---
license: mit
language:
- en
library_name: transformers
tags:
- esm
- esm-2
- sequence classifier
- proteins
- protein language model
---

# ESM-2 Sequence Classifier
This is a small sequence classifier trained on synthetic data generate by GPT-4 
which classifies protein sequences into three categories `enzymes`, `transport_proteins`, and `structural_proteins`. 
To use the model, try running:

``` python3
# Load the trained model and tokenizer
model = EsmForSequenceClassification.from_pretrained("./esm2_t6_8M_UR50D_sequence_classifier_v1")
tokenizer = AutoTokenizer.from_pretrained("facebook/esm2_t6_8M_UR50D")

# Suppose these are your new sequences that you want to classify
# Additional Family 0: Enzymes
new_sequences_0 = [
    "ACGYLKTPKLADPPVLRGDSSVTKAICKPDPVLEK",
    "GVALDECKALDYLPGKPLPMDGKVCQCGSKTPLRP",
    "VLPGYTCGELDCKPGKPLPKCGADKTQVATPFLRG",
    "TCGALVQYPSCADPPVLRGSDSSVKACKKLDPQDK",
    "GALCEECKLCPGADYKPMDGDRLPAAATSKTRPVG",
    "PAVDCKKALVYLPKPLPMDGKVCRGSKTPKTRPYG",
    "VLGYTCGALDCKPGKPLPKCGADKTQVATPFLRGA",
    "CGALVQYPSCADPPVLRGSDSSVKACKKLDPQDKT",
    "ALCEECKLCPGADYKPMDGDRLPAAATSKTRPVGK",
    "AVDCKKALVYLPKPLPMDGKVCRGSKTPKTRPYGR",
]

# Additional Family 1: Receptor Proteins
new_sequences_1 = [
    "VGQRFYGGRQKNRHCELSPLPSACRGSVQGALYTD",
    "KDQVLTVPTYACRCCPKMDSKGRVPSTLRVKSARS",
    "PLAGVACGRGLDYRCPRKMVPGDLQVTPATQRPYG",
    "CGVRLGYPGCADVPLRGRSSFAPRACMKKDPRVTR",
    "RKGVAYLYECRKLRCRADYKPRGMDGRRLPKASTT",
    "RPTGAVNCKQAKVYRGLPLPMMGKVPRVCRSRRPY",
    "RLDGGYTCGQALDCKPGRKPPKMGCADLKSTVATP",
    "LGTCRKLVRYPQCADPPVMGRSSFRPKACCRQDPV",
    "RVGYAMCSPKLCSCRADYKPPMGDGDRLPKAATSK",
    "QPKAVNCRKAMVYRPKPLPMDKGVPVCRSKRPRPY",
]

# Additional Family 2: Structural Proteins
new_sequences_2 = [
    "VGKGFRYGSSQKRYLHCQKSALPPSCRRGKGQGSAT",
    "KDPTVMTVGTYSCQCPKQDSRGSVQPTSRVKTSRSK",
    "PLVGKACGRSSDYKCPGQMVSGGSKQTPASQRPSYD",
    "CGKKLVGYPSSKADVPLQGRSSFSPKACKKDPQMTS",
    "RKGVASLYCSSKLSCKAQYSKGMSDGRSPKASSTTS",
    "RPKSAASCEQAKSYRSLSLPSMKGKVPSKCSRSKRP",
    "RSDVSYTSCSQSKDCKPSKPPKMSGSKDSSTVATPS",
    "LSTCSKKVAYPSSKADPPSSGRSSFSMKACKKQDPPV",
    "RVGSASSEPKSSCSVQSYSKPSMSGDSSPKASSTSK",
    "QPSASNCEKMSSYRPSLPSMSKGVPSSRSKSSPPYQ",
]

# Tokenize the sequences and convert to tensors
# Merge all sequences
new_sequences = new_sequences_0 + new_sequences_1 + new_sequences_2
inputs = tokenizer(new_sequences, return_tensors="pt", padding=True, truncation=True)

# Use the model to get the logits
with torch.no_grad():
    logits = model(**inputs).logits

# Get the predicted class for each sequence
predicted_class_ids = torch.argmax(logits, dim=-1)

# Print the predicted class for each sequence
for sequence, predicted_class in zip(new_sequences, predicted_class_ids):
    print(f"Sequence: {sequence}, Predicted class: {predicted_class.item()}")
```

This is trained using [facebook/esm2_t6_8M_UR50D](https://huggingface.co/facebook/esm2_t6_8M_UR50D), one of the 
Meta AI [ESM-2 models](https://huggingface.co/docs/transformers/model_doc/esm).