAMIN D NOS reactions: Blood parathyroid hormone increased, Hypocalcaemia
+serious: 1 patientsex: 2 drugs: TEMOZOLOMIDE reactions: Central nervous system neurocytoma
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, TACROLIMUS reactions: Drug ineffective, Nocardiosis
+serious: 1 patientsex: 2 drugs: FLUOXETINE HYDROCHLORIDE reactions: Anxiety, OCD, auditory hallucination, Suicidal ideation
+serious: 1 patientsex: 2 drugs: TEMOZOLOMIDE reactions: Maternal exposure during pregnancy
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Arthritis, Fasciitis, Immune-mediated adverse reaction
+serious: 1 patientsex: 2 drugs: ACYCLOVIR, CEFEPIME HYDROCHLORIDE, LEVOFLOXACIN, MAGNESIUM FUNGIN, POSACONAZOLE, PENTAMIDINE reactions: Cellulosimicrobium infection, Pneumonia
+serious: 1 patientsex: 1 drugs: DOCETAXEL, PREDNISONE reactions: Death, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ARSENIC TRIOXIDE reactions: Bone marrow fibrosis
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, INFLIXIMAB reactions: Crohns disease
+serious: 1 patientsex: 2 drugs: CINACALCET HYDROCHLORIDE reactions: Drug intolerance, Hypercalcaemia, Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN reactions: Acute kidney injury, Hepatic necrosis, Hepatic toxicity, Overdose, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, LISINOPRIL reactions: Drug ineffective, Hepatic fibrosis, Hepatic steatosis
+serious: 1 patientsex: 2 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Acute graft versus host disease, Nausea, Pericardial effusion, Pneumonia, Vomiting
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE reactions: COVID-19
+serious: 1 patientsex: 1 drugs: CYTARABINE, FLUDARABINE PHOSPHATE, IDARUBICIN, HYDROXYUREA, FLUDARABINE PHOSPHATE, IMATINIB, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VORICONAZOLE reactions: Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Bronchopulmonary aspergillosis, Broncho
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, CISPLATIN, GEMCITABINE, PACLITAXEL reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CAPECITABINE, TEMOZOLOMIDE, TORIPALIMAB reactions: Drug resistance, Genotype drug resistance test positive
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE reactions: Autoimmune hepatitis
+serious: 1 patientsex: 2 drugs: DOXORUBICIN HYDROCHLORIDE, ETHIODIZED OIL reactions: Cerebral embolism
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, METHOTREXATE, TACROLIMUS reactions: Graft versus host disease, Infection, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: HUMAN IMMUNOGLOBULIN G reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 2 drugs: CELECOXIB, DULOXETINE, ESOMEPRAZOLE MAGNESIUM, METHADONE HYDROCHLORIDE, OXYCODONE, PREGABALIN reactions: Serotonin syndrome
+serious: 1 patientsex: 1 drugs: ENOXAPARIN reactions: Drug-induced liver injury
+serious: 1 patientsex: 2 drugs: ALEDRONIC ACID reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 2 drugs: AMITRIPTYLINE, CODEINE, FLUCLOXACILLIN, METRONIDAZOLE, PHENOXYMETHYLPENICIN reactions: Abdominal pain, Abdominal discomfort, Irritable bowel syndrome, Intestinal infection, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: LOSARTAN, NITROFURANTOIN, TROPPIUM CHLORIDE reactions: Organising pneumonia
+serious: 1 patientsex: 1 drugs: CASPOFUNGIN ACETATE, CILASTATIN SODIUM, IMIPENEM, METHIMAZOLE, VANCOMYCIN reactions: Aspergillus infection, Cough, Cough is aggravated, Cough is recurrent, Cough is aggravated, Cough is recurrent, Cough is aggravated, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent, Cough is recurrent
+serious: 1 patientsex: 2 drugs: ERYTHROMYCIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, METOCLOPRAMIDE, OMEPRAZOLE, QUININE SULFATE, ZOPICLONE reactions: Chest infection, Diarrhoea, Fatigue, Phlebitis, Sore mouth
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, CETIRIZINE HYDROCHLORIDE, DEXAMETHASONE, PANTOPRAZOLE SODIUM, THALIDOMIDE reactions: Acute kidney injury, Acute respiratory distress syndrome, Anaemia, Acute kidney injury, Acute kidney injury, Anaemia, Leukocytosis, Thrombocytopenia, Toxic epidermal necrolysis
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, CYCLOPHOSPHAMIDE, DOXORUBICIN, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN HYDROCHLORIDE, FOSPHENYTOIN, LEVETIRACETAM, METHOTREXATE, VINCRISTINE reactions: Cerebral infarction, Drug ineffective
+serious: 1 patientsex: 1 drugs: GLYCOPYRROLATE, OXYGEN, SEVOFLURANE, THIOPENTAIL reactions: Cyanosis, Dyspnoea, Lip oedema, Post procedural croup, Stridor
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM, LIMACPROST, PRAVASTATIN, WARFARIN reactions: Cholestasis, Drug ineffective, Renal failure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, PREDNISONE, RITUXIMAB reactions: Aspergillus infection, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, ETOPOSIDE, PEGLASTA reactions: Bradycardia
+serious: 1 patientsex: 2 drugs: GLANTAMINE, MEMANTIN, SURVEXANT reactions: Parkinsonism, Pleurothotonus
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, HYDROXYCHLOROQUINE, PREDNISOLONE reactions: Arthritis, Escherichia infection, Meningitis bacterial, Sacroiliitis
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, FENTANYL, KETAMINE, MIDAZOLAM HYDROCHLORIDE, HYALURONDASE, XYLOCAINE reactions: Blood glucose increased, Drug ineffective, Hypotension, Sedation
+serious: 1 patientsex: 1 drugs: METHIMAZOLE reactions: Lupus-like syndrome, Immunoglobulin A deficiency
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, ELTROMBOPAG, PRASUGREL HYDROCHLORIDE, UROKINASE, ZOTARIUM reactions: Acute coronary syndrome, Coronary artery stenosis, Coronary artery thrombosis
+serious: 1 patientsex: 1 drugs: CALCIUM CARBONATE, CYCLOSPORINE, FUROSEMIDE, LANSOPRAZOLE, HEPARIN SODIUM, MIZORIBINE, PREDNISOLONE, WARFARIN reactions: Calciphylaxis, Drug ineffective, Psuedomonas infection
+serious: 1 patientsex: 2 drugs: HUMIRA, PREDNISONE reactions: Mycobacterium avium complex infection
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, PREDNISOLONE reactions: Neuro-Sweet disease
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, CLONAZEPAM, HALOPERIDOL, IMIPRAMINE, PAROXETINE, PALIPERIDONE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: MIRTAZAPINE reactions: Sedation
+serious: 1 patientsex: 1 drugs: OLANZAPINE reactions: Major depression, Treatment noncompliance
+serious: 1 patientsex: 1 drugs: ALFUZOSIN, FINASTERIDE, GABAPENTIN, INSULIN NOS, METFORMIN HYDROCHLORIDE, MYCOPHENOLIC ACID, PREDNISONE, RANIBIZUMAB, VILDAGLIPTIN reactions: Alveolar proteinosis, Cough, Dyspnoea exertional, Pulmonary alveolar proteinosis, Weight decreased
+serious: 1 patientsex: 1 drugs: ABIRATERONE ACETATE, BICALUTAMIDE, LEUPROLIDE ACETATE, ZOLEDRONIC ACID reactions: Anaemia, Fatigue, Nail disorder, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: TACROLIMUS reactions: Central nervous system lymphoma
+serious: 1 patientsex: 2 drugs: CISPLATIN, PACLITAXEL reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, FLUTICASONE PROPIONATESALMETEROL XINAFOATE, OMALIZUMAB, MOMETASONE FUROATE HYDROCHLORIDE, PREDNISOLONE, SALMETEROL XINAFOATE reactions: Anaemia, Bone marrow failure, Cytopenia, Dysplasia, Hypoplastic marrow, Pancytopenia, Respiratory disorder
+serious: 1 patientsex: 1 drugs: ASPIRIN, WARFARIN reactions: Haemolytic anaemia, Heparin-induced thrombocytopenia
+serious: 1 patientsex: 1 drugs: ATENOLOL, DULOXETINE HYDROCHLORIDE, METFORMIN HYDROCHLORIDE reactions: Lichenoid keratosis
+serious: 1 patientsex: 1 drugs: BETAMETHASONE, CELESTRETE, METHYLDOPA, PRAZOSIN reactions: Exposure during pregnancy, Premature rupture of oesophageal wall
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, CLOMIPRAMINE, MIRTAZAPINE, RISPERIDONE, VENLAFAXINE HYDROCHLORIDE reactions: Neuroleptic malignant syndrome, Serotonin syndrome
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Haematotoxicity
+serious: 1 patientsex: 2 drugs: ETHINYL ESTRADIOLDROSPIRENONE reactions: Abortion spontaneous, Deep vein thrombosis
+serious: 1 patientsex: 2 drugs: ANASTROZOLE, CARBOPLATIN, PEMETREXED reactions: Disease progression, Metastases to lymph nodes, Respiratory failure
+serious: 1 patientsex: 1 drugs: AMPICILLIN, CYCLOPHOSPHAMIDE, DEXAMETHASONE, HYDROXYCHLOROQUINE, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, FILGRASTIM, VINBLASTINE reactions: Hodgkins disease recurrent
+serious: 1 patientsex: 2 drugs: QUETIAPINE, VALPROIC ACID reactions: Hypothyroidism, Ileus paralytic
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, LEVOFLOXACIN, METHYLPREDNISOLONE, PYRAZINAMIDE, RIFAMPIN reactions: Immune reconstitution inflammatory syndrome, Upper gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: ACETAMINOPHENHYDROCODONE, CITALOPRAM HYDROBROMIDE, FOLIC ACID, INFLIXIMAB, NAPROXEN, TRAMADOL reactions: Eosinophilic fasciitis, Urticaria
+serious: 1 patientsex: 2 drugs: ALBUTEROL, DEXAMETHASONE, SODIUM CHLORIDE reactions: Hypotension, Lactic acidosis
+serious: 1 patientsex: 2 drugs: DACTINOMYCIN, LEUCOVORIN, METHOTREXATE reactions: Drug ineffective, Drug resistance, Neoplasm recurrence
+serious: 1 patientsex: 2 drugs: EZETIMIBE, ROSUVASTATIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: LEVOFLOXACIN, RAMIPRIL, SIMVASTATIN reactions: Delirium
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, MEROPENEM, MOXIFLOXACIN, TACROLIMUS reactions: Abdominal pain, Diarrhoea, Drug level above therapeutic, Enterococcal infection, Fungaemia, Nausea, Pyrexia, Renal impairment
+serious: 1 patientsex: 2 drugs: CAPECITABINE, EVEROLIMUS, TEMOZOLOMIDE reactions: Disease progression
+serious: 1 patientsex: 2 drugs: PROTAMINE SULFATE reactions: Acute pulmonary hypertension, Acute kidney injury, Right ventricular failure, Pulmonary hypertension
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ASPIRIN, LANSOPRAZOLE, LOSARTAN, WARFARIN reactions: Oesophageal haematoma
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G reactions: Exposure during pregnancy, Haemolytic anaemia
+serious: 1 patientsex: 1 drugs: CAPTOPRIL, HYDROXYCHLOROQUINE, METFORMIN HYDROCHLORIDE reactions: COVID-19, Multiple organ dysfunction syndrome, Respiratory disorder
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, LENALIDOMIDE, METHOTREXATE reactions: Acute lymphocytic leukaemia, Gene mutation, Gastrointestinal toxicity
+serious: 1 patientsex: 2 drugs: DOCETAXEL reactions: Generalised tonic-clonic seizure
+serious: 1 patientsex: 2 drugs: METHENAMINE HYDROCHLORIDE, NITROFURANTOIN reactions: Urinary tract infection bacterial
+serious: 1 patientsex: 1 drugs: BUDESONIDE, METHYLPREDNISOLONE, MESALAMINE, PANTOPRAZOLE SODIUM reactions: Anaemia, Drug ineffective, Haemorrhage
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID, FENTANYL, ISOFLURANE, MAGNESIUM SULFATE, NITROUS OXIDE, PROPOFOL, VECURONIUM BROMIDE reactions: Drug interaction, Exposure during pregnancy, Neuromuscular block prolonged
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Dysphagia, Paraplegia, Visual impairment
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, DEGARELIX reactions: Hot flush, Erectile dysfunction, Libido decreased, Sexual dysfunction
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, GENTAMICIN, RIFAMPIN, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, CLOMIPRINE, INSULIN NOS, METFORMIN HYDROCHLORIDE, NIFEDIPINE, VENLAFAXINE HYDROCHLORIDE reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: VERAPAMIL HYDROCHLORIDE reactions: Off label use
+serious: 1 patientsex: 2 drugs: GONADANTROPIN, METHYLPREDNISOLONE reactions: Abortion spontaneous, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, METHOTREXATE, PREDNISONE reactions: Eczema, Off label use
+serious: 1 patientsex: 2 drugs: BOSUTINIB, DASATINIB, IMATINIB MESYLATE reactions: Diarrhoea, Drug ineffective, Rash
+serious: 1 patientsex: 2 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, DOXORUBICIN, IFOSFAMIDE, MELPHALAN, VINCRISTINE reactions: Drug ineffective, Meningeal disorder, Pericardial effusion
+serious: 1 patientsex: 1 drugs: EPINEPHRINE, HYDROXYETHYLENE SODIUM, INSULIN NOS, POTASSIUM CHLORIDE, SODIUM BICARBONATE reactions: Osmotic demyelination syndrome, Type 1 diabetes mellitus
+serious: 1 patientsex: 1 drugs: ALBUTEROL, AMINOPHYLLINE, ALBUTEROL SUCCINATE, MAGNESIUM SULFATE, METHYLPREDNISOLONE, IPRATROPIUM BROMIDE reactions: Hypotension, Status asthmaticus
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, RITUXIMAB reactions: Adenovirus infection, Multiple organ dysfunction syndrome, Pancytopenia
+serious: 1 patientsex: 1 drugs: DENOSUMAB, FELVESTRAN, LEUPROLIDE ACETATE reactions: Diarrhoea, Fatigue, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, LEVOFLOXACIN, PYRAZINAMIDE, RIFAMPIN reactions: Ocular toxicity
+serious: 1 patientsex: 2 drugs: CISPLATIN, FLUOROURACIL reactions: Bladder perforation
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Neuropathy peripheral
+serious: 1 patientsex: 2 drugs: ETOPOSIDE reactions: Renal failure
+serious: 1 patientsex: 2 drugs: HEPARIN SODIUM, WARFARIN reactions: Drug ineffective, Exposure during pregnancy, Therapeutic response decreased
+serious: 1 patientsex: 1 drugs: EPOPROSTENOL, FUROSEMIDE, PROSTACYCLINE reactions: Pulmonary oedema
+serious: 1 patientsex: 2 drugs: LENVATINIB reactions: Cerebral artery dissection
+serious: 1 patientsex: 2 drugs: CHLORPHENIRAMINE, LEVOCETIRIZINE, PREDNISOLONE reactions: Anaphylactic reaction
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, COMPAZINE, TORADOL reactions: Encephalitis viral, Renal failure, Varicella zoster virus infection
+serious: 1 patientsex: 1 drugs: HYDROMORPHONE reactions: Acute kidney injury, Hypertension, Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: DOBUTAMINEDOBUTAMINE HYDROCHLORIDE, LIDOCAINE, MILRINONE, MAGNESIUM, TACROLIMUS reactions: Hypomagnesaemia, Ventricular tachycardia
+serious: 1 patientsex: 1 drugs: CRIZOTONIB reactions: Gangrene, Neurological decompensation, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: LETROZOLE reactions: Hypercalcaemia
+serious: 1 patientsex: 2 drugs: MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Calcineuria, Haematuria, Parathyroid hormone increased, Stress fracture
+serious: 1 patientsex: 1 drugs: FENTANYL reactions: Laryngospasm
+serious: 1 patientsex: 2 drugs: ASPIRIN, CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VITAMINS reactions: Diabetic ketoacidosis, Diabetes insipidus, Hypothyroidism, Insulin-dependent diabetes mellitus, Weight increased
+serious: 1 patientsex: 1 drugs: ATEZOLIZUMAB reactions: Meningitis aseptic
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Hypersensitivity, Neuropathy peripheral
+serious: 1 patientsex: 2 drugs: VALPROIC ACID reactions: Acute hepatic failure, Encephalopathy, Mitochondrial toxicity
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, FENTANYL, MIDAZOLAM HYDROCHLORIDE, PROPOFOL, TRANEXAMIC ACID reactions: Accidental exposure to product, Apnoea, Drug ineffective, Hypertension, Metabolic acidosis, Myoclonus, Myoclonus
+serious: 1 patientsex: 2 drugs: FUROSEMIDE, MAGNESIUM SULFATE reactions: Hyperkalaemia, Hypocalcaemia
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUCONAZOLE reactions: Treatment failure
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Acute coronary syndrome, Gastrointestinal haemorrhage, Hepatic function abnormal, Hepatitis E, Lower gastrointestinal haemorrhage
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Paradoxical drug reaction
+serious: 1 patientsex: 1 drugs: NITROGLYCERIN reactions: Acute myocardial infarction
+serious: 1 patientsex: 1 drugs: ABIRATERONE, DOCETAXEL reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CISPLATIN, ETOPOSIDE reactions: Nausea, Neutropenia, Vomiting
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, PERINDOPRIL, PROPRANOLOL HYDROCHLORIDE reactions: Aortic dissection, Pneumatosis intestinalis, Pneumoperitoneum
+serious: 1 patientsex: 2 drugs: BISOPROLOL, ENTECAVIR, FUROSEMIDE, LOVASTATIN, HYDROCORTISONE, SPIRONOLACTONE, VERAPAMIL HYDROCHLORIDE reactions: Adrenal insufficiency
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Catatonia
+serious: 1 patientsex: 2 drugs: FUROSEMIDE, RITUXIMAB, PREDNISOLONE reactions: Acute respiratory distress syndrome, Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Cachexia, Neutropenia, Pancytopenia
+serious: 1 patientsex: 2 drugs: WARFARIN reactions: Anaemia, Haemothorax
+serious: 1 patientsex: 2 drugs: DOXORUBICIN, MITOMYCIN reactions: Neutrophil count decreased
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, BUPIVACAINE, CEFAZOLIN, KETOPROFEN, NEFOPAM, POVIDONE-IODINE, SODIUM CHLORIDE reactions: Meningitis aseptic
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DEXAMETHASONE, DOXORUBICIN, METHYLPREDNISOLONE, ZOLEDRONIC ACID reactions: Constipation, Neuropathy peripheral, Lethargy
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CYCLOPHOSPHAMIDE, DOXORUBICIN, METHOTREXATE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Anaemia, Drug reaction with eosinophilia and systemic symptoms, Febrile neutropenia, Nausea, Oral mucosal inflammation, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: VORICONAZOLE reactions: Cunninghamella infection, Neutropenia
+serious: 1 patientsex: 2 drugs: CARBIDOPAENTACAPONELEVODOPA, RASAGILINE MESYLATE reactions: Hypoglycaemia
+serious: 1 patientsex: 1 drugs: ERLOTINIB, METHOTREXATE reactions: Haemoptysis, Hepatic function abnormal, Metastases to liver, Myelosuppression, Product use in unapproved indication, Small cell lung cancer
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CISPLATIN, DOCETAXEL, ETOPOSIDE, OXALIPLATIN reactions: Alopecia, Asthenia, Bone pain, Dyspnoea, Fatigue, Haemorrhage, Infection, Nausea, Neutropenia, Ovarian cancer, Ovarian toxicity, Pain, Pain in extremity, Pyrexia, Rash, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash maculo-papular, Rash macul
+serious: 1 patientsex: 1 drugs: CALCIUM CARBONATE, CHOLECALCIFEROL, CYCLOSPORINE, IBANDRONATE SODIUM, MYCOPHENOLATE MOFETIL reactions: Aortic calcification, Back pain, Back pain, Chronic kidney disease, Drug ineffective, Drug interaction, Femoral neck fracture, Ibandronate, Ischaemic nephropathy, Joint fracture, Joint calcification, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture, Joint fracture
+serious: 1 patientsex: 1 drugs: KETOCONAZOLE, ITRACONAZOLE, POSACONAZOLE, VORICONAZOLE reactions: Torsade de pointes
+serious: 1 patientsex: 2 drugs: DICLOFENAC reactions: Haematoma, Pyomyositis, Staphylococcal infection
+serious: 1 patientsex: 1 drugs: ATORVASTATIN, BICALUTAMIDE, DOCETAXEL, GLIPIZIDE, METFORMIN HYDROCHLORIDE, TADAFIL reactions: Haematuria
+serious: 1 patientsex: 2 drugs: PROPYLTHIOURACIL reactions: Anti-neutrophil cytoplasmic antibody positive vasculitis, Otitis media
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, IXAZOMIB, LENALIDOMIDE reactions: Acute kidney injury
+serious: 1 patientsex: 2 drugs: PAZOPANIB reactions: Acute kidney injury, Urosepsis, Pneumonitis
+serious: 1 patientsex: 1 drugs: CARBOPLATIN reactions: Generalised tonic-clonic seizure
+serious: 1 patientsex: 1 drugs: ASPIRIN, CYCLOPENTOLATE, PHENYLEPHRINE HYDROCHLORIDE, WARFARIN reactions: Intraocular pressure decreased
+serious: 1 patientsex: 2 drugs: NEVIRAPINE reactions: Acute HIV infection
+serious: 1 patientsex: 1 drugs: BRENTUXIMAB VEDOTIN, CISPLATIN, CYTARABINE, DEXAMETHASONE, PEGFILGRASTIM reactions: Anaemia, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ECULIZUMAB reactions: Abdominal pain, Abdominal pain
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, FLUCONAZOLE, ITRACONAZOLE, OXYGEN reactions: Acute kidney injury, Coccidioidomycosis, Septic shock
+serious: 1 patientsex: 1 drugs: ASPIRIN reactions: Cardiac arrest, Overdose, Shock
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE, RITUXIMAB reactions: Drug ineffective, Klebsiella infection
+serious: 1 patientsex: 2 drugs: NATALIZUMAB reactions: Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 2 drugs: CLOPIDOGREL BISULFATE reactions: Quadriparesis
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Blepharoematoma, Facial oedema, Fall, Subarachnoid haemorrhage
+serious: 1 patientsex: 2 drugs: FORICETISONE, PROPRANOLOL HYDROCHLORIDE reactions: Hypertensive emergency, Phaeochromocytoma
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Atrial mass, Cerebral infarction, Embolic stroke
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, ETORICOXIB, PREGABALIN, TRAMADOL reactions: Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: ESCITALOPRAM OXALATE, LORAZEPAM, MIRTAZAPINE, PROPRANOLOL HYDROCHLORIDE, ZOLPIDEM TARTRATE reactions: Delirium, Withdrawal syndrome
+serious: 1 patientsex: 2 drugs: KETAMINE HYDROCHLORIDE reactions: Abdominal pain lower, Drug abuse, Haematuria, Klebsiella infection, Pyelonephritis
+serious: 1 patientsex: 1 drugs: METOPROLOL reactions: Acute respiratory failure, Chest wall weakness, Mitochondrial disorder
+serious: 1 patientsex: 1 drugs: LEVOFLOXACIN, OSELTAMIVIR, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: DABRAFENIB, IPILIMUMAB, METFORMIN HYDROCHLORIDE, PEMBROLIZUMAB, VEMURAFENIB, TRAMETINIB reactions: Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: MODAFINIL reactions: Drug dependence, Drug use disorder, Irritability, Sleep disorder, Tremor
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, ETANERCEPT, CERTOLIZUMAB PEGOL reactions: Sarcoidosis
+serious: 1 patientsex: 2 drugs: CLONAZEPAM, URSODIOL reactions: Atrioventricular block, Bradycardia, Cardiomegaly, Hypoalbuminaemia, Hypothyroidism, Renal impairment, Sinus node dysfunction, Sinus node dysfunction
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CARBOPLATIN, DEXAMETHASONE, ETOPOSIDE, FILGRASTIM, IFOSFAMIDE, METHOTREXATE reactions: Disease recurrence, Seizure
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Cytopenia, Drug level increased, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: BISOPROLOL, CANDESARTAN reactions: Foetal exposure during pregnancy, Hypocalvaria, Pulmonary hypoplasia
+serious: 1 patientsex: 2 drugs: GENTAMICIN SULFATE reactions: Dermatitis allergic, Device site dermatitis
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: SUCRALFATE reactions: Calcinosis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, RITUXIMAB reactions: Drug ineffective, Pneumonia cytomegaloviral
+serious: 1 patientsex: 2 drugs: ALBUTEROL, OMALIZUMAB, THEOPHYLLINE ANHYDROUS reactions: Asthma, Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: FENTANYL, GLYCOPYRROLATE, NITROUS OXIDE, ROCURONIUM BROMIDE, SEVOFLURANE, THIOPENTAL SODIUM reactions: Febrile convulsion
+serious: 1 patientsex: 1 drugs: CETIRIZINE HYDROCHLORIDE, EPINEPHRINE, MONTELUKAST SODIUM, PREDNISOLONE reactions: Abdominal pain lower, Blood pressure decreased, Cognitive disorder, Depressed level of consciousness, Dysarthria, Fatigue, Idiopathic mast cell activation syndrome, Loss of consciousness, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental disorder, Mental
+serious: 1 patientsex: 2 drugs: ALEDRINIC ACID, CEFUROXIME, FENTANYL, GLYCOPYRROLUM, KETAMINE, MIDAZOLAM HYDROCHLORIDE, ONDANSETRON, PROPOFOL, TRANEXAMIC ACID reactions: Anaphylactic reaction
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, PHENAZOLINUM reactions: Henoch-Schonlein purpura
+serious: 1 patientsex: 2 drugs: FERROUS SULFATE reactions: Atelectasis, Cough, Dyspnoea, Granuloma, Pulmonary consolidation, Pulmonary stenosis, Pulmonary fibrosis, Pulmonary consolidation
+serious: 1 patientsex: 2 drugs: ALGINIC ACID, CLEBOPIRADE, ESOMEPRAZOLE MAGNESIUM, SODIUM BICARBONATE reactions: Cognitive disorder, Drug ineffective, Fatigue, Sexual dysfunction
+serious: 1 patientsex: 2 drugs: NATALIZUMAB reactions: Granule cell neuropathy
+serious: 1 patientsex: 1 drugs: TERBINAFINE reactions: Pityriasis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Pseudocirrhosis
+serious: 1 patientsex: 1 drugs: CLOZAPINE, OLANZAPINE, QUETIAPINE, VENLAFAXINE HYDROCHLORIDE reactions: Constipation, Drug interaction, Dry heaving, Salivary hypersecretion, Salivary hypersecretion, Somnolence
+serious: 1 patientsex: 2 drugs: ALENDAZOLE, CISPLATIN, CYCLOPHOSPHAMIDE, CYTARABINE, METHYLCOBALAMIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug interaction, Hepatic enzyme increased, Hepatic enzyme increased, Hepatic function abnormal, Hepatic enzyme increased, Hepatic function abnormal, Hepatic enzyme increased, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepatic function abnormal, Hepati
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, DICLOFENAC, FILGRASTIM, VALSARTAN reactions: Dermatomyositis, Neutropenia
+serious: 1 patientsex: 1 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Cardiac tamponade
+serious: 1 patientsex: 1 drugs: IBRUTINIB reactions: COVID-19
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Cerebral haemorrhage
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, FOLIC ACID, METHYLPREDNISOLONE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: Plasma cell myeloma
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, THIOTEPA, VINCRISTINE reactions: Anaemia, Diarrhoea, Fatigue, Hypernatraemia, Neutropenia, Thrombocytopenia, Urinary incontinence
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CARBOPLATIN, ERLOTINIB, GEFITINIB, NIVOLUMAB, PEMETREXED reactions: Drug level increased, Interstitial lung disease
+serious: 1 patientsex: 1 drugs: CHOLECALCIFEROL, BEVACIZUMAB, HYDROCHLOROTHIAZIDE, LISINOPRIL reactions: Glomerulonephritis membranous
+serious: 1 patientsex: 1 drugs: CANAGLIFLOZIN, CIPROFLOXACIN, INSULIN GLARGINE, METFORMIN HYDROCHLORIDE, SITAGLIPTIN reactions: Fourniers gangrene
+serious: 1 patientsex: 1 drugs: CAPECITABINE, DOCETAXEL, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Paracoccidioidomycosis
+serious: 1 patientsex: 2 drugs: AMIODARONE HYDROCHLORIDE, CALCITRIOL, ERGOCALCIFEROL reactions: Hypocalcaemia, Hypomagnesaemia, Hypophosphataemia, Hypothyroidism
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CARVEDILOL, DIGOXIN, FUROSEMIDE, RIVAROXABAN, SPIRONOLACTONE, VALSARTAN reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: PREDNISOLONE reactions: Diabetes insipidus, Polyuria
+serious: 1 patientsex: 1 drugs: ILOPROST, SILDENAFIL reactions: Drug ineffective, Pneumonia
+serious: 1 patientsex: 2 drugs: LACOSAMIDE, LAMOTRIGINE, LEVETIRACETAM, VALPROIC ACID, TOPIRAMATE, ZONISAMIDE reactions: Drug ineffective, Hemianopia
+serious: 1 patientsex: 1 drugs: CASPOFUNGIN, HYDROXYCHLOROQUINE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, RITONAVIR reactions: Drug resistance, Septic shock
+serious: 1 patientsex: 2 drugs: PROPYLTHIOURACIL reactions: Foetal exposure during pregnancy, Hyperthyroidism, Goitre
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, FLUVASTATIN SODIUM, IRON, MYCOPHENOLIC ACID, PREDNISOLONE reactions: Abdominal tuberculosis
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, HUMAN IMMUNOGLOBULIN G, MEROPENEM, METRONIDAZOLE, RIFAZIMINE, VANCOMYCIN reactions: Clostridium difficile infection, Drug ineffective, Inflammation, Proctitis
+serious: 2 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL reactions: Upper respiratory tract infection
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DESAMETHAZONE reactions: Extravasation, Skin necrosis
+serious: 1 patientsex: 2 drugs: DIGOXIN, FUROSEMIDE, INSULIN NOS, NEBIVOLOL, RIVAROXABAN reactions: Spinal epidural haematoma
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, RITUXIMAB reactions: Dysphagia, Off label use, Pneumonia aspiration, Portal vein thrombosis, Peritonitis, Portal vein thrombosis, Weight decreased
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Anaemia, Cytomegalovirus enteritis, Small intestinal ulcer
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, PACLITAXEL, TOPOTECAN HYDROCHLORIDE reactions: Disease progression
+serious: 1 patientsex: 1 drugs: DIGOXIN, FUROSEMIDE, SPIRONOLACTONE reactions: Atrial fibrillation, Bradycardia, Delirium, Dyspnoea, Ejection murmur, Oedema peripheral, Pleural effusion, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion aspiration, Pulmonary oedema, Pulmonary congestion, Pleural effusion, Pulmonary congestion, Pulmonary congestion, Pleural effusion, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmonary oedema, Pulmonary congestion, Pulmon
+serious: 1 patientsex: 2 drugs: TRASTUZUMAB reactions: Loss of personal independence in daily activities, Vomiting
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, HEPARIN SODIUM, NITROGLYCERIN reactions: Quadriplegia, Spinal epidural haematoma
+serious: 1 patientsex: 1 drugs: GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Organising pneumonia
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, BISOPROLOL, CALCITRIOL, CIPROFLOXACIN, FUROSEMIDE, IRBESARTAN, HYDROXYCHLOROQUINE, MYCOPHENOLATE MOFETIL, SEVELAMER, VANCOMYCIN reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: LEVOFLOXACIN reactions: Toxic encephalopathy
+serious: 1 patientsex: 2 drugs: COLCHICINE reactions: Bicytopenia, Pancreatitis, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, TAMIFLUM reactions: Haemoptysis, Lemierres syndrome, Pneumonia
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE reactions: Cytomegalovirus infection, Endophthalmitis
+serious: 1 patientsex: 1 drugs: ATORVASTATIN reactions: Immune-mediated necrotising myopathy
+serious: 1 patientsex: 2 drugs: MEROPENEM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug interaction, Drug level below therapeutic, Seizure
+serious: 1 patientsex: 2 drugs: PACLITAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Ataxia, Eyelid ptosis, Neuropathy peripheral, Off label use, Rash haemorrhagic
+serious: 1 patientsex: 1 drugs: AMIKACIN, CYCLOSERINE, ETHAMBUTOL HYDROCHLORIDE, LINEZOLID, LEVOFLOXACIN, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, PROTHIONAMIDE reactions: Drug-induced liver injury, Hepatitis C, Nausea, Portal fibrosis
+serious: 1 patientsex: 1 drugs: RIBAVIRIN, SOFOSBUVIR reactions: Hepatitis C
+serious: 1 patientsex: 1 drugs: EPLERENONE, NEBIVOLOL, RAMIPRIL, SODIUM ZINC CYCLOSPORINE, VALSARTAN reactions: Drug ineffective, Hyperkalaemia, Renal impairment
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, PACLITAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Bundle branch block left, Cardiomyopathy
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS, VALGANCICLOVIR reactions: Epstein-Barr virus infection, Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 1 drugs: SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug eruption, Pruritus, Skin lesion
+serious: 1 patientsex: 1 drugs: GIMERACILOTERACILTEGAFUR, OTERACIL POTASSIUM reactions: Bone marrow failure, Hepatic function abnormal
+serious: 1 patientsex: 2 drugs: MORPHINE SULFATE reactions: Drug ineffective, Drug intolerance, Hypercholesterolaemia, Hypertension, Hypotension, Inappropriate schedule of drug administration, Pain, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity, Pain in extremity
+serious: 1 patientsex: 1 drugs: DARUNAVIR, DOLUTEGRAVIR, EMTRICITABINERILPIVIRINE HYDROCHLORIDE, RITONAVIR, TENOFOVIR DISOPROXIL FUMARATE reactions: Immune reconstitution inflammatory syndrome, Thyroid eye disease
+serious: 1 patientsex: 2 drugs: ANASTRAZOLE, FONDAPARINUX, TAMOXIFEN, TICLOPIDINE, WARFARIN reactions: Antiphospholipid syndrome
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOSPORINE, LIDOCAINE, METHYLPREDNISOLONE, MEXILETINE reactions: Cytomegalovirus infection, Colitis, Off label use, Tracheosis, Transaminases increased
+serious: 1 patientsex: 1 drugs: SILDENAFIL reactions: Enterococcal infection, Peritonitis
+serious: 1 patientsex: 2 drugs: METHYLPHENIDATE HYDROCHLORIDE reactions: Tongue biting
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHOTREXATE, RUXOLITINIB, VINCRISTINE reactions: Graft versus host disease
+serious: 1 patientsex: 1 drugs: FLECAINIDE, METOPROLOL TARTRATE reactions: Cardiac arrest, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DESFLURANE, PROPOFOL, REMIFENTANIL, ROCURONIUM BROMIDE reactions: Bradycardia, Trigeminal cardiac reflex
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Abdominal pain upper, Neuropathy peripheral, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, LOSARTAN reactions: Apis-dorsata sting, Ischaemia
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, ERLOTINIB, PEMETREXED reactions: Asthenia, Neuropathy peripheral, Nail toxicity
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, INFLIXIMAB, METHOTREXATE, PREDNISOLONE, TOCILIZUMAB reactions: Drug ineffective, Eosinophilia, Skin disorder
+serious: 1 patientsex: 2 drugs: TESTOSTERONE reactions: Breast cancer, Invasive ductal breast carcinoma
+serious: 1 patientsex: 1 drugs: ATEZOLIZUMAB reactions: Acute respiratory failure, Confusional state, Hypercalcaemia, Lethargy, Pneumonia, Respiratory failure
+serious: 1 patientsex: 1 drugs: ALBUTEROL, ENOXAPARIN, LEVETIRACETAM, ONDANSETRON, TRAMADOL reactions: Alanine aminotransferase increased, Aspartate aminotransferase increased, Drug interaction, Hepatic enzyme increased, Hepatitis A, Hepatitis B surface antibody positive, Hepatitis B surface antibody negative, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive, Hepatitis B surface antibody positive
+serious: 1 patientsex: 1 drugs: ASPIRIN, RAMIPRIL, SIMVASTATIN, SITAGLIPTIN reactions: Cholangiocarcinoma, Hypercalcaemia, Syncope
+serious: 1 patientsex: 2 drugs: BUSULFAN, FLUDARABINE PHOSPHATE, SIROLIMUS, TACROLIMUS reactions: Mycosis fungoides
+serious: 1 patientsex: 1 drugs: CARBIDOPALEVODOPA, PRAMIPEXOLE, QUETIAPINE, TRIHEXYPHENIDYL reactions: Catatonia
+serious: 1 patientsex: 2 drugs: ONDANSETRON reactions: Acute coronary syndrome, Drug hypersensitivity, Kounis syndrome
+serious: 1 patientsex: 1 drugs: ASPIRIN, CYPROHEPTADINE, HYDROXYZINE HYDROCHLORIDE, GUANFACINE reactions: Aggression, Drug ineffective, Headache, Suicidal ideation
+serious: 1 patientsex: 2 drugs: RANIBIZUMAB reactions: Retinal exudates, Subretinal fluid
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, DEXTROSE, ESMOLOL, OCTREOTIDE, PROPRANOLOL HYDROCHLORIDE reactions: Necrotising colitis, Rotavirus infection
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Cardio-respiratory collapse, Pneumothorax
+serious: 1 patientsex: 1 drugs: CITRATE reactions: Intestinal tuberculosis, Paradoxical drug reaction
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Epstein-Barr virus infection, Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, BUDESONIDE, INFLIXIMAB reactions: Crohns disease
+serious: 1 patientsex: 2 drugs: COLCHICINE, PREDNISONE, TRIAMCINOLONE reactions: Gastrointestinal disorder
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, CANDESARTAN, LENVATINIB reactions: Focal segmental glomerulosclerosis
+serious: 1 patientsex: 2 drugs: ALEMTUZUMAB, GLATIRAMER ACETATE, METHYLPREDNISOLONE, OCRELIZUMAB, PEGINTERFERON BETA-1A reactions: Exposure during pregnancy, Premature delivery
+serious: 1 patientsex: 2 drugs: ARSENIC TRIOXIDE, DEXAMETHASONE, IDARUBICIN, TRETINOIN reactions: Neutropenic sepsis, Respiratory failure
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB reactions: Aplasia pure red cell
+serious: 1 patientsex: 1 drugs: ATRIPLA, TENOFOVIR DISOPROXIL FUMARATE reactions: Fracture
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, METRONIDAZOLE reactions: Acute kidney injury, Crystal deposit nephropathy
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, TRASTUZUMAB reactions: Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug-induced liver injury, Encephalitis, Pneumonia necrotising, Pulmonary toxoplasmosis, Shock
+serious: 1 patientsex: 2 drugs: ISOPROTERENOL reactions: Arteriospasm coronary, Bradycardia, Hypotension, Syncope
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Blood creatinine increased, Glomerular filtration rate decreased
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE reactions: Drug ineffective, Lupus nephritis
+serious: 1 patientsex: 2 drugs: CEFAZOLIN, DESFLURANE, FENTANYL, REMIFENTANIL, ROCURONIUM BROMIDE, THIAMYLAL reactions: Kounis syndrome
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, PREDNISOLONE ACETATE reactions: Corneal abscess, Eye pain, Eye redness, Eye pain, Eye pain, Vision blurred
+serious: 1 patientsex: 2 drugs: CEFTAZIDIME, DOXYCYCLINE, MEROPENEM, MEROPENEMIMIPENEM reactions: Pancytopenia
+serious: 1 patientsex: 2 drugs: DISOPYRAMIDE, FLUNITRAZEPAM reactions: Cardiac arrest, Endocarditis, Intentional overdose, Sepsis, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Meningitis bacterial, Type I infection
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, FONDAPARINUX, LEVETIRACETAM, PALBOCICLIB, POTASSIUM reactions: Abdominal pain, Ascites, Coma, Confusional state, Disorientation, Headache, Hypomagnesaemia, Lethargy, Lethargy, Oedema peripheral, Posterior reversible encephalopathy syndrome, Vomiting
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, LINEZOLID, NAFCILLIN, TELAVINCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, THALIDOMIDE reactions: Acute myeloid leukaemia
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, CLOZAPINE, FLUPHENAZINE DECANOATE, OLANZAPINE, RISPERIDONE reactions: Dystonia, Tardive dyskinesia
+serious: 1 patientsex: 1 drugs: CLONIDINE, ENALAPRIL, NITROGLYCERIN, METOPROLOL, PRAZOSIN reactions: Hyperkalaemia, Neutropenia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, HUMAN IMMUNOGLOBULIN G, RITUXIMAB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: FLUOXETINE HYDROCHLORIDE, LITHIUM CARBONATE, OLANZAPINE, QUETIAPINE, VALPROIC ACID reactions: Drug ineffective, Drug interaction, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased,
+serious: 1 patientsex: 2 drugs: CLONIDINE, HYDRALAZINE HYDROCHLORIDE, METOPROLOL, PERINDOPRIL, ROSUVASTATIN, WARFARIN reactions: Anti-neutrophil cytoplasmic antibody positive vasculitis, Glomerulonephritis acute, Streptococcal bacteraemia
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CARVEDILOL, HYDROCHLOROTHIAZIDE, MIRTAZAPINE, LOSARTAN reactions: Hypercalcaemia, Urinary tract infection bacterial
+serious: 1 patientsex: 1 drugs: BENDAMUSTINE, CYCLOSPORINE, FLUDARABINE PHOSPHATE, MELPHALAN, METHOTREXATE, RITUXIMAB reactions: Clostridium difficile colitis, Febrile neutropenia, Myelodysplastic syndrome, Neutropenia
+serious: 1 patientsex: 1 drugs: ALLOPURINOL reactions: Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: ABACAVIR, ATAZANAVIR, DIDANOSINE, LAMIVUDINE, RITONAVIR, TRIAMCINOLONE reactions: Adrenal insufficiency, Drug interaction, Hypothalamic pituitary axis suppression, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: BISOPROLOL, DENOSUMAB, DOXAZOSIN MESYLATE, LANREOTIDE, TEMOZOLOMIDE reactions: Metastases to bone, Metastases to spine, Metastases to lung, Metastases to liver, Metastases to lung, Metastases to spine, Metastases to spine, Metastases to lung, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases to spine, Metastases
+serious: 2 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE, EXENATIDE reactions: Treatment noncompliance
+serious: 1 patientsex: 1 drugs: IBUPROFEN reactions: Bacteraemia, Endocarditis, Spinal epidural abscess
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOCETAXEL, GEMCITABINE, METHOTREXATE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCC
+serious: 1 patientsex: 1 drugs: DABIGATRAN ETEXILATE MESYLATE, NEBIVOLOL, SPIRONOLACTONE, VENLAFAXINE HYDROCHLORIDE reactions: Brain oedema, Cerebral haemorrhage, Subdural haematoma
+serious: 1 patientsex: 2 drugs: ASPIRIN, TICAGRELOR reactions: Haematochezia, Haemoptysis, Mucosal haemorrhage, Oedema, Oedema peripheral, Petechial haemorrhage, Peripheral ulceration, Peripheral haemorrhage, Peripheral ulceration, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral ulceration, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral ulceration, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral haemorrhage, Peripheral
+serious: 1 patientsex: 1 drugs: FLUNITRAZEPAM, GABAPENTIN, VALPROIC ACID reactions: Drug interaction, Gait disturbance
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Febrile neutropenia, Intestinal mucosal inflammation, Pneumonia
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, CLONAZEPAM, DONEPEZIL, GABAPENTIN, LOSARTAN, RIVASTIGMINE reactions: Anxiety, Confusional state, Fall, Fall prone, Fall, Fall, Confusional state, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Fall, Gait disturbance, Hallucination, visual, Loss of personal independence in daily activities, Mobility decreased, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status changes, Mental status
+serious: 1 patientsex: 2 drugs: EFAVIRENZ, EMTRICITABINE, NYSTATIN, TENOFOVIR DISOPROXIL FUMARATE reactions: Immune reconstitution inflammatory syndrome, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN reactions: Drug-induced liver injury, Procalcitonin increased, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: OCTREOTIDE ACETATE reactions: Cardiac failure, Drug ineffective
+serious: 1 patientsex: 2 drugs: MOXIFLOXACIN, PREDNISOLONE, TRIAMCINOLONE reactions: Cystoid macular oedema, Drug resistance
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM, OXCARBAZEPINE reactions: Status epilepticus
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, FENTANYL, HERBALS, TETRAHYDROXYCANNABINE, TRAMADOL reactions: Acute respiratory failure, Cardiogenic shock, End organ dysfunction syndrome, Hypotension, Multiple organ dysfunction syndrome, Toxic leukoencephalopathy
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Acute kidney injury, Diabetic ketoacidosis, Off label use, Type 1 diabetes mellitus
+serious: 1 patientsex: 1 drugs: FOLIC ACID, HYDROXYCHLOROQUINE, LEFLUNOMIDE, METHOTREXATE, SULFASALAZINE reactions: Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferase increased, Alanine aminotransferas
+serious: 1 patientsex: 1 drugs: ALFETANIL, GLYCOPYRROLATE, OXYGEN, SEVOFLURANE, THIOPENTAL SODIUM, VECURONIUM BROMIDE reactions: Tube complication
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Hypersensitivity pneumonitis
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, GINGKGO BILOBALA, OXYCODONE, TADALAFIL reactions: Drug interaction, Penile haematoma, Ecchymosis
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, METHOTREXATE reactions: Biliary giardiasis
+serious: 1 patientsex: 2 drugs: CLOFARABINE, POSACONAZOLE reactions: Multiple organ dysfunction syndrome, Sepsis
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Encephalopathy
+serious: 1 patientsex: 2 drugs: ENOXAPARIN, WARFARIN reactions: Nervous system disorder, Wound haematoma
+serious: 1 patientsex: 2 drugs: VALPROIC ACID reactions: Bradycardia, Off label use
+serious: 1 patientsex: 1 drugs: ABACAVIR, ATAZANAVIR, LAMIVUDINE, RITONAVIR reactions: Condition aggravated, Fall, Gait disturbance, Hyperreflexia, Leukoencephalopathy, Multiple injuries, Speech disorder, Therapeutic response decreased
+serious: 1 patientsex: 1 drugs: ALBUTEROL, IPRATROPIUM BROMIDE reactions: Condition aggravated, Pneumomediastinum, Subcutaneous emphysema
+serious: 2 patientsex: 2 drugs: BUPIVACAINE, FENTANYL, LIDOCAINE, MIDAZOLAM reactions: Foetal exposure during pregnancy
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, TRIAMCINOLONE ACETONIDE reactions: Blindness, Inflammation, Iridocyclitis, Ocular redness, Photophobia, Phacoantigenic uveitis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, METHOTREXATE, RITUXIMAB, VINCRISTINE reactions: Burkitts lymphoma
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, LEDIPASVIRSOFOSBUVIR reactions: Drug-induced liver injury, Hematemesis, Jaundice, Portal hypertensive gastropathy, Paracoccus infection, Septic shock
+serious: 1 patientsex: 1 drugs: HUMAN HUMAN GLOBULIN NOS reactions: Arthritis bacterial, Drug abuse, Mediastinal mass, Staphylococcal infection
+serious: 1 patientsex: 1 drugs: ASPIRIN, BICALUTAMIDE, DENOSUMAB, DEGARELIX, FLUTAMIDE, OLOPADACINE reactions: Hepatic function abnormal, Osteonecrosis jaw, Seizure
+serious: 1 patientsex: 1 drugs: CAPECITABINE, CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, OXALIPLATIN, PACLITAXEL, VINORELBINEVINORELBINE TARTRATE reactions: Drug ineffective, Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: HUMAN IMMUNOGLOBULIN G, THEOPHYLLINE ANHYDROUS, TERBUTALINE reactions: Acute kidney injury, Blood creatinine increased, Blood phosphorus increased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea increased, Blood urea decreased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DARATUMUMAB, LISINOPRIL, MYCOPHENOLATE MOFETIL, PREDNISONE, RITUXIMAB reactions: Bone marrow failure
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Diarrhoea, Palmar-plantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM, MANNITOL reactions: Hyperammonaemia, Seizure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Abdominal pain, Abdominal distension, Abdominal pain, Ascites, Blood bilirubin increased, Blood phosphorus increased, Blood leukocytosis, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood phosphorus increased, Blood urea increased, Blood
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENASPIRINCAFFEINE, IBUPROFEN, SUCRALFATE reactions: Duodenal ulcer, Gastric outlet obstruction, Peptic ulcer
+serious: 1 patientsex: 2 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Bone marrow failure, Gastrointestinal disorder
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB, PREDNISOLONE reactions: Neuropathy peripheral, Rash
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, DEXTROMETHORPHAN, PROPYLENE GLYCOL 3350 reactions: Acute kidney injury, Coagulopathy, Drug interaction, Hypotension, Lactic acidosis, Overdose, Polyuria, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: FENTANYL, MIDAZOLAM HYDROCHLORIDE, XYLOCAINE reactions: Chest wall rigidity
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, ENAPRIL reactions: Drug interaction
+serious: 1 patientsex: 2 drugs: ALEMTUZUMAB, CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, CISPLATIN, CYCLOSPORINE, FLUDARABINE PHOSPHATE, MYCOPHENOLATE MOFETIL, PREDNISONE, ROMIDEPSIN, VINCRISTINE reactions: Drug ineffective, Febrile state, Off label use, Pancytopenia, Renal failure, Splenomegaly
+serious: 1 patientsex: 2 drugs: IMIQUIMOD reactions: Hypomelanosis, Skin depigmentation
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, DOXYCYCLINE reactions: Fusobacterium infection, Lemierres syndrome
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Chylothorax
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Chorea, Dyskinesia, Hyperkinesia
+serious: 1 patientsex: 2 drugs: MEGESTROL ACETATE reactions: Abdominal pain, Nausea
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, BUDESONIDE, INFLIXIMAB, MESALAMINE reactions: Atypical haemolytic uraemic syndrome, Crohns disease, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Status epilepticus, Toxic neurotoxicity
+serious: 1 patientsex: 1 drugs: ASPIRIN, LISINOPRIL, PROPRANOLOL HYDROCHLORIDE reactions: Haematuria, IgA nephropathy, Proteinuria
+serious: 2 patientsex: 1 drugs: LACOSAMIDE, LEVETIRACETAM, VALPROIC ACID reactions: Suicidal ideation
+serious: 1 patientsex: 1 drugs: RISPERIDONE reactions: Posture abnormal
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Deep vein thrombosis
+serious: 1 patientsex: 1 drugs: BESILLOXACIN, PREDNISOLONE, TOBRAMYCIN, VALACYCLOVIR HYDROCHLORIDE reactions: Corneal infiltrates, Corneal oedema, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal infiltrates, Corneal in
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, GABAPENTIN, LISDEXAMFETAMINE, NORTRIPTYLINE reactions: Anorgasmia
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, AMPHETAMINE, DEXTROMETHORPHAN, DULOXETINE reactions: Seizure
+serious: 1 patientsex: 1 drugs: PHENIRAMINE MALEATE reactions: Acute kidney injury, Coma, Generalised tonic-clonic seizure, Multiple organ dysfunction syndrome, Overdose, Renal failure, Seizure, Tachycardia, Tachypnoea
+serious: 1 patientsex: 2 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, FLUOROURACIL reactions: Stevens-Johnson syndrome
+serious: 1 patientsex: 2 drugs: ASPIRIN, DULOXETINE, GLICLAZIDE, INSULIN GLARGINE, ROSUVASTATIN reactions: Hypertensive crisis
+serious: 1 patientsex: 1 drugs: AMISULPRIDE, ARIPIPRAZOLE, CLOZAPINE, FLUPENTHIXOL, HALOPERIDOL, RISPERIDONE reactions: Cardiac failure, Cardiomyopathy
+serious: 1 patientsex: 2 drugs: MESALAMINE, MESALAMINE MESYLATE, PREDNISOLONE reactions: Exposure during pregnancy, Premature delivery
+serious: 1 patientsex: 1 drugs: ALBUTEROL, ALBUTEROL SULFATE, AMINOPHYLLINE, BUDESONIDEFORMOTEROL, MAGNESIUM SULFATE, SEVOFLURANE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CISPLATIN reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: CAPECITABINE, DEXAMETHASONE, GEMCITABINEGEMCITABINE HYDROCHLORIDE, CHLORPHENIRAMINE MALEATE, GEMCITABINEGEMCITABINE HYDROCHLORIDE, ONDANSETRON, RANITIDINE, SODIUM CHLORIDE reactions: Anaemia, Peripheral neuropathy
+serious: 1 patientsex: 2 drugs: APIXABAN, DILTIAZEM, FUROSEMIDE, LEVETIRACETAM, METOLAZONE, METOPROLOL, ROMIPLOSTIM reactions: Pericardial haemorrhage, Pleural effusion
+serious: 1 patientsex: 2 drugs: VALPROIC ACID reactions: Intentional overdose, Seizure, Sinus tachycardia
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, IRBESARTAN, PERINDOPRIL reactions: Hypotension, Renal tubular disorder
+serious: 1 patientsex: 2 drugs: SERTRALINE HYDROCHLORIDE reactions: Confusional state, Hypoglycaemia, Presyncope
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, FLUCONAZOLE, LACTULOSE, NADOLOL, SPIRONOLACTONE, RIFAZIMINE reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Arteriospasm coronary
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Cardiac arrest, Drug ineffective
+serious: 1 patientsex: 2 drugs: VANCOMYCIN reactions: Seroma
+serious: 1 patientsex: 1 drugs: NINTEDANIB reactions: Hepatitis acute
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, FULVESTRAN ETEXILATE MESYLATE, PALBOCICLIB, SIMVASTATIN, TRAMADOL reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: ERTAPENEM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Acute kidney injury, Exposure during pregnancy, Pulmonary oedema, Sepsis
+serious: 1 patientsex: 2 drugs: CYTARABINE, IDARUBICIN, FLUDARABINE PHOSPHATE, RITUXIMAB, TACROLIMUS, RUXOLITINIB reactions: Bronchopulmonary aspergillosis, Drug ineffective, Off label use, Pulmonary alveolar proteinosis
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISONE, TEICOPLANIN reactions: Acute myocarditis, Anaemia, Cardiac arrest, Cardiogenic shock, Drug ineffective, Hypotension, Oliguria, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CAPTOPRIL, FUROSEMIDE, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, PREDNISONE, RITUXIMAB reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CASPOFUNGIN, FLUCONAZOLE reactions: Fungal infection, Device related infection
+serious: 1 patientsex: 1 drugs: CYTARABINE, DEXAMETHASONE, IDARUBICIN, METHOTREXATE, RITUXIMAB reactions: Alopecia, Asthenia, Bone pain, Dysphonia, Fatigue, Nausea, Neutropenia, Off label use, Pyrexia, Rash, Skin toxicity, Vomiting
+serious: 1 patientsex: 2 drugs: LIDOCAINE, METHYLPREDNISOLONE reactions: Arachnoiditis
+serious: 1 patientsex: 1 drugs: CISPLATIN, ETOPOSIDE, POTASSIUM CHLORIDE, NIELASTA reactions: Clostridium difficile colitis, Diarrhoea, Shock
+serious: 1 patientsex: 1 drugs: CISPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, PEMETREXED reactions: Disease progression
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, ASPARAGINASE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, FLUDARABINE PHOSPHATE, IDARUBICIN, PEGASPARGASE, VINCRISTINE reactions: Drug ineffective, Pulmonary infection
+serious: 1 patientsex: 2 drugs: CISPLATIN reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: APIXABAN reactions: Acute kidney injury, Renal haematoma, Renal pseudoaneurysm
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CARBOPLATIN, PACLITAXEL reactions: Disease progression, Skin eruption
+serious: 1 patientsex: 2 drugs: DICLOFENAC SODIUM reactions: Anaphylactic reaction
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, PREDNISONE, RIFAMPIN reactions: Disease progression, Drug ineffective
+serious: 1 patientsex: 1 drugs: AMIODARONE HYDROCHLORIDE, CARBIMAZOLE reactions: Acute pulmonary oedema, Drug ineffective, Hyperthyroidism
+serious: 1 patientsex: 2 drugs: OLAPARIB reactions: Anaemia
+serious: 1 patientsex: 2 drugs: APIXABAN, FLECAINIDE, METOPROLOL SUCCINATE reactions: Atrioventricular block first degree, Atrioventricular block second degree, Fatigue, Sinus bradycardia, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DOCETAXEL reactions: Cushings syndrome, Metastases to central nervous system, Non-small cell lung cancer, Respiratory failure
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, HYDROXYCHLOROQUINE, PEA, PREDNISONE, TOCILIZUMAB reactions: Device reaction, Hypertransaminasaemia, Off label use
+serious: 1 patientsex: 1 drugs: ERGOCALCIFEROL, OLAPARIB, TALAZOPARIB reactions: Anaemia, Fatigue, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ATENOLOL, ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN, TACROLIMUS reactions: Hepatic enzyme increased, Transaminases increased
+serious: 1 patientsex: 2 drugs: ANAKINRA, ASPIRIN, INFLIXIMAB, METHYLPREDNISOLONE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: FLUOXETINE HYDROCHLORIDE, DULOXETINE, METHIELDIME BLUE, ROPINIROLE reactions: Drug interaction, Serotonin syndrome
+serious: 1 patientsex: 1 drugs: FLUOROURACIL reactions: Cardiomyopathy
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, LEVOFLOXACIN reactions: Drug ineffective, Maternal exposure during pregnancy, Pyelonephritis, Renal infarct
+serious: 1 patientsex: 2 drugs: ABACAVIR, ASPIRIN, BUDESONIDE, CYCLOPHOSPHAMIDE, CYTARABINE, CYTARABINE HYDROCHLORIDE, HYDROCORTISONE, HYDROXYCHLOROQUINE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE HYDROCHLORIDE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, MET
+serious: 1 patientsex: 2 drugs: INSULIN ASPART, INSULIN DEGLUDEC, LANREOTIDE, VILDAGLIPTIN reactions: Hypoglycaemia
+serious: 1 patientsex: 2 drugs: ASPARAGINASE, DAUNORUBICIN, METHOTREXATE, VINCRISTINE reactions: Coagulopathy, Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, DEXAMETHASONE, METHYLPREDNISOLONE, OSELTAMIVIR, PREDNISONE, VORICONAZOLE reactions: Blood glucose increased, Cough, Dyspnoea, Hypoxia, Mucormycosis, Pyrexia, Weight decreased
+serious: 1 patientsex: 1 drugs: DACLATASVIR, RIBAVIRIN, SOFOSBUVIR reactions: Hepatitis C
+serious: 1 patientsex: 1 drugs: LITHIUM, RISPERIDONE reactions: Hyperprolactinaemia
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Histoplasmosis disseminated
+serious: 1 patientsex: 1 drugs: LEUPROLIDE ACETATE reactions: Injection site granuloma, Skin inflammation
+serious: 1 patientsex: 1 drugs: AVELUMAB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE, FILGRASTIM, LEVOFLOXACIN, VANCOMYCIN reactions: Immune reconstitution inflammatory syndrome
+serious: 1 patientsex: 1 drugs: CALCIUM GLUCONATE, INSULIN NOS, POTASSIUM CHLORIDE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, SODIUM BICARBONATE, VASOPRESSIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALECTINIB, BRIGATINIB, LORAZEPAM reactions: Radiation necrosis
+serious: 1 patientsex: 1 drugs: MERCAPTOPURINE, INFLIXIMAB reactions: Pneumocystis jirovecii pneumonia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DASATINIB, NILOTINIB, RITUXIMAB reactions: Anaemia, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ATORVASTATIN, CLONAZEPAM, LACOSAMIDE, LAMOTRIGINE, LEVETIRACETAM, PHENYTOIN, TRIAMTERENE, VALPROIC ACID reactions: Atrioventricular block first degree, Cardiac QRS complex prolonged, Conduction disorder, Electrocardiogram QRS complex prolonged, Electrocardiogram QRS complex prolonged, Electrocardiogram QRS complex prolonged, Electrocardiogram QRS complex prolonged, Left ventricular dysfunction, Ventricular tachycardia
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Cushings syndrome
+serious: 1 patientsex: 1 drugs: ADEFOVIR DIPIVOXIL, LAMIVUDINE, TENOFOVIR ALAFENAMIDE, VALSARTAN reactions: Drug ineffective, Drug resistance, Hepatocellular carcinoma
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE, PREDNISONE reactions: Acute myocardial infarction, Ischaemic cardiomyopathy, Pericarditis
+serious: 1 patientsex: 1 drugs: DOCETAXEL, PREDNISOLONE reactions: Febrile neutropenia, Pulmonary embolism
+serious: 1 patientsex: 1 drugs: ALBUTEROL, PREDNISONE reactions: Osteonecrosis
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, FLUCONAZOLE, VORICONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CAPECITABINE, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Skin reaction
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, CISATRACURIUM, FENTANYL, METHYLPREDNISOLONE, PROPOFOL reactions: Lactic acidosis
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, VANCOMYCIN reactions: Atypical infection, Drug ineffective, Osteomyelitis, Pneumonia pseudomonal, Septic shock
+serious: 1 patientsex: 1 drugs: DENOSUMAB, FLUOROURACIL, LEUCOVORIN, OXAPLATIN reactions: Decreased appetite, Diarrhoea
+serious: 1 patientsex: 2 drugs: HYDROXYUREA, THROMBOERECTIN reactions: Cellulitis, Eczema, Inflammatory syndrome, Palmar-plantar erythrodysaesthesia syndrome, Proteus infection, Skin atrophy, Skin ulcer, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: DICLOFENAC, LEVOTHYROXINE, SODIUM PIGOSULFATEMAGNESIUM CITRATE reactions: Hyponatraemic encephalopathy
+serious: 1 patientsex: 2 drugs: PREDNISONE reactions: Lung abscess
+serious: 1 patientsex: 1 drugs: ATROPINE, MIDAZOLAM HYDROCHLORIDE reactions: Anaphylactic shock
+serious: 1 patientsex: 2 drugs: ISONIAZID, PYRIDOXINE reactions: Death, Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: AMPICILLIN, LINEZOLID, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug level increased, Renal impairment
+serious: 1 patientsex: 2 drugs: CLARITHROMYCIN reactions: Generalised tonic-clonic seizure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOCETAXEL, DOXORUBICIN HYDROCHLORIDE reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: ATAZANAVIR, EVEROLIMUS, LAMIVUDINE, MYCOPHENOLIC ACID, PREDNISONE, RITONAVIR, ZIDOVUDINE reactions: Drug interaction, Oral ulcer, Perianal ulcer
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, PREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CANDESARTAN, IPILIMUMAB, NIVOLUMAB, RABEPROZOLE reactions: Enteritis, Pneumonitis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB reactions: Aspartate aminotransferase increased, Alanine aminotransferase increased, Hepatic function abnormal, Hepatic failure, Myodeopsia, Retinal haemorrhage, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: FIDAXOMICIN, METRONIDAZOLE, VANCOMYCIN reactions: Colitis microscopic
+serious: 1 patientsex: 2 drugs: BELIMUMAB, CYCLOSPORINE, ZOLEDRONIC ACID reactions: Eye pain, Ocular hypersensitivity, Ocular adduction defect, Posterior vitreous detachment, Periorbital swelling, Periorbital oedema, Periorbital ptosis, Retinal oedema, Visual field defect
+serious: 1 patientsex: 1 drugs: REGORAFENIB reactions: Hypertension, Hypoalbuminaemia, Proteinuria, Renal impairment
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, VINBLASTINE reactions: Cholestasis, Drug ineffective, Vanishing bile duct syndrome
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE reactions: Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: PREDNISONE reactions: Hepatitis B, Immunodeficiency, Off label use, Product use in unapproved indication, Tetanus
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Cytomegalovirus infection, Haematochezia, Pancytopenia, Pseudomonas infection
+serious: 1 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Acute kidney injury, Cobalt deficiency, Haemolytic anaemia, Haemolytic anaemia, Hypotension, Hypoxia, Menstrual bleeding, Pancytopenia, Schistocytosis, Sinus tachycardia
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, AZATHIOPRINE, INSULIN ASPART, INSULIN HUMAN, INSULIN HUMAN, INSULIN HUMAN, INSULIN PREDNISOLONE, NAFAMOSTAT reactions: Drug ineffective, Drug resistance, Drug intolerance, Drug resistance, Drug resistance, Drug resistance, Drug intolerance, Drug resistance, Drug resistance, Drug intolerance, Drug resistance, Drug intolerance, Drug resistance, Drug intolerance, Drug resistance, Drug intolerance, Drug resistance, Drug intolerance, Drug resistance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug intolerance, Drug into
+serious: 1 patientsex: 1 drugs: PROPOFOL reactions: Propofol infusion syndrome
+serious: 1 patientsex: 2 drugs: CHLOROQUINE, IBUPROFEN, PREDNISOLONE reactions: Raccoon eye
+serious: 1 patientsex: 2 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Acute kidney injury, Asthenia, Haemoptysis, Overdose
+serious: 1 patientsex: 2 drugs: DULOXETINE reactions: Impulse-control disorder, Suicidal ideation
+serious: 1 patientsex: 1 drugs: ABIRATERONE ACETATE, PREDNISONE reactions: Cardiac failure congestive, Fluid retention
+serious: 1 patientsex: 2 drugs: FOLIC ACID, METHOTREXATE reactions: Myelosuppression, Mucosal inflammation, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: ABACAVIR, EMTRICITABINETENOFOVIR DISOPROXIL FUMARATE, LAMIVUDINE, RILPIVIRINE reactions: Drug ineffective, Hepatic function abnormal
+serious: 1 patientsex: 2 drugs: AMPICILLIN, CEFTRIAXONE, RIVAROXABAN, PREDNISOLONE reactions: Aspergillus infection, Cardio-respiratory arrest, Drug ineffective, Haemoglobin decreased, Haemoglobin decreased, Haemoglobin decreased, Haemoglobin decreased, Intra-abdominal haematoma, Pericardial effusion, Pleural effusion, Pleural effusion, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic infarction, Splenic infarction, Splenic haematoma, Splenic infarction, Splenic infar
+serious: 1 patientsex: 2 drugs: BIPERIDEN HYDROCHLORIDE, CARBAMAZEPINE, CLOMIPRINE, CLOMIPRINE, CHLORPROMAZINE, INSULIN NOS, METFORMIN HYDROCHLORIDE, MIRTAZAPINE, VALPROIC ACID reactions: Circulatory collapse, Drug interaction, Lactic acidosis, Overdose, Suicide attempt
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, HYDROXYCHLOROQUINE, METHYLPREDNISOLONE reactions: Osteonecrosis
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Anaemia, Asthenia, Blood pressure increased, Blood urea increased, Blood urea increased, Blood urea increased, Blood pressure systolic increased, Blood urea increased, Blood urea increased, Blood pressure systolic decreased, Blood urea increased, Blood pressure systolic increased, Blood urea increased, Blood urea increased, Blood pressure systolic decreased, Blood urea increased, Blood pressure systolic decreased, Blood urea increased, Blood pressure systolic decreased, Blood pressure systolic increased, Blood pressure systolic decreased, Blood pressure systolic increased, Blood pressure systolic decreased, Blood pressure systolic increased, Blood pressure systolic decreased, Blood pressure systolic increased, Blood pressure systolic decreased, Blood pressure sys
+serious: 1 patientsex: 2 drugs: LOSARTAN, METHYLPREDNISOLONE, TIMOLOL MALEATE, PROTONIX reactions: Interstitial lung disease
+serious: 1 patientsex: 1 drugs: METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Immune reconstitution inflammatory syndrome, Pneumonia klebsiella
+serious: 1 patientsex: 2 drugs: REGADENOSONE, ESTROGENS reactions: Electrocardiogram ST segment depression
+serious: 1 patientsex: 2 drugs: PEMBROLIZUMAB, PAZOPANIB reactions: Infusion related reaction, Hypothyroidism, Hypertension
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CEFIXIME, MOXIFLOXACIN reactions: Enterocolitis bacterial, Staphylococcal infection
+serious: 2 patientsex: 2 drugs: HEPARIN SODIUM reactions: Foetal exposure during pregnancy
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Cerebral haemorrhage, Cerebral infarction
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN reactions: Hepatitis C, Metastases to spine, Metastases to lung, Metastases to spine, Pyrexia, Skin reaction
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, PREDNISONE, SULFASALAZINE reactions: Candida infection, Klebsiella infection, Polychondritis
+serious: 1 patientsex: 1 drugs: HYDROCORTISONE reactions: Drug ineffective, Periventricular leukomalacia
+serious: 1 patientsex: 1 drugs: CARBIMAZOLE, PREDNISONE, PYRIDOSTIGMINE reactions: Myasthenia gravis, Thyrotoxic crisis
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PEMETREXED reactions: Malignant neoplasm progression, Metastases to meninges
+serious: 1 patientsex: 2 drugs: SUNITINIB MALATE reactions: Ecchymosis, Leukopenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: CLOPIDOGREL BISULFATE, HEPARIN SODIUM, NITROUS OXIDE, WARFARIN reactions: Aortic thrombosis, Cerebral infarction, Drug abuse, Dysarthria, Eye movement disorder, Paralysis, Pulmonary embolism, Paralysis
+serious: 1 patientsex: 2 drugs: PREGABALIN reactions: Anaemia, Leukopenia, Pyrexia, White blood cell count decreased, White blood cell count increased, Pyrexia, Pyrexia, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count increased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell count decreased, White blood cell
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Diffuse large B-cell lymphoma
+serious: 1 patientsex: 1 drugs: DOCETAXEL, NINTEDANIB, RAMUCIRUMAB reactions: Anaemia, Decreased appetite, Gastric perforation, Pyrexia
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Ischaemic stroke
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN reactions: Hepatic encephalopathy, Overdose
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, GENTAMICIN, VANCOMYCIN reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, IRBESARTAN, LABETALOLLABETALOL HYDROCHLORIDE reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DEXAMETHASONE, FOLIC ACID, LEVOTHYROXINE, LORAZEPAM, OLANZAPINE, PANTOPRAZOLE SODIUM, ROSUVASTATIN, PROCHLORPERAZINE, PEMBROLIZUMAB, ROSUVASTATIN CALCIUM reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: SILDENAFIL reactions: Pulmonary arterial hypertension
+serious: 1 patientsex: 1 drugs: DOXORUBICIN HYDROCHLORIDE reactions: Disease progression
+serious: 1 patientsex: 1 drugs: CARFILZOMIB, DEXAMETHASONE, POMALIDOMIDE reactions: Burkholderia infection, Deep vein thrombosis, Meningitis bacterial, Pneumonia
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, AMOXICILLIN reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, CEFEPIME HYDROCHLORIDE, GENTAMICIN, MEROPENEM reactions: Brain death, Seizure
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, BISOPROLOL, FUROSEMIDE, GLYMEPIRIDE, HEPARIN SODIUM, HYDROCORTISONE, MITOTANE, PIOGLITAZONE, SPIRONOLACTONE, TELMISARTAN, WARFARIN POTASSIUM reactions: Hepatic infarction, Intestinal ischaemia
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, GLIPIZIDE, LEVOFLOXACIN, MOMETASONE, LOSARTAN, SPIRONOLACTONE, TORSEMIDE, WARFARIN reactions: Acute kidney injury, Hypoglycaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypoglycaemia, Hypokalaemia,
+serious: 1 patientsex: 1 drugs: MEROPENEM, VANCOMYCIN reactions: Cardiac tamponade, Pericardial effusion
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, PREDNISONE, WARFARIN reactions: Acute kidney injury, Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: EVEROLIMUS, LENVATINIB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: ALEMTUZUMAB, PREDNISONE, TACROLIMUS reactions: Autoimmune haemolytic anaemia, Enteritis, Fatigue, Jaundice, Leukopenia, Pancytopenia, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, WARFARIN reactions: Adenocarcinoma metastatic, Cardiac arrest, Coagulopathy, Pulmonary embolism, Pneumothorax, Respiratory disorder, Thrombotic phenotype
+serious: 1 patientsex: 2 drugs: CAPTOPRIL reactions: Chondrosarcoma, Intraductal breast carcinoma
+serious: 1 patientsex: 1 drugs: BUSULFAN, FLUDARABINE PHOSPHATE, METHOTREXATE, TACROLIMUS reactions: Cytopenia
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, FLUOROURACIL, IFOSFAMIDE, PEGINTERAL GRANULocyte Colony stimulating factor, VINCRISTINE reactions: Candida infection, Febrile neutropenia
+serious: 1 patientsex: 1 drugs: FINASTERIDE reactions: Anxiety, Depression
+serious: 1 patientsex: 2 drugs: LAMIVUDINE, NEVIRAPINE, STAVUDINE reactions: Immune reconstitution inflammatory syndrome, Pulmonary tuberculosis
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Disease recurrence
+serious: 1 patientsex: 2 drugs: CELECOXIB, FENTANYL, GABAPENTIN, MORPHINE, ROPIVACAINE HYDROCHLORIDE reactions: Vomiting
+serious: 1 patientsex: 1 drugs: CISPLATIN, ETOPOSIDE reactions: Anaemia, Appendicitis, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ASPIRIN, CARVEDILOL, CAPTOPRIL, CLOPIDOGREL BISULFATE, PANTOPRAZOLE SODIUM, WARFARIN reactions: Drug-induced liver injury
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISOLONE reactions: Hepatitis E, Epstein-Barr virus infection reactivation
+serious: 1 patientsex: 2 drugs: CRIZOTINIB reactions: Hepatitis fulminant
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Acute kidney injury, Cardiac arrest, Endocarditis fungal, Haemoperitoneum, Hypotension, Off label use, Sepsis, Pulmonary embolism, Transaminases increased
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Leishmaniasis
+serious: 1 patientsex: 2 drugs: BUSULFAN, CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, IDARUBICIN, MYCOPHENOLATE MOFETIL, POSACONAZOLE, URSODIOL, TACROLIMUS, VALGANCICLOVIR reactions: Adenovirus hepatitis, Candida infection, Candida sepsis, Candida infection, Diarrhoea, Hepatitis fulminant, Nausea, Pancytopenia, Sepsis, Vomiting
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, FLUDARABINE PHOSPHATE, GANCICLOVIR, MELPHALAN, METHOTREXATE, PREDNISONE, TACROLIMUS reactions: Enterococcal infection, Large intestine ileus
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Drug ineffective, Disseminated tuberculosis
+serious: 1 patientsex: 1 drugs: SILDENAFIL reactions: Drug interaction, Hepatic function abnormal, Overdose
+serious: 1 patientsex: 1 drugs: APIXABAN reactions: Hypersensitivity vasculitis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, GEMCITABINE reactions: Thrombotic microangiopathy
+serious: 1 patientsex: 2 drugs: CARVEDILOL, CINACALCET, MYCOPHENOLIC ACID, PREDNISOLONE, TACROLIMUS reactions: Interstitial lung disease, Pulmonary calcification
+serious: 1 patientsex: 1 drugs: WARFARIN reactions: Drug ineffective, Embolic stroke, International normalised ratio increased
+serious: 1 patientsex: 2 drugs: POLIDOCANOL reactions: Arterial embolism, Limb necrosis
+serious: 1 patientsex: 2 drugs: PATIROMER, SPIRONOLACTONE reactions: Hypomagnesaemia
+serious: 1 patientsex: 2 drugs: INFLIXIMAB reactions: Abdominal pain, Crohns disease, Diarrhoea, Diarrhoea
+serious: 1 patientsex: 2 drugs: BUPROPION, SERTRALINE HYDROCHLORIDE reactions: Reversible cerebral vasoconstriction syndrome
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CLORAMBUCIL, INSULIN NOS reactions: Hyperglycaemia, Pulmonary embolism
+serious: 1 patientsex: 2 drugs: CETIRELIX ACETATE, FLUOXETINE HYDROCHLORIDE, LEVOTHYROXINE, MEGESTROL ACETATE reactions: Vaginal dehiscence
+serious: 1 patientsex: 1 drugs: ALBUTEROL, CEFTRIAXONE, OXYGEN reactions: Drug hypersensitivity
+serious: 1 patientsex: 2 drugs: ALBUTEROL, CYCLOSPORINE, DEMEROXIDE, FLUTAMINE, HUMAN IMMUNOGLOBULIN G, ISONIAZID, RIBAVIRIN, SPIRONOLACTONE, TAMIFLUM, ZOSYN MEDROL reactions: Acute respiratory distress syndrome, Pneumonitis viral, Respiratory failure
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, LACOSAMIDE, LEVETIRACETAM, LISINOPRIL reactions: Atrioventricular block, Bundle branch block left, Electrocardiogram PR prolongation, Electrocardiogram QRS complex prolonged, Sinus bradycardia, Sinus pause, Sinus tachycardia
+serious: 1 patientsex: 2 drugs: CALCIUM, FLUOROURACIL, OXALIPLATIN reactions: Pulmonary hypertension, Respiratory failure
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CEFTAZIDIME, LINEZOLID, LACTULOSE reactions: Drug ineffective, Nephropathy toxic
+serious: 1 patientsex: 2 drugs: GEMCITABINE reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: CARVEDILOL, ECULIZUMAB reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 1 drugs: DOXORUBICIN HYDROCHLORIDE, IFOSFAMIDE reactions: Condition aggravated, Drug ineffective
+serious: 1 patientsex: 1 drugs: FENTANYL, KETAMINE, LEVETIRACETAM, MIDAZOLAM, PHENOBARBITAL, PROPOFOL, THIOPENTAL, VALPROIC ACID reactions: Drug ineffective, Status epilepticus
+serious: 1 patientsex: 2 drugs: LEVOTHYROXINE, PROPRANOLOL HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE reactions: Accidental overdose, Loss of consciousness, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: INSULIN NOS, MORPHINE reactions: Drug abuse, Splenic abscess
+serious: 1 patientsex: 2 drugs: MELPHALAN reactions: Disease progression, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFEPIME HYDROCHLORIDE, HYDROXYCHLOROQUINE, LEVOFLOXACIN, MYCOPHENOLIC ACID, PREDNISONE, SULFAMETHOXAZOLETRIMETHOPRIM, TACROLIMUS reactions: Acute kidney injury, Drug ineffective, Hyperkalaemia, Oliguria, Renal impairment
+serious: 1 patientsex: 2 drugs: CALCIUM CARBONATE, COBICISTAT, EMTRICITABINETENOFOVIR ALAFENAMIDE, FLUOXETINE HYDROCHLORIDE, LAMIVUDINE, PYRIMETHAMINE, RALTEGRAVIR reactions: Drug interaction, Drug resistance, Gene mutation, Neutropenia
+serious: 1 patientsex: 2 drugs: AFATINIB reactions: Decreased appetite, Hypertension, Rash acneiform, Paralysis
+serious: 1 patientsex: 1 drugs: ASPARAGINASE, CYCLOPHOSPHAMIDE, CYTARABINE, DAUNORUBICIN, ETOPOSIDE, METHOTREXATE, VINCRISTINE reactions: Nail pigmentation
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, METRONIDAZOLE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM reactions: Cardiac tamponade, Drug ineffective, Pericarditis, Septic shock
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM, PREGABALIN reactions: Drug intolerance, Hepatic encephalopathy
+serious: 1 patientsex: 2 drugs: DACTINOMYCIN, ETOPOSIDE, IFOSFAMIDE, VINCRISTINE reactions: Abdominal pain, Constipation, Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE reactions: Skin eruption
+serious: 1 patientsex: 2 drugs: LITHIUM reactions: Hypercalcaemia, Neuropsychiatric symptoms
+serious: 1 patientsex: 2 drugs: OMEPRAZOLE, SUNITINIB MALATE, TRASTUZUMAB reactions: Immune thrombocytopenic purpura
+serious: 1 patientsex: 2 drugs: HYDROCORTISONE reactions: Adrenal hyperplasia, Hypertension, Hyperpyrexia, Sepsis
+serious: 1 patientsex: 1 drugs: WARFARIN reactions: Acute kidney injury, Haematoma, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: BUPIVACAINE, ASPIRIN, ATORVASTATIN, CARVEDILOL, GLYMEPIRIDE, IMIPRAZOLE, IPRATROPIUM BROMIDE, MEPERIDINE, THIAZIDE, VALSARTAN reactions: Drug interaction, Serotonin syndrome
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, OMEPRAZOLE reactions: Acute kidney injury, Hypomagnesaemia, Torsade de pointes, Ventricular tachycardia
+serious: 1 patientsex: 1 drugs: GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Urinary retention, Urinary tract infection, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: ACYCLOVIR, AMLODIPINE BESYLATE, CLONAZEPAM, HYDROCHLOROTHIAZIDE, IRBESARTAN, FUROSEMIDE, HYDROCHLOROTHIAZIDE, METFORMIN HYDROCHLORIDE, MINOXIDE, PANTOPRAZOLE SODIUM, REPAGLINIDE, SPIRONOLACTONE reactions: Acute kidney injury, Drug interaction, Hypercalcaemia, Myoclonus, Renal impairment
+serious: 1 patientsex: 2 drugs: TOPIRAMATE reactions: Angle closure glaucoma, Pneumonia, Serous retinal detachment
+serious: 1 patientsex: 2 drugs: MAGNESIUM SULFATE reactions: Hypermagnesaemia, Nervous system disorder
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, TERBINAFINE, VORICONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOSPORINE, PREDNISOLONE reactions: Condition aggravated, Drug ineffective
+serious: 1 patientsex: 2 drugs: DARUNAVIRRITONAVIR, RALTEGRAVIR reactions: Acute kidney injury, Drug resistance, Hypokalaemia, Proteinuria, Renal toxicity
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, MESALAMINE, METHYLPREDNISOLONE, PREDNISONE reactions: Colitis ulcerative, Hepatic function abnormal, Herpes simplex, Hepatitis disseminated, Hepatitis cirrhosis, Herpes simplex colitis, Hepatitis bacterial, Hepatitis viragenic, Hepatitis bacterial, Hepatitis cirrhosis, Hepatitis viragenic, Hepatitis bacterial, Herpes simplex hepatitis, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis viragenic, Hepatitis
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, SILDENAFIL, TACROLIMUS, WARFARIN reactions: Drug interaction, Sporotrichosis
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE, METRONIDAZOLE, PREDNISONE reactions: Hepatitis herpes simplex
+serious: 1 patientsex: 2 drugs: LEVODPA, OXYCODONE, PREGABALIN, ROTIGOTINE reactions: Dizziness, Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, LORAZEPAM, METRONIDAZOLE, OLANZAPINE, VALPROIC ACID reactions: Condition aggravated, Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: CISPLATIN, DEXAMETHASONE, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, VINORELBINE TARTRATE reactions: Acute coronary syndrome, Coagulopathy, Pericardial effusion, Osteonecrosis
+serious: 1 patientsex: 1 drugs: DOXYCYCLINE, RIVAROXABAN reactions: Cerebral artery thrombosis, Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOCETAXEL, DOXORUBICIN, TRASTUZUMAB reactions: Acute respiratory distress syndrome
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, ECULIZUMAB, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, MET
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, CYCLOSPORINE, HYDROXYCHLOROQUINE, METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Acne, Dizziness, Staphylococcal infection
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, DOCETAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Proteinuria
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN, HYDROCORTISONE, METHOTREXATE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Abdominal compartment syndrome, Febrile neutropenia, Sepsis
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Autoimmune hepatitis
+serious: 1 patientsex: 2 drugs: ALPRAM, DICLOFENAC, FROVATRITAN, MILANACIPRAN, OXYCODONE, PREGABALIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, NIVOLUMAB, PREDNISONE reactions: Cataract nuclear, Conjunctival hyperaemia, Eye irritation, Iridocyclitis, Iridocyclitis granulomatous, Iridocyclitis, Iridocyclitis
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS, VALGANCICLOVIR reactions: Cytomegalovirus infection, Gastrointestinal toxicity
+serious: 1 patientsex: 2 drugs: IOHEXOL reactions: Generalised tonic-clonic seizure
+serious: 1 patientsex: 2 drugs: DULOXETINE, PREGABALIN, TRAMADOL reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOXORUBICIN, METHOTREXATE reactions: Status epilepticus
+serious: 1 patientsex: 2 drugs: IMATINIB MESYLATE reactions: Drug ineffective, Drug tolerance
+serious: 1 patientsex: 2 drugs: CEFUROXIME reactions: Arthritis reactive, Clostridium difficile colitis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOXORUBICIN, ETOPOSIDE, MITOTANE reactions: Febrile neutropenia, Pancreatic pseudocysts, Recurrent cancer
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Haemorrhagic transformation stroke
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID reactions: Blindness transient, Encephalopathy, Hypoglycaemia, Hyponatraemia, Rash maculo-papular
+serious: 1 patientsex: 1 drugs: LEDIPASVIRSOFOSBUVIR, ROMIPLOSTIM reactions: Asthenia, Encephalopathy, Leishmaniasis, Pyrexia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, METFORMIN HYDROCHLORIDE, RAMIPRIL, PREDNISOLONE, VINCRISTINE reactions: Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, METOPROLOL, OMEPRAZOLE reactions: Cholestasis, Drug ineffective, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Leiomyoma, OMEPRAZOLE reactions: Haemoglobin decreased, Renal impairment
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: EFAVIRENZ, LAMIVUDINE, TENOFOVIR DISOPROXIL FUMARATE reactions: Cytomegalovirus infection, Hydrocephalus, Meningoencephalitis cytomegalovirus, Pneumocystis jirovecii infection
+serious: 1 patientsex: 2 drugs: CISPLATIN, FLUOROURACIL reactions: Cardiogenic shock
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, DOCETAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AMIODARONE HYDROCHLORIDE reactions: Torsade de pointes
+serious: 1 patientsex: 1 drugs: HYDROXYUREA, PREDNISOLONE, RUXOLITINIB reactions: Disseminated tuberculosis
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE reactions: Aspergillus infection, Fusarium infection, Pulmonary aspergillosis, Sepsis
+serious: 1 patientsex: 1 drugs: ACYCLOVIR reactions: Acute kidney injury, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: IDELALISIB reactions: Dermatitis exfoliative, Off label use, Respiratory failure, Septic shock
+serious: 1 patientsex: 2 drugs: LACOSAMIDE, LEVETIRACETAM, PHENOBARBITAL, PHENYTOIN, VALPROIC ACID reactions: Bradycardia, Hypotension, Sinus node arrest, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: METHIMAZOLE, METOPROLOL reactions: Exposure during pregnancy, Pre-eclampsia, Respiratory distress syndrome
+serious: 1 patientsex: 1 drugs: AMIKACIN, AMOXICILLIN, HYDROCORTISONE reactions: Aspergillus infection, Exposure during pregnancy, Premature baby
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS, VALGANCICLOVIR reactions: Anaemia autoimmune, Epstein-Barr virus infection, Iron overload, Iron overload
+serious: 1 patientsex: 2 drugs: GENTAMICIN reactions: Dizziness, Ocular hyperaemia, Oscillation, Ocular dysfunction, Ocular dysfunction
+serious: 1 patientsex: 2 drugs: ALECTINIB, CODEIN PHOSPHATE, METHYLPREDNISOLONE, PREDNISOLONE reactions: Glomerulonephritis rapidly progressive, Pancreatitis
+serious: 1 patientsex: 2 drugs: CYTARABINE, FLUDARABINE PHOSPHATE, FILGRASTIM reactions: Febrile neutropenia, Urinary tract infection
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENCODEINE PHOSPHATE, CARBAMAZEPINE, GABAPENTIN reactions: Anxiety, Dizziness, Drug ineffective, Tremor
+serious: 1 patientsex: 1 drugs: TALATE reactions: Anaphylactic reaction, Drug ineffective, Gingival bleeding, Haematemesis, Melaena, Oral eruption, Treatment failure
+serious: 1 patientsex: 2 drugs: PALONOSETRON reactions: Vomiting
+serious: 1 patientsex: 2 drugs: METHOTREXATE, TOCILIZUMAB reactions: Pneumonia aspiration, Systemic inflammatory response syndrome
+serious: 1 patientsex: 2 drugs: CAPECITABINE, DASATINIB, PACLITAXEL, VINORELBINEVINORELBINE TARTRATE reactions: Diarrhoea, Neutropenia
+serious: 1 patientsex: 1 drugs: ADENOSINE, AMIODARONE, SOTALOL reactions: Drug hypersecretion
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, EPOPROSTENOL, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, SILDENAFIL, TACROLIMUS, WARFARIN reactions: Acute kidney injury, Shock haemorrhagic
+serious: 1 patientsex: 1 drugs: VALPROIC ACID reactions: Kaposis sarcoma
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CALCITRIOL, CINACALCET, FUROSEMIDE, HEPARIN SODIUM, LOSARTAN, METFORMIN HYDROCHLORIDE, ZOLEDRONIC ACID reactions: Hypercortisolism, Stress
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANATE POTASSIUM reactions: Agranulocytosis, Febrile neutropenia
+serious: 1 patientsex: 2 drugs: ACETAZOLAMIDE, LACOSAMIDE, LAMOTRIGINE, LEVETIRACETAM, TOPIRAMATE reactions: Drug ineffective, Myoclonus
+serious: 2 patientsex: 2 drugs: ACETAMINOPHEN, BUPIVACAINE HYDROCHLORIDE, EPINEPHRINE, IBUPROFEN, MORPHINE, OXYCODONE reactions: Respiratory arrest
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, MEROPENEM, MOXIFLOXACIN, PYRAZINAMIDE, RIFAMPIN, VORICONAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ASPIRIN, DIPYRIDAMOLE reactions: Shock, Splenic rupture
+serious: 1 patientsex: 2 drugs: EVEROLIMUS reactions: Off label use
+serious: 1 patientsex: 2 drugs: PEGINTERFERON ALFA-2B, RIBAVIRIN reactions: Retinopathy, Visual impairment
+serious: 1 patientsex: 1 drugs: TETRACAINE HYDROCHLORIDE reactions: Corneal decompensation, Punctate epithelial keratitis
+serious: 1 patientsex: 1 drugs: ABACAVIR, AMPHOTERICIN B, CYCLOPHOSPHAMIDE, ENFUVIR, LAMIVUDINE, MELPHALAN, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, MELPHALAN, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE SODIUM
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, INSULIN NOS, METOPROLOL, LISINOPRIL reactions: Immune-mediated necrotising myopathy
+serious: 1 patientsex: 1 drugs: DOXORUBICIN, METHOTREXATE, VINCRISTINE reactions: Pancytopenia, Neutropenia, Pneumonia, Pneumonia pulmonary
+serious: 1 patientsex: 2 drugs: BUPROPION HYDROCHLORIDE, TRAZODONE HYDROCHLORIDE reactions: Agitation, Agitation, Intentional overdose, Leukocytosis, Mental disorder, Overdose, Seizure
+serious: 1 patientsex: 2 drugs: LITHIUM reactions: Hypercalcaemia, Hyperparathyroidism
+serious: 1 patientsex: 1 drugs: BASILIXIMAB, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Anaemia, Anaemia cytomegaloviral, Anasarca, Anaemia, Anaemia recurrent, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia, Anaemia,
+serious: 1 patientsex: 1 drugs: DACLIZUMAB, NIVOLUMAB reactions: Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: EPINEPHRINE, LIDOCAINE, SIMVASTATIN reactions: Ocular oedema
+serious: 1 patientsex: 2 drugs: CISPLATIN, FLUOROURACIL reactions: Pancytopenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: OXALIPLATIN, PACLITAXEL, XELODA reactions: Fatigue, Hepatic function abnormal, Urinary tract infection fungal, Urinary tract infection bacterial
+serious: 1 patientsex: 1 drugs: METHAMPHETAMINE, NICOTINE, MIRTAZAPINE, RISPERIDONE reactions: Drug abuse, Head movement disorder
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, RIFAMPIN reactions: Fanconi syndrome acquired, Paralysis
+serious: 1 patientsex: 2 drugs: HEPARIN SODIUM, PHENYLEPHRINE HYDROCHLORIDE reactions: Abdominal compartment syndrome, Acute kidney injury, Haemoglobin decreased, Retroperitoneal haematoma
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: Pneumonia
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, VANCOMYCIN reactions: Drug ineffective, Pneumonia bacterial
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CARBOPLATIN, PACLITAXEL reactions: Fatigue, Neuropathy peripheral, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: TAMSULOSIN HYDROCHLORIDE reactions: Aortitis, Biliary dilatation, Biliary mass, Biliary tract disorder, Biliary tract disorder, Biliary mass, Biliary tract disorder, Biliary tract disorder, Biliary mass, Biliary tract disorder, Biliary tract disorder, Biliary mass, Biliary tract disorder, Biliary tract disorder, Biliary mass, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary tract disorder, Biliary
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, RITUXIMAB, TACROLIMUS reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ACETAMINOPHENOXYCODONE HYDROCHLORIDE, BUPROPION HYDROCHLORIDE reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: ADEFOVIR DIPIVOXIL, ENTECAVIR, LAMIVUDINE reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE reactions: Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: ADENOSINE, FLECAINIDE, PROTAFENONE reactions: Anaphylactic reaction, Hypotension
+serious: 1 patientsex: 2 drugs: ASPIRIN, RIVAROXABAN reactions: Carotid artery aneurysm
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, ETANERCEPT, CYCLOSPORINE, INFLIXIMAB, METHOTREXATE reactions: Drug ineffective, Drug resistance
+serious: 1 patientsex: 2 drugs: CLONAZEPAM, LEVETIRACETAM, VALPROIC ACID reactions: Drug ineffective, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, HYDROXYUREA reactions: Acute myeloid leukaemia, Drug resistance
+serious: 1 patientsex: 2 drugs: METHOTREXATE, METHYLPREDNISOLONE, PREDNISOLONE, VINNORELBINEVINNORELBINE TARTRATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: METHYLENE BLUE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, VANCOMYCIN reactions: Dermatomyositis, Stevens-Johnson syndrome
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, FENTANYL, HYDROMORPHONE, IBUPROFEN, MORPHINE SULFATE reactions: Duodenal ulcer haemorrhage
+serious: 1 patientsex: 1 drugs: BUSULFAN, FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS reactions: Bacteraemia, Alveolar haemorrhage, Pneumonia, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: AMIODARONE, EPINEPHRINE reactions: Drug ineffective, Haemoglobin decreased, Off label use, Ventricular fibrillation
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, CEFIXIME, CLINDAMYCIN reactions: Stevens-Johnson syndrome
+serious: 1 patientsex: 1 drugs: CABERGOLINE reactions: Pneumocephalus
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, VINBLASTINE reactions: Disease recurrence
+serious: 1 patientsex: 2 drugs: CYTARABINE, IDARUBICIN, TRETINOIN reactions: Haemorrhage
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, ETOPOSIDE, PREDNISOLONE, VINCRISTINE reactions: Leukopenia, Neutropenia
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID, AMPICILLIN SODIUMSULBACTAM SODIUM, CIPROFLOXACIN, COLISTIN, CIPROFLOXACIN HYDROCHLORIDE, GLIMEPIRIDE, IMIPENEM, INSULIN NOS, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS, VALGANCICLOVIR reactions: Acinetobacter infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection, Candida infection
+serious: 1 patientsex: 1 drugs: CYTARABINE, DAUNORUBICIN, FLUDARABINE PHOSPHATE, RASBURICASE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: IRINOTECAN reactions: Pancytopenia, Superior vena cava syndrome
+serious: 1 patientsex: 1 drugs: LOPERAMIDE HYDROCHLORIDE reactions: Acute kidney injury, Cardiac arrest, Drug abuse, Overdose, Ventricular tachycardia
+serious: 1 patientsex: 2 drugs: ASPIRIN, CARVEDILOL, EZETIMIBE, INSULIN DETEMIR, LINAGLIPTIN, LOSARTAN, ROSUVASTATIN CALCIUM, TICAGRELOR reactions: Acute kidney injury, Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 1 drugs: DICHENHYDRAMINE, HYDROCORTISONE, PREDNISONE, VANCOMYCIN reactions: Drug reaction, Emotional distress, Rash, Treatment noncompliance
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Gynaecomastia
+serious: 1 patientsex: 1 drugs: Activated charcoal, NICALIPINE, SODIUM POLYSTYRENE SULFONATE, SERTRALINE HYDROCHLORIDE, ZALEPLON reactions: Intentional overdose, Pneumatosis intestinalis, Suicide attempt
+serious: 1 patientsex: 2 drugs: EFAVIRENZ, EMTRICITABINE, FLUCONAZOLE, GANCICLOVIR, SULFAMETHOXAZOLETRIMETHOPRIM, TENOFOVIR reactions: Acute kidney injury, Drug interaction, Metabolic acidosis, Nephropathy toxic, Renal impairment
+serious: 1 patientsex: 1 drugs: AMIKACIN, CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, MEROPENEM, PREDNISONE reactions: Septic shock
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, FLUOROURACIL, METFORMIN HYDROCHLORIDE, TAMOXIFEN reactions: Hypertriglyceridaemia, Pancreatitis acute
+serious: 1 patientsex: 1 drugs: ANAKINRA, CANAKINUMAB, METHOTREXATE reactions: Drug intolerance, Rheumatoid arthritis
+serious: 1 patientsex: 1 drugs: EFAVIRENZ, ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, LEVOFLOXACIN, PYRAZINAMIDE, RIFAMPIN, SULFAMETHOXAZOLETRIMETHOPRIM, TENOFOVIR DISOPROXIL FUMARATE reactions: Acute kidney injury, Fungal infection, Pneumocystis jirovecii pneumonia
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CEFTRIAXONE, FLUCONAZOLE, METHOTREXATE, METOPROLOL, URSODIOL, SIROLIMUS, TACROLIMUS reactions: Abdominal pain upper, Bone pain, Duodenitis, Dysphagia, Oesophageal sphincter disorder, Muscle pain, Oesophageal pain, Oesophageal sphincter spasms, Oesophageal sphincter disorder, Oesophageal sphincter disorder, Oesophageal reflux disease, Oesophageal sphincter disorder, Oesophageal sphincter disorder, Oesophageal sphincter disorder, Oesophageal sphincter stenosis, Oesophageal reflux disease, Oesophageal sphincter stenosis, Oesophageal sphincter steno
+serious: 1 patientsex: 2 drugs: ALBUTEROL, ATROPINE, BUDESONIDE, FLUTICASONE PROPIONATESALMETEROL XINAFOATE, IPRATROPIUM BROMIDEOXYGEN, TIOTROPIUM BROMIDE reactions: Chest pain, Electrocardiogram ST segment elevation, Drug interaction
+serious: 1 patientsex: 2 drugs: CLOBAZAM, DEXAMETHASONE, LAMOTRIGINE, LEVETIRACETAM, METOCLOPRAMIDE, RANITIDINE, SEVOFLURANE, THIOPENTAL reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 1 drugs: VORICONAZOLE reactions: Aspergillus infection, Febrile neutropenia
+serious: 1 patientsex: 1 drugs: NIMESULIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, CYCLOPHOSPHAMIDE, DEXAMETHASONE reactions: Death
+serious: 1 patientsex: 1 drugs: CAPECITABINE, OXALIPLATIN reactions: Hepatic fibrosis, Hepatic sinusoidal obstruction syndrome, Peliosis, Sinusoidal obstruction
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ENALAPRIL, LAMIVUDINE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS, VALSARTAN reactions: Aortic stenosis, Vasculitis
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, CARBOPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: LIDOCAINE reactions: Anaphylactic reaction, Drug hypersensitivity
+serious: 1 patientsex: 2 drugs: LEVETIRACETAM reactions: Drug ineffective
+serious: 2 patientsex: 2 drugs: ASPIRIN reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, DEXAMETHASONE, METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CYTARABINE, DOXORUBICIN HYDROCHLORIDE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Acute lymphocytic leukaemia recurrent, Cardiac arrest, Febrile neutropenia, Respiratory arrest
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, METHOTREXATE, RITUXIMAB reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM, OMEPRAZOLE, LISINOPRIL, VALPROIC ACID reactions: Cerebral ischaemia, Cerebral interstitial nephritis
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, CYCLOSPORINE, INFLIXIMAB, METHOTREXATE, USTEKINUMAB reactions: Treatment failure
+serious: 1 patientsex: 1 drugs: FLUCONAZOLE, GENTAMICIN, IMIPENEM, TAZOCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Intestinal perforation
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN reactions: Acute kidney injury, Febrile neutropenia, Haemoglobin decreased, Leukopenia, Neutrophil count decreased, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, RITUXIMAB reactions: Pulmonary embolism
+serious: 1 patientsex: 1 drugs: HYDROCORTISONE reactions: Atrioventricular block complete, Ventricular fibrillation, Ventricular tachycardia
+serious: 1 patientsex: 2 drugs: CAPECITABINE, DACARBAZINE, MITOTANE reactions: Adrenocortical cancer metastatic, Malignant neoplasm progression
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM reactions: Drug intolerance, Epilepsy
+serious: 1 patientsex: 2 drugs: NITROFURANTOIN reactions: Chest pain, Dyspnoea, Pulmonary effusion
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CANAGLIFLOZIN, LISINOPRIL reactions: Candida infection, Febrile neutropenia, Klebsiella infection, Pyelonephritis, Sepsis
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, CLARITHROMYCIN, LEVOFLOXACIN, METHYLPREDNISOLONE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, RIFAMPIN reactions: Eosinophilic pneumonia acute, Pneumothorax, Respiratory distress
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, MEROPENEM, PYRAZINAMIDE, PYRIDOXINE, RIFAMPIN reactions: Bronchopulmonary aspergillosis, Drug interaction
+serious: 1 patientsex: 1 drugs: LEVETIRACETAM, TOPIRAMATE reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, CYTARABINE, DEXAMETHASONE, DOXORUBICIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Gastrointestinal haemorrhage, Shock haemorrhagic
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Diarrhoea, Palmar-plantar erythrodysaesthesia syndrome, Retinal vein occlusion
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Cholangitis
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, OLMESARTAN reactions: Autoimmune hepatitis, Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: CARBON MONOHYDRATE reactions: Dementia, Neuropsychiatric syndrome
+serious: 1 patientsex: 2 drugs: ABACAVIR, LAMIVUDINE reactions: Anaemia, Exposure during pregnancy, Hypersensitivity, Nausea, Vomiting
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, BISOPROLOL, HYDROCHLOROTHIAZIDE, INSULIN GLARGINE, LEVOTHYROXINE, METFORMIN HYDROCHLORIDE, NITROGLYCERIN, LOSARTAN reactions: Acute kidney injury, Chronic kidney disease, Drug interaction, Hypoxia, Renal tubular injury
+serious: 1 patientsex: 2 drugs: PREDNISONE, THALIDOMIDE reactions: Ascites, Hepatic failure, Hepatosplenomegaly, Oesophageal candidiasis, Septic shock
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, TEMOZOLOMIDE reactions: Disease progression, Hemiparesis, Leukopenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CASPOFUNGIN, INTERFERON GAMMA, ITRACONAZOLE, VORICONAZOLE reactions: Brain abscess, Headache, Visual impairment
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Hypersensitivity vasculitis
+serious: 1 patientsex: 2 drugs: LISINOPRIL, HYDROCHLOROTHIAZIDELISINOPRIL SULFATE, SPIRONOLACTONE reactions: Hypercalcaemia
+serious: 1 patientsex: 1 drugs: BETAMETHASONE ACETATE, BETAMETHASONE HYDROCHLORIDE, HYDROCORTISONE BUTYRATE, INSULIN NOS, MOMETASONE FUROATE, PSORALENULTRAVIRIDE PHOSPHATE, VOGLIBOSE reactions: Hypoglycaemia, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: INFLIXIMAB, METHOTREXATE reactions: Histoplasmosis disseminated, Ileal stenosis
+serious: 1 patientsex: 1 drugs: ATENOLOL, CITALOPRAM HYDROBROMIDE, CLONAZEPAM, CLOZAPINE, DIVALPROEX SODIUM, FLUOXETINE HYDROCHLORIDE, HALOPERIDOL, LITHIUM, OLANZAPINE, RISPERIDONE reactions: Drug ineffective, Microseizure, Speech disorder
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Recall phenomenon
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, OLMESARTAN MEDOXOMIL reactions: Acute kidney injury, Metabolic acidosis, Sprue-like enteropathy
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Disease progression, Fatigue, Arthralgia, Malignant neoplasm progression, Metastases to pelvis, Renal cell carcinoma, Right ventricular failure
+serious: 1 patientsex: 1 drugs: MIRTAZAPINE, SERTRALINE HYDROCHLORIDE reactions: Bradyarrhythmia, Hypotension, Overdose
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Diabetic ketoacidosis, Diabetes mellitus
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOXORUBICIN reactions: Off label use
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN, METRONIDAZOLE reactions: Bacteraemia, Drug resistance, Pyelonephritis
+serious: 1 patientsex: 2 drugs: DESVENLAFAXINE HYDROCHLORIDE, SUMITRIPTAN reactions: Acute myocardial infarction, Arteriospasm coronary, Electrocardiogram ST segment elevation
+serious: 1 patientsex: 2 drugs: ANASTROZOLE, CYCLOPHOSPHAMIDE, DOXORUBICIN, EXEMESTANE, FLUOROURACIL, PACLITAXEL, TEMOZOLOMIDE reactions: Febrile neutropenia, Diarrhoea, Fatigue, Metastases to lung, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metastases to mediastinum, Metastases to lymph nodes, Metasta
+serious: 2 patientsex: 2 drugs: DENOSUMAB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, TACROLIMUS reactions: Glomerulonephritis
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL reactions: Acute kidney injury, Crystal nephropathy
+serious: 1 patientsex: 1 drugs: METHYLPHENIDATE HYDROCHLORIDE, RISPERIDONE reactions: Dystonia
+serious: 1 patientsex: 2 drugs: CLARITHROMYCIN, METHOTREXATE reactions: Abortion spontaneous, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: METRONIDAZOLE, PAROMOMYCIN reactions: Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: DICLOPHENIRAMINE, FENTANYL, LEFLUNOMIDE, NORTRIPTYLINE reactions: Abdominal pain, Constipation, Drug interaction, Nausea, Myocardial infarction, Vomiting
+serious: 1 patientsex: 2 drugs: LISINOPRIL reactions: Angioedema
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, DOXYCYCLINE reactions: Choreoathetosis
+serious: 1 patientsex: 2 drugs: ASPIRIN, ATORVASTATIN, BISOPROLOL, ESCITALOPRAM OXALATE, ISOSORBIDE MONONITRATE, LIDOCAINE, LEVOBUPIVACAINE, TELMISARTAN reactions: Bradycardia, Hypotension, Loss of consciousness, Respiratory arrest, Somnolence
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, CYCLOSPORINE, HYDROXYCHLOROQUINE, METHOTREXATE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, RITUXIMAB reactions: Drug intolerance, Drug resistance, Leukopenia, Product use in unapproved indication, Rash
+serious: 1 patientsex: 1 drugs: ALBUTEROL, AZITHROMYCIN ANHYDROUS, CLONIDINE, BUSPIRONE HYDROCHLORIDE, CLONIDINE HYDROCHLORIDE, CITALOPRAM HYDROBROMIDE, GUANFACINE, LEVOCETIRIZINE, MONTELUKAST SODIUM, SERTRALINE HYDROCHLORIDE reactions: Anxiety, Drug ineffective, Drug intolerance, Irritability, Suicidal ideation
+serious: 1 patientsex: 1 drugs: ISOTRETINOIN reactions: Depression, Insomnia, Irritability, Sacroiliitis
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE reactions: Factor VIII increased
+serious: 1 patientsex: 1 drugs: COLISTIN, MEROPENEM reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: CAPECITABINE, OXALIPLATIN reactions: Bone marrow failure, Neurotoxicity, Vomiting
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CLINDAMYCIN, CIPROFLOXACIN, MEROPENEM, TIGECYCLINE reactions: Mycobacterium chelonae infection, Pneumonia
+serious: 1 patientsex: 2 drugs: PENICILLAMINE reactions: Anti-neutrophil cytoplasmic antibody positive vasculitis, Pulmonary-renal syndrome
+serious: 1 patientsex: 2 drugs: PEGINTERFERON ALFA-2A, RIBAVIRIN, TELAPREVIR reactions: Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, ASPIRIN, ATORVASTATIN, DOCUSATE, DILTIAZEM, LISINOPRIL, TRAMADOL reactions: Acute kidney injury, Nephrotic syndrome, Interstitial nephritis
+serious: 1 patientsex: 2 drugs: METHAMPHETAMINE, SUMATRIPTAN reactions: Drug abuse, Reversible cerebral vasoconstriction syndrome
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE reactions: Seizure
+serious: 1 patientsex: 2 drugs: DROSPIRENONEETHINYL ESTRADIOL reactions: Macular neuroretinopathy
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, RITUXIMAB, TACROLIMUS reactions: Retroperitoneal haematoma
+serious: 1 patientsex: 2 drugs: LENALIDOMIDE, RITUXIMAB reactions: COVID-19, Chest discomfort, Dizziness, Electrocardiogram QRS complex prolonged, Hypotension, Sinus bradycardia
+serious: 1 patientsex: 2 drugs: FENTANYL, NITROUS OXIDE, SEVOFLURANE, THIOPENTALIN reactions: Dystonia
+serious: 1 patientsex: 1 drugs: VALPROIC ACID reactions: Coma, Hyperammonaemia, Overdose, Respiratory acidosis
+serious: 1 patientsex: 2 drugs: ASPARAGINASE, CYCLOPHOSPHAMIDE, DOXORUBICIN, FILGRASTIM, PREDNISOLONE, VINCRISTINE reactions: Endometritis, Leukopenia, Neutropenia, Pseudomonas infection, Vaginal haemorrhage
+serious: 1 patientsex: 2 drugs: ASPIRIN reactions: Foetal death, Premature baby
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, CODEINE PHOSPHATE, IBUPROFEN reactions: Hereditary angioedema
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, DOXORUBICIN HYDROCHLORIDE, ETOPOSIDE, IRINOTECAN, NEDAPLATIN reactions: Drug ineffective, Neoplasm progression
+serious: 1 patientsex: 2 drugs: ERTAPENEM SODIUM reactions: Off label use
+serious: 1 patientsex: 1 drugs: PROPOFOL, REMIFENTANIL, ROCURONIUM BROMIDE reactions: Anaphylactic reaction
+serious: 1 patientsex: 1 drugs: AMOXICILLIN, ACTRAPID, INSULIN NOS, OMEPRAZOLE, TRAMADOL reactions: Hiccups
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, ETHAMBUTOL HYDROCHLORIDE, MOXIFLOXACIN, RIFAMPIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Neutropenic colitis
+serious: 1 patientsex: 2 drugs: TOPIRAMATE reactions: Angle closure glaucoma, Choroidal effusion, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, AMPHETAMINE, FLUOXETINE HYDROCHLORIDE, METHYLPHENIDATE HYDROCHLORIDE, QUETIAPINE, TOPIRAMATE reactions: Drug ineffective, Drug interaction
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, METFORMIN HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Acute kidney injury, Asthenia, Diabetes mellitus, Haematuria, Neutropenia, Pneumonia, Renal failure, Respiratory failure, Urinary tract infection
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, AZATHIOPRINE, FOLIC ACID, HYDRALAZINE HYDROCHLORIDE, HYDROXYUREA, DILTIAZEM, LEVOTHYROXINE, TACROLIMUS, TORSEMIDE reactions: Drug interaction, Pancytopenia
+serious: 1 patientsex: 1 drugs: EMPAGLIFLOZIN, GLIPHENURIDE, SITAGLIPTIN reactions: Fourniers gangrene
+serious: 1 patientsex: 1 drugs: HYDROCHLOROTHIAZIDEOLMESARTAN MEDOXOMIL, SIMVASTATIN reactions: Acute kidney injury, Dehydration, Diarrhoea, Weight decreased
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE, CLONAZEPAM, FLUOXETINE HYDROCHLORIDE, IMIPRINE, NABUMEONE, SIMVASTATIN, VALSARTAN reactions: Stress cardiomyopathy
+serious: 1 patientsex: 1 drugs: ESCITALOPRAM OXALATE reactions: Depression, Drug interaction, Hypothyroidism, Suicide attempt
+serious: 1 patientsex: 2 drugs: BASILIXIMAB, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Diabetic ketoacidosis, Transplant dysfunction
+serious: 1 patientsex: 2 drugs: ENALAPRIL, SIMVASTATIN reactions: Aortic occlusion, Drug ineffective, Diffuse dermal angiomatosis
+serious: 1 patientsex: 2 drugs: CEFURoxiME, LEVOFLOXACIN, PREDNISONE reactions: Intestinal failure, Multiple organ dysfunction syndrome
+serious: 1 patientsex: 2 drugs: LEFLUNOMIDE, MELOXICAM, METHOTREXATE, PREDNISONE reactions: Myelodysplastic syndrome, Rash, Skin haemorrhage
+serious: 1 patientsex: 1 drugs: DULOXETINE, DOXYCYCLINE, FENOFIBRATE, METFORMIN HYDROCHLORIDE, TRAZODONE HYDROCHLORIDE reactions: Abdominal pain, Diarrhoea, Leukocytosis, Pancreatitis acute, Tachycardia, Tachypnoea
+serious: 2 patientsex: 1 drugs: ASPIRIN, DIPYRIDAMOLE reactions: No adverse event
+serious: 1 patientsex: 1 drugs: NICARDIPINE, METOCLOPRAMIDE, PHENTOLAMINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BUSULFAN, CYCLOSPORINE reactions: Chiari malformation, Sleep apnoea syndrome
+serious: 1 patientsex: 2 drugs: OFLOXACIN, ONDANSETRON reactions: Delirium, Hallucination, visual
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, LEVETIRACETAM reactions: Glioblastoma multiforme
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, HYDROCORTISONE, NITRIC OXIDE reactions: Cardiomegaly, Hypertension
+serious: 1 patientsex: 2 drugs: COLISTIN, MEROPENEM, POLYMYXIN B, TIGECYCLINE reactions: Disseminated intravascular coagulation, Skin hyperpigmentation
+serious: 1 patientsex: 1 drugs: CIPEEMINE, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, TIGECYCLINE reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: CHLOROQUINE PHOSPHATE, CIPROFLOXACIN, HEPARIN SODIUM, MEROPENEM reactions: Arrhythmia, Multiple organ dysfunction syndrome, Torsade de pointes
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, SODIUM CHLORIDE reactions: Cushingoid, Diabetes mellitus, Hypoglycaemia, Proctatatis, Perianal abscess
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, ASPIRIN, NIVOLUMAB, PACLITAXEL reactions: Organising pneumonia
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, HEPARIN SODIUM, GABAPENTIN, HEPARIN SODIUM, SILVER SULFADIAZINE reactions: Retroperitoneal haematoma
+serious: 2 patientsex: 1 drugs: BUPIVACAINE HYDROCHLORIDE, CYCLOSPORINE, GABAPENTIN reactions: Off label use
+serious: 1 patientsex: 1 drugs: GLATIRAMER ACETATE reactions: Abortion spontaneous, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE reactions: Epstein-Barr virus infection, Trigeminal neuralgia
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE reactions: Acute myocardial infarction, Drug abuse
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Nephrotic syndrome, Urinary bladder oedema
+serious: 1 patientsex: 1 drugs: LEFLUNOMIDE, PREDNISONE reactions: Anaemia, Gastritis, Mucormycosis, Upper gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: TAMOXIFEN reactions: Lung injury
+serious: 1 patientsex: 2 drugs: ARGATROBAN, ASPIRIN, CLOPIDOGREL BISULFATE, IOPAMIDOL reactions: Contrast encephalopathy
+serious: 1 patientsex: 1 drugs: LEFLUNOMIDE, METHOTREXATE reactions: Lymphadenitis, Mycobacterium paraffinicum infection
+serious: 2 patientsex: 2 drugs: GLIMEPIRIDE, INSULIN NOS, METFORMIN HYDROCHLORIDE reactions: Hypoglycaemia
+serious: 1 patientsex: 1 drugs: EMPAGLIFLOZIN, GLIPIZIDE, LINAGLIPTIN, METFORMIN HYDROCHLORIDE reactions: Fourniers gangrene
+serious: 1 patientsex: 2 drugs: DOCETAXEL, PACLITAXEL, TRASTUZUMAB, ZOLEDRONIC ACID reactions: Cardiogenic shock, Drug hypersensitivity, Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: DOCETAXEL reactions: Febrile neutropenia
+serious: 1 patientsex: 1 drugs: DIGOXIN, INSULIN NOS, PREDNISOLONE, URSODIOL reactions: Chronic kidney disease, Protothecosis
+serious: 1 patientsex: 2 drugs: ASPIRIN, ENOXAPARIN, HYDROXYPROGESTERONE, METFORMIN HYDROCHLORIDE, ESTRADIOL reactions: Acute diabetic ketoacidosis, Hypertriglyceridaemia, Pancreatitis haemorrhagic
+serious: 1 patientsex: 1 drugs: CALCIUM FOLIC ACID, METHOTREXATE reactions: Death, Neurotoxicity
+serious: 1 patientsex: 1 drugs: ROSUVASTATIN CALCIUM reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, CISPLATIN, CYCLOPHOSPHAMIDE, DEXAMETHASONE, ETOPOSIDE reactions: Plasma cell myeloma
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, AZATHIOPRINE, BLEOMYCIN SULFATE, DACARBAZINE, DOXORUBICIN, GANCICLOVIR, LEFLUNOMIDE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, RITUXIMAB, VINBLASTINE reactions: Aortic valve disease, Aortic stenosis, Aortic valve disease reactivation, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease, Aortic valve disease
+serious: 1 patientsex: 1 drugs: ALEMTUZUMAB, CYCLOPHOSPHAMIDE, DEXAMETHASONE, FLUDARABINE PHOSPHATE, IBRUTINIB, POSACONAZOLE, SULFAMETHOXAZOLETRIMETHOPRIM, VALACYCLOVIR HYDROCHLORIDE reactions: Febrile neutropenia, Myositis
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID, CEFTRIAXONE, LEVOFLOXACIN, GENTAMICIN, TEICOPLANIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ALENDAZOLE, BISOCODIL, PRAZIQUANTEL reactions: Hepatitis
+serious: 1 patientsex: 2 drugs: ETANERCEPT, GOLIMUMAB reactions: Blindness, Depressed level of consciousness, Treatment noncompliance
+serious: 1 patientsex: 1 drugs: CEFDINIR, INSULIN NOS, PREDNISONE reactions: Diabetes mellitus, Nocardiosis, Pneumonia
+serious: 1 patientsex: 2 drugs: CISPLATIN reactions: Acute kidney injury, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: INTERFERON BETA-1B reactions: Thrombotic microangiopathy
+serious: 2 patientsex: 2 drugs: METFORMIN HYDROCHLORIDE reactions: Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: AZACITIDINE, EMTRICITABINE, TENOFOVIR DISOPROXIL FUMARATE reactions: Acute myeloid leukaemia, Cytopenia, Pseudomonas infection, Pyrexia
+serious: 1 patientsex: 2 drugs: DIAZOXIDE, LISINOPRIL reactions: Deep vein thrombosis, Swelling
+serious: 1 patientsex: 1 drugs: ASPIRIN, LANSOPRAZOLE, TICLOPIDINE reactions: Colitis microscopic
+serious: 1 patientsex: 1 drugs: MYCOPHENOLIC ACID, PREDNISONE, SIROLIMUS reactions: Epstein-Barr virus infection, Haemophagocytic lymphohistiocytosis
+serious: 2 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: Irritability
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE SODIUM, FAVIPIRAVIR reactions: Dysphagia, Pneumonia aspiration
+serious: 1 patientsex: 2 drugs: ORLISTAT reactions: Diarrhoea, Drug interaction, Urinary retention
+serious: 1 patientsex: 2 drugs: IMATINIB MESYLATE reactions: Acute hepatic failure, Chronic myeloid leukaemia
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, PACLITAXEL, ZOSYN TARTRATE reactions: Febrile neutropenia, Colitis bacterial, Febrile neutropenia, Pneumonia, Respiratory distress, Sepsis
+serious: 1 patientsex: 1 drugs: VISMODEGIB reactions: Decreased appetite, Muscle spasms, Rash pruritic
+serious: 1 patientsex: 1 drugs: BOSENTAN, HEPARIN SODIUM, MORPHINE, SILDENAFIL, VANCOMYCIN reactions: Drug ineffective, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, OMALIZUMAB, PREDNISONE, RIFLUMILAST, TEMOZOLOMIDE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: BACLOFEN, PREGABALIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ALFACALCIDOL, ASPIRIN, CALCIUM CARBONATE, CARVEDILOL, DILTIAZEM, ESOMEPRAZOLE MAGNESIUM, LINAGLIPTIN, NICORANDIL, PRASUGREL, ROSUVASTATIN, WARFARIN reactions: Drug-induced liver injury
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE, HYDROXYZINE HYDROCHLORIDE, FEXOFENADINE, PREDNISONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: DAUNORUBICIN, PEGASPARGASE, VINCRISTINE reactions: Acute kidney injury, Hypertension, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, VANCOMYCIN reactions: Clostridium difficile infection
+serious: 1 patientsex: 1 drugs: CASPOFUNGIN, CLINDAMYCIN, LINEZOLID, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, DOCETAXEL reactions: Skin reaction
+serious: 1 patientsex: 2 drugs: ASPIRIN, DIPYRIDAMOLE reactions: Gastrointestinal haemorrhage
+serious: 1 patientsex: 2 drugs: VALPROIC ACID reactions: Seizure
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, ASPIRIN, CYCLOPHOSPHAMIDE, CYTARABINE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Diabetic nephropathy, Focal segmental glomerulosclerosis, Interstitial nephritis
+serious: 1 patientsex: 1 drugs: DEFERASIROX, DEFEROXAMINE MESYLATE reactions: Headache, Skin reaction
+serious: 1 patientsex: 2 drugs: ATAZANAVIR, LAMIVUDINE, NEVIRAPINE, ZIDOVUDINE reactions: Treatment failure
+serious: 1 patientsex: 1 drugs: IBRUTINIB reactions: Haemorrhage intracranial
+serious: 1 patientsex: 2 drugs: DOXORUBICIN HYDROCHLORIDE reactions: Death, Neurotoxicity
+serious: 1 patientsex: 1 drugs: ALLOPURINOL reactions: Lichenoid keratosis
+serious: 1 patientsex: 1 drugs: NILOTINIB reactions: Drug withdrawal syndrome
+serious: 1 patientsex: 2 drugs: CEFTRIAXONE, LORAZEPAM, PANTOPRAZOLE SODIUM, VALPROIC ACID reactions: Resting tremor
+serious: 1 patientsex: 1 drugs: CISPLATIN, GIMERACILOTERACILTEGAFUR reactions: Malaise, Renal disorder
+serious: 1 patientsex: 1 drugs: HYDROXYUREA reactions: Anaemia, Pneumonia, Respiratory failure
+serious: 1 patientsex: 2 drugs: ALLOPURINOL, CARBAMAZEPINE, PHENYTOIN, VALPROIC ACID reactions: Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: NIVOLUMAB reactions: Autoimmune hepatitis, Hepatitis cholestatic
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, PREDNISOLONE reactions: Bone fracture, Insomnia
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM reactions: Heparin-induced thrombocytopenia
+serious: 1 patientsex: 2 drugs: CIPROFLOXACIN, PREDNISOLONE, RIFAMPIN reactions: Nausea, Rash
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALENDRONATE SODIUM, ASPIRIN, CALCIUM CARBONATEVITAMIN D NOS, HYDROXYCHLOROQUINE, NITROGLYCERIN, PREDNISONE reactions: Scleroderma renal crisis
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Caesarean section, Ectopic pregnancy
+serious: 1 patientsex: 2 drugs: BOSUTINIB, DASATINIB, IMATINIB MESYLATE, INTERFERON, PONATINIB reactions: Eczema, Pityriasis
+serious: 1 patientsex: 2 drugs: ATRACURIUM, DESFLURANE, ETOMIDATE, HEPARIN SODIUM, MIDAZOLAM HYDROCHLORIDE, NOREPINEPHRINE, PROTAMINE SULFATE, REMIFENTANIL, OXYGEN, NOREPINEPHRINE, REMIFENTANIL, MIDAZOLAM HYDROCHLORIDE, OXYGEN, REMIFENTANIL, NOREPINEPHRINE, MIDAZOLAM HYDROCHLORIDE, PROTAMINE SULFATE, REMIFENTANIL, PROTAMINE SULFATE, NOREPINEPHRINE, PROTAMINE SULFATE, REMIFENTANIL, NOREPINEPHRINE, PROTAMINE SULFATE, NOREPINEPHRINE, PROTAMINE SULFATE, REMIFENTANIL, NOREPINEPHRINE, PROTAMINE SULFATE, PROTAMINE SULFATE, REM
+serious: 1 patientsex: 1 drugs: ALPRAZOLAM, XANAX reactions: Acute kidney injury, Coma, Hyperkalaemia, Hypoxia, Leukocytosis, Metabolic acidosis, Overdose, Respiratory failure, Septic shock, Tachycardia, Vomiting
+serious: 1 patientsex: 2 drugs: CYTARABINE, FLUDARABINE PHOSPHATE, IDARUBICIN, GRANULOCYTE COLONY-STIMULATING FACTOR NOS, VORICONAZOLE reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: COLCHICINE reactions: Aspergillus infection, Cerebral haemorrhage
+serious: 1 patientsex: 2 drugs: COLCHICINE, DABIGATRAN ETEXILATE MESYLATE, PANTOPRAZOLE SODIUM reactions: Pericardial effusion, Pleural effusion
+serious: 1 patientsex: 2 drugs: ASPIRIN, HEPARIN SODIUM, METOPROLOL, POTASSIUM reactions: Ventricular tachycardia
+serious: 1 patientsex: 1 drugs: LEDIPASVIR, SIMEPREVIR, SOFOSBUVIR reactions: Hepatitis C
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, HYDROXYCHLOROQUINE reactions: Hepatic ischaemia, Hepatic artery thrombosis, Perivascular epithelioid cell tumour
+serious: 1 patientsex: 2 drugs: DENOSUMAB reactions: Hypercalcaemia, Hypercalciuria
+serious: 1 patientsex: 1 drugs: ABIRATERONE ACETATE, 223RaDICHLORIDE, PREDNISONE reactions: Disease progression
+serious: 1 patientsex: 2 drugs: FENTANYL, PROPOFOL, REMIFENTANIL, SEVOFLURANE reactions: Hypercapnia
+serious: 1 patientsex: 1 drugs: ASPIRIN, COBICISTAT, ELVITEGRAVIR, EMTRICITABINE, FOLIC ACID, FERROUS SULFATE, LISINOPRIL, METOPROLOL, MIRTAZAPINE, TENOFOVIR ALAFENAMIDE, SOFOSBUVIR reactions: Acute kidney injury, Hyperkalaemia, Renal tubular acidosis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PEMETREXED reactions: Toxicity to various agents
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Amenorrhoea, Premature menopause, Premature ovulation
+serious: 1 patientsex: 2 drugs: CHOLECALCIFEROL, METFORMIN HYDROCHLORIDE, URSODIOL reactions: Exposure during pregnancy, Sleep disorder, Somnolence
+serious: 1 patientsex: 2 drugs: CHLORPROMAZINE, OLANZAPINE reactions: Cataract nuclear, Corneal deposition, Corneal toxicity, Pupils unequal, Visual acuity reduced
+serious: 1 patientsex: 1 drugs: BRODOMIDOL, WARFARIN reactions: Haematuria, Intentional overdose, Prothrombin time prolonged, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, IMATINIB, METFORMIN HYDROCHLORIDE, SIMVASTATIN, SITAGLIPTIN reactions: Gastric polyp
+serious: 1 patientsex: 2 drugs: ESTROGENS, PROGESTERONE reactions: Breast cancer, Infiltrative ductal carcinoma, Thyroid cancer
+serious: 1 patientsex: 1 drugs: CEFAZOLIN, EPINEPHRINE, FENTANYL, MORPHINE, ROPIVACAINE HYDROCHLORIDE reactions: Atelectasis, Sleep disorder, Respiratory distress, Sedation disorder
+serious: 1 patientsex: 1 drugs: DIAZEPAM, PHENYTOIN, RANITIDINE reactions: Drug interaction, Hypersensitivity, Rash erythematous, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: CIPROFLOXACIN reactions: Hypersensitivity, Rash
+serious: 1 patientsex: 2 drugs: AMBRISENTAN, EPOPROSTENOL, SILDENAFIL reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: MELPHALAN, TOPOTECAN HYDROCHLORIDE reactions: Choroidal atrophy, Vitreous haemorrhage
+serious: 1 patientsex: 1 drugs: AMINOCAPROIC ACID, DEXAMETHASONE, MYCOPHENOLIC ACID, PREDNISONE, RITUXIMAB, ROMIPLOSTIM reactions: Drug ineffective, Thrombocytosis
+serious: 1 patientsex: 1 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: AMIODARONE, ATORVASTATIN, BISOPROLOL, WARFARIN reactions: Haemoptysis, Pulmonary toxicity
+serious: 1 patientsex: 1 drugs: FLUOROURACIL reactions: Accidental overdose, Cardiotoxicity, Neurotoxicity, Overdose, Suicide attempt
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, ATENOLOL, HYDROCHLOROTHIAZIDE, SPIRONOLACTONE reactions: Gynaecomastia
+serious: 1 patientsex: 2 drugs: TOPIRAMATE reactions: Angle closure glaucoma, Macular striae
+serious: 1 patientsex: 1 drugs: LOPERAMIDE HYDROCHLORIDE reactions: Brain injury, Brain injury
+serious: 1 patientsex: 1 drugs: INFLIXIMAB reactions: Abdominal pain, Abdominal discomfort, Diarrhoea, Ileus, Large intestine stenosis, Ocular ileus, Product use in unapproved indication, Small intestinal obstruction
+serious: 1 patientsex: 2 drugs: ANAKINRA, HYDROXYCHLOROQUINE reactions: Acute respiratory failure, Toxic myopathy
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, SULFAMETHOXAZOLETRIMETHOPRIM, TACROLIMUS, VALGANCICLOVIR reactions: Bladder cancer, BK virus infection, Diarrhoea, Nephropathy, Papillary urothelial carcinoma, Proteinuria, Weight decreased
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS, VALGANCICLOVIR reactions: Cytomegalovirus infection, Drug ineffective, Neutropenia, Pneumocystis jirovecii infection, Steroid diabetes
+serious: 1 patientsex: 1 drugs: BENZTROPINE, CHLORPROMAZINE, LEVOTHYROXINE, LORAZEPAM, LORAZEPAM HYDROCHLORIDE, LORAZEPAM HYDROCHLORIDE, LORAZEPAM HYDROCHLORIDE, LORAZEPAM, SPIRONOLACTONE, TAMSULOSIN reactions: Agranulocytosis, Drug interaction, Hypotension, Pyelonephritis, Septic shock
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CISPLATIN, CYCLOPHOSPHAMIDE, DOCETAXEL, EPIRUBICIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE, IFOSFAMIDE, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: TAMOXIFEN, PREDNISOLONE reactions: Deep vein thrombosis, Hepatic infarction, Malnutrition, Sepsis, Venous thrombosis
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CELECOXIB, FAMOTIDINE, IGURATIMOD, OLMESARTAN, PEMBROLIZUMAB, PREDNISOLONE reactions: Hepatosplenomegaly, Immune-mediated cytopenia, Off label use, Rash macular, White blood cell count decreased
+serious: 1 patientsex: 2 drugs: MANNITOL reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Nausea, Vomiting
+serious: 1 patientsex: 1 drugs: CYTARABINE, CHLORODEOXADENOSINE, PREDNISOLONE, VINBLASTINE reactions: Neutropenia, Pneumonia
+serious: 1 patientsex: 1 drugs: AMIKACIN, CILASTATIN SODIUMIMIPENEM, CLARITHROMYCIN, LINEZOLID, TIGECYCLINE reactions: Electrocardiogram QT prolonged
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, PREDNISONE reactions: Stevens-Johnson syndrome
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, DEXMEDETOMIDINE, OSELTAMIVIR, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Acute respiratory distress syndrome, Colitis ischaemic, Ileus, Megacolon
+serious: 1 patientsex: 1 drugs: ABIRATERONE ACETATE, BICALUTAMIDE, LEUPROLIDE ACETATE reactions: Breast cancer, Drug ineffective, Metastases to lymph nodes, Metastases to liver, Metastases to pancreas, Metastases to urinary bladder
+serious: 1 patientsex: 2 drugs: ENALAPRIL, FUROSEMIDE, METOPROLOL, MOFETIL MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Anaemia, Chronic graft dysfunction, Drug ineffective, Overdose, Pneumonitis, Urinary tract infection
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Cutaneous leishmaniasis
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, MYCOPHENOLATE MOFETIL reactions: Brain stem disorder, Meningitis viral, Pyrexia, Respiratory failure
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, PREDNISOLONE reactions: Osteoporosis, Femoral neck fracture
+serious: 1 patientsex: 2 drugs: CARVEDILOL, DULOXETINE HYDROCHLORIDE, DILTIAZEM, FUROSEMIDE, LISINOPRIL reactions: Abdominal pain, Drug level increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemoglobin decreased, Haemoglobin increased, Haemo
+serious: 1 patientsex: 1 drugs: HALOPERIDOL, LURASIDONE reactions: Agranulocytosis, Leukopenia, Neutropenia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, ROMIDEPSINE, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ERIBULIN MESYLATE reactions: Interstitial lung disease
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE reactions: Acute generalised exanthematous pustulosis
+serious: 1 patientsex: 2 drugs: FENTANYL, PROPOFOL, ROCURONIUM BROMIDE, SEVOFLURANE reactions: Airway collapse, Asthma, Wheezing
+serious: 1 patientsex: 2 drugs: MIRAFENIB reactions: Electrocardiogram QT prolonged, Electrocardiogram T wave amplitude increased, Ventricular extrasystoles
+serious: 1 patientsex: 1 drugs: AMOXICILLIN, ASPIRIN, DIPYRIDAMOLE, SUNITINIB MALATE reactions: Acute kidney injury, Haematuria, Hyponatraemia, Renal failure, Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: USTEKINUMAB reactions: Meningitis viral, Off label use
+serious: 1 patientsex: 2 drugs: OCTREOTIDE reactions: Disease progression
+serious: 1 patientsex: 2 drugs: NITROUS OXIDE reactions: Vitamin B12 deficiency, Myelopathy
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Ascites, Teratoma
+serious: 1 patientsex: 1 drugs: HUMAN IMMUNOGLOBULIN G, MYCOPHENOLIC ACID, PREDNISONE, PYRIDOSTIGMINE reactions: Histoplasmosis, Pulmonary cryptococcosis
+serious: 1 patientsex: 1 drugs: CYTARABINE, DEXRAZOXANE, ETOPOSIDE, MITOTANE reactions: Acute myeloid leukaemia recurrent, Cardiac failure congestive, Cardiomyopathy, Cardiotoxicity, Hypokinesia, Off label use, Sepsis
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISOLONE reactions: Chorioretinal atrophy, Eye abscess, Mycobacterium tuberculosis
+serious: 1 patientsex: 2 drugs: CISPLATIN, PACLITAXEL reactions: Acute kidney injury, Cardiac arrest, Disseminated intravascular coagulation, Oesophageal oedema, Septic shock
+serious: 1 patientsex: 1 drugs: CAPECITABINE, OXALIPLATIN reactions: Wound infection
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, FILGRASTIM, ETHIODIZED OIL, MELPHALAN, PREDNISONE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Multiple sclerosis relapse
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Arthritis, Inflammatory polyarthritis
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, PREDNISOLONE reactions: Drug ineffective, Exposure during pregnancy
+serious: 2 patientsex: 1 drugs: TOPIRAMATE reactions: Off label use
+serious: 1 patientsex: 2 drugs: MITOMYCIN reactions: Pterygium recurrence
+serious: 1 patientsex: 1 drugs: BISOPROLOL, DABIGATRAN ETEXILATE MESYLATE, FUROSEMIDE, RAMIPRIL reactions: Cardiac failure acute, Distal embolism, Embolism venous, Left ventricular dysfunction, Sinus tachycardia
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, RIVAROXABAN reactions: Atrial thrombosis, Drug ineffective
+serious: 1 patientsex: 1 drugs: FLUOROURACIL, RALTITREXED reactions: Coronary artery disease, Drug ineffective, Gastric adenocarcinoma, Hypercholesterolaemia, Malignant neoplasm progression, Metastases to liver, Metastases to intestine, Metastases to intestine, Metastases to liver, Metastases to intestine, Metastases to liver, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine, Metastases to intestine,
+serious: 1 patientsex: 1 drugs: IMIPENEM, OMEPRAZOLE, PREDNISONE, TINZAPARIN reactions: Drug ineffective, Haematuria, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: VINCRISTINE reactions: Peroneal neuropathy
+serious: 1 patientsex: 1 drugs: PREDNISOLONE, TACROLIMUS reactions: Dermatophytosis, Psoriasis, Psoriatic arthropathy
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, DABIGATRAN ETEXILATE MESYLATE, LEVETIRACETAM, METOPROLOL, TORSEMIDE reactions: Ischaemic stroke
+serious: 1 patientsex: 1 drugs: ATOVAQUONE, LINEZOLID, LEVOFLOXACIN, MEROPENEM, POSACONAZOLE, PREDNISONE, TACROLIMUS reactions: Nocardiosis, Paraesthesia
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL reactions: Pulmonary infection
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Pneumonia
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, ETOPOSIDE, MELPHALAN reactions: Aspergillus infection, Bacterial sepsis, Lactobacillus infection, Respiratory distress, Sepsis
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Bradycardia, Cardiac block complete, Myocarditis
+serious: 1 patientsex: 2 drugs: DOCETAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE, PAZOPANIB reactions: Acute respiratory distress syndrome, Pneumonitis
+serious: 1 patientsex: 1 drugs: KETAMINE HYDROCHLORIDE reactions: Drug abuse, Drug dependence, Drug-induced liver injury, Urinary bladder haemorrhage
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, DABIGATRAN ETEXILATE MESYLATE, METFORMIN HYDROCHLORIDE, METOPROLOL reactions: Atrial fibrillation, Bronchiectasis, Dyspnoea, Granulomatous inflammation, International normalised ratio increased, Lymphocytosis, Mycobacterium tuberculosis, Pleural effusion, Pulmonary lymphoma, Pulmonary thickening, Pulmonary lymphocytosis, Pulmonary granuloma, Pulmonary lymphocytosis, Pulmonary thrombosis, Pulmonary granuloma, Pulmonary lymphocytosis, Pulmonary thrombosis, Pulmonary granuloma, Pulmonary thrombosis, Pulmonary lymphocytosis, Pulmonary thrombosis, Pulmonary granuloma, Pulmonary thrombosis, Pulmonary lympho
+serious: 1 patientsex: 2 drugs: BROMAZEPAM, METHYLPREDNISOLONE, PREDNISONE, ROSUVASTATIN reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: MYCOPHENOLIC ACID, TACROLIMUS reactions: Acute kidney injury, Thrombotic microangiopathy
+serious: 1 patientsex: 1 drugs: ASPIRIN, METOPROLOL reactions: Tricuspid valve thrombosis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ERYTHROPOIETIN, PEGFILGRASTIM, PREDNISONE, VINCRISTINE reactions: Anaemia, Febrile neutropenia, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, DOLUTEGRAVIR, EMTRICITABINE, ITRACONAZOLE, TENOFOVIR DISOPROXIL FUMARATE reactions: Drug level below therapeutic, Histoplasmosis disseminated
+serious: 1 patientsex: 1 drugs: RIBAVIRIN reactions: Drug interaction
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISOLONE reactions: Drug eruption, Pneumocystis jirovecii infection
+serious: 1 patientsex: 1 drugs: AMPICILLIN, CEFTRIAXONE, MEROPENEM, VANCOMYCIN reactions: Rash maculo-papular
+serious: 1 patientsex: 2 drugs: ITRACONAZOLE, VORICONAZOLE reactions: Tendonitis
+serious: 1 patientsex: 1 drugs: AMIODARONE HYDROCHLORIDE, CARVEDILOL, FUROSEMIDE reactions: Hyperbilirubinaemia, Hyperthyroidism, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DABIGATRAN ETEXILATE MESYLATE reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 2 drugs: ENTECAVIR, SIROLIMUS reactions: Hepatitis B reactivation
+serious: 2 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CIPRO, CIPROFLOXACIN, CLARITHROMYCIN, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CLARITHROMYCIN, CIPROFLOXACIN, CLARITHROMYCIN, CIPROFLOXACIN, CLARITHROMYCIN, CIPROFLOXACIN, CLARITHROMYCIN HYDROCHLORIDE, CIPROFLOXACIN, CLARITHROMYCIN, CIPROFLOXACIN, CIPROFLOXACIN, CLARITHROMYCIN, CIPROFLOXACIN, CLARITHROMYCIN, CLARITHROMYCIN HYDROCHLORIDE, CLARITHROMYCIN SULFATE, CLARITHROMYCIN, CLARITHROMYCIN HYDROCHLORIDE, CLARITHROMYCIN SULF
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, ASPIRIN, METHYLDOPA, PREDNISOLONE reactions: COVID-19
+serious: 1 patientsex: 2 drugs: MEDROXYPROGESTERONE ACETATE reactions: Congenital prolonged QT syndrome type 2
+serious: 1 patientsex: 1 drugs: ASPIRIN, AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, DILTIAZEM, ENOXAPARIN, FUROSEMIDE, METFORMIN HYDROCHLORIDE, METOPROLOL, PREDNISONE, RIVAROXABAN, TOPOL XL reactions: Acute respiratory failure, Hyperglycaemia
+serious: 1 patientsex: 2 drugs: FOLIC ACID, LEFLUNOMIDE, METHOTREXATE, METAMIZOLE, PANTOPRAZOLE SODIUM, SIMVASTATIN reactions: Acute kidney injury, ADAMTS13 activity decreased, Hepatic cirrhosis, Hepatic failure, Hepatic toxicity, Hypokalaemia, Hypovolaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia, Hypokalaemia
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, AZATHIOPRINE, METHOTREXATE reactions: Drug ineffective, Maternal exposure during pregnancy
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE, SILDENAFIL reactions: Pseudocyst of pancreas
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, HEPARIN SODIUM, ISOSORBIDE MONONITRATE, METOPROLOL, NIFEDIPINE reactions: Gastrointestinal haemorrhage, Sepsis
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, FLUOROURACIL reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CELECOXIB, CISPLATIN, IRINOTECAN reactions: Leukopenia
+serious: 1 patientsex: 1 drugs: AMITRIPTYLINE, ATORVASTATIN, CLOPIDOGREL BISULFATE, DEXAMETHASONE, THIMAMINE, RAMIPRIL reactions: Acute kidney injury, Drug interaction, Metabolic acidosis, Multiple organ dysfunction syndrome, Tumour lysis syndrome
+serious: 1 patientsex: 1 drugs: METHOTREXATE, METHYLPREDNISOLONE reactions: Central nervous system lymphoma, Diffuse large B-cell lymphoma, Epstein-Barr virus infection, Gastritis ulcerative, Lymphoproliferative disorder, Nausea, Neutropenia, Speech disorder
+serious: 1 patientsex: 2 drugs: AMPICILLIN SODIUMSULBACTAM SODIUM, CLINDAMYCIN, LINEZOLID, MEROPENEM, PREDNISOLONE, TACROLIMUS reactions: Disseminated phaeohyphomycosis, Haemoptysis, Respiratory failure
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, ETRAVIRINE, RALTEGRAVIR, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Meningitis aseptic
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CARBOPLATIN, DOCETAXEL, ERLOTINIB reactions: Fluid retention syndrome
+serious: 1 patientsex: 2 drugs: BENZTROPINE, LITHIUM, OLANZAPINE, QUETIAPINE, RISPERIDONE, VALPROIC ACID reactions: Alopecia, Affect disorder, Dizziness, Gait disturbance, Gait disturbance, Obsessive-compulsive disorder, Obsessive-compulsive behaviour, Obsessive-compulsive disorder, Somnolence, Social withdrawal syndrome, Somnolence
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, FOLIC ACID, PEMETREXED reactions: Toxic epidermal necrolysis
+serious: 1 patientsex: 1 drugs: DENOSUMAB, METHOTREXATE, RADIUM RA-223 DICHLORIDE reactions: Prostatic specific antigen increased
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE, WARFARIN reactions: Drug intolerance, Gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CALCHICHEL, CIPROFLOXACIN, IBANDRONIC ACID, PREDNISOLONE reactions: Atypical fracture, Condition aggravated, Drug interaction, Tendonitis
+serious: 1 patientsex: 1 drugs: BOVIDONE-IODINE, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROFLOXACIN HYDROCHLORIDE, CIPROF
+serious: 1 patientsex: 1 drugs: CLONIDINE, FLUVOXAMINE, LINEZOLID, MIDAZOLAM HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE reactions: Serotonin syndrome
+serious: 1 patientsex: 1 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE reactions: COVID-19
+serious: 1 patientsex: 2 drugs: ALENDAZOLE, DECLARAZINE, IVERMECTIN reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: ATENOLOL, COLCHICINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISOLONE reactions: Gingival disorder, Periodontitis, Tooth loss
+serious: 1 patientsex: 1 drugs: POTASSIUM IODIDE reactions: Hypothyroidism
+serious: 1 patientsex: 2 drugs: CLINDAMYCIN, METRONIDAZOLE, METFORMIN HYDROCHLORIDE, VANCOMYCIN reactions: Clogged ears, Drug level increased, Ototoxicity
+serious: 1 patientsex: 1 drugs: ACETAZOLAMIDE, METHYLPREDNISOLONE, MOXIFLOXACIN, PREDNISOLONE ACETATE, PILOCARPINE reactions: Ocular hypertension
+serious: 1 patientsex: 1 drugs: BUSULFAN, FLUDARABINE PHOSPHATE, LEVOFLOXACIN, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: Mucormycosis
+serious: 1 patientsex: 1 drugs: MEROPENEM, TIGECYCLINE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CEFAZOLIN reactions: Acute kidney injury, Proteinuria, Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: MEROPENEM reactions: Clostridium difficile colitis, Intestinal stenosis
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, ETANERCEPT, LEFLUNOMIDE, METHOTREXATE, PREDNISONE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug ineffective, Whipples disease
+serious: 1 patientsex: 2 drugs: AMPICILLIN, BETAMETHASONE, AZITHROMYCIN ANHYDROUS, OXYTOCIN reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 2 drugs: DONEPEZIL, TAMSULOSIN reactions: Drug interaction
+serious: 1 patientsex: 1 drugs: TACROLIMUS reactions: Cholangitis, Synovial sarcoma
+serious: 1 patientsex: 1 drugs: APIXABAN, ATORVASTATIN, ENOXAPARIN, METOPROLOL reactions: Atrioventricular block, Haemorrhagic shock, Loss of consciousness, Supraventricular tachycardia
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, OXALIPLATIN reactions: Coronary artery vasoconstriction
+serious: 1 patientsex: 1 drugs: FENTANYL, ISOFLURANE, PROPOFOL, SUCCINYLCHOLINE reactions: Malignant hyperthermia
+serious: 1 patientsex: 1 drugs: ENTECAVIR, TENOFOVIR DISOPROXIL FUMARATE reactions: Hepatitis B reactivation
+serious: 1 patientsex: 1 drugs: ACYCLOVIR, CEFOTAXIME SODIUM, LEVOFLOXACIN, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, LENALIDOMIDE, PREDNISOLONE reactions: Disseminated intravascular coagulation, Septic shock
+serious: 1 patientsex: 2 drugs: ALPRAZOLAM, FLUOXETINE HYDROCHLORIDE, METHYLPHENIDATE HYDROCHLORIDE reactions: Aggression, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CYCLOPHOSPHAMIDE, EPIRUBICIN, FULVESTRANT, EVEROLIMUS, PACLITAXEL, TRIPTORELIN, TAMOXIFEN reactions: Breast cancer metastatic, Cough, Dyspnoea, Pleural effusion, Pleural infiltration, Pulmonary opacities, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pulmonary infiltration, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pleural effusion, Pulmonary infiltration, Pleural effusion, Pul
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Anaphylactic reaction
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, CYTARABINE, ETOPOSIDE, MERCAPTOPURINE, METHOTREXATE, NELARABINE, VINCRISTINE reactions: Acute graft versus host disease, Chronic graft versus host disease, Pneumonitis, Seizure, Serositis
+serious: 1 patientsex: 1 drugs: MITOMYCIN reactions: Urethro-cavernosal-spongiosal fistula
+serious: 1 patientsex: 1 drugs: VORICONAZOLE reactions: Cholestasis, Drug-induced liver injury, Hypertransaminasaemia
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Leukopenia
+serious: 1 patientsex: 1 drugs: ALCOHOL reactions: Atrial fibrillation, Nocardiosis, Pulmonary nodule, Right ventricular dysfunction, Pericardial effusion, Respiratory distress, Right ventricular dysfunction, Pericardial tamponade, Respiratory distress
+serious: 1 patientsex: 1 drugs: CALCIUM, CHOLECALCIFEROL, METHOTREXATE, OMEPRAZOLE, PREDNISOLONE reactions: Crohns disease
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Drug-induced psychotic disorder
+serious: 1 patientsex: 1 drugs: AMOXICILLIN, CLAVULANIC ACID, OLANZAPINE, TOPIRAMATE reactions: Graft site necrosis, Postoperative wound infection
+serious: 1 patientsex: 2 drugs: ATEZOLIZUMAB, PACLITAXEL reactions: COVID-19 pneumonia, Staphylococcal infection
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, CISPLATIN, DOCETAXEL reactions: Drug interaction, Inappropriate schedule of drug administration, Intentional product use issue, Product use issue
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM, ERTAPENEM SODIUM reactions: Off label use
+serious: 1 patientsex: 2 drugs: DOCETAXEL, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Anaemia, Decreased appetite, Diarrhoea, Fatigue, Neutropenia, Weight decreased, Vomiting
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Hepatic failure, Hepatitis B reactivation
+serious: 1 patientsex: 1 drugs: POLYMYXIN B reactions: Cognitive disorder, Neurotoxicity
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE, PHENOBARBITAL, RISPERIDONE, TIGABINE, VALPROIC ACID reactions: Drug interaction, Drug level decreased, Drug level increased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level increased, Drug level decreased, Drug level
+serious: 1 patientsex: 1 drugs: INFLIXIMAB, MESALAMINE reactions: Pulmonary embolism
+serious: 1 patientsex: 2 drugs: VENLAFAXINE HYDROCHLORIDE reactions: Galactorrhoea
+serious: 1 patientsex: 1 drugs: DALFAMPRIDINE, TYSABRINOL, TEMAZEPAM, VALACYCLOVIR HYDROCHLORIDE reactions: Epilepsy, Overdose, Seizure
+serious: 1 patientsex: 2 drugs: DAPSONE, BLINATUMOMAB, CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN, MERCAPTOPURINE, METHOTREXATE, PREDNISONE, VINCRISTINE reactions: Hyperkalaemia, Renal failure
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, LEVETIRACETAM, PIRACETAM, VALPROIC ACID reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: PIPERACILLIN SODIUMTAZOBACTAM SODIUM, TOBRAMYCIN reactions: Drug reaction with eosinophilia and systemic symptoms
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, IMATINIB MESYLATE reactions: Chloroma
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, AMLODIPINE BESYLATE, CANRENOIC ACID, FUROSEMIDE, IRBESARTAN, HYDROXYZINE HYDROCHLORIDE, PEGINTERFERON ALFA-2A, SPIRONOLACTONE, TOLVAPTAN reactions: Blood creatinine increased, Blood urea increased, Blood urea nitrogen increased, Blood urea increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen increased, Blood urea nitrogen increased, Blood urea nitrogen decreased, Blood urea nitrogen
+serious: 1 patientsex: 1 drugs: METRONIDAZOLE reactions: Hepatic abscess
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PACLITAXEL reactions: Infusion related reaction, Neuropathy peripheral, Transaminases increased
+serious: 1 patientsex: 2 drugs: BOSENTAN, SILDENAFIL reactions: Atrial septal defect, Pulmonary arterial hypertension
+serious: 1 patientsex: 1 drugs: BUDESONIDE, BUSULFAN, FLUDARABINE PHOSPHATE, TACROLIMUS reactions: Anaphylactic reaction, Drug hypersensitivity, Hypotension, Respiratory distress, Vomiting
+serious: 1 patientsex: 2 drugs: PANTOPRAZOLE SODIUM reactions: Anaphylactic reaction
+serious: 1 patientsex: 1 drugs: CISPLATIN, FLUOROURACIL reactions: Retinal detachment
+serious: 1 patientsex: 2 drugs: CLOBAZAM, CARBAMAZEPINE, DIAZEPAM, LAMOTRIGINE, LEVETIRACETAM, PERAMPANEL reactions: Drug ineffective, Epilepsy, Drug noncompliance, Drug level below therapeutic, Drug level below therapeutic, Epilepsy, Drug level below therapeutic, Drug level above therapeutic, Epilepsy, Drug level below therapeutic, Epilepsy, Epilepsy, Drug level below therapeutic, Epilepsy, Epilepsy, Drug level below therapeutic, Epilepsy, Epilepsy, Drug level below therapeutic, Epilepsy, Epilepsy, Epilepsy, Drug level below therapeutic, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epilepsy, Epile
+serious: 1 patientsex: 2 drugs: EVEROLIMUS, SUNITINIB MALATE reactions: Cardiac failure congestive, Mucosal inflammation, Palmar-plantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, CYTARABINE, ETOPOSIDE, METHOTREXATE, VINCRISTINE reactions: Cachexia, Depressive disorder, Malabsorption, Osteoporosis, Maternal exposure during pregnancy, Maternal exposure during pregnancy, Maternal exposure during pregnancy, Osteonecrosis, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature delivery, Premature labour, Premature labour, Premature delivery, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour, Premature labour,
+serious: 1 patientsex: 2 drugs: AMIODARONE HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: NITROUS OXIDE reactions: Vitamin B12 deficiency
+serious: 2 patientsex: 2 drugs: FLUNITRAZEPAM reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: AZATHIOPRINE, HUMAN IMMUNOGLOBULIN G, PREDNISOLONE, RITUXIMAB reactions: Generalised epilepsy, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: METHOTREXATE, PREDNISONE reactions: Pneumocystis jirovecii pneumonia
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, GEMCITABINEGEMCITABINE HYDROCHLORIDE reactions: Oesophageal fistula
+serious: 1 patientsex: 2 drugs: DENOSUMAB, LETROZOLE, ZOLEDRONIC ACID reactions: Atypical femur fracture, Joint pain, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: METHOTREXATE, METHYLPREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE, CLONAZEPAM, OLANZAPINE, PALIPERIDONE reactions: Akathisia, Drug ineffective, Extrapyramidal disorder, Self-mutilation
+serious: 1 patientsex: 2 drugs: CHLOROQUINE SULFATE reactions: Retinal degeneration, Retinal disorder, Retinal degeneration, Retinal depigmentation, Retinal degeneration, Retinal disorder, Retinal degeneration, Retinal disorder, Retinal degeneration, Retinal disorder, Retinal disorder, Retinal degeneration, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Retinal disorder, Re
+serious: 1 patientsex: 2 drugs: HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, SULFASALAZINE reactions: Drug reaction with eosinophilia and systemic symptoms, Epstein-Barr virus infection
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Hepatic enzyme increased
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Abdominal pain, Meningitis bacterial, Sepsis
+serious: 1 patientsex: 2 drugs: LEUPROLIDE ACETATE reactions: Off label use
+serious: 1 patientsex: 2 drugs: ASPIRIN, HEPARIN SODIUM reactions: Abortion spontaneous, Catastrophic antiphospholipid syndrome, Drug ineffective, Exposure during pregnancy, Renal failure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Diffuse large B-cell lymphoma, Pancytopenia
+serious: 1 patientsex: 2 drugs: AFATINIB, DEXAMETHASONE reactions: Diarrhoea, Rash
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, METOPROLOL, PENICILLIN G, VANCOMYCIN reactions: Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral infarction, Cerebral artery thrombosis, Cerebral infarction, Cerebral infarction, Cerebral infarction, Cerebral
+serious: 1 patientsex: 2 drugs: ALENDAZOLE, DAPHTHYLCARBAMAZEPINE, IVERMECTIN reactions: Abdominal pain, Dizziness, Fatigue, Headache, Nausea, Pyrexia, Rash
+serious: 1 patientsex: 1 drugs: LINEZOLID, CLINDAMYCIN, IMIPENEM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Ischaemic stroke
+serious: 1 patientsex: 1 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Carotid artery stenosis
+serious: 1 patientsex: 1 drugs: ETOMIDATE, OXYCODONE, REMIFENTANIL, ROCURONIUM BROMIDE, SEVOFLURANE reactions: Haemodynamic instability, Haemorrhage, Hypotension, Post procedural haemorrhage
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, MYCOPHENOLIC ACID reactions: Atypical mycobacterium infection, Actinic keratosis, Porokeratosis, Skin lesion
+serious: 1 patientsex: 1 drugs: DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, VINCRISTINE reactions: Bone marrow failure
+serious: 1 patientsex: 2 drugs: EPINEPHRINE, DOPAMINEDOPAMINE HYDROCHLORIDE, NOREPINEPHRINE, PROMETHAZINE HYDROCHLORIDE reactions: Acute myocardial infarction, Stress cardiomyopathy
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, DOCETAXEL, PACLITAXEL, NOREPINEPHRINE reactions: Intestinal perforation, Pyrexia, Subileus
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Bone marrow failure
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CEFTAZIDIME, CEFTRIAXONE, HYDROXYCHLOROQUINE, LEVOFED, MAGNESIUM, REMDESIVIR, TOCILIZUMAB reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: FUROSEMIDE, NITROPRUSSIDE reactions: Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, HYDROCORTISONE, METFORMIN HYDROCHLORIDE, TRIAMCINOLONE reactions: Adrenal insufficiency, Drug hypersensitivity, Hypertension
+serious: 1 patientsex: 2 drugs: DAPSONE, MYCOPHENOLATE MOFETIL, TACROLIMUS, VALGANCICLOVIR reactions: Chills, Disseminated tuberculosis, Thyroid tuberculosis
+serious: 1 patientsex: 1 drugs: VENLAFAXINE HYDROCHLORIDE reactions: Hypertensive encephalopathy
+serious: 1 patientsex: 2 drugs: AFATINIB reactions: Malignant neoplasm progression
+serious: 1 patientsex: 1 drugs: IPILIMUMAB, NIVOLUMAB, ZOLEDRONIC ACID reactions: Decreased appetite, Diarrhoea, Hepatic function abnormal, Nausea, Rash
+serious: 1 patientsex: 1 drugs: MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS reactions: Neoscytalidium infection
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE reactions: Acute kidney injury, Hypotension, Overdose, Sinus tachycardia
+serious: 1 patientsex: 1 drugs: ATORVASTATIN, CITALOPRAM HYDROBROMIDE, HYDROCHLOROTHIAZIDE, LORAZEPAM, METOPROLOL reactions: Haemorrhage intracranial, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: HYDROCORTISONE, KETOCONAZOLE, METYALPONE reactions: Adrenocorticotropic hormone syndrome, Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: METHIMAZOLE, METOPROLOL, PREDNISONE reactions: Gastrointestinal disorder, Hyperthyroidism
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, LETROZOLE, SORAFENIB reactions: Diarrhoea, Rash
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, CEFAZOLIN, ATEOSIBAN, BEMIPARINE, CEFAZOLIN, MAGNESIUM SULFATE reactions: Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE reactions: Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension, Adrenal hyperplasia, Adrenal hypertension,
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE reactions: Jarisch-Herxheimer reaction
+serious: 1 patientsex: 2 drugs: AMIKACIN, AMPHOTERICIN B, AMPHOTERICIN C, CEFUROXIME, IMIPENEM, MEROPENEM, PIPERACILLIN SODIUMTAZOBACTAM SODIUM, VANCOMYCIN reactions: Clostridium difficile infection, Drug resistance
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, BUDESONIDE, CYCLOPHOSPHAMIDE, HUMAN IMMUNOGLOBULIN G, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Drug withdrawal syndrome, Status epilepticus
+serious: 1 patientsex: 1 drugs: DEXAMETHASONE, INSULIN NOS, MANNITOL reactions: Drug ineffective, Growth hormone decreased
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Anorexia, Decreased appetite, Nausea, Renal impairment, Tuberculosis
+serious: 1 patientsex: 2 drugs: ASPIRIN, CLOPIDOGREL BISULFATE reactions: Accidental exposure to product, Headache, Ecchymosis, Multiple organ dysfunction syndrome, Retropharyngeal haematoma, Respiratory disorder
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, ETOPOSIDE, METHOTREXATE, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Blood 25-hydroxycholecalciferol decreased, Blood 25-hydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol decreased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol decreased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol decreased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol decreased, Blood 25-dihydroxycholecalciferol increased, Blood 25-dihydroxycholecalciferol decreased, Blood 25-dihydroxychol
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, PREDNISOLONE reactions: Intestinal obstruction, Necrotising fasciitis, Septic shock
+serious: 1 patientsex: 1 drugs: HALOPERIDOL DECANOATE, QUETIAPINE FUMARATE reactions: Acute kidney injury, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, CALCIUM, CILAZEPAIL, FOLIC ACID, ERYTHROPOIETIN, IRON, VALSARTAN reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE, METHOTREXATE, PREDNISOLONE reactions: Erythroderma
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, CEFAZOLIN, EPHEDRINE, FENTANYL, MORPHINE, PROPOFOL reactions: Confusional state
+serious: 1 patientsex: 2 drugs: BETAMETHASONE PHOSPHATE, TRIAMCINOLONE ACETONIDE reactions: Osteonecrosis
+serious: 1 patientsex: 1 drugs: AMIODARONE, APIXABAN reactions: Pneumonitis, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: LEVETIRACETAM, OLANZAPINE, TOPIRAMATE reactions: Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation, Agitation
+serious: 1 patientsex: 1 drugs: AMBRISENTAN, BOSENTAN, SIROLIMUS, TREPROSTINIL reactions: Hepatic function abnormal, Pulmonary oedema
+serious: 1 patientsex: 1 drugs: PREDNISOLONE reactions: Adrenal suppression, Immunosuppression, Necrotising fasciitis, Sepsis
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, EZETIMIBE, HYDROCHLOROTHIAZIDE, IRBESARTAN, RABEPRAZOLE, TAMOXIFEN reactions: Generalised tonic-clonic seizure, Hyponatraemia, Hypokalaemia
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOXORUBICIN, ETOPOSIDE, PACLITAXEL, PREDNISOLONE, WARFARIN reactions: Anaphylactic reaction, Deep vein thrombosis, Pericardial effusion, Pulmonary embolism, Pericardial haemorrhage
+serious: 1 patientsex: 2 drugs: BUPIVACAINE, CEFAZOLIN SODIUM, ENOXAPARIN SODIUM, FENTANYL, ISOFLURANE, LIDOCAINE, METOCLOPRAMIDE, RANITIDINE, OXYTOCIN, OXYGEN, OXYGEN TOCIN HYDROCHLORIDE, OXYTOCIN SULFATE, PROPOFOL reactions: Acute chest syndrome, Bradycardia, Hypotension, Maternal exposure during pregnancy, Vasoocclusive crisis
+serious: 1 patientsex: 1 drugs: ANAKINRA reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Hepatitis B reactivation
+serious: 1 patientsex: 1 drugs: ADEFOVIR, ENTECAVIR, LAMIVUDINE, PREDNISOLONE, TACROLIMUS reactions: Drug resistance, Hepatitis B
+serious: 1 patientsex: 1 drugs: ATORVASTATIN, METHYLPREDNISOLONE, PREDNISOLONE reactions: Drug ineffective, Myositis autoimmune
+serious: 1 patientsex: 2 drugs: IPILIMUMAB reactions: Meningoencephalomyelitis
+serious: 1 patientsex: 2 drugs: HYDROXYCHLOROQUINE reactions: Retinopathy
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, PACLITAXEL, TRASTUZUMAB reactions: Disease progression, Drug ineffective, Inflammation, Metastases to bone, Metastases to pelvis, Metastases to liver, Metastases to pelvis, Metastases to bone, Metastases to pelvis, Metastases to bone, Metastases to pelvis, Metastases to bone, Metastases to pelvis, Metastases to bone, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metastases to pelvis, Metasta
+serious: 1 patientsex: 1 drugs: CARBAMAZEPINE, CLOBAZAM, CLONAZEPAM, GLICLAZIDE, LACOSAMIDE, LEVETIRACETAM, LISINOPRIL, METFORMIN HYDROCHLORIDE, MIDAZOLAM HYDROCHLORIDE, PHENOBARBITAL, PHENYTOIN, PREDNISOLONE, TOPIRAMATE, VALPROIC ACID reactions: Drug ineffective, Rash
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE, CLOBAZAM, EPINEPHRINE, LEVETIRACETAM, PHENYTOIN, PROPOFOL, REMIFENTANIL, VALPROIC ACID reactions: Bradycardia, Bundle branch block right, Drug ineffective, Hypertriglyceridaemia, Lactic acidosis, Renal failure, Status epilepticus
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Stomatitis, Vomiting
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOCETAXEL, FLUOROURACIL reactions: Death, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: TERIPARATIDE reactions: Bone marrow failure, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: GENTAMICIN SULFATE reactions: Retinal haemorrhage, Retinal vein occlusion
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, MIDAZOLAM HYDROCHLORIDE reactions: Cerebral artery infarction, Epilepsy, Intracranial hypertension, Venous sinus thrombosis
+serious: 1 patientsex: 2 drugs: CISPLATIN, PACLITAXEL reactions: Haematotoxicity
+serious: 1 patientsex: 2 drugs: DROSPIRENONEETHINYL ESTRADIOLDROSPIRIN HYDROCHLORIDE, RIVAROXABAN reactions: Deep vein thrombosis, Pulmonary embolism
+serious: 1 patientsex: 1 drugs: CLOPIDOGREL BISULFATE reactions: Neovascular glaucoma
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE reactions: Acute hepatic failure, Hepatic enzyme increased, Hepatic failure acute, Hepatic enzyme increased, Hepatic failure acute, Hepatic enzyme increased, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepatic failure acute, Hepati
+serious: 1 patientsex: 1 drugs: METHOTREXATE, PREDNISONE, TOFACITINIB CITRATE reactions: Drug ineffective, Drug interaction, Hypertension, Nausea, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema peripheral, Oedema
+serious: 1 patientsex: 2 drugs: IOHEXOL reactions: Anaphylactic reaction
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, METHOTREXATE, PREDNISOLONE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: ALLOPURINOL, CALCITRIOL, CHOLECALCIFEROL, CYCLOSPORINE, DILTIAZEM, IRBESARTAN, METOPROLOL, PREDNISOLONE reactions: Anaemia, Gastritis, Metaplasia, Non-Hodgkins lymphoma, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: ACETATE SODIUM, ACETATE SODIUM BETA, ACETATE SODIUM CHLORIDE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM BETA, ACETATE SODIUM CHLORIDE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODIUM PHOSPHATE, ACETATE SODI
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CANDNEPOL, FLUCONAZOLE reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: FINASTERIDE reactions: Breast cancer
+serious: 1 patientsex: 2 drugs: BENZHEXOL, FLUOXETINE HYDROCHLORIDE, HALOPERIDOL, MONOPOLOL, SODIUM VALPROATE, TRANCODOL HYDROCHLORIDE reactions: Burning mouth syndrome
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, HYDROXYCHLOROQUINE, PANTOPRAZOLE SODIUM reactions: Acute kidney injury, Metabolic acidosis, Respiratory failure, Upper gastrointestinal perforation
+serious: 1 patientsex: 1 drugs: DIPHENHYDRAMINE, LAMIVUDINE, SODIUM CHLORIDE, TEMISIROLIMUS reactions: Hepatic enzyme increased, Hepatic failure, Hepatic enzyme increased, Hyponatraemia, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: AMIKACIN, MEROPENEM, SULFAMETHOXAZOLETRIMETHOPRIM, VANCOMYCIN reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: SULFAMETHOXAZOLETRIMETHOPRIM reactions: Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: NIVOLUMAB reactions: Vitiligo
+serious: 1 patientsex: 1 drugs: METHYLPREDNISOLONE, PREDNISOLONE reactions: Chorioretinopathy
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CYTARABINE, DAUNORUBICIN, TRETINOIN reactions: Hypokalaemia
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CAPECITABINE, OXALIPLATIN reactions: Toxic leukoencephalopathy
+serious: 1 patientsex: 1 drugs: METHYLPHENIDATE HYDROCHLORIDE reactions: Obsessive-compulsive disorder
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CALCIUM, DEXAMETHASONE, GABAPENTIN, LACTULOSE reactions: Bone marrow failure, Septic shock
+serious: 1 patientsex: 1 drugs: CASPOFUNGIN, CYCLOPHOSPHAMIDE, CYTARABINE, ETOPOSIDE, FLUDARABINE PHOSPHATE, INTERLEUKIN-2, MITOXANTRONE HYDROCHLORIDE, MICAFUNGIN SODIUM, SIROLIMUS, VORICONAZOLE reactions: Neutropenia
+serious: 1 patientsex: 2 drugs: METHOTREXATE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Drug interaction, Leukopenia, Mouth ulceration, Mucocutaneous ulceration, Renal failure, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: DACLATASVIR, PEGINTERFERON ALFA-2B, RIBAVIRIN, SOFOSBUVIR reactions: Ascites, Drug ineffective, Pleural effusion, Pericardial effusion
+serious: 1 patientsex: 1 drugs: ACETAMINOPHENOXYCODONE HYDROCHLORIDE, CELECOXIB, MELOXICAM, TRIAMCINOLONE reactions: Constipation, Drug dependence, Drug withdrawal syndrome, Somnolence
+serious: 1 patientsex: 2 drugs: ANASTROZOLE, LETROZOLE reactions: Hot flush
+serious: 1 patientsex: 2 drugs: PREDNISOLONE reactions: Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, INFLIXIMAB, PREDNISOLONE reactions: Amyloid goitre, Subacute thyroiditis
+serious: 1 patientsex: 1 drugs: CLOZAPINE reactions: Cardiac failure, Eosinophilia, Lung infiltration, Myocarditis, Pericardial fluid, Respiratory distress, Tricuspid valve incompetence
+serious: 1 patientsex: 2 drugs: COBICISTAT, ELVITEGRAVIR, EMTRICITABINE, TENOFOVIR ALAFENAMIDE reactions: Drug interaction, Iridocyclitis, Panuveitis, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: ALBUTEROL, PREDNISOLONE, SETRETEXIL, TIOTROPIUM BROMIDE reactions: Cardiac failure congestive, Drug level increased, Hypocalcaemia, Hypokalaemia, Hypomagnaesaemia, Hypothyroidism, Nausea, Sinus tachycardia, Vomiting
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, PREDNISOLONE reactions: Adrenal insufficiency, Immune-mediated hepatitis, Immune-mediated neoplasm progression, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immune-mediated thrombocytopenia, Immun
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN reactions: Acute kidney injury, Cardiac arrest, Overdose, Suicide attempt
+serious: 1 patientsex: 1 drugs: FINASTERIDE, TAMSULOSIN HYDROCHLORIDE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: AMETHOCAINE HYDROCHLORIDE, LIDOCAINE, POVIDONE-IODINE, RANIBIZUMAB reactions: Intraocular pressure increased
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, MYCOPHENOLIC ACID, TACROLIMUS reactions: Multiple organ dysfunction syndrome, Squamous skin carcinoma
+serious: 1 patientsex: 1 drugs: LEVODOPA, MAGNESIUM reactions: Drug ineffective, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, CLONAZEPAM, PROPRANOLOL HYDROCHLORIDE, VALBENAZINE reactions: Drug ineffective, Tardive dyskinesia
+serious: 1 patientsex: 2 drugs: CAPECITABINE, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Neuropathy peripheral
+serious: 1 patientsex: 1 drugs: LIDOCAINE reactions: Haematuria, Immune thrombocytopenic purpura, Petechiae, Rash erythematous
+serious: 1 patientsex: 2 drugs: SULFASALAZINE reactions: Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Testicular cancer
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CASPOFUNGIN, CYCLOSPORINE, FLUDARABINE PHOSPHATE, IMIPENEM, NOREPINEPHRINE, SULFAMETHOXAZOLETRIMETHOPRIM, VANCOMYCIN reactions: Candida infection, Drug ineffective, Pneumocystis jirovecii pneumonia, Septic shock
+serious: 1 patientsex: 2 drugs: GANCICLOVIR, LAMIVUDINE, NEVIRAPINE, STAVUDINE reactions: Immune-mediated uveitis
+serious: 1 patientsex: 1 drugs: INTERFERON BETA-1A, RIBAVIRIN reactions: Drug ineffective, Hepatitis B, Hepatitis C, Hepatitis D
+serious: 1 patientsex: 2 drugs: ANTITUXIMAB reactions: Botulism
+serious: 1 patientsex: 1 drugs: DAPTOMYCIN, MEROPENEM, VANCOMYCIN reactions: Febrile neutropenia, Pulmonary aspergillosis
+serious: 1 patientsex: 2 drugs: BISOCODYL, DOCUSATE SODIUMSENNOSIDES A AND B, DEXAMETHASONE, DOXORUBICIN, FLUCONAZOLE, IFOSFAMIDE, LOSARTAN, METOCLOPRAMIDE, NIFEDIPINE, OXYCODONE, PAROXETINE, MESNA, OXYCODONE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE, MESNA HYDROCHLORIDE, OXYCODONE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE, THIMAMINE, ONDANSETRON reactions: Drug interaction, Serotonin syndrome
+serious: 1 patientsex: 2 drugs: ATORVASTATIN CALCIUM, CINNARIZINE, FENOFIBRATE reactions: Drug intolerance, Memory impairment, Muscle spasms, Vertigo
+serious: 1 patientsex: 1 drugs: ACETAMINOPHEN, LEVOFLOXACIN reactions: Acute kidney injury, Crystal nephropathy
+serious: 1 patientsex: 2 drugs: ATORVASTATIN CALCIUM, METHYLPREDNISOLONE, NIFEDIPINE reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CAPECITABINE, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN, PANITUMUMAB reactions: General physical health deterioration, Jaundice
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, LAMOTRIGINE, RITUXIMAB reactions: Bile duct stenosis, Bile duct dilatation, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct dilatation, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct stenosis, Bile duct steno
+serious: 1 patientsex: 2 drugs: AFATINIB reactions: Decreased appetite, Nausea, Stomatitis
+serious: 1 patientsex: 1 drugs: METHOTREXATE, PREDNISOLONE reactions: Pulmonary mycosis
+serious: 1 patientsex: 1 drugs: METHOTREXATE reactions: Acute kidney injury, Hypotension
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, OMEPRAZOLE reactions: Hypomagnesaemia
+serious: 1 patientsex: 1 drugs: EFAVIRENZ, LAMIVUDINE, ZIDOVUDINE reactions: Buruli ulcer, Drug interaction, Paradoxical drug reaction
+serious: 1 patientsex: 1 drugs: CYTARABINE, METHOTREXATE, PREDNISOLONE reactions: Death, Neurotoxicity
+serious: 1 patientsex: 1 drugs: ALBUTEROL, CLONAZEPAM, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CLONAZEPAM HYDROCHLORIDE, CL
+serious: 1 patientsex: 1 drugs: AZACITIDINE, CETUXIMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Acute myeloid leukaemia, Anaemia, Neutropenia, Thrombocytopenia
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, PACLITAXEL reactions: Febrile neutropenia, Upper respiratory tract infection
+serious: 1 patientsex: 1 drugs: CLOTIAZEPAM, DIPHENHYDRAMINE, INSULIN ASPART reactions: Diabetic ketoacidosis, Overdose, Respiratory failure, Suicide attempt
+serious: 1 patientsex: 2 drugs: ANASTROMOL HYDROCHLORIDE reactions: Malignant neoplasm progression
+serious: 1 patientsex: 1 drugs: POLYETHYLENE GLYCOL 3350 reactions: Cervical odontoid syndrome, Decreased appetite, Leukopenia, Pyrexia, Transverse ligament calcification, Wrong technique in product usage process
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENHYDROCODONE, DULOXETINE, FENTANYL, GABAPENTIN reactions: Drug ineffective, Quality of life decreased
+serious: 1 patientsex: 2 drugs: CELECOXIB, LENALIDOMIDE reactions: Hepatic failure, Renal impairment
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, CLONAZEPAM, DIVALPROEX SODIUM, LEVOXOL, HYDRALAZINE HYDROCHLORIDE, LEVOXOL, SIMVASTATIN reactions: Anaemia, Drug ineffective, Myoclonus
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS reactions: Cerebral toxoplasmosis, Cystozoid cystoides, Disorientation, Disturbance in attention, Disorientation, Herniation, Infarction, Mental status changes, Neurotoxoplasmosis, Tachyzoitis
+serious: 1 patientsex: 1 drugs: CEFAZOLIN, CHLORQUINE, DAPTOMYCIN, METHOTREXATE, PREDNISOLONE, VANCOMYCIN reactions: Candida infection, Device related infection
+serious: 1 patientsex: 2 drugs: AMOXICILLIN, LOXOPROFEN, TRANEXAMIC ACID reactions: Meningitis aseptic
+serious: 1 patientsex: 2 drugs: DENOSUMAB reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 2 drugs: CISPLATIN, DOXORUBICIN, ETOPOSIDE, IFOSFAMIDE, PREDNISOLONE, SORAFENIB reactions: Drug ineffective, Hypoglycaemia, Loss of consciousness, Mucosal inflammation, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 1 drugs: CETUXIMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Leukopenia
+serious: 1 patientsex: 1 drugs: VALACYCLOVIR HYDROCHLORIDE reactions: Blood pressure increased, Neurotoxicity
+serious: 1 patientsex: 2 drugs: AMPHOTERICIN B, BISOPROLOL, CIPROFLOXACIN, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB, VANCOMYCIN reactions: Drug ineffective, Pneumonia
+serious: 1 patientsex: 1 drugs: CYTARABINE, DAUNORUBICIN, ETOPOSIDE, METOXANTRONE HYDROCHLORIDE, VORICONAZOLE reactions: Cholecystitis acute, Febrile neutropenia, Septic shock
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, CITALOPRAM HYDROBROMIDE, RISPERIDONE reactions: Drug ineffective, Drug resistance, Sleep disorder, Weight increased
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, DOCETAXEL, FLUCONAZOLE, METHOTREXATE, PACLITAXEL reactions: Hypersensitivity, Off label use
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE reactions: Abdominal fibromatosis
+serious: 1 patientsex: 2 drugs: APIXABAN, ASPIRIN reactions: Haemoptysis
+serious: 1 patientsex: 2 drugs: CLOBETASOL reactions: Cushings syndrome, Drug misuse, Hypomyelination, Off label use, Product use issue
+serious: 1 patientsex: 1 drugs: AMPICILLIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Pathogen resistance
+serious: 1 patientsex: 1 drugs: LISINOPRIL, METFORMIN HYDROCHLORIDE reactions: Acute kidney injury, Hyperkalaemia, Lactic acidosis, Renal tubular necrosis
+serious: 1 patientsex: 1 drugs: BEVACIZUMAB, CAPECITABINE, FLUOROURACIL, IRINOTECAN, LEUCOVORIN, OXALIPLATIN reactions: Cytokine storm, Chills, Diarrhoea, Febrile neutropenia, Neuropathy peripheral, Vomiting
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANIC ACID, DEXAMETHASONE, IBRUTINIB, LEVETIRACETAM, MICAFUNGIN SODIUM, VORICONAZOLE reactions: Aspergillus infection, Gastrointestinal disorder, Nail disorder, Photosensitivity, Toxicity to various agents
+serious: 1 patientsex: 1 drugs: ARIPIPRAZOLE, DOXYCYCLINE, SERTRALINE HYDROCHLORIDE reactions: Bartonella infection, Drug ineffective
+serious: 1 patientsex: 1 drugs: GADOBENAT DIMEGLUMINE reactions: Kounis syndrome
+serious: 1 patientsex: 1 drugs: CYTARABINE, LEUCOVORIN, METHOTREXATE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: DOCETAXEL, FLUOROURACIL, GEMCITABINEGEMCITABINE HYDROCHLORIDE, IRINOTECAN, OXALIPLATIN reactions: Pneumonitis
+serious: 1 patientsex: 2 drugs: ARIPIPRAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ALPRAZOLAM, ASPIRIN, ATORVASTATIN, CLOPIDOGREL BISULFATE, ENOXAPARIN, GLYCERIN, OXYGEN, PANTOPRAZOLE SODIUM, SODIUM CHLORIDE reactions: Gastrointestinal haemorrhage
+serious: 1 patientsex: 1 drugs: ALTEPLASE reactions: Ischaemic stroke
+serious: 1 patientsex: 2 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETPOSIDE reactions: Lipodystrophy acquired
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DEXAMETHASONE, LENALIDOMIDE, ZOLEDRONIC ACID reactions: Acute kidney injury, Febrile neutropenia, Hypocalcaemia, Pancytopenia, Renal failure, Seizure, Tonic-clonic seizure
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, AMPICILLIN SODIUMSULBACTAM SODIUM, LEVOFLOXACIN, MINOCYCLINEMINOCYCLINE HYDROCHLORIDE, MEROPENEM, METHYLPREDNISOLONE, PREDNISOLONE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: BORTEZOMIB, DEXAMETHASONE, DOXORUBICIN, LENALIDOMIDE, IBANDRONATE SODIUM, VINCRISTINE reactions: Osteonecrosis of jaw, Necrotising fasciitis
+serious: 1 patientsex: 2 drugs: ABACAVIR, CALETRA, TENOFOVIR DISOPROXIL FUMARATE reactions: Fanconi syndrome, Wrist fracture
+serious: 1 patientsex: 1 drugs: ABACAVIR, DOLUTEGRAVIR, LAMIVUDINE reactions: Acute kidney injury, Cytomegalovirus infection, Histoplasmosis disseminated, Immune reconstitution inflammatory syndrome, Pancytopenia
+serious: 1 patientsex: 2 drugs: NINTEDANIB reactions: Lung adenocarcinoma
+serious: 1 patientsex: 1 drugs: CISPLATIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, ENOXAPARIN, IFOSFAMIDE, VINCRISTINE reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: AMOXICILLINCLAVULANIC ACID, CEFTRIAXONE, AZITHROMYCIN ANHYDROUS, CEFTRIAXONE SODIUM PHOSPHATE, CEFTRIAXONE SODIUM, PREDNISOLONE reactions: Drug ineffective, Inflammation, Oral cavity ulcer, Pneumococcal infection, Pneumonia, Pneumonia streptococcal, Periodontitis, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent, Pneumonia recurrent,
+serious: 1 patientsex: 1 drugs: ADEFOVIR DIPIVOXIL, LAMIVUDINE reactions: Drug resistance
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Pulmonary toxicity
+serious: 1 patientsex: 1 drugs: CEFTRIAXONE, DOXYCYCLINE, OSELTAMIVIR, WARFARIN reactions: Acute respiratory distress syndrome, Coagulopathy, Drug ineffective, Multiple organ dysfunction syndrome, Paraphimosis, Priapism, Paralysis
+serious: 1 patientsex: 1 drugs: CLOZAPINE reactions: Anaemia, Neutropenic sepsis, Pancytopenia, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: THALIDOMIDE reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: CYCLOSPORINE, METHYLPREDNISOLONE, PREDNISOLONE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 2 drugs: LANREOTIDE ACETATE reactions: Colitis, Drug ineffective, Intestinal perforation
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, PREDNISONE reactions: Drug ineffective, Emotional instability, Nausea, Hirsutism, Nausea, Treatment noncompliance
+serious: 1 patientsex: 2 drugs: BEVACIZUMAB, CAPECITABINE, CETUXIMAB, FLUOROURACIL, IRINOTECAN, OXALIPLATIN reactions: Dermatitis, Neuropathy peripheral
+serious: 1 patientsex: 2 drugs: ETHAMBUTOL HYDROCHLORIDE, ISONIAZID, PYRAZINAMIDE, RIFAMPIN reactions: Granulomatous polyangiitis, Otitis, Peritubulitis, Renal failure, Tubulointerstitial nephritis
+serious: 1 patientsex: 1 drugs: PEMBROLIZUMAB reactions: Myasthenia gravis, Myocarditis
+serious: 1 patientsex: 1 drugs: BRENTUXIMAB VEDOTIN, METHOTREXATE reactions: Choledochoduodenal fistula
+serious: 1 patientsex: 1 drugs: POTASSIUM BROMIDE, TOPIRAMATE reactions: Cardiac arrest, Hyperthermia, Seizure
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, EPIRUBICIN reactions: Disease progression
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, CYCLOPHOSPHAMIDE, HYDROXYCHLOROQUINE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, RITUXIMAB reactions: Acute kidney injury, Cardiac failure, Lupus nephritis, Respiratory failure, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE reactions: Acute myeloid leukaemia
+serious: 1 patientsex: 2 drugs: ARSENIC TRIOXIDE, TRETINOIN reactions: Acute myocardial ischaemia
+serious: 1 patientsex: 1 drugs: AMOXICILLINCLAVULANATE POTASSIUM reactions: Colitis ischaemic
+serious: 1 patientsex: 1 drugs: DOXORUBICIN, FLUOROURACIL, IODIZED OIL, HYDROXYCAPTOCIN, SORAFENIB reactions: Skin reaction
+serious: 1 patientsex: 2 drugs: BISOCODYL, CHLORPHENIRAMINE, HYDROCHLOROTHIAZIDE, SITAGOMINE reactions: Cardiac arrest, Hypokalaemia, Off label use, Ventricular fibrillation
+serious: 1 patientsex: 2 drugs: METHOTREXATE reactions: Epstein-Barr virus infection, Lymphoproliferative disorder
+serious: 1 patientsex: 2 drugs: METHOTREXATE, PREDNISOLONE, TACROLIMUS reactions: Drug ineffective, Drug resistance
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, LEVOFLOXACIN reactions: Interstitial lung disease
+serious: 1 patientsex: 2 drugs: ACYCLOVIR, ETANERCEPT, METHOTREXATE, PREDNISOLONE, TACROLIMUS, TOCILIZUMAB reactions: Herpes simplex keratitis, Ulcerative keratitis
+serious: 1 patientsex: 1 drugs: EVEROLIMUS, LEDIPASVIRSOFOSBUVIR, RIBAVIRIN, VELPATASVIR reactions: Drug interaction, Hepatitis C
+serious: 1 patientsex: 1 drugs: AMPHOTERICIN B, CYCLOSPORINE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, PREDNISONE, RITUXIMAB, TACROLIMUS reactions: Drug ineffective, Leishmaniasis, Treatment failure
+serious: 1 patientsex: 2 drugs: ESTROGENS, LEUPROLIDE ACETATE reactions: Acne, Drug interaction, Fatigue, Hot flush, Injection site rash, Mood altered, Mood swings, Weight increased
+serious: 1 patientsex: 2 drugs: AMANTADINE HYDROCHLORIDE, LEVODOPA reactions: Neuroleptic malignant syndrome
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, LEVOFLOXACIN, METHOTREXATE, SULFAMETHOXAZOLETRIMETHOPRIM reactions: Hyperbilirubinaemia, Neutropenia, Urinary tract infection bacterial
+serious: 1 patientsex: 2 drugs: CLOMIPHENE CITRATE reactions: Abortion spontaneous, Exposure during pregnancy
+serious: 1 patientsex: 1 drugs: ASPIRIN, ATORVASTATIN, CEPHALEXIN, GABAPENTIN, LOSARTAN, METFORMIN HYDROCHLORIDE, TOLTERODINE reactions: Acute kidney injury, Eosinophilia, Pemphigoid, Renal impairment
+serious: 1 patientsex: 1 drugs: ASPARAGINASE, CYCLOPHOSPHAMIDE, CYTARABINE, MERCAPTOPURINE, HYDROCORTISONE, METHOTREXATE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Cerebellar injury, Dysarthria, Dysphonia, Dysphagia, Febrile neutropenia
+serious: 1 patientsex: 1 drugs: CEFOTAXIME SODIUMSULBACTAM SODIUM, LINEZOLID, MEROPENEM, TIGECYCLINE reactions: Acinetobacter infection, Cerebral arachnoiditis, Hydrocephalus, Subdural sac
+serious: 1 patientsex: 2 drugs: LAMOTRIGINE, LEVETIRACETAM, VALPROIC ACID reactions: Precocious puberty
+serious: 1 patientsex: 1 drugs: METHADONE HYDROCHLORIDE, OXYMETHOLONE, OPIUM, TRAMADOL reactions: Acute kidney injury, Drug abuse, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: IBANDRONATE SODIUM reactions: Atypical femur fracture
+serious: 1 patientsex: 1 drugs: RIFAMPIN reactions: Hepatitis
+serious: 1 patientsex: 1 drugs: AMIFOSTINE, BENDAMUSTINE, CYTARABINE, ETOPOSIDE, IBRITUMOMAB TIUXETAN, MELPHALAN reactions: Febrile neutropenia
+serious: 1 patientsex: 2 drugs: DOCETAXEL, PERTUZUMAB, TRASTUZUMAB reactions: Hepatic enzyme increased, Hepatic function abnormal
+serious: 1 patientsex: 1 drugs: PACLITAXEL reactions: Angina unstable, Incorrect route of drug administration, Neointima
+serious: 1 patientsex: 2 drugs: AMIODARONE, ATENOLOL, MAGNESIUM reactions: Drug ineffective, Exposure during pregnancy, Right ventricular tachycardia
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE reactions: Acute kidney injury
+serious: 1 patientsex: 1 drugs: ERLOTINIB, PACLITAXEL reactions: Pulmonary alveolar haemorrhage
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, MAGNESIUM SULFATE, RITODRINE HYDROCHLORIDE, SODIUM CHLORIDE reactions: Acute pulmonary hypertension, Ascites, Cardiothoracic ratio increased, Dyspnoea, Foetal exposure during pregnancy, Premature baby, Uterine contractions
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Death, Metastases to adrenal gland, Metastases to liver, Metastases to lymph nodes, Pyrexia, Respiratory failure
+serious: 1 patientsex: 1 drugs: LENALIDOMIDE reactions: Myeloma, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE, ASPIRIN, ATORVASTATIN, CILOSTAZOL, CLOPIDOGREL BISULFATE, HYDRALAZINE HYDROCHLORIDE, LEVOTHYROXINE, PERIODIZED OIL reactions: Cerebral artery ischaemia, Drug-induced liver injury, Lupus
+serious: 2 patientsex: 2 drugs: CLONIDINE, EZECOPICLONE, GABAPENTIN, MAGNESIUM, NAPROXEN, TOPIRAMATE, VALERIAN RATE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CARBAMAZEPINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, METHOTREXATE, TOCILIZUMAB reactions: Drug-induced liver injury
+serious: 1 patientsex: 2 drugs: AMITRIPTYLINE, TILIDINE reactions: Acute kidney injury, Electrocardiogram QT prolonged, Intentional overdose, Suicide attempt, Toxicity to various agents
+serious: 1 patientsex: 2 drugs: AMLODIPINE BESYLATE reactions: Acute kidney injury, Capillary leak syndrome, Hypoxia, Overdose, Respiratory failure, Shock
+serious: 1 patientsex: 2 drugs: AXITINIB, PAZOPANIB, SUNITINIB reactions: Acute kidney injury, Disseminated intravascular coagulation, Tumour lysis syndrome
+serious: 1 patientsex: 1 drugs: ASPIRIN, CYCLOPHOSPHAMIDE, CYTARABINE, METHOTREXATE, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Drug ineffective, Off label use
+serious: 1 patientsex: 1 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Polyomavirus-associated nephropathy
+serious: 1 patientsex: 1 drugs: AMIODARONE, DOPETHALIDINE, FLECAINIDE, SOTALOL reactions: Atrial fibrillation, Drug ineffective
+serious: 1 patientsex: 1 drugs: PEGINTERFERON ALFA-2B, RIBAVIRIN reactions: Drug ineffective, Pathogen resistance
+serious: 1 patientsex: 2 drugs: ATOVAQUONE, SULFAS reactions: Pneumocystis jirovecii pneumonia, Respiratory failure
+serious: 1 patientsex: 1 drugs: METHOTREXATE, PREDNISOLONE reactions: Interstitial lung disease, Pleural effusion, Pulmonary cryptococcosis
+serious: 1 patientsex: 1 drugs: EXEMESTANE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE ACETATE, TALADAFIL reactions: Drug-induced liver injury, Off label use, Renal failure
+serious: 1 patientsex: 2 drugs: INDOMETHACIN reactions: Foetal exposure during pregnancy, Premature baby
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, GOSERELIN reactions: Squamous cell carcinoma
+serious: 1 patientsex: 2 drugs: BUDENOSIDES, IPRATROPIUM BROMIDE reactions: Anisocoria
+serious: 1 patientsex: 1 drugs: ENTECAVIR, PREDNISONE, TACROLIMUS reactions: Diffuse large B-cell lymphoma, Hepatitis B reactivation
+serious: 1 patientsex: 1 drugs: ANAKINRA reactions: Anaphylactic reaction, Chest discomfort, Drug hypersensitivity, Injection site pruritus, Injection site swelling, Mouth ulceration, Pruritus, Pyrexia, Rash, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash erythematous, Rash ery
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, METHYLPREDNISOLONE, PREDNISOLONE, RITUXIMAB reactions: Tubulointerstitial nephritis
+serious: 1 patientsex: 2 drugs: MYCOPHENOLATE MOFETIL, PREDNISOLONE, TACROLIMUS reactions: Optic ischaemic neuropathy
+serious: 1 patientsex: 2 drugs: CARBOPLATIN, PEMBROLIZUMAB, PEMETREXED reactions: Infection, Performance status decreased, Pelvic pain
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, HYDROXYCHLOROQUINE reactions: Electrocardiogram QT prolonged, Exposure during pregnancy
+serious: 1 patientsex: 2 drugs: CYTARABINE, DASATINIB, RITUXIMAB reactions: Clostridium difficile colitis, COVID-19 pneumonia
+serious: 1 patientsex: 1 drugs: BUPROPION reactions: Tardive dyskinesia
+serious: 1 patientsex: 2 drugs: BISOPROLOL FUMARATE reactions: Dizziness, Drug ineffective, Heart failure, Nausea
+serious: 1 patientsex: 1 drugs: BUPRENORPHINE reactions: Acute hepatic failure, Drug abuse, Jaundice, Nausea, Vomiting
+serious: 1 patientsex: 2 drugs: DAPSONE reactions: Cholestasis, Aplasia pure red cell
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOXORUBICIN, ETOPOSIDE, HYDROCORTISONE, MITOTANE, SUNITINIB reactions: Drug ineffective
+serious: 1 patientsex: 1 drugs: BLEOMYCIN SULFATE, CISPLATIN, ETOPOSIDE reactions: Cerebral venous sinus thrombosis
+serious: 1 patientsex: 2 drugs: ASPIRIN, CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Anuria, Drug ineffective, Renal impairment
+serious: 1 patientsex: 2 drugs: ACETAMINOPHEN, CELECOXIB, CRIZOTINIB, ESOMEPRAZOLE MAGNESIUM MAGNESIUM HYDROCHLORIDE, LEVOCETIRIZINE HYDROCHLORIDE, MAGNESIUM OXIDE, METOCLOPRAMIDE, MORPHINE SULFATE HYDROCHLORIDE, MAGNESIUM OXIDE reactions: Neutropenia
+serious: 1 patientsex: 1 drugs: APIXABAN reactions: Vascular pseudoaneurysm
+serious: 1 patientsex: 1 drugs: CALCITONIN, CALCIUM, CHOLECALCIFEROL, DEFERIPRONE, HYDROCHLOROTHIAZIDERAMIPRIL, MAGNESIUM, METFORMIN HYDROCHLORIDE, SOTALOL, ZOLEDRONIC ACID reactions: Atypical femur fracture
+serious: 1 patientsex: 2 drugs: APIXABAN reactions: Acute kidney injury, Atrial fibrillation, Acute kidney injury, Hypovolaemia, Rhabdomyolysis, Renal haematoma
+serious: 1 patientsex: 1 drugs: CLOZAPINE reactions: Gastrointestinal ischaemia
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, ELTROMBOPAG, HUMAN IMMUNOGLOBULIN G, ROMIPLOSTIM, RITUXIMAB, VINBLASTINE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, METHOTREXATE, PREDNISOLONE, RITUXIMAB reactions: Epstein-Barr virus infection, Post transplant lymphoproliferative disorder
+serious: 1 patientsex: 1 drugs: METHOTREXATE, PREDNISONE reactions: Meningitis listeria
+serious: 1 patientsex: 2 drugs: HYDROCORTISONE, MYCOPHENOLATE MOFETIL, PREDNISONE reactions: Posterior reversible encephalopathy syndrome, Visual impairment
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, RITUXIMAB, VINCRISTINE reactions: Neutropenia
+serious: 1 patientsex: 2 drugs: FLUOCINONIDE reactions: Central serous retinal detachment
+serious: 1 patientsex: 1 drugs: BICALUTAMIDE, LEUPROLIDE ACETATE reactions: Drug ineffective, Prostate cancer recurrent
+serious: 1 patientsex: 1 drugs: ATROPINE, FENTANYL, LIDOCAINE, PROPOFOL, REMIFENTANIL, ROCURONIUM BROMIDE, SEVOFLURANE reactions: Accelerated idioventricular rhythm
+serious: 1 patientsex: 1 drugs: EZETIMIBE reactions: Drug-induced liver injury
+serious: 1 patientsex: 2 drugs: BENDAMUSTINE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, ETOPOSIDE, MELPHALAN, PREDNISOLONE, RITUXIMAB reactions: Hypogammaglobulinaemia, Lymphoenteric fistula
+serious: 1 patientsex: 2 drugs: BETAMETHASONE, CALCITONIN, CALCIUM SULFATE, LABETALOLLABETALOL HYDROCHLORIDE, MAGNESIUM SULFATE reactions: Confusional state, Exposure during pregnancy, Mental status changes, Pancreatitis acute
+serious: 1 patientsex: 1 drugs: CISPLATIN, PACLITAXEL reactions: Drug eruption, Hypersensitivity, Rash pruritic
+serious: 1 patientsex: 2 drugs: ADALIMUMAB, SALAZOPYRIN reactions: Osteonecrosis of jaw
+serious: 1 patientsex: 2 drugs: PROPAFENONE HYDROCHLORIDE reactions: Brugada syndrome, Overdose, Suicide attempt
+serious: 1 patientsex: 1 drugs: CLONAZEPAM, CLONAZEPAM HYDROCHLORIDE, HALOPERIDOL, OLANZAPINE, QUETIAPINE, ZUCLPENTHIXOL reactions: Neuroleptic malignant syndrome
+serious: 1 patientsex: 2 drugs: AZITHROMYCIN ANHYDROUS, CEFTRIAXONE, HYDROXYCHLOROQUINE, TOCILIZUMAB reactions: Foetal death, Foetal exposure during pregnancy, Low birth weight baby, Premature baby
+serious: 1 patientsex: 2 drugs: CALCITRIOL, LEVOTHYROXINE, OCTREOTIDE, VANDETANIB reactions: Metastases to liver, Metastases to lymph nodes, Metastases to intestine, Multiple organ dysfunction syndrome, Thyroid cancer stage IV
+serious: 1 patientsex: 1 drugs: HEPARIN SODIUM reactions: Acute respiratory failure, Cerebral haemorrhage, Haemoglobin decreased, Hemiplegia, Paraneural haemorrhage, Ventricular thrombosis
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, CEFOPERAZONE SODIUM, ORNIDAZOLE, SULBACTAM SODIUM reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: CYCLOPHOSPHAMIDE, DOCETAXEL, DOXORUBICIN reactions: Febrile neutropenia, Sepsis
+serious: 1 patientsex: 1 drugs: AZITHROMYCIN ANHYDROUS, HYDROXYCHLOROQUINE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, TACROLIMUS reactions: COVID-19
+serious: 1 patientsex: 2 drugs: EFAVIRENZ, LAMIVUDINE, TENOFOVIR DISOPROXIL FUMARATE reactions: Stevens-Johnson syndrome
+serious: 1 patientsex: 2 drugs: ENOXAPARIN, WARFARIN reactions: Haematochezia, Shock
+serious: 1 patientsex: 1 drugs: CISPLATIN reactions: Mesenteric ischaemia
+serious: 1 patientsex: 1 drugs: ASPIRIN, HUMAN IMMUNOGLOBULIN G reactions: Haematochezia, Rectal ulcer
+serious: 1 patientsex: 2 drugs: IRBESARTAN reactions: Metastases to skin, Metastases to abdominal wall
+serious: 1 patientsex: 1 drugs: APIXABAN reactions: Haemophilia A, Plasma cell myeloma
+serious: 1 patientsex: 1 drugs: MOXIFLOXACIN, TRIAMCINOLONE ACETONIDE reactions: Scleral abscess
+serious: 1 patientsex: 1 drugs: COLISTIN, METHYLPREDNISOLONE reactions: Drug interaction, Nephropathy toxic
+serious: 1 patientsex: 2 drugs: FLUOXETINE HYDROCHLORIDE, MIANSERIN, SERTRALINE HYDROCHLORIDE reactions: Drug ineffective, Hypomania, Extrapyramidal disorder
+serious: 1 patientsex: 2 drugs: ACETAMINOPHENHYDROCODONE, BUPIVACAINE, FENTANYL, HYDROCODONE HYDROCHLORIDE, LIDOCAINE, METHYLPREDNISOLONE, TRAMADOL reactions: Drug ineffective, Hallucination, Pain, Pudendal neuralgia, Suicide attempt
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, RITUXIMAB, VINCRISTINE reactions: Acute kidney injury, Haemolytic anaemia, Hyperkalaemia, Metastases to kidney, Tumour lysis syndrome
+serious: 1 patientsex: 2 drugs: PREDNISONE, SIROLIMUS, TACROLIMUS reactions: Intestinal angioedema
+serious: 1 patientsex: 1 drugs: ESCITALOPRAM OXALATE, TESTOSTERONE, TRENBOLONE ACETATE reactions: Acute kidney injury, Renal infarct
+serious: 1 patientsex: 1 drugs: AMLODIPINE BESYLATE, METHOTREXATE, TELMISARTAN reactions: Incorrect drug administration duration, Pustular psoriasis
+serious: 1 patientsex: 1 drugs: BACLOFEN, ESCITALOPRAM OXALATE, LORAZEPAM, MIRTAZEPINE, QUETIAPINE reactions: Drug abuse, Drug dependence, Drug dependence
+serious: 1 patientsex: 2 drugs: ESCITALOPRAM OXALATE reactions: Angle closure glaucoma
+serious: 1 patientsex: 2 drugs: PACLITAXEL reactions: Pseudomonas infection, Urinary tract infection
+serious: 1 patientsex: 2 drugs: DOXAZOSIN MESYLATE, HEPARIN SODIUM, ROSUVASTATIN, TOLVAPTAN reactions: Haemorrhage retroperitoneal
+serious: 1 patientsex: 2 drugs: CISPLATIN, MANNITOL, PACLITAXEL, PREDNISONE, SODIUM CHLORIDE reactions: Acute kidney injury, Febrile neutropenia, Off label use, Product use in unapproved indication
+serious: 1 patientsex: 2 drugs: ATORVASTATIN, CLINDAMYCIN, FUSIDIC ACID reactions: Drug interaction, Rhabdomyolysis
+serious: 1 patientsex: 2 drugs: ETHINYL ESTRADIOL, GONAPEPTYL, MESALAMINE, SILDENAFIL CITRATE reactions: Abortion spontaneous, Maternal exposure during pregnancy, Premature delivery
+serious: 1 patientsex: 2 drugs: CLOZAPINE, QUETIAPINE FUMARATE reactions: Akathisia
+serious: 1 patientsex: 1 drugs: AZATHIOPRINE, DOXYCYCLINE, NICOTINAMIDE, PREDNISOLONE reactions: Kaposis varicelliform eruption
+serious: 1 patientsex: 2 drugs: CAPECITABINE reactions: Palmoplantar erythrodysaesthesia syndrome
+serious: 1 patientsex: 2 drugs: PACLITAXEL, TOPOTECAN HYDROCHLORIDE reactions: Anaemia, Dry eye, Dry eye, Dry eye, Dry eye, Glaucoma, Lymphocytopenia, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: CYCLOSPORINE, MYCOPHENOLIC ACID, PREDNISOLONE reactions: Rhabdomyosarcoma
+serious: 1 patientsex: 1 drugs: SORAFENIB reactions: Hepatotoxicity, Off label use
+serious: 1 patientsex: 1 drugs: IMATINIB MESYLATE, PREDNISOLONE reactions: Aplasia pure red cell
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, ETOPOSIDE reactions: Septic shock
+serious: 1 patientsex: 2 drugs: METHYLPREDNISOLONE, PREDNISOLONE reactions: Haemorrhage intracranial, Neuromyelitis optica spectrum disorder
+serious: 1 patientsex: 1 drugs: POTASSIUM PARAMAMINOBENZOATE, SIMVASTATIN reactions: Drug-induced liver injury
+serious: 1 patientsex: 1 drugs: OSELTAMIVIR reactions: Acute respiratory distress syndrome, Acute respiratory distress syndrome, Multiple organ dysfunction syndrome, Septic shock
+serious: 1 patientsex: 2 drugs: DEMEROXIL, PHENERGAN reactions: Nicolau syndrome
+serious: 1 patientsex: 1 drugs: INSULIN NOS, METFORMIN HYDROCHLORIDE reactions: Drug ineffective, Respiratory tract infection
+serious: 1 patientsex: 1 drugs: CARBOPLATIN, EMTRICITABINE, DOLUTEGRAVIR, EMTRICITABINETENOFOVIR DISOPROXIL FUMARATE, PEMBROLIZUMAB, PEMETREXED reactions: Diabetic ketoacidosis, Type 1 diabetes mellitus
+serious: 1 patientsex: 2 drugs: DACARBAZINE, DOXORUBICIN HYDROCHLORIDE, IFOSFAMIDE, MESNA reactions: Acratia, Anaemia, Leukopenia, Neutropenia, Nausea
+serious: 1 patientsex: 2 drugs: NATALIZUMAB reactions: Progressive multifocal leukoencephalopathy
+serious: 1 patientsex: 2 drugs: LENVATINIB reactions: Fatigue, Hyperthyroidism, Thrombocytopenia
+serious: 1 patientsex: 2 drugs: MYCOPHENOLIC ACID, PREDNISONE, TACROLIMUS, VALGANCICLOVIR reactions: Diverticulitis
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE, VINCRISTINE reactions: Device related infection, Staphylococcal bacteraemia
+serious: 1 patientsex: 1 drugs: DIAZEPAM, FLUMAZENIL, OLANZAPINE, QUETIAPINE, THIAMYLAL reactions: Drug ineffective, Pneumonia aspiration
+serious: 1 patientsex: 1 drugs: CISPLATIN, DOCETAXEL, DEXAMETHASONE, FAMOTIDINE, GRANISETRON, PACLITAXEL, PALONOSETRON HYDROCHLORIDE reactions: Diarrhoea
+serious: 1 patientsex: 1 drugs: AMPICILLIN, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULBACTAM SODIUM, AMPICILLIN SODIUMSULB
+serious: 1 patientsex: 1 drugs: CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISOLONE, VINCRISTINE reactions: Cerebrovascular accident, Hemiparesis
+serious: 1 patientsex: 1 drugs: GABAPENTIN reactions: Myasthenia gravis
+serious: 1 patientsex: 1 drugs: FUROSEMIDE, TENOFOVIR DISOPROXIL FUMARATE, SPIRONOLACTONE reactions: Acute kidney injury, Lactic acidosis, Multiple organ dysfunction syndrome
+serious: 1 patientsex: 2 drugs: LAMIVUDINE, NEVIRAPINE, STAVUDINE reactions: Rash maculo-papular
+serious: 2 patientsex: 2 drugs: ARIPIPRAZOLE reactions: Drug ineffective
+serious: 1 patientsex: 2 drugs: DEXAMETHASONE, METHYLPREDNISOLONE, OXYGEN, PREDNISOLONE reactions: Drug ineffective, Posterior reversible encephalopathy syndrome
+serious: 1 patientsex: 2 drugs: DOXORUBICIN HYDROCHLORIDE, TRASTUZUMAB reactions: Cardiotoxicity
+serious: 1 patientsex: 2 drugs: FLUOROURACIL, LEUCOVORIN, OXALIPLATIN reactions: Tumour marker increased
+serious: 1 patientsex: 2 drugs: ERLOTINIB reactions: Drug resistance
+serious: 1 patientsex: 2 drugs: IBUPROFEN, NALTREXONE, ETHINYL ESTRADIOL, VENLAFAXINE HYDROCHLORIDE reactions: Angioedema, Drug eruption, Pruritus, Urticaria
+serious: 1 patientsex: 1 drugs: ADALIMUMAB, AZATHIOPRINE, CYCLOSPORINE, CALCIUM, CHOLECALCIFEROL, CYCLOSPORINE, CYCLOSPORINE HYDROCHLORIDE, IRON, METHYLPREDNISOLONE, PREDNISONE, SIROLIMUS reactions: Drug ineffective
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